2024-12-182024-12-182023-05-18Yaser Khalid, Michael Lee, Trinava Roy, Rohan Umrani, Kirti Dasu, Neethi Dasu, Nielsen Gabriel, A-16 | Outcomes of Patients With Peripartum Cardiomyopathy (PCM) and Acute Myocardial Infarction (AMI): A Population-Based Study, Journal of the Society for Cardiovascular Angiography & Interventions, Volume 2, Issue 3, Supplement, 2023, 100680, ISSN 2772-9303, https://doi.org/10.1016/j.jscai.2023.100680.2772-9303http://hdl.handle.net/20.500.12613/10768Background: Peripartum cardiomyopathy is a relatively uncommon cause of heart failure. Although the condition is rare, the prevalence of thrombus formation and subsequent embolic events appears to be higher in these women than in the usual heart failure population. Large-scale studies looking for outcomes of patients with PCM and AMI are lacking. We conducted a retrospective cohort study using the NIS to identify outcomes of patients with PCM and associated AMI. Methods: Data were extracted from the National Inpatient Sample (NIS) Database for the years 2015-2019. The NIS was searched for hospitalizations of adult patients with peripartum cardiomyopathy (PCM) with and without a concomitant diagnosis of AMI using ICD-10 codes. We identified 19,960 patients with PCM of which 470 had a concomitant diagnosis of AMI. Multivariate logistic and linear regression analysis was used accordingly to adjust for confounders. STATA software was used for statistical analysis. Results: Patients with PCM and associated AMI had higher inpatient mortality (OR 4.07, CI 1.59-10.43, p<0.001) and total hospital charges ($17,190, CI $10,821-$23,555, p<0.04). However, the there was no statistically significant difference in length of stay (LOS) for those with PCM and AMI compared to those with PCM only. Conclusions: Peripartum cardiomyopathy is defined as the manifestation of heart failure in the last month of pregnancy or within 5 months of delivery in the absence of any other etiology or prior heart disease. On its own, PCM has very high mortality rates ranging between 25% to 50%. Our study has shown that patients with peripartum cardiomyopathy and AMI had increased mortality and total cost of hospital charges. These patients should be monitored very closely and treated aggressively in order to decrease hospital-associated mortality. Disclosures: Y. Khalid Nothing to disclose. M. Lee Nothing to disclose. T. Roy Nothing to disclose. R. Umrani Nothing to disclose. K. Dasu Nothing to disclose. N. Dasu Nothing to disclose. N. Gabriel Nothing to disclose.1 pageengAttribution-NonCommercial-NoDerivs CC BY-NC-NDhttps://creativecommons.org/licenses/by-nc-nd/4.0/Text