2020-12-082020-12-082016-06-220002-78631520-5126http://dx.doi.org/10.34944/dspace/417327284962 (pubmed)http://hdl.handle.net/20.500.12613/4191© 2016 American Chemical Society. The structurally intriguing terpenes pallambins C and D have been assembled in only 11 steps from a cheap commodity chemical: furfuryl alcohol. This synthesis, which features a redox-economic approach free of protecting-group manipulations, assembles all four-ring systems via a sequential cyclization strategy. Of these four-ring constructing operations, two are classical (Robinson annulation and Mukaiyama aldol) and two are newly devised. During the course of this work a method for the difunctionalization of enol ethers was developed, and the scope of this transformation was explored.7536-7539enChemistry Techniques, SyntheticDiterpenesFuransMolecular StructureOxidation-ReductionArticle2020-12-08