TY - JOUR AB - The efficacy and safety of single doses of 6 mg sumatriptan, self-administered subcutaneously by patients using an auto-injector, for the acute treatment of up to three successive attacks of migraine was investigated in a multicentre, open, uncontrolled study in which 178 patients were enrolled. At attack 1, there was an improvement in headache (from severe or moderate to mild or no headache) in 74% of patients at 1 h, and in 82% at 2 h. The incidence of symptoms associated with migraine was decreased after sumatriptan injection. Nausea, vomiting and photo/phonophobia were reported by 72, 54, and 85% of patients, respectively, before the injection to treat attack 1, but by only 22, 12 and 27%, respectively, 2 h after the injection. Migraine recurred within 24 h in 27% of patients, but in 89% of patients was effectively treated with a further dose of 6 mg sumatriptan. Results for attacks 2 and 3 were similar. About 40% of patients experienced at least one adverse event; most of these were mild or moderate in intensity and were transient. It is concluded that 6 mg sumatriptan, self-administered using an auto-injector, is an effective and well tolerated treatment for migraine. Sumatriptan was as effective at attack 3 as at attack 1, and there was no evidence of a change in the incidence or the nature of adverse events with successive uses of the drug. AN - 7958382 DA - Jul-Aug DO - 10.1177/030006059402200404 DP - NLM ET - 1994/07/01 IS - 4 KW - Absenteeism Adolescent Adult Aged Female Humans Male Middle Aged Migraine Disorders/*drug therapy/physiopathology Pain Measurement Self Administration Sumatriptan/*administration & dosage/adverse effects/therapeutic use LA - eng N1 - Clinical Trial Journal Article Multicenter Study Research Support, Non-U.S. Gov't England J Int Med Res. 1994 Jul-Aug;22(4):225-35. doi: 10.1177/030006059402200404. PY - 1994 SN - 0300-0605 (Print) 0300-0605 SP - 225-35 ST - An open study of self-administration of subcutaneous sumatriptan to treat successive attacks of acute migraine. Portuguese Sumatriptan Auto-injector Study Group T2 - J Int Med Res TI - An open study of self-administration of subcutaneous sumatriptan to treat successive attacks of acute migraine. Portuguese Sumatriptan Auto-injector Study Group VL - 22 ID - 3415 ER - TY - JOUR AB - These are the 39 accepted abstracts for IAYT's Symposium on Yoga Research (SYR) September 24-24, 2014 at the Kripalu Center for Yoga & Health and published in the Final Program Guide and Abstracts. AN - 25645134 DP - NLM ET - 2015/02/04 KW - Africa Yoga Project Cbsm Children Electromyography Fitness Healthy aging India Interoceptive awareness Mindfulness Mobile electroencephalography Pranayama Rehabilitation Substance use Yoga Yoga intervention adverse event anxiety aromatase inhibitor aromatase inhibitors arthralgia autism balance bilateral biochemical brain functioning breast cancer breast cancer survivors cancer cancer patients cellular senescence college students community concept mapping cytokines depression eating behavior education effectiveness end-stage renal disease exercise fatigue fear of falling function health hemodialysis intervention malondialdehyde meditation mental health military minority mood multiple sclerosis muscular fitness nationwide survey neurocognitive obesity pain management physical activity physical performance programs psychiatric qualitative quality of life refugees school schools seniors single session social work stress stress/anxiety stroke student tools for the mind total antioxidant status trauma unilateral vision loss wellbeing women workplace yoga postures yoga protocol yoga-exercise yogic breathing program LA - eng N1 - Journal Article United States Int J Yoga Therap. 2014;24:18-38. PY - 2014 SN - 1531-2054 (Print) 1531-2054 SP - 18-38 ST - Accepted scientific research works (abstracts) T2 - Int J Yoga Therap TI - Accepted scientific research works (abstracts) VL - 24 ID - 4084 ER - TY - JOUR AB - BACKGROUND: As mortality rates decline, life expectancy increases, and populations age, non-fatal outcomes of diseases and injuries are becoming a larger component of the global burden of disease. The Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) provides a comprehensive assessment of prevalence, incidence, and years lived with disability (YLDs) for 328 causes in 195 countries and territories from 1990 to 2016. METHODS: We estimated prevalence and incidence for 328 diseases and injuries and 2982 sequelae, their non-fatal consequences. We used DisMod-MR 2.1, a Bayesian meta-regression tool, as the main method of estimation, ensuring consistency between incidence, prevalence, remission, and cause of death rates for each condition. For some causes, we used alternative modelling strategies if incidence or prevalence needed to be derived from other data. YLDs were estimated as the product of prevalence and a disability weight for all mutually exclusive sequelae, corrected for comorbidity and aggregated to cause level. We updated the Socio-demographic Index (SDI), a summary indicator of income per capita, years of schooling, and total fertility rate. GBD 2016 complies with the Guidelines for Accurate and Transparent Health Estimates Reporting (GATHER). FINDINGS: Globally, low back pain, migraine, age-related and other hearing loss, iron-deficiency anaemia, and major depressive disorder were the five leading causes of YLDs in 2016, contributing 57·6 million (95% uncertainty interval [UI] 40·8-75·9 million [7·2%, 6·0-8·3]), 45·1 million (29·0-62·8 million [5·6%, 4·0-7·2]), 36·3 million (25·3-50·9 million [4·5%, 3·8-5·3]), 34·7 million (23·0-49·6 million [4·3%, 3·5-5·2]), and 34·1 million (23·5-46·0 million [4·2%, 3·2-5·3]) of total YLDs, respectively. Age-standardised rates of YLDs for all causes combined decreased between 1990 and 2016 by 2·7% (95% UI 2·3-3·1). Despite mostly stagnant age-standardised rates, the absolute number of YLDs from non-communicable diseases has been growing rapidly across all SDI quintiles, partly because of population growth, but also the ageing of populations. The largest absolute increases in total numbers of YLDs globally were between the ages of 40 and 69 years. Age-standardised YLD rates for all conditions combined were 10·4% (95% UI 9·0-11·8) higher in women than in men. Iron-deficiency anaemia, migraine, Alzheimer's disease and other dementias, major depressive disorder, anxiety, and all musculoskeletal disorders apart from gout were the main conditions contributing to higher YLD rates in women. Men had higher age-standardised rates of substance use disorders, diabetes, cardiovascular diseases, cancers, and all injuries apart from sexual violence. Globally, we noted much less geographical variation in disability than has been documented for premature mortality. In 2016, there was a less than two times difference in age-standardised YLD rates for all causes between the location with the lowest rate (China, 9201 YLDs per 100 000, 95% UI 6862-11943) and highest rate (Yemen, 14 774 YLDs per 100 000, 11 018-19 228). INTERPRETATION: The decrease in death rates since 1990 for most causes has not been matched by a similar decline in age-standardised YLD rates. For many large causes, YLD rates have either been stagnant or have increased for some causes, such as diabetes. As populations are ageing, and the prevalence of disabling disease generally increases steeply with age, health systems will face increasing demand for services that are generally costlier than the interventions that have led to declines in mortality in childhood or for the major causes of mortality in adults. Up-to-date information about the trends of disease and how this varies between countries is essential to plan for an adequate health-system response. FUNDING: Bill & Melinda Gates Foundation, and the National Institute on Aging and the National Institute of Mental Health of the National Institutes of Health. AN - 28919117 C2 - PMC5605509 C6 - EMS74185 DA - Sep 16 DO - 10.1016/s0140-6736(17)32154-2 DP - NLM ET - 2017/09/19 IS - 10100 KW - Adolescent Adult Age Distribution Aged Aged, 80 and over Cause of Death/*trends Child Child, Preschool Communicable Diseases/mortality Disabled Persons/*statistics & numerical data Female Global Burden of Disease/*statistics & numerical data Global Health/statistics & numerical data Humans Incidence Infant Infant, Newborn Male Middle Aged Noncommunicable Diseases/mortality Prevalence Sex Distribution Wounds and Injuries/mortality Young Adult LA - eng N1 - 1474-547x GBD 2016 Disease and Injury Incidence and Prevalence Collaborators MC_UU_12017/13/Medical Research Council/United Kingdom MC_UP_A620_1015/Medical Research Council/United Kingdom P01 HD031921/HD/NICHD NIH HHS/United States R01 MH110163/MH/NIMH NIH HHS/United States MC_U147585827/Medical Research Council/United Kingdom U01 AI096299/AI/NIAID NIH HHS/United States U01 AG009740/AG/NIA NIH HHS/United States MC_UU_12011/2/Medical Research Council/United Kingdom P30 AG047845/AG/NIA NIH HHS/United States D43 TW009775/TW/FIC NIH HHS/United States MC_U147585819/Medical Research Council/United Kingdom 201900/Wellcome Trust/United Kingdom SPHSU13/Chief Scientist Office/United Kingdom MC_UP_A620_1014/Medical Research Council/United Kingdom R01 HD084233/HD/NICHD NIH HHS/United States R01 HD087993/HD/NICHD NIH HHS/United States SPHSU15/Chief Scientist Office/United Kingdom SCAF/15/02/Chief Scientist Office/United Kingdom HHSN271201300071C/AG/NIA NIH HHS/United States MR/K013351/1/Medical Research Council/United Kingdom MC_UU_12011/1/Medical Research Council/United Kingdom N01HC25195/HL/NHLBI NIH HHS/United States R01 AI124389/AI/NIAID NIH HHS/United States Wellcome Trust/United Kingdom UL1 TR001881/TR/NCATS NIH HHS/United States MC_UU_12017/15/Medical Research Council/United Kingdom G0400491/Medical Research Council/United Kingdom CDF-2011-04-048/Department of Health/United Kingdom P01 AG041710/AG/NIA NIH HHS/United States MC_U147585824/Medical Research Council/United Kingdom R01 AI112339/AI/NIAID NIH HHS/United States Journal Article Lancet. 2017 Sep 16;390(10100):1211-1259. doi: 10.1016/S0140-6736(17)32154-2. PY - 2017 SN - 0140-6736 (Print) 0140-6736 SP - 1211-1259 ST - Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016 T2 - Lancet TI - Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016 VL - 390 ID - 3961 ER - TY - JOUR AB - Background: Social isolation, loneliness and anxiety-depressive states are emerging health conditions in the elderly. Research question: To assess whether a 4-month programme of physical activity in a group improves the emotional, social and quality of life situation in a sample of subjects over 64 years old people. Methods: Multi-centre randomized clinical trial of two groups. Study population: Patients older than 64 years assigned to three primary care teams from different locations. Inclusion criteria: Submit a score <32 on the DUKE-UNC-11 social support scale, or >12 on the Beck Depression Scale, or >10 on the Generalized Anxiety Scale (GAD-7), at the start of the study. The intervention group participated in a group physical activity program for 4-months that consisted of progressively walking sessions two days a week, 60-150 minutes long depending on the physical condition of each participant. Results: Enrolled were 94 patients who met the inclusion criteria. Mean age was 74 years (SD 5.18) and 76.6% were women. No significant differences were found at the beginning of the study between the two groups in relation to the outcome of the scales evaluated. Once the intervention was completed, improvement in the quality of life and social support was detected in the intervention group (p<.05). Both groups improved the depression and anxiety clinic but the improvement in the participants of the intervention group was higher. Those with initial depression improved 8.6 points on the scale, compared to the control that improved 3.3 points, with the final average of 17.4. Those who presented initial anxiety improved 8 points (final average: 7.5 points, cut-off point for the diagnosis of anxiety 10), compared to the control that improved 5.1 points. Conclusion: The results of this study indicate that the program developed has positive effects on improving the quality of life, social support and depression and anxiety clinic. Background: Tourism represents 45% gross domestic product in Balearic Islands. Working as a hotel housekeeper (HH) has been associated with important morbidity, especially musculoskeletal, chronic pain, a significant number of sick leaves, a high consumption of medication, poor psychological well-being and worse quality of life. Research question: Explore perceptions and opinions regarding the HH's work and health problems. Estimate and evaluate HH's health determinants, the exposition to several occupational risk factors, their lifestyles and health problems and their quality of life. Methods: Design: mixed methods: (1) exploratory qualitative study (QS) including 10 semi-structured interviews and six focus groups; (2). descriptive study (DS): individual interviews and clinical medical records. Inclusion criteria: older than 18 years, had worked during the last summer season in the Balearic Islands. Analysis: QS: transcription and content analysis; DS: descriptive statistical analysis. Results: QS: Identified positive aspects of their work: timetables, relationship with co-workers, attending clients. Highlighted negative aspects: working conditions, hard physical workload, stressful duties and insufficiently rewarded. HH associated their health problems with their work; coping strategies: self-medication or visiting their general practitioner. DS: 1.043 HH included. Mean age 43.3 years, mean working years as HH 10.7 years. Mean rooms/day: 18.1 (+/- 6.5); mean beds/day: 44.6 (+/- 20.7). HH reported often pain during the last summer season: 68.2% (IC 95% 65.3-71.0) low back pain; 60.9% (IC 95% 57.8-63.8) wrist and hands; 55.3% (IC 95% 52.2-58.3) cervical. 41.6% and 35.1% self-reported regular and poor health status, respectively. Conclusion: HH perceived hard and stressful working conditions, partly justified by the number of rooms and beds made per day. They also perceived health problems related to their work. HH frequently reported pain during the last summer season. Moreover, they perceive regular or poor health status, weaker than women from the same social class do. Background: Gender-based violence (GBV) is a public health and human rights issue, being highly prevalent (12-51%), repetitive and having a severe impact on women's health, with a high sanitary and social cost. Primary care has a key role in detection and management. There is low detection and delay in diagnosis. There is a lack of preparation to recognize abuse, especially in the approach and action after detection. Greater awareness and sensitization is required. Research question: Can a brief specific training intervention in GBV imparted to primary health care professionals in their primary health centre increase knowledge, improve attitudes and skills? Methods: A cluster-randomized clinical trial was carried out in Vigo area primary health centres with at least 20 health care professionals. A basal evaluation was made through a validated inquiry (PREMIS), which they had to retake after three months. In the intervention centres, a clinical session was imparted. pResults: Out of 264 primary health care professionals, 145 participated. There was a 63.5% loss out of 145 professionals. A statistically significant difference was detected in the field of knowledge, increasing an average of two points on a scale from 0 to 5 in these aspects: how to make appropriate questions; connections between GBV and pregnancy; why do not they leave their partners; risk determination and phases of GBV. There was also a decrease in the idea that if the patient does not recognize gender violence, there is very little that can be done. No significant differences were detected in the detection and follow-up. Conclusion: Significant differences were found in the knowledge and attitude sections after performing the intervention to the professionals. The results support the implementation of continuous brief training on GBV in primary care. Background: Out-of-hours (OOH) primary care is a topic of great interest in European countries. Reasons for this are similar across borders: to guarantee continuity of care with decreasing numbers of health care workers and to guard equity in OOHcare for all patients. In OOHcare research, valid and accessible research data are needed to fill the knowledge gap. iCAREdata aims to offer valid and immediately available information from OOHcare. Research question: How feasible is it to collect, store and link data of different OOH services in Belgium and to improve data quality registration? How useful are aggregated data to inform stakeholders, to evaluate (the quality of) services in OOH care and the effects of interventions? Methods: As a first achievement, data flows, encryption and encoding were carefully designed and implemented. Solid cooperation with the federal eHealth web services as a trusted third party was crucial. Ethical approval and approval by the data protection authority was obtained. Clear agreements were established concerning access control. A strict code of conduct was agreed upon. A steering committee was established to guard the procedures. Results: First data were collected in 2015. iCAREdata now receives +/- 3000 unique patient contacts per weekend, spread over 14 general practice cooperatives, and covering about a quarter of the Flemish population. Aggregated data, directly processed, are provided weekly on . This portal site offers an overview of, among others, the latest diagnostics, drug prescriptions and workload. iCAREdata project also collects data from emergency departments in hospitals and community pharmacists and link them to evaluate further OOH primary care. Conclusion: Developing a research database on OOHcare is feasible. The iCAREdata project succeeds in an automated output every week, offering insights on the evolution of morbidity, services and effects of interventions. Careful validation and interpretation of the data is a crucial ongoing challenge. Background: More than half of decompensations of heart failure are attended in primary care setting. No score that helps to ascertain the short-term prognosis in these patients. Research question: To develop and validate a short-term score (30 days) to predict hospitalizations or death in patients attended in primary care as a consequence of decompensation of heart failure, based on variables easily measurable in primary care setting Methods: Prospective multinational cohort study including patients treated because of a heart failure decompensation in primary care setting. There were a derivation (Spain) and a validation cohort (nine European countries). Results: The derivation cohort included 561 patients, women were 56%, mean age was 82.2 (SD 8.03) years and 31.5% of patients were hospitalized or died in the first month. In the validation cohort, 238 patients were included, women were 54%, mean age was 79.0 (10.4) years and 26.9% of patients were hospitalized or died in the first month. According to the multivariate models, sex, age, hospital admission due to heart failure the previous year, and a heart rate greater than 100 beats/minute, orthopnoea, paroxysmal nocturnal dyspnoea, NYHA functional stage III or IV, saturation of oxygen lower than 90% or an increase in the dyspnoea at the consultation with the General practitioner were included in the HEFESTOS-SCORE. The multivariate model including these variables showed a good calibration (Hosmer-Lemeshow p=.35) and discrimination (AUC 0.81, 95% CI 0.77-0.85). In the validation cohort, the model presented an adequate external validation with good calibration (Hosmer-Lemeshow p=.35) and discrimination (AUC 0.74, 95% CI 0.67-0.82). Conclusion: The HEFESTOS-SCORE, based on clinical and demographical variables easily measurable in primary care is a useful tool to stratify the short-term hospitalization and mortality in patients attended because of a heart failure decompensation. Background: Despite recommendations against long-term benzodiazepine (BZD) use, they are often prescribed during months or years in primary care. Research question: To determine facilitators and barriers that explain the variation in implementation of a primary care educational and feedback intervention targeted to general practitioners (GPs) to reduce BZDs prescriptions. Methods: A hybrid type I clinical trial: qualitative data to evaluate the implementation outcomes. Three health districts of Spain: Balearic Islands, Tarragona-Reus district (Catalonia) and Arnau de Vilanova lliria district (Valencia). Forty stakeholders (GPs) participated in five focus groups; they were selected based on their effectiveness of the intervention results: high (three groups) or low (two groups) and individual interviews to two GP of low efficiency. The Consolidated Framework for Implementation Research (CFIR) was used to guide collection and analysis of qualitative data. Two researchers evaluated the qualitative data of the focus groups by the Codebook and Rating Rules of CFIR, independently. Results: Of the 31 CFIR constructs assessed, three constructs strongly distinguished between GPs with low versus high success of the intervention (intervention complexity, individual state of change, key stakeholders engaging), seven additional constructs weakly distinguished (adaptability, external policy and incentives, implementation climate, compatibility, relative priority, self-efficacy, formally appointed internal implementation leaders), 10 had insufficient data to assess and 11 were non-related to the success of the intervention. Conclusion: We identified the constructs that explain the variation in the effectiveness of the intervention; this information is relevant to redesign successful implementation strategies focused on these constructs to implement the BENZORED intervention in health services. Background: Despite recommendations against long-term benzodiazepine (BZD) use, they are often prescribed during months or years in primary care. Research question: To evaluate the effectiveness of a primary care educational and feedback intervention targeted to general practitioners (GPs) to reduce BZDs prescriptions. Methods: Design: A two-arm parallel cluster randomized clinical trial. Settings: Primary Healthcare centres from three health districts of Spain: Balearic Islands (IbSalut), Catalonia (Institut Catala de la Salut; Tarragona-Reus district) and Community of Valencia (Conselleria de Salut Universal; Arnau de Vilanova lliria district). Participants: All GPs from the health districts included were invited to participate. Ninety percent of the GPs accepted to participate. Intervention: GPs received an educational two hours workshop training about the rationale for prescribing BZDs and deprescribing strategies for long-term BZD users, audit and monthly feedback about their prescription and access to a support web page with information to help them and leaflets to give to the patients. Control group: GPs did not receive any component of the intervention. Outcomes: Defined daily dose (DDD)/1000 inhabitants/year (DHD) of BZDs prescribed by GP at 12 months. Proportion of long-term BZD users (>6 months) and in patients aged 65 or more at 12 months. Statistical analysis: Generalized mixed linear random effect models to account for clustering at the level of healthcare centre and all analyses were based on an intention to treat principle. Results: We included 749 GPs and 49 (6.5%) were lost to follow-up. Adjusted difference between groups in DHD at 12 months was -3.26 (-4.87;-1.65), p<.001. The differences in the proportion of long-term BZD users was -0.39 (-0.58;-0.19), p<.001 and in patients older than 65 was -0.87 (-1.35;-0.26), p=.004. Conclusion: An educational and feedback intervention targeted to GPs is effective to reduce BZD prescription in primary care. Background: Patients who might also go to the general practitioner (GP) frequently consult emergency departments (ED). This leads to decreased efficiency, high workload at the ED and additional costs for both government and patient. Research question: The primary outcome is the proportion of patients who enter the ED and are handled by the GP after triage. Secondary outcomes: Referral rate to the ED by the GP, proportion of patients not following the triage advice, compliance of the nurse to the triage-instructions and health insurance expenditures. Furthermore, facilitators and barriers will be studied and an incident analysis will be performed. Methods: This is a randomised controlled trial with weekends serving as clusters. Patients presenting at the ED during OOH are triaged and allocated to either ED or GP by a trained nurse using an extension to the Manchester Triage System (MTS). During control clusters, all patients remain at the ED. Data are collected using a database for OOH care (iCAREdata). Results: So far, 296 out of 2733 (11%) patients were allocated to the GP. Two-thirds (194) of these patients did go to the GP leading to a primary outcome of 7% for 14 intervention weekends. Only eight patients were referred back to the ED. Compliance of the nurse to the extended MTS was 93%, in 6% of the cases the nurse chose ED instead of GPC and in less than one percent GPC instead of ED. The nurses chose higher urgency categories and more discriminators, leading to the GP during intervention clusters. Using an automated system, these results are updated weekly, on our poster, we will show more results that are complete. Conclusion: These first results reveal a low efficiency but a high safety of the intervention. More prolonged data collection combined with a process analysis and cost efficiency study is necessary before definitive conclusions can be drawn. Background: Low back pain is a multifactorial condition with individual and societal impact. Psychosocial factors play a larger prognostic roll. Therefore, earlier multidisciplinary treatment strategy (physical, psychological and social/occupational) could be applied to search improvement in fear-avoidance beliefs with positive effect in the evolution of low back pain. Research question: Evaluate the effectiveness of a biopsychosocial multidisciplinary intervention (physiotherapy, cognitive-behavioural and pharmacological therapy) through the changes in fear-avoidance beliefs (FABs), in working population with sub-acute non-specific LBP, compared to usual clinical care at 3 and 12 months. Methods: A cluster randomised clinical trial, conducted in 39 Primary Health Care Centres (PHCC) in Barcelona. Participants between 18 and 65 years old (n = 369; control group =188, PHCC 26 and intervention group =181, PHCC 13). Control group received usual care, according to guidelines. Intervention group received usual care plus a biopsychosocial multidisciplinary intervention (sessions 10 hours/total). The main outcome was the Fear-Avoidance Beliefs questionnaire (FABQ). Other outcomes: Evolution to chronicity. Assessment at baseline, 3 and 12 months. Analysis was by intention to treat and analyst blinded. Multiple imputations. Results: Of the 369 enrolled patients with LBP, 421 (84.0%) provided data at the three months of follow-up, and 387 (77.2%) at 12 months. Mean age of study subjects at baseline was 45.1 (SD: 10.4) years-old and 61.2% were women. At baseline, there were no differences. Both groups showed a decrease in FABQ (FAB physical and FAB-work) at three months and twelve months, with a significant difference at long-term. At FAB-physical performance, there was no significant difference over the follow-up time and at FAB-Work, a substantial difference at 12 months between groups. Conclusion: A multidisciplinary biopsychosocial intervention showed a positive effect in FABs by improving fear behaviours and avoidance at work. Community participation in primary healthcare is enshrined in international policies since the 1970s and has been re-emphasised since then, most recently in the 2018 WHO Astana Declaration (). The concept comes from a social justice perspective. It emphasises that the participation of communities who experience poverty and social exclusion is essential to the development of primary health care services shaping these services and making them relevant to those with the greatest need. This is important if we are to address the well-documented Inverse Care Law. There is, however, a translational gap between policy and practice. The stability of policies for community participation in primary healthcare is patchy. The implementation of policies into conventional ways of working is patchy. Where implementation has occurred, the coverage of community participation initiatives can be patchy - not all community members are involved. The literature shows a pattern of exclusion whereby so-called 'hard to reach' groups are not adequately involved in primary healthcare decision-making. This is the case for refugees and migrants who arrive to settle and integrate into host countries in Europe. The recent WHO Strategy and Action Plan for Refugee and Migrant Health (2016; ) is a call for action to disrupt this pattern of exclusion and improve the health of refugees and migrants. Drawing on the rich tradition of participatory health research is a valuable way forward because it provides important concepts, tools and techniques for research that is more inclusive and primary care practice. This presentation will describe innovative examples of success in family practice settings from around Europe. These have brought together refugees and migrants with primary care stakeholders and enabled them to work together to introduce and sustain changes in clinical practice. This evidence can be used to guide and strengthen community participation in primary healthcare, for all. Background: Community participation is essential for effective implementation of research programmes in primary healthcare (PHC) but also appropriate interpretation of results and optimal delivery of subsequent care. Stakeholder engagement undertaken under defined and evaluated frameworks may be key for the establishment of concrete collaboration and communication between communities and other parties involved in research. This abstract aims to report on community and stakeholder engagement methodologies, plans and activities of European research projects conducted in Crete, Greece. Research question: Could a consensus be reached regarding the methods and tools for enhancing stakeholder engagement in community-oriented PHC research? Methods: Examined programmes included RESTORE (FP7), FRESH AIR (Horizon2020) and VIGOUR (Health Programme). Identified methodologies included Normalisation Process Theory, Participatory Learning and Action, Five Steps of Stakeholders' Engagement, establishment of Stakeholder Engagement Groups under the 9 C's model (commissioners, customers, collaborators, contributors, channels, commentators, consumers, champions, competitors) and Structured Democratic Dialogue. These were implemented to a range of stakeholders, including community members, patients, migrants, Roma populations, healthcare professionals and policy-makers. Qualitative research (focus groups, individual interviews) and Thematic Content Analysis were used for design and analysis of engagement activities. Results: In RESTORE, migrants and other stakeholders selected guidelines and training supporting cross-cultural communication in PHC consultations, based on their own needs and expectations. Community members, healthcare professionals and healthcare authorities were actively involved in FRESH AIR by identifying local priorities and contextual factors for designing project interventions, providing access to communities and supporting dissemination of project achievements. In VIGOUR, multidisciplinary stakeholders were brought together and formulated a joint ambition statement for the future of integrated care in Crete. Conclusion: Various stakeholder engagement methods with documented effects are currently available. Their systematic identification, appraisal, synthesis and consolidation may serve with enhancing community participation in PHC, sustaining research results and translating findings into appropriate actions. Background: Screening for prostate cancer remains controversial, implying a trade-off between benefits and harms, and a shared decision-making process has been advocated. Decision aids are evidence-based tools that improve decision quality. For limited-resource countries, translating and making cultural adaptations to high-quality decision aids is a reasonable alternative to developing new ones. Research question: We aimed to translate and culturally adapt an English language patient decision aid addressing prostate cancer screening, so that Portuguese men can use it. Methods: We followed the European Centre for Disease Prevention and Control's (ECDC) five-step, stakeholder-based approach to adapting health communication materials: (1) selection of materials and process coordinators; (2) early review; (3) translation and back translation; (4) comprehension testing with cognitive semi-structured interviews; (5) proofreading. Cognitive interviews were conducted with 15 men, ages 55-69, from the Oporto district local community to refine the decision aid after its translation. Content analysis was performed using Ligre (TM) software. Results: Five main themes are presented: informational content, information comprehension, socio-cultural appropriateness, feelings and primary message, and personal perspective concerning prostate cancer screening. For each theme, illustrative quotes extracted from men's interviews are presented. Most men found the translated version of the decision aid to be clear, comprehensive and appropriate for its target population, albeit some suggested that medical terms could be a barrier. The data collected from men's interviews allowed the researchers to clarify concepts and expand existing content. Conclusion: The final version of the decision aid can be used in the real world clinical setting and our ECDC based approach can be replicated by other workgroups to translate and culturally adapt decision aids. What are we talking about when we talk about value? In 2006, Michael Porter and Elizabeth O. Teisberg published; Redefining Health Care, Creating Value-Based Competition on Results, Harvard Business School Press. Affirming that payers and providers, including doctors and nurses, are very concerned in demonstrating that they work a lot, and very little, or nothing, in assessing what their work contributes to the health of people and communities. Michael Porter is famous in the business world for his work on competitiveness based on the value of products and services. He has introduced this concept in the provision of health services, all summarised in a phrase: Health systems should seek to obtain the maximum possible value for the health of people for every dollar they spend. However, to define the value in healthcare, the patient must be introduced into the equation, so, in Porterian terms, the value is the perception that people have about clinical effectiveness and the costs of therapeutic processes. Clinical effectiveness is measurable from epidemiology (to be readmitted to a hospital fewer times or living longer); value, on the other hand, is reflected by people's experience. We need to ask questions such as do patients with advanced diseases want to live longer, or they want to enjoy the highest quality of life possible. Depending on the response, we can develop different delivery models. What is value-based healthcare? According to NEJM Catalyst, Value-based healthcare is a healthcare delivery model in which providers, including hospitals and physicians, are paid based on patient health outcomes (). Under value-based care agreements, providers are rewarded for helping patients improve their health, reduce the effects and incidence of chronic disease, and live healthier lives in an evidence-based way. How to achieve a Value-Based Healthcare Model The following six drivers are the key to make a primary health care system a value-based healthcare model: 1. Prioritising patient-centred care. 2. From clinical pathways to care delivery value chains. 3. Promoting the right care and reducing medical overuse. 4. Turning a fragmented model into another integrated model. 5. Creating the enabling environment for healthcare transformation. 6. Fostering community health. How to develop a Value-Based Community Health Michael Marmot states that if the determinants of health are mostly social, solutions must also be social, so to improve the quality of community life, political systems require economic, housing, education, security and infrastructure programs (Am J Public Health. 2014;104:S517-S519). Nevertheless, the healthcare system must know how to adjust resources according to the social circumstances of each community and to understand how to provide a health-oriented vision of all the social programs. On the other hand, community health is an intervention model that aims to improve the health of a defined community that should operate from primary care services to adjust their actions to the social reality of each territory. Background: Geriatric care needs to be increased with growing elderly populations. The Borgholm jurisdiction in the Baltic Island of oland (Kalmar region) has an older than average senior population and had difficulties recruiting primary care physicians (PCPs) resulting in high elderly hospital care consumption. Research question: Could a new model of geriatric care be able to decrease the hospital care needs of Borgholm as compared to the rest of Kalmar region? Methods: A new model of care was developed in Borgholm 2016-2017 where the PCP list was limited to 1000 patients, daily slots for PCP home care visits could be booked by community nurses or ambulance nurses and PCPs had daily anticipatory care planning contacts with Kalmar hospital staff. Results: Between 2014 and 2018, Borgholm home care patients >75 years old increased by 70% vs. a 2% decrease for the rest of Kalmar region. Similarly, Kalmar emergency department visits decreased by 19% in Borgholm vs. 9% increase for the rest of Kalmar. Also, Kalmar hospital care episodes decreased 7% in Borgholm vs. 13% increase for the rest of Kalmar; Kalmar hospital outpatient visits decreased 8% in Borgholm vs. 21% increase for the rest of Kalmar; total care consumption for >75 years old decreased 4% in Borgholm vs. a 10% increase for the rest of Kalmar region. Conclusion: A new geriatric care model consisting of a comprehensive collaboration between strengthened primary care and community care, hospital care and ambulance care was associated with a reduction in total care consumption for senior citizens in a rural Swedish jurisdiction. Background: Primary health care, the general practitioner, plays a critical role for early identification and care of patients with dementia. Early diagnosis of dementia allows starting therapy and improving the quality of life of the patients. Research question: To estimate the prevalence and care of patients with dementia in North Macedonia. Methods: Forty-six general practitioners (GPs) surgeries from 20 cities in Macedonia took part in the project. All individuals age over 65 years with a diagnosis of dementia were identified from GP electronic disease registers. Results: Based on the diagnosis, 450 (3.5%) patients were identified from a total population of 12,926 over 65s. The most common dementia was Alzheimer's dementia 294 (65.3%) followed by vascular dementia 27.11%. The average age of respondents in the study was 77.5 +/- 8.2 years, with 50% patients under the age of 79 years, 65.6% were female and 68.4% were with elementary school. In the entire sample, most of the patients diagnosed with dementia 195 (43.3%) said they lived with another family member. The most common risk factor was hypertension (85.1%), followed by stroke/ transitory ischemic attacks (29.3%) and equal percentage, i.e. 26.4% of patients had high levels of cholesterol and diabetes. To 242 (53.8%) acetylcholinesterase inhibitors were prescribed (donepezil, rivastigmine, galantamine), 77 (17.1%) memantine, while 247 (54.9%) another OTC therapy. 227 (50.4%) reported that they did not receive treatment. An additional analysis of the reasons for not receiving treatment was made on this sample of patients who did not receive treatment. It was found that in the majority of these patients (more than 50%) the reason for not receiving therapy was that it was not prescribed, in 142 (62.6%). Conclusion: This is the first national representative study of dementia prevalence in North Macedonia. Those data can provide information for healthcare needs people with dementia. Background: Emotional experience for medical students during clinical internships is often ignored. Yet, its influence on professional skills is certain. Research question: 'What is the emotional experience of second and third-year medical students during their first clinical internship? How do they perceive the management of their experience by their supervisors?' Methods: A qualitative study was conducted with 12 students in their second or third year of medical training at the University of Lille, in France, between 2016 and 2019. Interviews were carried out comprehensively for a total of 17 hours. Following a grounded theory approach, the analysis terminated when data were sufficient to offer a conclusive model. Results: Emotional experience during clinical internship was rich and intense. It was most often ignored and was not taken into account in the development of professional skills. The organized management was deficient. Informal training existed: when a wilful student met a dedicated teacher. Students would have welcomed a possibility to experience intense emotions in a protective environment, and only then in an empowering environment. They expressed the same desire about early exchanges on the experiences of the internship. A modelling of the informants' emotional experiences was realized in the form of three diagrams. Conclusion: Students ask to be challenged to face patients, and then to be listened to about it. Possible interventions are trauma prevention and detection of malaise in the workplace; teaching of humanist values; providing experience and reflexivity through new pedagogical means (such as cinema, theatre, literature, writing), or relational means (such as exchange groups, companionship, solidarity commitment, immersive internships and tutoring); and training supervisors. Background: Oral anticoagulants (OAC) reduce the risk for stroke and death from all causes in patients with non-valvular atrial fibrillation (NVAF). Research question: To explore adherence rates to OAC among patients with NVAF and to compare head-to-head adherence rate of different medications in long-term chronic use. Methods: We conducted a population-based cohort study Clalit Health Services, Israel. All patients, 30 years and over, with a diagnosis of NVAF before 2016 and were treated with OAC were included. We included patients that filled at least one prescription per year in the three consecutive years 2016-2018. We analysed all prescriptions that were filled for the medications from 1 January 2017 to 31 December 2017. We considered purchasing of at least nine monthly prescriptions during 2017 as 'good medication adherence.' Results: Twenty-six thousand and twenty-nine patients with NVAF who were treated with OAC were identified. Ten thousand and two hundred and eighty-four (39.5%) were treated with apixaban, 6321 (24.3%) were treated with warfarin, 6290 (24.1%) were treated with rivaroxaban 3134 (12.0%) were treated with dabigatran. Rates of good medication adherence were 88.9% for rivaroxaban, 84.9% for apixaban, 83.6% for dabigatran and 55.8% for warfarin (p<.0001). Good adherence with OAC was associated with lower LDL cholesterol and glucose levels. Advanced age was associated with higher adherence rates (p<.001). SES was not associated with medication adherence. Conclusion: Adherence rates to DOAC among patients with NVAF are high and are higher than the adherence rate to warfarin. It should be taken into consideration when choosing OAC treatment for NVAF. Background: In France, cervical cancer screening by pap-smears should be conducted triennially. Screening statistics are based on the number of cytology examinations of smears reimbursed by the Health Insurance appearing in the claim databases. The percentage of screened women is lower based on these data than on declarative surveys. If surveys are overestimating the number of screened women, it is likely that claim databases underestimate it. Research question: The primary objective was to determine the underestimation of screened women in claim databases. The secondary purpose was to estimate the proportion of female patients not reachable by their GP for a cervical cancer screening in an organized screening trial. Methods: The population was the 6327 female patients aged 30-65 years of the 24 GP investigators of the PaCUDAHL-Ge trial. We compared the lists of their female patients that had no cytology of Pap test reimbursed during the three prior years, extracted from the Health Insurance claim databases in 2015 and 2018. We selected the patients appearing on both lists meaning they had not responded to the invitation of their GP to be screened in the trial. We searched in the GPs' records valid reasons not to be screened (hysterectomy, history of cervical lesion, pregnancy, other conditions making screening irrelevant) or evidence of screening. Results: The total number of 'unscreened' women in 2018 was 2731, 1737 patients appeared on both lists, 1522 could be included for analysing, 65 had been screened, 95 had hysterectomy, three had a history of cervical lesion, nine were pregnant and 10 had other conditions making screening irrelevant, 166 patients were lost to view. Conclusion: Based on GPs' records, health insurance claim databases underestimate the number of screened women by 7.6%. The percentage of patients not responding to the invitation of their GP to be screened in the PaCUDAHL-Ge trial is 24.18%. Background: Over the past decade, the amount of digital data created by humans with or without connected tools has grown exponentially. The field of primary care (PC) did not escape this digitization, nor the use of Big Data algorithms. To evaluate the results of Big Data research in PC it seemed useful to identify which algorithms are used. Research question: What are the algorithms used for Big Data research in PC research and how are they described? Methods: Systematic review of the literature according to the recommendations of the PRISMA guide. A search equation using the following MeSH terms 'big data, data mining, Algorithms, Artificial Intelligence, Machine learning, Deep Learning, Neural Networks Natural Language Processing, general practice, electronic health records, health records' has been applied to the PUBMED database. After a selection of the titles and article summaries according to the inclusion criteria, the full versions of the eligible articles were read and analysed. Referenced articles of the sources articles were added to the analysis. The algorithms described in the articles were extracted and analysed. Results: In total, 778 articles were identified, 169 were eligible for full reading and 26 articles were finally selected. The algorithms listed in the articles are poorly described. The description is usually limited to a general explanation about how the algorithm works. Seven articles gave a partial description of the algorithm; a logic diagram was given in four articles and the codes in only two. Actually, only one article fully describes the algorithm with its mathematical description, its code and its logic diagram. Conclusion: Big Data algorithms in PC are not satisfactorily described. The lack of reproducibility is not compatible with a consistent scientific approach. Researchers should provide more information about the way they extract and analyse their data to give their readers more confidence in Big Data. Background: As a collaborative project of the Family Practice Depression and Multimorbidity group of European General Practice Research Network, the Hopkins Symptom Checklist-25 (HSCL-25) scale was identified as valid, reproducible, effective and easy to use. Subsequently, it has been translated and adapted to 13 languages, including Castilian. Currently, the scale is being validated in different languages. Research question: What are the psychometric properties of the Spanish version of HSCL-25 (HSCL-25e) for depression detection in Primary Care? Methods: HSCL-25e was administered to outpatients recruited by their physicians in six health centres involved in Spanish EIRA3 study, a trial to promote healthy behaviours in people aged from 45 to 75. Patients complimented HSCL-25 themselves. Sample size was calculated with R package (pROC). Statistical analysis: responsiveness was analysed with missing data and detecting ceiling and floor effects for the items. Principal component analysis (PCA) was done to determine the dimensions of HSCL-25e. Item-total correlation, Cronbach's alpha (global and dimensions coefficient) and squared multiple correlation were carried out to calculate internal consistency. Results: Seven hundred and sixty-nine patients out of 806 complimented HSCL-25e, 738 answered to all of the items. No patterns of missing answers were found. No ceiling effects, expected floor effect in item 18. Item 17 was the most consistent one and item 24 was the lower one. All items showed positive discrimination index for both cut-off points (1.55 and 1.75). PCA indicated two factors; 13 items corresponding to depression dimension and the other 12 items corresponding to anxiety subscale. Global Cronbach's alpha was 0.92 (0.88 calculated for depression dimension and 0.84 for anxiety dimension). Conclusion: The HSCL-25e has excellent psychometric properties when applied to Primary Care population. It has two dimensions as the original version, although the items included are not exactly the same. There are more item coincidences with the French version. Background: Cardiovascular diseases (CVDs) are the first mortality cause worldwide with 17.5 million death in 2012. Spices (Scaling-up Packages of Interventions for CVD prevention in selected sites in Europe and Sub-Saharan Africa) gathered five countries around CVD primary prevention interventions, especially for populations with low access to prevention and health care system. In France, a rural area where people were more deprived and with a low settlement of general practitioners (GPs) fitted with the project. Research question: What are the barriers and the facilitators for cardiovascular primary prevention implementation from caregivers and patients' point of view of a deprived rural area? Methods: Semi-structured interviews were conducted until theoretical saturation of data. Purposive samplings of GPs, patients, patients' families, nurses and pharmacists were designed. Five interview guides explored cardiovascular prevention, cardiovascular health promotion in the setting, actors of CVD prevention, capacities for CVD prevention, patients' and healthcare professionals' representations, barriers and facilitators in implementing CVD prevention, possible solutions. Guides were adapted concurrently to the analysis. A blinded thematic analysis and a mind-mapping were achieved for each group. Results: Thirteen GPS, 11 pharmacists', 14 nurses, 12 patients' and 12 patients' family members' interviews were achieved. Professionals highlighted a disconnection between them and national prevention programs, lack of time, payment and training for CVD prevention. Countryside was either protective or aggressive regarding CVD risk balancing gardening and space against isolation and lack of structures. GPs had poor connections with the community. Patients described their recklessness and feeling of invulnerability until their CVD appeared. Families could be a barrier to CVD prevention and lifestyle change. Risky behaviours were handed down from one generation to another. Conclusion: Innovative interventions for Spices should focus on these community specificities and individual behavioural strategies in contrast with the six national plans addressing CVD in France. These plans solely concentrate on dissemination of prevention messages and knowledge, which is of little use according to this survey. AN - WOS:000517857100001 DO - 10.1080/13814788.2020.1719994 IS - 1 N1 - [Anonymous] 1751-1402 PY - 2020 SN - 1381-4788 SP - 42-50 ST - General Practice and the Community: Research on health service, quality improvements and training. Selected abstracts from the EGPRN Meeting in Vigo, Spain, 17-20 October 2019 Abstracts T2 - European Journal of General Practice TI - General Practice and the Community: Research on health service, quality improvements and training. Selected abstracts from the EGPRN Meeting in Vigo, Spain, 17-20 October 2019 Abstracts UR - ://WOS:000517857100001 VL - 26 ID - 1861 ER - TY - JOUR AB - OBJECTIVE: The overall aim of this study was to determine the ability of 2 selected clinical tests to detect or predict neck pain, mid back pain, and low back pain in a school-based cohort of Danish 11- to 15-year-olds. METHODS: A school-based 2-year prospective cohort study was conducted. Data were collected at the age of 11 to 13 (n = 1224) and 2 years later (n = 963). Spinal pain (neck pain, mid back pain, and low back pain) was assessed by an electronic survey completed during school time, and reference standard was defined as both lifetime prevalence and frequent pain as a proxy of severity. The tests included assessments of scoliosis, hypermobility, global mobility, intersegmental mobility, end range pain, and isometric endurance of back extensors. Sensitivity, specificity, negative and positive predictive values, and odds ratios were calculated for each test individually, and area under the receiver operating characteristic curve was calculated for evaluation of all tests combined. RESULTS: The sensitivity was low, and specificity was high for all tests at both baseline (age, 11-13 years) and follow-up (age, 13-15 years). When all tests were evaluated collectively in 1 model, the area under the receiver operating characteristic curve ranged from 0.60 to 0.65. None of the selected tests could predict incidence cases of neck pain, mid back pain, or low back pain. CONCLUSION: Clinical tests commonly used in spinal screening in adolescents could not detect present spinal pain or predict future spinal pain. However, some statistically significant associations between spinal pain and tests involving a pain response from the participant were found. AU - Aartun, Ellen AU - Hartvigsen, Jan AU - Hestbaek, Lise DA - 2016/02// DO - 10.1016/j.jmpt.2016.01.007 DP - PubMed IS - 2 J2 - J Manipulative Physiol Ther KW - Adolescent Back Pain Denmark Diagnosis Female Humans Male Neck Pain Pain Measurement Physical Examination Predictive Value of Tests Prospective Studies Scoliosis Screening Sensitivity and Specificity Surveys and Questionnaires LA - eng PY - 2016 SN - 1532-6586 SP - 76-87 ST - Validity of Commonly Used Clinical Tests to Diagnose and Screen for Spinal Pain in Adolescents T2 - Journal of Manipulative and Physiological Therapeutics TI - Validity of Commonly Used Clinical Tests to Diagnose and Screen for Spinal Pain in Adolescents: A School-Based Cohort Study in 1300 Danes Aged 11-15 Years UR - http://www.ncbi.nlm.nih.gov/pubmed/26896035 VL - 39 ID - 93 ER - TY - JOUR AB - BACKGROUND: The severity and course of spinal pain is poorly understood in adolescents. The study aimed to determine the prevalence and two-year incidence, as well as the course, frequency, and intensity of pain in the neck, mid back, and low back (spinal pain). METHODS: This study was a school-based prospective cohort study. All 5th and 6th grade students (11-13 years) at 14 schools in the Region of Southern Denmark were invited to participate (N=1,348). Data were collected in 2010 and again two years later, using an e-survey completed during school time. RESULTS: The lifetime prevalence of spinal pain was 86% and 89% at baseline and follow-up, respectively. A group of 13.6% (95% CI: 11.8, 15.6) at baseline and 19.5% (95% CI: 17.1, 22.0) at follow-up reported that they had pain frequently. The frequency of pain was strongly associated with the intensity of pain, i.e., the majority of the participants reported their pain as relatively infrequent and of low intensity, whereas the participants with frequent pain also experienced pain of higher intensity. The two-year incidence of spinal pain varied between 40% and 60% across the physical locations. Progression of pain from one to more locations and from infrequent to more frequent was common over the two-year period. CONCLUSIONS: Spinal pain is common at the age of 11-15 years, but some have more pain than others. The pain is likely to progress, i.e., to more locations, higher frequency, and higher pain intensity over a two-year period. AU - Aartun, Ellen AU - Hartvigsen, Jan AU - Wedderkopp, Niels AU - Hestbaek, Lise DA - 2014/05/29/ DO - 10.1186/1471-2474-15-187 DP - PubMed J2 - BMC Musculoskelet Disord KW - Adolescent Back Pain Child Cluster Analysis Cohort Studies Denmark Female Follow-Up Studies Humans Incidence Longitudinal Studies Male Neck Pain Pain Measurement Prevalence Prospective Studies School Health Services Students LA - eng PY - 2014 SN - 1471-2474 SP - 187 ST - Spinal pain in adolescents T2 - BMC musculoskeletal disorders TI - Spinal pain in adolescents: prevalence, incidence, and course: a school-based two-year prospective cohort study in 1,300 Danes aged 11-13 UR - http://www.ncbi.nlm.nih.gov/pubmed/24885549 VL - 15 ID - 86 ER - TY - JOUR AB - Background This review supersedes the original Cochrane review first published in 2008 (Huertas-Ceballos 2008). Between 4% and 25% of school-aged children complain of recurrent abdominal pain (RAP) severe enough to interfere with their daily activities. No organic cause for this pain can be found on physical examination or investigation for the majority of such children. Althoughmany children aremanaged by reassurance and simplemeasures, a large range of psychosocial interventions involving cognitive and behavioural components have been recommended. Objectives To determine the effectiveness of psychosocial interventions for reducing pain in school-aged children with RAP. Search methods In June 2016 we searched CENTRAL, MEDLINE, Embase, eight other databases, and two trials registers. We also searched the references of identified studies and relevant reviews. Selection criteria Randomised controlled trials comparing psychosocial therapies with usual care, active control, or wait-list control for children and adolescents (aged 5 to 18 years) with RAP or an abdominal pain-related functional gastrointestinal disorder defined by the Rome III criteria were eligible for inclusion. Data collection and analysis We used standard methodological procedures expected by Cochrane. Five review authors independently selected studies, assessed them for risk of bias, and extracted relevant data. We also assessed the quality of the evidence using the GRADE approach. Main results This review includes 18 randomised controlled trials (14 new to this version), reported in 26 papers, involving 928 children and adolescents with RAP between the ages of 6 and 18 years. The interventions were classified into four types of psychosocial therapy: cognitive behavioural therapy (CBT), hypnotherapy (including guided imagery), yoga, and written self-disclosure. The studies were carried out in the USA, Australia, Canada, the Netherlands, Germany, and Brazil. The majority of the studies were small and short term; only two studies included more than 100 participants, and only five studies had follow-up assessments beyond six months. Small sample sizes and the degree of assessed risk of performance and detection bias in many studies led to the overall quality of the evidence being rated as low to very low for all outcomes. For CBT compared to control, we found evidence of treatment success postintervention (odds ratio (OR) 5.67, 95% confidence interval (CI) 1.18 to 27.32; Z = 2.16; P = 0.03; 4 studies; 175 children; very low-quality evidence), but no evidence of treatment success at medium-term follow-up (OR 3.08, 95% CI 0.93 to 10.16; Z = 1.85; P = 0.06; 3 studies; 139 children; low-quality evidence) or longterm follow-up (OR 1.29, 95% CI 0.50 to 3.33; Z = 0.53; P = 0.60; 2 studies; 120 children; low-quality evidence). We found no evidence of effects of intervention on pain intensity scores measured postintervention (standardised mean difference (SMD) -0.33, 95% CI -0.74 to 0.08; 7 studies; 405 children; low-quality evidence), or at medium-term follow-up (SMD -0.32, 95% CI -0.85 to 0.20; 4 studies; 301 children; low-quality evidence). For hypnotherapy (including studies of guided imagery) compared to control, we found evidence of greater treatment success postintervention (OR 6.78, 95% CI 2.41 to 19.07; Z = 3.63; P = 0.0003; 4 studies; 146 children; low-quality evidence) as well as reductions in pain intensity (SMD -1.01, 95% CI -1.41 to -0.61; Z = 4.97; P < 0.00001; 4 studies; 146 children; low-quality evidence) and pain frequency (SMD -1.28, 95% CI -1.84 to -0.72; Z = 4.48; P < 0.00001; 4 studies; 146 children; low-quality evidence). The only study of long-term effect reported continued benefit of hypnotherapy compared to usual care after five years, with 68% reporting treatment success compared to 20% of controls (P = 0.005). For yoga therapy compared to control, we found no evidence of effectiveness on pain intensity reduction postintervention (SMD 0.31, 95% CI -0.67 to 0.05; Z = 1.69; P = 0.09; 3 studies; 122 children; low-quality evidence). The single study of written self-disclosure therapy reported no benefit for pain. There was no evidence of effect fromthe pooled analyses for any type of intervention on the secondary outcomes of school performance, social or psychological functioning, and quality of daily life. There were no adverse effects for any of the interventions reported. Authors' conclusions The data from trials to date provide some evidence for beneficial effects of CBT and hypnotherapy in reducing pain in the short term in children and adolescents presenting with RAP. There was no evidence for the effectiveness of yoga therapy or written self-disclosure therapy. There were insufficient data to explore effects of treatment by RAP subtype. Higher-quality, longer-duration trials are needed to fully investigate the effectiveness of psychosocial interventions. Identifying the active components of the interventions and establishing whether benefits are sustained in the long term are areas of priority. Future research studies would benefit from employing active control groups to help minimise potential bias from wait-list control designs and to help account for therapist and intervention time. AN - WOS:000396096100016 AU - Abbott, R. A. AU - Martin, A. E. AU - Newlove-Delgado, T. V. AU - Bethel, A. AU - Thompson-Coon, J. AU - Whear, R. AU - Logan, S. C7 - Cd010971 DO - 10.1002/14651858.CD010971.pub2 IS - 1 N1 - Abbott, Rebecca A. Martin, Alice E. Newlove-Delgado, Tamsin V. Bethel, Alison Thompson-Coon, Joanna Whear, Rebecca Logan, Stuart Coon, Jo Thompson/C-7923-2017 Coon, Jo Thompson/0000-0002-5161-0234; Logan, Stuart/0000-0002-9279-261X; Abbott, Rebecca/0000-0003-4165-4484; Whear, Rebecca/0000-0002-8379-8198 1361-6137 PY - 2017 SN - 1469-493X ST - Psychosocial interventions for recurrent abdominal pain in childhood T2 - Cochrane Database of Systematic Reviews TI - Psychosocial interventions for recurrent abdominal pain in childhood UR - ://WOS:000396096100016 ID - 2113 ER - TY - JOUR AB - Secondary school Saudi students participated in a questionnaire about stomatognathic dysfunction symptoms. The adolescents were interviewed about general health, peripheral joint disease, chewing function, oral parafunctions, and symptoms of dysfunction. Thirty-two per cent of participants had at least one dysfunction symptom. Pain on opening was the most common (35.7%), followed by headache (33.6%), and joint sounds (32.2%). Symptoms increased with decline in general health, particularly the health of peripheral joints. Chewing functions were not impaired. Tooth loss did not affect dysfunction symptoms in adolescents, whilst a weak relation was evident between oral parafunctions and symptoms of mandibular dysfunction. AD - College of Dentistry, King Saud University, Riyadh, Kingdom of Saudi Arabia. AN - 8933381 AU - Abdel-Hakim, A. M. AU - Alsalem, A. AU - Khan, N. DA - Oct DO - 10.1046/j.1365-2842.1996.d01-181.x DP - NLM ET - 1996/10/01 IS - 10 KW - Adolescent Adult Facial Pain/epidemiology Female Habits Headache/epidemiology Health Status Humans Male Mastication Prevalence Range of Motion, Articular Saudi Arabia/epidemiology Temporomandibular Joint Dysfunction Syndrome/*epidemiology Tooth Loss/epidemiology LA - eng N1 - Abdel-Hakim, A M Alsalem, A Khan, N Journal Article England J Oral Rehabil. 1996 Oct;23(10):655-61. doi: 10.1046/j.1365-2842.1996.d01-181.x. PY - 1996 SN - 0305-182X (Print) 0305-182x SP - 655-61 ST - Stomatognathic dysfunctional symptoms in Saudi Arabian adolescents T2 - J Oral Rehabil TI - Stomatognathic dysfunctional symptoms in Saudi Arabian adolescents VL - 23 ID - 3710 ER - TY - JOUR AB - Management of sickle cell pain in adolescent and pediatric patients is inadequate, and the employment of proper management guidelines and practices are highly variable among different regions and populations. APPT, the multidimensional adolescent pediatric pain tool, promotes optimal pain management and introduces best practical guidelines for pain management. The goal of this study is to assess pain and pain management among young patients diagnosed with sickle cell disease (SCD) by introducing the APPT as a tool for pain management, and analyze factors contributing to pain management. Information relevant to demographic data, SCD characteristics, APPT assessment, and satisfaction of patients regarding pain management were collected using a structured questionnaire. Results showed that SCD is highly associated with gender (p = 0.022), consanguinity (p = 0.012), and number of surgeries (p = 0.013). Most patients (58.9%) indicated the involvement of more than six body areas affected during pain crisis. Severe pain was described by more than half the patients (55.6%), while moderate pain was reported by 31.1%. Most patients described their pain by sensory, affective, and temporal words. The number of painful areas, pain intensity, and use of descriptive pain words was correlated and interpreted by age, BMI, school absence, and number of surgeries. Results of this study could provide guidance to healthcare providers to improve current practices for SCD pain management in order to improve health outcomes and patients' satisfaction. AN - WOS:000482974100003 AU - Abdo, S. AU - Nuseir, K. Q. AU - Altarifi, A. A. AU - Barqawi, M. AU - Ayoub, N. M. AU - Mukkatash, T. L. C7 - 182 DA - Aug DO - 10.3390/brainsci9080182 IS - 8 N1 - Abdo, Samar Nuseir, Khawla Q. Altarifi, Ahmad A. Barqawi, Moussa Ayoub, Nehad M. Mukkatash, Tareq L. Nuseir, Khawla/X-9686-2019; Mukattash, Tareq/AAN-2732-2020 Nuseir, Khawla/0000-0002-1696-247X; , Ahmad/0000-0001-9574-8422; Mukattash, Tareq/0000-0003-0200-9845 2076-3425 PY - 2019 ST - Management of Sickle Cell Disease Pain among Adolescent and Pediatric Patients T2 - Brain Sciences TI - Management of Sickle Cell Disease Pain among Adolescent and Pediatric Patients UR - ://WOS:000482974100003 VL - 9 ID - 1892 ER - TY - JOUR AB - The aim of this study was to investigate the factors associated with school absenteeism and poor school functioning in Egyptian children and adolescents with juvenile idiopathic arthritis (JIA). We studied 52 consecutive patients of JIA with age a parts per thousand yen7 years and duration of disease a parts per thousand yen1 year. All of the patients underwent assessment of socioeconomic and demographic characteristics, disease activity (JIDAS-27), functional ability (CHAQ), depressive symptoms (CDI score), and school functioning (PedsQL (TM) 4.0). Multivariate modeling was applied to determine the factors that associated with school absenteeism and poor school functioning. A total of 69 % of the sample missed 3 weeks or more of school during past academic year. The mean percentage of missed school days was 12.5 % (equivalent to 25 absent days). A total of 46 % of the patients had poor school functioning (school functioning subscale score of HRQOL a parts per thousand yen1 SD below the mean of healthy children). In multiple regression analyses, high CHAQ scores, disease activity, and depressive symptoms were independent predictors for both of school absenteeism and of poor school functioning. However, living in rural regions was independently associated only with high school absenteeism in patients with JIA. Disease activity, functional disability, and high depressive symptoms are predictors of school absenteeism and poor school functioning. These findings underscore the critical need for treatment strategies that have the ability to better control disease activity, to minimize functional disability, and depressive symptoms. More attention should be given to JIA patients who live in rural regions. AN - WOS:000329324600004 AU - Abdul-sattar, A. AU - Abou El Magd, S. AU - Negm, M. G. DA - Jan DO - 10.1007/s00296-013-2871-4 IS - 1 N1 - Abdul-sattar, Amal Abou El Magd, Sahar Negm, Mohamed G. Sattar, Amal Bakry Abdul/H-3360-2019 1437-160x PY - 2014 SN - 0172-8172 SP - 35-42 ST - Associates of school impairment in Egyptian patients with juvenile idiopathic arthritis: Sharkia Governorate T2 - Rheumatology International TI - Associates of school impairment in Egyptian patients with juvenile idiopathic arthritis: Sharkia Governorate UR - ://WOS:000329324600004 VL - 34 ID - 2327 ER - TY - JOUR AB - The aim of this study was to identify the possible determinants of impaired health-related quality of life (HRQOL) in Egyptian children and adolescents with juvenile idiopathic arthritis (JIA). Fifty-eight consecutive patients of JIA aged from 8 to 18 years underwent assessment of socio-economic and demographic characteristics; HRQOL using Pediatric Quality of Life Inventory 4.0 Generic Core Scale, disease activity using the Juvenile Arthritis Disease Activity Score based on 27 joints (JADAS-27), functional ability using the childhood health assessment questionnaire (CHAQ), pain score on visual analog scale and psychological symptoms using the Children's Depression Inventory (CDI) score. Multivariate modeling was applied to determine the factors that associated with HRQOL impairment. A total of 55 % of the patients (32 of 58) had impaired HRQOL (<78.6). In multiple regression analyses, high CHAQ scores (OR 6.0, 95 % CI 2.0-17.5, P = 0.001), pain (OR 3.1, 95 % CI 1.9-6.3, P = 0.01), stop going to school (OR 3.9, 95 % CI 2.0-7.3, P = 0.01), low socioeconomic status (OR 2.3, 95 % CI 1.09-4.7, P = 0.04) and high psychological symptoms (OR 4.2, 95 % CI 2.0-12.6, P = 0.001) were determinants for HRQOL impairment. HRQOL impairment is a significant problem in Egyptian children and adolescents with JIA. These findings underscore the critical need for monitoring of HRQOL in these patients. More attention should be given to JIA patients who stop going to school and who has low socioeconomic status. AN - WOS:000339725500009 AU - Abdul-Sattar, A. B. AU - Elewa, E. A. AU - El-Shahawy, E. E. AU - Waly, E. H. DA - Aug DO - 10.1007/s00296-014-2950-1 IS - 8 N1 - Abdul-Sattar, Amal B. Elewa, Enass A. El-Shahawy, Eman El-Dessoky Waly, Eman H. Sattar, Amal Bakry Abdul/H-3360-2019 1437-160x PY - 2014 SN - 0172-8172 SP - 1095-1101 ST - Determinants of health-related quality of life impairment in Egyptian children and adolescents with juvenile idiopathic arthritis: Sharkia Governorate T2 - Rheumatology International TI - Determinants of health-related quality of life impairment in Egyptian children and adolescents with juvenile idiopathic arthritis: Sharkia Governorate UR - ://WOS:000339725500009 VL - 34 ID - 2296 ER - TY - JOUR AB - STUDY DESIGN: A cohort of 1848 workers, representative of all sectors of industry, who were compensated for a low back injury in 1988 but not in the previous 2 years, was followed over 24 months. OBJECTIVES: To determine the prognostic value of the physician's initial diagnosis of back problems. SUMMARY OF BACKGROUND DATA: In the absence of a standardized classification of diagnoses of back pain, this study aimed to provide an element of validity to a classification previously proposed that consists of "specific" and "nonspecific" back pain. METHODS: Medical charts were reviewed at the Quebec Worker's Compensation Board to extract the diagnosis made by the treating physicians within 7 days of the first day of absence from work. Diagnoses were categorized into "specific" (lesions of vertebrae and discs) and "nonspecific" (pain, sprains, and strains). The history of compensated work absence for low back pain in the following 24 months was obtained. RESULTS: A specific diagnosis was found in 8.9% (165) of the workers, accounting for 31.0% of the patients who accumulated 6 months or more of absence in 2 years. Increasing age and daily amount of compensation also were associated with an increased risk of chronicity. CONCLUSIONS: The physician's initial diagnosis was highly associated with the risk of chronicity. The explanation for this result is complex, involving the nature of the underlying lesion as well as the impact of the diagnosis "label" on the worker and on the physician-patient relationship. AD - Centre for Clinical Epidemiology and Community Studies, Sir Mortimer B. Davis Jewish General Hospital, Montreal, Quebec, Canada. AN - 7701392 AU - Abenhaim, L. AU - Rossignol, M. AU - Gobeille, D. AU - Bonvalot, Y. AU - Fines, P. AU - Scott, S. DA - Apr 1 DO - 10.1097/00007632-199504000-00010 DP - NLM ET - 1995/04/01 IS - 7 KW - Absenteeism *Accidents, Occupational Adolescent Adult *Back Injuries Back Pain/economics/*epidemiology/etiology Chronic Disease Cohort Studies Female Follow-Up Studies Humans Incidence Male Medical Records Middle Aged Prevalence Prognosis Quebec/epidemiology Time Factors *Workers' Compensation LA - eng N1 - Abenhaim, L Rossignol, M Gobeille, D Bonvalot, Y Fines, P Scott, S Journal Article Research Support, Non-U.S. Gov't United States Spine (Phila Pa 1976). 1995 Apr 1;20(7):791-5. doi: 10.1097/00007632-199504000-00010. PY - 1995 SN - 0362-2436 (Print) 0362-2436 SP - 791-5 ST - The prognostic consequences in the making of the initial medical diagnosis of work-related back injuries T2 - Spine (Phila Pa 1976) TI - The prognostic consequences in the making of the initial medical diagnosis of work-related back injuries VL - 20 ID - 3444 ER - TY - JOUR AB - OBJECTIVE: To study the clinical and epidemiological characteristics of complex regional pain syndrome (CRPS) in children. PATIENTS AND METHODS: All children and adolescents under 16 years of age with a new diagnosis of CRPS who were reported to the Scottish Paediatric Surveillance Unit were included. Patients' recruitment ran between 1 November 2011 and 31 October 2015. Information was collected on patients' demography, clinical features, investigations, management and impact of disease on child and family. The diagnosis of CRPS was made on fulfilling the clinical criteria of the International Association for the Study of Pain. RESULTS: 26 cases of CRPS were reported over 4 years, giving a minimum estimated incidence of 1.16/100 000 (95% CI 0.87 to 1.44/100 000) children 5-15 years of age. Nineteen patients were female (73%) and mean age at diagnosis was 11.9 (range 5.5-15.4 years). The median interval between onset of symptoms and diagnosis was 2 months (range 1-12). The majority of children have single site involvement, with legs been more often affected than arms and the right side is more often affected than the left. There was a clear trauma at onset of the illness in 19 children and possible nerve injury in one. All investigations were normal and several treatment modalities were used with variable success. The disease had significant impacts on the patients' education and family lives. CONCLUSIONS: The estimated incidence of CRPS is 1.2/100 000 children 5-15 years old. The diagnosis of CRPS is often delayed. CRPS has a significant impact on children and their families. AD - University of Edinburgh, Edinburgh, UK Department of Paediatrics, Forth Valley Royal Hospital, Larbert, Stirlingshire, UK. Department of Paediatrics, Forth Valley Royal Hospital, Larbert, Stirlingshire, UK. AN - 27005945 AU - Abu-Arafeh, H. AU - Abu-Arafeh, I. DA - Aug DO - 10.1136/archdischild-2015-310233 DP - NLM ET - 2016/03/24 IS - 8 KW - Absenteeism Adolescent Age Distribution Age of Onset Analgesics/therapeutic use Child Child, Preschool Complex Regional Pain Syndromes/diagnosis/*therapy Female Humans Leisure Activities Magnetic Resonance Imaging Male Nerve Block/methods Prospective Studies Quality of Life Radiography Sex Distribution Ultrasonography, Doppler *Adolescents *Causalgia *Complex Regional Pain Syndrome *Incidence *Reflex Sympathetic Dystrophy LA - eng N1 - 1468-2044 Abu-Arafeh, Hashem Abu-Arafeh, Ishaq Journal Article Observational Study England Arch Dis Child. 2016 Aug;101(8):719-23. doi: 10.1136/archdischild-2015-310233. Epub 2016 Mar 22. PY - 2016 SN - 0003-9888 SP - 719-23 ST - Complex regional pain syndrome in children: incidence and clinical characteristics T2 - Arch Dis Child TI - Complex regional pain syndrome in children: incidence and clinical characteristics VL - 101 ID - 3040 ER - TY - JOUR AB - The prevalence and clinical features of migraine headache and abdominal migraine were studied in the well defined population of Aberdeen schoolchildren. Ten per cent of all children (2165) aged 5-15 years were given a questionnaire inquiring, among other symptoms, about the history of headache and abdominal pain over the past year. A total of 1754 children (81%) responded. Children with at least two episodes of severe headache and/or severe abdominal pain, attributed by the parents either to unknown causes or to migraine, were invited to attend for clinical interview and examination. After interview, 159 children fulfilled the International Headache Society's criteria for the diagnosis of migraine and 58 children had abdominal migraine giving estimated prevalence rates of 10.6% and 4.1% respectively. Children with abdominal migraine had demographic and social characteristics similar to those of children with migraine. They also had similar patterns of associated recurrent painful conditions, trigger and relieving factors, and associated symptoms during attacks. The similarities between the two conditions are so close as to suggest that they have a common pathogenesis. AN - WOS:A1995QZ45900010 AU - Abuarafeh, I. AU - Russell, G. DA - May DO - 10.1136/adc.72.5.413 IS - 5 N1 - Abuarafeh, i russell, g Abu-Arafeh, Ishaq/H-7417-2019 Abu-Arafeh, Ishaq/0000-0003-1252-0153 PY - 1995 SN - 0003-9888 SP - 413-417 ST - PREVALENCE AND CLINICAL-FEATURES OF ABDOMINAL MIGRAINE COMPARED WITH THOSE OF MIGRAINE HEADACHE T2 - Archives of Disease in Childhood TI - PREVALENCE AND CLINICAL-FEATURES OF ABDOMINAL MIGRAINE COMPARED WITH THOSE OF MIGRAINE HEADACHE UR - ://WOS:A1995QZ45900010 VL - 72 ID - 2937 ER - TY - JOUR AB - Objectives-To determine the prevalence rates of the various causes of severe headache in school-children, with special emphasis on migraine and its impact on school attendance. Design-Population based study in two stages, comprising an initial screening questionnaire followed by clinical interviews and examination of children with symptoms and a control group of asymptomatic children matched for age and sex. Setting-67 primary and secondary schools in the city of Aberdeen. Subjects-2165 children, representing a random sample of 10% of schoolchildren in Aberdeen aged 5-15 years. Main outcome measures-(a) the prevalence of migraine (International Headache Society criteria) and of other types of headache; (b) the impact of migraine on school attendance. Results-The estimated prevalence rates of migraine and tension headache were 10.6% (95% confidence interval 9.1 to 12.3) and 0.9% (0.5 to 1.5) respectively. The estimated prevalence rates for migraine without aura and migraine with aura were 7.8% (95% confidence interval 6.5 to 9.3) and 2.8% (2.0 to 3.8) respectively. In addition, 10 children (0.7%) had headaches which, though lasting less than two hours, also fulfilled the International Headache Society criteria for migraine, 14 (0.9%) had tension headaches, and 20 (1.3%) had non-specific recurrent headache. The prevalence of migraine increased with age, with male preponderance in children under 12 and female preponderance thereafter. Children with migraine lost a mean of 7.8 school days a year due to all illnesses (2.8 days (range 0-80) due to headache) as compared with a mean of 3.7 days lost by controls. Conclusions-Migraine is a common cause of headache in children and causes significantly reduced school attendance. AN - WOS:A1994PJ28200016 AU - Abuarefeh, I. AU - Russell, G. DA - Sep DO - 10.1136/bmj.309.6957.765 IS - 6957 N1 - Abuarefeh, i russell, g Abu-Arafeh, Ishaq/H-7417-2019; Fahimifar, Sepideh/M-5303-2019 Abu-Arafeh, Ishaq/0000-0003-1252-0153; PY - 1994 SN - 0959-8138 SP - 765-769 ST - PREVALENCE OF HEADACHE AND MIGRAINE IN SCHOOLCHILDREN T2 - British Medical Journal TI - PREVALENCE OF HEADACHE AND MIGRAINE IN SCHOOLCHILDREN UR - ://WOS:A1994PJ28200016 VL - 309 ID - 2946 ER - TY - JOUR AB - Introduction: Migraine attacks associated with menstruation are generally perceived as more severe than attacks outside this period. Aim and Objective: The study aimed at determining the frequency of menstrual-related headaches among a cohort of senior secondary school girls in Abeokuta, Nigeria. We also determined its burden among these school girls. Methodology: This study was cross-sectional using a validated adolescent headache survey questionnaire. A self-administration of the instrument was done during a school visit. A headache was classified using the ICHD-II criteria. Results: Of the 183 students interviewed, 123(67.2%) had recurrent headaches. Mean age +SD, 16.18+1.55 (range 12-19). The prevalence of definite migraine was 17.5% while the prevalence of probable migraine was 6.0%. The prevalence of tension-type headache was 41.0%. Migraine was significantly menstrual-related (p=0.001, 95% CI=1.06-6.63). Median pain severity score was higher among MRH group (p=0.043). The median number of days of reduced productivity and missed social activities was significantly higher in the MRH group; p= 0.001 and p=0.03, respectively. Subjects with MRH were more incapacitated by their headaches (p= 0.003). Conclusion: Menstrually related headache is prevalent even among the adolescent and it has adversely affected their productivity and social life. Care of adolescent with headaches should be intensified. AN - WOS:000510692800001 AU - Adebayo, P. B. AU - Otubogun, F. M. AU - Akinyemi, R. O. DO - 10.2147/jpr.S207620 N1 - Adebayo, Philip B. Otubogun, Folajimi M. Akinyemi, Rufus O. Adebayo, Philip/ABE-1191-2020 Akinyemi, Rufus/0000-0001-5286-428X PY - 2020 SN - 1178-7090 SP - 143-150 ST - Menstrual-Related Headaches Among a Cohort of African Adolescent Girls T2 - Journal of Pain Research TI - Menstrual-Related Headaches Among a Cohort of African Adolescent Girls UR - ://WOS:000510692800001 VL - 13 ID - 1862 ER - TY - JOUR AB - BACKGROUND: Adolescent low back pain (ALBP) can be considered a signal or precursor of a serious organic disease or telltale sign of future incidence of low back pain in adulthood. Published articles on ALBP in Nigeria are not readily available. OBJECTIVES: The study's objectives were to investigate the prevalence of Adolescent Low Back Pain (ALBP) among secondary school students in Ibadan, Nigeria and the prevalence's association with some socio-demographic variables. METHODS: Participants were adolescent students from 15 secondary schools in Ibadan. Data was collected using a respondent-administered, validated questionnaire on low back pain in adolescents. Participants (Female: 298; Male: 273) aged 14.23 ±2.27 years (range 10-19) were recruited through multi-stage random sampling. Five hundred and seventy-one (83.97%) of the 680 copies of the questionnaire administered were returned. Data was analysed using mean, standard deviation, frequency, percentages, and Chi-square test with alpha level at 0.05. RESULT: Lifetime, twelve-month, one-month and point prevalence rates of ALBP were 58.0%, 43.8%, 25.6% and 14.7% respectively. Age at first experience of ALBP was 11.86 ± 2.36 years. Gender was not significantly associated with any rate (p ≥0.317). Age (p ≤ 0.043) and engagement in commercial activities (p ≤ 0.025) were significantly associated with all period prevalence rates while injury to the back was significantly associated with all period prevalence rates except point prevalence (p = 0.087). CONCLUSION: Adolescent low back pain is common among secondary school students in Ibadan and its prevalence is significantly associated with age and engagement in commercial activities, but not with gender. AU - Adegoke, Babatunde O. A. AU - Odole, Adesola C. AU - Adeyinka, Adebayo A. DA - 2015/06// DO - 10.4314/ahs.v15i2.16 DP - PubMed IS - 2 J2 - Afr Health Sci KW - Adolescent Age Distribution Age Factors Body Mass Index Cross-Sectional Studies Female Humans low back pain Male Nigeria Pain Measurement Prevalence Risk Factors school children Schools Sex Distribution Sex Factors Sickness Impact Profile Students Surveys and Questionnaires LA - eng PY - 2015 SN - 1729-0503 SP - 429-437 ST - Adolescent low back pain among secondary school students in Ibadan, Nigeria T2 - African Health Sciences TI - Adolescent low back pain among secondary school students in Ibadan, Nigeria UR - http://www.ncbi.nlm.nih.gov/pubmed/26124788 VL - 15 ID - 80 ER - TY - JOUR AB - INTRODUCTION: irritable bowel syndrome (IBS) is one of the functional gastrointestinal disorders (FGIDs) which has been well described in western populations especially as the commonest cause of recurrent abdominal pain The aim of this study was to document the prevalence of Irritable bowel syndrome (IBS) amongst children in western Nigeria and increase the aware ness of IBS amongst physicians who manage children with abdominal pain. METHODS: This was a cross-sectional study conducted amongst children aged 10-18 years in 8 schools located in two local government areas of Lagos state. A multistage stratified random-sampling survey was conducted using the validated Rome III criteria to assess for IBS and associated risk factors. The subtypes of IBS and associated extra-intestinal symptoms were also documented. RESULTS: The prevalence of IBS was 16.0% in the study participants and the prevalence decreased with increasing age (p=0.05). Sixty two (62.5%) of the students with recurrent abdominal pain had IBS. IBS was more prevalent in the females compared to the males (p=0.000). The significant risk factors for IBS identified were gender (p=0.000), socioeconomic status (p=0.001) and past history of gastroenteritis (p=0.011). The commonest subtype of IBS seen was the alternating subtype. CONCLUSION: IBS is prevalent in African children. Physicians who attend to children need to have a high index of suspicion for IBS in children who present with abdominal pain when there are no alarm symptoms. The need for further longitudinal studies in African children cannot be overemphasized. AD - Department of Paediatrics, College of Medicine, University of Lagos,Lagos University Teaching Hospital, Idi-Araba, Lagos, Nigeria. Department of Medicine, College of Medicine, University of Lagos, Lagos University Teaching Hospital, Idi-Araba, Lagos, Nigeria. Department of Community Health, College of Medicine, University of Lagos, Idi-Araba, Lagos, Nigeria. Department of Paediatrics, University of Calabar Teaching Hospital, Calabar, Cross River State, Nigeria. AN - 29255563 AU - Adeniyi, O. F. AU - Adenike Lesi, O. AU - Olatona, F. A. AU - Esezobor, C. I. AU - Ikobah, J. M. C2 - PMC5724937 DO - 10.11604/pamj.2017.28.93.11512 DP - NLM ET - 2017/12/20 KW - Abdominal Pain/*etiology Adolescent Age Factors Child Cross-Sectional Studies Female Gastroenteritis/*epidemiology Humans Irritable Bowel Syndrome/*epidemiology Male Nigeria/epidemiology Prevalence Risk Factors Sex Factors Socioeconomic Factors Irritable bowel syndrome adolescents subtypes LA - eng N1 - 1937-8688 Adeniyi, Oluwafunmilayo Funke Adenike Lesi, Olufunmilayo Olatona, Foluke Adenike Esezobor, Christoper Imokhuede Ikobah, Joanah Moses Journal Article Multicenter Study Pan Afr Med J. 2017 Sep 29;28:93. doi: 10.11604/pamj.2017.28.93.11512. eCollection 2017. PY - 2017 SP - 93 ST - Irritable bowel syndrome in adolescents in Lagos T2 - Pan Afr Med J TI - Irritable bowel syndrome in adolescents in Lagos VL - 28 ID - 3844 ER - TY - JOUR AB - Objectives. Joint hypermobility (JH) or 'ligamentous laxity' is felt to be an underlying risk factor for many types of musculoskeletal presentation in paediatrics, and joint hypermobility syndrome (JHS) describes such disorders where symptoms become chronic, often more generalized and associated with functional impairment. Clinical features are felt to have much in common with more severe disorders, including Ehlers-Danlos syndrome (EDS), osteogenesis imperfecta and Marfan syndrome, although this has not been formally studied in children. We defined the clinical characteristics of all patients with joint hypermobility-related presentations seen from 1999 to 2002 in a tertiary referral paediatric rheumatology unit. Methods. Patients were identified and recruited from paediatric rheumatology clinic and ward, and a dedicated paediatric rheumatology hypermobility clinic at Great Ormond Street Hospital. Data were collected retrospectively on the patients from the paediatric rheumatology clinics (1999-2002) and prospectively on patients seen in the hypermobility clinic (2000-2002). Specifically, historical details of developmental milestones, musculoskeletal or soft tissue diagnoses and symptoms, and significant past medical history were recorded. Examination features sought included measurements of joint and soft tissue laxity, and associated conditions such as scoliosis, dysmorphic features, cardiac murmurs and eye problems. Results. One hundred and twenty-five children (64 females) were included on whom sufficient clinical data could be identified and who had clinical problems ascribed to JH present for longer than 3 months. Sixty-four were from the paediatric rheumatology clinic and 61 from the hypermobility clinic. No differences were found in any of the measures between the two populations and results are presented in a combined fashion. Three-quarters of referrals came from paediatricians and general practitioners but in only 10% was hypermobility recognized as a possible cause of joint complaint. The average age at onset of symptoms was 6.2 yr and age at diagnosis 9.0 yr, indicating a 2- to 3-yr delay in diagnosis. The major presenting complaint was arthralgia in 74%, abnormal gait in 10%, apparent joint deformity in 10% and back pain in 6%. Mean age at first walking was 15.0 months; 48% were considered 'clumsy' and 36% as having poor coordination in early childhood. Twelve per cent had 'clicky' hips at birth and 4% actual congenital dislocatable hip. Urinary tract infections were present in 13 and 6% of the female and male cases, respectively. Thirteen and 14%, respectively, had speech and learning difficulties diagnosed. A history of recurrent joint sprains was seen in 20% and actual subluxation/dislocation of joints in 10%. Forty per cent had experienced problems with handwriting tasks, 48% had major limitations of school-based physical education activities, 67% other physical activities and 41% had missed significant periods of schooling because of symptoms. Forty-three per cent described a history of easy bruising. Examination revealed that 94% scored >= 4/9 on the Beighton scale for generalized hypermobility, with knees (92%), elbows (87%), wrists (82%), hand metacarpophalangeal joints (79%), and ankles (75%) being most frequently involved. Conclusions. JHS is poorly recognized in children with a long delay in the time to diagnosis. Although there is a referral bias towards joint symptoms, a surprisingly large proportion is associated with significant neuromuscular and motor development problems. Our patients with JHS also show many overlap features with genetic disorders such as EDS and Marfan syndrome. The delay in diagnosis results in poor control of pain and disruption of normal home life, schooling and physical activities. Knowledge of the diagnosis and simple interventions are likely to be highly effective in reducing the morbidity and cost to the health and social services. AN - WOS:000229441400008 AU - Adib, N. AU - Davies, K. AU - Grahame, R. AU - Woo, P. AU - Murray, K. J. DA - Jun DO - 10.1093/rheumatology/keh557 IS - 6 N1 - Adib, N Davies, K Grahame, R Woo, P Murray, KJ PY - 2005 SN - 1462-0324 SP - 744-750 ST - Joint hypermobility syndrome in childhood. A not so benign multisystem disorder? T2 - Rheumatology TI - Joint hypermobility syndrome in childhood. A not so benign multisystem disorder? UR - ://WOS:000229441400008 VL - 44 ID - 2763 ER - TY - JOUR AB - Temporomandibular disorders and orofacial pain (TMD/OFP) conditions are challenging to diagnose for predoctoral dental students due to the multifactorial etiology, complexity, and controversial issues surrounding these conditions. The aim of this study was to determine if patients in the clinic of one U.S. dental school reported existing signs and symptoms of TMD/OFP, whether the dental students diagnosed the condition based on the reported signs and symptoms, and if the condition was then treated. The study was based on a retrospective analysis of electronic health record data over a three-year period. The results showed that, during the study period, 21,352 patients were treated by student providers. Of those patients, 5.33% reported signs or symptoms associated with TMD/OFP; 5.99% received a TMD/OFP diagnosis; and 0.26% received at least one form of TMD/OFP treatment that had either a diagnosis or signs/symptoms of TMD/OFP. In addition, a small percentage (0.24%) of patients with no documented diagnosis received some sort of TMD/OFP-related treatment. A randomly selected sample of 90 patient charts found that no diagnoses of TMD/OFP were recorded in any of them. The results suggested that students had only marginally diagnosed the problems. Training for students including comprehensive didactic courses and clinical experiences to gain knowledge, context, and skill may be required to ensure they reach the required level of competence and prepare them to face the diagnostic challenges of TMD/OFP after graduation. AD - Dr. Adibi is Associate Professor, Department of General Practice and Dental Public Health, The University of Texas School of Dentistry at Houston; Mr. Kookal is Clinical Informatics Research Data Warehouse Systems Analyst, Technology Services and Informatics, The University of Texas School of Dentistry at Houston; Ms. Fishbeck is a senior dental student, The University of Texas School of Dentistry at Houston; Mr. Thompson is a senior dental student, The University of Texas School of Dentistry at Houston; and Dr. Walji is Professor and Associate Dean, Department of Diagnostic and Biomedical Sciences, The University of Texas School of Dentistry at Houston. shawn.adibi@uth.tmc.edu. Dr. Adibi is Associate Professor, Department of General Practice and Dental Public Health, The University of Texas School of Dentistry at Houston; Mr. Kookal is Clinical Informatics Research Data Warehouse Systems Analyst, Technology Services and Informatics, The University of Texas School of Dentistry at Houston; Ms. Fishbeck is a senior dental student, The University of Texas School of Dentistry at Houston; Mr. Thompson is a senior dental student, The University of Texas School of Dentistry at Houston; and Dr. Walji is Professor and Associate Dean, Department of Diagnostic and Biomedical Sciences, The University of Texas School of Dentistry at Houston. AN - 27934670 AU - Adibi, S. S. AU - Kookal, K. K. AU - Fishbeck, N. M. AU - Thompson, C. R. AU - Walji, M. F. DA - Dec DP - NLM ET - 2016/12/10 IS - 12 KW - Adolescent Adult Aged Aged, 80 and over *Clinical Competence *Education, Dental Education, Dental, Graduate Facial Pain/*diagnosis Humans Middle Aged Pilot Projects Temporomandibular Joint Disorders/*diagnosis Young Adult *dental education *oral pain management *orofacial pain *temporomandibular disorders LA - eng N1 - 1930-7837 Adibi, Shawn S Kookal, Krishna Kumar Fishbeck, Nichole M Thompson, Chris R Walji, Muhammad F Journal Article United States J Dent Educ. 2016 Dec;80(12):1450-1456. PY - 2016 SN - 0022-0337 SP - 1450-1456 ST - Assessment of Diagnosed Temporomandibular Disorders and Orofacial Pain Conditions by Predoctoral Dental Students: A Pilot Study T2 - J Dent Educ TI - Assessment of Diagnosed Temporomandibular Disorders and Orofacial Pain Conditions by Predoctoral Dental Students: A Pilot Study VL - 80 ID - 4080 ER - TY - JOUR AB - Background Hypnosis is defined as "as an interaction in which the hypnotist uses suggested scenarios ("suggestions") to encourage a person's focus of attention to shift towards inner experiences". Aim of the work The focus of this review is to summarize the findings of controlled outcome studies investigating the potential of clinical hypnosis in pediatric populations. We will examine the following themes: anesthesia, acute and chronic pain, chemotherapy-related distress, along with other specific medical issues. Results Hypnosis is an effective method to reduce pain and anxiety before, during and after the administration of anesthetics, during local dental treatments, invasive medical procedures and in burn children. Hypnosis can be successfully used to manage recurrent headaches, abdominal pain, irritable bowel syndrome and chemotherapy-related distress. Hypnosis has an important role in managing symptoms and improving the quality of life of children suffering from asthma and cystic fibrosis and in facilitating the treatment of insomnia in school-age children. Finally, hypnosis can be effectively used for the treatment of some habitual disorders such as nocturnal enuresis and dermatologic conditions, including atopic dermatitis and chronic eczema Conclusions Clinical hypnosis seems to be a useful, cheap and side-effects free tool to manage fear, pain and several kinds of stressful experiences in pediatric populations. Children who receive self-hypnosis trainings achieve significantly greater improvements in their physical health, quality of life, and self-esteem. AD - Milton Erickson Institute, Torino, Italy.. info@ericksoninstitute.it. AN - 24165457 AU - Adinolfi, B. AU - Gava, N. DA - Sep 1 DP - NLM ET - 2013/10/30 IS - 2 KW - Anxiety Disorders Child Humans *Hypnosis Outcome Assessment, Health Care Pain *Quality of Life Treatment Outcome LA - eng N1 - Adinolfi, Barbara Gava, Nicoletta Journal Article Review Italy Acta Biomed. 2013 Sep 1;84(2):94-7. PY - 2013 SN - 0392-4203 (Print) 0392-4203 SP - 94-7 ST - Controlled outcome studies of child clinical hypnosis T2 - Acta Biomed TI - Controlled outcome studies of child clinical hypnosis VL - 84 ID - 3780 ER - TY - JOUR AB - BACKGROUND: Sickle cell disease (SCD) is of major public health concern globally, with majority of patients living in Africa. Despite its relevance, there is a dearth of research to determine the socio-demographic distribution and psychosocial impact of SCD in Ghana. The objective of this study was to examine the socio-demographic distribution and psychosocial consequences of SCD among patients in Ghana and to assess their quality of life and coping mechanisms. METHODS: A cross-sectional research design was used that involved the completion of questionnaires on socio-demographic characteristics, quality of life, coping mechanisms, anxiety and depression. Participants were 387 male and female patients attending a sickle cell clinic in a public hospital. RESULTS: Results showed that majority of the patients were single, female, less than 39 years old and had attained secondary school level of education or less. Also, patients were more satisfied by the presence of love, friends and relatives as well as home, community and neighbourhood environment. While pains of varied nature and severity were the major reasons for attending hospital in SCD condition, going to the hospital as well as having faith in God was the most frequently reported mechanisms for coping with an unbearable SCD attacks. Results of multiple regression analysis showed that some socio-demographic and quality of life indicators had strong associations with anxiety and/or depression. CONCLUSIONS: It is recommended that a holistic intervention strategy incorporating psychosocial dimensions should be considered in the treatment and management of SCD. AD - Department of Psychology, Regent University College, Accra, Ghana. Vincent.adzika@regentghana.net. Department of Psychology, Regent University College, Accra, Ghana. Department of Epidemiology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana. AN - 28143586 AU - Adzika, V. A. AU - Glozah, F. N. AU - Ayim-Aboagye, D. AU - Ahorlu, C. S. C2 - PMC5282775 DA - Jan 31 DO - 10.1186/s41043-017-0081-5 DP - NLM ET - 2017/02/02 IS - 1 KW - *Adaptation, Psychological Adolescent Adult Anemia, Sickle Cell/*psychology Anxiety/*etiology Cross-Sectional Studies Demography Depression/*etiology Ghana Hospitals, Public Humans Middle Aged *Quality of Life Residence Characteristics *Social Environment Spirituality Surveys and Questionnaires Young Adult *Anxiety *Depression *Ghana *Sickle cell disease *Socio-demographic characteristics LA - eng N1 - 2072-1315 Adzika, Vincent A Glozah, Franklin N Ayim-Aboagye, Desmond Ahorlu, Collins S K Journal Article J Health Popul Nutr. 2017 Jan 31;36(1):4. doi: 10.1186/s41043-017-0081-5. PY - 2017 SN - 1606-0997 (Print) 1606-0997 SP - 4 ST - Socio-demographic characteristics and psychosocial consequences of sickle cell disease: the case of patients in a public hospital in Ghana T2 - J Health Popul Nutr TI - Socio-demographic characteristics and psychosocial consequences of sickle cell disease: the case of patients in a public hospital in Ghana VL - 36 ID - 4030 ER - TY - JOUR AB - BACKGROUND: This study aimed to verify and compare central auditory processing (CAP) performance in migraine with and without aura patients and healthy controls. METHODS: Forty-one volunteers of both genders, aged between 18 and 40 years, diagnosed with migraine with and without aura by the criteria of "The International Classification of Headache Disorders" (ICDH-3 beta) and a control group of the same age range and with no headache history, were included. Gaps-in-noise (GIN), Duration Pattern test (DPT) and Dichotic Digits Test (DDT) tests were used to assess central auditory processing performance. RESULTS: The volunteers were divided into 3 groups: Migraine with aura (11), migraine without aura (15), and control group (15), matched by age and schooling. Subjects with aura and without aura performed significantly worse in GIN test for right ear (p = .006), for left ear (p = .005) and for DPT test (p < .001) when compared with controls without headache, however no significant differences were found in the DDT test for the right ear (p = .362) and for the left ear (p = .190). CONCLUSIONS: Subjects with migraine performed worsened in auditory gap detection, in the discrimination of short and long duration. They also presented impairment in the physiological mechanism of temporal processing, especially in temporal resolution and temporal ordering when compared with controls. Migraine could be related to an impaired central auditory processing. CLINICAL TRIAL REGISTRATION: Research Ethics Committee (CEP 0480.10) - UNIFESP. AD - Division of Investigation and Treatment of Headaches (DITH), Neurology and Neurosurgery Department, Federal University of São Paulo, UNIFESP, São Paulo, SP, Brazil. agessi.larissa@gmail.com. AN - 25380661 AU - Agessi, L. M. AU - Villa, T. R. AU - Dias, K. Z. AU - Carvalho Dde, S. AU - Pereira, L. D. C2 - PMC4232973 DA - Nov 8 DO - 10.1186/1129-2377-15-72 DP - NLM ET - 2014/11/09 IS - 1 KW - Acoustic Stimulation Adolescent Adult Auditory Perception/*physiology Case-Control Studies Dichotic Listening Tests Female Humans Male Migraine with Aura/*physiopathology Migraine without Aura/*physiopathology Young Adult LA - eng N1 - 1129-2377 Agessi, Larissa Mendonça Villa, Thaís Rodrigues Dias, Karin Ziliotto Carvalho, Deusvenir de Souza Pereira, Liliane Desgualdo Journal Article J Headache Pain. 2014 Nov 8;15(1):72. doi: 10.1186/1129-2377-15-72. PY - 2014 SN - 1129-2369 (Print) 1129-2369 SP - 72 ST - Central auditory processing and migraine: a controlled study T2 - J Headache Pain TI - Central auditory processing and migraine: a controlled study VL - 15 ID - 3680 ER - TY - JOUR AB - Children with chronic pain frequently experience impairment in the school setting, but we do not yet understand how unique these struggles are to children with primary pain conditions compared to peers with disease-related pain or those without chronic pain symptoms. The objective of this study is to examine school functioning, defined as school attendance rates, overall quality of life in the school setting, and school nurse visits among adolescents with primary pain conditions, those with juvenile idiopathic arthritis (JIA)-related pain, and healthy peers. Two hundred and sixty adolescents participated in the study, including 129 with primary pain conditions, 61 with JIA, and 70 healthy comparison adolescents. They completed self- and parent-reported measures of school function. Findings show that as a group, youth with primary pain conditions reported more school absences, lower quality of life in the school setting, and more frequent school nurse visits compared to both adolescents with JIA-related pain and healthy peers. We conclude that compared to those who experience pain specific to a disease process, adolescents with primary pain conditions may face unique challenges in the school setting and may require more support to help them succeed in school in spite of pain. AU - Agoston, Anna Monica AU - Gray, Laura S. AU - Logan, Deirdre E. DA - 2016/11/30/ DO - 10.3390/children3040039 DP - PubMed IS - 4 J2 - Children (Basel) KW - child and adolescent chronic pain school functioning LA - eng PY - 2016 SN - 2227-9067 ST - Pain in School T2 - Children (Basel, Switzerland) TI - Pain in School: Patterns of Pain-Related School Impairment among Adolescents with Primary Pain Conditions, Juvenile Idiopathic Arthritis Pain, and Pain-Free Peers UR - http://www.ncbi.nlm.nih.gov/pubmed/27916882 VL - 3 ID - 63 ER - TY - JOUR AB - Recurrent headache is common in children. Among them migraine is the most common disabling cause of primary headache. It causes serious disability in child's life and family. It causes negative impact on their quality of life. Clinical characteristic of migraine in children differ from adult. It may be shorter in duration and bifrontal or bitemporal in location in contrast to adult which is longer in duration and usually unilateral. It is less common before 3 years of age. Males are more affected before puberty. But after puberty females are predominantly affected. Intensity of pain is moderate to severe. There are some triggering factors. Positive family history usually present. Disability can be assessed by PedMIDAS scale in children and adolescents which is modified version of MIDAS scale for adult. Diagnosis of migraine usually clinical but evaluation should be done to exclude severe underlying secondary cause. Management consists of pharmacological and non pharmacological approach. Parental education, life style modification is the mainstay of management. Acute treatment consists of Acetaminophen, NSAIDs and Triptans. Among Triptans, Sumatriptan nasal spray is only found effective for children. Preventive therapy aims to decrease frequency and severity of headache. Flunarizine, Propranolol, Amitryptylline, Levetiracetam, Valproate, Topiramate are found effective in pediatric age group. Pediatrician should evaluate the child to exclude secondary cause of headache when indicated. They should have also proper knowledge and skills to manage a child having migraine to improve their quality of life and academic achievement. AD - Dr Sanjida Ahmed, Medical Officer, Institute of Pediatric Neuro-disorder and Autism (IPNA), Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbagh, Dhaka, Bangladesh. AN - 27612914 AU - Ahmed, S. AU - Tabassum, S. AU - Rahman, S. M. AU - Akhter, S. AU - Rahman, M. M. AU - Bayes, F. AU - Roy, S. DA - Jul DP - NLM ET - 2016/09/11 IS - 3 KW - Adolescent Adult Anti-Inflammatory Agents, Non-Steroidal/therapeutic use Child Child, Preschool Female *Headache/complications/diagnosis/drug therapy Humans Male *Migraine Disorders/complications/diagnosis/drug therapy Quality of Life Topiramate/therapeutic use LA - eng N1 - Ahmed, S Tabassum, S Rahman, S M Akhter, S Rahman, M M Bayes, F Roy, S Journal Article Review Bangladesh Mymensingh Med J. 2016 Jul;25(3):589-96. PY - 2016 SN - 1022-4742 (Print) 1022-4742 SP - 589-96 ST - Migraine in Children: A Review T2 - Mymensingh Med J TI - Migraine in Children: A Review VL - 25 ID - 2968 ER - TY - JOUR AB - Background: Neck and low back pain are significant health problems due to their high prevalence among the general population. Educational intervention commonly aims to reduce the symptoms and risk for additional problems by increasing the participant's knowledge, which in turn will alter the person's behavior. The primary aim of this study was to review randomize controlled trials (RCTs) to gain insights into the effectiveness of education for the prevention and treatment of non-specific neck and low back pain. Methods: Publications were systematically searched from 1982 to March 2015 in several databases. Relevant RCTs were retrieved and assessed for methodological quality. Meta-analysis was conducted to examine the effectiveness of education for the prevention and treatment of non-specific neck and low back pain. The overall quality of evidence was assessed using the GRADE system. Results: Thirty-six RCTs (30 high-quality studies) were identified. A total of 15 RCTs, which compared education programs to no education program, were included for further analysis. All studies included investigated the effectiveness of education with intermediate-and long-term follow-ups. The results showed that education programs were not effective in preventing and treating neck pain as well as treating low back pain. Conflicting evidence was found for the effectiveness of education on prevention of low back pain. Conclusions: Evidence suggests that education programs are not recommended in preventing or treating neck pain as well as treating low back pain, unless supplementary high-quality studies provide evidence to the contrary. (C) 2015 Elsevier Ltd. All rights reserved. AN - WOS:000373615700008 AU - Ainpradub, K. AU - Sitthipornvorakul, E. AU - Janwantanakul, P. AU - van der Beek, A. J. DA - Apr DO - 10.1016/j.math.2015.10.012 N1 - Ainpradub, Kantheera Sitthipornvorakul, Ekalak Janwantanakul, Prawit van der Beek, Allard J. Janwantanakul, Prawit/0000-0001-7799-2552 1532-2769 PY - 2016 SN - 1356-689X SP - 31-41 ST - Effect of education on non-specific neck and low back pain: A meta-analysis of randomized controlled trials T2 - Manual Therapy TI - Effect of education on non-specific neck and low back pain: A meta-analysis of randomized controlled trials UR - ://WOS:000373615700008 VL - 22 ID - 2173 ER - TY - JOUR AB - BACKGROUND: The association between the weight of school bag and Low Back Pain (LBP) amongst students remains under intense debate worldwide. This study aimed to estimate the prevalence of LBP amongst public high school students (14 to 19 years) in Kuwait and to investigate the association between LBP and the weight of school bags. METHODS: An analytical cross-sectional study using multistage cluster random sampling with probability proportional to size was conducted on a total of 950 public high school students from all governorates. Data on LBP were collected through face-to-face interviews using a structured questionnaire. A 0-10 Numeric Pain Rating Scale was used to rate the intensity of LBP. The students' height and weight in addition to the weight of their school bags were measured using appropriate weight and height scales. Logistic regression was used to investigate the association between the weight of school bags and LBP while adjusting for potential confounders. RESULTS: The estimated lifetime, 6-month, and 1-month prevalence of LBP were 70.3% (95% CI: 67.30-73.21%), 49.1% (95% CI: 45.83-52.28%), and 30.8% (95% CI: 27.81-33.78%) respectively, with significantly higher prevalence amongst females compared to males (p < 0.001). The absolute weight of school bag was not significantly associated with LBP neither in univariable nor multivariable analysis. The relative weight of school bag (as a percentage of the body weight) was significantly associated with LBP in univariable analysis but not in multivariable analysis. The perceived heaviness of school bag, however, was found to be significantly associated with LBP throughout the analysis (p < 0.001). CONCLUSION: In conclusion, LBP amongst high school students in Kuwait seems to be very common with a prevalence resembling that of high-income countries. Our data suggest that the perceived heaviness of school bag is far more important than the actual bag weight. Current recommendations about the weight of school bags, which are not supported by evidence, should be revised to take into account the students' perceived heaviness of school bag. AU - Akbar, Fatemah AU - AlBesharah, Muneera AU - Al-Baghli, Jumana AU - Bulbul, Farah AU - Mohammad, Dana AU - Qadoura, Bann AU - Al-Taiar, Abdullah DA - 2019/01/22/ DO - 10.1186/s12891-019-2398-2 DP - PubMed IS - 1 J2 - BMC Musculoskelet Disord KW - Adolescent Adolescents Cross-Sectional Studies Female Humans Kuwait Low Back pain Male Prevalence Random Allocation School bags Schools Students Weight-Bearing Young Adult LA - eng PY - 2019 SN - 1471-2474 SP - 37 ST - Prevalence of low Back pain among adolescents in relation to the weight of school bags T2 - BMC musculoskeletal disorders TI - Prevalence of low Back pain among adolescents in relation to the weight of school bags UR - http://www.ncbi.nlm.nih.gov/pubmed/30670005 VL - 20 ID - 60 ER - TY - JOUR AB - Reducing the impact of rheumatic diseases in childhood is the fundamental objective of every member of the multi-disciplinary team involved in the care of affected children and families. The means by which this objective may be achieved are broad and include the implementation of a range of non-pharmacological therapies to address the effects of rheumatic diseases on the physical development of the child. In addition, the treating team must be aware of the psychosocial impact that these diseases may have and the ways in which this may be minimized. This chapter is devoted to an examination of some of the non-pharmacological issues that arise in the management of the commonest rheumatic disease found in children, juvenile idiopathic arthritis (JIA). Aspects of physical rehabilitation, schooling, medication compliance, pain management and family dynamics are discussed, as are interventions to reduce the impact of this disease and its sequelae, utilizing, where possible, evidence-based principles from the literature. Although specific issues applicable to children with arthritis will be discussed, the broad principles of much of what follows applies to all of the rheumatic diseases in childhood. AN - WOS:000178831100002 AU - Akikusa, J. D. AU - Allen, R. C. DA - Jul DO - 10.1053/berh.2002.0232 IS - 3 N1 - Akikusa, JD Allen, RC 1521-1770 PY - 2002 SN - 1521-6942 SP - 333-345 ST - Reducing the impact of rheumatic diseases in childhood T2 - Best Practice & Research in Clinical Rheumatology TI - Reducing the impact of rheumatic diseases in childhood UR - ://WOS:000178831100002 VL - 16 ID - 2827 ER - TY - JOUR AB - We evaluated 1400 randomly selected Saudi children in grades 1 through 9 to determine the prevalence of migraine and tension-type headache. Of the 1400 distributed questionnaires, 1181 (84.3%) were completed properly and so served as the basis for analysis. There were 573 boys (48.5%) and 608 girls (51.5%). Ages ranged from 6 to 18 years. Five hundred eighty-eight children (49.8%; 272 boys and 316 girls) had recurrent headache episodes not related to febrile illness in the year preceding the survey. Eighty-four children (7.1%; 37 boys and 47 girls) had recurrent episodes of migraine, and 504 (42.7%; 232 boys and 272 girls) had recurrent episodes of nonmigraine headache. For both boys and girls, the age-specific prevalence rate for nonmigraine headache rose steadily from around 15% at aged 6 to 7 years to nearly 60% after aged 15. For migraine, there was a sharp increase in the prevalence rate (from around 2% to around 9%) at aged 10 to 11, also in both boys and girls. Age-adjusted prevalence for migraine between aged 6 and 15 was 6.2%. Due to the relatively poor sensitivity of some of the IHS criteria in children, this figure may underestimate the true magnitude of migraine in the population studied. AN - WOS:000175558800007 AU - Al Jumah, M. AU - Awada, A. AU - Al Azzam, S. DA - Apr DO - 10.1046/j.1526-4610.2002.02081.x IS - 4 N1 - Al Jumah, M Awada, A Al Azzam, S 1526-4610 PY - 2002 SN - 0017-8748 SP - 281-286 ST - Headache syndromes amongst schoolchildren in Riyadh, Saudi Arabia T2 - Headache TI - Headache syndromes amongst schoolchildren in Riyadh, Saudi Arabia UR - ://WOS:000175558800007 VL - 42 ID - 2832 ER - TY - JOUR AB - Background/Objective: Primary headaches are common in the pediatric and adolescent population and can be disabling for them and their families. We aimed to assess the prevalence and burden of primary headache disorders among children and adolescents in Kuwait. Methods: A cross-sectional community-based study included Kuwaiti population aged 6-17 years. They were randomly recruited from all six governorates of Kuwait using stratified multistage cluster sampling. The Headache-Attributed Restriction, Disability, and Social Handicap and Impaired Participation (HARDSHIP) questionnaire for children and adolescents was used to collect the data. Results: Data were collected from 3,423 subjects; 664 subjects were diagnosed as having primary headache disorders. The mean age was 12.61 +/- 2.51 years and 64.2% were females. One year prevalence of headache was 19.4%. It was significantly prevalent in females compared to males (25.2% vs. 13.8%; P < 0.001). Primary headache disorder significantly increased in age group 12-17 when compared to age group 6-11 years (25.8% vs. 10.4 %; p < 0.001). One year primary headache prevalence showed non-significant differences in both males and females in age group 6-11 years (10.1% in males vs. 10.6% in females; P < 0.79), while it was significantly higher in female vs. males (38.1% vs. 15.8%; P < 0.001) in age group 12-17 years. Migraine prevalence was 10.9% followed by tension type headache (TTH) 6.2% and chronic headache 0.9%. Medical care utilization was reported in 67% of our cohort. The majority (95%) of the patients received symptomatic drugs for headache attacks and only 7.5% used preventive medication. The students with headache lost a mean of 1.29 +/- 1.23 days of school, reported mean of 1.16 +/- 1.50 days they could not do activities they had wanted to. Their parents lost a mean of 1.01 +/- 1.02 days of work because of headaches of their children during the preceding 4 weeks of the study. Conclusions: The estimated 1 year prevalence of headache was 19.4% overall. Primary headache prevalence increased with age and it was more prevalent in female adolescents compared to males of the same age. Headache disorders in children/adolescents affect school and social activities as well as their parents work. The awareness for early diagnosis and preventive medications for headache in this age group may reduce the headache burden. AN - WOS:000477814500001 AU - Al-Hashel, J. Y. AU - Ahmed, S. F. AU - Alroughani, R. C7 - 793 DA - Jul DO - 10.3389/fneur.2019.00793 N1 - Al-Hashel, Jasem Yousef Ahmed, Samar Farouk Alroughani, Raed PY - 2019 SN - 1664-2295 ST - Prevalence and Burden of Primary Headache Disorders in Kuwaiti Children and Adolescents: A Community Based Study T2 - Frontiers in Neurology TI - Prevalence and Burden of Primary Headache Disorders in Kuwaiti Children and Adolescents: A Community Based Study UR - ://WOS:000477814500001 VL - 10 ID - 1897 ER - TY - JOUR AB - BACKGROUND: The recommended weight of schoolbags is less than 10-15% of the body weight. Heavy schoolbags may result in musculoskeletal and psychological problems among primary school children. This study was conducted to assess the weight of school bags in relation to primary school children weight, and to look for the prevalence of back pain among them in Al-Ahsa, Saudi Arabia. METHODS: A total of 2567 school children were included in this study both from rural and urban areas of Al-Ahsa, Saudi Arabia. A cross sectional survey was conducted in which a pre-tested questionnaire was used to ask about demographic profile, and symptoms of back pain. The weight of the school bags and the school children was measured. RESULTS: 1860 school children (72.46%) out of 2567 were carrying bags of weight more than 15% of their body weight. The prevalence of heavy school bags was higher among the female children as compared with the male children. Back pain was reported by 42% of the school children. CONCLUSIONS: The weight of schoolbags of Al-Ahsa primary school children were higher than the internationally acceptable standards and as a result back pain was reported by 42% of school children. The school authorities and ministry of health should further evaluate and take the necessary steps to rectify the situation. AU - Al-Saleem, Saleem Ali AU - Ali, Ayub AU - Ali, Sayed Ibrahim AU - Alshamrani, Abdulaziz Anazi AU - Almulhem, Ammar Mohammed AU - Al-Hashem, Muataz Hasan DA - 2016/02// DO - 10.4172/2161-1165.1000222 DP - PubMed IS - 1 J2 - Epidemiology (Sunnyvale) KW - Back pain School bags School children LA - eng PY - 2016 SN - 2161-1165 ST - A Study of School Bag Weight and Back Pain among Primary School Children in Al-Ahsa, Saudi Arabia T2 - Epidemiology (Sunnyvale, Calif.) TI - A Study of School Bag Weight and Back Pain among Primary School Children in Al-Ahsa, Saudi Arabia UR - http://www.ncbi.nlm.nih.gov/pubmed/27570708 VL - 6 ID - 76 ER - TY - JOUR AB - Objectives: To determine the prevalence of headache and migraine, to identify symptoms that accompany headache attack, and to determine the possible effect of headache on school attendance, among high school students. Methods: A cross-sectional, questionnaire-based study of secondary school students of the National Guard Housing in Riyadh, Kingdom of Saudi Arabia, was executed during the academic year of 2002 and 2003. A sample of 1750 students was included from 4 schools by systemic random sampling for each school. The questionnaire included demographic data. The second part includes specific questions on headache, and whether there had been headache in the year preceding the survey, type of headache, and its diagnosis according to International Headache Society (IHS) criteria. Possible effect of headache on school attendance was recorded. Results: Approximately one-third of the entire study sample had recurrent headache episodes not related to febrile illness in the year preceding the survey. Female students showed a significantly higher prevalence than males of migraine, as well as non-migraine headache, with the least prevalence among the younger students of ages 16-17 years. More than one-third of all students were absent from school due to headache. Conclusion: Recurrent headache is prevalent among the high school students, and more among female students. These prevalence rates are comparable with those reported elsewhere. Health education sessions at schools, primary care clinics, and the society in general are recommended to increase awareness for this common adolescent's neurological problem. AN - WOS:000263497800020 AU - Al-Tulaihi, B. A. AU - Al-Jumah, M. A. DA - Jan IS - 1 N1 - Al-Tulaihi, Bader A. Al-Jumah, Mohammed A. PY - 2009 SN - 0379-5284 SP - 120-124 ST - Prevalence of migraine and non-migraine headache among high school students at the National Guard Housing in Riyadh, Saudi Arabia T2 - Saudi Medical Journal TI - Prevalence of migraine and non-migraine headache among high school students at the National Guard Housing in Riyadh, Saudi Arabia UR - ://WOS:000263497800020 VL - 30 ID - 2627 ER - TY - JOUR AB - Background:The prevalence of primary headaches in the pediatric population is shaped by many factors, of which pubertal status may possibly play a substantial role. Epidemiological studies in the pediatric population in the gulf region remain scarce. Aims and objectives:To examine the impact of puberty on the prevalence of primary headache disorders among female schoolchildren in Kuwait. Methods:We conducted a cross-sectional study that included Kuwaiti primary and middle schoolgirls in randomly selected schools located in two governorates in Kuwait during the academic year 2018/2019. Prevalence of headache was assessed using the Headache-Attributed Restriction, Disability, Social Handicap and Impaired Participation (HARDSHIP) questionnaire for children and adolescents. Female students were asked about their menarchal status and whether they attained menarche before or after experiencing headaches. Results:The questionnaire was completed by 669 girls with a mean age of 11.44 +/- 2.14 years. The 1-year prevalence of migraine headache disorder among girls was 23.62%, and the lifetime prevalence of any headache was 84.9%, whereas the 1-year prevalence of primary headache disorders was 47.98%. The mean age of girls with headaches was 11.44 +/- 2.14 years. With respect to diagnostic criteria, migraine headache was the most frequently reported (23.62%), followed by tension-type headaches (20.93%), chronic headaches (2.99%), and probable medication-overuse headaches (0.45%). Postpubertal females were at significantly higher risk of having primary headaches compared to their prepubertal counterparts (64.26 vs. 34%;p< 0.0001). All types of primary headaches were more significantly prevalent among postpubertal girls compared to those who are prepubertal. Conclusion:Migraine headache is commonly reported among Kuwaiti schoolgirls. Postpubertal females are at higher risk of developing primary headaches compared to prepubertal females. Pubertal transition and female sex hormones may play a significant role in the pathophysiology of headaches, migraines in particular, and further research is therefore needed to investigate the underlying mechanisms. AN - WOS:000556931200001 AU - Alashqar, A. AU - Shuaibi, S. AU - Ahmed, S. F. AU - AlThufairi, H. AU - Owayed, S. AU - AlHamdan, F. AU - Alroughani, R. AU - Al-Hashel, J. Y. C7 - 594 DA - Jul DO - 10.3389/fneur.2020.00594 N1 - Alashqar, Abdelrahman Shuaibi, Sameera Ahmed, Samar Farouk AlThufairi, Hawraa Owayed, Shaikhah AlHamdan, Fajer Alroughani, Raed Al-Hashel, Jasem Yousef AlAshqar, Abdelrahman/ABB-2545-2020 AlAshqar, Abdelrahman/0000-0002-1283-7460 PY - 2020 SN - 1664-2295 ST - Impact of Puberty in Girls on Prevalence of Primary Headache Disorder Among Female Schoolchildren in Kuwait T2 - Frontiers in Neurology TI - Impact of Puberty in Girls on Prevalence of Primary Headache Disorder Among Female Schoolchildren in Kuwait UR - ://WOS:000556931200001 VL - 11 ID - 1808 ER - TY - JOUR AB - Purpose: To develop a conceptual model representing the impact of musculoskeletal impairments (MSIs) in the lives of children in Malawi. Method: A total of 169 children with MSIs (CMSIs), family and other community members participated in 57 interviews, focus groups and observations. An inductive approach to data analysis was used to conceptualise the impact of MSIs in children's day-to-day lives. Results: The main themes that emerged were Indignity, Exclusion, Pain and Hunger. Indignity represents various affronts to children's sense of inherent equal worth as human beings, for example when bullied by peers. Exclusion refers to CMSIs being excluded from three core daily activities: school, play and household chores. Some CMSIs experienced Pain, for example as an outcome of striving to participate. Children with severe mobility impairments were at increased risk of Hunger, having less access to food outside the home and placing a burden of care on the family that could restrict household productivity. Household Poverty was therefore included in the model, as this household impact was inseparable from the impact on CMSIs. Conclusion: It is recommended that rehabilitation interventions are planned and evaluated with consideration to their impact on Exclusion, Indignity, Pain, Hunger and Household Poverty using multi-faceted partnerships. AN - WOS:000307226400008 AU - Alavi, Y. AU - Jumbe, V. AU - Hartley, S. AU - Smith, S. AU - Lamping, D. AU - Muhit, M. AU - Masiye, F. AU - Lavy, C. DO - 10.3109/09638288.2012.662260 IS - 20 N1 - Alavi, Yasmene Jumbe, Vincent Hartley, Sally Smith, Sarah Lamping, Donna Muhit, Mohammad Masiye, Francis Lavy, Chris Jumbe, Vincent C./AAF-3280-2020; Masiye, Francis/ABI-2943-2020 PY - 2012 SN - 0963-8288 SP - 1736-1746 ST - Indignity, exclusion, pain and hunger: the impact of musculoskeletal impairments in the lives of children in Malawi T2 - Disability and Rehabilitation TI - Indignity, exclusion, pain and hunger: the impact of musculoskeletal impairments in the lives of children in Malawi UR - ://WOS:000307226400008 VL - 34 ID - 2458 ER - TY - JOUR AB - BACKGROUND: Tension-type headache and migraine are among the most prevalent chronic disorders in children/adolescents. Data on health care utilization for headache in this age group, however, are sparse. METHODS: In 1399 grammar school students (aged 12-19 years) with headache in the last six months in Germany a) the burden of disease for headache (mean intensity, mean frequency in the last three months and PedMIDAS means), b) medical care utilization defined by proportion of students consulting a physician in the last 12 months and/or taking analgetic drugs in the last three months by headache types (migraine and tension-type headache) and by burden of disease were assessed. RESULTS: Primary headache substantially impaired daily living activities in adolescents which was mainly related to migraine. Medical care utilization and drug use, however, was low (consulting a physician: 12.0 %, 95 %-CI = [10.3-13.8]; taking analgetic drugs: 29.9 %, 95 %-CI = [27.5-32.4]) - even among students with severe headache (physician consultation: <35 %; taking analgetic drugs: <63 %). Two thirds of students with any headache and 40 % of those with migraine had neither seen a physician nor used analgetic drugs because of their headache in the preceding 12 months. CONCLUSIONS: Adolescents with headache might too rarely seek professional help for treatment of headache. Health promotion in adolescents should increase awareness for evidence-based treatment options for headache. AU - Albers, Lucia AU - Straube, Andreas AU - Landgraf, Mirjam N. AU - Filippopulos, Filipp AU - Heinen, Florian AU - von Kries, Rüdiger DA - 2015 DO - 10.1186/s10194-015-0534-4 DP - PubMed J2 - J Headache Pain KW - Adolescent Adult Child Cost of Illness Female Germany Headache Humans Male Migraine Disorders Patient Acceptance of Health Care Schools Students Tension-Type Headache Young Adult LA - eng PY - 2015 SN - 1129-2377 SP - 534 ST - Migraine and tension type headache in adolescents at grammar school in Germany - burden of disease and health care utilization T2 - The Journal of Headache and Pain TI - Migraine and tension type headache in adolescents at grammar school in Germany - burden of disease and health care utilization UR - http://www.ncbi.nlm.nih.gov/pubmed/26055241 VL - 16 ID - 54 ER - TY - JOUR AB - OBJECTIVES: Pain is prevalent among youth with sickle cell disease (SCD). However, previous research has been limited by small sample sizes and lacked examinations of developmental differences in pain, which are critical to minimizing the development of chronic pain as youth transition into adulthood. The primary aim of the current study was to compare pain and pain interference across 4 developmental groups in a large sample of youth with SCD. The secondary aim was to identify risk factors for greater pain and pain interference. MATERIALS AND METHODS: Utilizing a cross-sectional study design, the expression and predictors of pain and pain interference were compared across 4 developmental stages: toddlers/preschoolers (2 to 4 y), school-aged children (5 to 7 y), preadolescents (8 to 12 y), and adolescents (13 to 18 y). Participants included 386 youth with SCD and their caregivers. RESULTS: Caregiver-reported pain and pain interference and youth-reported pain interference increased across developmental groups and plateaued approaching adolescence (multivariate analyses of variance P=0.002 for pain and P<0.001 for pain interference). Elevated fatigue, anxiety, and perceived difficulties with pain management were the most robust predictors of higher youth- and caregiver-reported pain (βs ranging from 0.15 to 0.68; P<0.001) and pain interference (βs ranging from 0.18 to 0.64; P<0.001). DISCUSSION: Disease and treatment-related variables were not associated with pain. Self-reported pain was elevated in older versus younger developmental groups and was largely linked to anxiety, fatigue, and perceptions of pain management, thus highlighting the modifiable nature of factors influencing pain among youth with SCD. AD - Departments of Psychology. Department of Psychology, Concordia University, Montréal, QC, Canada. Biostatistics. Departments of Pediatric Psychology and Pediatric Pain and Palliative Medicine, Helen DeVos Children's Hospital, Grand Rapids. Department of Pediatrics and Human Development, Michigan State University College of Human Medicine, East Lansing, MI. Hematology, St. Jude Children's Research Hospital, Memphis, TN. Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta. Department of Pediatrics, Emory University School of Medicine, Atlanta, GA. AN - 33093339 AU - Alberts, N. M. AU - Kang, G. AU - Li, C. AU - Richardson, P. A. AU - Hodges, J. AU - Hankins, J. S. AU - Klosky, J. L. DA - Jan DO - 10.1097/ajp.0000000000000889 DP - NLM ET - 2020/10/24 IS - 1 LA - eng N1 - 1536-5409 Alberts, Nicole M Kang, Guolian Li, Chen Richardson, Patricia A Hodges, Jason Hankins, Jane S Klosky, James L Journal Article Research Support, Non-U.S. Gov't United States Clin J Pain. 2021 Jan;37(1):43-50. doi: 10.1097/AJP.0000000000000889. PY - 2021 SN - 0749-8047 SP - 43-50 ST - Pain in Youth With Sickle Cell Disease: A Report From the Sickle Cell Clinical Research and Intervention Program T2 - Clin J Pain TI - Pain in Youth With Sickle Cell Disease: A Report From the Sickle Cell Clinical Research and Intervention Program VL - 37 ID - 4028 ER - TY - JOUR AB - BACKGROUND: Diet therapies may be recommended for pediatric functional gastrointestinal disorders (FGIDs). However, little is known about the frequency with which diet therapy is recommended in FGIDs. Our aims were to determine and contrast the frequency and types of diet recommendations provided to children with FGIDs by pediatric gastroenterologists (PGIs) versus primary care pediatricians (PCPs). METHODS: A retrospective chart review was performed using data from a large, metropolitan children's academic healthcare system to identify subjects meeting Rome IV criteria for functional abdominal pain, functional dyspepsia, irritable-bowel syndrome (IBS), and/or abdominal migraine over a period of 23 months. RESULTS: Of 1929 patient charts reviewed, 268 were included for further analyses. Of these, 186 patients (69%) were seen by a PGI and 82 (31%) by a PCP. The most common diagnosis was IBS (49% for PGIs and 71% for PCPs). Diet recommendations were provided to 115 (43%) patients (PGI group: 86 [75%] vs PCP group: 29 [25%]; P < .1). The most frequent recommendations were high fiber (PGI: 15%; PCP: 14%) and low fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs) diet (PGI: 12%; PCP: 4%). Of those provided with diet recommendations, only 20% (n = 23) received an educational consult by a dietitian. Provision of diet recommendations was not affected by years in practice. CONCLUSION: Despite increasing awareness of the role of diet in the treatment of childhood FGIDs, a minority of patients receive diet recommendations in tertiary care or primary care settings. When diet recommendations were given, there was great variability in the guidance provided. AD - Section of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, East Tennessee State University, Johnson City, Tennessee, USA. Dan L, Duncan Institute for Clinical and Translational Research, Baylor College of Medicine, Houston, Texas, USA. Section of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA. USDA/ARS Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA. AN - 32017170 AU - Alfaro Cruz, L. AU - Minard, C. AU - Guffey, D. AU - Chumpitazi, B. P. AU - Shulman, R. J. C2 - PMC7398825 C6 - NIHMS1063805 DA - Nov DO - 10.1002/jpen.1771 DP - NLM ET - 2020/02/06 IS - 8 KW - Child Diet Fermentation *Gastrointestinal Diseases Humans *Irritable Bowel Syndrome Monosaccharides Oligosaccharides Retrospective Studies *FODMAPs *ibs *diet *education article to disclose. LA - eng N1 - 1941-2444 Alfaro Cruz, Ligia Orcid: 0000-0001-6583-5920 Minard, Charles Guffey, Danielle Chumpitazi, Bruno P Shulman, Robert J K23 DK101688/DK/NIDDK NIH HHS/United States R01 NR013497/NR/NINR NIH HHS/United States R03 DK117219/DK/NIDDK NIH HHS/United States P30 DK056338/DK/NIDDK NIH HHS/United States 6250-51000-043/the Daffy's Foundation, and the USDA/ARS/ P30 DK56338/the Daffy's Foundation, and the USDA/ARS/ U01 DK112194/DK/NIDDK NIH HHS/United States Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't JPEN J Parenter Enteral Nutr. 2020 Nov;44(8):1525-1529. doi: 10.1002/jpen.1771. Epub 2020 Feb 4. PY - 2020 SN - 0148-6071 (Print) 0148-6071 SP - 1525-1529 ST - Does a Minority of Children With Functional Gastrointestinal Disorders Receive Formal Diet Advice? T2 - JPEN J Parenter Enteral Nutr TI - Does a Minority of Children With Functional Gastrointestinal Disorders Receive Formal Diet Advice? VL - 44 ID - 3934 ER - TY - JOUR AB - The origin of recurrent abdominal pain of ''non-organic origin'' is believed to be psychogenic in most cases. But the pathogenesis of the pain itself is unknown. To test the hypothesis that recurrent abdominal pain of non-organic origin is related to increased pain sensitivity in the myofascial elements of the abdominal wall itself, an investigation of pain pressure threshold of the abdominal wall, close to the umbilicus, was carried out. Altogether 140 children in the fourth school grade, approximately 11 years old, were tested for pressure pain threshold. Two groups were constituted: one without pain symptoms (no recurrent abdominal pain, chest pains or headache (n = 50)) and one with recurrent abdominal pain (n = 49). The pressure pain threshold differed significantly (p < 0.0001). To support the hypothesis that recurrent abdominal pain is a part phenomenon of a specific pattern of muscular tension and tenderness, the pressure pain threshold was tested in five other muscles, with significant results. AN - WOS:A1993LD67000012 AU - Alfven, G. DA - May DO - 10.1111/j.1651-2227.1993.tb12727.x IS - 5 N1 - Alfven, g PY - 1993 SN - 0803-5253 SP - 481-483 ST - THE PRESSURE PAIN THRESHOLD (PPT) OF CERTAIN MUSCLES IN CHILDREN SUFFERING FROM RECURRENT ABDOMINAL-PAIN OF NONORGANIC ORIGIN - AN ALGOMETRIC STUDY T2 - Acta Paediatrica TI - THE PRESSURE PAIN THRESHOLD (PPT) OF CERTAIN MUSCLES IN CHILDREN SUFFERING FROM RECURRENT ABDOMINAL-PAIN OF NONORGANIC ORIGIN - AN ALGOMETRIC STUDY UR - ://WOS:A1993LD67000012 VL - 82 ID - 2955 ER - TY - JOUR AB - Psychosomatic symptoms among children are believed to be commonplace. In this investigation by questionnaire, 47% of 1333 schoolchildren reported one or several symptoms, such as recurrent abdominal pain, headache, chest pains, loss of appetite and disturbances in bowel function. Coexistence of such symptoms was considerable and if a child had one of these, the probability that it would have one or more other symptoms was significantly increased. This correlation may strengthen both the suspicion that these symptoms are often psychosomatic and the idea that they have common CNS origin. There were appreciable differences in the frequency of the symptoms, between children at the more socially stable schools and schools with social problems. In the latter, the frequencies of symptoms differed between Swedish and immigrant children, which was not the case in the more socially stable schools. AN - WOS:A1993LD67000013 AU - Alfven, G. DA - May DO - 10.1111/j.1651-2227.1993.tb12728.x IS - 5 N1 - Alfven, g PY - 1993 SN - 0803-5253 SP - 484-487 ST - THE COVARIATION OF COMMON PSYCHOSOMATIC SYMPTOMS AMONG CHILDREN FROM SOCIO-ECONOMICALLY DIFFERING RESIDENTIAL AREAS - AN EPIDEMIOLOGIC-STUDY T2 - Acta Paediatrica TI - THE COVARIATION OF COMMON PSYCHOSOMATIC SYMPTOMS AMONG CHILDREN FROM SOCIO-ECONOMICALLY DIFFERING RESIDENTIAL AREAS - AN EPIDEMIOLOGIC-STUDY UR - ://WOS:A1993LD67000013 VL - 82 ID - 2956 ER - TY - JOUR AB - Psychosomatic symptoms among children are believed to be commonplace. In this investigation by questionnaire, 47% of 1333 schoolchildren reported one or several symptoms, such as recurrent abdominal pain, headache, chest pains, loss of appetite and disturbances in bowel function. Coexistence of such symptoms was considerable and if a child had one of these, the probability that it would have one or more other symptoms was significantly increased. This correlation may strengthen both the suspicion that these symptoms are often psychosomatic and the idea that they have common CNS origin. There were appreciable differences in the frequency of the symptoms, between children at the more socially stable schools and schools with social problems. In the latter, the frequencies of symptoms differed between Swedish and immigrant children, which was not the case in the more socially stable schools. AD - Department of Paediatrics, Huddinge Hospital, Sweden. AN - 8518527 AU - Alfvén, G. DA - May DO - 10.1111/j.1651-2227.1993.tb12728.x DP - NLM ET - 1993/05/01 IS - 5 KW - Abdominal Pain/complications/ethnology/*psychology Adolescent Chest Pain/complications/*psychology Child Constipation/complications/psychology Diarrhea/complications/psychology Feeding and Eating Disorders/complications/psychology Female Headache/complications/*psychology Humans Male Psychophysiologic Disorders/*epidemiology/ethnology Recurrence Socioeconomic Factors Sweden/epidemiology Urban Population LA - eng N1 - Alfvén, G Journal Article Norway Acta Paediatr. 1993 May;82(5):484-7. doi: 10.1111/j.1651-2227.1993.tb12728.x. PY - 1993 SN - 0803-5253 (Print) 0803-5253 SP - 484-7 ST - The covariation of common psychosomatic symptoms among children from socio-economically differing residential areas. An epidemiological study T2 - Acta Paediatr TI - The covariation of common psychosomatic symptoms among children from socio-economically differing residential areas. An epidemiological study VL - 82 ID - 3448 ER - TY - JOUR AB - The origin of recurrent abdominal pain of "non-organic origin" is believed to be psychogenic in most cases. But the pathogenesis of the pain itself is unknown. To test the hypothesis that recurrent abdominal pain of non-organic origin is related to increased pain sensitivity in the myofascial elements of the abdominal wall itself, an investigation of pain pressure threshold of the abdominal wall, close to the umbilicus, was carried out. Altogether 140 children in the fourth school grade, approximately 11 years old, were tested for pressure pain threshold. Two groups were constituted: one without pain symptoms (no recurrent abdominal pain, chest pains or headache (n = 50)) and one with recurrent abdominal pain (n = 49). The pressure pain threshold differed significantly (p < 0.0001). To support the hypothesis that recurrent abdominal pain is a part phenomenon of a specific pattern of muscular tension and tenderness, the pressure pain threshold was tested in five other muscles, with significant results. AD - Department of Paediatrics, Huddinge Hospital, Sweden. AN - 8518526 AU - Alfvén, G. DA - May DO - 10.1111/j.1651-2227.1993.tb12727.x DP - NLM ET - 1993/05/01 IS - 5 KW - Abdominal Pain/physiopathology/*psychology Algorithms Case-Control Studies Child Female Humans Male Muscles/*physiology/physiopathology Pain Measurement/instrumentation *Pain Threshold Pressure Psychophysiologic Disorders/*physiopathology Recurrence LA - eng N1 - Alfvén, G Journal Article Norway Acta Paediatr. 1993 May;82(5):481-3. doi: 10.1111/j.1651-2227.1993.tb12727.x. PY - 1993 SN - 0803-5253 (Print) 0803-5253 SP - 481-3 ST - The pressure pain threshold (PPT) of certain muscles in children suffering from recurrent abdominal pain of non-organic origin. An algometric study T2 - Acta Paediatr TI - The pressure pain threshold (PPT) of certain muscles in children suffering from recurrent abdominal pain of non-organic origin. An algometric study VL - 82 ID - 3559 ER - TY - JOUR AB - Aim Recurrent pain of unknown origin is a major problem in children. The aim of the present review was to examine the hypothesis of negative stress as an aetiology of recurrent pain from different aspects. Methods and Results Epidemiological studies, clinical experience and hormonal data give support for such a hypothesis. Negative stress as a tentative aetiology for recurrent pain is reviewed. Stress, muscular tension, the startle reaction and its tentative relation to pain is illuminated. Deviations of hormonal secretion supporting a stress aetiology are mentioned. The role of central sensitisation for recurrent pain is discussed. Possible aetiological implications of recurrent pain as a local symptom or a general disorder are presented. Brain changes due to stress are shortly reviewed. Stress and pain in the clinic are highlighted. The importance of biological, psychological and social factors, as well as genetic elements, is discussed. Conclusion Stress elicits neurobiological mechanisms. They may lead to many neurophysiological deviances. Increase of muscle tension and neuromuscular excitability and enhanced startle reaction may be of importance for recurring pain. The identification of stress as a primary cause of recurrent pain can have huge implications for understanding signs and treatment in clinical practice. AN - WOS:000495427200006 AU - Alfven, G. AU - Grillner, S. AU - Andersson, E. DA - Dec DO - 10.1111/apa.14884 IS - 12 N1 - Alfven, G. Grillner, S. Andersson, E. 1651-2227 PY - 2019 SN - 0803-5253 SP - 2148-2156 ST - Review of childhood pain highlights the role of negative stress T2 - Acta Paediatrica TI - Review of childhood pain highlights the role of negative stress UR - ://WOS:000495427200006 VL - 108 ID - 1869 ER - TY - JOUR AB - Objectives: To investigate the frequency of irritable bowel syndrome (IBS), and symptoms compatible with this condition among male students studying in secondary schools for boys in AlJouf province of Saudi Arabia. Methods: A cross sectional study was conducted in April 2009, AlJouf province of Saudi Arabia, involving a self administered questionnaire (translated in Arabic) based on Manning and Rome II criteria for diagnosis of IBS that was distributed to 2025 students at secondary school for boys, by convenience sampling. About 86.3% (1747) completed the questionnaire. Sample size was calculated using Epi. Info 6.4, seat calculator. Results: The prevalence of IBS was 8.9 % and 9.2 % according to Manning and Rome II criteria for diagnosis of IBS respectively in the study subjects with mean age of 17.5 +/- 3 years and range of 15-23 years. The most common symptom compatible with IBS was abdominal pain or discomfort in 37.9% of our sample, followed by feeling of incomplete rectal evacuation after defecation in 32.2% of the same sample. Recurrent abdominal pain or discomfort caused increase in rates of absence from schools in 28.2% of affected students (p<0.05). There is a statistically significant association between family size and clusters of symptoms compatible with IBS (p<0.045). Conclusion: IBS is common health problem in apparently healthy males studying in secondary schools for boys in AlJouf province of Saudi Arabia. Symptoms suggestive of this condition leading to a negative impact on their quality of life measures, and school performance.. Early diagnosis and health education of this condition are imperative. AN - WOS:000296043900016 AU - Alhazmi, A. H. DA - Nov IS - 11 N1 - Alhazmi, Ahmad Homoud PY - 2011 SN - 0030-9982 SP - 1111-1115 ST - Irritable bowel syndrome in secondary school male students in AlJouf Province, North of Saudi Arabia T2 - Journal of the Pakistan Medical Association TI - Irritable bowel syndrome in secondary school male students in AlJouf Province, North of Saudi Arabia UR - ://WOS:000296043900016 VL - 61 ID - 2473 ER - TY - JOUR AB - Introduction Chronic migraine is particularly devastating. It affects school work, extracurricular activities, and quality of life, including relationships with other family members, and can also influence the mental health of both the migraineurs and family members. According to the International Classification of Headache Disorders, 3rd edition (ICHD-3), chronic migraine is defined as 15 or more headache days per month for greater than three months, where at least on eight days per month, there are features of migraine headache. Although botulinum toxin type A (BoNTA) has been proven effective for treating chronic migraine in adults, little literature exists about its use in children. Here, we present the treatment response in children with chronic migraines treated with BoNTA at our institutions Duke and State University of New York (SUNY) Upstate. Method A retrospective analysis of 30 adolescent migraineurs who met ICHD-3 criteria for chronic migraine were treated with BoNTA injection according to the standardized adult protocol. Descriptive statistics and paired t-tests were performed. A total of 185 units of botulinum toxin were injected intramuscularly per patient, as in addition to the standard 31 sites for a total of 155 units, an additional 30 units were given in areas that were felt to provide further benefit. Results Participants (n=30) were 16.5 +/- 1.83 years old. The headaches were precipitated by trauma in seven cases. All had failed standard pharmacotherapy, including amitriptyline and topiramate. An average of 2.47 +/- 1.6 BoNTA injection cycles was performed. Migraine severity decreased significantly from 7.47 +/- 1.89 on a 10-point scale to 4.34 +/- 3.02 (p<.001). Additionally, headache frequency improved from 24.4 +/- 7.49 painful days per month to 14.8 +/- 12.52 painful days per month (p<.001). One patient developed nausea related to injections; all others tolerated it well, with no side effects. Discussion BoNTA injection was a safe and effective therapy for chronic migraine in our cohort of children recalcitrant to medical therapy. Further research with multi-centered, double-blinded, randomized, placebo-controlled trials is warranted to evaluate the long-term safety and efficacy in this population. AN - WOS:000463373500002 AU - Ali, S. S. AU - Bragin, I. AU - Rende, E. AU - Mejico, L. AU - Werner, K. E. C7 - e4343 DA - Mar DO - 10.7759/cureus.4343 IS - 3 N1 - Ali, Sameer S. Bragin, Ilya Rende, Elizabeth Mejico, Luis Werner, Klaus E. 2168-8184 PY - 2019 ST - Further Evidence that Onabotulinum ,Toxin is a Viable Treatment Option for Pediatric Chronic Migraine Patients T2 - Cureus TI - Further Evidence that Onabotulinum ,Toxin is a Viable Treatment Option for Pediatric Chronic Migraine Patients UR - ://WOS:000463373500002 VL - 11 ID - 1940 ER - TY - JOUR AB - BACKGROUND: The Pain Coping Skills Training for African Americans with OsteoaRTthritis (STAART) trial is examining the effectiveness of a culturally enhanced pain coping skills training (CST) program for African Americans with osteoarthritis (OA). This disparities-focused trial aimed to reach a population with greater symptom severity and risk factors for poor pain-related outcomes than previous studies. This paper compares characteristics of STAART participants with prior studies of CST or cognitive behavioral therapy (CBT)-informed training in pain coping strategies for OA. METHODS: A literature search identified 10 prior trials of pain CST or CBT-informed pain coping training among individuals with OA. We descriptively compared characteristics of STAART participants with other studies, in 3 domains of the National Institutes of Minority Health and Health Disparities' Research Framework: Sociocultural Environment (e.g., age, education, marital status), Biological Vulnerability and Mechanisms (e.g, pain and function, body mass index), and Health Behaviors and Coping (e.g., pain catastrophizing). Means and standard deviations (SDs) or proportions were calculated for STAART participants and extracted from published manuscripts for comparator studies. RESULTS: The mean age of STAART participants, 59 years (SD = 10.3), was lower than 9 of 10 comparator studies; the proportion of individuals with some education beyond high school, 75%, was comparable to comparator studies (61-86%); and the proportion of individuals who are married or living with a partner, 42%, was lower than comparator studies (62-66%). Comparator studies had less than about 1/3 African American participants. Mean scores on the Western Ontario and McMaster Universities Osteoarthritis Index pain and function scales were higher (worse) for STAART participants than for other studies, and mean body mass index of STAART participants, 35.2 kg/m(2) (SD = 8.2), was higher than all other studies (30-34 kg/m(2)). STAART participants' mean score on the Pain Catastrophizing scale, 19.8 (SD = 12.3), was higher (worse) than other studies reporting this measure (7-17). CONCLUSIONS: Compared with prior studies with predominantly white samples, STAART participants have worse pain and function and more risk factors for negative pain-related outcomes across several domains. Given STAART participants' high mean pain catastrophizing scores, this sample may particularly benefit from the CST intervention approach. TRIAL REGISTRATION: NCT02560922. AD - Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, 3300 Thurston Bldg., CB# 7280, Chapel Hill, NC, 27599-7280, USA. kdallen@email.unc.edu. Department of Medicine, University of North Carolina at Chapel Hill, 125 MacNider Hall CB# 7005, Chapel Hill, NC, 27599, USA. kdallen@email.unc.edu. Health Services Research and Development Service, Durham VA Medical Center, Durham, NC, USA. kdallen@email.unc.edu. Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, 3300 Thurston Bldg., CB# 7280, Chapel Hill, NC, 27599-7280, USA. Department of Medicine, University of North Carolina at Chapel Hill, 125 MacNider Hall CB# 7005, Chapel Hill, NC, 27599, USA. Health Services Research and Development Service, Durham VA Medical Center, Durham, NC, USA. Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC, USA. Department of Psychology, East Carolina University, Greenville, NC, USA. Department of Psychiatry and Behavioral Science, Duke University, Durham, NC, USA. Department of Medicine, Duke University Medical Center, Durham, NC, USA. Institute for Health Research and Policy, University of Illinois at Chicago, Chicago, IL, USA. AN - 30227841 AU - Allen, K. D. AU - Arbeeva, L. AU - Cené, C. W. AU - Coffman, C. J. AU - Grimm, K. F. AU - Haley, E. AU - Keefe, F. J. AU - Nagle, C. T. AU - Oddone, E. Z. AU - Somers, T. J. AU - Watkins, Y. AU - Campbell, L. C. C2 - PMC6145122 DA - Sep 19 DO - 10.1186/s12891-018-2249-6 DP - NLM ET - 2018/09/20 IS - 1 KW - *Adaptation, Psychological Aged Arthralgia/diagnosis/ethnology/psychology/*therapy Catastrophization/diagnosis/ethnology/psychology/*therapy *Cognitive Behavioral Therapy *Culturally Competent Care Female Humans Male Middle Aged Osteoarthritis/diagnosis/ethnology/psychology/*therapy Osteoarthritis, Knee/diagnosis/ethnology/psychology/*therapy Pain Management/*methods Pain Measurement *Pain Perception Socioeconomic Factors Time Factors Treatment Outcome United States/epidemiology Health disparities Hip Knee Osteoarthritis Pain coping skills training Helsinki Declaration and was approved by the Institutional Review Boards of the University of North Carolina at Chapel Hill, Durham Veterans Affairs Medical Center, East Carolina University, and Duke University Health System. All study participants provided written informed consent. CONSENT FOR PUBLICATION: Not applicable COMPETING INTERESTS: The authors declare that they have no competing interests. PUBLISHER’S NOTE: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. LA - eng N1 - 1471-2474 Allen, Kelli D Arbeeva, Liubov Cené, Crystal W Coffman, Cynthia J Grimm, Kimberlea F Haley, Erin Keefe, Francis J Nagle, Caroline T Oddone, Eugene Z Somers, Tamara J Watkins, Yashika Campbell, Lisa C AD-1408-19519/Patient-Centered Outcomes Research Institute/ Comparative Study Journal Article Multicenter Study Randomized Controlled Trial BMC Musculoskelet Disord. 2018 Sep 19;19(1):337. doi: 10.1186/s12891-018-2249-6. PY - 2018 SN - 1471-2474 SP - 337 ST - Pain coping skills training for African Americans with osteoarthritis study: baseline participant characteristics and comparison to prior studies T2 - BMC Musculoskelet Disord TI - Pain coping skills training for African Americans with osteoarthritis study: baseline participant characteristics and comparison to prior studies VL - 19 ID - 3959 ER - TY - JOUR AB - Research consistently indicates that children with sickle cell disease (SCD) face multiple risk factors for neurocognitive impairment. Despite this, no empirical research to date has examined the impact of neurocognitive functioning on quality of life for this pediatric group. Thus, the current study aims to examine the relationship between executive functioning and quality of life in a sample of children with SCD and further explore psychosocial and family/caregiver resources as moderators of this relationship. A total of 45 children with SCD aged 8 to 16 years and their caregivers completed measures of quality of life, behavioral ratings of executive functioning, and psychosocial functioning. Hierarchical linear regression models were utilized to determine the impact of executive functioning on quality of life and further test the interaction effects of proposed moderating variables. Controlling for age, pain, and socioeconomic status (SES), executive functioning was found to significantly predict child- and parent-reported quality of life among youth with SCD. Psychosocial resources of the primary caregiver or family was not found to moderate the relationship between executive functioning and quality of life. These results provide the first empirical evidence that lower executive skills negatively predict quality of life for children with SCD, supporting clinical and research efforts which aim to establish efficacious interventions that target cognitive decrements within this pediatric population. AN - WOS:000409243600001 AU - Allen, T. M. AU - Anderson, L. M. AU - Rothman, J. A. AU - Bonner, M. J. DO - 10.1080/09297049.2016.1205011 IS - 8 N1 - Allen, Taryn M. Anderson, Lindsay M. Rothman, Jennifer A. Bonner, Melanie J. Rothman, Jennifer/0000-0003-1582-2886 1744-4136 PY - 2017 SN - 0929-7049 SP - 889-906 ST - Executive functioning and health-related quality of life in pediatric sickle cell disease T2 - Child Neuropsychology TI - Executive functioning and health-related quality of life in pediatric sickle cell disease UR - ://WOS:000409243600001 VL - 23 ID - 2120 ER - TY - JOUR AB - More than 6.5 million children in the United States, approximately 13% of all students, miss 15 or more days of school each year. The rates of chronic absenteeism vary between states, communities, and schools, with significant disparities based on income, race, and ethnicity. Chronic school absenteeism, starting as early as preschool and kindergarten, puts students at risk for poor school performance and school dropout, which in turn, put them at risk for unhealthy behaviors as adolescents and young adults as well as poor long-term health outcomes. Pediatricians and their colleagues caring for children in the medical setting have opportunities at the individual patient and/or family, practice, and population levels to promote school attendance and reduce chronic absenteeism and resulting health disparities. Although this policy statement is primarily focused on absenteeism related to students' physical and mental health, pediatricians may play a role in addressing absenteeism attributable to a wide range of factors through individual interactions with patients and their parents and through community-, state-, and federal-level advocacy. AN - WOS:000457458700053 AU - Allison, M. A. AU - Attisha, E. AU - Lerner, M. AU - De Pinto, C. D. AU - Beers, N. S. AU - Gibson, E. J. AU - Gorski, P. AU - Kjolhede, C. AU - O'Leary, S. C. AU - Schumacher, H. AU - Weiss-Harrison, A. AU - Allison, M. AU - Ancona, R. AU - Holmes, B. W. AU - Okamoto, J. AU - Young, T. AU - Chang, H. AU - Seeley, K. AU - Adkins, S. H. AU - Combe, L. AU - Johnson, V. C. AU - Joshi, S. AU - Fekaris, N. AU - Grant, L. AU - Kataoka, S. AU - Leonard, S. AU - Guinn-Jones, M. AU - Domain, S. AU - Council Sch, Hlth C7 - e20183648 DA - Feb DO - 10.1542/peds.2018-3648 IS - 2 N1 - Allison, Mandy A. Attisha, Elliott Lerner, Marc De Pinto, Cheryl Duncan Beers, Nathaniel Savio Gibson, Erica J. Gorski, Peter Kjolhede, Chris O'Leary, Sonja C. Schumacher, Heidi Weiss-Harrison, Adrienne Allison, Mandy Ancona, Richard Holmes, Breena Welch Okamoto, Jeffrey Young, Thomas Chang, Hedy Seeley, Ken Adkins, Susan Hocevar Combe, Laurie Johnson, Veda Charmaine Joshi, Shashank Fekaris, Nina Grant, Linda Kataoka, Sheryl Leonard, Sandra Guinn-Jones, Madra Domain, Stephanie 1098-4275 PY - 2019 SN - 0031-4005 ST - The Link Between School Attendance and Good Health T2 - Pediatrics TI - The Link Between School Attendance and Good Health UR - ://WOS:000457458700053 VL - 143 ID - 1955 ER - TY - JOUR AB - Purpose To describe the demographic and clinical characteristics of children who presented with open femur fractures. Methods A retrospective chart review of all children treated for open femur fractures at the McGill University Health Center between 1980 and 2009 was conducted. Thirty-seven patients (28 males and 9 females) were identified. Union was determined clinically by the absence of pain, tenderness to palpation and crepitus with motion. Complications were reported. Results The mean age of the patients was 11.5 years (range 2.8-18.1 years). The mechanism of injury involved motor vehicle-related injuries in 70% of cases. There were 13 Grade I, 15 Grade II and 9 Grade III fractures. The treatment involved traction and hip spica in 11 patients, external fixator in nine patients, intramedullary nailing in seven patients, open reduction and internal fixation in six patients, and traction and an ischial weight bearing brace in four patients. Average time to union was 5.1 months (range 1.5-14.4 months). Infections occurred in ten patients, nine had delayed unions, two developed malunions, four had a refracture and four patients developed a limb length discrepancy[2 cm. Conclusions Open fractures of the femur are often accompanied by associated injuries, indicating the importance of early and comprehensive treatment. Treatment may include hip spica application in school-age children and solid intramedullary nails in adolescents. In children with multiple injuries, specifically those with higher fracture grades, treatment with an external fixator provides immediate stability of the fracture and allows early mobilization and ease of management of associated injuries. AN - WOS:000215405300005 AU - Allison, P. AU - Dahan-Oliel, N. AU - Jando, V. T. AU - Yang, S. S. AU - Hamdy, R. C. DA - Apr DO - 10.1007/s11832-011-0334-6 IS - 2 N1 - Allison, Patrick Dahan-Oliel, Noemi Jando, Victor T. Yang, Stephen Su Hamdy, Reggie C. Yang, Stephen/M-8177-2019 Yang, Stephen/0000-0003-3859-5110 1863-2548 PY - 2011 SN - 1863-2521 SP - 101-108 ST - Open fractures of the femur in children: analysis of various treatment methods T2 - Journal of Childrens Orthopaedics TI - Open fractures of the femur in children: analysis of various treatment methods UR - ://WOS:000215405300005 VL - 5 ID - 2504 ER - TY - JOUR AN - WOS:000541963200494 AU - Alsaggaf, F. AU - Coyne, I. DA - Jun DO - 10.1136/archdischild-2019-epa.493 N1 - Alsaggaf, Fatimah Coyne, Imelda 1468-2044 3 PY - 2019 SN - 0003-9888 SP - A211-A212 ST - IMPACT OF CHRONIC PAIN ON ADOLESCENTS' SCHOOL FUNCTIONING: A SYSTEMATIC REVIEW T2 - Archives of Disease in Childhood TI - IMPACT OF CHRONIC PAIN ON ADOLESCENTS' SCHOOL FUNCTIONING: A SYSTEMATIC REVIEW UR - ://WOS:000541963200494 VL - 104 ID - 1916 ER - TY - JOUR AB - Background: Recurrent abdominal pain (RAP) is a common complaint in children. Significant portion of them are of functional origin. This study aimed to assess the prevalence of abdominal pain-predominant functional gastrointestinal disorder (FGID) and its types in Jordanian school children. Methods: This is a school-based survey at south Jordan. Information using the self-reporting form of the Questionnaire on Pediatric Gastrointestinal Symptoms-Rome III Version (QPGS-RIII) - the official Arabic translation - was collected. Classes from academic years (grades) 6 - 8 were selected. SPSS Statistical Package Version 17 (IBM, Armonk, NY, USA) was used. Categorical data were analyzed using Fisher's exact test, and continuous data were analyzed using t-test. P < 0.05 was considered significant. Results: Five hundred questionnaires were distributed, and 454 returned answered (91%). Two hundred twenty-nine (50.8%) were males. The average age of participants was 12.7 years (11 - 15 years). One hundred sixteen (25.7%) had abdominal pain-predominant FGID. Seventy-nine (68%) of them were females. Forty-seven (10.6%) had irritable bowel syndrome (IBS). Thirty-six (8%), 17 (3.8%), 11 (2.4%) and five (1.1%) had abdominal migraine, functional abdominal pain, functional abdominal pain syndrome and functional dyspepsia, respectively. Conclusion: Abdominal pain-predominant FGID has become a major health issue in Jordanian children. One of four children between the ages of 11 and 15 years exhibits at least one abdominal pain-predominant FGID. The most common form of abdominal pain-predominant FGID in our children was IBS. Females are affected more often than males. Intestinal and extra-intestinal symptoms are seen regularly with abdominal pain-predominant FGIDs. AN - WOS:000215447500005 AU - Altamimi, E. M. AU - Al-Safadi, M. H. DA - Dec DO - 10.14740/gr627w IS - 5-6 N1 - Altamimi, Eyad M. Al-Safadi, Mohammad H. 1918-2813 PY - 2014 SN - 1918-2805 SP - 137-142 ST - Abdominal Pain-Predominant Functional Gastrointestinal Disorders in Jordanian School Children T2 - Gastroenterology Research TI - Abdominal Pain-Predominant Functional Gastrointestinal Disorders in Jordanian School Children UR - ://WOS:000215447500005 VL - 7 ID - 2274 ER - TY - JOUR AB - This descriptive, correlational study examined fatigue and potential biological and behavioral correlates in adolescents and young adults with sickle cell disease. Sixty adolescents and young adults with sickle cell disease completed the Brief Fatigue Inventory, Multidimensional Fatigue Symptom Inventory-Short Form, Patient Reported Outcomes Measurement Information System (PROMIS) fatigue short form and measures of pain, sleep quality, anxiety, depressive mood, stress, disease severity, and quality of life. Blood samples were obtained for hemoglobin and cytokines. Fatigue scores were mostly moderate in severity. Fatigue interfered to a moderate degree with daily activities and correlated significantly with pain, sleep quality, state and trait anxiety, depressive mood, stress, and quality of life. Fatigue was correlated with hemoglobin on the PROMIS measure. Fatigue was not correlated with cytokines or age, nor differed by disease severity. Fatigue was common in these adolescents and young adults, interfered with daily activities such as school, work and exercise, and significantly correlated with several potentially modifiable factors. As life expectancy increases in sickle cell disease, research is needed to test interventions to reduce fatigue. AD - 1Virginia Commonwealth University, Richmond, VA, USA. AN - 24378816 AU - Ameringer, S. AU - Elswick, R. K., Jr. AU - Smith, W. C2 - PMC3982311 C6 - NIHMS563570 DA - Jan-Feb DO - 10.1177/1043454213514632 DP - NLM ET - 2014/01/01 IS - 1 KW - Adolescent Adult Anemia, Sickle Cell/*physiopathology/psychology Cross-Sectional Studies *Fatigue Female Humans Male *Quality of Life Severity of Illness Index Young Adult adolescents and young adults fatigue pain quality of life sickle cell disease LA - eng N1 - 1532-8457 Ameringer, Suzanne Elswick, R K Jr Smith, Wally U54 HL090516/HL/NHLBI NIH HHS/United States P30 NR011403/NR/NINR NIH HHS/United States UL1RR031990/RR/NCRR NIH HHS/United States 1 R01 HL 64122/HL/NHLBI NIH HHS/United States 1 U54 HL090516/HL/NHLBI NIH HHS/United States 1 U10 HL083732/HL/NHLBI NIH HHS/United States Journal Article Research Support, N.I.H., Extramural J Pediatr Oncol Nurs. 2014 Jan-Feb;31(1):6-17. doi: 10.1177/1043454213514632. Epub 2013 Dec 30. PY - 2014 SN - 1043-4542 (Print) 1043-4542 SP - 6-17 ST - Fatigue in adolescents and young adults with sickle cell disease: biological and behavioral correlates and health-related quality of life T2 - J Pediatr Oncol Nurs TI - Fatigue in adolescents and young adults with sickle cell disease: biological and behavioral correlates and health-related quality of life VL - 31 ID - 3986 ER - TY - JOUR AB - Objectives To better understand factors associated with the development and persistence of habit cough and to report use of self-hyponis for this condition. Study design A retrospective chart review was performed for 56 children and adolescents with habit cough. Interested patients were instructed in self-hypnosis for relaxation and to help ignore the cough-triggering sensation. Results The patients mean age was 10.7 years. The cough was triggered by upper respiratory infections in 59%, asthma in 13%, exercise in 5%, and eating in 4%. Onset of the cough occurred as early as 2 years, and its average duration was 13 months (range, 2 weeks to 7 years). There was a high incidence of abdominal pain and irritable bowel syndrome in the 50% of the patients who missed more than 1 week of school because of their cough. Among the 51 patients who used hypnosis, the cough resolved during or immediately after the initial hypnosis instruction session in 78% and within 1 month in an additional 12%.. Conclusions Habit cough is triggered by various physiologic conditions, related frequently to other diagnoses, and it is associated with significant school absence. Self-hypnosis offers a safe efficient treatment. AN - WOS:000188925800018 AU - Anbar, R. D. AU - Hall, H. R. DA - Feb DO - 10.1016/j.jpeds.2003.10.041 IS - 2 N1 - Anbar, RD Hall, HR 1097-6833 PY - 2004 SN - 0022-3476 SP - 213-217 ST - Childhood habit cough treated with self-hypnosis T2 - Journal of Pediatrics TI - Childhood habit cough treated with self-hypnosis UR - ://WOS:000188925800018 VL - 144 ID - 2797 ER - TY - JOUR AB - In a cross-sectional study of 2684 males from a range of occupations the prevalence rate for back pain was 20% (11% disc disease and 9% undetermined pain) and about half of these had pain related to the lower back with the remainder being located in the dorsoscapular or cervical regions. Follow up study of a cohort of 1249 of these workers over a two year period indicated that the incidence rate of low back pain in that group was about 1% per annum. When sickness absence certificates were studied the annual absence from back pain (all sites) was 1323 days per thousand employees. However, when confirmation was obtained from general practitioners about non-specific rheumatic diagnoses this figure rose to 1707 days. The prevalence of disc disease is higher among those engaged in heavy rather than among those in light work, and also among those required to adopt a chronic stooping posture at the place of work. A device designed to record lumbar EMG, antero-posterior and lateral posture of the lumbar spine and intra-abdominal pressure designed to be used in work places over a complete shift is described and traces obtained under laboratory conditions are presented. AD - Department of Community Medicine, United Medical School, Guy's Campus, London. AN - 2968632 AU - Anderson, J. A. AU - Otun, E. O. AU - Sweetman, B. J. DA - Jan-Jun DO - 10.1515/reveh.1987.7.1-2.121 DP - NLM ET - 1987/01/01 IS - 1-2 KW - Absenteeism Adolescent Adult Aged Back Pain/*etiology/prevention & control Cross-Sectional Studies Electromyography/instrumentation Humans Male Middle Aged Occupational Diseases/*etiology/prevention & control Risk Factors LA - eng N1 - Anderson, J A Otun, E O Sweetman, B J Journal Article Research Support, Non-U.S. Gov't Review Germany Rev Environ Health. 1987 Jan-Jun;7(1-2):121-60. doi: 10.1515/reveh.1987.7.1-2.121. PY - 1987 SN - 0048-7554 (Print) 0048-7554 SP - 121-60 ST - Occupational hazards and low back pain T2 - Rev Environ Health TI - Occupational hazards and low back pain VL - 7 ID - 3651 ER - TY - JOUR AB - Children with sickle cell disease (SCD) report fatigue in addition to acute and chronic pain, which can decrease overall health-related quality of life (HRQL). The primary objective of the current study was to investigate the relationship between fatigue and HRQL. Given limited prior research, secondary objectives included investigation of associations between fatigue and functional outcomes, including child neurocognitive and social-emotional functioning. Children aged 8 to 16 years (N=32) and a caregiver completed measures of fatigue, HRQL, pain, and neurocognitive and social-emotional functioning. Controlling for pain and number of SCD-related hospitalizations, hierarchical linear regression models were used to determine the impact of child-reported and parent-reported fatigue on child HRQL. Correlational analyses were used to explore the relationship between fatigue and additional child outcomes. Data indicated that children with SCD experience clinically relevant levels of fatigue, which independently predicts lower HRQL. Fatigue was also associated with lower working memory, executive functioning, and higher levels of internalizing symptoms. Given its observed impact on HRQL and relationship to functional outcomes, fatigue may be an important target of clinical, home, or school interventions. This practice may attenuate the burden of fatigue in these patients, and in turn, help improve the quality of life of children living with SCD. AN - WOS:000364330200002 AU - Anderson, L. M. AU - Allen, T. M. AU - Thornburg, C. D. AU - Bonner, M. J. DA - Nov DO - 10.1097/mph.0000000000000431 IS - 8 N1 - Anderson, Lindsay M. Allen, Taryn M. Thornburg, Courtney D. Bonner, Melanie J. 1536-3678 PY - 2015 SN - 1077-4114 SP - 584-589 ST - Fatigue in Children With Sickle Cell Disease: Association With Neurocognitive and Social-Emotional Functioning and Quality of Life T2 - Journal of Pediatric Hematology Oncology TI - Fatigue in Children With Sickle Cell Disease: Association With Neurocognitive and Social-Emotional Functioning and Quality of Life UR - ://WOS:000364330200002 VL - 37 ID - 2212 ER - TY - JOUR AB - PURPOSE: To compare the effectiveness of pain neuroscience education (PNE) and neck/shoulder exercises with no intervention in adolescents with chronic idiopathic neck pain (CINP). METHODS: Forty-three adolescents with CINP were randomly allocated to receive PNE and shoulder/neck exercises (n = 21) or no intervention (n = 22). Data on pain intensity, neck flexor and extensor muscles endurance, scapular stabilizers endurance, pain catastrophizing, anxiety, and knowledge of pain neurophysiology were collected. Measurements were taken before and after the intervention. RESULTS: All participants completed the study. Analysis using ANCOVA revealed a significant increase in the neck extensors endurance capacity (adjusted mean ± SE change = + 47.5 ± 13.5 s versus +14.2 ± 13.1 s) and knowledge of pain neurophysiology (adjusted mean ± SE change = + 9.8 ± 3.2 versus -0.6 ± 0.6) in the group receiving the intervention. A higher mean decrease in pain intensity, pain catastrophizing and anxiety and a higher mean increase in the scapular stabilizers endurance capacity were also found in the intervention group, but differences did not reach statistical significance. CONCLUSIONS: Results suggest a potential benefit of PNE and exercise for adolescents with CINP. Further studies with larger sample sizes are needed. AU - Andias, Rosa AU - Neto, Maritza AU - Silva, Anabela G. DA - 2018/09// DO - 10.1080/09593985.2018.1423590 DP - PubMed IS - 9 J2 - Physiother Theory Pract KW - Adolescent Adolescent Behavior adolescents Anxiety Catastrophization Chronic Pain Combined Modality Therapy Education exercise Exercise Therapy Exercise Tolerance Female Health Knowledge, Attitudes, Practice Humans intervention Male Muscle Strength Neck Muscles neck pain Neurosciences Patient Education as Topic Physical Endurance Portugal School Health Services Time Factors Treatment Outcome LA - eng PY - 2018 SN - 1532-5040 SP - 682-691 ST - The effects of pain neuroscience education and exercise on pain, muscle endurance, catastrophizing and anxiety in adolescents with chronic idiopathic neck pain T2 - Physiotherapy Theory and Practice TI - The effects of pain neuroscience education and exercise on pain, muscle endurance, catastrophizing and anxiety in adolescents with chronic idiopathic neck pain: a school-based pilot, randomized and controlled study UR - http://www.ncbi.nlm.nih.gov/pubmed/29319386 VL - 34 ID - 55 ER - TY - JOUR AB - OBJECTIVES: To investigate the relative importance of common physical and mental disorders with regard to the number of days out-of-role (DOR; number of days for which a person is completely unable to work or carry out normal activities because of health problems) in a population-based sample of adults in the São Paulo Metropolitan Area, Brazil. METHODS: The São Paulo Megacity Mental Health Survey was administered during face-to-face interviews with 2,942 adult household residents. The presence of 8 chronic physical disorders and 3 classes of mental disorders (mood, anxiety, and substance use disorders) was assessed for the previous year along with the number of days in the previous month for which each respondent was completely unable to work or carry out normal daily activities due to health problems. Using multiple regression analysis, we examined the associations of the disorders and their comorbidities with the number of days out-of-role while controlling for socio-demographic variables. Both individual-level and population-level associations were assessed. RESULTS: A total of 13.1% of the respondents reported 1 or more days out-of-role in the previous month, with an annual median of 41.4 days out-of-role. The disorders considered in this study accounted for 71.7% of all DOR; the disorders that caused the greatest number of DOR at the individual-level were digestive (22.6), mood (19.9), substance use (15.0), chronic pain (16.5), and anxiety (14.0) disorders. The disorders associated with the highest population-attributable DOR were chronic pain (35.2%), mood (16.5%), and anxiety (15.0%) disorders. CONCLUSIONS: Because pain, anxiety, and mood disorders have high effects at both the individual and societal levels, targeted interventions to reduce the impairments associated with these disorders have the highest potential to reduce the societal burdens of chronic illness in the São Paulo Metropolitan Area. AD - Section of Psychiatric Epidemiology - LIM 23, Department and Institute of Psychiatry, Faculdade de Medicina, Universidade de São Paulo, São PauloSP, Brazil. AN - 24270949 AU - Andrade, L. H. AU - Baptista, M. C. AU - Alonso, J. AU - Petukhova, M. AU - Bruffaerts, R. AU - Kessler, R. C. AU - Silveira, C. M. AU - Siu, E. R. AU - Wang, Y. P. AU - Viana, M. C. C2 - PMC3812560 DA - Nov DO - 10.6061/clinics/2013(11)02 DP - NLM ET - 2013/11/26 IS - 11 KW - *Absenteeism *Activities of Daily Living Adolescent Adult Brazil/epidemiology Chronic Pain/epidemiology Comorbidity Female Health Surveys/*statistics & numerical data Humans Male Mental Disorders/*epidemiology Mental Health/statistics & numerical data Prevalence Socioeconomic Factors Time Factors Urban Population/statistics & numerical data World Health Organization Young Adult LA - eng N1 - 1980-5322 Andrade, Laura Helena Baptista, Marcos C Alonso, Jordi Petukhova, Maria Bruffaerts, Ronny Kessler, Ronald C Silveira, Camila M Siu, Erica R Wang, Yuan-Pang Viana, Maria Carmen R01 DA016558/DA/NIDA NIH HHS/United States R01MH070884/MH/NIMH NIH HHS/United States R01-MH069864/MH/NIMH NIH HHS/United States R03-TW006481/TW/FIC NIH HHS/United States R13-MH066849/MH/NIMH NIH HHS/United States Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Clinics (Sao Paulo). 2013 Nov;68(11):1392-9. doi: 10.6061/clinics/2013(11)02. PY - 2013 SN - 1807-5932 (Print) 1807-5932 SP - 1392-9 ST - Days out-of-role due to common physical and mental health problems: results from the São Paulo Megacity Mental Health Survey, Brazil T2 - Clinics (Sao Paulo) TI - Days out-of-role due to common physical and mental health problems: results from the São Paulo Megacity Mental Health Survey, Brazil VL - 68 ID - 3335 ER - TY - JOUR AB - PURPOSE: Cognitive behavioral therapy (CBT)-based programs delivered by trained community members could improve functioning and pain in individuals who lack access to such programs. We tested the effectiveness of a peer-delivered diabetes self-management program integrating CBT principles in improving physical activity, functional status, pain, quality of life (QOL), and health outcomes in individuals with diabetes and chronic pain. METHODS: In this community-based, cluster-randomized controlled trial, intervention participants received a 3-month, peer-delivered, telephone-administered program. Attention control participants received a peer-delivered general health advice program. Outcomes were changes in functional status and pain (Western Ontario and McMaster Universities Osteoarthritis Index), QOL (Short Form 12), and physiologic measures (hemoglobin A(1c), systolic blood pressure, body mass index); physical activity was the explanatory outcome. RESULTS: Of 195 participants with follow-up data, 80% were women, 96% African Americans, 74% had annual income <$20,000, and 64% had high school education or less. At follow-up, compared with controls, intervention participants had greater improvement in functional status (-10 ± 13 vs -5 ± 18, P = .002), pain (-10.5 ± 19 vs -4.8 ± 21, P = .01), and QOL (4.8 ± 8.8 vs 3.8 ± 8.8, P = .001). Physiologic measures did not change significantly in either group. At 3 months, a greater proportion of intervention than control participants reported no pain or did other forms of exercise when pain prevented them from walking for exercise. CONCLUSION: This peer-delivered CBT-based intervention improved functioning, pain, QOL, and self-reported physical activity despite pain in individuals with diabetes and chronic pain. Trained community members can deliver effective CBT-based interventions in rural and under-resourced communities. AD - Department of Kinesiology, University of Wisconsin-Madison, Madison, Wisconsin. Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama. Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama. Department of Medicine, Weill Cornell Medicine, New York, New York mms9024@med.cornell.edu. AN - 31937528 AU - Andreae, S. J. AU - Andreae, L. J. AU - Richman, J. S. AU - Cherrington, A. L. AU - Safford, M. M. C2 - PMC7227468 DA - Jan DO - 10.1370/afm.2469 DP - NLM ET - 2020/01/16 IS - 1 KW - Aged Chronic Pain Cluster Analysis Cognitive Behavioral Therapy/*methods Diabetes Mellitus/psychology/*therapy Female Humans Male *Mentoring Middle Aged Pain Management/psychology Physical Functional Performance Quality of Life Rural Population Self-Management/*education *chronic pain *cognitive behavioral therapy *community health workers *community peer coaches *diabetes LA - eng N1 - 1544-1717 Andreae, Susan J Andreae, Lynn J Richman, Joshua S Cherrington, Andrea L Safford, Monika M R18 HS019239/HS/AHRQ HHS/United States Journal Article Multicenter Study Randomized Controlled Trial Research Support, U.S. Gov't, P.H.S. Ann Fam Med. 2020 Jan;18(1):15-23. doi: 10.1370/afm.2469. PY - 2020 SN - 1544-1709 (Print) 1544-1709 SP - 15-23 ST - Peer-Delivered Cognitive Behavioral Training to Improve Functioning in Patients With Diabetes: A Cluster-Randomized Trial T2 - Ann Fam Med TI - Peer-Delivered Cognitive Behavioral Training to Improve Functioning in Patients With Diabetes: A Cluster-Randomized Trial VL - 18 ID - 3041 ER - TY - JOUR AB - In childhood and adolescence, migraine is the main primary headache. This diagnosis is largely underestimated and misdiagnosed in the pediatric population. Because of the lack of specific biologic markers, specific investigation tools or brain imaging techniques, these clinical entities are too often considered to be a psychological illness. Migraine is a severe headache evolving by stereotyped attacks associated with marked digestive symptoms (nausea and vomiting); throbbing pain and sensitivity to sound or light are common symptoms; the attack is sometimes preceded by a visual or sensory aura. During attacks, pain intensity is severe; most of the children have to lie down. Abdominal pain is frequently associated, rest brings relief and sleep often ends the attack. The prevalence of migraine varies between 5 percent and 10 percent in childhood. In children, the duration of the headache is quite often shorter than in adults; it is more often frontal and bilateral (2/3 of cases) than one-sided. Migraine is a disabling illness: children with migraine miss more school days in a school year than their matched controls. Migraine episodes are frequently triggered by several factors: emotional stress (school pressure, vexation, excitement: upset), hypoglycemia, lack of sleep or excess (week end migraine), sensorial stimulation (loud noise, bright light, strong odor, heat or cold..), sympathetic stimulation (sports, physical exercise). Treatment must be given early at onset of attacks; oral ibuprofen (10 mg/kg) is recommended. If the oral route in not available because of nausea or vomiting, the rectal or nasal routes can be used. Triptan can be prescribed (body weight above 30 kg) when NSAID (prescribed at right dose and time) fail to abort the attack. Non-drug treatments (relaxation training, self hypnosis, biofeedback) have shown to have good efficacy as prophylactic measures. Daily prophylactic drug treatments are prescribed in second line after failure of non-drug treatment. AN - WOS:000230344900016 AU - Annequin, D. DA - Jul IS - 6-7 N1 - Annequin, D Annequin, Daniel/0000-0001-6425-4016 2213-0004 PY - 2005 SN - 0035-3787 SP - 687-688 ST - Migraine in childhood T2 - Revue Neurologique TI - Migraine in childhood UR - ://WOS:000230344900016 VL - 161 ID - 2759 ER - TY - JOUR AB - In childhood and adolescence, migraine is the main essential chronic headache. This diagnosis is extensively underestimated and misdiagnosed in pediatric population. Lacks of specific biologic marker, specific investigation or brain imaging reduce these clinical entities too often to a psychological illness. Migraine is a severe headache evolving by stereotyped crises associated with marked digestive symptoms (nausea and vomiting); throbbing pain, sensitivity to sound, light are usual symptoms; the attack is sometimes preceded by a visual or sensory aura. During attacks, pain intensity is severe, most of children must lie down. Abdominal pain is frequently associated rest brings relief and sleep ends often the attack The prevalence of the migraine varies between 5p.100 and 10p.100 in childhood. At childhood, headache duration is quite often shorter than in adult population, it is more often frontal, bilateral (2/3 of cases) that one-sided. Migraine is a disabling illness: children with migraine lost more school days in a school year, than a matched control group. Migraine episodes are frequently triggered by several factors: emotional stress (school pressure, vexation, excitement upset), hypoglycemia, lack of sleep or excess (week end migraine), sensorial stimulation (loud noise, bright light, strong odor, heat or cold...), sympathetic stimulation (sport, physical exercise). Attack treatments must be given at the early beginning of the crisis; oral dose of ibuprofen (10mg/kg) is recommended. If the oral route in not available when nausea or vomiting occurs, the rectal or nasal routes have then to be used. Non pharmacological treatments (biofeedback and interventions combining progressive muscle relaxation) have shown to have good efficacy as prophylactic measure. Daily prophylactic pharmacological treatments are prescribed in second line after failure of non-pharmacological treatment. AN - WOS:000166543700011 AU - Annequin, D. AU - Dumas, C. AU - Tourniaire, B. AU - Massiou, H. N1 - Annequin, D Dumas, C Tourniaire, B Massiou, H 6th Congress on Therapeutics and Neurology on Headaches Dec 03-04, 1999 Paris, france 4 PY - 2000 SN - 0035-3787 SP - 68-74 ST - Migraine and chronic headache in children T2 - Revue Neurologique TI - Migraine and chronic headache in children UR - ://WOS:000166543700011 VL - 156 ID - 2872 ER - TY - JOUR AB - In childhood and adolescence, migraine is the main primary headache. This diagnosis is extensively underestimated and misdiagnosed in pediatric population. Lacks of specific biologic marker, specific investigation or brain imaging reduce these clinical entities too often to a psychological illness. Migraine is a severe headache evolving by stereotyped crises associated with marked digestive symptoms (nausea and vomiting); throbbing pain, sensitivity to sound, light are usual symptoms; the attack is sometimes preceded by a visual or sensory aura. During attacks, pain intensity is severe, most of children must lie down. Abdominal pain is frequently associated, rest brings relief and sleep ends often the attack. The prevalence of the migraine varies between 5% and 10% in childhood. At childhood, headache duration is quite often shorter than in adult population, it is more often frontal, bilateral (2/3 of cases) that one-sided. Migraine is a disabling illness: children with migraine lost more school days in a school year, than a matched control group. Migraine episodes are frequently triggered by several factors: emotional stress (school pressure, vexation, excitement: upset), hypoglycemia, lack of sleep or excess (week end migraine), sensorial stimulation (loud noise, bright light, strong odor, heat or cold...), sympathetic stimulation (sport, physical exercise). Attack treatments must be given at the early beginning of the crisis; oral dose of ibuprofen (10 mg/kg) is recommended. If the oral route is not available when nausea or vomiting occurs, the rectal or nasal routes have then to be used. Non pharmacological treatments (relaxation training, self hypnosis, biofeedback) have shown to have good efficacy as prophylactic measure. Daily prophylactic pharmacological treatments are prescribed in second line after failure of non-pharmacological treatment. (c) 2005 Elsevier SAS. Tous droits reserves. AN - WOS:000229455400029 AU - Annequin, D. AU - Tourniaire, B. DA - May DO - 10.1016/j.arcped.2004.07.007 IS - 5 N1 - Annequin, D Tourniaire, B Annequin, Daniel/0000-0001-6425-4016 1769-664x PY - 2005 SN - 0929-693X SP - 624-629 ST - Migraine and headache in childhood T2 - Archives De Pediatrie TI - Migraine and headache in childhood UR - ://WOS:000229455400029 VL - 12 ID - 2765 ER - TY - JOUR AB - Although migraine is the main chronic headache in childhood and adolescence, it remains extensively misdiagnosed. Schematically, migraine is a severe headache evolving by stereotyped attacks frequently associated with marked digestive symptoms (nausea, vomiting, abdominal pain). Throbbing pain, sensitivity to sound, and light (and sometimes odors) are frequent additional symptoms. The attack is sometimes preceded by a visual or sensory aura. Rest brings relief, and sleep often ends the attack. Childhood migraine prevalence varies between 5 and 10%. Migraine episodes are frequently triggered by several factors: emotional stress (school pressure, vexation, excitement, upset), hypoglycemia, lack or excess of sleep (weekend migraine), sensory stimulation (loud noise, bright light, strong odor, heat or cold, etc.), sympathetic stimulation (sport, physical exercise). Attack treatments must be given at an early stage, oral ibuprofen (10 mg/kg) being particularly recommended. If the oral route is not available because of nausea or vomiting, rectal or nasal routes have then to be used. Non-pharmacological treatments (biofeedback and interventions combining progressive muscle relaxation) have demonstrated good efficacy as prophylactic measures. Daily prophylactic pharmacological treatments are prescribed as the second line after failure of non-pharmacological treatments. AD - Unité fonctionnelle d'analgésie pédiatrique, hôpital d'enfants Armand-Tousseau, Paris, France. AN - 11028209 AU - Annequin, D. AU - Tourniaire, B. AU - Dumas, C. DA - Sep DO - 10.1016/s0929-693x(00)90016-2 DP - NLM ET - 2000/10/12 IS - 9 KW - Abdominal Pain/etiology Anti-Inflammatory Agents, Non-Steroidal/therapeutic use Child Child Welfare Diagnosis, Differential Humans Ibuprofen/therapeutic use Incidence Migraine Disorders/diagnosis/epidemiology/*etiology Nausea/etiology Stress, Psychological Vomiting/etiology LA - fre N1 - Annequin, D Tourniaire, B Dumas, C English Abstract Journal Article France Arch Pediatr. 2000 Sep;7(9):985-90. doi: 10.1016/s0929-693x(00)90016-2. OP - La migraine, pathologie méconnue chez l'enfant. PY - 2000 SN - 0929-693X (Print) 0929-693x SP - 985-90 ST - [Migraine, misunderstood pathology in children] T2 - Arch Pediatr TI - [Migraine, misunderstood pathology in children] VL - 7 ID - 3569 ER - TY - JOUR AB - In all forms of rheumatic disease in childhood, early and accurate diagnosis is essential. The aims of therapy in juvenile arthritis are pain relief and the preservation of joint function while maintaining normal growth and psychological development. As management is complex it will require a coordinated, multi-disciplinary team in which good communication between all members is a priority. Many families will need some form of counselling, whether it be from a social worker, the paediatrician involved, or a psychologist. This is particularly important in adolescence, whether the disease has commenced at this time or whether the child has gone into adolescence with a chronic illness. AN - WOS:A1994PB89700021 AU - Ansell, B. M. DA - Sep-Oct N1 - Ansell, bm 2nd European Conference on Pediatric Autoimmune and Rheumatic Diseases Sep 07-10, 1994 Pavia, italy 10 PY - 1994 SN - 0392-856X SP - S113-S116 ST - HOW SHOULD PEDIATRIC RHEUMATOLOGY BE DELIVERED T2 - Clinical and Experimental Rheumatology TI - HOW SHOULD PEDIATRIC RHEUMATOLOGY BE DELIVERED UR - ://WOS:A1994PB89700021 VL - 12 ID - 2947 ER - TY - JOUR AB - Objective To determine the extent to which parental perceptions of child vulnerability predict school and social adjustment in children with chronic illness. Methods Sixty-nine child-parent dyads were recruited from pediatric rheumatology and pulmonary clinics. Parents completed a self-report measure of parental perceptions of child vulnerability. Children completed measures of social adjustment. Parents also provided written permission to obtain school attendance records. Physicians provided a global assessment of children's disease severity. Results Increased parental perceptions of child vulnerability were related to increased social anxiety in children, even after controlling for child age and disease severity. Lower levels of parental education related to both increased perceptions of child vulnerability and increased school absences. Conclusions Health providers should assess parental beliefs and parenting practices in assessing the adjustment of children with chronic illness. Moreover, interventions aimed at enhancing child adjustment to chronic illness might best target parents as well as children. AN - WOS:000182079000005 AU - Anthony, K. K. AU - Gil, K. M. AU - Schanberg, L. E. DA - Apr-May DO - 10.1093/jpepsy/jsg005 IS - 3 N1 - Anthony, KK Gil, KM Schanberg, LE PY - 2003 SN - 0146-8693 SP - 185-190 ST - Brief report: Parental perceptions of child vulnerability in children with chronic illness T2 - Journal of Pediatric Psychology TI - Brief report: Parental perceptions of child vulnerability in children with chronic illness UR - ://WOS:000182079000005 VL - 28 ID - 2812 ER - TY - JOUR AU - Apley, J. AU - Naish, N. DA - 1958/04// DO - 10.1136/adc.33.168.165 DP - PubMed IS - 168 J2 - Arch Dis Child KW - Abdomen ABDOMEN/diseases Abdominal Pain Child Disease Gastrointestinal Diseases Humans LA - eng PY - 1958 SN - 0003-9888 SP - 165-170 ST - Recurrent abdominal pains T2 - Archives of Disease in Childhood TI - Recurrent abdominal pains: a field survey of 1,000 school children UR - http://www.ncbi.nlm.nih.gov/pubmed/13534750 VL - 33 ID - 92 ER - TY - CHAP AB - OBJECTIVE: To identify and summarize evidence from empirical studies relating to the cost of care and the economic impact of chronic headache. SEARCH STRATEGY: We used a strategy combining the MeSH term "headache" (exploded) with terms and text words pertaining to cost and resource utilization to search the MEDLINE, HealthStar, and CINAHL databases for relevant studies published between January 1966 and December 1996. Other computerized bibliographic databases, textbooks, and experts were also utilized. SELECTION CRITERIA: We considered full reports of original empirical research, published in English, which concerned an adult (non-pediatric) subject population suffering from primary headache (i.e., not traumatic, post-lumbar puncture, or other secondary headaches), reported data relevant to the economic impact of chronic headache on medical resource utilization or work loss, and met minimal methodological criteria related to the validity of cost or utilization measures. DATA COLLECTION AND ANALYSIS: From studies of patients with primary headache, data were collected on: rates and predictors of headache-related and total health care provider consultation, emergency department utilization, hospitalization, prescription and non-prescription drug use, and work loss and disability. Data were annualized when necessary to make results of different studies more comparable. MAIN RESULTS: Of over 400 citations identified, 126 appeared to meet screening criteria, and 35 met all criteria and were included in this review. While between 56% and 91% of chronic headache sufferers seek the care of a health care provider, only one-third report having received a diagnosis of their condition. While most patients with migraine consult a health care provider at some point, most do not continue to seek medical care. Relatively fewer patients with tension-type headache seek medical care. A small sub-population of chronic headache sufferers accounts for a high proportion of provider consultations, emergency department visits, and prescription drug claims. The vast majority of headache sufferers have used drugs to treat their headaches at some time. Non-prescription drugs are used more often than prescription drugs. Patients with more severe headache symptoms are both more likely to consult a health care provider about their headaches and more likely to use prescription medications. Use of prescription drugs for headache increases with age and is higher among women than men. About two-thirds of patients who try prescription medications do not continue to use them, citing the availability of effective non-prescription drugs, unwanted side-effects, and inadequate relief among the reasons for discontinuing prescription drug use. Rates of absenteeism due to headache of 2 to 4.3 days per year were reported in employee and community studies, while higher rates, ranging from 14.3 to 61 days per year, were observed in two studies conducted in clinical settings. These average figures obscure the fact that while many to most patients miss no days of work or school, a relatively small proportion of subjects accounts for many missed days. While headache does cause a large number of absences from work, it appears that many headache sufferers stay on the job, functioning with significantly reduced effectiveness, when they have a headache. CONCLUSIONS: Chronic headache sufferers represent a diverse population which is difficult to study. Population-based studies suggest that many headache sufferers do not seek medical care for their headaches and do not use prescription drugs to treat them. Studies conducted among headache patients in clinical settings suggest that these patients have more severe headache symptoms, use more prescriptions drugs, and are heavier users of medical resources. Data from both types of studies must be considered if the comprehensive cost of chronic headache is to be estimated. AD - Center for Clinical Health Policy Research, Duke University AN - 20734516 AU - Archibald, N. AU - Lipscomb, J. AU - McCrory, D. C. CY - Rockville (MD) LA - eng N1 - Archibald, Nancy Lipscomb, Joseph McCrory, Douglas C Review Book NBK45258 [bookaccession] PB - Agency for Health Care Policy and Research (US) PY - 1999 ST - AHRQ Technical Reviews T2 - Resource Utilization and Costs of Care for Treatment of Chronic Headache TI - AHRQ Technical Reviews ID - 4191 ER - TY - JOUR AB - Background: Fatigue is common in patients with JIA and affects daily life negatively. We assessed the presence and severity of fatigue in patients with JIA, including factors presumed associated with fatigue (e.g., disease activity, disability, pain, physical activity, exercise capacity, and self-efficacy), and whether fatigue is related to participation in physical education classes, school attendance, and sports frequency. Methods: The current study used baseline data of 80 patients with JIA (age 8-13) who participated in an intervention aimed at promoting physical activity. Primary outcome measurements were fatigue, assessed using the Pediatric-Quality-of-Life-Inventory (PedsQl)-Fatigue-scale and energy level assessed using a VAS scale. Other outcome measurements were disease activity (VAS Physician Global Assessment Scale), disability (Childhood Health Assessment Questionnaire), physical activity (accelerometer), exercise capacity (Bruce treadmill test), self-efficacy (Childhood Arthritis Self-Efficacy Scale), and participation (self-report). Results: Sixty percent of patients with JIA suffered from daily low-energy levels; 27% suffered from very low-energy levels more than half the week. Low energy levels were best predicted by disability and low physical activity. Fatigue measured with the PEDsQL was higher compared to the control-population. Disability and low self-efficacy were main predictors of fatigue. Self-efficacy was a predictor of fatigue but did not act as moderator. Fatigue was a predictor for sports frequency but not for school attendance. Conclusion: Fatigue is a significant problem for JIA patients. Interventions aimed at reducing perceived disability, stimulating physical activity, and enhancing self-efficacy might reduce fatigue and thereby enhance participation. AN - WOS:000390277400001 AU - Armbrust, W. AU - Lelieveld, Ohtm AU - Tuinstra, J. AU - Wulffraat, N. M. AU - Bos, Gjfj AU - Cappon, J. AU - van Rossum, M. A. J. AU - Sauer, P. J. J. AU - Hagedoorn, M. C7 - 65 DA - Dec DO - 10.1186/s12969-016-0125-1 N1 - Armbrust, Wineke Lelieveld, Otto H. T. M. Tuinstra, Jolanda Wulffraat, Nico M. Bos, G. J. F. Joyce Cappon, Jeannette van Rossum, Marion A. J. Sauer, Pieter J. J. Hagedoorn, Mariet Wulffraat, Nico M/AAE-8929-2020; Hagedoorn, Mariet/B-5056-2010 Wulffraat, Nico M/0000-0001-9548-5562; Hagedoorn, Mariet/0000-0003-3444-3662 1546-0096 PY - 2016 ST - Fatigue in patients with Juvenile Idiopathic Arthritis: relationship to perceived health, physical health, self-efficacy, and participation T2 - Pediatric Rheumatology TI - Fatigue in patients with Juvenile Idiopathic Arthritis: relationship to perceived health, physical health, self-efficacy, and participation UR - ://WOS:000390277400001 VL - 14 ID - 2126 ER - TY - JOUR AB - Chronic pelvic pain (CPP) affects a significant number of women worldwide. Internationally, people with endometriosis report significant negative impact across many areas of their life. We aimed to use an online survey using the EndoCost tool to determine if there was any difference in the impact of CPP in those with vs. those without a confirmed diagnosis of endometriosis, and if there was any change in diagnostic delay since the introduction of clinical guidelines in 2005. 409 responses were received; 340 with a diagnosis of endometriosis and 69 with no diagnosis. People with CPP, regardless of diagnosis, reported moderate to severe dysmenorrhea and non-cyclical pelvic pain. Dyspareunia was also common. Significant negative impact was reported for social, academic, and sexual/romantic relationships in both cohorts. In the endometriosis cohort there was a mean diagnostic delay of eight years, however there was a reduction in both the diagnostic delay (p < 0.001) and number of doctors seen before diagnosis (p < 0.001) in those presenting more recently. Both endometriosis and CPP have significant negative impact. Whilst there is a decrease in the time to diagnosis, there is an urgent need for improved treatment options and support for women with the disease once the diagnosis is made. AD - NICM Health Research Institute, Western Sydney University, Penrith, NSW, 2751, Australia. m.armour@westernsydney.edu.au. Translational Health Research Institute, Western Sydney University, Penrith, NSW, 2751, Australia. m.armour@westernsydney.edu.au. NICM Health Research Institute, Western Sydney University, Penrith, NSW, 2751, Australia. School of Women's and Children's Health, University of New South Wales, Sydney, NSW, Australia. Department of Sociology/Anthropology, Middlebury College, Middlebury, VT, USA. Translational Health Research Institute, Western Sydney University, Penrith, NSW, 2751, Australia. AN - 33004965 AU - Armour, M. AU - Sinclair, J. AU - Ng, C. H. M. AU - Hyman, M. S. AU - Lawson, K. AU - Smith, C. A. AU - Abbott, J. C2 - PMC7529759 research grants and donations from foundations, universities, government agencies and industry. Sponsors and donors provide untied and tied funding for work to advance the vision and mission of the Institute. This study was not specifically supported by donor or sponsor funding to NICM. MA is a member of the clinical advisory board for Endometriosis Australia. JA: Medical Director, Endometriosis Australia (NFP). The other authors declare no competing interest. DA - Oct 1 DO - 10.1038/s41598-020-73389-2 DP - NLM ET - 2020/10/03 IS - 1 KW - Activities of Daily Living/psychology Adolescent Adult Australia Chronic Disease Delayed Diagnosis/*statistics & numerical data Endometriosis/*diagnosis/psychology Female Humans Middle Aged Pelvic Pain/*diagnosis/psychology *Quality of Life/psychology Surveys and Questionnaires Young Adult LA - eng N1 - 2045-2322 Armour, Mike Sinclair, Justin Ng, Cecilia H M Hyman, Mikayla S Lawson, Kenny Smith, Caroline A Abbott, Jason Journal Article Sci Rep. 2020 Oct 1;10(1):16253. doi: 10.1038/s41598-020-73389-2. PY - 2020 SN - 2045-2322 SP - 16253 ST - Endometriosis and chronic pelvic pain have similar impact on women, but time to diagnosis is decreasing: an Australian survey T2 - Sci Rep TI - Endometriosis and chronic pelvic pain have similar impact on women, but time to diagnosis is decreasing: an Australian survey VL - 10 ID - 3677 ER - TY - JOUR AB - Study Design: Retrospective case series. Purpose: The aim of the study is to report the clinical characteristics, early diagnosis, management, and outcome of children with multidrug-resistant (MDR) tubercular spondylodiscitis and to assess the early detection of rifampicin resistance using the Xpert MTB/RIF assay. Overview of Literature: MDR tuberculosis is on the rise, especially in developing countries. The incidence rate of MDR has been reported as 8.9% in children. Methods: A retrospective study of children aged <15 years of age who were diagnosed and treated for MDR tuberculosis of the spine was conducted. Confirmed cases of MDR tuberculosis and patients who had completed at least 18 months of second-line antituberculous treatment (ATT) were included. Children were treated with ATT for 24 months according to drug-susceptibility-test results. Outcome measures included both clinical and radiological measures. Clinical measures included pain, neurological status, and return to school. Radiological measures included kyphosis correction and healing status. Results: Six children with a mean age of 10 years were enrolled. The mean follow-up period was 12 months. All the children had previous history of treatment with first-line ATT, with an average of 13.6 months before presentation. Clinically, 50% (3/6 children) had psoas abscesses and 50% had spinal deformities. Radiologically, 50% (three of six children) had multicentric involvement. Three children underwent surgical decompression; two needed posterior stabilization with pedicle screws posteriorly followed by anterior column reconstruction. Early diagnosis of MDR was achieved in 83.3% (five of six children) with Xpert MTB/RIF assay. A total of 83.3% of the children were cured of the disease. Conclusions: Xpert MTB/RIF assay confers the advantage of early detection, with initiation of MDR drugs within an average of 10.5 days from presentation. The cost of second-line ATT drugs was 30 times higher than that of first-line ATT. AN - WOS:000457550900011 AU - Arockiaraj, J. AU - Robert, M. AU - Rose, W. AU - Amritanand, R. AU - David, K. S. AU - Krishnan, V. DA - Feb DO - 10.31616/asj.2017.0217 IS - 1 N1 - Arockiaraj, Justin Robert, Magdalenal Rose, Winsley Amritanand, Rohit David, Kenny Samuel Krishnan, Venkatesh 1976-7846 PY - 2019 SN - 1976-1902 SP - 77-85 ST - Early Detection and Analysis of Children with Multidrug-Resistant Tuberculosis of the Spine T2 - Asian Spine Journal TI - Early Detection and Analysis of Children with Multidrug-Resistant Tuberculosis of the Spine UR - ://WOS:000457550900011 VL - 13 ID - 1953 ER - TY - JOUR AB - OBJECTIVE: This study reports the pain sensitivity of children with headache and their family members, as well as the prevalence of recurring aches, psychosocial life, and family environment of children with headache at preschool age. DESIGN: A representative population-based sample of 1443 families expecting their first child were followed over 7 years. A screening questionnaire relating to the child's headache was sent to parents of a representative sample of 1132 6-year-old children. Of 144 children suffering from headache, 106 (76%) were examined and interviewed clinically. Ninety-six children with primary headache (58 migraine and 38 tension-type headache children) and matched controls (n = 96) were included in further examinations. RESULTS: Children with headache were more often extremely sensitive to pain according to their parents, were more excited about physical examinations, cried more often during blood sampling or vaccination, avoided play or games more often because they were afraid of hurting themselves, and had recurring abdominal and growing pains more often than did control children. The fathers of children with headache were more often extremely sensitive to pain. Children with headache reacted with somatic symptoms, usually with pain and functional intestinal disorders in stress situations, felt more tired, and had more ideations of death during the previous month. They had also had more problems in day care and fewer hobbies such as scout or club meetings than did control children. More mothers of tension-type headache children than those of migraine children reported that they were considerably sensitive to pain. Tension-type headache children also had a poorer family environment; the family atmosphere was more often unhappy and the relationship between the parents was more often distant than in the families of children with migraines. CONCLUSIONS: In addition to somatic factors, it is important to consider the child's pain sensitivity, reaction to various stress situations, and family functioning when studying childhood headache. The child's coping mechanisms can be supported by information given by the parents. School entry can be considered a suitable period for careful investigation into possible occurrence of headache and also for giving information about headache and its management. AD - Department of Child Neurology, University of Turku, Finland. minna.aromaa@tyks.fi AN - 10920150 AU - Aromaa, M. AU - Sillanpää, M. AU - Rautava, P. AU - Helenius, H. DA - Aug DO - 10.1542/peds.106.2.270 DP - NLM ET - 2000/08/02 IS - 2 Pt 1 KW - Child Child, Preschool Chronic Disease Family/*psychology Finland Follow-Up Studies Headache/*psychology Humans Migraine Disorders/psychology Pain Measurement *Pain Threshold Parent-Child Relations Social Adjustment Social Environment Somatoform Disorders/psychology Tension-Type Headache/psychology LA - eng N1 - Aromaa, M Sillanpää, M Rautava, P Helenius, H Journal Article Research Support, Non-U.S. Gov't United States Pediatrics. 2000 Aug;106(2 Pt 1):270-5. doi: 10.1542/peds.106.2.270. PY - 2000 SN - 0031-4005 (Print) 0031-4005 SP - 270-5 ST - Pain experience of children with headache and their families: A controlled study T2 - Pediatrics TI - Pain experience of children with headache and their families: A controlled study VL - 106 ID - 3208 ER - TY - JOUR AB - OBJECTIVE: Our objective was to study the prevalence of different headache types, characterizations, and triggers of headache in Finnish children starting school. METHODS: Questionnaires were sent to 1,132 families with 6-year-old children. Children with headache disturbing their daily activities (n=96) and an asymptomatic control group of children (n=96) participated in a clinical interview and examination. RESULTS: Children with headache had significantly more bruxism (odds ratio [OR], 1.9; 95% CI, 1.0 to 3.4), tenderness in the occipital muscle insertion areas (OR, 4.8; 95% CI, 1.8 to 12.7), and tenderness in the temporomandibular joint areas (OR, 2.8; 95% CI, 1.3 to 6.0). They also had more travel sickness (OR, 3.4; 95% CI, 1.7 to 6.7) than control children. Eating ice cream (OR, 5.3; 95% CI, 1.4 to 20.3), fear (OR, 3.7; 95% CI, 1.2 to 11.2), and anxiety (OR, 3.2; 95% CI, 1.0 to 10.8) triggered headache more often in migraineurs than in children with tension-type headache. Children with migraine also reported more frequently abdominal (OR, 5.6; 95% CI, 1.7 to 18.1) and other (OR, 3.5; 95% CI, 1.2 to 9.8) pain concurrently with headache, and they used medication for pain relief more often (OR, 3.1; 95% CI, 1.0 to 9.5). CONCLUSIONS: Headache classification in children may be improved by palpation of occipital muscle insertions and temporomandibular joint areas, and by discerning a history of triggering events and concurrent symptoms. AD - Department of Child Neurology, University of Turku, Finland. AN - 9633718 AU - Aromaa, M. AU - Sillanpää, M. L. AU - Rautava, P. AU - Helenius, H. DA - Jun DO - 10.1212/wnl.50.6.1729 DP - NLM ET - 1998/06/20 IS - 6 KW - Bruxism/complications/epidemiology Child Facial Muscles/physiopathology Female Headache/complications/*epidemiology/therapy Humans Male Migraine Disorders/physiopathology Motion Sickness/complications/epidemiology Pain/complications/epidemiology Prevalence Reference Values *Students Surveys and Questionnaires Temporomandibular Joint/physiopathology Tension-Type Headache/etiology/physiopathology LA - eng N1 - Aromaa, M Sillanpää, M L Rautava, P Helenius, H Journal Article Research Support, Non-U.S. Gov't United States Neurology. 1998 Jun;50(6):1729-36. doi: 10.1212/wnl.50.6.1729. PY - 1998 SN - 0028-3878 (Print) 0028-3878 SP - 1729-36 ST - Childhood headache at school entry: a controlled clinical study T2 - Neurology TI - Childhood headache at school entry: a controlled clinical study VL - 50 ID - 3521 ER - TY - JOUR AB - Increased prescribing of opioids has been associated with an epidemic of nonmedical prescription opioid use in the United States; adolescents and young adults are particularly vulnerable to opioid misuse. The role of physicians as health care providers, educators, and confidants for their adolescent patients equips them to intervene in adolescent opioid misuse. The authors advocate for improving the education of physicians and residents regarding opioid use and misuse among adolescents. To achieve this, we can require residency education that includes opioid misuse and appropriate prescribing, widely disseminate existing resources on management of pain and opioid misuse, and develop pain management and addiction mentorship programs. AN - WOS:000452676700004 AU - Arora, N. S. AU - Marcotte, K. M. AU - Hopper, J. A. DO - 10.1080/08897077.2017.1356788 IS - 1 N1 - Arora, Nonie S. Marcotte, Kayla M. Hopper, John A. Hopper, John/AAJ-5878-2021 Hopper, John/0000-0003-2445-8043; Arora, Nonie/0000-0001-8399-3818 1547-0164 PY - 2018 SN - 0889-7077 SP - 6-8 ST - Reducing opioid misuse among adolescents through physician education T2 - Substance Abuse TI - Reducing opioid misuse among adolescents through physician education UR - ://WOS:000452676700004 VL - 39 ID - 2043 ER - TY - JOUR AB - Background A scarcity of studies on the role of resilience resources (RRs) and vulnerability risk (VR) in children and adolescents with primary headache hampers the development of a risk-resilience model for pediatric headaches. Objective To examine the extent to which headache frequency and diagnosis are associated with RRs and VR and explore possible predictors of low RRs and high VR in a cross-sectional population-based study in adolescents. Methods This is a cross-sectional population study conducted in a small city in Brazil (Delfinopolis). Consents and analyzable data were obtained from 339/378 adolescents (89.7%). RRs and VR were assessed using the validated Brazilian version of the Resiliency Scales for Children and Adolescents, completed by the adolescents. Parents filled a structured questionnaire assessing sociodemographic and headache characteristics, as well as the Brazilian-validated version of the Strengths and Difficulties Questionnaire added to the impact supplement to evaluate the adolescent's psychosocial adjustment skills. Teachers completed a structured questionnaire about the students' school performance. Results A higher frequency of headache was associated with lower RRs (F-3,F-335 = 2.99, p = 0.031) and higher VR (F-3,F-335 = 4.05, p = 0.007). Headache diagnosis did not significantly influence the risk of having lower RRs or higher VR. In the exploratory analyses, females (OR 3.07; 95% CI: 1.16-9.3) and individuals with psychosocial adjustment problems (OR 7.5; 95% CI: 2.51-22.4) were predictors of low RRs, and prenatal exposure to tobacco (OR 5.6; 95% CI: 1.57-20.9) was a predictor of high VR in adolescents with primary headache. Conclusions The risk of low RRs and high VR was associated with a higher headache frequency, but not with headache diagnosis. These findings may contribute to the development of a risk-resilience model of headaches in the pediatric population and help identify novel targets and develop effective resources for successful interventions. AN - WOS:000628878000001 AU - Arruda, M. A. AU - Arruda, R. AU - Landeira-Fernandez, J. AU - Anunciacao, L. AU - Bigal, M. E. DA - Mar DO - 10.1111/head.14078 IS - 3 N1 - Arruda, Marco Antonio Arruda, Renato Landeira-Fernandez, J. Anunciacao, Luis Bigal, Marcelo Eduardo 1526-4610 PY - 2021 SN - 0017-8748 SP - 546-557 ST - Resilience and vulnerability in adolescents with primary headaches: A cross-sectional population-based study T2 - Headache TI - Resilience and vulnerability in adolescents with primary headaches: A cross-sectional population-based study UR - ://WOS:000628878000001 VL - 61 ID - 1749 ER - TY - JOUR AB - BACKGROUND: Nerve root decompression with instrumented spondylodesis is the most frequently performed surgical procedure in the treatment of patients with symptomatic low-grade spondylolytic spondylolisthesis. Nerve root decompression without instrumented fusion, i.e. Gill's procedure, is an alternative and less invasive approach. A comparative cost-effectiveness study has not been performed yet. We present the design of a randomised controlled trial on cost-effectiveness of decompression according to Gill versus instrumented spondylodesis. METHODS/DESIGN: All patients (age between 18 and 70 years) with sciatica or neurogenic claudication lasting more than 3 months due to spondylolytic spondylolisthesis grade I or II, are eligible for inclusion. Patients will be randomly allocated to nerve root decompression according to Gill, either unilateral or bilateral, or pedicle screw fixation with interbody fusion. The main primary outcome measure is the functional assessment of the patient measured with the Roland Disability Questionnaire for Sciatica at 12 weeks and 2 years. Other primary outcome measures are perceived recovery and intensity of leg pain and low back pain. The secondary outcome measures include, incidence of re-operations, complications, serum creatine phosphokinase, quality of life, medical consumption, costs, absenteeism, work perception, depression and anxiety, and treatment preference. The study is a randomised prospective multicenter trial in which two surgical techniques are compared in a parallel group design. Patients and research nurse will not be blinded during the follow-up period of 2 years. DISCUSSION: Currently, nerve root decompression with instrumented fusion is the golden standard in the surgical treatment of low-grade spondylolytic spondylolisthesis, although scientific proof justifying instrumented spondylodesis over simple decompression is lacking. This trial is designed to elucidate the controversy in best surgical treatment of symptomatic patients with low-grade spondylolytic spondylolisthesis. AD - Department of Neurosurgery, Leiden University Medical Center, Leiden, The Netherlands. m.arts@mchaaglanden.nl AN - 18822175 AU - Arts, M. P. AU - Verstegen, M. J. AU - Brand, R. AU - Koes, B. W. AU - van den Akker, M. E. AU - Peul, W. C. C2 - PMC2570682 DA - Sep 28 DO - 10.1186/1471-2474-9-128 DP - NLM ET - 2008/09/30 KW - Adolescent Adult Aged Bone Screws Cost-Benefit Analysis Creatine Kinase/blood Decompression, Surgical/adverse effects/*economics/methods Depression Female Health Care Costs Humans Male Middle Aged Outcome Assessment, Health Care Patient Satisfaction Prospective Studies Quality of Life Sciatica/economics/*etiology/*surgery Spinal Fusion/adverse effects/*economics/methods Spondylolisthesis/*complications Young Adult LA - eng N1 - 1471-2474 Arts, Mark P Verstegen, Marco J T Brand, Ronald Koes, Bart W van den Akker, M Elske Peul, Wilco C Journal Article Multicenter Study Randomized Controlled Trial Research Support, Non-U.S. Gov't BMC Musculoskelet Disord. 2008 Sep 28;9:128. doi: 10.1186/1471-2474-9-128. PY - 2008 SN - 1471-2474 SP - 128 ST - Cost-effectiveness of decompression according to Gill versus instrumented spondylodesis in the treatment of sciatica due to low grade spondylolytic spondylolisthesis: a prospective randomised controlled trial [NTR1300] T2 - BMC Musculoskelet Disord TI - Cost-effectiveness of decompression according to Gill versus instrumented spondylodesis in the treatment of sciatica due to low grade spondylolytic spondylolisthesis: a prospective randomised controlled trial [NTR1300] VL - 9 ID - 3778 ER - TY - JOUR AB - Next to headache recurrent gastro-intestinal complaints constitute the most common reason for medical consultation among daycare and school children. The use of more sophisticated examination methods has shown that in up to 50 per cent of cases the cause of the gastric complaints is a treatable disease or a functional anomaly of the gastro-intestinal tract. The commonest conditions are lactose intolerance, gluten sensitivity, gastro-oesophageal reflux, and gastritis. In some cases stomach pain is triggered by psychosomatic mechanisms. Depending upon the child's age, aetiological indications can sometimes be derived from history taking. In many cases the investigations can be made in the out-patient clinic. The cornerstones of treatment are various kinds of dietary elimination regimens, prokinetic agents, and antibiotics. Recently, the investigation of neuroendocrinological and neurophysiological processes related to psychosomatic causes of gastric complaints has once again become common. AD - Kliniken för barnsjukdomar, Tammerfors universitetssjukhus, Tammerfors universitet. AN - 9497614 AU - Ashorn, M. DA - Feb DP - NLM ET - 1998/03/14 IS - 2 KW - Abdominal Pain/*etiology/physiopathology/psychology Child Child, Preschool Diet Female Gastrointestinal Diseases/diagnosis/*physiopathology Humans Male Psychophysiologic Disorders/diagnosis/psychology Recurrence Stomach Diseases/diagnosis/*physiopathology/psychology LA - swe N1 - Ashorn, M English Abstract Journal Article Sweden Nord Med. 1998 Feb;113(2):43-5, 59. OP - Recidiverande magbesvär hos barn. PY - 1998 SN - 0029-1420 (Print) 0029-1420 SP - 43-5, 59 ST - [Recurrent stomach complaints in children] T2 - Nord Med TI - [Recurrent stomach complaints in children] VL - 113 ID - 3517 ER - TY - JOUR AB - OBJECTIVE: Inflammatory bowel disease (IBD) and functional abdominal pain (FAP) are associated with debilitating symptoms and frequent medical visits that may disrupt school functioning. The aim of this study was to assess school-related quality of life and school absenteeism in children with IBD, compared with FAP and healthy controls. METHODS: School absenteeism and participation in school and after-school activities data were obtained for 43 children with Crohn disease (CD), 31 children with ulcerative colitis (UC), 42 children with FAP, and 30 age-matched healthy controls for the 2013-2014 school year. We used a semistructured questionnaire for both children and parents. For diminishing recall bias, absenteeism data were cross-matched with the patient's school annual report cards. RESULTS: Children with FAP, CD, and UC missed significantly more school days than age-matched healthy controls (17.6 [8.75-30], 24 [14-30], and 21 [12-25] vs 5.1 [3.75-6.25], respectively, P < 0.001). Compared with children with FAP, absenteeism because of medical appointments and hospitalization was significantly greater in children with CD and UC (8.8 [4-14] and 7.1 [3-10] vs 4.4 [2-6.25], P = 0.001). Participation of children with FAP and IBD in various school and after-school activities was significantly reduced compared with healthy controls. There was no difference in school attendance and functioning between children with IBD and FAP. CONCLUSIONS: FAP has a significant impact on school attendance and functioning similar to IBD. These findings show that significant psychosocial and academic difficulties are faced not only by children with chronic diseases like IBD but also by children with FAP. AU - Assa, Amit AU - Ish-Tov, Alona AU - Rinawi, Firas AU - Shamir, Raanan DA - 2015/11// DO - 10.1097/MPG.0000000000000850 DP - PubMed IS - 5 J2 - J Pediatr Gastroenterol Nutr KW - Abdominal Pain Absenteeism Adolescent Child Chronic Disease Colitis, Ulcerative Crohn Disease Female Humans Male Parents Quality of Life Schools Surveys and Questionnaires LA - eng PY - 2015 SN - 1536-4801 SP - 553-557 ST - School Attendance in Children With Functional Abdominal Pain and Inflammatory Bowel Diseases T2 - Journal of Pediatric Gastroenterology and Nutrition TI - School Attendance in Children With Functional Abdominal Pain and Inflammatory Bowel Diseases UR - http://www.ncbi.nlm.nih.gov/pubmed/25950089 VL - 61 ID - 83 ER - TY - JOUR AB - Objective: To identify differences in repositioning error in adolescents with and without non-specific chronic low back pain (NSCLBP), sub-groups of NSCLBP and in different spinal regions. Methods: Spinal repositioning error was measured during a seated task. Variables were constant error (CE), absolute error (AE) and variable error (VE) for lower lumbar, upper lumbar and lumbar angles. 28 subjects with NSCLBP were sub-classified using O'Sullivans system and compared to 28 healthy controls. Results: Significant differences were noted for AE between adolescents with and without NSCLBP, but no differences were found for CE or VE. When sub-grouped there was a pattern for lower AE and higher VE in the flexion sub-group. This group also displayed a tendency to undershoot the criterion position in the lower lumbar spine. Greater VE was noted in the extension sub-group and those with no NSCLBP in the upper lumbar compared to the lower lumbar spine. Conclusions: Differences in spinal repositioning errors were noted between adolescents with and without NSCLBP and sub-groups of NSCLBP. Those with flexion-pattern NSCLBP had the lowest levels of spinal repositioning ability. Individuals with no-LBP (low-back pain) or extension-pattern NSCLBP displayed greater variability in the upper lumbar spine. (C) 2013 Elsevier Ltd. All rights reserved. AN - WOS:000324341300010 AU - Astfalck, R. G. AU - O'Sullivan, P. B. AU - Smith, A. J. AU - Straker, L. M. AU - Burnett, A. F. DA - Oct DO - 10.1016/j.math.2013.02.005 IS - 5 N1 - Astfalck, Roslyn G. O'Sullivan, Peter B. Smith, Anne J. Straker, Leon M. Burnett, Angus F. Study, Raine/K-4517-2013; Study, Raine/G-9547-2015; /B-2407-2013 /0000-0002-7786-4128; O'Sullivan, Peter/0000-0002-3982-4088 PY - 2013 SN - 1356-689X SP - 410-417 ST - Lumbar spine repositioning sense in adolescents with and without non-specific chronic low back pain - An analysis based on sub-classification and spinal regions T2 - Manual Therapy TI - Lumbar spine repositioning sense in adolescents with and without non-specific chronic low back pain - An analysis based on sub-classification and spinal regions UR - ://WOS:000324341300010 VL - 18 ID - 2347 ER - TY - JOUR AB - BACKGROUND: Regular physical activity (PA) of moderate intensity, has significant benefits for health. To our knowledge, no previous studies have examined the prevalence of low back pain (LBP) in a Bosnia and Herzegovina. The goal of this study is to present the data on prevalence of low back pain (LBP) in young adults and its association with PAPA. METHODS: Six months prevalence were assessed using questionnaire for grading pain, and graded back pain was determined using the Chronic Pain Scale (CPS). The CPS is a multidimensional measure that assesses 2 dimensions of overall chronic pain severity: pain intensity and pain-related disability. The study sample presented (N.=330) female students and (N.=213) male students. RESULTLTS: 78.5% of all students suffered pains at some point over the past six months. Female students reported higher prevalence of LBP 82.4%, compared to the male students 72.3%. The average value of pain intesity in the past 6 months in women is 2.80 and 2.31 in men on a numerical scale from 0 to 10. Females had higher intensity and disability scores. CONCLUSIONS: The key importance is the fact that the population of students needs to be offered such PAPA that will not include vigorous activities. AN - WOS:000400412600001 AU - Atikovic, A. AU - Pavletic, M. S. AU - Kalinski, S. D. AU - Bilalic, J. AU - Kurt, A. DA - May DO - 10.23736/s0393-3660.16.03371-4 IS - 5 N1 - Atikovic, Almir Pavletic, Mitija S. Kalinski, Suncica D. Bilalic, Jasmin Kurt, Almir Kalinski, Suncica D/H-2808-2015; Kalinski, Suncica Delas/AAN-2806-2021; Atikovic, Almir/AAK-9816-2020 Kalinski, Suncica D/0000-0002-0833-6719; Atikovic, Almir/0000-0002-3395-5044 1827-1812 PY - 2017 SN - 0393-3660 SP - 229-236 ST - Prevalence and risk factors of low back pain among undergraduate students in Bosnia and Herzegovina T2 - Gazzetta Medica Italiana Archivio Per Le Scienze Mediche TI - Prevalence and risk factors of low back pain among undergraduate students in Bosnia and Herzegovina UR - ://WOS:000400412600001 VL - 176 ID - 2099 ER - TY - JOUR AB - Background: Refractive errors are common eye disorders and are leading causes of visual impairment in the general population. Children with uncorrected refractive error may experience reduced visual acuity, transient blurring, headache and persistent ocular discomforts particularly for close work which can impair reading efficiency and school performance. Aim: This article documents the prevalence of refractive errors in school-age children of different ethnic origins. The goal is to identify possible variation in measuring techniques and diagnostic criteria, as well as limitations of studies, to provide a clear direction for future studies. Methods: The review was undertaken through a detailed evaluation of peer-reviewed publications of primary research on this topic. The keywords for the search included 'refractive error', 'hyperopia', 'myopia', 'astigmatism' and 'school children'. Only epidemiological studies with participants between 5 and 18 years of age were included. Results: Although several population and school-based studies have been conducted in various racial groups and populations, their findings were diverse owing to inconsistencies in the methods applied in identifying children in need of refraction, measurement techniques and diagnostic criteria for refractive errors. There are also some limitations associated with the sampling design and characteristics, which may have influenced the outcome measures. Conclusion: Despite the problems inherent in the studies, the review indicates that refractive error in school-age children is a public health concern in those populations and warrants additional research that will provide reliable data for proper planning of intervention strategies. AN - WOS:000468533000001 AU - Atowa, U. C. AU - Hansraj, R. AU - Wajuihian, S. O. C7 - a461 DA - May DO - 10.4102/aveh.v78i1.461 IS - 1 N1 - Atowa, Uchenna C. Hansraj, Rekha Wajuihian, Samuel O. Hansraj, Rekha/U-7747-2019 Atowa, Uchenna Chigozirim/0000-0002-5188-2678; WAJUIHIAN, SAM/0000-0002-6875-8788; Hansraj, Rekha/0000-0003-1487-6380 2410-3039 PY - 2019 SN - 0378-9411 ST - Vision problems: A review of prevalence studies on refractive errors in school-age children T2 - African Vision and Eye Health Journal TI - Vision problems: A review of prevalence studies on refractive errors in school-age children UR - ://WOS:000468533000001 VL - 78 ID - 1921 ER - TY - JOUR AB - The purpose of this study was to investigate the effectiveness of Acceptance and Commitment Therapy (ACT) based psycho-educational group on test anxiety of high school students. The participants were six senior high school students with high level of test anxiety and all of the participants were female. They were selected by multi-stage sampling method. Psycho-educational group was designed to include six processes of psychological flexibility/inflexibility, that is the core concept of ACT; and it lasted six weeks by 90 minutes per week. Participants were interviewed before and after the psychoeducation group. The content analysis was applied and the findings of ACT-based psychoeducation program revealed that participants' test anxiety and psychological inflexibility level as well as how they handle the problem have changed as a result of this psycho-educational group process. The participants also stated that their definition of test anxiety problem have changed after the group process. Implications and suggestions for future research and practice were discussed. AN - WOS:000565232500009 AU - Aydin, Y. AU - Aydin, G. DA - Sep DO - 10.9779/pauefd.584565 IS - 50 N1 - Aydin, Yasin Aydin, Gokcen Aydin, Gokcen/AAA-2394-2021 1309-0275 PY - 2020 SN - 1301-0085 SP - 180-200 ST - Acceptance and Commitment Therapy Based Psychoeducation Group for Test Anxiety: A Case Study of Senior High School Students T2 - Pamukkale Universitesi Egitim Fakultesi Dergisi-Pamukkale University Journal of Education TI - Acceptance and Commitment Therapy Based Psychoeducation Group for Test Anxiety: A Case Study of Senior High School Students UR - ://WOS:000565232500009 ID - 1801 ER - TY - JOUR AB - Abdominal pain is a common reason for medical visits. We examined the prevalence, gastrointestinal, and emotional significance of abdominal pain in a population-based cohort serially followed up from birth to 17 years. Children and adolescents from Generation 2 of the Raine Study participated in comprehensive cross-sectional assessments at ages 2, 5, 8, 10, 14 and 17 years. At 17 years, medical history, general health, gastrointestinal symptoms, medications, health practitioner attendance, and self-rated unhappiness were recorded. Longitudinal data regarding abdominal pain or unhappiness, from serial questionnaires, were analysed to identify factors associated with abdominal pain and adverse emotional health at age 17 years. Females experienced more abdominal pain than males at all ages (p < 0.05). Seventeen-year-old adolescents with abdominal pain reported a higher prevalence of depression, anxiety, being bullied at school, and poorer health status than those without abdominal pain (p < 0.05 for all). Abdominal pain and unhappiness during childhood and mid-adolescence were prospectively associated with recurrent abdominal pain, anxiety, depression and unhappiness during late adolescence (p < 0.05 for all). In conclusion, abdominal pain in children and adolescents associates with depression, anxiety, being bullied, unhappiness and reduced overall health-rating during adolescence. Awareness of these factors may guide management decisions. AN - WOS:000562806900007 AU - Ayonrinde, O. T. AU - Ayonrinde, O. A. AU - Adams, L. A. AU - Sanfilippo, F. M. AU - O'Sullivan, T. A. AU - Robinson, M. AU - Oddy, W. H. AU - Olynyk, J. K. C7 - 1646 DA - Feb DO - 10.1038/s41598-020-58543-0 IS - 1 N1 - Ayonrinde, Oyekoya T. Ayonrinde, Oyedeji A. Adams, Leon A. Sanfilippo, Frank M. O'Sullivan, Therese A. Robinson, Monique Oddy, Wendy H. Olynyk, John K. Ayonrinde, Oyekoya/K-2337-2019; Sanfilippo, Frank/H-9334-2013 Ayonrinde, Oyekoya/0000-0002-0598-151X; Olynyk, John/0000-0003-0417-3411; Ayonrinde, Oyedeji/0000-0002-8799-4225; Robinson, Monique/0000-0001-8834-6089; Sanfilippo, Frank/0000-0003-3639-0787 PY - 2020 SN - 2045-2322 ST - The relationship between abdominal pain and emotional wellbeing in children and adolescents in the Raine Study T2 - Scientific Reports TI - The relationship between abdominal pain and emotional wellbeing in children and adolescents in the Raine Study UR - ://WOS:000562806900007 VL - 10 ID - 1840 ER - TY - JOUR AB - Fourteen patients or their immediate family were interviewed about their experiences of having either unilateral or bilateral external distraction osteogenesis of the mandible. The patients showed a high level of co-operation with treatment. Six of the 14 patients required repeat distractions, and had been informed and accepted that this was a possibility before the initial distraction. However, patients or their parents expressed some reservations about the extraoral distractors, which prevented them from practising their favourite sport and made them vulnerable to bullying by their friends and colleagues. Patients had moderate pain when the appliances were removed. They all expressed their satisfaction with the results and would recommend this treatment to others. Problems, including speech, eating, pain, and sleeping difficulties, were encountered by patients at all stages of treatment. Of considerable concern was the disruption of education when the child was treated during the school term. (C) 2002 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Science Ltd. All rights reserved. AN - WOS:000179138700006 AU - Ayoub, A. F. AU - Duncan, C. M. AU - McLean, G. R. AU - Moos, K. F. AU - Chibbaro, P. D. DA - Oct DO - 10.1016/s0266-4356(02)00191-2 IS - 5 N1 - Ayoub, AF Duncan, CM McLean, GR Moos, KF Chibbaro, PD Ayoub, Ashraf/0000-0002-2760-6008 1532-1940 PY - 2002 SN - 0266-4356 SP - 397-405 ST - Response of patients and families to lengthening of the facial bones by extraoral distraction osteogenesis: a review of 14 patients T2 - British Journal of Oral & Maxillofacial Surgery TI - Response of patients and families to lengthening of the facial bones by extraoral distraction osteogenesis: a review of 14 patients UR - ://WOS:000179138700006 VL - 40 ID - 2820 ER - TY - JOUR AB - The frequency and significance of headache in children and adolescent has been drawing more attention nowadays. Similarly, growing body of data is being collected on the quality of life of headache in children and adolescent to which increased attention is paid. Compared with other chronic disorders, headache in children has more negative effect on school performance, as well as emotional status. As for school children, it is reported that these children could not go to school on a regular basis, they do less performance and their careers are negatively affected on the long-term. Accompanying symptoms such as depression, somatization, anxiety also impairs the quality of life. Early identification and treatment of headache will not only improve a health condition, but also will provide advancement in academic and social area as well as psychological development for children with headache. AN - WOS:000389744200021 AU - Ayta, S. AU - Uluduz, D. AU - Poyraz Findik, O. T. AU - Ozge, A. IS - 1 N1 - Ayta, Semih Uluduz, Derya Poyraz Findik, Onur Tugce Ozge, Aynur Findik, Onur Tugce Poyraz/Y-4044-2018 Findik, Onur Tugce Poyraz/0000-0002-2376-7592 PY - 2016 SN - 1302-1664 SP - 185-193 ST - Quality of Life in Children and Adolescents With Primary Headache Disorders T2 - Journal of Neurological Sciences-Turkish TI - Quality of Life in Children and Adolescents With Primary Headache Disorders UR - ://WOS:000389744200021 VL - 33 ID - 2191 ER - TY - JOUR AB - Objective: We aimed to detailly investigate the effects of in school, after school academic activities and hobbies on the frequencies and properties of headache, in high academic expectation school group. Methods: The study was carried out among the all students in a high school in Mersin, Turkey. They were all given a standard questionnaire that consisted of the questions regarding the demographics, presence or absence of headache, if yes detailed characteristics questioned, the after school activities, percentage of their happiness and an international scale for the establishment of daily life routines, the MIDAS. esults: 611 subjects (70.4 % of the total population) were selected to be enrolled for evaluation. The groups were even and were well capable of representing the community. 134 (21.9%) had no headache at all. 278 subjects (45.5%) had TTH and 175 (28.6%) of the participants had migraine. The MIDAS scores were highest in the group who had migraine with aura (p<0.001). The proposed cut-off values of study/hobbies time in a week are calculated to be 5.54 +/- 0.32 hours for headache disorders (in general), 6.12 +/- 0.57 hours for migraine and 5.23 +/- 0.39 hours for TTH. Conclusion: This study demonstrates that headache is a commonly encountered problem among the young adults that raises problems both in their academic and social lives. If this problem is kept unresolved, these young adults that represent the highest academic group among the com-munity carry the risk forming an unhealthy society in terms of both academic and social life in the future. AN - WOS:000300363200003 AU - Aytacoglu, H. AU - Ozge, A. AU - Kostekci, I. AU - Tasdelen, B. AU - Oksuz, N. AU - Toros, F. IS - 4 N1 - Aytacoglu, Hakan Ozge, Aynur Kostekci, Ilknur Tasdelen, Bahar Oksuz, Nevra Toros, Fevziye Oksuz, Nevra/AAH-7476-2019; Tasdelen, Bahar/G-4291-2015 Tasdelen, Bahar/0000-0001-8146-4912 PY - 2011 SN - 1302-1664 SP - 453-464 ST - The Effects of Daily Variables on Primary Headache Disorders in High-School Children; A Proposal For A Cut-off Value For Study/Leisure Time Regarding Headache Types T2 - Journal of Neurological Sciences-Turkish TI - The Effects of Daily Variables on Primary Headache Disorders in High-School Children; A Proposal For A Cut-off Value For Study/Leisure Time Regarding Headache Types UR - ://WOS:000300363200003 VL - 28 ID - 2520 ER - TY - JOUR AB - Background: Cancer affects not only the patient but also their entire family, especially adolescents. Adolescents whose parents are ill may manifest their distress through changes in school performance, physical complaints of pain and discomfort, as well as changes in social and interpersonal relations. There has been very little research about the effects of cancer on adolescents in Iran. Objectives:The purpose of this qualitative study was to explore the Iranian adolescents' experiences when living with a parent with cancer. Patients and Methods: In this research, the descriptive-explorative approach was used. There were a total of 27 participants. Purposeful sampling was used and data collection methods were semi-structured deep interviews. Constant comparative analysis was used to study the data. Results: The findings of this study showed that the main experiences of these adolescents were categorized into seven themes: 1 psychological problems of adolescents; 2-supportive-educative needs; 3- cancer as a two edged sword in family relationships; 4- stages of confrontation with the parent's cancer; 5- effect of cancer on social dimensions; 6- affective and helpful supportive agents; 7- Need of support for education under special conditions. Conclusions: This research showed that Iranian adolescents had the same experiences as other adolescents in other countries in many aspects yet in some issues, such as religious strategy they had strong religious beliefs that would help them cope with their parents' cancer. Also it was shown that we must plan a program in which education and support should be provided to enable adolescents to cope with this detrimental situation with minimal disruption. AN - WOS:000375221700014 AU - Azarbarzin, M. AU - Malekian, A. AU - Taleghani, F. C7 - e26410 DA - Jan DO - 10.5812/ircmj.26410 IS - 1 N1 - Azarbarzin, Mehrdad Malekian, Azadeh Taleghani, Fariba Azarbarzin, Mehrdad/Q-5887-2017 Azarbarzin, Mehrdad/0000-0002-8824-8515 2074-1812 PY - 2016 SN - 2074-1804 ST - Adolescents' Experiences When Living With a Parent With Cancer: A Qualitative Study T2 - Iranian Red Crescent Medical Journal TI - Adolescents' Experiences When Living With a Parent With Cancer: A Qualitative Study UR - ://WOS:000375221700014 VL - 18 ID - 2199 ER - TY - JOUR AB - Study Objective: The study sought to gain an in-depth understanding of primary dysmenorrhea management and coping strategies for dysmenorrhea among adolescents and young adults who were in school. Design: The study adopted a qualitative exploratory approach using a descriptive phenomenology to explore the phenomenon of interest. Setting: The study was conducted in two educational institutions in Accra, Ghana: a Senior High School (SHS) and a University. Participants and Data Collection: Sixteen participants were purposively recruited (8 SHS and 8 University students) through snowball sampling. Individual interviews were conducted in English, audio-taped, transcribed and analysed using content analysis procedures. Informed consent was obtained from all participants and rigor was ensured through prolonged engagement and member checking. Results: Participants employed both pharmacologic (orthodox and herbal) and nonpharmacologic approaches such as warm compress, exercise, and water and diet therapy for their dysmenorrhea. Students' dysmenorrhea was managed at the school clinic and the hospital. Health professionals demonstrated negative attitudes towards dysmenorrhea management. Students coped with dysmenorrhea by planning activities before the onset of pain, receiving social and spiritual support, and developing a mind-set to bear pain. Conclusions: Individualized approaches should be employed to enhance dysmenorrhea management. Health professionals should be educated on dysmenorrhea to improve their attitude and skills for dysmenorrhea management. AN - WOS:000356119500009 AU - Aziato, L. AU - Dedey, F. AU - Clegg-Lamptey, J. N. A. DA - Jun DO - 10.1016/j.jpag.2014.07.002 IS - 3 N1 - Aziato, Lydia Dedey, Florence Clegg-Lamptey, Joe Nat A. 1873-4332 PY - 2015 SN - 1083-3188 SP - 163-169 ST - Dysmenorrhea Management and Coping among Students in Ghana: A Qualitative Exploration T2 - Journal of Pediatric and Adolescent Gynecology TI - Dysmenorrhea Management and Coping among Students in Ghana: A Qualitative Exploration UR - ://WOS:000356119500009 VL - 28 ID - 2235 ER - TY - JOUR AB - BACKGROUND: Treatment procedures are the most common sources of pain in children. Children with chronic diseases such as thalassemia experience many pains during painful procedures including at times of diagnosis, treatment and control of their disease. Several methods have been reported to reduce pain. Clinical professionals usually use distraction techniques to reduce pain. However, there is no agreement between them that which distraction technique is better for reducing pain. The aim of this study was omparing the effects of regular breathing exercise and making bubbles on the pain of catheter insertion in school age children. METHODS: This was a clinical trial on 60 children in the age range of 6 to 12 years, who were suffering from thalassemia and had a file in the Center for Thalassemia. Participants were randomly divided into two groups of experiment and control. Bubble making was performed for the first group and regular breathing exercise was performed for the second group. Data were collected using a demographic questionnaire, a scale for pediatric pain behavioral symptoms and Numeric Pain Rating Scale. Data were analyzed using descriptive (frequency, mean and standard deviation) and inferential statistics (ANOVA, Kruskal Wallis, and Mann Whitney U tests and Spearman correlation). RESULTS: The mean pain score based on the numerical scale was 5.60 ± 3.13 in the control group, 1.60 ± 1.75 in the bubble-making group and 1.85 ± 1.42 in the breathing exercise group. The mean score of behavioral pain symptoms was 3.80 ± 2.80 in the control group, 1.15 ± 1.13 in the bubble-making group, and 0.96 ± 0.75 in the breathing exercise group. Results showed a significant difference in the mean pain scores (based on numeric scale and pain behavior scale) between the control group and other groups after the injection, but the difference in the mean pain scores between the two groups of experiment after the injection was not significant. CONCLUSIONS: According to the results of this study, both distraction methods of regular breathing exercise and bubble-making can reduce the pain of catheter insertion in children and since there was no difference between their effects, they can be used based on the individual child's interest. AU - Bagheriyan, Samaneh AU - Borhani, Fariba AU - Abbaszadeh, Abbas AU - Ranjbar, Hadi DA - 2011 DP - PubMed IS - 2 J2 - Iran J Nurs Midwifery Res KW - distraction Pain school-age children thalassemia LA - eng PY - 2011 SN - 2228-5504 SP - 174-180 ST - The effects of regular breathing exercise and making bubbles on the pain of catheter insertion in school age children T2 - Iranian Journal of Nursing and Midwifery Research TI - The effects of regular breathing exercise and making bubbles on the pain of catheter insertion in school age children UR - http://www.ncbi.nlm.nih.gov/pubmed/22224103 VL - 16 ID - 98 ER - TY - JOUR AB - Background: Suicide among adolescents in the United States is the second leading cause of death. Bullying victimization has also been identified as a growing public health concern. Although studies have examined the association between bullying victimization and mental health outcomes, there is a dearth of research investigating the association between bullying victimization and suicidal ideation among adolescents. Objective: The objective of this study is to investigate the association between bullying victimization and suicidal ideation among adolescents. Participants and Setting: Data for this study came from the 2017 National Youth Risk Behavior Survey. Methods: An analytic sample of 14,603 adolescents aged 14-18 years (52 % female) was analyzed using binary logistic regression. Results: About 18 % of adolescents experienced suicidal ideation during the past 12 months. About one in ten adolescents (9.1 %) were victims of both school bullying and cyberbullying. Bullying victimization was associated with suicidal ideation whereby, adolescents who experienced both school bullying and cyberbullying victimization had 3.26 times higher odds of experiencing suicidal ideation (AOR = 3.26, p < .001, 95 % CI = 3.10-3.43), adolescents who experienced school bullying victimization had 2.15 times higher odds of experiencing suicidal ideation (AOR = 2.15, p < .001, 95 % CI = 2.04-2.27), and adolescents who experienced cyberbullying victimization had twice the odds of experiencing suicidal ideation (AOR = 2.00, p < .001, 95 % CI =1.87-2.14). Other factors significantly associated with suicidal ideation include forced sexual intercourse, depressive symptoms, cigarette smoking, alcohol use, cannabis use, and illicit drug use. Conclusion: Understanding the association between bullying victimization and suicidal ideation could contribute to early identification of adolescents who may be at risk for suicide. AN - WOS:000520951800016 AU - Baiden, P. AU - Tadeo, S. K. C7 - 104417 DA - Apr DO - 10.1016/j.chiabu.2020.104417 N1 - Baiden, Philip Tadeo, Savarra K. Tadeo, Savarra/AAA-1007-2021 Baiden, Philip/0000-0003-3877-2594 1873-7757 PY - 2020 SN - 0145-2134 ST - Investigating the association between bullying victimization and suicidal ideation among adolescents: Evidence from the 2017 Youth Risk Behavior Survey T2 - Child Abuse & Neglect TI - Investigating the association between bullying victimization and suicidal ideation among adolescents: Evidence from the 2017 Youth Risk Behavior Survey UR - ://WOS:000520951800016 VL - 102 ID - 1833 ER - TY - JOUR AB - Migraine involves 5-10% of children and adolescents. Thirty percent of children with severe migraine attacks have school absence and reduced quality of life that need preventive therapy. The purpose of this randomised control trial study is to compare the effectiveness, safety and the tolerability of pregabalin toward Propranolol in migraine prophylaxis of children. From May 2011 to October 2012, 99 children 3-15 years referred to the neurology clinic of Mofid Children's Hospital with a diagnosis of migraine enrolled the study. Patients randomly divided into two groups (A&B). We treated children of group A with capsule of pregabalin as children of group B with tablet of propranolol for at least 8 weeks. In this study, 99 patients were examined that 91 children reached the last stage. The group A consistsed of 46 patients, 12(26.1%) girls, 34 (73.9%) boys and the group B consisted of 45 patients, 14(31.1%) girls, 31 (68.9%) boys. Basis of age, gender, headache onset, headache frequency, migraine type, triggering and relieving factors there was no significant difference among these groups (P>0.05). After 4 and 8 weeks of Pregabalin usage monthly headache frequency decreased to 2.2±4.5 and 1.76±6.2 respectively. Propranolol reduced monthly headache frequency up to 3.73±6.11 and 3.34±5.95 later 4 and 8 weeks respectively. There was a significant difference between these two groups according to headache frequency reduction (P=0.04). Pregabalin efficacy in reducing the frequency and duration of pediatric migraine headache is considerable in comparison with propranolol. AD - Bahrami Children Hospital, Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran. Dr.mkbakhshandehbali@yahoo.com. Department of Community Medicine, Research Development Center of Bahrami Children Hospital, Tehran University of Medical Sciences, Tehran, Iran. Dr.mkbakhshandehbali@yahoo.com. Department of Pediatrics, Kermanshah University of Medical Sciences, Kermanshah, Iran. Dr.mkbakhshandehbali@yahoo.com. Department of Pediatric Neurology, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Dr.mkbakhshandehbali@yahoo.com. AN - 26024701 AU - Bakhshandeh Bali, M. AU - Rahbarimanesh, A. A. AU - Sadeghi, M. AU - Sedighi, M. AU - Karimzadeh, P. AU - Ghofrani, M. DP - NLM ET - 2015/05/31 IS - 5 KW - Adolescent Child Child, Preschool Female Humans Male Migraine Disorders/*prevention & control Pregabalin/*therapeutic use Propranolol/*therapeutic use *Quality of Life LA - eng N1 - 1735-9694 Bakhshandeh Bali, MohammadKazem Rahbarimanesh, Ali Akbar Sadeghi, Manelie Sedighi, Mostafa Karimzadeh, Parvaneh Ghofrani, Mohammad Comparative Study Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't Iran Acta Med Iran. 2015;53(5):276-80. PY - 2015 SN - 0044-6025 SP - 276-80 ST - Comparison of propranolol and pregabalin for prophylaxis of childhood migraine: a randomised controlled trial T2 - Acta Med Iran TI - Comparison of propranolol and pregabalin for prophylaxis of childhood migraine: a randomised controlled trial VL - 53 ID - 3473 ER - TY - JOUR AB - AIM: To determine the prevalence of recurrent complaints of pain (RCP) in Greek children, and to examine associations with socio-demographic characteristics and psychosocial factors. METHODS: Cross-sectional study comprising a nationally representative population of 8130 7-y-old Greek schoolchildren. Data were collected by mailed questionnaires (response rate 89%). RCP was defined as present if at least one of the complaints of headache, abdominal pain or limb pain occurred at least once a week. RESULTS: The RCP prevalence rate was 7.2%, with significant gender differences (8.8% of girls, 5.7% of boys; p<0.001). RCP was significantly positively associated with a chronic health problem among the children, frequent change of residence, poor school performance, often watching TV and rarely playing with other children. There were no statistically significant associations of RCP with family structure and socio-economic status. CONCLUSION: The results are indicative of the prevalence of RCP in Greek schoolchildren. This study enlightens the psychosocial component of RCP and emphasizes the importance of gathering information on children's social background in medical settings. AD - First Department of Paediatrics, Aghia Sofia Children's Hospital, Athens, Greece. AN - 16882567 AU - Bakoula, C. AU - Kapi, A. AU - Veltsista, A. AU - Kavadias, G. AU - Kolaitis, G. DA - Aug DO - 10.1080/08035250600684453 DP - NLM ET - 2006/08/03 IS - 8 KW - Child Cross-Sectional Studies Female Greece/epidemiology Health Status Health Surveys Humans Life Style Male Pain/*epidemiology/psychology Prevalence Recurrence Residence Characteristics Risk Factors Sex Distribution Socioeconomic Factors LA - eng N1 - Bakoula, Chryssa Kapi, Aikaterini Veltsista, Alexandra Kavadias, George Kolaitis, Gerasimos Journal Article Norway Acta Paediatr. 2006 Aug;95(8):947-51. doi: 10.1080/08035250600684453. PY - 2006 SN - 0803-5253 (Print) 0803-5253 SP - 947-51 ST - Prevalence of recurrent complaints of pain among Greek schoolchildren and associated factors: a population-based study T2 - Acta Paediatr TI - Prevalence of recurrent complaints of pain among Greek schoolchildren and associated factors: a population-based study VL - 95 ID - 3544 ER - TY - JOUR AB - Objectives: Suicide is a leading cause of death; unfortunately most individuals at risk for suicide are not identified, assessed or treated by the mental health system. Investigating medical healthcare utilization among individuals with a history of suicide attempt may identify alternative settings for case finding and brief intervention. Methods: The study sample (n=1422, 58% female, 72% African-American) is from a prospective cohort of adults (27-31 years) who participated in a randomized trial of school-based interventions. Logistic regression evaluated the relationship between lifetime history of suicide attempt with past year medical service utilization and selected self-reported health conditions, controlling for lifetime Major Depressive Disorder (MDD), demographic factors, health insurance status and employment. Results: A suicide attempt history was associated with past year emergency department medical visits [aOR 1.51, 95% CI 1.04-2.18, P=.03], but not primary care visits or inpatient hospitalization, when controlling for MDD and other covariates. Severe headaches and chronic gastrointestinal conditions were also associated with lifetime suicide attempt [aOR 1.50, 95% CI 1.03-2.17 and aOR 1.67, 95% CI 1.06-2.63, respectively]. Conclusions: Suicide prevention, including universal screening and brief intervention, is indicated in emergency department settings. Restricting screening to subgroups, such as those individuals presenting with depression, may miss at-risk individuals with somatic concerns. (C) 2014 Elsevier Inc. All rights reserved. AN - WOS:000339333800015 AU - Ballard, E. D. AU - Cwik, M. AU - Storr, C. L. AU - Goldstein, M. AU - Eaton, W. W. AU - Wilcox, H. C. DA - Jul-Aug DO - 10.1016/j.genhosppsych.2014.03.004 IS - 4 N1 - Ballard, Elizabeth D. Cwik, Mary Storr, Carla L. Goldstein, Mitchell Eaton, William W. Wilcox, Holly C. Ballard, Elizabeth/O-6856-2017 Ballard, Elizabeth/0000-0001-5304-0127; Wilcox, Holly/0000-0003-2624-0654 1873-7714 PY - 2014 SN - 0163-8343 SP - 437-441 ST - Recent medical service utilization and health conditions associated with a history of suicide attempts T2 - General Hospital Psychiatry TI - Recent medical service utilization and health conditions associated with a history of suicide attempts UR - ://WOS:000339333800015 VL - 36 ID - 2299 ER - TY - JOUR AB - Considerable heterogeneity among pediatric chronic pain patients may at least partially explain the variability seen in the response to behavioral therapies. The current study tested whether autistic traits and attention-deficit/hyperactivity disorder (ADHD) symptoms in a clinical sample of children and adolescents with chronic pain are associated with socioemotional and functional impairments and response to acceptance and commitment therapy (ACT) treatment, which has increased psychological flexibility as its core target for coping with pain and pain-related distress. Children and adolescents aged 8-18 years (N = 47) were recruited. Patients and their parents completed questionnaires pre- and post-ACT of 17 sessions. Correlational analyses and mixed-effects models were used to assess the role of autistic traits and ADHD symptoms in pretreatment functioning and ACT-treatment response. Outcome variables were degree to which pain interfered with daily activities (i.e., pain interference, sleep, and physical and school functioning), socioemotional functioning (i.e., depressive symptoms, emotional, and social functioning), psychological inflexibility, and pain intensity. Autistic traits and ADHD symptoms, pain frequency, and pain duration were measured at pretreatment only. Higher autistic traits were associated with greater pain interference, higher depression, and greater psychological inflexibility. Higher ADHD symptomatology was associated with greater pretreatment pain interference, lower emotional functioning, greater depression, and longer duration of pain. Across patients, all outcome variables, except for sleep disturbances and school functioning, significantly improved from pre- to post-ACT. Higher autistic traits were associated with greater pre- to post-ACT improvements in emotional functioning and sleep disturbance and non-significant improvements in pain interference. ADHD symptomatology was not associated with treatment outcome. The current results showed that neuropsychiatric symptoms in pediatric chronic pain patients are associated with lower functioning, particularly pain interfering with daily life and lower socioemotional functioning. The results suggest that not only pediatric chronic pain patients low in neuropsychiatric symptoms may benefit from ACT, but also those high in autism traits and ADHD symptoms. With the present results in mind, pediatric chronic pain patients higher in autistic traits may actually derive extra benefit from ACT. Future research could assess whether increased psychological flexibility, the core focus of ACT, enabled those higher in autism traits to cope relatively better with pain-related distress and thus to gain more from the treatment, as compared to those lower in autism traits. Moreover, to address specific effects of ACT, inclusion of an appropriate control group is key. AN - WOS:000642300500001 AU - Balter, L. J. T. AU - Lipsker, C. W. AU - Wicksell, R. K. AU - Lekander, M. C7 - 576943 DA - Apr DO - 10.3389/fpsyg.2021.576943 N1 - Balter, Leonie J. T. Wiwe Lipsker, Camilla Wicksell, Rikard K. Lekander, Mats PY - 2021 SN - 1664-1078 ST - Neuropsychiatric Symptoms in Pediatric Chronic Pain and Outcome of Acceptance and Commitment Therapy T2 - Frontiers in Psychology TI - Neuropsychiatric Symptoms in Pediatric Chronic Pain and Outcome of Acceptance and Commitment Therapy UR - ://WOS:000642300500001 VL - 12 ID - 1740 ER - TY - JOUR AB - PURPOSE: The purpose of this research was to describe 24-42 month outcomes of a combined inpatient/day hospital interdisciplinary pain rehabilitation program for children and adolescents with chronic pain and functional disability. METHODS: One-hundred-seventy-three children and adolescents (mean age=15.1 years, SD=2.5) were treated in the three-week program. Mixed effects regression models (MERM) examined changes over time in pain ratings (0-10), school days missed by children and work days missed by parents in the preceding week, and the number of days hospitalized in the preceding month. RESULTS: Participants reported a significant decline in pain from admission to 24-42 month follow-up. The largest declines in pain occurred from discharge to 1-month follow-up (6.20 vs. 4.81 on a 0-10 numerical rating scale) and from 12 months to 24-42 month follow-up (4.90 vs. 3.56). Two distinct trajectories of treatment response were identified using growth mixture modeling: children with initially high pain ratings exhibited large reductions in pain ratings, while those with lower pain ratings at admission showed minimal reductions. Treatment resulted in significant reductions in school and work days missed and the number of days hospitalized (all p's < 0.001), with reductions evident at 1-month follow-up and maintained through 24-42 month follow-up. CONCLUSIONS: These results suggest that interdisciplinary pain rehabilitation is a promising approach to chronic pain and associated disability in children, with enduring improvements found 24-42 months following program completion. Distinct trajectories of treatment response were identified. AD - Pediatric Pain Rehabilitation Program, Cleveland Clinic, Cleveland, OH, USA Center for Pediatric Behavioral Health, Cleveland Clinic, Cleveland, OH, USA Department of Developmental and Rehabilitation Pediatrics, Cleveland Clinic, Cleveland, OH, USA. Pediatric Pain Rehabilitation Program, Cleveland Clinic, Cleveland, OH, USA. Pediatric Pain Rehabilitation Program, Cleveland Clinic, Cleveland, OH, USA Department of Developmental and Rehabilitation Pediatrics, Cleveland Clinic, Cleveland, OH, USA. Pediatric Pain Rehabilitation Program, Cleveland Clinic, Cleveland, OH, USA Center for Pediatric Behavioral Health, Cleveland Clinic, Cleveland, OH, USA. AN - 25260503 AU - Banez, G. A. AU - Frazier, T. W. AU - Wojtowicz, A. A. AU - Buchannan, K. AU - Henry, D. E. AU - Benore, E. DO - 10.3233/prm-140289 DP - NLM ET - 2014/09/28 IS - 3 KW - Adolescent Child Chronic Pain/*rehabilitation Cohort Studies Disabled Children/*rehabilitation Female Humans Inpatients Longitudinal Studies Male Patient Care Team/*organization & administration Reaction Time Regression Analysis Treatment Outcome Adolescents interdisciplinary health team outcomes assessment pain rehabilitation LA - eng N1 - 1875-8894 Banez, Gerard A Frazier, Thomas W Wojtowicz, Andrea A Buchannan, Kristen Henry, Douglas E Benore, Ethan Journal Article Research Support, Non-U.S. Gov't Netherlands J Pediatr Rehabil Med. 2014;7(3):197-206. doi: 10.3233/PRM-140289. PY - 2014 SN - 1874-5393 SP - 197-206 ST - Chronic pain in children and adolescents: 24-42 month outcomes of an inpatient/day hospital interdisciplinary pain rehabilitation program T2 - J Pediatr Rehabil Med TI - Chronic pain in children and adolescents: 24-42 month outcomes of an inpatient/day hospital interdisciplinary pain rehabilitation program VL - 7 ID - 3211 ER - TY - JOUR AB - BACKGROUND CONTEXT: Back problems are reported with increasing frequency in adults and adolescents. Most information is from self-reported questionnaires or studies with small sample sizes. Reports were usually focused on specific diseases and biased toward overdiagnosis. PURPOSE: To assess the prevalence of common back disorders among a large cohort of 17-year-old males and females recruited by the Israel Defense Forces (IDF). STUDY DESIGN: A retrospective cross-sectional prevalence study. PATIENT SAMPLE: Seventeen-year-old Israeli male and female military recruits reporting as directed by the IDF for preinduction medical examination between January 01, 1998 and December 31, 2006. OUTCOME MEASURES: Military functional limitation Grades 1 to 7 per diagnosis category. METHODS: Military recruits were examined and classified based on medical and orthopedic diagnoses. They were referred for orthopedic consultation as necessary. Four orthopedic classifications were used: spinal deformity (including kyphosis and scoliosis), back pain (including neck and radicular syndromes), spondylolysis/olisthesis, and limitations resulting from trauma or spinal surgery. Data were coded into a central database, and descriptive statistics are presented. RESULTS: The overall prevalence of back disorders among 828,171 17-year-old military recruits (61.5% male) was 16.8%. Back disorders resulting in significant functional limitation were diagnosed in 0.8% of recruits. The most prevalent diagnoses were spinal deformities (kyphosis and scoliosis, females 11.9%, males 11.5%) and back pain (females 3.0%, males 5.6%). Most of these diagnoses were rated as mild. CONCLUSIONS: When using objective criteria, overall back disorders in a large population of 17-year-old recruits were 17%, considerably lower than most reports. Back morbidity severe enough to prevent combat duty occurred at a rate of less than 1%, suggesting that serious back morbidity is not a frequent finding in this age group. LEVEL OF EVIDENCE: Symptom prevalence study, Level III. (C) 2012 Elsevier Inc. All rights reserved. AN - WOS:000309527900005 AU - Bar-Dayan, Y. AU - Morad, Y. AU - Elishkevitz, K. P. AU - Bar-Dayan, Y. AU - Finestone, A. S. DA - Sep DO - 10.1016/j.spinee.2010.04.009 IS - 9 N1 - Bar-Dayan, Yosefa Morad, Yair Elishkevitz, Keren Politi Bar-Dayan, Yaron Finestone, Aharon S. Finestone, Aharon S/R-9001-2019 Finestone, Aharon S/0000-0003-1956-5557 1878-1632 Si PY - 2012 SN - 1529-9430 SP - 749-755 ST - Back disorders among Israeli youth: a prevalence study in young military recruits T2 - Spine Journal TI - Back disorders among Israeli youth: a prevalence study in young military recruits UR - ://WOS:000309527900005 VL - 12 ID - 2417 ER - TY - JOUR AB - We report the outcome of 19 children aged 5.2 to 13.2 years with 20 fractures of the femoral shaft requiring surgery, who were randomly assigned to have external fixation (EF) or flexible intramedullary nailing (FIN) (10 fractures each). The duration of the operation averaged 56 minutes for the EF group with 1.4 minutes of fluoroscopy, compared with 74 minutes and 2.6 minutes, respectively, for the FIN group. The early postoperative course was similar, but the FIN [corrected] group showed much more callus formation. The time to full weight-bearing, full range of movement and return to school were all shorter in the FIN group. The FIN complications included one transitory foot drop and two cases of bursitis at an insertion site. In the EF group there was one refracture, one rotatory malunion requiring remanipulation and two pin-track infections. At an average follow-up of 14 months two patients in the EF group had mild pain, four had quadriceps wasting, one had leg-length discrepancy of over 1 cm, four had malalignment of over 5 degrees, and one had limited hip rotation. In the FIN group, one patient had mild pain and one had quadriceps wasting; there were no length discrepancies, malalignment or limitation of movement. Parents of the FIN group were more satisfied. We recommend the use of flexible intramedullary nailing for fractures of the femoral shaft which require surgery, and reserve external fixation for open or severely comminuted fractures. AD - Hadassah Medical Centre, Jerusalem, Israel. AN - 9393916 AU - Bar-On, E. AU - Sagiv, S. AU - Porat, S. DA - Nov DO - 10.1302/0301-620x.79b6.7740 DP - NLM ET - 1997/12/11 IS - 6 KW - Absenteeism Adolescent Bone Malalignment/etiology Bone Nails/adverse effects Bony Callus/physiopathology Bursitis/etiology Child Child, Preschool Equipment Design *External Fixators/adverse effects Femoral Fractures/*surgery Fluoroscopy Follow-Up Studies Foot Diseases/etiology Fracture Fixation/adverse effects/*instrumentation *Fracture Fixation, Intramedullary/adverse effects/instrumentation Fracture Healing Humans Leg Length Inequality/etiology Movement Muscular Atrophy/etiology Pain, Postoperative/etiology Patient Satisfaction Prospective Studies Radiography, Interventional Recurrence Surgical Wound Infection/etiology Time Factors Weight-Bearing LA - eng N1 - Bar-On, E Sagiv, S Porat, S Clinical Trial Comparative Study Journal Article Randomized Controlled Trial England J Bone Joint Surg Br. 1997 Nov;79(6):975-8. doi: 10.1302/0301-620x.79b6.7740. PY - 1997 SN - 0301-620X (Print) 0301-620x SP - 975-8 ST - External fixation or flexible intramedullary nailing for femoral shaft fractures in children. A prospective, randomised study T2 - J Bone Joint Surg Br TI - External fixation or flexible intramedullary nailing for femoral shaft fractures in children. A prospective, randomised study VL - 79 ID - 3504 ER - TY - JOUR AB - Children with sickle cell disease (SCD) are at risk for poor health-related quality of life (HRQOL). The current analysis sought to explore parent problem-solving abilities/skills as a moderator between SCD complications and HRQOL to evaluate applicability to pediatric SCD. At baseline, 83 children ages 6-12 years and their primary caregiver completed measures of child HRQOL. Primary caregivers also completed a measure of social problem-solving. A SCD complications score was computed from medical record review. Parent problem-solving abilities significantly moderated the association of SCD complications with child self-report psychosocial HRQOL (p = .006). SCD complications had a direct effect on parent proxy physical and psychosocial child HRQOL. Enhancing parent problem-solving abilities may be one approach to improve HRQOL for children with high SCD complications; however, modification of parent perceptions of HRQOL may require direct intervention to improve knowledge and skills involved in disease management. AN - WOS:000331958200006 AU - Barakat, L. P. AU - Daniel, L. C. AU - Smith, K. AU - Robinson, M. R. AU - Patterson, C. A. DA - Mar DO - 10.1007/s10880-013-9379-7 IS - 1 N1 - Barakat, Lamia P. Daniel, Lauren C. Smith, Kelsey Robinson, M. Renee Patterson, Chavis A. Daniel, Lauren/AAA-3700-2021 Daniel, Lauren/0000-0002-8637-2424 1573-3572 PY - 2014 SN - 1068-9583 SP - 56-65 ST - Parental Problem-Solving Abilities and the Association of Sickle Cell Disease Complications with Health-Related Quality of Life for School-Age Children T2 - Journal of Clinical Psychology in Medical Settings TI - Parental Problem-Solving Abilities and the Association of Sickle Cell Disease Complications with Health-Related Quality of Life for School-Age Children UR - ://WOS:000331958200006 VL - 21 ID - 2317 ER - TY - JOUR AB - The importance of the use of analgesic medication for the symptomatic relief of pain has been underestimated in medical practice. The objective of this study was to determine the prevalence of tension-type and migraine-type headaches and the associated analgesic consumption for its treatment within elementary school students from Porto Alegre (Brazil). A systematic random sample of 538 students from 5th to 8th grades was produced to complete the cross-sectional delineation. Subjects were individually submitted to a structured interview on headache and to general physical and neurological examination. Lifetime prevalence for headaches was 93.3%, 82.9% of the students recalled having headaches during the last year and 31.4% reported headaches in the last week. The prevalence for headaches in the previous 24 h was 8.9%. There was a significant prevalence of headache in females. The prevalence of analgesic consumption was 84.1% throughout life, 85.7% in the last year, and 54% in the last 3 months. A significantly higher prevalence of headache medication consumption was also depicted for females. However, the small age differences within the sample did not appear to be an important factor in influencing analgesic use for headaches. Different agents composed the individual treatment of headaches, with predominant use of over-the-counter preparations. Acetylsalicylic acid, consumed by 58.3% of the children, was the drug most frequently used for both tension-type and migraine-type headache treatments. In spite of the verification that headache was very frequently experienced by the children composing this sample accompanied by a consequent use of analgesics, no medication abuse was diagnosed. (C) 1997 John Wiley & Sons, Ltd. AN - WOS:A1997YF04200007 AU - Barea, L. M. AU - Rotta, N. T. AU - Stein, A. AU - Barros, H. M. T. AU - Tannhauser, M. DA - Sep-Oct IS - 5 N1 - Barea, LM Rotta, NT Stein, A Barros, HMT Tannhauser, M AT, Stein/AAD-8391-2020; Barros, Helena MT/I-4802-2014 AT, Stein/0000-0002-8756-8699; Barros, Helena MT/0000-0002-0779-7732 PY - 1997 SN - 1053-8569 SP - 359-366 ST - Analgesic use for headache treatment by schoolchildren of southern Brazil T2 - Pharmacoepidemiology and Drug Safety TI - Analgesic use for headache treatment by schoolchildren of southern Brazil UR - ://WOS:A1997YF04200007 VL - 6 ID - 2906 ER - TY - JOUR AB - Objective. To develop a valid and reliable measure of arthritis self-efficacy for use with school-age children with juvenile idiopathic arthritis (JIA). Methods. Construction of the 11-item Children's Arthritis Self-Efficacy Scale (CASE) was based on an existing body of knowledge and the results of focus groups with children, their parents, and health professionals. Data for validation of the CASE were collected by self-administered questionnaires completed by 89 children and 151 caregivers. Results. Analyses revealed a 3-factor structure relating to self-efficacy for managing symptoms, emotional consequences, and activities, explaining 76.5% of the total variance. The CASE demonstrated high internal consistency, concurrent validity, and construct validity. Conclusion. Preliminary findings suggest that the CASE is worthy of further psychometric testing and may have the potential to help delineate variations in adjustment among children with JIA. AN - WOS:000171872400009 AU - Barlow, J. H. AU - Shaw, K. L. AU - Wright, C. C. DA - Apr DO - 10.1002/1529-0131(200104)45:2<159::Aid-anr169>3.3.Co;2-u IS - 2 N1 - Barlow, JH Shaw, KL Wright, CC 1529-0131 PY - 2001 SN - 0004-3591 SP - 159-166 ST - Development and preliminary validation of a children's arthritis self-efficacy scale T2 - Arthritis & Rheumatism-Arthritis Care & Research TI - Development and preliminary validation of a children's arthritis self-efficacy scale UR - ://WOS:000171872400009 VL - 45 ID - 2850 ER - TY - JOUR AB - The purpose of this research was to analyze the oral health status of youth housed in socio-educational centers of the Juvenile Penal Area of the Province of Córdoba, Argentina of corrections by considering clinical evaluation and the main sociodemographic data. Socio-demographics, healthy and unhealthy habits of self-care, and dental clinical profile were assessed for this purpose. An exploratory cross-sectional study was carried out on 70 14- to 18-year-olds who had been institutionalized for at least six months. A clinical examination was conducted and the WHO Oral Health Survey was applied. Centralization and dispersion measurements, relative frequency, multiple correspondence analysis and generalized linear models were used to describe the data. The results showed: males 94%, mean age 16.91 ± 1.11, complete primary schooling 34%, from Córdoba City 69% and belonging to nuclear families 29%. Regarding healthy habits, 71% had frequent sugar intake, and 46% brushed teeth daily; while among unhealthy habits, 80% smoked tobacco, 63% drankalcohol and 73% used psychoactive substances. Sixty-three percent had visited a dentist once, and in 80% of the cases reason for the visit was pain. Clinical examination showed high prevalence of deterioration of the oral health component (DMFT = 8.94 ± 4.75, SiC = 14.26 ± 2.15, IPC3 = 56%, MO = 53%). Clinical profile showed marked prevalence of a very high level of caries severity, gingival disease and malocclusion, but not of initial stages of caries, alterations of enamel or temporomandibular dysfunction. The socio-demographic characteristics revealed conditions of social, educational and health vulnerability, a situation which interferes with the inclusion of these youths in the productive system and their access to better living conditions. AD - Universidad Nacional de Córdoba, Facultad de Odontología, Grupo de Investigación Interdisciplinario "Promoción Contextualizada", Argentina. marcebarnetche@gmail.com. Universidad Nacional de Córdoba, Facultad de Odontología, Grupo de Investigación Interdisciplinario "Promoción Contextualizada", Argentina. AN - 29750237 AU - Barnetche, M. M. AU - Cornejo, L. S. DA - Dec DP - NLM ET - 2018/05/12 IS - 3 KW - Adolescent Argentina Cross-Sectional Studies Female Humans Institutionalization Male *Oral Health Social Control, Formal Socioeconomic Factors Oral health Vulnerable populations LA - eng N1 - 1852-4834 Barnetche, María M Cornejo, Lila S Journal Article Argentina Acta Odontol Latinoam. 2017 Dec;30(3):129-140. OP - Salud bucal de jóvenes alojados en centros socioeducativos del Área Penal Juvenil de la Provincia de Córdoba, Argentina. PY - 2017 SN - 0326-4815 SP - 129-140 ST - Oral health of youth housed in socio-educational centers of the Juvenile Penal Area of the Province of Córdoba, Argentina T2 - Acta Odontol Latinoam TI - Oral health of youth housed in socio-educational centers of the Juvenile Penal Area of the Province of Córdoba, Argentina VL - 30 ID - 4033 ER - TY - JOUR AB - Sickle cell disease (SCD) occurs in 1 of every 400 to 500 African American births. Despite its prevalence, there has been a relative dearth of attention paid to SCD in the psychological literature. African American SCD adolescents and young adults, individuals at an already vulnerable developmental stage, are at increased risk for psychological distress and psychosocial impairments (e.g, depression and low self-esteem, poor social and academic/vocational functioning). Such difficulties often result in problematic adherence to medical regimens, and thus represent a potentially serious clinical and public health problem that merits the attention of psychologists working in medical settings. This article (I) reviews the psychosocial needs peculiar to SCD patients transitioning from adolescence to young adulthood; (2) applies a culturally informed stress-coping-adjustment framework to assess and address the psychological status, psychosocial functioning and disease outcomes of these individuals; and (3) describes a culturally and developmentally sensitive, psychoeducational group intervention. AN - WOS:000076301400007 AU - Baskin, M. L. AU - Collins, M. H. AU - Brown, F. AU - Griffith, J. R. AU - Samuels, D. AU - Moody, A. AU - Thompson, M. P. AU - Eckman, J. AU - Kaslow, N. J. DA - Sep DO - 10.1023/a:1026206204009 IS - 3 N1 - Baskin, ML Collins, MH Brown, F Griffith, JR Samuels, D Moody, A Thompson, MP Eckman, J Kaslow, NJ moody, alan/M-9258-2019 1573-3572 PY - 1998 SN - 1068-9583 SP - 315-341 ST - Psychosocial considerations in sickle cell disease (SCD): The transition from adolescence to young adulthood T2 - Journal of Clinical Psychology in Medical Settings TI - Psychosocial considerations in sickle cell disease (SCD): The transition from adolescence to young adulthood UR - ://WOS:000076301400007 VL - 5 ID - 2891 ER - TY - JOUR AB - P001 - Sepsis impairs the capillary response within hypoxic capillaries and decreases erythrocyte oxygen-dependent ATP efflux R. M. Bateman, M. D. Sharpe, J. E. Jagger, C. G. Ellis P002 - Lower serum immunoglobulin G2 level does not predispose to severe flu. J. Solé-Violán, M. López-Rodríguez, E. Herrera-Ramos, J. Ruíz-Hernández, L. Borderías, J. Horcajada, N. González-Quevedo, O. Rajas, M. Briones, F. Rodríguez de Castro, C. Rodríguez Gallego P003 - Brain protective effects of intravenous immunoglobulin through inhibition of complement activation and apoptosis in a rat model of sepsis F. Esen, G. Orhun, P. Ergin Ozcan, E. Senturk, C. Ugur Yilmaz, N. Orhan, N. Arican, M. Kaya, M. Kucukerden, M. Giris, U. Akcan, S. Bilgic Gazioglu, E. Tuzun P004 - Adenosine a1 receptor dysfunction is associated with leukopenia: A possible mechanism for sepsis-induced leukopenia R. Riff, O. Naamani, A. Douvdevani P005 - Analysis of neutrophil by hyper spectral imaging - A preliminary report R. Takegawa, H. Yoshida, T. Hirose, N. Yamamoto, H. Hagiya, M. Ojima, Y. Akeda, O. Tasaki, K. Tomono, T. Shimazu P006 - Chemiluminescent intensity assessed by eaa predicts the incidence of postoperative infectious complications following gastrointestinal surgery S. Ono, T. Kubo, S. Suda, T. Ueno, T. Ikeda P007 - Serial change of c1 inhibitor in patients with sepsis – A prospective observational study T. Hirose, H. Ogura, H. Takahashi, M. Ojima, J. Kang, Y. Nakamura, T. Kojima, T. Shimazu P008 - Comparison of bacteremia and sepsis on sepsis related biomarkers T. Ikeda, S. Suda, Y. Izutani, T. Ueno, S. Ono P009 - The changes of procalcitonin levels in critical patients with abdominal septic shock during blood purification T. Taniguchi, M. O P010 - Validation of a new sensitive point of care device for rapid measurement of procalcitonin C. Dinter, J. Lotz, B. Eilers, C. Wissmann, R. Lott P011 - Infection biomarkers in primary care patients with acute respiratory tract infections – Comparison of procalcitonin and C-reactive protein M. M. Meili, P. S. Schuetz P012 - Do we need a lower procalcitonin cut off? H. Hawa, M. Sharshir, M. Aburageila, N. Salahuddin P013 - The predictive role of C-reactive protein and procalcitonin biomarkers in central nervous system infections with extensively drug resistant bacteria V. Chantziara, S. Georgiou, A. Tsimogianni, P. Alexandropoulos, A. Vassi, F. Lagiou, M. Valta, G. Micha, E. Chinou, G. Michaloudis P014 - Changes in endotoxin activity assay and procalcitonin levels after direct hemoperfusion with polymyxin-b immobilized fiber A. Kodaira, T. Ikeda, S. Ono, T. Ueno, S. Suda, Y. Izutani, H. Imaizumi P015 - Diagnostic usefullness of combination biomarkers on ICU admission M. V. De la Torre-Prados, A. Garcia-De la Torre, A. Enguix-Armada, A. Puerto-Morlan, V. Perez-Valero, A. Garcia-Alcantara P016 - Platelet function analysis utilising the PFA-100 does not predict infection, bacteraemia, sepsis or outcome in critically ill patients N. Bolton, J. Dudziak, S. Bonney, A. Tridente, P. Nee P017 - Extracellular histone H3 levels are inversely correlated with antithrombin levels and platelet counts and are associated with mortality in sepsis patients G. Nicolaes, M. Wiewel, M. Schultz, K. Wildhagen, J. Horn, R. Schrijver, T. Van der Poll, C. 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Meissonnier P023 - Diagnosing sepsis in 5 minutes: Nanofluidic technology study with pancreatic-stone protein (PSP/ reg) L. Girard, F. Rebeaud P024 - How nanotechnology-based approaches could contribute to sepsis prevention, diagnosis and treatment I. Herrmann P025 - Il7r transcriptional expression analysis during septic shock B. Delwarde, E. Peronnet, E. Cerrato, F. Venet, A. Lepape, T. Rimmelé, G. Monneret, J. Textoris P026 - Disbalance of microbial metabolites of aromatic acids affects the severity in critically ill patients N. Beloborodova, V. Moroz, A. Osipov, A. Bedova, Y. Sarshor, A. Pautova, A. Sergeev, E. Chernevskaya P027 - Copeptin predicts 10-year all-cause mortality in community patients J. Odermatt, R. Bolliger, L. Hersberger, M. Ottiger, M. Christ-Crain, B. Mueller, P. Schuetz P028 - Identification of differential proteomic response in septic patients secondary to community and hospital acquired pneumonia N. K. Sharma, A. K. Tashima, M. K. Brunialti, F. R. Machado, M. Assuncao, O. Rigato, R. Salomao P029 - Monocyte HLA-DR expression in community-acquired bacteremic sepsis - dynamics associated to aetiology and prediction of secondary sepsis S. C. Cajander, G. Rasmussen, E. Tina, B. Söderquist, J. Källman, K. Strålin P030 - Soluble B- and T-lymphocyte attenuator: A possible prognostic marker in sepsis A. L. Lange, J. S. Sundén-Cullberg, A. M. Magnuson, O. H. Hultgren P031 - Fractal dimension: A new biomarker for quantifying clot microstructure in patients across the sepsis spectrum G. Davies, S. Pillai, G. Mills, R. Aubrey, K. Morris, P. Williams, P. Evans P032 - Comparison between the new biomarker for coagulation, clot microstructure (Df) with rotational thromboelastometry (ROTEM) in patients across the sepsis spectrum S. Pillai, G. Davies, G. Mills, R. Aubrey, K. Morris, P. Williams, P. Evans P033 - Changes in fibrinolysis across the sepsis spectrum: The use of rotational thromboelastometry (ROTEM) lysis index (LI60) and D-Dimer concentration S. Pillai, G. Davies, G. Mills, R. Aubrey, K. Morris, P. Williams, P. Evans P034 - The intensive care infection score – a promising marker for the prediction of infection and its severity. P. Van der Geest, M. Mohseni, J. Linssen, R. De Jonge, S. Duran, J. Groeneveld P035 - Challenges in the clinical diagnosis of sepsis R. Miller III, B. K. Lopansri, L. C. McHugh, A. Seldon, J. P. Burke P036 - Does zero heat flux thermometry more accurately identify sepsis on intensive care? J. Johnston, R. Reece-Anthony, A. Bond, A. Molokhia P037 - Advancing quality (AQ) sepsis programme: Improving early identification & treatment of sepsis in North West England. C. Mcgrath, E. Nsutebu P038 - Prehospital transport of acute septic patients P. Bank Pedersen, D. Pilsgaard Henriksen, S. Mikkelsen, A. Touborg Lassen P039 - Vasodilatory plant extracts gel as an alternative treatment for fever in critically ill patients R. Tincu, C. Cobilinschi, D. Tomescu, Z. Ghiorghiu, R. Macovei P040 - Host response and outcome of hypothermic sepsis M. A. Wiewel, M. B. Harmon, L. A. Van Vught, B. P. Scicluna, A. J. Hoogendijk, J. Horn, A. H. Zwinderman, O. L. Cremer, M. J. Bonten, M. J. Schultz, T. Van der Poll, N. P. Juffermans, W. J. Wiersinga P041 - Septic shock alert over SIRS criteria has an impact on outcome but needs to be revised G. Eren, Y Tekdos, M. Dogan, O. Acicbe, E. Kaya, O. Hergunsel P042 - Association between previous prescription of βblockers and mortality rate among septic patients: A retrospective observational study S. Alsolamy, G. Ghamdi, L. Alswaidan, S. Alharbi, F. Alenezi, Y. Arabi P043 - Recognition and treatment of sepsis on labour ward– teaching & information resources can improve knowledge J. Heaton, A. Boyce, L. Nolan, J. Johnston, A. Dukoff-Gordon, A. Dean, A. Molokhia P044 - Culture negative sepsis in the ICU – what is unique to this patient population? T. Mann Ben Yehudah P045 - Organ dysfunction in severe sepsis patients identified in administrative data in Germany, 2007-2013 C. Fleischmann, D. Thomas-Rueddel, C. Haas, U. Dennler, K. Reinhart P046 - A comparison of residents’ knowledge regarding; the Surviving Sepsis Campaign 2012 guideline O. Suntornlohanakul, B. Khwannimit P047 - Effectiveness of a septic shock bundle to improve outcomes in the ICU F. Breckenridge, A. Puxty P048 - Dose of norepinephrine in the first 24 hours as a parameter evaluating the effectiveness of treatment in patients with severe sepsis and septic shock P. Szturz, P. Folwarzcny, J. Svancara, R. Kula, P. Sevcik P049 - Norepinephrine or vasopressin + norepinephrine in septic shock. A retrospective series of 39 patients L. Caneva, A. Casazza, E. Bellazzi, S. Marra, L. Pagani, M. Vetere, R. Vanzino, D. Ciprandi, R. Preda, R. Boschi, L. Carnevale P050 - Methylene blue effectiveness as contributory treatment in patients with septic shock V. Lopez, M. Aguilar Arzapalo, L. Barradas, A. Escalante, J. Gongora, M. Cetina P051 - Coagulation disorders in patients with severe sepsis and DIC evaluated with thromboelastometry. B Adamik, D Jakubczyk, A Kübler P052 - Frequency and outcome of early sepsis-associated coagulopathy A. Radford, T. Lee, J. Singer, J. Boyd, D. Fineberg, M. Williams, J. Russell P053 - Assessment of coagulopathy in cancer patients with severe sepsis or septic shock. A case-control pilot study E. Scarlatescu, D. Tomescu, G. Droc, S. Arama P054 - Thromboelastometry in critically ill patients with disseminated intravascular coagulation M. Müller, M. Straat, S. S. Zeerleder, N. P. Juffermans P055 - Cessation of a preexisting chronic antiplatelet therapy is associated with increased mortality rates in severe sepsis and septic shock C. F. Fuchs, C. S. Scheer, S. W. Wauschkuhn, M. V. Vollmer, K. M. Meissner, S. K. Kuhn, K. H. Hahnenkamp, S. R. Rehberg, M. G. Gründling P056 - Neutrophil Extracellular Traps (NETs) production under hypoxic condition N. Yamamoto, M. Ojima, S. Hamaguchi, T. Hirose, Y. Akeda, R. Takegawa, O. Tasaki, T. Shimazu, K. Tomono P057 - Impact of ultraviolet air sterilizer in intensive care unit room, and clinical outcomes of patients E. Gómez-Sánchez, M. Heredia-Rodríguez, E. Álvarez-Fuente, M. Lorenzo-López, E. Gómez-Pesquera, M. Aragón-Camino, P. Liu-Zhu, A. Sánchez-López, A. Hernández-Lozano, M. T. Peláez-Jareño, E. Tamayo P058 - Focus of infection in severe sepsis - comparison of administrative data and prospective cohorts from Germany D. O. Thomas-Rüddel, C. Fleischmann, C. Haas, U. Dennler, K. Reinhart P059 - “Zero CLABSI” – can we get there? Obstacles on the 4 year journey and our strategies to overcome them – experience from an Indian ICU V. Adora, A. Kar, A. Chakraborty, S. Roy, A. Bandyopadhyay, M. Das P060 - Novel molecular techniques to identify central venous catheter (CVC) associated blood stream infections (BSIs) T. Mann Ben Yehudah, G. Ben Yehudah, M. Salim, N. Kumar, L. Arabi, T. Burger, P. Lephart, E. Toth-martin P061 - Zero clabsi” – can we get there? Obstacles on the 4 year journey and our strategies to overcome them – experience from an Indian ICU R. Rao, A. Kar, A. Chakraborty P062 - Prevention of central line-associated bloodstream infections in intensive care units: An international online survey C. Valencia, N. Hammami, S. Blot, J. L. Vincent, M. L. Lambert P063 - 30 days antimicrobial efficacy of non-leaching central venous catheters J. Brunke, T. Riemann, I. Roschke P064 - Efficacy of noble metal alloy-coated catheter in prevention of bacteriuria R. Tincu, C. Cobilinschi, D. Tomescu, Z. Ghiorghiu, R. Macovei P065 - Predicting bacteremic urinary tract infection in community setting: A prospective observational study S. Nimitvilai, K. Jintanapramote, S. Jarupongprapa P066 - Eight-year analysis of acinetobacter spp. monobacteremia in surgical and medical intensive care units at university hospital in Lithuania D. Adukauskiene, D. Valanciene P067 - Group A and group B streptococcal infections in intensive care unit – our experience in a tertiary centre G. Bose, V. Lostarakos, B. Carr P068 - Improved detection of spontaneous bacterial peritonitis by uritop + tm strip test and inoculation of blood culture bottles with ascitic fluid S. Khedher, A. Maaoui, A. Ezzamouri, M. Salem P069 - Increased risk of cellulitis in patients with congestive heart failure: a population based cohort study J. Chen P070 - Outcomes of severe cellulitis and necrotizing fasciitis in the critically ill D. R. Cranendonk, L. A. Van Vught, M. A. Wiewel, O. L. Cremer, J. Horn, M. J. Bonten, M. J. Schultz, T. Van der Poll, W. J. Wiersinga P071 - Botulism outbreak associated with people who inject drugs (PWIDs) in Scotland. M. Day, G. Penrice, K. Roy, P. Robertson, G. Godbole, B. Jones, M. Booth, L. Donaldson P072 - Surveillance of ESBL-producing enterobacteriaceae fecal carriers in the ICU Y. Kawano, H. Ishikura P073 - Prevalence of ESBL and carbapenemase producing uropathogens in a newly opened hospital in south India S. Sreevidya, N. Brahmananda Reddy, P. Muraray Govind, R. Pratheema, J. Devachandran Apollo Speciality Hospital - OMR, Chennai, India P074 - Prevalence, risk factors and outcomes of methicillin-resistant staphylococcus aureus nasal colonization in critically ill patients H. Al-Dorzi, M. Almutairi, B. Alhamadi, A. Crizaldo Toledo, R. Khan, B. Al Raiy, Y. Arabi P075 - Multidrug-resistant Acinetobacter baumannii infection in intensive care unit patients in a hospital with building construction: Is there an association? H. Talaie P076 - Multidrug-resistant organisms in a Dutch ICU J. A. Van Oers, A. Harts, E. Nieuwkoop, P. Vos P077 - Epidemiology and risk factors of ICU acquired infections caused by multidrug-resistant gram negative bacilli Y. Boussarsar, F. Boutouta, S. Kamoun, I. Mezghani, S. Koubaji, A. Ben Souissi, A. Riahi, M. S. Mebazaa P078 - Improving outcomes of severe infections by multidrug-resistant pathogens with polyclonal IgM-enriched immunoglobulins E. Giamarellos-Bourboulis, N. Tziolos, C. Routsi, C. Katsenos, I. Tsangaris, I. Pneumatikos, G. Vlachogiannis, V. Theodorou, A. Prekates, E. Antypa, V. Koulouras, N. Kapravelos, C. Gogos, E. Antoniadou, K. Mandragos, A. Armaganidis P079 - Must change the medical practice in ICU? A. R. Robles Caballero, B. Civantos, J. C. Figueira, J. López P080 - Mediterranean spotted fever in an infectious diseases intensive care unit A. Silva-Pinto, F. Ceia, A. Sarmento, L. Santos P081 - Clinical features and outcomes of patients with Middle East respiratory syndrome requiring admission to a saudi intensive care unit: A retrospective analysis of 31 cases G. Almekhlafi, Y. Sakr P082 - The ICU response to a hospital outbreak of Middle East respiratory syndrome coronavirus infection H. Al-Dorzi, R. Khan, S. Baharoon, A. Aldawood, A. Matroud, J. Alchin, S. Al Johani, H. Balkhy, Y. Arabi P083 - Middle East respiratory syndrome: Surveillance data analysis S. Alsolamy, S. Y. Yousif, B. O. Alotabi, A. S. Alsaawi P085 - Use of Taqman array card molecular diagnostics in severe pneumonia: A case series J. Ang, MD Curran, D. Enoch, V. Navapurkar, A. Conway Morris P086 - ‘BUNS’: An investigation protocol improves the ICU management of pneumonia R. Sharvill, J. Astin P087 - Pneumonia in patients following secondary peritonitis: epidemiological features and impact on mortality M. Heredia-Rodríguez, E. Gómez-Sánchez, M. T. Peláez-Jareño, E. Gómez-Pesquera, M. Lorenzo-López, P. Liu-Zhu, M. Aragón-Camino, A. Hernández-Lozano, A. Sánchez-López, E. Álvarez-Fuente, E. Tamayo P088 - The use of the “CURB-65 score” by emergency room clinicians in a large teaching hospital J. Patel, C. Kruger P089 - Incidence of community acquired pneumonia with viral infection in mechanically ventilated patients in the medical intensive care unit J. O’Neal, H. Rhodes, J. Jancik P090 - The SAATELLITE Study: Prevention of S aureus Nosocomial Pneumonia (NP) with MEDI4893, a Human Monoclonal Antibody (mAb) Against S aureus B. François, P. F. Laterre, P. Eggimann, A. Torres, M. Sánchez, P. F. Dequin, G. L. Bassi, J. Chastre, H. S. Jafri P091 - Risk factors and microbiological profile for nosocomial infections in trauma patients M. Ben Romdhane, Z. Douira, S. Kamoun, M. Bousselmi, A. Ben Souissi, Y. Boussarsar, A. Riahi, M.S. Mebazaa P092 - Correlation between percentages of ventilated patients developed vap and use of antimicrobial agents in ICU patients. A. Vakalos, V. Avramidis P093 - A comparison of two ventilator associated pneumonia surveillance techniques T. H. Craven, G. Wojcik, K. Kefala, J. McCoubrey, J. Reilly, R. Paterson, D. Inverarity, I. Laurenson, T. S. Walsh P094 - Lung ultrasound before and after fiberbronchoscopy - modifications may improve ventilator-associated pneumonia diagnosis S. Mongodi, B. Bouhemad, A. Orlando, A. Stella, G. Via, G. Iotti, A. Braschi, F. Mojoli P095 - Comparing the accuracy of predictors of mortality in ventilator-associated pneumonia M. Haliloglu, B. Bilgili, U. Kasapoglu, I. Sayan, M. Süzer Aslan, A. Yalcın, I. Cinel P096 - Impact of pRBCs transfusion on percentage of ventilated patients developed VAP in ICU patients A. Vakalos, V. Avramidis P097 - The impact of a series of interventions on the rate of ventilator associated pneumonia in a large teaching hospital H. E. Ellis, K. Bauchmuller, D. Miller, A Temple P098 - The EVADE study: Prevention of Nosocomial Pneumonia (NP) caused by P aeruginosa with MEDI3902, a Novel Bispecific Monoclonal Antibody, against P aeruginosa virulence factors J. Chastre, B. 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Arabi P111 - Does empiric antifungal therapy improve survival in septic critically ill patients? (immunocompromised excluded) A. Trifi, S. Abdellatif, F. Daly, R. Nasri, S. Ben Lakhal P112 - Neurocysticercosis-Qatar experience F. Paramba, N. Purayil, V. Naushad, O. Mohammad, V. Negi, P. Chandra P113 - Early indicators in acute haemorrhagic shock A. Kleinsasser P114 - Filtering of red blood cells reduces the inflammatory response of pulmonary cells in an in vitro model of mechanical ventilation M. R. Witrz, J. F. Buchner-Doeven, A. M. Tuip-de Boer, J. C. Goslings, N. P. Juffermans P115 - Microparticles from red blood cell transfusion induce a pro-coagulant and pro-inflammatory endothelial cell response M. Van Hezel, M. Straat, A Boing, R Van Bruggen, N Juffermans P116 - The contribution of cytokines on thrombosis development during hospitalization in ICU D. Markopoulou, K. Venetsanou, V. Kaldis, D. Koutete, D. Chroni, I. Alamanos P117 - Prophylactic enoxaparin dosing and adjustment through anti-xa monitoring in an inpatient burn unit L. Koch, J. Jancik, H. Rhodes, E. Walter P118 - Determination of optimal cut-off values of haemoglobin, platelet count and fibrinogen at 24 hours after injury associated with mortality in trauma patients K. Maekawa, M. Hayakawa, S. Kushimoto, A. Shiraishi, H. Kato, J. Sasaki, H. Ogura, T. Matauoka, T. Uejima, N. Morimura, H. Ishikura, A. Hagiwara, M. Takeda P119 - Trauma-induced coagulopathy - prothrombin complex concentrate vs fresh frozen plasma O. Tarabrin, S. Shcherbakow, D. Gavrychenko, G. Mazurenko, V. Ivanova, O. Chystikov P120 - First study to prove the superiority of prothrombin complex concentrates on mortality rate over fresh frozen plasma in patients with acute bleeding C. Plourde, J. Lessard, J. Chauny, R. Daoust P121 - Prothrombin complex concentrate vs fresh frozen plasma in obstetric massive bleeding S. Shcherbakow, O. Tarabrin, D. Gavrychenko, G. Mazurenko, O. Chystikov P122 - Impact of FFP transfusion on VAP in ICU patients A. Vakalos, V. Avramidis P123 - Preoperative platelet function test and the thrombin generation assay are predictive for blood loss after cardiac surgery L. Kropman, L. In het Panhuis, J. Konings, D. Huskens, E. Schurgers, M. Roest, B. De Laat, M. Lance P124 - Rotational thromboelastometry versus standard coagulation tests before surgical interventions M. Durila, P. Lukas, M. Astraverkhava, J. Jonas P125 - Correction of impaired clot quality and stability by fibrinogen and activated prothrombin complex concentrate in a model of severe thrombocytopenia I. Budnik, B. Shenkman P126 - Assessment of point-of-care prothrombin time analyzer as a monitor after cardiopulmonary bypass H. Hayami, Y. Koide, T. Goto P127 - Disseminated intravascular coagulation (dic) is underdiagnosed in critically ill patients: do we need d-dimer measurements? R. Iqbal, Y. Alhamdi, N. Venugopal, S. Abrams, C. Downey, C. H. Toh, I. D. 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Sdougka P133 - The implementation of a massive haemorrhage protocol (mhp) for the management of major trauma: a ten year, single-centre study R. Mothukuri, C. Battle, K. Guy, G. Mills, P. Evans P134 - An integrated major haemorrhage protocol for pre-hospital and retrieval medical teams J. Wijesuriya, S. Keogh P135 - The impact of transfusion thresholds on mortality and cardiovascular events in patients with cardiovascular disease (non-cardiac surgery): a systematic review and meta-analysis A. Docherty, R. O’Donnell, S. Brunskill, M. Trivella, C. Doree, L. Holst, M. Parker, M. Gregersen, J. Almeida, T. Walsh, S. Stanworth P136 - The relationship between poor pre-operative immune status and outcome from cardiac surgery is specific to the peri-operative antigenic threat S. Moravcova, J. Mansell, A. Rogers, R. A. Smith, C. Hamilton-Davies P137 - Impact of simple clinical practice guidelines for reducing post-operative atrial fibrillation after cardiac surgery. A. Omar, M. Allam, O. 