Loading...
AZITHROMYCIN IN VITRO ANTIMICROBIAL ACTIVITY AGAINST SELECTED PERIODONTAL BACTERIAL PATHOGENS
Vayner, Regina
Vayner, Regina
Citations
Altmetric:
Genre
Thesis/Dissertation
Date
2022
Advisor
Committee member
Group
Department
Oral Biology
Subject
Permanent link to this record
Collections
Research Projects
Organizational Units
Journal Issue
DOI
http://dx.doi.org/10.34944/dspace/7667
Abstract
Objectives: Azithromycin is a second-generation macrolide active against a wide range of bacteria, including obligate anaerobes implicated as bacterial pathogens in human periodontitis. Clinical studies indicate short-term systemic azithromycin therapy to be beneficial in the treatment of acute periodontal abscesses and as an adjunct to mechanical periodontal therapy of periodontitis patients. Only sparse recent data is available on the susceptibility or resistance of putative periodontal bacterial pathogens to azithromycin, particularly among subgingival isolates from periodontitis patients residing in the United States. Thus, the present degree to which major periodontal bacterial pathogens in United States periodontitis patients exhibit resistance to azithromycin is not known. As a result, the purpose of the present study was to determine the prevalence of in vitro resistance to azithromycin, as compared to metronidazole, among selected red/orange complex periodontal pathogens isolated from severe periodontitis patients in the United States.
Description
Citation
Citation to related work
Has part
ADA compliance
For Americans with Disabilities Act (ADA) accommodation, including help with reading this content, please contact scholarshare@temple.edu