HIV RNA Suppression during and after Pregnancy among Women in the HIV Outpatient Study, 1996 to 2015
Genre
Journal articleDate
2018-01-22Author
Patel, MonitaTedaldi, Ellen

Armon, Carl
Nesheim, Steven
Lampe, Margaret
Palella, Frank, Jr.,
Novak, Richard
Sutton, Madeline
Buchacz, Kate
Department
MedicinePermanent link to this record
http://hdl.handle.net/20.500.12613/8391
Metadata
Show full item recordDOI
https://doi.org/10.1177/2325957417752259Abstract
Objective: To examine HIV viral suppression during/after pregnancy. Design: Prospective observational cohort. Methods: We identified pregnancies from 1996 to 2015. We examined HIV RNA viral load (VL), VL suppression (≤500 copies/mL), and antiretroviral therapy (ART) status at pregnancy start, end, and 6 months postpartum. We estimated risk ratios (RRs) and 95% confidence intervals (CIs) for VL nonsuppression. Results: Among 253 pregnancies analyzed, 34.8% of women exhibited VL suppression at pregnancy start, 60.1% at pregnancy end, and 42.7% at 6 months postpartum. Median VL (log10 copies/mL) was 2.80 (interquartile range [IQR]: 1.40-3.85) at pregnancy start, 1.70 (IQR: 1.40-2.82) at pregnancy end, and 2.30 (IQR: 1.40-3.86) at postpartum. Risk of postpartum VL nonsuppression was also lower among women on ART and with VL suppression at pregnancy end (versus those not; adjusted RR = 0.30, 95% CI: 0.17-0.53). Conclusions: Maintaining VL suppression among US women remains a challenge, particularly during postpartum. Achieving VL suppression earlier during pregnancy benefits women subsequently.Citation
Patel M, Tedaldi E, Armon C, et al. HIV RNA Suppression during and after Pregnancy among Women in the HIV Outpatient Study, 1996 to 2015. Journal of the International Association of Providers of AIDS Care (JIAPAC). 2018;17. doi:10.1177/2325957417752259Citation to related work
SAGE PublicationsHas part
Journal of the International Association of Providers of AIDS Care (JIAPAC), Vol. 17ADA compliance
For Americans with Disabilities Act (ADA) accommodation, including help with reading this content, please contact scholarshare@temple.eduae974a485f413a2113503eed53cd6c53
http://dx.doi.org/10.34944/dspace/8358
Scopus Count
Collections
Except where otherwise noted, this item's license is described as Attribution-NonCommercial CC BY-NC