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Al Khulaifi P142 - Complex evaluation of endothelial dysfunction markers for prognosis of outcomes in patients undergoing cardiac surgery I. Mandel, S. Mikheev, I. Suhodolo, V. Kiselev, Y. Svirko, Y. Podoksenov P143 - New-onset atrial fibrillation in intensive care: incidence, management and outcome S. A. Jenkins, R. Griffin P144 - One single spot measurement of the sublingual microcirculation during acute pulmonary hypertension in a pig model of shock M. S. Tovar Doncel, A. Lima, C. Aldecoa, C. Ince P145 - Assessment of levosimendan as a therapeutic option to recruit the microcirculation in cardiogenic shock – initial experience in cardiac ICU A. Taha, A. Shafie, M. Mostafa, N. Syed, H. Hon P146 - Terlipressin vs. norepinephrine in the Potential Multiorgan Donor(PMD) F. Righetti, E. Colombaroli, G. Castellano P147 - Echocardiography in the potential heart donor exposed to substitution hormonotherapy F. Righetti, E. Colombaroli P148 - Machine learning can reduce rate of monitor alarms M. Hravnak, L. C. Chen, A. D. Dubrawski, G. C. Clermont, M. R. Pinsky P149 - Peripherally inserted central catheters placed in the ICU S. Gonzalez, D. Macias, J. Acosta, P. Jimenez, A. Loza, A. Lesmes, F. Lucena, C. Leon P150 - Recordings of abnormal central venous pressure waveform morphology during an episode of pulmonary hypertension in a porcine shock model M. S. Tovar Doncel, C. Ince, C. Aldecoa, A. Lima P151 - Ultrasound guided central venous access technique among French intensivists M. Bastide, J. Richecoeur, E. Frenoy, C. Lemaire, B. Sauneuf, F. Tamion, S. Nseir, D. Du Cheyron, H. Dupont, J. Maizel P152 - Predictive ability of the Pv-aCO2 gap in patients with shock M. Shaban, R. Kolko, N. Salahuddin, M. Sharshir, M. AbuRageila, A. AlHussain P153 - Comparison of echocardiography and pulmonary artery catheter measurements of hemodynamic parameters in critical ill patients P. Mercado, J. Maizel, L. Kontar, D. Titeca, F. Brazier, A. Riviere, M. Joris, T. Soupison, B. De Cagny, M. Slama P154 - The volume clamp method for noninvasive cardiac output measurement in postoperative cardiothoracic surgery patients: a comparison with intermittent pulmonary artery thermodilution J. Wagner, A. Körner, M. Kubik, S. Kluge, D. Reuter, B. Saugel P155 - Hemodynamic monitoring in patients with septic shock (SS) – CPCCO (continuous pulse contour cardiac output) vs. TEE (transesophageal echocardiography) E. Colombaroli, F. Righetti, G. Castellano P156 - Cardiac output measurement with transthoracic echocardiography in critically ill patients: a pragmatic clinical study T. Tran, D. De Bels, A. Cudia, M. Strachinaru, P. Ghottignies, J. Devriendt, C. Pierrakos P157 - Left ventricular outflow tract velocity time integral correlates with stroke volume index in mechanically ventilated patients Ó. Martínez González, R. Blancas, J. Luján, D. Ballesteros, C. Martínez Díaz, A. Núñez, C. Martín Parra, B. López Matamala, M. Alonso Fernández, M. Chana P158 - Transpulmonary thermodilution (TPTD) derived from femoral vs. jugular central venous catheter: validation of a previously published correction formula and a proprietary correction formula for global end-diastolic volume index (GEDVI) W. Huber, M. Eckmann, F. Elkmann, A. Gruber, I. Klein, R. M. Schmid, T. Lahmer P160 - Dynamic arterial elastance calculated with lidcoplus monitor does not predict changes in arterial pressure after a fluid challenge in postsurgical patients D. Bastoni, H. Aya, L. Toscani, L. Pigozzi, A. Rhodes, M. Cecconi P159 - Venous return driving pressure and resistance in acute blood volume changes P. W. Moller, S. Sondergaard, S. M. Jakob, J. Takala, D. Berger P160 - Dynamic arterial elastance calculated with lidcoplus monitor does not predict changes in arterial pressure after a fluid challenge in postsurgical patients D. Bastoni, H. Aya, L. Toscani, L. Pigozzi, A. Rhodes, M. Cecconi P161 - Analysis of duration of post-operative goal-directed therapy protocol C. Ostrowska, H. Aya, A. Abbas, J. Mellinghoff, C. Ryan, D. Dawson, A. Rhodes, M. Cecconi P162 - Hemodynamic optimization – back to square one? M. Cronhjort, O. Wall, E. Nyberg, R. Zeng, C. Svensen, J. Mårtensson, E. Joelsson-Alm P163 - Effectiveness of fluid thoracic content measurement by bioimpedance guiding intravascular volume optimization in patients with septic shock M. Aguilar Arzapalo, L. Barradas, V. Lopez, M. Cetina P164 - A systematic review on the role of internal jugular vein ultrasound measurements in assessment of volume status in critical shock patients N. Parenti, C. Palazzi, L. A. Amidei, F. B. Borrelli, S. C. Campanale, F. T. Tagliazucchi, G. S. Sedoni, D. L. Lucchesi, E. C. Carella, A. L Luciani P165 - Importance of recognizing dehydration in medical Intensive Care Unit M. Mackovic, N. Maric, M. Bakula P166 - Effect of volume for a fluid challenge in septic patients H. Aya, A. Rhodes, R. M. Grounds, N. Fletcher, M. Cecconi P167 - Fluid bolus practices in a large Australian intensive care unit B. Avard, P. Zhang P168 - Liberal late fluid management is associated with longer ventilation duration and worst outcome in severe trauma patients: a retrospective cohort of 294 patients M. Mezidi, J. Charbit, M. Ould-Chikh, P. Deras, C. Maury, O. Martinez, X. Capdevila P169 - Association of fluids and outcomes in emergency department patients hospitalized with community-acquired pneumonia P. Hou, W. Z. Linde-Zwirble, I. D. Douglas, N. S. Shapiro P170 - Association of positive fluid balance with poor outcome in medicosurgical ICU patients A. Ben Souissi, I. Mezghani, Y. Ben Aicha, S. Kamoun, B. Laribi, B. Jeribi, A. Riahi, M. S. Mebazaa P171 - Impact of fluid balance to organ dysfunction in critically ill patients C. Pereira, R. Marinho, R. Antunes, A. Marinho P172 - Volume bolus in ICU patients: do we need to balance our crystalloids? M. Crivits, M. Raes, J. Decruyenaere, E. Hoste P173 - The use of 6 % HES solution do not reduce total fluid requirement in the therapy of patients with burn shock V. Bagin, V. Rudnov, A. Savitsky, M. Astafyeva, I. Korobko, V. Vein P174 - Electron microscopic assessment of acute kidney injury in septic sheep resuscitated with crystalloids or different colloids T. Kampmeier , P. Arnemann, M. Hessler, A. Wald, K. Bockbreder, A. Morelli, H. Van Aken, S. Rehberg, C. Ertmer P175 - Alterations of conjunctival microcirculation in a sheep model of haemorrhagic shock and resuscitation with 0.9 % saline or balanced tetrastarch P. Arnemann, M. Hessler, T. Kampmeier, S. Rehberg, H. Van Aken, C. Ince, C. Ertmer P176 - A single centre nested pilot study investigating the effect of using 0.9 % saline or Plasma-Lyte 148 ® as crystalloid fluid therapy on gastrointestinal feeding intolerance in mechanically ventilated patients receiving nasogastric enteral nutrition S. Reddy, M. Bailey, R. Beasley, R. Bellomo, D. Mackle, A. Psirides, P. Young P177 - A single centre nested pilot study investigating the effect on post-operative bleeding of using 0.9 % saline or Plasma-Lyte® 148 as crystalloid fluid therapy in adults in ICU after heart surgery S. Reddy, M. Bailey, R. Beasley, R. Bellomo, D. Mackle, P. Young P178 - Extreme hypernatremia and sepsis in a patient with Huntington’s dementia: a conundrum in fluid management H. Venkatesh, S. Ramachandran, A. Basu, H. Nair P179 - Diagnosis and management of severe hypernatraemia in the critical care setting S. Egan, J. Bates P180 - Correlation between arterial blood gas and electrolyte disturbances during hospitalization and outcome in critically ill patients S. Oliveira, N. R. Rangel Neto, F. Q. Reis P181 - Missing the “I” in MUDPILES – a rare cause of high anion gap metabolic acidosis (HAGMA) C. P. Lee, X. L. Lin, C. Choong , K. M. Eu, W. Y. Sim , K. S. Tee, J. Pau , J. Abisheganaden P182 - Plasma NGAL and urinary output: potential parameters for early initiation of renal replacement therapy K. Maas, H. De Geus P183 - Renal replacement therapy for critically ill patients: an intermittent continuity E. Lafuente, R. Marinho, J. Moura, R. Antunes, A. Marinho P184 - A survey of practices related to renal replacement therapy in critically ill patients in the north of England. T. E. Doris, D. Monkhouse, T. Shipley, S. Kardasz, I Gonzalez P185 - High initiation creatinine associated with lower 28-day mortality in critically ill patients necessitating continuous renal replacement therapy S. Stads, A. J. Groeneveld P186 - The impact of Karnofsky performance scale on outcomes in acute kidney injury patients receiving renal replacement therapy on the intensive care unit I. Elsayed, N. Ward, A. Tridente, A. Raithatha P187 - Severe hypophosphatemia during citrate-anticoagulated CRRT A. Steuber, C. Pelletier, S. Schroeder, E. Michael, T. Slowinski, D. Kindgen-Milles P188 - Citrate regional anticoagulation for post dilution continuous renal replacement therapy S. Ghabina P189 - Citrate 18 mmol/l improves anticoagulation during RRT with adsorbing filters F. Turani, A. Belli, S. Busatti, G. Barettin, F. Candidi, F. Gargano, R. Barchetta, M. Falco P190 - Calcium gluconate instead of calcium chloride in citrate-anticoagulated CVVHD O. Demirkiran, M. Kosuk, S. Bozbay P191 - Enhanced clearance of interleukin-6 with continuous veno-venous haemodialysis (CVVHD) using Ultraflux EMiC2 vs. Ultraflux AV1000S V. Weber, J. Hartmann, S. Harm, I. Linsberger, T. Eichhorn, G. Valicek, G. Miestinger, C. Hoermann P192 - Removal of bilirubin with a new adsorbent system: in vitro kinetics S. Faenza, D. Ricci, E. Mancini, C. Gemelli, A. Cuoghi, S. Magnani, M. Atti P193 - Case series of patients with severe sepsis and septic shock treated with a new extracorporeal sorbent T. Laddomada, A. Doronzio, B. Balicco P194 - In vitro adsorption of a broad spectrum of inflammatory mediators with CytoSorb® hemoadsorbent polymer beads M. C. Gruda, P. O’Sullivan, V. P. Dan, T. Guliashvili, A. Scheirer, T. D. Golobish, V. J. Capponi, P. P. Chan P195 - Observations in early vs. late use of cytosorb therapy in critically ill patients K. Kogelmann, M. Drüner, D. Jarczak P196 - Oxiris membrane decreases endotoxin during rrt in septic patients with basal EAA > 0,6 F. Turani, A. B. Belli, S. M. Martni, V. C. Cotticelli, F. Mounajergi, R. Barchetta P197 - An observational prospective study on the onset of augmented renal clearance: the first report S. Morimoto, H. Ishikura P198 - An ultrasound- guided algorithm for the management of oliguria in severe sepsis I. Hussain, N. Salahuddin, A. Nadeem, K. Ghorab, K. Maghrabi P199 - Ultrasound in acute kidney injury (aki). First findings of farius, an education-programme in structural ultrasonography S. K. Kloesel, C. Goldfuss, A. Stieglitz, A. S. Stieglitz, L. Krstevska, G. Albuszies P200 - Effectiveness of renal angina index score predicting acute kidney injury on critically ill patients M. Aguilar Arzapalo, L. Barradas, V. Lopez, A. Escalante, G. Jimmy, M. Cetina P201 - Time length below blood pressure thresholds and progression of acute kidney injury in critically ill patients with or without sepsis: a retrospective, exploratory cohort study J. Izawa, T. Iwami, S. Uchino, M. Takinami, T. Kitamura, T. Kawamura P202 - Anaemia does not affect renal recovery in acute kidney injury J. G. Powell-Tuck, S. Crichton, M. Raimundo, L. Camporota, D. Wyncoll, M. Ostermann P203 - Estimated glomerular filtration rate based on serum creatinine: actual practice in Dutch ICU’s A. Hana, H. R. De Geus P204 - Comparison of estimated glomerular filtration rate calculated by mdrd, ckd-epi-serum-creatinine and ckd-epi-cystatin-c in adult critically ill patients H. R. De Geus, A. Hana P205 - Early diagnosis of septic acute kidney injury in medical critical care patients with a urine cell cycle arrest marker: insulin like growth factor binding protein-7 (IGFBP-7) M. Aydogdu, N. Boyaci, S. Yuksel, G. Gursel, A. B. Cayci Sivri P206 - Urinary neutrophil gelatinase-associated lipocalin as early biomarker of severe acute kidney injury in intensive care J. Meza-Márquez, J. Nava-López, R. Carrillo-Esper P207 - Shrunken pore syndrome is associated with a sharp rise in mortality in patients undergoing elective coronary artery bypass grafting A. Dardashti, A. Grubb P208 - The biomarker nephrocheck™ can discriminate the septic shock patients with an akin 1 or 2 acute renal failure who will not progress toward the akin 3 level J. Maizel, M. Wetzstein, D. Titeca, L. Kontar, F. Brazier, B. De Cagny, A. Riviere, T. Soupison, M. Joris, M. Slama P209 - A worldwide multicentre evaluation of acute kidney injury in septic and non-septic critically ill patients: the intensive care over nations (icon) audit E. Peters, H. Njimi, P. Pickkers, J. L. Vincent P210 - Does enhanced recovery after surgery reduce the incidence of acute kidney injury in those undergoing major gynae-oncological surgery? M. Waraich , J. Doyle, T. Samuels, L. Forni P211 - Identification of risk factors for the development of acute kidney injury after lower limb arthroplasty N. Desai, R. Baumber, P. Gunning, A. Sell P212 - Incidences and associations of acute kidney injury after major trauma S. Lin, H. Torrence, M. O’Dwyer, C. Kirwan, J. Prowle P213 - Acute kidney injury of major trauma patients T Kim P214 - Trajectory of serum creatinine after major surgery and the diagnosis of acute kidney injury M. E. O’Connor, R. W. Hewson, C. J. Kirwan, R. M. Pearse, J. Prowle P215 - Epidemiology of acute kidney injury after cardiac surgery. A single center retrospective study S. Hanoura , A. Omar, H. Othamn, S. Sudarsanan , M. Allam, M. Maksoud, R. Singh, A. Al Khulaifi P216 - Post-operative acute kidney injury after major non-cardiac surgery and its association with death in the following year M. E. O’Connor, R. W. Hewson, C. J. Kirwan, R. M. Pearse, J. Prowle P217 - Factors affecting acute renal failure in intensive care unit and effect of these factors on mortality O. Uzundere, D. Memis , M. Ýnal, A. , N. Turan P218 - Results of the live kidney transplantations according to national data of turkish organ and tissue information system M. A. Aydin, H. Basar, I. Sencan, A. Kapuagasi, M. Ozturk, Z. Uzundurukan, D. Gokmen, A. Ozcan, C. Kaymak P219 - Anaesthesia procedure and intensive therapy in patients with neck phlegmon V. A. Artemenko, A. Budnyuk P220 - Nasal high flow oygen for acute respiratory failure: a systematic review R. Pugh , S. Bhandari P221 - Setting optimal flow rate during high flow nasal cannula support: preliminary results T. Mauri, C. Turrini, T. Langer, P. Taccone, C. A. Volta, C. Marenghi, L. Gattinoni, A. Pesenti P222 - Dose to dose consistency across two different gas flow rates using cystic fibrosis and normal adult breathing profiles during nasal high flow oxygen therapy L. Sweeney, A . O’ Sullivan, P. Kelly, E. Mukeria, R. MacLoughlin P223 - Final results of an evaluation of airway medix closed suction system compared to a standard closed suction system M. Pfeffer, J. T. Thomas, G. B. Bregman, G. K. Karp, E. K. Kishinevsky, D. S. Stavi, N. A. Adi P224 - Different cuff materials and different leak tests - one size does not fit all T. Poropat, R. Knafelj P225 - Observational study on the value of the cuff-leak test and the onset of upper airway obstruction after extubation E. Llopart, M. Batlle, C. De Haro, J. Mesquida, A. Artigas P226 - A device for emergency transtracheal lung ventilation D. Pavlovic, L. Lewerentz, A. Spassov, R. Schneider P227 - Long-term outcome and health-related quality of life in patients discharged from the intensive care unit with a tracheostomy and with or without prolonged mechanical ventilation S. De Smet, S. De Raedt, E. Derom, P Depuydt, S. Oeyen, D. Benoit, J. Decruyenaere P228 - Ultrasound-guided percutaneous dilational tracheostomy versus bronchoscopy-guided percutaneous dilational tracheostomy in critically ill patients (trachus): a randomized clinical trial A. Gobatto, B. Bese, P. Tierno, L. Melro, P. Mendes, F. Cadamuro, M. Park, L. M. Malbouisson P229 - Is it safe to discharge patients with tracheostomy from the ICU to the ward? B. C. Civanto, J. L. Lopez, A. Robles, J. Figueira, S. Yus, A. Garcia P230 - The application of tracheostomy in children in ICU A. Oglinda, G. Ciobanu, C. Oglinda, L. Schirca, T. Sertinean, V. Lupu P231 - The impact of passive humidifiers on aerosol drug delivery during mechanical ventilation P. Kelly, A. O’Sullivan, L. Sweeney, R. MacLoughlin P232 - Evaluation of vibrating mesh and jet nebuliser performance at two different attachment setups in line with a humidifier nebuliser system A. O’Sullivan, P. Kelly, L. Sweeney, E. Mukeria, M. Wolny , R. MacLoughlin P233 - Psv-niv versus cpap in the treatment of acute cardiogenic pulmonary edema A. Pagano, F. Numis, G. Vison, L. Saldamarco, T. Russo, G. Porta, F. Paladino P234 - Noninvasive ventilation in patients with haematologic malignancy: a retrospective review C. Bell, J. Liu, J. Debacker, C. Lee, E. Tamberg, V. Campbell, S. Mehta P235 - Use of non-invasive ventilation in infectious diseases besides classical indications A. Silva-Pinto, A. Sarmento, L. Santos P236 - The impact of fragility on noninvasive mechanical ventilation application and results in the ICU Ý. Kara, F. Yýldýrým, A. Zerman, Z. Güllü, N. Boyacý, B. Basarýk Aydogan, Ü. Gaygýsýz, K. Gönderen, G. Arýk, M. Turkoglu, M. Aydogdu, G. Aygencel, Z. Ülger, G. Gursel P237 - Effects of metabolic alkalosis on noninvasive ventilation success and ICU outcome in patients with hypercapnic respiratory failure N. Boyacý, Z. Isýkdogan, Ö. Özdedeoglu, Z. Güllü, M. Badoglu, U. Gaygýsýz, M. Aydogdu, G. Gursel P238 - Asynchrony index and breathing patterns of acute exacerbation copd patients assisted with noninvasive pressure support ventilation and neurally adjusted ventilatory assist N. Kongpolprom, C. Sittipunt P239 - High frequency jet ventilation for severe acute hypoxemia A. Eden, Y. Kokhanovsky, S. Bursztein – De Myttenaere, R. Pizov P240 - HFOV revisited: a 7 year retrospective analysis of patients receiving HFOV who met oscillate trial entry criteria L. Neilans, N. MacIntyre P241 - Implementation of a goal-directed mechanical ventilation order set driven by respiratory therapists can improve compliance with best practices for mechanical ventilation M. Radosevich, B. Wanta, V. Weber, T. Meyer, N. Smischney, D. Brown, D. Diedrich P242 - A reduction in tidal volumes for ventilated patients on ICU calculated from IBW. can it minimise mortality in comparison to traditional strategies? A . Fuller, P. McLindon, K. Sim P243 - Predictive value of lung aeration scoring using lung ultrasound in weaning failure M. Shoaeir, K. Noeam, A. Mahrous, R. Matsa, A. Ali P244 - Conventional versus automated weaning from mechanical ventilation using SmartCare™ C. Dridi, S. Koubaji, S. Kamoun, F. Haddad, A. Ben Souissi, B. Laribi, A. Riahi, M. S. Mebazaa P245 - Ultrasonographic evaluation protocol for weaning from mechanichal ventilation A. Pérez-Calatayud, R. Carrillo-Esper, A. Zepeda-Mendoza, M. Diaz-Carrillo, E. Arch-Tirado P246 - Diaphragm ultrasonography: a method for weaning patients from mechanical ventilation S. Carbognin, L. Pelacani, F. Zannoni, A. Agnoli, G. Gagliardi P247 - Dorsal diaphragmatic excursion tracks transpulmonary pressure in ventilated ARDS patients: a potential non-invasive indicator of lung recruitment? R. Cho, A. Adams , S. Lunos, S. Ambur, R. Shapiro, M. Prekker P248 - Pulse oximetry in the icu patient: is the perfusion index of any value? M. Thijssen, L. Janssen, N. Foudraine P249 - Ventilation is a better assessment of respiratory status than EtCO2 C. J. Voscopoulos, J. Freeman P250 - Evaluation of the relationship between non-invasive minute ventilation and end-tidal CO2 in patients undergoing general vs spinal anesthesia C. J. Voscopoulos, J. Freeman, E. George P251 - Respiratory volume monitoring provides early warning of respiratory depression and can be used to reduce false alarms in non-intubated patients C. J. Voscopoulos, D. Eversole, J. Freeman, E. George P252 - P/i index: a predictive edi-derived weaning index during nava S. Muttini, R. Bigi, G. Villani, N. Patroniti P253 - Adequacy of ventilation in patients receiving opioids in the post anesthesia care unit: minute ventilation versus respiratory rate G. Williams, C. J. Voscopoulos, J. Freeman, E. George P254 - Comparison of regional and global expiratory time constants measured by electrical impedance tomography (EIT) A. Waldmann, S. Böhm, W. Windisch, S. Strassmann, C. Karagiannidis P255 - Electrical impedance tomography: robustness of a new pixel wise regional expiratory time constant calculation A. Waldmann, S. Böhm, W. Windisch, S. Strassmann, C. Karagiannidis P256 - Validation of regional and global expiratory time constant measurement by electrical impedance tomography in ards and obstructive pulmonary diseases C. K. Karagiannidis, A. W. Waldmann, S. B. Böhm, S. Strassmann, W. W. Windisch P257 - Transpulmonary pressure in a model with elastic recoiling lung and expanding chest wall P. Persson, S. Lundin, O. Stenqvist P258 - Lactate in pleural and abdominal effusion G. Porta, F. Numis, C. S. Serra, A. P. Pagano, M. M. Masarone, L. R. Rinaldi, A. A. Amelia, M. F. Fascione, L. A. Adinolfi, E. R. Ruggiero P259 - Outcome of patients admitted to the intensive care with pulmonary fibrosis F. Asota, K. O’Rourke, S. Ranjan, P. Morgan P260 - Sedation and analgesia practice in extra-corporeal membrane oxygenation (ECMO)-treated patients with acute respiratory distress syndrome (ARDS): a retrospective study J. W. DeBacker, E. Tamberg, L. O’Neill, L. Munshi, L. Burry, E. Fan, S. Mehta P261 - Characteristics and outcomes of patients deemed not eligible when referred for veno-venous extracorporeal membrane oxygenation (vv-ECMO) S. Poo, K. Mahendran, J. Fowles, C. Gerrard, A. Vuylsteke P262 - The SAVE SMR for veno-arterial ECMO R. Loveridge, C. Chaddock, S. Patel, V. Kakar, C. Willars, T. Hurst, C. Park, T. Best, A. Vercueil, G. Auzinger P263 - A simplified score to predict early (48 h) mortality in patients being considered for VA-ECMO A. Borgman, A. G. Proudfoot, E. Grins, K. E. Emiley, J. Schuitema, S. J. Fitch, G. Marco, J. Sturgill, M. G. Dickinson, M. Strueber, A. Khaghani, P. Wilton, S. M. Jovinge P264 - Lung function six months post extra corporeal membrane oxygenation (ECMO) for severe acute respiratory failure in adult survivors C. Sampson, S. Harris-Fox P265 - Bicarbonate dialysis removes carbon dioxide in hypoventilated rodents. M. E. Cove, L. H. Vu, A. Sen, W. J. Federspiel, J. A. Kellum P266 - Procalcitonin as predictor of primary graft dysfunction and mortality in post-lung transplantation C. Mazo Torre, J. Riera, S. Ramirez, B. Borgatta, L. Lagunes, J. Rello P267 - New molecular biomarkers of acute respiratory distress syndrome in abdominal sepsis A. K. Kuzovlev, V. Moroz, A. Goloubev, S. Polovnikov, S. Nenchuk P268 - Tight junction’s proteins claudin -5 and regulation by tnf in experimental murine lung injury model of ali/ards V. Karavana, C. Glynos, A. Asimakos, K. Pappas, C. Vrettou, M. Magkou, E. Ischaki, G. Stathopoulos, S. Zakynthinos P269 - Cell counts in endobronchial aspirate to assess airway inflammation in ARDS patients: a pilot study S. Spadaro, I. Kozhevnikova, F. Dalla Corte, S. Grasso, P. Casolari, G. Caramori, C. Volta P270 - Epidemiological and clinical profile of patients with acute respiratory distress syndrome in the surgical intensive care unit surgical, hospital JRA, Antananarivo T. Andrianjafiarinoa, T. Randriamandrato, T. Rajaonera P271 - Effect of high PEEP after recruitment maneuver on right ventricular function in ARDS. Is it good for the lung and for the heart? S. El-Dash, ELV Costa, MR Tucci, F Leleu, L Kontar, B. De Cagny, F. Brazier, D. Titeca, G. Bacari-Risal, J. Maizel, M. Amato, M. Slama P272 - Effect of recruitment maneuver on left ventricular systolic strain P. Mercado, J. Maizel, L. Kontar, D. Titeca, F. Brazier, A. Riviere, M. Joris, T. Soupison, B. De Cagny, S. El Dash, M. Slama P273 - Inhaled nitric oxide – is switching supplier cost effective? Remmington, A. Fischer, S. Squire, M. Boichat P274 - Epidemiological study of severe acute pancreatitis in Japan, comparison of the etiology and the patient outcomes on 1159 patients. H. Honzawa, H. Yasuda, T. Adati, S. Suzaki, M. Horibe, M. Sasaki, M. Sanui P275 - Extracorporeal liver support therapy. Experience in an intensive care unit R. Marinho, J. Daniel, H. Miranda, A. Marinho P276 - Accuracy of mortality prediction models in acute versus acute-on-chronic liver failure in the intensive care setting K. Milinis, M. Cooper, G. R. Williams, E. McCarron, S. Simants, I. Patanwala, I. Welters P277 - Risk of coronary artery disease in patients with chronic liver disease: a population based cohort study Y. Su P278 - 20 years of liver transplantation in Santiago de Compostela (Spain). Experience review J. Fernández Villanueva, R. Fernández Garda, A. López Lago, E. Rodríguez Ruíz, R. Hernández Vaquero, S. Tomé Martínez de Rituerto, E. Varo Pérez P279 - Diarrhea is a risk factor for liver injury and may lead to intestinal failure associated liver disease in critical illness N. Lefel, F. Schaap, D. Bergmans, S. Olde Damink, M. Van de Poll P280 - Bowel care on the intensive care unit: constipation guideline compliance and complications K. Tizard, C. Lister, L. Poole P281 - Malnutrition assessed by phase angle determines outcomes in low risk cardiac surgery patients D. Ringaitiene, D. Gineityte, V. Vicka, I. Norkiene, J. Sipylaite P282 - Preoperative fasting times in an irish hospital A. O’Loughlin, V. Maraj, J. Dowling P283 - Costs and final outcome of early x delayed feeding in a private Brazil ICU M. B. Velasco, D. M. Dalcomune, E. B. Dias, S. L. Fernandes P284 - Can ventilator derived energy expenditure measurements replace indirect calorimetry? T. Oshima, S. Graf, C. Heidegger, L. Genton, V. Karsegard, Y. Dupertuis, C. Pichard P285 - Revisiting the refeeding syndrome: results of a systematic review N. Friedli, Z. Stanga, B. Mueller, P. Schuetz P286 - Compliance with the new protocol for parenteral nutrition in our ICU L. Vandersteen, B. Stessel, S. Evers, A. Van Assche, L. Jamaer, J. Dubois P287 - Nutrition may be another treatment in the intensive care unit where less is more? R. Marinho, H. Castro, J. Moura, J. Valente, P. Martins, P. Casteloes, C. Magalhaes, S. Cabral, M. Santos, B. Oliveira, A. Salgueiro, A. Marinho P288 - Should we provide more protein to critically ill patients? R. Marinho, M. Santos, E. Lafuente, H. Castro, S. Cabral, J. Moura, P. Martins, B. Oliveira, A. Salgueiro, S. Duarte, S. Castro, M. Melo, P. Casteloes, A. Marinho P289 Protein provision in an adult intensive care unit S. Gray P290 - Prevalence and clinical outcomes of vitamin d deficiency in the medical critically ill patients in Songklanagarind hospital K. Maipang, R. Bhurayanontachai P291 - Vitamin d deficiency strongly predicts adverse medical outcome across different medical inpatient populations: results from a prospective study L. G. Grädel, P. Schütz P292 - Omega-3 fatty acids in patients undergoing cardiac surgery: a systematic review and meta-analysis P. Langlois, W. Manzanares P293 - Can 5-hydroxytriptophan prevent post-traumatic stress disorder in critically ill patients? R. Tincu, C. Cobilinschi, D. Tomescu, Z. Ghiorghiu, R. Macovei P294 - Parenteral selenium in the critically ill: an updated systematic review and meta-analysis W. Manzanares, P. Langlois, M. Lemieux, G. Elke, F. Bloos, K. Reinhart, D. Heyland P295 - Probiotics in the critically ill: an updated systematic review and meta-analysis P. Langlois, M. Lemieux, I. Aramendi, D. Heyland, W. Manzanares P296 - Diabetes with hyperglycemic crisis episodes may be associated with higher risk of pancreatic cancer: a population-based cohort study Y. Su P297 - Incidence of hypoglycemia in an intensive care unit depending on insulin protocol R. Marinho, N. Babo, A. Marinho P298 - Severity of the diseases is two-dimensionally correlated to blood glucose, including blood glucose variability, especially in moderately to severely ill patients with glucose intolerance. M. Hoshino, Y. Haraguchi, S. Kajiwara, T. Mitsuhashi, T. Tsubata, M. Aida P299 - A study of glycemic control by subcutaneous glargine injection transition from continuous regular insulin infusion in critically ill patients T. Rattanapraphat, R. Bhurayanontachai, C. Kongkamol, B. Khwannimit P300 - Glycemic control in Portuguese intensive care unit R. Marinho, M. Santos, H. Castro, E. Lafuente, A. Salgueiro, S. Cabral, P. Martins, J. Moura, B. Oliveira, M. Melo, B. Xavier, J. Valente, C. Magalhaes, P. Casteloes, A. Marinho P301 - Impact of hyperglycemia duration on the day of operation on short-term outcome of cardiac surgery patients D. Moisidou, F. Ampatzidou, C. Koutsogiannidis, M. Moschopoulou, G. Drossos P302 - Lactate levels in diabetic ketoacidosis patients at ICU admissions G. Taskin, M. Çakir, AK Güler, A. Taskin, N. Öcal, S. Özer, L. Yamanel P303 - Intensive care implications of merging heart attack centre units in London J. M. Wong, C. Fitton, S. Anwar, S. Stacey P304 - Special characteristics of in-hospital cardiac arrests M. Aggou, B. Fyntanidou, S. Patsatzakis, E. Oloktsidou, K. Lolakos, E. Papapostolou, V. Grosomanidis P305 - Clinical evaluation of ICU-admitted patients who were resuscitated in the general medicine ward S. Suda , T. Ikeda, S. Ono, T. Ueno, Y. Izutani P306 - Serious game evaluation of a one-hour training basic life support session for secondary school students: new tools for future bystanders S. Gaudry, V. Desailly, P. Pasquier, PB Brun, AT Tesnieres, JD Ricard, D. Dreyfuss, A. Mignon P307 - Public and clinical staff perceptions and knowledge of CPR compared to local and national data J. C White, A. Molokhia, A. Dean, A. Stilwell, G. Friedlaender P308 Dispatcher-assisted telephone cardiopulmonary resuscitation using a French-language compression-ventilation pediatric protocol M. Peters, S. Stipulante, A. Delfosse, AF Donneau, A. Ghuysen P309 Dantrolene versus amiodarone for resuscitation – an experimental study C. Feldmann, D. Freitag, W. Dersch, M. Irqsusi, D. Eschbach, T. Steinfeldt, H. Wulf, T. Wiesmann P310 Long term survival and functional neurological outcome in comatose survivors undergoing therapeutic hypothermia N. Kongpolprom, J. Cholkraisuwat P311 Impact of kidney disease on mortality and neurological outcome in out-of-hospital cardiac arrest: a prospective observational study S. Beitland , E. Nakstad, H. Stær-Jensen , T. Drægni , G. Andersen , D. Jacobsen , C. Brunborg, B. Waldum-Grevbo , K. Sunde P312 ICU dependency of patients admitted after primary percutaneous coronary intervention (PPCI) following out of the hospital cardiac arrest K. Hoyland, D. Pandit P313 Prognostic indicators and outcome prediction model for patients with return of spontaneous circulation from cardiopulmonary arrest: comprehensive registry of in-hospital intensive care on OHCA survival (critical) study in Osaka, Japan K. Hayakawa P314 Cerebral oxygen saturation during resuscitation in a porcine model of cardiac arrest E. Oloktsidou, K. Kotzampassi, B. Fyntanidou, S. Patsatzakis, L. Loukipoudi, E. Doumaki, V. Grosomanidis P315 Presumption of cardiopulmonary resuscitation for sustaining cerebral oxidation using regional cerebral saturation of oxygen: observational cohort study (press study) H. Yasuda P316 EEG reactivity in patients after cardiac arrest: a close look at stimuli MM Admiraal, M. Van Assen, MJ Van Putten, M. Tjepkema-Cloostermans, AF Van Rootselaar, J. Horn P317 Prognostic value of neuron-specific enolase after cardiac arrest F. Ragusa, A. Marudi , S. Baroni, A. Gaspari, E. Bertellini P318 Correlation between electroencephalographic findings and serum neuron specific enolase with outcome of post cardiac arrest patients A. Taha, T. Abdullah, S. Abdel Monem P319 Introduction of a targeted temperature management strategy following cardiac arrest in a district general hospital intensive care unit. S. Alcorn, S. McNeill, S. Russell P320 The evolution of cerebral oxygen saturation in post-cardiac arrest patients treated with therapeutic hypothermia W. Eertmans, C. Genbrugge, I. Meex, J. Dens, F. Jans, C. De Deyne P321 Prognostic factors and neurological outcomes of therapeutic hypothermia in comatose survivors from cardiac arrest: 8-year single center experience J. Cholkraisuwat, N. Kongpolprom P322 Adherence to targeted temperature management after out of hospital cardiac arrest B. Avard, R. Burns P323 Implementation of a therapeutic hypothermia protocol for comatose survivors of out-of-hospital cardiac arrest. A. Patarchi, T. Spina P324 Factors associated with ventilator weaning after targeted temperature management for cardiac arrest patients in japan H. Tanaka, N. Otani, S. Ode, S. Ishimatsu P325 Differential activation of c-fos in paraventricular nuclei of the hypothalamus and thalamus of the rat following myocardial infarction J. Cho, J. B. Moon, C. W. Park, T. G. Ohk, M. C. Shin, M. H. Won P326 Monitoring of cTroponin I in patients with acute ischemic stroke - predictor of inhospital mortality S. Dakova, Z. Ramsheva, K. Ramshev P327 Hyperthermic preconditioning severely accelerates neuronal damage in the gerbil ischemic hippocampal dentate gyrus via decreasing sods expressions J. Cho, J. B. Moon, C. W. Park, T. G. Ohk, M. C. Shin P328 Failure in neuroprotection of remote limb ischemic post conditioning in the hippocampus of a gerbil model of transient cerebral ischemia J. Cho, J. B. Moon, C. W. Park, T. G. Ohk, M. C. Shin P329 Brain death and admission diagnosis in neurologic intensive care unit, a correlation? A Marudi, S Baroni, A Gaspari, E Bertellini P330 Brain magnetic resonance imaging findings in patients with septic shock G. Orhun, E. Senturk, P. E. Ozcan, S. Sencer, C. Ulusoy, E. Tuzun, F . Esen P331 Benefits of L-carnitine in valproic acid induced encephalopathy R. Tincu, C. Cobilinschi, D. Tomescu, Z. Ghiorghiu, R. Macovei P332Automatic analysis of EEG reactivity in comatose patients M. Van Assen, M. M. Admiraal, M. J. Van Putten, M. Tjepkema-Cloostermans, A. F. Van Rootselaar, J. Horn P333 Usefulness of common ICU severity scoring systems in predicting outcome after spontaneous intracerebral hemorrhage M. Fallenius, M. B. Skrifvars, M. Reinikainen, S. Bendel, R. Raj P334 Evalution of patients with suspected subarachnoid haemorrhage and negative ct imaging M. Abu-Habsa, C. Hymers, A. Borowska, H. Sivadhas, S. Sahiba, S. Perkins P335 Timing of endovascular and surgical treatment for aneurysmal subarachnoid haemorrhage: early but not so fast. J. Rubio, J. A. Rubio, R. Sierra P336 Red blood cell transfusion in aneurysmal subarachnoid hemorrhage – the Sahara cohort study S. English, M. Chasse, A. Turgeon, F. Lauzier, D. Griesdale, A. Garland, D. Fergusson, R. Zarychanski, A. Tinmouth, C. Van Walraven, K. Montroy, J. Ziegler, R. Dupont Chouinard, R. Carignan, A. Dhaliwal, C. Lum, J. Sinclair, G. Pagliarello, L. McIntyre P337 - Aneurysmal subarachnoid hemorrhage and anemia: a canadian multi-centre retrospective cohort study S. English, M. Chasse, A. Turgeon, F. Lauzier, D. Griesdale, A. Garland, D. Fergusson, R. Zarychanski, A. Tinmouth, C. Van Walraven, K. Montroy, J. Ziegler, R. Dupont Chouinard, R. Carignan, A. Dhaliwal, C. Lum, J. Sinclair, G. Pagliarello, L. McIntyre P338 - Does the neutrophil-to-lymphocyte (NLR) ratio predict symptomatic vasospasm or delayed cerebral ischemia (DCI) after aneurysmal subarachnoid haemorrhage (SAH)? T. Groza, N. Moreau, D. Castanares-Zapatero, P. Hantson P339 - ICU-acquired infections in aneurysmal subarachnoid hemorrhage patients: impact on ICU and hospital length of stay M. Carbonara , F. Ortolano, T. Zoerle, S. Magnoni, S. Pifferi, V. Conte, N. Stocchetti P340 - Cerebral metabolic effects of normobaric hyperoxia during the acute phase of aneurysmal subarachnoid hemorrhage L. Carteron, T. Suys, C. Patet, H. Quintard, M. Oddo P341 - Postoperative care for elective craniotomy: where is best done? J. A. Rubio, J. Rubio, R. Sierra P342 - 5-year follow-up of patients after transplantation of organs from donors from neurocritical care V. Spatenkova, E. Pokorna, P. Suchomel P343 - Evaluation of levetiracetam pharmacokinetics after severe traumatic brain injury in neurocritical care patients at a level one trauma center N. Ebert, J. Jancik, H. Rhodes P344 - Model based time series cluster analysis to determine unique patient states in traumatic brain injury T. Bylinski, C. Hawthorne, M. Shaw, I. Piper, J. Kinsella P345 - Brain compartment monitoring capabilities from ICP to BI (bioimpedance) during HS (hypertonic saline) administration. State of art simulation outcome depending on brain swelling type A. K. Kink , I. R. Rätsep P346 - Transfusion of red blood cells in patients with traumatic brain injury admitted to Canadian trauma health centers: a multicenter cohort study A. Boutin, L. Moore, M. Chasse, R. Zarychanski, F. Lauzier, S. English, L. McIntyre, J. Lacroix, D. Griesdale, P. Lessard-Bonaventure, A. F. Turgeon P347 - Hemoglobin thresholds and red blood cell transfusions in adult patients with moderate or severe traumatic brain injury: a retrospective cohort study A. Boutin, L. Moore, R. Green, P. Lessard-Bonaventure, M. Erdogan, M. Butler, F. Lauzier, M. Chasse, S. English, L. McIntyre, R. Zarychanski, J. Lacroix, D. Griesdale, P. Desjardins, D. A. Fergusson, A. F. Turgeon P348 - Characteristics of patients with gunshot wounds to the head - an observational Brazilian study B. Goncalves, B. Vidal, C. Valdez, A. C. Rodrigues, L. Miguez, G. Moralez P349 - Base excess as predictor for ICU admission and the injury severity in blunt trauma patients T. Hong P350 - Enhancement of usual emergency department care with proadrenomedullin to improve outcome prediction - Results from the multi-national, prospective, observational TRIAGE study A. Kutz, P. Hausfater, D. Amin, T. Struja, S. Haubitz, A. Huber, B. Mueller, P. Schuetz P351 - Developing an innovative emergency medicine point-of-care simulation programme T. Brown, J. Collinson, C. Pritchett, T. Slade P352 - The InSim program: an in situ simulation program for junior trainees in intensive care M. Le Guen, S. Hellings, R. Ramsaran P353 - Impact of excessive and inappropriate troponin testing in the emergency setting how good are we A. Alsheikhly P354 - The development of time tracking monitor at emergency department T. Abe P355 - Role of focussed echocardiography in emergency assessment of syncope L. Kanapeckaite, M. Abu-Habsa, R. Bahl P356 - Insertion of an open-ended 14-gauge catheter through the chest wall causes a significant pneumothorax in a self-ventilating swine model M. Q Russell, K. J. Real, M. Abu-Habsa , R. M. Lyon, N. P. Oveland P357 - Ez-io® intraosseous access teaching in the workplace using a mobile ‘tea trolley’ training method J. Penketh, M. Mcdonald, F. Kelly P358 - Black widow envenomation in Saudi Arabia: a prospective observational case series M. Alfafi, S. Alsolamy, W. Almutairi, B. Alotaibi P359 - Mechanical ventilation in patients with overdose not yet intubated on icu admission A. E. Van den Berg, Y. Schriel, L. Dawson, I. A. Meynaar P360 - Central nervous system depressants poisoning and ventilator associated pneumonia: an underrated risk factor in toxicological intensive care unit H. Talaie P361 - Acute barium intoxication treated with hemodiafiltration D. Silva, S. Fernandes, J. Gouveia, J. Santos Silva P362 - Major trauma presenting to the emergency department. the spectrum of cycling injuries in Ireland J. Foley, A. Kaskovagheorgescu, D. Evoy, J. Cronin, J. Ryan P363 - Burns from French military operations: a 14-year retrospective observational analysis. M. Huck, C. Hoffmann, J. Renner, P. Laitselart, N. Donat, A. Cirodde, J. V. Schaal, Y. Masson, A. Nau, T. Leclerc P364 - A comparison of mortality scores in burns patients on the intensive care unit. O. Howarth, K. Davenport, P. AD - University of Western Ontario, London, Canada. ISNI: 0000 0004 1936 8884. GRID: grid.39381.30 Hospital Dr Negrín, Las Palmas de GC, Spain Hospital San Jorge, Huesca, Spain. ISNI: 0000 0004 1765 5935. GRID: grid.415076.1 Hospital Universitari del Mar, Barcelona, Spain. ISNI: 0000 0004 1767 8811. GRID: grid.411142.3 Hospital Universitario de la Princesa, Madrid, Spain. ISNI: 0000 0004 1767 647X. GRID: grid.411251.2 Hospital Clínico y Universitario de Valencia, Valencia, Spain. GRID: grid.411308.f Hospital Universitari Son Espases, Palma de Mallorca, Spain. ISNI: 0000 0004 1796 5984. GRID: grid.411164.7 Medical Faculty of Istanbul, Istanbul University, Anesthesiology and Intensive Care, Istanbul, Turkey. ISNI: 0000 0001 2166 6619. GRID: grid.9601.e Medical Faculty of Istanbul, Physiology, Istanbul University, Istanbul, Turkey. ISNI: 0000 0001 2166 6619. GRID: grid.9601.e Institute of Experimental Medicine, Istanbul University, Neuroscience, Istanbul, Turkey. ISNI: 0000 0001 2166 6619. GRID: grid.9601.e Medical Faculty of Istanbul, Forensic Medicine, Istanbul University, Istanbul, Turkey. ISNI: 0000 0001 2166 6619. GRID: grid.9601.e Institute of Experimental Medicine, Immunology, Istanbul University, Istanbul, Turkey. ISNI: 0000 0001 2166 6619. GRID: grid.9601.e Ben-Gurion University of the Negev, Beer-Sheva, Israel. ISNI: 0000 0004 1937 0511. GRID: grid.7489.2 Soroka Medical Center, Beer-Sheva, Israel. ISNI: 0000 0004 0470 8989. GRID: grid.412686.f Osaka University Graduate School of Medicine, Suita, Japan. ISNI: 0000 0004 0373 3971. GRID: grid.136593.b Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan. ISNI: 0000 0000 8902 2273. GRID: grid.174567.6 Tokyo Medical University Hachioji Medical Center, Hachioji, Tokyo Japan. GRID: grid.411909.4 National Defense Medical College, Tokorozawa, Saitama Japan. ISNI: 0000 0004 0374 0880. GRID: grid.416614.0 Hachiouji medical center, Tokyo medical university, Tokyo, Japan. ISNI: 0000 0001 0663 3325. GRID: grid.410793.8 Kanazawa University, Kanazawa, Japan. ISNI: 0000 0001 2308 3329. GRID: grid.9707.9 Kanazawa University Hospital, Kanazawa, Japan. ISNI: 0000 0004 0615 9100. GRID: grid.412002.5 ThermoFisher, Hennigsdorf, Germany Institut für Klinische Chemie und Laboratoriumsmedizin, Mainz, Germany MVZ Labor Limbach Gruppe, Berlin, Germany Kantonsspital Aarau, Aarau, Switzerland. ISNI: 0000 0000 8704 3732. GRID: grid.413357.7 King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia. ISNI: 0000 0001 2191 4301. GRID: grid.415310.2 Saint Savvas Hospital, Athens, Greece. GRID: grid.416564.4 Tokyo Medical University, Tokyo, Japan. ISNI: 0000 0001 0663 3325. GRID: grid.410793.8 Tokyo Medical University, Hachioji Medical Center, Tokyo, Japan. GRID: grid.411909.4 Hospital Virgen de la Victoria, Málaga, Spain. ISNI: 0000 0000 9788 2492. GRID: grid.411062.0 St Helens and Knowsley NHS Trust, Merseyside, UK Maastricht University, Maastricht, Netherlands. ISNI: 0000 0001 0481 6099. GRID: grid.5012.6 Center for Experimental and Molecular medicine, Amsterdam, Netherlands Academic Medical Center, Amsterdam, Netherlands. ISNI: 0000000404654431. GRID: grid.5650.6 NISCHR Haemostasis Biomarker Research Unit, Swansea, UK Hôpital Lariboisière, Paris, France. ISNI: 0000 0000 9725 279X. GRID: grid.411296.9 Sphingotec, Berlin, Germany Hôpital Cochin, Paris, France. ISNI: 0000 0001 0274 3893. GRID: grid.411784.f Hôpital Saint-Antoine, Paris, France. ISNI: 0000 0004 1937 1100. GRID: grid.412370.3 CHRU de Montpellier, Montpellier, France. ISNI: 0000 0000 9961 060X. GRID: grid.157868.5 Hôpital Saint-Louis, Paris, France. ISNI: 0000 0001 2300 6614. GRID: grid.413328.f AP-HM, Marseille, France. ISNI: 0000 0001 0407 1584. GRID: grid.414336.7 Hôpital Ambroise Paré, Paris, France. ISNI: 0000 0000 9982 5352. GRID: grid.413756.2 Christiana Care Health System, Newark, USA. ISNI: 0000 0004 0444 1241. GRID: grid.414316.5 Skane University Hospital, Lund University, Lund, Sweden. ISNI: 0000 0001 0930 2361. GRID: grid.4514.4 Carol Davila University of Medicine and Pharmacy, Bucharest, Romania. ISNI: 0000 0000 9828 7548. GRID: grid.8194.4 Hadassah-Hebrew University Medical Center, Jerusalem, Israel. ISNI: 0000 0001 2221 2926. GRID: grid.17788.31 LeukoDx, Jerusalem, Israel Abionic SA, Lausanne, Switzerland Swiss Federal Laboratories (Empa), St. Gallen, Switzerland Pathophysiology of injury induced immunosuppression (PI3) Lab, Lyon 1 University / Hospices Civils de Lyon / bioMérieux, Lyon, France Negovsky V.A. Research Institute of General Reanimatology, Moscow, Russia University Hospital Basel, Basel, Switzerland. GRID: grid.410567.1 UNIFESP, Sao Paulo, Brazil. ISNI: 0000 0001 0514 7202. GRID: grid.411249.b Albert Einstein Hospital, Sao Paulo, Brazil. ISNI: 0000 0001 0385 1941. GRID: grid.413562.7 Sírio Libanês Hospital, Sao Paulo, Brazil Faculty of Medicine and Health Örebro University, Örebro, Sweden. ISNI: 0000 0001 0738 8966. GRID: grid.15895.30 Department of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden. ISNI: 0000 0000 9241 5705. GRID: grid.24381.3c Faculty of Medicine and Health, Örebro, Sweden Center for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden. ISNI: 0000 0000 9241 5705. GRID: grid.24381.3c Erasmus Medical Center, Rotterdam, Netherlands. ISNI: 000000040459992X. GRID: grid.5645.2 University Witten/Herdecke, Witten, Germany. ISNI: 0000 0000 9024 6397. GRID: grid.412581.b Maasstad Ziekenhuis, Rotterdam, Netherlands. ISNI: 0000 0004 0460 0556. GRID: grid.416213.3 Intermountain Healthcare, Salt Lake City, USA. ISNI: 0000 0004 0460 774X. GRID: grid.420884.2 Immunexpress, Seattle, USA Lewisham and Greenwich NHS Trust, London, UK. GRID: grid.429537.e Wirral trust, Merseyside, UK RLBUHT, Liverpool, UK Department of Emergency Medicine, Odense University Hospital, Odense C, Denmark. ISNI: 0000 0004 0512 5013. GRID: grid.7143.1 Department of Respiratory Medicine, Odense University Hospital, Odense C, Denmark. ISNI: 0000 0004 0512 5013. GRID: grid.7143.1 Department of Anaesthesiology and Intensive Care Medicine, Odense University Hospital, Odense C, Denmark. ISNI: 0000 0004 0512 5013. GRID: grid.7143.1 Bucharest Clinical Emergency Hospital, Bucharest, Romania Fundeni Clinical Institute, Bucharest, Romania. ISNI: 0000 0004 0540 9980. GRID: grid.415180.9 Amsterdam Medical Center, Amsterdam, Netherlands. ISNI: 0000000404654431. GRID: grid.5650.6 University Medical Center Utrecht, Utrecht, Netherlands. ISNI: 0000000090126352. GRID: grid.7692.a Bakirkoy Dr.Sadi Konuk Training and Research Hospital, Istanbul, Turkey. ISNI: 0000 0004 0419 1043. GRID: grid.414177.0 King Saud bin Abdulaziz University for Health Sciences and King Abdullah International Medical Research Center, Riyadh, Saudi Arabia. ISNI: 0000 0004 0608 0662. GRID: grid.412149.b Assaf Harofeh MC, Beer Yaakov, Israel Jena University Hopital, Jena, Germany. ISNI: 0000 0001 1939 2794. GRID: grid.9613.d Prince of Songkla University, Hat Yai, Thailand. ISNI: 0000 0004 0470 1162. GRID: grid.7130.5 Division of Critical Care Medicine, Hat Yai, Thailand Glasgow Royal Infirmary, Glasgow, UK. ISNI: 0000 0000 9825 7840. GRID: grid.411714.6 University Hospital and Faculty of Medicine Ostrava University, Ostrava, Czech Republic. ISNI: 0000 0004 0609 0692. GRID: grid.412727.5 Institute of Biostatistics and analyses, Masaryk University, Brno, Czech Republic. ISNI: 0000 0001 2194 0956. GRID: grid.10267.32 Università degli studi di Pavia, scuola di specialità: Anestesia e Rianimazione, Pavia, Italy. ISNI: 0000 0004 1762 5736. GRID: grid.8982.b UOC Anestesia e Rianimazione Ospedale Civile di Vigevano, AO Pavia, Vigevano, Italy Università degli studi di Pavia, Pavia, Italy. ISNI: 0000 0004 1762 5736. GRID: grid.8982.b Hospital O’horan, Mérida, Mexico Department of Anaesthesiology and Intensive Therapy, Medical University, Wroclaw, Poland. ISNI: 0000 0001 1090 049X. GRID: grid.4495.c AKPA, Waltham, USA St. Paul’s Hospital, Vancouver, Canada. ISNI: 0000 0000 8589 2327. GRID: grid.416553.0 University of Medicine and Pharmacy “Carol Davila”, Bucharest, Romania. ISNI: 0000 0000 9828 7548. GRID: grid.8194.4 Acedemisch Medisch Centrum, Amsterdam, Netherlands University Hospital of Greifswald, Greifswald, Germany. ISNI: 0000 0000 9116 8976. GRID: grid.412469.c Division of Infection Control and Prevention, Osaka University Graduate School of Medicine, Suita, Japan. ISNI: 0000 0004 0373 3971. GRID: grid.136593.b Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Suita, Japan. ISNI: 0000 0004 0373 3971. GRID: grid.136593.b Department of Emergency Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan. ISNI: 0000 0000 8902 2273. GRID: grid.174567.6 Hospital Clínico Universitario de Valladolid, Valladolid, Spain. ISNI: 0000 0000 9274 367X. GRID: grid.411057.6 Jena University Hospital, Jena, Germany. ISNI: 0000 0000 8517 6224. GRID: grid.275559.9 Medica Superspecialty Hospital, Kolkata, West Bengal India DMC, Detroit, USA. ISNI: 0000 0001 0088 6903. GRID: grid.413184.b Wayne State University, Detroit, USA. ISNI: 0000 0001 1456 7807. GRID: grid.254444.7 Scientific Institute of Public Health (WIV-ISP), Brussels, Belgium. ISNI: 0000 0004 0635 3376. GRID: grid.418170.b Ghent University, Ghent, Belgium. ISNI: 0000 0001 2069 7798. GRID: grid.5342.0 Erasme University, Brussels, Belgium QualityLabs Bt GmbH, Nuremberg, Germany B.Braun Melsungen AG, Melsungen, Germany. ISNI: 0000 0001 0699 8877. GRID: grid.462046.2 Dr. Roschke medical marketing GmbH, Cologne, Germany Nakhonpathom hospital, Nakhonpathom, Thailand Lithuanian University of Health Sciences, Kaunas,, Lithuania. ISNI: 0000 0004 0432 6841. GRID: grid.45083.3a University Hospital North Midlands, Stoke-on-Trent, UK EPS Charles-Nicolle, Bab Saadoun, Tunisia Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi County, Taiwan Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands. ISNI: 0000000084992262. GRID: grid.7177.6 Academic Medical Center, University of Amsterdam, Center for Experimental and Molecular Medicine, Amsterdam, Netherlands Department of Intensive Care Medicine, University Medical Center Utrecht, Utrecht, Netherlands. ISNI: 0000000090126352. GRID: grid.7692.a Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands. ISNI: 0000000404654431. GRID: grid.5650.6 Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, Netherlands. ISNI: 0000000090126352. GRID: grid.7692.a NHS Greater Glasgow and Clyde, Glasgow, UK. ISNI: 0000 0001 0523 9342. GRID: grid.413301.4 Health Protection Scotland, Glasgow, UK. ISNI: 0000 0001 2232 4338. GRID: grid.413893.4 Public Health England, London, UK. ISNI: 0000 0001 2196 8713. GRID: grid.9004.d Fukuoka University Hospital, Fukuoka, Japan. ISNI: 0000 0004 0594 9821. GRID: grid.411556.2 King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia. ISNI: 0000 0004 0608 0662. GRID: grid.412149.b Toxicological Research Center, Department of Clinical Toxicology, Loghman-Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. GRID: grid.411600.2 St. Elisabeth Hospital, Tilburg, Netherlands. GRID: grid.416373.4 Mongi Slim University Hospital, La Marsa, Tunisia University of Athens, Medical School, Athens, Greece. ISNI: 0000 0001 2155 0800. GRID: grid.5216.0 Korgialeneion Benakeion Hospital, Athens, Greece University of Thrace, Alexandroupolis, Greece. ISNI: 0000 0001 2170 8022. GRID: grid.12284.3d Aghios Dimitrios Hospital, Thessaloniki, Greece Tzaneion Hospital, Piraeus, Greece G.Gennimatas General Hospital, Thessaloniki, Greece. GRID: grid.414012.2 University of Ioannina, Ioannina, Greece. ISNI: 0000 0001 2108 7481. GRID: grid.9594.1 G.Papanikolaou General Hospital, Thessaloniki, Greece. ISNI: 0000 0004 0576 574X. GRID: grid.415248.e University of Patras, Patras, Greece. ISNI: 0000 0004 0576 5395. GRID: grid.11047.33 Hospital Universitario La Paz, Madrid, Spain. ISNI: 0000 0000 8970 9163. GRID: grid.81821.32 Centro Hospitalar São João, Porto, Portugal. ISNI: 0000 0000 9375 4688. GRID: grid.414556.7 PSMMC, Riyadh, Saudi Arabia UNIKLINIKUM JENA, JENA, Germany King Fahad Medical City, Riyadh, Saudi Arabia. ISNI: 0000 0004 0593 1832. GRID: grid.415277.2 Addenbrooke’s Hospital, Cambridge, UK. ISNI: 0000 0004 0622 5016. GRID: grid.120073.7 University of Cambridge, Cambridge, UK. ISNI: 0000000121885934. GRID: grid.5335.0 Royal United Hospital, Bath, UK. ISNI: 0000 0004 0417 0728. GRID: grid.416091.b Salford Royal Hospital, London, UK. ISNI: 0000 0000 8535 2371. GRID: grid.415721.4 Hennepin County Medical Center, Minneapolis, USA. ISNI: 0000 0000 9206 4546. GRID: grid.414021.2 CHU Dupuytren, Limoges, France. ISNI: 0000 0001 1481 5225. GRID: grid.412212.6 St Luc University Hospital, Brussels, Belgium. ISNI: 0000 0004 0461 6320. GRID: grid.48769.34 CHUV, Lausanne, Switzerland. ISNI: 0000 0001 0423 4662. GRID: grid.8515.9 Hospital Clinic of Barcelona, Barcelona, Spain. ISNI: 0000 0000 9635 9413. GRID: grid.410458.c Hospital Clínico San Carlos, Madrid, Spain. ISNI: 0000 0001 0671 5785. GRID: grid.411068.a Université François Rabelais and CHU Bretonneau, Tours, France. ISNI: 0000 0001 2182 6141. GRID: grid.12366.30 Groupe Hospitalier Pitié-Salpêtrière, Paris, France. ISNI: 0000 0001 2150 9058. GRID: grid.411439.a MedImmune, Gaithersburg, USA. GRID: grid.418152.b Xanthi General Hospital, Xanthi, Greece Royal Infirmary of Edinburgh, Edinburgh, UK. ISNI: 0000 0001 0709 1919. GRID: grid.418716.d Western General Hospital, Edinburgh, UK. ISNI: 0000 0004 0624 9907. GRID: grid.417068.c Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy. ISNI: 0000 0004 1762 5736. GRID: grid.8982.b Centre Hospitalier Universitaire Dijon, Dijon, France. GRID: grid.31151.37 Marmara University Pendik Teaching and Research Hospital, Istanbul, Turkey. ISNI: 0000 0001 0668 8422. GRID: grid.16477.33 Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK. GRID: grid.419135.b University College, London, UK Cairo University, Giza, Egypt. ISNI: 0000 0004 0639 9286. GRID: grid.7776.1 University hospital Center of La Rabta, Tunis, Tunisia V.A. Negovsky Research Institute of General Reanimatology, Moscow, Russia N.V. Sklifosofsky Institute of Emergency Medicine, Moscow, Russia NN Burdenko Main Military Hospital, Moscow, Russia Novartis Pharmaceuticals, San Carlos, USA. ISNI: 0000 0004 0439 2056. GRID: grid.418424.f Nektar Therapeutics, San Francisco, CA USA. ISNI: 0000 0004 0410 3955. GRID: grid.476522.0 Hospital Clinic, Barcelona, Spain. ISNI: 0000 0000 9635 9413. GRID: grid.410458.c Maine Medical Center, Portland, USA. GRID: grid.240160.1 Medical University of Vienna, Vienna, Austria. ISNI: 0000 0000 9259 8492. GRID: grid.22937.3d HIA Percy, Clamart, France. ISNI: 0000 0004 1795 3756. GRID: grid.414028.b Pherecydes Pharma, Romainville, France Hôpital Reine Astrid, Brussels, Belgium CHU Liege, Liege, Belgium. ISNI: 0000 0000 8607 6858. GRID: grid.411374.4 CH Saint Jospeh Saint Luc, Lyon, France Hamad Medical Corporation, Doha, Qatar. ISNI: 0000 0004 0571 546X. GRID: grid.413548.f MUI, Innsbruck, Austria. ISNI: 0000 0000 8853 2677. GRID: grid.5361.1 Academic Medical Centre, Amsterdam, Netherlands. ISNI: 0000000404654431. GRID: grid.5650.6 Academic Medical Center Amsterdam, Amsterdam, Netherlands. ISNI: 0000000404654431. GRID: grid.5650.6 Sanquin, Amsterdam, Netherlands. ISNI: 0000 0001 2234 6887. GRID: grid.417732.4 KAT Hospital Athens, Kifisia, Greece. ISNI: 0000 0004 0622 8129. GRID: grid.415070.7 ICU-B, KAT Hospital Kifisia, Athens, Greece Hokkaido University Hospital, Sapporo, Japan. ISNI: 0000 0004 0378 6088. GRID: grid.412167.7 Tohoku University Graduate School of Medicine, Sendai, Japan. ISNI: 0000 0001 2248 6943. GRID: grid.69566.3a Tokyo Medical and Dental University Hospital of Medicine, Tokyo, Japan. GRID: grid.474906.8 National Hospital Organization Disaster Medical Center, Tokyo, Japan. ISNI: 0000 0004 0569 9594. GRID: grid.416797.a Keio University School of Medicine, Tokyo, Japan. ISNI: 0000 0004 1936 9959. GRID: grid.26091.3c Osaka University Graduate School of Medicine, Osaka, Japan. ISNI: 0000 0004 0373 3971. GRID: grid.136593.b Rinku General Medical Center, Osaka, Japan Kinki University Faculty of Medicine, Osaka, Japan. ISNI: 0000 0004 1936 9967. GRID: grid.258622.9 Yokohama City University Graduate School of Medicine, Yokohama, Japan. ISNI: 0000 0001 1033 6139. GRID: grid.268441.d Faculty of Medicine, Fukuoka University, Fukuoka, Japan. ISNI: 0000 0001 0672 2176. GRID: grid.411497.e National Center For Global Health and Medicine, Tokyo, Japan. ISNI: 0000 0004 0489 0290. GRID: grid.45203.30 Tokyo Women’s Medical University, Tokyo, Japan. ISNI: 0000 0001 0720 6587. GRID: grid.410818.4 Odessa National Medical University, Odessa, Ukraine. GRID: grid.445907.b Hopital Sacré-Coeur de Montréal, Montreal, Canada. ISNI: 0000 0001 2160 7387. GRID: grid.414056.2 Xanthi General Hospital, Xanth, Greece. GRID: grid.414012.2 Maastricht UMC, Maastricht, Netherlands. GRID: grid.412966.e Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic. ISNI: 0000 0004 0611 0905. GRID: grid.412826.b Sechenov First Moscow Stat Medical University, Moscow, Russia Sheba Medical Center, Tel-Hashomer, Israel. ISNI: 0000 0001 2107 2845. GRID: grid.413795.d Yokohama Municipal Citizen’s Hospital, Yokohama, Japan. ISNI: 0000 0004 0377 5418. GRID: grid.417366.1 Hayama Heart Center, Hayama, Japan Yokohama City University Hospital, Yokohama, Japan. ISNI: 0000 0004 1767 0473. GRID: grid.470126.6 Institute of Ageing and Chronic Disease, Liverpool, UK Institute of Infection and Global Health, Liverpool, UK Department of Haematology, Royal Liverpool University Hospital (RLUH), Liverpool, UK. ISNI: 0000 0004 0417 2395. GRID: grid.415970.e Hôpital du Sacré-Coeur de Montréal, Montreal, Canada. ISNI: 0000 0001 2160 7387. GRID: grid.414056.2 Evelina London Children’s Hospital, London, UK St Thomas Hospital, London, UK. GRID: grid.425213.3 Intensive Care Unit, University of Ferrara, Italy, Ferrara, Italy. ISNI: 0000 0004 1757 2064. GRID: grid.8484.0 Department of Intensive Care, Erasme Hospital, Université Libre de Bruxelles, Bruxelles, Belgium Hippokration General Hospital Thessaloniki, Thessaloniki, Greece. ISNI: 0000 0004 0621 2899. GRID: grid.414122.0 Morriston Hospital, Swansea, UK. ISNI: 0000 0004 0649 0266. GRID: grid.416122.2 Central London School of Anaesthesia and Intensive Care Medicine, London, UK University of the Sunshine Coast, Maroochydore, Australia. ISNI: 0000 0001 1555 3415. GRID: grid.1034.6 University of Edinburgh, Edinburgh, UK. ISNI: 0000 0004 1936 7988. GRID: grid.4305.2 John Radcliffe Hospital, Oxford, UK. ISNI: 0000 0001 2306 7492. GRID: grid.8348.7 Copenhagen University Hospital, Copenhagen, Denmark. ISNI: 0000 0004 0646 7373. GRID: grid.4973.9 Peterborough NHS Trust, Peterborough, UK Aarhus University, Aarhus, Denmark. ISNI: 0000 0001 1956 2722. GRID: grid.7048.b Hospital de Sao Paulo, Sao Paulo, Brazil. GRID: grid.413463.7 Royal Brompton & Harefield NHS Trust, London, UK. ISNI: 0000 0004 0581 2008. GRID: grid.451052.7 Barts Heart Centre, London, UK University of Sao Paulo, Brazi, Sao Paulo, Brazil. ISNI: 0000 0004 1937 0722. GRID: grid.11899.38 Juntendo University Hospital, Tokyo, Japan. GRID: grid.411966.d Saitama Medical Center, Jichi Medical University, Saitama, Japan. ISNI: 0000000123090000. GRID: grid.410804.9 Gunma University Hospital, Maebashi, Japan. ISNI: 0000 0004 0595 7039. GRID: grid.411887.3 Yokohama City Minato Red Cross Hospital, Yokohama, Japan Research Institution for Cardiology, Tomsk, Russia Siberian State Medical University, Tomsk, Russia. ISNI: 0000 0001 0027 1685. GRID: grid.412593.8 The Hillingdon Hospitals NHS Foundation Trust, Middlesex, UK. ISNI: 0000 0004 0476 7073. GRID: grid.440199.1 University Hospital Rio Hortega, Valladolid, Spain. ISNI: 0000 0001 1842 3755. GRID: grid.411280.e Erasmus MC, Rotterdam, Netherlands. ISNI: 000000040459992X. GRID: grid.5645.2 Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates. ISNI: 0000 0004 1773 3278. GRID: grid.415670.1 Intensive Care Unit, St. Boniface Hospital, Verona, Italy University of Pittsburgh, Pittsburgh, USA. ISNI: 0000 0004 1936 9000. GRID: grid.21925.3d Carnegie Mellon University, Pittsburgh, USA. ISNI: 0000 0001 2097 0344. GRID: grid.147455.6 Valme University Hospital, Seville, Spain. ISNI: 0000 0004 1768 1690. GRID: grid.412800.f CHU Amiens, Amiens, France. ISNI: 0000 0004 0593 702X. GRID: grid.134996.0 CH Beauvais, Beauvais, France Réanimation polyvalente, Le Havre, France CH Roubaix, Roubaix, France. ISNI: 0000 0004 0608 7784. GRID: grid.477297.8 CH Cotentin, Cherbourg, France CHU Rouen, Rouen, France. GRID: grid.41724.34 CHU Lille, Lille, France. ISNI: 0000 0004 0471 8845. GRID: grid.410463.4 CHU Caen, Caen, France. ISNI: 0000 0004 0472 0160. GRID: grid.411149.8 University Medical Center Hamburg-Eppendorf, Hamburg, Germany. ISNI: 0000 0001 2180 3484. GRID: grid.13648.38 Brugmann Hospital, Brussels, Belgium. ISNI: 0000 0004 0469 8354. GRID: grid.411371.1 Hospital Universitario del Tajo, Aranjuez, Spain Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Spain. ISNI: 0000 0004 1765 5855. GRID: grid.411338.c Hospital Universitario de San Carlos, Madrid, Spain. ISNI: 0000 0001 0671 5785. GRID: grid.411068.a Klinikum rechts der Isar, Technical University of Munich, Munich, Germany. ISNI: 0000000123222966. GRID: grid.6936.a Department of Intensive Care Medicine, University Hospital Bern, Bern, Switzerland. ISNI: 0000 0004 0479 0855. GRID: grid.411656.1 Institute of Clinical Sciences at the Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, Sweden St George’s Healthcare NHS Trust, London, UK. GRID: grid.451349.e Karolinska Institutet, Stockholm, Sweden. ISNI: 0000 0004 1937 0626. GRID: grid.4714.6 Wenzhou Medical University, Wenzhou, Zheijang China. ISNI: 0000 0001 0348 3990. GRID: grid.268099.c Department of Intensive Care, Austin Hospital, Melbourne, VIC Australia. ISNI: 0000 0001 0162 7225. GRID: grid.414094.c Policlinico Modena, Bologna, Italy. ISNI: 0000 0004 1769 5275. GRID: grid.413363.0 Clinical Hospital Sveti Duh, Zagreb, Croatia The Canberra Hospital, Hughes, ACT Australia. ISNI: 0000 0000 9984 5644. GRID: grid.413314.0 Australian National University Medical School, Canberra, Australia. ISNI: 0000 0001 2180 7477. GRID: grid.1001.0 Lapeyronie University Hospital, Montpellier, France. ISNI: 0000 0004 0638 8990. GRID: grid.411572.4 Brigham and Women’s Hospital, Boston, USA. ISNI: 0000 0004 0378 8294. GRID: grid.62560.37 Trexin Medical, Chicago, USA University of Colorado and Denver Health, Denver, USA. ISNI: 0000000107903411. GRID: grid.241116.1 Beth Isreal Deaconess, Boston, USA Centro Hospitalar do Porto, Porto, Portugal. ISNI: 0000 0004 0392 7039. GRID: grid.418340.a University Hospital, Ghent, Belgium. ISNI: 0000 0004 0626 3303. GRID: grid.410566.0 City Clinical Hospital 40, Yekaterinburg, Russia University Hospital Muenster, Muenster, Germany. ISNI: 0000 0004 0551 4246. GRID: grid.16149.3b Marienhospital Osnabrück, Osnabrück, Germany Charité, University of Berlin, Berlin, Germany Sapienza University of Rome, Rome, Italy. GRID: grid.7841.a University Hospital of Muenster, Muenster, Germany. ISNI: 0000 0004 0551 4246. GRID: grid.16149.3b Erasmus MC University Hospital Rotterdam, Rotterdam, Netherlands. ISNI: 000000040459992X. GRID: grid.5645.2 Medical Research Institute of New Zealand, Wellington, New Zealand. ISNI: 0000 0004 0445 6830. GRID: grid.415117.7 Monash University, Melbourne, Australia. ISNI: 0000 0004 1936 7857. GRID: grid.1002.3 Austin Hospital, Melbourne, Australia. ISNI: 0000 0001 0162 7225. GRID: grid.414094.c Wellington Regional Hospital, Wellington, New Zealand. ISNI: 0000 0000 8862 6892. GRID: grid.416979.4 Australian and New Zealand Intensive Care Research Centre, Melbourne, Australia Princess of Wales Hospital, Bridgend, UK. ISNI: 0000 0004 0648 9337. GRID: grid.415249.f Imperial College London, London, UK. ISNI: 0000 0001 2113 8111. GRID: grid.7445.2 Glan Clwyd Hospital, Bodelwyddan, UK. ISNI: 0000 0000 9831 5916. GRID: grid.415564.7 University Hospital Galway, Galway, Ireland. ISNI: 0000 0004 0617 9371. GRID: grid.412440.7 Albert Schweitzer State Hospital, Rio de Janeiro, Brazil Tan Tock Seng Hospital, Singapore, Singapore. GRID: grid.240988.f National Neuroscience Institute, Singapore, Singapore. ISNI: 0000 0004 0636 696X. GRID: grid.276809.2 Erasmus Medical Centre, Rotterdam, Netherlands. ISNI: 000000040459992X. GRID: grid.5645.2 Centro Hospitalar Tamega e Sousa, Penafiel, Portugal. GRID: grid.466592.a Unidade Local de Saude do Alto Minho, Viana do Castelo, Portugal South Tees NHS Trust, Middlesbrough, UK Ikazia Hospital, Rotterdam, Netherlands. ISNI: 0000 0004 0568 7120. GRID: grid.414565.7 Sheffiled Teaching Hospitals, Sheffield, UK Whiston Hospital, St Helens & Knowsley, UK. ISNI: 0000 0004 0417 1894. GRID: grid.417083.9 University Hospital Duesseldorf, Düsseldorf, Germany. ISNI: 0000 0000 8922 7789. GRID: grid.14778.3d Charite University Hospital, Berlin, Germany. ISNI: 0000 0001 2218 4662. GRID: grid.6363.0 Royal London Hospital, London, UK. ISNI: 0000 0001 0738 5466. GRID: grid.416041.6 Aurelia and European Hospital, Rome, Italy. GRID: grid.414645.6 Istanbul University Cerrahpasa Medical School, Istanbul, Turkey. ISNI: 0000 0001 2166 6619. GRID: grid.9601.e Danube University Krems, Krems, Austria. ISNI: 0000 0001 2108 5830. GRID: grid.15462.34 University Hospital St. Poelten, St. Poelten, Austria Teaching Hospital Policlinico S.Orsola-Malpighi, Bologna, Italy. GRID: grid.412311.4 Department of Nephrology, Dialysis, Hypertension, Bologna, Italy Science and Technology Park for Medicine, Mirandola, Italy Aferetica, Bologna, Italy San Marco Hospital, Zingonia, Italy CytoSorbents, Monmouth Junction, USA. GRID: grid.428484.6 Klinikum Emden, Emden, Germany University Hospital Eppendorf, Hamburg, Germany. ISNI: 0000 0001 2180 3484. GRID: grid.13648.38 Aurelia Hospital /European Hospital, Rome, Italy. GRID: grid.414077.1 King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia. ISNI: 0000 0001 2191 4301. GRID: grid.415310.2 GPR Klinikum Ruesselsheim, Ruesselsheim, Hessen Germany Jikei University School of Medicine, Tokyo, Japan. ISNI: 0000 0001 0661 2073. GRID: grid.411898.d Kyoto University, Kyoto, Japan. ISNI: 0000 0004 0372 2033. GRID: grid.258799.8 Osaka University, Osaka, Japan. ISNI: 0000 0004 0373 3971. GRID: grid.136593.b Guy’s & St Thomas’ NHS Foundation Trust, London, UK. GRID: grid.420545.2 King’s College, London, UK. ISNI: 0000 0001 2322 6764. GRID: grid.13097.3c Hospital de Santa Maria, Lisbon, Portugal. ISNI: 0000 0001 2295 9747. GRID: grid.411265.5 ErasmusMC, Rotterdam, Netherlands. ISNI: 000000040459992X. GRID: grid.5645.2 Gazi University Medical Faculty, Ankara, Turkey. ISNI: 0000 0001 2169 7132. GRID: grid.25769.3f Gazi University School of Medicine, Critical Care Fellowship Programme, Ankara, Turkey Gazi University School of Medicine Biochemistry Department, Ankara, Turkey. ISNI: 0000 0001 2169 7132. GRID: grid.25769.3f Fundación Clínica Medica Sur, Mexico City, Mexico Lund University and Skane University Hospital, Lund, Sweden. GRID: grid.411843.b Radboudumc, Nijmegen, Netherlands. ISNI: 0000 0004 0444 9382. GRID: grid.10417.33 Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium. ISNI: 0000 0001 2348 0746. GRID: grid.4989.c The Royal Surrey County Hospital, Guildford, UK. ISNI: 0000 0004 0417 0648. GRID: grid.416224.7 Royal National Orthopaedic Hospital, Middlesex, UK. ISNI: 0000 0004 0417 7890. GRID: grid.416177.2 Barts Health NHS Trust, London, UK. ISNI: 0000 0001 0372 5777. GRID: grid.139534.9 Queen Mary University of London, London, UK. ISNI: 0000 0001 2171 1133. GRID: grid.4868.2 Asan medical center, Seoul, South Korea. ISNI: 0000 0001 0842 2126. GRID: grid.413967.e Trakya Univ, Edirne, Turkey. ISNI: 0000 0001 2342 6459. GRID: grid.411693.8 General Directorate of Health Services, Ministry of Health, Ankara, Turkey. GRID: grid.415700.7 AnkaraNKARA Research and Training Hospital, Ankara, Turkey Department of Biostatistics, Faculty of Medicine, Ankara University, Ankara, Turkey. ISNI: 0000000109409118. GRID: grid.7256.6 Ankara Research and Training Hospital, Ankara, Turkey. ISNI: 0000 0004 0642 6432. GRID: grid.413783.a MC Into-Sana, Odessa, Ukraine Glan Clwyd Hospital, Rhyl, UK. ISNI: 0000 0000 9831 5916. GRID: grid.415564.7 Fondazione IRCCS Ca’ Granda, Maggiore Policlinico Hospital, Milan, Italy University of Ferrara, Sant’Anna Hospital, Ferrara, Italy Aerogen, Galway, Ireland Kaplan Medical Centre, Rehovot, Israel West Virginia University, Morgantown, West Virginia USA. ISNI: 0000 0001 2156 6140. GRID: grid.268154.c Rihard Knafelj, Ljubljana, Slovenia Corporació Sanitària i Universitària Parc Taulí, Universitat Autònoma de Barcelona, CIBER Enfermedades Respiratorias, Sabadell, Barcelona, Spain. GRID: grid.7080.f Dalhousie University, Halifax, Canada. ISNI: 0000 0004 1936 8200. GRID: grid.55602.34 Ernst-Moritz-Arndt-Universität, Greifswald, Germany. GRID: grid.5603.0 Ghent University Hospital, Gent, Belgium. ISNI: 0000 0004 0626 3303. GRID: grid.410566.0 Universidade de São Paulo, São Paulo, Brazil. ISNI: 0000 0004 1937 0722. GRID: grid.11899.38 Hospital La Paz, Madrid, Spain. ISNI: 0000 0000 8970 9163. GRID: grid.81821.32 Institute of Mother and Child, Chisinau mun., Moldova Institute of Emergency Medicine, Chisinau mun., Moldova State University of Medicine and Pharmacy, Chisinau mun., Moldova Cardarelli Hospital, Naples, Italy. GRID: grid.413172.2 San Paolo Hospital, Naples, Italy National University of Ireland, Galway, Galway City, Ireland. ISNI: 0000 0004 0488 0789. GRID: grid.6142.1 Mount Sinai Hospital, Toronto, Canada. ISNI: 0000 0004 0473 9881. GRID: grid.416166.2 Gazi University School of Medicine Respiratory Medicine and Critical Care Department, Ankara, Turkey. ISNI: 0000 0001 2169 7132. GRID: grid.25769.3f Gazi University School of Medicine, Internal Medicine Critical Care Department, Ankara, Turkey Gazi University School of Medicine, Geriatrics Department, Ankara, Turkey Chulalongkorn University, Bangkok, Thailand. ISNI: 0000 0001 0244 7875. GRID: grid.7922.e Carmel, Lady Davis Medical Center, Haifa, Israel. GRID: grid.471000.2 Duke University, Durham, USA. ISNI: 0000 0004 1936 7961. GRID: grid.26009.3d Mayo Clinic, Rochester, USA. ISNI: 0000 0004 0459 167X. GRID: grid.66875.3a St Helens and Knoowsley, Prescot, UK Royal Infirmary, Edinburgh, UK. ISNI: 0000 0001 0709 1919. GRID: grid.418716.d Alexandria Universitry General Hospital, Alexandria, Egypt. ISNI: 0000 0001 2260 6941. GRID: grid.7155.6 University Hospital North Middlands, Stoke On Trent, UK. ISNI: 0000 0004 0641 4263. GRID: grid.415598.4 Medica Sur, Mexico City, Mexico. GRID: grid.414741.3 Instituto Nacional de Rehabilitacion, Mexico City, Mexico. ISNI: 0000 0004 0633 2911. GRID: grid.419223.f University of Padua, Padua, Italy. ISNI: 0000 0004 1757 3470. GRID: grid.5608.b Sant Antony hospital, Padua, Italy HCMC, Minneapolis, USA. ISNI: 0000 0000 9206 4546. GRID: grid.414021.2 University of Minnesota, Minneapolis, USA. ISNI: 0000000419368657. GRID: grid.17635.36 Viecuri Medical Center, Venlo, Netherlands. ISNI: 0000 0004 0477 5022. GRID: grid.416856.8 University of Hawaii, John A. Burns School of Medicine, Honolulu, USA. ISNI: 0000 0001 2188 0957. GRID: grid.410445.0 Respiratory Motion Inc., Waltham, USA Massachusetts General Hospital, Boston, USA. ISNI: 0000 0004 0386 9924. GRID: grid.32224.35 AO Desio e Vimercate, Vimercate, Italy AO Crema, Crema, Italy University of Milan-Bicocca, Monza, Italy. ISNI: 0000 0001 2174 1754. GRID: grid.7563.7 UT Health Science Center at Houston, Houston, TX USA. ISNI: 0000 0000 9206 2401. GRID: grid.267308.8 University of Hawaii, John A. Burns School of Medicine, Honolulu, HI USA. ISNI: 0000 0001 2188 0957. GRID: grid.410445.0 Respiratory Motion Inc., Waltham, MA USA Massachusetts General Hospital, Boston, MA USA. ISNI: 0000 0004 0386 9924. GRID: grid.32224.35 Swisstom AG, Landquart, Switzerland Kliniken der Stadt Köln, Pneumology and Critical Care Medicine, Witten / Herdecke University, Ostmerheimer Str. 200, 51109 Cologne, Germany. ISNI: 0000 0000 9024 6397. GRID: grid.412581.b Kliniken der Stadt Köln, Pneumology and Critical Care Medicine, Witten/ Herdecke University, Ostmerheimer Str. 200, 51109 Cologne, Germany. ISNI: 0000 0000 9024 6397. GRID: grid.412581.b ARDS and ECMO Center Köln-Merheim, Cologne, Germany Swisstom, Chur, Switzerland Sahlgrenska Univ Hospital, Göteborg, Sweden. ISNI: 000000009445082X. GRID: grid.1649.a Second University of Naples, Naples, Italy. ISNI: 0000 0001 2200 8888. GRID: grid.9841.4 University of Sassari, Sassari, Italy. ISNI: 0000 0001 2097 9138. GRID: grid.11450.31 University of Saerno, Salerno, Italy East Surrey Hospital, Surrey and Sussex NHS Trust, Surrey, UK Mount Sinai Hospital and University of Toronto, Toronto, Canada. ISNI: 0000 0004 0473 9881. GRID: grid.416166.2 University Health Network-Toronto General Hospital and Univeristy of Toronto, Toronto, Canada. ISNI: 0000 0001 0661 1177. GRID: grid.417184.f Papworth Hospital, Cambridge, UK. ISNI: 0000 0004 0399 2308. GRID: grid.417155.3 King’s College Hospital NHS Foundation Trust, London, UK. ISNI: 0000 0004 0489 4320. GRID: grid.429705.d Meijer Heart & Vascular Institute, Grand Rapids, USA Glenfield Hospital, UHL, Leicester, UK. ISNI: 0000 0004 0648 9396. GRID: grid.416025.4 National University Hospital, Singapore, Singapore. ISNI: 0000 0004 0621 9599. GRID: grid.412106.0 National University Singapore, Singapore, Singapore. ISNI: 0000 0001 2180 6431. GRID: grid.4280.e Mayo Clinic, Phoenix, AZ USA. ISNI: 0000 0000 8875 6339. GRID: grid.417468.8 University of Pittsburgh, Pittsburgh, PA USA. ISNI: 0000 0004 1936 9000. GRID: grid.21925.3d Vall D’Hebron University Hospital, Barcelona, Spain. ISNI: 0000 0001 0675 8654. GRID: grid.411083.f Universitat Autonoma de Barcelona, Barcelona, Spain. GRID: grid.7080.f George P. Livanos and Marianthi Simou Laboratories, Athens, Greece University of Patras, Rio, Achaia Greece. ISNI: 0000 0004 0576 5395. GRID: grid.11047.33 University of Ferrara, Ferrara, Italy. ISNI: 0000 0004 1757 2064. GRID: grid.8484.0 University of Bari, Bari, Italy. ISNI: 0000 0001 0120 3326. GRID: grid.7644.1 CHU HJRA, Antananarivo, Madagascar Réanimation médicale, Centre Hospitalier Universitaire, Amiens, France. ISNI: 0000 0004 0593 702X. GRID: grid.134996.0 Cardio-Pulmonary Department, Pulmonary Division, Heart Institute (Incor), University of São Paulo, São Paulo, Brazil. ISNI: 0000 0004 1937 0722. GRID: grid.11899.38 Royal Brompton Hospital, London, UK. GRID: grid.439338.6 Musashino Red Cross Hospital, Tokyo, Japan. ISNI: 0000 0000 9887 307X. GRID: grid.416332.1 JSEPTIC Clinical Trial Group, Tokyo, Japan University of Liverpool, Liverpool, UK. ISNI: 0000 0004 1936 8470. GRID: grid.10025.36 Royal Liverpool University Hospital, Liverpool, UK. ISNI: 0000 0004 0417 2395. GRID: grid.415970.e Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, Spain. ISNI: 0000 0000 8816 6945. GRID: grid.411048.8 MUMC, Maastricht, Netherlands. GRID: grid.412966.e Vilnius University Hospital Santariskiu Clinics, Vilnius, Lithuania. ISNI: 0000 0004 0567 3159. GRID: grid.426597.b Vilnius University, Faculty of Medicine, Vilnius, Lithuania Mercy University Hospital, Cork, Ireland. ISNI: 0000 0004 0575 9497. GRID: grid.411785.e Hospital Meridional S.A., Cariacica, Brazil Geneva Universtiy Hospital, Geneva, Switzerland. ISNI: 0000 0001 0721 9812. GRID: grid.150338.c Medical University Department, Kantonsspital Aarau, Aarau, Switzerland. ISNI: 0000 0000 8704 3732. GRID: grid.413357.7 Department of Endocrinology, Diabetes and Clinical Nutrition, University Hospital Bern, Bern, Switzerland. ISNI: 0000 0004 0479 0855. GRID: grid.411656.1 Jessa Ziekenhuis, Hasselt, Belgium. ISNI: 0000 0004 0578 1096. GRID: grid.414977.8 Unidade de Saude Local de Castelo Branco, Castelo Branco, Portugal Centro Hospitalar e Universitario de Coimbra, Coimbra, Portugal. ISNI: 0000000106861985. GRID: grid.28911.33 Centro Hospitalar de Vila Nova de Gaia, Vila Nova de Gaia, Portugal. ISNI: 0000 0000 8902 4519. GRID: grid.418336.b Centro Hospitalar do Algarve, Faro, Portugal Instituto Portugues de Oncologia do Porto, Porto, Portugal. GRID: grid.435544.7 Faculdade de Ciencias da Nutricao e Alimentacao da Universidade do Porto, Porto, Portugal. ISNI: 0000 0001 1503 7226. GRID: grid.5808.5 Faculdade de Ciencias da Nutrição e Alimentação da Universidade do Porto, Porto, Portugal. ISNI: 0000 0001 1503 7226. GRID: grid.5808.5 Instituto Português de Oncologia do Porto, Porto, Portugal. ISNI: 0000 0004 0631 0608. GRID: grid.418711.a Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal. ISNI: 0000000106861985. GRID: grid.28911.33 Centro Hospitalar do Baixo Vouga, Aveiro, Portugal Nottingham University Hospital NHS Trust, Nottingham, UK. ISNI: 0000 0001 0440 1889. GRID: grid.240404.6 Prince of Songkla University, Songkla, Thailand. ISNI: 0000 0004 0470 1162. GRID: grid.7130.5 Université de Sherbrooke, Sherbrooke, Canada. ISNI: 0000 0000 9064 6198. GRID: grid.86715.3d University Hospital, Montevideo, Uruguay Queen’s University, Kingston, Canada. ISNI: 0000 0004 1936 8331. GRID: grid.410356.5 University Medical Center Schleswig-Holstein, Kiel, Germany. ISNI: 0000 0004 0646 2097. GRID: grid.412468.d University of Jena, Jena, Germany. ISNI: 0000 0001 1939 2794. GRID: grid.9613.d Aida Hospital, Fukushima, Japan Keiyo Hospital, Tokyo, Japan Shisei Hospital, Saitama, Japan Prince of Songkla University, Hat Yai City, Songkhla Province Thailand. ISNI: 0000 0004 0470 1162. GRID: grid.7130.5 Centro Hospitalar Baixo Vouga, Aveiro, Portugal Department of Cardiothoracic Surgery, George Papanikolaou General Hospital, Thessaloniki, Greece. ISNI: 0000 0004 0576 574X. GRID: grid.415248.e Gülhane Military Medical Academy, Ankara, Turkey. ISNI: 0000 0001 0720 6034. GRID: grid.413460.4 Ankara Mevki Military Hospital, Ankara, Turkey. GRID: grid.461837.f St Bartholomew’s Hospital, London, UK. ISNI: 0000 0000 9244 0345. GRID: grid.416353.6 Aristotle Medical School, Thessaloniki, Greece Tokyo Medical University Hachiosi Medical Center, Tokyo, Japan. ISNI: 0000 0001 0663 3325. GRID: grid.410793.8 Hôpital Louis Mourier, Colombes, France. ISNI: 0000 0001 0273 556X. GRID: grid.414205.6 Laboratoire ILUMENS, Paris, France Institut de Hauts de Seine, Nanterre, France University Hospital Lewisham, London, UK. GRID: grid.439787.6 Queen Elizabeth Hospital, London, UK. GRID: grid.439484.6 Minet Green Health Practice, London, UK Department of Public Health, University of Liège, Liège, Belgium. ISNI: 0000 0001 0805 7253. GRID: grid.4861.b Department of Emergency Medicine, University Hospital of Liège, Liège, Belgium. ISNI: 0000 0000 8607 6858. GRID: grid.411374.4 Department of Medical Biostatistics, University of Liège, Liège, Belgium. ISNI: 0000 0001 0805 7253. GRID: grid.4861.b University Hospital, Philipps University Marburg, Marburg, Germany. ISNI: 0000 0004 1936 9756. GRID: grid.10253.35 Oslo University Hospital, Oslo, Norway. ISNI: 0000 0004 0389 8485. GRID: grid.55325.34 William Harvey Hospital, Ashford, UK. ISNI: 0000 0004 0398 7998. GRID: grid.417122.3 Kansai Medical University Takii Hospital, Moriguchi, Japan. GRID: grid.410783.9 Japanese Red Cross Musashino Hospital, Tokyo, Japan. ISNI: 0000 0004 1762 2623. GRID: grid.410775.0 Medisch Spectrum Twente, Enschede, Netherlands. ISNI: 0000 0004 0399 8347. GRID: grid.415214.7 University Modena, Modena, Italy. ISNI: 0000000121697570. GRID: grid.7548.e Nuovo Ospedale Civile Sant’Agostino Estense, Modena, Italy Faculty of Medicine Alexandria University, Alexandria, Egypt. ISNI: 0000 0001 2260 6941. GRID: grid.7155.6 Victoria Hospital, Kirkcaldy, UK. ISNI: 0000 0004 0624 9667. GRID: grid.416854.a Ziekenhuis Oost-Limburg, Genk, Belgium. ISNI: 0000 0004 0612 7379. GRID: grid.470040.7 ANU Medical School, Canberra, Australia. ISNI: 0000 0001 2180 7477. GRID: grid.1001.0 “Spirito Santo” Hospital, Pescara, Italy. GRID: grid.416240.5 St Lukes International Hospital, Akashi-Chou Chuo-Ku, Japan. GRID: grid.430395.8 Kangwon National University, Chuncheonsi, South Korea. ISNI: 0000 0001 0707 9039. GRID: grid.412010.6 Military Medical Academy, Sofia, Bulgaria. ISNI: 0000 0004 0621 0228. GRID: grid.413126.3 Istanbul University, Medical Faculty of Istanbul, Anesthesiology and Intensive Care, Istanbul, Turkey Istanbul University, Medical Faculty of Istanbul, Department of Neuroradiology, Istanbul, Turkey. ISNI: 0000 0001 2166 6619. GRID: grid.9601.e Istanbul University, Institute of Experimental Medicine, Neuroscience, Istanbul, Turkey. ISNI: 0000 0001 2166 6619. GRID: grid.9601.e Helsinki University Hospital, Helsinki, Finland. ISNI: 0000 0000 9950 5666. GRID: grid.15485.3d North Karelia Central Hospital, Joensuu, Finland. ISNI: 0000 0004 0368 0478. GRID: grid.416446.5 Kuopio University Hospital, Kuopio, Finland. ISNI: 0000 0004 0628 207X. GRID: grid.410705.7 King’s College Hospital, London, UK. ISNI: 0000 0004 0391 9020. GRID: grid.46699.34 Hospital Universitario Puerta del Mar, Cadiz, Spain. ISNI: 0000 0004 1771 1175. GRID: grid.411342.1 Hospital Infanta Cristina, Badajoz, Spain. ISNI: 0000 0004 1771 0842. GRID: grid.411319.f The Ottawa Hospital, Ottawa, Canada. ISNI: 0000 0000 9606 5108. GRID: grid.412687.e Ulaval, Quebec City, Canada UBC, Vancouver, Canada. ISNI: 0000 0001 2288 9830. GRID: grid.17091.3e UManitoba, Winnipeg, Canada OHRI, Ottawa, Canada Ottawa Hospital Research Institute, Ottawa, Canada. ISNI: 0000 0000 9606 5108. GRID: grid.412687.e Cliniques St Luc, Université catholique de Louvain, Brussels, Belgium. ISNI: 0000 0001 2294 713X. GRID: grid.7942.8 Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy. ISNI: 0000 0004 1757 8749. GRID: grid.414818.0 Milan University, Milan, Italy. ISNI: 0000 0004 1757 2822. GRID: grid.4708.b CHU de Nice, Nice, France. ISNI: 0000 0001 2322 4179. GRID: grid.410528.a Regional Hospital, Liberec, Czech Republic. ISNI: 0000 0004 0609 0449. GRID: grid.447961.9 Institute of Experimental Medicine, Prague, Czech Republic. ISNI: 0000 0004 0404 6946. GRID: grid.424967.a University of Glasgow, Glasgow, UK. ISNI: 0000 0001 2193 314X. GRID: grid.8756.c Institute of Neurological Sciences, NHSGGC, Glasgow, UK. ISNI: 0000 0001 0523 9342. GRID: grid.413301.4 Department of Clinical Physics and Bioengineering, NHSGGC, Glasgow, UK. ISNI: 0000 0001 0523 9342. GRID: grid.413301.4 Academic Unit of Anaesthesia, Pain and Critical Care Medicine, University of Glasgow, Glasgow, UK. ISNI: 0000 0001 2193 314X. GRID: grid.8756.c Smartimplant Ltd., Tallinn, Estonia NEMC, Tallinn, Estonia. ISNI: 0000 0004 0631 377X. GRID: grid.454953.a Universite Laval, Quebec, Canada. ISNI: 0000 0004 1936 8390. GRID: grid.23856.3a University of Manitoba, Winnipeg, Canada. ISNI: 0000 0004 1936 9609. GRID: grid.21613.37 Universite de Montreal, Montreal, Canada. ISNI: 0000 0001 2292 3357. GRID: grid.14848.31 University of British Columbia, Vancouver, Canada. ISNI: 0000 0001 2288 9830. GRID: grid.17091.3e Hospital Estadual Getulio Vargas, Rio de Janeiro, Brazil Yonsei University College of Medicine, Seoul, South Korea. ISNI: 0000 0004 0470 5454. GRID: grid.15444.30 Emergency Department, Groupe Hospitalier Pitié-Salpêtrière, Paris, France. ISNI: 0000 0001 2150 9058. GRID: grid.411439.a Morton Plant Hospital, Clearwater, USA. ISNI: 0000 0000 8602 0133. GRID: grid.416123.3 Department of Laboratory Medicine, Kantonsspital Aarau, Aarau, Switzerland. ISNI: 0000 0000 8704 3732. GRID: grid.413357.7 Royal Cornwall Hospital Trust, Truro, UK. ISNI: 0000 0004 0474 4488. GRID: grid.412944.e Manchester Royal Infirmary, Manchester, UK. ISNI: 0000 0004 0641 2823. GRID: grid.419319.7 University of Tsukuba, Tsukuba Medical Center Hospital, Tsukuba, Japan. ISNI: 0000 0004 1764 0856. GRID: grid.417324.7 Kent, Surrey & Sussex Air Ambulance Trust, Kent, UK Prometheus Delta-Tech, Herefordshire, UK Stavanger University Hospital, Stavanger, Norway. ISNI: 0000 0004 0627 2891. GRID: grid.412835.9 Aseer Central Hospital, Abha, Saudi Arabia. ISNI: 0000 0004 0607 7156. GRID: grid.413974.c HagaZiekenhuis, Den Haag, Netherlands. ISNI: 0000 0004 0568 6689. GRID: grid.413591.b Reinier de Graaf Gasthuis, Delft, Netherlands. ISNI: 0000 0004 0624 5690. GRID: grid.415868.6 Santa Maria University Hospital, Lisboa, Portugal. ISNI: 0000 0001 2295 9747. GRID: grid.411265.5 St. Vincent’s University Hospital, Dublin 4, Ireland. ISNI: 0000 0001 0315 8143. GRID: grid.412751.4 Percy Military Teaching Hospital, Clamart, France Whiston Hospital, Prescot, UK. ISNI: 0000 0004 0417 1894. GRID: grid.417083.9 King Abdulaziz Medical City, National Guard Hospital, Riyadh, Saudi Arabia. ISNI: 0000 0004 1790 7311. GRID: grid.415254.3 Department of Management, College of Business Administration, King Saud University, Saudi Arabia, Riyadh, Saudi Arabia. ISNI: 0000 0004 1773 5396. GRID: grid.56302.32 Ege University Hospital, Izmir, Turkey. ISNI: 0000 0004 0535 6364. GRID: grid.412190.f Katip Celebi University, Health Sciences Faculty, Izmir, Turkey Milton Keynes University Hospital NHS Foundation Trust, Milton Keynes, UK. GRID: grid.415667.7 Faculty of Pharmacy, Mahidol University, Bangkok, Thailand. ISNI: 0000 0004 1937 0490. GRID: grid.10223.32 Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. ISNI: 0000 0004 1937 0490. GRID: grid.10223.32 Specialist Anesthesia, Doha, Qatar University of Canterbury, Christchurch, New Zealand. ISNI: 0000 0001 2179 1970. GRID: grid.21006.35 Christchurch Hospital, Christchurch, New Zealand. ISNI: 0000 0004 0614 1349. GRID: grid.414299.3 Clinical Center Ljubljana, Ljubljana, Slovenia. ISNI: 0000 0004 0571 7705. GRID: grid.29524.38 The Royal Marsden Hospital, London, UK. ISNI: 0000 0004 0417 0461. GRID: grid.424926.f Bogomolets National Medical University, Kiev, Ukraine. GRID: grid.412081.e Royal Liverpool Intensive Care Unit, Liverpool, UK Homerton University Hospital, London, UK. GRID: grid.439591.3 University of Sao Paulo, Sao Paulo, Brazil. ISNI: 0000 0004 1937 0722. GRID: grid.11899.38 University of Leicester, Leicester, UK. ISNI: 0000 0004 1936 8411. GRID: grid.9918.9 Research and Education Institute, Sao Paulo, Brazil Ipswich Hospital NHS Trust, England, UK, Ipswich, UK. ISNI: 0000 0004 0413 7370. GRID: grid.412930.d Phramongkutklao Hospital, Bangkok, Thailand. ISNI: 0000 0004 0576 1212. GRID: grid.414965.b Phramongkutklao College of Medicine, Bangkok, Thailand. ISNI: 0000 0004 1937 0490. GRID: grid.10223.32 Pusan National University Hospital, Busan, South Korea. ISNI: 0000 0000 8611 7824. GRID: grid.412588.2 PICU, Hippokration General Hospital, Thessaloniki, Greece. ISNI: 0000 0004 0621 2899. GRID: grid.414122.0 King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia. ISNI: 0000 0001 2191 4301. GRID: grid.415310.2 The Jikei University School of Medicine, Tokyo, Japan. ISNI: 0000 0001 0661 2073. GRID: grid.411898.d PPG Internal Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. ISNI: 0000 0001 2294 473X. GRID: grid.8536.8 Hospital Esperanca Recife, Recife, Brazil Hospital Total Cor, Rio de Janeiro, Brazil Hospital viValle, São José dos Campos, Brazil Hospital Rios DOr, Rio de Janeiro, Brazil Hospital Norte DOr, Rio de Janeiro, Brazil Hospital Esperanca Olinda, Olinda, Brazil DOr Institute for Research and Education - IDOR, Rio de Janeiro, Brazil. GRID: grid.472984.4 Stamford Hospital, Stamford, USA. ISNI: 0000 0004 0377 0318. GRID: grid.416984.6 Darent Valley Hospital, Dartford, UK. ISNI: 0000 0004 0398 7314. GRID: grid.413475.0 St James’s University Hospital, Leeds, UK. GRID: grid.443984.6 Hospital Maciel, Montevideo, Uruguay. GRID: grid.414794.b Hospital de Cancer de Barretos, Barretos, Brazil. ISNI: 0000 0004 0615 7498. GRID: grid.427783.d Hospital Sírio Libanês, Sao Paulo, Brazil. ISNI: 0000 0000 9080 8521. GRID: grid.413471.4 Sta. Casa de Porto Alegre, Porto Alegre, Brazil University of Pittsburgh Medical Center, Pittsburgh, USA. ISNI: 0000 0001 0650 7433. GRID: grid.412689.0 Hospital Sao Lucas, Rio de Janeiro, Brazil Sheffield Teaching Hospitals, Sheffield, UK. GRID: grid.419135.b Instituto Português de Oncologia Francisco Gil - Porto, Porto, Portugal. ISNI: 0000 0004 0631 0608. GRID: grid.418711.a Hôpital Bichat, Paris, France. ISNI: 0000 0000 8588 831X. GRID: grid.411119.d Abertawe Bro Morgannwg University Health Board, Swansea, UK. ISNI: 0000 0000 8959 0182. GRID: grid.419728.1 Centro Hospitalar Porto, Porto, Portugal. ISNI: 0000 0004 0392 7039. GRID: grid.418340.a Apollo Speciality Hospital - OMR, Chennai, India. ISNI: 0000 0004 1802 3550. GRID: grid.413839.4 Kingston General Hospital, Kingston, Canada. ISNI: 0000 0004 0633 727X. GRID: grid.415354.2 Milton Keynes Hospital, Milton Keynes, UK. GRID: grid.415667.7 Imperial College, London, UK. ISNI: 0000 0001 2113 8111. GRID: grid.7445.2 Buckinghamshire Healthcare NHS Trust, Aylesbury, UK. ISNI: 0000 0004 0368 863X. GRID: grid.439664.a IPO -Porto, Porto, Portugal. GRID: grid.435544.7 KU Leuven, Leuven, Belgium. ISNI: 0000 0001 0668 7884. GRID: grid.5596.f Ernesto Dornelles Hospital, Porto Alegre, Brazil Gelre Ziekenhuizen, Apeldoorn, Netherlands. ISNI: 0000 0004 0370 4214. GRID: grid.415355.3 Surrey and Sussex NHS Trust, Redhill, UK Ege University School of Medicine, Izmir, Turkey. ISNI: 0000 0001 1092 2592. GRID: grid.8302.9 katip Celebi University, Izmir, Turkey. ISNI: 0000 0004 0454 9420. GRID: grid.411795.f Alexandria University Faculty of medicine, Alexandria, Egypt. ISNI: 0000 0001 2260 6941. GRID: grid.7155.6 Fortis Escorts Heart Institute, New Delhi, India. ISNI: 0000 0004 1804 7827. GRID: grid.417966.b FMRI, Gurgaon, India. ISNI: 0000 0004 4653 2037. GRID: grid.464839.4 Philips Research North America, Cambridge, USA. GRID: grid.417285.d Hospital Sao Rafael, Salvador, Brazil. GRID: grid.413466.2 Hospital das Clinicas, Sao Paulo, Brazil. ISNI: 0000 0001 2297 2036. GRID: grid.411074.7 St Helens and Knowsley, Liverpool, UK STH, Sheffield, UK Freeman Hospital, Newcastle upon Tyne, UK. ISNI: 0000 0004 0641 3308. GRID: grid.415050.5 Hospital Nove de Julho, Sao Paulo, Brazil University Hospital Coventry and Warwickshire, Coventry, UK. GRID: grid.15628.38 Sunnybrook Health Sciences Centre, Toronto, Canada. ISNI: 0000 0000 9743 1587. GRID: grid.413104.3 NHS Scotland, Glasgow, UK. ISNI: 0000 0000 9506 6213. GRID: grid.422655.2 Royal College of Surgeons of Ireland, Dublin, Ireland. ISNI: 0000 0004 0488 7120. GRID: grid.4912.e University Leiden, Leiden, Netherlands. ISNI: 0000 0001 2312 1970. GRID: grid.5132.5 Gelre Hospitals, Apeldoorn, Netherlands. ISNI: 0000 0004 0370 4214. GRID: grid.415355.3 VU University Amsterdam, Amsterdam, Netherlands. ISNI: 0000 0004 1754 9227. GRID: grid.12380.38 Hospital de Santo António, Oporto Hospital Center, Porto, Portugal Faculty of Psychology and Educational Sciences, Heerlen, Netherlands University of Toronto at Scarborough, Scarborough, ON Canada. ISNI: 0000 0001 2157 2938. GRID: grid.17063.33 University of Szeged, Szeged, Hungary. ISNI: 0000 0001 1016 9625. GRID: grid.9008.1 Jahn Ferenc Hospital, Budapest, Hungary University of Pécs, Pécs, Hungary. ISNI: 0000 0001 0663 9479. GRID: grid.9679.1 Hospital Clinico Universidad de Chile, Santiago, Chile. GRID: grid.412248.9 Royal Marsden Hospital, London, UK. ISNI: 0000 0004 0417 0461. GRID: grid.424926.f Centre Hospitalier de Lens, Lens, France. ISNI: 0000 0004 0642 1236. GRID: grid.470048.f Ntra Sra de Candelaria University Hospital, Santa Cruz de Tenerife, Spain University of Texas at Austin, San Antonio, USA. ISNI: 0000 0004 1936 9924. GRID: grid.89336.37 Beaumont Hospital, Dublin, Ireland. ISNI: 0000 0004 0617 6058. GRID: grid.414315.6 St Helens and Knowsley teaching hospitals, Liverpool, UK. GRID: grid.430747.3 Maastricht University Medical Center, Maastricht, Netherlands. GRID: grid.412966.e University Hospital Antwerp, Edegem, Belgium. ISNI: 0000 0004 0626 3418. GRID: grid.411414.5 University of Calgary, Calgary, Canada. ISNI: 0000 0004 1936 7697. GRID: grid.22072.35 Vrije Universiteit Brussel, Brussel, Belgium. ISNI: 0000 0001 2290 8069. GRID: grid.8767.e EMGO+/VU University medical center, Utrecht, Netherlands. ISNI: 0000000090126352. GRID: grid.7692.a Universitair Ziekenhuis Brussel, Brussel, Belgium. ISNI: 0000 0004 0626 3362. GRID: grid.411326.3 Lewisham & Greenwich NHS Trust, London, UK. GRID: grid.429537.e National Burn Unit, Montevideo, Uruguay St Elisabeth Ziekenhuis, Tilburg, Netherlands. GRID: grid.416373.4 Fondazione IRCCS Ca’ Granda - Ospedale maggiore Policlinico, Milan, Italy. ISNI: 0000 0004 1757 8749. GRID: grid.414818.0 Istituto per lo Studio e la Prevenzione Oncologica, Florence, Italy. ISNI: 0000 0004 1758 0566. GRID: grid.417623.5 AN - 27885969 AU - Bateman, R. M. AU - Sharpe, M. D. AU - Jagger, J. E. AU - Ellis, C. G. AU - Solé-Violán, J. AU - López-Rodríguez, M. AU - Herrera-Ramos, E. AU - Ruíz-Hernández, J. AU - Borderías, L. AU - Horcajada, J. AU - González-Quevedo, N. AU - Rajas, O. AU - Briones, M. AU - Rodríguez de Castro, F. AU - Rodríguez Gallego, C. AU - Esen, F. AU - Orhun, G. AU - Ergin Ozcan, P. AU - Senturk, E. AU - Ugur Yilmaz, C. AU - Orhan, N. AU - Arican, N. AU - Kaya, M. AU - Kucukerden, M. AU - Giris, M. AU - Akcan, U. AU - Bilgic Gazioglu, S. AU - Tuzun, E. AU - Riff, R. AU - Naamani, O. AU - Douvdevani, A. AU - Takegawa, R. 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AU - Enguix-Armada, A. AU - Puerto-Morlan, A. AU - Perez-Valero, V. AU - Garcia-Alcantara, A. AU - Bolton, N. AU - Dudziak, J. AU - Bonney, S. AU - Tridente, A. AU - Nee, P. AU - Nicolaes, G. AU - Wiewel, M. AU - Schultz, M. AU - Wildhagen, K. AU - Horn, J. AU - Schrijver, R. AU - Van der Poll, T. AU - Reutelingsperger, C. AU - Pillai, S. AU - Davies, G. AU - Mills, G. AU - Aubrey, R. AU - Morris, K. AU - Williams, P. AU - Evans, P. AU - Gayat, E. G. AU - Struck, J. AU - Cariou, A. AU - Deye, N. AU - Guidet, B. AU - Jabert, S. AU - Launay, J. AU - Legrand, M. AU - Léone, M. AU - Resche-Rigon, M. AU - Vicaut, E. AU - Vieillard-Baron, A. AU - Mebazaa, A. AU - Arnold, R. AU - Capan, M. AU - Linder, A. AU - Akesson, P. AU - Popescu, M. AU - Tomescu, D. AU - Sprung, C. L. AU - Calderon Morales, R. AU - Munteanu, G. AU - Orenbuch-Harroch, E. AU - Levin, P. AU - Kasdan, H. AU - Reiter, A. AU - Volker, T. AU - Himmel, Y. AU - Cohen, Y. AU - Meissonnier, J. AU - Girard, L. AU - Rebeaud, F. 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Carvalho, C Velasco, I Kelly, J M Neill, A Rubenfeld, G Masson, N Min, A Boezeman, E Hofhuis, J Hovingh, A De Vries, R Cabral-Campello, G Van Mol, M Nijkamp, M Kompanje, E Ostrowski, P Kiss, K Köves, B Csernus, V Molnár, Z Hoydonckx, Y Vanwing, S Medo, V Galvez, R Miranda, J P Stone, C Wigmore, T Arunan, Y Wheeler, A Wong, Y Poi, C Gu, C Molmy, P Van Grunderbeeck, N Nigeon, O Lemyze, M Thevenin, D Mallat, J Correa, M Carvalho, R T Fernandez, A McBride, C Koonthalloor, E Walsh, C Webber, A Ashe, M Smith, K Dimitriadou, M Mantzafleri, P Vrani, O Arbouti, A Varsami, T Bollen, J A Van Smaalen, T C De Jongh, W C Ten Hoopen, M M Ysebaert, D Van Heurn, L W Van Mook, W N Roze des Ordons, A Couillard, P Doig, C Van Keer, R V Deschepper, R D Francke, A F Huyghens, L H Bilsen, J B Nyamaizi, B Dalrymple, C Dobru, A Marrinan, E Ankuli, A Struthers, R Crawford, R Morelli, P Degiovanangelo, M Lemos, F MArtinez, V Cabrera, J Rutten, A Van Ieperen, S De Geer, S Van Vugt, M Der Kinderen, E Giannini, A Miccinesi, G Marchesi, T Prandi, E Congress Overall Crit Care. 2016 Apr 20;20(Suppl 2):94. doi: 10.1186/s13054-016-1208-6. PY - 2016 SN - 1364-8535 (Print) 1364-8535 SP - 94 ST - 36th International Symposium on Intensive Care and Emergency Medicine : Brussels, Belgium. 15-18 March 2016 T2 - Crit Care TI - 36th International Symposium on Intensive Care and Emergency Medicine : Brussels, Belgium. 15-18 March 2016 VL - 20 ID - 3980 ER - TY - JOUR AB - A case is presented of a transitional lumbosacral vertebra in a adolescent girl, presenting with low back pain. There was no evidence of a pars interarticularis defect. Careful assessment of children or adolescents presenting with low back pain is important since back pain in this age group is usually caused by organic disease. AU - Batt, M. E. AU - Skattum, N. AU - Chong, B. K. AU - Tanji, J. L. DA - 1996/12// DO - 10.1136/bjsm.30.4.356 DP - PubMed IS - 4 J2 - Br J Sports Med KW - Adolescent Female Gymnastics Humans Low Back Pain Lumbar Vertebrae Pseudarthrosis Radiography Radionuclide Imaging Spinal Fractures LA - eng PY - 1996 SN - 0306-3674 SP - 356-358 ST - Posterior element pain in a adolescent schoolgirl T2 - British Journal of Sports Medicine TI - Posterior element pain in a adolescent schoolgirl UR - http://www.ncbi.nlm.nih.gov/pubmed/9091138 VL - 30 ID - 129 ER - TY - JOUR AB - ObjectivesTo analyze the relation between the symptoms reported by adolescents with chronic tension-type headache (CTTH) and their perception of their emotional and behavioral functioning.MethodsTwo groups of adolescents (clinical group, n 48; control group, n 135) and their parents (clinical group, n 42; control group, n 128) were studied, respectively, with the Youth Self-Report Questionnaire and the Child Behavior Checklist. Moreover, a secondary analysis was performed, identifying another subgroup of adolescents who reported having headaches.ResultsThe clinical group of adolescents obtained higher scores than the control group in Internalizing Syndrome; Aggressive Behavior for Externalizing Syndrome; Social, Thought, and Attention Problems; and in all Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV)-oriented scales (except conduct problems). Differences between the two groups of parents were found in all the scales. The controls reporting headaches obtained interesting intermediate scores.ConclusionsAdolescents with CTTH show greater emotional and behavioral problems than their healthy peers. Consequently, clinical approaches for proper diagnosis and treatment need to adopt a multidisciplinary prospective. AN - WOS:000268331400002 AU - Battistutta, S. AU - Aliverti, R. AU - Montico, M. AU - Zin, R. AU - Carrozzi, M. DA - Aug DO - 10.1093/jpepsy/jsn102 IS - 7 N1 - Battistutta, Sara Aliverti, Renata Montico, Marcella Zin, Roberto Carrozzi, Marco Montico, Marcella/B-5290-2013 Montico, Marcella/0000-0003-0377-8232; Carrozzi, Marco/0000-0001-6282-4417 1465-735x PY - 2009 SN - 0146-8693 SP - 697-706 ST - Chronic Tension-Type Headache in Adolescents. Clinical and Psychological Characteristics Analyzed Through Self- and Parent-Report Questionnaires T2 - Journal of Pediatric Psychology TI - Chronic Tension-Type Headache in Adolescents. Clinical and Psychological Characteristics Analyzed Through Self- and Parent-Report Questionnaires UR - ://WOS:000268331400002 VL - 34 ID - 2597 ER - TY - JOUR AB - Introduction: Complex regional pain syndrome type 1 (CRPS I) in children differs from its adult counterpart and relevant literature is scarce. Our aim was to investigate potential risk factors and to assess midterm outcome and quality of life. Material and methods: Medical records of patients diagnosed with CRPS I between 2004 and 2012 were analyzed. Patients and parents were called for a phone interview including the PEDS Quality of Life 4-0 questionnaire. Results were compared to a control group matched for age, gender and socio-economic status. Results: Seventy-three patients were included (64 girls, 9 boys). Mean age at diagnosis was 11.5 years and mean time to diagnosis was 14.2 months. The lower limb was affected in 89% of cases. Allodynia, coldness and cyanosis were noted in 95%, 81% and of 74% of cases, respectively. Forty-nine percent of patients reported a physical injury. Multivariate analysis showed a strong association with being anxious (OR = 44.9, 95% CI [7.4-273]), presence of an atopic background (OR = 25.0, 95% CI: [4.6-135]), being good to excellent school performers (OR = 8.4 95% CI [1.3-52.1]), and having trouble falling asleep (OR = 5.3,95% CI [1.6-17.0]). At a mean 37 months' follow-up (12-102), PEDS QL 4-0 score was significantly lower in CRPS patients compared to controls. Fifty-seven percent of patients acknowledged healing and 55% had presented a relapse. Conclusion: Childhood onset CRPS I affects predominantly preadolescent girls at the ankle. The present study highlights the relatively poor outcome, especially its physical and emotional aspects and the large role of psychology. (C) 2015 Elsevier Masson SAS. All rights reserved. AN - WOS:000362985500017 AU - Bayle-Iniguez, X. AU - Audouin-Pajot, C. AU - de Gauzy, J. S. AU - Munzer, C. AU - Murgier, J. AU - Accadbled, F. DA - Oct DO - 10.1016/j.otsr.2015.06.013 IS - 6 N1 - Bayle-Iniguez, X. Audouin-Pajot, C. de Gauzy, J. Sales Munzer, C. Murgier, J. Accadbled, F. murgier, jerome/U-7387-2019 murgier, jerome/0000-0002-9237-1372 PY - 2015 SN - 1877-0568 SP - 745-748 ST - Complex regional pain syndrome type I in children. Clinical description and quality of life T2 - Orthopaedics & Traumatology-Surgery & Research TI - Complex regional pain syndrome type I in children. Clinical description and quality of life UR - ://WOS:000362985500017 VL - 101 ID - 2218 ER - TY - JOUR AB - Functional abdominal pain (FAP) is a common physical complaint in children and adolescents. Prior research has documented associations between FAP symptoms and mood, especially internalizing behaviors. Limited research is available examining the association between symptom burden and cognitive function in this pediatric population. This study explored associations between FAP symptoms, internalizing behaviors, and cognitive and school function in children and adolescents. Twenty-seven participants (mean age = 12.6 years, range 8.8-16.5; 33% male) diagnosed with FAP completed assessments of cognitive, emotional, and behavioral function, as well as FAP symptom severity. Mean performances on cognitive tests were within age-expected ranges. Within this context, however, higher overall burden of FAP symptoms was associated with slower processing speed, more self-reported metacognitive problems and internalizing behaviors, and more school absences. Cognitive function was systematically associated with internalizing behaviors but not physical symptoms. Overall, findings revealed that FAP may be associated with cognitive inefficiencies in addition to internalizing problems. Cognitive symptoms may be linked to internalizing behaviors associated with FAP. AN - WOS:000545795800001 AU - Bearden, D. J. AU - Waber, D. P. AU - Schreiber, J. E. AU - Mrakotsky, C. DO - 10.1080/21622965.2020.1758106 N1 - Bearden, Donald J. Waber, Deborah P. Schreiber, Jane E. Mrakotsky, Christine 2162-2973 SN - 2162-2965 ST - Functional abdominal pain symptom severity: Associations between cognition and emotion in a pediatric sample T2 - Applied Neuropsychology-Child TI - Functional abdominal pain symptom severity: Associations between cognition and emotion in a pediatric sample UR - ://WOS:000545795800001 ID - 1814 ER - TY - JOUR AB - Objective To provide a new approach for conceptualizing and studying functional somatic symptoms (FSS) in children and adolescence. Methods A developmental model is proposed based on the synthesis of the extant literature and previous theoretical perspectives of FSS in children and adolescents. Results Multiple risk and protective factors from child, familial, social, and environmental domains, the interactions across risk domains, and potential developmental pathways of FSS are identified. Conclusions This article underscores the necessity of taking a broader, developmental view of FSS. The tenets of developmental psychopathology emphasize the utility of viewing FSS on a continuum of severity rather than as a discrete entity or diagnosis. This article concludes with directions for future research and treatment implications. AN - WOS:000255757700009 AU - Beck, J. E. DA - Jun DO - 10.1093/jpepsy/jsm113 IS - 5 N1 - Beck, Joy E. 1465-735x PY - 2008 SN - 0146-8693 SP - 547-562 ST - A developmental perspective on functional somatic symptoms T2 - Journal of Pediatric Psychology TI - A developmental perspective on functional somatic symptoms UR - ://WOS:000255757700009 VL - 33 ID - 2649 ER - TY - JOUR AB - BACKGROUND: Although vocational rehabilitation is a widely advocated intervention for workers on sick leave due to subacute or chronic nonspecific musculoskeletal pain, the optimal dosage of effective and cost-effective vocational rehabilitation remains unknown. The objective of this paper is to describe the design of a non-inferiority trial evaluating the effectiveness and cost-effectiveness of 40-h multidisciplinary vocational rehabilitation compared with 100-h multidisciplinary vocational rehabilitation on work participation for workers on sick leave due to subacute or chronic musculoskeletal pain. METHODS/DESIGN: A non-inferiority study design will be applied. The study population consists of workers who are on part-time or full-time sick leave due to subacute or chronic nonspecific musculoskeletal pain. Two multidisciplinary vocational rehabilitation programs following the bio-psychosocial approach will be evaluated in this study: 40-h vocational rehabilitation and 100-h vocational rehabilitation, both delivered over a maximum of 15 weeks. The 100-h vocational rehabilitation comprises five modules: work participation coordination, graded activity, cognitive behavioral therapy, group education, and relaxation. The 40-h vocational rehabilitation comprises work participation coordination and a well-reasoned choice from the other four modules. Four rehabilitation centers will participate in this study, each delivering both interventions. Patients will be randomized into one of the interventions, stratified for the duration of sick leave (<6 weeks or ≥ 6 weeks) and type of sick leave (part-time or full-time). The primary outcome is work participation, measured by self-reported sick leave days, and will be assessed at baseline, mid-term, discharge, and at 2, 4, 6, 8, 10, and 12 months follow-up. Secondary outcomes are work ability, disability, quality of life, and physical functioning and will be assessed at baseline, discharge, and at 6 and 12 months follow-up. Cost outcomes are absenteeism, presenteeism, healthcare usage, and travelling costs. Cost-effectiveness will be evaluated from the societal and employer perspectives. DISCUSSION: The results obtained from this study will be useful for vocational rehabilitation practice and will provide stakeholders with relevant insights into two versions of vocational rehabilitation. TRIAL REGISTRATION: Dutch Trial Register identifier: NTR4362 (registered 17 March 2014). AD - Department of Rehabilitation Medicine, Center for Rehabilitation, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. t.beemster@amc.uva.nl. Department of Research and Development, Heliomare Rehabilitation Center, Wijk aan Zee, The Netherlands. t.beemster@amc.uva.nl. Coronel Institute of Occupational Health, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. t.beemster@amc.uva.nl. Department of Research and Development, Heliomare Rehabilitation Center, Wijk aan Zee, The Netherlands. j.van.velzen@heliomare.nl. Coronel Institute of Occupational Health, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. j.van.velzen@heliomare.nl. Department of Research and Development, Heliomare Rehabilitation Center, Wijk aan Zee, The Netherlands. c.van.bennekom@heliomare.nl. Coronel Institute of Occupational Health, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. c.van.bennekom@heliomare.nl. Coronel Institute of Occupational Health, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. m.frings@uva.amc.nl. Department of Rehabilitation Medicine, Center for Rehabilitation, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. m.f.reneman@cvr.umcg.nl. AN - 26215748 AU - Beemster, T. T. AU - van Velzen, J. M. AU - van Bennekom, C. A. AU - Frings-Dresen, M. H. AU - Reneman, M. F. C2 - PMC4518875 DA - Jul 28 DO - 10.1186/s13063-015-0861-4 DP - NLM ET - 2015/07/29 KW - Absenteeism Adolescent Adult Aged Chronic Pain/diagnosis/*economics/physiopathology/psychology/*rehabilitation Cognitive Behavioral Therapy/economics Cost-Benefit Analysis Female Group Processes *Health Care Costs Humans Male Middle Aged Musculoskeletal Pain/diagnosis/*economics/physiopathology/psychology/*rehabilitation Netherlands Occupational Health/*economics Patient Education as Topic/economics Rehabilitation, Vocational/*economics/methods Relaxation Therapy/economics Research Design Return to Work/*economics Sick Leave/*economics Time Factors Treatment Outcome Young Adult LA - eng N1 - 1745-6215 Beemster, Timo T van Velzen, Judith M van Bennekom, Coen A M Frings-Dresen, Monique H W Reneman, Michiel F Comparative Study Journal Article Multicenter Study Randomized Controlled Trial Research Support, Non-U.S. Gov't Trials. 2015 Jul 28;16:317. doi: 10.1186/s13063-015-0861-4. PY - 2015 SN - 1745-6215 SP - 317 ST - Cost-effectiveness of 40-hour versus 100-hour vocational rehabilitation on work participation for workers on sick leave due to subacute or chronic musculoskeletal pain: study protocol for a randomized controlled trial T2 - Trials TI - Cost-effectiveness of 40-hour versus 100-hour vocational rehabilitation on work participation for workers on sick leave due to subacute or chronic musculoskeletal pain: study protocol for a randomized controlled trial VL - 16 ID - 3235 ER - TY - JOUR AB - BACKGROUND/AIMS:  Ventriculoperitoneal shunts (VPS) are a mainstay of treatment for hydrocephalus. Morbidity related to infection and dysfunction is well known, whereas data on psychosocial outcome and quality of life are scarce. Our aim was to assess headache burden and shunt-related impact on daily life in children growing up with a VPS. METHODS:  Patients between 3 and 21 years of age were identified and their families were contacted. A set of standardized questionnaires was used to assess headache and quality of life. RESULTS:  Fifteen patients with a mean age of 12 years agreed to participate in this study. Satisfaction with the VPS and improvement of the patient's condition was reported by 87%. A total of 67% denied negative impact on everyday life, reported a headache less than once a month, and never or rarely miss school. However, 53% take precautions before special activities. CONCLUSIONS:  The results demonstrate that modern VPS systems are tolerated very well and do not per se reduce quality of life. However, patients adapt to the presence of a VPS by avoiding risks and taking precautions. Chronic headache is not a major problem and not necessarily attributed to the VPS. Nevertheless, most patients asked for technical improvements, which might guide future research and the technical development of VPS. AD - Department of Neurosurgery, Medical Faculty, Heinrich-Heine-Universität, Düsseldorf, Germany. AN - 28962065 AU - Beez, T. AU - Bellstädt, L. AU - Steiger, H. J. AU - Sarikaya-Seiwert, S. DA - May DO - 10.1055/s-0037-1606852 DP - NLM ET - 2017/09/30 IS - 3 KW - *Activities of Daily Living Adolescent Child Child, Preschool Female Headache/*etiology Humans Hydrocephalus/*surgery Male Quality of Life Treatment Outcome Ventriculoperitoneal Shunt/*adverse effects Young Adult LA - eng N1 - 2193-6323 Beez, Thomas Bellstädt, Lina Steiger, Hans-Jakob Sarikaya-Seiwert, Sevgi Journal Article Germany J Neurol Surg A Cent Eur Neurosurg. 2018 May;79(3):196-199. doi: 10.1055/s-0037-1606852. Epub 2017 Sep 29. PY - 2018 SN - 2193-6315 SP - 196-199 ST - Headache and Shunt-Related Impact on Activities of Daily Life in Patients Growing Up with a Ventriculoperitoneal Shunt T2 - J Neurol Surg A Cent Eur Neurosurg TI - Headache and Shunt-Related Impact on Activities of Daily Life in Patients Growing Up with a Ventriculoperitoneal Shunt VL - 79 ID - 3907 ER - TY - JOUR AB - Low back pain (LBP) in children was considered for many years to be a rare condition revealing a serious disease, but in the last two decades, epidemiological studies have shown that the prevalence of nonspecific LBP in children is high. This study was aimed at analyzing the prevalence, severity, consequences and associated factors of LBP in children. A cross-sectional study was undertaken in two preparatory schools in the city of Monastir, Tunisia, in April 2002. This study included a total of 622 children and adolescents--326 females and 296 males--with a mean age of 14 years (range: 11-19 years). They completed the questionnaire in the presence of the physician. For the first 201 questionnaires collected, the corresponding children and adolescents underwent a spine medical examination, with evaluation of pain by visual analog scale if LBP was present. A stepwise logistic regression analysis was carried out to determine the risk factors associated with LBP and chronic LBP. The cumulative lifetime prevalence of LBP was 28.4%. Eight percent of the subjects suffered from chronic LBP. LBP was responsible for 23% of school absenteeism and 29% for sports absenteeism. Medical care requirement was observed in 32.2% and psychological symptoms in 75%. Stepwise logistic regression analysis showed that three factors were associated with LBP: school failure (held back 1 year), odds ratio (OR) =2.6 (95% confidence interval [CI], 1.96-3.44), family history of LBP (parental or sibling LBP), OR=3.80 (95% CI, 2.94-5.92), dissatisfaction with school chair (in height and comfort), OR=3.40 (95% CI, 2.24-5.29). Two factors were associated with chronic LBP: dissatisfaction with school chair, OR=1.62 (95% CI, 1.46-3.32) and football playing, OR=3.07 (95% CI, 2.15-5.10). The prevalence of LBP among Tunisian schoolchildren and adolescents is high. This requires preventive measures and longitudinal studies, which are very important from the standpoint of public health. AU - Bejia, Ismail AU - Abid, Nabiha AU - Ben Salem, Kamel AU - Letaief, Mondher AU - Younes, Mohamed AU - Touzi, Mongi AU - Bergaoui, Naceur DA - 2005/05// DO - 10.1007/s00586-004-0785-2 DP - PubMed IS - 4 J2 - Eur Spine J KW - Absenteeism Adolescent Child Cohort Studies Cross-Sectional Studies Delivery of Health Care Female Humans Low Back Pain Male Mental Health Pain Posture Prevalence Severity of Illness Index Tunisia LA - eng PY - 2005 SN - 0940-6719 SP - 331-336 ST - Low back pain in a cohort of 622 Tunisian schoolchildren and adolescents T2 - European Spine Journal: Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society TI - Low back pain in a cohort of 622 Tunisian schoolchildren and adolescents: an epidemiological study UR - http://www.ncbi.nlm.nih.gov/pubmed/15940479 VL - 14 ID - 111 ER - TY - JOUR AB - OBJECTIVES: The objective of this article is to determine the relationship between headache frequency and socio-demographic data, personal characteristics, habits, daily activities, daily loss of ability, depression and anxiety in the headache subtypes in the pediatric population. PATIENTS AND METHODS: Our sample group was composed of approximately 5355 children aged between 9 and 18 years. An eight-stage questionnaire was administered to the children. In the second stage of the study, headache subtypes were created according to the ICHD-II criteria. The resulting data were compared according to the results of the headache subtypes. RESULTS: In school-age children, the prevalence of recurrent headaches was 39.4%, and the prevalence of migraine was 10.3%. The subjects with migraine mostly preferred sedentary activities in their leisure time, and preferred less exercise than the subjects with the other headache types. The PedMIDAS score of the children who preferred to play sports was significantly lower than those who did not prefer to play sports. In the group that preferred reading books, an opposite relationship was found. In overweight and obese migraine sufferers, other types of headache were found to be significantly higher. CONCLUSIONS: In the management of treating childhood headaches, the association of psychiatric comorbidities should be considered. To minimize disability, children should be directed to more useful physical activities. AD - Department of Pediatric Neurology, Ankara University Medical School, Turkey bektasomer@gmail.com. Department of Child and Adolescent Psychiatry, Ankara University Medical School, Turkey. Department of Statistics, Ankara University Medical School, Turkey. Department of Pediatric Neurology, Ankara University Medical School, Turkey. AN - 25149505 AU - Bektaş, Ö AU - Uğur, C. AU - Gençtürk, Z. B. AU - Aysev, A. AU - Sireli, Ö AU - Deda, G. DA - May DO - 10.1177/0333102414547134 DP - NLM ET - 2014/08/26 IS - 6 KW - Adolescent Anxiety/psychology Child Cross-Sectional Studies Depression/psychology Feeding Behavior/psychology Female Headache/*epidemiology/*psychology Humans Leisure Activities/*psychology Male Prevalence Surveys and Questionnaires Turkey/epidemiology PedMIDAS Pediatric headache anxiety depression habits leisure time LA - eng N1 - 1468-2982 Bektaş, Ömer Uğur, Cağatay Gençtürk, Zeynep Bıyıklı Aysev, Ayla Sireli, Özlem Deda, Gülhis Journal Article England Cephalalgia. 2015 May;35(6):527-37. doi: 10.1177/0333102414547134. Epub 2014 Aug 22. PY - 2015 SN - 0333-1024 SP - 527-37 ST - Relationship of childhood headaches with preferences in leisure time activities, depression, anxiety and eating habits: A population-based, cross-sectional study T2 - Cephalalgia TI - Relationship of childhood headaches with preferences in leisure time activities, depression, anxiety and eating habits: A population-based, cross-sectional study VL - 35 ID - 3899 ER - TY - JOUR AB - Background Thirty percent of children with acute otitis media (AOM) experience symptoms < 7 days after initiating treatment, highlighting the importance of comprehensive discharge instructions. Methods We randomized caregivers of children 6 months to 17 years presenting to the emergency department (ED) with AOM to discharge instructions using a video on management of pain and fever to a paper handout. The primary outcome was the AOM Severity of Symptom (AOM-SOS) score at 72 hours postdischarge. Secondary outcomes included caregiver knowledge (10-item survey), absenteeism, recidivism, and satisfaction (5-item Likert scale). Results A total of 219 caregivers were randomized and 149 completed the 72-hour follow-up (72 paper and 77 video). The median (IQR) AOM-SOS score for the video was significantly lower than paper, even after adjusting for preintervention AOM-SOS score and medication at home (8 [7-11] vs. 10 [7-13], respectively; p = 0.004). There were no significant differences between video and paper in mean (+/- SD) knowledge score (9.2 [+/- 1.3] vs. 8.8 [+/- 1.8], respectively; p = 0.07), mean (+/- SD) number of children that returned to a health care provider (8/77 vs. 10/72, respectively; p = 0.49), mean (+/- SD) number of daycare/school days missed by child (1.2 [+/- 1.5] vs. 1.1 [+/- 2.1], respectively; p = 0.62), mean (+/- SD) number of workdays missed by caregiver (0.5 [+/- 1] vs. 0.8 [+/- 2], respectively; p = 0.05), or median (IQR) satisfaction score (5 [4-5] vs. 5 [4-5], respectively; p = 0.3). Conclusions Video discharge instructions in the ED are associated with less perceived AOM symptomatology compared to a paper handout. AN - WOS:000497067900001 AU - Belisle, S. AU - Dobrin, A. AU - Elsie, S. AU - Ali, S. AU - Brahmbhatt, S. AU - Kumar, K. AU - Jasani, H. AU - Miller, M. AU - Ferlisi, F. AU - Poonai, N. DO - 10.1111/acem.13839 N1 - Belisle, Sheena Dobrin, Andrei Elsie, Sharlene Ali, Samina Brahmbhatt, Shaily Kumar, Kriti Jasani, Hardika Miller, Michael Ferlisi, Frank Poonai, Naveen Ali, Samina/0000-0002-0595-364X 1553-2712 SN - 1069-6563 ST - Video Discharge Instructions for Acute Otitis Media in Children: A Randomized Controlled Open-label Trial T2 - Academic Emergency Medicine TI - Video Discharge Instructions for Acute Otitis Media in Children: A Randomized Controlled Open-label Trial UR - ://WOS:000497067900001 ID - 1872 ER - TY - JOUR AB - Introduction Headaches is a public health problem. Objective To assess the epidemiological and clinical features of headaches and their impact on the quality of life in schoolboys. Patients and Method It was a prospective study made in protestant college of Lome - Tokoin from September, 2007 to September, 2008, on 171 students. Results The average age was 14.56 +/- 2.45 years old, with 49.12% (84) of male and female in 50.88%(87). The primary headaches global prevalence was 84.62% (71) in boys and 86.15% (75) in girls. The tension headaches were founded in 41.52% followed by the migraine (39.77%) and symptomatic headaches (6.43%) on IHS criteria. The school bad performance was noted in 40.35%. An important and major repercussion of headaches on daily life was observed with respectively 9.36% and 33.92% on HIT-6 test. Three and IV degrees of handicap were noted with respectively 15.20% and 9.36% on MIDAS test. Conclusion Headaches is present in schoolboys with negative impact on their quality of life. A real care of headaches can help to improve school success. AN - WOS:000422487600004 AU - Belo, M. AU - Assogba, K. AU - Awidina-Ama, A. AU - Guinhouya, K. AU - Apetse, K. AU - Kombate, D. AU - Kumako, V. AU - Banakinao, Y. AU - Balogou, A. A. K. AU - Grunitzky, E. G. IS - 2 N1 - Belo, Mofou Assogba, Komi Awidina-Ama, Awissoba Guinhouya, Kokou Apetse, Kossi Kombate, Damelan Kumako, Vinyo Banakinao, Yao Balogou, Agnon Ayelola Koffi Grunitzky, Eric G. 1992-2647 PY - 2009 SN - 1015-8618 SP - 29-34 ST - HEADACHE AND QUALITY OF LIFE IN SCHOOLBOYS AT LOME, TOGO T2 - African Journal of Neurological Sciences TI - HEADACHE AND QUALITY OF LIFE IN SCHOOLBOYS AT LOME, TOGO UR - ://WOS:000422487600004 VL - 28 ID - 2620 ER - TY - JOUR AB - Dental caries is a common chronic disease that causes pain and disability across all age groups. If left untreated, dental caries can lead to pain and infection, tooth loss, and edentulism (total tooth loss). Dental sealants are effective in preventing dental caries in the occlusal (chewing) and other pitted and fissured surfaces of the teeth. Enamel fluorosis is a hypomineralization of enamel related to fluoride exposure during tooth formation (first 6 years for most permanent teeth). Exposure to fluoride throughout life is effective in preventing dental caries. This is the first CDC Surveillance Summary that addresses these conditions and practices. 1988-1994 and 1999-2002. The National Health and Nutrition Examination Survey (NHANES) is an ongoing survey of representative samples of the civilian, noninstitutionalized U.S. population aged >/=2 months in NHANES 1988-1994 and all ages during 1999-2002. The dental component gathered information on persons aged >/=2 years. During 1999-2002, among children aged 2-11 years, 41% had dental caries in their primary teeth. Forty-two percent of children and adolescents aged 6-19 years and approximately 90% of adults had dental caries in their permanent teeth. Among children aged 6-19 years, 32% had received dental sealants. Adults aged >/=20 years retained a mean of 24 of 28 natural teeth and 8% were edentulous. Among persons aged 6-39 years, 23% had very mild or greater enamel fluorosis. Disparities were noticed across all age groups, among racial/ethnic groups, persons with lower education and income, and by smoking status. From 1988-1994 to 1999-2002, four trends were observed: 1) no change in the prevalence of dental caries in primary teeth among children aged 2-11 years, 2) a reduction in prevalence of caries in permanent teeth of up to 10 percentage points among persons aged 6-19 years and up to six percentage points among dentate adults aged >/=20 years, 3) an increase of 13 percentage points in dental sealants among persons aged 6-19 years, and 4) a six percentage point reduction in total tooth loss (edentulism) among persons aged >/=60 years. The findings of this report indicate that the dental caries status of permanent teeth has improved since the 1988-1994 survey. Despite the decrease in caries prevalence and severity in the permanent dentition and the increase in the proportion of children and adolescents who benefit from dental sealants, disparities remain. These data provide information for public health professionals in designing interventions to improve oral health and to reduce disparities in oral health, for researchers in assessing factors associated with disparities and dental caries in primary teeth, and in designing timely surveillance tools to monitor total fluoride exposure. AU - Beltrán-Aguilar, Eugenio AU - Barker, Laurie AU - Canto, María AU - Dye, Bruce AU - Gooch, Barbara AU - Griffin, Susan AU - Hyman, Jeffrey AU - Jaramillo, Freder AU - Kingman, Albert AU - Nowjack-Raymer, Ruth AU - Selwitz, Robert AU - Wu, Tianxia DA - 2005/09/01/ DP - ResearchGate J2 - Morbidity and mortality weekly report. Surveillance summaries (Washington, D.C. : 2002) PY - 2005 SP - 1-43 ST - Surveillance for dental caries, dental sealants, tooth retention, edentulism, and enamel fluorosis—United States, 1988-1994 and 1999-2002 T2 - Morbidity and mortality weekly report. Surveillance summaries (Washington, D.C. : 2002) TI - Surveillance for dental caries, dental sealants, tooth retention, edentulism, and enamel fluorosis—United States, 1988-1994 and 1999-2002 VL - 54 ID - 2 ER - TY - JOUR AB - Background: Musculoskeletal pain (MSP) is a public health problem among school-adolescents. This study aimed to identify the prevalence, risk factors and consequences of neck, shoulders and low-back pain among school-adolescents. Study design: A cross-sectional study. Methods: School-adolescents aged from 12 to 18 years between October 2017 and February 2018 in South of Tunisia were recruited. Eligible participants were randomly selected and were asked to respond a four-section questionnaire. Factors independently associated with MSP were determined through multivariate logistic regression analysis. Results: Among 1221 enrolled subjects, shoulders, low-back and neck pain were reported in 43%, 35.8% and 32%, respectively. Multivariate analysis showed that independent risk factors of neck pain were female gender (Adjusted odds ratio AOR=1.55; P=0.002), using computer >= 4 hours/week (AOR=1.50; P=0.010), too low desk (AOR=2.30; P<0.001) and carrying schoolbag >= 60 minutes (AOR=1.58; P=0.008). Female gender (AOR=3.30; P<0.001), BMI >= 25 Kg/m(2) (AOR=1.6; P=0.018), playing videogames >= 2 hours/day (AOR=2.37; P<0.001) and schoolbag to body weight >= 10% (AOR=1.46; P=0.026) were independently associated with shoulders pain. For low back-pain, independent risk factors were high-school grade (AOR=2.70; P<0.001), playing videogames >= 2 hours/day (AOR=1.83; P<0.001), watching TV >= 12 hours/week (AOR=1.5; P=0.016), too low seat backrest (AOR=1.4; P=0.005) and too far seat-to-black (board) distance (AOR=1.5; P=0.041). School-adolescents consumed drugs for MSP in 19.5%, had sleep disturbance in 34% and aggressive behaviors in 22.8%. Conclusions: The prevalence of MSP was substantially high among school-adolescents and their associated risk factors included sociodemographic factors, leisure activities and classroom furniture. An ergonomic specific and behavior-based school program is urgently needed. AN - WOS:000467371000007 AU - Ben Ayed, H. AU - Yaich, S. AU - Trigui, M. AU - Ben Hmida, M. AU - Ben Jemaa, M. AU - Ammar, A. AU - Jedidi, J. AU - Karray, R. AU - Feki, H. AU - Mejdoub, Y. AU - Kassis, M. AU - Damak, J. C7 - e00440 DA - Win DO - 10.15171/jrhs.2019.07 IS - 1 N1 - Ben Ayed, Houda Yaich, Sourour Trigui, Maroua Ben Hmida, Mariem Ben Jemaa, Maissa Ammar, Achraf Jedidi, Jihene Karray, Raouf Feki, Habib Mejdoub, Yosra Kassis, Mondher Damak, Jamel Ammar, Achraf/B-8455-2018 Ammar, Achraf/0000-0003-0347-8053 2228-7809 PY - 2019 SN - 2228-7795 ST - Prevalence, Risk Factors and Outcomes of Neck, Shoulders and Low-Back Pain in Secondary-School Children T2 - Journal of Research in Health Sciences TI - Prevalence, Risk Factors and Outcomes of Neck, Shoulders and Low-Back Pain in Secondary-School Children UR - ://WOS:000467371000007 VL - 19 ID - 1871 ER - TY - JOUR AB - In a randomized, blinded study, we compared the outcome from a full-time functional restoration program with the outcome from shorter active rehabilitation programs for patients with chronic, disabling low back pain. The study initially included 132 patients, randomized into one of three treatment programs: (1) an intensive 3-week multidisciplinary program; (2) active physical training and back school; or (3) psychological pain management and active physical training. Nine of the randomized patients never started in any program, so the studied population consisted of 123 patients. Of these, 14 patients (11%) dropped out. The results presented here are at 1 year following treatment, where we achieved a 92% response rate, including the drop-outs. The functional restoration program was superior to the shorter programs as to work-ready rate, health care contacts, back pain level, disability level, staying physically active, and reduction in analgesics. There was no significant difference between Programs 2 and 3 in most of these parameters. As for sick leave and leg pain, there was no significant difference between Programs 1 and 2, although a difference was observed when comparing Program 3 with each of the other two. Conclusively, it seems that there is human, as well as economical, benefit from a functional restoration program compared to less intensive programs for these patients. AD - Copenhagen Back Centre, National University Hospital, Denmark. AN - 9198257 AU - Bendix, A. F. AU - Bendix, T. AU - Lund, C. AU - Kirkbak, S. AU - Ostenfeld, S. DA - Jun DP - NLM ET - 1997/06/01 IS - 2 KW - Adolescent Adult Chronic Disease Female Follow-Up Studies Humans Low Back Pain/*rehabilitation Male Middle Aged Prospective Studies Single-Blind Method Treatment Outcome LA - eng N1 - Bendix, A F Bendix, T Lund, C Kirkbak, S Ostenfeld, S Clinical Trial Comparative Study Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't Sweden Scand J Rehabil Med. 1997 Jun;29(2):81-9. PY - 1997 SN - 0036-5505 (Print) 0036-5505 SP - 81-9 ST - Comparison of three intensive programs for chronic low back pain patients: a prospective, randomized, observer-blinded study with one-year follow-up T2 - Scand J Rehabil Med TI - Comparison of three intensive programs for chronic low back pain patients: a prospective, randomized, observer-blinded study with one-year follow-up VL - 29 ID - 3474 ER - TY - CHAP A2 - Bobel, C. A2 - Winkler, I. T. A2 - Fahs, B. A2 - Hasson, K. A. A2 - Kissling, E. A. A2 - Roberts, T. A. AB - Benshaul-Tolonen et al. shine a light on two methodological issues impacting a research question that has received much attention recently: whether the provision of menstrual hygiene products reduces schoolgirls’ absenteeism in low-income countries. First, they identify bias in data sources, such as school records and recall data. Second, they show that limiting the focus to menstrual-related absenteeism obscures other threats that menstruation poses to educational attainment, health, and psychosocial well-being. To address these issues, the authors recommend the use of mixed methods, pre-analysis plans, and thoughtful consideration and validation of variables prior to study implementation. They also caution policymakers against overreliance on absenteeism as the sole outcome and overinterpreting results from existing studies that often lack scope and precision. They conclude with a call for more research on the links between menstruation and concentration, learning, self-esteem, and pain management. AD - Department of Women’s, Gender, and Sexuality Studies, University of Massachusetts Boston, Boston, MA, USA. GRID: grid.266685.9. ISNI: 0000 0004 0386 3207 Garden City Park, NY, USA Women and Gender Studies & Social and Cultural Analysis, Arizona State University, Glendale, AZ, USA. GRID: grid.215654.1. ISNI: 0000 0001 2151 2636 Center for Genetics and Society, Berkeley, CA, USA Women’s & Gender Studies, Eastern Washington University, Cheney, WA, USA. GRID: grid.255416.1. ISNI: 0000 0000 9067 4332 Department of Psychology, Colorado College, Colorado Springs, CO, USA. GRID: grid.254544.6. ISNI: 0000 0001 0657 7781 New York, NY, USA Liverpool, UK AN - 33347214 AU - Benshaul-Tolonen, A. AU - Zulaika, G. AU - Sommer, M. AU - Phillips-Howard, P. A. CY - Singapore DO - 10.1007/978-981-15-0614-7_52 LA - eng N1 - Bobel, Chris Winkler, Inga T Fahs, Breanne Hasson, Katie Ann Kissling, Elizabeth Arveda Roberts, Tomi-Ann Benshaul-Tolonen, Anja Zulaika, Garazi Sommer, Marni Phillips-Howard, Penelope A Review Book Chapter NBK565672 [bookaccession] PB - Palgrave Macmillan Copyright 2020, The Author(s). PY - 2020 SP - 705-23 ST - Measuring Menstruation-Related Absenteeism Among Adolescents in Low-Income Countries T2 - The Palgrave Handbook of Critical Menstruation Studies TI - Measuring Menstruation-Related Absenteeism Among Adolescents in Low-Income Countries ID - 4229 ER - TY - JOUR AB - BACKGROUND: Video-assisted thoracic surgery has recently evolved as a viable alternative to thoracotomy for spontaneous pneumothorax. METHODS: A series of 163 patients with primary spontaneous pneumothorax were treated by video-assisted thoracic surgery. Seventy patients were treated for a recurrent episode, 64 patients for a persistent primary spontaneous pneumothorax, 24 patients for a contralateral episode, and 5 patients for a bilateral primary spontaneous pneumothorax. Stapling of bullae with an Endo-GIA stapler (Auto-Suture, Elencourt, France) was performed in 90% of the cases and parietal pleural abrasion was performed in each case. RESULTS: One revisional lateral limited thoracotomy was required for bleeding. Six patients had a prolonged air leak; 2 of them were reoperated on by lateral limited thoracotomy. Two patients have had an incomplete reexpansion of the lung and required a reoperation. The duration of hospitalization was 6.9 +/- 3 days. With a mean follow-up of 24.5 months, three recurrences requiring a reoperation occurred; 3 other patients had a partial recurrence and healed by rest without drainage. The mean time to return to the occupational activity of the patients was 42 +/- 34 days. These results were compared with those of a previous series of 87 patients operated on by lateral limited thoracotomy. CONCLUSIONS: With the development of surgical technique and video equipment, video-assisted thoracic surgery will probably become the treatment of choice of primary spontaneous pneumothorax. AD - Department of Thoracic Surgery, Marie-Lannelongue Hospital, Le Plessis-Robinson, France. AN - 8651762 AU - Bertrand, P. C. AU - Regnard, J. F. AU - Spaggiari, L. AU - Levi, J. F. AU - Magdeleinat, P. AU - Guibert, L. AU - Levasseur, P. DA - Jun DO - 10.1016/0003-4975(96)00190-7 DP - NLM ET - 1996/06/01 IS - 6 KW - Absenteeism Adolescent Adult Case-Control Studies *Endoscopy/adverse effects Female Follow-Up Studies Hospitalization Humans Length of Stay Male Middle Aged Pain, Postoperative/etiology Pleura/surgery Pneumothorax/*surgery Postoperative Hemorrhage/surgery Recurrence Reoperation Retrospective Studies Surgical Staplers Surgical Stapling *Thoracoscopy/adverse effects Thoracotomy Treatment Outcome *Video Recording LA - eng N1 - Bertrand, P C Regnard, J F Spaggiari, L Levi, J F Magdeleinat, P Guibert, L Levasseur, P Comparative Study Journal Article Netherlands Ann Thorac Surg. 1996 Jun;61(6):1641-5. doi: 10.1016/0003-4975(96)00190-7. PY - 1996 SN - 0003-4975 (Print) 0003-4975 SP - 1641-5 ST - Immediate and long-term results after surgical treatment of primary spontaneous pneumothorax by VATS T2 - Ann Thorac Surg TI - Immediate and long-term results after surgical treatment of primary spontaneous pneumothorax by VATS VL - 61 ID - 3540 ER - TY - JOUR AB - Irritable bowel syndrome is a common functional gastrointestinal disorder that affects children and adults. The lack of consensus diagnostic criteria and pathophysiologic understanding has hampered clinical progress in diagnosing and treating this disorder. The recent development of the Rome diagnostic criteria, mapping of brain-gut pathways using neuroimaging, and serotonergic pharmacology have greatly advanced the field. Chronic and acute life stress, especially during childhood, has been recognized as central to the initiation of the disorder and the induction of acute symptoms. We propose a developmental continuum whereby the clinical presentation of irritable bowel syndrome changes with age from irritability during infancy, to diarrhea in toddlers, to recurring abdominal pain during school age, and to pain and altered bowel habits during later adolescence and adulthood. AD - Division of Gastroenterology, Hepatology, and Nutrition, Children's Memorial Hospital, 2300 Children's Plaza, #57, Chicago, IL 60614-3394, USA. AN - 15128493 AU - Besedovsky, A. AU - Li, B. U. DA - Jun DO - 10.1007/s11894-004-0015-4 DP - NLM ET - 2004/05/07 IS - 3 KW - Abdominal Pain/physiopathology Adult Child Diarrhea, Infantile/physiopathology Gastrointestinal Motility Humans Infant Irritable Bowel Syndrome/*diagnosis/drug therapy/epidemiology/*physiopathology Risk Factors LA - eng N1 - Besedovsky, Andres Li, B U K Journal Article Review United States Curr Gastroenterol Rep. 2004 Jun;6(3):247-53. doi: 10.1007/s11894-004-0015-4. PY - 2004 SN - 1522-8037 (Print) 1522-8037 SP - 247-53 ST - Across the developmental continuum of irritable bowel syndrome: clinical and pathophysiologic considerations T2 - Curr Gastroenterol Rep TI - Across the developmental continuum of irritable bowel syndrome: clinical and pathophysiologic considerations VL - 6 ID - 3944 ER - TY - JOUR AB - Objectives: The aim of this study is to determine the prevalence rate and impact of headache in school children on school attendance with particular attention to migraine. Methods: A cross sectional survey was conducted among the school children ranging from 6-17 years old over a period from March 2001 to April 2003. The study was carried out in 10 primary, preparatory and secondary schools. Subjects were selected by multistage stratified sampling procedure. This involved 851 children studying in the first to tenth year of school in the State of Qatar. Results: The present study showed that the prevalence rate of recurrent headache was 85% and migraine 11.9%. Comparing gender frequency of headache, it was noted that it was higher in female students (86.5%) than males (81%). In respect of age, it was observed that the oldest children had more frequent episodes of headache, the highest rate was in the age group of 11 - 15 years old (49%). The most common triggers were fatigue (35.8%) and lack of sleep (17.6%). The most common Symptoms that occurred before headache were change in mood for female students (39.1%) and blurred vision for males (34.6%). The impact of headache on children was frequent absence from school (80%), which affected their school performance. Conclusion: The current study indicated the high prevalence of headache among school children in Qatar, and its effect on school attendance and performance. AN - WOS:000229422200010 AU - Bessisso, M. S. AU - Bener, A. AU - Elsaid, M. F. AU - Al-Khalaf, F. A. AU - Huzaima, K. A. DA - Apr IS - 4 N1 - Bessisso, MS Bener, A Elsaid, MF Al-Khalaf, FA Huzaima, KA Bener, abdulbari/aac-4436-2020 PY - 2005 SN - 0379-5284 SP - 566-570 ST - Pattern of headache in school children in the State of Qatar T2 - Saudi Medical Journal TI - Pattern of headache in school children in the State of Qatar UR - ://WOS:000229422200010 VL - 26 ID - 2771 ER - TY - JOUR AB - OBJECTIVE: To identify prevalence and patterns of complementary and alternative medicine (CAM) use among youth with recurrent headaches (HA) and evaluate associations with co-occurring health problems and limitations as well as with the use and expenditures for conventional medical care. METHODS: Variables were constructed for youth aged 10 to 17 by using linked data from the 2007 National Health Interview Survey and the 2008 Medical Expenditures Panel Survey. Bivariate, logistic, and 2-part regression analyses were used. RESULTS: Of the 10.6% of youth experiencing HA, 29.6% used CAM, rising to 41% for the many HA sufferers who also experienced difficulties with emotions, concentration, behavior, school attendance, or daily activities. Biologically based products (16.2%) and mind-body therapies (13.3%) were most commonly used, especially by the 86.4% of youth with HA experiencing at least 1 other chronic condition. Compared with non-CAM users, youth with HA who used CAM also had higher expenditures for and use of most types of conventional care. CONCLUSIONS: CAM use is most common among youth with HA experiencing multiple chronic conditions and difficulties in daily functioning. Associations among CAM use, multiple chronic conditions, and higher use of conventional care highlight the need for medical providers to routinely ask about CAM use to meet the complex health needs of their patients and facilitate the optimal integration of care. Research is needed to identify models for coordinating complementary and conventional care within a medical home and to understand the health benefits or risks associated with CAM use in conjunction with conventional treatments for patients with HA. AN - WOS:000326475000008 AU - Bethell, C. AU - Kemper, K. J. AU - Gombojav, N. AU - Koch, T. K. DA - Nov DO - 10.1542/peds.2013-1816 IS - 5 N1 - Bethell, Christina Kemper, Kathi J. Gombojav, Narangerel Koch, Thomas K. 1098-4275 PY - 2013 SN - 0031-4005 SP - E1173-E1183 ST - Complementary and Conventional Medicine Use Among Youth With Recurrent Headaches T2 - Pediatrics TI - Complementary and Conventional Medicine Use Among Youth With Recurrent Headaches UR - ://WOS:000326475000008 VL - 132 ID - 2338 ER - TY - JOUR AB - Purpose To report evidence of chronic physical illnesses, mental health disorders, and psychological features as potential risk factors for back pain in children, adolescents, and young adults. Methods This systematic review and meta-analysis included cohort and inception cohort studies that investigated potential risk factors for back pain in young people. Potential risk factors of interest were chronic physical illnesses, mental health disorders (e.g. depression, anxiety), and other psychological features (e.g. coping, resistance). Searches were conducted in MEDLINE, Embase, CINAHL, and Scopus from inception to July 2019. Results Nineteen of 2167 screened articles were included in the qualitative synthesis, and data from 12 articles were included in the meta-analysis. Evidence from inception cohort studies demonstrated psychological distress, emotional coping problems, and somatosensory amplification to be likely risk factors for back pain. Evidence from non-inception cohort studies cannot distinguish between risk factors or back pain triggers. However, we identified several additional factors that were associated with back pain. Specifically, asthma, headaches, abdominal pain, depression, anxiety, conduct problems, somatization, and 'feeling tense' are potential risk factors or triggers for back pain. Results from the meta-analyses demonstrated the most likely risk factors for back pain in young people are psychological distress and emotional coping problems. Conclusion Psychological features are the most likely risk factors for back pain in young people. Several other factors were associated with back pain, but their potential as risk factors was unclear due to risk of bias. Additional high-quality research is needed to better elucidate these relationships. Graphic abstract These slides can be retrieved under Electronic Supplementary Material. AN - WOS:000519664000011 AU - Beynon, A. M. AU - Hebert, J. J. AU - Hodgetts, C. J. AU - Boulos, L. M. AU - Walker, B. F. DA - Mar DO - 10.1007/s00586-019-06278-6 IS - 3 N1 - Beynon, Amber M. Hebert, Jeffrey J. Hodgetts, Christopher J. Boulos, Leah M. Walker, Bruce F. Hodgetts, Christopher/0000-0001-6474-8155; Hebert, Jeffrey/0000-0002-6959-325X; Boulos, Leah/0000-0002-9849-383X; Walker, Bruce/0000-0002-8506-6740; Beynon, Amber/0000-0002-1302-4429 1432-0932 PY - 2020 SN - 0940-6719 SP - 480-496 ST - Chronic physical illnesses, mental health disorders, and psychological features as potential risk factors for back pain from childhood to young adulthood: a systematic review with meta-analysis T2 - European Spine Journal TI - Chronic physical illnesses, mental health disorders, and psychological features as potential risk factors for back pain from childhood to young adulthood: a systematic review with meta-analysis UR - ://WOS:000519664000011 VL - 29 ID - 1838 ER - TY - JOUR AB - The social and demographic characteristics of similar to 65,000 Tibetan refugees in India were determined from data collected 1994-1996. Approximately 55,000 refugees were living in 37 settlements widely distributed around India. The remaining 10,000 refugees were monks living in monasteries associated with some of the settlements. mostly in the south of India. In the settlements, a community-based surveillance system was established and data were collected by trained community health workers in house to house visits. In the monasteries, data were collected by the community health workers in monthly interviews with a designated liaison monk at each monastery. These data indicated little immigration of new civilian refugees in the past 10 years into the settlements but a steady influx of new monks into the monasteries. The age distribution in the settlements showed a prominent mode in the 15-25 year age range, a declining birth rate, and an increasing proportion of elderly. In general, refugees born in India were educated through secondary school, while refugees born in Tibet were often illiterate. The principle occupations were education involving 27% (including students), farming, 16%, and sweater selling, 6.5%: another 6.5% were too young or too old for employment, and only 2.4% were unemployed. The overall crude birth rate was determined to be relatively low at 16.8/1000, although this may underestimate the true figure. Infant mortality varied from 20 to 3511000 live births in the different regions. Child vaccination programs cover less than 50% of the population. The burden of illness in this society was mainly characterized by diarrhoea, skin infections, respiratory infections, fevers, and, among the elderly, joint pains and cardiovascular problems. Although calculated death rates were unrealistically low, due to under-reporting, causes of death, derived from "verbal autopsies", were mainly cancer, tuberculosis, accidents, cirrhosis and heart disease in order of decreasing frequency. Overall. the sociodemographic and health characteristics of this population appear to be in transition from those typical of the least developed countries to those typical of middle income and more affluent societies. (C) 2002 Elsevier Science Ltd. All rights reserved. AN - WOS:000173266800009 AU - Bhatia, S. AU - Dranyi, T. AU - Rowley, D. DA - Feb DO - 10.1016/s0277-9536(01)00040-5 IS - 3 N1 - Bhatia, S Dranyi, T Rowley, D PY - 2002 SN - 0277-9536 SP - 411-422 ST - A social and demographic study of Tibetan refugees in India T2 - Social Science & Medicine TI - A social and demographic study of Tibetan refugees in India UR - ://WOS:000173266800009 VL - 54 ID - 2837 ER - TY - JOUR AB - BACKGROUND: Functional gastrointestinal diseases (FGIDs) are emerging as an important cause of morbidity in adolescents globally. The prevalence of FGIDs among Indian children or adolescents is not clear. METHODS: A cross-sectional school-based survey conducted in 1115 children aged 10-17 years attending four semi urban government schools of National capital territory (NCT) of Delhi. Rome III questionnaire was translated into Hindi and was filled by the students under supervision. Prevalence of FGIDs was calculated. RESULTS: Ten percent (112) adolescents had FGIDs. Out of 112, 52 % (58) were boys, and 48 % (54) were girls. 2.7 % (30) had functional dyspepsia, 1.3 % (15) had irritable bowel syndrome, 1.4 % (16) had abdominal migraine, 1.5 % (17) had aerophagia, 0.4 % (5) had functional abdominal pain syndrome, and 0.3 % (4) had functional abdominal pain. Prevalence of functional constipation, adolescent rumination syndrome, cyclical vomiting syndrome, and non-retentive fecal incontinence were 0.5 % (6), 0.3 % (4), 0.3 % (3), 0.4 % (5), respectively. Functional abdominal pain-related FGID were present in 6.3 % (70) children (35 boys and 35 girls). Functional constipation (4 vs. 2) and functional abdominal pain syndrome (4 vs. 1, p < 0.05) were significantly more in females. CONCLUSIONS: The prevalence of functional gastrointestinal disorders in our study was 10 %. The most frequent FGID noted was functional dyspepsia. AD - Apollo Centre for Advanced Pediatrics, Indraprastha Apollo Hospital, Sarita Vihar, Delhi Mathura Road, New Delhi, 110 076, India. Department of Pediatrics, PGIMER and Dr. Ram Manohar Lohia Hospital, Baba Kharak Singh Marg, New Delhi, 110 001, India. shivanipaeds@gmail.com. AN - 27554498 AU - Bhatia, V. AU - Deswal, S. AU - Seth, S. AU - Kapoor, A. AU - Sibal, A. AU - Gopalan, S. DA - Jul DO - 10.1007/s12664-016-0680-x DP - NLM ET - 2016/08/25 IS - 4 KW - Adolescent Age Factors Child Cross-Sectional Studies Dyspepsia/epidemiology Female Gastrointestinal Diseases/*epidemiology Humans India/epidemiology Male Morbidity Prevalence Schools/*statistics & numerical data Adolescent health Functional disorders Gastroenterology School health LA - eng N1 - 0975-0711 Bhatia, Vidyut Deswal, Shivani Seth, Swati Kapoor, Akshay Sibal, Anupam Gopalan, Sarath Journal Article India Indian J Gastroenterol. 