Show simple item record

dc.creatorLiu, X
dc.creatorZhang, J
dc.creatorWu, J
dc.creatorXu, X
dc.creatorTao, L
dc.creatorSun, Y
dc.creatorChen, S
dc.creatorHan, Y
dc.creatorLuo, Y
dc.creatorYang, X
dc.creatorGuo, X
dc.date.accessioned2020-12-15T21:53:51Z
dc.date.available2020-12-15T21:53:51Z
dc.date.issued2020-01-01
dc.identifier.issn1178-7007
dc.identifier.issn1178-7007
dc.identifier.doihttp://dx.doi.org/10.34944/dspace/4490
dc.identifier.otherKW9YT (isidoc)
dc.identifier.other32256097 (pubmed)
dc.identifier.urihttp://hdl.handle.net/20.500.12613/4508
dc.description.abstract© 2020 Liu et al. Purpose: To determine what metabolic abnormalities develop frequently among metabolically healthy adults over time according to different baseline body mass index (BMI) categories. Patients and Methods: A prospective cohort study was performed on 10,805 adults, who were metabolically healthy at the time of the 2008 survey. Participants were divided into four groups: metabolically healthy obese (MHO), metabolically healthy overweight (MHOW), metabolically healthy normal-weight (MHN), and metabolically healthy underweight (MHU). Modified Poisson regression models were used to evaluate the relationship of BMI with the development of metabolic abnormalities. Association rule mining was used to identify the most frequent abnormalities that developed over time. Results: Compared with the MHN group, the adjusted relative risks of the MHO group were 1.57 (95% CI: 1.09–2.27) and 2.08 (95% CI: 1.59–2.73) for developing elevated fasting glucose and elevated blood pressure, respectively, after adjusting for lifestyle behaviours and dietary factors. At the end of follow-up, 33 (19.1%) MHO subjects and 342 (16.6%) MHOW subjects had elevated blood pressure as the predominant metabolic syndrome component, whereas 236 (9.0%) MHU subjects had elevated plasma glucose. The results were similar after stratification by sex. Conclusion: MHO and MHOW subjects developed elevated blood pressure most frequently, and MHU subjects developed elevated blood glucose most commonly, regardless of sex.
dc.format.extent819-834
dc.language.isoen
dc.relation.haspartDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy
dc.relation.isreferencedbyInforma UK Limited
dc.rightsCC BY-NC
dc.rights.urihttps://creativecommons.org/licenses/by-nc/3.0/
dc.subjectmetabolic diseases
dc.subjectdiabetes
dc.subjecthypertension
dc.subjectrisk factors
dc.titleThe impact of BMI categories on metabolic abnormality development in Chinese adults who are metabolically healthy: A 7-year prospective study
dc.typeArticle
dc.type.genreJournal Article
dc.relation.doi10.2147/DMSO.S237550
dc.ada.noteFor Americans with Disabilities Act (ADA) accommodation, including help with reading this content, please contact scholarshare@temple.edu
dc.date.updated2020-12-15T21:53:46Z
refterms.dateFOA2020-12-15T21:53:51Z


Files in this item

Thumbnail
Name:
The Impact of BMI Categories on ...
Size:
2.812Mb
Format:
PDF

This item appears in the following Collection(s)

Show simple item record

CC BY-NC
Except where otherwise noted, this item's license is described as CC BY-NC