2016 Jul;35(4):294-8. doi: 10.1007/s12664-016-0680-x. Epub 2016 Aug 24. PY - 2016 SN - 0254-8860 SP - 294-8 ST - Prevalence of functional gastrointestinal disorders among adolescents in Delhi based on Rome III criteria: A school-based survey T2 - Indian J Gastroenterol TI - Prevalence of functional gastrointestinal disorders among adolescents in Delhi based on Rome III criteria: A school-based survey VL - 35 ID - 3803 ER - TY - JOUR AB - Dysmenorrhea is the most common of gynecologic complaints. It affects half of all female adolescents today and represents the leading cause of periodic college/school absenteeism among that population. To evaluate the menstrual problem specially dysmenorrhea and its severity in female medical students and its effect on their regular activities. They affect 80% of women at some time in their lives; usually they are not assigning of a serious underlying problems. It is a condition where there will be painful menstruation associated with abdominal cramps, backache, nausea and vomiting, stiffness in thighs, cramps in calf muscles. Pain usually last for 2 or 3 days and tends to happen in the first few days of the period. Up to 15% of women have period pains, severe enough to interfere with their daily activities. This can lead to missing days at work or diseased participation in social or sporting activities. Dysmenorrhea is of two type namely primary and secondary dysmenorrhoea. Primary dysmenorrhoea is used to describe normal period pain experienced by many women during the time of their period and there is no underlying medical problem. Secondary dysmenorrhoea is used to describe pain results of an underlying gynecological problem. There are number of measures like sitz bath, simple morning walk and dietotherapy. There are number of herbal drugs mentioned in Unani literature which are useful in tackling this problem. The review highlights about dysmenorrhoea and some of those herbal drugs which are used in Unani System of medicine. AN - WOS:000218687700006 AU - Bhatl, S. A. AU - Raza, A. AU - ParasWani AU - Shahbuddin DA - Jan IS - 1 N1 - Bhatl, Shabir Ahmad Raza, Aysha ParasWani Shahbuddin PY - 2015 SN - 2349-7750 SP - 539-542 ST - CONCEPT AND MANAGEMENT OF DYSMENORRHEA IN UNANI SYSTEM OF MEDICINE T2 - Indo American Journal of Pharmaceutical Sciences TI - CONCEPT AND MANAGEMENT OF DYSMENORRHEA IN UNANI SYSTEM OF MEDICINE UR - ://WOS:000218687700006 VL - 2 ID - 2265 ER - TY - JOUR AB - A boy aged 10 is assigned on a diagnosis of migraine and allergy. While numerous studies have confirmed the effect of acupuncture in case of tension headache or migraine, allergy as well apparently responds to needling. In individual studies effectiveness in children with cephalea was proven, too. Is classical acupuncture suitable for successful treatment of children? Two experts present different approaches to painless and yet effective treatment of school children. AN - WOS:000358086100009 AU - Bijak, M. AU - Stockert, K. AU - Wernicke, T. DO - 10.1016/s0415-6412(15)30012-6 IS - 2 N1 - Bijak, M. Stockert, K. Wernicke, T. 1439-4359 PY - 2015 SN - 0415-6412 SP - 31-33 ST - Child with headache and allergy T2 - Deutsche Zeitschrift Fur Akupunktur TI - Child with headache and allergy UR - ://WOS:000358086100009 VL - 58 ID - 2258 ER - TY - JOUR AB - Sickle cell disease (SCD), an inherited blood disorder that primarily affects individuals of African descent, is associated with serious medical complications as well as numerous social-environmental risk factors. These social-environmental factors are linked to long-standing social inequities, such as financial hardship and racial discrimination, both of which impact cognitive and behavioral functioning in youth. Previous research on the relationship between social-environmental risk and psychological functioning has primarily relied on non-modifiable, unidimensional measures of socioeconomic status (SES), such as income and parental education, as a proxy for social-environmental risk. The current study aimed to address the limitations associated with typical SES-type measures by comparing the unique and shared association of SES and more targeted and modifiable social-environmental factors (e.g., parent and family functioning) with specific areas of cognitive and behavioral adjustment in pediatric SCD. Seventy children ages 4-8 years old and their parents completed measures of social-environmental risk and psychological adjustment. Exploratory factor analysis indicated parent and family functioning measures were largely independent of SES. Parent and family functioning predicted phonological processing and ADHD symptoms above and beyond SES alone. In addition, the predictive ability of social-environmental risk factors appears to vary by genotype severity for measures of social functioning and math problem-solving ability. Future studies are needed to explore more specific and well-supported models of modifiable social-environmental risk and the relative impact of social-environmental risk on cognitive and behavioral functioning. AN - WOS:000586020700006 AU - Bills, S. E. AU - Schatz, J. AU - Hardy, S. J. AU - Reinman, L. DA - Jan DO - 10.1080/09297049.2019.1577371 IS - 1 N1 - Bills, Sarah E. Schatz, Jeffrey Hardy, Steven J. Reinman, Laura Hardy, Steven/0000-0002-0491-4980; Schatz, Jeffrey/0000-0002-5129-2344 1744-4136 PY - 2020 SN - 0929-7049 SP - 83-99 ST - Social-environmental factors and cognitive and behavioral functioning in pediatric sickle cell disease T2 - Child Neuropsychology TI - Social-environmental factors and cognitive and behavioral functioning in pediatric sickle cell disease UR - ://WOS:000586020700006 VL - 26 ID - 1850 ER - TY - JOUR AB - BACKGROUND: Chronic pain affects 1-3 million Canadian children and adolescents and their families. The primary objective of the Partnering For Pain project was to collaboratively identify the top 10 research priorities in pediatric chronic pain. METHODS: Partnering For Pain took a patient-oriented research approach and followed a modified James Lind Alliance Priority Setting Partnership (PSP) to identify the top research priorities in pediatric chronic pain according to people with lived experience (patients), family members and health care providers (clinicians). The PSP was completed in 4 phases between May and December 2018: 1) national survey of stakeholders, including those with lived experience with pediatric chronic pain, family members and clinicians who treat children with chronic pain, to gather priorities, 2) data processing, 3) interim prioritization by invited patients, family members and clinicians (former research participants or identified through pediatric chronic pain programs, patient partner organizations and steering committee member networks) and 4) in-person priority-setting workshop involving patients, family members and clinicians identified via steering committee networks and partner organizations, with evaluation of patient engagement. The process was led by a national steering committee of patient and parent partners, researchers and clinicians engaged in codesign, analysis and translation of project findings. RESULTS: In phase 1, 215 Canadians (86 patients [40.0%], 56 family members [26.0%] and 73 clinicians [34.0%]) submitted 540 potential priorities that were developed into 112 unique research questions (phase 2). Of the 112 questions, 63 were rated for importance by 57 participants (19 patients [33%], 17 family members [30%] and 21 clinicians [37%]) in phase 3. In phase 4, 20 participants (6 patients [30%], 6 family members [30%] and 8 clinicians [40%]) discussed the 25 most highly rated questions and reached consensus on the final top 10. INTERPRETATION: The final priorities address pediatric chronic pain prevention, impact and treatment, as well as delivery, access and coordination of care. The priorities reflect a directed and collaborative call to action to improve existing pediatric pain research and care. PLAIN LANGUAGE SUMMARY: Chronic pain affects 1 in 5 children and teens. This means that 1-3 million Canadian youth deal with pain lasting months to years. This pain gets in the way of being active, sleeping, going to school, and getting along with friends and family. Youth with chronic pain and their families are experts on what it's like to live with pain, but, until now, research has not asked what issues they care about most. The goal of the Partnering For Pain project was to develop a list of the 10 most important things we still need to learn about chronic pain during childhood according to people who live with it, their families and health care providers. We did this in 4 steps: 1) a survey with 215 people who shared 540 concerns they have about chronic pain in childhood, 2) turning those concerns into questions that can be answered by research, 3) a survey with 57 people who ranked how important each research question was and 4) an in-person discussion with 20 people who chose the top 10 research priorities. Each step included Canadians who have had chronic pain during childhood, their families and health care providers. The final top 10 list has questions about how to better prevent and care for children and teens with chronic pain. These priorities make sure that future research focuses on what is most important to people who will use it in their everyday lives. Project video: https://youtu.be/wA-RwrFiSPk. Project website: www.partneringforpain.com. AD - University of Toronto and The Hospital for Sick Children (Birnie, Stinson), Toronto, Ont.; patient partner (K. Dib, M. Dib), Halifax, NS; patient partner (Ouellette), McMaster University, Hamilton, Ont.; parent partner (Nelson), Windsor, Ont.; parent partner (Pahtayken), Onion Lake, Sask.; Department of Pediatrics (Baerg), University of Saskatchewan, Saskatoon, Sask.; Dalhousie University and IWK Health Centre (Chorney), Halifax, NS; University of Ottawa (Forgeron, Lamontagne, Poulin); Children's Hospital of Eastern Ontario (Lamontagne), Ottawa, Ont.; University of Calgary (Noel), Calgary, Alta.; The Ottawa Hospital (Poulin), Ottawa, Ont. kathryn.birnie@sickkids.ca. University of Toronto and The Hospital for Sick Children (Birnie, Stinson), Toronto, Ont.; patient partner (K. Dib, M. Dib), Halifax, NS; patient partner (Ouellette), McMaster University, Hamilton, Ont.; parent partner (Nelson), Windsor, Ont.; parent partner (Pahtayken), Onion Lake, Sask.; Department of Pediatrics (Baerg), University of Saskatchewan, Saskatoon, Sask.; Dalhousie University and IWK Health Centre (Chorney), Halifax, NS; University of Ottawa (Forgeron, Lamontagne, Poulin); Children's Hospital of Eastern Ontario (Lamontagne), Ottawa, Ont.; University of Calgary (Noel), Calgary, Alta.; The Ottawa Hospital (Poulin), Ottawa, Ont. AN - 31699686 AU - Birnie, K. A. AU - Dib, K. AU - Ouellette, C. AU - Dib, M. A. AU - Nelson, K. AU - Pahtayken, D. AU - Baerg, K. AU - Chorney, J. AU - Forgeron, P. AU - Lamontagne, C. AU - Noel, M. AU - Poulin, P. AU - Stinson, J. C2 - PMC6839970 DA - Oct-Dec DO - 10.9778/cmajo.20190060 DP - NLM ET - 2019/11/09 IS - 4 LA - eng N1 - 2291-0026 Birnie, Kathryn A Dib, Katherine Ouellette, Carley Dib, Mary Anne Nelson, Kimberly Pahtayken, Dolores Baerg, Krista Chorney, Jill Forgeron, Paula Lamontagne, Christine Noel, Melanie Poulin, Patricia Stinson, Jennifer Journal Article CMAJ Open. 2019 Nov 7;7(4):E654-E664. doi: 10.9778/cmajo.20190060. Print 2019 Oct-Dec. PY - 2019 SN - 2291-0026 (Print) 2291-0026 SP - E654-e664 ST - Partnering For Pain: a Priority Setting Partnership to identify patient-oriented research priorities for pediatric chronic pain in Canada T2 - CMAJ Open TI - Partnering For Pain: a Priority Setting Partnership to identify patient-oriented research priorities for pediatric chronic pain in Canada VL - 7 ID - 4025 ER - TY - JOUR AB - Poor access to pediatric chronic pain care is a longstanding concern. The COVID-19 pandemic has necessitated virtual care delivery at an unprecedented pace and scale. We conducted a scoping review to create an interactive Evidence and Gap Map (EGM) of virtual care solutions across a stepped care continuum (i.e., from self-directed to specialist care) for youth with chronic pain and their families. Review methodology was co-designed with 8 youth with chronic pain and 7 parents/caregivers. Data sources included peer-reviewed scientific literature, grey literature (app stores, websites), and a call for innovations. Records were independently coded and assessed for quality. Overall, 185 records were included (105 scientific records, 56 apps, 16 websites, and 8 innovations). Most virtual care solutions were applicable across pediatric chronic pain diagnoses, with the greatest proportion at lower levels of stepped care (i.e., >100 self-guided apps and websites). Virtual delivery of psychological strategies was common. Evidence gaps were noted at higher levels of stepped care (i.e., requiring more resource and health professional involvement), integration with health records, communication with health professionals, web accessibility, and content addressing social/family support, medications, school, substance use, sleep, diet, and acute pain flares or crises. EGMs are a novel visual knowledge synthesis tool that enable rapid evidence-informed decision-making by patients and families, health professionals, and policymakers. This EGM identified high quality virtual care solutions for immediate scale and spread, and areas with no evidence in need of prioritization. Virtual care should address priorities identified by youth with chronic pain and their families. AD - Department of Anesthesiology, Perioperative and Pain Medicine, University of Calgary, Calgary, AB, Canada Department of Community Health Sciences, University of Calgary, Calgary, AB, Canada Alberta Children's Hospital Research Institute, Calgary, AB, Canada Solutions for Kids in Pain (SKIP), Halifax, NS, Canada Department of Psychology, University of Calgary, Calgary, AB, Canada Northern Ontario School of Medicine, Thunder Bay, ON, Canada Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada Lawrence S. Bloomberg, Faculty of Nursing, University of Toronto, Toronto, ON, Canada Health Sciences Library & Department of Community Health Sciences, University of Calgary, Calgary, AB, Canada Department of Anesthesia & Pain Medicine, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada Institute for Health Policy, Management & Evaluation, University of Toronto, Toronto, ON, Canada. AN - 34050111 AU - Birnie, K. A. AU - Pavlova, M. AU - Neville, A. AU - Noel, M. AU - Jordan, I. AU - Jordan, E. AU - Marianayagam, J. AU - Stinson, J. AU - Lorenzetti, D. L. AU - Faulkner, V. AU - Killackey, T. AU - Campbell, F. AU - Lalloo, C. DA - May 28 DO - 10.1097/j.pain.0000000000002339 DP - NLM ET - 2021/05/30 LA - eng N1 - 1872-6623 Birnie, Kathryn A Pavlova, Maria Neville, Alexandra Noel, Melanie Jordan, Isabel Jordan, Evie Marianayagam, Justina Stinson, Jennifer Lorenzetti, Diane L Faulkner, Violeta Killackey, Tieghan Campbell, Fiona Lalloo, Chitra Journal Article United States Pain. 2021 May 28. doi: 10.1097/j.pain.0000000000002339. PY - 2021 SN - 0304-3959 ST - Rapid evidence and gap map of virtual care solutions across a stepped care continuum for youth with chronic pain and their families in response to the COVID-19 pandemic T2 - Pain TI - Rapid evidence and gap map of virtual care solutions across a stepped care continuum for youth with chronic pain and their families in response to the COVID-19 pandemic ID - 4071 ER - TY - JOUR AB - BACKGROUND: The comorbidity of headache and psychiatric symptoms is a well-recognized clinical phenomenon, but there are only limited data regarding the temporal relationship between headache and symptoms of anxiety and depression as well as behavioral problems in adolescents. This study investigates the relationship of anxiety and depressive symptoms and behavioral problems at baseline with recurrent headache at follow-up four years later. METHODS: Within the Nord-Trøndelag Health Study (HUNT), including repeated population-based studies conducted in Norway, 2399 adolescents in junior high schools aged 12-16 years (77% of the invited) participated in Young-HUNT1 (1995-1997) and again at follow-up four years later, in Young-HUNT2 (2000-2001). The same comprehensive questionnaire that included assessment of symptoms of anxiety and depression and behavioral problems, i.e. conduct and attention difficulties was completed in both studies. In addition 1665 of the participants were interviewed about their headache complaints in Young-HUNT2. RESULTS: In adjusted multivariate analyses we found that higher scores of anxiety and depressive symptoms at baseline were associated with recurrent headache at follow-up four years later (OR: 1.6, 95% CI: 1.2-2.1, p = 0.001), evident for migraine (OR: 1.8, 95% CI: 1.2-2.7, p = 0.008) and non-classifiable headache (OR: 1.7, 95% CI: 1.0-2.8, p = 0.034), but not statistically significant for tension-type headache (OR: 1.4, 95% CI: 1.0-1.9, p = 0.053). Higher scores of anxiety and depressive symptoms at baseline were significantly associated with more frequent headache at follow-up (monthly vs. no recurrent headache OR: 1.8, 95% CI: 1.3-2.5, p = 0.001, weekly or daily vs. no recurrent headache OR: 1.9, 95% CI: 1.2-2.9, p = 0.005). Among adolescents without recurrent headache at baseline, higher scores for symptoms of anxiety and depression were associated with new onset migraine four years later (OR: 2.6, 95% CI: 1.1-4.8, p = 0.036). Higher scores of attention problems at baseline were associated with non-classifiable headache at follow-up (OR: 2.0, 95% CI: 1.3-3.4, p = 0.017). CONCLUSIONS: Results from the present study showed that symptoms of anxiety and depression in early adolescence were associated with recurrent headache four years later. Recognizing anxiety and depressive symptoms should be considered part of the clinical assessment in young headache patients, as early identification of these associated factors may lead to improved headache management. AD - Department of Neurology, Vestfold Hospital, Tønsberg, Norway. britaj@mac.com. AN - 25595046 AU - Blaauw, B. A. AU - Dyb, G. AU - Hagen, K. AU - Holmen, T. L. AU - Linde, M. AU - Wentzel-Larsen, T. AU - Zwart, J. A. C2 - PMC4405520 DA - Jan 16 DO - 10.1186/1129-2377-16-10 DP - NLM ET - 2015/01/18 KW - Adolescent *Adolescent Behavior/psychology Anxiety/*epidemiology/psychology Child Comorbidity Depression/*epidemiology/psychology Female Follow-Up Studies Headache/*epidemiology/psychology Humans Male Mental Disorders/*epidemiology/psychology Norway/epidemiology Recurrence Young Adult LA - eng N1 - 1129-2377 Blaauw, Brit A Dyb, Grete Hagen, Knut Holmen, Turid L Linde, Mattias Wentzel-Larsen, Tore Zwart, John-Anker Journal Article J Headache Pain. 2015 Jan 16;16:10. doi: 10.1186/1129-2377-16-10. PY - 2015 SN - 1129-2369 (Print) 1129-2369 SP - 10 ST - The relationship of anxiety, depression and behavioral problems with recurrent headache in late adolescence – a Young-HUNT follow-up study T2 - J Headache Pain TI - The relationship of anxiety, depression and behavioral problems with recurrent headache in late adolescence – a Young-HUNT follow-up study VL - 16 ID - 3254 ER - TY - JOUR AB - Purpose of review Endometriosis can exist in the adolescent female. It can be a very disruptive disease and cause significant dysfunction at a time in life when self-esteem, school attendance, and school performance are critical to achievement of life goals. Approaches to diagnosis and management in the recent literature are reviewed, focusing on those that apply directly to the adolescent or indirectly, by extrapolation from work done in the adult population. Practical strategies for adolescent patient care are presented. Recent findings Recent research has focused on the efficacy of current treatment modalities and management of potential adverse side effects. Possible etiologies of endometriosis have been proposed, and therapies directed at those causes are being explored. Methods of diagnosis, both invasive and noninvasive, have been studied in order to determine the most effective way of diagnosing the disease. Summary A better understanding of the etiology of endometriosis would probably assist in determining the most suitable treatment strategies. Future work in adolescent endometriosis should focus on developing safe, minimally invasive, yet definitive options for diagnosis and treatment. AN - WOS:000178349600005 AU - Black, A. Y. AU - Jamieson, M. A. DA - Oct DO - 10.1097/00001703-200210000-00005 IS - 5 N1 - Black, AY Jamieson, MA 1473-656x PY - 2002 SN - 1040-872X SP - 467-474 ST - Adolescent endometriosis T2 - Current Opinion in Obstetrics & Gynecology TI - Adolescent endometriosis UR - ://WOS:000178349600005 VL - 14 ID - 2821 ER - TY - JOUR AB - INTRODUCTION: Emergency department (ED) overcrowding has been a significant problem for the last 10 years. Several studies have shown that a relatively small number of ED patients are responsible for a disproportionate amount of ED visits. This study aims to describe the frequent users of our emergency department. METHODS: This was an institutional review board-approved descriptive study performed by a retrospective review of electronic records. This pilot describes and compares patients who had 12 or more ED visits during the study year with those who visited less. RESULTS: The 234 patients who met criteria for high-frequency use (HFU) of the emergency department were responsible for a total of 4633 visits. Sex, race, and age distribution of HFU patients were similar to those of general ED patients. Eighty-four percent of HF users have insurance and 93% have primary care providers. A relatively small percentage of HFU visits, 4%, were mental health-related visits and 3% were alcohol- and drug-related visits. The HFU visits are socially connected: 93% have their own homes; 94% have relatives or friends; 73% have a religious affiliation. Pain or pain-related conditions are the most common diagnoses. These patients are also frequent users of ambulatory care services. CONCLUSION: The similarities between our HFU and the general ED population are more numerous than their differences. The HFU patients of our emergency department are different in terms of age, employment status, and type of insurance. IMPLICATIONS FOR NURSES: A detailed description of local HFU may help to inform planning and better meet ED patients' needs. As one of many results of this study, the ED chairman met with the Hematology-Oncology team and reviewed the protocol for ED management of sickle cell crisis. The meeting resulted in a revised protocol, including an immediate change in their pain medication from meperidine to either morphine or hydromorphone. AD - Department of Emergency Medicine, Baystate Medical Center, 759 Chestnut Street, Springfield, MA 01199, USA. Del.Blank@bhs.org AN - 15834378 AU - Blank, F. S. AU - Li, H. AU - Henneman, P. L. AU - Smithline, H. A. AU - Santoro, J. S. AU - Provost, D. AU - Maynard, A. M. DA - Apr DO - 10.1016/j.jen.2005.02.008 DP - NLM ET - 2005/04/19 IS - 2 KW - Academic Medical Centers/*statistics & numerical data Adolescent Adult Age Distribution Aged Anemia, Sickle Cell/epidemiology/therapy Continental Population Groups/statistics & numerical data Diagnosis-Related Groups/statistics & numerical data Emergency Nursing/organization & administration Emergency Service, Hospital/*statistics & numerical data Employment/statistics & numerical data Female Health Care Surveys Health Services Accessibility/organization & administration Health Services Misuse/*statistics & numerical data Health Services Needs and Demand Humans Insurance, Health/statistics & numerical data Male Massachusetts/epidemiology Middle Aged Pain/epidemiology Pain Management Patient Acceptance of Health Care/*statistics & numerical data Pilot Projects Retrospective Studies Sex Distribution Social Support LA - eng N1 - Blank, Fidela S J Li, Haiping Henneman, Philip L Smithline, Howard A Santoro, John S Provost, Deborah Maynard, Ann M Journal Article United States J Emerg Nurs. 2005 Apr;31(2):139-44. doi: 10.1016/j.jen.2005.02.008. PY - 2005 SN - 0099-1767 (Print) 0099-1767 SP - 139-44 ST - A descriptive study of heavy emergency department users at an academic emergency department reveals heavy ED users have better access to care than average users T2 - J Emerg Nurs TI - A descriptive study of heavy emergency department users at an academic emergency department reveals heavy ED users have better access to care than average users VL - 31 ID - 3895 ER - TY - JOUR AB - The Quantitative Sensory Testing (QST) protocol of the German research network on neuropathic pain (DFNS) encompassing all somatosensory modalities assesses the functioning of different nerve fibers and of central pathways. The aim of our study was: (1) to explore, whether this QST protocol is feasible for children, (2) to detect distribution properties of QST data and the impact of body site, age and gender and (3) to establish reference values for QST in children and adolescents. The QST protocol of the DFNS with modification of instructions and pain rating was used in 176 children aged 6.12-16.12 years for six body sites. QST was feasible for children over 5 years of age. ANOVAs revealed developmental, gender and body site differences of somatosensory functions similar to adults. The face was more sensitive than the hand and/or foot. Younger children (6-8 years) were generally less sensitive to all thermal and mechanical detection stimuli but more sensitive to all pain stimuli than older (9-12 years) children, whereas there were little differences between older children and adolescents (13-17 years). Girls were more sensitive to thermal detection and pain stimuli, but not to mechanical detection and pain stimuli. Reference values differ from adults, but distribution properties (range, variance, and side differences) were similar and plausible for statistical factors. Our results demonstrate that the full QST protocol is feasible and valid for children over 5 years of age with their own reference values. (C) 2010 International Association for the Study of Pain. Published by Elsevier B. V. All rights reserved. AN - WOS:000275789500014 AU - Blankenburg, M. AU - Boekens, H. AU - Hechler, T. AU - Maier, C. AU - Krumova, E. AU - Scherens, A. AU - Magerl, W. AU - Aksu, F. AU - Zernikow, B. DA - Apr DO - 10.1016/j.pain.2010.01.011 IS - 1 N1 - Blankenburg, M. Boekens, H. Hechler, T. Maier, C. Krumova, E. Scherens, A. Magerl, W. Aksu, F. Zernikow, B. Enax-Krumova, Elena/J-5638-2019 Enax-Krumova, Elena/0000-0002-6162-9414 1872-6623 PY - 2010 SN - 0304-3959 SP - 76-88 ST - Reference values for quantitative sensory testing in children and adolescents: Developmental and gender differences of somatosensory perception T2 - Pain TI - Reference values for quantitative sensory testing in children and adolescents: Developmental and gender differences of somatosensory perception UR - ://WOS:000275789500014 VL - 149 ID - 2560 ER - TY - JOUR AB - Primary headache disorders such as migraine and tension-type headache begin as early as childhood or adolescence. Prevalence increases during primary school and adolescence. In tension-type headache, central pain sensitization and activation of central nociceptive neurons plays an important role. Migraine is a primary brain disorder with abnormalities in pain modulating systems and cortical stimulus processing. Bio-psycho-social factors play a decisive role in both types of headache. Secondary headaches due to an inflammatory or a structural brain alteration are rare. Diagnosis is based on clinical criteria. Typical recurrent headaches are diagnosed by patient's history and physical examination. In case of abnormalities, further diagnostic is needed. Treatment of tension-type headache is focused on multimodal pain therapy, treatment of migraine is focused on medication of attacks and secondary headaches need treatment of the underlying disease. Treatment goals are the reduction of pain perception, promotion of control and self-efficacy experiences, the increase of physical performance as well as the resumption of normal everyday structures and social contacts as a prerequisite for an increasing pain reduction. AN - WOS:000455222400002 AU - Blankenburg, M. AU - Schroth, M. AU - Braun, S. DA - Jan DO - 10.1055/a-0710-5014 IS - 1 N1 - Blankenburg, Markus Schroth, Michael Braun, Sarah 1439-3824 PY - 2019 SN - 0300-8630 SP - 14-20 ST - Chronic Headache in Children and Adolescents T2 - Klinische Padiatrie TI - Chronic Headache in Children and Adolescents UR - ://WOS:000455222400002 VL - 231 ID - 1971 ER - TY - JOUR AB - The authors examined associations among parental and child adjustment, child syncope, somatic, and school problems. Participants were children (N = 56) ages 7-18 years with syncope. Measures included syncope severity, parental distress, and children's internalizing symptoms. For children diagnosed negative for neurocardiogenic syncope (NCS), their fathers' and their own psychological symptoms were positively associated with the severity of syncope, whereas their mothers' functioning was negatively associated with the severity of syncope. Also, for the negative NCS group, fathers' psychological functioning was associated with children's nonsyncope somatic complaints but not with their school problems. For the positive NCS group, few significant father-child associations were found, but several significant positive associations were revealed between mothers' psychological symptoms and their children's syncope as well as somatic and school problems. AN - WOS:000222924600006 AU - Blount, R. L. AU - Morris, J. A. B. AU - Cheng, P. S. AU - Campbell, R. M. AU - Brown, R. T. DA - Aug DO - 10.1037/0022-006x.72.4.597 IS - 4 N1 - Blount, RL Morris, JAB Cheng, PS Campbell, RM Brown, RT Brown, Ronald/0000-0002-9656-4614 PY - 2004 SN - 0022-006X SP - 597-604 ST - Parent and child psychological factors in pediatric syncope and other somatic symptoms T2 - Journal of Consulting and Clinical Psychology TI - Parent and child psychological factors in pediatric syncope and other somatic symptoms UR - ://WOS:000222924600006 VL - 72 ID - 2787 ER - TY - JOUR AB - OBJECTIVE: To study the prevalence of complaints of recurrent abdominal pain (RAP) among school children aged 11-12 years in a rural setting in Malaysia. METHODOLOGY: Questionnaires were distributed to all parents and teachers of children aged 11-12 years who attended a small rural school in which all the children were Malays. Complaints of RAP were defined as at least three such complaints occurring over a period of at least 3 months. RESULTS: One hundred and sixty questionnaires were distributed, of which 148 were returned, giving a response rate of 92.5%. Sixty-one children (41.2%) had RAP. Approximately 45.2% of girls and 35.9% of boys reported having RAP. Compared with children without RAP, there was a significantly larger number of children with RAP (85.2%) who had at least one stress factor (P = 0.0109). There were no significant associations between RAP and total family income (P = 0.0573), a history of abdominal pain in at least one parent (P = 0.1686), a history of abdominal pain in at least one sibling (P = 0.0617), academic performance (P = 0.9967) or the degree of sports participation (P = 0.8469). There was an increased incidence of other systemic complaints in children with RAP when compared with children without RAP. CONCLUSION: Recurrent abdominal pain was found to be common among 11- to 12-year-old children in a rural Malay school. There was a significant association found between RAP and the presence of stressful events, as well as with the presence of other systemic complaints. AD - Department of Paediatrics, University of Malaya Medical Centre, Kuala Lumpur, Malaysia. boeycm@medicine.med.um.edu.my AN - 10404456 AU - Boey, C. C. AU - Yap, S. B. DA - Jun DO - 10.1046/j.1440-1754.1999.00366.x DP - NLM ET - 1999/07/15 IS - 3 KW - Abdominal Pain/*epidemiology/psychology Child Chronic Disease Female Humans Malaysia/epidemiology Male Prevalence Risk Factors Rural Population Socioeconomic Factors Stress, Psychological/complications LA - eng N1 - Boey, C C Yap, S B Journal Article Australia J Paediatr Child Health. 1999 Jun;35(3):303-5. doi: 10.1046/j.1440-1754.1999.00366.x. PY - 1999 SN - 1034-4810 (Print) 1034-4810 SP - 303-5 ST - An epidemiological survey of recurrent abdominal pain in a rural Malay school T2 - J Paediatr Child Health TI - An epidemiological survey of recurrent abdominal pain in a rural Malay school VL - 35 ID - 3562 ER - TY - JOUR AB - Aim. To look at predictors of consulting behaviour among children with recurrent abdominal pain in a rural community in Malaysia. Subjects and methods. A sample of 1462 school-children aged between 9 and 15 years were randomly selected from all schools in Kuala Langat, a rural district in Malaysia. Those with recurrent abdominal pain, defined according to Apley's criteria, were recruited and divided into consulters and non-consulters. A consulter was defined as a child who had sought the help of a medical practitioner at least once in the past year for recurrent abdominal pain. A detailed clinical, social and family history was obtained in all recruited children. Results. A total of 161 children were recruited: 78 (48.4%) consulters, 83 (51.6%) non-consulters. Of the consulters, 40 were boys, 38 were girls (male:female ratio = 1.1:1). The two sexes did not show a significant difference in prevalence of consulters (p=0.189). Of the ethnic groups, only Indians had a significantly higher likelihood to consult a doctor (Indians, p=0.006; Malays, p=0.742; Chinese, p=0.050). Younger children (under 12 years) had a significantly higher chance of having been brought to see a medical practitioner (p=0.014). Children in whom age of onset of abdominal pain was below ten years were also more likely to have been seen by a doctor (p=0.012). Children who had consulted a doctor were more likely to be missing school because of abdominal pain (p<0.001). Pain severity was not a significant factor (p=0.429). Multiple logistic regression analysis revealed that the only variable that remained significantly associated with health-care consultation was school absence (p=0.001). Conclusions. Children who saw their doctors for recurrent abdominal pain were also more likely to be those who missed school on account of abdominal pain. Following multiple regression analysis, other factors were no longer significant. AN - WOS:000168199500008 AU - Boey, C. C. M. AU - Goh, K. L. DA - Mar DO - 10.1016/s1590-8658(01)80069-4 IS - 2 N1 - Boey, CCM Goh, KL Boey, Christopher/D-4472-2012; Goh, Khean-Lee/B-6404-2009 PY - 2001 SN - 1125-8055 SP - 140-144 ST - Recurrent abdominal pain and consulting behaviour among children in a rural community in Malaysia T2 - Digestive and Liver Disease TI - Recurrent abdominal pain and consulting behaviour among children in a rural community in Malaysia UR - ://WOS:000168199500008 VL - 33 ID - 2854 ER - TY - JOUR AB - Aim: To look at the predictors of health-care consultation for recurrent abdominal pain among urban schoolchildren in Malaysia. Methods: Recurrent abdominal pain was defined as 'at least three episodes of abdominal pain, severe enough to affect a child's activities over a period longer than 3 months. A health-care consulter was defined as a child who had been brought to see a doctor regarding recurrent abdominal pain at least once in the past year. Children aged between 9 and 15 years were randomly chosen from schools in the city of Petaling Jaya, given questionnaires to fill in and interviewed to determine whether they fulfilled the above criteria for having symptoms of recurrent abdominal pain and for being a consulter. Bivariate analysis and multiple logistic regression analysis were performed on the data obtained. Results: One hundred and forty-three (9.61%) children fulfilled the criteria for recurrent abdominal pain out of a total of 1488 schoolchildren interviewed. There were 65 (45.5%) consulters and 78 (54.5%) non-consulters. Among the consulters, the male to female ratio was 1:1.4, while among the non-consulters, the ratio was 1:1.1. On bivariate analysis, the Chinese had a significantly lower likelihood to consult a doctor (P = 0.02), while the other two races did not show any increase in consultation (Malays, P = 0.08; Indians, P = 0.21). Among those with severe pain, there was a significantly higher prevalence of consulters (P < 0.01). Furthermore, those whose sleep was interrupted by abdominal pain were more likely to consult (P < 0.01). Children who had consulted a doctor were more likely to be missing school because of abdominal pain (P < 0.01). Following multiple logistic regression analysis, ethnicity was no longer a significant predictor. Conclusions: Approximately 45.5% of schoolchildren with recurrent abdominal pain in an urban setting were brought to see a doctor. Predictors of recent health-care consultation were school absence, pain severity and interruption of sleep caused by abdominal pain. (C) 2001 Blackwell Science Asia Pty Ltd. AN - WOS:000167702900007 AU - Boey, C. C. M. AU - Goh, K. L. DA - Feb DO - 10.1046/j.1440-1746.2001.02434.x IS - 2 N1 - Boey, CCM Goh, KL Boey, Christopher/D-4472-2012; Goh, Khean-Lee/B-6404-2009 PY - 2001 SN - 0815-9319 SP - 154-159 ST - Predictors of health-care consultation for recurrent abdominal pain among urban schoolchildren in Malaysia T2 - Journal of Gastroenterology and Hepatology TI - Predictors of health-care consultation for recurrent abdominal pain among urban schoolchildren in Malaysia UR - ://WOS:000167702900007 VL - 16 ID - 2856 ER - TY - JOUR AB - Objective: This systematic review explored the potential impact of parental multiple sclerosis on their offspring. It considered adjustment to parental multiple sclerosis at different developmental stages and the factors associated with good versus poor adjustment. Data sources: MEDLINE, EMBASE, PsycINFO, CINAHL and Web of Science were searched for studies on children with a parent with multiple sclerosis. Inclusion and exclusion criteria were formulated. Hand-searching journals and reference lists, contacting authors and multiple sclerosis societies for additional unpublished papers complemented the searches. Review methods: Twenty studies that satisfied the inclusion criteria were included. The research articles were ranked according to a quality assessment checklist and were categorized as good, medium or poor quality. Results: The review found good evidence to suggest that parental multiple sclerosis has a negative impact on children's social and family relationships and their psychological well-being. The review also identified potential factors associated with poor adjustment. These factors included parental negative emotions, increased illness severity, family dysfunction, children's lack of knowledge about the illness and lack of social support. Adolescent children also seemed to be more at risk for psychosocial problems than school-age children. Conclusions: There is good evidence that parental multiple sclerosis has a negative psychosocial impact on children, especially on adolescents. AN - WOS:000281352500002 AU - Bogosian, A. AU - Moss-Morris, R. AU - Hadwin, J. DA - Sep DO - 10.1177/0269215510367982 IS - 9 N1 - Bogosian, Angeliki Moss-Morris, Rona Hadwin, Julie Bogosian, Angeliki/0000-0003-1244-6387; Moss-Morris, Rona/0000-0002-2927-3446 1477-0873 PY - 2010 SN - 0269-2155 SP - 789-801 ST - Psychosocial adjustment in children and adolescents with a parent with multiple sclerosis: a systematic review T2 - Clinical Rehabilitation TI - Psychosocial adjustment in children and adolescents with a parent with multiple sclerosis: a systematic review UR - ://WOS:000281352500002 VL - 24 ID - 2537 ER - TY - JOUR AB - OBJECTIVE: To explore and describe older African Americans' patterns and perceptions of managing chronic osteoarthritis pain. METHODS: A convergent parallel mixed-methods design incorporating cross-sectional surveys and individual, semistructured interviews. SETTING: One hundred ten African Americans (≥50 years of age) with clinical osteoarthritis (OA) or provider-diagnosed OA from communities in northern Louisiana were enrolled. RESULTS: Although frequency varied depending on the severity of pain, older African Americans actively used an average of seven to eight self-management strategies over the course of a month to control pain. The average number of self-management strategies between high and low education and literacy groups was not statistically different, but higher-educated adults used approximately one additional strategy than those with high school or less. To achieve pain relief, African Americans relied on 10 self-management strategies that were inexpensive, easy to use and access, and generally perceived as helpful: over-the-counter (OTC) topicals, thermal modalities, land-based exercise, spiritual activities, OTC and prescribed analgesics, orthotic and assistive devices, joint injections, rest, and massage and vitamins. CONCLUSIONS: This is one of the first studies to quantitatively and qualitatively investigate the self-management of chronic OA pain in an older African American population that happened to be a predominantly higher-educated and health-literate sample. Findings indicate that Southern-dwelling African Americans are highly engaged in a range of different self-management strategies, many of which are self-initiated. Although still an important component of chronic pain self-management, spirituality was used by less than half of African Americans, but use of oral nonsteroidal anti-inflammatory drugs and opioids was relatively high. AD - Pain Research and Intervention Center of Excellence, The University of Florida, Gainesville, Florida. College of Nursing, The University of Iowa, Iowa City, Iowa, USA. AN - 30541043 AU - Booker, S. AU - Herr, K. AU - Tripp-Reimer, T. C2 - PMC7963201 DA - Aug 1 DO - 10.1093/pm/pny260 DP - NLM ET - 2018/12/13 IS - 8 KW - Administration, Topical Adrenal Cortex Hormones/therapeutic use *African Americans Aged Aged, 80 and over Analgesics/therapeutic use Analgesics, Opioid/therapeutic use Anti-Inflammatory Agents, Non-Steroidal/therapeutic use Arthralgia/*therapy *Attitude to Health Chronic Pain/*therapy Cross-Sectional Studies Educational Status Exercise Female Health Literacy Hot Temperature/therapeutic use Humans Hyaluronic Acid/therapeutic use Injections, Intra-Articular Louisiana Male Massage Middle Aged Nonprescription Drugs Orthotic Devices Osteoarthritis/*therapy Pain Management Qualitative Research Religion Rest Self-Help Devices Self-Management/*methods Spirituality Surveys and Questionnaires Viscosupplements/therapeutic use *African American *Aging *Blacks *Joint *Osteoarthritis *Pain *Self-Management LA - eng N1 - 1526-4637 Booker, Staja Herr, Keela Tripp-Reimer, Toni T32 NR011147/NR/NINR NIH HHS/United States T32 AG049673/AG/NIA NIH HHS/United States Journal Article Pain Med. 2019 Aug 1;20(8):1489-1499. doi: 10.1093/pm/pny260. PY - 2019 SN - 1526-2375 (Print) 1526-2375 SP - 1489-1499 ST - Patterns and Perceptions of Self-Management for Osteoarthritis Pain in African American Older Adults T2 - Pain Med TI - Patterns and Perceptions of Self-Management for Osteoarthritis Pain in African American Older Adults VL - 20 ID - 3598 ER - TY - JOUR AB - Objective: Minimally invasive repair of pectus excavatum (MIRPE) have gained support recently as it can be applied in both children and adults successfully. Our objective was to review minimally invasive repair of pectus excavatum in Marmara University School of Medicine. Patients and Methods: One hundred and sixty eight cases who had minimally invasive repair between August-2005 and November-2010 were reviewed retrospectively. Cases were evaluated according to demographics, surgical indication, form of deformity, concommitant anomalies, family history, previous corrections, number of bars, duration of the operation, concommitant procedures, pain management, peri-andpostoperative complications, bar removal, and patient satisfaction. Results: One hundred and forty one cases were male, 27 were female. Median age was 16. The deformity was symmetric in 110, asymmetric in 58 cases. The most common concommitant anomaly was scoliosis in 27 cases. 26 cases had a family history for deformity. 14 cases had a previous open repair. 1 bar in 105, 2 in 58, 3 in 5 cases were placed for correction. The median duration of the operation was 60 minutes. The most common perioperative complication was pneumothorax in 12 cases. The most common postoperative complication was wound infection in 8 cases. Bar removal was performed in 7 cases with only one recurrence. Quality-of-life questionnaires revealed that 94% of patients were satisfied with the treatment. Conclusion: This minimally invasive technique is a promising procedure for better cosmetic results and high levels of patient satisfaction. AN - WOS:000219993000007 AU - Bostanci, K. AU - Ozalper, H. AU - Yuksel, M. DO - 10.5472/mmj.2010.01752.1 IS - 1 N1 - Bostanci, Korkut Ozalper, Hakan Yuksel, Mustafa PY - 2011 SN - 1309-9469 SP - 38-43 ST - Minimally Invasive Repair Technique for Pectus Excavatum Deformity: The Marmara Experience T2 - Marmara Medical Journal TI - Minimally Invasive Repair Technique for Pectus Excavatum Deformity: The Marmara Experience UR - ://WOS:000219993000007 VL - 24 ID - 2522 ER - TY - JOUR AB - A 15-year-old competitive right-handed high school baseball pitcher experienced an acute onset of right elbow pain when throwing. He initially treated it conservatively with rest alone for 3 months, but on return to throwing, he was still experiencing pain. Radiographs revealed that he had a persistent olecranon physis. He proceeded with a trial of low-intensity pulsed ultrasound therapy and attained radiographic evidence of bony union at 7 months postinjury, thus avoiding surgical intervention. He returned to pitching competitively 9 months after injury without elbow pain. This is the first reported case of using ultrasound bone stimulation for treatment of a symptomatic persistent olecranon physis in a baseball pitcher. AD - Florida Spine Institute, Clearwater, Florida. University of Central Florida College of Medicine, Orlando, Florida. AN - 28654442 AU - Botwin, K. AU - McMillen, T. AU - Botwin, A. DA - Jul DO - 10.1097/jsm.0000000000000449 DP - NLM ET - 2017/06/28 IS - 4 KW - Adolescent Baseball/*injuries Elbow Joint/*injuries Epiphyses/pathology Growth Plate/pathology Humans Male Olecranon Process/*pathology *Pain Management *Ultrasonic Therapy Ultrasonic Waves LA - eng N1 - 1536-3724 Botwin, Kenneth McMillen, Thurston Botwin, Ariel Case Reports Journal Article United States Clin J Sport Med. 2018 Jul;28(4):e82-e84. doi: 10.1097/JSM.0000000000000449. PY - 2018 SN - 1050-642x SP - e82-e84 ST - Low-Intensity Pulsed Ultrasound Therapy for a Symptomatic Persistent Olecranon Physis in an Adolescent Baseball Pitcher T2 - Clin J Sport Med TI - Low-Intensity Pulsed Ultrasound Therapy for a Symptomatic Persistent Olecranon Physis in an Adolescent Baseball Pitcher VL - 28 ID - 3745 ER - TY - JOUR AB - Background Although increasing participation in physical activities has significant health benefits, there are no guidelines to help professionals decide when it is safe to return to activity after injury. Objective To examine the specific criteria (eg, strength, pain) that expert sport medicine clinicians use for return to activity decisions in children with musculoskeletal injuries. Methods The authors conducted an online cross-sectional survey of certified Canadian sport medicine doctors (MDs) and sport rehabilitation specialists (physiotherapists (PTs) or athletic therapists (ATs)). The authors asked how they would measure each of the following signs in the context of a knee injury: sport-specific skills, pain, swelling, strength, range of motion (ROM) and balance. Clinicians also ranked the importance of each sign with respect to influencing their recommendations for each of five clinical vignettes. Results The overall response rate was 33.6% (464/1380) with similar rates for each profession. For each clinical sign, all three professions preferred the same measure to determine readiness to return to play: standardised testing for sport-specific skills, impact on function for pain, palpation for swelling, manual muscle testing for strength, visual inspection for ROM and standing on one leg with eyes closed for balance. Regarding importance of specific signs for return to activity, all professions had similar responses for one vignette, but MDs differed from PTs and ATs for the remaining four. Finally, pain was ranked as the no 1 or 2 most important sign in all five vignettes by 41.0% of MDs, 18.1% of ATs and 11.3% of PTs, whereas sport-specific skills was chosen by 9.6% MDs, 12.0% ATs and 16.1% PTs. Conclusion Our results provide the foundation for future work leading towards the development of interdisciplinary consensus guidelines. AN - WOS:000296061300013 AU - Boudier-Reveret, M. AU - Mazer, B. AU - Feldman, D. E. AU - Shrier, I. DA - Nov DO - 10.1136/bjsm.2009.071233 IS - 14 N1 - Boudier-Reveret, Mathieu Mazer, Barbara Feldman, Debbie Ehrmann Shrier, Ian Boudier-Reveret, Mathieu/X-1525-2018; Shrier, Ian/AAI-6502-2020 Boudier-Reveret, Mathieu/0000-0003-0259-8520; Shrier, Ian/0000-0001-9914-3498 PY - 2011 SN - 0306-3674 SP - 1137-1143 ST - Practice management of musculoskeletal injuries in active children T2 - British Journal of Sports Medicine TI - Practice management of musculoskeletal injuries in active children UR - ://WOS:000296061300013 VL - 45 ID - 2472 ER - TY - JOUR AB - Parental encouragement of illness behavior is hypothesized to correlate with psychosocial dysfunction in adolescents with chronic illness. To explore this hypothesis, adolescents aged 11 to 17 years with chronic fatigue syndrome (CFS) (n = 10), juvenile rheumatoid arthritis (JRA) (n = 16), and healthy adolescents (n = 14) were recruited for the study. Measures included the Achenbach parent and youth self report forms, the Family Adaptability and Cohesion Evaluation Scale-ii (FACES II), the Children's Depression Rating Scale, and number of days absent from school. The Illness Behavior Encouragement Scale (IBES) generated measures of parental reinforcement of illness behavior. As predicted, the teens with CFS scored statistically higher on measures of depression, total competence, and number of days of school missed in the previous 6 months (mean = 40). Children with JRA scored significantly lower than the CFS group on the measure of parental reinforcement of illness behavior. The healthy group produced intermediate scores. Results and implications for future clinical and research activity are discussed. AN - WOS:000089857900003 AU - Brace, M. J. AU - Smith, M. S. AU - McCauley, E. AU - Sherry, D. D. DA - Oct DO - 10.1097/00004703-200010000-00003 IS - 5 N1 - Brace, MJ Smith, MS McCauley, E Sherry, DD PY - 2000 SN - 0196-206X SP - 332-339 ST - Family reinforcement of illness behavior: A comparison of adolescents with chronic fatigue syndrome, juvenile arthritis, and healthy controls T2 - Journal of Developmental and Behavioral Pediatrics TI - Family reinforcement of illness behavior: A comparison of adolescents with chronic fatigue syndrome, juvenile arthritis, and healthy controls UR - ://WOS:000089857900003 VL - 21 ID - 2863 ER - TY - JOUR AB - This study aimed to describe the outcomes of children with sickle cell disease (SCD) after discharge from medical care for vaso-occlusive painful events and to test the hypothesis that older age, longer length of hospital stay, and a history of frequent vaso-occlusive painful events will be associated with poor outcomes. Children aged 2-18 years with SCD treated in the emergency department or inpatient unit for a painful event were contacted after discharge to assess: days of pain, days of functional limitations for the child, and days of work/school absenteeism for the caregiver. Descriptive statistics were applied and multivariate logistic regression examined the association between the predictors and outcomes. Fifty-eight children were enrolled (mean age 10.8 +/- 4.8 years, 53.5% female). Postdischarge, 46.5% of children reported three or more days of pain, 54.3% had two or more days of functional limitations, and 24.3% of caregivers missed two or more days of work/school. Children with three or more prior painful events had increased odds of a poor outcome postdischarge (OR 1.79; 95% CI = 1.026, 3.096). In conclusion, acute vaso-occlusive painful events impact the lives of children with SCD and their caregivers, even after discharge to home. AN - WOS:000262826400018 AU - Brandow, A. M. AU - Brousseau, D. C. AU - Panepinto, J. A. DA - Mar DO - 10.1111/j.1365-2141.2008.07512.x IS - 5 N1 - Brandow, Amanda M. Brousseau, David C. Panepinto, Julie A. 1365-2141 PY - 2009 SN - 0007-1048 SP - 782-788 ST - Postdischarge pain, functional limitations and impact on caregivers of children with sickle cell disease treated for painful events T2 - British Journal of Haematology TI - Postdischarge pain, functional limitations and impact on caregivers of children with sickle cell disease treated for painful events UR - ://WOS:000262826400018 VL - 144 ID - 2607 ER - TY - JOUR AB - Musculoskeletal pain is exceedingly common in young adults. With the aim of studying these symptoms in schoolchildren, a questionnaire survey was carried out among children 8, 11, 13 and 17 years old. The prevalence of back pain and headaches in 1,245 schoolchildren was studied, Twenty-nine per cent of the students reported back pain and 48% headache. In all age groups studied, both back pain and headaches were more common among girls than boys. Girls also reported more frequent symptoms than boys. In a longitudinal study 471 schoolchildren were asked a second time 2 years later. Nine per cent reported back pain and 30% headache in both surveys, Five per cent reported both back pain and headache on both occasions, Despite the reported symptoms most of the pupils did not report health problems. However, pupils with reported pain on both occasions may constitute a risk group for future chronic pain. There were statistically significant relationships between social, psychological and emotional factors and reported symptoms. No relationship between physical factors and reported symptoms were noted. The observed relationships are not proof of causal relations but did indicate areas of problems which make interventions targeting pupils at risk an appropriate measure. AN - WOS:A1994QB74500005 AU - Brattberg, G. DA - Dec DO - 10.1007/bf00433372 N1 - Brattberg, g Satellite Symposium of the 7th World Congress on Pain Aug 17-19, 1993 Lund univ hosp, lund, sweden 1 PY - 1994 SN - 0962-9343 SP - S27-S31 ST - THE INCIDENCE OF BACK PAIN AND HEADACHE AMONG SWEDISH SCHOOL-CHILDREN T2 - Quality of Life Research TI - THE INCIDENCE OF BACK PAIN AND HEADACHE AMONG SWEDISH SCHOOL-CHILDREN UR - ://WOS:A1994QB74500005 VL - 3 ID - 2944 ER - TY - JOUR AB - DESIGN: In a longitudinal study, 335 children ages 8, 11 and 14, first studied in 1989 were followed-up on two occasions in 1991 and 2002. The subjects filled in questionnaires on pain, the first two times in school, the last as a postal survey. PURPOSES: To determine if headache and back pain during the school years were transitory or if they grew into pain problems in adulthood; to determine predictors of pain. RESULTS: In the 2002 study, 59% of the women and 39% of the men reported pain at 21, 24 and 27 years. A total of 68 (52 women, 16 men) or 20% of the subjects reported pain symptoms in all three studies. The cumulative incidence rate for the presence of pain in the cohort studied was 31% for 1989-2002 and 43% for 1991-2002. Four of the 10 individuals with pain also reported signs of stress. Three predictors were found: reported back pain in 8-14-year-olds (p < 0.0001); reported headaches once a week or more in the same age group (p < 0.0001); and a positive response in the ages 10-16 to the question: "Do you often feel nervous?" (OR=2.1, 95% CI 1.3-3.4). When adjusted for age, sex and all psychosocial risk determinants studied in multiple logistic regression, a positive answer to this question was a significant predictor of pain in young adulthood. A positive response by the 10-16-year-olds to "Do you find it difficult to describe your feelings?" was a predictor of pathological anxiety in early adulthood, but stress perceived in childhood/adolescence did not predict future pain or stress. CONCLUSIONS: Since pain reports in childhood and early adolescence seem to be associated with the report of pain in early adulthood, more attention should be given to the way ill-health is managed in adolescence in this vulnerable group. AU - Brattberg, Gunilla DA - 2004/06// DO - 10.1016/j.ejpain.2003.08.001 DP - PubMed IS - 3 J2 - Eur J Pain KW - Adolescent Adult Age Factors Causality Child Chronic Disease Comorbidity Female Follow-Up Studies Headache Health Status Humans Incidence Longitudinal Studies Male Pain Pain Measurement Predictive Value of Tests Quality of Life Sex Factors Stress, Psychological Surveys and Questionnaires Sweden LA - eng PY - 2004 SN - 1090-3801 SP - 187-199 ST - Do pain problems in young school children persist into early adulthood? T2 - European Journal of Pain (London, England) TI - Do pain problems in young school children persist into early adulthood? A 13-year follow-up UR - http://www.ncbi.nlm.nih.gov/pubmed/15109969 VL - 8 ID - 127 ER - TY - JOUR AB - We estimated the prevalence of chronic diseases and other health problems reported by adolescents in relation to social and demographic variables and nutritional status. This cross-sectional population-based survey analyzed data from the Health Survey in Campinas, São Paulo State, Brazil, 2008. We used descriptive statistics and associations between variables with the chisquare test. Prevalence of chronic diseases among adolescents was 19.17%, with asthma showing the highest prevalence (7.59%), followed by heart disease (1.96%), hypertension (1.07%), and diabetes 0.21%. Prevalence rates were 61.53% for health problems, 40.39% for allergy, and 24.83% for frequent headache or migraine. After multivariate analysis using Poisson regression, the factors associated with chronic disease were age 15 to 19 years (PR = 1.38), not attending school (PR = 1.46), having children (PR = 1.84), and obesity (PR = 1.54). Female gender (PR = 1.12) was statistically associated with health problems. The study illustrates that adolescence is a life stage in which chronic disease and health problems can occur. AD - Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, Brasil. AN - 24068232 AU - Braz, M. AU - Barros Filho, A. A. AU - Barros, M. B. DA - Sep DO - 10.1590/0102-311x00169712 DP - NLM ET - 2013/09/27 IS - 9 KW - Adolescent Asthma/epidemiology Brazil/epidemiology Cardiovascular Diseases/epidemiology Child Chronic Disease/classification/*epidemiology Epidemiologic Methods Female Headache/epidemiology Humans Male Migraine Disorders/epidemiology Pregnancy Socioeconomic Factors Urban Population Young Adult LA - por N1 - 1678-4464 Braz, Marici Barros Filho, Antonio A Barros, Marilisa B A English Abstract Journal Article Research Support, Non-U.S. Gov't Brazil Cad Saude Publica. 2013 Sep;29(9):1877-88. doi: 10.1590/0102-311x00169712. OP - Saúde dos adolescentes: um estudo de base populacional em Campinas, São Paulo, Brasil. PY - 2013 SN - 0102-311x SP - 1877-88 ST - [Adolescent health: a population-based study in Campinas, São Paulo State, Brazil] T2 - Cad Saude Publica TI - [Adolescent health: a population-based study in Campinas, São Paulo State, Brazil] VL - 29 ID - 3385 ER - TY - JOUR AB - Background: Children with severe cognitive impairments are believed to suffer pain frequently. Objective: To document the frequency, duration, and intensity of pain experienced by children with severe cognitive impairments. Design: Cohort study using surveys during 1 year. Setting: Tertiary-care pediatric center for 3 provinces in eastern Canada. Participants: Caregivers of 94 children and adolescents with moderate to profound mental retardation, aged 3 to 18 years (mean age, 10.1 years [SD, 4.3 years]). Forty-four children had cerebral palsy and 59 had a seizure disorder; 83 lived with family, and 11 in group homes. Results: A total of 406 episodes of pain occurred. During a 4-week period, 73 children (78%) experienced pain at least once, and 58 (62%) had nonaccidental pain. Accidental pain was most frequent (n=28 [30%]), followed by gastrointestinal tract (n=21 [22%]), infection (n=19 [20%]), and musculoskeletal (n=18 [19%]) pain. Each week, 33 to 49 children (35%-52%) had pain. Mean pain duration was longer than 9 hours per week (SD, 1.7-2.4 hours). Mean intensity was 6.1 (SD, 2.2) for nonaccidental pain and 3.8 (SD, 2.1) for accidental pain. Children with the fewest abilities had more nonaccidental pain (F(4,89)= 3.7; P=.007), and children with greater motor abilities had more accidental pain (F(4,89)= 2.8; P=.03). Pain did not vary with demographic characteristics. Conclusions: Children with severe cognitive impairments experience pain frequently, mostly not due to accidental injury. Children with the fewest abilities experience the most pain. AN - WOS:000186959800017 AU - Breau, L. M. AU - Camfield, C. S. AU - McGrath, P. J. AU - Finley, G. A. DA - Dec DO - 10.1001/archpedi.157.12.1219 IS - 12 N1 - Breau, LM Camfield, CS McGrath, PJ Finley, GA Meeting of the Canadian-Pain-Society May 22, 2003 Toronto, canada Canadian Pain Soc McGrath, Patrick J/F-4326-2011; Finley, Allen/AAD-7583-2020 Finley, Allen/0000-0003-4579-7749; McGrath, Patrick/0000-0002-9568-2571 PY - 2003 SN - 1072-4710 SP - 1219-1226 ST - The incidence of pain in children with severe cognitive impairments T2 - Archives of Pediatrics & Adolescent Medicine TI - The incidence of pain in children with severe cognitive impairments UR - ://WOS:000186959800017 VL - 157 ID - 2800 ER - TY - JOUR AB - OBJECTIVES: Non-specific chronic low back pain (NSCLBP): Which conservative therapy shows an evident effectiveness - A review of the current literature. MATERIALS AND METHODS: Our results are based on literature reviews of current randomised control studies, reviews and meta-analysis drawn from the Cochrane Library and Medline-Database between the years 2004 until 2015. German and English Studies were included. We focused on different conservative Treatments of NSCLBP, which are listed at, the NVL-Guidelines. Based on the given evidence we evaluated their effectiveness. RESULTS: As part of the review we identified 4657 Publications, 85 were included in this study. Therapeutic options such as bed rest, TENS, Massage, Spine Supports, Back Schools and Antidepressants showed no evident effectiveness. Injections, NSAR analgesic therapy, Thermotherapy and Opioid analgesic therapy indicated a short-time effectiveness. A long term success (> 6 weeks) however, can not be shown. Only the Movement therapy can, in the summation of the included studies, postulate an evident (Evidence Level I) long-term effect treating NSCLBP. Only a few therapy options indicate a significant evident effectiveness for treating NSCLBP conservatively. At short notice methods such as injection therapy, thermo-therapy and analgesic therapies with NSAR and/or opioids help coping the acute phase. In the long term only movement therapy seems to provide an evident effectiveness. In the case of therapy-refractory NSCLBP a multimodal therapy should be considered. AD - Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Köln, Joseph-Stelzmann-Str.24, 50931, Köln, Deutschland. jan.bredow@uk-koeln.de. Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Köln, Joseph-Stelzmann-Str.24, 50931, Köln, Deutschland. AN - 27075679 AU - Bredow, J. AU - Bloess, K. AU - Oppermann, J. AU - Boese, C. K. AU - Löhrer, L. AU - Eysel, P. DA - Jul DO - 10.1007/s00132-016-3248-7 DP - NLM ET - 2016/04/15 IS - 7 KW - Adolescent Adult Age Distribution Aged Aged, 80 and over Analgesics/*therapeutic use Chronic Pain/diagnosis/*epidemiology/*therapy Combined Modality Therapy/statistics & numerical data Evidence-Based Medicine Female Humans Hyperthermia, Induced/statistics & numerical data Low Back Pain/diagnosis/*epidemiology/*therapy Male Massage/statistics & numerical data Middle Aged Musculoskeletal Manipulations/*statistics & numerical data Pain Measurement/statistics & numerical data Prevalence Risk Factors Sex Distribution Transcutaneous Electric Nerve Stimulation/*statistics & numerical data Treatment Outcome Young Adult Analgesia Conservative therapy Low back pain Movement therapy Pain, chronic LA - ger N1 - 1433-0431 Bredow, J Bloess, K Oppermann, J Boese, C K Löhrer, L Eysel, P Journal Article Meta-Analysis Review Systematic Review Germany Orthopade. 2016 Jul;45(7):573-8. doi: 10.1007/s00132-016-3248-7. OP - Konservative Therapie beim unspezifischen, chronischen Kreuzschmerz : Evidenz der Wirksamkeit - eine systematische Literaturanalyse. PY - 2016 SN - 0085-4530 SP - 573-8 ST - [Conservative treatment of nonspecific, chronic low back pain : Evidence of the efficacy - a systematic literature review] T2 - Orthopade TI - [Conservative treatment of nonspecific, chronic low back pain : Evidence of the efficacy - a systematic literature review] VL - 45 ID - 2964 ER - TY - JOUR AB - OBJECTIVE: Functional abdominal pain is a common symptom in children and adolescents. Three years ago, we investigated the experiences among parents whose children had chronic abdominal pain but no somatic diagnosis. The aim of the present follow-up study was to explore those families' current situations. DESIGN: Interviews with open questions about the families' current pain situations were carried out by the first author. Interviews were audio-recorded and transcribed, and subsequently analysed using descriptive content analysis. SETTING: Urban and rural areas in two municipalities in Southern Norway. PARTICIPANTS: Parents of children with abdominal pain who had been referred to a local hospital by their general practitioner and had been discharged without a somatic diagnosis. Fifteen parents of 14 children aged 8-17 years who had also been interviewed in 2016. RESULTS: Nine of the children had recovered from their abdominal pain. During the pain period, the parents reported frustration with not having a diagnosis nor a specific treatment for their child's abdominal pain. The siblings in some families received less attention and were afraid that something serious might happen to their sister or brother. The parents wished that their child's school cared more about the child when they had weeks of absence. All parents maintained that their child's pain was physical, although they thought that psychological aspects might have influenced the symptoms. The parents stated that they, as well as their children, needed guidance from professionals to understand the complex pain situation. AD - General Practice Research Unit, Department of Health and Society, University of Oslo, Oslo, Norway. General Practice Research Unit, Department of Health and Society, University of Oslo, Oslo, Norway abrodwa@online.no. AN - 32868359 AU - Brekke, M. AU - Brodwall, A. C2 - PMC7462228 DA - Aug 30 DO - 10.1136/bmjopen-2020-037288 DP - NLM ET - 2020/09/02 IS - 8 KW - *Abdominal Pain Adolescent Child Follow-Up Studies Humans Male Norway Parent-Child Relations *Parents *Professional-Family Relations Qualitative Research *paediatric gastroenterology *pain management *qualitative research LA - eng N1 - 2044-6055 Brekke, Mette Orcid: 0000-0003-3454-2329 Brodwall, Anne Journal Article Research Support, Non-U.S. Gov't BMJ Open. 2020 Aug 30;10(8):e037288. doi: 10.1136/bmjopen-2020-037288. PY - 2020 SN - 2044-6055 SP - e037288 ST - Understanding parents' experiences of disease course and influencing factors: a 3-year follow-up qualitative study among parents of children with functional abdominal pain T2 - BMJ Open TI - Understanding parents' experiences of disease course and influencing factors: a 3-year follow-up qualitative study among parents of children with functional abdominal pain VL - 10 ID - 3851 ER - TY - JOUR AB - Many children report chronic abdominal pain that is severe and disruptive to normal lifestyle and schooling. Assessment and management depends on indentifying those with underlying organic disease, such as chronic infection, celiac disease or inflammatory bowel disease, but avoiding unnecessary invasive investigations. In those with a functional gut disorder, the aim of therapy is reassurance, a return to normal activity and symptom control. We address the evidence for the use of investigative and management strategies in situations where recurrent abdominal pain is likely to be a functional disorder. Epidemiological studies of European and American populations show that organic causes are uncommon, and that chronic abdominal pain is a risk factor for functional gut disorders in adulthood. There is a paucity of high quality therapeutic trials, none showing conclusive evidence of benefit. Psychological interventions, such as cognitive behavioral and family therapy are effective, reducing symptoms and improving school attendance. Asian studies suggest gastrointestinal infection, such as giardiasis, are common causes of recurrent abdominal pain, but that functional abdominal pain is also prevalent. AN - WOS:000266355900001 AU - Bremner, A. R. AU - Sandhu, B. K. DA - May IS - 5 N1 - Bremner, A. R. Sandhu, B. K. 0974-7559 PY - 2009 SN - 0019-6061 SP - 375-379 ST - Recurrent Abdominal Pain in Childhood: The Functional Element T2 - Indian Pediatrics TI - Recurrent Abdominal Pain in Childhood: The Functional Element UR - ://WOS:000266355900001 VL - 46 ID - 2603 ER - TY - JOUR AB - BACKGROUND: Lower back pain (LBP) is ranked first as a cause of disability and inability to work, and is expected to affect up to 90% of the worlds population at some point in their lifetime. The annual first time incidence of LBP is 5%, and the annual prevalence (i.e. those suffering at time of questioning) is between 15 and 63%. Prospective studies demonstrate that low back problems do not display a six-week spontaneous recovery pattern, as was once believed. The condition is regularly seen to worsen over time, becoming a chronic disorder, influenced by both physical and psychosocial factors. METHODS: The current study assessed the level of LBP amongst students engaged in educational programs that were physically demanding, and its influence on lower back problems. A 1-year retrospective questionnaire consisting of 37 closed, open and multi-choice questions was designed to ascertain self-reported information on the occurrence, cause and type of LBP. Treatment, care seeking and general knowledge regarding LBP were also recorded. Students were enrolled in BSc Equine Science, BSc Physical Education and BSc Sports & Exercise Science degree programs and a total number of 188 valid questionnaires were collected. RESULTS: The self reported, anthropometrical data for participants in this study are: age 20.9 +/- 2.7 yrs; height 171.8 +/- 9.3 cm; weight 66.7 +/- 10.4 kg; female 64% (n = 120), male 36% (n = 68). The overall self reported prevalence of LBP was 32% (n = 61). Within the LBP population, 77% reported their problem as recurring. Two factors showed significance as having an influence on LBP. They were age (21.6 +/- 3.5 yrs, p = 0.005) and hours of personal training physical activity (14.0 +/- 8.2 hrs per week, p = 0.02). LBP sufferers also displayed poor management of their condition and an interest in education and treatment of their problem. CONCLUSION: The current study revealed high prevalence of LBP consistent with that of the literature, and unveiled a recurrence rate and behavioral habits of sufferers, which are warning signs of a more chronic state to come. Novel data presented here offers strong support for the need for prospective injury tracking, plus educational intervention and treatment aimed at prevention of LBP. AD - Department of Physical Education and Sports Sciences, University of Limerick, Limerick, Ireland. graham.brennan@ul.ie AN - 17631036 AU - Brennan, G. AU - Shafat, A. AU - Mac Donncha, C. AU - Vekins, C. C2 - PMC1950501 DA - Jul 13 DO - 10.1186/1471-2474-8-67 DP - NLM ET - 2007/07/17 KW - Adult Age Factors Animal Husbandry/*education Anthropometry Chronic Disease Exercise Female Humans Ireland/epidemiology Low Back Pain/*epidemiology/etiology Male Patient Acceptance of Health Care/statistics & numerical data Patient Education as Topic *Physical Education and Training *Physical Exertion Prevalence Retrospective Studies Sampling Studies Sports/*education Students/psychology Surveys and Questionnaires Universities/statistics & numerical data LA - eng N1 - 1471-2474 Brennan, Graham Shafat, Amir Mac Donncha, Ciarán Vekins, Carmel Journal Article BMC Musculoskelet Disord. 2007 Jul 13;8:67. doi: 10.1186/1471-2474-8-67. PY - 2007 SN - 1471-2474 SP - 67 ST - Lower back pain in physically demanding college academic programs: a questionnaire based study T2 - BMC Musculoskelet Disord TI - Lower back pain in physically demanding college academic programs: a questionnaire based study VL - 8 ID - 3546 ER - TY - JOUR AB - OBJECTIVES: The aim of the study was to assess the differences in reported pain from venipuncture comparing liposomal 4% lidocaine with placebo cream in a pediatric population. Other factors assessed were patient anxiety, difficulty of venipuncture, and history of venipuncture. METHODS: A prospective, randomized, double-blind, placebo control study design was used in which subjects were assigned to receive either liposomal 4% lidocaine or placebo cream. The study population consisted of pediatric patients aged 5 to 18 years old who presented to 1 site of a multisite, academic, community emergency department. Once subjects had consented and randomized, the liposomal 4% lidocaine or placebo cream was applied for 15 minutes under occlusion. A 6-point validated FACES pain scale was used to evaluate each patient's level of pain during venipuncture. Patient anxiety was evaluated using a 100-mm visual analogue scale before, during, and after the venipuncture. Heart rate was captured as an indirect measurement of pain. RESULTS: There were no significant differences between the study and placebo groups (P > .05) in mean levels of patient ratings of anxiety, patient heart rate, or the patient's mean rating of pain before, during, or after the venipuncture procedure. There was an association between increased anxiety with an increase in venipuncture pain and an inverse association between age and pain. CONCLUSION: Topical liposomal 4% lidocaine cream in this case did not prove to be effective with a 15-minute dwell time under occlusion because there were no differences in pain between study groups. AD - Inpatient Pediatrics, Division of General Pediatrics, Case Management, Lehigh Valley Health Network, Allentown, PA, USA. AN - 22809774 AU - Brenner, S. M. AU - Rupp, V. AU - Boucher, J. AU - Weaver, K. AU - Dusza, S. W. AU - Bokovoy, J. DA - Jan DO - 10.1016/j.ajem.2012.05.003 DP - NLM ET - 2012/07/20 IS - 1 KW - Administration, Topical Adolescent Anesthetics, Local/*administration & dosage Child Child, Preschool Double-Blind Method Female Heart Rate Humans Lidocaine/*administration & dosage Linear Models Liposomes Male Pain/*etiology/*prevention & control Pain Management/*methods Pain Measurement Phlebotomy/*adverse effects/methods Placebos Prospective Studies Treatment Outcome LA - eng N1 - 1532-8171 Brenner, Scott M Rupp, Valerie Boucher, Jenny Weaver, Kevin Dusza, Stephen W Bokovoy, Joanna Journal Article Randomized Controlled Trial United States Am J Emerg Med. 2013 Jan;31(1):20-5. doi: 10.1016/j.ajem.2012.05.003. Epub 2012 Jul 16. PY - 2013 SN - 0735-6757 SP - 20-5 ST - A randomized, controlled trial to evaluate topical anesthetic for 15 minutes before venipuncture in pediatrics T2 - Am J Emerg Med TI - A randomized, controlled trial to evaluate topical anesthetic for 15 minutes before venipuncture in pediatrics VL - 31 ID - 3665 ER - TY - JOUR AB - Menometrorrhagia is a common symptom in adolescents. It is idiopathic in most cases. In case of menometrorrhagia, it is necessary to exclude a pregnancy, a disorder of hemostasis, particularly the von Willebrand disease, as it represents the most common inherited disorder, and more rarely a chronic disease or an endocrinopathy. History of the bleedings, menstrual blood loss quantification by the Higham score and tolerance of the bleedings (blood pressure) should be evaluated. Laboratory testing includes hCG, ferritin level, a complete blood count, a prothrombin time, an activated partial thromboplastin. Management of menometrorrhagia is related to the severity of the blood loss. It associates antifibrinolytics or non-steroidal anti-inflammatory agents (NSAIDS) with hormonal treatments, such as estrogen-progestin oral contraceptive pill or cyclic oral progestins. Primary or functional dysmenorrhea concerns 40 to 90% of the teenagers and represents a frequent cause of school absenteeism. Management of primary dysmenorrhea is primarily based on a treatment by NSAIDS. In case of its inefficacy or if contraception is needed hormonal treatments, such as estrogen-progestin combined pill should be prescribed. It is very important when pelvic pain is chronic and not soothed by simple medications to look for a secondary dysmenorrhea, mainly endometriosis. In such cases, pelvic magnetic resonance imaging should be performed. (C) 2013 Elsevier Masson SAS. All rights reserved. AN - WOS:000323141700019 AU - Bricaire, L. AU - Laroche, E. AU - Christin-Maitre, S. DA - Aug DO - 10.1016/j.arcped.2013.04.010 IS - 8 N1 - Bricaire, L. Laroche, E. Christin-Maitre, S. 1769-664x PY - 2013 SN - 0929-693X SP - 910-914 ST - Meno-metrorrhagia, dysmenorrhea in adolescents T2 - Archives De Pediatrie TI - Meno-metrorrhagia, dysmenorrhea in adolescents UR - ://WOS:000323141700019 VL - 20 ID - 2360 ER - TY - JOUR AB - CONTEXT: Behavioural interventions are used to prevent, manage and treat a wide variety of conditions including obesity, diabetes, chronic pain, asthma and emotional difficulties. There has been inadequate attention to the delivery of behavioural interventions to younger children (5-11 years old). OBJECTIVE: Our objectives were to describe the characteristics of behavioural interventions for children aged 5-11 years. DATA SOURCES: We searched five databases: CINAHL, EMBASE, PsycINFO, MEDLINE and Cochrane Library, from January 2005 to August 2019. STUDY SELECTION: The inclusion criteria were (1) children aged 5-11, (2) cognitive and/or behavioural interventions, (3) randomised controlled trials and (4) 2005 onward. Two researchers independently identified studies for inclusion. DATA EXTRACTION: Two researchers independently extracted data from eligible papers. RESULTS: The search identified 10 541 papers. We extracted information on 117 interventions (from 152 papers). Many of the interventions were categorised as complex. This was particularly true for clinical populations; 78.7% were delivered to both the child and parent, and 33.9% took place across multiple settings, typically health and school settings. Most (70.9%) were 'First Wave' (behavioural) interventions, and few (4.3%) were 'Third Wave' (characterised by metacognition, acceptance and mindfulness). Thirty-nine per cent used interactive techniques (play, arts, story and/or games). Purely digital and paper-based interventions were rare, but around a third used these tools as supplements to face-face delivery. There were differences in interventions for younger (5-7 years) and older (8-11 years) children. CONCLUSIONS: Interventions designed and delivered to children should be developmentally sensitive. This review highlights characteristics of interventions delivered to children 5-11 years old: the involvement of the child's parent, using behavioural (rather than cognitive) modalities, using interactive techniques and some interventions were delivered across multiple settings. AD - Centre for Academic Child Health, Bristol Medical School, University of Bristol, Bristol, UK. Department of Psychology, University of Bath, Bath, Somerset, UK. Bristol Medical School, University of Bristol, Bristol, UK. AN - 31909219 AU - Brigden, A. AU - Parslow, R. M. AU - Linney, C. AU - Higson-Sweeney, N. AU - Read, R. AU - Loades, M. AU - Davies, A. AU - Stoll, S. AU - Beasant, L. AU - Morris, R. AU - Ye, S. AU - Crawley, E. C2 - PMC6937047 DO - 10.1136/bmjpo-2019-000543 DP - NLM ET - 2020/01/08 IS - 1 KW - child psychology comm child health general paediatrics health service paediatric practice LA - eng N1 - 2399-9772 Brigden, Amberly Orcid: 0000-0002-7958-7881 Parslow, Roxanne Morin Linney, Catherine Higson-Sweeney, Nina Read, Rebecca Loades, Maria Davies, Anna Stoll, Sarah Beasant, Lucy Morris, Richard Ye, Siyan Crawley, Esther Orcid: 0000-0002-2521-0747 DRF-2016-09-021/DH_/Department of Health/United Kingdom DRF-2017-10-169/DH_/Department of Health/United Kingdom SRF-2013-06-013/DH_/Department of Health/United Kingdom Journal Article BMJ Paediatr Open. 2019 Dec 10;3(1):e000543. doi: 10.1136/bmjpo-2019-000543. eCollection 2019. PY - 2019 SN - 2399-9772 SP - e000543 ST - How are behavioural interventions delivered to children (5-11 years old): a systematic mapping review T2 - BMJ Paediatr Open TI - How are behavioural interventions delivered to children (5-11 years old): a systematic mapping review VL - 3 ID - 4213 ER - TY - JOUR AB - Psychosomatic symptoms are by definition clinical symptoms with no underlying organic pathology. Common symptoms seen in pediatric age group include abdominal pain, headaches, chest pain, fatigue, limb pain, back pain, worry about health and difficulty breathing. These, more frequently seen symptoms should be differentiated from somatoform or neurotic disorders seen mainly in adults. The prevalence of psychosomatic complaints in children and adolescents has been reported to be between 10 and 25%. These symptoms are theorized to be a response to stress. Potential sources of stress in children and adolescents include schoolwork, family problems, peer pressure, chronic disease or disability in parents, family moves, psychiatric disorder in parents and poor coping abilities. Characteristics that favour psychosomatic basis for symptoms include vagueness of symptoms, varying intensity, inconsistent nature and pattern of symptoms, presence of multiple symptoms at the same time, chronic course with apparent good health, delay in seeking medical care, and lack of concern on the part of the patient. A thorough medical and psychosocial history and physical examination are the most valuable aspects of diagnostic evaluation. Organic etiology for the symptoms must be ruled out. Appropriate mental health consultation should be considered for further evaluation and treatment. AD - Overlook Hospital Children's Medical Centre, Summit, New Jersey and Michigan State University, Kalamazoo Centre for Medical Studies, Kalamazoo, Michigan, USA. AN - 11519281 AU - Brill, S. R. AU - Patel, D. R. AU - MacDonald, E. DA - Jul DO - 10.1007/bf02752270 DP - NLM ET - 2001/08/25 IS - 7 KW - Abdominal Pain/*diagnosis Adolescent Child Diagnosis, Differential Female Headache/*diagnosis Humans Hyperventilation/*diagnosis Incidence Male Psychophysiologic Disorders/*diagnosis/epidemiology Risk Assessment LA - eng N1 - Brill, S R Patel, D R MacDonald, E Case Reports Journal Article Review India Indian J Pediatr. 2001 Jul;68(7):597-603. doi: 10.1007/BF02752270. PY - 2001 SN - 0019-5456 (Print) 0019-5456 SP - 597-603 ST - Psychosomatic disorders in pediatrics T2 - Indian J Pediatr TI - Psychosomatic disorders in pediatrics VL - 68 ID - 3828 ER - TY - JOUR AB - BACKGROUND: Headaches affect most children and rank third among illness-related causes of school absenteeism. Although the short-term outcome for most children appears favorable, few studies have reported long-term outcome. OBJECTIVE: To evaluate the long-term prognosis of childhood headaches 20 years after initial diagnosis in a cohort of Atlantic Canadian children who had headaches diagnosed in 1983. METHODS: Ninety-five patients with headaches who consulted 1 of the authors in 1983 were previously studied in 1993. The 77 patients contacted in 1993 were followed up in 2003. A standardized interview protocol was used. RESULTS: Sixty (78%) of 77 patients responded (60 of the 95 of the original cohort). At 20-year follow-up, 16 (27%) were headache free, 20 (33%) had tension-type headaches, 10 (17%) had migraine, and 14 (23%) had migraine and tension-type headaches. Having more than 1 headache type was more prevalent than at diagnosis or initial follow-up (P<.001), and headache type varied across time. Of those with headaches at follow-up, 80% (35/44) described their headaches as moderate or severe, although an improvement in headaches was reported by 29 (66%). Tension-type headaches were more likely than migraine to remit (P<.04). Headache severity at diagnosis was predictive of headache outcome at 20 years. During the month before follow-up, nonprescription medications were used by 31 (70%) of those with ongoing headaches, and prescription medications were used by 6 (14%). However, 20 (45%) believed that nonpharmacological methods were most effective. Medication use increased during the 10 years since last follow-up. No patient used selective serotonin receptor agonists (triptans). CONCLUSIONS: Twenty years after diagnosis of pediatric headache, most patients continue to have headache, although the headache classification often changes across time. Most patients report moderate or severe headache and increasingly choose to care for their headaches pharmacologically. AD - Division of Pediatric Neurology, Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada. pbrna@hotmail.com AN - 16330740 AU - Brna, P. AU - Dooley, J. AU - Gordon, K. AU - Dewan, T. DA - Dec DO - 10.1001/archpedi.159.12.1157 DP - NLM ET - 2005/12/07 IS - 12 KW - Canada/epidemiology Child Disease Progression Female Follow-Up Studies Humans Male Migraine Disorders/*diagnosis/epidemiology Pain Measurement Prevalence Prognosis Retrospective Studies Severity of Illness Index Tension-Type Headache/*diagnosis/epidemiology Time Factors LA - eng N1 - Brna, Paula Dooley, Joseph Gordon, Kevin Dewan, Tammie Comparative Study Journal Article United States Arch Pediatr Adolesc Med. 2005 Dec;159(12):1157-60. doi: 10.1001/archpedi.159.12.1157. PY - 2005 SN - 1072-4710 (Print) 1072-4710 SP - 1157-60 ST - The prognosis of childhood headache: a 20-year follow-up T2 - Arch Pediatr Adolesc Med TI - The prognosis of childhood headache: a 20-year follow-up VL - 159 ID - 3607 ER - TY - JOUR AB - Sickle cell anaemia in children is characterised by recurrent crises that frequently involve intensive medical care which may impact on the health and well-being of their carers. The psychosocial impact of sickle cell disease on 67 carers of children with sickle cell disease attending the Paediatric Haematology/Oncology clinic of the University College Hospital, Ibadan, Nigeria, was determined between February and May 2007 using a structured questionnaire adapted from an instrument earlier validated for the study of carer burden in sickle cell disease and relevant to the Nigerian culture. Data analysis was performed using the Statistical Package for Social Sciences (SPSS) version 15.0. Demographic factors as well as frequency of hospitalisations and blood transfusions were each categorised into groups and the Mann-Whitney U-test was used to test for differences in stress scores between any two groups while the Kruskal-Wallis test was used to test for differences in more than two groups. Level of statistical significance was set at P < 0.05. Family finances were adversely affected in 39 (58.2%) families. Financial stress was frequently associated with a history of two or more hospitalisations in the previous year and more so in families with more than three children. Majority (80.6%) of the carers said they had minimal or no difficulty coping with their children. There was also a significant correlation between financial stress and difficulty in parental coping. Caring for the illnesses in the children often caused disruptions in family interactions; worst in the first year after diagnosis and improved over the years. Regular assessment of psychosocial areas of need is necessary to guide provision of necessary support. AN - WOS:000276861500008 AU - Brown, B. J. AU - Okereke, J. O. AU - Lagunju, A. AU - Orimadegun, A. E. AU - Ohaeri, J. U. AU - Akinyinka, O. O. DA - May DO - 10.1111/j.1365-2524.2009.00903.x IS - 3 N1 - Brown, B. J. Okereke, J. O. Lagunju, A. Orimadegun, A. E. Ohaeri, J. U. Akinyinka, O. O. Orimadegun, Adebola E/H-9330-2013 Orimadegun, Adebola E/0000-0001-5590-0039; Akinyinka, Olusegun/0000-0001-6752-8502 1365-2524 PY - 2010 SN - 0966-0410 SP - 289-295 ST - Burden of health-care of carers of children with sickle cell disease in Nigeria T2 - Health & Social Care in the Community TI - Burden of health-care of carers of children with sickle cell disease in Nigeria UR - ://WOS:000276861500008 VL - 18 ID - 2554 ER - TY - JOUR AB - Parents with chronic pain have a higher likelihood of having depression and anxiety and more often have children with these conditions. Depressive and anxious symptoms in children worsen pain-related disability and may be derived from exposure to their parents' symptoms. We assessed a model of intergenerational chronic pain-related disability that relies upon depressive and anxious symptoms of a mother and their child. Adolescents in grades 5 to 10 from 5 schools, and their mothers, completed standardized electronic questionnaires about pain. In maternal-offspring dyads (n = 1179), the mean offspring age was 12.7 years (SD = 1.7, range = 10-17) and 51% were girls. Logistic regression was used to investigate mother-offspring associations of chronic pain presence, and mediation models using multiple linear regression were used to investigate the proposed model. Adolescents of mothers with chronic pain had 1.67 (95% confidence interval [CI] = 1.29-2.16) times increased odds of chronic pain, with each year of exposure to maternal chronic pain associated with a 5% (odds ratio 95% CI = 1.01-1.10) increased likelihood of offspring chronic pain. Worse maternal pain-related disability was associated with worse offspring pain-related disability (beta = 0.20, 95% CI = 0.06-0.34). The mediation model indicated maternal and adolescent offspring symptoms of depression explained 36% of the relationship between maternal and offspring pain-related disability, with 11% explained by the intergenerational transmission of depression (serial mediation). We conclude that worse pain-related disability is associated between parent and child, and that depressive symptoms common to both mother and child play a key role in this relationship. AN - WOS:000656632900030 AU - Brown, D. AU - Rosenthal, N. AU - Konning, A. AU - Wager, J. DA - Feb DO - 10.1097/j.pain.0000000000002066 IS - 2 N1 - Brown, Donnamay Rosenthal, Nicola Koenning, Anna Wager, Julia 1872-6623 PY - 2021 SN - 0304-3959 SP - 653-662 ST - Intergenerational transmission of chronic pain-related disability: the explanatory effects of depressive symptoms T2 - Pain TI - Intergenerational transmission of chronic pain-related disability: the explanatory effects of depressive symptoms UR - ://WOS:000656632900030 VL - 162 ID - 1757 ER - TY - JOUR AB - BACKGROUND: Concussion literature and treatment guidelines are inconclusive regarding the role of sex in symptom reporting at baseline and post-concussion. Although empirical evidence is lacking, it is generally regarded that females have a more severe symptomatic presentation than males at all time-points on the concussion spectrum. OBJECTIVES: Our objective was to determine whether differences exist between males and females at baseline (pre-season/before concussion) or post-concussion for self-reported (1) prevalence of individual symptoms and (2) total symptom scores in high school and college athletes. DESIGN: Systematic review and meta-analysis of observational cohort studies; level of evidence, 1. METHODS: A computerized search of the PubMed, SPORTDiscus, CINAHL, and Scopus databases was performed. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) guidelines were followed. Criteria for inclusion were (1) self-report of symptoms at any time within the concussion spectrum, including baseline and after concussion, (2) study sample included high school and/or collegiate athletes aged 12-26 years, (3) concussions occurred during participation in sport, and (4) symptom reporting was separated by sex. The Quality Assessment Tool for Cohort Studies, Q-Coh, was utilized for quality assessment. RESULTS: Twenty-one studies met the criteria for inclusion: seventeen had good quality and four, acceptable quality. At baseline, females had significantly higher odds than males of reporting the individual symptoms of vision/hearing problems, headache/migraine, difficulty concentrating, energy/sleep disturbances, and emotional disturbances. Post-concussion, only one symptom demonstrated significant differences between males and females, with females demonstrating lower odds of reporting confusion than males. Statistically, at baseline and post-concussion, females had significantly higher total symptom scores on the Post-Concussion Scale (PCS) and the Sport Concussion Assessment Tool 2 (SCAT2), but when the standard mean difference was interpreted after back-transformation, these results were clinically insignificant. CONCLUSIONS: The symptomatic presentation of males and females, most notably the prevalence of specific symptoms, is very divergent. Females had higher total symptom scores at baseline and post-concussion, however, clinically this cannot be interpreted as a meaningful difference. It is possible that these differences can be explained by normal hormonal changes associated with the menstrual cycle. The implications of these findings are that symptomatic presentation during an individual female's menstrual cycle needs to be taken into consideration post-concussion when making return-to-play decisions, as returning to a completely asymptomatic level may not be a reasonable expectation. AD - Division of Health Sciences, Physical Therapy Program, Walsh University, 2020 E Maple Street, North Canton, OH, 44720, USA. AN - 25971368 AU - Brown, D. A. AU - Elsass, J. A. AU - Miller, A. J. AU - Reed, L. E. AU - Reneker, J. C. DA - Jul DO - 10.1007/s40279-015-0335-6 DP - NLM ET - 2015/05/15 IS - 7 KW - Affective Symptoms/etiology Athletic Injuries/*diagnosis Brain Concussion/*diagnosis Cognition Disorders/etiology Dizziness/etiology Fatigue/etiology Female Headache/etiology Hearing Disorders/etiology Humans Male Migraine Disorders/etiology Sex Factors Sleep Wake Disorders/etiology Vision Disorders/etiology LA - eng N1 - 1179-2035 Brown, Dana A Elsass, Julie A Miller, Ashley J Reed, Lauren E Reneker, Jennifer C Journal Article Meta-Analysis Review Systematic Review New Zealand Sports Med. 2015 Jul;45(7):1027-40. doi: 10.1007/s40279-015-0335-6. PY - 2015 SN - 0112-1642 SP - 1027-40 ST - Differences in Symptom Reporting Between Males and Females at Baseline and After a Sports-Related Concussion: A Systematic Review and Meta-Analysis T2 - Sports Med TI - Differences in Symptom Reporting Between Males and Females at Baseline and After a Sports-Related Concussion: A Systematic Review and Meta-Analysis VL - 45 ID - 3936 ER - TY - JOUR AB - In recent years, fibromyalgia has become an increasingly recognized chronic syndrome. Although it occurs more frequently in adults, it is also seen among school-age children and adolescents. In such cases, it is known as juvenile fibromyalgia syndrome (JFS). The widespread pain and other possible symptoms associated with JFS can have a negative impact on the occupational performance and developmental tasks of children and adolescents. As experts in the areas of occupational performance, daily functional skills, and child development, occupational therapists have a potential role to play in the assessment and management of children and adolescents with JFS. To date, however, no occupational therapy management approach for clients with JFS has been documented in the professional literature. In this paper, we outline the clinical features of JFS, pertinent assessment areas, and potential management strategies using a cognitive-behavioral approach. AD - Children's Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, Ontario, Canada K1H 8L1. AN - 11715801 AU - Brown, G. T. AU - Delisle, R. AU - Gagnon, N. AU - Sauvé, A. E. DP - NLM ET - 2001/11/22 IS - 1 KW - Adolescent Chronic Disease Cognitive Behavioral Therapy/*methods Female Fibromyalgia/complications/*rehabilitation Humans Pain/etiology *Pain Management Patient Care Planning Social Support LA - eng N1 - Brown, G T Delisle, R Gagnon, N Sauvé, A E Case Reports Journal Article Review England Phys Occup Ther Pediatr. 2001;21(1):19-36. PY - 2001 SN - 0194-2638 (Print) 0194-2638 SP - 19-36 ST - Juvenile fibromyalgia syndrome: proposed management using a cognitive-behavioral approach T2 - Phys Occup Ther Pediatr TI - Juvenile fibromyalgia syndrome: proposed management using a cognitive-behavioral approach VL - 21 ID - 3410 ER - TY - JOUR AB - Background: Chronic pain is a frequent burden in the general population. Child maltreatment and bullying are risk factors for the development of chronic pain. Aim of this cross-sectional study was to investigate the association of child maltreatment and bullying and pain experiences in a representative sample of the general population. Materials and methods: A total of N= 2,491 people from the general population of Germany participated in the study (M-age = 48.3 years [SD= 18.2], 53.2 % female). Child maltreatment was assessed with the Childhood Trauma Questionnaire (CTQ), pain was rated with the Polytrauma Outcome (POLO)-physical state domain, depression scores were assessed with the Patient Health Questionnaire, and anxiety scores via the General Anxiety Disorder Questionnaire. Regression analyses were calculated to investigate the effect of bullying and child maltreatment, as well as depression, anxiety, and gender on pain experiences. Results: A significant correlation between increasing pain levels and number of adverse childhood experiences was found. With regard to specific types of maltreatment, largest effect sizes were found for emotional abuse. Bullying was significantly, but overall rather moderately, related to pain suffering. In women, all forms of maltreatment were associated with pain, while in men only sexual and physical abuse revealed significant effects. Although depression and anxiety scores were significantly associated with the experience of current pain, they did not change the effect of child maltreatment on pain significantly. Conclusion: In this sample of the general population, adverse childhood experiences were significantly associated with pain and showed cumulative effects, over and above depressive and anxiety symptoms. AN - WOS:000452738400002 AU - Brown, R. C. AU - Plener, P. L. AU - Braehler, E. AU - Fegert, J. M. AU - Huber-Langs, M. DO - 10.2147/jpr.S169135 N1 - Brown, Rebecca C. Plener, Paul L. Braehler, Elmar Fegert, Joerg M. Huber-Langs, Markus Braehler, Elmar/C-6535-2009; Fegert, Jorg M./AAY-2959-2020 Braehler, Elmar/0000-0002-2648-2728; Plener, Paul/0000-0003-4333-1494 PY - 2018 SN - 1178-7090 SP - 3099-3108 ST - Associations of adverse childhood experiences and bullying on physical pain in the general population of Germany T2 - Journal of Pain Research TI - Associations of adverse childhood experiences and bullying on physical pain in the general population of Germany UR - ://WOS:000452738400002 VL - 11 ID - 2040 ER - TY - BOOK A2 - Finley, G. A. A2 - McGrath, P. J. A2 - Chambers, C. T. AB - This chapter reviews literature pertaining to the management of pain within the school setting. Etiological issues underlying obstacles to school attendance are reviewed, including issues pertaining to make-up work, concerns among many children pertaining to use of the bathroom at school, diet and eating habits at school, relationship with a teacher or peer, fear of pain episodes at school, learning problems, test or performance anxiety, separation anxiety, and familial reinforcement of sick behavior. Interventions to increase school attendance are reviewed; these also include a careful assessment of the child and the family system, the use of behavioral interventions, as well as other treatment approaches, including the use of relaxation therapy and problem-solving therapy. Finally, specific directions for future research efforts and training also are provided. AN - WOS:000237541600005 AU - Brown, R. T. DO - 10.1007/978-1-59745-125-3_5 N1 - Brown, Ronald T. 5th Biennial International Forum on Pediatric Pain - Bringing Pain Relief to Children Oct 14-17, 2004 Nova Scotia, CANADA Brown, Ronald/0000-0002-9656-4614 PY - 2006 SN - 1-58829-628-8 SP - 113-129 ST - Managing pediatric pain at school T2 - Bringing Pain Relief to Children: Treatment Approaches TI - Managing pediatric pain at school UR - ://WOS:000237541600005 ID - 2745 ER - TY - JOUR AB - Background and Aims: Functional bowel disorders (FBD), such as irritable bowel syndrome (IBS), are increasingly more common in children and affect up to 20% of children. The etiology is multifactorial with no clear organic cause. Symptoms are recurrent and are associated with a reduced quality of life, school absences, and psychological challenges. Treatment options are variable. FODMAPs are short-chained carbohydrates, poorly absorbed by the gastrointestinal tract due to their increased osmotic activity and excess gas production from the bacterial fermentation process. There is a paucity of data examining dietary interventions that restrict carbohydrates in children with IBS. The aim of this study was to examine the use of the low FODMAP diet (LFD) in children with an FBD. Methods: A retrospective clinical case note review of children with an FBD managed with an LFD was undertaken. Anthropometry and clinical data were collected by a pediatric gastroenterology dietitian. An IBS satisfaction survey was used to assess diet outcomes. Statistical analyses were completed using Excel. Results: Of the 29 children included in this study, complete resolution of gastrointestinal symptoms was observed for 11 of 12 (92%) of those with bloating, 13 of 15 (87%) of those with diarrhea, and 17 of 22 (77%) of those with abdominal pain. Twenty-three (79%) participants reported an improvement of symptoms. Fructans were the most common symptom-causing carbohydrate. Conclusion: The LFD is a useful dietary treatment strategy for children with FBD. This study adds to the small body of evidence supporting FODMAP dietary interventions in children with FBD. Further prospective studies are required. AN - WOS:000626747900009 AU - Brown, S. C. AU - Whelan, K. AU - Gearry, R. B. AU - Day, A. S. DA - Apr DO - 10.1002/jgh3.12231 IS - 2 N1 - Brown, Stephanie C. Whelan, Kevin Gearry, Richard B. Day, Andrew S. Gearry, Richard B/H-3959-2019 Gearry, Richard B/0000-0002-2298-5141; Whelan, Kevin/0000-0001-5414-2950 PY - 2020 SN - 2397-9070 SP - 153-159 ST - Low FODMAP diet in children and adolescents with functional bowel disorder: A clinical case note review T2 - Jgh Open TI - Low FODMAP diet in children and adolescents with functional bowel disorder: A clinical case note review UR - ://WOS:000626747900009 VL - 4 ID - 1834 ER - TY - JOUR AB - Introduction The treatment of chronic functional nausea or nausea due to functional dyspepsia in children is generally symptomatic. Moreover, these disorders pose a risk for worse psychosocial and health outcomes in children. Hypnotherapy (HT), by its ability to positively influence gastrointestinal and psychosocial functioning, may be an effective treatment for chronic nausea. Methods and analysis To test efficacy, this multicentre, parallel, randomised controlled, open label trial evaluates whether gut-directed HT is superior to standard medical treatment (SMT) for reducing nausea. The study will be conducted at eleven academic and non-academic hospitals across the Netherlands. A total of 100 children (8-18 years), fulfilling the Rome IV criteria for chronic idiopathic nausea or functional dyspepsia with prominent nausea, will be randomly allocated (1: 1) to receive HT or SMT. Children allocated to the HT group will receive six sessions of HT during 3 months, while children allocated to the SMT group will receive six sessions of SMT+supportive therapy during the same period. The primary outcome will be the difference in the proportion of children with at least 50% reduction of nausea, compared with baseline at 12 months' follow-up. Secondary outcomes include the changes in abdominal pain, dyspeptic symptoms, quality of life, anxiety, depression, school absences, parental absence of work, healthcare costs and adequate relief of symptoms, measured directly after treatment, 6 and 12 months' follow-up. If HT proves effective for reducing nausea, it may become a new treatment strategy to treat children with chronic functional nausea or functional dyspepsia with prominent nausea. Ethics and dissemination Results of the study will be publicly disclosed to the public, without any restrictions, in peer-reviewed journal and international conferences. The study is approved by the Medical Research Ethics Committees United (MEC-U) in the Netherlands. Trial registration number NTR5814. AN - WOS:000471157200081 AU - Browne, P. D. AU - den Hollander, B. AU - Speksnijder, E. M. AU - van Wering, H. M. AU - Ten, W. T. A. AU - George, E. K. AU - Groeneweg, M. AU - Bevers, N. AU - Wessels, M. M. S. AU - Van den Berg, M. M. AU - Goede, J. AU - Teklenburg-Roord, S. T. A. AU - Frankenhuis, C. AU - Benninga, M. A. AU - Vlieger, A. M. C7 - e024903 DA - Jun DO - 10.1136/bmjopen-2018-024903 IS - 4 N1 - Browne, Pamela D. den Hollander, Bibiche Speksnijder, Esther M. van Wering, Herbert M. Ten, Walther Tjon A. George, Elvira K. Groeneweg, Michael Bevers, Nanja Wessels, Margaretha M. S. Van den Berg, Maartje M. Goede, Joery Teklenburg-Roord, Sarah T. A. Frankenhuis, Carla Benninga, Marc A. Vlieger, Arine M. vlieger, arine/ABE-8079-2020 den Hollander, Bibiche/0000-0003-1544-2402 PY - 2019 SN - 2044-6055 ST - Gut-directed hypnotherapy versus standard medical treatment for nausea in children with functional nausea or functional dyspepsia: protocol of a multicentre randomised trial T2 - Bmj Open TI - Gut-directed hypnotherapy versus standard medical treatment for nausea in children with functional nausea or functional dyspepsia: protocol of a multicentre randomised trial UR - ://WOS:000471157200081 VL - 9 ID - 1913 ER - TY - JOUR AB - OBJECTIVE: To describe the development of a clinically and financially successful interdisciplinary pediatric pain rehabilitation program at a large tertiary academic medical center and present demographic and clinical information on the first 1000 patients. PATIENTS AND METHODS: All patients who were consecutively admitted to this program between October 1, 2008, and March 31, 2015 were included in this review. The patients ranged in age from 9 to 24 years. The program is a 3-week, hospital-based outpatient treatment program that requires substantial parental involvement. At admission and discharge, patients completed the Center for Epidemiologic Studies of Depression Scale for Children, the Functional Disability Inventory, and the Pain Catastrophizing Scale for Children. Opioid use was also assessed. RESULTS: At admission, patients reported substantial pain-associated disability and depressive symptoms; they had elevated pain catastrophizing scores, and 16% were taking opioids. Primary sites/types of pain included head, abdomen, and generalized. Functional disability scores decreased significantly, from 27 to 9 after the program (P<.001). Depression scale scores improved from 27 to 14 (P<.001). Pain catastrophizing scores decreased significantly, from 26 to 14 (P<.001), at discharge from the program. All but 4 patients successfully tapered off of all opioid use by the conclusion of the program. CONCLUSION: Participation in a multidisciplinary pediatric pain rehabilitation program can be successful, with significant decreases in disability, depression symptoms, and pain catastrophizing, as well as discontinuation of opioid use. AD - Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN. Division of Pediatric Anesthesia, Department of Anesthesia, Mayo Clinic, Rochester, MN. Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN. AN - 30225410 AU - Bruce, B. K. AU - Weiss, K. E. AU - Ale, C. M. AU - Harrison, T. E. AU - Fischer, P. R. C2 - PMC6135035 DA - Sep DO - 10.1016/j.mayocpiqo.2017.05.006 DP - NLM ET - 2017/07/26 IS - 2 KW - CBT, cognitive behavioral therapy POTS, postural orthostatic tachycardia syndrome LA - eng N1 - 2542-4548 Bruce, Barbara K Weiss, Karen E Ale, Chelsea M Harrison, Tracy E Fischer, Philip R Journal Article Mayo Clin Proc Innov Qual Outcomes. 2017 Jul 26;1(2):141-149. doi: 10.1016/j.mayocpiqo.2017.05.006. eCollection 2017 Sep. PY - 2017 SN - 2542-4548 SP - 141-149 ST - Development of an Interdisciplinary Pediatric Pain Rehabilitation Program: The First 1000 Consecutive Patients T2 - Mayo Clin Proc Innov Qual Outcomes TI - Development of an Interdisciplinary Pediatric Pain Rehabilitation Program: The First 1000 Consecutive Patients VL - 1 ID - 4072 ER - TY - JOUR AB - In this nationwide study, 1975 students from grades 3, 6, and 9 (ages 9, 12, and 15 at the onset of the year), were recruited from randomly selected schools, which represented different geographical areas throughout Sweden. The main aim of the study was to assess the prevalence of self-reported pain (headache, abdominal, and musculoskeletal pain) and perceived health (problems sleeping and/or if they often felt tired, lonely and sad). A second aim was to study the co-occurrence among different pain and health variables. The students, (n = 1908 distributed by grade 3: 255 girls and 305 boys, grade 6: 347 girls and 352 boys, grade 9: 329 girls and 320 boys) answered retrospectively (three months) a specially designed questionnaire. Fifty percent (50%) of the students reported that they had experienced pain, either as headache, abdominal pain or musculoskeletal pain, within the recall period. Gender differences were especially noticeable for headaches, where twice as many girls (17%, n = 159) than boys (8%, n = 80) reported that they suffered such pain at least once a week or more often. Co-occurrence among the variables was moderate (0.3-0.5). For the total of the seven variables, the perception of pain and health complaints decreased with age for boys from grades 3 to 9, while multiple complaints increased for girls. AU - Brun Sundblad, Gunilla M. AU - Saartok, Tönu AU - Engström, Lars-Magnus T. DA - 2007/02// DO - 10.1016/j.ejpain.2006.02.006 DP - PubMed IS - 2 J2 - Eur J Pain KW - Abdominal Pain Adolescent Age Distribution Attitude to Health Child Depression Fatigue Female Headache Humans Loneliness Male Musculoskeletal Diseases Prevalence Retrospective Studies Sex Characteristics Sex Distribution Sleep Wake Disorders Surveys and Questionnaires Sweden LA - eng PY - 2007 SN - 1090-3801 SP - 171-180 ST - Prevalence and co-occurrence of self-rated pain and perceived health in school-children T2 - European Journal of Pain (London, England) TI - Prevalence and co-occurrence of self-rated pain and perceived health in school-children: Age and gender differences UR - http://www.ncbi.nlm.nih.gov/pubmed/16542860 VL - 11 ID - 116 ER - TY - JOUR AB - Background: Headache and sleep are related in different ways and alterations of chronobiological mechanisms are involved in headache. We investigated the relationships between headache and sleep quality in a large non-clinical population of children and adolescents and evaluated the relationship between headache and circadian typologies. Methods: A total of 1073 children and adolescents (50.9% males; mean age = 10.56; range = 8-15 years) were recruited from four schools in Rome. They filled out the questionnaires individually in classrooms, after brief group instruction about answer formats. The questionnaires included (a) a self-report headache questionnaire to collect information on different aspects of headache attacks based on the International Classification of Headache Disorders-2nd edition (ICHD-2); (b) the School Sleep Habits Survey that incorporated questions about sleep habits, the Sleep-Wake Problems Behaviour Scale (SWPBS), the Sleepiness Scale (SLS) and the Morningness/Eveningness Questionnaire (MEQ). Results: According to ICHD-2 criteria, we classified 70 (6.5%) children as Migraine Group (MG), 135 (12.7%) as Non-Migraine Headache Group (NMG), and the remaining 868 (80.8%) were classified as Headache-Free Group (HFG). No clear differences have been found between MG and NMG regarding the frequency of the attacks, although MG showed a significantly increased frequency of long-lasting attacks. The modality of onset of pain and the location of pain was similar in both groups. The most frequent triggering factor for headache in MG and NMG was "a bad sleep" (32.2%) followed by emotional distress (27.8%). No differences have been found between MG, NMG and HFG in sleep schedule or sleep duration. MG and NMG showed significantly higher scores on the SWPBS vs. HFG, while MG presented higher scores on the SLS compared to NMG and HFG. MG presented lower MEQ scores, indicating a more pronounced eveningness. Conclusions: The relationships between headache and sleep problems are evident even in a non-clinical population of children and adolescents, with MG showing poorer sleep quality, sleepiness and a tendency toward eveningness. (C) 2007 Elsevier B.V. All rights reserved. AN - WOS:000257913100013 AU - Bruni, O. AU - Russo, P. M. AU - Ferri, R. AU - Novelli, L. AU - Galli, F. AU - Guidetti, V. DA - Jul DO - 10.1016/j.sleep.2007.08.010 IS - 5 N1 - Bruni, O. Russo, P. M. Ferri, R. Novelli, L. Galli, F. Guidetti, V. Ferri, Raffaele/B-5439-2013; Galli, Federica/AAL-5452-2020; Russo, Paolo/AAO-5351-2021; Bruni, Oliviero/A-4029-2008 Ferri, Raffaele/0000-0001-6937-3065; Bruni, Oliviero/0000-0003-2207-1398; Guidetti, Vincenzo/0000-0003-1643-8392; RUSSO, PAOLO MARIA/0000-0002-0575-5360; Galli, Federica/0000-0003-0491-0338 1878-5506 PY - 2008 SN - 1389-9457 SP - 542-548 ST - Relationships between headache and sleep in a non-clinical population of children and adolescents T2 - Sleep Medicine TI - Relationships between headache and sleep in a non-clinical population of children and adolescents UR - ://WOS:000257913100013 VL - 9 ID - 2644 ER - TY - JOUR AB - Recurrent abdominal pain (RAP) is one of the most common health complaints in both children and adults. Although RAP is considered a functional disorder rather than an organic disease, affected children and their families can still experience anxiety and concerns that can interfere with school, sports, and regular daily activities and lead to frequent attendances at pediatric emergency departments or pediatric gastroenterology clinics. Our review shows experts do not agree on a universally proven management that will work on every child presenting with functional abdominal pain (FAP). Treatment strategies include both non-pharmacological and pharmacological options. Non-pharmacological treatments are usually very well accepted by both children and their parents and are free from medication side effects. Nevertheless, they may be as effective as the pharmacological interventions; therefore, according to many experts and based on the majority of current evidence, a non-pharmacological approach should be the first intervention attempt in children with RAP. In particular, the importance of the bio-psychosocial approach is highlighted, as a majority of children will improve with counselling and reassurance that no serious organic pathologies are suspected, especially when the physician establishes a trustful relationship with both the child and their family. Placebo and pharmacological interventions could be attempted when the bio-psychosocial approach is not applicable or not efficacious. In some difficult cases, finding an effective treatment for FAP can be a challenge, and a number of strategies may need to be tried before symptoms are controlled. In these cases, a multidisciplinary team, comprising a pediatric gastroenterologist, dietician, psychologist, and psychotherapist, is likely to be successful. AN - WOS:000432367500004 AU - Brusaferro, A. AU - Farinelli, E. AU - Zenzeri, L. AU - Cozzali, R. AU - Esposito, S. DA - Jun DO - 10.1007/s40272-018-0287-z IS - 3 N1 - Brusaferro, Andrea Farinelli, Edoardo Zenzeri, Letizia Cozzali, Rita Esposito, Susanna zenzeri, letizia/AAA-8190-2019; Farinelli, Edoardo/V-3854-2019; Esposito, Susanna/K-3475-2016 zenzeri, letizia/0000-0001-5220-680X; Esposito, Susanna/0000-0003-4103-2837; Farinelli, Edoardo/0000-0002-6075-0554 1179-2019 PY - 2018 SN - 1174-5878 SP - 235-247 ST - The Management of Paediatric Functional Abdominal Pain Disorders: Latest Evidence T2 - Pediatric Drugs TI - The Management of Paediatric Functional Abdominal Pain Disorders: Latest Evidence UR - ://WOS:000432367500004 VL - 20 ID - 2014 ER - TY - JOUR AB - Pain and fear widely contribute to negative experiences for students during school-based immunizations. In this preliminary research, we used a pre-existing network of 50 schools across Canada that participated in a biannual national immunization poster competition for grade 6 students organized by Immunize Canada to survey principals, teachers and students about their experiences with immunization pain and fear, how they want to learn about managing pain and fear and opportunities to include this information in the process of immunization. Responses revealed that both pain and fear are relevant to the immunization experience and that education and interventions are welcome by students and school staff. This may lead to improved attitudes about immunization, as well as future compliance with recommended immunizations. AN - WOS:000401441000013 AU - Bucci, L. M. AU - MacDonald, N. E. AU - Sondagar, C. AU - Taddio, A. DA - Mar DO - 10.1093/pch/pxx004 IS - 1 N1 - Bucci, Lucie Marisa MacDonald, Noni E. Sondagar, Chandni Taddio, Anna PY - 2017 SN - 1205-7088 SP - 41-42 ST - Taking the sting out of school-based immunizations T2 - Paediatrics & Child Health TI - Taking the sting out of school-based immunizations UR - ://WOS:000401441000013 VL - 22 ID - 2105 ER - TY - JOUR AB - Pediatric headache is an increasingly reported phenomenon. Cervicogenic headache (CGH) is a subgroup of headache, but there is limited information about cervical spine physical examination signs in children with CGH. Therefore, a cross-sectional study was designed to investigate cervical spine physical examination signs including active range of motion (ROM), posture determined by the craniovertebral angle (CVA), and upper cervical ROM determined by the flexion-rotation test (FRT) in children aged between 6 and 12 years. An additional purpose was to determine the degree of pain provoked by the FRT. Thirty children (mean age 120.70 months [SD 15.14]) with features of CGH and 34 (mean age 125.38 months [13.14]) age-matched asymptomatic controls participated in the study. When compared to asymptomatic controls, symptomatic children had a significantly smaller CVA (p < 0.001), significantly less active ROM in all cardinal planes (p < 0.001), and significantly less ROM during the FRT (p < 0.001), especially towards the dominant headache side (p < 0.001). In addition, symptomatic subjects reported more pain during the FRT (p < 0.001) and there was a significant negative correlation (r = -0.758, p < 0.001) between the range recorded during the FRT towards the dominant headache side and FRT pain intensity score. This study found evidence of impaired function of the upper cervical spine in children with CGH and provides evidence of the clinical utility of the FRT when examining children with CGH. AN - WOS:000324816900010 AU - Budelmann, K. AU - von Piekartz, H. AU - Hall, T. DA - Oct DO - 10.1007/s00431-013-2046-z IS - 10 N1 - Budelmann, Kim von Piekartz, Harry Hall, Toby von Piekartz, Harry/I-4163-2019 von Piekartz, Harry/0000-0002-4509-929X; Hall, Toby/0000-0003-4461-7259 1432-1076 PY - 2013 SN - 0340-6199 SP - 1349-1356 ST - Is there a difference in head posture and cervical spine movement in children with and without pediatric headache? T2 - European Journal of Pediatrics TI - Is there a difference in head posture and cervical spine movement in children with and without pediatric headache? UR - ://WOS:000324816900010 VL - 172 ID - 2345 ER - TY - JOUR AB - Background: Headache is a public health problem affecting life quality negatively. The present cross-sectional, selective (2nd-5th grades) study was conducted to determine the prevalence of recurrent headache in schoolchildren in Mersin, a city of Turkey. Methods: A stratified sample of 5777 students was selected to be representative of the city's schoolchildren population. After the data quality control process, the study sample was reduced to 5562 schoolchildren. Result: The prevalence of recurrent headache was 49.2% (2739/5562). Among the studied population 24.7% had tension-type headache and 10.4% had migraine. Girls had significantly more frequent headache than boys. Binary logistic regression analysis found that increasing age, female gender, low socioeconomic status of family, low education level of mother, and positive family history of headache (father, mother, siblings, second degree relatives) had a statistically significant effect on the presence of headache in children. Additionally, having travel sickness had a statistically significant effect on schoolchildren headache (P = 0.000). Conclusion: Headache is a common health problem among schoolchildren in Mersin, which merits increased attention and detailed multicentre epidemiological and clinical studies. AN - WOS:000229190200016 AU - Bugdayci, R. AU - Ozge, A. AU - Sasmaz, T. AU - Kurt, A. O. AU - Kaleagasi, H. AU - Karakelle, A. AU - Tezcan, H. AU - Siva, A. DA - Jun DO - 10.1111/j.1442-200x.2005.02051.x IS - 3 N1 - Bugdayci, R Ozge, A Sasmaz, T Kurt, AO Kaleagasi, H Karakelle, A Tezcan, H Siva, A Sasmaz, Tayyar/I-6090-2015; Siva, Aksel/A-5132-2016; Bugdayci, Resul/G-7530-2018 Sasmaz, Tayyar/0000-0002-3923-570X; Siva, Aksel/0000-0002-8340-6641; 1442-200x PY - 2005 SN - 1328-8067 SP - 316-322 ST - Prevalence and factors affecting headache in Turkish schoolchildren T2 - Pediatrics International TI - Prevalence and factors affecting headache in Turkish schoolchildren UR - ://WOS:000229190200016 VL - 47 ID - 2762 ER - TY - JOUR AB - The present preliminary study was aimed at investigating the electrocortical correlates of attentional allocation toward emotional stimuli in children and adolescents with migraine by means of the event-related potentials. The electroencephalogram was continuously recorded in 7 migrainous children and 8 healthy controls while they were looking at a series of pleasant, neutral, and unpleasant pictures. The mean amplitude of the Negative Central component of the event-related potentials was computed as an index of the allocation of attentional resources to the presented stimuli. Relative to controls, children with migraine displayed reduced fronto-central negativity and larger posterior positivity in response to emotional pictures. This effect was already evident, overall, in a time window preceding the Negative Central component. The smaller cortical negativity in response to emotional stimuli suggests reduced attentional engagement toward emotionally relevant stimuli, or might be interpreted in terms of advanced brain maturation in migraine children. AN - WOS:000297312100006 AU - Buodo, G. AU - Sarlo, M. AU - Battistella, P. A. AU - Naccarella, C. AU - Palomba, D. DA - Dec DO - 10.1177/0883073811408905 IS - 12 N1 - Buodo, Giulia Sarlo, Michela Battistella, Pier Antonio Naccarella, Cristiana Palomba, Daniela Sarlo, Michela/AAP-4606-2020; Buodo, Giulia/D-1229-2014; Sarlo, Michela/I-7414-2012 Sarlo, Michela/0000-0001-6652-7604; Buodo, Giulia/0000-0002-8701-248X; Sarlo, Michela/0000-0001-6652-7604; Palomba, Daniela/0000-0003-1656-4209 1708-8283 PY - 2011 SN - 0883-0738 SP - 1508-1515 ST - Event-Related Potentials to Emotional Stimuli in Migrainous Children T2 - Journal of Child Neurology TI - Event-Related Potentials to Emotional Stimuli in Migrainous Children UR - ://WOS:000297312100006 VL - 26 ID - 2467 ER - TY - JOUR AB - OBJECTIVE: Guidelines recommend that clinicians make decisions about opioid tapering for patients with chronic pain using a benefit-to-harm framework and engaging patients. Studies have not examined clinician documentation about opioid tapering using this framework. DESIGN AND SETTING: Thematic and content analysis of clinician documentation about opioid tapering in patients' medical records in a large academic health system. METHODS: Medical records were reviewed for patients aged 18 or older, without cancer, who were prescribed stable doses of long-term opioid therapy between 10/2015 and 10/2016 then experienced an opioid taper (dose reduction ≥30%) between 10/2016 and 10/2017. Inductive thematic analysis of clinician documentation within six months of taper initiation was conducted to understand rationale for taper, and deductive content analysis was conducted to determine the frequencies of a priori elements of a benefit-to-harm framework. RESULTS: Thematic analysis of 39 patients' records revealed 1) documented rationale for tapering prominently cited potential harms of continuing opioids, rather than observed harms or lack of benefits; 2) patient engagement was variable and disagreement with tapering was prominent. Content analysis found no patients' records with explicit mention of benefit-to-harm assessments. Benefits of continuing opioids were mentioned in 56% of patients' records, observed harms were mentioned in 28%, and potential harms were mentioned in 90%. CONCLUSIONS: In this study, documentation of opioid tapering focused on potential harms of continuing opioids, indicated variable patient engagement, and lacked a complete benefit-to-harm framework. Future initiatives should develop standardized ways of incorporating a benefit-to-harm framework and patient engagement into clinician decisions and documentation about opioid tapering. AD - Department of Medicine, Albert Einstein College of Medicine and Montefiore Health System, Bronx, New York. Department of Physical Medicine and Rehabilitation, New York-Presbyterian Columbia/Cornell, New York, New York. Department of Emergency Medicine, SUNY Downstate Medical Center, Brooklyn, New York. Center for Research on Healthcare, Divisions of General Internal Medicine and Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA. AN - 32142143 AU - Buonora, M. AU - Perez, H. R. AU - Stumph, J. AU - Allen, R. AU - Nahvi, S. AU - Cunningham, C. O. AU - Merlin, J. S. AU - Starrels, J. L. C2 - PMC7593794 DA - Oct 1 DO - 10.1093/pm/pnz361 DP - NLM ET - 2020/03/07 IS - 10 KW - Adolescent *Analgesics, Opioid *Chronic Pain/drug therapy Documentation Humans Medical Records Patient Participation *Chronic Pain *Clinician Documentation *Opioid Taper *Pain Management *Primary Care LA - eng N1 - 1526-4637 Buonora, Michele Perez, Hector R Stumph, Jordan Allen, Robert Nahvi, Shadi Cunningham, Chinazo O Merlin, Jessica S Starrels, Joanna L K23 DA044327/DA/NIDA NIH HHS/United States K24 DA036955/DA/NIDA NIH HHS/United States UL1 TR001073/TR/NCATS NIH HHS/United States UL1 TR002556/TR/NCATS NIH HHS/United States K24 DA046309/DA/NIDA NIH HHS/United States R01 DA039046/DA/NIDA NIH HHS/United States Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Pain Med. 2020 Oct 1;21(10):2574-2582. doi: 10.1093/pm/pnz361. PY - 2020 SN - 1526-2375 (Print) 1526-2375 SP - 2574-2582 ST - Medical Record Documentation About Opioid Tapering: Examining Benefit-to-Harm Framework and Patient Engagement T2 - Pain Med TI - Medical Record Documentation About Opioid Tapering: Examining Benefit-to-Harm Framework and Patient Engagement VL - 21 ID - 3048 ER - TY - JOUR AB - OBJECTIVE: To study the differences in levels of alexithymia, depression, and anxiety between a sample of adolescents diagnosed with ICD-10 persistent somatoform pain disorder (defined by the DSM-IV as a pain disorder associated with psychological factors) and healthy adolescent control subjects. METHOD: Using the Toronto Alexithymia Scale and the Hospital Anxiety and Depression Scale, we investigated the point prevalence of alexithymia, anxiety, and depression among adolescents aged 12 to 17 years, with somatoform disorder, who were hospitalized in Kaunas Medical University Hospital, Lithuania (n =120), and a healthy control group (n = 60) of adolescents aged 12 to 17 years, who were randomly selected from 6 schools in Kaunas, Lithuania. RESULTS: The rate of alexithymia in adolescents with somatoform disorder was 59%, which was significantly higher than that in healthy control subjects (1%, P < 0.001). Similarly, the rate of anxiety was significantly higher in the patient group (62%), compared with control subjects (15%, P < 0.001). The rate of depression was low in both groups and did not differ significantly between groups. CONCLUSIONS: Adolescents with somatoform disorder have higher levels of alexithymia and anxiety than healthy adolescent control subjects, but adolescents with somatoform disorder and adolescent control subjects do not have significantly different levels of depression. AD - Department of Psychiatry, Kaunas Medical University Hospital, Lithuania. AN - 16838829 AU - Burba, B. AU - Oswald, R. AU - Grigaliunien, V. AU - Neverauskiene, S. AU - Jankuviene, O. AU - Chue, P. DA - Jun DO - 10.1177/070674370605100709 DP - NLM ET - 2006/07/15 IS - 7 KW - Adolescent Affective Symptoms/*diagnosis/epidemiology/psychology Anxiety Disorders/diagnosis/epidemiology/psychology Child Chronic Disease Comorbidity Cross-Sectional Studies Depressive Disorder/diagnosis/epidemiology/psychology Female Humans Lithuania Male Pain/epidemiology/*psychology Personality Inventory/statistics & numerical data Psychometrics/statistics & numerical data Reference Values Somatoform Disorders/*diagnosis/epidemiology/psychology LA - eng N1 - Burba, Benjaminas Oswald, Ronald Grigaliunien, Viktorija Neverauskiene, Simona Jankuviene, Odeta Chue, Pierre Journal Article United States Can J Psychiatry. 2006 Jun;51(7):468-71. doi: 10.1177/070674370605100709. PY - 2006 SN - 0706-7437 (Print) 0706-7437 SP - 468-71 ST - A controlled study of alexithymia in adolescent patients with persistent somatoform pain disorder T2 - Can J Psychiatry TI - A controlled study of alexithymia in adolescent patients with persistent somatoform pain disorder VL - 51 ID - 3567 ER - TY - JOUR AB - Neonatal injury is associated with persistent changes in sensory function and altered nociceptive thresholds that give rise to aberrant pain sensitivity in later life. Although these changes are well documented in adult rodents, little is known about the consequences of neonatal injury during adolescence. Because adolescence is a critical developmental period during which persistent pain conditions can arise, we examined the effect of neonatal injury on nociception, social behavior, and response to morphine in adolescent Sprague Dawley rats. Male and female rats exposed to plantar incision injury at postnatal day 3 displayed mechanical hypersensitivity that resolved by 24 hours after incision. When these animals reached adolescence (postnatal day 28-40), neonatally -injured male rats showed ipsilaterally restricted mechanical, heat, and cold hypersensitivity, as well as social behavioral deficits. In contrast, these effects were not seen in female rats. Neonatal injury did not alter acute morphine antinociception or the development of analgesic tolerance in either sex. Morphine-induced conditioned place preference, behavioral sensitization, and physical withdrawal were also not affected by neonatal incision. Thus, early-life injury results in sex-dependent pain related hypersensitivity and social behavior deficits during adolescence, without altering the response to opioids. Perspective: Neonatal surgery has greater effects on adolescent male than female rats, resulting in pain-related hypersensitivity and social behavioral deficits. Neonatal surgery does not alter the anti-nociceptive effects of morphine or abuse liability. (C) 2017 by the American Pain Society AN - WOS:000414381400010 AU - Burke, N. N. AU - Trang, T. DA - Nov DO - 10.1016/j.jpain.2017.07.003 IS - 11 N1 - Burke, Nikita N. Trang, Tuan Burke, Nikita/AAX-2647-2020 Burke, Nikita/0000-0001-8688-1512 PY - 2017 SN - 1526-5900 SP - 1384-1396 ST - Neonatal Injury Results in Sex-Dependent Nociceptive Hypersensitivity and Social Behavioral Deficits During Adolescence, Without Altering Morphine Response T2 - Journal of Pain TI - Neonatal Injury Results in Sex-Dependent Nociceptive Hypersensitivity and Social Behavioral Deficits During Adolescence, Without Altering Morphine Response UR - ://WOS:000414381400010 VL - 18 ID - 2065 ER - TY - JOUR AB - OBJECTIVE: To examine the efficacy and safety of conservative management of mild otitis media ("the acute red ear") in children. DESIGN: Double blind placebo controlled trial. SETTING: 17 group general practices (48 general practitioners) in Southampton, Bristol, and Portsmouth. PATIENTS: 232 children aged 3-10 years with acute earache and at least one abnormal eardrum (114 allocated to receive antibiotic, 118 placebo). INTERVENTIONS: Amoxycillin 125 mg three times a day for seven days or matching placebo; 100 ml paracetamol 120 mg/5 ml. MAIN OUTCOME MEASURES: Diary records of pain and crying, use of analgesic, eardrum signs, failure of treatment, tympanometry at one and three months, recurrence rate, and ear, nose, and throat referral rate over one year. RESULTS: Treatment failure was eight times more likely in the placebo than the antibiotic group (14.4% v 1.7%, odds ratio 8.21, 95% confidence interval 1.94 to 34.7). Children in the placebo group showed a significantly higher incidence of fever on the day after entry (20% v 8%, p less than 0.05), mean analgesic consumption (0.36 ml/h v 0.21 ml/h, difference 0.14, 95% confidence interval 0.07 to 0.23; p = 0.0022), mean duration of crying (1.44 days v 0.50 days, 0.94; 0.50 to 1.38; p less than 0.001), and mean absence from school (1.96 days v 0.52 days, 1.45; 0.46 to 2.42; p = 0.0132). Differences in recorded pain were not significant. The prevalence of middle ear effusion at one or three months, as defined by tympanometry, was not significantly different, nor was there any difference in recurrence rate or in ear, nose, and throat referral rate in the follow up year. No characteristics could be identified which predicted an adverse outcome. CONCLUSIONS: Use of antibiotic improves short term outcome substantially and therefore continues to be an appropriate management policy. AD - Primary Medical Care Group, University of Southampton, Aldermoor Health Centre. AN - 1912887 AU - Burke, P. AU - Bain, J. AU - Robinson, D. AU - Dunleavey, J. C2 - PMC1670875 DA - Sep 7 DO - 10.1136/bmj.303.6802.558 DP - NLM ET - 1991/09/07 IS - 6802 KW - Acetaminophen/*therapeutic use Acoustic Impedance Tests Acute Disease Amoxicillin/*therapeutic use Child Child, Preschool Crying Double-Blind Method Earache/drug therapy/etiology Female Humans Male Otitis Media/*drug therapy Prognosis Recurrence Referral and Consultation Time Factors LA - eng N1 - 1468-5833 Burke, P Bain, J Robinson, D Dunleavey, J Clinical Trial Comparative Study Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't BMJ. 1991 Sep 7;303(6802):558-62. doi: 10.1136/bmj.303.6802.558. PY - 1991 SN - 0959-8138 (Print) 0959-8138 SP - 558-62 ST - Acute red ear in children: controlled trial of non-antibiotic treatment in general practice T2 - Bmj TI - Acute red ear in children: controlled trial of non-antibiotic treatment in general practice VL - 303 ID - 3592 ER - TY - JOUR AB - This paper introduces an empirically derived psychosocial assessment form that may facilitate the incorporation of the growing body of research on sickle cell into the psychosocial assessment process. The psychosocial assessment form was guided by two theoretical models that explain the variability in adjustment among children and adolescents with sickle cell-the Disability-Stress-Coping Model (Wallender, Varni, Babani, Banis, & Wilcox, 1989) and the Transactional Stress and Coping Model (Thompson, Gustafson, George Spock, 1994). The Psychosocial Assessment Form consists of two sections. The first section includes primary indicators of adjustment such as internalizing disorders, externalizing disorders, school performance, and difficulties in social relationships. The second section lists secondary indicators of adjustment including intrapersonal. factors, stress processing factors, and social ecological factors. The literature that guided this form is also reviewed. (C) 2002 by The Haworth Press, Inc. All rights reserved. AN - WOS:000179742000003 AU - Burlew, A. K. DO - 10.1300/J010v36n01_03 IS - 1 N1 - Burlew, AK 1541-034x PY - 2002 SN - 0098-1389 SP - 29-44 ST - Empirically derived guidelines for assessing the psychosocial needs of children and adolescents with sickle cell T2 - Social Work in Health Care TI - Empirically derived guidelines for assessing the psychosocial needs of children and adolescents with sickle cell UR - ://WOS:000179742000003 VL - 36 ID - 2842 ER - TY - JOUR AB - Objective: This guideline reviews the investigation and treatment of primary dysmenorrhea. Intended Users: Health care providers. Target Population: Women and adolescents experiencing menstrual pain for which no underlying cause has been identified. Evidence: Published clinical trials, population studies, and review articles cited in PubMed or the Cochrane database from January 2005 to March 2016. Validation Methods: Seven clinical questions were generated by the authors and reviewed by the SOGC Clinical Practice-Gynaecology Committee. The available literature was searched. Guideline No. 169 was reviewed and rewritten in order to incorporate current evidence. Recommendations addressing the identified clinical questions were formulated and evaluated using the ranking of the Canadian Task Force on Preventive Health Care. [GRAPHICS] . Benefits, Harms, and Costs: Primary dysmenorrhea is common and frequently undertreated. Effective therapy is widely available at minimal cost. Treatment has the potential to improve quality of life and to decrease time lost from school or work. Guideline Update: This guideline is a revision and update of No. 169, December 2005. Sponsors: SOGC. Summary Statements 1. Dysmenorrhea is highly prevalent and commonly undertreated (III). 2. Non-steroidal anti-inflammatory drugs are more effective than placebo but have more gastrointestinal side effects. All currently available non-steroidal anti-inflammatory drugs are of comparable efficacy and safety (I). 3. Suppression of ovulation is associated with decreased menstrual pain (II-1). 4. Amenorrhea induced by any means is beneficial for the treatment of dysmenorrhea (II-2). 5. Hysterectomy is effective treatment (II-2). 6. There is some evidence to support laparoscopic nerve ablation in selected cases (II-1). 7. Endometrial ablation is likely to reduce symptoms of dysmenorrhea when it occurs in the presence of menorrhagia (I). Recommendations 1. Both primary and secondary dysmenorrhea are likely to respond to the same medical therapy. Therefore, initiation of treatment should not depend on establishing a precise diagnosis (II-1A). 2. Health care providers should include specific questions regarding menstrual pain when obtaining a woman's medical history (III-B). 3. A pelvic examination is not necessary prior to initiating therapy (III-D). 4. A pelvic examination is indicated in patients not responding to conventional therapy and when organic pathology is suspected (III-B). 5. Non-steroidal anti-inflammatory drugs, administered with regular dosing regimens, should be considered first-line treatment for most women (I-A). 6. Hormonal therapies should be offered to women and girlswho are not currently planning pregnancy unless contraindications exist (I-A). 7. Continuous or extended use combined hormonal contraceptives are recommended (I-A). 8. Regular exercise is likely to improve symptoms of dysmenorrhea and should be recommended (II-1A). 9. Local heat in the form of heated pads or patches should be recommended as a complementary treatment for dysmenorrhea (I-A). 10. High-frequency transcutaneous electrical nerve stimulation should be considered as a complementary treatment or in women unable or unwilling to use conventional therapy (II-1B). 11. Acupoint stimulation should be considered for women wishing to use complementary or alternative therapies (II-1B). 12. Ginger is recommended for women wishing to use complementary or alternative therapies (I-A). 13. Preoperative investigations should include a detailed history and physical examination, ultrasound, and possibly magnetic resonance imaging to discover secondary causes for dysmenorrhea and to direct appropriate therapy (III-A). 14. Surgical intervention should only be considered if a concerted trial of medical therapy has not been successful (III-A). AN - WOS:000443572100016 AU - Burnett, M. AU - Lemyre, M. DA - Jul DO - 10.1016/j.jogc.2016.12.023 IS - 7 N1 - Burnett, Margaret Lemyre, Madeleine PY - 2017 SN - 1701-2163 SP - 585-595 ST - No. 345-Primary Dysmenorrhea Consensus Guideline T2 - Journal of Obstetrics and Gynaecology Canada TI - No. 345-Primary Dysmenorrhea Consensus Guideline UR - ://WOS:000443572100016 VL - 39 ID - 2090 ER - TY - JOUR AB - Summary of the concepts of prevention in low back pain (LBP): The general nature and course of commonly experienced LBP means that there is limited scope for preventing its incidence (first-time onset). Prevention, in the context of this guideline, is focused primarily on reduction of the impact and consequences of LBP. Primary causative mechanisms remain largely undetermined: risk factor modification will not necessarily achieve prevention. There is considerable scope, in principle, for prevention of the consequences of LBP - e.g. episodes (recurrence), care seeking, disability, and workloss. Different interventions and outcomes will be appropriate for different target populations (general population, workers, and children) yet inevitably there is overlap. Interventions that are essentially treatments in the clinical environment, focused on management of current symptoms, are not considered as 'prevention' for the purposes of this guideline: they are covered in the accompanying clinical guidelines Overarching comments: Overall, there is limited robust evidence for numerous aspects of prevention in LBP. Nevertheless, there is evidence suggesting that prevention of various consequences of LBP is feasible. However, for those interventions where there is acceptable evidence, the effect sizes are rather modest. The most promising approaches seem to involve physical activity/exercise and appropriate (biopsychosocial) education, at least for adults. But, no single intervention is likely to be effective to prevent the overall problem of LBP, owing to its multidimensional nature. Prevention in LBP is a societal as well as an individual concern. So, optimal progress on prevention in LBP will likely require a cultural shift in the way LBP is viewed, its relationship with activity and work, how it might best be tackled, and just what is reasonable to expect from preventive strategies. It is important to get all the players onside, but innovative studies are required to understand better the mechanisms and delivery of prevention in LBP. Anecdotally, individuals may report that various strategies work for them, but in the absence of scientific evidence that does not mean they can be generally recommended for prevention, it is not known whether some of these strategies have disadvantageous long- term effects. Recommendations: These are based on systematic reviews, existing evidence-based guidelines, and scientific studies. The studies on which these recommendations are based were often variable and imprecise in specifying the interventions and outcomes investigated. Hence, it is not always possible to state exactly which outcomes will be influenced by a given intervention. Summary of recommendations for the general population: Physical exercise is recommended for prevention of sick leave due to LBP and for the occurrence or duration of further episodes (Level A). There is insufficient consistent evidence to recommend for or against any specific type or intensity of exercise (Level C). Information and education about back problems, if based on biopsychosocial principles, should be considered (Level C), but information and education focused principally on a biomedical or biomechanical model cannot be recommended (Level C). Back schools based on traditional biomedical/biomechanical information, advice and instruction are not recommended for prevention in LBP (Level A). High intensity programmes, which comprise both an educational/skills programme and exercises, can be recommended for patients with recurrent and persistent back pain (Level B). Lumbar supports or back belts are not recommended (Level A). There is no robust evidence for or against recommending any specific chair or mattress for prevention in LBP (Level C), though persisting symptoms may be reduced with a mediurn-firm rather than a hard mattress (Level C). There is no evidence to support recommending manipulative treatment for prevention in LBP (Level D). Shoe insoles are not recommended in the prevention of back problems (Level A). There is insufficient evidence to recommend for or against correction of leg length (Level D). Summary of recommendations for workers: Physical exercise is recommended in the prevention of LBP (Level A), for prevention of recurrence of LBP (Level A) and for prevention of recurrence of sick leave due to LBP (Level Q. There is insufficient evidence to recommend for or against any specific type or intensity of exercise (Level C). Back schools based on traditional biomedical/biomechanical information, advice and instruction are not recommended for prevention in LBP (Level A). There is insufficient evidence to recommend for or against psychosocial information delivered at the worksite (Level C), but information oriented toward promoting activity and improving coping may promote a positive shift in beliefs (Level C). Lumbar supports or back belts are not recommended (Level A). Shoe inserts/orthoses are not recommended (Level A). There is insufficient evidence to recommend for or against in-soles, soft shoes, soft flooring or antifatigue mats (Level D). Temporary modified work and ergonomic workplace adaptations can be recommended to facilitate earlier return to work for workers sick listed due to LBP (Level B). There is insufficient consistent evidence to recommended physical ergonomics interventions alone for prevention in LBP (Level C). There is some evidence that, to be successful, a physical ergonomics programme would need an organisational dimension and involvement of the workers (Level B); there is insufficient evidence to specify precisely the useful content of such interventions (Level C). There is insufficient consistent evidence to recommend stand-alone work organisational interventions (Level C), yet such interventions could, in principle, enhance the effectiveness of physical ergonomics programmes. Whilst multidimensional interventions at the workplace can be recommended (Level A), it is not possible to recommend which dimensions and in what balance. Summary of recommendations for school age: There is insufficient evidence to recommend for or against a generalized educational intervention for the prevention of LBP or its consequences in schoolchildren (Level C). Despite the intuitive appeal of the idea, there is no evidence that attempts to prevent LBP in schoolchildren will have any impact on LBP in adults (Level D). Summary of recommendations for further research: It is recommended that the following approaches are considered for further research into prevention in low back pain. Future studies need to be of high quality; where possible that should be in the form of randomised controlled trials. It is also recommended that standards of evidence criteria for efficacy, effectiveness and dissemination should be taken into account (Society for Prevention Research 2004). As a general recommendation, it is considered important that future studies include cost-benefit and risk-benefit analyses. General Studies are needed to determine how and by whom interventions are best delivered to specific target groups. Good quality RCTs are needed to determine the effectiveness of specific interventions aimed at specific risk /target groups. Misconceptions about back pain are shown to be widespread in adults, and they play a role in the development of long-term disability (Goubert et al. 2004). Further study is necessary to explore whether these misconceptions may be prevented by carefully selected and presented health promotion programmes, with the merit of demedicalising LBP. More information is needed to match types of interventions with specific/relevant outcomes. High quality studies are recommended into the effectiveness of specific furniture to justify or refute claims by commercial interests. Workers Good quality RCTs are needed to study the effectiveness of daily physical activity for prevention of LBP and for prevention of recurrence of LBP. In addition, the effectiveness of physical exercise as well as daily physical activity should be studied for prevention of (recurrence of) sick leave due to LBP. It is recommended to perform good quality RCTs on the role of information oriented toward reducing fear avoidance beliefs and improving coping strategies in the prevention of LBP. Good quality RCTs are urgently needed to study the effectiveness of physical, psychosocial and organisational ergonomic interventions on a large variety of outcomes, ranging from prevention of (recurrence of) LBP and prevention of (recurrence of) sick leave due to LBP up to compensable LBP. It is recommended to investigate whether effective interventions can be applied to all workers, irrespective of gender, age, seniority and/or past history of LBP. If the effective interventions have to be more tailor-made, the optimal approach for each relevant subgroup should be examined. School age RCTs evaluating the possible positive effects of preventive programmes and risk factor modifications at young age on adult LBP are advocated. From a physiological point of view, poor life style habits and prolonged static sitting during school age on unadjusted furniture may play a role in the origin of LBP: further study is appropriate to determine any effectiveness of school-based interventions (exercise/sport, desks/seating, backpacks/bags). Further study with a follow-up into adulthood is needed to evaluate whether or not the physical cumulative load experience on the lumbar spine (e.g. from heavy book-bag carrying or sitting on unadjusted furniture) during childhood and adolescence contributes to adult LBP. AN - WOS:000237742400003 AU - Burton, A. K. AU - Balague, F. AU - Cardon, G. AU - Eriksen, H. R. AU - Henrotin, Y. AU - Lahad, A. AU - Leclerc, A. AU - Muller, G. AU - van der Beek, A. J. AU - Pr, Cost B. Working Grp Guidelines DA - Mar DO - 10.1007/s00586-006-1070-3 N1 - Burton, A. K. Balague, F. Cardon, G. Eriksen, H. R. Henrotin, Y. Lahad, A. Leclerc, A. Muller, G. van der Beek, A. J. Burton, Kim/0000-0002-9462-2227 1432-0932 2 PY - 2006 SN - 0940-6719 SP - S136-S168 ST - Chapter 2 - European guidelines for prevention in low back pain T2 - European Spine Journal TI - Chapter 2 - European guidelines for prevention in low back pain UR - ://WOS:000237742400003 VL - 15 ID - 2738 ER - TY - JOUR AB - OBJECTIVE: To determine the prevalence of pain complaints, specifically of chronic widespread pain, in the general population; and to explore the utilization of health services by various pain groups. METHODS: Cross sectional population survey of 2210 adults in the southern part of Israel, who were classified into 5 pain groups: no pain, transient pain, chronic regional pain, chronic widespread pain, and other. Participants were interviewed about pain patterns and utilization of health services. RESULTS: Forty-four percent reported pain on the day of the interview. The prevalence of chronic widespread pain in the study population was 9.9%, 14% in women and 3% in men (p<0.01). The prevalence in the Israeli adult population was estimated after adjusting for sex and age as 10.2%. The prevalence of any chronic pain (regional or widespread) increased with age. The prevalence of chronic widespread pain was significantly higher in women than in men across all age groups (p<0.01). Persons with chronic widespread pain reported most frequent visits to their physicians (10.8 visits/year) and most frequent use of antiinflammatory and analgesic drugs. They were more frequently referred to specialists and tended to be hospitalized slightly more often. CONCLUSION: In the general population in Israel, widespread pain is common, and its prevalence is comparable with reports from USA, UK, and Canada. AD - Epidemiology Department, Ben-Gurion University of the Negev, and Soroka Medical Center, Beer-Sheva, Israel. AN - 10852282 AU - Buskila, D. AU - Abramov, G. AU - Biton, A. AU - Neumann, L. DA - Jun DP - NLM ET - 2000/06/14 IS - 6 KW - Absenteeism Adolescent Adult Age Distribution Aged Aged, 80 and over Analgesics/therapeutic use Chronic Disease Comorbidity Cross-Sectional Studies Female Hospitals/*statistics & numerical data Humans Israel/epidemiology Male Middle Aged Pain/drug therapy/*epidemiology Physicians' Offices/*statistics & numerical data Prevalence Sex Distribution LA - eng N1 - Buskila, D Abramov, G Biton, A Neumann, L Journal Article Canada J Rheumatol. 2000 Jun;27(6):1521-5. PY - 2000 SN - 0315-162X (Print) 0315-162x SP - 1521-5 ST - The prevalence of pain complaints in a general population in Israel and its implications for utilization of health services T2 - J Rheumatol TI - The prevalence of pain complaints in a general population in Israel and its implications for utilization of health services VL - 27 ID - 3389 ER - TY - JOUR AB - Objective: Our aim was to examine and map the consequences of chronic pain in children and adolescents. Method: A scoping review was carried out in the international databases (PubMed, SCOPUS, WOS and CINAHL, Cochrane Library) and gray literature. We included documents that addressed psychosocial aspects that influence chronic pain, published in English between 2010 and 2016. We excluded the documents that dealt with pharmacological treatments, chronic pain derived from surgical interventions or where there was no access to full text. 34 of the 716 documents reviewed were included. Results: Studies show that pain is associated with high rates of functional disability, sleep disorders and spectrum depression-anxiety. Young people experience higher rates of victimization and stigmatization, contributing to social isolation, difficulty in meeting academic demands and less opportunity to consume illegal substances. With respect to the family, chronic pain has been associated with poorer family functioning and considerable investment of economic resources. Conclusions: This Scoping Review shows that functional capacity, sleep, personal development, peer support and family functioning are interesting lines in published works. However, gaps in knowledge are detected in areas such as risk behaviours, the consequences that pain can cause in adulthood and gender inequalities. (C) 2018 SESPAS. Published by Elsevier Espana, This is an open access article under the CC BY-NC-ND license (http://creativecommons.orgilicenses/by-nc-nd/4.0/). AN - WOS:000465490700012 AU - Caceres-Matos, R. AU - Gil-Garcia, E. AU - Barrientos-Trigo, S. AU - Molina, E. AU - Porcel-Galvez, A. M. DA - May-Jun DO - 10.1016/j.gaceta.2017.11.007 IS - 3 N1 - Caceres-Matos, Rocio Gil-Garcia, Eugenia Barrientos-Trigo, Sergio Molina, Esther Maria Porcel-Galvez, Ana Barrientos-Trigo, Sergio/M-4640-2018; Molina, Esther/J-2847-2018; Galvez, Ana Maria Porcel/AAM-6081-2020; Gil-Garcia, Eugenia/K-5181-2017 Barrientos-Trigo, Sergio/0000-0001-7618-3091; Molina, Esther/0000-0002-0771-7608; Gil-Garcia, Eugenia/0000-0003-3862-6845 1578-1283 PY - 2019 SN - 0213-9111 SP - 272-282 ST - Consequences of chronic pain in childhood and adolescence T2 - Gaceta Sanitaria TI - Consequences of chronic pain in childhood and adolescence UR - ://WOS:000465490700012 VL - 33 ID - 1927 ER - TY - JOUR AB - OBJECTIVES: Treatment for childhood leukemia requires frequent lumbar punctures (LP) and bone marrow aspirations (BMA), often described by children and parents as more distressing than the disease itself. Findings in schoolchildren and chronic pain samples indicate that increased parental distress may increase parental protective, pain-attending behavior, which is associated with more child pain and distress. However, in the context of invasive medical procedures, it is unknown which parents are likely to become most distressed and engage in pain-attending behavior, and how this impacts the children's experiences. The present study investigated the impact of parental catastrophic thoughts upon parental distress and pain-attending behavior (verbal and nonverbal). Furthermore, the association between parental responses and the children's pain behavior, pain, and distress was examined. MATERIALS AND METHODS: A total of 46 parents of children with leukemia (range, 0.6 to 15 y) who underwent a LP/BMA procedure participated in this study. Parental catastrophizing was assessed before and parental and child distress was assessed after the LP/BMA procedure. Parental pain-attending behavior and the child's pain behavior were observed before and after the LP/BMA procedure. RESULTS: Findings indicated that heightened parental catastrophic thinking contributed to increased parental distress during LP/BMA and less pain-attending behavior before the LP/BMA procedure, especially in young children. In contrast, heightened distress in parents with high levels of catastrophizing contributed to increased engagement in postprocedural pain-attending behavior. For young children, increased preprocedural pain-attending behavior was related to more child distress, pain, and pain behavior. DISCUSSION: The findings demonstrate the importance of parental catastrophic thinking in understanding their caregiving responses and preparing parents and children for painful invasive medical procedures. AD - *Centre for Pediatric Pain Research, IWK Health Centre, Halifax, Nova Scotia, Canada †Department of Experimental-Clinical and Health Psychology, Ghent University ‡Department of Pediatric Oncology/Hematology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium. AN - 24042348 AU - Caes, L. AU - Vervoort, T. AU - Devos, P. AU - Verlooy, J. AU - Benoit, Y. AU - Goubert, L. DA - Sep DO - 10.1097/ajp.0000000000000028 DP - NLM ET - 2013/09/18 IS - 9 KW - Adolescent Adult Age Factors Bone Marrow Purging/adverse effects/psychology *Catastrophization Child Child, Preschool Female Humans Infant Leukemia/*physiopathology/psychology/therapy Male Middle Aged Pain/etiology/*physiopathology/psychology Parent-Child Relations Parents/*psychology Spinal Puncture/adverse effects/psychology *Stress, Psychological Young Adult LA - eng N1 - 1536-5409 Caes, Line Vervoort, Tine Devos, Patricia Verlooy, Joris Benoit, Yves Goubert, Liesbet Journal Article Research Support, Non-U.S. Gov't United States Clin J Pain. 2014 Sep;30(9):787-99. doi: 10.1097/AJP.0000000000000028. PY - 2014 SN - 0749-8047 SP - 787-99 ST - Parental distress and catastrophic thoughts about child pain: implications for parental protective behavior in the context of child leukemia-related medical procedures T2 - Clin J Pain TI - Parental distress and catastrophic thoughts about child pain: implications for parental protective behavior in the context of child leukemia-related medical procedures VL - 30 ID - 3979 ER - TY - JOUR AB - Background: The elderly population is growing in Turkey, as it is worldwide. The average age of residents in rural areas of Turkey is relatively high and is gradually increasing. The purpose of this study is to summarize the fitness and frailty of elderly adults living in a rural area of Turkey characterized by a relatively low level of socioeconomic development. Material/Methods: This study was designed as a prospective, cross-sectional study, and was conducted in a rural area of Kars Province. A total of 168 elderly adults (>= 65 years old) from 12 central villages were included in the study. The Fried Frailty Criteria was used to assess the frailty of the participants. In addition to frailty, the physical, social, and mental status of elderly adults was examined. Results: The prevalence of frailty in this rural area of Turkey was 7.1%. The study group ranged in age from 65 to 96 years (mean 72.70 +/- 7.73 years), and 53.6% were female. Among the elderly adult group, 84.3% had not completed elementary school, and 43.29% had a monthly income of <= 500 Turkish liras ($200). No significant relationship was identified between gender and frailty. There was a statistically significant relationship between frailty and older age, lower education level, lower economic level, co-morbidities, polypharmacy, diabetes, chronic obstructive pulmonary disease, gastric disease, arthritis, generalized pain, benign prostatic hyperplasia, urinary incontinence, auditory impairment, impaired oral care, caregiver burden, impaired cognitive function, depression, or a lack of social support (social isolation). Conclusions: It is believed that this study will contribute considerably to understanding the health status and needs of elderly adults in Turkey and the health problems of this population as well as to planning the development of public health and geriatric services based on regional needs. AN - WOS:000354416000001 AU - Cakmur, H. DA - Apr DO - 10.12659/msm.893400 N1 - Cakmur, Hulya PY - 2015 SN - 1643-3750 SP - 1232-1242 ST - Frailty Among Elderly Adults in a Rural Area of Turkey T2 - Medical Science Monitor TI - Frailty Among Elderly Adults in a Rural Area of Turkey UR - ://WOS:000354416000001 VL - 21 ID - 2238 ER - TY - JOUR AB - INTRODUCTION: Camine Con Gusto (CCG) is the Hispanic version of an evidence-based walking program for people with arthritis. This study examined CCG outcomes, feasibility, tolerability, safety, and acceptability and potential tailoring. METHOD: A pre and post 6-week evaluation was conducted in Hispanic people with arthritis. Outcomes included pain, stiffness, fatigue, functional capacity, helplessness, and self-efficacy. A formative evaluation with program participants and key stakeholders explored program tailoring. RESULTS: Participants' mean age was 46.9 years, 44.4% had a high school degree or less, 2.5% were born in United States, 60.1% spoke only Spanish, and 74.7% were female. Moderate effect sizes were found: 0.50 for pain, 0.75 for fatigue, 0.49 for stiffness, 0.33 for function, 0.26 for helplessness, and 0.24 for self-efficacy. There were 285 participants recruited with an 82% 6-week retention (feasibility), no adverse events were reported (safety), and 98% reported program satisfaction (acceptability). Recommended adaptations included simpler language, more pictures and content addressing nutrition and chronic conditions, shortened materials, and inclusion of motivational strategies. CONCLUSION: CCG showed improvement in outcomes in Hispanic individuals comparable to those noted in non-Hispanic White and Black individuals with arthritis. AD - University of North Carolina at Chapel Hill, NC, USA leigh_callahan@med.unc.edu. University of North Carolina at Chapel Hill, NC, USA. UNC Hospitals, Chapel Hill, NC, USA. AN - 27553228 AU - Callahan, L. F. AU - Rivadeneira, A. AU - Altpeter, M. AU - Vilen, L. AU - Cleveland, R. J. AU - Sepulveda, V. E. AU - Hackney, B. AU - Reuland, D. S. AU - Rojas, C. C2 - PMC5406131 C6 - NIHMS856328 DA - Sep DO - 10.1177/1540415316665202 DP - NLM ET - 2016/08/25 IS - 3 KW - Activities of Daily Living Adult Aged Aged, 80 and over Arthritis/complications/*therapy *Exercise Therapy *Fatigue Female *Hispanic Americans Humans Male Middle Aged *Pain Pain Management Program Evaluation *Range of Motion, Articular Self Efficacy United States *Walking Young Adult *chronic conditions *health disparities *health promotion *qualitative methods *quantitative methods of interest with respect to the research, authorship, and/or publication of this article. LA - eng N1 - 1938-8993 Callahan, Leigh F Rivadeneira, Alfredo Altpeter, Mary Vilen, Leigha Cleveland, Rebecca J Sepulveda, Victoria E Hackney, Betsy Reuland, Daniel S Rojas, Claudia TL1 TR001110/TR/NCATS NIH HHS/United States UL1 TR001111/TR/NCATS NIH HHS/United States UL1 TR002489/TR/NCATS NIH HHS/United States Evaluation Study Journal Article Hisp Health Care Int. 2016 Sep;14(3):132-40. doi: 10.1177/1540415316665202. Epub 2016 Aug 23. PY - 2016 SN - 1540-4153 (Print) 1540-4153 SP - 132-40 ST - Evaluation of the Arthritis Foundation's Camine Con Gusto Program for Hispanic Adults With Arthritis T2 - Hisp Health Care Int TI - Evaluation of the Arthritis Foundation's Camine Con Gusto Program for Hispanic Adults With Arthritis VL - 14 ID - 3883 ER - TY - JOUR AB - Background: Numerous studies have explored how patients and their caregivers cope with amyotrophic lateral sclerosis (ALS), but the literature completely lacks research on the psychological impact of the disease on patients' children. The aim of our study was to investigate the emotional and psychological impact of a parent with ALS on school-age children and adolescents in terms of problem behavior, adjustment, and personality characteristics. Methods: The study involved 23 children (mean age = 10.62 years, six females) with a parent suffering from ALS, and both their parents. Children were matched for age, gender, and birth-order with a control group of children with healthy parents. They were administered the Youth Self Report (YSR) questionnaire and the Rorschach Comprehensive System, and their healthy parent completed the Child Behavior Checklist (CBCL). Results: Findings clearly showed that, compared with controls, children with a parent who had ALS had several clinically significant adverse emotional and behavioral consequences, with emotional and behavioral problems, internalizing problems, anxiety and depressive symptoms. Children of a parent with ALS scored higher than controls for the Total Problems, Internalizing Problems, Anxious/Depressed and Withdrawn/Depressed scales in the YSR. A relevant percentage of children fell within the clinical range (42.9%) and borderline range (28.6%) for Internalizing Problems, The Rorschach CS confirmed the substantial impact of ALS in a parent on their offspring in terms of internalizing behavior and depression, with adjustment difficulties, psychological pain, and thought problems. Conclusion: Our findings indicate that school-aged children and adolescents with a parent who has ALS are vulnerable and carry a substantially higher risk of internalizing behavior, depressive symptoms, and reactive problems than children with healthy parents. Families affected may need support to cope with such an overwhelming disease. AN - WOS:000351099300001 AU - Calvo, V. AU - Bianco, F. AU - Benelli, E. AU - Sambin, M. AU - Monsurro, M. R. AU - Femiano, C. AU - Querin, G. AU - Soraru, G. AU - Palmieri, A. C7 - 288 DA - Mar DO - 10.3389/fpsyg.2015.00288 N1 - Calvo, Vincenzo Bianco, Francesca Benelli, Enrico Sambin, Marco Monsurro, Maria R. Femiano, Cinzia Querin, Giorgia Soraru, Gianni Palmieri, Arianna Calvo, Vincenzo/H-9090-2012; Benelli, Enrico/AAV-8667-2020; Soraro, Gianni/AAB-8891-2019 Calvo, Vincenzo/0000-0002-9828-0551; Benelli, Enrico/0000-0003-2549-2884; Soraru, Gianni/0000-0001-9691-6328; PALMIERI, Arianna/0000-0003-0453-001X PY - 2015 SN - 1664-1078 ST - Impact on children of a parent with ALS: a case-control study T2 - Frontiers in Psychology TI - Impact on children of a parent with ALS: a case-control study UR - ://WOS:000351099300001 VL - 6 ID - 2243 ER - TY - JOUR AB - Despite strong evidence that skin-to-skin contact and breast-feeding are effective pain-relieving interventions for infants undergoing painful procedures, they remain underutilized in clinical practice. Given the important contribution of parents, there is a need to find innovative ways to assist parents to become actively involved in their infant's care. We developed a YouTube video to disseminate evidence-based information on the effectiveness of skin-to-skin contact and breast-feeding for infant pain management. The 2-minute 39-second video launched on December 2, 2014, and was promoted through Web-based and in-person communication and YouTube advertisements. Data were collected using YouTube analytics and an online survey. Post-18 months from its launch, the video had a reach of 157 938 views from 154 countries, with most viewers watching an average of 73% of the video (1 minute 56 seconds). Parents (n = 32) and healthcare providers (n = 170) completed the survey. Overall, both reported that they liked the video, found it helpful, felt more confident, and were more likely to use skin-to-skin contact (16% and 12%) and breast-feeding (3% and 11%), respectively, during future painful procedures. Despite the high-viewing patterns, alternative methods should be considered to better evaluate the impact on practice change. AN - WOS:000415074200013 AU - Campbell-Yeo, M. AU - Dol, J. AU - Disher, T. AU - Benoit, B. AU - Chambers, C. T. AU - Sheffield, K. AU - Boates, T. AU - Harrison, D. AU - Hewitt, B. AU - Jangaard, K. AU - Stinson, J. AU - Taddio, A. AU - Parker, J. A. AU - Caddell, K. DA - Oct-Dec DO - 10.1097/jpn.0000000000000263 IS - 4 N1 - Campbell-Yeo, Marsha Dol, Justine Disher, Timothy Benoit, Britney Chambers, Christine T. Sheffield, Kaitlyn Boates, Talia Harrison, Denise Hewitt, Brenda Jangaard, Krista Stinson, Jennifer Taddio, Anna Parker, Jennifer A. Caddell, Kim Chambers, Christine T./ABA-9257-2020; Harrison, Denise/N-6684-2017 Chambers, Christine T./0000-0002-7138-916X; Harrison, Denise/0000-0001-7549-7742; Parker, Jennifer/0000-0001-9900-4703; Dol, Justine/0000-0002-8928-7647; Campbell-Yeo, Marsha/0000-0001-6645-2809 1550-5073 PY - 2017 SN - 0893-2190 SP - 341-349 ST - The Power of a Parent's Touch: Evaluation of Reach and Impact of a Targeted Evidence-Based YouTube Video T2 - Journal of Perinatal & Neonatal Nursing TI - The Power of a Parent's Touch: Evaluation of Reach and Impact of a Targeted Evidence-Based YouTube Video UR - ://WOS:000415074200013 VL - 31 ID - 2071 ER - TY - JOUR AB - Objectives: To determine the psychosocial correlates of recurrent pediatric pain and its relationship to health service use and medical presentations for "unexplained" symptoms in primary care. Study design: Children 4 to 15 years of age who complained frequently of aches and pains to parents were compared with those with infrequent or no pain on measures of demographics, psychopathology, school attendance and performance, perceived health, and service use. Univariate analysis was followed by logistic regression. Results: Children who complained often of aches and pains used more health services, had more psychosocial problems, missed more school, and did worse academically. After controlling for health service use and demographics, recurrent pain was significantly associated with negative parental perceptions of child health and the presence of internalizing psychiatric symptoms. Higher levels of ambulatory health service use were associated with negative perceptions of child health, recurrent pain, visits for "unexplained" symptoms, and internalizing psychiatric symptoms. Conclusions: Pediatric recurrent pain challenges traditional service delivery models characterized by segregated systems of care for physical and mental disorders. Longitudinal and psychobiological studies of the relationship between recurrent pain, internalizing psychopathology, and health beliefs are warranted to direct future treatment efforts. (J Pediatr 2002;141:76-83). AN - WOS:000176849800015 AU - Campo, J. V. AU - Comer, D. M. AU - Jansen-McWilliams, L. AU - Gardner, W. AU - Kelleher, K. J. DA - Jul DO - 10.1067/mpd.2002.125491 IS - 1 N1 - Campo, JV Comer, DM Jansen-McWilliams, L Gardner, W Kelleher, KJ Kelleher, Kelly/E-3361-2011 1097-6833 PY - 2002 SN - 0022-3476 SP - 76-83 ST - Recurrent pain, emotional distress, and health service use in childhood T2 - Journal of Pediatrics TI - Recurrent pain, emotional distress, and health service use in childhood UR - ://WOS:000176849800015 VL - 141 ID - 2828 ER - TY - JOUR AB - It is unknown whether children with functional gastrointestinal (GI) disorders identify specific foods that exacerbate their GI symptoms. The objectives of this study were to determine the perceived role of food on GI symptoms and to determine the impact of food-induced symptoms on quality of life (QOL) in children with functional GI disorders. Between August and November 2010, 25 children ages 11 to 17 years old with functional GI disorders, and a parent completed a food symptom association questionnaire and validated questionnaires assessing FGID symptoms and QOL. In addition, children completed a 24-hour food recall, participated in focus groups to identify problematic foods and any coping strategies, and discussed how their QOL was affected. Statistical analyses were conducted using chi 2, t test, Mann-Whitney U test, Wilcoxon signed rank, and Spearman's rho. Children identified a median of 11 (range=2 to 25) foods as exacerbating a GI symptom, with the most commonly identified foods being spicy foods, cow's milk, and pizza. Several coping strategies were identified, including consuming smaller portions, modifying foods, and avoiding a median of 8 (range=1 to 20) foods. Children reported that food-induced symptoms interfered with school performance, sports, and social activities. Although the parent's assessment of their child's QOL negatively correlated with the number of perceived symptom-inducing foods in their child, this relationship was not found in the children. Findings suggest that specific foods are perceived to exacerbate GI symptoms in children with functional GI disorders. In addition, despite use of several coping strategies, food-induced symptoms can adversely impact children's QOL in several important areas. AN - WOS:000332501100009 AU - Carlson, M. J. AU - Moore, C. E. AU - Tsai, C. M. AU - Shulman, R. J. AU - Chumpitazi, B. P. DA - Mar DO - 10.1016/j.jand.2013.10.013 IS - 3 N1 - Carlson, Michelle J. Moore, Carolyn E. Tsai, Cynthia M. Shulman, Robert J. Chumpitazi, Bruno P. 2212-2680 PY - 2014 SN - 2212-2672 SP - 403-413 ST - Child and Parent Perceived Food-Induced Gastrointestinal Symptoms and Quality of Life in Children with Functional Gastrointestinal Disorders T2 - Journal of the Academy of Nutrition and Dietetics TI - Child and Parent Perceived Food-Induced Gastrointestinal Symptoms and Quality of Life in Children with Functional Gastrointestinal Disorders UR - ://WOS:000332501100009 VL - 114 ID - 2315 ER - TY - JOUR AB - The purpose of the study was to determine the prevalence of recurrent headaches among schoolchildren in Goteborg and the relation of headache to school and family variables. A stratified sample of 1297 pupils was selected to be representative of the Goteborg population. Data were obtained by means of questionnaires. Twenty-six per cent had ''headache once a month or more'' and 6% had ''headache several times a week or daily'' (frequent headache). There was a gradual increase of headache with age. In the third grade there was a marked increase of frequent headache. In the highest school level (grades 7-9), girls had significantly more headache than boys. In the lower school level (grades 1-3), a greater number of pupils in the class increases the risk of frequent headache. Pupil in the intermediate school level (grades 4-6) reported more frequent headache in districts with high unemployment. It is concluded that headache among schoolchildren is a health problem which merits increased attention. AN - WOS:A1996UV57900012 AU - Carlsson, J. DA - Jun DO - 10.1111/j.1651-2227.1996.tb14128.x IS - 6 N1 - Carlsson, J PY - 1996 SN - 0803-5253 SP - 692-696 ST - Prevalence of headache in schoolchildren: Relation to family and school factors T2 - Acta Paediatrica TI - Prevalence of headache in schoolchildren: Relation to family and school factors UR - ://WOS:A1996UV57900012 VL - 85 ID - 2927 ER - TY - JOUR AB - OBJECTIVE. Increasing evidence confirms a strict relationship between mental disorders and physical health. Particularly, stressful life events and post-traumatic stress disorder (PTSD) have been closely correlated with various physical disorders and somatic symptoms, such as chronic pain, gastrointestinal disorders, and headaches. The aim of this study was to investigate the emergence of somatic symptoms in a sample of young adult survivors 21 months after exposure to the L'Aquila 2009 earthquake, with particular attention to PTSD and gender impact. METHODS. Four hundred and fifty high-school senior students (253 male and 197 female) exposed to the 2009 L'Aquila earthquake, 21 months earlier, were enrolled and evaluated by the Trauma and Loss Spectrum Self-Report (TALS-SR), for symptomatological PTSD, and the Mood Spectrum Self-Report-Lifetime Version (MOODS-SR) "rhythmicity and vegetative functions" domain, for somatic symptoms. RESULTS. Significantly higher rates of endorsement of the MOODS-SR somatic symptoms emerged in survivors with PTSD compared to those without. Females reported higher rates of endorsement of at least one MOODS-SR somatic symptom compared to males; however, a Decision Tree model and a two-way analysis of variance model confirmed a significant effect of PTSD only. A multivariate logistical regression showed a significant association between the presence of at least one MOOD-SR somatic symptom and re-experiencing and maladaptive coping TALS-SR domains. CONCLUSION. This study corroborates a relevant impact of symptomatological PTSD, across both the genders, on somatic symptoms occurring in young adults after months from exposure to a massive earthquake. AD - Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy. Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy. AN - 32248878 AU - Carmassi, C. AU - Dell'Oste, V. AU - Barberi, F. M. AU - Pedrinelli, V. AU - Cordone, A. AU - Cappelli, A. AU - Cremone, I. M. AU - Rossi, R. AU - Bertelloni, C. A. AU - Dell'Osso, L. DA - Apr 6 DO - 10.1017/s1092852920000097 DP - NLM ET - 2020/04/07 KW - Dsm-5 Post-traumatic stress disorder (PTSD) gastrointestinal diseases migraine natural disaster painful stimuli hypo- or hypersensitivity LA - eng N1 - Carmassi, Claudia Dell'Oste, Valerio Orcid: 0000-0003-0520-4785 Barberi, Filippo M Pedrinelli, Virginia Cordone, Annalisa Cappelli, Andrea Cremone, Ivan M Rossi, Rodolfo Bertelloni, Carlo A Dell'Osso, Liliana Journal Article United States CNS Spectr. 2020 Apr 6:1-7. doi: 10.1017/S1092852920000097. PY - 2020 SN - 1092-8529 (Print) 1092-8529 SP - 1-7 ST - Do somatic symptoms relate to PTSD and gender after earthquake exposure? A cross-sectional study on young adult survivors in Italy T2 - CNS Spectr TI - Do somatic symptoms relate to PTSD and gender after earthquake exposure? A cross-sectional study on young adult survivors in Italy ID - 4185 ER - TY - JOUR AB - Background: Increasing evidence indicates that survivors to traumatic events may show disruption of sleep pattern, eating and sexual behaviors, and somatic symptoms suggestive of alterations of biorhythmicity and vegetative functions. Therefore, the aim of this study was to investigate these possible alterations in a sample of survivors in the aftermath of earthquake exposure, with particular attention to gender differences and impact of post-traumatic stress disorder (PTSD). Methods: High school senior students, who had been exposed to the 2009 L'Aquila earthquake, were enrolled 21 months after the traumatic event and evaluated by the Trauma and Loss Spectrum Self-Report to investigate PTSD rates and by a domain of the Mood Spectrum Self-Report-Lifetime Version (MOODS-SR), to explore alterations in circadian/seasonal rhythms and vegetative functions. Results: The rates of endorsement of MOODS-SR rhythmicity and vegetative functions domain and subdomain scores were significantly higher in survivors with PTSD with respect to those without it. Among all earthquake survivors, women reported higher scores than men on the rhythmicity and vegetative functions domain and subdomain scores, except for the rhythmicity and sexual functions ones. Female survivors without PTSD showed significantly higher scores than men in the rhythmicity and vegetative functions total scores and the sleep and weight and appetite subdomains. Potentially traumatic events burden predicted rhythmicity and vegetative functions impairment, with a moderation effect of re-experiencing symptoms. Conclusions: We report impairments in rhythmicity, sleep, eating, and sexual and somatic health in survivors to a massive earthquake, particularly among subjects with PTSD and higher re-experiencing symptoms, with specific gender-related differences. Evaluating symptoms of impaired rhythmicity and vegetative functions seems essential for a more accurate assessment and clinical management of survivors to a mass trauma. AN - WOS:000593962700001 AU - Carmassi, C. AU - Dell'Oste, V. AU - Bertelloni, C. A. AU - Foghi, C. AU - Diadema, E. AU - Mucci, F. AU - Massimetti, G. AU - Rossi, A. AU - Dell'Osso, L. C7 - 492006 DA - Nov DO - 10.3389/fpsyt.2020.492006 N1 - Carmassi, Claudia Dell'Oste, Valerio Bertelloni, Carlo Antonio Foghi, Claudia Diadema, Elisa Mucci, Federico Massimetti, Gabriele Rossi, Alessandro Dell'Osso, Liliana Dell'Oste, Valerio/ABE-3538-2020 Dell'Oste, Valerio/0000-0003-0520-4785 PY - 2020 SN - 1664-0640 ST - Disrupted Rhythmicity and Vegetative Functions Relate to PTSD and Gender in Earthquake Survivors T2 - Frontiers in Psychiatry TI - Disrupted Rhythmicity and Vegetative Functions Relate to PTSD and Gender in Earthquake Survivors UR - ://WOS:000593962700001 VL - 11 ID - 1784 ER - TY - JOUR AB - Several epidemiological studies have shown the presence of comorbidity between various types of sleep disorders and different headache subtypes. Migraine without aura is a sensitive risk factor for disorders of initiating and maintaining sleep (odds ratio (OR) 8.2500), and chronic tension-type headache for sleep breathing disorders (OR 15.231), but headache disorder is a cumulative risk factor for disorders of excessive somnolence (OR 15.061). This result has not been reported in the clinical literature. AU - Carotenuto, Marco AU - Guidetti, Vincenzo AU - Ruju, Francesca AU - Galli, Federica AU - Tagliente, Francesca R. AU - Pascotto, Antonio DA - 2005/09// DO - 10.1007/s10194-005-0204-z DP - PubMed IS - 4 J2 - J Headache Pain KW - Child Child, Preschool Circadian Rhythm Comorbidity Headache Disorders Humans Risk Factors Sleep Stages Sleep Wake Disorders LA - eng PY - 2005 SN - 1129-2369 SP - 268-270 ST - Headache disorders as risk factors for sleep disturbances in school aged children T2 - The Journal of Headache and Pain TI - Headache disorders as risk factors for sleep disturbances in school aged children UR - http://www.ncbi.nlm.nih.gov/pubmed/16362683 VL - 6 ID - 130 ER - TY - JOUR AB - This review updates a similar paper published in the Journal of Family Therapy in 2001. It presents evidence from meta-analyses, systematic literature reviews and controlled trials for the effectiveness of systemic interventions for families of children and adolescents with various difficulties. In this context, systemic interventions include both family therapy and other family-based approaches such as parent training. The evidence supports the effectiveness of systemic interventions either alone or as part of multimodal programmes for sleep, feeding and attachment problems in infancy; child abuse and neglect; conduct problems (including childhood behavioural difficulties, ADHD, delinquency and drug abuse); emotional problems (including anxiety, depression, grief, bipolar disorder and suicidality); eating disorders (including anorexia, bulimia and obesity); and somatic problems (including enuresis, encopresis, recurrent abdominal pain, and poorly controlled asthma and diabetes). AN - WOS:000261979500002 AU - Carr, A. DA - Feb DO - 10.1111/j.1467-6427.2008.00451.x IS - 1 N1 - Carr, Alan Carr, Alan/0000-0003-4563-8852 1467-6427 PY - 2009 SN - 0163-4445 SP - 3-45 ST - The effectiveness of family therapy and systemic interventions for child-focused problems T2 - Journal of Family Therapy TI - The effectiveness of family therapy and systemic interventions for child-focused problems UR - ://WOS:000261979500002 VL - 31 ID - 2617 ER - TY - JOUR AB - Background: Little is known about lower back complaints in adolescent competitive alpine skiers. This study assessed their prevalence and severity (i.e., intensity and disability) with respect to sex, category, discipline preference, and training attributes. Methods: 188 competitive skiers aged 15 to 18 years volunteered in this study. Data collection included (i) questions on participants' demographics, sports exposure, discipline preferences, and other sports-related practices; (ii) the Nordic Musculoskeletal Questionnaire on lower back complaints; and (iii) the Graded Chronic Pain Scale. Results: As many as 80.3% and 50.0% of all skiers suffered from lower back complaints during the last 12 months and 7 days, respectively. A total of 50.7% reported their complaints to be attributable to slalom skiing, and 26% to giant slalom. The majority of complaints were classified as low intensity/low disability (Grade I, 57.4%) and high intensity/low disability complaints (Grade II, 21.8%). The Characteristic Pain Intensity was found to be significantly related to the skiers' years of sports participation, number of competitions/season, and number of skiing days/season. Conclusion: This study further supports the relatively high magnitudes of lower back-related pain in adolescent competitive alpine skiers, with a considerable amount of high intensity (but low disability) complaints, and training attributes being a key driver. AN - WOS:000588905700001 AU - Carraro, A. AU - Gnech, M. AU - Sarto, F. AU - Sarto, D. AU - Sporri, J. AU - Masiero, S. C7 - 7408 DA - Nov DO - 10.3390/app10217408 IS - 21 N1 - Carraro, Attilio Gnech, Martina Sarto, Fabio Sarto, Diego Spoerri, Joerg Masiero, Stefano Sarto, Fabio/AAP-7652-2021 Sarto, Fabio/0000-0001-8572-5147; Sporri, Jorg/0000-0002-0353-1021; Masiero, Stefano/0000-0002-0361-4898 2076-3417 PY - 2020 ST - Lower Back Complaints in Adolescent Competitive Alpine Skiers: A Cross-Sectional Study T2 - Applied Sciences-Basel TI - Lower Back Complaints in Adolescent Competitive Alpine Skiers: A Cross-Sectional Study UR - ://WOS:000588905700001 VL - 10 ID - 1790 ER - TY - JOUR AB - OBJECTIVES: To evaluate the lifetime prevalence of migraine and other headaches lasting 4 or more hours in a population-based study of older adults. BACKGROUND: Migraine and other headaches not fulfilling migraine criteria are common afflictions. Yet the health and social effects of these conditions have not been fully appreciated, particularly among older adults. METHODS: The study included 12 750 participants in the Atherosclerosis Risk in Communities (ARIC) Study from 4 US communities. Prevalence estimates of a lifetime history of migraine and other headaches lasting 4 or more hours were obtained for race and gender groups. A cross-sectional analysis was done to assess the relationship between headache type, by aura status, and various sociodemographic and health-related indices. RESULTS: Compared to education beyond high school, having completed less than 12 years of education was significantly associated with an increased occurrence of migraine with aura (prevalence odds ratio [POR], 1.47; 95% confidence interval [CI], 1.08 to 2.01). Family income less than $16 000, compared to family income of $75 000 or greater, was significantly associated with migraine with aura (POR, 1.68; 95% CI, 1.07 to 2.64), migraine without aura (POR, 1.56; 95% CI, 1.14 to 2.14), and other headaches with aura (POR, 1.89; 95% CI, 1.14 to 3.13). The prevalence odds ratio was higher in each headache category, particularly for those with an aura, for those with hypertension versus normotension and for those who perceived their general health as poor compared to those whose perception was excellent. CONCLUSIONS: A lifetime history of migraine with aura and other headaches with aura was more common among whites, women, and younger participants. Further investigation of headaches lasting 4 or more hours, particularly by aura status, is warranted. AD - Department of Epidemiology, University of North Carolina at Chapel Hill, USA. AN - 14979879 AU - Carson, A. P. AU - Rose, K. M. AU - Sanford, C. P. AU - Ephross, S. A. AU - Stang, P. E. AU - Hunt, K. J. AU - Brown, C. A. AU - Szklo, M. DA - Jan DO - 10.1111/j.1526-4610.2004.04005.x DP - NLM ET - 2004/02/26 IS - 1 KW - Aged Cohort Studies Female Headache/*epidemiology Humans Male Middle Aged Migraine Disorders/*epidemiology/etiology Prevalence Time Factors United States/epidemiology LA - eng N1 - Carson, April Perry Rose, Kathryn M Sanford, Catherine P Ephross, Sara A Stang, Paul E Hunt, Kelly J Brown, C Andrew Szklo, Moyses 5T32-HL-07055/HL/NHLBI NIH HHS/United States N01-HC-55018/HC/NHLBI NIH HHS/United States Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. United States Headache. 2004 Jan;44(1):20-8. doi: 10.1111/j.1526-4610.2004.04005.x. PY - 2004 SN - 0017-8748 (Print) 0017-8748 SP - 20-8 ST - Lifetime prevalence of migraine and other headaches lasting 4 or more hours: the Atherosclerosis Risk in Communities (ARIC) study T2 - Headache TI - Lifetime prevalence of migraine and other headaches lasting 4 or more hours: the Atherosclerosis Risk in Communities (ARIC) study VL - 44 ID - 3788 ER - TY - JOUR AB - OBJECTIVE: Our objective was to demonstrate that, despite recognition by both the gastroenterology and headache communities, abdominal migraine (AM) is an under-diagnosed cause of chronic, recurrent, abdominal pain in childhood in the USA. BACKGROUND: Chronic, recurrent abdominal pain occurs in 9-15% of all children and adolescents. After exclusion of anatomic, infectious, inflammatory, or other metabolic causes, "functional abdominal pain" is the most common diagnosis of chronic, idiopathic, abdominal pain in childhood. Functional abdominal pain is typically categorized into one, or a combination of, the following 4 groups: functional dyspepsia, irritable bowel syndrome, AM, or functional abdominal pain syndrome. International Classification of Headache Disorders--(ICHD-2) defines AM as an idiopathic disorder characterized by attacks of midline, moderate to severe abdominal pain lasting 1-72 hours with vasomotor symptoms, nausea and vomiting, and included AM among the "periodic syndromes of childhood that are precursors for migraine." Rome III Gastroenterology criteria (2006) separately established diagnostic criteria and confirmed AM as a well-defined cause of recurrent abdominal pain. METHODS: Following institutional review board approval, a retrospective chart review was conducted on patients referred to an academic pediatric gastroenterology practice with the clinical complaint of recurrent abdominal pain. ICHD-2 criteria were applied to identify the subset of children fulfilling criteria for AM. Demographics, diagnostic evaluation, treatment regimen and outcomes were collected. RESULTS: From an initial cohort of 600 children (ages 1-21 years; 59% females) with recurrent abdominal pain, 142 (24%) were excluded on the basis of their ultimate diagnosis. Of the 458 patients meeting inclusion criteria, 1824 total patient office visits were reviewed. Three hundred eighty-eight (84.6%) did not meet criteria for AM, 20 (4.4%) met ICHD-2 formal criteria for AM and another 50 (11%) had documentation lacking at least 1 criterion, but were otherwise consistent with AM (probable AM). During the observation period, no children seen in this gastroenterology practice had received a diagnosis of AM. CONCLUSION: Among children with chronic, idiopathic, recurrent abdominal pain, AM represents about 4-15%. Given the spectrum of treatment modalities now available for pediatric migraine, increased awareness of cardinal features of AM by pediatricians and pediatric gastroenterologists may result in improved diagnostic accuracy and early institution of both acute and preventative migraine-specific treatments. AD - Division of Pediatric Neurology, Children's Hospital of The King's Daughters, Eastern Virginia Medical Neurology School, Norfolk, VA 23509, USA. AN - 21395574 AU - Carson, L. AU - Lewis, D. AU - Tsou, M. AU - McGuire, E. AU - Surran, B. AU - Miller, C. AU - Vu, T. A. DA - May DO - 10.1111/j.1526-4610.2011.01855.x DP - NLM ET - 2011/03/15 IS - 5 KW - Abdominal Pain/classification/*complications/*epidemiology Adolescent Child Child, Preschool Female Humans Infant Male Migraine Disorders/classification/*complications/*epidemiology Prevalence United States/epidemiology Young Adult LA - eng N1 - 1526-4610 Carson, Laura Lewis, Donald Tsou, Marc McGuire, Erin Surran, Brooke Miller, Crystal Vu, Thuy-Anh Journal Article United States Headache. 2011 May;51(5):707-12. doi: 10.1111/j.1526-4610.2011.01855.x. Epub 2011 Mar 11. PY - 2011 SN - 0017-8748 SP - 707-12 ST - Abdominal migraine: an under-diagnosed cause of recurrent abdominal pain in children T2 - Headache TI - Abdominal migraine: an under-diagnosed cause of recurrent abdominal pain in children VL - 51 ID - 3109 ER - TY - JOUR AB - Chronic pain in children and adolescents is associated with major disruption to developmental experiences crucial to personal adjustment, quality of life, academic, vocational and social success. Caring for these patients involves understanding cognitive, affective, social and family dynamic factors associated with persistent pain syndromes. Evaluation and treatment necessitate a comprehensive multimodal approach including psychological and behavioral interventions that maximize return to more developmentally appropriate physical, academic and social activities. This article will provide an overview of major psychosocial factors impacting on pediatric pain and disability, propose an explanatory model for conceptualizing the development and maintenance of pain and functional disability in medically difficult-to-explain pain syndromes, and review representative evidence-based cognitive behavioral and systemic treatment approaches for improving functioning in this pediatric population. AN - WOS:000307334700001 AU - Carter, B. D. AU - Threlkeld, B. M. C7 - 15 DA - Jun DO - 10.1186/1546-0096-10-15 N1 - Carter, Bryan D. Threlkeld, Brooke M. 1546-0096 PY - 2012 ST - Psychosocial perspectives in the treatment of pediatric chronic pain T2 - Pediatric Rheumatology TI - Psychosocial perspectives in the treatment of pediatric chronic pain UR - ://WOS:000307334700001 VL - 10 ID - 2426 ER - TY - JOUR AB - Introduction: Although infrequently recorded in electronic health records (EHRs), measures of SES are essential to describe health inequalities and account for confounding in epidemiologic research. Medical Assistance (i.e., Medicaid) is often used as a surrogate for SES, but correspondence between conventional SES and Medical Assistance has been insufficiently studied. Methods: GeisingerClinic EHRdata from2001 to 2014 and a 2014 questionnaire were used to create six SES measures: EHR-derived Medical Assistance and proportion of time under observation on Medical Assistance; educational attainment, income, and marital status; and area-level poverty. Analyzed in 2016-2017, associations of SES measures with obesity, hypertension, type 2 diabetes, chronic rhinosinusitis, fatigue, and migraine headache were assessed using weighted age-and sex-adjusted logistic regression. Results: Among 5,550 participants (interquartile range, 39.6-57.5 years, 65.9% female), 83% never used Medical Assistance. All SES measures were correlated (Spearman's p= 0.4). Medical Assistance was significantly associated with all six health outcomes in adjusted models. For example, the OR for prevalent type 2 diabetes associated with Medical Assistance was 1.7 (95% CI = 1.3, 2.2); the OR for high school versus college graduates was 1.7 (95% CI = 1.2, 2.5). Medical Assistance was an imperfect proxy for SES: associations between conventional SES measures and health were attenuated <20% after adjustment for Medical Assistance. Conclusions: Because systematically collected SES measures are rarely available in EHRs and are unlikely to appear soon, researchers can use EHR-based Medical Assistance to describe inequalities. As SES has many domains, researchers who use Medical Assistance to evaluate the association of SES with health should expect substantial unmeasured confounding. (C) 2017 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved. AN - WOS:000425297700016 AU - Casey, J. A. AU - Pollak, J. AU - Glymour, M. M. AU - Mayeda, E. R. AU - Hirsch, A. G. AU - Schwartz, B. S. DA - Mar DO - 10.1016/j.amepre.2017.10.004 IS - 3 N1 - Casey, Joan A. Pollak, Jonathan Glymour, M. Maria Mayeda, Elizabeth R. Hirsch, Annemarie G. Schwartz, Brian S. Casey, Joan A./H-6405-2019 Casey, Joan A./0000-0002-9809-4695 1873-2607 PY - 2018 SN - 0749-3797 SP - 430-439 ST - Measures of SES for Electronic Health Record-based Research T2 - American Journal of Preventive Medicine TI - Measures of SES for Electronic Health Record-based Research UR - ://WOS:000425297700016 VL - 54 ID - 2030 ER - TY - JOUR AB - Children and adolescents spend most of their time at school. Therefore, teachers could be of help to improve the quality of life of students with chronic pain while they are at school. The aim of this study was to identify teachers' educational needs and resources to help improve the adjustment to and function in the school of students with chronic pain. A Delphi survey including two rounds was conducted. Overall, 49 needs were identified in the first round. They were related to education, training, organization/logistics, and communication with the family and the health care center. Among the most important needs, based on the importance given and consensus reached, were (1) having information about the most appropriate attitudes and responses to a student with chronic pain, (2) how to reduce absenteeism, (3) how to ease the return to school after a long absence due to his or her pain problem, and (4) how to establish effective communication with the family. The results of this study provide new important data on the educational needs and resources which teachers would like to have to help their students with chronic pain at school, which could be used to develop educative programs for teachers. AN - WOS:000645316300001 AU - Castarlenas, E. AU - Roy, R. AU - Salvat, I. AU - Monteso-Curto, P. AU - Miro, J. C7 - 4510 DA - Apr DO - 10.3390/su13084510 IS - 8 N1 - Castarlenas, Elena Roy, Ruben Salvat, Isabel Monteso-Curto, Pilar Miro, Jordi 2071-1050 PY - 2021 ST - Educational Needs and Resources for Teachers Working with Students with Chronic Pain: Results of a Delphi Study T2 - Sustainability TI - Educational Needs and Resources for Teachers Working with Students with Chronic Pain: Results of a Delphi Study UR - ://WOS:000645316300001 VL - 13 ID - 1745 ER - TY - JOUR AB - The purpose of this study is to determine whether there are some differences in the treatment responses to a multidisciplinary fibromyalgia (FM) treatment related with the baseline body mass index (BMI) of the participants. Inclusion criteria consisted of female sex, a diagnosis of FM (American College of Rheumatology criteria), age between 18 and 60 years, and between 3 and 8 years of schooling. Baseline BMI was determined, and patients were randomly assigned to one of the two treatment conditions: conventional pharmacologic treatment or multidisciplinary treatment. Outcome measures were pain intensity, functionality, catastrophizing, psychological distress, health-related quality of life, and sleep disturbances. One hundred thirty patients participated in the study. No statistical significant differences regarding pre-treatment outcomes were found among the different BMI subgroups, and between the two experimental conditions for each BMI category. General linear model analysis showed a significant interaction group treatment × time in pain intensity (p < .01), functionality (p < .0001), catastrophizing (p < .01), psychological distress (p < .0001), sleep index problems (p < .0001), and health-related quality of life (p < .05). No significant interactions were found in BMI × time, and in BMI × group treatment × time. There are not differences among normal weight, overweight and obese patients with FM regarding their response to a multidisciplinary treatment programme for FM which combines pharmacological treatment, education, physical therapy and cognitive behavioural therapy. AD - Pain Clinic, Hospital Universitari de Tarragona Joan XXIII, C/Doctor Mallafré Guasch, 4, 43007, Tarragona, Spain, antonicastel.hj23.ics@gencat.cat. AN - 25080875 AU - Castel, A. AU - Castro, S. AU - Fontova, R. AU - Poveda, M. J. AU - Cascón-Pereira, R. AU - Montull, S. AU - Padrol, A. AU - Qanneta, R. AU - Rull, M. DA - Feb DO - 10.1007/s00296-014-3096-x DP - NLM ET - 2014/08/02 IS - 2 KW - Adolescent Adult Analgesics/*therapeutic use Antidepressive Agents/*therapeutic use Body Mass Index Catastrophization/complications/psychology *Cognitive Behavioral Therapy Combined Modality Therapy Female Fibromyalgia/complications/psychology/*therapy Humans Hypnotics and Sedatives/*therapeutic use Middle Aged Obesity/*complications Overweight/complications Pain Measurement Patient Care Team *Physical Therapy Modalities Prognosis Quality of Life Sleep Wake Disorders/complications Stress, Psychological/complications/psychology Treatment Outcome Young Adult LA - eng N1 - 1437-160x Castel, Antoni Castro, Sonia Fontova, Ramon Poveda, Maria José Cascón-Pereira, Rosalia Montull, Salvador Padrol, Anna Qanneta, Rami Rull, Maria Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't Germany Rheumatol Int. 2015 Feb;35(2):303-14. doi: 10.1007/s00296-014-3096-x. Epub 2014 Aug 1. PY - 2015 SN - 0172-8172 SP - 303-14 ST - Body mass index and response to a multidisciplinary treatment of fibromyalgia T2 - Rheumatol Int TI - Body mass index and response to a multidisciplinary treatment of fibromyalgia VL - 35 ID - 3561 ER - TY - JOUR AB - Although the etiology of chronic pain following trauma is not well understood, numerous retrospective studies have shown that a significant proportion of chronic pain patients have a history of traumatic injury. The present analysis examines the prevalence and early predictors of chronic pain in a cohort of prospectively followed severe lower extremity trauma patients. Chronic pain was measured using the Graded Chronic Pain Scale, which measures both pain severity and pain interference with activities. Severe lower extremity trauma patients report significantly higher levels of chronic pain than the general population (p<0.001). Their levels are comparable to primary care migraine headache and back pain populations. A number of early predictors of chronic pain were identified, including: having less than a high school education (p<0.01), having less than a college education (p<0.001), low self-efficacy for return to usual major activities (p<0.01), and high levels of average alcohol consumption at baseline (p<0.05). In addition, high reported pain intensity, high levels of sleep and rest dysfunction, and elevated levels of depression and anxiety at 3 months post-discharge were also strong predictors of chronic pain at seven years (p<0.001 for all three predictors). After adjusting for early pain intensity, patients treated with narcotic medication during the first 3 months post-discharge had lower levels of chronic pain at 84 months. It is possible that for patients within these high risk categories, early referral to pain management and/or psychologic intervention may reduce the likelihood or severity of chronic pain. AD - Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA Department of Physical Medicine and Rehabilitation, Johns Hopkins University, Baltimore, MD, USA Department of Orthopaedic Surgery, Carolinas Medical Center, Charlotte, NC, USA. AN - 16781066 AU - Castillo, R. C. AU - MacKenzie, E. J. AU - Wegener, S. T. AU - Bosse, M. J. DA - Oct DO - 10.1016/j.pain.2006.04.020 DP - NLM ET - 2006/06/20 IS - 3 KW - Adult Aged Alcohol Drinking/epidemiology Amputation/psychology/*statistics & numerical data Anxiety/epidemiology Chronic Disease Depression/epidemiology Educational Status Follow-Up Studies Humans Leg Injuries/*epidemiology/surgery Limb Salvage/psychology/*statistics & numerical data Middle Aged Multivariate Analysis Narcotics/therapeutic use Pain/drug therapy/*epidemiology/psychology Predictive Value of Tests Prevalence Prospective Studies Risk Factors Self Efficacy Sleep Wake Disorders/epidemiology LA - eng N1 - 1872-6623 Castillo, Renan C MacKenzie, Ellen J Wegener, Stephen T Bosse, Michael J LEAP Study Group Journal Article United States Pain. 2006 Oct;124(3):321-329. doi: 10.1016/j.pain.2006.04.020. Epub 2006 Jun 15. PY - 2006 SN - 0304-3959 SP - 321-329 ST - Prevalence of chronic pain seven years following limb threatening lower extremity trauma T2 - Pain TI - Prevalence of chronic pain seven years following limb threatening lower extremity trauma VL - 124 ID - 3510 ER - TY - JOUR AB - Background: Abdominal pain related to irritable bowel syndrome (IBS) and functional abdominal pain (FAP) is frequent in children and can be of variable severity. Both IBS and FAP are associated with rectal hypersensitivity. We hypothesized that in children with IBS and FAP, the rectal sensory threshold for pain (RSTP) is associated with symptom severity. Paitents and Methods: A total of 47 patients (34 girls; median age, 14.2 years) with IBS (n = 29) and FAP (n = 18), according to the Rome 11 criteria, underwent a rectal barostat examination to determine their RSTR Gastrointestinal symptom severity was assessed by validated questionnaires. During the rectal barostat exam, symptoms were documented using a visual analog scale and by measuring the area coloured on a human body diagram corresponding to painful sensations. Results: The median RSTP was 16 mmHg and was similar in IBS and FAP patients. Eighty-three percent of the patients had rectal hypersensitivity (RSTP <= 30.8 mmHg, the 5th percentile of control children studied in our laboratory). Fifty-one percent and 36%, respectively, reported missing school and social activities at least once per week. Increased frequency of pain, missed days of school, missed social activities, and pain during the barostat examination were not associated with lower RSTP values in either the whole group or in the subset of children with rectal hypersensitivity. Conclusions: Rectal hypersensitivity is not proportional to the severity of symptoms in children with IBS and FAP, indicating that symptom severity is influenced by other factors in addition to visceral hypersensitivity. AN - WOS:000253551300006 AU - Castilloux, J. AU - Noble, A. AU - Faure, C. DA - Mar DO - 10.1097/MPG.0b013e31814b91e7 IS - 3 N1 - Castilloux, Julie Noble, Angela Faure, Christophe Faure, Christophe/AAD-8425-2019 Faure, Christophe/0000-0002-2998-8935 PY - 2008 SN - 0277-2116 SP - 272-278 ST - Is visceral hypersensitivity correlated with symptom severity in children with functional gastrointestinal disorders? T2 - Journal of Pediatric Gastroenterology and Nutrition TI - Is visceral hypersensitivity correlated with symptom severity in children with functional gastrointestinal disorders? UR - ://WOS:000253551300006 VL - 46 ID - 2660 ER - TY - JOUR AB - OBJECTIVE: To evaluate the frequency of anxiety and depression disorders in patients with chronic pain. METHOD: Patients receiving care at the pain clinic of the Federal University of Bahia between February 2003 and November 2006. The MINI PLUS--Mini International Neuropsychiatric Interview was used to evaluate the patients and establish psychiatric diagnoses. RESULTS: 400 patients were evaluated mean age was 45.6+/-11.37 years; 82.8% were female, 17.3% male; 48.5% were married; 55.1% were Catholics; and 40.5% had only high school education. Of these 29.9% reported intense pain and 70.8% reported suffering pain daily. The most frequent medical diagnosis was herniated disc (24.5%), and 48.5% of patients had been undergoing treatment at the pain clinic for less than 3 months. Comorbidities found were depressive episodes (42%), dysthymia (54%), social phobia (36.5%), agoraphobia (8.5%) and panic disorder (7.3%). CONCLUSION: Psychiatric comorbidities are prevalent in patients suffering chronic pain. AD - Pain Clinic, Professor Edgard Santos University Hospital, Federal University of Bahia, Salvador, BA, Brazil. marthamcastro@uol.com.br AN - 20069205 AU - Castro, M. AU - Kraychete, D. AU - Daltro, C. AU - Lopes, J. AU - Menezes, R. AU - Oliveira, I. DA - Dec DO - 10.1590/s0004-282x2009000600004 DP - NLM ET - 2010/01/14 IS - 4 KW - Anxiety Disorders/*etiology Chronic Disease Cross-Sectional Studies Depressive Disorder/*etiology Female Humans Male Middle Aged Pain/*psychology Socioeconomic Factors LA - eng N1 - 1678-4227 Castro, Martha Kraychete, Durval Daltro, Carla Lopes, Josiane Menezes, Rafael Oliveira, Irismar Journal Article Brazil Arq Neuropsiquiatr. 2009 Dec;67(4):982-5. doi: 10.1590/s0004-282x2009000600004. PY - 2009 SN - 0004-282x SP - 982-5 ST - Comorbid anxiety and depression disorders in patients with chronic pain T2 - Arq Neuropsiquiatr TI - Comorbid anxiety and depression disorders in patients with chronic pain VL - 67 ID - 3502 ER - TY - JOUR AB - Background: This study investigated the relationship between verbal aggression against school teachers and upper extremity (neck, shoulder, upper limb, and/or upper back) musculoskeletal pain. Methods: This was a cross-sectional study of 525 elementary school teachers from Jaboatao dos Guararapes, Northeast Brazil. Results: The prevalence of upper extremity musculoskeletal pain among teachers who reported verbal aggression in the past six months (67.7%) was higher than that among those who did not report verbal aggression (51.7%): (prevalence ratio = 1.21; 95% confidence interval = 1.04-1.40). The prevalence of upper extremity musculoskeletal pain was associated with verbal aggression, sex, and common mental disorders, controlled by skin color, age, monthly income, teachers' education, years working as a teacher, workload, and obesity. Furthermore, the measure of the association between verbal aggression and upper extremity musculoskeletal pain was modified by sex and common mental disorders, considered altogether. Teachers who suffered verbal aggression, of the feminine sex, and also having common mental disorders reported high prevalence (85.4%) of upper extremity musculoskeletal pain. Conclusion: The association between verbal violence in the school and complaints of upper extremity musculoskeletal pain was strong and modified by teachers' sex and common mental disorders. (C) 2020 Occupational Safety and Health Research Institute, Published by Elsevier Korea LLC. AN - WOS:000541503500010 AU - Ceballos, A. G. C. AU - Carvalho, F. M. DA - Jun DO - 10.1016/j.shaw.2020.02.003 IS - 2 N1 - Ceballos, Albanita G. C. Carvalho, Fernando M. ; Carvalho, Fernando/F-9811-2014 Ceballos, Albanita Gomes da Costa/0000-0002-8658-9981; Carvalho, Fernando/0000-0002-0969-0170 2093-7997 PY - 2020 SN - 2093-7911 SP - 187-192 ST - Verbal Aggression Against Teacher and Upper Extremity Musculoskeletal Pain T2 - Safety and Health at Work TI - Verbal Aggression Against Teacher and Upper Extremity Musculoskeletal Pain UR - ://WOS:000541503500010 VL - 11 ID - 1819 ER - TY - JOUR AB - OBJETIVES: To review the clinical, psychiatric, and social characteristics of complex regional pain syndrome in children and adolescents treated in the last 4 years at our pediatric pain clinic. MATERIAL AND METHODS: We analyzed the specialty of the initial treating physician, age, sex, initial diagnosis, pain intensity, degree of disability, fear of movement, clinical stage, history of trauma, time between onset and diagnosis, psychiatric illness, family support and behavior, chronic pain in near relatives, school grades and attendance, treatment given at the pediatric pain clinic, recurrences, and course of disease. RESULTS: The cases of 7 patients (4 female, 3 male) between the ages of 8 and 15 years were analyzed. Four had been referred by the child psychiatry department. The initial diagnosis was erroneous in all but 1 case. Pain intensity and associated disability were severe in 5 patients and 4 expressed intense fear of moving the limb. Five patients had initial stage I disease, 5 had a history of trauma, and 5 had been previously treated by immobilization of the limb and prescription of nonsteroidal anti-inflammatory drugs. The time between onset and diagnosis ranged from 2 to 18 months (mean [SD], 6.4 [3.5] months). In most cases psychiatric disease and concomitant social disability were present. Treatment prescribed at the pediatric pain clinic consisted of a combination of oral medication, psychologic and psychiatric counseling, and intensive physiotherapy for all but 2 children, who required regional nerve blocks. CONCLUSION: The clinical course was satisfactory for all but 1 patient, who developed severe disability. Complex regional pain syndrome affecting an upper limb is uncommon in children but not rare. AN - WOS:000449586700004 AU - Cebrian, J. AU - Sanchez, P. DO - 10.1016/s0034-9356(09)70358-5 IS - 3 N1 - Cebrian, J. Sanchez, P. 2340-3284 PY - 2009 SN - 0034-9356 SP - 163-169 ST - Pediatric complex regional pain syndrome affecting an upper limb: 7 cases and a brief review of the literature T2 - Revista Espanola De Anestesiologia Y Reanimacion TI - Pediatric complex regional pain syndrome affecting an upper limb: 7 cases and a brief review of the literature UR - ://WOS:000449586700004 VL - 56 ID - 2626 ER - TY - JOUR AB - Çekiç Ş, Özgür T, Karalı Y, Özkan T, Kılıç SŞ. Vedolizumab treatment in a patient with X-linked agammaglobulinemia, is it safe and efficient? Turk J Pediatr 2019; 61: 937-940. The loss of inflammatory regulation resulting from the absence of B-lymphocytes leads to a risk for autoimmune and autoinflammatory complications. There is no data on the use of Vedolizumab in patients with X-linked agammaglobulinemia (XLA) as well as children with another primary immunodeficiency (PID) diseases. A 4-year-old boy was admitted to our clinic with a history of recurrent respiratory tract infections. He was diagnosed with XLA based on extremely low immunoglobulins, very low level of B cells, genetic mutation of BTK gene, and family history. At the age of 8, he suffered from intermittent fever attacks, abdominal pain, weakness, oral aft, and weight loss. His clinical and laboratory features were consistent with inflammatory bowel disease. Histopathological examination of the biopsy material obtained from terminal ileum, colon and cecum showed Crohn`s disease. Initially, he was treated with prednisolone and infliximab. Because of the lack of response, infliximab treatment was switched to adalimumab. Terminal ileum was resected to relieve obstruction complication. Although he had been treated with adalimumab, a significant improvement was not observed. Vedolizumab (Entyvio™), a humanized monoclonal antibody α4β7 integrin-receptor antagonist, was commenced. After treatment with vedolizumab, his fever and abdominal pain attacks reduced, his total daily calorie intake increased and weight gain improved. He began to walk again and continued his school education properly. No side effects were observed in 18 months. This is the first immunocompromised child treated with vedolizumab. The symptoms of the patient receded and no side effect were seen during the treatment. AD - Divisions of Pediatric Immunology, Uludağ University Faculty of Medicine, Bursa, Turkey. Pediatric Gastroenterology, Department of Pediatrics, Uludağ University Faculty of Medicine, Bursa, Turkey. AN - 32134589 AU - Çekiç, Ş AU - Özgür, T. AU - Karalı, Y. AU - Özkan, T. AU - Kılıç, SŞ DO - 10.24953/turkjped.2019.06.016 DP - NLM ET - 2019/01/01 IS - 6 KW - Agammaglobulinaemia Tyrosine Kinase/genetics/metabolism Agammaglobulinemia/diagnosis/*drug therapy/genetics Antibodies, Monoclonal, Humanized/*therapeutic use Child, Preschool DNA/genetics DNA Mutational Analysis Gastrointestinal Agents/therapeutic use Genetic Diseases, X-Linked/diagnosis/*drug therapy/genetics Humans Magnetic Resonance Imaging Male Mutation *X linked agammaglobulinemia *adalimumab *crohn`s disease *vedolizumab LA - eng N1 - Çekiç, Şükrü Özgür, Taner Karalı, Yasin Özkan, Tanju Kılıç, Sara Şebnem Case Reports Turkey Turk J Pediatr. 2019;61(6):937-940. doi: 10.24953/turkjped.2019.06.016. PY - 2019 SN - 0041-4301 (Print) 0041-4301 SP - 937-940 ST - Vedolizumab treatment in a patient with X-linked agammaglobulinemia, is it safe and efficient? T2 - Turk J Pediatr TI - Vedolizumab treatment in a patient with X-linked agammaglobulinemia, is it safe and efficient? VL - 61 ID - 4103 ER - TY - JOUR AB - Introduction Somatic symptoms are frequently reported by children with significant impairment in functioning. Despite studies on adult populations that suggest somatic symptoms often co-occur with difficulties in identifying and describing feelings, little research has been done in childhood. This study aimed to investigate the prevalence and frequency of somatic symptoms as well as to investigate the functional impairment in children with high number of self reported somatic symptoms versus those with fewer somatic symptoms. Additionally the parental perception of their children's somatic symptoms and functioning was explored. Finally, we explored the direct and indirect effects of difficulties in identifying feelings in predicting somatic symptoms and functional disability among school-aged children. Methods 356 Italian school-aged children and their mothers participated in this study. Children (mean age = 11.43; SD = 2.41) completed the Children's Somatization Inventory (CSI-24) to assess somatic symptoms, the Functional Disability Inventory (FDI) to assess physical and psychosocial functioning and the Alexithymia Questionnaire for Children (AQC) to evaluate alexithymic features. Mothers completed the parental forms of the CSI and the FDI. Results Among children, 66.3% did not declare somatic symptoms and 33.7% reported one or more somatic symptoms in the last two weeks. A significant positive correlation emerged between children's and mothers' CSI total scores. Both children's and mothers' FDI total scores were significantly correlated with CSI scores. A significant correlation was observed between somatic symptoms and alexithymic features. Furthermore, the data showed that somatic symptoms mediated the relationship between difficulties in identifying feelings and functional impairment. Finally, it was showed that alexithymia facet of difficulty in identifying feelings contributed in large part to the prediction of the somatic symptomatology (b = 0.978, p < 0.001; R-2 = 0.164, F(5, 350) = 10.32, p < 0.001). Conclusions Findings from this study provide evidence that a higher frequency of somatic symptoms is associated with functional disabilities and alexithymic facets in school-aged children. AN - WOS:000393712500075 AU - Cerutti, R. AU - Spensieri, V. AU - Valastro, C. AU - Presaghi, F. AU - Canitano, R. AU - Guidetti, V. C7 - e0171867 DA - Feb DO - 10.1371/journal.pone.0171867 IS - 2 N1 - Cerutti, Rita Spensieri, Valentina Valastro, Carmela Presaghi, Fabio Canitano, Roberto Guidetti, Vincenzo Presaghi, Fabio/N-1590-2019 Presaghi, Fabio/0000-0001-7880-6715; SPENSIERI, VALENTINA/0000-0001-5413-3528 PY - 2017 SN - 1932-6203 ST - A comprehensive approach to understand somatic symptoms and their impact on emotional and psychosocial functioning in children T2 - Plos One TI - A comprehensive approach to understand somatic symptoms and their impact on emotional and psychosocial functioning in children UR - ://WOS:000393712500075 VL - 12 ID - 2108 ER - TY - JOUR AB - Objective Dysmenorrhea is the most important cause of chronic pelvic pain in women. Sometimes, dysmenorrhea can be severe enough, leading women to present to emergency departments. The aim of this study was to investigate factors affecting dysmenorrhea in female patients who presented to the emergency department of our hospital. Methods Female patients who presented to our emergency department with dysmenorrhea between January 2012 and January 2014 were included in the study. Patients' demographic and clinical data were filled in the Dysmenorrhea Data Form, which was designed by the researcher by screening the relevant literature. Patients' age, educational status, smoking status, age and regularity of menarche, sexual activity, and age of dysmenorrhea onset were recorded and analyzed. Results The mean age of the patients was 21.80 +/- 3.75 years. There was a significant correlation between the type of dysmenorrhea and sexual activity (p=0.001). There was a statistically significant difference between age at menarche and age of dysmenorrhea onset (p<0.001). Absenteeism was less common in patients with an age of dysmenorrhea onset of <12 years compared with the other age groups (p<0.05). Conclusions There was a significant correlation between age at menarche and age of dysmenorrhea onset. Data obtained in this study could be used in developing educational programs on dysmenorrhea for adolescents at the age of menarche. AN - WOS:000530287300017 AU - Cetin, A. C7 - e7977 DA - May DO - 10.7759/cureus.7977 IS - 5 N1 - Cetin, Ayse 2168-8184 PY - 2020 ST - Evaluation of Biological and Sociodemographic Factors Affecting Dysmenorrhea T2 - Cureus TI - Evaluation of Biological and Sociodemographic Factors Affecting Dysmenorrhea UR - ://WOS:000530287300017 VL - 12 ID - 1826 ER - TY - JOUR AB - At present, no consensus exists among clinical and academic experts regarding an appropriate placebo for randomized controlled trials (RCTs) of spinal manipulative therapy (SMT). Therefore, we investigated whether it was possible to conduct a chiropractic manual-therapy RCT with placebo. Seventy migraineurs were randomized to a single-blinded placebo-controlled clinical trial that consisted of 12 treatment sessions over 3 months. The participants were randomized to chiropractic SMT or placebo (sham manipulation). After each session, the participants were surveyed on whether they thought they had undergone active treatment ("yes" or "no") and how strongly they believed that active treatment was received (numeric rating scale 0-10). The outcome measures included the rate of successful blinding and the certitude of the participants' beliefs in both treatment groups. At each treatment session, more than 80% of the participants believed that they had undergone active treatment, regardless of group allocation. The odds ratio for believing that active treatment was received was >10 for all treatment sessions in both groups (all p < 0.001). The blinding was maintained throughout the RCT. Our results strongly demonstrate that it is possible to conduct a single-blinded manual-therapy RCT with placebo and to maintain the blinding throughout 12 treatment sessions given over 3 months. AD - 1] Head and Neck Research Group, Research Centre, Akershus University Hospital, 1478 Lørenskog, Oslo, Norway [2] Institute of Clinical Medicine, Akershus University Hospital, University of Oslo, 1474 Nordbyhagen, Oslo, Norway. 1] Institute of Clinical Medicine, Akershus University Hospital, University of Oslo, 1474 Nordbyhagen, Oslo, Norway [2] HØKH, Research Centre, Akershus University Hospital, 1478 Lørenskog, Oslo, Norway. AN - 26145718 AU - Chaibi, A. AU - Šaltytė Benth, J. AU - Bjørn Russell, M. C2 - PMC4491841 DA - Jul 6 DO - 10.1038/srep11774 DP - NLM ET - 2015/07/07 KW - Adolescent Adult Aged Female Headache Disorders/therapy Humans Male Manipulation, Chiropractic Middle Aged Musculoskeletal Manipulations Odds Ratio *Placebo Effect Treatment Outcome Validation Studies as Topic Young Adult LA - eng N1 - 2045-2322 Chaibi, Aleksander Šaltytė Benth, Jūratė Bjørn Russell, Michael Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't Sci Rep. 2015 Jul 6;5:11774. doi: 10.1038/srep11774. PY - 2015 SN - 2045-2322 SP - 11774 ST - Validation of Placebo in a Manual Therapy Randomized Controlled Trial T2 - Sci Rep TI - Validation of Placebo in a Manual Therapy Randomized Controlled Trial VL - 5 ID - 3655 ER - TY - JOUR AB - Objectives: To describe the demography, clinical characteristics, treatment, functional limitations and outcomes of patients referred to a paediatric multidisciplinary pain clinic. Design: Prospective data collection, descriptive study. Patients and setting: Tertiary referral centre pain clinic (Royal Children's Hospital, Melbourne) over two years (March 1998 - March 2000). Main outcome measures: Pain profile; functional disability (school absenteeism, sleep disturbance and inability to perform sport); treatments received; outcome. Results: 207 patients (mean age, 13.1 years; 73% females; 29% rural residents) were referred in the two years. Concomitant medical conditions were present in 106/207 (51 %) patients, the commonest being cerebral palsy or spasticity (22 patients) and malignancy (18). Complex regional pain syndrome was diagnosed in 44 patients. Functional disability due to pain included school absenteeism (95% of school attenders), sleep disruption (71% of all patients) and inability to perform sport (90% of those able to participate in sport previously). Of the 105 patients who missed five or more days of school because of pain, 93 attended school regularly after treatment. Sleep disturbance improved in 129/146 (88%) patients, and 129/147 (88%) resumed sporting activity after multidisciplinary intervention. Outcome was classified as good in 134 patients (65%), moderate in 32 (15%) and poor in 16 (8%). Conclusions: Chronic pain in children and adolescents often results in considerable functional disability. Functional improvement can be achieved using a multidisciplinary approach to pain management in children. AN - WOS:000172022700010 AU - Chalkiadis, G. A. DA - Nov DO - 10.5694/j.1326-5377.2001.tb143680.x IS - 9 N1 - Chalkiadis, GA 1326-5377 PY - 2001 SN - 0025-729X SP - 476-+ ST - Management of chronic pain in children T2 - Medical Journal of Australia TI - Management of chronic pain in children UR - ://WOS:000172022700010 VL - 175 ID - 2844 ER - TY - JOUR AB - BACKGROUND: Patients with fibromyalgia report persistent widespread pain, fatigue, and substantial functional limitations, which may lead to high health resource use (HRU) and lost productivity. Previous analyses of the U.S. population have not examined the direct and indirect costs of fibromyalgia by severity level. OBJECTIVES: To assess (a) HRU, direct and indirect costs associated with fibromyalgia in routine clinical practice in the United States using a patient-centric approach, and (b) the relationship of fibromyalgia severity level to HRU and costs. METHODS: This study recruited a nonprobability convenience sample of 203 subjects aged 18 through 65 years between August 2008 and February 2009 from 20 U.S. community-based physician offices. Subjects had a prior diagnosis of fibromyalgia by a rheumatologist, neurologist, or pain specialist; received treatment at the enrolling physician's practice for at least 3 months; experienced widespread pain for at least 3 months; and experienced pain in the previous 24 hours. Subjects completed a 106-item patient questionnaire that included 5 validated health-related quality-of-life instruments and study-specific questions about demographics; clinical history; overall health; treatment satisfaction; and impact of fibromyalgia on cognitive function, daily activities, and employment status. Subjects also self-reported hours of unpaid informal caregiver time because of inability to perform daily activities (e.g., housework, child care), out-of-pocket expenses for medical and nonmedical services, and lost productivity related to fibromyalgia for the previous 4 weeks. The 20-item Fibromyalgia Impact Questionnaire total score was used to stratify subjects into fibromyalgia severity groups (0 to less than 39 = mild, 39 to less than 59 = moderate, 59 to 100 = severe). Staff at each site recorded clinical characteristics, HRU, and medication use attributable to fibromyalgia on a paper clinical case report form (CRF) based on a 3-month retrospective medical chart review. Unit costs for 2009 were assigned to the 3-month HRU data reported on the CRF and 4-week subject-reported lost productivity. Costs were then annualized and reported in the following categories: direct medical, direct nonmedical, and indirect. Differences across severity levels were evaluated using the Kruskal-Wallis test (continuous measures) and Pearson chi-square or Fisher's exact tests (categorical measures) at the 0.05 alpha level. RESULTS: Of the 203 subjects, 21(10.3%) had mild, 49 (24.1%) had moderate, and 133 (65.5%) had severe fibromyalgia. For subjects with mild, moderate, and severe fibromyalgia, respectively, the number of fibromyalgia-related medications (3-month means: 1.8, 2.3, and 2.8, P = 0.011) and office visits to health care providers (3-month means: 2.7, 5.2, and 6.9, P < 0.001) significantly differed across severity levels. Across severity levels, total medical and nonmedical out-of-pocket costs also differed (P = 0.025). Mean [median] 3-month total direct costs (including payer costs for HRU and out-of-pocket costs for medical and nonmedical services) were $1,213 [$1,150], $1,415 [$1,215], and $2,329 [$1,760] for subjects with mild, moderate, and severe fibromyalgia, respectively (P = 0.002); and mean [median] 3-month indirect costs (including subject-reported absenteeism, unemployment, disability, and the estimated value of unpaid informal care) were $1,341 [$0], $5,139 [$1,680], and $8,285 [$7,030] (P < 0.001). Mean total indirect costs accounted for 52.5%, 78.4%, and 78.1% of mean total costs for subjects with mild, moderate, and severe fibromyalgia, respectively. CONCLUSIONS: Direct and indirect costs related to fibromyalgia are higher among subjects with worse fibromyalgia severity. Indirect costs account for a majority of fibromyalgia-related costs at all fibromyalgia severity levels. J Manag Care Pharm. 2012;18(6):415-26 Copyright (C) 2012, Academy of Managed Care Pharmacy. All rights reserved. AN - WOS:000307318600001 AU - Chandran, A. AU - Schaefer, C. AU - Ryan, K. AU - Baik, R. AU - McNett, M. AU - Zlateva, G. DA - Jul-Aug DO - 10.18553/jmcp.2012.18.6.415 IS - 6 N1 - Chandran, Arthi Schaefer, Caroline Ryan, Kellie Baik, Rebecca McNett, Michael Zlateva, Gergana Chandran, Arthi/0000-0002-5291-2103 PY - 2012 SN - 1083-4087 SP - 415-426 ST - The Comparative Economic Burden of Mild, Moderate, and Severe Fibromyalgia: Results from a Retrospective Chart Review and Cross-Sectional Survey of Working-Age U.S. Adults T2 - Journal of Managed Care Pharmacy TI - The Comparative Economic Burden of Mild, Moderate, and Severe Fibromyalgia: Results from a Retrospective Chart Review and Cross-Sectional Survey of Working-Age U.S. Adults UR - ://WOS:000307318600001 VL - 18 ID - 2423 ER - TY - JOUR AB - OBJECTIVE: To estimate the frequency of chronic joint pain after infection with chikungunya virus in a Latin American cohort. METHODS: A cross-sectional follow-up of a prospective cohort of 500 patients from the Atlántico Department, Colombia who were clinically diagnosed as having chikungunya virus during the 2014-2015 epidemic was conducted. Baseline symptoms and follow-up symptoms at 20 months were evaluated in serologically confirmed cases. RESULTS: Among the 500 patients enrolled, 485 had serologically confirmed chikungunya virus and reported joint pain status. Patients were predominantly adults (mean ± SD age 49 ± 16 years) and female, had an education level of high school or less, and were of Mestizo ethnicity. The most commonly affected joints were the small joints, including the wrists, ankles, and fingers. The initial virus symptoms lasted a median of 4 days (interquartile range [IQR] 3-8 days). Sixteen percent of the participants reported missing school or work (median 4 days [IQR 2-7 days]). After 20 months, one-fourth of the participants had persistent joint pain. A multivariable analysis indicated that significant predictors of persistent joint pain included college graduate status, initial symptoms of headache or knee pain, missed work, normal activities affected, ≥4 days of initial symptoms, and ≥4 weeks of initial joint pain. CONCLUSION: This is the first report to describe the frequency of chikungunya virus-related arthritis in the Americas after a 20-month follow-up. The high frequency of chronic disease highlights the need for the development of prevention and treatment methods. AD - The George Washington University, Washington, DC. Allied Research Society, Barranquilla, Colombia. Universidad El Bosque, Bogotá, Colombia. University of Nebraska Medical Center, Omaha. US Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland. University of California at San Diego. AN - 29266783 AU - Chang, A. Y. AU - Encinales, L. AU - Porras, A. AU - Pacheco, N. AU - Reid, S. P. AU - Martins, K. A. O. AU - Pacheco, S. AU - Bravo, E. AU - Navarno, M. AU - Rico Mendoza, A. AU - Amdur, R. AU - Kamalapathy, P. AU - Firestein, G. S. AU - Bethony, J. M. AU - Simon, G. L. C2 - PMC7928267 C6 - NIHMS921079 DA - Apr DO - 10.1002/art.40384 DP - NLM ET - 2017/12/22 IS - 4 KW - Adult Arthralgia/*epidemiology/virology Arthritis, Infectious/*epidemiology/virology Chikungunya Fever/*complications/virology *Chikungunya virus Chronic Pain/*epidemiology/virology Colombia/epidemiology Cross-Sectional Studies Female Follow-Up Studies Humans Male Middle Aged Prospective Studies LA - eng N1 - 2326-5205 Chang, Aileen Y Orcid: 0000-0001-7410-9867 Encinales, Liliana Porras, Alexandra Pacheco, Nelly Reid, St Patrick Martins, Karen A O Pacheco, Shamila Bravo, Eyda Navarno, Marianda Rico Mendoza, Alejandro Amdur, Richard Kamalapathy, Priyanka Firestein, Gary S Bethony, Jeffrey M Simon, Gary L KL2 TR001877/TR/NCATS NIH HHS/United States UL1 TR001876/TR/NCATS NIH HHS/United States Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Arthritis Rheumatol. 2018 Apr;70(4):578-584. doi: 10.1002/art.40384. Epub 2018 Mar 2. PY - 2018 SN - 2326-5191 (Print) 2326-5191 SP - 578-584 ST - Frequency of Chronic Joint Pain Following Chikungunya Virus Infection: A Colombian Cohort Study T2 - Arthritis Rheumatol TI - Frequency of Chronic Joint Pain Following Chikungunya Virus Infection: A Colombian Cohort Study VL - 70 ID - 3762 ER - TY - JOUR AB - Objective: To investigate whether the clinical history, particularly of the adolescence period, contains markers of deeply infiltrating endometriosis (DIE). Design: Cross-sectional study. Setting: Universitary tertiary referral center. Patient(s): Two hundred twenty-nine patients operated on for endometriosis. Endometriotic lesions were histologically confirmed as non-DIE (superficial peritoneal endometriosis and/or ovarian endometriomas) (n = 131) or DIE (n = 98). Intervention(s): Surgical excision of endometriotic lesions with pathological analysis of each specimens. Main Outcome Measure(s): Epidemiological data, pelvic pain scores, family history of endometriosis, absenteeism from school during menstruation, oral contraceptive (OC) pill use. Result(s): Patients with DIE had significantly more positive family history of endometriosis (odds ratio [OR] 3.2; 95% confidence interval [CI]: 1.2-8.8) and more absenteeism from school during menstruation (OR 1.7; 95% CI: 1-3). The OC pill use for treating severe primary dysmenorrhea was more frequent in patients with DIE (OR 4.5; 95% CI: 1.9-10.4). Duration of OC pill use for severe primary dysmenorrhea was longer in patients with DIE (8.4 +/- 4.7 years vs. 5.1 +/- 3.8 years). There was a higher incidence of OC pill use for severe primary dysmenorrhea before 18 years of age in patients with DIE (OR 4.2; 95% CI: 1.8-10.0). Conclusion(s): The knowledge of adolescent period history can identify markers that are associated with DIE in patients undergoing surgery for endometriosis. (Fertil Steril (R) 2011; 95: 877-81. (C) 2011 by American Society for Reproductive Medicine.) AN - WOS:000287480300008 AU - Chapron, C. AU - Lafay-Pillet, M. C. AU - Monceau, E. AU - Borghese, B. AU - Ngo, C. AU - Souza, C. AU - de Ziegler, D. DA - Mar DO - 10.1016/j.fertnstert.2010.10.027 IS - 3 N1 - Chapron, Charles Lafay-Pillet, Marie-Christine Monceau, Elise Borghese, Bruno Ngo, Charlotte Souza, Carlos de Ziegler, Dominique de Souza, Carlos Augusto Bastos/G-4872-2014; Chapron, Charles/O-8567-2017 Ngo, Charlotte/0000-0002-6225-8803 1556-5653 PY - 2011 SN - 0015-0282 SP - 877-881 ST - Questioning patients about their adolescent history can identify markers associated with deep infiltrating endometriosis T2 - Fertility and Sterility TI - Questioning patients about their adolescent history can identify markers associated with deep infiltrating endometriosis UR - ://WOS:000287480300008 VL - 95 ID - 2507 ER - TY - JOUR AB - PURPOSE: This was the open-label study to evaluate the potential benefit of Pinus radiata bark extract and vitamin C as a treatment for migraine. METHODS: Fifty outpatients with chronic migraine refractory to at least two prophylactic medications were treated with an antioxidant formulation of 1200 mg Pinus radiata bark extract and 150 mg vitamin C daily for 3 months. Patients completed migraine disability assessment (MIDAS) questionnaires at the beginning and end of the study to assess migraine impact on work, school, domestic and social activities over the three months prior to enrollment and the three month treatment period. Patients continued existing pharmacologic medications during the study. Patients who were responders were assessed for migraine impact using MIDAS questionnaires every 3 months for 12 months. RESULTS: Twenty nine patients (58%) showed improvement in MIDAS score, number of headache days and headache severity score over the 3 months of treatment. Mean MIDAS score significantly improved from 30.3 days at baseline to 14.4 days; mean number of headache days significantly reduced from 47.9 days at baseline to 25.9 days, and mean headache severity reduced from 8.1 out of 10 to 5.6 after 3 months therapy. The responders who continuously took Pinus radiata bark extract and vitamin C combination for 12 months experienced ongoing migraine relief with more than 50% reduction of frequency and severity of headaches. CONCLUSION: These data suggest that the antioxidant therapy used in this study may be beneficial in the treatment of migraine possibly reducing headache frequency and severity. AD - Department of Neurology, Kaiser Permanente Medical Center, Anaheim, CA, USA. siri.chayasirisobhon@kp.org AN - 23479241 AU - Chayasirisobhon, S. DA - Mar DP - NLM ET - 2013/03/13 IS - 1 KW - Adolescent Adult Aged Ascorbic Acid/*administration & dosage Disability Evaluation Drug Therapy, Combination Female Humans Longitudinal Studies Male Middle Aged Migraine Disorders/*prevention & control Phytotherapy/*methods Pinus/*chemistry Plant Preparations/*therapeutic use Prospective Studies Severity of Illness Index Surveys and Questionnaires Time Factors Young Adult LA - eng N1 - Chayasirisobhon, Sirichai Journal Article China (Republic : 1949- ) Acta Neurol Taiwan. 2013 Mar;22(1):13-21. PY - 2013 SN - 1028-768X (Print) 1028-768x SP - 13-21 ST - Efficacy of Pinus radiata bark extract and vitamin C combination product as a prophylactic therapy for recalcitrant migraine and long-term results T2 - Acta Neurol Taiwan TI - Efficacy of Pinus radiata bark extract and vitamin C combination product as a prophylactic therapy for recalcitrant migraine and long-term results VL - 22 ID - 3852 ER - TY - JOUR AB - OBJECTIVE: To identify the cause of an outbreak of foot pain syndrome among students from a senior high school in Foshan. METHODS: We defined a suspect case as onset of foot pain/numbness with unknown reason among students and teachers in a school of Foshan city, from February 10 to March 16, 2014. A suspect case was noticed as having both food pain and numbness. All the cases were searched through reviewing medical records in the nearby hospitals and school's clinic, also the records of absenteeism in school. Clinical information was collected from all the students, using a standardized questionnaire. Daily temperature was collected from all the students, between January 1 and March 31, 2014. A 1 : 2 individual matched case-control study was conducted to identify related risk factors on this epidemic. We interviewed all the cases and controls on their diet, physical activities and measures used for warming. RESULTS: A total of 407 case-students were identified, with an attack rate (AR) as 26.5%. The AR was 37.3% in girls, compared to 12.9% in boys. The difference was statistically significant (χ² = 115.1, P < 0.01). Boarding students had a higher AR (31.8%) than the commuting students (16.2%). The difference was statistically significant (χ² = 43.2, P < 0.01). In girls, boarding students had higher AR (46.1%) than those commuting students (18.5%). The difference was statistically significant (χ² = 61.4, P < 0.01). No statistically significant difference was found between boarding or commuting students in boys. Outdoor temperature was coming down from 23 °C on February 6 to 6 °C on February 13, but gradually rose to 23 °C on February 28. There was a positive relationship (r = 0.65, P = 0.002) noticed between daily maximum temperature and the number of cases during February 13-28. Results from this case-control study showed that factors as lacking physical activities (OR = 2.8, 95% CI: 1.5-5.6), feeling cold in bed (OR = 3.0, 95% CI: 1.3-7.0) and having experienced similar symptoms (OR = 3.4, 95% CI: 1.1-11.0) could increase the risk of this disease. CONCLUSION: This outbreak was possibly caused by the abrupt fluctuation of temperature within a short period. AD - Chancheng Center for Disease Control and Prevention of Guangdong Province, Foshan 528000, China. Xuanwu Hospital, Capital Medical University. Institute of Skin Diseases, China Academy of Medical Sciences. Peking University Sixth Hospital. Chinese Field Epidemiology Training Program, Chinese Center for Disease Control and Prevention; Institute for Communicable Disease Control and Prevention, Shijiazhuang Center for Disease Control and Prevention. National Health and Family Planning Commission. Chancheng Prefectural Experimental High School. Chinese Field Epidemiology Training Program, Chinese Center for Disease Control and Prevention; Email: cfetpzlj@126.com. Chinese Field Epidemiology Training Program, Chinese Center for Disease Control and Prevention. AN - 26564639 AU - Chen, F. AU - Shao, Z. AU - Liang, C. AU - Wang, X. AU - Yang, X. AU - Yao, G. AU - Zhao, S. AU - Wang, L. AU - Ou, Z. AU - Zhang, L. AU - Luo, H. DA - Jun DP - NLM ET - 2015/11/14 IS - 6 KW - Case-Control Studies China/epidemiology *Disease Outbreaks Female Foot Diseases/*epidemiology Humans Male Pain/*epidemiology Residence Characteristics/statistics & numerical data Risk Factors *Schools Students/*statistics & numerical data Surveys and Questionnaires Syndrome Temperature Time Factors Transportation/statistics & numerical data LA - chi N1 - Chen, Fengling Shao, Zhaoming Liang, Chaobin Wang, Xiangbo Yang, Xueyuan Yao, Guizhong Zhao, Shuqing Wang, Lili Ou, Zhongying Zhang, Lijie Luo, Huiming Journal Article China Zhonghua Liu Xing Bing Xue Za Zhi. 2015 Jun;36(6):629-33. PY - 2015 SN - 0254-6450 (Print) 0254-6450 SP - 629-33 ST - [An outbreak of foot pain syndrome among students from a senior high school in Foshan, Guangdong province, 2014] T2 - Zhonghua Liu Xing Bing Xue Za Zhi TI - [An outbreak of foot pain syndrome among students from a senior high school in Foshan, Guangdong province, 2014] VL - 36 ID - 3910 ER - TY - CHAP A2 - Stephanidis, C. AB - There is a growing concern about students' psychological health at school with mounting pressure as students approach middle school or college age. In light of the fact that the current means of psychological intervention are basically manual intervention, this research explored the possibility of using technology to assist psychological intervention. An emotion management system is thus implemented to provide facial emotion cognitive service and video diary function. In addition to the advantage of keeping a normal diary, students benefit by regulating their emotion when they are recording videos. Teachers can keep track of students' emotion states so that they can provide corresponding psychological supports when students showed signs of mental disorders. We performed a small-scale pilot study at a local school with satisfying results. AN - WOS:000553811700051 AU - Chen, J. AU - Qiu, X. Y. AU - Winoto, P. DO - 10.1007/978-3-319-92279-9_51 N1 - Chen, Jie Qiu, Xiaoyang Winoto, Pinata 20th International Conference on Human-Computer Interaction (HCI International) Jul 15-20, 2018 Las Vegas, NV 1865-0929 PY - 2018 SN - 978-3-319-92279-9; 978-3-319-92278-2 SP - 380-386 ST - An Emotion Management System via Face Tracking, Data Management, and Visualization T2 - Hci International 2018 - Posters' Extended Abstracts, Pt Ii T3 - Communications in Computer and Information Science TI - An Emotion Management System via Face Tracking, Data Management, and Visualization UR - ://WOS:000553811700051 VL - 851 ID - 2057 ER - TY - JOUR AB - Experimental ooplasmic transplantation from donor to recipient oocyte took place between 1996 and 2001 at Saint Barnabas Medical Center, USA. Indication for 33 patients was repeated implantation failure. Thirteen couples had 17 babies. One patient delivered twins from mixed ooplasmic and donor egg embryos. A limited survey-based follow-up study on the children is reported: 12 out of 13 parents completed a questionnaire on pregnancy, birth, health, academic performance and disclosure. Parents of a quadruplet did not participate. Prenatal development and delivery were uneventful. School grades ranged from good to excellent. Children were of good health. Body mass index (BMI) was normal in 12 out of 13 children. One child had chronic migraine headaches, two mild asthma, three minor vision and three minor skin problems. One boy from a boy/girl twin was diagnosed with borderline pervasive developmental disorder - not otherwise specified at age 18 months, but with no later symptoms. One couple disclosed the use of egg donor to their child. One reported intention to disclose; six were undecided and four reported they would not disclose. This limited follow-up strategy presents a high risk of bias. Parents may not assent to standardized clinical analysis owing to lack of disclosure to their children. (C) 2016 The Authors. Published by Elsevier Ltd on behalf of Reproductive Healthcare Ltd. AN - WOS:000393169500009 AU - Chen, S. H. AU - Pascale, C. AU - Jackson, M. AU - Szvetecz, M. A. AU - Cohen, J. DA - Dec DO - 10.1016/j.rbmo.2016.10.003 IS - 6 N1 - Chen, Serena H. Pascale, Claudia Jackson, Maria Szvetecz, Mary Ann Cohen, Jacques 1472-6491 PY - 2016 SN - 1472-6483 SP - 737-744 ST - A limited survey-based uncontrolled follow-up study of children born after ooplasmic transplantation in a single centre T2 - Reproductive Biomedicine Online TI - A limited survey-based uncontrolled follow-up study of children born after ooplasmic transplantation in a single centre UR - ://WOS:000393169500009 VL - 33 ID - 2127 ER - TY - JOUR AB - This study used data from Waves I and II of the Taiwan Educational Panel Survey (TEPS) to explore the potential short-term and long-term effects of parental illness and health condition on children's behavioral and educational functioning. A sample of 11,018 junior high school students and their parents and teachers in Taiwan were included in this present study. The results supported previous work that parental illness may place children at slight risk for poor psychosocial adjustment and behavioral problems. Parental illness was associated with lower adaptive skills and more behavioral problems in children. Children of ill parents showed resilience in their educational functioning in the event of parental illness as children's academic achievement and learning skills were not related to parental illness/health condition. AN - WOS:000334291100006 AU - Chen, Y. C. DA - May DO - 10.1177/0193945913509899 IS - 5 N1 - Chen, Yung-Chi Chen, Cliff Yung-Chi/K-4115-2016 Chen, Cliff Yung-Chi/0000-0001-8659-5305 1552-8456 PY - 2014 SN - 0193-9459 SP - 664-684 ST - Exploration of the Short-Term and Long-Term Effects of Parental Illness on Children's Educational and Behavioral Functioning Using a Large Taiwanese Sample T2 - Western Journal of Nursing Research TI - Exploration of the Short-Term and Long-Term Effects of Parental Illness on Children's Educational and Behavioral Functioning Using a Large Taiwanese Sample UR - ://WOS:000334291100006 VL - 36 ID - 2309 ER - TY - JOUR AB - This study tested a theoretical relationship between trauma exposure, youth coping strategies and peer, family and community level factors on psychological distress and well-being among 399 trauma-affected youth in the Democratic Republic of Congo. Structural equation modeling (SEM) was used to analyze paths and to assess differences in relationships by gender. Psychological distress was measured by self-reports of internalizing problems (depression and anxiety), externalizing problems (aggression and behavioral problems) and somatic complaints (pain without medical cause). Self-reports of happiness, hope and self-esteem were measures of well-being. Findings from this study suggest gender differences in how individual coping strategies and external factors explain mental health resilience in trauma-affected youth. Problem-focused coping strategies were associated with higher psychological distress in both boys and girls. Use of avoidance was associated with better well-being in girls and boys and use of faith-based coping strategies was associated with better well-being in boys. Use of both problem-focused and emotion-focused coping strategies (coping flexibility) resulted in lower psychological distress in boys and girls. The home environment including closeness to family, caregiver post traumatic stress disorder and violence in the home was associated with psychological distress and well-being. Having close peer relationships, village safety and enrollment in school benefited well-being. Results from these SEM of resilience suggest that interventions should (1) work to build the coping repertoire of youth, (2) support reduction in psychological distress through improved family relationships and caregiver mental health and (3) target improved well-being through support of positive peer and community relationships and school enrollment. AN - WOS:000408063300011 AU - Cherewick, M. AU - Tol, W. AU - Burnham, G. AU - Doocy, S. AU - Glass, N. DO - 10.1080/21642850.2016.1228458 IS - 1 N1 - Cherewick, Megan Tol, Wietse Burnham, Gilbert Doocy, Shannon Glass, Nancy PY - 2016 SN - 2164-2850 SP - 155-174 ST - A structural equation model of conflict-affected youth coping and resilience T2 - Health Psychology and Behavioral Medicine TI - A structural equation model of conflict-affected youth coping and resilience UR - ://WOS:000408063300011 VL - 4 ID - 2189 ER - TY - JOUR AB - Background. Tooth decay is the most common paediatric disease and there is a serious paediatric tooth decay epidemic in Alaska Native communities. When untreated, tooth decay can lead to pain, infection, systemic health problems, hospitalisations and in rare cases death, as well as school absenteeism, poor grades and low quality-of-life. The extent to which population-based oral health interventions have been conducted in Alaska Native paediatric populations is unknown. Objective. To conduct a systematic review of oral health interventions aimed at Alaska Native children below age 18 and to present a case study and conceptual model on multilevel intervention strategies aimed at reducing sugar-sweetened beverage (SSB) intake among Alaska Native children. Design. Based on the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) Statement, the terms "Alaska Native", "children" and "oral health" were used to search Medline, Embase, Web of Science, GoogleScholar and health foundation websites (1970-2012) for relevant clinical trials and evaluation studies. Results. Eighty-five studies were found in Medline, Embase and Web of Science databases and there were 663 hits in GoogleScholar. A total of 9 publications were included in the qualitative review. These publications describe 3 interventions that focused on: reducing paediatric tooth decay by educating families and communities; providing dental chemotherapeutics to pregnant women; and training mid-level dental care providers. While these approaches have the potential to improve the oral health of Alaska Native children, there are unique challenges regarding intervention acceptability, reach and sustainability. A case study and conceptual model are presented on multilevel strategies to reduce SSB intake among Alaska Native children. Conclusions. Few oral health interventions have been tested within Alaska Native communities. Community-centred multilevel interventions are promising approaches to improve the oral and systemic health of Alaska Native children. Future investigators should evaluate the feasibility of implementing multilevel interventions and policies within Alaska Native communities as a way to reduce children's health disparities. AN - WOS:000325721900222 AU - Chi, D. L. C7 - 21066 DO - 10.3402/ijch.v72i0.21066 N1 - Chi, Donald L. 2242-3982 1 PY - 2013 SN - 1239-9736 SP - 633-645 ST - Reducing Alaska Native paediatric oral health disparities: a systematic review of oral health interventions and a case study on multilevel strategies to reduce sugar-sweetened beverage intake T2 - International Journal of Circumpolar Health TI - Reducing Alaska Native paediatric oral health disparities: a systematic review of oral health interventions and a case study on multilevel strategies to reduce sugar-sweetened beverage intake UR - ://WOS:000325721900222 VL - 72 ID - 2392 ER - TY - JOUR AB - Purpose. The purpose of this study was to examine the influencing factors of postoperative pain among children undergoing elective surgery. Design and Methods. A survey was conducted in 2011 with a convenience sample of 66 children, 6 to 14 years old, in a tertiary hospital in Singapore. Results. Children experienced moderate preoperative anxiety and postoperative pain. Gender, preoperative anxiety, and negative emotional behaviors were significant influencing factors for postoperative pain. Boys reported less postoperative pain than girls. Practice Implications. Effective strategies for assessing and managing children's preoperative anxiety are needed to achieve an optimal postoperative pain management outcome. AN - WOS:000321296100009 AU - Chieng, Y. J. S. AU - Chan, W. C. S. AU - Liam, J. L. W. AU - Klainin-Yobas, P. AU - Wang, W. R. AU - He, H. G. DA - Jul DO - 10.1111/jspn.12030 IS - 3 N1 - Chieng, Ying Jia Shermin Chan, Wai Chi Sally Liam, Joanne Li Wee Klainin-Yobas, Piyanee Wang, Wenru He, Hong-Gu Wang, Wenru/N-1523-2019; Chan, Sally Wai Chi/ABB-8520-2020 Chan, Sally Wai Chi/0000-0001-5484-4645; Wang, Wenru/0000-0002-0265-8215 PY - 2013 SN - 1539-0136 SP - 243-252 ST - Exploring influencing factors of postoperative pain in school-age children undergoing elective surgery T2 - Journal for Specialists in Pediatric Nursing TI - Exploring influencing factors of postoperative pain in school-age children undergoing elective surgery UR - ://WOS:000321296100009 VL - 18 ID - 2362 ER - TY - JOUR AB - Children aged 6 to 11 who have been injured in a traffic accident were observed over a one year period, in parallel with a control group of children. More than one-third of the injured children had been hospitalized (for periods ranging anywhere between 1 and 47 days). One year later, one injured child out of ten was still suffering from pain, and/or still being treated for injuries resulting from the accident. Many other factors were linked to the initial overall level of severity of the injuries, contrary to that of pain, such as the rate and duration of hospitalization, the duration of care provided, the number of medical consultations, and absenteeism from school. Children who had been injured in a road traffic accident were found to be more anxious and nervous, in general, as well as having a high prevalence of sleeping disorders in comparison to the children in the control group. AD - Unité Mixte de Recherche (Inrets-Université Claude Bernard Lyon1-InVS) Epidémiologique et de Surveillance Transport Travail Environnement, Inrets Institut national de recherche sur les transports et leur sécurité, Bron. AN - 16676711 AU - Chiron, M. AU - Charnay, P. AU - Martin, J. L. AU - Vergnes, I. DA - Mar DO - 10.3917/spub.061.0023 DP - NLM ET - 2006/05/09 IS - 1 KW - *Accidents, Traffic Age Factors Anxiety/etiology Bicycling/injuries Child Female Follow-Up Studies France Hospitalization Humans Length of Stay Male Mental Disorders/*etiology Pain/etiology Pain Management Personality Risk Factors Sex Factors Sleep Wake Disorders/*etiology Socioeconomic Factors Surveys and Questionnaires Time Factors Wounds and Injuries/*complications/psychology/therapy LA - fre N1 - Chiron, M Charnay, P Martin, J L Vergnes, I Comparative Study English Abstract Journal Article France Sante Publique. 2006 Mar;18(1):23-39. doi: 10.3917/spub.061.0023. OP - Consequénces des accidents de la circulation chez les enfants: suivi pendant un an dans le département du Rhône. PY - 2006 SN - 0995-3914 (Print) 0995-3914 SP - 23-39 ST - [Consequences for children involved in a road traffic accident: one year of observation and follow-up in the Rhone county] T2 - Sante Publique TI - [Consequences for children involved in a road traffic accident: one year of observation and follow-up in the Rhone county] VL - 18 ID - 3865 ER - TY - JOUR AB - OBJECTIVE: Recurrent abdominal pain (RAP) of childhood is a common problem encountered by clinicians. The aim of this study was to systematically review published literature about the prevalence, incidence, natural history, and co-morbid conditions of childhood RAP in western countries. METHODS: A computer-assisted search of MEDLINE, EMBASE, and Current Contents/Science Edition databases was performed. Study selection criteria included: (1) United States and European population and school-based samples of children; (2) diagnostic criteria of RAP; and (3) published in full manuscript form in English. Data were extracted, tabulated, and presented in descriptive form. RESULT: The prevalence of RAP ranged from 0.3 to 19% (median 8.4; IQR 2.3-14.7). Published studies in children demonstrate a higher prevalence of RAP in females, with the highest prevalence of symptoms between 4 and 6 yr and early adolescence. Identified studies demonstrated associations between RAP and the child's familial and socioeconomic environment. In addition, childhood RAP was reported to be associated with psychological co-morbidity in childhood and adulthood. Population/school-based studies have not, however, established the incidence of this disorder, what features predict long-standing symptoms, or whether RAP is a risk factor for adult functional bowel disorders. CONCLUSION: RAP is a common complaint of childhood with associated familial, psychological, and co-morbid conditions. Epidemiologic studies of RAP in children may offer information on the evolution of functional bowel disorders through the lifespan. AD - Motility Unit, Division of Gastroenterology and Nutrition, Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. AN - 16086724 AU - Chitkara, D. K. AU - Rawat, D. J. AU - Talley, N. J. DA - Aug DO - 10.1111/j.1572-0241.2005.41893.x DP - NLM ET - 2005/08/10 IS - 8 KW - Abdominal Pain/*epidemiology/etiology Child Chronic Disease Europe/epidemiology Humans Incidence Prevalence Recurrence United States/epidemiology LA - eng N1 - Chitkara, Denesh K Rawat, David J Talley, Nicholas J Journal Article Research Support, Non-U.S. Gov't Review Systematic Review United States Am J Gastroenterol. 2005 Aug;100(8):1868-75. doi: 10.1111/j.1572-0241.2005.41893.x. PY - 2005 SN - 0002-9270 (Print) 0002-9270 SP - 1868-75 ST - The epidemiology of childhood recurrent abdominal pain in Western countries: a systematic review T2 - Am J Gastroenterol TI - The epidemiology of childhood recurrent abdominal pain in Western countries: a systematic review VL - 100 ID - 3189 ER - TY - JOUR AB - BACKGROUND: Until recently, non-specific low back pain (NSLBP) in adolescents was considered a rare phenomenon unlike in adults. The last two decades has shown an increasing amount of research highlighting the prevalence in this age group. Recent studies estimate lifetime prevalence at 7%-80%, point prevalence at 10%-15%, and prevalence of recurrent NSLBP at 13%-36%. In Zimbabwe, there is dearth of literature on the magnitude of the problem in adolescents. Therefore, the aims of the study were to determine the prevalence (lifetime, point, recurrent) and the nature of recurrent NSLBP reported by adolescents in secondary schools. METHODS: A cross-sectional study was conducted using a questionnaire. A cluster sample of 544 adolescents (age 13-19 years) randomly derived from government schools participated in the study. Lifetime prevalence, point prevalence and prevalence of recurrent NSLBP were presented as percentages of the total population. Exact 95% confidence intervals were given. Chi-square test was used to evaluate the effect of gender and age on prevalence. RESULTS: The students' response rate was 97.8%. The lifetime prevalence was 42.9% [95% confidence interval = 40.8-44.6] with no significant difference between sexes [χ2 (1) =0.006, p=0.94]. However, NSLBP peaked earlier in female students (13.9 years) than in male students (15 years) [t (226) = 4.21, p<0.001]. About 10% of the adolescents reported having an episode of NSLBP on the day of the survey. However, female students (14.2%) were more affected on the day [χ2 (1) =11.2, p<0.001]. Twenty-nine percent of the adolescents experienced recurrent NSLBP with 78% experiencing at least three episodes in the last 12 months. On average, recurrent NSLBP reported was mild in intensity (4.8 ± 1.9) on the visual analogue scale (VAS) and short in duration. Recurrent NSLBP was associated with sciatica in 20.9% of adolescents. CONCLUSIONS: NSLBP is a common occurrence among Zimbabwean adolescents in secondary schools. It increases with chronological age and is recurrent in the minority of adolescents. Although much of the symptomatology may be considered benign, the existence of recurrent NSLBP in adolescents before their work-life begins should be a concern to health professionals, teachers and parents. AD - Department of Rehabilitation, University of Zimbabwe, College of Health Sciences, Harare, Zimbabwe. matthewchiwaridzo@yahoo.co.uk. AN - 25406690 AU - Chiwaridzo, M. AU - Naidoo, N. C2 - PMC4246475 DA - Nov 19 DO - 10.1186/1471-2474-15-381 DP - NLM ET - 2014/11/20 KW - Adolescent Cross-Sectional Studies Female Humans Low Back Pain/*diagnosis/*epidemiology Male *Pain Measurement/methods Prevalence Recurrence Young Adult Zimbabwe/epidemiology LA - eng N1 - 1471-2474 Chiwaridzo, Matthew Naidoo, Nirmala Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't BMC Musculoskelet Disord. 2014 Nov 19;15:381. doi: 10.1186/1471-2474-15-381. PY - 2014 SN - 1471-2474 SP - 381 ST - Prevalence and associated characteristics of recurrent non-specific low back pain in Zimbabwean adolescents: a cross-sectional study T2 - BMC Musculoskelet Disord TI - Prevalence and associated characteristics of recurrent non-specific low back pain in Zimbabwean adolescents: a cross-sectional study VL - 15 ID - 3565 ER - TY - JOUR AB - PURPOSE: The purpose of the study was to investigate the consequences of recurrent non-specific low back pain in Zimbabwean adolescents. Recurrent non-specific low back pain is a common cause of adult disability in low-income countries. However, its impact in adolescents has been a matter of debate in the literature. METHODS: A survey was conducted using a cluster sample of 544 school children between the ages of 13 and 19 years. The school children were randomly selected from government-administered secondary schools in Harare, Zimbabwe. RESULTS: Parental and students' response rate were 90.3 and 97.8 %, respectively. Almost a third (28.8 %) of school children reported recurrent symptoms (CI 27.8-31.6). However, the majority (84 %) of these cases were unknown to parents. Twenty-seven percent reported having sought medical treatment. On the nine-item Hanover Low Back Pain Disability Questionnaire, 71.2 % of school children had at least one activity of daily living compromised by recurrent NSLBP, especially sports participation. However, severe disability was reported in 28 % of the adolescents. Health-care seeking behaviour was not associated with the level of disability [χ (2)(1) = 0.36, p = 0.55]. CONCLUSION: Although most parents are unaware, recurrent NSLBP is common in Zimbabwean school children. However, treatment is rarely sought for the symptoms. A preponderance of adolescents with recurrent NSLBP experiences some degree of functional consequences, although severe disability is rare. There is need to raise awareness of the condition in schools and to parents. Spinal health educational programmes may need to be implemented to avert the functional consequences. Further studies are needed in the future to investigate the coping strategies for pain in adolescents. AD - Department of Rehabilitation, College of Health Sciences, University of Zimbabwe, Avondale, P.O Box A178, Harare, Zimbabwe. CHWMAT001@myuct.ac.za. Department of Health and Rehabilitation Sciences, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory, Cape Town, South Africa. niri.naidoo@uct.ac.za. AN - 26148568 AU - Chiwaridzo, M. AU - Naidoo, N. DA - Feb DO - 10.1007/s00586-015-4105-9 DP - NLM ET - 2015/07/08 IS - 2 KW - Activities of Daily Living Adolescent Age Distribution Cross-Sectional Studies Disability Evaluation Female Health Surveys Humans Low Back Pain/*diagnosis/epidemiology/physiopathology/rehabilitation Male Pain Measurement/methods Patient Acceptance of Health Care/*statistics & numerical data Prevalence Recurrence Young Adult Zimbabwe/epidemiology Adolescents Functional consequences Hanover Low Back Pain Disability Questionnaire Health-care seeking behaviour Recurrent non-specific low back pain LA - eng N1 - 1432-0932 Chiwaridzo, Matthew Naidoo, Nirmala Journal Article Germany Eur Spine J. 2016 Feb;25(2):643-50. doi: 10.1007/s00586-015-4105-9. Epub 2015 Jul 7. PY - 2016 SN - 0940-6719 SP - 643-50 ST - Functional consequences and health-care seeking behaviour for recurrent non-specific low back pain in Zimbabwean adolescents: a cross-sectional study T2 - Eur Spine J TI - Functional consequences and health-care seeking behaviour for recurrent non-specific low back pain in Zimbabwean adolescents: a cross-sectional study VL - 25 ID - 3616 ER - TY - JOUR AB - Age at menarche and menstrual symptoms were recorded in a sample of Thai schoolgirls in Bangkok. Using a random sampling proportional to size from this target population, structured questionnaires were offered to a sample of 15998 girls of grades 4-12. Fifty-six per cent of the study population was menarcheal during the time of study. Average mean ages by recalling age at menarche and by probit analysis were 12.51 +/- 1.17 and 12.35 +/- 1.41 years, respectively. The onset of menstruation occurred most frequently in April and October. Abdominal pain was the most common symptom during the menstrual period. Acne, malaise and back pain were other common complaints. AN - WOS:A1997XU50900005 AU - Chompootaweep, S. AU - Tankeyoon, M. AU - Poomsuwan, P. AU - Yamarat, K. AU - Dusitsin, N. DA - Sep-Oct DO - 10.1080/03014469700005192 IS - 5 N1 - Chompootaweep, S Tankeyoon, M Poomsuwan, P Yamarat, K Dusitsin, N PY - 1997 SN - 0301-4460 SP - 427-433 ST - Age at menarche in Thai girls T2 - Annals of Human Biology TI - Age at menarche in Thai girls UR - ://WOS:A1997XU50900005 VL - 24 ID - 2904 ER - TY - JOUR AB - BACKGROUND: The number of fluctuations of skin conductance per second (NFSC) has been shown to correlate with induced pain and self-report pain scales. This study aimed to evaluate the validity and feasibility of NFSC as an objective measurement of nociception intensity in school-aged children after surgery. METHODS: After approval by the research ethics board and obtaining consent, 100 subjects participated in this prospective observational study. Preoperatively, NFSC was measured for 60 s at rest and during response to a self-report pain scale (numeric rating scale [NRS], Faces Pain Scale-Revised) and anxiety scoring (NRS). Postoperative measurements were repeated every 10 min for 30 min or until NRS pain score was or= 7) with 56.3% sensitivity (95% CI = 37.7-73.6%) and 78.4% specificity (95% CI = 71.7-84.1%). The area under receiver operator characteristic curve for NFSC was 69.1%. CONCLUSIONS: NFSC measurement is feasible in a perioperative setting but was not specific for postoperative pain intensity and was unable to identify analgesia requirements when compared with self-report measures. AU - Choo, Eugene K. AU - Magruder, William AU - Montgomery, Carolyne J. AU - Lim, Joanne AU - Brant, Rollin AU - Ansermino, J. Mark DA - 2010/07// DO - 10.1097/ALN.0b013e3181de6ce9 DP - PubMed IS - 1 J2 - Anesthesiology KW - Adolescent Area Under Curve Child Feasibility Studies Female Galvanic Skin Response Humans Male Pain Measurement Pain, Postoperative Prospective Studies Reproducibility of Results ROC Curve Self Disclosure Sensitivity and Specificity Severity of Illness Index LA - eng PY - 2010 SN - 1528-1175 SP - 175-182 ST - Skin conductance fluctuations correlate poorly with postoperative self-report pain measures in school-aged children T2 - Anesthesiology TI - Skin conductance fluctuations correlate poorly with postoperative self-report pain measures in school-aged children UR - http://www.ncbi.nlm.nih.gov/pubmed/20526184 VL - 113 ID - 107 ER - TY - BOOK A2 - McClain, B. C. A2 - Suresh, S. AN - WOS:000291622000003 AU - Chorney, J. M. AU - Crofton, K. AU - McClain, B. C. DO - 10.1007/978-1-4419-0350-1_3 N1 - Chorney, Jill MacLaren Crofton, Kathryn McClain, Brenda C. PY - 2011 SN - 978-1-4419-0349-5 SP - 27-44 ST - Theories on Common Adolescent Pain Syndromes T2 - Handbook of Pediatric Chronic Pain: Current Science and Integrative Practice TI - Theories on Common Adolescent Pain Syndromes UR - ://WOS:000291622000003 ID - 2514 ER - TY - JOUR AB - Background: Nearly 20% of children and adolescents have pain with disability 1 year after surgery, and they experience poor sleep, school absence, and decreased activities. Negative clinical, psychological, and developmental effects include greater pain medication use, longer recovery, and fear of future medical care. Research has found psychological and family influences (i.e., child and parental anxiety) on pediatric chronic postsurgical pain (CPSP), but a better understanding of the role of perioperative anxiety and its related states in predicting pediatric postsurgical pain is needed. The poor understanding of the causes of child CPSP can lead to misdiagnosis and inadequate treatment, with significant short- and long-term effects. Objectives: The aim of this review was to summarize the literature on children's perioperative anxiety and parental anxiety in relation to acute postsurgical pain, CPSP, and pain trajectories. We also examined other related psychological factors (i.e., anxiety sensitivity, catastrophizing, pain anxiety, and fear of pain) in relation to pediatric acute and chronic postsurgical pain. Lastly, we discuss the interventions that may be effective in reducing children's and parents' preoperative anxiety. Conclusions: Our findings may improve the understanding of the causes of CPSP and highlight the gaps in research and need for further study. AN - WOS:000605584200005 AU - Chow, C. H. T. AU - Schmidt, L. A. AU - Buckley, D. N. DA - Dec DO - 10.1080/24740527.2020.1847600 IS - 4 N1 - Chow, Cheryl H. T. Schmidt, Louis A. Buckley, D. Norman Si PY - 2020 SN - 2474-0527 SP - 26-36 ST - The role of anxiety and related states in pediatric postsurgical pain T2 - Canadian Journal of Pain-Revue Canadienne De La Douleur TI - The role of anxiety and related states in pediatric postsurgical pain UR - ://WOS:000605584200005 VL - 4 ID - 1778 ER - TY - JOUR AB - Objectives: The aim of the present study was to determine whether concomitant gastroparesis and biliary dyskinesia (BD) occur in children, and if so, to determine whether concomitant gastroparesis affects clinical outcome in children with BD. Methods: We conducted a retrospective chart review of children with BD (ejection fraction <35% on cholescintigraphy, with no other metabolic or structural cause) who completed a solid-phase gastric emptying scintigraphy scan within 12 months of abnormal cholescintigraphy. Children were classified into 1 of 4 clinical outcome groups (excellent, good, fair, poor). Results: Thirty-five children with a mean follow-up time of 23.1 +/- 17.3 (standard deviation) months were included. Twenty (57%) children were identified as having concomitant gastroparesis (GP) with BD. Children with concomitant GP were more likely to have a poor clinical outcome compared with those with BD alone (P < 0.005). In children undergoing cholecystectomy, those with concomitant GP were more likely to have a fair or poor clinical outcome compared with those with BD alone (P < 0.01). Factors predicting a more favorable clinical outcome were having BD alone and not having limitations in activity (eg, school absences) at the time of presentation. Conclusions: Concomitant GP may occur in children with functional gallbladder disorders. Concomitant GP may negatively affect clinical outcome in children with BD. AN - WOS:000304115900015 AU - Chumpitazi, B. P. AU - Malowitz, S. M. AU - Moore, W. AU - Gopalakrishna, G. S. AU - Shulman, R. J. DA - Jun DO - 10.1097/MPG.0b013e3182455cf9 IS - 6 N1 - Chumpitazi, Bruno P. Malowitz, Stanton M. Moore, Warren Gopalakrishna, G. S. Shulman, Robert J. 1536-4801 PY - 2012 SN - 0277-2116 SP - 776-779 ST - Concomitant Gastroparesis Negatively Affects Children With Functional Gallbladder Disease T2 - Journal of Pediatric Gastroenterology and Nutrition TI - Concomitant Gastroparesis Negatively Affects Children With Functional Gallbladder Disease UR - ://WOS:000304115900015 VL - 54 ID - 2434 ER - TY - JOUR AB - BACKGROUND: Professional American-style football players are among the largest athletes across contemporary sporting disciplines. Weight gain during football participation is common, but the health implications of this early-life weight gain remain incompletely understood. We sought to define weight trajectories of former professional American-style football athletes and to establish their relationship with 5 common health afflictions (cardiovascular disease, cardiometabolic disease, neurocognitive impairment, sleep apnea, and chronic pain). METHODS: A health survey was distributed to former National Football League (NFL) players. Former players reported body weight at 4 time points (high school, college, professional, and time of survey response) as well as maximal retirement weight. Logistic regression was used to assess associations between weight gain during football participation and health affliction. RESULTS: In this cohort of former NFL players (n = 3,506, age 53 +/- 14 years), mean weight increase from high school to time of survey response was 40 +/- 36 pounds, with the majority of weight gain occurring during periods of football participation (high-school-to-college and college-to-professional). The prevalence of health afflictions ranged from 9% (cardiovascular disease) to 28% (chronic pain). Weight gain during football participation was independently associated with risk of multiple later-life health afflictions in models adjusted for football exposure, lifestyle variables, and post-career weight gain. CONCLUSIONS: Early-life weight gain among American-style football athletes is common and is associated with risk of adverse health profiles during later-life. These findings establish football-associated weight gain as a key predictor of post-career health and raise important questions about the central role of targeted weight gain in this population. (C) 2018 Elsevier Inc. All rights reserved. AN - WOS:000451731500028 AU - Churchill, T. W. AU - Krishnan, S. AU - Weisskopf, M. AU - Yates, B. A. AU - Speizer, F. E. AU - Kim, J. H. AU - Nadler, L. E. AU - Pascual-Leone, A. AU - Zafonte, R. AU - Baggish, A. L. DA - Dec DO - 10.1016/j.amjmed.2018.07.042 IS - 12 N1 - Churchill, Timothy W. Krishnan, Supriya Weisskopf, Marc Yates, Brandon A. Speizer, Frank E. Kim, Jonathan H. Nadler, Lee E. Pascual-Leone, Alvaro Zafonte, Ross Baggish, Aaron L. Pascual-Leone, Alvaro/AAC-5101-2019 Pascual-Leone, Alvaro/0000-0001-8975-0382 1555-7162 PY - 2018 SN - 0002-9343 SP - 1491-1498 ST - Weight Gain and Health Affliction Among Former National Football League Players T2 - American Journal of Medicine TI - Weight Gain and Health Affliction Among Former National Football League Players UR - ://WOS:000451731500028 VL - 131 ID - 1981 ER - TY - JOUR AB - Interactive sonification is an effective tool used to guide individuals when practicing movements. Little research has shown the use of interactive sonification in supporting motor therapeutic interventions for children with autism who exhibit motor impairments. The goal of this research is to study if children with autism understand the use of interactive sonification during motor therapeutic interventions, its potential impact of interactive sonification in the development of motor skills in children with autism, and the feasibility of using it in specialized schools for children with autism. We conducted two deployment studies in Mexico using Go-with-the-Flow, a framework to sonify movements previously developed for chronic pain rehabilitation. In the first study, six children with autism were asked to perform the forward reach and lateral upper-limb exercises while listening to three different sound structures (i.e., one discrete and two continuous sounds). Results showed that children with autism exhibit awareness about the sonification of their movements and engage with the sonification. We then adapted the sonifications based on the results of the first study, for motor therapy of children with autism. In the next study, nine children with autism were asked to perform upper-limb lateral, cross-lateral, and push movements while listening to five different sound structures (i.e., three discrete and two continues) designed to sonify the movements. Results showed that discrete sound structures engage the children in the performance of upper-limb movements and increase their ability to perform the movements correctly. We finally propose design considerations that could guide the design of projects related to interactive sonification AN - WOS:000593001200001 AU - Cibrian, F. L. AU - Ley-Flores, J. AU - Newbold, J. W. AU - Singh, A. AU - Bianchi-Berthouze, N. AU - Tentori, M. DA - Apr DO - 10.1007/s00779-020-01479-z IS - 2 N1 - Cibrian, Franceli L. Ley-Flores, Judith Newbold, Joseph W. Singh, Aneesha Bianchi-Berthouze, Nadia Tentori, Monica Ley Flores, Judith Guadalupe/0000-0003-0168-7601; Newbold, Joseph/0000-0002-0198-3198 1617-4917 Si PY - 2021 SN - 1617-4909 SP - 391-410 ST - Interactive sonification to assist children with autism during motor therapeutic interventions T2 - Personal and Ubiquitous Computing TI - Interactive sonification to assist children with autism during motor therapeutic interventions UR - ://WOS:000593001200001 VL - 25 ID - 1782 ER - TY - JOUR AB - OBJECTIVE: To describe the use of complementary and alternative medicine (CAM) in pediatric functional abdominal pain disorders at a large Midwestern pediatric gastroenterology center. STUDY DESIGN: A survey of patients attending a follow-up visit for functional abdominal pain disorders was completed. Data were collected on demographics, quality of life, use of conventional therapies, patient's opinions, and perception of provider's knowledge of CAM. RESULTS: Of 100 respondents (mean age, 13.3 ± 3.5 years), 47 (60% female) had irritable bowel syndrome, 29 (83% female) had functional dyspepsia, 18 (67% female) had functional abdominal pain, and 6 (83% female) had abdominal migraine (Rome III criteria). Ninety-six percent reported using at least 1 CAM modality. Dietary changes were undertaken by 69%. Multivitamins and probiotics were the most common supplements used by 48% and 33% of respondents, respectively. One-quarter had seen a psychologist. Children with self-reported severe disease were more likely to use exercise (P < .05); those with active symptoms (P < .01) or in a high-income group (P < .05) were more likely to make dietary changes; and those without private insurance (P < .05), or who felt poorly informed regarding CAM (P < .05), were more likely to use vitamins and supplements. Seventy-seven percent of patients described their quality of life as very good or excellent. CONCLUSIONS: The use of CAM in children with functional abdominal pain disorders is common, with a majority reporting a high quality of life. Our study underscores the importance of asking about CAM use and patient/family knowledge of these treatments. AD - Nationwide Children's Hospital, Columbus, OH. Electronic address: Steven.Ciciora@nationwidechildrens.org. Nationwide Children's Hospital, Columbus, OH; The Ohio State University College of Medicine, Department of Biomedical Informatics, Columbus, OH. Nationwide Children's Hospital, Columbus, OH. University of Miami Miller School of Medicine, Miami, FL. AN - 32798564 AU - Ciciora, S. L. AU - Yildiz, V. O. AU - Jin, W. Y. AU - Zhao, B. AU - Saps, M. DA - Dec DO - 10.1016/j.jpeds.2020.08.027 DP - NLM ET - 2020/08/18 KW - Abdominal Pain Academic Medical Centers Adolescent Child Complementary Therapies/*methods/psychology/statistics & numerical data Exercise Female Gastrointestinal Diseases/psychology/*therapy Health Knowledge, Attitudes, Practice Humans Male Probiotics/therapeutic use Quality of Life Surveys and Questionnaires Vitamins/therapeutic use *abdominal migraine *functional abdominal pain *functional dyspepsia *functional gastrointestinal disorders *gastroenterology *irritable bowel syndrome LA - eng N1 - 1097-6833 Ciciora, Steven L Yildiz, Vedat O Jin, Wendy Y Zhao, Becky Saps, Miguel Journal Article United States J Pediatr. 2020 Dec;227:53-59.e1. doi: 10.1016/j.jpeds.2020.08.027. Epub 2020 Aug 13. PY - 2020 SN - 0022-3476 SP - 53-59.e1 ST - Complementary and Alternative Medicine Use in Pediatric Functional Abdominal Pain Disorders at a Large Academic Center T2 - J Pediatr TI - Complementary and Alternative Medicine Use in Pediatric Functional Abdominal Pain Disorders at a Large Academic Center VL - 227 ID - 3822 ER - TY - JOUR AB - OBJECTIVES: There are only a handful of studies examining the clinical differences between patients with and without a family history of migraine. Our aim is to compare the descriptive and clinical properties of patients with and without a family history, and to investigate the association between the migraine burden and disease characteristics and disability of migraine. METHODS: A total of 530 consecutive patients diagnosed with migraine according to the International Headache Society criteria were enrolled into the study. Detailed systemic and neurological examinations, and blood pressure, weight, height, and body mass index measurements, clinical and demographical data, the visual analog scale, allodynia symptom checklist, and the Migraine Disability Assessment Scale (MIDAS) scores were recorded. The groups with and without a family history of migraine were compared statistically. RESULTS: Patients with a positive family history had a higher educational status (high school and higher) (p<0.05) and an increased triggering of pain with physical activity (p=0.013). The age at onset was earlier (p=0.049); disease duration was longer (p=0.030), and MIDAS scores were significantly higher (p=0.028) in patients with a family history of migraine. CONCLUSION: Having a family history of migraine is associated with an earlier age at onset and a longer disease duration, in addition to an increased disability in these patients. The family history may be assumed as a marker of the genetic load in migraineurs; therefore, an early diagnosis and an appropriate management are essential in these patients to avoid migraine-related disability. AD - Department of Neurology, Health Sciences University, Istanbul Training and Research Hospital, Istanbul, Turkey. Department of Neurology, Istanbul University Istanbul Faculty of Medicine, Headache Unit, Istanbul, Turkey. AN - 31736021 AU - Çimen Atalar, A. AU - Yalın, OÖ AU - Aslan, H. AU - Baykan, B. DA - Jul DO - 10.14744/agri.2019.26042 DP - NLM ET - 2019/11/19 IS - 3 KW - Adolescent Adult Age Factors Aged Aged, 80 and over Child Disability Evaluation Female *Genetic Predisposition to Disease Humans Hyperalgesia Male Middle Aged Migraine Disorders/*epidemiology/etiology/genetics Pedigree Socioeconomic Factors Turkey/epidemiology Visual Analog Scale Young Adult LA - tur N1 - Çimen Atalar, Arife Yalın, Osman Özgür Aslan, Hüsniye Baykan, Betül Journal Article Turkey Agri. 2019 Jul;31(3):113-121. doi: 10.14744/agri.2019.26042. OP - Ailede migren öyküsü bulunmasının migren özelliklerine etkisi nedir? PY - 2019 SN - 1300-0012 (Print) 1300-0012 SP - 113-121 ST - [What is the impact of having a family history of migraine on migraine characteristics?] T2 - Agri TI - [What is the impact of having a family history of migraine on migraine characteristics?] VL - 31 ID - 3477 ER - TY - JOUR AB - The Functional Disability Inventory (FDI; Walker LS, Greene JW. The functional disability inventory: measuring a neglected dimension of child health status. J Pediatr Psychol 1991; 16:39-58) assesses activity limitations in children and adolescents with a variety of pediatric conditions. This study evaluated the psychometric properties of the FDI in pediatric pain patients. Participants included 596 patients with chronic abdominal pain, ages 8-17, and a subset of their parents (n = 151) who completed the FDI and measures of pain, limitations in school activities, and somatic and depressive symptoms at a clinic visit. Test-retest reliability was high at 2 weeks (child report, .74; parent-report, .64) and moderate at 3 months (child report,.48; parent report,.39). Internal consistency reliability was excellent, ranging from .86 to .91. Validity was supported by significant correlations of child- and parent-report FDI scores with measures of school-related disability, pain, and somatic symptoms. Study results add to a growing body of empirical literature supporting the reliability and validity of the FDI for functional assessment of pediatric patients with chronic pain. (c) 2005 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved. AN - WOS:000236076000010 AU - Claar, R. L. AU - Walker, L. S. DA - Mar DO - 10.1016/j.pain.2005.12.002 IS - 1-2 N1 - Claar, RL Walker, LS PY - 2006 SN - 0304-3959 SP - 77-84 ST - Functional assessment of pediatric pain patients: Psychometric properties of the Functional Disability Inventory T2 - Pain TI - Functional assessment of pediatric pain patients: Psychometric properties of the Functional Disability Inventory UR - ://WOS:000236076000010 VL - 121 ID - 2739 ER - TY - JOUR AB - BACKGROUND: In Germany, about 70,000 teachers and educational staff were teaching at more than 3,000 special schools during the school year 2010/2011. Nursing services like lifting pupils form a substantial part of the work content of the staff at special schools. Since nursing care often involves carrying and lifting pupils, there is a reason to assume an adverse effect on the musculoskeletal health of teachers and other professionals. With the present study we aimed to describe the prevalence and risk factors of chronic back pain among employees at this type of school. METHODS: The cross-sectional survey was carried out between August 2010 and August 2012 at 13 special schools focusing on motoric and/or holistic development of handicapped children in Rhineland-Palatinate (Germany). Teachers and educational staff were interviewed using a questionnaire. We applied multivariable logistic regression analyses to identify influencing factors of chronic back pain. RESULTS: Altogether 395 persons (response rate: 59.7%) participated in our study. Respondents were mostly female (86.8%) with a mean age of 45 years. The prevalence of chronic back pain was 38.7%. More than 40% reported frequently carrying and lifting heavy loads (>20 kg). Age [adjusted OR = 1.03 (95%-CI 1.00-1.05) for 1-year increase in age], current smoking [adjusted OR = 2.31 (95%-CI 1.27-4.23)], depression/depressive mood [adjusted OR = 1.85 (95%-CI 1.12-3.06)], frequently carrying and lifting heavy loads [adjusted OR = 2.69 (95%-CI 1.53-4.75)], and frequent exposure to environmental impacts [adjusted OR = 2.18 (95%-CI 1.26-3.76)] were influencing factors of chronic back pain in the final multivariable regression model. CONCLUSIONS: A large proportion of teachers and educational staff suffered from chronic back pain in our study, indicating a high need for treatment in this professional group. Increasing age, current smoking, a diagnosed depression/depressive mood, carrying and lifting heavy loads, and exposure to environmental impacts were associated with chronic back pain. Due to the sparse literature on the topic, further studies using a longitudinal design are necessary for a better understanding of the risk factors of chronic back pain. AU - Claus, Matthias AU - Kimbel, Renate AU - Spahn, Daniel AU - Dudenhöffer, Sarah AU - Rose, Dirk-Matthias AU - Letzel, Stephan DA - 2014/02/25/ DO - 10.1186/1471-2474-15-55 DP - PubMed J2 - BMC Musculoskelet Disord KW - Adult Alcoholism Back Pain Body Mass Index Caregivers Child Chronic Pain Cross-Sectional Studies Depression Disabled Children Education, Special Female Germany Humans Male Middle Aged Moving and Lifting Patients Musculoskeletal Diseases Occupational Diseases Risk Factors Schools Smoking Socioeconomic Factors Teaching Workplace LA - eng PY - 2014 SN - 1471-2474 SP - 55 ST - Prevalence and influencing factors of chronic back pain among staff at special schools with multiple and severely handicapped children in Germany T2 - BMC musculoskeletal disorders TI - Prevalence and influencing factors of chronic back pain among staff at special schools with multiple and severely handicapped children in Germany: results of a cross-sectional study UR - http://www.ncbi.nlm.nih.gov/pubmed/24568286 VL - 15 ID - 87 ER - TY - JOUR AB - Objectives Spinal (ie, back and neck) pain often develops as early as during adolescence and can set a trajectory for later life. However, whether early-life spinal-pain-related behavioral responses of missing school/work are predictive of future work absenteeism is yet unknown. We assessed the association of adolescent spinal-pain-related work or school absenteeism with early adulthood work absenteeism in a prospective population-based cohort. Methods Six year follow-up data from the Western Australian Pregnancy Cohort (Raine) study were used (N=476; with a 54% response rate). At age 17, participants reported spinal pain (using the Nordic questionnaire) and adolescent spinal-pain-related work/school absenteeism (with a single item question). Annual total and health-related work absenteeism was assessed with the Health and Work Performance questionnaire distributed in four quarterly text messages during the 23rd year of age. We modelled the association of adolescent spinal-pain-related absenteeism with work absenteeism during early adulthood, using negative binomial regression adjusting for sex, occupation and comorbidities. Results Participants with adolescent low-back or neck pain with work/school absenteeism reported higher total work absenteeism in early adulthood [148.7, standard deviation (SD) 243.4 hours/year], than those without pain [43.7 (SD 95.2) hours/year); incidence rate ratio 3.4 (95% CI 1.2-9.2)]. Comparable findings were found when considering low-back and neck separately, and when considering health-related absenteeism. Conclusions We found a more than three-fold higher risk of work absenteeism in early adulthood among those with adolescent spinal-pain-related absenteeism, compared to those without. These findings suggest that, to keep a sustainable workforce, pain prevention and management should focus on pain-related behaviors as early as in adolescence. AN - WOS:000449167400009 AU - Coenen, P. AU - Smith, A. AU - Kent, P. AU - Harris, M. AU - Linton, S. J. AU - Pransky, G. AU - Beales, D. AU - O'Sullivan, P. AU - Straker, L. DO - 10.5271/sjweh.3744 IS - 5 N1 - Coenen, Pieter Smith, Anne Kent, Peter Harris, Mark Linton, Steven J. Pransky, Glenn Beales, Darren O'Sullivan, Peter Straker, Leon Harris, Mark/O-5084-2015; /B-2407-2013 Harris, Mark/0000-0002-1804-4357; /0000-0002-7786-4128 1795-990x PY - 2018 SN - 0355-3140 SP - 521-529 ST - The association of adolescent spinal-pain-related absenteeism with early adulthood work absenteeism: A six-year follow-up data from a population-based cohort T2 - Scandinavian Journal of Work Environment & Health TI - The association of adolescent spinal-pain-related absenteeism with early adulthood work absenteeism: A six-year follow-up data from a population-based cohort UR - ://WOS:000449167400009 VL - 44 ID - 2048 ER - TY - JOUR AB - BACKGROUND: Untreated immunization pain causes undue distress and contributes to underimmunization through physician, and possibly parental, resistance to multiple simultaneous injections. OBJECTIVE: To compare the efficacies of two pain management methods in reducing immediate immunization injection pain and distress in school-aged children. DESIGN: A randomized, controlled clinical trial of eutectic mixture of local anesthetics (EMLA) cream and vapocoolant spray. PATIENTS: Children aged 4 to 6 years and scheduled to receive diphtheria and tetanus toxoids and acellular pertussis vaccine (DTaP) during health supervision visits. INTERVENTIONS: Enrolled children were randomized to one of three treatment groups: 1) EMLA cream + distraction; 2) vapocoolant spray + distraction; or 3) distraction alone (control). The specific pharmacologic pain control interventions consisted of EMLA cream (2.5% lidocaine, 2.5% prilocaine [Astra Pharmaceutical Products, Inc, Westborough, MA] $15. 00/patient; applied 60 minutes before injection) and vapocoolant spray (Fluori-Methane [Gebauer Company, Cleveland, OH] $0. 50/patient; applied via spray-saturated cotton ball for 15 seconds immediately before injection). MAIN OUTCOME MEASURES: The blinded investigator (BI) measured (by edited videotape) cry duration and the number of pain behaviors using the Observational Scale of Behavioral Distress. Pain visual analog scales (linear and faces scales) were completed by the child, parent, nurse, and the BI. RESULTS: Sixty-two children, aged 4.5 +/- 0.4 years (mean +/- SD) were randomized. The three treatment groups had similar subject characteristics. All pain measures and cry duration were similar for EMLA and vapocoolant spray. Both EMLA and spray were significantly better than control. Results for spray vs control: cry duration (seconds): 8.5 +/- 21.0 vs 38.6 +/- 50.5; number of pain behaviors: 1.2 +/- 1.9 vs. 3.1 +/- 2.1; child-scored faces scale: 2.0 +/- 2.4 vs. 4.1 +/- 2.3; parent-scored faces scale: 1.6 +/- 1.6 vs. 3.0 +/- 1.7; nurse-scored faces scale: 1.6 +/- 1.2 vs. 3.1 +/- 1.4; and BI-scored faces scale: 1.0 +/- 1.5 vs. 2.4 +/- 1.4. CONCLUSIONS: When combined with distraction, vapocoolant spray significantly reduces immediate injection pain compared with distraction alone, and is equally effective as, less expensive, and faster-acting than EMLA cream. As an effective, inexpensive, and convenient pain control method, vapocoolant spray may help overcome physician and parent resistance to multiple injections that leads to missed opportunities to immunize. AU - Cohen Reis, E. AU - Holubkov, R. DA - 1997/12// DO - 10.1542/peds.100.6.e5 DP - PubMed IS - 6 J2 - Pediatrics KW - Age Factors Anesthetics, Local Attention Child Child, Preschool Chlorofluorocarbons, Methane Diphtheria-Tetanus-Pertussis Vaccine Female Humans Immunization Injections, Intramuscular Male Nebulizers and Vaporizers Pain Pain Measurement Treatment Outcome LA - eng PY - 1997 SN - 1098-4275 SP - E5 ST - Vapocoolant spray is equally effective as EMLA cream in reducing immunization pain in school-aged children T2 - Pediatrics TI - Vapocoolant spray is equally effective as EMLA cream in reducing immunization pain in school-aged children UR - http://www.ncbi.nlm.nih.gov/pubmed/9374583 VL - 100 ID - 123 ER - TY - JOUR AB - Background Dental anxiety is a common problem, related to dental pain, which contributes to irregular dental attendance and avoidance of dental care, resulting in poorer oral health during childhood. Aim To evaluate anxiety, pain and/or discomfort related to dental treatment in 5-to 12-year-old children examined during a public holiday. Methods This cross-sectional survey study was carried out with parental permission in 970 children of both sexes. Socioeconomic status, dental anxiety and dental pain experience data were obtained through a questionnaire answered by parents or guardians. Dental anxiety was measured using the dental anxiety questionnaire (DAQ). The statistical analyses were performed using Pearson's Chi-square test. The intra-examiner agreement was high (kappa = 0.80) and the inter-examiner was kappa = 0.79. Results The prevalence of dental anxiety was 39.4 % and that of a history of dental pain was 44.9 %. Dental anxiety among children was associated with the child never having had a dental appointment. Statistics The anxiety correlated positively with a history of dental pain (p < 0.001), the mother's low level of schooling (p = 0.037), parents' dental anxiety (p < 0.001), and negatively with visits to the dentist (p < 0.001). Conclusion A high percentage of children presented with dental anxiety and a history of dental pain. AN - WOS:000214119900004 AU - Colares, V. AU - Franca, C. AU - Ferreira, A. AU - Amorim, H. A. AU - Oliveira, M. C. A. DA - Feb DO - 10.1007/s40368-012-0001-8 IS - 1 N1 - Colares, V. Franca, C. Ferreira, A. Amorim Filho, H. A. Oliveira, M. C. A. de Andrade Amorim, Viviane Colares Soares/O-9320-2019 de Andrade Amorim, Viviane Colares Soares/0000-0003-2912-2100 1996-9805 PY - 2013 SN - 1818-6300 SP - 15-19 ST - Dental anxiety and dental pain in 5- to 12-year-old children in Recife, Brazil T2 - European Archives of Paediatric Dentistry TI - Dental anxiety and dental pain in 5- to 12-year-old children in Recife, Brazil UR - ://WOS:000214119900004 VL - 14 ID - 2386 ER - TY - JOUR AB - Juvenile primary fibromyalgia syndrome (JPFS) is a chronic musculoskeletal pain syndrome affecting children and adolescents. In part one of this review, we discussed the epidemiology, etiology, pathogenesis, clinical manifestations and diagnosis of JPFS. Part two focuses on the treatment and prognosis of JPFS. Early intervention is important. The standard of care is multidisciplinary, combining various modalities-most importantly, exercise and cognitive behavioral therapy. Prognosis varies and symptoms may persist into adulthood. AN - WOS:000651807300001 AU - Coles, M. L. AU - Uziel, Y. C7 - 74 DA - May DO - 10.1186/s12969-021-00529-x IS - 1 N1 - Coles, Maya Levy Uziel, Yosef 1546-0096 PY - 2021 ST - Juvenile primary fibromyalgia syndrome: A Review- Treatment and Prognosis T2 - Pediatric Rheumatology TI - Juvenile primary fibromyalgia syndrome: A Review- Treatment and Prognosis UR - ://WOS:000651807300001 VL - 19 ID - 1738 ER - TY - JOUR AB - Objective.-The aim of this prospective study is to assess the time lapse between the onset of recurring headache and the correct diagnosis in a cohort of pediatric patients attending an Italian children's headache center for the first time. Methods.-One hundred and one patients and parents, referred to the Pediatric Headache Centre of San Raffaele Hospital in Milan, Italy, underwent a semi-structured interview to ascertain features of headache since onset (clinical and family history, presence of childhood periodic syndromes, previously undergone instrumental exams and specialists' examinations before the correct diagnosis, past and current treatment). All patients were evaluated by expert neurologists and their headache was classified according to the International Classification of Headache Disorders II (2004). Results.-The median time delay from the onset of the first episode of recurrent headache to definite diagnosis was 20 months (interquartile range 12 to 36 months). A correlation with younger age and a more delayed headache diagnosis was found (r Spearman = 0.25; P = .039). An association between diagnostic delay and positive family history (median 24 months [12 to 48] vs 12 [6 to 24]; P = .014) or female gender (median 18 months [12 to 42] vs 12 [5 to 30]; P trend = .070) was also evident. Notably, 76 out of 101 patients referred to our Center received an appropriate diagnosis according to International Classification of Headache Disorders II at the time of our visit only. Of note, up to 21% of this group were previously misdiagnosed (for epilepsy 43%, sinusitis 38%, or other diseases 19%), a fact that contributed to a longer time of clinical assessment (median 39 months) before reaching a correct diagnosis. The other group of 80 patients (79%) did not receive a specific diagnosis and treatment, and were not studied until their symptom became chronic and disabling. Conclusion.-Pediatric headache is still under-diagnosed and not adequately considered as a health problem in the medical community as well as social settings. There is a need for educational programs regarding headache involving not only general practitioners, pediatricians, and neurologists, but also the general population. These are desirable in order to raise awareness of such a condition and, accordingly, treat children accurately. AN - WOS:000294548200008 AU - Colombo, B. AU - Dalla Libera, D. AU - De Feo, D. AU - Pavan, G. AU - Annovazzi, P. O. AU - Comi, G. DA - Sep DO - 10.1111/j.1526-4610.2011.01976.x IS - 8 N1 - Colombo, Bruno Dalla Libera, Dacia De Feo, Donatella Pavan, Giulia Annovazzi, Pietro Osvaldo Comi, Giancarlo Dalla Libera, Dacia/0000-0001-5028-4177; Annovazzi, Pietro/0000-0003-0279-0707 1526-4610 PY - 2011 SN - 0017-8748 SP - 1267-1273 ST - Delayed Diagnosis in Pediatric Headache: An Outpatient Italian Survey T2 - Headache TI - Delayed Diagnosis in Pediatric Headache: An Outpatient Italian Survey UR - ://WOS:000294548200008 VL - 51 ID - 2479 ER - TY - JOUR AB - OBJECTIVE: Optimal diagnosis and management of median arcuate ligament (MAL) syndrome (MALS) remains unclear in contemporary practice. The advent and evolution of laparoscopic and endovascular techniques has redirected management toward a less invasive therapeutic algorithm. This study examined our contemporary outcomes of patients treated for MALS. METHODS: All patients treated for MALS at Dartmouth-Hitchcock Medical Center from 2000 to 2013 were retrospectively reviewed. Demographics and comorbidities were recorded. Freedom from symptoms and freedom from reintervention were the primary end points. Return to work or school was assessed. Follow-up by clinic visits and telephone allowed quantitative comparisons among the patients. RESULTS: During the study interval, 21 patients (24% male), with a median age of 42 years, were treated for MALS. All patients complained of abdominal pain in the presence of a celiac stenosis, 16 (76%) also reported weight loss at the time of presentation, and 57% had a concomitant psychiatric history. Diagnostic imaging most commonly used included duplex ultrasound (81%), computed tomography angiography (66%), angiography (57%), and magnetic resonance angiography (5%). Fourteen patients (67%) underwent multiple diagnostic studies. All patients underwent initial laparoscopic MAL release. Seven patients (33%) underwent subsequent celiac stent placement in the setting of recurrent or unresolved symptoms with persistent celiac stenosis at a mean interval of 49 days. Two patients required surgical bypass after an endovascular intervention failed. The 6-month freedom from symptoms was 75% and freedom from reintervention was 64%. Eighteen patients (81%) reported early symptom improvement and weight gain, and 66% were able to return to work. CONCLUSIONS: A multidisciplinary treatment approach using initial laparoscopic release and subsequent stent placement and bypass surgery provides symptom improvement in most patients treated for MALS. The potential placebo effect, however, remains uncertain. A significant minority of patients will require reintervention, justifying longitudinal surveillance and prudent patient selection. Patients can anticipate functional recovery, weight gain, and return to work with treatment. AD - Section of Vascular Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, NH. Electronic address: jesse.a.columbo@hitchcock.org. Section of Minimally Invasive Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, NH. Section of Vascular Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, NH. AN - 25758451 AU - Columbo, J. A. AU - Trus, T. AU - Nolan, B. AU - Goodney, P. AU - Rzucidlo, E. AU - Powell, R. AU - Walsh, D. AU - Stone, D. C2 - PMC5292272 C6 - NIHMS844838 DA - Jul DO - 10.1016/j.jvs.2015.01.050 DP - NLM ET - 2015/03/12 IS - 1 KW - Abdominal Pain/etiology Academic Medical Centers Adolescent Adult Aged *Angioplasty, Balloon/adverse effects/instrumentation Celiac Artery/*abnormalities/surgery Constriction, Pathologic/complications/diagnosis/*surgery Decompression, Surgical/adverse effects/*methods Diagnostic Imaging/methods Female Humans *Laparoscopy/adverse effects Male Median Arcuate Ligament Syndrome Middle Aged New Hampshire Predictive Value of Tests Recurrence Retrospective Studies Return to Work Stents Time Factors Treatment Outcome Weight Gain Weight Loss Young Adult LA - eng N1 - 1097-6809 Columbo, Jesse A Trus, Thadeus Nolan, Brian Goodney, Philip Rzucidlo, Eva Powell, Richard Walsh, Daniel Stone, David K08 HL105676/HL/NHLBI NIH HHS/United States Journal Article J Vasc Surg. 2015 Jul;62(1):151-6. doi: 10.1016/j.jvs.2015.01.050. Epub 2015 Mar 7. PY - 2015 SN - 0741-5214 (Print) 0741-5214 SP - 151-6 ST - Contemporary management of median arcuate ligament syndrome provides early symptom improvement T2 - J Vasc Surg TI - Contemporary management of median arcuate ligament syndrome provides early symptom improvement VL - 62 ID - 3880 ER - TY - JOUR AB - Introduction: Infliximab is a promising advance in the treatment of pediatric inflammatory bowel disease. Infliximab is an effective therapy for selected children with Crohn disease but is both costly and time consuming. Objectives: To analyze our center's experience with a program of home-based infliximab infusion. Methods: Between September, 2001, and October, 2003 we reviewed the charts of all children receiving home infliximab infusions focusing on cost, safety, and patient satisfaction. Children were enrolled in the home infusion program if they were compliant with hospital-based infliximab infusions and other medications, had no adverse events during hospital-based infliximab infusions, were in remission and had access to experienced pediatric homecare nursing. \ Results: Ten children received 59 home infusions with a dose range of 7.5 to 10 mg/kg/dose. The calculated average savings per patient was $1335/100 mg infliximab. Home infusions ranged from 2 to 5 hours. Since infusions could be performed any day of the week, school absenteeism was decreased. The average patient satisfaction rating for home infusions was 9 on a scale from 1 to 10 (10 = most satisfied). Three patients experienced difficulty with IV access requiring multiple attempts, but all were able to receive their infusions. One infusion was stopped because of arm pain above the IV site. This patient had his next infusion in the hospital before returning to the home infusion program. No severe adverse events (palpitations, blood pressure instability, hyperemia, respiratory symptoms) occurred during home infusions. Conclusions: In our carefully selected patients, infliximab infusions administered at home were safe and are cost-effective. Patients and families preferred home infusions, since time missed from school and work was reduced. AN - WOS:000226148300012 AU - Condino, A. A. AU - Fidanza, S. AU - Hoffenberg, E. J. DA - Jan DO - 10.1097/00005176-200501000-00012 IS - 1 N1 - Condino, AA Fidanza, S Hoffenberg, EJ Hoffenberg, Edward/0000-0001-5179-489X 1536-4801 PY - 2005 SN - 0277-2116 SP - 67-69 ST - A home infliximab infusion program T2 - Journal of Pediatric Gastroenterology and Nutrition TI - A home infliximab infusion program UR - ://WOS:000226148300012 VL - 40 ID - 2777 ER - TY - JOUR AB - OBJECTIVE: To determine preliminary outcomes of a treatment for refractory pediatric migraine that integrates outpatient dihydroergotamine (DHE) infusion with interdisciplinary adjunctive care. BACKGROUND: Limited data are available to inform treatment of refractory migraine in children. Intravenous DHE therapy has shown promise but has been implemented in costly inpatient settings and in isolation of nonpharmacological strategies shown to enhance analgesia and functional improvement. METHODS: We conducted a retrospective chart review of 36 patients ages 11-18 with refractory migraine who underwent a pilot treatment program in an outpatient neurology clinic. The treatment integrated up to 5 days of outpatient DHE infusion with adjunctive nonpharmacological care (pain coping skills training, massage, aromatherapy, and school reintegration support). Changes in headache, healthcare utilization, and functional limitations were assessed as indicators of treatment response through 3-month follow-up. RESULTS: On average, headache intensity declined (M = 5.8 ± 2.5 to M = 2.4 ± 2.7; P < .0001) during the treatment period and remained statistically significantly improved through 3-month follow-up. Headache frequency decreased by a mean of 1.5 days per week (M = 6.7 ± 1.0 vs M = 5.2 ± 2.7, P = .012) through 3-month follow-up, with a 27% reduction (from 0.91 to 0.66) in the proportion of patients reporting a continuous headache (P = .009). Over this same follow-up period, there was a reduction in school days missed per month (median [25th, 75th percentile]: 4.5 [0, 21.0] vs 0 [0.0, 0.5]). There also were reductions in headache-related visits per month to the emergency department and medical providers. Adverse effects were common but typically minor and transient. CONCLUSIONS: Combining outpatient DHE infusion with interdisciplinary adjunctive care has promise as an effective treatment option for adolescents with refractory migraine. AD - Division of Developmental and Behavioral Sciences, Children's Mercy Hospital, Kansas City, MO, USA. University of Missouri Kansas City School of Medicine, Kansas City, MO, USA. Division of Neurology, Children's Mercy Hospital, Kansas City, MO, USA. AN - 31626335 AU - Connelly, M. AU - Sekhon, S. AU - Stephens, D. AU - Boorigie, M. AU - Bickel, J. DA - Jan DO - 10.1111/head.13685 DP - NLM ET - 2019/10/19 IS - 1 KW - Adolescent *Ambulatory Care Analgesics, Non-Narcotic/*administration & dosage *Aromatherapy Child *Clinical Protocols Combined Modality Therapy Dihydroergotamine/*administration & dosage Female Follow-Up Studies Humans Infusions, Intravenous Male *Massage Migraine Disorders/drug therapy/physiopathology/*therapy *Outcome Assessment, Health Care Outpatient Clinics, Hospital Pilot Projects *Psychotherapy Retrospective Studies Schools Social Support *dihydroergotamine *interdisciplinary *nonpharmacological treatment *pediatric *refractory migraine LA - eng N1 - 1526-4610 Connelly, Mark Orcid: 0000-0001-8157-8901 Sekhon, Subhjit Stephens, Dane Boorigie, Madeline Bickel, Jennifer Journal Article United States Headache. 2020 Jan;60(1):101-109. doi: 10.1111/head.13685. Epub 2019 Oct 18. PY - 2020 SN - 0017-8748 SP - 101-109 ST - Enhancing Outpatient Dihydroergotamine Infusion With Interdisciplinary Care to Treat Refractory Pediatric Migraine: Preliminary Outcomes From the Comprehensive Aggressive Migraine Protocol ("CAMP") T2 - Headache TI - Enhancing Outpatient Dihydroergotamine Infusion With Interdisciplinary Care to Treat Refractory Pediatric Migraine: Preliminary Outcomes From the Comprehensive Aggressive Migraine Protocol ("CAMP") VL - 60 ID - 3053 ER - TY - JOUR AB - IntroductionEntrapment neuropathies are infrequent in children, and therefore remain unrecognized. The incidence of radial, median, and cubital mononeuropathies are all similar. Despite the rarity of such cases, extensive, albeit scattered, literature has accumulated concerning entrapment neuropathies in children.ObjectiveTo the literature concerning entrapment neuropathies in children.MethodsA systematic review of the existing literature has been made.ResultsThe management of chronic pediatric pain is very important in such patients to prevent youths from experiencing prolonged absences from school, sports, or other productive activities, and limit the psychological burden of chronic disease. Nonsurgical treatment of both cubital and carpal tunnel syndromes has been disappointing in pediatric patients, with only limited success; and, to date, there is no clear explanation for the outcome differences generated by nonsurgical management between adults and youths. Simple decompression of the ulnar nerve at the elbow also has much higher rates of failure in children than in adults.ConclusionsThe presence of an entrapment neuropathy (specially carpal tunnel syndrome) in a pediatric-age patient should alert medical care providers to the potential of some underlying genetic condition or syndrome. AN - WOS:000456311300008 AU - Costales, J. R. AU - Socolovsky, M. AU - Lazaro, J. A. S. AU - Costales, D. R. DA - Jan DO - 10.1007/s00381-018-3975-7 IS - 1 N1 - Robla Costales, Javier Socolovsky, Mariano Sanchez Lazaro, Jaime A. Robla Costales, David Sanchez-Lazaro, Jaime/AAH-4937-2020; Socolovsky, Mariano/V-1568-2019 Sanchez-Lazaro, Jaime/0000-0002-6517-7101; Robla, David/0000-0003-1246-2918; Socolovsky, Mariano/0000-0002-0667-3463 1433-0350 PY - 2019 SN - 0256-7040 SP - 37-45 ST - Peripheral nerve injuries in the pediatric population: a review of the literature. Part II: entrapment neuropathies T2 - Childs Nervous System TI - Peripheral nerve injuries in the pediatric population: a review of the literature. Part II: entrapment neuropathies UR - ://WOS:000456311300008 VL - 35 ID - 1970 ER - TY - JOUR AB - BACKGROUND: Complementary or integrative care therapies are promising adjunctive approaches to pain management for pediatric inpatients that are currently underused and understudied. The purpose of this study was to examine the potential benefits of integrative care therapies delivered to hospitalized children and adolescents at a large Midwestern academic pediatric medical center over a 1-year period. METHODS: A retrospective chart review of an inpatient clinical database maintained by integrative care therapists over a 1-year period was used for the current study. Pre/post pain and relaxation scores associated with the delivery of inpatient integrative care therapies (primarily massage therapy and healing touch) were examined. RESULTS: Five-hundred nineteen hospitalized children and adolescents were treated by integrative care therapists for primarily pain or anxiety needs. Patients had a mean age of 10.2 years (standard deviation, 7.0), 224 were female (43%), 383 were white (74%), and most (393 [77%]) received massage therapy. Mean pain and relaxation scores decreased significantly from pre- to post-therapy across all demographic and clinical subgroups (p≤.001). CONCLUSIONS: Although integrative care therapies are increasingly requested and offered in children's hospitals, provision of these approaches is driven primarily by consumer demand rather than evidence-informed practice. Future controlled studies should examine the incremental effects of integrative care therapies as an adjunct to conventional treatment, assess how these therapies work mechanistically, and determine whether they improve outcomes, such as pain and cost, for hospitalized children and adolescents. AD - 1 Department of Family and Community Medicine, Division of Integrative Medicine, Department of Pediatrics, University of Cincinnati College of Medicine , Cincinnati, OH. AN - 24175871 AU - Cotton, S. AU - Luberto, C. M. AU - Bogenschutz, L. H. AU - Pelley, T. J. AU - Dusek, J. C2 - PMC3924796 DA - Feb DO - 10.1089/acm.2013.0306 DP - NLM ET - 2013/11/02 IS - 2 KW - Adolescent Adolescent, Hospitalized/psychology/*statistics & numerical data Anxiety/therapy Child Child, Hospitalized/psychology/*statistics & numerical data Complementary Therapies/*methods Female Humans Integrative Medicine/*methods Male Pain Management/methods/*statistics & numerical data Retrospective Studies LA - eng N1 - 1557-7708 Cotton, Sian Luberto, Christina M Bogenschutz, Lois H Pelley, Terri J Dusek, Jeffrey R01 AT006518/AT/NCCIH NIH HHS/United States Journal Article Research Support, Non-U.S. Gov't J Altern Complement Med. 2014 Feb;20(2):98-102. doi: 10.1089/acm.2013.0306. Epub 2013 Oct 31. PY - 2014 SN - 1075-5535 (Print) 1075-5535 SP - 98-102 ST - Integrative care therapies and pain in hospitalized children and adolescents: a retrospective database review T2 - J Altern Complement Med TI - Integrative care therapies and pain in hospitalized children and adolescents: a retrospective database review VL - 20 ID - 3205 ER - TY - JOUR AB - Objectives.-To examine the feasibility of administering behavioral migraine management training by telephone (TAT) and the acceptability of TAT to adolescents with episodic migraine. Methods.-34 adolescents (M = 14 years) with migraine (M = 3.6 migraines/month; M = 29.2 hours duration) were randomly assigned to a two-month telephone administered behavioral migraine management program (TAT) or to a standard Triptan Treatment (TT). Outcome was assessed at three- and eight-month evaluations. Participants completed a daily migraine diary that yielded information about number, duration and severity of migraines and migraine-related disability, as well as the Migraine Specific Quality of Life Questionnaire - Adolescent. In addition, TAT participants evaluated key aspects of the TAT program using 5-point Likert-like rating scales. Lastly, the ability of adolescents to demonstrate specific headache management skills following TAT was assessed. Results.-All fifteen adolescents who entered TAT successfully demonstrated either full or partial mastery of two or more skills and nearly half demonstrated at least partial mastery of all four skills evaluated. Ninety three percent of the TAT participants reported having a positive relationship with their phone counselor. They also reported a preference for the telephone-based treatment over in-clinic visits and rated the manual and tapes as helpful. Treatment effects (in terms of percent improvement) ranged from consistently large across both evaluations for improvement in number of migraines (54% and 71%), disability equivalent hours (80% and 63%) and quality of life (44% and 48%), to moderate or variable for migraine duration (35% and 23%) and severity (30% and 34%). The TT group also showed clinically meaningful reductions in headache parameters and improvements in quality of life. Conclusions.-Completion rates for TAT were high; adolescents evaluated their experience with TAT positively and were able to exhibit key behavioral headache management skills following treatment. While clinically significant improvements in migraine and migraine-related disability/quality of life were observed with both TAT and treatment as usual (triptan therapy), the small study size and the absence of a control group do not permit conclusions about the effectiveness of either treatment. Nonetheless these results indicate TAT may be a promising treatment format for improving access to behavioral treatments for underserved adolescents and justifies further evaluation of TAT both alone and in combination with drug therapy. AN - WOS:000250079500004 AU - Cottrell, C. AU - Drew, J. AU - Gibson, J. AU - Holroyd, K. AU - O'Donnell, F. DA - Oct DO - 10.1111/j.1526-4610.2007.00804.x IS - 9 N1 - Cottrell, Constance Drew, Jana Gibson, Jessica Holroyd, Kenneth O'Donnell, Francis 1526-4610 PY - 2007 SN - 0017-8748 SP - 1293-1302 ST - Feasibility assessment of telephone-administered behavioral treatment for adolescent migraine T2 - Headache TI - Feasibility assessment of telephone-administered behavioral treatment for adolescent migraine UR - ://WOS:000250079500004 VL - 47 ID - 2677 ER - TY - JOUR AB - OBJECTIVE: To examine depression and baseline neurocognitive function and concussion symptoms in male and female high school and college athletes. DESIGN: Cross sectional. SETTING: Athletes completed testing at a designated computer laboratory at high schools and colleges. PARTICIPANTS: Participants included 1616 collegiate (n = 837) and high school (n = 779) athletes from 3 states participating in a variety of competitive sports. INTERVENTIONS: Participants completed the baseline Immediate Postconcussion Assessment and Cognitive Test (ImPACT), symptom inventory, and Beck Depression Inventory II (BDI-II). MAIN OUTCOME MEASURES: Between-group comparisons for depression groups on ImPACT composite scores (verbal and visual memory, reaction time, motor processing speed), total symptoms, and symptom cluster (sleep, cognitive, emotional, somatic/migraine) scores. Between-group comparisons for age and sex on BDI-II, ImPACT, total symptoms, and symptom cluster scores. RESULTS: The severe depression group scored worse on visual memory and reported more total, somatic/migraine, cognitive, emotional, and sleep symptoms than less depressed groups. High school athletes reported more somatic/migraine symptoms than collegiate athletes, whereas collegiate athletes reported more emotional and sleep symptoms than high school athletes. Women had higher verbal memory and reported more cognitive, emotional, and sleep symptom clusters compared with men. Women outperformed men on verbal memory, whereas collegiate athletes outperformed high school athletes on processing speed. CONCLUSIONS: Athletes with severe depression scored lower on visual memory than those with minimal depression. Athletes with severe depression report more concussion symptoms than athletes with minimal and moderate depression scores. Symptoms of depression should be included in baseline assessments to help disentangle depression from concussion symptoms. AD - Department of Kinesiology, Michigan State University, East Lansing, Michigan 48824, USA. covassin@msu.edu AN - 22246342 AU - Covassin, T. AU - Elbin, R. J., 3rd AU - Larson, E. AU - Kontos, A. P. DA - Mar DO - 10.1097/JSM.0b013e31823403d2 DP - NLM ET - 2012/01/17 IS - 2 KW - Adolescent Age Factors Analysis of Variance Athletes Athletic Injuries/*diagnosis/physiopathology Brain Concussion/*diagnosis/physiopathology Cognitive Dysfunction/*diagnosis/physiopathology Cross-Sectional Studies Depression/*diagnosis/physiopathology Female Humans Male Migraine Disorders/diagnosis/physiopathology Neurologic Examination *Neuropsychological Tests Severity of Illness Index Sex Factors Sleep Wake Disorders/diagnosis/physiopathology Young Adult LA - eng N1 - 1536-3724 Covassin, Tracey Elbin, Robert J 3rd Larson, Elizabeth Kontos, Anthony P Journal Article United States Clin J Sport Med. 2012 Mar;22(2):98-104. doi: 10.1097/JSM.0b013e31823403d2. PY - 2012 SN - 1050-642x SP - 98-104 ST - Sex and age differences in depression and baseline sport-related concussion neurocognitive performance and symptoms T2 - Clin J Sport Med TI - Sex and age differences in depression and baseline sport-related concussion neurocognitive performance and symptoms VL - 22 ID - 3761 ER - TY - JOUR AB - BACKGROUND: Multiple concussions have been associated with prolonged symptoms, recovery time, and risk for future concussions. However, very few studies have examined the effect of multiple concussions on neurocognitive performance and the recently revised symptom clusters using a large database. PURPOSE: To examine concussed athletes with a history of 0, 1, 2, or ≥3 concussions on neurocognitive performance and the recently revised symptom clusters. STUDY DESIGN: Cohort study (prognosis); Level of evidence, 2. METHODS: The independent variables were concussion group (0, 1, 2, and ≥3 concussions) and time (baseline, 3 days, and 8 days). The dependent variables were neurocognitive test scores as measured by the Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) neurocognitive test battery (verbal and visual memory, processing speed, and reaction time) and 4 concussion symptom clusters (migraine-cognitive-fatigue, affective, somatic, and sleep). All concussed athletes (n = 596) were administered the ImPACT test at a mean 2.67 ± 1.98 and 7.95 ± 4.46 days after injury. A series of 4 (concussion group) × 3 (time) repeated-measures analyses of covariance (age = covariate) were performed on ImPACT composite scores and symptom clusters. RESULTS: Concussed athletes with ≥3 concussions were still impaired 8 days after a concussion compared with baseline scores on verbal memory (P < .001), reaction time (P < .001), and migraine-cognitive-fatigue symptoms (P < .001). There were no significant findings on the remaining dependent variables. CONCLUSION: Concussed athletes with a history of ≥3 concussions take longer to recover than athletes with 1 or no previous concussion. Future research should concentrate on validating the new symptom clusters on multiple concussed athletes, examining longer recovery times (ie, >8 days) among athletes with multiple concussions. AD - Tracey Covassin, AT, Department of Kinesiology, Michigan State University, 308 West Circle Drive, Room 105, East Lansing, MI 48824. covassin@msu.edu. AN - 23959963 AU - Covassin, T. AU - Moran, R. AU - Wilhelm, K. DA - Dec DO - 10.1177/0363546513499230 DP - NLM ET - 2013/08/21 IS - 12 KW - Adolescent Adult Affect Athletes/psychology Athletic Injuries/complications/*psychology Brain Concussion/complications/*psychology *Cognition Cognition Disorders/*etiology/prevention & control Cohort Studies Fatigue/etiology Female Humans Incidence Male *Memory Migraine Disorders/etiology Neuropsychological Tests *Reaction Time Schools Sleep Young Adult cognitive testing multiple concussions symptoms LA - eng N1 - 1552-3365 Covassin, Tracey Moran, Ryan Wilhelm, Kristyn Journal Article United States Am J Sports Med. 2013 Dec;41(12):2885-9. doi: 10.1177/0363546513499230. Epub 2013 Aug 19. PY - 2013 SN - 0363-5465 SP - 2885-9 ST - Concussion symptoms and neurocognitive performance of high school and college athletes who incur multiple concussions T2 - Am J Sports Med TI - Concussion symptoms and neurocognitive performance of high school and college athletes who incur multiple concussions VL - 41 ID - 3860 ER - TY - JOUR AB - OBJECTIVES: To assess the effects of a 9-week yoga intervention on chronic nonspecific neck pain 12 months after completion. DESIGN: Twelve-month follow-up of the pooled data of both arms of a randomized, controlled trial. SETTING: Department of Internal and Integrative Medicine at an academic teaching hospital. SUBJECTS: Fifty-one patients with chronic nonspecific neck pain (mean age 47.8 years; 82.4% female). INTERVENTIONS: A 9-week yoga group intervention. OUTCOME MEASURES: Neck pain intensity (100-mm visual analog scale), functional disability (neck disability index), health-related quality of life (short-form 36 questionnaire, SF-36), generic disability (days with restricted activities), and global improvement. RESULTS: From baseline to 12-month follow-up, pain intensity improved from 48.81 ± 17.71 to 32.31 ± 20.68 (P < 0.001), neck-related disability decreased from 25.26 ± 9.02 to 19.49 ± 11.52 (P = 0.001), and bodily pain in the SF-36 improved from 49.37 ± 12.40 to 59.26 ± 17.57 (P = 0.005). Improvements in pain intensity were predicted by weekly minutes of yoga practice during the past 4 weeks (r(2)  = 0.12, P = 0.028); improved neck-related disability (r(2)  = 0.24, P = 0.001) and bodily pain (r(2)  = 0.26, P = 0.006) were predicted by regular yoga practice during the past 12 months. Generic disability did not decrease significantly. Twenty-four patients (68.6%) rated their health as at least somewhat improved. CONCLUSIONS: A 9-week yoga intervention improved pain and neck-related disability for at least 12 months after completion. Sustained yoga practice seems to be the most important predictor of long-term effectiveness. AD - Department of Internal and Integrative Medicine, Kliniken Essen-Mitte, Faculty of Medicine, University of Duisburg-Essen, Essen, Germany. h.cramer@kliniken-essen-mitte.de AN - 23387504 AU - Cramer, H. AU - Lauche, R. AU - Hohmann, C. AU - Langhorst, J. AU - Dobos, G. DA - Apr DO - 10.1111/pme.12053 DP - NLM ET - 2013/02/08 IS - 4 KW - Adolescent Adult Chronic Disease Disability Evaluation Educational Status Female Follow-Up Studies Humans Male Middle Aged Neck Pain/*therapy Pain Measurement Patient Compliance Quality of Life Regression Analysis Socioeconomic Factors Treatment Outcome *Yoga Young Adult LA - eng N1 - 1526-4637 Cramer, Holger Lauche, Romy Hohmann, Claudia Langhorst, Jost Dobos, Gustav Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't England Pain Med. 2013 Apr;14(4):541-8. doi: 10.1111/pme.12053. Epub 2013 Feb 6. PY - 2013 SN - 1526-2375 SP - 541-8 ST - Yoga for chronic neck pain: a 12-month follow-up T2 - Pain Med TI - Yoga for chronic neck pain: a 12-month follow-up VL - 14 ID - 3714 ER - TY - JOUR AB - OBJECTIVE: The aim of this study was to evaluate the incidence of anxiety and rates of anxiety treatment in emergency department (ED) patients presenting with pain-related complaints. METHODS: We prospectively evaluated patients in an urban academic tertiary care hospital ED from 2000 through 2010. We enrolled a convenience sample of adult patients presenting with pain and recorded patient complaint, medication administration, satisfaction, and pain and anxiety scores throughout their stay. We stratified patients into 4 different groups according to anxiety score at presentation (0, none; 1-4, mild; 5-7, moderate; 8-10, severe). RESULTS: We enrolled 10 664 ED patients presenting with pain-related complaints. Patients reporting anxiety were as follows: 25.7%, none; 26.1%, mild; 23.7%, moderate; and 24.5%, severe. Although 48% of patients described moderate to severe anxiety at ED presentation and 60% were willing to take a medication for anxiety, only 1% received anxiety treatment. Thirty-five percent of patients still reported moderate/severe anxiety at discharge. Severe anxiety at ED presentation was associated with increased demand for pain medication (odds ratio [OR], 1.40; 95% confidence interval [CI], 1.10-1.79) and anxiety medication (OR, 4.34; 95% CI, 3.68-5.11) during the ED stay and decreased satisfaction with the treatment of pain (β coefficient = -0.328; P < .001). After adjusting for age, sex, and presentation pain scores, patients who reported severe anxiety were more likely to receive an analgesic (OR, 1.33; 95% CI, 1.19-1.50) and an opioid (OR, 1.25; 95% CI, 1.11-1.41) during the ED stay. CONCLUSION: Anxiety may be underrecognized and undertreated in patients presenting with pain-related complaints. Patients reporting severe anxiety were less likely to report satisfaction with the treatment of their pain, despite higher rates of analgesic administration. AD - University of Utah, Salt Lake City, UT 84132, USA. Philip.craven@hsc.utah.edu AN - 22981626 AU - Craven, P. AU - Cinar, O. AU - Madsen, T. DA - Feb DO - 10.1016/j.ajem.2012.08.009 DP - NLM ET - 2012/09/18 IS - 2 KW - Adolescent Adult Analgesics/*therapeutic use Anxiety/*complications/diagnosis/drug therapy/epidemiology *Emergency Service, Hospital Female Humans Incidence Logistic Models Male Middle Aged Multivariate Analysis Pain/complications/*drug therapy/psychology Pain Management/*psychology Pain Measurement Patient Satisfaction/statistics & numerical data Prospective Studies Self Report Severity of Illness Index Treatment Outcome Young Adult LA - eng N1 - 1532-8171 Craven, Philip Cinar, Orhan Madsen, Troy Clinical Trial Journal Article United States Am J Emerg Med. 2013 Feb;31(2):313-8. doi: 10.1016/j.ajem.2012.08.009. Epub 2012 Sep 13. PY - 2013 SN - 0735-6757 SP - 313-8 ST - Patient anxiety may influence the efficacy of ED pain management T2 - Am J Emerg Med TI - Patient anxiety may influence the efficacy of ED pain management VL - 31 ID - 3829 ER - TY - JOUR AB - This study investigated the community integration, self-esteem, and vocational identity of 106 persons with disabilities, most of whom were unemployed and attending a vocational rehabilitation agency. Community integration was mediated by type of disability; that is, community integration levels were significantly greater among persons with a psychiatric disability and those with physical (non-pain) or sensory disabilities, than among those with acquired brain injury or chronic pain. Higher levels of self-esteem were reported by persons with chronic pain, physical (non-pain), or sensory disabilities than among persons with acquired brain injury or a psychiatric disability. Persons who regularly received both vocational and psychological/psychiatric services reported significantly lower levels of self-esteem and vocational identity than those persons who received vocational services only. Community integration was, however, independent of type of service received. Implications for rehabilitation professionals are discussed. AN - WOS:A1996UY81600009 AU - Crisp, R. DA - Jul DO - 10.1080/00050069608260193 IS - 2 N1 - Crisp, R PY - 1996 SN - 0005-0067 SP - 133-137 ST - Community integration, self-esteem, and vocational identity among persons with disabilities T2 - Australian Psychologist TI - Community integration, self-esteem, and vocational identity among persons with disabilities UR - ://WOS:A1996UY81600009 VL - 31 ID - 2925 ER - TY - JOUR AB - Functional somatic symptoms signal distress and reflect an activation of the body's stress-regulation systems. Many different types of stressors - physical, emotional or both - may activate the body's stress-regulation systems. If stress-related disruptions are extreme or are not limited in time, functional somatic symptoms may emerge, signalling that the body remains in a state of activation and somatic distress. In this paper, we describe the development of therapeutic fact sheets, which are used as part of our multimodal, family-based, rehabilitation intervention for children and adolescents presenting with functional somatic symptoms. The fact sheets provide information about functional somatic symptoms - including their assessment and treatment - from a stress-system framework. They are used in the context of a family intervention to facilitate engagement with the family and to reduce parental anxiety and reactivity. Whilst the fact sheets were initially developed for parents, over time we found that the sheets were also useful in managing anxiety in the medical and school systems. A key goal of this article is to share this resource with other clinicians working with children/adolescents with functional somatic symptoms. AN - WOS:000344475700004 AU - Cruz, C. AU - Chudleigh, C. AU - Savage, B. AU - Kozlowska, K. DA - Sep DO - 10.1002/anzf.1059 IS - 3 N1 - Cruz, Catherine Chudleigh, Catherine Savage, Blanche Kozlowska, Kasia 1467-8438 PY - 2014 SN - 0814-723X SP - 223-243 ST - Therapeutic Use of Fact Sheets in Family Therapy with Children and Adolescents With Functional Somatic Symptoms T2 - Australian and New Zealand Journal of Family Therapy TI - Therapeutic Use of Fact Sheets in Family Therapy with Children and Adolescents With Functional Somatic Symptoms UR - ://WOS:000344475700004 VL - 35 ID - 2289 ER - TY - JOUR AB - We reviewed the referral pattern of children with chronic pain to a specialized pediatric pain clinic. Data were obtained from referring physicians and medical records and during an interview with patients and their parents by physicians and a psychologist. We analyzed the following: referral diagnosis, demographics, duration of symptoms, number of physicians previously consulted, school attendance, sports activities, presence of psychological disorders, final team diagnosis, and outcomes. Children had been experiencing pain for 34 +/- 55 months. Patients had consulted on average 3 physicians in addition to their pediatrician. 32% of the patients had missed at least 10 days of school in a calendar year, and 47% had stopped playing sports. 15% had an operation because of pain that had been unsuccessful. The most common missed diagnosis was anxiety (25%) and depression (13%). 69% of the patients were back to school and/or playing sports within 4 months from our initial consultation. 32% of the patients did not make any progress during the follow-up period. The most common reasons for failure to improve were no compliance with the recommended treatments and poorly controlled major mood disorder. The time to refer children with chronic pain for specialized care could be extremely long causing significant social and psychological consequence. AN - WOS:000396887000001 AU - Cucchiaro, G. AU - Schwartz, J. AU - Hutchason, A. AU - Ornelas, B. C7 - 8769402 DO - 10.1155/2017/8769402 N1 - Cucchiaro, Giovanni Schwartz, Jennifer Hutchason, Alec Ornelas, Beatriz 1687-9759 PY - 2017 SN - 1687-9740 SP - 1-7 ST - Chronic Pain in Children: A Look at the Referral Process to a Pediatric Pain Clinic T2 - International Journal of Pediatrics TI - Chronic Pain in Children: A Look at the Referral Process to a Pediatric Pain Clinic UR - ://WOS:000396887000001 VL - 2017 ID - 2122 ER - TY - JOUR AB - Pain behaviors are important indicators of functioning in chronic pain; however, no self-reported pain behavior instrument has been developed for pediatric populations. The purpose of this study was to create a brief pediatric measure of patient-reported pain behaviors as part of the Patient-Reported Outcome Measurement Information System (PROMIS). A pool of 47 candidate items for this measure had been previously developed through qualitative research. In this study, youth with chronic pain associated with juvenile fibromyalgia, juvenile idiopathic arthritis, or sickle cell disease (ages 8-18 years) from 3 pediatric centers completed all 47 candidate items for development of the pain behavior item bank along with established measures of pain interference, depressive symptoms, fatigue, average pain intensity, and pain catastrophizing. Caregivers reported on sociodemographic information and health history. Psychometric properties of the pain behavior items were examined using an item response theory framework with confirmatory factor analysis and examination of differential item functioning, internal consistency, and test information curves. Results were used along with expert consensus and alignment with the adult PROMIS pain behavior items to arrive at an 8-item pediatric pain behavior short form, and all 47 items were retained in a calibrated item bank. Confirmatory factor analysis and correlations with validated measures of pain, pain interference, and psychosocial functioning provided support for the short form's reliability and validity. The new PROMIS pediatric pain behavior scale provides a reliable, precise, and valid measure for future research on pain behavior in school-aged children with chronic pain. AD - University of Cincinnati College of Medicine, Cincinnati, OH, USA. Division of Behavioral Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. Department of Anesthesiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. Outcomes Research, Evidera, Bethesda, MD, USA. Department of Pediatrics, Emory University School of Medicine and AFLAC Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, USA. Division of Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, USA. James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. Department of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. AN - 28394851 AU - Cunningham, N. R. AU - Kashikar-Zuck, S. AU - Mara, C. AU - Goldschneider, K. R. AU - Revicki, D. A. AU - Dampier, C. AU - Sherry, D. D. AU - Crosby, L. AU - Carle, A. AU - Cook, K. F. AU - Morgan, E. M. C2 - PMC5996986 C6 - NIHMS863544 DA - Jul DO - 10.1097/j.pain.0000000000000914 DP - NLM ET - 2017/04/11 IS - 7 KW - Adolescent Anemia, Sickle Cell/*complications Arthritis, Juvenile/*complications Child Chronic Pain/*diagnosis/etiology Diagnostic Self Evaluation Female Fibromyalgia/*complications Humans Male Pain Measurement/*methods Psychometrics Reproducibility of Results Self Report Severity of Illness Index LA - eng N1 - 1872-6623 Cunningham, Natoshia R Kashikar-Zuck, Susmita Mara, Constance Goldschneider, Kenneth R Revicki, Dennis A Dampier, Carlton Sherry, David D Crosby, Lori Carle, Adam Cook, Karon F Morgan, Esi M U01 AR057929/AR/NIAMS NIH HHS/United States U01 AR052181/AR/NIAMS NIH HHS/United States U01 AR057954/AR/NIAMS NIH HHS/United States U01 AR057940/AR/NIAMS NIH HHS/United States U01 AR057948/AR/NIAMS NIH HHS/United States U01 AR057956/AR/NIAMS NIH HHS/United States U01 AR052158/AR/NIAMS NIH HHS/United States U01 AR057971/AR/NIAMS NIH HHS/United States K24 AR056687/AR/NIAMS NIH HHS/United States U01 AR057967/AR/NIAMS NIH HHS/United States U01 AR052155/AR/NIAMS NIH HHS/United States U54 AR057943/AR/NIAMS NIH HHS/United States U01 AR052171/AR/NIAMS NIH HHS/United States U01 AR057936/AR/NIAMS NIH HHS/United States U01 AR052186/AR/NIAMS NIH HHS/United States U54 AR057951/AR/NIAMS NIH HHS/United States U54 AR057926/AR/NIAMS NIH HHS/United States Journal Article Validation Study Pain. 2017 Jul;158(7):1323-1331. doi: 10.1097/j.pain.0000000000000914. PY - 2017 SN - 0304-3959 (Print) 0304-3959 SP - 1323-1331 ST - Development and validation of the self-reported PROMIS pediatric pain behavior item bank and short form scale T2 - Pain TI - Development and validation of the self-reported PROMIS pediatric pain behavior item bank and short form scale VL - 158 ID - 3131 ER - TY - JOUR AB - Chronic pain (CP) in children is a significant medical condition. The exact incidence is difficult to define but we know that historically it has been underdiagnosed and undertreated. Children can present with a variety of pain conditions (e.g. chronic headache, abdominal pain and musculoskeletal/limb pain). The medical pathway of children with chronic pain is a long and stressful one, often involving extensive investigations. A child with chronic pain will show a variety of concomitant symptoms - sleep disturbance, school absence, psychological symptoms such as anxiety, low mood and in extreme cases depression. The impact on the family needs to be taken into consideration, as by the time the child is referred to pain management there is invariably a degree of parental stress and family dysfunction. Children with chronic pain should have a full assessment of their pain and require the input of a multidisciplinary team: physicians, physiotherapists, psychologists and child and adolescent psychiatrists. Treatment goals rely on reducing or eliminating the pain, improving overall function and allowing the child to develop successful coping strategies. AN - WOS:000214197400001 AU - Cupples, P. A. DA - Dec DO - 10.1016/j.mpaic.2013.09.006 IS - 12 N1 - Cupples, Pamela A. 1878-7584 PY - 2013 SN - 1472-0299 SP - 517-519 ST - Chronic pain in children T2 - Anaesthesia and Intensive Care Medicine TI - Chronic pain in children UR - ://WOS:000214197400001 VL - 14 ID - 2336 ER - TY - JOUR AB - Improvements in hemophilia care over the last several decades might lead to expectations of a near-normal quality of life for young adults with hemophilia. However, few published reports specifically examine health status indicators in this population. To remedy this knowledge gap, we examined the impact of hemophilia on physical and social functioning and quality of life among a national US cohort of 141 young men with hemophilia aged 18-34 years of age who received care at 10 geographically diverse, federally funded hemophilia treatment centers in 11 states between 2005 and 2013 and enrolled in the Hemophilia Utilization Group Studies. Indicators studied included educational achievement, employment status, insurance, health-related quality of life, and prevalence of the following comorbidities: pain, range of motion limitation, overweight/obesity, and viral status. The cohort was analyzed to compare those aged 18-24 to those aged 25-34 years. When compared to the general US adult population, this nationally representative cohort of young US adults with hemophilia experienced significant health and social burdens: more liver disease, joint damage, joint pain, and unemployment as well as lower high-school graduation rates. Nearly half were overweight or obese. Conversely, this cohort had higher levels of health insurance and equivalent mental health scores. While attention has typically focused on newborns, children, adolescents, and increasingly, on older persons with hemophilia, our findings suggest that a specific focus on young adults is warranted to determine the most effective interventions to improve health and functioning for this apparently vulnerable age group. AD - Factor VIII Computing, Berkeley, California. The Center for Comprehensive Care & Diagnosis of Inherited Blood Disorders, Orange, CA and University of California Los Angeles, California. University of Colorado, Hemophilia and Thrombosis Center, Aurora, Colorado. Gulf States Hemophilia & Thrombophilia Center, University of Texas Health Science Center at Houston, Texas. University of Southern California, Los Angeles, California. AN - 26619192 AU - Curtis, R. AU - Baker, J. AU - Riske, B. AU - Ullman, M. AU - Niu, X. AU - Norton, K. AU - Lou, M. AU - Nichol, M. B. DA - Dec DO - 10.1002/ajh.24218 DP - NLM ET - 2015/12/01 KW - Activities of Daily Living Adolescent Adult Age Factors Arthralgia/epidemiology/psychology Chronic Pain/epidemiology/psychology Comorbidity Female Health Surveys Hemophilia A/economics/epidemiology/*psychology/therapy Humans Insurance Coverage/statistics & numerical data Liver Diseases/epidemiology Male Mental Health Overweight/epidemiology Prevalence Prospective Studies *Quality of Life Range of Motion, Articular Socioeconomic Factors Treatment Outcome United States/epidemiology Virus Diseases/epidemiology *Young Adult/psychology LA - eng N1 - 1096-8652 Curtis, Randall Baker, Judith Riske, Brenda Ullman, Megan Niu, Xiaoli Norton, Kristi Lou, Mimi Nichol, Michael B Comparative Study Journal Article Multicenter Study Research Support, Non-U.S. Gov't United States Am J Hematol. 2015 Dec;90 Suppl 2:S11-6. doi: 10.1002/ajh.24218. PY - 2015 SN - 0361-8609 SP - S11-6 ST - Young adults with hemophilia in the U.S.: demographics, comorbidities, and health status T2 - Am J Hematol TI - Young adults with hemophilia in the U.S.: demographics, comorbidities, and health status VL - 90 Suppl 2 ID - 3564 ER - TY - JOUR AB - Case 1: A 33-year-old man with hemoglobin SS (homozygous hemoglobin S) disease presents for his regular clinic visit. He had 6 hospital admissions for pain over the past year. He also has avascular necrosis of the right hip. He takes daily hydroxyurea with hematologic changes indicative of compliance. He also takes morphine sustained release twice daily and morphine immediate release every 6 hours as needed for pain. He feels that more optimal pain control at home would help him reduce his number of hospital admissions in the upcoming year and improve his daily functioning at home. His hematologist decides to use Patient-Reported Outcome Measurement Information System (PROMIS) and Adult Sickle Cell Quality of Life Measurement Information System (ASCQ-ME) to follow changes in the patient's pain. Case 2: An 11-year-old girl with hemoglobin SS disease presents with her mother for her regular clinic visit. She had 2 admissions for pain over the past year. Her mother is concerned because she has been participating less in activities she previously enjoyed and missing classes to go to the school nurse because of pain. She is currently taking hydroxyurea and uses ibuprofen for pain. Her doctor prescribes morphine for home use but wants a way to measure if it is effective in improving her pain. Thus, her physician decides to use PROMIS and the Pediatric Quality of Life Inventory SCD (PedsQL SCD) module to determine the effectiveness of her pain control. AD - Section of Medical Oncology/Hematology Yale Cancer Center, New Haven, CT. Section of Pediatric Hematology/Oncology Medical College of Wisconsin, Milwaukee, WI; and. Children's Research Institute of the Children's Hospital of Wisconsin, Milwaukee, WI. AN - 29222303 AU - Curtis, S. AU - Brandow, A. M. C2 - PMC6142574 DA - Dec 8 DO - 10.1182/asheducation-2017.1.542 DP - NLM ET - 2017/12/10 IS - 1 KW - Adult Anemia, Sickle Cell/*therapy Child Female *Health Information Systems Humans Male Morphine/administration & dosage/adverse effects *Pain Management *Pain Measurement LA - eng N1 - 1520-4383 Curtis, Susanna Brandow, Amanda M K23 HL114636/HL/NHLBI NIH HHS/United States Case Reports Journal Article Review Hematology Am Soc Hematol Educ Program. 2017 Dec 8;2017(1):542-545. doi: 10.1182/asheducation-2017.1.542. PY - 2017 SN - 1520-4391 (Print) 1520-4383 SP - 542-545 ST - Responsiveness of Patient-Reported Outcome Measurement Information System (PROMIS) pain domains and disease-specific patient-reported outcome measures in children and adults with sickle cell disease T2 - Hematology Am Soc Hematol Educ Program TI - Responsiveness of Patient-Reported Outcome Measurement Information System (PROMIS) pain domains and disease-specific patient-reported outcome measures in children and adults with sickle cell disease VL - 2017 ID - 3678 ER - TY - JOUR AB - CONTEXT: There are no studies on the effect of volunteer-provided hand massage in a busy chemotherapy outpatient practice. OBJECTIVE: To assess the feasibility of introducing hand massage therapy into an outpatient chemotherapy unit and to evaluate the effect of the therapy on various symptoms experienced by cancer patients. DESIGN: A pilot, quasi-experimental, pretest-posttest study. SETTING: Chemotherapy outpatient clinic of a large tertiary care academic medical center. PATIENTS/PARTICIPANTS: Forty chemotherapy outpatients. INTERVENTION: After being approached by a trained volunteer from a hand massage team, patients consented to receive a 20-minute hand massage before chemotherapy that was individualized according to patient preference and expressed needs. MAIN OUTCOME MEASURES: The visual analog scale (VAS) was used to measure pain, fatigue, anxiety, muscular discomfort, nervousness, stress, happiness, energy, relaxation, calmness, and emotional well-being (on a scale from 0-10) before and after the intervention; a satisfaction survey was administered after the therapy. Patients' demographic data were summarized with descriptive statistics, and VAS total scores were compared between groups at each time point with the two-group t test. Feasibility was evaluated from the number of patients who were approached, received a hand massage, and completed the study surveys. RESULTS: Of the 40 participants, 19 were men (mean age, 59.5 years). Significant improvement after hand massage was indicated by VAS scores for fatigue, anxiety, muscular discomfort, nervousness, stress, happiness, energy, relaxation, calmness, and emotional well-being (P < .05). Pain scores also improved, but the difference was not statistically significant (P = .06). All patients indicated that they would recommend hand massage to other patients, and 37 were interested in receiving it during their next chemotherapy treatment. AD - Division of General Internal Medicine, Mayo Clinic, Rochester, MN. Electronic address: cutshall.susanne@mayo.edu. Division of General Internal Medicine, Mayo Clinic, Rochester, MN. Hospital Operations, Mayo Clinic, Rochester, MN. Department of Nursing, Mayo Clinic, Rochester, MN. Department of Emergency Medicine, Mayo Clinic, Owatonna, MN. Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN. AN - 29097109 AU - Cutshall, S. M. AU - Mahapatra, S. AU - Hynes, R. S. AU - Van Rooy, K. M. AU - Looker, S. A. AU - Ghosh, A. AU - Schleck, C. D. AU - Bauer, B. A. AU - Wahner-Roedler, D. L. DA - Nov-Dec DO - 10.1016/j.explore.2017.06.007 DP - NLM ET - 2017/11/04 IS - 6 KW - Adolescent Adult Aged *Ambulatory Care Anxiety/etiology/therapy Emotions Fatigue/etiology/therapy Feasibility Studies Female *Hand Humans Male *Massage Middle Aged Muscles *Neoplasms/complications/drug therapy/psychology Pain Management *Patient Satisfaction Pilot Projects Relaxation Stress, Psychological/etiology/therapy Surveys and Questionnaires Young Adult Cancer Chemotherapy Hand massage Volunteers LA - eng N1 - 1878-7541 Cutshall, Susanne M Mahapatra, Saswati Hynes, Rebecca S Van Rooy, Kimberly M Looker, Sherry A Ghosh, Aditya Schleck, Cathy D Bauer, Brent A Wahner-Roedler, Dietlind L Journal Article United States Explore (NY). 2017 Nov-Dec;13(6):393-399. doi: 10.1016/j.explore.2017.06.007. Epub 2017 Aug 25. PY - 2017 SN - 1550-8307 SP - 393-399 ST - Hand Massage for Cancer Patients Undergoing Chemotherapy as Outpatients: A Pilot Study T2 - Explore (NY) TI - Hand Massage for Cancer Patients Undergoing Chemotherapy as Outpatients: A Pilot Study VL - 13 ID - 3823 ER - TY - JOUR AB - Chronic daily headache (CDH) affects 2 to 4% of adolescent females and 0.8 to 2% of adolescent males. Chronic daily headache is diagnosed when headaches occur more than 4 hours a day, for greater than or equal to 15 headache days per month, over a period of 3 consecutive months, without an underlying pathology. It is manifested by severe intermittent headaches, that are migraine-like, as well as a chronic baseline headache. Silberstein and Lipton divided patients into four diagnostic categories: transformed migraine, chronic tension-type headache, new daily-persistent headache, and hemicrania continua. The second edition of the International Classification of Headache Disorders did not comprise any CDH category as such, but provided criteria for all four types of CDH: chronic migraine, chronic tension- type headache, new daily-persistent headache, and hemicrania continua. The International Headache Society. Children and adolescents with chronic daily headache frequently have sleep disturbance, pain at other sites, dizziness, medication-overuse headache and a psychiatric comorbidity (anxiety and mood disorders). Chronic daily headache frequently results in school absence. Successful approaches to treatment include reassurance, education, use of preventative medication, avoidance of analgesics, and helping the child work its way back into a functional daily routine and a regular school schedule. AN - WOS:000433875100003 AU - Cuvellier, J. C. DO - 10.2174/157339608787407636 IS - 4 N1 - Cuvellier, Jean-Christophe 1875-6336 PY - 2008 SN - 1573-3963 SP - 233-242 ST - Pediatric Chronic Daily Headache T2 - Current Pediatric Reviews TI - Pediatric Chronic Daily Headache UR - ://WOS:000433875100003 VL - 4 ID - 2667 ER - TY - JOUR AB - Chronic daily headache (CDH) affects 2-4% of adolescent females and 0.8-2% of adolescent males. Chronic daily headache is diagnosed when headaches occur more than 4 h/day, 15 headache days per month or more, over a period of 3 consecutive months, without an underlying pathology. It is manifested by severe intermittent, migraine-like headaches as well as by chronic baseline headaches. Both Silberstein-Lipton criteria and the second edition of the International Classification of Headache Disorders (ICHD) can be used to classify chronic daily headache in children and adolescents. Chronic daily headache is' classified into four diagnostic categories: transformed (Silberstein-Lipton criteria)/chronic (ICHD) migraine, chronic tension-type headache, new daily persistent headache, and hemicrania continua. Children and adolescents with chronic daily headache frequently have sleep disturbance, pain at other sites, dizziness, medication-overuse headache, and a psychiatric comorbidity (anxiety and mood disorders). Chronic daily headache frequently results in school absence. Successful approaches to treatment include reassurance, education, use of preventative medication, avoidance of analgesics; and helping the child return to a functional daily routine and a regular school schedule. (C) 2008 Elsevier Masson SAS. All rights reserved. AN - WOS:000261772400012 AU - Cuvellier, J. C. AU - Cuisset, J. M. AU - Vallee, L. DA - Dec DO - 10.1016/j.arcped.2008.09.017 IS - 12 N1 - Cuvellier, J. -C. Cuisset, J. -M. Vallee, L. 1769-664x PY - 2008 SN - 0929-693X SP - 1805-1814 ST - Chronic daily headache in children and adolescents T2 - Archives De Pediatrie TI - Chronic daily headache in children and adolescents UR - ://WOS:000261772400012 VL - 15 ID - 2630 ER - TY - JOUR AB - BACKGROUND: Isotretinoin, for acne treatment, is associated with high rates of permanent remission. However, at recommended doses of 0.5-1.0 mg/kg/day for 5-6 months [average cumulative dose: 120-150 mg/kg], more than 20% of patients experience a relapse within two years that requires further medical management. OBJECTIVE: To examine outcomes of high-dose isotretinoin in a cohort with cystic acne, as well as measuring its impact on quality of life (QOL). METHODS: A single dermatologist, single institution investigation within an academic tertiary care center in Bronx, NY. Eighty patients with nodulocystic acne, maintained on oral isotretinoin at a dose of 1.3 mg/kg/day or greater, were studied from 2006-2009 while additionally participating in a QOL survey. Main outcome measures included documented events, acne clearance, presence of relapse, and quality of life parameters. RESULTS: The mean daily dose of isotretinoin was 1.6 mg/kg/day for an average time course of 178 days [cumulative dose: 290 mg/kg]. No side effects or laboratory abnormalities led to discontinuation of treatment. There were no psychiatric symptoms. One-hundred percent (100%) of patients were disease-free upon completion of treatment. During the three-year study period, 10 patients (12.5%) developed a relapse that required an additional course of isotretinoin. Analysis of QOL domains (self-perception, role-social, symptoms) revealed significant improvement following isotretinoin therapy (p = 0.0124, p = 0.0066, p = 0.0265, respectively). CONCLUSIONS: Isotretinoin prescribed at 1.5 mg/kg/day or greater for 5-6 months [cumulative total dose of 290 mg/kg] is safe and effective compared to current standard dosing practices. We propose the use of high-dose isotretinoin (>1.3 mg/kg/day) as a treatment option in severe nodulocystic acne and encourage larger, prospective, multicenter studies into this therapeutic approach. AD - Department of Dermatology, Albert Einstein College of Medicine, New York, NY 10467, USA. AN - 22909370 AU - Cyrulnik, A. A. AU - Viola, K. V. AU - Gewirtzman, A. J. AU - Cohen, S. R. DA - Sep DO - 10.1111/j.1365-4632.2011.05409.x DP - NLM ET - 2012/08/23 IS - 9 KW - Acne Vulgaris/*drug therapy/psychology Adolescent Adult Child Dermatologic Agents/*administration & dosage/adverse effects Female Headache/chemically induced Health Surveys Humans Isotretinoin/*administration & dosage/adverse effects Liver Function Tests Male Middle Aged Musculoskeletal Pain/chemically induced Quality of Life/*psychology Recurrence Retrospective Studies Self Concept Surveys and Questionnaires Treatment Outcome Young Adult LA - eng N1 - 1365-4632 Cyrulnik, Amanda A Viola, Kate V Gewirtzman, Aron J Cohen, Steven R Journal Article England Int J Dermatol. 2012 Sep;51(9):1123-30. doi: 10.1111/j.1365-4632.2011.05409.x. PY - 2012 SN - 0011-9059 SP - 1123-30 ST - High-dose isotretinoin in acne vulgaris: improved treatment outcomes and quality of life T2 - Int J Dermatol TI - High-dose isotretinoin in acne vulgaris: improved treatment outcomes and quality of life VL - 51 ID - 3367 ER - TY - JOUR AB - Purpose: The specific assessment of pain and quality of life in children with sickle cell anemia (SCA) is still the subject of few studies and is traditionally evaluated through perception of their parents or guardians. Thus, this study aimed to evaluate pain, its characteristics, and impact on the quality of life (QoL) in children diagnosed with SCA, valuing their self-report. Patients and Methods: This study was conducted on hematology and hemotherapy outpatient clinic in Sao Luis, Brazil, with children between 7 years and 12 years with SCA, of both genders. The instruments used were Numeric Pain Rating Scale, Faces Pain Scale and Autoquestionnaire Qualite de Vie Enfante Image (AUQEI) for the assessment of pain and QoL from the children's self-report. The association between pain intensity and QoL was verified through the Chi-square test and the relationship between pain and the domains of AUQEI was verified through Pearson's correlation, using Stata 10.0 (R). Results: The sample consisted of 104 children with a mean age of 8.97 years, 51.9% were male and 94.2% non-white. Pain was characterized predominately moderate to strong, stabbing (37.5%) and burning (31.7%), with greater frequency in the limbs, and reported simultaneously in two or more locations. The average pain score was 9.26 at the worst time and in the general context was 6.02. As a result of pain, 93.3% reported school absence, averaging 8.57 days of absence; 63.5% had sleep disturbance and 86.5% failed to perform your daily activities. QoL results were negative in 48.08% and 56.25% of these had severe pain. About 74% of children with positive QoL had mild pain. Conclusion: Pain in children with SCA has a negative impact on their QoL based on their point of view, affecting their daily life. These findings highlight the importance of valuing children's self-report of the disease, especially in a restricted resource scenario. AN - WOS:000600938800001 AU - da Cunha, V. B. AU - Rodrigues, C. F. D. AU - Rodrigues, T. A. AU - de Oliveira, Ejsg AU - Garcia, J. B. S. DO - 10.2147/jpr.S261605 N1 - da Cunha, Valeska Brito de Andrade Rodrigues, Camila Freitas Rodrigues, Thiago Alves Silva Gomes de Oliveira, Eduardo Jose Santos Garcia, Joao Batista PY - 2020 SN - 1178-7090 SP - 3171-3180 ST - Self-Report for Assessment of Pain and Quality of Life in Children with Sickle Cell Anemia in a Developing Country T2 - Journal of Pain Research TI - Self-Report for Assessment of Pain and Quality of Life in Children with Sickle Cell Anemia in a Developing Country UR - ://WOS:000600938800001 VL - 13 ID - 1852 ER - TY - JOUR AB - Background Research among adult and paediatric samples suggests that pain-related injustice appraisals contribute to adverse pain-related functioning. However, a singular focus on pain-related injustice appraisals carries the risk of underestimating the role of broader concepts of justice. This study examined the unique roles of child pain-related injustice appraisals and just-world beliefs in understanding disability and physical, emotional, social and academic functioning, as well as the mediating role of injustice appraisals in the relationship between just-world beliefs and functioning. Methods Participants comprised a school sample of 2,174 children (Study 1) and a clinical sample of 146 paediatric chronic pain patients (Study 2) who completed the Injustice Experience Questionnaire (IEQ), Personal and General Belief in a Just World scales (JWB-P/G), Functional Disability Inventory (FDI), Pain Catastrophizing Scale for Children (PCS-C) and Pediatric Quality of Life Inventory (PEDSQL). Results For both samples, child pain-related injustice appraisals were associated with poorer functioning, after controlling for just-world beliefs, catastrophizing, pain intensity, age and sex. In the school sample, injustice appraisals mediated the associations of both personal and general just-world beliefs with functioning. In the clinical sample, injustice appraisals mediated the association of personal, but not general, just-world beliefs with all functioning scales. Conclusions The current findings attest to the unique role of pain-related injustice appraisals in understanding child pain-related functioning and their explanatory value in understanding the relationship between fundamental just-world beliefs and child pain-related functioning. Significance The present study adds to emerging literature on the adverse effects of child pain-related injustice appraisals in the context of pain, through showing that pain-related injustice appraisals are uniquely associated with pain-related functioning and mediate the relationship between just-world beliefs and pain-related functioning. These findings suggest that interventions may target pain-related injustice appraisals as a mechanism for change in children. AN - WOS:000597553900001 AU - Daenen, F. AU - McParland, J. AU - Baert, F. AU - Miller, M. M. AU - Hirsh, A. T. AU - Vervoort, T. DO - 10.1002/ejp.1707 N1 - Daenen, Frederick McParland, Joanna Baert, Fleur Miller, Megan Marie Hirsh, Adam Todd Vervoort, Tine Daenen, Frederick/0000-0002-0657-5468; McParland, Jo/0000-0003-0580-2179 1532-2149 SN - 1090-3801 ST - Child pain-related injustice appraisals mediate the relationship between just-world beliefs and pain-related functioning T2 - European Journal of Pain TI - Child pain-related injustice appraisals mediate the relationship between just-world beliefs and pain-related functioning UR - ://WOS:000597553900001 ID - 1779 ER - TY - JOUR AB - BACKGROUND: Research among adult and paediatric samples suggests that pain-related injustice appraisals contribute to adverse pain-related functioning. However, a singular focus on pain-related injustice appraisals carries the risk of underestimating the role of broader concepts of justice. This study examined the unique roles of child pain-related injustice appraisals and just-world beliefs in understanding disability and physical, emotional, social and academic functioning, as well as the mediating role of injustice appraisals in the relationship between just-world beliefs and functioning. METHODS: Participants comprised a school sample of 2,174 children (Study 1) and a clinical sample of 146 paediatric chronic pain patients (Study 2) who completed the Injustice Experience Questionnaire (IEQ), Personal and General Belief in a Just World scales (JWB-P/G), Functional Disability Inventory (FDI), Pain Catastrophizing Scale for Children (PCS-C) and Pediatric Quality of Life Inventory (PEDSQL). RESULTS: For both samples, child pain-related injustice appraisals were associated with poorer functioning, after controlling for just-world beliefs, catastrophizing, pain intensity, age and sex. In the school sample, injustice appraisals mediated the associations of both personal and general just-world beliefs with functioning. In the clinical sample, injustice appraisals mediated the association of personal, but not general, just-world beliefs with all functioning scales. CONCLUSIONS: The current findings attest to the unique role of pain-related injustice appraisals in understanding child pain-related functioning and their explanatory value in understanding the relationship between fundamental just-world beliefs and child pain-related functioning. SIGNIFICANCE: The present study adds to emerging literature on the adverse effects of child pain-related injustice appraisals in the context of pain, through showing that pain-related injustice appraisals are uniquely associated with pain-related functioning and mediate the relationship between just-world beliefs and pain-related functioning. These findings suggest that interventions may target pain-related injustice appraisals as a mechanism for change in children. AD - Department of Experimental-Clinical and Health Psychology, Ghent University, Ghent, Belgium. Department of Psychology, Glasgow Caledonian University, Glasgow, UK. Department of Psychology, Indiana University-Purdue University Indianapolis, Indianapolis, IN, USA. AN - 33259693 AU - Daenen, F. AU - McParland, J. AU - Baert, F. AU - Miller, M. M. AU - Hirsh, A. T. AU - Vervoort, T. DA - Apr DO - 10.1002/ejp.1707 DP - NLM ET - 2020/12/02 IS - 4 KW - Adult Catastrophization Child *Chronic Pain Humans Pain Measurement Pain Perception *Quality of Life Surveys and Questionnaires LA - eng N1 - 1532-2149 Daenen, Frederick McParland, Joanna Baert, Fleur Miller, Megan Marie Hirsh, Adam Todd Vervoort, Tine Journal Article Research Support, Non-U.S. Gov't England Eur J Pain. 2021 Apr;25(4):757-773. doi: 10.1002/ejp.1707. Epub 2020 Dec 11. PY - 2021 SN - 1090-3801 SP - 757-773 ST - Child pain-related injustice appraisals mediate the relationship between just-world beliefs and pain-related functioning T2 - Eur J Pain TI - Child pain-related injustice appraisals mediate the relationship between just-world beliefs and pain-related functioning VL - 25 ID - 3002 ER - TY - JOUR AB - Juvenile fibromyalgia (JFM) is a chronic and debilitating noninflammatory musculoskeletal pain syndrome that is typically diagnosed in adolescence. There are no specific medical tests or disease markers to diagnose the condition, and classification is based on patient report of pain and other associated symptoms after ruling out other underlying medical causes. JFM can be disabling in multiple life domains and therefore, a multidimensional assessment of JFM is recommended to gain a full picture of the extent of JFM symptoms along with their impact on physical and emotional functioning and quality of life. The following updated review outlines evidence-based measures useful in the assessment of school-age children and adolescents with JFM. New measures include 1) the Pain and Symptom Assessment Tool (PSAT) that offers a standardized tool for the classification of fibromyalgia in pediatric patients and 2) the Patient-Reported Outcomes Measurement Information System (PROMIS®) Pediatric Pain Interference, Anxiety, and Depression Scales. Updated information is presented on previously established measures that assess the impact of JFM on functioning and quality of life - the Functional Disability Inventory (FDI) and the Pediatric Quality of Life Inventory (PedsQL) 3.0 Rheumatology Module Pain and Hurt Scale, are also discussed. In general, there are increasing options for validated patient-reported outcome measures available to measure the spectrum of symptoms in JFM and assess impact on daily life. Greater consistency in identification of JFM and use of standardized assessment tools will undoubtedly lead to higher quality research much needed in this relatively understudied musculoskeletal pain condition. AD - Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio. University of Cincinnati, Cincinnati, Ohio. AN - 33091238 AU - Daffin, M. AU - Gibler, R. C. AU - Kashikar-Zuck, S. C2 - PMC7647372 C6 - NIHMS1589500 interest. R.C. Gibler declares that he has no conflict of interest. S. Kashikar-Zuck declares that she has no conflict of interest. DA - Oct DO - 10.1002/acr.24197 DP - NLM ET - 2020/10/23 IS - Suppl 10 KW - Adolescent Child *Fibromyalgia Humans *Outcome Assessment, Health Care Psychometrics/instrumentation Severity of Illness Index LA - eng N1 - 2151-4658 Daffin, Morgan Gibler, Robert C Kashikar-Zuck, Susmita K24 AR056687/AR/NIAMS NIH HHS/United States Journal Article Review Arthritis Care Res (Hoboken). 2020 Oct;72 Suppl 10(Suppl 10):171-182. doi: 10.1002/acr.24197. PY - 2020 SN - 2151-464X (Print) 2151-464x SP - 171-182 ST - Measures of Juvenile Fibromyalgia T2 - Arthritis Care Res (Hoboken) TI - Measures of Juvenile Fibromyalgia VL - 72 Suppl 10 ID - 2985 ER - TY - JOUR AB - BACKGROUND: Children dental pain recognition is pointed as a priority in paediatric dentistry, but little is known about dentists' perception of pre-schoolers' dental pain. AIM: To understand paediatric dentists' viewpoint on dental pain (toothache) in pre-schoolers and to identify the associated factors. DESIGN: Mixed-methods with two phases: (i) preliminary qualitative study (focus group of paediatric dentists), with responses analysed by content analysis and (ii) quantitative survey (self-administered questionnaire answered by 223 paediatric dentists), with the main outcome 'perception' assessed as 'feel or not prepared' to identify a pre-schooler with dental pain. Triangulation was used to discuss the results of each approach. RESULTS: (i) Paediatric dentists can observe dental pain in pre-schoolers when there are normative signs; this pain is related to the changes in a child's behaviour and in dental planning. (ii) Participants were 40.1 ± 8.4 years old, 17.1 ± 8.3years since graduation, 65.9% did not feel prepared to identify a pre-schooler with dental pain. This feeling of unpreparedness was associated with younger specialists (P = 0.01) and less time since graduation (P < 0.01). Triangulation showed a convergence of the qualitative and quantitative approaches. CONCLUSION: Noticing dental pain in pre-schoolers was associated with specialists' experience and the need for visible signs; dentists do not always feel completely prepared to recognise pain in pre-schoolers. AD - Health Sciences Graduate Program, Federal University of Goias (UFG), Goiania, Brazil. AN - 24612101 AU - Daher, A. AU - Costa, M. AU - Costa, L. R. DA - Jan DO - 10.1111/ipd.12099 DP - NLM ET - 2014/03/13 IS - 1 KW - Adult *Attitude of Health Personnel Child, Preschool Dental Care for Children *Dentist-Patient Relations Dentists/*psychology Female Focus Groups Humans Male *Pain Management *Pain Measurement Surveys and Questionnaires *Toothache LA - eng N1 - 1365-263x Daher, Anelise Costa, Márcia Costa, Luciane R Journal Article Research Support, Non-U.S. Gov't England Int J Paediatr Dent. 2015 Jan;25(1):51-60. doi: 10.1111/ipd.12099. Epub 2014 Feb 24. PY - 2015 SN - 0960-7439 SP - 51-60 ST - Factors associated with paediatric dentists' perception of dental pain in pre-schoolers: a mixed-methods study T2 - Int J Paediatr Dent TI - Factors associated with paediatric dentists' perception of dental pain in pre-schoolers: a mixed-methods study VL - 25 ID - 3739 ER - TY - JOUR AB - Objectives: To develop a profile of impairment and activity limitation among children with epiphyseal dysplasia (ED) and to identify the relationship between these 2 domains. Design: Cross-sectional study. Setting: Acute, pediatric academic and health sciences center. Participants: Eleven subjects with multiple epiphyseal dysplasia (MED) and 17 subjects with spondyloepiphyseal dysplasia (SED), with a mean age of 12.9 years. Interventions: Not applicable. Main Outcome Measures: Anthropometric indexes of growth and nutrition, joint range of motion (ROM) and alignment, muscle strength, pain, and activity limitation. Results: Subjects with SED had significantly shorter stature than the reference population (P<.01). Seventy-three percent of participants with MED and 77% of those with SED were above average or overweight for their height (P<.01). Both groups presented with moderate to severe joint ROM impairment, with greater lower-extremity involvement. Subjects with SED had worse outcomes with respect to overall ROM and alignment impairments (P<.01), particularly in their upper extremities (P<.01), than subjects with MED. Significant overall muscle weakness was noted in all subjects (z=-1.81; P<.01). Ninety-four percent of subjects with SED reported pain with activity, compared with 64% of those with MED (P=.04), although pain intensity did not differ between groups. Fifty percent of subjects had undergone orthopedic surgery. Mild activity limitation was reported by all subjects (mean score, 87.7+/-18.83). Significant correlations were identified between height for age and strength (r=.50) and pain and activity limitation (r=-.50). Conclusions: Despite moderate to severe impairments, all subjects reported surprisingly mild activity limitation. A positive correlation was identified between pain and activity limitation. This study also identified and described patterns of muscle weakness, pain, and nutritional concerns not previously reported in the ED literature. (C) 2004 by the American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation. AN - WOS:000224404700013 AU - Damignani, R. AU - Young, N. L. AU - Cole, W. G. AU - Anthony, A. M. AU - Badley, E. M. DA - Oct DO - 10.1016/j.apmr.2003.12.030 IS - 10 N1 - Damignani, R Young, NL Cole, WG Anthony, AM Badley, EM 5th Interdisciplinary Paediatric Orthopaedic Conference Apr 12, 2002 Montreal, CANADA ; Young, Nancy/G-3934-2011 Anthony, Alison/0000-0002-6085-699X; Young, Nancy/0000-0002-1739-3299 1532-821x PY - 2004 SN - 0003-9993 SP - 1647-1652 ST - Impairment and activity limitation associated with epiphyseal dysplasia in children T2 - Archives of Physical Medicine and Rehabilitation TI - Impairment and activity limitation associated with epiphyseal dysplasia in children UR - ://WOS:000224404700013 VL - 85 ID - 2783 ER - TY - JOUR AB - PURPOSE: To determine the incidence of pain and the types of home pain management techniques used by children and adolescents with sickle cell disease (SCD) and their caregivers. PATIENTS AND METHODS: Thirty-seven children and adolescents (ages 6-21 years) with SCD used a self-report pain diary twice daily to report their pain experience and its management for 6 months to 3 years. A total of 18,377 diary days representing 514 distinct pain episodes were analyzed. RESULTS: Pain related to SCD was reported on 2592 days and 2326 nights, with analgesic medication taken on 88% of days and 76% of nights. A single oral analgesic was used on 58% of these days. On the remaining days, multiple analgesics were used in a variety of combinations. More frequent analgesic dosing was reported on days with more intense pain. Pain relief was substantially better for analgesic combinations than for single analgesics, particularly for moderate to severe pain. CONCLUSIONS: Pain went untreated on a modest number of days, and many patients relied on relatively ineffective single analgesics. Other patients and families appropriately used potent analgesic combinations in a time-contingent and intensity-dependent pattern. This study suggests that recurrent acute pain from SCD can be successfully managed at home with appropriate training and supervision, and suggests several areas for intervention to improve patient outcomes. AD - Marian Anderson Comprehensive Sickle Cell Center, St. Christopher's Hospital for Children, Erie Avenue at Front Street, Philadelphia, PA 19134-1095, USA. Carlton.Dampier@drexel.edu AN - 12439036 AU - Dampier, C. AU - Ely, E. AU - Brodecki, D. AU - O'Neal, P. DA - Nov DO - 10.1097/00043426-200211000-00008 DP - NLM ET - 2002/11/20 IS - 8 KW - Absenteeism Adolescent Adult Analgesics, Non-Narcotic/administration & dosage/therapeutic use Anemia, Sickle Cell/*complications/therapy Biomarkers Child Child, Preschool Drug Administration Schedule Drug Therapy, Combination Female Home Nursing Humans Hydroxyurea/therapeutic use Longitudinal Studies Male *Medical Records Narcotics/administration & dosage/therapeutic use Pain/*epidemiology/etiology Pain Management Pain Measurement Quality of Life Reproducibility of Results Sickle Cell Trait/complications LA - eng N1 - Dampier, Carlton Ely, Elizabeth Brodecki, Darcy O'Neal, Patricia HL 51496/HL/NHLBI NIH HHS/United States HL 51495/HL/NHLBI NIH HHS/United States P60 HL 62148/HL/NHLBI NIH HHS/United States HL 51497/HL/NHLBI NIH HHS/United States Journal Article Research Support, U.S. Gov't, P.H.S. United States J Pediatr Hematol Oncol. 2002 Nov;24(8):643-7. doi: 10.1097/00043426-200211000-00008. PY - 2002 SN - 1077-4114 (Print) 1077-4114 SP - 643-7 ST - Home management of pain in sickle cell disease: a daily diary study in children and adolescents T2 - J Pediatr Hematol Oncol TI - Home management of pain in sickle cell disease: a daily diary study in children and adolescents VL - 24 ID - 3516 ER - TY - JOUR AB - Background The hallmark of sickle cell disease (SCD) is pain from a vaso-occlusive crisis. Although ambulatory pain accounts for most days in pain, pain is also the most common cause of hospitalization and is typically treated with parenteral opioids. The evidence base is lacking for most analgesic practice in SCD, particularly for the optimal opioid dosing for patient-controlled analgesia (PCA), in part because of the challenges of the trial design and conduct for this rare disease. Purpose The purpose of this report is to describe our Network's experiences with protocol development, implementation, and analysis, including overall study design, the value of pain assessments rather than 'crisis' resolution as trial endpoints, and alternative statistical analysis strategies. Methods The Improving Pain Management and Outcomes with Various Strategies (IMPROVE) PCA trial was a multisite inpatient randomized controlled trial comparing two PCA-dosing strategies in adults and children with SCD and acute pain conducted by the SCD Clinical Research Network. The specified primary endpoint was a 25-mm change in a daily average pain intensity using a Visual Analogue Scale, and a number of related pain intensity and pain interference measures were selected as secondary efficacy outcomes. A time-to-event analysis strategy was planned for the primary endpoint. Results 01 1116 individuals admitted for pain at 31 participating sites over a 6-month period, 38 were randomized and 4 withdrawn. The trial was closed early due to poor accrual, reflecting a substantial number of challenges encountered during trial implementation. Limitations While some of the design issues were unique to SCD or analgesic studies, many of the trial implementation challenges reflected the increasing complexity of conducting clinical trials in the inpatient setting with multiple care providers and evolving electronic medical record systems, particularly in the context of large urban academic medical centers. Lessons learned Complicated clinical organization of many sites likely slowed study initiation. More extensive involvement of research staff and site principal investigator in the clinical care operations improved site performance. During the subsequent data analysis, alternative statistical approaches were considered, the results of which should inform future efficacy assessments and increase future trial recruitment success by allowing substantial reductions in target sample size. Conclusions A complex randomized analgesic trial was initiated within a multisite disease network seeking to provide an evidence base for clinical care. A number of design considerations were shown to be feasible in this setting, and several pain intensity and pain interference measures were shown to be sensitive to time- and treatment-related improvements. While the premature closure and small sample size precluded definitive conclusions regarding treatment efficacy, this trial furnishes a template for design and implementation considerations that should improve future SCD analgesic trials. Clinical Trials 2013; 10: 319-331. http://ctj.sagepub.com AN - WOS:000318263300013 AU - Dampier, C. D. AU - Smith, W. R. AU - Wager, C. G. AU - Kim, H. Y. AU - Bell, M. C. AU - Miller, S. T. AU - Weiner, D. L. AU - Minniti, C. P. AU - Krishnamurti, L. AU - Ataga, K. I. AU - Eckman, J. R. AU - Hsu, L. L. AU - McClish, D. AU - McKinlay, S. M. AU - Molokie, R. AU - Osunkwo, I. AU - Smith-Whitley, K. AU - Telen, M. J. AU - Scdcrn DA - Apr DO - 10.1177/1740774513475850 IS - 2 N1 - Dampier, Carlton D. Smith, Wally R. Wager, Carrie G. Kim, Hae-Young Bell, Margaret C. Miller, Scott T. Weiner, Debra L. Minniti, Caterina P. Krishnamurti, Lakshmanan Ataga, Kenneth I. Eckman, James R. Hsu, Lewis L. McClish, Donna McKinlay, Sonja M. Molokie, Robert Osunkwo, Ifeyinwa Smith-Whitley, Kim Telen, Marilyn J. Osunkwo, Ifeyinwa/AAT-9315-2020; Dampier, Carlton/Q-2967-2019; Hsu, Lewis L/H-8001-2019 Dampier, Carlton/0000-0002-7738-2620; Telen, Marilyn/0000-0003-3809-1780; Hsu, Lewis/0000-0002-3156-2378 1740-7753 PY - 2013 SN - 1740-7745 SP - 319-331 ST - IMPROVE trial: A randomized controlled trial of patient-controlled analgesia for sickle cell painful episodes: rationale, design challenges, initial experience, and recommendations for future studies T2 - Clinical Trials TI - IMPROVE trial: A randomized controlled trial of patient-controlled analgesia for sickle cell painful episodes: rationale, design challenges, initial experience, and recommendations for future studies UR - ://WOS:000318263300013 VL - 10 ID - 2372 ER - TY - JOUR AB - BACKGROUND: Acute pain in hospitalized pediatric patients is prevalent. Recent shifts in the paradigm of pediatric acute pain management focus less on reliance on opioids, due to their adverse side effects and risk of dependence, and more on multimodal pain management. OBJECTIVE: We sought to review the most recent studies on acute pain management in hospitalized pediatric patients. METHOD: We searched the Cochrane Database and PubMed for articles published in the past five years regarding the treatment of acute pain in pediatric patients focusing on large randomized or quasirandomized controlled trials, cohort trials, and meta-analyses. RESULTS: We categorized results into non-pharmacological, localized, non-opiate pharmacological, and opiate based therapies. Recent studies show that environmental and non-pharmacological methods of pain management are efficacious in infants. School aged children benefit from active distraction more than passive distraction. Needleless methods of introducing lidocaine locally alleviate the pain associated with many procedures to which hospitalized children are exposed. The shift towards use of nonopiate pharmacology focuses on novel means of utilizing older medications, such as intravenous parecoxib, inhaled methoxyflurane, and sublingual ketorolac or tramadol and the avoidance of codeine. CONCLUSION: Acute pediatric pain management has changed to emphasize multimodal and multidisciplinary therapy. In all children, non-pharmacological therapies should be employed routinely. Given the myriad tools available, pediatric acute pain services have developed in order to integrate more advanced treatments such as nerve blocks and infusions of centrally acting pain modulators. AD - Department of Medicine and Pediatrics, University of North Carolina, 101 Manning Drive, Campus Box 7085, Chapel Hill, NC, 27599-7085. United States. Department of Internal Medicine and Pediatrics, University of North Carolina, Chapel Hill, NC. United States. Department of Pediatrics, University of California, San Francisco, CA. United States. AN - 28814263 AU - Dancel, R. AU - Liles, E. A. AU - Fiore, D. DO - 10.2174/1574887112666170816151232 DP - NLM ET - 2017/08/18 IS - 4 KW - Acute Pain/*therapy Child Humans *Inpatients Pain Management/*methods *Acute pain *analgesia *hospital *meta-analyses *multi-modal treatment *pediatric LA - eng N1 - 1876-1038 Dancel, Ria Liles, Edmund Allen Fiore, Darren Journal Article Review United Arab Emirates Rev Recent Clin Trials. 2017;12(4):277-283. doi: 10.2174/1574887112666170816151232. PY - 2017 SN - 1574-8871 SP - 277-283 ST - Acute Pain Management in Hospitalized Children T2 - Rev Recent Clin Trials TI - Acute Pain Management in Hospitalized Children VL - 12 ID - 2962 ER - TY - JOUR AB - ObjectiveaEuro integral Tested a family-based group problem-solving intervention, "Families Taking Control," (FTC) to improve school functioning and health-related quality of life (HRQL) for children with sickle cell disease.aEuro integral MethodaEuro integral Children and caregivers completed questionnaires assessing HRQL and school functioning and children completed performance-based measures of IQ and achievement at baseline and 6 months later. Families were randomized to the intervention (FTC, n = 42) or delayed intervention control (DIC, n = 41) group. FTC involved a full-day workshop followed by 3 booster calls.aEuro integral ResultsaEuro integral There were no differences between FTC completers (n = 24) and noncompleters (n = 18). FTC group (n = 24) and DIC group (n = 38) did not differ significantly on primary outcomes at follow-up: number of formal academic and disease-related accommodations, individualized education plan/504 service plan, school absences, school HRQL, or academic skills.aEuro integral ConclusionsaEuro integral Although families found FTC to be acceptable, there were no intervention effects. Challenges of the trial and implications for future research are discussed. AN - WOS:000364771600011 AU - Daniel, L. C. AU - Li, Y. M. AU - Smith, K. AU - Tarazi, R. AU - Robinson, M. R. AU - Patterson, C. A. AU - Smith-Whitley, K. AU - Stuart, M. AU - Barakat, L. P. DA - Nov-Dec DO - 10.1093/jpepsy/jsv063 IS - 10 N1 - Daniel, Lauren C. Li, Yimei Smith, Kelsey Tarazi, Reem Robinson, M. Renee Patterson, Chavis A. Smith-Whitley, Kim Stuart, Marie Barakat, Lamia P. Daniel, Lauren/AAA-3700-2021 Daniel, Lauren/0000-0002-8637-2424 1465-735x PY - 2015 SN - 0146-8693 SP - 1085-1094 ST - Lessons Learned From a Randomized Controlled Trial of a Family-Based Intervention to Promote School Functioning for School-Age Children With Sickle Cell Disease T2 - Journal of Pediatric Psychology TI - Lessons Learned From a Randomized Controlled Trial of a Family-Based Intervention to Promote School Functioning for School-Age Children With Sickle Cell Disease UR - ://WOS:000364771600011 VL - 40 ID - 2214 ER - TY - JOUR AB - A 10-year-old male patient with homozygous sickle cell disease presents for a follow-up clinic visit after a recent hospitalization for a painful vasoocclusive event. His parents mention that in the past year he has had 4 hospitalizations for vasoocclusive events, 2 of which were complicated by the development of acute chest syndrome that resulted in transfer to the intensive care unit. He has missed many school days and may be retained a grade this year. He feels particularly sad about missing the school field trip that occurred during his last hospitalization. He also reports that he is not able to keep up with his friends when participating in physical activities at school. The child's parents are worried that he may be depressed. You as the provider discuss the option of hydroxyurea therapy. His parents ask if hydroxyurea would improve his overall well-being and functioning. AN - WOS:000323755900042 AU - Darbari, D. S. AU - Panepinto, J. A. DA - Dec DO - 10.1182/asheducation-2012.1.290 N1 - Darbari, Deepika S. Panepinto, Julie A. 1520-4383 PY - 2012 SN - 1520-4391 SP - 290-291 ST - What is the evidence that hydroxyurea improves health-related quality of life in patients with sickle cell disease? T2 - Hematology-American Society of Hematology Education Program TI - What is the evidence that hydroxyurea improves health-related quality of life in patients with sickle cell disease? UR - ://WOS:000323755900042 ID - 2404 ER - TY - JOUR AB - Purpose. Although more than 125 million North Americans have one or more chronic conditions, medical training may not adequately prepare physicians to care for them. The authors evaluated physicians' perceptions of the adequacy of their chronic illness care training to and the effects of training on their attitudes toward care of persons with chronic conditions. Method. In November 2000 through June 2001, the authors surveyed by telephone a random sample of U.S. physicians who had greater than or equal to20 hours of patient contact per week. The interview instrument examined demographics, career satisfaction, practice characteristics, perceived adequacy of chronic illness care training in ten competencies (geriatric syndromes, chronic pain, nutrition, developmental milestones, end-of-life care, psychosocial issues, patient education, assessment of caregiver needs, coordination of services, and interdisciplinary teamwork), and effect of training on attitudes toward chronic illness care. Results. Of 1,905 eligible physicians, 1,236 (65%) responded (270 family or general practitioners, 231 internists, 129 pediatricians, 335 nonsurgical specialists, and 271 surgeons). Most physicians reported their chronic disease training was less than adequate for all ten competencies. Family practitioners were more likely (p < .05) to report adequate training in seven competencies compared with internists, and in two to four competencies when compared with pediatricians, nonsurgical specialists, or surgeons. Most physicians reported that training had a positive effect on attitudes toward care of people with chronic conditions, including the ability to make a difference in their lives (74-84%). Conclusions. Physicians perceived their medical training for chronic illness care was inadequate. Medical schools and residencies may need to modify curricula to better prepare physicians to treat the growing number of people with chronic conditions. AN - WOS:000222831900007 AU - Darer, J. D. AU - Hwang, W. AU - Pham, H. H. AU - Bass, E. B. AU - Anderson, G. DA - Jun DO - 10.1097/00001888-200406000-00009 IS - 6 N1 - Darer, JD Hwang, W Pham, HH Bass, EB Anderson, G Bass, Eric/0000-0001-9106-527X 1938-808x PY - 2004 SN - 1040-2446 SP - 541-548 ST - More training needed in chronic care: A survey of US physicians T2 - Academic Medicine TI - More training needed in chronic care: A survey of US physicians UR - ://WOS:000222831900007 VL - 79 ID - 2791 ER - TY - JOUR AB - Background Functional Abdominal Pain Disorders (FAPDs) present a considerable burden to paediatric patients, impacting quality of life, school attendance and causing higher rates of anxiety and depression disorders. There are no international guidelines for the management of this condition. A previous Cochrane Review in 2011 found no evidence to support the use of antidepressants in this context. Objectives To evaluate the current evidence for the efficacy and safety of antidepressants for FAPDs in children and adolescents. Search methods In this updated review, we searched the Cochrane Library, PubMed, MEDLINE, Embase, PsycINFO and two clinical trial registers from inception until 03 February 2020. We also updated our search of databases of ongoing research, reference lists and 'grey literature' from inception to 03 February 2020. Selection criteria We included randomised controlled trials (RCTs) comparing antidepressants to placebo, to no treatment or to any other intervention, in children aged 4 to 18 years with a FAPD diagnosis as per the Rome or any other defined criteria (as defined by the authors). The primary outcomes of interest included treatment success (as defined by the authors), pain severity, pain frequency and withdrawal due to adverse events. Data collection and analysis Two review authors checked all citations independently, resolving disagreement with a third-party arbiter. We reviewed all potential studies in full text, and once again made independent decisions, with disagreements resolved by consensus. We conducted data extraction and 'Risk of bias' assessments independently, following Cochrane methods. Where homogeneous data were available, we performed metaanalysis using a random-effects model. We conducted GRADE analysis. Main results We found one new study in this updated search, making a total of three trials (223 participants) eligible for inclusion: two using amitriptyline (AMI) and one using citalopram.For the primary outcome of treatment success, two studies used reports of success on a symptom-based Likert scale, with either a twopoint reduction or the two lowest levels defined as success. The third study defined success as a 15% improvement in quality of life (QOL) ratings scales. Therefore, meta-analysis did not include this final study due to the heterogeneity of the outcome measure. There is lowcertainty evidence that there may be no difference when antidepressants are compared with placebo (risk ratio (RR) 1.17, 95% confidence interval (CI) 0.87 to 1.56; 2 studies, 205 participants; I-2 = 0%). We downgraded the evidence for significant imprecision due to extremely sparse data (see Summary of findings table 1). The third study reported that participants receiving antidepressants were significantly more likely than those receiving placebo to experience at least a 15% improvement in overall QOL score at 10 and 13 weeks (P = 0.007 and P = 0.002, respectively (absolute figures were not given)). The analysis found no difference in withdrawals due to adverse events between antidepressants and placebo: RR 3.17 (95% CI 0.65 to 15.33), with very low certainty due to high risk of bias in studies and imprecision due to low event and participant numbers. Sensitivity analysis using a fixed-eHect model and analysing just for AMI found no change in this result. Due to heterogeneous and limited reporting, no further meta-analysis was possible. Authors' conclusions There may be no difference between antidepressants and placebo for treatment success of FAPDs in childhood. There may be no difference in withdrawals due to adverse events, but this is also of low certainty. There is currently no evidence to support clinical decision making regarding the use of these medications. Further studies must consider sample size, homogenous and relevant outcome measures and longer follow up. AN - WOS:000624575100034 AU - de Bruijn, C. M. A. AU - Rexwinkel, R. AU - Gordon, M. AU - Benninga, M. AU - Tabbers, M. M. C7 - Cd008013 DO - 10.1002/14651858.CD008013.pub3 IS - 2 N1 - de Bruijn, Clara Marieke Andrea Rexwinkel, Robyn Gordon, Morris Benninga, Ma Tabbers, Merit M. Gordon, Morris/0000-0002-1216-5158 1361-6137 PY - 2021 SN - 1469-493X ST - Antidepressants for functional abdominal pain disorders in children and adolescents (Review) T2 - Cochrane Database of Systematic Reviews TI - Antidepressants for functional abdominal pain disorders in children and adolescents (Review) UR - ://WOS:000624575100034 ID - 1768 ER - TY - JOUR AB - Background and Objectives: Dysmenorrhea is commonly categorized into two types; primary and secondary. Primary dysmenorrhea (PD) is the focus of this review. PD is defined as painful menses with cramping sensation in the lower abdomen that is often accompanied by other symptoms, such as sweating, headache, nausea, vomiting, diarrhea, and tremulousness. All these symptoms occur just before or during the menses in women with normal pelvic anatomy. In adolescents the prevalence of PD varies between 16% and 93%, with severe pain perceived in 2% to 29% of the studied girls. Several studies suggest that severe menstrual pain is associated with absenteeism from school or work and limitation of other daily activities. One-third to one-half of females with PD are missing school or work at least once per cycle, and more frequently in 5% to 14% Of them. The wide variation in the prevalence rates may be attributed to the use of selected groups of subjects. Many risk factors are associated with increased severity of dysmenorrhea including earlier age at menarche, long menstrual periods, heavy menstrual flow, smoking and positive family history. Young women using oral contraceptive pills (OCP) report less severe dysmenorrhea. The considerably high prevalence of dysmenorrhea among adolescents verified that this condition is a significant public health problem that requires great attention. Summary of Main Results: Many methodological problems are encountered during quantifying and grading severity of pain related to dysmenorrhea. Quantifying and assessment tools depend on women's self-reporting with potential bias. There is a scarcity of longitudinal studies on the natural history of dysmenorrhea as well as the possible effects of many modifiable risk factors. In addition, the duration of follow-up in the available studies is relatively short. Therefore, several aspects are still open for research. Medical treatment for dysmenorrhea includes anti-inflammatory drugs (NSAIDs), OCP or surgical intervention. The efficacy of conventional treatments using NSAIDs and OCP is high. However, failure rate may reach up to 20% to 25%, besides the occurrence of drug-associated adverse effects. Only 6% of adolescents receive medical advice to treat dysmenorrhea while 70% practice self-management. Unfortunately, some girls even abuse these medications (non-therapeutic high doses) for quick pain relief. The persistence of dysmenorrhea despite the use of OCP and/or NSAIDs drugs is a strong indicator of an organic pelvic disease. This condition mandates an appropriate referral to a gynecologist with proper laparoscopic diagnosis of endometriosis and/or other pelvic diseases. Conclusions: Dysmenorrhea is an important health problem for adolescent., school and occupational as well as practitioners that adversely affects the daily activities and quality of life for adolescent women. The accurate prevalence of dysmenorrhea is difficult to establish due to the variety of diagnostic criteria and the subjective nature of the symptoms. In adolescents, moderate to severe dysmenorrhea that affects lifestyle and does not respond to medical treatment requires professional attention and proper diagnosis of possible underlying pelvic disease. Therefore, adolescent care providers should be more knowledgeable and actively involved in the care of dysmenorrhea. AN - WOS:000368465300004 AU - De Sanctis, V. AU - Soliman, A. AU - Bernasconi, S. AU - Bianchin, L. AU - Bona, G. AU - Bozzola, M. AU - Buzi, F. AU - De Sanctis, C. AU - Tonini, G. AU - Rigon, F. AU - Perissinotto, E. DA - Dec IS - 2 N1 - De Sanctis, Vincenzo Soliman, Ashraf Bernasconi, Sergio Bianchin, Luigi Bona, Gianni Bozzola, Mauro Buzi, Fabio De Sanctis, Carlo Tonini, Giorgio Rigon, Franco Perissinotto, Egle Bernasconi, Sergio/AAA-9419-2021 Soliman, ashraf/0000-0002-7145-6561 PY - 2015 SN - 1565-4753 SP - 512-520 ST - Primary Dysmenorrhea in Adolescents: Prevalence, Impact and Recent Knowledge T2 - Pediatric Endocrinology Reviews Per TI - Primary Dysmenorrhea in Adolescents: Prevalence, Impact and Recent Knowledge UR - ://WOS:000368465300004 VL - 13 ID - 2202 ER - TY - JOUR AB - The objective was to determine the prevalence of lower back pain in adolescents and its relationship to sports and sedentary activities. We conducted a cross-sectional study of 5th to 8th-grade students (n = 1,236) in Bauru, Sao Paulo State, Brazil. We used a structured protocol and the Nordic questionnaire for musculoskeletal symptoms. The analysis was performed using a descriptive approach and bivariate and multivariate binary logistic regression. Prevalence of lower back pain was 19.5% (7% in boys and 12.5% in girls), with statistically significant differences according to gender (p < 0.00001), age (p = 0.0057), and sports (p = 0.0001). Bivariate and multivariate analyses showed independent associations between lower back pain and female gender, time watching TV, and sports. Lower back pain in schoolchildren can persist as chronic pain in adults. Understanding the relationships between variables should provide useful measures for maintaining, improving, and promoting students' wellbeing. AN - WOS:000294439000007 AU - De Vitta, A. AU - Martinez, M. G. AU - Piza, N. T. AU - Simeao, Sfdp AU - Ferreira, N. P. DA - Aug DO - 10.1590/s0102-311x2011000800007 IS - 8 N1 - De Vitta, Alberto Martinez, Mariana Goncalez Piza, Nathalia Toledo de Almeida Penteado Simeao, Sandra Fiorelli Ferreira, Nathalia Pascucci De Vitta, Alberto/AAV-2210-2020 1678-4464 PY - 2011 SN - 0102-311X SP - 1520-1528 ST - Prevalence of lower back pain and associated factors in students T2 - Cadernos De Saude Publica TI - Prevalence of lower back pain and associated factors in students UR - ://WOS:000294439000007 VL - 27 ID - 2482 ER - TY - JOUR AB - OBJECTIVE: To evaluate the currently published data pertaining to the efficacy and safety of topiramate for prophylaxis of classic and common migraine in pediatric patients. DATA SOURCES: The literature was identified via PubMed (through April 2013) and Iowa Drug Information System (through April 2013). References from identified articles were also reviewed. STUDY SELECTION AND DATA EXTRACTION: Data were included from studies of efficacy and safety in pediatric patients experiencing migraine (with or without aura), as defined by the International Headache Society. Studies including patients with more specific types of migraine, such as basilar migraine, were excluded. DATA SYNTHESIS: Eight publicatons were identified, including 3 randomized controlled trials (RCTs), a subgroup analysis, and 4 observational studies. These studies reported a decrease in headache frequency ranging from 63% to 100% for doses of 100 mg/d and 65% for 200 mg/d. Response to therapy, defined as ≥50% reduction in migraine rate, was also reported in 83% to 95% of patients receiving topiramate. Topiramate is generally well tolerated. Adverse effects were dose related and included paresthesias, weight loss, and cognitive adverse effects. CONCLUSION: Topiramate is an effective and well-tolerated prophylactic therapy for use in pediatric migraine patients. Doses of 100 and 200 mg/d (1.47-2.0 mg/kg/d) effectively decrease the frequency of migraine headaches, with 100 mg/d providing optimal benefit-to-risk ratio. Additional randomized, double-blind, placebo-controlled studies are needed to determine the impact of the drug on quality-of-life outcomes, such as school function, and migraine severity and duration. AD - University of Toledo, Toledo, OH, USA. AN - 24566461 AU - Deaton, T. L. AU - Mauro, L. S. DA - May DO - 10.1177/1060028014521128 DP - NLM ET - 2014/02/26 IS - 5 KW - Child Fructose/adverse effects/*analogs & derivatives/therapeutic use Humans Migraine Disorders/*prevention & control Neuroprotective Agents/adverse effects/*therapeutic use Topiramate Treatment Outcome adolescent migraine pediatric prophylaxis LA - eng N1 - 1542-6270 Deaton, Tamara L Mauro, Laurie S Journal Article Review United States Ann Pharmacother. 2014 May;48(5):638-43. doi: 10.1177/1060028014521128. Epub 2014 Feb 24. PY - 2014 SN - 1060-0280 SP - 638-43 ST - Topiramate for migraine prophylaxis in pediatric patients T2 - Ann Pharmacother TI - Topiramate for migraine prophylaxis in pediatric patients VL - 48 ID - 3754 ER - TY - JOUR AB - The first attack of hemiplegic migraine occurred in most cases between the 10th and 15th year of life in 14 children (8 boys and 6 girls). Most attacks took place with intervals of 3-6 and 6-12 months. Only rarely did they last longer than 24 hours. Precipitating factors (emotional and physical stress, change of weather, influence of light or heat) were given in 6 cases. As many as 7 children attended higher schools with good or average success. A family history, mainly from the maternal side, existed in 11 cases. Sensory symptoms were demonstrable in all children, motor symptoms in 9 and visual symptoms in 13. Ten children had speech disturbances. Hand, lower arm, cheek and tongue were most frequently involved in sensory and motor symptoms. Out of 9 attacks registered with an EEG severe focal signs (delta or theta-delta foci) were demonstrable contralaterally in all children, in 8 children there were also signs of generalized disturbances. AN - 7371528 AU - Degen, R. AU - Degen, H. E. AU - Palm, D. AU - Meiser, W. DA - May 2 DO - 10.1055/s-2008-1070721 DP - NLM ET - 1980/05/02 IS - 18 KW - Adolescent Adult Age Factors Child Electroencephalography Female Hemiplegia/*complications Humans Male Migraine Disorders/complications/*diagnosis/genetics Nervous System Diseases/complications Sensation Speech Disorders/complications Vision Disorders/complications LA - ger N1 - Degen, R Degen, H E Palm, D Meiser, W English Abstract Journal Article Germany Dtsch Med Wochenschr. 1980 May 2;105(18):640-5. doi: 10.1055/s-2008-1070721. OP - Die Migraine hémiphlégique im Kindesalter. PY - 1980 SN - 0012-0472 (Print) 0012-0472 SP - 640-5 ST - [Hemiplegic migraine in childhood (author's transl)] T2 - Dtsch Med Wochenschr TI - [Hemiplegic migraine in childhood (author's transl)] VL - 105 ID - 3462 ER - TY - JOUR AB - BACKGROUND: Ethiopian school children often carry school supplies in heavy school bags and encounter limited school facilities. This stresses their vulnerable musculoskeletal system and may result in experiencing musculoskeletal pain. High prevalence of musculoskeletal pain has been documented, but data on musculoskeletal pain among elementary school children in Ethiopia is lacking. To determine the prevalence of musculoskeletal pain and associated factors among elementary school children in Gondar, Ethiopia. METHODS: Cross-sectional study was conducted among children from six randomly selected elementary schools. Sample size was determined proportionally across school grades and governmental and private schools to ensure variety within the sample. Data collection consisted of physical measurements including height, weight and schoolbag weight, and a structured questionnaire on musculoskeletal pain, mode of transport, walking time and school facilities. Data were analysed descriptively and through uni- and multivariate logistic regression model. RESULTS: In total 723 children participated. The overall prevalence of self-reported musculoskeletal pain was 62%, with a significant difference between school types (governmental 68% versus private 51%). Shoulder, neck and lower leg/knee were most commonly reported. Walking to and from school for ≥20 min (OR = 2.94, 95% CI 2.05 to 4.21) and relative school bag weight (OR = 2.57, 95% CI 1.48 to 4.47) were found significantly associated with self-report musculoskeletal pain. Children with carrying heavy school supplies and also walking long duration have a 3.5 (95% CI = 1.80-6.95) times greater chance of reporting pain as compared to those who carry lesser weighed bags and reported shorter walking duration at the same time. CONCLUSIONS: Prevalence of self-reported musculoskeletal pain was high among children attending public schools and also those who walked a long way to and from school. Long walking duration and relative school bag weight were significantly associated with musculoskeletal pain. These findings can inform policymakers to provide transportation services and other facilities at elementary schools. The findings of this study should be interpreted with caution due to possible social desirability bias with higher prevalence of self-reported pain and more so in children population. AU - Delele, Manayesh AU - Janakiraman, Balamurugan AU - Bekele Abebe, Abey AU - Tafese, Ararso AU - van de Water, Alexander T. M. DA - 2018/07/31/ DO - 10.1186/s12891-018-2192-6 DP - PubMed IS - 1 J2 - BMC Musculoskelet Disord KW - Adolescent Adolescent Development Age Distribution Child Child Development Child, Preschool Cross-Sectional Studies Ethiopia Female Humans Lifting Male Musculoskeletal pain Musculoskeletal System Prevalence Private Sector Public Sector Risk Factors School bag School children Schools Students Time Factors Walking Walking distance Weight-Bearing LA - eng PY - 2018 SN - 1471-2474 SP - 276 ST - Musculoskeletal pain and associated factors among Ethiopian elementary school children T2 - BMC musculoskeletal disorders TI - Musculoskeletal pain and associated factors among Ethiopian elementary school children UR - http://www.ncbi.nlm.nih.gov/pubmed/30064400 VL - 19 ID - 65 ER - TY - JOUR AB - Little is known about adherence to antiretroviral therapy (ART) among adolescents in sub-Saharan Africa, where the majority of the world's HIV-positive adolescents reside. We assessed individual, household, and HIV self-management characteristics associated with a 48-hour treatment gap in the preceding 3 months, and a pharmacy medication possession ratio (MPR) that assessed the number of ART pills dispensed divided by the number of ART pills required in the past 6 months, among 285 Zambians, ages 15-19 years. Factors significantly associated with a 48-hour treatment gap were being male, not everyone at home being aware of the adolescent's HIV status, and alcohol use in the past month. Factors associated with an MPR < 90% included attending the clinic alone, alcohol use in the past month, and currently not being in school. Findings support programs to strengthen adolescents' HIV management skills with attention to alcohol use, family engagement, and the challenges adolescents face transitioning into adulthood, especially when they are no longer in school. AD - Department of International Health, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street E5032, Baltimore, MD, 21205, USA. jdenison@jhu.edu. Reproductive, Maternal, Newborn, Child Health Division, FHI 360, Durham, NC, USA. Contraceptive Technology Innovation Department, FHI 360, Durham, NC, USA. FHI 360, Ndola, Zambia. Health Services Research, FHI 360, Durham, NC, USA. FHI 360, Lusaka, Zambia. Arthur Davison Children's Hospital, Ndola, Zambia. AN - 29103190 AU - Denison, J. A. AU - Packer, C. AU - Stalter, R. M. AU - Banda, H. AU - Mercer, S. AU - Nyambe, N. AU - Katayamoyo, P. AU - Mwansa, J. K. AU - McCarraher, D. R. DA - Mar DO - 10.1007/s10461-017-1944-x DP - NLM ET - 2017/11/06 IS - 3 KW - Adolescent Alcohol Drinking/*adverse effects/epidemiology Ambulatory Care Facilities Antiretroviral Therapy, Highly Active/*methods Cross-Sectional Studies Family Characteristics Female HIV Infections/*drug therapy/epidemiology/*psychology Humans Male Medication Adherence/psychology/*statistics & numerical data Pain Management Schools Young Adult Zambia/epidemiology *Adherence *Adolescents *Antiretroviral therapy (ART) *Caregivers *hiv *Sub-Saharan Africa *Youth *Zambia LA - eng N1 - 1573-3254 Denison, Julie A Packer, Catherine Stalter, Randy M Banda, Harry Mercer, Sarah Nyambe, Namakau Katayamoyo, Patrick Mwansa, Jonathan K McCarraher, Donna R P30 AI094189/AI/NIAID NIH HHS/United States Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. United States AIDS Behav. 2018 Mar;22(3):996-1005. doi: 10.1007/s10461-017-1944-x. PY - 2018 SN - 1090-7165 SP - 996-1005 ST - Factors Related to Incomplete Adherence to Antiretroviral Therapy among Adolescents Attending Three HIV Clinics in the Copperbelt, Zambia T2 - AIDS Behav TI - Factors Related to Incomplete Adherence to Antiretroviral Therapy among Adolescents Attending Three HIV Clinics in the Copperbelt, Zambia VL - 22 ID - 3889 ER - TY - JOUR AB - Background: Foreign body (FB) ingestions are common in children presenting to the emergency department. Health care providers are quickly challenged to determine which children need urgent endoscopy for diagnostic or therapeutic reasons. We performed a retrospective study to determine if esophageal injury caused by FB ingestion correlated to presenting signs or symptoms, location of impaction, duration of impaction, or denomination of coin (as this was the most commonly ingested FB). Methods: A retrospective chart review of children between birth and 17 years of age who presented for esophagogastroduodenoscopy for removal of upper gastrointestinal FB was performed. Demographic data collected from all children included age, sex, and race. For children with FB ingestion, the type of FB, location of the FB, underlying gastrointestinal pathology, duration of impaction, and endoscopic findings were recorded. Descriptive analysis of the data was performed using means, medians, SD, and percentages; chi(2) test was used to test the association between categorical variables. Results: Over a 10-year period of review, a total of 3279 esophago-gastroduodenoscopies were performed; 248 (7.8%) were done for FB removal. The mean age for children having endoscopy for FB removal was 3.9 (SD, 3.2) years (median, 3.1 years); there was a slight male predominance (male/female ratio = 1.6:1). The vast majority (81%) of retained FBs was coins. Most of the FBs were located in the upper esophagus (68%). Success rate for retrieval was greater for esophageal FBs (99%) than for more distally located FBs (70%; P < 0.001). Mucosal ulceration, seen in 59 children (30%), was related to a complaint of substernal pain but not vomiting, respiratory distress, or drooling. The finding of esophageal ulceration was not related to location of coin impaction or denomination of ingested coin but was related to duration of impaction and the unexpected finding of FB during chest radiograph. Underlying pathology was found more commonly in children with meat bolus impaction (100%) than in children with other FB ingestions (3.6%; P < 0.001). Conclusions: Ingestion of FBs by children remains a significant problem faced by emergency department personnel. In our study, a complaint of substernal chest pain in children with an esophageal FB predicted esophageal ulceration. Also, esophageal FBs unexpectedly found on chest radiograph or known to be present greater than 72 hours were more likely to have esophageal ulceration. These clinical and historic clues can help direct appropriate prompt referral for endoscopic removal. AN - WOS:000307803500001 AU - Denney, W. AU - Ahmad, N. AU - Dillard, B. AU - Nowicki, M. J. DA - Aug DO - 10.1097/PEC.0b013e31826248eb IS - 8 N1 - Denney, William Ahmad, Naveed Dillard, Benjamin Nowicki, Michael J. 1535-1815 PY - 2012 SN - 0749-5161 SP - 731-734 ST - Children Will Eat the Strangest Things A 10-Year Retrospective Analysis of Foreign Body and Caustic Ingestions From a Single Academic Center T2 - Pediatric Emergency Care TI - Children Will Eat the Strangest Things A 10-Year Retrospective Analysis of Foreign Body and Caustic Ingestions From a Single Academic Center UR - ://WOS:000307803500001 VL - 28 ID - 2420 ER - TY - JOUR AB - CONTEXT AND OBJECTIVE: Chronic spinal pain, especially low-back pain and neck pain, is a leading cause of years of life with disability. The aim of the present study was to estimate the prevalence of chronic spinal pain among individuals aged 15 years or older and to identify the factors associated with it. DESIGN AND SETTING: Cross-sectional epidemiological study on a sample of the population of the city of São Paulo. METHOD: Participants were selected using random probabilistic sampling and data were collected via face-to-face interviews. The Hospital Anxiety and Depression Scale (HADS), EuroQol-5D, Alcohol Use Disorders Identification Test (AUDIT), Fagerström test for nicotine dependence and Brazilian economic classification criteria were used. RESULTS: A total of 826 participants were interviewed. The estimated prevalence of chronic spinal pain was 22% (95% confidence interval, CI: 19.3-25.0%). The factors independently associated with chronic spinal pain were: female sex, age 30 years or older, schooling level of four years or less, symptoms compatible with anxiety and high physical exertion during the main occupation. Quality of life and self-rated health scores were significantly worse among individuals with chronic spinal pain. CONCLUSION: The prevalence of chronic spinal pain in this segment of the population of São Paulo was 22.0%. The factors independently associated with chronic pain were: female sex, age 30 years or older, low education, symptoms compatible with anxiety and physical exertion during the main occupation. AD - DC, MSc. Associate Professor, Instituto Paulista de Pós-Graduação (IPPG), São Paulo, SP, Brazil. MD, DC, PhD. Private Practice, Axis Clinica de Coluna, São Paulo, SP, Brazil. DC, MSc. Associate Professor, Universidade Anhembi Morumbi, São Paulo, SP, Brazil. MD, PhD. Professor, Department of Preventive Medicine, Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil. AN - 27901240 AU - Depintor, J. D. AU - Bracher, E. S. AU - Cabral, D. M. AU - Eluf-Neto, J. DA - Sep-Oct DO - 10.1590/1516-3180.2016.0091310516 DP - NLM ET - 2016/12/03 IS - 5 KW - Adolescent Adult Age Distribution Age Factors Aged Back Pain/*epidemiology/*etiology Brazil/epidemiology Chronic Pain/*epidemiology/*etiology Cross-Sectional Studies Female Humans Male Middle Aged Multivariate Analysis Neck Pain/*epidemiology/*etiology Prevalence Quality of Life Risk Factors Sex Distribution Sex Factors Socioeconomic Factors Surveys and Questionnaires Young Adult LA - eng N1 - 1806-9460 Depintor, Jidiene Dylese Presecatan Bracher, Eduardo Sawaya Botelho Cabral, Dayane Maia Costa Eluf-Neto, José Journal Article Brazil Sao Paulo Med J. 2016 Sep-Oct;134(5):375-384. doi: 10.1590/1516-3180.2016.0091310516. PY - 2016 SN - 1516-3180 SP - 375-384 ST - Prevalence of chronic spinal pain and identification of associated factors in a sample of the population of São Paulo, Brazil: cross-sectional study T2 - Sao Paulo Med J TI - Prevalence of chronic spinal pain and identification of associated factors in a sample of the population of São Paulo, Brazil: cross-sectional study VL - 134 ID - 3539 ER - TY - JOUR AB - BACKGROUND: Studies done in Saudi Arabia showed a high prevalence of headache among university students. Limited research was done to assess the relationship between headache and psychiatric disorders. The aim of this study was to assess the prevalence and association between migraine, tension-type headache, and depression among Saudi female students in Taif University. PARTICIPANTS AND METHODS: A cross-sectional study using self-administered questionnaires about headache and depression was conducted at the Taif University on 1340 female students in the academic year 2016-2017. The Beck Depression Inventory, the ID Migraine™ screening tool, and the criteria of the International Headache Society were used to investigate the depressive symptoms and headache types. RESULTS: The self-reported headache prevalence was 68.4%, and the prevalence of migraine, tension-type headache (TTH), and depression was 32.5%, 29.5%, and 6.2%, respectively. The main migraine trigger was stress or anxiety; 86.6% of migraineurs had a positive family history, and only 11.9% sought medical care for headache. Of students with TTH, 61.1% reported family history and only 12.4% sought medical care. Paracetamol was the commonly used analgesic for all headache types. Medical students and students in older grades showed significantly higher levels of all headache types. Depression prevalence was significantly higher among migraineurs and students who suffered higher headache frequencies. CONCLUSION: The study demonstrated a high prevalence of headache among the studied students and an association between headache and depression. The study calls for increasing awareness towards headache and the importance of seeking medical consultation. Management strategies should be planned for the observed headache and depression comorbidity. AD - 1Department of Family and Community Medicine, College of Medicine, Taif University, Alsalama street, Taif city, Saudi Arabia. ISNI: 0000 0004 0419 5255. GRID: grid.412895.3 2Department of Public Health and Community Medicine, Faculty of Medicine, Menoufia University, Shibin El Kom, Egypt. ISNI: 0000 0004 0621 4712. GRID: grid.411775.1 AN - 30774147 AU - Desouky, D. E. AU - Zaid, H. A. AU - Taha, A. A. C2 - PMC6351506 DO - 10.1186/s42506-019-0008-7 DP - NLM ET - 2019/02/19 IS - 1 KW - Acetaminophen/therapeutic use Adult Analgesics, Non-Narcotic/therapeutic use Anxiety/epidemiology Comorbidity Cross-Sectional Studies Depression/*epidemiology Female Humans Migraine Disorders/drug therapy/*epidemiology Prevalence Psychiatric Status Rating Scales Saudi Arabia/epidemiology Stress, Psychological/epidemiology Students/*statistics & numerical data Tension-Type Headache/drug therapy/*epidemiology Universities Young Adult Depression Headache Migraine Saudi University University and from the deanships of the colleges included in the study. As long as the study does not take samples from humans, there is no probability of a potential harm and all students were more than 18 years, the ethics committee approved obtaining verbal consents from the respondent students before sharing in the studyThe manuscript does not contain any individual person’s data in any form (individual details, images or videos).The authors declare that they have no competing interests.Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. LA - eng N1 - 2090-262x Desouky, Dalia E Zaid, Hany A Taha, Azza A Journal Article J Egypt Public Health Assoc. 2019;94(1):7. doi: 10.1186/s42506-019-0008-7. Epub 2019 Jan 29. PY - 2019 SN - 0013-2446 (Print) 0013-2446 SP - 7 ST - Migraine, tension-type headache, and depression among Saudi female students in Taif University T2 - J Egypt Public Health Assoc TI - Migraine, tension-type headache, and depression among Saudi female students in Taif University VL - 94 ID - 3534 ER - TY - JOUR AB - Little is known about the prevalence of functional gastrointestinal diseases (FGDs) in adolescents, especially in developing countries. This cross-sectional survey conducted in a semi-urban school in Sri Lanka, assessed the prevalence of whole spectrum of FGDs in 427 adolescents (age 12-16 years) using a validated self-administered questionnaire. According to Rome III criteria, 123 (28.8%) adolescents had FGDs. Of them, 59 (13.8%) had abdominal-pain-related FGDs [irritable bowel syndrome (IBS) 30, functional dyspepsia 15, functional abdominal pain 13 and abdominal migraine 1]. Prevalence of functional constipation, aerophagia, adolescent rumination syndrome, cyclical vomiting syndrome and non-retentive faecal incontinence were 4.2, 6.3, 4, 0.5 and 0.2%, respectively. Only 58 (13.6%) adolescents were found to have FGDs when Rome II criteria were used. In conclusion, FGDs were present in more than one-fourth of adolescents in the study group, of which IBS was the most common. Rome III criteria were able to diagnose FGDs more comprehensively than Rome II. AD - Department of Physiology, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka. niranga1230@lycos.com AN - 20525779 AU - Devanarayana, N. M. AU - Adhikari, C. AU - Pannala, W. AU - Rajindrajith, S. DA - Feb DO - 10.1093/tropej/fmq039 DP - NLM ET - 2010/06/08 IS - 1 KW - Abdominal Pain/diagnosis/epidemiology/etiology Adolescent Aerophagy/diagnosis/*epidemiology Child Constipation/diagnosis/*epidemiology Cross-Sectional Studies Dyspepsia/diagnosis/*epidemiology Fecal Incontinence/epidemiology Female Gastrointestinal Diseases/*classification/diagnosis/*epidemiology Humans Male Migraine Disorders/classification/diagnosis Prevalence Severity of Illness Index Sri Lanka/epidemiology Surveys and Questionnaires Vomiting LA - eng N1 - 1465-3664 Devanarayana, Niranga Manjuri Adhikari, Chandralatha Pannala, Waruni Rajindrajith, Shaman Comparative Study Journal Article England J Trop Pediatr. 2011 Feb;57(1):34-9. doi: 10.1093/tropej/fmq039. Epub 2010 Jun 4. PY - 2011 SN - 0142-6338 SP - 34-9 ST - Prevalence of functional gastrointestinal diseases in a cohort of Sri Lankan adolescents: comparison between Rome II and Rome III criteria T2 - J Trop Pediatr TI - Prevalence of functional gastrointestinal diseases in a cohort of Sri Lankan adolescents: comparison between Rome II and Rome III criteria VL - 57 ID - 3615 ER - TY - JOUR AB - Background and Objective: Functional gastrointestinal disorders (FGD) are common among children, but little is known regarding their prevalence in developing countries. We assessed the prevalence of abdominal pain-predominant FGD, in addition to the predisposing factors and symptomatology, in Sri Lankan children. Patients and Methods: A cross-sectional survey was conducted among a randomly selected group of 10-to 16-year-olds in 8 randomly selected schools in 4 provinces in Sri Lanka. A validated, self-administered questionnaire was completed by children independently in an examination setting. FGD were diagnosed using Rome III criteria. Results: A total of 2180 questionnaires were distributed and 2163 (99.2%) were included in the analysis (1189 [55%] boys, mean age 13.4 years, standard deviation 1.8 years). Of them, 270 (12.5%) had at least 1 abdominal pain-predominant FGD. Irritable bowel syndrome (IBS) was seen in 107 (4.9%), functional dyspepsia in 54 (2.5%), functional abdominal pain in 96 (4.4%), and abdominal migraine (AM) in 21 (1.0%) (2 had AM and functional dyspepsia, 6 had AM and IBS). Extraintestinal symptoms were more common among affected children (P < 0.05). Abdominal pain-predominant FGD were higher in girls and those exposed to stressful events (P < 0.05). Prevalence negatively correlated with age (r = -0.05, P = 0.02). Conclusions: Abdominal pain-predominant FGD affects 12.5% of children ages 10 to 16 years and constitutes a significant health problem in Sri Lanka. IBS is the most common FGD subtype present. Abdominal pain-predominant FGD are higher in girls and those exposed to emotional stress. Prevalence of FGD decreased with age. Extraintestinal symptoms are more frequent in affected children. AN - WOS:000297542700016 AU - Devanarayana, N. M. AU - Mettananda, S. AU - Liyanarachchi, C. AU - Nanayakkara, N. AU - Mendis, N. AU - Perera, N. AU - Rajindrajith, S. DA - Dec DO - 10.1097/MPG.0b013e3182296033 IS - 6 N1 - Devanarayana, Niranga Manjuri Mettananda, Sachith Liyanarachchi, Chathurangi Nanayakkara, Navoda Mendis, Niranjala Perera, Nimnadi Rajindrajith, Shaman Mettananda, Sachith/H-4640-2019 Mettananda, Sachith/0000-0002-0760-0418; Devanarayana, Niranga Manjuri/0000-0002-2988-110X 1536-4801 PY - 2011 SN - 0277-2116 SP - 659-665 ST - Abdominal Pain-Predominant Functional Gastrointestinal Diseases in Children and Adolescents: Prevalence, Symptomatology, and Association With Emotional Stress T2 - Journal of Pediatric Gastroenterology and Nutrition TI - Abdominal Pain-Predominant Functional Gastrointestinal Diseases in Children and Adolescents: Prevalence, Symptomatology, and Association With Emotional Stress UR - ://WOS:000297542700016 VL - 53 ID - 2466 ER - TY - JOUR AB - Background: Abdominal pain predominant functional gastrointestinal diseases (AP-FGD) are commonly seen in the paediatric age group. It has significant impact on daily activities of affected children. Main objective of this study was to assess the health related quality of life (HRQoL) in children with AP-FGD. Method: This was a cross sectional survey conducted in children aged 13-18 years, in four randomly selected schools in Western province of Sri Lanka. Data was collected using a previously validated, self-administered questionnaire. It had questions on symptoms, HRQoL and health care consultation. AP-FGD were diagnosed using Rome III criteria. Results: A total of 1850 questionnaires were included in the analysis [males 1000 (54.1%), mean age 14.4 years and SD 1.3 years]. Of them, 305 (16.5%) had AP-FGD [irritable bowel syndrome = 91(4.9%), functional dyspepsia = 11 (0.6%), abdominal migraine = 37 (1.9%) and functional abdominal pain = 180 (9.7%)]. Lower HRQoL scores for physical (83.6 vs. 91.4 in controls), social (85.0 vs. 92.7), emotional (73.6 vs. 82.7) and school (75.0 vs. 82.5) functioning domains, and lower overall scores (79.6 vs. 88.0) were seen in children with AP-FGD (p < 0.001). A weak but significant negative correlation was observed between HRQoL score and severity of abdominal pain (r = -0.24, p < 0.0001). Eighty five children (27.9%) had sought healthcare for AP-FGD. Factors determining healthcare seeking were presence of abdominal bloating and vomiting (p < 0.05). Conclusions: Children with AP-FGD have lower quality of life in all 4 domains. Those with severe symptoms have lower HRQoL. Approximately 28% of children with AP-FGD seek healthcare for their symptoms. AN - WOS:000340921600001 AU - Devanarayana, N. M. AU - Rajindrajith, S. AU - Benninga, M. A. C7 - 150 DA - Aug DO - 10.1186/1471-230x-14-150 N1 - Devanarayana, Niranga Manjuri Rajindrajith, Shaman Benninga, Marc A. Devanarayana, Niranga Manjuri/0000-0002-2988-110X 1471-230x PY - 2014 ST - Quality of life and health care consultation in 13 to 18 year olds with abdominal pain predominant functional gastrointestinal diseases T2 - Bmc Gastroenterology TI - Quality of life and health care consultation in 13 to 18 year olds with abdominal pain predominant functional gastrointestinal diseases UR - ://WOS:000340921600001 VL - 14 ID - 2293 ER - TY - JOUR AB - Context: Recurrent abdominal pain is one of the commonest gastrointestinal complaints in children, affecting approximately 10% of school aged children and adolescents. There is no consensus with regards to etiology, investigation and management of this common problem. This review addresses some of the issues related to epidemiology, etiology, management and prognosis of recurrent abdominal pain. Evidence acquisition: We reviewed current literature on this broad subject, specially concentrating on epidemiology, etiology and, basic and advanced management strategies, from 1958 to date, using PubMed, Embase, Cochrane database and cross references. Results: The majority of the affected children have functional gastrointestinal diseases. The exact cause of pain remains obscure. New evidence suggests that emotional stress, visceral hypersensitivity and gastrointestinal motility disorders may play a vital part in its origin. Pharmacological treatments are commonly used in an effort to manage symptoms, despite the lack of data supporting their efficacy. Conclusions: Most children with recurrent abdominal pain have functional gastrointestinal diseases and a detailed history, examination and basic stool, urine and hematological investigations are sufficient to exclude organic pathology in them. Despite the magnitude of the problem, knowledge on the effective management options is poor. AN - WOS:000266355900004 AU - Devanarayana, N. M. AU - Rajindrajith, S. AU - de Silva, H. J. DA - May IS - 5 N1 - Devanarayana, Niranga Manjuri Rajindrajith, Shaman de Silva, H. Janaka Devanarayana, Niranga Manjuri/0000-0002-2988-110X 0974-7559 PY - 2009 SN - 0019-6061 SP - 389-399 ST - Recurrent Abdominal Pain in Children T2 - Indian Pediatrics TI - Recurrent Abdominal Pain in Children UR - ://WOS:000266355900004 VL - 46 ID - 2604 ER - TY - JOUR AB - Abdominal pain-predominant functional gastrointestinal diseases (AP-FGD) are common in children and commonly attributed to exposure to child abuse. However, this relationship has not been studied in teenagers, and the main objective of the current study was to assess it. Teenagers were recruited from four randomly selected schools in Western province of Sri Lanka. Data were collected using a validated self-administered questionnaire. AP-FGD were diagnosed using Rome III criteria. A total of 1850 teenagers aged 13-18 years were included. Three hundred and five (16.5%) had AP-FGD. AP-FGD were significantly higher in those exposed to sexual (34.0%), emotional (25.0%) and physical (20.2%) abuse, than in those not abused (13.0%, p < 0.001). Those with AP-FGD exposed to abuse had a higher severity score for bowel symptoms (30.8% vs. 24.7% in not abused, p < 0.05). This study highlights the importance of identifying exposure to abuse in management of teenagers with AP-FGD. AN - WOS:000343058700010 AU - Devanarayana, N. M. AU - Rajindrajith, S. AU - Perera, M. S. AU - Nishanthanie, S. W. AU - Karunanayake, A. AU - Benninga, M. A. DA - Oct DO - 10.1093/tropej/fmu035 IS - 5 N1 - Devanarayana, Niranga Manjuri Rajindrajith, Shaman Perera, Madushanka S. Nishanthanie, Samudu W. Karunanayake, Amaranath Benninga, Marc A. Karunanayake, Amaranath/AAG-3419-2020 KARUNANAYAKE, AMARANATH/0000-0001-5836-6329; Devanarayana, Niranga Manjuri/0000-0002-2988-110X 1465-3664 PY - 2014 SN - 0142-6338 SP - 386-392 ST - Association Between Functional Gastrointestinal Diseases and Exposure to Abuse in Teenagers T2 - Journal of Tropical Pediatrics TI - Association Between Functional Gastrointestinal Diseases and Exposure to Abuse in Teenagers UR - ://WOS:000343058700010 VL - 60 ID - 2282 ER - TY - JOUR AB - Examined the role of socioecological factors (family functioning and socioeconomic variables) in predicting behavioral and cognitive adaptation in children with sickle cell syndromes (SCD). Participants included 74 African American children and adolescents with SCD and their primary caretakers. Outcomes included internalizing and externalizing behavior symptoms, as rated by caretakers, as well as intellectual abilities and academic achievement, as assessed by individually administered standardized instruments. Family functioning consisted of both caretaker adjustment and family environment (i.e., family adaptability and cohesion). Hierarchical multiple regression analyses revealed that caretaker psychological adjustment predicted externalizing behaviors, while family environment (i.e., adaptability and cohesion) predicted neither behavioral nor cognitive functioning. Socioeconomic variables alone predicted intellectual abilities and academic achievement and also contributed to the prediction of child behavioral adaptation. Results are discussed in terms of relevant sociocultural issues and implications for family-level prevention and intervention. AN - WOS:000076301400006 AU - Devine, D. AU - Brown, R. T. AU - Lambert, R. AU - Donegan, J. E. AU - Eckman, J. DA - Sep DO - 10.1023/a:1026254119939 IS - 3 N1 - Devine, D Brown, RT Lambert, R Donegan, JE Eckman, J Brown, Ronald/0000-0002-9656-4614 PY - 1998 SN - 1068-9583 SP - 295-313 ST - Predictors of psychosocial and cognitive adaptation in children with sickle cell syndromes T2 - Journal of Clinical Psychology in Medical Settings TI - Predictors of psychosocial and cognitive adaptation in children with sickle cell syndromes UR - ://WOS:000076301400006 VL - 5 ID - 2890 ER - TY - JOUR AB - Introduction and aims: Functional gastrointestinal disorders are among the most common chronic disorders in children worldwide. Studies in schoolchildren from various Latin American countries have shown a high prevalence of functional gastrointestinal disorders, but their prevalence in Mexican schoolchildren is unknown. Our aim was to assess the prevalence of functional gastrointestinal disorders in Mexican schoolchildren in accordance with the Rome III criteria. Material and methods: Children and adolescents from public and private schools in Monterrey and Cuernavaca privately completed the Spanish version of the Questionnaire on Pediatric Gastrointestinal Symptoms-Rome III Version (QPGS-III) in class, using the same methods and questionnaires of previous studies conducted by our group in other Latin American countries. Results: A total of 362 schoolchildren (public school 82, private school 280), with a mean age of 11.6 +/- 2.1 years completed the QPGS-III. Ninety-nine schoolchildren (27.3%) met the criteria for a FGID, according to the Rome III criteria. Functional constipation was the most common FGID (12.6%). Irritable bowel syndrome (6.4%) was the most common FGID associated with abdominal pain. There was no significant difference in the prevalence of FGIDs between sexes (P=.8). Conclusions: We found a high prevalence of FGIDs in Mexican school-aged children and adolescents. (C) 2016 Asociacion Mexicana de Gastroenterologia. Published by Masson Doyma Mexico S.A. AN - WOS:000425651900003 AU - Dhroove, G. AU - Saps, M. AU - Garcia-Bueno, C. AU - Jimenez, A. L. AU - Rodriguez-Reynosa, L. L. AU - Velasco-Benitez, C. A. DA - Jan-Mar DO - 10.1016/j.rgmx.2016.05.003 IS - 1 N1 - Dhroove, G. Saps, M. Garcia-Bueno, C. Leyva Jimenez, A. Rodriguez-Reynosa, L. L. Velasco-Benitez, C. A. Velasco-Benitez, Carlos A/0000-0001-5647-3024 PY - 2017 SN - 0375-0906 SP - 13-18 ST - Prevalence of functional gastrointestinal disorders in Mexican schoolchildren T2 - Revista De Gastroenterologia De Mexico TI - Prevalence of functional gastrointestinal disorders in Mexican schoolchildren UR - ://WOS:000425651900003 VL - 82 ID - 2117 ER - TY - JOUR AB - Tension-type headaches, the most prevalent form of headache, are differentiated as being either episodic or chronic. The episodic form is a physiologic response to stress, anxiety, depression, emotional conflicts, fatigue, or repressed hostility. Treatment focuses on the use of over-the-counter or prescribed simple analgesics for pain relief. Successful treatment of the chronic form depends on recognition of depression or persistent anxiety states. Primary care physicians can effectively manage most of these patients with nonhabituating anxiolytic or antidepressant medications; however, referrals for psychotherapy may be required in some cases. When tension-type headaches occur in children and adolescents, the physician must explore the patient's family and social relationships as well as school performance. In addition to nonhabituating drug therapies, family counseling and biofeedback may be helpful. In coexisting migraine and tension-type headaches, nonhabituating analgesics may be used for the relief of acute pain; the use of ergotamine and triptans should be restricted to relief of the hard or sick headache. Tricyclic antidepressants or monoamine oxidase inhibitors are the gold standards for prophylaxis, although the selective serotonin reuptake inhibitors may be indicated in less severe cases. Several forms of biofeedback have also proved effective. Nonetheless, some patients with this form of headache may require psychiatric treatment for severe depression. AD - Diamond Headache Clinic, Chicago, Illinois, USA. AN - 10682186 AU - Diamond, S. DO - 10.1016/s1098-3597(99)90038-8 DP - NLM ET - 2000/02/22 IS - 6 KW - Adult Analgesics/*therapeutic use Anti-Anxiety Agents/therapeutic use Antidepressive Agents, Tricyclic/therapeutic use Anxiety/complications/drug therapy Biofeedback, Psychology Child Depression/complications/drug therapy Humans Prevalence Serotonin/metabolism Stress, Physiological/complications Tension-Type Headache/etiology/prevention & control/*therapy LA - eng N1 - Diamond, S Journal Article Review United States Clin Cornerstone. 1999;1(6):33-44. doi: 10.1016/s1098-3597(99)90038-8. PY - 1999 SN - 1098-3597 (Print) 1873-4480 SP - 33-44 ST - Tension-type headache T2 - Clin Cornerstone TI - Tension-type headache VL - 1 ID - 3532 ER - TY - JOUR AB - Background: Most available data on the prevalence and characteristics of back pain in schoolchildren is related to industrialised and developed countries. The aim of this study was to investigate the prevalence of low back pain (LBP) and potential risk factors among schoolchildren and adolescents in a developing country, Iran. Methods: A cross-sectional study was conducted among 1611 Iranian schoolchildren aged 11-14 years. A self-complete questionnaire was used to assess LBP prevalence, physical leisure activities, school-related and psychosocial factors. Results: The prevalence of LBP was 34.3%. Female gender (odds ratio [OR] = 1.57, 95% CI:1.28-1.94), family member with back pain (OR = 1.82, 95% CI: 1.40-2.36), difficulty in viewing the (black)board (OR = 1.50, 95% CI: 1.13-1.99), too much homework (OR = 1.47, 95% CI:1.09-1.99), time spend carrying a schoolbag (min/d) (OR = 1.37, 95% CI: 1.01-1.85), and psychosocial factors (emotional symptoms) (OR = 2.28, 95% CI: 1.54-3.39) were independently associated with LBP. Physical activity, having a job, watching television, using a computer, playing games and schoolbag weight had no effect. Conclusion: It can be concluded that both physical and psychosocial factors influenced the risk for LBP, but emotional symptoms had a stronger association with LBP than physical factors. Knowledge about LBP in school children and adolescents could be important in assessment and treatment of such symptoms in this population. AU - Dianat, Iman AU - Alipour, Arezou AU - Asghari Jafarabadi, Mohammad DA - 2017 DO - 10.15171/hpp.2017.39 DP - PubMed IS - 4 J2 - Health Promot Perspect KW - Children Classroom furniture Musculoskeletal Psychological Schoolbag LA - eng PY - 2017 SN - 2228-6497 SP - 223-229 ST - Prevalence and risk factors of low back pain among school age children in Iran T2 - Health Promotion Perspectives TI - Prevalence and risk factors of low back pain among school age children in Iran UR - http://www.ncbi.nlm.nih.gov/pubmed/29085800 VL - 7 ID - 70 ER - TY - JOUR AB - Background: Schoolchildren usually use school bags to carry their school materials. Carrying heavy school bags can cause several problems such as musculoskeletal problems among schoolchildren. The aim of this study was to investigate the association between the weight of school bags and the occurrence of low back, shoulder and hand/wrist symptoms among primary school children. Method: This cross-sectional, descriptive-analytical study was conducted among a sample of 307 elementary school children in Tabriz, Iran. Data were collected using a questionnaire and from measurement of the school bag weight, body weight and height of each participant. Data were analysed using SPSS software. Results: The average load carried by schoolchildren was 2.9 kg, representing approximately 10% of the children's body weight. Girls and lower grade children carried a greater percentage of their body weights. Approximately 86% of the children reported some kind of musculoskeletal symptoms. The occurrence of shoulder, wrists/hands, and low back pain among schoolchildren was 70%, 18.5% and 8.7%, respectively. The results of binary logistic regression indicated that the school bag weight (expressed as a percentage of body weight) was only significantly associated with hand/wrist symptoms (P<0.05). Girls were more likely to complaint from low back pain than boys were. Age was significantly negatively associated with hand/wrist symptoms. Body mass index was also significantly associated with shoulder symptoms. Conclusion: The results indicate a high prevalence of musculoskeletal symptoms among elementary schoolchildren. Preventive measures and appropriate guidelines with regard to safe load carriage in schoolchildren are therefore needed to protect this age group. AN - WOS:000435872100008 AU - Dianat, I. AU - Javadivala, Z. AU - Allahverdipour, H. DO - 10.5681/hpp.2011.008 IS - 1 N1 - Dianat, Iman Javadivala, Zeynab Allahverdipour, Hamid Javadivala, Zeinab/Y-2655-2019 Javadivala, Zeinab/0000-0003-0231-8189 PY - 2011 SN - 2228-6497 SP - 76-85 ST - School Bag Weight and the Occurrence of Shoulder, Hand/Wrist and Low Back Symptoms among Iranian Elementary Schoolchildren T2 - Health Promotion Perspectives TI - School Bag Weight and the Occurrence of Shoulder, Hand/Wrist and Low Back Symptoms among Iranian Elementary Schoolchildren UR - ://WOS:000435872100008 VL - 1 ID - 2518 ER - TY - JOUR AB - OBJECTIVE: To evaluate if perceived occupational factors are associated with insufficient free-time physical activity in Brazilian public school teachers. METHODS: The relationship between insufficient physical activity (< 150 minutes/week) and variables related to work was analyzed in 978 elementary and high school teachers calculating the prevalence ratio (PR) and 95% confidence interval (95%CI) in Poisson regression models, adjusted for sociodemographic and health variables. RESULTS: The prevalence of insufficient physical activity was 71.9%, and this condition was associated independently with the perception of bad or regular balance between personal and professional life (PR = 1.09; 95%CI 1.01-1.18), perception that standing time affects the work (PR = 1.16; 95%CI 1.01-1.34), low or very low perception of current ability for the physical requirements of work (PR = 1.21; 95%CI 1.08-1.35), and temporary employment contract (PR = 1.13; 95%CI 1.03-1.25). The teaching of physical education was associated with lower prevalence of insufficient physical activity (PR = 0.78; 95%CI 0.64-0.95). CONCLUSIONS: The perception of adverse working conditions is associated with increased prevalence of insufficient physical activity in teachers and should be considered for the promotion of physical activity in this population. OBJETIVO: Analisar se fatores ocupacionais percebidos estão associados à atividade física insuficiente no tempo livre em professores de escolas públicas. MÉTODOS: A relação entre atividade física insuficiente (< 150 minutos/semana) e variáveis relacionadas ao trabalho foi analisada em 978 professores do ensino fundamental e médio mediante o cálculo da razão de prevalência (RP) e intervalo de confiança de 95% (IC95%) em modelos de regressão de Poisson, ajustados por variáveis sociodemográficas e de saúde. RESULTADOS: A prevalência de atividade física insuficiente foi de 71,9%, e essa condição associou-se de maneira independente com percepção de equilíbrio entre vida pessoal e profissional ruim ou regular (RP = 1,09; IC95% 1,01-1,18), percepção de que o tempo de permanência em pé afeta o trabalho (RP = 1,16; IC95% 1,01-1,34), percepção de capacidade atual para as exigências físicas do trabalho baixa ou muito baixa (RP = 1,21; IC95% 1,08-1,35) e contrato de trabalho temporário (RP = 1,13; IC95% 1,03-1,25). Ministrar disciplina de educação física associou-se com menor prevalência de atividade física insuficiente (RP = 0,78; IC95% 0,64-0,95). CONCLUSÕES: A percepção de condições de trabalho negativas associa-se à maior prevalência de atividade física insuficiente em professores e devem ser consideradas para a promoção de atividade física nessa população. Publisher: Abstract available from the publisher. por AD - Programa de Pós-Graduação em Saúde Coletiva. Universidade Estadual de Londrina. Londrina, PR, Brasil. Departamento de Educação Física. Universidade Estadual de Londrina. Londrina, PR, Brasil. Departamento de Saúde Coletiva. Universidade Estadual de Londrina. Londrina, PR, Brasil. AN - 28746571 AU - Dias, D. F. AU - Loch, M. R. AU - González, A. D. AU - Andrade, S. M. AU - Mesas, A. E. C2 - PMC5510795 DA - Jul 20 DO - 10.1590/s1518-8787.2017051006217 DP - NLM ET - 2017/07/27 KW - Adult Age Distribution Age Factors Brazil/epidemiology Chronic Pain/epidemiology/etiology Cross-Sectional Studies Exercise/*physiology Female Humans Male Middle Aged Occupational Diseases/*epidemiology/*etiology/physiopathology Reference Values School Teachers/*statistics & numerical data *Sedentary Behavior Sex Distribution Socioeconomic Factors Surveys and Questionnaires Time Factors Workload/*statistics & numerical data LA - eng por N1 - 1518-8787 Dias, Douglas Fernando Loch, Mathias Roberto González, Alberto Durán Andrade, Selma Maffei de Mesas, Arthur Eumann Journal Article Observational Study Rev Saude Publica. 2017 Jul 20;51:68. doi: 10.1590/S1518-8787.2017051006217. PY - 2017 SN - 0034-8910 (Print) 0034-8910 SP - 68 ST - Insufficient free-time physical activity and occupational factors in Brazilian public school teachers T2 - Rev Saude Publica TI - Insufficient free-time physical activity and occupational factors in Brazilian public school teachers VL - 51 ID - 3692 ER - TY - JOUR AB - OBJECTIVE: To assess the influence of an educational intervention in reducing «fear-avoidance» (FA) and «pain catastrophising» (CAT) in a population with unspecific chronic low back pain (UCLBP), attending physiotherapy in Primary Health Care. A pragmatic quasi-experimental study was conducted in Health Centres of a Costa del Sol Health District. DESIGN: Quasi-experimental study. SETTING: Primary Health Care physiotherapy Back Schools in Health Centres of a Costa del Sol Health District. PARTICIPANTS: The selection criteria were: UCLBP; 18-65years; understanding of the Spanish language; absence of parallel educational interventions; absence of red flags; not showing cognitive impairment or fibromyalgia; absence of thoracic-lumbar surgery, and exercise tolerance. INTERVENTIONS: The control group received the usual Back Schools program. The experimental group also received a written document for home reading, plus the subsequent sharing, clarifying doubts, and beliefs and goals restructuring during the development of the sessions. Both interventions lasted about 280minutes (7 sessions×40min). RESULTS: The main variables included FA and CAT. Pain and disability were also assessed. Some «demographic» and «related disorder» variables were considered in the analysis. Statistically significant differences were observed in the experimental group versus control, in the variation of FA -14 (-25.5; 0) vs -4 (-13; 0) (P=.009), and CAT -9 (-18; -4) vs -4,5 (-8.25; 0) (P=.000), were observed. Also differences in disability (P=.046), but not in pain (P=.280). CONCLUSIONS: These results should be considered in light of possible limits imposed by the study. Its pragmatic nature would allow a potential transfer to usual care. Publisher: Abstract available from the publisher. spa AD - Distrito Sanitario Costa del Sol, Servicio Andaluz de Salud, Junta de Andalucía, Málaga, España. Electronic address: juanlu1x2@hotmail.com. U.G.C. Las Lagunas, Unidad de Fisioterapia, Distrito Sanitario Costa del Sol, Servicio Andaluz de Salud, Junta de Andalucía, Mijas-Costa, Málaga, España; Área de conocimiento de Fisioterapia, Departamento de Psiquiatría y Fisioterapia, Facultad de Ciencias de la Salud, Universidad de Málaga, Málaga, España. Unidad AME (IBIMA-FIMABIS), Málaga, España. U.G.C. Las Albarizas, Unidad de Fisioterapia, Distrito Sanitario Costa del Sol, Servicio Andaluz de Salud, Junta de Andalucía, Mijas-Costa, Málaga, España. AN - 26724987 AU - Díaz-Cerrillo, J. L. AU - Rondón-Ramos, A. AU - Pérez-González, R. AU - Clavero-Cano, S. C2 - PMC6877809 DA - Aug-Sep DO - 10.1016/j.aprim.2015.10.007 DP - NLM ET - 2016/01/05 IS - 7 KW - Adolescent Adult Aged Cognition *Cognitive Behavioral Therapy Female Humans Low Back Pain/*therapy Male Medicine Middle Aged Physical Therapy Modalities Primary Health Care Young Adult Atención primaria Catastrofismo Catastrophism Educación en salud Fear Fisioterapia Health education Low back pain Lumbalgia Miedo LA - spa N1 - 1578-1275 Díaz-Cerrillo, Juan Luis Rondón-Ramos, Antonio Pérez-González, Rita Clavero-Cano, Susana Clinical Trial Journal Article Aten Primaria. 2016 Aug-Sep;48(7):440-8. doi: 10.1016/j.aprim.2015.10.007. Epub 2015 Dec 24. OP - Ensayo no aleatorizado de una intervención educativa basada en principios cognitivo-conductuales para pacientes con lumbalgia crónica inespecífica atendidos en fisioterapia de atención primaria. PY - 2016 SN - 0212-6567 (Print) 0212-6567 SP - 440-8 ST - [Non-randomised trial of an educational intervention based on cognitive-behavioural principles for patients with chronic low back pain attended in Primary Care Physiotherapy] T2 - Aten Primaria TI - [Non-randomised trial of an educational intervention based on cognitive-behavioural principles for patients with chronic low back pain attended in Primary Care Physiotherapy] VL - 48 ID - 3890 ER - TY - JOUR AB - BACKGROUND: Persistent low back pain in the young remains a significant diagnostic and treatment challenge for clinicians. Traditionally, chronic low back pain in this population has been attributed to either serious undetected pathology or psychosocial etiologies. This assumption may be incorrect because patients in this population may have underlying juvenile degenerative disc disease (JDDD), an important pathological diagnosis in the adult population. PURPOSE: The purpose of this study is to report the presentation, radiographic findings, diagnosis, and treatment modalities of juvenile patients presenting with persistent low back pain for greater then 6 months. STUDY DESIGN: This is a retrospective review of patients less than 21 years old referred to a spine specialty practice with persistent low back pain. PATIENT SAMPLE: The charts of 1,877 patients less than 21 years old referred to a spine specialty practice for the evaluation of spinal problems. OUTCOME MEASURES: Magnetic resonance images (MRI) were obtained and reviewed by a neuroradiologist and two orthopedic surgeons. METHODS: Patients younger than 21 years old with persistent low back pain for greater that 6 months were identified. Patients with scoliosis, Scheuermann's kyphosis, spondylolisthesis, fracture, tumor, and metabolic bone disease were excluded. Standard demographic information, relevant medical history and physical examination findings were collected. Patients were evaluated with an MRI of their spines to detect any potential underlying pathology. The success of various treatment modalities used was reviewed. The findings of this study were correlated to those of the available literature following a thorough review. RESULTS: Seventy-six patients (34 males, 42 females) with degenerative disc disease were identified on MRI. The mean age was 17.1 years (range 11.5-21.0) with a mean body mass index (BMI) of 24.5 (range 17.7-35.4). Thirty-one had associated radiculopathy. There was I I smokers, 20 involved in athletics, 17 with co-morbidities, and 9 with a BMI greater than 30. A distinct subgroup of 13 patients with multilevel concurrent spinal stenosis was documented. Four of this subgroup required surgical intervention for severe radicular or claudication symptoms. The majority of JDDD patients were successfully treated with nonoperative modalities. CONCLUSION: The findings of this study question whether lumbosacral degenerative disc disease, commonly thought to exist only in an older population, in fact begins earlier in selected patients. Our study confirms the findings of others that there is a definite population of juveniles that present with chronic low back pain who have degenerative disc disease identified on MRI. Within this population is a subgroup of patients with concurrent congenital spinal stenosis. Most patients with JDDD appear to be well managed by traditional nonoperative treatment modalities. (c) 2007 Elsevier Inc. All rights reserved. AN - WOS:000251490100012 AU - Dimar, J. R. AU - Glassman, S. D. AU - Carreon, L. Y. DA - May-Jun DO - 10.1016/j.spinee.2006.03.008 IS - 3 N1 - Dimar, John R. Glassman, Steven D. Carreon, Leah Y. Carreon, Leah/AAM-6577-2021 Carreon, Leah/0000-0002-7685-9036 1878-1632 PY - 2007 SN - 1529-9430 SP - 332-337 ST - Juvenile degenerative disc disease: a report of 76 cases identified by magnetic resonance imaging T2 - Spine Journal TI - Juvenile degenerative disc disease: a report of 76 cases identified by magnetic resonance imaging UR - ://WOS:000251490100012 VL - 7 ID - 2691 ER - TY - JOUR AB - Pain experiences, learning, and genetic factors have been proposed to shape attentional and emotional processes related to pain. We aimed at investigating whether a singular major pain experience also changes cognitive-emotional processing. The influence of acute postoperative pain after cosmetic surgery of the thorax was tested in 80 preoperatively pain-free male individuals. Acute pain was measured as independent variable during the first week postsurgery by pain intensity ratings and the requested analgesic boluses (Patient-Controlled Epidural Analgesia (PCEA)). Pain catastrophizing (Pain Catastrophizing Scale (PCS)), pain anxiety (Pain Anxiety and Symptom Scale (PASS)), pain hypervigilance (Pain Vigilance and Awareness Questionnaire (PVAQ)), and attentional biases to emotionally loaded stimuli (including pain) in a dot-probe task were assessed 1 week, 3 months, and 6 months postsurgery as dependent variables. Hierarchical regression analyses were performed to test whether the 2 acute pain parameters can predict these cognitive-emotional variables. As a rigorous test, significant prediction was required in addition to the prediction of the dependent variables by themselves with lag-1. Acute pain (mainly the pain ratings) appeared to be a significant predictor for PCS, PASS, and PVAQ 1 week after surgery (deltaR(2) = [8.7% to 11.3%]). In contrast, the attentional biases in the dot-probe task could not be predicted by the pain ratings. The levels of pain catastrophizing and pain hypervigilance increased in the acute phase after surgery when influenced by acute pain and declined, along with pain anxiety, during the next 3 months. In conclusion, a one-time intense pain experience, such as acute postoperative pain, appeared to produce at least short-lived changes in the attentional and emotional processing of pain. (C) 2013 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved. AN - WOS:000327596200024 AU - Dimova, V. AU - Horn, C. AU - Parthum, A. AU - Kunz, M. AU - Schofer, D. AU - Carbon, R. AU - Griessinger, N. AU - Sittl, R. AU - Lautenbacher, S. DA - Dec DO - 10.1016/j.pain.2013.08.005 IS - 12 N1 - Dimova, Violeta Horn, Claudia Parthum, Andreas Kunz, Miriam Schoefer, Dorothea Carbon, Roman Griessinger, Norbert Sittl, Reinhard Lautenbacher, Stefan Kunz, Miriam/P-8160-2016 Kunz, Miriam/0000-0002-0740-6738; , Stefan/0000-0002-2829-347X 1872-6623 PY - 2013 SN - 0304-3959 SP - 2737-2744 ST - Does severe acute pain provoke lasting changes in attentional and emotional mechanisms of pain-related processing? A longitudinal study T2 - Pain TI - Does severe acute pain provoke lasting changes in attentional and emotional mechanisms of pain-related processing? A longitudinal study UR - ://WOS:000327596200024 VL - 154 ID - 2334 ER - TY - JOUR AB - BACKGROUND: A substantial number of children experience spinal pain, that is, back and/or neck pain. Today, no 'gold-standard' treatment for spinal pain in children exists, but manipulative therapy is increasingly being used in spite of a lack of evidence of its effectiveness. This study investigates the effectiveness of adding manipulative therapy to other conservative care for spinal pain in a school-based cohort of Danish children aged 9-15 years. METHODS AND FINDINGS: The design was a two-arm pragmatic randomised controlled trial, nested in a longitudinal open cohort study in Danish public schools. 238 children from 13 public schools were randomised individually from February 2012 to April 2014. A text message system and clinical examinations were used for data collection. Interventions included either (1) advice, exercises and soft-tissue treatment or (2) advice, exercises and soft-tissue treatment plus manipulative therapy. The primary outcome was number of recurrences of spinal pain. Secondary outcomes were duration of spinal pain, change in pain intensity and Global Perceived Effect.We found no significant difference between groups in the primary outcome (control group median 1 (IQR 1-3) and intervention group 2 (IQR 0-4), p=0.07). Children in the group receiving manipulative therapy reported a higher Global Perceived Effect: OR 2.22, (95% CI 1.19 to 4.15). No adverse events were reported. Main limitations are the potential discrepancy between parental and child reporting and that the study population may not be comparable to a normal care-seeking population. CONCLUSIONS: Adding manipulative therapy to other conservative care in school children with spinal pain did not result in fewer recurrent episodes. The choice of treatment-if any-for spinal pain in children therefore relies on personal preferences, and could include conservative care with and without manipulative therapy. Participants in this trial may differ from a normal care-seeking population. TRIAL REGISTRATION NUMBER: NCT01504698; Results. AU - Dissing, Kristina Boe AU - Hartvigsen, Jan AU - Wedderkopp, Niels AU - Hestbæk, Lise DA - 2018/09/10/ DO - 10.1136/bmjopen-2017-021358 DP - PubMed IS - 9 J2 - BMJ Open KW - Adolescent back pain Child clinical trials Conservative Treatment Denmark evidence based practice Exercise Therapy Female Humans Male manipulative therapy Musculoskeletal Manipulations Neck Pain paediatrics Pain Measurement randomized controlled trial Recurrence Schools Single-Blind Method LA - eng PY - 2018 SN - 2044-6055 SP - e021358 ST - Conservative care with or without manipulative therapy in the management of back and/or neck pain in Danish children aged 9-15 T2 - BMJ open TI - Conservative care with or without manipulative therapy in the management of back and/or neck pain in Danish children aged 9-15: a randomised controlled trial nested in a school-based cohort UR - http://www.ncbi.nlm.nih.gov/pubmed/30206079 VL - 8 ID - 64 ER - TY - JOUR AB - BACKGROUND: Spinal pain in children and adolescents is a common condition, usually transitory, but the picture of spinal pain still needs elucidation, mainly due to variation in measurement methods. The aim of this study was to describe the occurrence of spinal pain in 8-15 year-old Danish school children, over a 3-year period. Specifically determining the characteristics of spinal pain in terms of frequency and duration. METHODS: The study was a 3-year prospective longitudinal cohort study including 1400 school children. The outcomes were based on weekly text messages (SMS) to the parents inquiring about the child's musculoskeletal pain, and on clinical data from examinations of the children. RESULTS: The 3-year prevalence was 55%. The prevalence was 29%, 33% and 31% for each of the three study years respectively, and increased statistically significantly with age, especially for lumbopelvic pain. Most children had few and short-lasting episodes with spinal pain, but more than one out of five children had three or more episodes during a study year and 17% of all episodes lasted for more than 4 weeks. CONCLUSION: This study demonstrates that spinal pain is a substantial problem. Most episodes are brief, but there are a vast number of children with frequent and long-lasting episodes of spinal pain indicating a need for action regarding evidence-based prevention and management. AU - Dissing, Kristina Boe AU - Hestbæk, Lise AU - Hartvigsen, Jan AU - Williams, Christopher AU - Kamper, Steven AU - Boyle, Eleanor AU - Wedderkopp, Niels DA - 2017/03/27/ DO - 10.1186/s12891-017-1424-5 DP - PubMed IS - 1 J2 - BMC Musculoskelet Disord KW - Adolescent Adolescents Age Factors Back Pain Child Children Denmark Female Follow-Up Studies Humans Male Musculoskeletal Pain Pain Measurement Parents Prevalence Prospective Studies Spinal pain Surveys and Questionnaires Time Factors LA - eng PY - 2017 SN - 1471-2474 SP - 67 ST - Spinal pain in Danish school children - how often and how long? T2 - BMC musculoskeletal disorders TI - Spinal pain in Danish school children - how often and how long? The CHAMPS Study-DK UR - http://www.ncbi.nlm.nih.gov/pubmed/28343450 VL - 18 ID - 74 ER - TY - JOUR AB - BACKGROUND: A prospective study controlled for sex and age was conducted evaluating the success of a 3-week inpatient pain therapy after 3, 6 and 12 months for 200 children and adolescents severely disabled due to chronic pain. METHODS: The following validated German questionnaires were used: pain questionnaire (DSF-K/J/E), pain coping inventory (PPCI-R), anxiety questionnaire (AFS) and depression questionnaire (DIKJ). After an intention-to-treat analysis unifactorial und multifactorial variance analyses were conducted. A significance level of p<0.01 was used. RESULTS: Durable improvements were observed for average pain intensity, pain disability, days absent from school, depression and for passive and interaction-based pain coping strategies 3 months after finishing inpatient pain therapy. On the other hand general anxiety and school aversion were only reduced at 6 and 12 months, respectively. Girls reported more pain in general and during follow-up. Younger children relied in general more on others when dealing with their pain. CONCLUSION: An inpatient pain therapy can help children and adolescents severely disabled due to chronic pain not only in the short term but also in the long term. AD - Vodafone Stiftungsinstitut und Lehrstuhl für Kinderschmerztherapie und Pädiatrische Palliativmedizin, Vestische Kinder- und Jugendklinik Datteln, Universität Witten/Herdecke, Datteln. m.dobe@kinderklinik-datteln.de AN - 21594660 AU - Dobe, M. AU - Hechler, T. AU - Behlert, J. AU - Kosfelder, J. AU - Zernikow, B. DA - Aug DO - 10.1007/s00482-011-1051-2 DP - NLM ET - 2011/05/20 IS - 4 KW - Adaptation, Psychological Adolescent Anxiety/psychology/therapy Child Chronic Pain/psychology/*therapy Combined Modality Therapy Cooperative Behavior Depression/psychology/therapy *Disability Evaluation Follow-Up Studies Germany *Hospitalization Humans Interdisciplinary Communication Length of Stay Pain Measurement/psychology Patient Care Team Phobic Disorders/psychology/therapy Prospective Studies Sex Factors Surveys and Questionnaires LA - ger N1 - 1432-2129 Dobe, M Hechler, T Behlert, J Kosfelder, J Zernikow, B Controlled Clinical Trial English Abstract Journal Article Germany Schmerz. 2011 Aug;25(4):411-22. doi: 10.1007/s00482-011-1051-2. OP - Schmerztherapie bei Chronisch Schmerzkranken, Schwer Beeinträchtigten Kindern und Jugendlichen: Langzeiterfolge einer 3-Wöchigen Stationären Schmerztherapie. PY - 2011 SN - 0932-433x SP - 411-22 ST - [Pain therapy with children and adolescents severely disabled due to chronic pain: long-term outcome after inpatient pain therapy] T2 - Schmerz TI - [Pain therapy with children and adolescents severely disabled due to chronic pain: long-term outcome after inpatient pain therapy] VL - 25 ID - 3289 ER - TY - BOOK A2 - Dobe, M. A2 - Zernikow, B. AB - For many children experiencing chronic pain, effective treatment is possible in an outpatient setting. However, for children with a pain disorder that severely affects the patient's and his/her family's life (frequently missing school; social withdrawal), an inpatient interdisciplinary pain treatment is indicated. In this chapter, we first discuss the criteria used to determine the need and usefulness of inpatient pain treatment, then we discuss contraindications. AN - WOS:000550989700009 AU - Dobe, M. AU - Zernikow, B. DO - 10.1007/978-3-030-19201-3_5 N1 - Dobe, Michael Zernikow, Boris PY - 2019 SN - 978-3-030-19201-3; 978-3-030-19200-6 SP - 77-80 ST - When to Decide on In- or Outpatient Pain Treatment? T2 - Practical Treatment Options for Chronic Pain in Children and Adolescents: An Interdisciplinary Therapy Manual, 2nd Edition TI - When to Decide on In- or Outpatient Pain Treatment? UR - ://WOS:000550989700009 ID - 1962 ER - TY - JOUR AB - Children born very prematurely (< or =32 weeks) often exhibit visual-perceptual difficulties at school-age, even in the absence of major neurological impairment. The alterations in functional brain activity that give rise to such problems, as well as the relationship between adverse neonatal experience and neurodevelopment, remain poorly understood. Repeated procedural pain-related stress during neonatal intensive care has been proposed to contribute to altered neurocognitive development in these children. Due to critical periods in the development of thalamocortical systems, the immature brain of infants born at extremely low gestational age (ELGA; < or =28 weeks) may have heightened vulnerability to neonatal pain. In a cohort of school-age children followed since birth we assessed relations between functional brain activity measured using magnetoencephalogragy (MEG), visual-perceptual abilities and cumulative neonatal pain. We demonstrated alterations in the spectral structure of spontaneous cortical oscillatory activity in ELGA children at school-age. Cumulative neonatal pain-related stress was associated with changes in background cortical rhythmicity in these children, and these alterations in spontaneous brain oscillations were negatively correlated with visual-perceptual abilities at school-age, and were not driven by potentially confounding neonatal variables. These findings provide the first evidence linking neonatal pain-related stress, the development of functional brain activity, and school-age cognitive outcome in these vulnerable children. AU - Doesburg, Sam M. AU - Chau, Cecil M. AU - Cheung, Teresa P. L. AU - Moiseev, Alexander AU - Ribary, Urs AU - Herdman, Anthony T. AU - Miller, Steven P. AU - Cepeda, Ivan L. AU - Synnes, Anne AU - Grunau, Ruth E. DA - 2013/10// DO - 10.1016/j.pain.2013.04.009 DP - PubMed IS - 10 J2 - Pain KW - Child Child development Cognition Cognitive outcome Development Female Gestational Age Humans Infant, Extremely Low Birth Weight Infant, Extremely Premature Infant, Newborn Infant, Premature Longitudinal Studies Magnetoencephalography Male Neonatal pain Neural oscillation Pain Pain Measurement Perception Population Pregnancy Prematurity Preterm Resting-state Spontaneous brain activity Stress, Psychological Visual Cortex Visual perception LA - eng PY - 2013 SN - 1872-6623 SP - 1946-1952 ST - Neonatal pain-related stress, functional cortical activity and visual-perceptual abilities in school-age children born at extremely low gestational age T2 - Pain TI - Neonatal pain-related stress, functional cortical activity and visual-perceptual abilities in school-age children born at extremely low gestational age UR - http://www.ncbi.nlm.nih.gov/pubmed/23711638 VL - 154 ID - 90 ER - TY - JOUR AB - Resting cortical activity is characterized by a distinct spectral peak in the alpha frequency range. Slowing of this oscillatory peak toward the upper theta-band has been associated with a variety of neurological and neuropsychiatric conditions and has been attributed to altered thalamocortical dynamics. Children born very preterm exhibit altered development of thalamocortical systems. To test the hypothesis that peak oscillatory frequency is slowed in children born very preterm, we recorded resting magnetoencephalography (MEG) from school age children born very preterm (<= 32 wk gestation) without major intellectual or neurological impairment and age-matched full-term controls. Very preterm children exhibit a slowing of peak frequency toward the theta-band over bilateral frontal cortex, together with reduced alpha-band power over bilateral frontal and temporal cortex, suggesting that mildly dysrhythmic thalamocortical interactions may contribute to altered spontaneous cortical activity in children born very preterm. (Pediatr Res 70: 171-175, 2011) AN - WOS:000292949400010 AU - Doesburg, S. M. AU - Ribary, U. AU - Herdman, A. T. AU - Moiseev, A. AU - Cheung, T. AU - Miller, S. P. AU - Poskitt, K. J. AU - Weinberg, H. AU - Whitfield, M. F. AU - Synnes, A. AU - Grunau, R. E. DA - Aug DO - 10.1203/PDR.0b013e3182225a9e IS - 2 N1 - Doesburg, Sam M. Ribary, Urs Herdman, Anthony T. Moiseev, Alexander Cheung, Teresa Miller, Steven P. Poskitt, Kenneth J. Weinberg, Hal Whitfield, Michael F. Synnes, Anne Grunau, Ruth E. Miller, Steven/0000-0001-9102-9105; Ribary, Urs/0000-0002-1182-8052 PY - 2011 SN - 0031-3998 SP - 171-175 ST - Magnetoencephalography Reveals Slowing of Resting Peak Oscillatory Frequency in Children Born Very Preterm T2 - Pediatric Research TI - Magnetoencephalography Reveals Slowing of Resting Peak Oscillatory Frequency in Children Born Very Preterm UR - ://WOS:000292949400010 VL - 70 ID - 2484 ER - TY - JOUR AB - STUDY DESIGN: Cross-sectional baseline data set on the sagittal standing posture of 1196 adolescents. OBJECTIVE: To describe and quantify common variations in the sagittal standing alignment in boys and girls who are in the same phase of growth and to explore the association between habitual standing posture and measures for spinal pain. SUMMARY OF BACKGROUND DATA: Data on postural characteristics and spinal pain measures in adolescence are sparse, especially when somatic and biological maturity status is to be considered. Our understanding of the relationship between standing posture in the sagittal plane and spinal pain is also deficient. METHODS: A total of 639 boys (age [mean ± SD], 12.6 ± 0.54 yr) and 557 girls (10.6 ± 0.47 yr), with predicted years from peak height velocity (PHV) being 1.2 ± 0.71 and 1.2 ± 0.59 pre-PHV, respectively, were studied. Postural examination included the assessment of global alignment and local spinopelvic characteristics, using post hoc analyses of digital images and direct body measurements (palpation, digital inclinometry, and wheeled accelerometry). Spinal pain experience was assessed by questionnaire. RESULTS: A wide interindividual variation in sagittal posture characteristics was observed. Logistic regression analyses yielded global alignment parameters to be associated with low back pain (lifetime prevalence), neck pain (lifetime prevalence, 1-mo prevalence, and doctor visit), and thoracic spine pain (doctor visit) outcome measures. None of the included local spinopelvic parameters could be identified as an associated factor with measures of spinal pain. CONCLUSION: The orientation of gross body segments with respect to the gravity line seems superior to local spinopelvic features in terms of clinical importance, at least in the current pre-PHV cohort. Opportunities may exist for postural subgrouping strategies to begin with global alignment parameters in order to gain further insight into the relationship between sagittal alignment and the relative risk of developing spinal pain/seeking medical consultation for this pain. AU - Dolphens, Mieke AU - Cagnie, Barbara AU - Coorevits, Pascal AU - Vanderstraeten, Guy AU - Cardon, Greet AU - Dʼhooge, Roseline AU - Danneels, Lieven DA - 2012/09/01/ DO - 10.1097/BRS.0b013e3182408053 DP - PubMed IS - 19 J2 - Spine (Phila Pa 1976) KW - Adolescent Anthropometry Back Pain Belgium Body Height Child Cross-Sectional Studies Female Humans Male Neck Pain Office Visits Posture Prevalence School Health Services Sex Characteristics Spine Surveys and Questionnaires LA - eng PY - 2012 SN - 1528-1159 SP - 1657-1666 ST - Sagittal standing posture and its association with spinal pain T2 - Spine TI - Sagittal standing posture and its association with spinal pain: a school-based epidemiological study of 1196 Flemish adolescents before age at peak height velocity UR - http://www.ncbi.nlm.nih.gov/pubmed/22108378 VL - 37 ID - 100 ER - TY - JOUR AB - INTRODUCTION: Type 2 diabetes mellitus compromises physical, psychological, economic, and social life. OBJECTIVES: To identify and compare the quality of life, depression, functional performance, and physical activity in patients with type 2 diabetes mellitus who use insulin or not. METHODS: A observational, descriptive, cross-sectional, comparative study involving 100 patients (50 use insulin and 50 do not) from a Teaching Hospital. Questionnaires used: Identification and Socioeconomic Profile; SF-36; Hospital Anxiety and Depression Scale; Visual Analogue Scale for Pain; Canadian Occupational Performance Measure, and International Physical Activity Questionnaire. RESULTS: Sample composed predominantly by middle-aged, female, married, retired, and with incomplete elementary school individuals. There is impairment in all domains of quality of life, being more intense in functional capacity, physical limitations, pain, social aspects, limitation by emotional aspects, and mental health (P<0.05). There is a significant prevalence of anxiety or depressive symptoms in the groups, especially in those using insulin. However, the occurrence of the corresponding psychiatric disorders is unlikely (P<0.05). There was no significant difference in neuropathic pain between the groups (P=0.2296). Functional impairment is similar in both groups regarding self-care activities (P=0.4494) and productivity (P=0.5759), with a greater deterioration of leisure time in patients on insulin (P=0.0091). Most of them practice physical activity, predominantly walking, with no significant difference when comparing the groups (P>0.05), as well as in the other modalities. CONCLUSION: Insulinized patients present greater impairment of functional capacity and socialization, as well as greater neuropathic pain, anxiety, and depressive symptoms. AN - WOS:000510392000010 AU - dos Reis, A. C. AU - Cunha, M. V. AU - Bianchin, M. A. AU - Freitas, M. T. R. AU - Castiglioni, L. DA - Dec DO - 10.1590/1806-9282.65.12.1464 IS - 12 N1 - dos Reis, Ana Carolina Cunha, Milena Vizioli Bianchin, Maysa Alahmar Rui Freitas, Maristella Tonon Castiglioni, Lilian Castiglioni, Lilian/C-2687-2014 Castiglioni, Lilian/0000-0002-9999-2673; Reis, AlessanRSS/0000-0001-8486-7469; Dos Reis, Ana Carolina/0000-0001-9044-1317 1806-9282 PY - 2019 SP - 1464-1469 ST - Comparison of quality of life and functionality in type 2 diabetics with and without insulin T2 - Revista Da Associacao Medica Brasileira TI - Comparison of quality of life and functionality in type 2 diabetics with and without insulin UR - ://WOS:000510392000010 VL - 65 ID - 1865 ER - TY - JOUR AB - Psychogenic nonepileptic seizures is a complicated biopsychosocial disorder with significant morbidity and high cost in children's social, emotional, family, and academic functioning as well as health care service utilization. Misdiagnosis and diagnostic delay, resulting from both lack of access to approved standards for diagnosing and service providers comfortable with diagnosing and treating this disorder, affect prognosis. Treatment in close proximity to symptom onset is thought to provide the best chance for remission. AN - WOS:000418991100006 AU - Doss, J. L. AU - Plioplys, S. DA - Jan DO - 10.1016/j.chc.2017.08.007 IS - 1 N1 - Doss, Julia L. Plioplys, Sigita 1558-0490 PY - 2018 SN - 1056-4993 SP - 53-+ ST - Pediatric Psychogenic Nonepileptic Seizures A Concise Review T2 - Child and Adolescent Psychiatric Clinics of North America TI - Pediatric Psychogenic Nonepileptic Seizures A Concise Review UR - ://WOS:000418991100006 VL - 27 ID - 2055 ER - TY - JOUR AB - Musculoskeletal complaints are symptoms frequently encountered by the pediatric practitioner. The causes are most frequently minor traumatic events or joint and muscle stress; postinfectious joint complaints are also not uncommon. Musculoskeletal complaints of long duration or in multiple locations, however, require more in-depth examination. If a thorough work-up does not detect an underlying organic disorder, a chronic pain syndrome is the most probable cause. The two forms most frequently encountered are the chronic pain disorders of multiple body regions with somatic and psychological factors and the complex regional pain syndrome (CRPS), which differ substantially in their pathogenesis and clinical picture. Both require a specialized team for diagnostics and successful treatment and a multidisciplinary collaboration of physicians, nurses, physiotherapists, psychologist and other specialties in a multimodal setting is the key. AN - WOS:000436807400008 AU - Draheim, N. AU - Hugle, B. DA - Jul DO - 10.1007/s00112-018-0492-4 IS - 7 N1 - Draheim, N. Huegle, B. Hugle, Boris/AAN-3064-2020 1433-0474 PY - 2018 SN - 0026-9298 SP - 585-591 ST - Chronic musculoskeletal pain in children and adolescents T2 - Monatsschrift Kinderheilkunde TI - Chronic musculoskeletal pain in children and adolescents UR - ://WOS:000436807400008 VL - 166 ID - 2009 ER - TY - JOUR AB - OBJECTIVES: Describe the pattern of utilization and effectiveness of outpatient fracture pain medication. METHODS: A cross-sectional survey of caregivers of children with an isolated extremity fracture at a hospital-based pediatric orthopedic clinic during initial follow-up. RESULTS: Surveys were completed by 98 (79.2%) of 125 caregivers. Mean age of children was 9 years (range, 1-18 years). Fracture sites include arm (36%), wrist (24%), hand (6%), leg (14%), ankle (9%), and foot (6%). Pain was reported "worst" at the time of injury in 45.3% patients (95% confidence interval [CI], 35.0%-55.8%) and in the first 48 hours of injury in 30.5% patients (95% CI, 21.5%-40.8%). The most commonly used medications were ibuprofen 43.5% (95% CI, 34.4%-52.5%) and acetaminophen with codeine 26.1% (95% CI, 18.1%-34.1%). Mean duration of medication use was 3.2 days (95% CI, 2.8-3.6 days). The mean duration of functional limitations included 4.2 days (95% CI, 2.8-5.5 days) for playing, 2.6 days (95% CI, 1.7-3.4 days) for performing at school, 2.4 days (95% CI, 1.8-3.0 days) for sleeping, and 2.0 days (95% CI, 1.0-3.0 days) for eating. Mean days of work missed by caregivers was 1.6 (95% CI, 1.1-2.0 days), and days of school missed by children was 2.0 (95% CI, 1.6-2.3 days). Significantly more children with lower extremity fractures had functional limitation (P < 0.05). CONCLUSION: Most children with fractures have the "worst" pain in the first 48 hours after injury and used analgesia for 3 days after injury. There are noteworthy functional limitations for both children and their caregivers. Ibuprofen and acetaminophen with codeine are the analgesics most commonly used, with no clear superiority. AD - Pediatric Department, Children's Hospital of Wisconsin, Milwaukee, WI 53226, USA. adrendel@mail.mcw.edu AN - 16481924 AU - Drendel, A. L. AU - Lyon, R. AU - Bergholte, J. AU - Kim, M. K. DA - Feb DO - 10.1097/01.pec.0000199564.64264.f4 DP - NLM ET - 2006/02/17 IS - 2 KW - Adolescent *Ambulatory Care Analgesics/*therapeutic use Child Child, Preschool Cross-Sectional Studies Drug Utilization/statistics & numerical data Fractures, Bone/*complications Humans Infant Pain/*drug therapy/*etiology *Surveys and Questionnaires LA - eng N1 - 1535-1815 Drendel, Amy L Lyon, Roger Bergholte, Jo Kim, Michael K Journal Article United States Pediatr Emerg Care. 2006 Feb;22(2):94-9. doi: 10.1097/01.pec.0000199564.64264.f4. PY - 2006 SN - 0749-5161 SP - 94-9 ST - Outpatient pediatric pain management practices for fractures T2 - Pediatr Emerg Care TI - Outpatient pediatric pain management practices for fractures VL - 22 ID - 3887 ER - TY - JOUR AB - Our objective was to obtain national data of the estimated prevalence, sociodemographic relationships, and health impact of persons with functional gastrointestinal disorders. We surveyed a stratified probability random sample of U.S. householders selected from a data base of a national market firm (National Family Opinion, Inc.). Questions were asked about bowel symptoms, sociodemographic associations, work absenteeism, and physician visits. The sampling frame was constructed to be demographically similar to the U.S. householder population based on geographic region, age of householder, population density, household income, and household size. Of 8250 mailings, 5430 were returned suitable for analysis (66% response). The survey assessed the prevalence of 20 functional gastrointestinal syndromes based on fulfillment of multinational diagnostic (Rome) criteria. Additional variables studied included: demographic status, work absenteeism, health care use, employment status, family income, geographic area of residence, population density, and number of persons in household. For this sample, 69% reported having at least one of 20 functional gastrointestinal syndromes in the previous three months. The symptoms were attributed to four major anatomic regions: esophageal (42%), gastroduodenal (26%), bowel (44%), and anorectal (26%), with considerable overlap. Females reported greater frequencies of globus, functional dysphagia, irritable bowel syndrome, functional constipation, functional abdominal pain, functional biliary pain and dyschezia; males reported greater frequencies of aerophagia and functional bloating. Symptom reporting, except for incontinence, declines with age, and low income is associated with greater symptom reporting. The rate of work/school absenteeism and physician visits is increased for those having a functional gastrointestinal disorder. Furthermore, the greatest rates are associated with those having gross fecal incontinence and certain more painful functional gastrointestinal disorders such as chronic abdominal pain, biliary pain, functional dyspepsia and IBS. Preliminary information on the prevalence, socio-demographic features and health impact is provided for persons who fulfill diagnostic criteria for functional gastrointestinal disorders. AD - University of North Carolina, Division of Digestive Diseases, Chapel Hill 27599-7080. AN - 8359066 AU - Drossman, D. A. AU - Li, Z. AU - Andruzzi, E. AU - Temple, R. D. AU - Talley, N. J. AU - Thompson, W. G. AU - Whitehead, W. E. AU - Janssens, J. AU - Funch-Jensen, P. AU - Corazziari, E. AU - et al. DA - Sep DO - 10.1007/bf01303162 DP - NLM ET - 1993/09/01 IS - 9 KW - Absenteeism Adolescent Adult Aged Female Gastrointestinal Diseases/*epidemiology Health Surveys Humans Male Middle Aged Office Visits/statistics & numerical data Prevalence Sex Factors Socioeconomic Factors United States/epidemiology LA - eng N1 - Drossman, D A Li, Z Andruzzi, E Temple, R D Talley, N J Thompson, W G Whitehead, W E Janssens, J Funch-Jensen, P Corazziari, E Journal Article Research Support, Non-U.S. Gov't United States Dig Dis Sci. 1993 Sep;38(9):1569-80. doi: 10.1007/BF01303162. PY - 1993 SN - 0163-2116 (Print) 0163-2116 SP - 1569-80 ST - U.S. householder survey of functional gastrointestinal disorders. Prevalence, sociodemography, and health impact T2 - Dig Dis Sci TI - U.S. householder survey of functional gastrointestinal disorders. Prevalence, sociodemography, and health impact VL - 38 ID - 3633 ER - TY - JOUR AB - OBJECTIVE: Employers are playing an increasingly influential role in determining the scope and character of health coverage in the United States. This study compares the health and disability costs of depressive illness with those of four other chronic conditions among employees of a large U.S. corporation. METHOD: Data from the health and employee files of 15,153 employees of a major U.S. corporation who filed health claims in 1995 were examined. Analyses compared the mental health costs, medical costs, sick days, and total health and disability costs associated with depression and four other conditions: heart disease, diabetes, hypertension, and back problems. Regression models were used to control for demographic differences and job characteristics. RESULTS: Employees treated for depression incurred annual per capita health and disability costs of $5,415, significantly more than the cost for hypertension and comparable to the cost for the three other medical conditions. Employees with depressive illness plus any of the other conditions cost 1.7 times more than those with the comparison medical conditions alone. Depressive illness was associated with a mean of 9.86 annual sick days, significantly more than any of the other conditions. Depressed employees under the age of 40 years took 3.5 more annual sick days than those 40 years old or older. CONCLUSIONS: The cost of depression to employers, particularly the cost in lost work days, is as great or greater than the cost of many other common medical illnesses, and the combination of depressive and other common illnesses is particularly costly. The strong association between depressive illness and sick days in younger workers suggests that the impact of depression may increase as these workers age. AD - Department of Psychiatry, Yale University, West Haven, CT 06516, USA. benjamin.druss@yale.edu AN - 10910790 AU - Druss, B. G. AU - Rosenheck, R. A. AU - Sledge, W. H. DA - Aug DO - 10.1176/appi.ajp.157.8.1274 DP - NLM ET - 2000/07/27 IS - 8 KW - Absenteeism Adolescent Adult Aged Back Pain/economics Chronic Disease Comorbidity *Cost of Illness Depressive Disorder/*economics/epidemiology Diabetes Mellitus/economics Female Health Benefit Plans, Employee/*economics/statistics & numerical data Health Care Costs/*statistics & numerical data Heart Diseases/economics Humans Hypertension/economics Insurance, Disability/economics/statistics & numerical data Male Managed Care Programs Middle Aged Sick Leave/economics/statistics & numerical data LA - eng N1 - Druss, B G Rosenheck, R A Sledge, W H MH-01556/MH/NIMH NIH HHS/United States Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. United States Am J Psychiatry. 2000 Aug;157(8):1274-8. doi: 10.1176/appi.ajp.157.8.1274. PY - 2000 SN - 0002-953X (Print) 0002-953x SP - 1274-8 ST - Health and disability costs of depressive illness in a major U.S. corporation T2 - Am J Psychiatry TI - Health and disability costs of depressive illness in a major U.S. corporation VL - 157 ID - 3654 ER - TY - JOUR AB - Background: Pain among children is common, yet far less studied compared to that among adults. Little has been reported regarding various types of pain in a national community sample of German children. Methods: We examined pain experienced within a 3 month timeframe among 14,836 children and adolescents aged 3-17 years old, who participated in the German Health Interview and Examination Survey for Children and Adolescents (KiGGS) 2003-2006. Results: The 3-month prevalence rate was 71% for any pain, 47% for recurrent pain, 55% for pain at multiple (>= 2) locations and 27% for recurrent pain at multiple locations. Headache and abdominal pain were the most frequently reported (44.2%, 40.8%) either as recurrent (22.8%, 20.3%) or as the most bothersome pain (MBP) (19.6%, 14.7%). Children from immigrant vs. non-immigrant families and children from lower vs. upper social-class families showed significantly higher prevalence rates for tooth (14% vs. 10%), lower abdomen (10% vs. 7%), chest (9% vs. 7%), arm (9% vs. 6%) and eye pain (9% vs. 5%). Of children with repeated MBP, only 10% of them used medications or consulted a doctor about the pain 'often/always,' while the majority of them did not act at all. In general, older age groups, females, poor health status and urban residence were associated with pain in children. Conclusions: The rather high pain prevalence suggests pain among children may be a potential public health issue. Further studies are required to investigate the characteristics and correlational attributes of children suffering most frequently from pain and children from families with low socioeconomic status. (C) 2010 European Federation of International Association for the Study of Pain Chapters. Published by Elsevier Ltd. All rights reserved. AN - WOS:000291850200015 AU - Du, Y. AU - Knopf, H. AU - Zhuang, W. L. AU - Ellert, U. DA - Jul DO - 10.1016/j.ejpain.2010.11.009 IS - 6 N1 - Du, Yong Knopf, Hildtraud Zhuang, Wanli Ellert, Ute PY - 2011 SN - 1090-3801 SP - 649-657 ST - Pain perceived in a national community sample of German children and adolescents T2 - European Journal of Pain TI - Pain perceived in a national community sample of German children and adolescents UR - ://WOS:000291850200015 VL - 15 ID - 2486 ER - TY - JOUR AB - Background: Objective physical activity monitors (eg, accelerometers) have high rates of nonwear and do not provide contextual information about behavior. Objective: This study tested performance and value of a mobile phone app that combined objective and real-time self-report methods to measure physical activity using sensor-informed context-sensitive ecological momentary assessment (CS-EMA). Methods: The app was programmed to prompt CS-EMA surveys immediately after 3 types of events detected by the mobile phone's built-in motion sensor: (1) Activity (ie, mobile phone movement), (2) No-Activity (ie, mobile phone nonmovement), and (3) No-Data (ie, mobile phone or app powered off). In addition, the app triggered random (ie, signal-contingent) ecological momentary assessment (R-EMA) prompts (up to 7 per day). A sample of 39 ethnically diverse high school students in the United States (aged 14-18, 54% female) tested the app over 14 continuous days during nonschool time. Both CS-EMA and R-EMA prompts assessed activity type (eg, reading or doing homework, eating or drinking, sports or exercising) and contextual characteristics of the activity (eg, location, social company, purpose). Activity was also measured with a waist-worn Actigraph accelerometer. Results: The average CS-EMA + R-EMA prompt compliance and survey completion rates were 80.5% and 98.5%, respectively. More moderate-to-vigorous intensity physical activity was recorded by the waist-worn accelerometer in the 30 minutes before CS-EMA activity prompts (M=5.84 minutes) than CS-EMA No-Activity (M=1.11 minutes) and CS-EMA No-Data (M=0.76 minute) prompts (P's<.001). Participants were almost 5 times as likely to report going somewhere (ie, active or motorized transit) in the 30 minutes before CS-EMA Activity than R-EMA prompts (odds ratio=4.91, 95% confidence interval=2.16-11.12). Conclusions: Mobile phone apps using motion sensor-informed CS-EMA are acceptable among high school students and may be used to augment objective physical activity data collected from traditional waist-worn accelerometers. AN - WOS:000388495200053 AU - Dunton, G. F. AU - Dzubur, E. AU - Intille, S. C7 - e106 DA - Jun DO - 10.2196/jmir.5398 IS - 6 N1 - Dunton, Genevieve Fridlund Dzubur, Eldin Intille, Stephen PY - 2016 SN - 1438-8871 ST - Feasibility and Performance Test of a Real-Time Sensor-Informed Context-Sensitive Ecological Momentary Assessment to Capture Physical Activity T2 - Journal of Medical Internet Research TI - Feasibility and Performance Test of a Real-Time Sensor-Informed Context-Sensitive Ecological Momentary Assessment to Capture Physical Activity UR - ://WOS:000388495200053 VL - 18 ID - 2164 ER - TY - JOUR AB - Background Juvenile Fibromyalgia Syndrome (JFMS) is a chronic health condition characterized by widespread musculoskeletal pain and multiple tender points (TP). The objective of this study was to determine the prevalence of JFMS in the urban population of Samsun and to determine the impact of JFMS on depression symptoms, school performance and quality of life (QOL). Methods A cross-sectional study was conducted in 1109 children (mean age (14.8+/-2.0) years old). A questionnaire was applied to the children and a medical examination including TP was performed. Yunus and Masi's criteria were used for diagnosis of JFMS. The children with JFMS were compared with an age and sex matched non-JFMS group. Depression was assessed with Children's Depression Inventory (CDI) and QOL was evaluated with Pediatric Quality of Life Inventory 4.0 (PedsQL4.0). Results Sixty-one (5.5%) (13 boys and 48 girls) of 1109 children met the diagnostic criteria of JFMS. While PedsQL scores of children with JFMS were lower than the non-JFMS group for physical, emotional, social, school functioning and total score (P=0.001), CDI total score was higher in the JFMS group than in the non-JFMS group (P=0.001). The JFMS group reported more school absences (P=0.001) and the average school grade was lower in the JFMS group than in the non-JFMS group (P=0.03). Conclusion The prevalence of JFMS is high in school age children. Since JFMS is a common problem of childhood, early diagnosis and identification of the disorder and more comprehensive and successful treatment approaches with appropriate psychological assistance may prevent more complex and severe problems in adulthood. AN - WOS:000326426800020 AU - Durmaz, Y. AU - Alayli, G. AU - Canbaz, S. AU - Zahiroglu, Y. AU - Bilgici, A. AU - Ilhanli, I. AU - Kuru, O. DA - Oct DO - 10.3760/cma.j.issn.0366-6999.20130185 IS - 19 N1 - Durmaz, Yunus Alayli, Gamze Canbaz, Sevgi Zahiroglu, Yeliz Bilgici, Ayhan Ilhanli, Ilker Kuru, Omer ilhanli, ilker/H-1410-2014; Kuru, Omer/AAB-9931-2020; Canbaz, Sevgi/AAD-5192-2020 PY - 2013 SN - 0366-6999 SP - 3705-3711 ST - Prevalence of juvenile fibromyalgia syndrome in an urban population of Turkish adolescents: impact on depressive symptoms, quality of life and school performance T2 - Chinese Medical Journal TI - Prevalence of juvenile fibromyalgia syndrome in an urban population of Turkish adolescents: impact on depressive symptoms, quality of life and school performance UR - ://WOS:000326426800020 VL - 126 ID - 2341 ER - TY - JOUR AB - Primary headaches among children and adolescents have a substantial impact on quality of life, daily activities, social interaction, and school performance in combination with psychopathological symptoms. The main purpose of the present paper is to summarize clinical and epidemiological evidence for psychiatric comorbidity among children and adolescents with headaches, to describe how evidence in headache research suggest different pathways involved in the development and maintenance of these comorbid conditions, and finally suggest some elements professionals may find helpful to assess the scope of complaints, related functional impairment, and potential precipitating factors in planning of more targeted treatments. AN - WOS:000351517000005 AU - Dyb, G. AU - Stensland, S. AU - Zwart, J. A. C7 - 5 DA - Mar DO - 10.1007/s11916-015-0479-y IS - 3 N1 - Dyb, Grete Stensland, Synne Zwart, John-Anker 1534-3081 PY - 2015 SN - 1531-3433 ST - Psychiatric Comorbidity in Childhood and Adolescence Headache T2 - Current Pain and Headache Reports TI - Psychiatric Comorbidity in Childhood and Adolescence Headache UR - ://WOS:000351517000005 VL - 19 ID - 2246 ER - TY - JOUR AB - A survey of 569 young people with sickle cell disorder (SCD) in England has found such pupils miss considerable periods of time from school, typically in short periods of two or three days. One in eight has school absences equating to government-defined 'persistent absence'. Students with SCD report that they are not helped to catch up after these school absences. Half the children reported not being allowed to use the toilet when needed and not being allowed water in class; a third reported being made to take unsuitable exercise and being called lazy when tired. Children perceived both physical environment (temperature, school furniture) and social environment (being upset by teachers or other pupils) as triggers to episodes of their illness. Policy initiatives on school absences; preventive measures to ensure maintenance of good health; and measures to prevent perceived social attitudes precipitating ill health would also support children with other chronic illnesses at school. AN - WOS:000273721700008 AU - Dyson, S. M. AU - Abuateya, H. AU - Atkin, K. AU - Culley, L. AU - Dyson, S. E. AU - Rowley, D. AU - Sickle Cell Educ, Sced Grp C7 - Pii 910703721 DO - 10.1080/01411920902878941 IS - 1 N1 - Dyson, Simon Martin Abuateya, Hala Atkin, Karl Culley, Lorraine Dyson, Sue Elizabeth Rowley, Dave Dyson, Simon/0000-0002-4735-2527 1469-3518 PY - 2010 SN - 0141-1926 SP - 125-142 ST - Reported school experiences of young people living with sickle cell disorder in England T2 - British Educational Research Journal TI - Reported school experiences of young people living with sickle cell disorder in England UR - ://WOS:000273721700008 VL - 36 ID - 2571 ER - TY - JOUR AB - The characteristics of five 11- to 15-year-old patients with somatic symptoms and alexithymia in conjunction with psychological distress are reported. The findings are compared with the existing literature. Preceding somatic disorders and difficulties at school and in peer relationships were found. Family violence was evident in two cases. We postulate that the developmental tasks of adolescence were complicated by the threat of disability, disease, and death. The parents were incapable of expressing their feelings either in general or because of their recent traumatic experiences. Our findings suggest that unbearable emotions often precede the combination of preadolescent and adolescent alexithymia and somatization in clinically relevant cases. AN - WOS:000173019200003 AU - Ebeling, H. AU - Moilanen, I. AU - Linna, S. L. AU - Rasanen, E. DO - 10.1080/08039480152693273 IS - 6 N1 - Ebeling, H Moilanen, I Linna, SL Rasanen, E PY - 2001 SN - 0803-9488 SP - 387-393 ST - Somatically expressed psychological distress and alexithymia in adolescence - reflecting unbearable emotions? T2 - Nordic Journal of Psychiatry TI - Somatically expressed psychological distress and alexithymia in adolescence - reflecting unbearable emotions? UR - ://WOS:000173019200003 VL - 55 ID - 2860 ER - TY - JOUR AB - Background: Pain is common in otherwise healthy adolescents. In recent years widespread musculoskeletal pain, in contrast to single site pain, and associating factors has been emphasized. Musculoskeletal pain has not been examined in Arctic indigenous adolescents. The aim of this study was to explore the prevalence of widespread musculoskeletal pain and its association with psychosocial factors, with emphasis on gender- and ethnic differences (Sami vs. non-Sami), and the influence of pain related functional impairment. Methods: This is a cross-sectional study based on The Norwegian Arctic Adolescent Health Study; a school-based survey responded by 4,881 10th grade students (RR: 83%) in North Norway, in 2003-2005. 10% were indigenous Sami. Musculoskeletal pain was based on reported pain in the head, shoulder/neck, back and/or arm/knee/leg, measured by the number of pain sites. Linear multiple regression was used for the multivariable analyses. Results: The prevalence of musculoskeletal pain was high, and significantly higher in females. In total, 22.4% reported 3-4 pain sites. We found a strong association between musculoskeletal pain sites and psychosocial problems, with a higher explained variance in those reporting pain related functional impairment and in females. There were no major differences in the prevalence of musculoskeletal pain in Sami and non-Sami, however the associating factors differed somewhat between the indigenous and non-indigenous group. The final multivariable model, for the total sample, explained 21.2% of the variance of musculoskeletal pain. Anxiety/depression symptoms was the dominant factor associated with musculoskeletal pain followed by negative life events and school-related stress. Conclusions: Anxiety/depression, negative life events, and school-related stress were the most important factors associated with musculoskeletal pain, especially in those reporting pain related functional impairment. The most important sociocultural aspect is the finding that the indigenous Sami are not worse off. AN - WOS:000338968500003 AU - Eckhoff, C. AU - Kvernmo, S. C7 - 617 DA - Jun DO - 10.1186/1471-2458-14-617 N1 - Eckhoff, Christian Kvernmo, Siv Kvernmo, Siv/0000-0002-8406-2449; Eckhoff, Christian/0000-0003-1346-1386 1471-2458 PY - 2014 ST - Musculoskeletal pain in Arctic indigenous and non-indigenous adolescents, prevalence and associations with psychosocial factors: a population-based study T2 - Bmc Public Health TI - Musculoskeletal pain in Arctic indigenous and non-indigenous adolescents, prevalence and associations with psychosocial factors: a population-based study UR - ://WOS:000338968500003 VL - 14 ID - 2303 ER - TY - JOUR AB - Objectives: To examine the association between multisite musculoskeletal pain in adolescence and mental health disorders in young adulthood. Design and setting: Data were obtained from a linkage between the Norwegian Patient Registry (2008-2012) and the Norwegian Arctic Adolescent Health Study, a school-based survey conducted among 10th grade students in North Norway (2003-2005). Participants: In total, 3987 (68%) of all 5877 invited participants consented to the registry linkage. Outcome measures: Mental healthcare use and disorders from age 18-20 to 23-25 years (5 years). Methods: Musculoskeletal pain was measured by the number of musculoskeletal pain sites. Multivariable logistic regression was used to explore the association with later mental healthcare use and disorders. Results: Multisite adolescent musculoskeletal pain was significantly associated with an increase in mental healthcare use and mental health disorders in young adulthood. The relationship was stronger for anxiety and mood disorders, in both genders. Overall, the association between musculoskeletal pain and later mental health problems was attenuated after controlling for adolescent psychosocial and mental health problems, not by physical or sedentary activity. This could be due to confounding or mediation. However, when examining different mental health disorders, we found musculoskeletal pain to be significantly associated with anxiety disorders, and showing a strong trend in mood disorders, when adjusted for the adolescent factors. Conclusions: Physicians should be aware that multisite adolescent pain is associated with mental health problems in adolescence, and that these adolescents are at increased risk of mental health disorders in young adulthood. As youth troubled by mental health problems commonly present physical symptoms it is important to examine for psychosocial problems in order to offer early interventions. AN - WOS:000397872400014 AU - Eckhoff, C. AU - Straume, B. AU - Kvernmo, S. C7 - e012035 DA - Feb DO - 10.1136/bmjopen-2016-012035 IS - 2 N1 - Eckhoff, Christian Straume, Bjorn Kvernmo, Siv Kvernmo, Siv/0000-0002-8406-2449 PY - 2017 SN - 2044-6055 ST - Multisite musculoskeletal pain in adolescence and later mental health disorders: a population-based registry study of Norwegian youth: the NAAHS cohort study T2 - Bmj Open TI - Multisite musculoskeletal pain in adolescence and later mental health disorders: a population-based registry study of Norwegian youth: the NAAHS cohort study UR - ://WOS:000397872400014 VL - 7 ID - 2112 ER - TY - JOUR AB - Purpose: The purpose of this study was to describe and substantiate to experience of children, their families, and their caregivers with children's dental pain and to explore implications of these experiences for public policy. Methods: Data for 301 children presenting to 35 pediatric dentistry training programs during a 1-week period in 2000 for pain relief were collected with a questionnaire asking for: (1) sociodemographic characteristics; (2) oral health status; (3) dental care history; (4) presenting problem; (5) clinical findings; and (6) clinical disposition. Descriptive statistics are presented. Results: Among children presenting to training programs with oral pain, 28% were under age 6, 57% were on Medicaid, and 38% were regarded by their dentists to have "likely or obvious" functional impairment-with 22% reporting the highest pain level. Parents reported that 59% had "poor or fair oral health" and 29% had a prior dental emergency in the previous year. Pain, experienced for several days by 73% of children, was associated with difficulty: (1) eating; (2) sleeping; (3) attending school; and (4) playing. Parent-reported barriers to seeking dental care included: (1) missed work (24%); (2) transportation costs (12%); and (3) arranging child care (10%). Conclusion: In this study of children with dental pain, many suffered significant pain: (1) duration; (2) intensity; (3) recurrence; and (4) consequences. This study demonstrates the ongoing need for public policies that assure timely, comprehensive, and affordable dental care for vulnerable children. AN - WOS:000240710700008 AU - Edelstein, B. AU - Vargas, C. M. AU - Candelaria, D. AU - Vemuri, M. DA - Sep-Oct IS - 5 N1 - Edelstein, Burton Vargas, Clemencia M. Candelaria, Devanie Vemuri, Maryen Edelstein, Burton/AAO-8035-2020 Edelstein, Burton/0000-0001-6103-4827 1942-5473 PY - 2006 SN - 0164-1263 SP - 431-437 ST - Experience and policy implications of children presenting with dental emergencies to US pediatric dentistry training programs T2 - Pediatric Dentistry TI - Experience and policy implications of children presenting with dental emergencies to US pediatric dentistry training programs UR - ://WOS:000240710700008 VL - 28 ID - 2721 ER - TY - JOUR AB - Pain is undertreated in children due to historical reasons. The pain afferent tracts are developed in 21 weeks of gestation and it is well documented that preterm and neonates can experience pain. Pain in neonates leads to ncreased distress and altered pain response later in life. pain assessment in children is chalLenging. In the preverbal age using scales combining physiological and behavioral parameters help estimating the pain. Older children can use VAS scales but their pain scoring is affected by developmental age changes. Children respond to pain management treatments differently than adults. Some medications are not approved for use in children. Non-pharmacologic treatment is more effective, while invasive treatment such as regional nerve blocks for chronic pain is Less effective in children. Chronic pain is ignored or overlooked in children. This can lead to physicaL, emotional, psychological and social effects. Children may be absent from school and withdraw from their friends. Children with chronic pain will most likely become adults with chronic pain. Accepting chronic pain in children as a real problem and attempting to treat it at a young age may help decrease rates of adult pain in the future. The family doctor may be looking for serious causes for the pain. Referrals to specialists can Leave children without proper pain management or treatment. The Pediatric Pain Clinic is a multidisciplinary program specifically aiming to provide treatment and support for acute and chronic pain in children to conquer pain, help children to cope with chronic pain and avoid future complications. AD - Schneider Children's Medical Center of Israel. cmrachelef@clalit.org.il AN - 22991866 AU - Efrat, R. DA - Jun DP - NLM ET - 2012/09/21 IS - 6 KW - *Analgesics/administration & dosage/adverse effects Child Child Development Child Health Services/methods Chronic Pain Combined Modality Therapy Contraindications Early Medical Intervention Fetal Development Humans Infant, Newborn Infant, Premature *Pain/complications/diagnosis/physiopathology/psychology Pain Clinics/organization & administration Pain Management/*methods/psychology Pain Measurement/*methods Psychological Techniques *Stress, Psychological/etiology/physiopathology/therapy LA - heb N1 - Efrat, Rachel Journal Article Review Israel Harefuah. 2012 Jun;151(6):353-7, 377. PY - 2012 SN - 0017-7768 (Print) 0017-7768 SP - 353-7, 377 ST - [Pain in children in the 21st century] T2 - Harefuah TI - [Pain in children in the 21st century] VL - 151 ID - 3060 ER - TY - JOUR AB - Objective: To determine the prevalence of health and behaviour problems in a sample of children in homeless families and of psychological problems in their parents, and to assess the use of health services by homeless families. Design: A cross-sectional, questionnaire-based prevalence survey. Setting: Supported accommodation provided by a welfare service in Melbourne between May 1994 and June 1995. Subjects: 51 children from 31 families soon after housing crises. Results: More than one-third of all children had total behaviour problems scores in the ''deviant'' range (i.e., requiring mental health referral). Intellectual disability/developmental delay, skin problems, vision problems, recurrent headache, and asthma or other breathing problems were more prevalent in these homeless children than in a large Australian normative population. Their mothers scored higher than a large normative sample on the mental health questionnaire, most markedly for ''anxiety-insomnia'', ''severe depression'' and total score. Cost of treatment and transport difficulties were seen as barriers to using health care services. Recommendations: Australian health-care practitioners should be aware of the health and health service access problems of children in homeless families, and work to minimise their physical, emotional, developmental and academic disadvantages. Psychological support services should be available for homeless families, particularly for mothers. AN - WOS:A1996VY28800015 AU - Efron, D. AU - Sewell, J. R. AU - Horn, M. AU - Jewell, F. DA - Dec DO - 10.5694/j.1326-5377.1996.tb138670.x IS - 11-12 N1 - Efron, D Sewell, JR Horn, M Jewell, F PY - 1996 SN - 0025-729X SP - 630-633 ST - Children in homeless families in Melbourne: Health status and use of health services T2 - Medical Journal of Australia TI - Children in homeless families in Melbourne: Health status and use of health services UR - ://WOS:A1996VY28800015 VL - 165 ID - 2916 ER - TY - JOUR AB - Fourhundred and two (402) schoolchildren in the age-groups 7, 11 and 15 years answered a questionnaire concerning headache. Recurrent headache was reported by 23% of the children, while 52% said that they had headache occasionally. Headache was more common among the older children than among the younger ones, and in the oldest age-group headache was more common in girls than in boys. 6% of the children had consulted a physician for their headache. In most cases, the headache was of varying character. It often occurred in the afternoon and evening but even during schooltime, and was generally of short duration. Children with recurrent headache had more severe headache and headache of longer duration than children with headache occasionally who also more often thought that their headache was provoked by illness. In the oldest age-group a positive correlation was found between headache and a high rate of absence from school, and a negative correlation between headache and grade in physical education. AN - 7136609 AU - Egermark-Eriksson, I. DA - Jan DO - 10.1111/j.1651-2227.1982.tb09384.x DP - NLM ET - 1982/01/01 IS - 1 KW - Adolescent Age Factors Child Female Headache/*epidemiology/etiology Humans Male Mastication Migraine Disorders/epidemiology Recurrence School Health Services Sex Factors Surveys and Questionnaires Sweden Time Factors LA - eng N1 - Egermark-Eriksson, I Journal Article Research Support, Non-U.S. Gov't Sweden Acta Paediatr Scand. 1982 Jan;71(1):135-40. doi: 10.1111/j.1651-2227.1982.tb09384.x. PY - 1982 SN - 0001-656X (Print) 0001-656x SP - 135-40 ST - Prevalence of headache in Swedish schoolchildren. A questionnaire survey T2 - Acta Paediatr Scand TI - Prevalence of headache in Swedish schoolchildren. A questionnaire survey VL - 71 ID - 3419 ER - TY - JOUR AB - Neck pain (NP) is a common occupational health problem associated with a number of professions. Many studies indicate that NP is common among teachers, yet no published study was found to address the prevalence and risk factors of NP in Iranian school teachers. The purpose of the current study was to assess the prevalence and risk factors for NP among school teachers in Iran. A cross-sectional study was conducted on 586 randomly selected primary and high schools teachers from 22 schools in Tehran, Iran. Point, last month, last 6 months, annual, and lifetime prevalence rates of NP were 24%, 29%, 33%, 37%, and 43%, respectively. There was a significant association and increased prevalence of NP with a number of risk factors such as; being female, age, general health, length of employment, regular exercise and job satisfaction (P < 0.05 in all instances). Therefore, some individual and occupational factors may make conditions relevant for the development of NP among teachers. AD - Neuromuscular Rehabilitation Research Center, Semnan University of Medical Sciences, Semnan, Iran. Electronic address: fatemehehsani59@yahoo.com. Pediatric Neurorehabilitation Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran; University Institute of Physical Therapy, Faculty of Allied Health Sciences, University of Lahore, Lahore, Pakistan. Electronic address: Mohseni_Bandpei@Yahoo.com. Department of Physical Therapy, Occupational Therapy, Rehabilitation and Physical Medicine, Universidad Rey Juan Carlos, Alcorcón, Madrid, Spain. Electronic address: Cesar.fernandez@ujrc.es. Department of Physiotherapy, Babol University of Medical Sciences, Babol, Iran. Electronic address: Kjavanshir@yahoo.com. AN - 29332759 AU - Ehsani, F. AU - Mohseni-Bandpei, M. A. AU - Fernández-De-Las-Peñas, C. AU - Javanshir, K. DA - Jan DO - 10.1016/j.jbmt.2017.04.003 DP - NLM ET - 2018/01/16 IS - 1 KW - Adult Age Factors Body Weight Cross-Sectional Studies Exercise Female Health Status Humans Iran/epidemiology Job Satisfaction Male Middle Aged Neck Pain/*epidemiology/therapy Occupational Diseases/*epidemiology/therapy Occupational Health Pain Management/methods Prevalence Risk Factors School Teachers/*statistics & numerical data Sex Factors *Neck pain *Prevalence *Risk factor *School teachers LA - eng N1 - 1532-9283 Ehsani, Fatemeh Mohseni-Bandpei, Mohammad Ali Fernández-De-Las-Peñas, César Javanshir, Khodabakhsh Journal Article United States J Bodyw Mov Ther. 2018 Jan;22(1):64-68. doi: 10.1016/j.jbmt.2017.04.003. Epub 2017 Apr 5. PY - 2018 SN - 1360-8592 SP - 64-68 ST - Neck pain in Iranian school teachers: Prevalence and risk factors T2 - J Bodyw Mov Ther TI - Neck pain in Iranian school teachers: Prevalence and risk factors VL - 22 ID - 3840 ER - TY - JOUR AB - We conducted a prospective trial at a military medical center to determine which treatment for first-time ankle sprains, early mobilization or immobilization, is more effective. Eighty-two patients with a lateral ankle sprain were randomly selected for one of two treatment groups. The Early Mobilization Group received an elastic wrap for 2 days followed by functional bracing for 8 days. Two days after injury, this group began weight-bearing and an ankle rehabilitation program. Patients in the Immobilization Group were placed in a nonweight-bearing plaster splint for 10 days followed by weight-bearing and the same rehabilitation program. Patients in the Early Mobilization Group had less pain at 3 weeks (57% versus 87%, P = 0.02); otherwise, there were no significant differences between groups in the frequency of residual symptoms. Only one patient in each group had residual symptoms 1 year after injury. Three patients (8%) in each group resprained their ankles. Ten days after injury, patients in the Early Mobilization Group were more likely to be back to full work (54% versus 13%, P < 0.001). We conclude that in first-time lateral ankle sprains, although both immobilization and early mobilization prevent late residual symptoms and ankle instability, early mobilization allows earlier return to work and may be more comfortable for patients. AD - Department of Family Medicine, Oregon Health Sciences University, Portland 97201-3098. AN - 8129116 AU - Eiff, M. P. AU - Smith, A. T. AU - Smith, G. E. DA - Jan-Feb DO - 10.1177/036354659402200115 DP - NLM ET - 1994/01/01 IS - 1 KW - Absenteeism Adolescent Adult Ankle Injuries/diagnosis/diagnostic imaging/physiopathology/rehabilitation/*therapy Bandages Braces Crutches *Early Ambulation Exercise Therapy Follow-Up Studies Humans *Immobilization Middle Aged Pain/physiopathology Prospective Studies Radiography Range of Motion, Articular/physiology Recurrence Splints Sprains and Strains/diagnosis/diagnostic imaging/physiopathology/rehabilitation/*therapy Weight-Bearing/physiology LA - eng N1 - Eiff, M P Smith, A T Smith, G E Clinical Trial Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't United States Am J Sports Med. 1994 Jan-Feb;22(1):83-8. doi: 10.1177/036354659402200115. PY - 1994 SN - 0363-5465 (Print) 0363-5465 SP - 83-8 ST - Early mobilization versus immobilization in the treatment of lateral ankle sprains T2 - Am J Sports Med TI - Early mobilization versus immobilization in the treatment of lateral ankle sprains VL - 22 ID - 3486 ER - TY - JOUR AB - OBJECTIVE: Controversy exists regarding which febrile children with sickle cell disease (SCD) should receive a chest x-ray (CXR). Our goal is to provide data informing the decision of which febrile children with SCD presenting to the emergency department (ED) require a CXR to evaluate for acute chest syndrome (ACS). METHODS: Retrospective chart review of children ages 3 months to 21 years with SCD presenting to the ED at one of two academic children's hospitals with fever ≥38.5°C between January 1, 2010, and December 31, 2012. Demographic characteristics, respiratory symptoms, and laboratory results were abstracted. The primary outcome was the presence of ACS. Binary recursive partitioning was performed to determine predictive factors for a diagnosis of ACS. RESULTS: A total of 185 (10%) of 1,837 febrile ED visits met ACS criteria. The current National Heart, Lung, and Blood Institute (NHLBI) consensus criteria for obtaining a CXR (shortness of breath, tachypnea, cough, or rales) identified 158 (85%) of ACS cases, while avoiding 825 CXRs. Obtaining a CXR in children with NHLBI criteria or chest pain and in children without those symptoms but with a white blood cell (WBC) count ≥18.75 × 10(9) /L or a history of ACS identified 181 (98%), while avoiding 430 CXRs. CONCLUSION: Children with SCD presenting to the ED with fever and shortness of breath, tachypnea, cough, rales, or chest pain should receive a CXR due to high ACS rates. A higher WBC count or history of ACS in a child without one of those symptoms may suggest the need for a CXR. Prospective validation of these criteria is needed. AD - Medical College of Wisconsin, Milwaukee, WI. Pediatric Emergency Medicine and the Children's Research Institute, Medical College of Wisconsin, Milwaukee, WI. Pediatrics, Pediatric Emergency Medicine, Children's Hospital of Philadelphia, Philadelphia, PA. Children's Research Institute, Children's Hospital of Wisconsin, and Quantitative Health Sciences, Medical College of Wisconsin, Milwaukee, WI. AN - 27404765 AU - Eisenbrown, K. AU - Nimmer, M. AU - Ellison, A. M. AU - Simpson, P. AU - Brousseau, D. C. DA - Nov DO - 10.1111/acem.13048 DP - NLM ET - 2016/11/02 IS - 11 KW - Acute Chest Syndrome/*diagnostic imaging/*etiology Anemia, Sickle Cell/*complications Child Child, Preschool Emergency Service, Hospital Female Fever/*etiology Hospitals, Pediatric Humans Infant Leukocyte Count Male Prospective Studies Radiography, Thoracic/*statistics & numerical data Retrospective Studies Sensitivity and Specificity LA - eng N1 - 1553-2712 Eisenbrown, Katherine Nimmer, Mark Ellison, Angela M Simpson, Pippa Brousseau, David C R01 NS030678/NS/NINDS NIH HHS/United States Case Reports Journal Article Multicenter Study United States Acad Emerg Med. 2016 Nov;23(11):1248-1256. doi: 10.1111/acem.13048. Epub 2016 Nov 1. PY - 2016 SN - 1069-6563 SP - 1248-1256 ST - Which Febrile Children With Sickle Cell Disease Need a Chest X-Ray? T2 - Acad Emerg Med TI - Which Febrile Children With Sickle Cell Disease Need a Chest X-Ray? VL - 23 ID - 4004 ER - TY - JOUR AB - We compared the efficacy and tolerability of oral piroxicam 1 mg/kg/day with soluble aspirin given at 100 mg/kg/day taken four-hourly in 58 patients with sickle cell anaemia and severe ostcoarticular painful attacks requiring hospitalization in a randomized, paralleled study. Main investigational criteria were pain relief, limitation of movement, fever, and insomnia or agitation. Both groups were well-matched at the commencement of therapy but most patients on piroxicam showed remarkable and significant pain relief and improvement in other parameters within 24 h. Unwanted effects were absent in the piroxicam-treated group whereas those treated with aspirin experienced nausea and vomiting. There were no significant changes in liver function tests with both forms of treatment. Oral piroxicam is an effective and safe treatment in the management of the osteoarticular painful crisis in sickle cell anaemia. It might prevent the use of parenteral analgesics and hospitalization and reduce the loss of school hours in patients who are being treated for bone pain crises that characterize sickle cell anaemia. AD - Department of Paediatrics, University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria. eke.obowu@alpha.linkserve.com AN - 10747265 AU - Eke, F. U. AU - Obamyonyi, A. AU - Eke, N. N. AU - Oyewo, E. A. DA - Feb DO - 10.1046/j.1365-3156.2000.00507.x DP - NLM ET - 2000/04/04 IS - 2 KW - Adolescent Anemia, Sickle Cell/*physiopathology Anti-Inflammatory Agents, Non-Steroidal/administration & dosage/adverse effects/*therapeutic use Arthralgia/*drug therapy Aspirin/administration & dosage/therapeutic use *Bone and Bones Child Child, Preschool Female Humans Male Pain/*drug therapy/etiology Piroxicam/administration & dosage/adverse effects/*therapeutic use LA - eng N1 - Eke, F U Obamyonyi, A Eke, N N Oyewo, E A Clinical Trial Comparative Study Journal Article Randomized Controlled Trial England Trop Med Int Health. 2000 Feb;5(2):81-4. doi: 10.1046/j.1365-3156.2000.00507.x. PY - 2000 SN - 1360-2276 (Print) 1360-2276 SP - 81-4 ST - An open comparative study of dispersible piroxicam versus soluble acetylsalicylic acid for the treatment of osteoarticular painful attack during sickle cell crisis T2 - Trop Med Int Health TI - An open comparative study of dispersible piroxicam versus soluble acetylsalicylic acid for the treatment of osteoarticular painful attack during sickle cell crisis VL - 5 ID - 3943 ER - TY - JOUR AB - PURPOSE: To describe parent perceptions of their child's quality of life (QOL) and their satisfaction with health care for a group of children with medical complexity (CMC), and to determine whether parent perceptions of child well-being are associated with QOL and health care satisfaction. METHODS: Participants were parents or legal guardians of children enrolled in a novel program of intensive outpatient care for CMC. Participants completed 7-item questionnaires to ascertain their perceptions of their child's well-being, QOL and health care satisfaction. RESULTS: One hundred and ninety-one participants completed questionnaires (response rate 100%). 85% rated their child's QOL as excellent, very good, or good. 87% reported satisfaction with their child's health care. Fair or poor mental health was associated with fair or poor QOL (OR 1.09, p = 0.0002). More pain was associated with lower QOL (OR 1.07, p = 0.0022). Fewer days of play or school attendance were associated with lower satisfaction with health care (OR 1.09, p = 0.0003). CONCLUSION: Our study suggests that more pain and worse mental health are associated with parental perceptions of the quality of life for their CMC. Clinicians who care for these children and their families should carefully and repeatedly assess for these important symptoms. AN - WOS:000448286400004 AU - Ellzey, A. AU - Valentine, K. J. AU - Hagedorn, C. AU - Murphy, N. A. DO - 10.3233/prm-150323 IS - 2 N1 - Ellzey, Allison Valentine, Karen J. Hagedorn, Caroline Murphy, Nancy A. 1875-8894 PY - 2015 SN - 1874-5393 SP - 97-104 ST - Parent perceptions of quality of life and healthcare satisfaction for children with medical complexity T2 - Journal of Pediatric Rehabilitation Medicine TI - Parent perceptions of quality of life and healthcare satisfaction for children with medical complexity UR - ://WOS:000448286400004 VL - 8 ID - 2266 ER - TY - JOUR AB - Objectives: Inflammatory bowel diseases (IBDs) are chronic diseases which negatively affect the schooling of children. The aim is to analyze school absenteeism and its causes in children followed for IBD. Methods: A prospective multicenter study of IBD patients aged from 5 to 18 years old, from September 2016 to June 2017. Data on absenteeism and its causes were collected via a monthly questionnaire completed by patients or their family by mail. The results were compared with existing data supplied by the school authorities (497 students without IBD divided by class). Results: A total of 106 patients (62 boys), median age of 14 (5-18), were included. The global response rate was 83.1%. The patients with IBD were absent an average of 4.8% +/- 5.5% of school days during the school year, against 3.2% +/- 1.6% for non IBD group (P = 0.034). Digestive disorders accounted for 34% of the causes of absenteeism. Approximately 27% of the absences were due to scheduled events (hospitalizations, endoscopy, or consultations). By excluding the absences for scheduled care, the rate of school absenteeism of patients with IBD is significantly lower than that of non-IBD group. Conclusion: Children with IBD are more frequently absent from school than non-IBD group. The main cause of school absenteeism appears to be associated with the disease itself. The share of scheduled absenteeism is quite large. The organization and scheduling of the patients' care path must be a priority to maximally limit the negative impact of their disease on the patients' schooling. AN - WOS:000480690100021 AU - Eloi, C. AU - Foulon, G. AU - Bridoux-Henno, L. AU - Breton, E. AU - Pelatan, C. AU - Chaillou, E. AU - Grimal, I. AU - Darviot, E. AU - Carre, E. AU - Gastineau, S. AU - Tourtelier, Y. AU - Nicaise, D. AU - Rousseau, C. AU - Dabadie, A. DA - Apr DO - 10.1097/mpg.0000000000002207 IS - 4 N1 - Eloi, Clementine Foulon, Gauthier Bridoux-Henno, Laure Breton, Estelle Pelatan, Cecile Chaillou, Emilie Grimal, Isabelle Darviot, Estelle Carre, Emilie Gastineau, Swellen Tourtelier, Yann Nicaise, Dorothee Rousseau, Chloe Dabadie, Alain 1536-4801 PY - 2019 SN - 0277-2116 SP - 541-546 ST - Inflammatory Bowel Diseases and School Absenteeism T2 - Journal of Pediatric Gastroenterology and Nutrition TI - Inflammatory Bowel Diseases and School Absenteeism UR - ://WOS:000480690100021 VL - 68 ID - 1932 ER - TY - JOUR AB - Migraine is a common clinical diagnosis, occurring in 4-10% of school age children. Migraine in the infant and preschool child has been infrequently described in retrospective studies. We report the prospective evaluation and therapy of six children (5-42 months) with migraine. In four of the children, Prensky's criteria were used for diagnosis, while the two youngest children presented with ophthalmoplegic migraine. All children had a strong family history of migraine and presented with headache and prominent features including facial pallor, irritability, sleep disturbance or mood changes. The oldest four children were successfully treated with either amitriptyline or imipramine in low doses. The infants with ophthalmoplegic migraine failed to completely respond to any therapy. At followup 2 to 18 months later, all children were well and without toxicity. The pediatrician should be aware that migraine may begin in infancy and can be effectively and safely treated. AD - Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock. AN - 2370139 AU - Elser, J. M. AU - Woody, R. C. DA - May DO - 10.1111/j.1526-4610.1990.hed3006366.x DP - NLM ET - 1990/05/01 IS - 6 KW - Amitriptyline/therapeutic use Child, Preschool Female Humans Imipramine/therapeutic use Infant Male *Migraine Disorders/complications/drug therapy Ophthalmoplegia/etiology Prospective Studies LA - eng N1 - Elser, J M Woody, R C Case Reports Journal Article United States Headache. 1990 May;30(6):366-8. doi: 10.1111/j.1526-4610.1990.hed3006366.x. PY - 1990 SN - 0017-8748 (Print) 0017-8748 SP - 366-8 ST - Migraine headache in the infant and young child T2 - Headache TI - Migraine headache in the infant and young child VL - 30 ID - 3662 ER - TY - JOUR AB - PURPOSE Raising awareness of colorectal cancer (CRC) symptoms for early recognition, reduction of modifiable risk factors, and removing barriers to seeking medical help could lower its mortality. This study aimed to assess the level of public awareness of CRC in the Gaza Strip. MATERIALS AND METHODS This was a cross-sectional study conducted at three hospitals and 10 high schools between September and October 2017. The Arabic version of the validated Bowel Cancer Awareness Measure (BoCAM) questionnaire was used to evaluate awareness of CRC symptoms and risk factors, and barriers to seeking medical help. Adults (age >= 18 years) in three major hospitals and adolescents (ages 15 to 17 years) in 10 schools were recruited for face-to-face interviews to complete the BoCAM. RESULTS Of 3,172 potential participants, 3,080 completed the BoCAM (response rate, 97.1%). Among these, 1,578 (51.2%) were adults and 1,614 (52.4%) were females. Persistent abdominal pain was the most commonly recognized CRC symptom (n = 1,899; 61.7%), whereas anorectal pain was the least common (n = 1,056; 34.3%). In total, 2,177 (70.7%) were not confident in recognizing CRC symptoms or signs. Having a bowel disease was the most frequently recognized CRC risk factor (n = 1,456; 47.3%) and diabetes the least recognized (n = 591; 19.2%). The overall mean scores +/- standard deviations for recalling and recognizing CRC symptoms were 1.2 +/- 1.3 and 4.3 +/- 2.3, respectively (out of 9 points). The overall mean scores +/- standard deviations for recalling and recognizing CRC risk factors were 0.7 +/- 0.8 and 8.0 +/- 3.1, respectively (out of 16 points). Emotional barriers were the most commonly reported barriers to seeking medical help, with feeling worried about what a doctor might find as the most common barrier (n = 1,522; 49.4%). CONCLUSION Public awareness of CRC is suboptimal in Gaza. Improving CRC awareness with educational interventions is needed, including in local schools. (C) 2019 by American Society of Clinical Oncology AN - WOS:000470165300001 AU - Elshami, M. AU - Alfaqawi, M. AU - Abdalghafoor, T. AU - Nemer, A. A. AU - Ghuneim, M. AU - Lubbad, H. AU - Almahallawi, B. AU - Samaan, M. AU - Alwali, A. AU - Alborno, A. AU - Al-kafarna, D. AU - Salah, A. AU - Shihada, K. AU - Amona, M. A. AU - Al-Najjar, A. AU - Abu Subha, R. AU - Alhelu, B. AU - Abujayyab, I. AU - Albarqouni, L. AU - Bottcher, B. DA - May DO - 10.1200/jgo.18.00252 N1 - Elshami, Mohamedraed Alfaqawi, Maha Abdalghafoor, Tamer Nemer, Ayoob A. Ghuneim, Mohammed Lubbad, Hussien Almahallawi, Batool Samaan, Mosab Alwali, Abdallah Alborno, Ahmad Al-kafarna, Deyaa Salah, Aseel Shihada, Karam Amona, Mohammed Abo Al-Najjar, Amira Abu Subha, Rana Alhelu, Basma Abujayyab, Israa Albarqouni, Loai Bottcher, Bettina Bottcher, Bettina/AAN-1708-2020 Elshami, Mohamedraed/0000-0002-9977-0923; Albarqouni, Loai/0000-0002-4114-9106 PY - 2019 SN - 2378-9506 ST - Public Awareness and Barriers to Seeking Medical Advice for Colorectal Cancer in the Gaza Strip: A Cross-Sectional Study T2 - Journal of Global Oncology TI - Public Awareness and Barriers to Seeking Medical Advice for Colorectal Cancer in the Gaza Strip: A Cross-Sectional Study UR - ://WOS:000470165300001 VL - 5 ID - 1922 ER - TY - JOUR AB - OBJECTIVE: To discuss the use of an upper cervical technique in the case of a 23-year-old male patient with rapid-cycling bipolar disorder, sleep disorder, seizure disorder, neck and back pain, and migraine headaches. CLINICAL FEATURES: The patient participated in a high school track meet at age 17, landing on his head from a height of 10 ft while attempting a pole vault. Prior to the accident, no health problems were reported. Following the accident, the patient developed numerous neurological disorders. Symptoms persisted over the next 6 years, during which time the patient sought treatment from many physicians and other health care practitioners. INTERVENTION AND OUTCOME: At initial examination, evidence of a subluxation stemming from the upper cervical spine was found through thermography and radiography. Chiropractic care using an upper cervical technique was administered to correct and stabilize the patient's upper neck injury. Assessments at baseline, 2 months, and 4 months were conducted by the patient's neurologist. After 1 month of care, the patient reported an absence of seizures and manic episodes and improved sleep patterns. After 4 months of care, seizures and manic episodes remained absent and migraine headaches were reduced from 3 per week to 2 per month. After 7 months of care, the patient reported the complete absence of symptoms. Eighteen months later, the patient remains asymptomatic. CONCLUSION: The onset of the symptoms following the patient's accident, the immediate reduction in symptoms correlating with the initiation of care, and the complete absence of all symptoms within 7 months of care suggest a link between the patient's headfirst fall, the upper cervical subluxation, and his neurological conditions. Further investigation into upper cervical trauma as a contributing factor to bipolar disorder, sleep disorder, seizure disorder, and migraine headaches should be pursued. AD - erin@erinelster.com AN - 15129207 AU - Elster, E. L. DA - Mar-Apr DO - 10.1016/j.jmpt.2003.12.027 DP - NLM ET - 2004/05/07 IS - 3 KW - Adolescent Adult Athletic Injuries/complications Bipolar Disorder/etiology/*therapy Cervical Atlas/injuries Cervical Vertebrae/*injuries Humans Male *Manipulation, Chiropractic/methods Migraine Disorders/etiology/*therapy Neck Injuries/*complications/diagnostic imaging/*therapy Neck Pain/etiology/therapy Radiography Seizures/etiology/*therapy Sleep Wake Disorders/etiology/*therapy Sprains and Strains/etiology/therapy Thermography Time Factors Treatment Outcome LA - eng N1 - Elster, Erin L Case Reports Journal Article United States J Manipulative Physiol Ther. 2004 Mar-Apr;27(3):E5. doi: 10.1016/j.jmpt.2003.12.027. PY - 2004 SN - 0161-4754 (Print) 0161-4754 SP - E5 ST - Treatment of bipolar, seizure, and sleep disorders and migraine headaches utilizing a chiropractic technique T2 - J Manipulative Physiol Ther TI - Treatment of bipolar, seizure, and sleep disorders and migraine headaches utilizing a chiropractic technique VL - 27 ID - 3746 ER - TY - JOUR AB - Spondylolysis and spondylolisthesis occur predominantly in the lower lumbar spine. Besides congenital defects such as predisposition of spondylolysis the correlation between competitive sports activities and an increased incidence of spondylolysis is proved. In early stages, complete healing can be achieved by conservative treatment (abstinence from sports activities for 3 months, orthesis). Persistence of pain, neurologic symptoms and progression of vertebral slipping are indications for operative treatment (reconstruction of the isthmus, dorso-ventral spondylodesis). The exercise tolerance depends on the extent of instability, progression of vertebral slipping and clinical symptoms. The limits of exercise tolerance vary among the individual athletes and require the decision of the physician. Backstroke swimming, abdominal and back muscle strengthening exercises, and types of sport involving smooth movements are advisable. Sports education in school is possible without restriction in patients with stable spondylolysis and in those with spondylolisthesis without unfavourable concomitant factors. AN - WOS:A1997YA99900003 AU - Engelhardt, M. AU - Reuter, J. AU - Freiwald, J. AU - Bohme, T. AU - Halbsguth, A. DA - Sep DO - 10.1007/pl00003437 IS - 9 N1 - Engelhardt, M Reuter, J Freiwald, J Bohme, T Halbsguth, A 1433-0431 PY - 1997 SN - 0085-4530 SP - 755-759 ST - Spondylolysis and spondylolisthesis: correlation with sport T2 - Orthopade TI - Spondylolysis and spondylolisthesis: correlation with sport UR - ://WOS:A1997YA99900003 VL - 26 ID - 2905 ER - TY - JOUR AB - Address correspondence to: Dr. Carla S. Enriquez, Physical Therapy Program, Stockton University School of Health Sciences, 101 Vera King Farris Drive, Galloway, NJ 08205-9441, USA. Tel 609-626-3508, fax 609-652-4858. carla.enriquez@stockton.edu. PURPOSE: To investigate the association between pain sensitivity and endogenous supraspinal pain modulation activity using quantitative sensory tests (QST) in patients with orofacial pain. METHODS: Temporal summation (TS) testing and conditioned pain modulation (CPM) are QSTs used to quantify individual pain processing mechanisms. TS testing was used to assess pain sensitivity which correlates to central sensitization and CPM for endogenous pain modulation. These tests were administered to a convenience sample of patients with orofacial pain (n=40) seen for initial examination in an orofacial pain clinic. Bivariate correlation analyses were conducted on TS and CPM scores, including age and gender. RESULTS: A strong linear correlation was found between pain sensitivity and endogenous pain modulation (r=0.69, p<0.001). QST outcomes suggest that inefficient endogenous pain modulation is positively correlated with the magnitude of pain sensitivity among individuals who seek treatment for orofacial pain. A weak linear correlation was also found between TS and age (r=0.37, p=0.02). CONCLUSION: QSTs demonstrated a strong association between heightened pain sensitivity and inefficient endogenous pain modulation revealed from higher pain report on TS and CPM testing in patients with orofacial pain. Our findings provide supporting evidence on the impairments in pain-processing mechanisms that require consideration when evaluating orofacial pain etiology, where increased pain sensitivity and aberrant pain modulation appear to significantly contribute in prolonged and persistent pain experience. AD - Physical Therapy Program, Stockton University School of Health Sciences, 101 Vera King Farris Drive, Galloway, NJ 08205-9441, USA. Tel 609-626-3508, fax 609-652-4858. carla.enriquez@stockton.edu. AN - 31167010 AU - Enriquez, C. S. DA - Summer DP - NLM ET - 2019/06/06 IS - 2 KW - Adolescent Adult Aged Aged, 80 and over Facial Pain/*physiopathology Female Humans Male Middle Aged Pain Measurement/*methods Pain Threshold Postsynaptic Potential Summation/*physiology Young Adult LA - eng N1 - 1945-404x Enriquez, Carla S Journal Article United States J Allied Health. 2019 Summer;48(2):95-99. PY - 2019 SN - 0090-7421 SP - 95-99 ST - Association Between Pain Sensitivity and Endogenous Supraspinal Pain Modulation in Patients with Orofacial Pain T2 - J Allied Health TI - Association Between Pain Sensitivity and Endogenous Supraspinal Pain Modulation in Patients with Orofacial Pain VL - 48 ID - 4058 ER - TY - JOUR AB - Data from a community-based four-year prospective study were used to investigate the relationship between marital disruption and long-term work disability. In 1990, all inhabitants of the municipality Ullensaker, Norway, belonging to six cohorts (20 - 22 years, 30 - 32 years, 40 - 42 years, 50 - 52 years, 60 - 62 years and 70 - 72 years) were sent a questionnaire. Of the 1,359 respondents who were working, married or cohabiting, and not older than 62 years, 1,115 (82%) returned a second questionnaire four years later (1994). Separation or divorce between 1990 and 1994 was related to long-term work disability in 1994 (OR = 3.02; 95% CI: 1.57 - 5.81), even after adjustments for age, sex, work characteristics, number of work hours per week, job satisfaction, body mass index, having pre-school children, smoking, physical leisure activity, emotional symptoms and musculoskeletal pain (all measured in 1990). Emotional problems evoked by the marital disruption may be part of the explanation. AN - WOS:000082264000006 AU - Eriksen, W. AU - Natvig, B. AU - Bruusgaard, D. DA - Sep DO - 10.1177/14034948990270031101 IS - 3 N1 - Eriksen, W Natvig, B Bruusgaard, D PY - 1999 SN - 1403-4948 SP - 196-202 ST - Marital disruption and long-term work disability - A four-year prospective study T2 - Scandinavian Journal of Public Health TI - Marital disruption and long-term work disability - A four-year prospective study UR - ://WOS:000082264000006 VL - 27 ID - 2878 ER - TY - JOUR AB - Background: Transitional object (TO) use is suggested to be related with various health problems. Prolonged TO use in adolescence is quite common, and research on its associations with health and psychosocial wellbeing is relevant because it does not necessarily represent pathologies in this age group.Aims: To investigate the role of transitional phenomena and attachment to an inanimate object in adolescence, possible explanatory variables were studied, including sociodemographic and psychosocial factors and self-image.Methods: The study group consisted of 992 subjects (433 boys and 559 girls), mean age 14.5 years (SD=0.5), who were studying at comprehensive schools in the City of Turku, Finland. Information about the TO use and background data were collected with a semi-structured questionnaire. Mental distress and self-esteem were assessed by the Offer Self-Image Questionnaire (OSIQ).Results: The multivariable logistic regression analysis revealed that, in the whole study group, significant explanatory factors for the TO use included female gender (p<0.0001), frequent pain and aches (p=0.008), and, of the OSIQ sub-scales, low Emotional Health (p=0.006). For girls, significant explanatory factors for the TO use were pain and aches (p=0.003) and low Emotional Health (p=0.002). For boys, the only statistically significant explanatory factor was pain and aches (p=0.02).Conclusions: The TO may serve as a soothing element for somatoform pain symptoms in adolescence. Identifying of the TO use may help one see an adolescent's possible distress, symptoms of pains, and problems in psychological resilience. AN - WOS:000383037300009 AU - Erkolahti, R. AU - Nystrom, M. AU - Vahlberg, T. AU - Ebeling, H. DA - Oct DO - 10.1080/08039488.2016.1179339 IS - 7 N1 - Erkolahti, Ritva Nystrom, Marjaana Vahlberg, Tero Ebeling, Hanna 1502-4725 PY - 2016 SN - 0803-9488 SP - 536-541 ST - Transitional object use in adolescence: a developmental phenomenon or a sign of problems? T2 - Nordic Journal of Psychiatry TI - Transitional object use in adolescence: a developmental phenomenon or a sign of problems? UR - ://WOS:000383037300009 VL - 70 ID - 2143 ER - TY - JOUR AB - There is a lack of data on parental attitudes toward children with primary headaches. The aim of this study is to determine whether there is a relationship between primary headaches and parental attitudes in the pre-adolescent pediatric population. In this cross-sectional study, 195 children with primary headache and 43 healthy children aged 9-16 years were included. A questionnaire for sociodemographic variables, visual analog scale (VAS), Social Anxiety Scale and Depression Inventory for Adolescents and Children, and Parental Attitudes Determining Scale (PATS), which is an attitude measure specifically designed to evaluate psychological adjustment, were administered. Of 195 children (female/male ratio: 89/106, mean age: 12.59 +/- 1.09 years), episodic migraine (n = 90), chronic migraine (n = 25), and tension-type headache (n = 80) were evaluated. There was no significant difference among headache groups and healthy subjects in terms of depression, anxiety, and fathers' attitude scale scores. However, there were significant differences in mean mothers' attitude scale scores and VAS scores (p = .002, p = .000). Mean oppressive-authoritarian attitude subscale scores of mothers' was significantly higher in children with chronic migraine (p = .000). A relationship between depression and VAS scores among all patient groups was detected (p = .000). Parental age was negatively related to PATS scores of children with episodic migraine and tension-type headache (p = .037 and p = .036). Parental attitudes may elevate psychiatric symptoms and influence children's perception of pain intensity and result in chronification of headache. Our findings support that mothers' attitude toward children with chronic migraine has strong impacts on the child's pain experience. AN - WOS:000485959900010 AU - Ertem, D. H. AU - Bingol, A. AU - Ugurcan, B. AU - Mercan, O. AU - Simsek, I. AU - Saglam, H. AU - Ozge, A. AU - Uluduz, D. DA - Oct DO - 10.1177/1359104519838571 IS - 4 N1 - Ertem, Devrimsel Harika Bingol, Ayhan Ugurcan, Busra Mercan, Ozlem Simsek, Ismail Saglam, Hanife Ozge, Aynur Uluduz, Derya Mercan, Ozlem/AAA-3052-2020 ertem, harika/0000-0001-5309-1258; Simsek, Ismail/0000-0002-5087-5863; Saglam, Hanife/0000-0003-3256-1227 1461-7021 PY - 2019 SN - 1359-1045 SP - 767-775 ST - The impact of parental attitudes toward children with primary headaches T2 - Clinical Child Psychology and Psychiatry TI - The impact of parental attitudes toward children with primary headaches UR - ://WOS:000485959900010 VL - 24 ID - 1882 ER - TY - JOUR AB - The paper represents a modern view on the problem of tension-type headache (TTH) in adolescents, which is caused by the following factors: information overload and other types of stress, sleep deprivation, and physical activity deficiency, impaired posture with myogenic trigger points developing. The research covered 64 adolescents aged 14-15 with tension-type headaches: 33 boys and 42 girls (11 boys and 20 girls with frequent episodic tension-type headache (ETTH) and 12 boys and 21 girls with chronic tension-type headache (CTTH)). We assessed accompanying symptoms over the last 6 months according to the Likert scale. All children were prescribed GABA receptor agonist-aminophenylbutyric acid hydrochloride 250 mg three times a day for 3 weeks. The reduction of tension-type headache intensity was assessed by 3-grade scale: Bno change,' "significantly reduced," and "completely stopped": 0-no, 1-very seldom, 2-often, and 3-permanently. ETTH/CTTH associated symptoms are as follows: (1) difficulty of falling asleep and restless sleep (0.91 +/- 0.83/1.54 + 1.26), (2) difficulty of concentrating during the day (0.61 + 0.92/2.04 + 1.21), (3) morning sickness (0.32 + 0.87/1.81 + 1.29), (4) feeling ill in the morning with improvement in the second half of the day (0.17 + 0.57/1 95 + 0.95), (5) meteosensitivity (0.58 + 1.01/1.59 + 1.22), and (6) decrease in physical capability (0.20 + 0.64/1.72 + 0.82). After 3 weeks, the pain in ETTH subgroup completely stopped in 27 children (79%) and significantly reduced in 7 (21%). In CTTH subgroup, the pain completely stopped in 9 children (41%) and significantly reduced in 13 (59%). Associated symptoms of ETTH/CTTH are as follows: (1) difficulty of falling asleep and restless sleep (0.26 + 0.44, p = 0.000093/0.45 + 0.80, p = 0.000224), (2) difficulty of concentrating during the day (0.17 + 0.38, p = 0.003707/0.54 + 0.85; p = 0.000007), (3) morning sickness (0.08 + 0.28, p = 0. 058101/0.77 + 1.06, p = 0.001682), (4) feeling ill in the morning with improvement in the second half of the day (0.08 + 0.28, p = 0.083119/0.27 + 0.45; p = 0.000000), (5) meteosensitivity (0.32 + 0.63, p = 0.010304/1.36 + 1.09, p = 0.021450), and (6) decrease in physical capability (0.058 + 0 23; p = 0.133706 /0.95 + 1.04, p = 0.005055). Aminophenylbutyric acid hydrochloride (GABA receptor agonist) reduces the intensity of tension-type headache and has a positive effect on associated symptoms. It can be recommended for inclusion into the scheme of tension-type headache treatment in schoolchildren. AN - WOS:000429407500048 AU - Esin, O. R. DA - Mar DO - 10.1007/s12668-018-0507-6 IS - 1 N1 - Esin, Oleg Radievich Esin, Oleg/D-7483-2015 2191-1649 PY - 2018 SN - 2191-1630 SP - 418-422 ST - Treatment of Tension-Type Headaches in Adolescents (14-15 Years Old): the Efficacy of Aminophenylbutyric Acid Hydrochloride T2 - Bionanoscience TI - Treatment of Tension-Type Headaches in Adolescents (14-15 Years Old): the Efficacy of Aminophenylbutyric Acid Hydrochloride UR - ://WOS:000429407500048 VL - 8 ID - 2028 ER - TY - JOUR AB - Objective: To determine preliminary outcomes of targeted headache treatments provided at a novel outpatient acute care pediatric headache treatment center. Background: Limitations exist in acute management of pediatric headaches, including inadequate access to specialty headache therapies and headache specialists in acute settings, variable success of emergency room treatments, and omission of comfort measures. An outpatient acute headache care clinic (the "Headache Treatment Center") was strategically initiated at a Midwestern pediatric academic hospital to provide acute and targeted headache therapies for children with active headaches. Methods: We conducted a retrospective chart review of 154 visits from September through November 2018 of patients ages 7-18 years visiting the Headache Treatment Center. Results: On average, headache intensity (measured on an 11-point pain numeric rating scale) decreased after interventions used in the Headache Treatment Center (mean change = 2.85 +/- 2.81,P< .05, Cohend= 1.01). Large effect sizes for reducing headache intensity were observed for pericranial, occipital/auriculotemporal, and occipital nerve blocks, Cohend= 1.56, 1.64 and 1.02, respectively. Large effect sizes for reducing headache intensity also were observed for a transcutaneous supraorbital nerve stimulator device (Cefaly) (Cohend= 1.02), acupuncture (Cohend= 1.09), and intravenous migraine cocktails (Cohend= 0.91-1.34). Conclusion: Targeted headache therapies to abort pediatric primary headaches as part of a novel headache clinic model may be beneficial for short-term management. AN - WOS:000565698700001 AU - Esparham, A. AU - Boorigie, M. AU - Ablatt, S. AU - Connelly, M. AU - Bickel, J. C7 - 0883073820952997 DA - Jan DO - 10.1177/0883073820952997 IS - 1 N1 - Esparham, Anna Boorigie, Madeline Ablatt, Saniya Connelly, Mark Bickel, Jennifer 1708-8283 PY - 2021 SN - 0883-0738 SP - 54-59 ST - Improving Acute Treatment of Pediatric Primary Headache Disorders With a Novel Headache Treatment Center: Retrospective Review of Preliminary Outcomes T2 - Journal of Child Neurology TI - Improving Acute Treatment of Pediatric Primary Headache Disorders With a Novel Headache Treatment Center: Retrospective Review of Preliminary Outcomes UR - ://WOS:000565698700001 VL - 36 ID - 1800 ER - TY - JOUR AB - BACKGROUND: In recent years, great attention has been given to the presence of psychological problems and psychiatric comorbidity that are also present in children affected by primary headaches. The relationship between pain and attachment has been identified, and it may be that pain perception may change in relation with specific attachment styles. The aim of the present study was to assess the prevalent attachment style and verify its putative relationship and correlation with the main characteristics of migraine attacks, in school-aged children affected by migraine without aura (MoA). MATERIALS AND METHODS: The study population consisted of 219 children (103 males, 116 females) aged between 6 and 11 years (mean 8.96 ± 2.14 years), consecutively referred for MoA compared with 381 healthy controls (174 males, 207 females; mean age 9.01 ± 1.75 years) randomly selected from schools. All the children were classified according to the attachment typologies of the Italian modified version of the Separation Anxiety Test; monthly headache frequency and mean headache duration were assessed from daily headache diaries kept by all the children. Headache intensity was assessed on a visual analog scale. The chi-square test and t-test, where appropriate, were applied, and the Spearman rank correlation test was applied to explore the relationship between the types of attachment style and clinical aspects of MoA. RESULTS: The MoA group showed a significantly higher prevalence of type A (avoidant) attachment (P<0.001) and a significantly lower prevalence of type B (secure) attachment (P<0.001) compared with the control group. Moreover, the Spearman rank correlation analysis showed a significant relationship between MoA characteristics and the attachment style of MoA children. CONCLUSION: The main findings of the present study were the higher prevalence among MoA children of the avoidant attachment style (type A) and the significantly lower prevalence of the secure style attachment (type B) compared with the normal controls, suggesting that the study of psychiatric comorbidity in pediatric headache may be enriched by this new aspect of analysis. AD - Center for Childhood Headache, Clinic of Child and Adolescent Neuropsychiatry, Department of Mental Health, Physical and Preventive Medicine, Second University of Naples, Naples, Italy. AN - 24124370 AU - Esposito, M. AU - Parisi, L. AU - Gallai, B. AU - Marotta, R. AU - Di Dona, A. AU - Lavano, S. M. AU - Roccella, M. AU - Carotenuto, M. C2 - PMC3794987 DO - 10.2147/ndt.S52716 DP - NLM ET - 2013/10/15 KW - Separation Anxiety Test attachment style children migraine without aura LA - eng N1 - 1178-2021 Esposito, Maria Parisi, Lucia Gallai, Beatrice Marotta, Rosa Di Dona, Anna Lavano, Serena Marianna Roccella, Michele Carotenuto, Marco Journal Article Neuropsychiatr Dis Treat. 2013;9:1513-9. doi: 10.2147/NDT.S52716. Epub 2013 Oct 3. PY - 2013 SN - 1176-6328 (Print) 1176-6328 SP - 1513-9 ST - Attachment styles in children affected by migraine without aura T2 - Neuropsychiatr Dis Treat TI - Attachment styles in children affected by migraine without aura VL - 9 ID - 4127 ER - TY - JOUR AB - Background: The purpose of this study was to assess the cognitive functioning of children affected by headache, pinpointing the differences in intelligence style between subjects affected by migraine without aura and subjects with tension-type headache. Methods: The study population consisted of 147 children (mean age 10.82 +/- 2.17 years) with headache, recruited from the Headache Center for Developmental Age, Child and Adolescent Neuropsychiatry Clinic, Second University of Naples. Cognitive profiling was performed using Weschler Intelligence Scale for Children Third Edition throughout the sample. According to the International Classification of Headache Disorders II criteria for pediatric age, subjects were divided into a migraine without aura group (n = 75; 43 boys, 32 girls) and a tension-type headache group (n = 72; 49 boys, 23 girls). The results were compared with the findings obtained from a sample of 137 healthy control subjects recruited from schools in the Campania region, matched for age and gender. Results: No difference in full intelligence quotient was found between the groups, but the children with tension-type headache had a lower verbal intelligence quotient and a higher performance intelligence quotient than the healthy controls and children with migraine. Factor analysis data showed that the children with migraine seemed to have lower perceptual organization than the children affected by tension-type headache. Conclusion: To our knowledge, studies on cognitive functioning in children affected by headache in the interictal phase are scarce, and our results suggest a new perspective in understanding of the neuropsychological aspects of young patients affected by headaches. AN - WOS:000310429700001 AU - Esposito, M. AU - Pascotto, A. AU - Gallai, B. AU - Parisi, L. AU - Roccella, M. AU - Marotta, R. AU - Lavano, S. M. AU - Gritti, A. AU - Mazzotta, G. AU - Carotenuto, M. DO - 10.2147/ndt.S36863 N1 - Esposito, Maria Pascotto, Antonio Gallai, Beatrice Parisi, Lucia Roccella, Michele Marotta, Rosa Lavano, Serena Marianna Gritti, Antonella Mazzotta, Giovanni Carotenuto, Marco Marotta, Rosa/AAG-1453-2020 Marotta, Rosa/0000-0003-0515-5952; CAROTENUTO, Marco/0000-0002-8136-7597; ESPOSITO, Maria/0000-0001-7095-7957 1178-2021 PY - 2012 SP - 509-513 ST - Can headache impair intellectual abilities in children? An observational study T2 - Neuropsychiatric Disease and Treatment TI - Can headache impair intellectual abilities in children? An observational study UR - ://WOS:000310429700001 VL - 8 ID - 2455 ER - TY - JOUR AB - Background Sickle cell disease (SCD) is one of the commonest severe monogenic disorders in the world, due to the inheritance of two abnormal haemoglobin (beta globin) genes. SCD can cause severe pain, significant end-organ damage, pulmonary complications, and premature death. Silent cerebral infarcts are the commonest neurological complication in children and probably adults with SCD. Silent cerebral infarcts also affect academic performance, increase cognitive deficits and may lower intelligence quotient. Objectives To assess the effectiveness of interventions to reduce or prevent silent cerebral infarcts in people with SCD. Search methods We searched for relevant trials in the Cochrane Library, MEDLINE (from 1946), Embase (from 1974), the Transfusion Evidence Library (from 1980), and ongoing trial databases; all searches current to 19 September 2016. We searched the Cochrane Cystic Fibrosis and Genetic Disorders Group Trials Register: 06 October 2016. Selection criteria Randomised controlled trials comparing interventions to prevent silent cerebral infarcts in people with SCD. There were no restrictions by outcomes examined, language or publication status. Data collection and analysis We used standard Cochrane methodological procedures. Main results We included five trials (660 children or adolescents) published between 1998 and 2016. Four of the five trials were terminated early. The vast majority of participants had the haemoglobin (Hb) SS form of SCD. One trial focused on preventing silent cerebral infarcts or stroke; three trials were for primary stroke prevention and one trial dealt with secondary stroke prevention. Three trials compared the use of regular long-term red blood cell transfusions to standard care. Two of these trials included children with no previous long-term transfusions: one in children with normal transcranial doppler (TCD) velocities; and one in children with abnormal TCD velocities. The third trial included children and adolescents on long-term transfusion. Two trials compared the drug hydroxyurea and phlebotomy to long-term transfusions and iron chelation therapy: one in primary prevention (children), and one in secondary prevention (children and adolescents). The quality of the evidence was moderate to very low across different outcomes according to GRADE methodology. This was due to trials being at high risk of bias because they were unblinded; indirectness (available evidence was only for children with HbSS); and imprecise outcome estimates. Long-term red blood cell transfusions versus standard care Children with no previous long-term transfusions and higher risk of stroke (abnormal TCD velocities or previous history of silent cerebral infarcts) Long-term red blood cell transfusions may reduce the incidence of silent cerebral infarcts in children with abnormal TCD velocities, risk ratio (RR) 0.11 (95% confidence interval (CI) 0.02 to 0.86) (one trial, 124 participants, low-quality evidence); but make little or no difference to the incidence of silent cerebral infarcts in children with previous silent cerebral infarcts on magnetic resonance imaging and normal or conditional TCDs, RR 0.70 (95% CI 0.23 to 2.13) (one trial, 196 participants, low-quality evidence). No deaths were reported in either trial. Long-term red blood cell transfusions may reduce the incidence of: acute chest syndrome, RR 0.24 (95% CI 0.12 to 0.49) (two trials, 326 participants, low-quality evidence); and painful crisis, RR 0.63 (95% CI 0.42 to 0.95) (two trials, 326 participants, low-quality evidence); and probably reduces the incidence of clinical stroke, RR 0.12 (95% CI 0.03 to 0.49) (two trials, 326 participants, moderate-quality evidence). Long-term red blood cell transfusions may improve quality of life in children with previous silent cerebral infarcts (difference estimate -0.54; 95% confidence interval -0.92 to -0.17; one trial; 166 participants), but may have no effect on cognitive function (least squares means: 1.7, 95% CI -1.1 to 4.4) (one trial, 166 participants, low-quality evidence). Transfusions continued versus transfusions halted: children and adolescents with normalised TCD velocities (79 participants; one trial) Continuing red blood cell transfusions may reduce the incidence of silent cerebral infarcts, RR 0.29 (95% CI 0.09 to 0.97 (low-quality evidence). We are very uncertain whether continuing red blood cell transfusions has any effect on all-cause mortality, Peto odds ratio (OR) 8.00 (95% CI 0.16 to 404.12); or clinical stroke, RR 0.22 (95% CI 0.01 to 4.35) (very low-quality evidence). The trial did not report: comparative numbers for SCD-related adverse events; quality of life; or cognitive function. Hydroxyurea and phlebotomy versus transfusions and chelation Primary prevention, children (121 participants; one trial) We are very uncertain whether switching to hydroxyurea and phlebotomy has any effect on: silent cerebral infarcts (no infarcts); allcause mortality (no deaths); risk of stroke (no strokes); or SCD-related complications, RR 1.52 (95% CI 0.58 to 4.02) (very low-quality evidence). Secondary prevention, children and adolescents with a history of stroke (133 participants; one trial) We are very uncertain whether switching to hydroxyurea and phlebotomy has any effect on: silent cerebral infarcts, Peto OR 7.28 (95% CI 0.14 to 366.91); all-cause mortality, Peto OR 1.02 (95% CI 0.06 to 16.41); or clinical stroke, RR 14.78 (95% CI 0.86 to 253.66) (very low-quality evidence). Switching to hydroxyurea and phlebotomy may increase the risk of SCD-related complications, RR 3.10 (95% CI 1.42 to 6.75) (low-quality evidence). Neither trial reported on quality of life or cognitive function. Authors' conclusions We identified no trials for preventing silent cerebral infarcts in adults, or in children who do not have HbSS SCD. Long-term red blood cell transfusions may reduce the incidence of silent cerebral infarcts in children with abnormal TCD velocities, but may have little or no effect on children with normal TCD velocities. In children who are at higher risk of stroke and have not had previous long-term transfusions, long-term red blood cell transfusions probably reduce the risk of stroke, and other SCD-related complications (acute chest syndrome and painful crises). In children and adolescents at high risk of stroke whose TCD velocities have normalised, continuing red blood cell transfusions may reduce the risk of silent cerebral infarcts. No treatment duration threshold has been established for stopping transfusions. Switching to hydroxyurea with phlebotomy may increase the risk of silent cerebral infarcts and SCD-related serious adverse events in secondary stroke prevention. All other evidence in this review is of very low-quality. AN - WOS:000402520100026 AU - Estcourt, L. J. AU - Fortin, P. M. AU - Hopewell, S. AU - Trivella, M. AU - Doree, C. AU - Abboud, M. R. C7 - Unsp cd012389 DO - 10.1002/14651858.CD012389.pub2 IS - 5 N1 - Estcourt, Lise J. Fortin, Patricia M. Hopewell, Sally Trivella, Marialena Doree, Carolyn Abboud, Miguel R. Silva, Gisele/H-3082-2013 Trivella, Marialena/0000-0003-4492-1760; Estcourt, Lise/0000-0003-4309-9162 1361-6137 PY - 2017 SN - 1469-493X ST - Interventions for preventing silent cerebral infarcts in people with sickle cell disease T2 - Cochrane Database of Systematic Reviews TI - Interventions for preventing silent cerebral infarcts in people with sickle cell disease UR - ://WOS:000402520100026 ID - 2114 ER - TY - JOUR AB - Background Sickle cell disease (SCD) is one of the commonest severe monogenic disorders in the world, due to the inheritance of two abnormal haemoglobin (beta globin) genes. SCD can cause severe pain, significant end-organ damage, pulmonary complications, and premature death. Silent cerebral infarcts are the commonest neurological complication in children and probably adults with SCD. Silent cerebral infarcts also affect academic performance, increase cognitive deficits and may lower intelligence quotient. Objectives To assess the effectiveness of interventions to reduce or prevent silent cerebral infarcts in people with SCD. Search methods We searched for relevant trials in the Cochrane Library, MEDLINE (from 1946), Embase (from 1974), the Transfusion Evidence Library (from 1980), and ongoing trial databases; all searches current to 14 November 2019. We searched the Cochrane Cystic Fibrosis and Genetic Disorders Group Trials Register: 07 October 2019. Selection criteria Randomised controlled trials comparing interventions to prevent silent cerebral infarcts in people with SCD. There were no restrictions by outcomes examined, language or publication status. Data collection and analysis We used standard Cochrane methodological procedures. Main results We included five trials (660 children or adolescents) published between 1998 and 2016. Four of the five trials were terminated early. The vast majority of participants had the haemoglobin (Hb)SS form of SCD. One trial focused on preventing silent cerebral infarcts or stroke; three trials were for primary stroke prevention and one trial dealt with secondary stroke prevention. Three trials compared the use of regular long-term red blood cell transfusions to standard care. Two of these trials included children with no previous long-term transfusions: one in children with normal transcranial doppler (TCD) velocities; and one in children with abnormal TCD velocities. The third trial included children and adolescents on long-term transfusion. Two trials compared the drug hydroxyurea and phlebotomy to long-term transfusions and iron chelation therapy: one in primary prevention (children), and one in secondary prevention (children and adolescents). The quality of the evidence was moderate to very low across different outcomes according to GRADE methodology. This was due to trials being at high risk of bias because they were unblinded; indirectness (available evidence was only for children with HbSS); and imprecise outcome estimates. Long-term red blood cell transfusions versus standard care Children with no previous long-term transfusions and higher risk of stroke (abnormal TCD velocities or previous history of silent cerebral infarcts) Long-term red blood cell transfusions may reduce the incidence of silent cerebral infarcts in children with abnormal TCD velocities, risk ratio (RR) 0.11 (95% confidence interval (CI) 0.02 to 0.86) (one trial, 124 participants, low-quality evidence); but make little or no difference to the incidence of silent cerebral infarcts in children with previous silent cerebral infarcts on magnetic resonance imaging and normal or conditional TCDs, RR 0.70 (95% CI 0.23 to 2.13) (one trial, 196 participants, low-quality evidence). No deaths were reported in either trial. Long-term red blood cell transfusions may reduce the incidence of: acute chest syndrome, RR 0.24 (95% CI 0.12 to 0.49) (two trials, 326 participants, low-quality evidence); and painful crisis, RR 0.63 (95% CI 0.42 to 0.95) (two trials, 326 participants, low-quality evidence); and probably reduces the incidence of clinical stroke, RR 0.12 (95% CI 0.03 to 0.49) (two trials, 326 participants, moderate-quality evidence). Long-term red blood cell transfusions may improve quality of life in children with previous silent cerebral infarcts (difference estimate -0.54; 95% confidence interval -0.92 to -0.17; one trial; 166 participants), but may have no effect on cognitive function (least squares means: 1.7, 95% CI -1.1 to 4.4) (one trial, 166 participants, low-quality evidence). Transfusions continued versus transfusions halted: children and adolescents with normalised TCD velocities (79 participants; one trial) Continuing red blood cell transfusions may reduce the incidence of silent cerebral infarcts, RR 0.29 (95% CI 0.09 to 0.97 (low-quality evidence). We are very uncertain whether continuing red blood cell transfusions has any effect on all-cause mortality, Peto odds ratio (OR) 8.00 (95% CI 0.16 to 404.12); or clinical stroke, RR 0.22 (95% CI 0.01 to 4.35) (very low-quality evidence). The trial did not report: comparative numbers for SCD-related adverse events; quality of life; or cognitive function. Hydroxyurea and phlebotomy versus transfusions and chelation Primary prevention, children (121 participants; one trial) We are very uncertain whether switching to hydroxyurea and phlebotomy has any effect on: silent cerebral infarcts (no infarcts); all-cause mortality (no deaths); risk of stroke (no strokes); or SCD-related complications, RR 1.52 (95% CI 0.58 to 4.02) (very low-quality evidence). Secondary prevention, children and adolescents with a history of stroke (133 participants; one trial) We are very uncertain whether switching to hydroxyurea and phlebotomy has any effect on: silent cerebral infarcts, Peto OR 7.28 (95% CI 0.14 to 366.91); all-cause mortality, Peto OR 1.02 (95%CI 0.06 to 16.41); or clinical stroke, RR 14.78 (95% CI 0.86 to 253.66) (very lowquality evidence). Switching to hydroxyurea and phlebotomy may increase the risk of SCD-related complications, RR 3.10 (95% CI 1.42 to 6.75) (low-quality evidence). Neither trial reported on quality of life or cognitive function. Authors' conclusions We identified no trials for preventing silent cerebral infarcts in adults, or in children who do not have HbSS SCD. Long-term red blood cell transfusions may reduce the incidence of silent cerebral infarcts in children with abnormal TCD velocities, but may have little or no effect on children with normal TCD velocities. In children who are at higher risk of stroke and have not had previous longterm transfusions, long-term red blood cell transfusions probably reduce the risk of stroke, and other SCD-related complications (acute chest syndrome and painful crises). In children and adolescents at high risk of stroke whose TCD velocities have normalised, continuing red blood cell transfusions may reduce the risk of silent cerebral infarcts. No treatment duration threshold has been established for stopping transfusions. Switching to hydroxyurea with phlebotomy may increase the risk of silent cerebral infarcts and SCD-related serious adverse events in secondary stroke prevention. All other evidence in this review is of very low-quality. AN - WOS:000529866800056 AU - Estcourt, L. J. AU - Fortin, P. M. AU - Hopewell, S. AU - Trivella, M. AU - Doree, C. AU - Abboud, M. R. C7 - Cd012389 DO - 10.1002/14651858.CD012389.pub3 IS - 4 N1 - Estcourt, Lise J. Fortin, Patricia M. Hopewell, Sally Trivella, Marialena Doree, Carolyn Abboud, Miguel R. 1361-6137 PY - 2020 SN - 1469-493X ST - Interventions for preventing silent cerebral infarcts in people with sickle cell disease T2 - Cochrane Database of Systematic Reviews TI - Interventions for preventing silent cerebral infarcts in people with sickle cell disease UR - ://WOS:000529866800056 ID - 1858 ER - TY - JOUR AB - Background Previous studies on children's pain perspectives remain limited to English-speaking populations. Methods An exploratory cross-sectional descriptive design was used to investigate the developmental progression of children's pain perspectives, including their pain experience, its definition and attributes, causality and coping. The Children's Pain Perspectives Inventory was applied to 180 healthy Spanish children. A coding system was developed following the content analysis method. Three age groups were compared: 4-6 years, corresponding to the Piagetian pre-operational stage of cognitive development; 7-11 years, corresponding to stage of concrete operations; and 12-14 years, corresponding to the period of early formal operations. Results In children between 4 and 6, the predominant narratives related to physical injuries, the notion of causality and the definition of pain. In children between 7 and 11, the predominant narratives were those in which pain was described as a sensation in one part of the body. The view of pain as having an emotional basis significantly increased with age and was more frequent in adolescents. In contrast, children between 4-6 and 7-11 indicated that pain occurs spontaneously. The denial of any positive aspects of pain significantly decreased with age; some children between 7 and 11 referred to the 'possibility of relief', while the view that pain is a 'learning experience' was significantly more frequent among adolescents aged between 12 and 14 years. The use of cognitive strategies to control pain significantly increased with age. Between 12 and 14 years of age, adolescents communicate pain by non-verbal behaviour and reported that they do not express demands for relief. Conclusions There was a progression from concrete to more complex notions of pain as age increased. These results may be of use to health professionals and parents to understand how children at various developmental stages express and cope with pain and to develop tools that effectively assess and manage pain in children. AN - WOS:000302352300018 AU - Esteve, R. AU - Marquina-Aponte, V. DA - May DO - 10.1111/j.1365-2214.2011.01297.x IS - 3 N1 - Esteve, R. Marquina-Aponte, V. ESTEVE, ROSA/AAI-5285-2021; Zarazaga, M Rosa Esteve/G-1442-2011 Esteve, rosa/0000-0003-4474-7432; 1365-2214 PY - 2012 SN - 0305-1862 SP - 441-452 ST - Children's pain perspectives T2 - Child Care Health and Development TI - Children's pain perspectives UR - ://WOS:000302352300018 VL - 38 ID - 2442 ER - TY - JOUR AN - WOS:000398755400165 AU - Evans, J. AU - Hahn, A. AU - Hoehn, I. AU - Lemanek, K. DA - Apr DO - 10.1016/j.jpain.2017.02.152 IS - 4 N1 - Evans, J. Hahn, A. Hoehn, I. Lemanek, K. 1 PY - 2017 SN - 1526-5900 SP - S40-S41 ST - Somatization, Sleep, School Attendance, and Quality of Life as Predictors of Completing a Pediatric Pain Clinic T2 - Journal of Pain TI - Somatization, Sleep, School Attendance, and Quality of Life as Predictors of Completing a Pediatric Pain Clinic UR - ://WOS:000398755400165 VL - 18 ID - 2101 ER - TY - JOUR AB - Headache, in particular migraine, is one of the most frequent neurological symptoms in children and adolescents and it affects about 60% of children and adolescents all over the world. Headache can affect several areas of child's functioning, such as school, physical activities, peer, and family relationship. The global and severe burden of this disease requires a multidisciplinary strategy and an effective treatment addressed all of the patient's needs and based on cutting-edge scientific research. In recent years, research has focused on cognitive factors specifically in functions called metacognitive processes. Metacognition can be defined as the knowledge, beliefs, and cognitive processes involved in monitoring, control, and assessment of cognition. Metacognition seems to be closely related to the ability of theory of mind, the ability to infer, and reason about the mental states of other people in order to predict and explain own behavior. Recent studies found a relationship between metacognitive skills and anxiety, depression, motivation, academic performance, human social interactions, and stress symptoms. This relationship is very interesting for headache treatment, because these factors are the most commonly reported triggers in this disorder and there is a high comorbidity with anxiety and depression in children and adolescents with headache. So, headache and these comorbidities, in particular anxiety and depression, may have in common persistent and maladaptive patterns of thinking which are related to maladaptive metacognitive beliefs. Further research should assess metacognitive processes of children and adolescents with headache in order to increase their ability to control their own cognitive processes and consequently monitor factors which may trigger the attacks. AN - WOS:000418062600001 AU - Faedda, N. AU - Natalucci, G. AU - Calderoni, D. AU - Cerutti, R. AU - Verdecchia, P. AU - Guidetti, V. C7 - 650 DA - Dec DO - 10.3389/fneur.2017.00650 N1 - Faedda, Noemi Natalucci, Giulia Calderoni, Dario Cerutti, Rita Verdecchia, Paola Guidetti, Vincenzo PY - 2017 SN - 1664-2295 ST - Metacognition and Headache: which is the Role in Childhood and Adolescence? T2 - Frontiers in Neurology TI - Metacognition and Headache: which is the Role in Childhood and Adolescence? UR - ://WOS:000418062600001 VL - 8 ID - 2059 ER - TY - JOUR AB - PURPOSE OF REVIEW: Cancer pain remains inadequately treated, despite internationally accepted management guidelines and a myriad of treatment options. Risk factors for undertreatment are reviewed, along with possible explanations. Recent studies documenting the scope of the problem as well as investigating solutions are discussed with clinical-practice recommendations outlined. RECENT FINDINGS: Women over 65 years of age representative of a cultural minority, with earlier stage disease, cared for at home, and with high-school education or less are at highest risk of having uncontrolled cancer pain. Optimal treatment is impeded by patients' maladaptive beliefs, nonadherence, underreporting or miscommunication with caregivers; from a healthcare provider perspective, it may be due to inadequate assessment, documentation, knowledge, and communication. Emerging data support the vital influence of lay caregivers on appropriate pain management. Although home-education programs may decrease pain and improve quality of life, there are also less intensive approaches deliverable by individuals to holistically address pain. SUMMARY: Prospective study of barriers to both delivery and receipt of adequate pain management is needed, as the majority of published literature is based on survey studies. Treatment must be individualized based on clinical circumstances and patient wishes, with the goal of maximizing function and quality of life. AD - Department of Radiation Oncology, University of Alberta, Cross Cancer Institute, 11560 University Avenue, Edmonton, Alberta, Canada. alysa.fairchild@albertahealthservices.ca AN - 20040878 AU - Fairchild, A. DA - Mar DO - 10.1097/SPC.0b013e328336289c DP - NLM ET - 2009/12/31 IS - 1 KW - Aged Analgesics/*therapeutic use Female Health Knowledge, Attitudes, Practice Humans Medication Adherence Neoplasms/*complications Pain/*drug therapy/etiology Pain Measurement Patient Education as Topic Practice Patterns, Physicians' LA - eng N1 - 1751-4266 Fairchild, Alysa Journal Article Review United States Curr Opin Support Palliat Care. 2010 Mar;4(1):11-5. doi: 10.1097/SPC.0b013e328336289c. PY - 2010 SN - 1751-4258 SP - 11-5 ST - Under-treatment of cancer pain T2 - Curr Opin Support Palliat Care TI - Under-treatment of cancer pain VL - 4 ID - 4143 ER - TY - JOUR AB - Background: Caudal analgesia has been prolonged by the addition of various adjuvants. Dexmedetomidine is a highly selective alpha 2agonist with sedative and analgesic properties. Objective: To investigate the effect of addition of dexmedetomidine to 0.25% bupivacaine for caudal analgesia in children undergoing major abdominal cancer surgery. Study Design: A randomized double-blind trial. Setting: Academic medical center. Methods: Forty pediatric patients, aged 3 - 12 years, weighting 10 - 40 kg, and of American Society of Anesthesiologists (ASA) physical status I and II scheduled for major abdominal cancer surgeries under general anesthesia combined with caudal analgesia were enrolled. They were randomly allocated into 2 groups: Group I (BD): (n = 20) received 1 mL/kg bupivacaine 0.25% with dexmedetomidine 1 mu g/kg and group II (B): (n = 20) received 1 mL/kg bupivacaine 0.25%. Heart rate (HR), mean arterial pressure (MAP), and oxygen saturation (SPO2) were recorded for 120 minutes. Pain was assessed immediately postoperative and at hours 2, 4, 6, 12, 18, and 24 of postoperative period by Face, Legs, Activity, Cry and Consolability (FLACC) score. Time to first request for analgesia and total analgesic consumption [ Intravenous acetaminophen 15mg/kg (perfalgan, Squibb)] in the first 24 hours were recorded. The level of sedation was recorded using Ramsay's sedation scale. Adverse effects were recorded and treated. Results: There was significant reduction in FLACC score in group BD at 2, 4, 6, and 12 hours postoperatively compared to group B. At the eighteenth and twenty-fourth hour there was no significant difference. Time of the first rescue analgesic requirement was significantly prolonged in group BD compared to group B. The mean total consumption of rescue analgesia in the 24 hours of the postoperative period was significantly decreased in group BD (405.00 +/- 215.03) mg when compared with group B (810.35 +/- 200.93) mg. Limitations: This study is limited by its small sample size. Conclusion: Addition of dexmedetomidine (1 mu g/kg) to caudal bupivacaine 0.25% (1 mL/kg) in pediatric major abdominal cancer surgeries achieved significant postoperative pain relief for up to 19 hours, with less use of postoperative analgesics, and prolonged duration of arousable sedation. Hemodynamic changes were statistically significant, yet of no clinical significance. AN - WOS:000346033600018 AU - Fares, K. M. AU - Othman, A. H. AU - Alieldin, N. H. DA - Sep-Oct IS - 5 N1 - Fares, Khaled Mohamed Othman, Ahmed H. Alieldin, Nelly H. Fares, Khaled/AAD-8264-2021; Alieldin, Nelly/AAF-4872-2019 Fares, Khaled/0000-0003-3837-6436; Alieldin, Nelly/0000-0002-4778-3423 PY - 2014 SN - 1533-3159 SP - 393-400 ST - Efficacy and Safety of Dexmedetomidine Added to Caudal Bupivacaine in Pediatric Major Abdominal Cancer Surgery T2 - Pain Physician TI - Efficacy and Safety of Dexmedetomidine Added to Caudal Bupivacaine in Pediatric Major Abdominal Cancer Surgery UR - ://WOS:000346033600018 VL - 17 ID - 2288 ER - TY - JOUR AB - OBJECTIVE: Sleep deprivation can lower visceral perception thresholds and nonregenerative sleep has been implicated as an etiological factor in chronic hyperalgesia syndromes. The aims of our study were to quantify the self-reported prevalence and type of sleep disturbances in patients with different functional bowel disorders (FBD) and to determine if this prevalence is related to involvement of the upper or lower gastrointestinal (GI) tract, perceived disease severity, or psychological comorbidity. METHODS: We enrolled 505 new FBD patients from an academic referral center specializing in functional GI disorders and 247 community based healthy controls. All patients and controls were prospectively evaluated by validated bowel symptom and sleep questionnaires. A psychological profile was obtained by SCL-90R. RESULTS: We found that 68% of functional dyspepsia (FD), 71.2% of irritable bowel syndrome (IBS)+FD, 50.2% of IBS, and 55.1% of the normal subjects reported having sleep disturbances. Waking up repeatedly during the night and waking up in the morning feeling tired or not rested were the most commonly reported sleep patterns; 57.2% of the patients reported that their abdominal ache awakened them from sleep during the night. Self-reported sleep disturbance was directly related to the perceived intensity of GI symptoms. Self-reported sleep disturbances were equally common in both male (57%) and female (58.4%) FBD patients. There was no significant difference between the mean anxiety and depression scores between patients with and without sleep dysfunction. CONCLUSIONS: FD patients, but not IBS patients, reported sleep disturbances more frequently than healthy control subjects. Abdominal pain or discomfort that awaken FBD patients from sleep during the night were common, and thus a poor discriminating factor between organic and functional disorders. AD - UCLA/CURE Neuroenteric Disease Program, Department of Medicine, UCLA, Los Angeles, California, USA. AN - 10811327 AU - Fass, R. AU - Fullerton, S. AU - Tung, S. AU - Mayer, E. A. DA - May DO - 10.1111/j.1572-0241.2000.02009.x DP - NLM ET - 2000/05/16 IS - 5 KW - Abdominal Pain/complications Adolescent Adult Aged Aged, 80 and over Colonic Diseases, Functional/*complications/psychology Dyspepsia/*complications Female Humans Male Middle Aged Prospective Studies Sleep Wake Disorders/*etiology LA - eng N1 - Fass, R Fullerton, S Tung, S Mayer, E A Journal Article United States Am J Gastroenterol. 2000 May;95(5):1195-2000. doi: 10.1111/j.1572-0241.2000.02009.x. PY - 2000 SN - 0002-9270 (Print) 0002-9270 SP - 1195-2000 ST - Sleep disturbances in clinic patients with functional bowel disorders T2 - Am J Gastroenterol TI - Sleep disturbances in clinic patients with functional bowel disorders VL - 95 ID - 4031 ER - TY - JOUR AB - Background Anxiety and depression disorders in adolescents may affect their academic performances and social functioning at school. Adolescents with these disorders sometimes develop recurrent abdominal pain (RAP). Objective To assess the occurence of recurrent abdominal pain among adolescents with anxiety and depression disorders Methods We conducted a cross-sectional study from August to September 2009 in 12-18 year-old adolescents from 3 junior high schools and 3 senior high schools in Secanggang Subdistrict, Langkat District, North Sumatera Province. We screened 960 adolescents. Subjects were selected by consecutive sampling and instructed to fill the child behavior checklist (CBCL) and children's depression inventory (CDI) forms, Those with suspected anxiety/depression (CBCL score 12 for boys and 14 fir girls) and those with suspected depression (CDI score 13) were then examined by a psychiatrist. Adolescents diagnosed with anxiety or depression disorders were instructed to fill the RAP questionnaire based on Apley and Naish criteria. Results From the CBCL and CDI forms, 250 students were suspected of having anxiety and/or depression. From these, 144 students participated in this study. Of the 84 students with anxiety disorders, 60 (71.4%) students suffered from RAP. Of the 60 students with depression disorders, 31 (510) suffered from RAP Conclusion Adolescents with anxiety or depression are more likely to have recurrent abdominal pain. AN - WOS:000217027200004 AU - Fastralina AU - Sofyani, S. AU - Simbolon, M. J. AU - Lubis, I. Z. DA - Jan IS - 1 N1 - Fastralina Sofyani, Sri Simbolon, M. Joesoef Lubis, Iskandar Z. PY - 2013 SN - 0030-9311 SP - 16-20 ST - Recurrent abdominal pain in adolescents with anxiety and depression disorders T2 - Paediatrica Indonesiana TI - Recurrent abdominal pain in adolescents with anxiety and depression disorders UR - ://WOS:000217027200004 VL - 53 ID - 2403 ER - TY - JOUR AB - This study investigated recurrent abdominal pain in all 494 second-year infant children in a new town using a postal questionnaire followed by sampling and detailed interview. A prevalence of between 24.5 and 26.9% was found and there were associations with psychiatric deviance both at home and at school. There were also associations with social support of the mother, difficulties in settling into school and status of house ownership. Details of parental management of their children's symptoms are described. AN - 3958079 AU - Faull, C. AU - Nicol, A. R. DA - Mar DP - NLM ET - 1986/03/01 IS - 2 KW - *Abdomen Child Child, Preschool Family Humans Maternal Behavior Mental Disorders/complications Pain/complications/*epidemiology Population Dynamics Recurrence Schools Social Support United Kingdom LA - eng N1 - Faull, C Nicol, A R Journal Article England J Child Psychol Psychiatry. 1986 Mar;27(2):251-60. PY - 1986 SN - 0021-9630 (Print) 0021-9630 SP - 251-60 ST - Abdominal pain in six-year-olds: an epidemiological study in a new town T2 - J Child Psychol Psychiatry TI - Abdominal pain in six-year-olds: an epidemiological study in a new town VL - 27 ID - 3336 ER - TY - JOUR AB - Introduction: Subjective health complaints are common among children as well. Age, gender, health status, etc. can modify the prevalence, intensity, frequency and the dimensions of the psychosomatic complaints. Aim: The main purposes were to analyse the frequency pattern of psychosomatic complaints in children as well as to study the influence of physical status and lifestyle factors on psychosomatic status. Method: The subjects of the present analysis represented a random sample of the Hungarian National Growth Study (n = 13 331; 8-17-year-old). The three clusters of the health complaints were somatic, psychological and sleeping disorders. The psychosomatic status of 8-17-year-old children was analysed by dividing them into subgroups of experiencing the subjective health complaints often (weekly or more often), on an average level or rarely. Frequency distributions were examined for each subjective health complaint. Multinomial logistic regression analysis was applied to reveal the relationship between the frequency pattern of psychosomatic complaints and the hypothesized predictive factors. Results: The prevalence of the psychosomatic complaints increased by age, and girls reported more symptoms than boys. Subjective health status, nutritional status, body image, academic achievement, stature, body mass and socioeconomic status influenced the frequency pattern of psychosomatic complaints in girls, while physical activity, self-esteem, socioeconomic status and subjective health status in boys. Conclusions: Age, gender, socioeconomic status and psychosocial status can affect the frequency pattern of the psychosomatic complaints. AN - WOS:000461336700004 AU - Feher, P. AU - Annar, D. AU - Zsakai, A. AU - Bodzsar, E. DA - Mar DO - 10.1556/650.2019.31366 IS - 12 N1 - Feher Piroska Annar Dorina Zsakai Annamaria Bodzsar Eva Zsakai, Annamaria/AAE-8639-2020 Zsakai, Annamaria/0000-0001-8880-2056 1788-6120 PY - 2019 SN - 0030-6002 SP - 464-472 ST - The prevalence of psychosomatic complaints among 8-17-year-old Hungarian children T2 - Orvosi Hetilap TI - The prevalence of psychosomatic complaints among 8-17-year-old Hungarian children UR - ://WOS:000461336700004 VL - 160 ID - 1944 ER - TY - JOUR AB - PURPOSE: Claudication patients' perceptions of walking impairment often influence recommendations for peripheral bypass and angioplasty. The actual relationship between lower extremity blood flow and physical functioning, however, has rarely been explicitly studied. METHODS: Patients were enrolled at a visit to one of 16 vascular surgery offices and clinics that participated in a prospective outcomes study. A total of 555 patients (445 men and 110 women) with an abnormal ankle-brachial index (ABI), none of whom had had previous leg revascularization or symptoms of rest pain, skin ulcers, or gangrene, completed the SF36 Health Survey and the Peripheral Arterial Disease Walking Impairment Questionnaire (WIQ). Stepwise multiple regression analysis was used to test the statistical significance and strength of association between patients' ABI level and SF36 physical functioning (PF) and WIQ community walking distance scores, controlled for sociodemographic characteristics and the presence and severity of comorbid conditions. RESULTS: Univariate correlations with ABI were modest but significant (PF score, r = 0.12, p = 0.004; WIQ distance score, r = 0.18, p < 0.001). ABI was a very significant predictor of both PF (b = 18.8; p = 0.001) and WIQ scores (b = 0.33; p < 0.0001) in the multiple regression analysis. Other positive predictors of PF scores were high-school graduation and male sex. Negative predictors of PF scores were heart, lung, and cerebrovascular disease; knee arthritis and chronic back pain; and enrollment at a Veterans Administration clinic rather than a private community or academic office. CONCLUSION: Cross-sectional findings indicate that a 0.3 improvement in ABI is associated with an average improvement of 5.6% in PF or 10.3% in WIQ distance score. However, proper selection of individual candidates for interventional therapy, that is, those patients who have lower ABIs, lower initial functioning, and fewer disabling comorbidities would be predicted to produce a much greater functional benefit. Surgeons should make a rigorous functional evaluation when recommending interventional management of claudication. AD - Division of General Internal Medicine, Northwestern University Medical School, Chicago, IL 60611, USA. AN - 8911399 AU - Feinglass, J. AU - McCarthy, W. J. AU - Slavensky, R. AU - Manheim, L. M. AU - Martin, G. J. DA - Oct DO - 10.1016/s0741-5214(96)70066-6 DP - NLM ET - 1996/10/01 IS - 4 KW - Aged *Blood Pressure Comorbidity Female Humans Intermittent Claudication/complications/*physiopathology Leg/*blood supply Male Middle Aged Prospective Studies Regression Analysis Socioeconomic Factors Surveys and Questionnaires *Walking LA - eng N1 - Feinglass, J McCarthy, W J Slavensky, R Manheim, L M Martin, G J HS07184/HS/AHRQ HHS/United States Journal Article Multicenter Study Research Support, U.S. Gov't, P.H.S. United States J Vasc Surg. 1996 Oct;24(4):503-11; discussion 511-2. doi: 10.1016/s0741-5214(96)70066-6. PY - 1996 SN - 0741-5214 (Print) 0741-5214 SP - 503-11; discussion 511-2 ST - Effect of lower extremity blood pressure on physical functioning in patients who have intermittent claudication. The Chicago Claudication Outcomes Research Group T2 - J Vasc Surg TI - Effect of lower extremity blood pressure on physical functioning in patients who have intermittent claudication. The Chicago Claudication Outcomes Research Group VL - 24 ID - 4053 ER - TY - JOUR AB - Objectives To assess the association between bullying behavior and a wide variety of psychosomatic health complaints and depression. Study design in a cross-sectional study, 2766 elementary school children age 9 to 12 years filled out a questionnaire on bullying behavior and health complaints. Three groups-bullied children, active bullies, and children who both bully and are bullied-were compared with the group of children not involved in bullying behavior. Subsequently, risks for psychosomatic symptoms and depression were calculated by means of odds ratios. Results Bully victims had significantly higher chances for depression and psychosomatic symptoms compared with children not involved in bullying behavior. Odds ratios were as follows: headache, 3.0; sleeping problems, 2.4; abdominal pain, 3.2; bedwetting, 2.9; feeling tired, 3.4; and depression, 7.7. Children who actively bullied did not have a higher chance for most of the investigated health symptoms. Conclusions Being bullied is strongly associated with a wide range of psychosomatic symptoms and depression. These associations are similar to the complaints known to be associated with child abuse. Therefore, when such health complaints are presented, pediatricians and other health care workers should also be aware of the possibility that a child is being bullied to take preventive measures. AN - WOS:000188091100005 AU - Fekkes, M. AU - Pijpers, F. I. M. AU - Verloove-Vanhorick, S. P. DA - Jan DO - 10.1016/j.jpeds.2003.09.025 IS - 1 N1 - Fekkes, M Pijpers, FIM Verloove-Vanhorick, SP 1097-6833 PY - 2004 SN - 0022-3476 SP - 17-22 ST - Bullying behavior and associations with psychosomatic complaints and depression in victims T2 - Journal of Pediatrics TI - Bullying behavior and associations with psychosomatic complaints and depression in victims UR - ://WOS:000188091100005 VL - 144 ID - 2798 ER - TY - JOUR AB - Study Design. A prospective, repeated-measures cohort design with high school students from Montreal, Canada. Objectives. To determine whether smoking was a risk factor for the development of low back pain or other musculoskeletal pain in a cohort of adolescents. Summary of Background Data. Smoking has been associated with low back pain in adults. Many adolescents smoke, and the prevalence of low back pain in this age group is 30%. A history of low back pain is predictive of future problems. Methods. A total of 502 students from grades 7 to 9 were assessed from 3 schools. Data were collected at 3 times: at the beginning of the study, at 6 months, and at the end of a 12-month period. Students responded to a questionnaire addressing musculoskeletal health and lifestyle factors, which included smoking. Measurements of height, weight, trunk and leg flexibility, and trunk strength were obtained. Low back pain occurring at a frequency of at least once a week in the past 6 months was defined as the outcome. Multivariate methods were used to model the repeated-measures dichotomous outcome as a function of smoking and other covariates. Results. Smokers experienced low back pain more than nonsmokers (odds ratio, 2.4; 95% confidence interval, 1.3-6.0). There was also a dose-response relationship between amount smoked and development of low back pain. Smokers tended to experience more upper limb or lower limb pain than nonsmokers, although this result was not significant. Conclusions. Smoking was found to increase the risk for low back pain in this cohort of adolescents. AN - WOS:000084169700010 AU - Feldman, D. E. AU - Rossignol, M. AU - Shrier, L. AU - Abenhaim, L. DA - Dec DO - 10.1097/00007632-199912010-00011 IS - 23 N1 - Feldman, DE Rossignol, M Shrier, L Abenhaim, L PY - 1999 SN - 0362-2436 SP - 2492-2496 ST - Smoking - A risk factor for development of low back pain in adolescents T2 - Spine TI - Smoking - A risk factor for development of low back pain in adolescents UR - ://WOS:000084169700010 VL - 24 ID - 2874 ER - TY - JOUR AB - The impact of cerebrovascular events (CVE) on cognitive functioning in adults with sickle cell disease is not well understood. Sequelae of CVEs can adversely impact their quality of life. We reviewed neurocognitive presentation and testing in adults with sickle cell disease. We evaluated the frequency of complaints of memory disturbance using survey methodology in a sample of 109 adult patients with sickle cell disease (48 males, 61 females). A subsample of 24 patients also received a memory questionnaire where specific cognitive functions were assessed. Overall, we found that males and females did not differ in the frequency of experienced memory disturbance during painful crises. However, the frequency of men reporting that their ability to remember where they place common objects such as keys (p = 0.017) and remembering the item they intended to buy in a grocery store or pharmacy (p = 0.048) was worse now compared to when they were in high school and was greater when compared to women. The frequency of men who reported their memory was worse now than when they were in high school (p = 0.051) was also greater than in women. We concluded that memory dysfunction predicts global monthly presentation of pain. We suggest incorporating cost-effective neurocognitive screening measures as a standard of practice in sickle cell disease. AD - Department of Psychiatry, Duke University Medical Center, Durham, North Carolina 27705, USA. feliu001@mc.duke.edu AN - 22035043 AU - Feliu, M. H. AU - Crawford, R. D. AU - Edwards, L. AU - Wellington, C. AU - Wood, M. AU - Whitfield, K. E. AU - Edwards, C. L. DO - 10.3109/03630269.2011.626098 DP - NLM ET - 2011/11/01 IS - 5-6 KW - Adolescent Adult Anemia, Sickle Cell/*complications Cognition Disorders/complications/*epidemiology Female Humans Male Middle Aged Surveys and Questionnaires Young Adult LA - eng N1 - 1532-432x Feliu, Miriam H Crawford, Regina D Edwards, Lekisha Wellington, Chante Wood, Mary Whitfield, Keith E Edwards, Christopher L Journal Article England Hemoglobin. 2011;35(5-6):476-84. doi: 10.3109/03630269.2011.626098. Epub 2011 Oct 28. PY - 2011 SN - 0363-0269 SP - 476-84 ST - Neurocognitive testing and functioning in adults sickle cell disease T2 - Hemoglobin TI - Neurocognitive testing and functioning in adults sickle cell disease VL - 35 ID - 3970 ER - TY - JOUR AB - This population-based cross-sectional study examined the 3-month prevalence of headache, migraine and tension-type headache (TTH) among adolescents aged 12-15 years in Germany. Students (n = 3324) from 20 schools completed a questionnaire on general and headache-specific pain which included a sociodemographic module. The headache-specific questionnaire complied with the respective revised criteria of the International Headache Society (IHS). 'Modified criteria' changed the item 'duration' in migraine (>30 min instead of > 4 h). The overall 3-month prevalence of headache was 69.4% (boys 59.5%, girls 78.9%), with 4.4% of the adolescents suffering from frequent (>or=14 days/3 months) and severe (grade 8-10 on a 10-point visual analogue scale) headache and 1.4% (boys 0.9%, girls 1.9%) from headache >or= 15 days/month. The 3-month prevalence of migraine was 2.6% (boys 1.6%, girls 3.5%) applying strict IHS criteria and 6.9% (boys 4.4%, girls 9.3%) with modified criteria; 12.6% (boys 8.3%, girls 16.7%) suffered from probable migraine, 0.07% fulfilled the criteria for chronic migraine, 4.5% (boys 4.6%, girls 4.3%) suffered from TTH, 0.2% from chronic TTH and 15.7% (boys 14.5%, girls 16.9%) from probable TTH. Headache and migraine were more common in girls than in boys and in teenagers, especially in girls, aiming at higher education. Recurrent headache and primary headache disorders are common complaints among German adolescents, especially among girls. AD - Institute for Community Medicine, Section Epidemiology of Health Care and Community Health, University of Greifswald, Greifswald, Germany. AN - 17376112 AU - Fendrich, K. AU - Vennemann, M. AU - Pfaffenrath, V. AU - Evers, S. AU - May, A. AU - Berger, K. AU - Hoffmann, W. DA - Apr DO - 10.1111/j.1468-2982.2007.01289.x DP - NLM ET - 2007/03/23 IS - 4 KW - Adolescent Comorbidity Female Germany/epidemiology Headache/*diagnosis/*epidemiology Humans Male Migraine Disorders/*diagnosis/*epidemiology Prevalence Risk Assessment/methods Risk Factors Students/*statistics & numerical data Tension-Type Headache/*diagnosis/*epidemiology LA - eng N1 - Fendrich, K Vennemann, M Pfaffenrath, V Evers, S May, A Berger, K Hoffmann, W Journal Article Research Support, Non-U.S. Gov't England Cephalalgia. 2007 Apr;27(4):347-54. doi: 10.1111/j.1468-2982.2007.01289.x. PY - 2007 SN - 0333-1024 (Print) 0333-1024 SP - 347-54 ST - Headache prevalence among adolescents--the German DMKG headache study T2 - Cephalalgia TI - Headache prevalence among adolescents--the German DMKG headache study VL - 27 ID - 3337 ER - TY - JOUR AB - Background: Children with sickle cell disease (SCD) may present oral conditions that can compromise children's health even more. However, there is still no consensus on the association between SCD and dental caries. The aim of this study was to assess caries prevalence in children with sickle cell disease (SCD), and the association of dental caries with socioeconomic factors, disease severity, and oral-health related to quality of life (OHRQoL). Methods: The sample was comprised of 106 children with SCD aged 8 to 14 years who were attending the Center for Hematology (Hemominas) in Belo Horizonte, Brazil. They were matched to 385 healthy peers. Data collection included interviews with guardians concerning SCD characteristics, and previous social and oral examinations to determine the caries prevalence. Caries prevalence as measured through the Decayed, Missing and Filled (dmft and DMFT) indices. OHRQoL was evaluated through the Brazilian versions of the Child Perceptions Questionnaires (CPQ(8-10), and CPQ(11-14) short-form version). Statistical analyses were performed using the chi-square test or Fisher`s exact test and the Mann Whitney test, as well as linear regression. Results: The DMFT index was 1.3 (SD: 2.1) in younger children with SCD and 1.5 (SD: 1.9) in SCD teens. Younger children with SCD had lower caries experience compared to healthy peers (p = .03). The experience of dental caries among teens with SCD was similar to healthy peers (p > 0.05). In addition, we did not see a significant difference on the mean overall scores of CPQ(8-10) between SCD younger children and controls. There was no statistically significant difference in the mean overall scores of teens CPQ11-14 between SCD and the control group. Socioeconomic variables were not associated with dental caries in the participants with SCD. However, SCD severity was associated with higher DMFT indexes (p < 0.05). Conclusions: Younger children with SCD had a low experience of dental caries. The dental caries experience in teenagers with SCD was similar to their healthy peers. OHRQoL was similar between SCD participants and controls. AN - WOS:000356571300001 AU - Fernandes, Mlmf AU - Kawachi, I. AU - Correa-Faria, P. AU - Pattusi, M. P. AU - Paiva, S. M. AU - Pordeus, I. A. C7 - 68 DA - Jun DO - 10.1186/s12903-015-0052-4 N1 - Matta Felisberto Fernandes, Maria Luiza Kawachi, Ichiro Correa-Faria, Patricia Pattusi, Marcos Pascoal Paiva, Saul Martins Pordeus, Isabela Almeida PORDEUS, ISABELA A/B-1570-2013; Paiva, Saul Martins/H-5757-2012; de Faria, Patricia Correa/N-9428-2013 PORDEUS, ISABELA A/0000-0002-5902-7481; Paiva, Saul Martins/0000-0002-3968-1638; de Faria, Patricia Correa/0000-0002-0528-1425 PY - 2015 SN - 1472-6831 ST - Caries prevalence and impact on oral health-related quality of life in children with sickle cell disease: cross-sectional study T2 - Bmc Oral Health TI - Caries prevalence and impact on oral health-related quality of life in children with sickle cell disease: cross-sectional study UR - ://WOS:000356571300001 VL - 15 ID - 2231 ER - TY - JOUR AB - BACKGROUND: A large number of patients with sickle cell anaemia are seen at the Medical College, Calicut from among the tribals and Chetti communities of the adjacent Wayanad district. We carried out a population-based study of gene frequencies and disease characteristics to plan an appropriate intervention. METHODS: Clinical examination and haemoglobin electrophoresis were done in 1016 subjects belonging to the tribal and Chetti communities in Wayanad district, by visiting hamlets and schools and evaluating everyone present at the time of the visit. RESULTS: The gene frequency of haemoglobin S ranged from 0.019 in Kattunayakan to 0.196 in Wayanadan Chettis. Wayanadan Chettis, Kurumas and Adiyas showed a high number of homozygotes with the oldest being 48 years. The survival of homozygotes is longer than what is generally recorded in other states. The disease was mild in 52.2% of cases. Painful crises were found in 43.5% and splenomegaly and leg ulcers in 4.3% each. The mean haemoglobin F rate in homozygotes was 25.9%. It was higher in clinically mild cases and in those showing an absence of irreversible sickle cells in the peripheral smear. CONCLUSIONS: The survival of patients with sickle cell anaemia seems to be higher in Kerala as compared to other states. It appears that even small improvements in primary health care available to the population (as in Kerala) are sufficient to achieve this effect. Integration of disease diagnosis and management into the already existing health care delivery system may lead to even better survival and quality of life. AD - Department of Pathology, Medical College, Kerala, India. AN - 11767218 AU - Feroze, M. AU - Aravindan, K. P. DA - Sep-Oct DP - NLM ET - 2002/01/05 IS - 5 KW - Adolescent Adult Child Child, Preschool Female Gene Frequency/*genetics Genotype Hemoglobin SC Disease/epidemiology/*genetics Homozygote Humans India/epidemiology Male Middle Aged Prevalence LA - eng N1 - Feroze, M Aravindan, K P Journal Article Research Support, Non-U.S. Gov't India Natl Med J India. 2001 Sep-Oct;14(5):267-70. PY - 2001 SN - 0970-258X (Print) 0970-258x SP - 267-70 ST - Sickle cell disease in Wayanad, Kerala: gene frequencies and disease characteristics T2 - Natl Med J India TI - Sickle cell disease in Wayanad, Kerala: gene frequencies and disease characteristics VL - 14 ID - 3818 ER - TY - JOUR AB - OBJECTIVE: To study the outcome of two different forms of relaxation training administered by school nurses to adolescents suffering from recurrent headaches in an effectiveness study. METHODS: A total of 11 school nurses were randomized to administer one of the two treatments to 63 adolescents. A post hoc group with 42 untreated subjects, matched for headache diagnosis, sex, and age were included as a control group. RESULTS: The results showed no pre-post differences in headache reduction between the treatment groups, however, subjects treated with either of the two relaxation approaches were significantly more improved than those in the post hoc group on total headache activity and headache-free days. Clinical improvement (at least 50% improvement) was attained among 19% of the treated subjects as compared to 7% for those in the post hoc group, a nonsignificant difference. Higher functional disability predicted a worse outcome, and positive self-statements predicted better outcome. Altogether, these variables accounted for 29% of the outcome variance in the total headache activity. CONCLUSIONS: In the present study, outcomes of relaxation training as administered by school nurses were not found to be as powerful as similar treatments provided for adolescents with migraine or tension-type headache in the previous controlled studies of clinic as well as school samples. It is likely that the school nurses need to be more thoroughly trained and informed to achieve cost-effective improvement. Presently, it is suggested that the relaxation training should not be used as a part of regular treatment in the school health care for adolescents with recurrent headaches until further evidence is provided. AU - Fichtel, Asa AU - Larsson, Bo DA - 2004/06// DO - 10.1111/j.1526-4610.2004.446002.x DP - PubMed IS - 6 J2 - Headache KW - Adaptation, Psychological Adolescent Humans Migraine Disorders Recurrence Relaxation Therapy School Nursing Tension-Type Headache Treatment Outcome LA - eng PY - 2004 SN - 0017-8748 SP - 545-554 ST - Relaxation treatment administered by school nurses to adolescents with recurrent headaches T2 - Headache TI - Relaxation treatment administered by school nurses to adolescents with recurrent headaches UR - http://www.ncbi.nlm.nih.gov/pubmed/15186298 VL - 44 ID - 136 ER - TY - JOUR AB - Objective. The aim of this study was to develop a multidimensional assessment instrument named "Juvenile Vasculitis Multidimensional Assessment Report" (J-VAMAR) to measure all the domains of the vasculitis. In this qualitative study, it is primarily aimed to enrich the item generation for the J-VAMAR. Methods. Twelve children with vasculitis and their mothers (n=12) were enrolled in this study. The data were collected using both a demographic data form and a semi-structured interview form. The study was performed on individual patient face-to face interview. Data were analysed by grounded theory and the N Vivo 9 software program. Results. Four categories were obtained. These categories were (i) physical effects of the illness, (ii) emotional effects of the illness, (iii) social effects of the illness and (iv) experienced challenges related to treatment process. In the physical effect category severe pain, physical limitations, weakness and fatigue; in emotional effect category thought of death, hopelessness and dissatisfaction about body image; in the social effects category decrease in academic performance, absenteeism to school and concealing the sickness from friends were the most common features. In the fourth category, subjects complained of lifelong drug use and frequency of daily drug consumptions. Conclusion. These results provide evidence-based data for the assessment of children with vasculitis by several domains including physical, emotional and social aspects as well as treatment protocols. The study provides the basis and/or justification for selecting the domains that the developing multidimensional instrument should include. AN - WOS:000337069400024 AU - Fidanci, B. E. AU - Demirkaya, E. AU - Acikel, C. AU - Fidanci, K. AU - Karaman, D. AU - Yildiz, D. AU - Konukbay, D. AU - Polat, A. AU - Basbozkurt, G. AU - Topaloglu, R. AU - Cimaz, R. AU - Ravelli, A. AU - Ozen, S. AU - Dis, F. M. F. Arthrit Vasculitis Orphan DA - May-Jun IS - 2 N1 - Fidanci, B. E. Demirkaya, E. Acikel, C. Fidanci, K. Karaman, D. Yildiz, D. Konukbay, D. Polat, A. Basbozkurt, G. Topaloglu, R. Cimaz, R. Ravelli, A. Ozen, S. TOPALOGLU, Rezan/I-9095-2013; CIMAZ, Rolando/AAA-9058-2019; Basbozkurt, Gokalp/AAD-8524-2019; OZEN, SEZA/I-9096-2013; Demirkaya, Erkan/F-5082-2019; RAVELLI, ANGELO/J-8161-2016 CIMAZ, Rolando/0000-0002-3260-4226; Demirkaya, Erkan/0000-0003-4525-1789; RAVELLI, ANGELO/0000-0001-9658-0385 82 PY - 2014 SN - 0392-856X SP - S122-S127 ST - The invisible part of the iceberg: qualitative aspects of childhood vasculitis T2 - Clinical and Experimental Rheumatology TI - The invisible part of the iceberg: qualitative aspects of childhood vasculitis UR - ://WOS:000337069400024 VL - 32 ID - 2306 ER - TY - JOUR AB - PURPOSE: Approximately one third of adolescents in the United States report experiencing frequent headaches and stomachaches. We examined the association of psychosocial and physical factors with the report of weekly headaches or stomachaches using a representative sample of US teens. METHODS: Data for this project are from the survey of Health Behavior in School-Aged Children (HBSC), 2005-2006, a nationally representative sample of students in grades 6-10 in the United States. The total sample includes 12,070 students aged 11-17. Using logistic regression we modeled chronic headache and stomachache separately with the same set of physical predictors (dieting and substance use habits) and psychosocial predictors (attitudes towards self-image, peers, and family) along with demographic controls. RESULTS: Almost 20% of respondents experienced headaches weekly, and 12% experienced abdominal pain. Both physical and psychosocial factors were predictive of chronic symptoms. Increased substance usage and unhealthy eating practices were associated with the likelihood of experiencing both headaches and stomachaches. Negative self-image, family relationships, and school life were also predictive of symptom frequency. CONCLUSION: Headaches and stomachaches are associated with poor eating and substance use habits, as well as problems with self-image or social relationships among adolescents. For health care professionals, a holistic approach is needed to effectively address symptoms and prevent long-term health problems. AD - Department of Sociology, Brigham Young University, Provo, UT,United States of America. AN - 27665418 AU - Fife, B. AU - Forste, R. DA - Sep 26 DO - 10.1515/ijamh-2016-0062 DP - NLM ET - 2016/09/26 IS - 3 KW - United States early adolescents headache stomachache LA - eng N1 - 2191-0278 Fife, Benjamin Forste, Renata Journal Article Germany Int J Adolesc Med Health. 2016 Sep 26;30(3):/j/ijamh.2018.30.issue-3/ijamh-2016-0062/ijamh-2016-0062.xml. doi: 10.1515/ijamh-2016-0062. PY - 2016 SN - 0334-0139 ST - Physical and social factors associated with early adolescent headache and stomachache pain T2 - Int J Adolesc Med Health TI - Physical and social factors associated with early adolescent headache and stomachache pain VL - 30 ID - 4107 ER - TY - JOUR AB - Functional abdominal pain disorders (FAPD) are the most common chronic pain conditions in pediatric gastroenterology. They account for 50% of all pediatric gastroenterology clinic visits. The pathophysiology of FAPDs is poorly understood, but there is growing understanding of the role of food and the patient's nutritional state in both their treatment and prognosis. Clinic-based studies have shown a higher prevalence of FAPDs, and worse prognosis among obese children with FAPDs. We aimed to assess the nutritional status of children with FAPD to determine if there is increased prevalence of FAPDs in obese or underweight patients. We conducted a cross sectional study of schoolchildren in Colombia. We enrolled 1030 patients from five schools and screened them for FAPDs using Rome IV criteria. Data on weight, height, abdominal circumference and BMI were collected for each child. Cases (FAPDs) were compared with a control group of enrolled children who did not meet diagnostic criteria for any functional gastrointestinal disorders (FGID). We diagnosed 58 (5.8%) children with FAPDs based on Rome IV criteria. When we compared to participants who were not diagnosed with FGIDs by screening, there was no statistically significant difference in children who were obese (OR 0.34 CI: 0.03-1.34, p = 0.124) or overweight (OR 1.00 CI: 0.46-2.02, p = 0.984) or those with increased abdominal circumference (OR 0.94, CI: 0.10-3.90, p = 0.943). FAPDs are not more common among obese children compared with healthy controls at a community level. Obese children may have been overrepresented in previous studies which were done at a clinical level due to comorbidities and a more severe phenotype that makes them more likely to consult. Nutritional status is not a useful predictor for the occurrence of FAPDs in children in the general population. AD - Department of Pediatric Gastroenterology, Hepatology and Nutrition, University of Miami/Miller School of Medicine, Miami, FL 33136, USA. Department of Pediatrics, Universidad del Valle, Cali 760001, Colombia. AN - 32846953 AU - Fifi, A. C. AU - Velasco-Benitez, C. AU - Saps, M. C2 - PMC7551899 DA - Aug 24 DO - 10.3390/nu12092559 DP - NLM ET - 2020/08/28 IS - 9 KW - Abdominal Pain/*epidemiology/physiopathology Adolescent Child Colombia/epidemiology Comorbidity Cross-Sectional Studies Female Humans Male *Nutritional Status Overweight/*epidemiology/physiopathology Prevalence Schools Thinness/*epidemiology/physiopathology functional abdominal pain functional dyspepsia functional gastrointestinal disorders irritable bowel syndrome obesity LA - eng N1 - 2072-6643 Fifi, Amanda C Velasco-Benitez, Carlos Orcid: 0000-0002-4062-5326 Saps, Miguel Journal Article Nutrients. 2020 Aug 24;12(9):2559. doi: 10.3390/nu12092559. PY - 2020 SN - 2072-6643 ST - Functional Abdominal Pain and Nutritional Status of Children. A School-Based Study T2 - Nutrients TI - Functional Abdominal Pain and Nutritional Status of Children. A School-Based Study VL - 12 ID - 3904 ER - TY - JOUR AB - Purpose The clinical outcomes and complications of tension-band plating have been well documented, and commonly include a post-operative delay in return of function. We performed a retrospective comparison study to evaluate the capacity of immediate post-operative physical therapy to prevent this post-operative delay in return of function. Methods Sixty-seven consecutive growth-deformity patients who were treated with tension-band plating at a single institution fulfilled the study criteria. Patients were allocated into two treatment groups: no post-operative physical therapy and immediately post-operative physical therapy. All patients were evaluated for delayed return of function, which was defined as use of crutches, lack of > 90 degrees flexion and full extension of the knee, or persistent pain requiring medication at the initial 2-week follow-up visit. Rates of delayed function were compared between the two treatment groups. Results Among the study participants, 48 patients had no physical therapy and 19 patients had immediate post-operative physical therapy. Eighteen patients in the no physical therapy group reported a delay (37.5 %) while only 2 patients in the physical therapy treatment group reported a delay (10.5 %); p = 0.0386. Conclusions Delayed return of function dramatically affects pediatric patients, causing unnecessary absence from school and strain on the caregiver. Therefore, it is important to identify treatment modalities to help mitigate the complications of surgery. We conclude that the use of immediate post-operative physical therapy statistically significantly helps patients to return more rapidly to their functional level. AN - WOS:000215436100010 AU - Fillingham, Y. A. AU - Luthringer, T. AU - Erickson, B. J. AU - Kogan, M. DA - Dec DO - 10.1007/s11832-015-0700-x IS - 6 N1 - Fillingham, Yale A. Luthringer, Tyler Erickson, Brandon J. Kogan, Monica 1863-2548 PY - 2015 SN - 1863-2521 SP - 483-487 ST - Does physical therapy prevent post-operative delay in return of function following tension-band plating? T2 - Journal of Childrens Orthopaedics TI - Does physical therapy prevent post-operative delay in return of function following tension-band plating? UR - ://WOS:000215436100010 VL - 9 ID - 2205 ER - TY - JOUR AB - Background: It is speculated that attending Steiner schools, whose pedagogical principles include an account for healthy psycho-physical development, may have long-term beneficial health effects. We examined whether the current health status differed between former attendees of German Steiner schools and adults from the general population. Furthermore, we examined factors that might explain those differences. Methods: We included former Steiner school attendees from 4 schools in Berlin, Hanover, Nuremberg and Stuttgart and randomly selected population controls. Using a self-report questionnaire we assessed sociodemographics, current and childhood lifestyle and health status. Outcomes were self-reports on 16 diseases: atopic dermatitis, allergic rhinitis, bronchial asthma, chronic obstructive pulmonary disease (COPD), cardiac arrhythmia, cardiac insufficiency, angina pectoris, arteriosclerosis, hypertension, hypercholesterolemia, osteoarthritis, rheumatism, cancer, diabetes, depression and multiple sclerosis. Furthermore, participants rated the symptom burden resulting from back pain, cold symptoms, headache, insomnia, joint pain, gastrointestinal symptoms and imbalance. Unadjusted and adjusted odds ratios were calculated for each outcome. Results: 1136 Steiner school attendees and 1746 controls were eligible for analysis. Both groups were comparable regarding sex, age and region, but differed in nationality and educational status. After adjusting for possible confounders, we found statistically significant effects of Steiner school attendance for osteoarthritis (OR 0.69 [0.49-0.97]) and allergic rhinitis (OR 0.77, [0.59-1.00]) as well as for symptom burden from back pain (OR 0.80, [0.64-1.00]), insomnia (OR 0.65, [0.50-0.84]), joint pain (OR 0.62, [0.48-0.82]), gastrointestinal symptoms (OR 0.76, [0.58-1.00]) and imbalance (OR 0.60, [0.38-0.93]). Conclusions: The risk of most examined diseases did not differ between former Steiner school attendees and the general population after adjustment for sociodemographics, current and childhood lifestyle features, but symptom burden from some current health complaints was reported less by former Steiner school attendees. Results must be interpreted with caution since the analysis was exploratory. AN - WOS:000326240100031 AU - Fischer, H. F. AU - Binting, S. AU - Bockelbrink, A. AU - Heusser, P. AU - Hueck, C. AU - Keil, T. AU - Roll, S. AU - Witt, C. C7 - e73135 DA - Sep DO - 10.1371/journal.pone.0073135 IS - 9 N1 - Fischer, H. Felix Binting, Sylvia Bockelbrink, Angelina Heusser, Peter Hueck, Christoph Keil, Thomas Roll, Stephanie Witt, Claudia Fischer, Felix/AAF-2612-2020 Binting, Sylvia/0000-0003-4241-0924; Witt, Prof. Dr. med., Claudia M./0000-0002-5440-7805; Fischer, Felix/0000-0002-9693-6676; Roll, Stephanie/0000-0003-1191-3289 PY - 2013 SN - 1932-6203 ST - The Effect of Attending Steiner Schools during Childhood on Health in Adulthood: A Multicentre Cross-Sectional Study T2 - Plos One TI - The Effect of Attending Steiner Schools during Childhood on Health in Adulthood: A Multicentre Cross-Sectional Study UR - ://WOS:000326240100031 VL - 8 ID - 2350 ER - TY - JOUR AB - OBJECTIVE: We previously determined that "intent" to return to work post pain facility treatment is the strongest predictor for actual return to work. The purposes of the present study were the following: to identify variables predicting "intent"; to predict membership in the "discrepant with intent" group [those chronic pain patients (CPPs) who do intend to return to work but do not]; and to predict membership in the "discrepant with nonintent" group (those CPPs who do not intend to return to work but do). DESIGN: A total of 128 CPPs completed a series of rating scales and yes/no questions relating to their preinjury job perceptions and a question relating to "intent" to return to the same type of preinjury job post-pain facility treatment. These CPPs were part of a grant study for prediction of return to work, and therefore their work status was determined at 1, 3, 6, 12, 18, 24, and 30 months posttreatment. Preinjury job perceptions and other demographic variables were utilized using stepwise discriminant analysis to identify variables predicting "intent" and predicting membership in the "discrepant with intent" and "discrepant with nonintent" groups. SETTING: Pain facility (multidisciplinary pain center). PATIENTS: Consecutive low back pain CPPs, mean age 41.66+/-9.54 years, with the most frequent highest educational status being high school completion (54.7%) and 60.2% being worker compensation CPPs. RESULTS: "Intent" was predicted by (in decreasing order of probability) postinjury job availability variables, job characteristic variables, and a litigation variable. "Discrepant with intent" was predicted by (in decreasing order of probability) for the 1-month follow-up time point, postinjury job availability variables, pain variables, a litigation variable, and a function perception variable, and for the final follow-up time point, pain variables only. "Discrepant with nonintent" was predicted by (in order of decreasing probability) for the 1-month follow-up time point, a job availability variable, a demographic variable, and a functional perception variable, and for the final follow-up time point a pain variable and a job availability variable. The percentage of CPPs correctly classified by each of these analyses was as follows: "intent" 81.25%, "discrepant with intent" 87.01% (at 1-month follow-up) and 74.03% (final follow-up), "discrepant with nonintent" 92.16% (at 1-month follow-up) and 75.00% (final follow-up). CONCLUSIONS: CPPs intentions of returning to their preinjury jobs are mainly determined by job availability and job characteristic variables but surprisingly not by pain variables. However, the results with "discrepant with intent" and "discrepant with nonintent" groups indicate that actual return to work is determined by an interaction between job availability variables and pain variables with pain variables predominating for long-term outcome. AD - Department of Psychiatry, University of Miami School of Medicine and Comprehensive Pain and Rehabilitation Center at South Shore Hospital, Florida 33139, USA. AN - 10382929 AU - Fishbain, D. A. AU - Cutler, R. B. AU - Rosomoff, H. L. AU - Khalil, T. AU - Steele-Rosomoff, R. DA - Jun DO - 10.1097/00002508-199906000-00012 DP - NLM ET - 1999/06/26 IS - 2 KW - Adult Chronic Disease Disability Evaluation Discriminant Analysis Employment/statistics & numerical data Female Humans Low Back Pain/*rehabilitation Male Middle Aged *Pain Clinics Predictive Value of Tests LA - eng N1 - Fishbain, D A Cutler, R B Rosomoff, H L Khalil, T Steele-Rosomoff, R Journal Article Research Support, U.S. Gov't, Non-P.H.S. United States Clin J Pain. 1999 Jun;15(2):141-50. doi: 10.1097/00002508-199906000-00012. PY - 1999 SN - 0749-8047 (Print) 0749-8047 SP - 141-50 ST - Prediction of "intent", "discrepancy with intent", and "discrepancy with nonintent" for the patient with chronic pain to return to work after treatment at a pain facility T2 - Clin J Pain TI - Prediction of "intent", "discrepancy with intent", and "discrepancy with nonintent" for the patient with chronic pain to return to work after treatment at a pain facility VL - 15 ID - 3431 ER - TY - JOUR AB - Background: Recurrent abdominal pain in children was defined initially by Apley and updated recently by Rome II criteria. The intent of the Rome II criteria is to provide greater insight into functional disorders of the gastrointestinal tract. Because markers for these disorders are lacking, diagnostic evaluations may vary. In this investigation, the individual approach of the primary care physician to the child with functional abdominal pain (as defined by Rome II criteria) is explored both in a hypothetical and clinical setting. Study: A clinical vignette and survey involving the evaluation of a school-aged child with prototypical functional abdominal pain was distributed to area primary care physicians (n = 201 completed). The actual physician approach for functional abdominal pain was determined through chart review of children referred to gastroenterology clinic (n = 103). Results: Physicians favored limited organ-specific testing, with urinalysis, preferred most. Physicians with extreme anticipation of a positive yield requested more testing than their nonanticipatory counterparts (5.7 +/- 2.2 vs. 2.0 +/- 2.0, P < 0.001). Ultrasound was the only diagnostic test requested with greater frequency in actual subjects than hypothetical (31% vs. 18%, P < 0.005). Conclusions: In accordance with published guidelines, physicians requested minimal testing for functional abdominal pain. Increased ultrasound requests in the clinic setting may be more reflective of the need for reassurance rather than seeking an organic etiology. AN - WOS:000239136700007 AU - Fishbein, M. AU - Bernard, B. AU - Ehrlich, C. DA - Jul DO - 10.1097/00004836-200607000-00007 IS - 6 N1 - Fishbein, Mark Bernard, Brad Ehrlich, Christopher 1539-2031 PY - 2006 SN - 0192-0790 SP - 497-503 ST - The primary care physician's approach to functional abdominal pain in childhood T2 - Journal of Clinical Gastroenterology TI - The primary care physician's approach to functional abdominal pain in childhood UR - ://WOS:000239136700007 VL - 40 ID - 2728 ER - TY - JOUR AB - This is a study of the incidence and possible predisposing stress factors of Scheuermann's disease (S.D.). 500, 17 and 18 year old, students from the local larger schools, from one country town school and from the local Teachers' Training College, took part. Each student filled in a questionnaire, underwent a simple spinal examination including a clinical assessment of the available passive hamstring stretch, and had a lateral X-ray of the dorsal and upper lumbar spine. 56.3% of the males and 30.3% of the females had X-ray evidence of previous S.D., in varying degrees of severity. Dynamic stress, such as playing sports involving a lot of potential compression stress, weight lifting, and heavy lifting work in spare time and holidays, seem to play little if any part in the pathogenesis of S.D. Tall males and males who had spent more than 2 weeks in bed, due to sickness or injury, were more prone to S.D. Hamstring tightness showed a significant relationship to X-ray evidence for males. In the absence of possible dynamic stress factors it is suggested that prolonged sitting may be an important factor in the pathogenesis of end plate breakdown and thus S.D. AN - 6230938 AU - Fisk, J. W. AU - Baigent, M. L. AU - Hill, P. D. DA - Feb DP - NLM ET - 1984/02/01 IS - 1 KW - Adolescent Back Pain/etiology Bed Rest Body Height Female Humans Male Physical Examination Radiography Recurrence Scheuermann Disease/diagnosis/*diagnostic imaging/physiopathology Sex Factors Sports Surveys and Questionnaires Tendons/physiopathology LA - eng N1 - Fisk, J W Baigent, M L Hill, P D Journal Article United States Am J Phys Med. 1984 Feb;63(1):18-30. PY - 1984 SN - 0002-9491 (Print) 0002-9491 SP - 18-30 ST - Scheuermann's disease. Clinical and radiological survey of 17 and 18 year olds T2 - Am J Phys Med TI - Scheuermann's disease. Clinical and radiological survey of 17 and 18 year olds VL - 63 ID - 3689 ER - TY - JOUR AB - OBJECTIVE: Although persons with lower socioeconomic status (SES) generally have poorer health status for many medical conditions, the association of SES with symptom severity in fibromyalgia (FM) is unknown. The subjective symptoms of FM may be influenced by personal perceptions, and environmental and psychosocial factors. Therefore SES may influence symptom expression and severity. METHODS: Data for this cross-sectional analysis were obtained from a real-life prospective cohort of 246 patients with FM categorized according to level of education: high school graduates or less (Group 1; n = 99), college graduates (Group 2; n = 84), and university graduates (Group 3; n = 63). The association between level of education, a well-validated measure of SES, and disease severity, functional status, and quality of life were examined. RESULTS: Lower education was significantly associated with older age (p = 0.039), current unemployment (p < 0.001), and more severe disease, as measured by patient global assessment disease activity (p = 0.019), McGill Pain Questionnaire (p = 0.026), Pain Disability Index (p = 0.031), Pain Catastrophizing Scale (p = 0.015), Health Assessment Questionnaire (p = 0.001), and Fibromyalgia Impact Questionnaire (p = 0.002), but not pain level, anxiety, or depression. These associations remained significant even upon adjusting for age and sex differences. CONCLUSION: Patients with FM and lower SES, as assessed by education level, reported greater symptom severity and functional impairment, despite reporting similar levels of pain, depression, and anxiety. Although FM spans all socioeconomic groups, factors other than specific disease characteristics or mental status, appear to play an important role in patients' perception of illness. AD - From the Division of Rheumatology, McGill University Health Centre, Montreal; JSS Medical Research, St-Laurent; Jewish General Hospital, McGill University, Montreal; and Alan Edwards Pain Management Unit, McGill University Health Centre, Montreal, Quebec, Canada.M.A. Fitzcharles, MB, ChB, Division of Rheumatology and Alan Edwards Pain Management Unit, McGill University Health Centre; E. Rampakakis, PhD, JSS Medical Research, and Jewish General Hospital, McGill University; P.A. Ste-Marie, BA, LL.B, Alan Edwards Pain Management Unit, McGill University Health Centre; J.S. Sampalis, PhD, JSS Medical Research, and Jewish General Hospital, McGill University; Y. Shir, MD, Alan Edwards Pain Management Unit, McGill University Health Centre. mary-ann.fitzcharles@muhc.mcgill.ca. From the Division of Rheumatology, McGill University Health Centre, Montreal; JSS Medical Research, St-Laurent; Jewish General Hospital, McGill University, Montreal; and Alan Edwards Pain Management Unit, McGill University Health Centre, Montreal, Quebec, Canada.M.A. Fitzcharles, MB, ChB, Division of Rheumatology and Alan Edwards Pain Management Unit, McGill University Health Centre; E. Rampakakis, PhD, JSS Medical Research, and Jewish General Hospital, McGill University; P.A. Ste-Marie, BA, LL.B, Alan Edwards Pain Management Unit, McGill University Health Centre; J.S. Sampalis, PhD, JSS Medical Research, and Jewish General Hospital, McGill University; Y. Shir, MD, Alan Edwards Pain Management Unit, McGill University Health Centre. AN - 24931954 AU - Fitzcharles, M. A. AU - Rampakakis, E. AU - Ste-Marie, P. A. AU - Sampalis, J. S. AU - Shir, Y. DA - Jul DO - 10.3899/jrheum.131515 DP - NLM ET - 2014/06/17 IS - 7 KW - Adult Cross-Sectional Studies Disability Evaluation Educational Status Female Fibromyalgia/*diagnosis/physiopathology Health Status Humans Male Middle Aged Pain Measurement *Quality of Life Severity of Illness Index *Social Class Socioeconomic Factors Surveys and Questionnaires Fibromyalgia Socioeconomic status LA - eng N1 - Fitzcharles, Mary-Ann Rampakakis, Emmanouil Ste-Marie, Peter A Sampalis, John S Shir, Yoram Journal Article Canada J Rheumatol. 2014 Jul;41(7):1398-404. doi: 10.3899/jrheum.131515. Epub 2014 Jun 15. PY - 2014 SN - 0315-162X (Print) 0315-162x SP - 1398-404 ST - The association of socioeconomic status and symptom severity in persons with fibromyalgia T2 - J Rheumatol TI - The association of socioeconomic status and symptom severity in persons with fibromyalgia VL - 41 ID - 3108 ER - TY - JOUR AB - Nine practitioners who specialize in the treatment of adolescents with chronic pain were interviewed on their perceptions of the adolescents' peer functioning. A qualitative analysis based on Consensual Qualitative Research (CQR) was used. Practitioners generally reported a decline in the adolescents' peer functioning. However, if adolescents had good peer relationships prior to pain onset, they tended to maintain adequate functioning in the social arena while experiencing chronic pain. Practitioners noted that avoidance of peers was a strategy used by adolescents, due more to the pain than social competence issues. They also suggested that adolescents who felt comfortable disclosing pain status, likely to be consistent with good social skills, benefited from peer support. Implications for practice and research are discussed. AN - WOS:000289618400005 AU - Fleischman, K. M. AU - Hains, A. A. AU - Davies, W. H. DA - Mar DO - 10.1177/1367493510395640 IS - 1 N1 - Fleischman, Katie M. Hains, Anthony A. Davies, W. Hobart 1741-2889 PY - 2011 SN - 1367-4935 SP - 50-58 ST - Practitioner perceptions of peer relationships in adolescents with chronic pain T2 - Journal of Child Health Care TI - Practitioner perceptions of peer relationships in adolescents with chronic pain UR - ://WOS:000289618400005 VL - 15 ID - 2506 ER - TY - JOUR AB - The aim of this pilot study was to explore the effects of an early and customized CBT intervention, mainly delivered via internet, for adolescents with coexisting recurrent pain and emotional distress (low mood, worry, and/or distress). The intervention was based on a transdiagnostic approach, to concurrently target pain and emotional distress. A single case experimental design (SCED) was employed with six participants, 17-21 years old, who were recruited via school health care professionals at the student health care team at an upper secondary school in a small town in Sweden. The intervention consisted of 5-9 modules of CBT, delivered via internet in combination with personal contacts and face to face sessions. The content and length of the program was customized depending on needs. The effects of the program were evaluated based on self-report inventories, which the participants filled out before and after the intervention and at a six month follow-up. They did also fill out a diary where they rated symptoms on a daily basis. The results were promising, at least when considering changes during the intervention as well as pre- and posttest ratings. However, the results were more modest when calculating the reliable change index (RCI), and most of the treatment effects were not sustained at the follow-up assessment, which raises questions about the durability of the effects. Taken together, this study indicates that this type of program is promising as an early intervention for adolescents with pain and concurrent emotional distress, although the outcomes need to be explored further, especially in terms of long-term effects. AD - Center for Health and Medical Psychology (CHAMP), Institution of Law, Psychology, and Social Work, Örebro University, Örebro, Sweden. AN - 30135789 AU - Flink, I. K. AU - Sfyrkou, C. AU - Persson, B. C2 - PMC6096266 DA - May DO - 10.1016/j.invent.2016.03.002 DP - NLM ET - 2016/03/26 KW - Adolescents Cbt Emotional distress Pain LA - eng N1 - 2214-7829 Flink, Ida K Sfyrkou, Christina Persson, Bob Journal Article Internet Interv. 2016 Mar 26;4:43-50. doi: 10.1016/j.invent.2016.03.002. eCollection 2016 May. PY - 2016 SN - 2214-7829 SP - 43-50 ST - Customized CBT via internet for adolescents with pain and emotional distress: A pilot study T2 - Internet Interv TI - Customized CBT via internet for adolescents with pain and emotional distress: A pilot study VL - 4 ID - 4196 ER - TY - JOUR AB - P>Background: To date no studies have compared generic health-related quality of life (HRQL) of food allergic patients from childhood to adulthood with that of the general population or patients with other chronic diseases. The aim of this study was to compare generic HRQL of food allergic patients with the general population and other diseases. Methods: Generic HRQL questionnaires (CHQ-CF87 and RAND-36) were completed by 79 children, 74 adolescents and 72 adults with food allergy. The generic HRQL scores were compared with scores from published studies on the general population and patients with asthma, irritable bowel syndrome (IBS), diabetes mellitus (DM) and rheumatoid arthritis (RA). Results: Food allergic children and adolescents reported fewer limitations in school work due to behavioural problems (P < 0.013), but food allergic adolescents and adults reported more pain (P = 0.020), poorer overall health (P < 0.001), more limitations in social activities (P < 0.001) and less vitality (P = 0.002) than individuals from the general population. Food allergic patients reported poorer generic HRQL than patients with DM, but better generic HRQL than patients with RA, asthma and IBS. Conclusion: HRQL is impaired in food allergic adolescents and adults, compared to the general population, and it is intermediate in magnitude between DM and RA, asthma and IBS. Children show the least impact on generic HRQL from food allergy. AN - WOS:000273300600012 AU - Flokstra-de Blok, B. M. J. AU - Dubois, A. E. J. AU - Vlieg-Boerstra, B. J. AU - Elberink, Jngo AU - Raat, H. AU - DunnGalvin, A. AU - Hourihane, J. O. AU - Duiverman, E. J. DA - Feb DO - 10.1111/j.1398-9995.2009.02121.x IS - 2 N1 - Flokstra-de Blok, B. M. J. Dubois, A. E. J. Vlieg-Boerstra, B. J. Elberink, J. N. G. Oude Raat, H. DunnGalvin, A. Hourihane, J. O'B. Duiverman, E. J. DunnGalvin, Audrey/G-1741-2012; Vlieg-Boerstra, Berber/O-1922-2019 Vlieg-Boerstra, Berber/0000-0001-7962-5406 1398-9995 PY - 2010 SN - 0105-4538 SP - 238-244 ST - Health-related quality of life of food allergic patients: comparison with the general population and other diseases T2 - Allergy TI - Health-related quality of life of food allergic patients: comparison with the general population and other diseases UR - ://WOS:000273300600012 VL - 65 ID - 2565 ER - TY - JOUR AB - OBJECTIVE: Eosinophilic esophagitis (EE), a rare chronic inflammatory condition of the esophagus, is predominantly observed in children and is primarily manifested with feeding difficulties. To our knowledge, no self- or caregiver-reported questionnaires are available to assess pediatric EE symptoms and their impact as reported directly by children or their parents/caregivers. The objectives of this study were to characterize the symptoms and impact of EE among children as reported by patients and parents/caregivers and to assess the content validity of two newly developed pediatric eosinophilic esophagitis symptom questionnaires, one parent/caregiver-reported questionnaire for ages 2-7 years and one child-reported questionnaire for ages 8-17 years. The questionnaires were developed based on a review of the literature and clinical expert consultation. RESEARCH DESIGN AND METHODS: This cross-sectional study involving one-on-one interviews with patients and caregivers was conducted at an American Partnership for Eosinophilic Disorders conference. Parents of patients aged 2-7 years (n = 12) and patients aged 8-17 years (n = 16) were first asked about symptoms and their impact on everyday life, using open-ended questions. Participants then completed the appropriate symptom questionnaire and were asked to provide feedback on the relevance, comprehensiveness, and clarity of each item and other questionnaire issues (time to complete, length, format, etc.). All reported symptoms were enumerated, and the feedback on the symptom questionnaires was analyzed qualitatively. RESULTS: The majority of study participants were white (82%) and male (86%). The most frequently reported symptoms of 2-7-year olds were vomiting (92%), "reflux" (50%), dysphagia (25%), abdominal pain (25%), and trouble sleeping (25%). The 8-17-year group reported abdominal pain (56%), vomiting (31%), throat pain (25%), diarrhea (25%), and food getting stuck (25%). Symptoms and treatment were reported to have a major impact on daily life, particularly on school, after-school activities and social events, feeling frustrated regarding symptoms and treatment, and feeling "different". Overall, participants thought that the questionnaires were clear, relevant, and appropriate for symptom assessment. LIMITATION: This study was based on a small and convenient sample of participants attending an EE conference and hence may not be representative of the general EE patient population. CONCLUSIONS: EE is associated with a range of symptoms that vary in terms of the type, frequency and severity across and within patients. The results provide adequate support for the content validity of the self- and caregiver-reported versions of the symptom-specific questionnaires. Minor modifications were made based on the feedback obtained. A psychometric evaluation of the revised questionnaires is needed next to assess the construct validity, reliability, and responsiveness of the measures. AD - Oxford Outcomes Inc, Bethesda, MD 20814, USA. emuella.flood@oxfordoutcomes.com AN - 19032119 AU - Flood, E. M. AU - Beusterien, K. M. AU - Amonkar, M. M. AU - Jurgensen, C. H. AU - Dewit, O. E. AU - Kahl, L. P. AU - Matza, L. S. DA - Dec DO - 10.1185/03007990802536900 DP - NLM ET - 2008/11/27 IS - 12 KW - Abdominal Pain/pathology/physiopathology Adolescent *Caregivers Child Child, Preschool Chronic Disease Cross-Sectional Studies Deglutition Disorders/pathology/physiopathology Diarrhea/pathology/physiopathology Esophagitis/*pathology/*physiopathology Female Gastroesophageal Reflux/pathology/physiopathology Humans Male *Parents Sleep Wake Disorders/pathology/physiopathology *Surveys and Questionnaires Vomiting/pathology/physiopathology LA - eng N1 - 1473-4877 Flood, Emuella M Beusterien, Kathleen M Amonkar, Mayur M Jurgensen, Cynthia H Dewit, Odile E Kahl, Lesley P Matza, Louis S Journal Article Research Support, Non-U.S. Gov't England Curr Med Res Opin. 2008 Dec;24(12):3369-81. doi: 10.1185/03007990802536900. PY - 2008 SN - 0300-7995 SP - 3369-81 ST - Patient and caregiver perspective on pediatric eosinophilic esophagitis and newly developed symptom questionnaires* T2 - Curr Med Res Opin TI - Patient and caregiver perspective on pediatric eosinophilic esophagitis and newly developed symptom questionnaires* VL - 24 ID - 3642 ER - TY - JOUR AB - The aim of the present study is to evaluate the preliminary efficacy of a family intervention with third-wave therapy strategies to promote parental psychological flexibility. Seven mothers aged 31-50 years participated. To assess the effects of the intervention, parental psychological flexibility, avoidance, emotional regulation, parental stress, and satisfaction with life instruments were used at the end of the intervention and at 3 months follow-up. Mood and coping were assessed as the process measure. The effects on their children were assessed with the scale of strengths and difficulties. Intervention comprised four two-hour sessions. Results showed positive effects in the psychological flexibility and emotion regulation of mothers. In children, there was a reduction in emotional symptoms and hyperactivity. This study provides preliminary evidence of the efficacy of third-wave based family interventions. AN - WOS:000525322600003 AU - Flujas-Contreras, J. M. AU - Garcia-Palacios, A. AU - Gomez, I. IS - 1 N1 - Flujas-Contreras, Juan M. Garcia-Palacios, Azucena Gomez, Inmaculada Flujas-Contreras, Juan Miguel/O-1258-2019 Flujas-Contreras, Juan Miguel/0000-0003-0284-1543; Gomez Becerra, Inmaculada/0000-0002-1625-2013 PY - 2020 SN - 1132-9483 SP - 35-57 ST - INTERVENTION IN PARENTAL FLEXIBILITY THROUGH A GROUP INTERVENTION IN FAMILIES T2 - Behavioral Psychology-Psicologia Conductual TI - INTERVENTION IN PARENTAL FLEXIBILITY THROUGH A GROUP INTERVENTION IN FAMILIES UR - ://WOS:000525322600003 VL - 28 ID - 1859 ER - TY - JOUR AB - INTRODUCTION: SCD patients experience declines in health-related quality of life (HRQOL) domains compared with healthy controls. Despite evidence supporting the benefits of hydroxyurea, medication non-adherence remains problematic, especially in adolescents and young adults (AYA). Adherence barriers include forgetfulness and lack of knowledge. Recently, increased interest in technology-based strategies to improve medication adherence has emerged. No data currently exists on hydroxyurea adherence, HRQOL or perceptions of technology-based tools in the Irish SCD population. METHODS: In order to interrogate these domains among Irish AYA SCD patients we administered an anonymous survey at two tertiary referral centres in Dublin, Ireland, in July 2019. RESULTS: Sixty-three patients participated; 63% female and 37% male, with a median and mean age of 17 and 19 years, respectively. Average monthly adherence was 76% using a visual analogue scale. Recall barriers were present in 62% while 26% omit hydroxyurea for reasons other than forgetting. Reviewing HRQOL; only 36.5% felt always physically able to engage in recreational activities, while 51% experienced disruption to school/college/work due to pain. Eighty-one percent reported that anxiety about health interferes with their lives and non-adherence correlated with worse HRQOL outcomes. Interest in a smartphone app was expressed by the majority, with daily medication reminders being the most popular feature. Sharing adherence data with doctors and discussion forums were less appealing. CONCLUSIONS: Representing over 10% of the Irish SCD population, our survey provides novel and valuable insights into medication adherence and HRQOL domains. Preferred app features may inform future technology-based interventions to improve medication adherence in SCD and other chronic health conditions. AD - Irish Centre for Vascular Biology, Royal College of Surgeons in Ireland (RCSI), 123 St Stephen's Green, Dublin, Ireland. fogarthm@tcd.ie. Haematology Department, Children's Health Ireland (CHI) at Crumlin, Dublin, Ireland. fogarthm@tcd.ie. Haematology Department, St James's Hospital, Dublin, Ireland. fogarthm@tcd.ie. Irish Centre for Vascular Biology, Royal College of Surgeons in Ireland (RCSI), 123 St Stephen's Green, Dublin, Ireland. Haematology Department, Children's Health Ireland (CHI) at Crumlin, Dublin, Ireland. Haematology Department, St James's Hospital, Dublin, Ireland. AN - 33745105 AU - Fogarty, H. AU - Gaul, A. AU - Syed, S. AU - Aleksejenko, N. AU - Geoghegan, R. AU - Conroy, H. AU - Crampton, E. AU - Ngwenya, N. AU - Tuohy, E. AU - McMahon, C. DA - Mar 20 DO - 10.1007/s11845-021-02588-1 DP - NLM ET - 2021/03/22 KW - Adolescents and young adults (AYA) Health-related quality of life Hydroxyurea Medication adherence Sickle cell disease Smartphone application LA - eng N1 - 1863-4362 Fogarty, Helen Orcid: 0000-0001-8161-7931 Gaul, Alan Syed, Saifullah Aleksejenko, Natalija Geoghegan, Rosena Conroy, Helena Crampton, Edel Ngwenya, Noel Tuohy, Emma McMahon, Corrina Journal Article Ireland Ir J Med Sci. 2021 Mar 20. doi: 10.1007/s11845-021-02588-1. PY - 2021 SN - 0021-1265 ST - Adherence to hydroxyurea, health-related quality of life domains and attitudes towards a smartphone app among Irish adolescents and young adults with sickle cell disease T2 - Ir J Med Sci TI - Adherence to hydroxyurea, health-related quality of life domains and attitudes towards a smartphone app among Irish adolescents and young adults with sickle cell disease ID - 4151 ER - TY - JOUR AB - BACKGROUND: The purpose of this study was to determine headache characteristics, impact on daily activities and medication attitudes among a large sample of adolescents in Italy. METHODS: Secondary school classes were randomly selected from a national stratified multistage sampling. Data regarding socio-familial factors, headache characteristics, impact on daily activities and medication use were recorded with an anonymous multiple-choice questionnaire. RESULTS: The survey involved 2064 adolescents. 1950 questionnaires were considered for analysis. Study population included 944 males (48.4%) and 1006 females (51.6%), aged between 11 and 16 years (mean 13.5 ± 1.87). Headache prevalence was 65.9%. Mean age at headache onset was 8.33 years. 9.8% suffered from headache > 1/week, 14.3% > 1/month, 24.2% monthly and 17.7% less than monthly. The mean duration of a headache episode was less than 30 min in 32.9%, 1 hour in 28.1%, 2 hours in 19.3% and several hours in 19.5%. Pain intensity was moderate in 52.2% and severe in 9.5%. School represented the main trigger factor (67%). Impact on daily activities was noted in 57.5%. 69.2% of adolescents reported the use of pain relievers. Up to 5.7% declared self-medication, while only 20.6% followed a physician's prescription. Female adolescents experienced headache more frequently (70.2% vs 60%) and more intensely than male peers. Girls had a higher family history of headache, could more frequently identify a trigger factor, and were more affected into their daily activities than boys. CONCLUSIONS: Population-based studies of headache disorders are important, as they inform needs assessment and underpin service policy for a disease that is a public-health priority. Headache has a high prevalence among adolescents and carries a significant burden in terms of impact on daily activities and use of medication. Furthermore, underdiagnose is common, while trigger factors are often detectable. Special consideration should be given to female adolescents and self-medication attitudes. AU - Foiadelli, Thomas AU - Piccorossi, Alessandra AU - Sacchi, Lucia AU - De Amici, Mara AU - Tucci, Maurizio AU - Brambilla, Ilaria AU - Marseglia, Gian Luigi AU - Savasta, Salvatore AU - Verrotti, Alberto DA - 2018/04/04/ DO - 10.1186/s13052-018-0486-9 DP - PubMed IS - 1 J2 - Ital J Pediatr KW - Adolescence Adolescent Analgesics Child Cross-Sectional Studies Female Headache Humans Italian adolescents Italy Male Migraine Migraine Disorders Population-based Prevalence Prognosis Public health Quality of life Questionnaire School Health Services Self Medication Self-medication Severity of Illness Index Surveys and Questionnaires LA - eng PY - 2018 SN - 1824-7288 SP - 44 ST - Clinical characteristics of headache in Italian adolescents aged 11-16 years T2 - Italian Journal of Pediatrics TI - Clinical characteristics of headache in Italian adolescents aged 11-16 years: a cross-sectional questionnaire school-based study UR - http://www.ncbi.nlm.nih.gov/pubmed/29618369 VL - 44 ID - 53 ER - TY - JOUR AB - AIM: To estimate direct and indirect costs in patients with a diagnosis of cluster headache in the US. METHODS: Adult patients (18-64 years of age) enrolled in the Marketscan Commercial and Medicare Databases with ≥2 non-diagnostic outpatient (≥30 days apart between the two outpatient claims) or ≥1 inpatient diagnoses of cluster headache (ICD-9-CM code 339.00, 339.01, or 339.02) between January 1, 2009 and June 30, 2014, were included in the analyses. Patients had ≥6 months of continuous enrollment with medical and pharmacy coverage before and after the index date (first cluster headache diagnosis). Three outcomes were evaluated: (1) healthcare resource utilization, (2) direct healthcare costs, and (3) indirect costs associated with work days lost due to absenteeism and short-term disability. Direct costs included costs of all-cause and cluster headache-related outpatient, inpatient hospitalization, surgery, and pharmacy claims. Indirect costs were based on an average daily wage, which was estimated from the 2014 US Bureau of Labor Statistics and inflated to 2015 dollars. RESULTS: There were 9,328 patients with cluster headache claims included in the analysis. Cluster headache-related total direct costs (mean [standard deviation]) were $3,132 [$13,396] per patient per year (PPPY), accounting for 17.8% of the all-cause total direct cost. Cluster headache-related inpatient hospitalizations ($1,604) and pharmacy ($809) together ($2,413) contributed over 75% of the cluster headache-related direct healthcare cost. There were three sub-groups of patients with claims associated with indirect costs that included absenteeism, short-term disability, and absenteeism + short-term disability. Indirect costs PPPY were $4,928 [$4,860] for absenteeism, $803 [$2,621] for short-term disability, and $3,374 [$3,198] for absenteeism + disability. CONCLUSION: Patients with cluster headache have high healthcare costs that are associated with inpatient admissions and pharmacy fulfillments, and high indirect costs associated with absenteeism and short-term disability. AD - a Eli Lilly and Company , Indianapolis , IN , USA. b Truven Health Analytics, An IBM Company , Ann Arbor , MI , USA. AN - 29125368 AU - Ford, J. H. AU - Nero, D. AU - Kim, G. AU - Chu, B. C. AU - Fowler, R. AU - Ahl, J. AU - Martinez, J. M. DA - Jan DO - 10.1080/13696998.2017.1404470 DP - NLM ET - 2017/11/11 IS - 1 KW - Absenteeism Adolescent Adult Cluster Headache/diagnosis/*drug therapy/*economics/epidemiology *Cost of Illness Databases, Factual Direct Service Costs/statistics & numerical data Drug Costs/statistics & numerical data Female Health Care Costs/*statistics & numerical data Hospitalization/economics/statistics & numerical data Humans Incidence Insurance Claim Review Male Managed Care Programs/economics/statistics & numerical data Middle Aged Severity of Illness Index United States Young Adult Direct and indirect cost analysis claims cluster headache healthcare resource utilization short-term disability LA - eng N1 - 1941-837x Ford, Janet H Nero, Damion Kim, Gilwan Chu, Bong Chul Fowler, Robert Ahl, Jonna Martinez, James M Journal Article England J Med Econ. 2018 Jan;21(1):107-111. doi: 10.1080/13696998.2017.1404470. Epub 2017 Nov 29. PY - 2018 SN - 1369-6998 SP - 107-111 ST - Societal burden of cluster headache in the United States: a descriptive economic analysis T2 - J Med Econ TI - Societal burden of cluster headache in the United States: a descriptive economic analysis VL - 21 ID - 3101 ER - TY - JOUR AB - A systematic review of studies evaluating the effect of psychosocial interventions on social functioning in youth (aged 8-18years) with chronic physical health conditions was conducted. Following the PRISMA guidelines, 13 studies met inclusion criteria. Format and content of interventions and outcome measures varied significantly across studies, precluding meta-analysis. Despite small effect sizes, the findings provide promising support for decreased loneliness and peer problems following intervention, as well as improvements in prosocial behaviors and social acceptance. Many interventions focused largely on communicating about the health condition and were not designed to address a broad range of social difficulties. Targeted interventions to address the unique social challenges of this population may result in improved social functioning. AN - WOS:000436824000006 AU - Forgeron, P. AU - King, S. AU - Reszel, J. AU - Fournier, K. DO - 10.1080/02739615.2017.1328600 IS - 3 N1 - Forgeron, Paula King, Sara Reszel, Jessica Fournier, Karine Forgeron, Paula/0000-0002-4686-9698; Reszel, Jessica/0000-0003-1702-5629 1532-6888 PY - 2018 SN - 0273-9615 SP - 326-355 ST - Psychosocial interventions to improve social functioning of children and adolescents with chronic physical conditions: A systematic review T2 - Childrens Health Care TI - Psychosocial interventions to improve social functioning of children and adolescents with chronic physical conditions: A systematic review UR - ://WOS:000436824000006 VL - 47 ID - 2039 ER - TY - JOUR AB - Aim: To explore the lived experiences of adolescents with sickle cell disease, in Kingston, Jamaica. Method: A descriptive qualitative design was used for this research. In-depth interviews were conducted with six adolescents with sickle cell disease at a Sickle Cell Unit operated by the University of the West Indies. Interviews were audiotaped, transcribed, and thematically analyzed. Results: The majority of the adolescents demonstrated a positive self-concept. They reported strong family, school, and peer support which made them feel accepted. All were actively engaged in social activities such as parties, but had challenges participating in sporting activities. Various coping strategies were utilized to address challenges of the disease including praying, watching television, and surfing the Internet. Conclusion: Sickle cell disease can be very challenging for the adolescent, but with positive self-concept and increased social support, especially from family and peers, these adolescents were able to effectively cope with their condition and live productive lives. AN - WOS:000360577900001 AU - Forrester, A. B. AU - Barton-Gooden, A. AU - Pitter, C. AU - Lindo, J. L. M. C7 - 28104 DO - 10.3402/qhw.v10.28104 N1 - Forrester, Andrea Brown Barton-Gooden, Antoinette Pitter, Cynthia Lindo, Jascinth L. M. Barton-Gooden, Antoinette/AAT-4453-2020 1748-2631 PY - 2015 SN - 1748-2623 ST - The lived experiences of adolescents with sickle cell disease in Kingston, Jamaica T2 - International Journal of Qualitative Studies on Health and Well-Being TI - The lived experiences of adolescents with sickle cell disease in Kingston, Jamaica UR - ://WOS:000360577900001 VL - 10 ID - 2257 ER - TY - JOUR AB - BACKGROUND: Chronic pain among adolescents is common but effective interventions applicable in a school setting are rare. Person-centred care (PCC) is a key factor in improving health by engaging persons as partners in their own care. METHODS: In this randomized controlled trial, a total of 98 adolescents in secondary school or upper secondary school (aged 14 - 21 years) with chronic pain were randomly assigned to a PCC intervention or standard school healthcare. In the intervention group a pain management programme, based on a PCC approach, comprising four face-to-face sessions with a school nurse over a period of 5 weeks was added to standard school healthcare. The main outcome measure was self-efficacy in daily activities (SEDA scale) and rating scales for pain intensity and pain impact were used as secondary outcome measures. RESULTS: At the follow-up, no significant differences were found between the groups in the SEDA scale (p = .608) or in the rating scales for pain intensity (p = .261) and pain impact (p = .836). In the sub-group analysis, a significant improvement in the SEDA scale was detected at the secondary school in favour of the PCC intervention group (p = .021). CONCLUSION: In this pain management programme based on a PCC approach, we found no effect in the total sample, but the programme showed promising results to improve self-efficacy in daily activities among adolescents at secondary school. SIGNIFICANCE: This study evaluates the effects of a pain management programme based on a PCC approach in a school setting addressing adolescents at upper secondary and secondary schools with chronic pain. No overall effects were shown, but results illustrate that the intervention improved self-efficacy in adolescents at secondary school. Implementation of a PCC approach in a school setting may have the potential to improve self-efficacy in daily activities for adolescents with chronic pain at secondary school. AU - Fors, Andreas AU - Wallbing, Ulrika AU - Alfvén, Gösta AU - Kemani, Mike K. AU - Lundberg, Mari AU - Wigert, Helena AU - Nilsson, Stefan DA - 2020/09// DO - 10.1002/ejp.1614 DP - PubMed IS - 8 J2 - Eur J Pain KW - Adolescent Adult Chronic Pain Humans Outcome Assessment, Health Care Schools Self Care Self Efficacy Young Adult LA - eng PY - 2020 SN - 1532-2149 SP - 1598-1608 ST - Effects of a person-centred approach in a school setting for adolescents with chronic pain-The HOPE randomized controlled trial T2 - European Journal of Pain (London, England) TI - Effects of a person-centred approach in a school setting for adolescents with chronic pain-The HOPE randomized controlled trial UR - http://www.ncbi.nlm.nih.gov/pubmed/32501596 VL - 24 ID - 56 ER - TY - JOUR AB - OBJECTIVE: To assess the impact of multiple sclerosis (MS) on the professional life of Brazilian patients. METHOD: One hundred MS patients were randomly selected from the database of the Brazilian Multiple Sclerosis Association (ABEM). An individual interview was carried out by telephone by a member of ABEM, who collected data on the patients' clinical status, educational level and professional lives. RESULTS: Complete data were obtained from 96 patients (27 males and 69 females) aged 55.0±14.1 years, with average disease duration of 4.6±4.0 years). Eighty percent had eleven or more years of schooling. Among the whole group, 66% did not present limitations on walking. The longer the disease duration and the older the patient were, the higher the chances were that the patient was retired or receiving workers' compensation benefits. However, even among patients with MS for less than five years, the rate of non-participation in the workforce was 47.7%. Fatigue, paresthesia, cognitive dysfunction and pain were often cited as the motives for not working. CONCLUSION: MS patients presented high levels of unemployment, retirement and receipt of workers' compensation benefits, despite their high schooling levels. Age, disease duration and disability influenced these results for the whole group. However, even among younger patients with shorter disease duration and low disability, this finding remained. AD - Department of Neurology, Universidade Metropolitana de Santos, SP, Brazil. yara@bsnet.com.br AN - 21243252 AU - Fragoso, Y. D. AU - Finkelsztejn, A. AU - Giacomo, M. C. AU - Russo, L. AU - Cruz, W. S. DA - Dec DO - 10.1590/s0004-282x2010000600016 DP - NLM ET - 2011/01/19 IS - 6 KW - *Absenteeism Adolescent Adult Aged Brazil Chronic Disease Educational Status Female Humans Interviews as Topic Male Middle Aged Multiple Sclerosis/*complications/psychology *Quality of Life Young Adult LA - eng N1 - 1678-4227 Fragoso, Yára Dadalti Finkelsztejn, Alessandro Giacomo, Maria Cristina B Russo, Liliana Cruz, Wesley Soares Journal Article Brazil Arq Neuropsiquiatr. 2010 Dec;68(6):914-7. doi: 10.1590/s0004-282x2010000600016. PY - 2010 SN - 0004-282x SP - 914-7 ST - The effect of multiple sclerosis on the professional life of a group of Brazilian patients T2 - Arq Neuropsiquiatr TI - The effect of multiple sclerosis on the professional life of a group of Brazilian patients VL - 68 ID - 3649 ER - TY - JOUR AB - OBJECTIVE: This paper describes the sociodemographic and health-related characteristics of people with chronic disease attending an interprofessional student-assisted clinic in regional Queensland. DESIGN: A retrospective review of data collected during the first 10 months of operation of the clinic was conducted. SETTING, PARTICIPANTS AND OUTCOME MEASURES: Data was collected on up to 378 patients during an intake appointment at the Capricornia Allied Health Partnership (CAHP) community-based clinic and compared with normative reference groups where available. Sociodemographic characteristics included age, gender and education level; health-related characteristics included body mass index and hospitalisations in the previous 12 months; and risk factors included prescribed medications, smoking status and general practitioner-diagnosed medical conditions. RESULTS: Patients attending the CAHP clinic had a mean number of chronic conditions of 4.9 ± 2.1 per patient, and 97% of patients had multimorbidities. A high level of socioeconomic disadvantage was found in comparison with normative comparison groups based on employment, highest level of schooling completed and the index of social disadvantage. Patients predominantly lived in inner regional areas (76.7%). The most common diagnoses of patients attending the clinic for the first time were hypertension, osteoarthritis, high cholesterol, diabetes and chronic back pain. CONCLUSIONS: The CAHP clinic offers a unique student-assisted service model for interprofessional management of patients who are socioeconomically disadvantaged, have multimorbid chronic disease and live in regional areas. The description of baseline data in this paper is important to refine clinic services, to guide other chronic disease clinics and to inform future research study designs. AD - Central Queensland Hospital and Health Service, Queensland Health, Rockhampton, Australia. kerrieanne_frakes@health.qld.gov.au AN - 23586571 AU - Frakes, K. A. AU - Brownie, S. AU - Davies, L. AU - Thomas, J. AU - Miller, M. E. AU - Tyack, Z. DA - Apr DO - 10.1111/ajr.12017 DP - NLM ET - 2013/04/17 IS - 2 KW - Adolescent Adult Aged Aged, 80 and over Chronic Disease/*epidemiology Female *Health Status Hospitalization/statistics & numerical data Humans Male Middle Aged Prevalence Queensland/epidemiology Retrospective Studies Rural Health Services/organization & administration/statistics & numerical data Rural Population/*statistics & numerical data Students, Medical Young Adult LA - eng N1 - 1440-1584 Frakes, Kerrie-Anne Brownie, Sharon Davies, Lauren Thomas, Janelle Miller, Mary-Ellen Tyack, Zephanie Journal Article Research Support, Non-U.S. Gov't Australia Aust J Rural Health. 2013 Apr;21(2):97-104. doi: 10.1111/ajr.12017. PY - 2013 SN - 1038-5282 SP - 97-104 ST - The sociodemographic and health-related characteristics of a regional population with chronic disease at an interprofessional student-assisted clinic in Queensland Capricornia Allied Health Partnership T2 - Aust J Rural Health TI - The sociodemographic and health-related characteristics of a regional population with chronic disease at an interprofessional student-assisted clinic in Queensland Capricornia Allied Health Partnership VL - 21 ID - 4096 ER - TY - JOUR AB - PURPOSE: Verify the influences of physical activity level, nutritional status and screen habits on the prevalence of back pain in Brazilian students. METHODS: The sample consisted of 577 schoolchildren (female = 274; male = 303) aged between 10 and 16 years old, regularly enrolled in the 6(th) grade of elementary school living in the metropolitan area of the Alto Tietê of the state of São Paulo, Brazil. The prevalence, intensity and frequency of pain was verified with the Back Pain Assessment Instrument. The usual practice of physical activity was verified with the Physical Activity Questionnaire for Older Children/Adolescent. Nutritional status was analyzed using Body Mass Index. Screen habits were obtained through a previously structured questionnaire. RESULTS: The Chi-square test indicated that pain complaint and its prevalence in the cervical region are significantly higher in females (p < 0.05). The multiple logistic regression test revealed that watching television influences the prevalence of cervical pain and that the use of more than one screen increases the occurrence of low back pain in male students (p < 0.05). CONCLUSION: Female students were the most affected by back pain complain, especially in the cervical region. However, factors associated with the prevalence of back pain were found only in males. AD - Núcleo de Pesquisas Tecnológicas (NPT) da Universidade de Mogi das Cruzes (UMC), Mogi das Cruzes, SP, Brazil. Centro Universitário Carlos Drummond de Andrade (UNIDRUMMOND), São Paulo, SP, Brazil. Universidade de São Paulo (USP), São Paulo, SP, Brazil. Centro de Estudos do Laboratório de Aptidão Física de São Caetano do Sul (CELAFISCS), São Caetano, SP, Brazil. Universidade do Vale do Paraíba (UNIVAP), São José dos Campos, SP, Brazil. AN - 32968678 AU - França, E. F. AU - Macedo, M. M. AU - Mafra, F. F. P. AU - Miyake, G. M. AU - da Silva, R. T. AU - de França, T. R. AU - Dos Santos, T. R. AU - Junior, Jpds AU - Matsudo, V. K. R. AU - Junior, N. M. AU - Valentina, E. N. D. AU - Nascimento, F. D. AU - Martins RÁ, B. L. C2 - PMC7505789 DO - 10.3934/publichealth.2020045 DP - NLM ET - 2020/09/25 IS - 3 KW - back pain child obesity childhood physical activity screen habits LA - eng N1 - 2327-8994 França, Erivelton Fernandes Macedo, Michel Monteiro Mafra, Fernando Francisco Pazello Miyake, Gabrielle Mitico da Silva, Romildo Torres de França, Tania Regina Dos Santos, Thyago Ribeiro Junior, João Pedro da Silva Matsudo, Victor Keihan Rodrigues Junior, Nelson Morini Valentina, Eduardo Natali Della Nascimento, Fábio Dupart Martins, Rodrigo Álvaro Brandão Lopes Journal Article AIMS Public Health. 2020 Jul 29;7(3):562-573. doi: 10.3934/publichealth.2020045. eCollection 2020. PY - 2020 SN - 2327-8994 SP - 562-573 ST - Back pain in elementary schoolchildren is related to screen habits T2 - AIMS Public Health TI - Back pain in elementary schoolchildren is related to screen habits VL - 7 ID - 4202 ER - TY - JOUR AB - Background: Back pain is reported to occur already in childhood, but its development at that age is not well understood. The aims of this study were to describe BP in children aged 6-12 years, and to investigate any sex and age differences. Methods: Data on back pain (defined as pain in the neck, mid back and/or lower back) were collected once a week from parents replying to automated text-messages over 2.5 school years from 2008 till 2011. The prevalence estimates were presented as percentages and 95% confidence intervals. Differences between estimates were considered significant if confidence intervals did not overlap. A test for trend, using a multi-level mixed-effects logistic regression extended to the longitudinal and multilevel setting, was performed to see whether back pain reporting increased with age. Results: Depending on the age group, 13-38% children reported back pain at least once per survey year, and 5-23% at least twice per survey year. The average weekly prevalence estimate ranged between 1% and 5%. In the final survey year more girls than boys reported back pain at least twice. The prevalence estimates did not increase monotonically with age but showed a greater increase in children younger than 9/10, after which they remained relatively stable up to the age of 12 years. Conclusions: We found that back pain was not a common problem in this age group and recommend health professionals be vigilant if a child presents with constant or recurring back pain. Our results need to be supplemented by a better understanding of the severity and consequences of back pain in childhood. It would be productive to study the circumstances surrounding the appearance of back pain in childhood, as well as, how various bio-psycho-social factors affect its onset and later recurrence. Knowledge about the causes of back pain in childhood might allow early prevention. AN - WOS:000210328700001 AU - Franz, C. AU - Wedderkopp, N. AU - Jespersen, E. AU - Rexen, C. T. AU - Leboeuf-Yde, C. C7 - 35 DA - Nov DO - 10.1186/s12998-014-0035-6 N1 - Franz, Claudia Wedderkopp, Niels Jespersen, Eva Rexen, Christina Leboeuf-Yde, Charlotte Wedderkopp, Niels/L-9810-2019 Jespersen, Eva/0000-0002-8942-4816; Rexen, Christina Trifonov/0000-0003-0301-9922; Wedderkopp, Niels/0000-0002-9660-6618 PY - 2014 SN - 2045-709X ST - Back pain in children surveyed with weekly text messages - a 2.5 year prospective school cohort study T2 - Chiropractic & Manual Therapies TI - Back pain in children surveyed with weekly text messages - a 2.5 year prospective school cohort study UR - ://WOS:000210328700001 VL - 22 ID - 2277 ER - TY - JOUR AB - Aim of the Study: Pain in children and adolescents in Germany is a common health problem which has a high socioeconomic impact. There have been no studies allowing a reliable estimation of the prevalence of pain in children in the 5(th) grade (age range 9-13 years) in schools in the region of the city of Greifswald and the administrative district East Pomerania. This population-based cross-sectional study examined the prevalence of pain in children, the treatment of pain and compared these data with the results of the German Health Interview and Examination Survey for Children and Adolescents (KiGGS). Methods: Data were collected within the extended dental school examination in autumn 2007 including a self-completion questionnaire for the students. Also the parents answered a self-completion questionnaire containing questions on their children's socio-economic status. The pain and sociodemographic questions are compatible with those used in the "German Health Survey for Children and Adolescents" (KiGGS). Results: Students from 19 schools completed a questionnaire on general pain (n = 852, proportion of response: 93.2%, mean age: 10 years). Comparing to the KiGGS [2] the overall 3-month prevalence is much higher (95.5%). For boys and girls headache is the pain associated with the most burden ("Hauptschmerz"). 1/4 of the girls (27.9%) and 1/5 (22.4%) of the boys reported their pain with the most burden during the last 3 months with a frequency of at least one time per week. Students with low socio-economic status took medication against pain ("Hauptschmerz") less frequently than students with high socioeconomic status. Because of their pain ("Hauptschmerz") students with low socio-economic status visited a doctor less often than students with a mean or high socio-economic status. Conclusion: Compared to other epidemiological studies, pain is also a common health problem for children in the city of Greifswald and the administrative district East Pomerania. The data base enables comprehensive conclusions on the health-related state of students in Greifswald/East Pomerania. Further studies should examine additional factors on medication and the degree of doctor's visits, e.g., parental attitudes towards medication and parental motivation towards the degree of visiting a doctor. AN - WOS:000282496300002 AU - Franze, M. AU - Fendrich, K. AU - Schmidt, C. O. AU - Splieth, C. AU - Hoffmann, W. DA - Sep DO - 10.1055/s-0029-1242785 IS - 8-9 N1 - Franze, M. Fendrich, K. Schmidt, C. O. Splieth, C. Hoffmann, W. Schmidt, Carsten Oliver/AAH-2778-2019 Franze, Marco/0000-0002-2788-6927 1439-4421 PY - 2010 SN - 0941-3790 SP - E45-E50 ST - Pain and Pain Management for Children in Greifswald and East Pomerania: Comparison with the Results of the German Health Interview and Examination Survey for Children and Adolescents (KiGGS) T2 - Gesundheitswesen TI - Pain and Pain Management for Children in Greifswald and East Pomerania: Comparison with the Results of the German Health Interview and Examination Survey for Children and Adolescents (KiGGS) UR - ://WOS:000282496300002 VL - 72 ID - 2538 ER - TY - BOOK A2 - Dalonso, S. A2 - Grasso, K. L. AB - Children and adolescents with Sickle Cell Disease [SCD] frequently experience pain, limiting normal activities such as school attendance, work or play. Most pain episodes are managed at home; although, many children require hospitalization. The episodic and unpredictable nature of SCD-related pain requires patient and caregiver recognition of impending pain and implementation of patient specific treatment to relieve and abate symptoms. Pediatric asthma action plans are standard in the management of chronic asthma care, having been included in both national and international standards for pediatric asthma management for more than a decade. The use of Asthma Action Plans in childhood asthma has improved the outpatient management of symptoms and exacerbations while also reducing the frequency of emergency department visits and hospitalizations. Despite the recognized utility of treatment action plans in chronic disease, no systematic action plan has been developed for the treatment of SCD-related pain. We developed a SCD-specific pain action plan [PAP] to promote patient and caregiver education and self-management strategies that are required for successful ongoing treatment. Every child with SCD is required to have a PAP developed, reviewed and revised at each hematology visit. A PAP is implemented in children as young as six months of age before symptoms appeared. In this commentary, we introduce the theoretical basis for to Support a patient SCD PAP and describe the benefit and barriers associated with developing and implementing a PAP for children with SCD in a single center. We also identify opportunities for future research to assess the clinical utility of a PAP in SCD. AN - WOS:000271188300011 AU - Frei-Jones, M. J. AU - DeBaun, M. R. N1 - Frei-Jones, Melissa J. DeBaun, Michael R. PY - 2009 SN - 978-1-60741-223-6 SP - 213-220 ST - Personal Pain Action Plans for Children and Adolescents with Sickle Cell Disease T2 - Acute Pain: Causes, Effects and Treatment TI - Personal Pain Action Plans for Children and Adolescents with Sickle Cell Disease UR - ://WOS:000271188300011 ID - 2619 ER - TY - JOUR AB - Objective To analyse trends in dental pain prevalence among Brazilian adolescent students over 6 years, focusing on inequalities by maternal education. Methods Data from the National Adolescent School-Based Health Survey (PeNSE) carried out in 2009 (n = 45 239), 2012 (n = 46 482) and 2015 (n = 35 592) were analysed, including ninth grade students from the 27 state capitals in Brazil who were of ages 11-17 years or older. Variables analysed were dental pain within the last 6 months (yes/no) and the following sociodemographic factors: age, sex, race, type of school and maternal schooling (years of study: <= 8; 9-11; >= 12). The prevalence of dental pain in the 3 years was compared using the Rao-Scott test. Relative and absolute measures of socioeconomic (maternal education) inequalities in dental pain were applied using the slope index of inequality (SII) and the relative concentration index (RCI). Results The prevalence of dental pain increased from 17.5% (95% CI = 16.9-18.2) in 2009 to 20.4% (95% CI = 19.7-21.1) in 2012, then to 21.8% (95% CI = 21.1-22.5) in 2015. All sociodemographic factors investigated were associated with dental pain in all survey years. There was an increasing proportion of the outcome in all categories of maternal education over the years studied. Absolute (SII) and relative (RCI) inequalities regarding of maternal education were found; these indicate higher levels of dental pain in the lower socioeconomic group in each study year. However, no significant changes in inequalities were found from 2009 to 2015. Conclusions The prevalence of dental pain increased in the 2009-2012 and 2012-2015 periods, and social inequalities were found. Higher levels of dental pain persisted in the lower maternal education group. Inequalities remained stable over time. Broader actions to reduce the existing inequalities are needed and should be a priority for public policies. AN - WOS:000474064200001 AU - Freire, M. C. M. AU - Jordao, L. M. R. AU - Peres, M. A. AU - Abreu, Mhng DA - Dec DO - 10.1111/cdoe.12483 IS - 6 N1 - Freire, Maria C. M. Jordao, Lidia M. R. Peres, Marco A. Abreu, Mauro H. N. G. Freire, Maria do Carmo Matias/AAF-9890-2021; Abreu, Mauro Henrique/G-6502-2012; Jordao, Lidia M. R./N-7281-2014; Peres, Marco Aurelio/D-1623-2013 Freire, Maria do Carmo Matias/0000-0001-6078-6728; Abreu, Mauro Henrique/0000-0001-8794-5725; Jordao, Lidia M. R./0000-0001-7230-9398; Peres, Marco Aurelio/0000-0002-8329-2808 1600-0528 PY - 2019 SN - 0301-5661 SP - 454-460 ST - Six-year trends in dental pain and maternal education inequalities among Brazilian adolescents T2 - Community Dentistry and Oral Epidemiology TI - Six-year trends in dental pain and maternal education inequalities among Brazilian adolescents UR - ://WOS:000474064200001 VL - 47 ID - 1903 ER - TY - JOUR AB - Primary pain disorders (formerly "functional pain syndromes") are common, under-diagnosed and under-treated in children and teenagers. This manuscript reviews key aspects which support understanding the development of pediatric chronic pain, points to the current pediatric chronic pain terminology, addresses effective treatment strategies, and discusses the evidence-based use of pharmacology. Common symptoms of an underlying pain vulnerability present in the three most common chronic pain disorders in pediatrics: primary headaches, centrally mediated abdominal pain syndromes, and/ or chronic/ recurrent musculoskeletal and joint pain. A significant number of children with repeated acute nociceptive pain episodes develop chronic pain in addition to or as a result of their underlying medical condition "chronic-on-acute pain." We provide description of the structure and process of our interdisciplinary, rehabilitative pain clinic in Minneapolis, Minnesota, USA with accompanying data in the treatment of chronic pain symptoms that persist beyond the expected time of healing. An interdisciplinary approach combining (1) rehabilitation; (2) integrative medicine/active mind-body techniques; (3) psychology; and (4) normalizing daily school attendance, sports, social life and sleep will be presented. As a result of restored function, pain improves and commonly resolves. Opioids are not indicated for primary pain disorders, and other medications, with few exceptions, are usually not first-line therapy. AN - WOS:000392495800007 AU - Friedrichsdorf, S. J. AU - Giordano, J. AU - Dakoji, K. D. AU - Warmuth, A. AU - Daughtry, C. AU - Schulz, C. A. C7 - 42 DA - Dec DO - 10.3390/children3040042 IS - 4 N1 - Friedrichsdorf, Stefan J. Giordano, James Dakoji, Kavita Desai Warmuth, Andrew Daughtry, Cyndee Schulz, Craig A. 2227-9067 PY - 2016 ST - Chronic Pain in Children and Adolescents: Diagnosis and Treatment of Primary Pain Disorders in Head, Abdomen, Muscles and Joints T2 - Children-Basel TI - Chronic Pain in Children and Adolescents: Diagnosis and Treatment of Primary Pain Disorders in Head, Abdomen, Muscles and Joints UR - ://WOS:000392495800007 VL - 3 ID - 2128 ER - TY - JOUR AB - Irritable bowel syndrome (IBS) is a common medical condition with altered bowel habits in association with abdominal pain or discomfort. Recently, the Rome criteria, a classification system of functional gastrointestinal disorders, have been updated; by definition, no mechanical, biochemical, or overt inflammatory condition can explain the patient's symptoms. IBS is one of the most commonly diagnosed gastrointestinal disorders, with a prevalence (estimated from population-based studies) of about 5-15%. IBS accounts for a significant number of visits to primary care physicians and is, after the common cold, the second most common cause of work absenteeism in the United States. The direct and indirect costs of IBS have been estimated to exceed 20 billion U.S. dollars yearly. Aetiology and pathogenesis are unknown, but altered gastrointestinal motility and visceral hypersensitivity might play a role. A few basic investigations are sufficient to rule out organic disease in the absence of alarming symptoms and chronic diarrhoea. Treatment is symptomatic and based on the predominant symptoms of the individual. AN - WOS:000253897300017 AU - Friedt, M. DA - Mar DO - 10.1007/s00112-008-1696-9 IS - 3 N1 - Friedt, M. 1433-0474 PY - 2008 SN - 0026-9298 SP - 275-283 ST - Irritable bowel syndrome T2 - Monatsschrift Kinderheilkunde TI - Irritable bowel syndrome UR - ://WOS:000253897300017 VL - 156 ID - 2662 ER - TY - JOUR AB - Background Frequent complaints of pain (FCP) are common in high-income countries, affecting about 25% of children, and may have significant adverse consequences including prolonged school absence and disability. Most FCP are unexplained, and the aetiology is poorly understood. This study aimed to identify risk factors for FCP and explore how risk factors explain variation in pain reporting by childhood socioeconomic conditions (SECs). Methods Analysis of the UK Millennium Cohort Study, including 8463 singleton children whose parents provided data throughout the study. At 11 years, mothers were asked whether their child frequently complains of pain. Risk ratios (RR) and 95% CIs for FCP were estimated using Poisson regression, according to maternal education. Other risk factors were explored to assess if they attenuated any association between FCP and SECs. Results 32.3% of children frequently complained of pain. Children of mothers with no educational qualifications were more likely to have FCP than children of mothers with higher degrees (RR 2.06, 95% CI 1.64 to 2.59) and there was a clear gradient across the socioeconomic spectrum. Female sex, fruit consumption, childhood mental health and maternal health measures were associated with childhood FCP in univariable and multivariable analyses. Inclusion of these factors within the model attenuated the RR by 17% to 1.70 (95% CI 1.36 to 2.13). Conclusion In this representative UK cohort, there was a significant excess of FCP reported in less advantaged children that was partially attenuated when accounting for indicators of parental and childhood mental health. Addressing these factors may partially reduce inequalities in childhood FCP. AN - WOS:000642294700029 AU - Fryer, B. A. AU - Cleary, G. AU - Wickham, S. L. AU - Barr, B. R. AU - Taylor-Robinson, D. C. C7 - e000093 DA - Aug DO - 10.1136/bmjpo-2017-000093 IS - 1 N1 - Fryer, Benjamin Adam Cleary, Gavin Wickham, Sophie Louise Barr, Benjamin Richard Taylor-Robinson, David Carlton Barr, Ben R/W-9989-2018 Barr, Ben R/0000-0002-4208-9475; Taylor-Robinson, David/0000-0002-5828-7724; Fryer, Benjamin/0000-0001-7636-9785 2399-9772 PY - 2017 ST - Effect of socioeconomic conditions on frequent complaints of pain in children: findings from the UK Millennium Cohort Study T2 - Bmj Paediatrics Open TI - Effect of socioeconomic conditions on frequent complaints of pain in children: findings from the UK Millennium Cohort Study UR - ://WOS:000642294700029 VL - 1 ID - 2082 ER - TY - JOUR AB - This study examined the frequency and severity of sickle related pain, its impact on quality of life, and methods of coping for 25 children with sickle cell disease, aged 6-16 years. Subjects were matched with non-affected peers and asked to complete the Central Middlesex Hospital Children's Health Diary for four weeks. Results indicated that sickle pain occurred on average one in 14 days, and total summary pain scores indicated significantly greater pain than for controls. Children with sickle cell disease could discriminate sickle pain and did not adopt sick role responses to ordinary childhood ailments. Nearly all sickle pain was dealt with at home. Sickle pain resulted in over seven times increased risk of not attending school and was highly disruptive of social and recreational activities. Careful assessment of sickle pain in the home environment is an essential part of a community focused pain management service, which effectively supports children's resilience and improves their quality of life. AN - WOS:A1996VJ60600007 AU - Fuggle, P. AU - Shand, P. A. X. AU - Gill, L. J. AU - Davies, S. C. DA - Sep DO - 10.1136/adc.75.3.199 IS - 3 N1 - Fuggle, P Shand, PAX Gill, LJ Davies, SC PY - 1996 SN - 0003-9888 SP - 199-203 ST - Pain, quality of life, and coping in sickle cell disease T2 - Archives of Disease in Childhood TI - Pain, quality of life, and coping in sickle cell disease UR - ://WOS:A1996VJ60600007 VL - 75 ID - 2921 ER - TY - JOUR AB - BACKGROUND: Musculoskeletal pain is common in childhood and adolescence, and may be long-lasting and recurrent. Musculoskeletal problems tend to follow adolescents into adulthood, and therefore it is important to design better prevention strategies and early effective treatment. To this end, we need in-depth knowledge about the epidemiology of musculoskeletal extremity problems in this age group, and therefore, the aim of this study was to determine the prevalence, frequency and course of musculoskeletal pain in the upper and lower extremities in a cohort of Danish school children aged 8-14 years at baseline. METHODS: This was a prospective 3-year school-based cohort study, with information about musculoskeletal pain collected in two ways. Parents answered weekly mobile phone text messages about the presence or absence of musculoskeletal pain in their children, and a clinical consultation was performed in a subset of the children. RESULTS: We found that approximately half the children had lower extremity pain every study year. This pain lasted on average for 8 weeks out of a study year, and the children had on average two and a half episodes per study year. Approximately one quarter of the children had upper extremity pain every study year that lasted on average 3 weeks during a study year, with one and a half episodes being the average. In general, there were more non-traumatic pain episodes compared with traumatic episodes in the lower extremities, whereas the opposite was true in the upper extremities. The most common anatomical pain sites were 'knee' and 'ankle/ft'. CONCLUSION: Lower extremity pain among children and adolescents is common, recurrent and most often of non-traumatic origin. Upper extremity pain is less common, with fewer and shorter episodes, and usually with a traumatic onset. Girls more frequently reported upper extremity pain, whereas there was no sex-related difference in the lower extremities. The most frequently reported locations were 'knee' and 'ankle/ft'. AU - Fuglkjær, Signe AU - Hartvigsen, Jan AU - Wedderkopp, Niels AU - Boyle, Eleanor AU - Jespersen, Eva AU - Junge, Tina AU - Larsen, Lisbeth Runge AU - Hestbæk, Lise DA - 2017/11/25/ DO - 10.1186/s12891-017-1859-8 DP - PubMed IS - 1 J2 - BMC Musculoskelet Disord KW - Adolescent Adolescent health Arm Child Cohort Complaint Denmark Epidemiology Female Humans Injury Leg Limb Lower Extremity Male Musculoskeletal Pain Pain Measurement Parent-Child Relations Prevalence Prospective Studies Psychomotor Performance Recurrence Schools Time Factors Upper Extremity LA - eng PY - 2017 SN - 1471-2474 SP - 492 ST - Musculoskeletal extremity pain in Danish school children - how often and for how long? T2 - BMC musculoskeletal disorders TI - Musculoskeletal extremity pain in Danish school children - how often and for how long? The CHAMPS study-DK UR - http://www.ncbi.nlm.nih.gov/pubmed/29178864 VL - 18 ID - 73 ER - TY - JOUR AB - We conducted a self-administered questionnaire to investigate ice-cream headache in school adolescents aged 13-15 in Taiwan. The target population was 8789 students in 6 public junior high schools. A total of 8359 students completed the questionnaire (response rate 95.1%). The prevalence of ice-cream headache was 40.6%. It was significantly higher in boys than in girls, and increased with grade. Students with migraine had a higher frequency of ice-cream headache compared with the students without migraine (55.2% vs. 39.6%, P < 0.0001). The prevalence of ice-cream headache increased among students with more migrainous features. Approximately one third of students decreased their intake of ice cream, or abstained completely, especially the younger students. Our study suggests ice-cream headache is very common in Taiwanese adolescents, and it is more common in students who experienced migraine. AD - Neurological Institute, Taipei Veterans General Hospital, National Yang-Ming University School of Medicine [corrected] Taipei, Taiwan. jlfuh@vghtpe.gov.tw AN - 14984231 AU - Fuh, J. L. AU - Wang, S. J. AU - Lu, S. R. AU - Juang, K. D. DA - Dec DO - 10.1046/j.1468-2982.2003.00620.x DP - NLM ET - 2004/02/27 IS - 10 KW - Adolescent Chi-Square Distribution Confidence Intervals Female Headache/*epidemiology *Health Surveys Humans Ice Cream/*adverse effects/statistics & numerical data Male Migraine Disorders/epidemiology Odds Ratio Taiwan/epidemiology LA - eng N1 - Fuh, Jong-Ling Wang, Shuu-Jiun Lu, Shiang-Ru Juang, Kai-Dih Journal Article England Cephalalgia. 2003 Dec;23(10):977-81. doi: 10.1046/j.1468-2982.2003.00620.x. PY - 2003 SN - 0333-1024 (Print) 0333-1024 SP - 977-81 ST - Ice-cream headache--a large survey of 8359 adolescents T2 - Cephalalgia TI - Ice-cream headache--a large survey of 8359 adolescents VL - 23 ID - 3738 ER - TY - JOUR AB - BACKGROUND: Children and adolescents with school phobia sometimes complain of severe and persistent headaches that are diagnosed as chronic daily headache (CDH). METHODS: We investigated 24 children with CDH and school phobia, and 26 children with CDH but without school phobia. RESULTS: Of 24 children with CDH and school phobia, 4% had chronic migraine (CM), 46% had chronic tension-type headache (CTTH) and 50% had both CTTH and migraine. However, of 26 children with CDH but without school phobia, 61% had CM, 24% had CTTH, 11% had CTTH and migraine, and 4% had new daily-persistent headache. There was a significantly higher rate of CTTH and both CTTH and migraine in children with CDH and school phobia than that in children with CDH but without school phobia (P < 0.0001). All of the 24 children with CDH and school phobia were found to have psychiatric disorders. Of 24 children, 71% were found to have adjustment disorders, 21% were found to have anxiety disorders, and 8% were found to have conversion disorder. Of 26 children with CDH but without school phobia, only 20% were found to have psychiatric disorders. There was a significantly higher rate of psychiatric disorders in children with CDH and school phobia than in children with CDH but without school phobia (P < 0.0001). CONCLUSIONS: Our study indicated that children with CDH and school phobia had problems in school and/or family and psychiatric disorders. They should be diagnosed and treated attentively not only for headaches but also for their psychosocial problems and psychiatric disorders. AD - Department of Pediatrics, Tsukuba Gakuen Hospital, Tsukuba, Ibaraki, Japan. mitfujita@tulip.sannet.ne.jp AN - 19438823 AU - Fujita, M. AU - Fujiwara, J. AU - Maki, T. AU - Shibasaki, K. AU - Shigeta, M. AU - Nii, J. DA - Oct DO - 10.1111/j.1442-200X.2009.02804.x DP - NLM ET - 2009/05/15 IS - 5 KW - Adolescent Child Child, Preschool Female Headache Disorders/*complications/diagnosis/therapy Humans Male Phobic Disorders/*complications/diagnosis/therapy Prognosis Retrospective Studies LA - eng N1 - 1442-200x Fujita, Mitsue Fujiwara, Junko Maki, Takako Shibasaki, Kayoko Shigeta, Midori Nii, Junko Journal Article Australia Pediatr Int. 2009 Oct;51(5):621-5. doi: 10.1111/j.1442-200X.2009.02804.x. Epub 2009 Mar 31. PY - 2009 SN - 1328-8067 SP - 621-5 ST - Pediatric chronic daily headache associated with school phobia T2 - Pediatr Int TI - Pediatric chronic daily headache associated with school phobia VL - 51 ID - 3088 ER - TY - JOUR AB - Objective: The aim of the study was to evaluate potential risk factors related to low back pain in the daily routines of two sets of youths: individuals complaining of chronic low back pain and a control group. Methods: The sample consisted of 198 university-age students (male and female) aged between 18 and 29. In accordance with back pain diagnoses, they were separated into two groups: with or without nonspecific chronic low back pain. Both groups were evaluated by a "blinded" observer with no knowledge to the presence or otherwise of lower back pain. Questionnaires concerning clinical-demographic characteristics, life style, quality of life (SF-36 questionnaire), pain visual analogical scales (VAS), and physical examination were applied. Results: A univariate analysis showed a statistically significant association (P < 0.05) with the presence of low back pain and some factors. There was a negative association between low back pain and the following variables: BMI, health self-assessment, VAS and some SF36 domains (physical functioning, body pain, general health, vitality, social functioning). There was a positive correlation with the following variables: global pain by VAS, presence of diffuse pain and number of tender points. However, the multivariate analysis showed statistically significant correlations (P < 0.05) between low back pain and few variables: global pain VAS and number of tender points. Conclusion: Some variables related to chronic diffuse pain and lower quality of life might be associated to chronic low back pain in young adults. However, longitudinal studies are necessary. (C) 2014 Elsevier Editora Ltda. All rights reserved. AN - WOS:000347185600007 AU - Furtado, R. N. V. AU - Ribeiro, L. H. AU - Abdo, B. D. AU - Descio, F. J. AU - Martucci, C. E. AU - Serruya, D. C. DA - Sep-Oct DO - 10.1016/j.rbr.2014.03.018 IS - 5 N1 - Vilar Furtado, Rita Neli Ribeiro, Luiza Helena Abdo, Bruno de Arruda Descio, Fernanda Justo Martucci Junior, Celso Eduardo Serruya, Debora Coutinho PY - 2014 SN - 0482-5004 SP - 371-377 ST - Nonspecific low back pain in young adults: associated risk factors T2 - Revista Brasileira De Reumatologia TI - Nonspecific low back pain in young adults: associated risk factors UR - ://WOS:000347185600007 VL - 54 ID - 2287 ER - TY - JOUR AB - The original Örebro Musculoskeletal Pain Questionnaire (original-ÖMPQ) was developed to identify patients at risk of developing persistent back pain problems and is also advocated for musculoskeletal work injured populations. It is critiqued for its informal non-clinimetric development process and narrow focus. A modified version, the Örebro Musculoskeletal Screening Questionnaire (ÖMSQ), evolved and progressed the original-ÖMPQ to broaden application and improve practicality. This study evaluated and validated the ÖMSQ clinimetric characteristics and predictive ability through a single-stage prospective observational cohort of 143 acute musculoskeletal injured workers from ten Australian physiotherapy clinics. Baseline-ÖMSQ scores were concurrently recorded with functional status and problem severity outcomes, then compared at six months along with absenteeism, costs and recovery time to 80% of pre-injury functional status. The ÖMSQ demonstrated face and content validity with high reliability (ICC(2.1) = 0.978, p < 0.001). The score range was broad (40-174 ÖMSQ-points) with normalised distribution. Factor analysis revealed a six-factor model with internal consistency α = 0.82 (construct range α = 0.26-0.83). Practical characteristics included completion and scoring times (7.5 min), missing responses (5.6%) and Flesch-Kincaid readability (sixth-grade and 70% reading-ease). Predictive ability ÖMSQ-points cut-off scores were: 114 for absenteeism, functional impairment, problem severity and high cost; 83 for no-absenteeism; and 95 for low cost. Baseline-ÖMSQ scores correlated strongly with recovery time to 80% functional status (r = 0.73, p < 0.01). The ÖMSQ was validated prospectively in an acute work-injured musculoskeletal population. The ÖMSQ cut-off scores retain the predictive capacity intent of the original-ÖMPQ and provide clinicians and insurers with identification of patients with potentially high and low risks of unfavourable outcomes. AD - Faculty of Science, Centre for Healthy Activities, Sport and Exercise, University of the Sunshine Coast, Sippy Downs, Sunshine Coast, Queensland 4556, Australia. cp.gabel@bigpond.com AN - 22742989 AU - Gabel, C. P. AU - Melloh, M. AU - Burkett, B. AU - Osborne, J. AU - Yelland, M. DA - Dec DO - 10.1016/j.math.2012.05.014 DP - NLM ET - 2012/06/30 IS - 6 KW - *Absenteeism Adolescent Adult Aged Australia Cohort Studies Disability Evaluation Factor Analysis, Statistical Female Humans Male Mass Screening/*instrumentation Middle Aged Musculoskeletal Diseases/*diagnosis Occupational Injuries/*diagnosis Predictive Value of Tests Primary Health Care/*methods Reproducibility of Results Surveys and Questionnaires/*standards Young Adult LA - eng N1 - 1532-2769 Gabel, Charles Philip Melloh, Markus Burkett, Brendan Osborne, Jason Yelland, Michael Evaluation Study Journal Article Research Support, Non-U.S. Gov't Validation Study Scotland Man Ther. 2012 Dec;17(6):554-65. doi: 10.1016/j.math.2012.05.014. Epub 2012 Jun 27. PY - 2012 SN - 1356-689x SP - 554-65 ST - The Örebro Musculoskeletal Screening Questionnaire: validation of a modified primary care musculoskeletal screening tool in an acute work injured population T2 - Man Ther TI - The Örebro Musculoskeletal Screening Questionnaire: validation of a modified primary care musculoskeletal screening tool in an acute work injured population VL - 17 ID - 3812 ER - TY - JOUR AB - Objective: The study aimed to determine the prevalence of dysmenorrhea in female adolescents living in Tbilisi, Georgia; find possible risk factors and establish an association, if any, with nutrition and sleep hygiene. Material and Methods: A cross-sectional study was used. A retrospective case control study was used to identify risk factors. Participants: A total of 2561 women consented to participate in the research. 431 participants were included in the case-control study. Interventions: Detailed questionnaire included: reproductive history, demographic features, menstrual pattern, severity of dysmenorrhea and associated symptoms; information about nutrition and sleep hygiene. Results: The prevalence of dysmenorrhea was 52.07%. Due to pain, 69.78% reported frequent school absenteeism. The risk of dysmenorrhea in students who had a family history of dysmenorrhea was approximately 6 times higher than in students with no prior history. The prevalence of dysmenorrhea was significantly higher among smokers compared with non-smokers 3.99% vs. 0.68% (p=. 0.05 OR: 6.102). Those women reporting an increased intake of sugar reported a marked increase of dysmenorrhea compared to women reporting no daily sugar intake (55.61% vs. 44.39%, p=. 0023 LR: 0.0002). However, alcohol, family atmosphere and nationality showed no correlation with dysmenorrhea. Our study revealed two most important risk factors of dysmenorrhea: meal skipping 59.78% vs. 27.03%, p=. 00000 LR: 0.00000 OR: 4.014 and sleep hygiene-receiving less sleep 38.77% vs. 19.59%, p=0.000055 LR: 0.000036 OR: 2.598. Conclusion: Primary dysmenorrhea is a common problem in the adolescent population of Tbilisi Geogia. It adversely affects their educational performance. Meal skipping and sleep quantity are associated with dysmenorrhea and may cause other reproductive dysfunctions. AN - WOS:000420652800004 AU - Gagua, T. AU - Tkeshelashvili, B. AU - Gagua, D. DA - Sep DO - 10.5152/jtgga.2012.21 IS - 3 N1 - Gagua, Tinatin Tkeshelashvili, Besarion Gagua, David 1309-0380 PY - 2012 SN - 1309-0399 SP - 162-168 ST - Primary dysmenorrhea: prevalence in adolescent population of Tbilisi, Georgia and risk factors T2 - Journal of the Turkish-German Gynecological Association TI - Primary dysmenorrhea: prevalence in adolescent population of Tbilisi, Georgia and risk factors UR - ://WOS:000420652800004 VL - 13 ID - 2419 ER - TY - JOUR AB - Chronic abdominal pain (CAP) continues to be a diagnostic and therapeutic challenge. It affects about 10% of school-going children and adolescents. Few Indian studies have reported an organic cause in 30%-40% of children with recurrent abdominal pain. In developing countries, parasitic infestations such as giardiasis and ascariasis are an important cause, of recurrent abdominal pain but their frequency has decreased over time. There is a paucity of data from India on the aetiology, epidemiology and management strategies for CAP, and there is no consensus on the clinical approach to this problem. We present a practical approach to CAP in children. The first step is to elicit a detailed history and do a thorough physical examination so as to categorize CAP according to the site of pain (epigastric, periumbilical or left lower quadrant), the predominant symptom associated with pain (dyspepsia, isolated pain or altered bowel habits) and to differentiate the pain as organic or functional based on the characteristics of pain and presence or absence of alarm signs. The second step is to do appropriate investigations, restricted to simple tests when functional pain is suspected (Level I) and more investigations (Level Ia) if there are alarm signs and pain appears to be organic in nature. Invasive investigations such as gastrointestinal endoscopy (Level II) may be reserved for those with possible organic pain. Level III investigations need to be done in a small percentage of children and include EEG, workup for food allergy and porphyria. The third step is management of organic CAP according to the aetiology, while for functional CAP the pharmacological and, rarely, psychological intervention is more difficult but should be done discreetly and tailored to the needs of the child. AD - Department of Paediatrics, Kanchi Kamakoti CHILDS Trust Hospital, Nungambakkam, Chennai, Tamil Nadu. ganeped79@rediffmail.com AN - 20925208 AU - Ganesh, R. AU - Arvind Kumar, R. AU - Suresh, N. AU - Sathiyasekeran, M. DA - Mar-Apr DP - NLM ET - 2010/10/12 IS - 2 KW - Abdominal Pain/*diagnosis/etiology/therapy Child Chronic Disease Humans Physical Examination Prognosis LA - eng N1 - Ganesh, R Arvind Kumar, R Suresh, N Sathiyasekeran, Malathi Journal Article Review India Natl Med J India. 2010 Mar-Apr;23(2):94-9. PY - 2010 SN - 0970-258X (Print) 0970-258x SP - 94-9 ST - Chronic abdominal pain in children T2 - Natl Med J India TI - Chronic abdominal pain in children VL - 23 ID - 3006 ER - TY - JOUR AB - Introduction. Common childhood headaches seldom require prophylactic treatment which, nevertheless, is quite often unsatisfactory. Objective. To study drug and non-drug related factors that may influence the therapeutic response. Material and methods. A four-month follow-up study of all patients attended during a year at the neuropediatric, outpatient hospital-based clinic, with greater than or equal to 2 monthly migraine without aura attacks, greater than or equal to 10 tension-type headaches, or both types of headaches. Patients were randomized to be treated on an open basis, placebo controlled, with flunarizine or piracetam. Headache frequency was evaluated according to treatment and patients' basal characteristics. Results, 98 patients studied (56 migraine without aura, 24 tension-type headache, 18 mixed). 33% dropped out; they were school underachievers more frequently than those that completed the protocol. Of those completing the protocol and treated with placebo as the first choice of therapy, 27% reported total remission of symptomatology; those not remitting with placebo were high achievers at school significatively more frequently. At the end of the trial, 43% of the initially randomized patients still complained of headaches, regardless of treatment, showing a seasonal relationship. Conclusions. Prophylaxis of benign childhood headaches is needed in less than half of those reporting a high headache frequency; school achievement should be taken into consideration as another clue to compliance and headache persistence. On a short-term basis only the seasonal influence and the placebo effect call be held responsible for amelioration of symptomatology. AN - WOS:000073004000006 AU - Garaizar, C. AU - Prats, J. M. AU - Zuazo, E. DA - Mar DO - 10.33588/rn.26151.98955 IS - 151 N1 - Garaizar, C Prats, JM Zuazo, E 1576-6578 PY - 1998 SN - 0210-0010 SP - 380-385 ST - Results of prophylactic treatment for common childhood headaches T2 - Revista De Neurologia TI - Results of prophylactic treatment for common childhood headaches UR - ://WOS:000073004000006 VL - 26 ID - 2900 ER - TY - JOUR AB - Background Functional abdominal pain disorders (FAPD) are common in school-aged children; however, there is no reliable treatment. Aim To determine the efficacy of Lactobacillus rhamnosus GG (LGG) for treating FAPD in children. Methods A total of 104 children who fulfilled the Rome II criteria for functional dyspepsia (FD), or irritable bowel syndrome (IBS), or functional abdominal pain (FAP) were enrolled in a double-blind, randomized controlled trial in which they received LGG (n = 52), or placebo (n = 52) for 4 weeks. Results For the overall study population, those in the LGG group were more likely to have treatment success (no pain) than those in the placebo group (25% vs. 9.6%, relative benefit (RB) 2.6, 95% confidence interval (CI): 1.05-6.6, number needed to treat (NNT) 7, 95% CI: 4-123). For children with IBS (n = 37), those in the LGG group were more likely to have treatment success than those in the placebo group (33% vs. 5%, RB 6.3, 95% CI: 1.2-38, NNT 4, 95% CI: 2-36) and reduced frequency of pain (P = 0.02), but not pain severity (P = 0.10). For the FD group (n = 20) and FAP group (n = 47), no differences were found. Conclusion The LGG appears to moderately increase treatment success, particularly among children with IBS. AN - WOS:000243230300007 AU - Gawronska, A. AU - Dziechciarz, P. AU - Horvath, A. AU - Szajewska, H. DA - Jan DO - 10.1111/j.1365-2036.2006.03175.x IS - 2 N1 - Gawronska, A. Dziechciarz, P. Horvath, A. Szajewska, H. Dziechciarz, Piotr/X-3659-2018; Szajewska, Hania/M-4141-2018; Gawronska, Agnieszka/X-1887-2018; Horvath, Andrea/S-5069-2018 Dziechciarz, Piotr/0000-0003-4227-3130; Szajewska, Hania/0000-0002-4596-2874; Gawronska, Agnieszka/0000-0001-6521-1050; Horvath, Andrea/0000-0001-9940-0001 1365-2036 PY - 2007 SN - 0269-2813 SP - 177-184 ST - A randomized double-blind placebo-controlled trial of Lactobacillus GG for abdominal pain disorders in children T2 - Alimentary Pharmacology & Therapeutics TI - A randomized double-blind placebo-controlled trial of Lactobacillus GG for abdominal pain disorders in children UR - ://WOS:000243230300007 VL - 25 ID - 2703 ER - TY - JOUR AB - Recurrent abdominal pain is a frequent complaint of school-aged children. In 5-10 percent of the cases, RAP is the result of organic disease. Specific history and physical assessments are needed to detect organic disease. The assessment tool described in this article is a functional adjunct to a nurse practitioner's evaluation of RAP as well as of other recurrent pain. It provides additional information to identify less obvious organic causes and serves as a basis for involving the patient in development of a treatment plan. AN - 6633981 AU - Gaylord, N. AU - Carson, S. DA - Sep DP - NLM ET - 1983/09/01 IS - 8 KW - *Abdomen Child Humans Male Medical Records Nurse Practitioners Nursing Assessment/*methods Nursing Process/*methods Pain/*diagnosis Recurrence School Nursing LA - eng N1 - Gaylord, N Carson, S Case Reports Journal Article Research Support, Non-U.S. Gov't United States Nurse Pract. 1983 Sep;8(8):19-24. PY - 1983 SN - 0361-1817 (Print) 0361-1817 SP - 19-24 ST - Assessing recurrent abdominal pain in children T2 - Nurse Pract TI - Assessing recurrent abdominal pain in children VL - 8 ID - 3458 ER - TY - JOUR AB - Jenny Aubry (1903-1987) was the second woman to obtain the title of Physician of the Paris Teaching Hospitals, in 1939. She was a pediatrician and a neurologist. In 1945, she was awarded the Medal of the Resistance for having hidden Jewish children and employees in the Institution for Gifted Children where she was house physician. She also wrote tuberculosis certificates for young Frenchmen to protect them from being sent to Germany to perform compulsory labor, After the war, she began training as a psychoanalyst after she met Anna Freud in 1948. She finished her training with Lacan and remained faithful to his school of thought throughout subsequent controversies. Among her most striking achievements was a system that provided foster homes and psychoanalytical treatment to children whose parents were unable to raise them or had abandoned them. The first teacher to work In a pediatric ward was introduced there by Jenny Aubry. She took pains to make daycare centers for the children of hospital employees more appealing by having them attractively painted, appropriately furnished, and more generously staffed, and she rook similar steps in the pediatric departments that she headed. The enormous effort she put into creating strong ties between pediatrics and psychoanalysis is perhaps the most salient feature of her career. In the last department she headed, at the Enfants-Malades Teaching Hospital in Paris, psychoanalysts and pediatricians worked in close cooperation, and an outpatient psychoanalysis clinic was created. She taught her students and nurses to listen to the children and their parents, repeatedly pointing out the contribution of psychological factors to the emergence of many diseases, and she also persuaded the administration to extend visiting hours to the entire day so that parents could feed their children and put them to bed. Minimizing separation of hospitalized children from their parents was among her key priorities. During her retirement in Aix-en-Provence, she helped to develop psychoanalysis in the South East of France. She wrote articles with her students, suggested topics for doctoral dissertations, made films on abandoned children, and wrote a book on the same topic, which was reedited three times. AN - WOS:A1997WU61300010 AU - Geber, M. DA - Apr IS - 13-14 N1 - Geber, M PY - 1997 SN - 0037-1777 SP - 426-434 ST - Jenny Aubry, Professor at the College of Medicine of the Paris Teaching Hospitals (1903-1987) T2 - Semaine Des Hopitaux TI - Jenny Aubry, Professor at the College of Medicine of the Paris Teaching Hospitals (1903-1987) UR - ://WOS:A1997WU61300010 VL - 73 ID - 2912 ER - TY - JOUR AB - Background: Dermatologists provide the bulk of psychocutaneous care; however, recent studies suggest that dermatologists believe they are largely underprepared to treat most psychocutaneous conditions. Objective: We sought to identify gaps in psychodermatologic knowledge among practicing dermatologists in two academic institutions. Methods: An online survey was sent to 59 dermatologists at the Massachusetts General Hospital (Boston, MA) and Brigham and Women's Hospital (Boston, MA) from July 2010 through October 2011. Results: The response rate was 40 of 59 (68%). More than 50% of dermatologists were comfortable making diagnoses for 8 of 10 psychocutaneous disorders. In all, 57% were comfortable making a diagnosis of depression. A total of 11% were comfortable starting antidepressants; 3%, antipsychotics; and 66%, medications for neuropathic pain. In all, 72%, 68%, and 21% of dermatologists never prescribe antidepressants, antipsychotics, or medications for neuropathic pain, respectively. Only 38% believed they were successful treating compulsive skin picking; 15%, body dysmorphic disorder; 27%, delusions of parasitosis; and 24%, depression. Limitations: Limitations include small sample size, data extraction from an academic setting, self-reporting of outcome measures, and response bias. Conclusion: Although the majority of the physicians surveyed believed they were capable of diagnosing psychocutaneous disease, very few were comfortable starting psychotropics or thought they were successful treating such conditions. (J Am Acad Dermatol 2013;68:47-52.) AN - WOS:000312270900010 AU - Gee, S. N. AU - Zakhary, L. AU - Keuthen, N. AU - Kroshinsky, D. AU - Kimball, A. B. DA - Jan DO - 10.1016/j.jaad.2012.04.007 IS - 1 N1 - Gee, Sarah N. Zakhary, Lisa Keuthen, Nancy Kroshinsky, Daniela Kimball, Alexa Boer Kimball, Alexandra B./M-6347-2019; Kroshinsky, Daniela/AAM-4608-2020 Kroshinsky, Daniela/0000-0002-4781-9676; Kimball, Alexandra/0000-0001-9405-0479 PY - 2013 SN - 0190-9622 SP - 47-52 ST - A survey assessment of the recognition and treatment of psychocutaneous disorders in the outpatient dermatology setting: How prepared are we? T2 - Journal of the American Academy of Dermatology TI - A survey assessment of the recognition and treatment of psychocutaneous disorders in the outpatient dermatology setting: How prepared are we? UR - ://WOS:000312270900010 VL - 68 ID - 2402 ER - TY - JOUR AB - Purpose of reviewPsychiatric comorbidities are sometimes assumed in children with migraine. The goal of this review is to review the evidence for an association between psychiatric comorbidities and pediatric migraine.Recent findingsAlthough depression or anxiety symptom scores may be higher in children with migraine who attend subspecialty clinics, the proportion of children with migraine who have clinically significant depression and anxiety is generally not elevated. In studies of children with migraine in the general population, the anxiety and depression scores are generally not elevated. Some of the scales used to measure anxiety and depression include questions about headaches and/or nausea, which makes them suboptimal tools for use in children with migraine as those are symptoms of migraine. Of note, depression was associated with incident development of chronic migraine in adolescents in one study.SummaryThe majority of children and adolescents with migraine do not have a comorbid psychiatric disorder. When a child with migraine does have a comorbid psychiatric disorder, it should be treated appropriately. AN - WOS:000354067500009 AU - Gelfand, A. A. DA - Jun DO - 10.1097/wco.0000000000000192 IS - 3 N1 - Gelfand, Amy A. Gelfand, Amy/P-9386-2019 1473-6551 PY - 2015 SN - 1350-7540 SP - 261-264 ST - Psychiatric comorbidity and paediatric migraine: examining the evidence T2 - Current Opinion in Neurology TI - Psychiatric comorbidity and paediatric migraine: examining the evidence UR - ://WOS:000354067500009 VL - 28 ID - 2236 ER - TY - JOUR AB - Ethanol is widely known for its ability to cause dramatic changes in emotion, social cognition, and behavior following systemic administration in humans. Human neuroimaging studies suggest that alcohol dependence and chronic pain may share common mechanisms through amygdala-medial prefrontal cortex (mPFC) interactions. However, whether acute administration of ethanol in the mPFC can modulate pain perception is unknown. Here we showed that bilateral microinjections of ethanol into the prelimbic and infralimbic areas of the mPFC lowered the bilateral mechanical pain threshold for 48 h without influencing thermal pain sensitivity in adult rats. However, bilateral microinjections of artificial cerebrospinal fluid into the mPFC or bilateral microinjections of ethanol into the dorsolateral PFC (also termed as motor cortex area 1 in Paxinos and Watson's atlas of The Rat Brain. Elsevier Academic Press, Amsterdam, 2005) failed to do so, suggesting regional selectivity of the effects of ethanol. Moreover, bilateral microinjections of ethanol did not change the expression of either pro-apoptotic (caspase-3 and Bax) or anti-apoptotic (Bcl-2) proteins, suggesting that the dose was safe and validating the method used in the current study. To determine whether gamma-aminobutyric acid A (GABA(A)) receptors are involved in mediating the ethanol effects, muscimol, a selective GABA(A) receptor agonist, or bicuculline, a selective GABA(A) receptor antagonist, was administered alone or co-administered with ethanol through the same route into the bilateral mPFC. The results showed that muscimol mimicked the effects of ethanol while bicuculline completely reversed the effects of ethanol and muscimol. In conclusion, ethanol increases mechanical pain sensitivity through activation of GABA(A) receptors in the mPFC of rats. AN - WOS:000384601700002 AU - Geng, K. W. AU - He, T. AU - Wang, R. R. AU - Li, C. L. AU - Luo, W. J. AU - Wu, F. F. AU - Wang, Y. AU - Li, Z. AU - Lu, Y. F. AU - Guan, S. M. AU - Chen, J. DA - Oct DO - 10.1007/s12264-016-0063-4 IS - 5 N1 - Geng, Kai-Wen He, Ting Wang, Rui-Rui Li, Chun-Li Luo, Wen-Jun Wu, Fang-Fang Wang, Yan Li, Zhen Lu, Yun-Fei Guan, Su-Min Chen, Jun Chen, Jun/R-8412-2017 1995-8218 PY - 2016 SN - 1673-7067 SP - 433-444 ST - Ethanol Increases Mechanical Pain Sensitivity in Rats via Activation of GABA(A) Receptors in Medial Prefrontal Cortex T2 - Neuroscience Bulletin TI - Ethanol Increases Mechanical Pain Sensitivity in Rats via Activation of GABA(A) Receptors in Medial Prefrontal Cortex UR - ://WOS:000384601700002 VL - 32 ID - 2144 ER - TY - JOUR AB - Background Sickle cell disease (SCD) induces chronic haemolytic anaemia and intermittent vaso-occlusion that results in tissue ischaemia causing acute, severe pain episodes that can lead to frequent hospitalizations. These consequences can have repercussions on family, social, school and/or professional life. Here, we present some of the results of the PHEDRE study (Pharmacodependance Et DREpanocytose-drug dependence and sickle-cell disease), which is the largest study of patients with SCD in France. This paper intends to describe characteristics of the French SCD population. We also aimed to assess the impact of the disease on the lives of patients using objective and subjective variables. Methods The PHEDRE study was a national multicentric observational study. Adults, adolescents and children with a confirmed SCD diagnosis were included in the study by their referring doctor. Then, they were interviewed by phone about their socioeconomic status, about the impact of the disease on their lives and about their analgesic and psychoactive drug use. Results The study population consisted of 872 patients (28% were minors). Seventy-two percent of adults were active, and all minors were in school. Many patients presented criteria of severe SCD. Seventy-five percent were homozygous SS, 15% were double heterozygotes SC and 8% were heterozygotes S beta thal, 87% received specific treatment, 58% were hospitalized at least once for vaso-occlusive crisis in the past 12 months, and the number of analgesic drugs taken averaged 3.8. Seventy-five percent of patients reported academic or professional consequences related to their SCD, and 52% reported social consequences. Conclusions The impact of SCD on patients' lives can be significant, nevertheless their social integration seems to be maintained. We highlighted respect of recommendations regarding analgesic treatments and only a few patients used tobacco, alcohol or cannabis. AN - WOS:000631029700079 AU - Gerardin, M. AU - Rousselet, M. AU - Couec, M. L. AU - Masseau, A. AU - Guerlais, M. AU - Authier, N. AU - Deheul, S. AU - Roussin, A. AU - Micallef, J. AU - Djezzar, S. AU - Feuillet, F. AU - Jolliet, P. AU - Victorri-Vigneau, C. AU - Fan C7 - e0248649 DA - Mar DO - 10.1371/journal.pone.0248649 IS - 3 N1 - Gerardin, Marie Rousselet, Morgane Couec, Marie-Laure Masseau, Agathe Guerlais, Marylene Authier, Nicolas Deheul, Sylvie Roussin, Anne Micallef, Joelle Djezzar, Samira Feuillet, Fanny Jolliet, Pascale Victorri-Vigneau, Caroline Rousselet, Morgane/0000-0003-4027-7963 PY - 2021 SN - 1932-6203 ST - Descriptive analysis of sickle cell patients living in France: The PHEDRE cross-sectional study T2 - Plos One TI - Descriptive analysis of sickle cell patients living in France: The PHEDRE cross-sectional study UR - ://WOS:000631029700079 VL - 16 ID - 1747 ER - TY - JOUR AB - Background: Children suffering from chronic headaches experience a significant decrease in quality of life which greatly affects their everyday life. The present study compared the impact of a new multimodal behavioral treatment (MIPAS-Family) to a biofeedback treatment on measures of quality of life for children with chronic headaches. Patients and methods: Thirty-four recurrent headache sufferers, ranging from 7 to 16 years, were randomly assigned to the MIPAS-Family (N = 19) or the biofeedback (N = 15) condition. All patients were diagnosed according to the criteria of the International Headache Society (IHS). The children and their parents completed the following questionnaires prior to and following treatment as well as one year later: the KINDL (R) (which assess quality of life), the Impact of Family Scale, and a German parental questionnaire which assess child behavior. Results: Both groups showed significant improvements in the domains assessed by the KINDL-school, homework, and leisure-time activity. These effects endured for one year after the completion of treatment. Conclusions: MIPAS-Family and biofeedback both lead to significant improvements in quality of life in children experiencing recurrent headaches. AN - WOS:000270787000003 AU - Gerber, W. D. AU - Gerber-von Muller, G. AU - Petermann, U. AU - Niederberger, U. AU - Petermann, F. DO - 10.1026/1616-3443.38.4.231 IS - 4 N1 - Gerber, Wolf-Dieter Gerber-von Mueller, Gabriele Petermann, Ulrike Niederberger, Uwe Petermann, Franz Niederberger, Uwe/A-8256-2010; Gerber, Wolf-Dieter/A-8249-2010 Niederberger, Uwe/0000-0003-3099-0183; 2190-6297 PY - 2009 SN - 1616-3443 SP - 231-239 ST - Do behavioral medicine approaches have an effect on the quality of life and everyday competence of children suffering from chronic headaches? T2 - Zeitschrift Fur Klinische Psychologie Und Psychotherapie TI - Do behavioral medicine approaches have an effect on the quality of life and everyday competence of children suffering from chronic headaches? UR - ://WOS:000270787000003 VL - 38 ID - 2629 ER - TY - JOUR AB - Several meta-analyses have demonstrated that the combination of electrical muscle activity and Temperature Biofeedback could be regarded as gold standard in chronic pediatric headaches. However, these techniques seem to be uneconomical and furthermore they are not directed to improve the social competence as well as resolve possible impairments in daily activities of the child. Therefore, multi-modal behavioral techniques have been proposed, but no studies comparing these with the gold standard were conducted. The present study compared the impact of a new multi-modal behavioral education and training program-MIPAS-Family-with a combined Biofeedback treatment, evaluating clinical efficacy as well as the effect on the quality of life (QoL) of children with chronic headaches. Thirty-four children and adolescents with recurrent headache, ranging from 7 to 16 years, were randomly assigned to the MIPAS-Family (N = 19) or the Biofeedback (N = 15) condition. All patients were diagnosed by the criteria of the International Headache Society. The children and their parents completed headache diaries, diaries of daily living activities and a QoL questionnaire (KINDLA (R)). Both groups showed significant improvements concerning the headache intensity and headache duration. We found no significant differences in the main headache parameters between both treatments. After the treatments, the children were less disturbed by their headaches in the domains school, homework, and leisure time. In conclusion, MIPAS-Family is as effective as Biofeedback but it is more cost-effective and addresses the whole family and the daily activities. AN - WOS:000277450200005 AU - Gerber, W. D. AU - Petermann, F. AU - Gerber-von Muller, G. AU - Dollwet, M. AU - Darabaneanu, S. AU - Niederberger, U. AU - Schulte, I. E. AU - Stephani, U. AU - Andrasik, F. DA - Jun DO - 10.1007/s10194-010-0192-5 IS - 3 N1 - Gerber, Wolf-Dieter Petermann, Franz Gerber-von Mueller, Gabriele Dollwet, Maren Darabaneanu, Stephanie Niederberger, Uwe Schulte, Ilva Elena Stephani, Ulrich Andrasik, Frank Niederberger, Uwe/A-8256-2010; Stephani, Ulrich/D-1004-2010; Gerber, Wolf-Dieter/A-8249-2010 Niederberger, Uwe/0000-0003-3099-0183; Andrasik, Frank/0000-0001-6625-479X 1129-2377 PY - 2010 SN - 1129-2369 SP - 215-225 ST - MIPAS-Family-evaluation of a new multi-modal behavioral training program for pediatric headaches: clinical effects and the impact on quality of life T2 - Journal of Headache and Pain TI - MIPAS-Family-evaluation of a new multi-modal behavioral training program for pediatric headaches: clinical effects and the impact on quality of life UR - ://WOS:000277450200005 VL - 11 ID - 2550 ER - TY - JOUR AB - OBJECTIVE: The origin of a differentiated approach to neuropsychopharmacotherapy in children and adolescents can be traced back to the 1940s and 50s. Certain clinical disorders in the range of psychiatry and neurology were treated with a multiplicity of substances. METHOD: We conducted an exclusive screening of 700 medical records of patients under 18 years of age from a psychiatric university hospital in Jena (from 1942–1945) and 89 files of children who attended Trüper’s approved school in Jena between 1946 and 1954. RESULTS: Differentiated therapies were administered for ailments such as acute anxiety states, erethism, hyperkinetic syndrome, enuresis, migraine, sleep disturbance, epilepsy, Sydenham’s chorea, spasticity, neuralgia, neuritis, dizziness, pain syndrome, tetany, and syphilis. CONCLUSIONS: Interventions for mental disorders were relatively unspecific before the development of neuroleptic and antidepressant agents. During this time, multitudes of treatments were implemented for neurovegetative disorders, psychoneuroses, and different kinds of psychopathies. Barbiturates were administered in both pure and mixed forms. Additionally, since mental disorders were frequently caused by physical disorders, they could be eliminated or improved by the use of chemotherapeutics. Other somatic therapies like convulsive shock treatment with camphor and cardiazol, malaria treatments, hypoglycemic shock therapy, and electroconvulsive treatment have been applied in patients with schizophrenia. AD - 1 Klinik für Kinder- und Jugendpsychiatrie, -psychosomatik und -psychotherapie I, Salus-Fachklinikum Bernburg. 2 Klinik für Kinder- und Jugendpsychiatrie, Psychotherapie und Psychosomatik, Universitätsklinikum Jena. AN - 27058833 AU - Gerhard, U. J. AU - Schönberg, A. DO - 10.1024/1422-4917/a000414 DP - NLM ET - 2016/04/09 IS - 4 KW - Adolescent Adolescent Psychiatry/*history Central Nervous System Agents/*history Child Child Psychiatry/*history Germany History, 20th Century Humans Psychopharmacology/*history Psychotropic Drugs/*history *child and adolescent psychiatry *origin of neuropsychopharmacotherapy *convulsive shock treatment *psychiatric university hospital in Jena *Trüper’s approved school LA - ger N1 - Gerhard, Uwe-Jens Schönberg, Anke English Abstract Historical Article Journal Article Switzerland Z Kinder Jugendpsychiatr Psychother. 2016;44(4):285-94. doi: 10.1024/1422-4917/a000414. Epub 2016 Apr 8. OP - Die Anfänge einer differenzierten Neuropsychopharmakotherapie bei Kindern und Jugendlichen. Untersuchung zur Psycho- und Neuropharmakologie in den 40er und 50er Jahren des vorigen Jahrhunderts. PY - 2016 SN - 1422-4917 (Print) 1422-4917 SP - 285-94 ST - [The origin of a differentiated neuropsychopharmacotherapy for children and adolescents: an analysis of psycho- and neuropharmacology in the 1940s and 50s] T2 - Z Kinder Jugendpsychiatr Psychother TI - [The origin of a differentiated neuropsychopharmacotherapy for children and adolescents: an analysis of psycho- and neuropharmacology in the 1940s and 50s] VL - 44 ID - 3856 ER - TY - JOUR AB - Background: Pediatric acupuncture within academic health centers is an expanding service, with more than one third of pediatric pain centers in the United States offering acupuncture-related modalities. Despite consumer demand for acupuncture, there is little information in the literature regarding the "how-to'' of building these programs. Methods: This article summarizes two models of incorporating pediatric acupuncture in academic health centers and describes methods of application of pediatric acupuncture within an academic health environment. Results: A comparison of these models and a blueprint for the development and success of acupuncture services within pediatric health centers are presented. Conclusions: Pediatric acupuncture can be a vital addition to holistic integrative care for children in an academic center, but it requires collaborative implementation, particularly in the areas of clinical service, education, research, and reimbursement strategies. Long- term viability of pediatric acupuncture within an academic pediatric setting is aided by joint administrative support from both hospital and medical school, as well as measures of performance outcome and patient satisfaction. AN - WOS:000217806700008 AU - Gershan, L. A. DA - Dec DO - 10.1089/acu.2015.1143 IS - 6 N1 - Gershan, Lynn A. 1933-6594 Si PY - 2015 SN - 1933-6586 SP - 442-446 ST - Acupuncture in Pediatric Academic Health Centers: A Blueprint for Integration T2 - Medical Acupuncture TI - Acupuncture in Pediatric Academic Health Centers: A Blueprint for Integration UR - ://WOS:000217806700008 VL - 27 ID - 2207 ER - TY - JOUR AB - OBJECTIVE: To compare self-reported healthcare resource utilisation, paid work loss, unpaid work loss and loss of effectiveness at work due to migraine in a clinic-based adult migraine population. METHODS: The Migraine Background Questionnaire (MBQ) was translated and pilot-tested for use in 25 countries. The questionnaire was then self-administered by patients at a screening visit for 3 phase III clinical trials of rizatriptan [a selective serotonin (5-hydroxytryptamine) 5-HT1B/1D receptor agonist] in 23 US and 78 non-US sites. PARTICIPANTS: Persons 18 to 65 years of age with at least a 6-month history of moderate to severe migraines prior to the screening visit were surveyed. RESULTS: A total of 2670 persons (54.7% Europe, 16.5% Latin America, 23.1% North America, 5.5% other countries) completed the MBQ and had responses which could be analysed. On average, each patient reported 2.78 doctor visits, 0.53 emergency room visits and 0.06 hospitalisations related to migraine per year. Patients self-reported being only 46% effective while on the job with migraine symptoms. Extrapolation of patient self-reported work and productivity loss for the last 4 weeks to an annual basis suggested that clinic-based patients with migraine lose 19.5 workday equivalents (8.3 days due to absenteeism, 11.2 days due to reduced workday equivalents) due to migraine per year. In the US, the annual employer cost of this total migraine-related work loss is estimated to be $US3309 (2000 values) per patient with migraine. The levels of self-reported healthcare resources utilised for migraine and work loss were generally consistent across geographic regions. CONCLUSIONS: The impact of migraine symptoms on healthcare resource utilisation and work loss was similar across most measures in Europe, Latin America, North America and other countries. Total migraine-related work loss due to absenteeism and reduced workday equivalents accounts for most of the economic burden of migraine, regardless of country, in a clinic-based migraine population. AD - Merck & Co., Inc., Whitehouse Station, New Jersey, USA. william_gerth@merck.com AN - 11284383 AU - Gerth, W. C. AU - Carides, G. W. AU - Dasbach, E. J. AU - Visser, W. H. AU - Santanello, N. C. DO - 10.2165/00019053-200119020-00006 DP - NLM ET - 2001/04/04 IS - 2 KW - Adolescent Adult Age Factors *Cost of Illness Data Collection Female Health Resources/*statistics & numerical data Humans Male Middle Aged Migraine Disorders/*economics/epidemiology Sex Characteristics Work/*economics LA - eng N1 - Gerth, W C Carides, G W Dasbach, E J Visser, W H Santanello, N C Journal Article Research Support, Non-U.S. Gov't New Zealand Pharmacoeconomics. 2001;19(2):197-206. doi: 10.2165/00019053-200119020-00006. PY - 2001 SN - 1170-7690 (Print) 1170-7690 SP - 197-206 ST - The multinational impact of migraine symptoms on healthcare utilisation and work loss T2 - Pharmacoeconomics TI - The multinational impact of migraine symptoms on healthcare utilisation and work loss VL - 19 ID - 3712 ER - TY - JOUR AB - Many researchers have studied somatic symptoms in children. However, its association with severe mood dysregulation (SMD) is poorly known. The aim of this study is to detect the presence of SMD in preschool children and to know the prevalence of somatic symptoms and associations with psychopathology, SMD, and aggressiveness. The study population consists of children between 3 to 6 years of age enrolled in Barcelona's kindergarten schools (n = 319). Their parents completed questionnaires about the presence of somatic symptoms in children, absences from school and pediatric visits, child psychiatric symptoms, presence of symptoms of SMD, and aggressiveness. Teachers were also informed about SMD and aggressiveness. Children who complained frequent somatic symptoms (three or more in the last 2 weeks) were compared with those who did not. Two hundred five children (64.3%) reported at least one physical complaint in the 2 weeks preceding the study. One hundred participants (31.3%) reported frequent somatic complaints. Positive associations were found with anxiety symptomatology, separation anxiety, social phobia, pediatric visits, and school absences, but not with aggressiveness or SMD symptoms. Somatic symptoms are common in a sample of preschool children but do not show a positive association with the symptoms of SMD. AN - WOS:000298657300014 AU - Giacobo, R. S. AU - Jane, M. C. AU - Bonillo, A. AU - Ballespi, S. AU - Diaz-Reganon, N. DA - Jan DO - 10.1007/s00431-011-1495-5 IS - 1 N1 - Serra Giacobo, Rodrigo Claustre Jane, Ma Bonillo, Albert Ballespi, Sergi Diaz-Reganon, Natalia Bonillo, Albert/H-9927-2015; Ballespi, Sergi/L-6492-2014 Bonillo, Albert/0000-0002-6141-9708; Ballespi, Sergi/0000-0002-6584-4138 1432-1076 PY - 2012 SN - 0340-6199 SP - 111-119 ST - Somatic symptoms, severe mood dysregulation, and aggressiveness in preschool children T2 - European Journal of Pediatrics TI - Somatic symptoms, severe mood dysregulation, and aggressiveness in preschool children UR - ://WOS:000298657300014 VL - 171 ID - 2460 ER - TY - JOUR AB - Chronic pain is the major complaint of myofascial pain dysfunction syndrome (MPDS) and is a complex problem which involves physical, psychological and social aspects. The etiology of MPDS is multifactorial and the multidisciplinary approach is essential for differential diagnosis and for comprehensive treatment planning. In 1993, the Dental School of Piracicaba-UNICAMP, Brazil, opened a Center for Pain Studies (CPS), staffed by health care providers including, dentists, psychologists, physicians, physiotherapists and phonoaudiologists. The major aims of the CPS are to provide clinical care and to develop basic and applied research. Sixty-two MPDS patients had been admitted to the CPS by 1997. There were 60 females and 2 males, mean age-32.5 years. The mean duration of chronic pain was 48 months. Pain intensity and unpleasantness were measured employing the Visual Analogue Scale. The tendency to develop stress-related diseases was assessed by the Social Readjustment Scale. There was a mean reduction of chronic pain of 69.89% and 71.78% relative to intensity and unpleasantness, respectively. The experience of clinical attendance at a multidisciplinary center showed the relevance of a team consisting of health care providers from different specialties with well-established aims, completely integrated and sensitive enough to understand the painful complaints of MPDS patients. AD - University of Campinas, UNICAMP, São Paulo State, Brazil. AN - 9481982 AU - Gil, I. A. AU - Barbosa, C. M. AU - Pedro, V. M. AU - Silverio, K. C. AU - Goldfarb, D. P. AU - Fusco, V. AU - Navarro, C. M. DA - Jan DO - 10.1080/08869634.1998.11746034 DP - NLM ET - 1998/03/03 IS - 1 KW - Adolescent Adult Brazil Chronic Disease Female Humans Male Middle Aged *Pain Clinics Pain Measurement Social Adjustment Stress, Psychological/physiopathology Temporomandibular Joint Dysfunction Syndrome/physiopathology/psychology/*therapy Time Factors LA - eng N1 - Gil, I A Barbosa, C M Pedro, V M Silverio, K C Goldfarb, D P Fusco, V Navarro, C M Journal Article England Cranio. 1998 Jan;16(1):17-25. doi: 10.1080/08869634.1998.11746034. PY - 1998 SN - 0886-9634 (Print) 0886-9634 SP - 17-25 ST - Multidisciplinary approach to chronic pain from myofascial pain dysfunction syndrome: a four-year experience at a Brazilian center T2 - Cranio TI - Multidisciplinary approach to chronic pain from myofascial pain dysfunction syndrome: a four-year experience at a Brazilian center VL - 16 ID - 3350 ER - TY - JOUR AB - Examined 9-month follow-up data obtained from children and adolescents with sickle cell disease (SCD) and their parents participating in a longitudinal study of pain coping strategies. Of 87 subjects completing the baseline assessment of pain coping strategies, 70 (80%) of their parents completed a structured pain interview assessing their child's health care use and activity reduction during painful episodes over the follow-up period. Regression analyses controlling for age and pain frequency revealed that baseline Coping Attempts were associated with higher levels of school, household, and social activity during painful episodes. Baseline Passive Adherence was associated with more frequent health care contacts during the subsequent 9 months. Increases in Negative Thinking over time were associated with further increases in health care contacts during the follow-up period. Comparing pain coping strategies assessed at baseline to pain coping strategies measured at follow-up revealed that pain coping strategies were relatively stable over time for younger children but changed more for adolescents. AN - WOS:A1993MG28100007 AU - Gil, K. M. AU - Thompson, R. J. AU - Keith, B. R. AU - Totafaucette, M. AU - Noll, S. AU - Kinney, T. R. DA - Oct DO - 10.1093/jpepsy/18.5.621 IS - 5 N1 - Gil, km thompson, rj keith, br totafaucette, m noll, s kinney, tr PY - 1993 SN - 0146-8693 SP - 621-637 ST - SICKLE-CELL DISEASE PAIN IN CHILDREN AND ADOLESCENTS - CHANGE IN PAIN FREQUENCY AND COPING STRATEGIES OVER TIME T2 - Journal of Pediatric Psychology TI - SICKLE-CELL DISEASE PAIN IN CHILDREN AND ADOLESCENTS - CHANGE IN PAIN FREQUENCY AND COPING STRATEGIES OVER TIME UR - ://WOS:A1993MG28100007 VL - 18 ID - 2951 ER - TY - JOUR AB - OBJECTIVE: The purpose of this study was to evaluate standard measures of health behavior for association with back pain among college students using data from the standardized National College Health Assessment survey. This investigation evaluated potential risk factors among a population of students at a Colorado university. METHODS: This cross-sectional study included 963 survey results that were assessed using backward selection logistic regression techniques to evaluate the associations between common college-life health behaviors and back pain occurrence within the past school year. RESULTS: Thirty-eight percent of college students surveyed reported having back pain within the past school year. Investigators found that univariate associations included multiple domains, but only psychosocial factors remained statistically significant in a final regression model and were associated with back pain. Feeling chronically fatigued (odds ratio, 3.89; 95% confidence interval, 1.09-13.86) and being in an emotionally abusive relationship (odds ratio, 2.78; 95% confidence interval, 1.69-4.57) were the factors most strongly associated with back pain in the final model. CONCLUSIONS: Psychosocial factors were identified to be associated with back pain. The prevalence of back pain among this younger population is of significant concern and warrants further investigation to identify contributing factors that may help in the development of interventions to reduce the epidemic of back pain within college students and lessen the burden upon college health providers. AD - Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523-1681, USA. dgilkey@colostate.edu AN - 20170773 AU - Gilkey, D. P. AU - Keefe, T. J. AU - Peel, J. L. AU - Kassab, O. M. AU - Kennedy, C. A. DA - Feb DO - 10.1016/j.jmpt.2009.12.005 DP - NLM ET - 2010/02/23 IS - 2 KW - Adolescent Adult Aged Aged, 80 and over Back Pain/epidemiology/*etiology Cross-Sectional Studies Fatigue/complications Female Health Behavior Humans Logistic Models Male Middle Aged Prevalence Psychology Risk Factors Spouse Abuse *Students/statistics & numerical data Surveys and Questionnaires *Universities Young Adult LA - eng N1 - 1532-6586 Gilkey, David P Keefe, Thomas J Peel, Jennifer L Kassab, Osama M Kennedy, Catherine A Journal Article United States J Manipulative Physiol Ther. 2010 Feb;33(2):88-95. doi: 10.1016/j.jmpt.2009.12.005. PY - 2010 SN - 0161-4754 SP - 88-95 ST - Risk factors associated with back pain: a cross-sectional study of 963 college students T2 - J Manipulative Physiol Ther TI - Risk factors associated with back pain: a cross-sectional study of 963 college students VL - 33 ID - 3790 ER - TY - JOUR AB - This paper describes the development and piloting of the Central Middlesex Hospital Children's Health Diary (CMHCHD) for children and adolescents with sickle cell disease (SCD), and examines the reliability and validity of its key outcome measures. The diary has a semi-structured format to be completed daily, covering general well-being, common symptoms, pain events, coping strategies and the impact of any pain/illness events. Key summary measures consisted of total pain and impact scores for the diary-keeping period. A pilot study was carried out with 25 children with SCD, and 25 matched controls who completed the diary for a four-week period. Compliance with the procedure was satisfactory and adequate reliability was indicated although fatigue affects were observed during the fourth week of record keeping on some variables. The pain score had satisfactory concurrent validity with higher pain scores associated with more school absence (u=88.5,p<.03) and greater disruption of daily life (u=57,P<.01) and demonstrated encouraging construct validity by identifying expected higher rates of limb pain in children with SCD compared with controls (u=196,P<.02). parent and child interview ratings of pain frequency were not associated with quality of life measures, and could not discriminate between the clinical and non-clinical population. Compared with both parent and child interview ratings of pain frequency, the total pain score was a more accurate predictor of the impact of pain in children's everyday life (F(47)=10.80,p<.001). In conclusion, the CMHCHD shows considerable potential both for research, improving clinical assessment, and for enhancing coping strategies of children and their families. AN - WOS:A1997XA40300003 AU - Gill, L. J. AU - Shand, P. A. X. AU - Fuggle, P. AU - Dugan, B. AU - Davies, S. C. DA - May DO - 10.1111/j.2044-8287.1997.tb00529.x N1 - Gill, LJ Shand, PAX Fuggle, P Dugan, B Davies, SC 2044-8287 2 PY - 1997 SN - 1359-107X SP - 131-140 ST - Pain assessment for children with sickle cell disease: Improved validity of diary keeping versus interview ratings T2 - British Journal of Health Psychology TI - Pain assessment for children with sickle cell disease: Improved validity of diary keeping versus interview ratings UR - ://WOS:A1997XA40300003 VL - 2 ID - 2909 ER - TY - JOUR AB - PURPOSE: Deep brain stimulation is now widely accepted as an effective treatment for children with primary generalized dystonia. More variable results are reported in secondary dystonias and its efficacy in this heterogeneous group has not been fully elucidated. Deep brain stimulation outcomes are typically reported using impairment-focused measures, such as the Burke-Fahn-Marsden Dystonia Rating Scale, which provide little information about function and participation outcomes or changes in non-motor areas. The aim is to demonstrate that in some cases of secondary dystonia, the sole use of impairment level measures, such as the Burke-Fahn-Marsden Dystonia Rating Scale, may be insufficient to fully evaluate outcome following deep brain stimulation. METHODS: Six paediatric cases who underwent deep brain stimulation surgery with a minimum of one year follow up were selected on the basis of apparent non-response to deep brain stimulation, defined as a clinically insignificant change in the Burke-Fahn-Marsden Dystonia Movement Scale (<20%), but where other evaluation measures demonstrated clinical efficacy across several domains. RESULTS: Despite no significant change in Burke-Fahn-Marsden Dystonia Rating Scale scores following deep brain stimulation, parallel outcome measures demonstrated significant benefit in a range of child and family-centred goal areas including: pain and comfort, school attendance, seating tolerance, access to assistive technology and in some cases carer burden. CONCLUSIONS: Sole use of impairment-focused measures, are limited in scope to evaluate outcome following deep brain stimulation, particularly in secondary dystonias. Systematic study of effects across multiple dimensions of disability is needed to determine what deep brain stimulation offers patients in terms of function, participation, care, comfort and quality of life. Deep brain stimulation may offer meaningful change across multiple domains of functioning, disability and health even in the absence of significant change in dystonia rating scales. AD - Complex Motor Disorders Service, Evelina Children's Hospital, Guy's & St Thomas' NHS Foundation Trust, London, UK. hortensia.gimeno@gstt.nhs.uk AN - 22258088 AU - Gimeno, H. AU - Tustin, K. AU - Selway, R. AU - Lin, J. P. DA - Sep DO - 10.1016/j.ejpn.2011.12.014 DP - NLM ET - 2012/01/20 IS - 5 KW - Adolescent Child Child, Preschool *Deep Brain Stimulation Dystonic Disorders/physiopathology/*therapy Female Follow-Up Studies Globus Pallidus/*physiopathology Goals Humans Male Pain Management Severity of Illness Index Treatment Outcome LA - eng N1 - 1532-2130 Gimeno, Hortensia Tustin, Kylee Selway, Richard Lin, Jean-Pierre Journal Article Research Support, Non-U.S. Gov't England Eur J Paediatr Neurol. 2012 Sep;16(5):501-8. doi: 10.1016/j.ejpn.2011.12.014. Epub 2012 Jan 17. PY - 2012 SN - 1090-3798 SP - 501-8 ST - Beyond the Burke-Fahn-Marsden Dystonia Rating Scale: deep brain stimulation in childhood secondary dystonia T2 - Eur J Paediatr Neurol TI - Beyond the Burke-Fahn-Marsden Dystonia Rating Scale: deep brain stimulation in childhood secondary dystonia VL - 16 ID - 3480 ER - TY - JOUR AB - Objectives: The objective was to identify clinical, social, and environmental risk factors for increased emergency department (ED) use in children with sickle cell disease (SCD). Methods: This study was a secondary analysis of ED utilization data from the international multicenter Silent Cerebral Infarct Transfusion (SIT) trial. Between December 2004 and June 2010, baseline demographic, clinical, and laboratory data were collected from children with SCD participating in the trial. The primary outcome was the frequency of ED visits for pain. A secondary outcome was the frequency of ED visits for acute chest syndrome. Results: The sample included 985 children from the United States, Canada, England, and France, for a total of 2,955 patient-years of data. There were 0.74 ED visits for pain per patient-year. A past medical history of asthma was associated with an increased risk of ED utilization for both pain (rate ratio [RR] = 1.28, 95% confidence interval [CI] = 1.04 to 1.58) and acute chest syndrome (RR = 1.60, 95% CI = 1.03 to 2.49). Exposure to environmental tobacco smoke in the home was associated with 73% more ED visits for acute chest syndrome (RR = 1.73, 95% CI = 1.09 to 2.74). Each $10,000 increase in household income was associated with 5% fewer ED visits for pain (RR = 0.95, 95% CI = 0.91 to 1.00, p = 0.05). The association between low income and ED utilization was not significantly different in the United States versus countries with universal health care (p = 0.51). Conclusions: Asthma and exposure to environmental tobacco smoke are potentially modifiable risk factors for greater ED use in children with SCD. Low income is associated with greater ED use for SCD pain in countries with and without universal health care. ACADEMIC EMERGENCY MEDICINE 2012; 19: 664-672 (C) 2012 by the Society for Academic Emergency Medicine AN - WOS:000305740800007 AU - Glassberg, J. A. AU - Wang, J. AU - Cohen, R. AU - Richardson, L. D. AU - DeBaun, M. R. DA - Jun DO - 10.1111/j.1553-2712.2012.01364.x IS - 6 N1 - Glassberg, Jeffrey A. Wang, Jason Cohen, Robyn Richardson, Lynne D. DeBaun, Michael R. Cohen, Robyn/AAC-9326-2019; Wang, Jason/AAG-8248-2019 Cohen, Robyn/0000-0002-6902-3118; 1553-2712 PY - 2012 SN - 1069-6563 SP - 664-672 ST - Risk Factors for Increased ED Utilization in a Multinational Cohort of Children With Sickle Cell Disease T2 - Academic Emergency Medicine TI - Risk Factors for Increased ED Utilization in a Multinational Cohort of Children With Sickle Cell Disease UR - ://WOS:000305740800007 VL - 19 ID - 2428 ER - TY - JOUR AB - The Lidocaine 5% plaster is licensed for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia in adult patients over 18 years of age. Studies in adults also demonstrate efficacy of Lidocaine 5% plasters in other neuropathic pain conditions. Case reports and experience suggested efficacy of Lidocaine 5% plasters in children and adolescents with localised neuropathic pain. Initiated by the Pain in Children Special Interest Group (PICSIG) of the British Pain Society, a 3-year prospective multicentre service evaluation was undertaken to document the usage and efficacy of the Lidocaine 5% plaster in paediatric patients being managed by paediatric pain teams in the United Kingdom. Five paediatric pain teams provided anonymised data pre-treatment and 3-6 months after commencing Lidocaine 5% plaster. Changes in pain score, function, sleep and continuing use were evaluated. Data were obtained for 115 patients; age range 5-18 years (mean: 12 years). Diagnosis and site of application varied. Benefit from use of a Lidocaine 5% plaster in an individual was deemed if two or more of the following were reported: reduction in pain score, functional improvement, sleep improvement and continuing use of Lidocaine 5% plaster. Benefit was recorded for 79 patients (69%); 32 patients were recorded as receiving no benefit and data were unavailable for 4 patients, and 7 patients reported minor skin reactions. This prospective service evaluation supports the efficacy of the Lidocaine 5% plaster in children and adolescents with localised neuropathic pain and confirms tolerability and safety. It is the opinion of the PICSIG of the British Pain Society that the Lidocaine 5% plaster should be considered early in the multidisciplinary management of localised neuropathic pain in children and adolescents. AD - Sheffield Children's NHS Foundation Trust, Sheffield, UK. AN - 30057764 AU - Goddard, J. M. AU - Reaney, R. L. C2 - PMC6058457 DA - Aug DO - 10.1177/2049463718756431 DP - NLM ET - 2018/07/31 IS - 3 KW - Lidocaine Versatis adolescent child lidocaine patch lidocaine plaster neuropathic pain school child respect to the research, authorship and/or publication of this article. LA - eng N1 - 2049-4645 Goddard, John M Orcid: 0000-0002-6953-3353 Reaney, Rebecca L Journal Article Br J Pain. 2018 Aug;12(3):189-193. doi: 10.1177/2049463718756431. Epub 2018 Jan 31. PY - 2018 SN - 2049-4637 (Print) 2049-4637 SP - 189-193 ST - Lidocaine 5%-medicated plaster (Versatis) for localised neuropathic pain: results of a multicentre evaluation of use in children and adolescents T2 - Br J Pain TI - Lidocaine 5%-medicated plaster (Versatis) for localised neuropathic pain: results of a multicentre evaluation of use in children and adolescents VL - 12 ID - 4088 ER - TY - JOUR AB - Introduction: Assessment of outcomes from health interventions are of increasing importance, primarily to identify effective and safe treatment, but also to justify funding decisions. The Bath Adolescent Pain Questionnaire (BAPQ) is a self-report questionnaire, validated in 11-18year olds, assessing the impact of pain in multiple domains of adolescent life. The similarly validated Bath Adolescent Pain Questionnaire for Parents (BAPQ-P) uses the same domains as the BAPQ, assessing the functioning and development of the adolescent from the parents' perspective. Methods: We conducted a prospective study, planning to routinely collect BAPQ/BAPQ-P data at initial assessment and 6months later. All patients aged between 5 and 19 attending our chronic pain clinic for the first time between December 2009 and December 2014 were mailed BAPQ and BAPQ-P questionnaires before the first appointment and 6months after the first appointment. Results: In total, 376 of 386 families returned questionnaires at time 0 and 96 after 6months, 26% of those responded at time 0. We found statistically significant differences on patients' BAPQ questionnaires from 0 to 6 months showing improvement in all domains. A different result was found on parents' questionnaires where we only found a statistically significant difference on daily and emotional functioning. When comparing patient and parent questionnaires at 0 and 6 months, we found statistically significant differences between patients' and parents' questionnaires in the daily functioning and development domains. Conclusion: We believe BAPQ and BAPQ-P measurement proved useful tools to assess response to pain management input in adolescents over a 6-month period. Our experience and results suggest that these tools can, with appropriate administrative support, be used in routine clinical practice to assess patient outcomes. We also believe that BAPQ and BAPQ-P measurements have a utility to audit pain clinic activity and potentially a use in demonstrating beneficial outcomes to commissioners. AN - WOS:000539604600001 AU - Goddard, J. M. AU - Robinson, J. AU - Hiscock, R. C7 - 2049463720927067 DA - May DO - 10.1177/2049463720927067 IS - 2 N1 - Goddard, John M. Robinson, Jane Hiscock, Rachel Goddard, John/0000-0002-6953-3353 2049-4645 PY - 2021 SN - 2049-4637 SP - 155-162 ST - Routine use of the Bath Adolescent Pain Questionnaire in a paediatric pain clinic T2 - British Journal of Pain TI - Routine use of the Bath Adolescent Pain Questionnaire in a paediatric pain clinic UR - ://WOS:000539604600001 VL - 15 ID - 1816 ER - TY - JOUR AB - A 17-year-old girl with temporomandibular joint disease who had been treated with the usual types of treatment for 8 1/2 years by multiple clinicians was treated using hypnosis as an adjunct. The treatment, which is described in detail, was successful for 6 months until the patient transferred to an urban college where additional academic and personal pressures caused her bruxism symptoms to reappear. Probable causes of the relapse are discussed. AN - 2712013 AU - Golan, H. P. DA - Apr DO - 10.1080/00029157.1989.10402783 DP - NLM ET - 1989/04/01 IS - 4 KW - Adolescent Bruxism/therapy Female Humans Hypnosis/*methods Temporomandibular Joint Dysfunction Syndrome/*therapy LA - eng N1 - Golan, H P Case Reports Journal Article United States Am J Clin Hypn. 1989 Apr;31(4):269-74. doi: 10.1080/00029157.1989.10402783. PY - 1989 SN - 0002-9157 (Print) 0002-9157 SP - 269-74 ST - Temporomandibular joint disease treated with hypnosis T2 - Am J Clin Hypn TI - Temporomandibular joint disease treated with hypnosis VL - 31 ID - 3610 ER - TY - JOUR AB - IntroductionOver 80% of children experience compromise in functioning following a fracture. Digital media may improve caregiver knowledge of managing fracture pain at home. OBJECTIVES: To determine whether an educational video was superior to an interactive web-based module (WBM) and verbal instructions, the standard of care (SOC). METHODS: This randomized trial included caregivers of children 0-17 years presenting to the emergency department (ED) with non-operative fractures. Primary outcome was the gain score (pre-post intervention) on a 21-item questionnaire testing knowledge surrounding pain recognition and management for children with fractures. Secondary outcomes included survey of caregiver confidence in managing pain (five-item Likert scale), number of days with difficulty sleeping, before return to a normal diet, and work/school missed. RESULTS: We analyzed 311 participants (WBM 99; video 108; SOC 104) with a mean (SD) child age of 9.6 (4.2) years, of which 125/311 (40.2%) were female. The video (delta=2.3, 95% CI: 1.3, 3.3; p<0.001) and WBM (delta=1.6; 95% CI: 0.5, 2.6; p=0.002) groups had significantly greater gain scores than the SOC group. The mean video gain score was not significantly greater than WBM (delta=0.7; 95% CI: -0.3, 1.8; p=0.25). There were no significant differences in caregiver confidence (p=0.4), number of absent school days (p=0.43), nights with difficulty sleeping (p=0.94), days before return to a normal diet (p=0.07), or workdays missed (p=0.95). CONCLUSIONS: A web-based module and online video are superior to verbal instructions for improving caregiver knowledge on management of children's fracture pain without improvement in functional outcomes. AD - *Department of Paediatrics,Western University,London,ON. ‡Department of Pediatrics,University of Alberta,Women and Children's Health Research Institute,Edmonton,AB. §Department of Pediatrics,Medical College of Wisconsin,Milwaukee,WI. ¶Division of Paediatric Emergency Medicine,Western University,London,ON. AN - 29041997 AU - Golden-Plotnik, S. AU - Ali, S. AU - Drendel, A. L. AU - Wong, T. AU - Ferlisi, F. AU - Todorovich, S. AU - Canton, K. AU - Miller, M. AU - Younan, J. AU - Elsie, S. AU - Poonai, N. DA - Nov DO - 10.1017/cem.2017.414 DP - NLM ET - 2017/10/19 IS - 6 KW - Adolescent Caregivers/*education Child Child, Preschool Emergency Service, Hospital Female Fractures, Bone/*complications/diagnosis Health Education/*methods Health Knowledge, Attitudes, Practice Humans Infant Infant, Newborn *Internet Male Pain/*diagnosis/etiology Pain Management/*methods Retrospective Studies Video Recording/*methods *digital education *fracture *paediatrics *pain LA - eng N1 - 1481-8043 Golden-Plotnik, Stevi Ali, Samina Drendel, Amy L Wong, Tammy Ferlisi, Frank Todorovich, Sydney Canton, Kyle Miller, Michael Younan, Julia Elsie, Sharlene Poonai, Naveen Journal Article Randomized Controlled Trial England CJEM. 2018 Nov;20(6):882-891. doi: 10.1017/cem.2017.414. Epub 2017 Oct 18. PY - 2018 SN - 1481-8035 SP - 882-891 ST - A Web-based module and online video for pain management education for caregivers of children with fractures: A randomized controlled trial T2 - Cjem TI - A Web-based module and online video for pain management education for caregivers of children with fractures: A randomized controlled trial VL - 20 ID - 3557 ER - TY - JOUR AB - Background: Despite the wealth of clinical research carried out in children with juvenile idiopathic arthritis (JIA), little is known about the emotional experiences of their parents. This article describes the predominant emotional experiences reported by parents of children with JIA in two Canadian cities. Methods: Research participants included 15 experienced parents and 8 novice parents (<6 months since children's JIA diagnosis). Their children were 2 to 16 years old with various JIA categories. A qualitative dataset including audio recordings and verbatim transcripts of three focus groups, and written reports of 59 reciprocal interviews (parents interviewing each other) were examined by a multidisciplinary research team following a four-step qualitative analytical process. Results: Parents of children with JIA experienced recurrent mixed negative and positive emotions that varied over time. Between disease onset and diagnosis, mounting anxiety, fear and confusion were the predominant emotions. Shortly after diagnosis there were shock, disbelief, and fear, with a sense of having being blindsided by the disease. At times of disease quiescence there was hope and gratitude, but also fatigue and frustration with ongoing treatment and fear of flares. During periods of increasing or ongoing symptoms there was admiration and sympathy for the courageous way children coped with JIA, as well as sorrow and frustration for ongoing pain and limitations. There were at times, frustration and indignation with peers and teachers unable to understand the child's fluctuations in physical activity and schoolwork. Throughout the disease, parents felt an underlying anxiety and powerlessness. Conclusions: Parents of children with JIA described complex emotional journeys akin to the recurring ups and downs of rollercoaster rides, instead of ordered emotional phases ending in resolution. This has implications for healthcare providers who need to be aware of the complexity of these emotional journeys to support parents more effectively, thereby helping improve patient outcomes. AN - WOS:000371687700001 AU - Gomez-Ramirez, O. AU - Gibbon, M. AU - Berard, R. AU - Jurencak, R. AU - Green, J. AU - Tucker, L. AU - Shiff, N. AU - Guzman, J. C7 - 13 DA - Mar DO - 10.1186/s12969-016-0073-9 N1 - Gomez-Ramirez, Oralia Gibbon, Michele Berard, Roberta Jurencak, Roman Green, Jayne Tucker, Lori Shiff, Natalie Guzman, Jaime Guzman, Jaime/0000-0001-8977-2581; Gomez-Ramirez, Oralia/0000-0001-6632-564X; Berard, Roberta/0000-0003-2780-0617 1546-0096 PY - 2016 ST - A recurring rollercoaster ride: a qualitative study of the emotional experiences of parents of children with juvenile idiopathic arthritis T2 - Pediatric Rheumatology TI - A recurring rollercoaster ride: a qualitative study of the emotional experiences of parents of children with juvenile idiopathic arthritis UR - ://WOS:000371687700001 VL - 14 ID - 2178 ER - TY - JOUR AB - BACKGROUND: Previous research has shown that various childhood risk factors are related to depression and chronic physical conditions (CPCs) later in life. However, little is known about risk factors associated with comorbidity for these conditions. The purpose of this study was to examine the association between individual (school performance, childhood physical and sexual abuse) and family risk variables (socioeconomic status, parental mental health, medical condition, and functional limitation) with depression only, chronic pain conditions (back pain and headaches) or other CPCs (respiratory, cardiovascular and digestive disorders, and diabetes) and the comorbidity of either CPC category with depression assessed in early adulthood. METHODS: We used data from the Ontario Child Health Study, a prospective, population-based study of 3294 children (ages 4-16) enrolled in 1983 and meeting inclusion criteria at follow-up in 2001 (N = 1475; ages 21-35 years). RESULTS: Using multinomial logistic regression models, controlling for sex and age, childhood history of physical abuse was associated with most outcomes (OR = 1.86, 95% confidence interval [CI] 1.16-2.97 to 4.36, 95% CI, 1.74-10.97). Parental mental health, childhood functional limitation, childhood history of sexual abuse and family functioning were all related to comorbid depression and chronic pain conditions. Parental mental health was also related to increased risk of other CPCs (ORs = 1.66; 95% CI, 1.08-2.55). CONCLUSION: We found that the greatest disease risk (comorbid depression and chronic pain conditions) was related to the greatest number of childhood risk factors. Although there was some evidence of specificity, there was overlap in childhood physical abuse predicting almost all outcomes. Efforts targeting the prevention and treatment of childhood maltreatment are critical in order to prevent the long lasting impact of childhood adversity on mental and physical outcomes in early adulthood. AD - McMaster University, Department of Psychiatry and Behavioural Neuroscience, Offord Centre for Child Studies, 1280 Main Street West, Chedoke Site, Patterson Building, Hamilton, ON L8S 3K1, Canada. gonzal@mcmaster.ca AN - 22959202 AU - Gonzalez, A. AU - Boyle, M. H. AU - Kyu, H. H. AU - Georgiades, K. AU - Duncan, L. AU - MacMillan, H. L. DA - Nov DO - 10.1016/j.jpsychires.2012.08.004 DP - NLM ET - 2012/09/11 IS - 11 KW - Adolescent Adult Child Child, Preschool Chronic Disease Comorbidity Depressive Disorder/*epidemiology Family/*psychology Female Health Surveys Humans Male Ontario/epidemiology Prospective Studies Somatoform Disorders/*epidemiology Young Adult LA - eng N1 - 1879-1379 Gonzalez, Andrea Boyle, Michael H Kyu, Hwme Hwme Georgiades, Katholiki Duncan, Laura MacMillan, Harriet L Journal Article England J Psychiatr Res. 2012 Nov;46(11):1475-82. doi: 10.1016/j.jpsychires.2012.08.004. Epub 2012 Sep 6. PY - 2012 SN - 0022-3956 SP - 1475-82 ST - Childhood and family influences on depression, chronic physical conditions, and their comorbidity: findings from the Ontario Child Health Study T2 - J Psychiatr Res TI - Childhood and family influences on depression, chronic physical conditions, and their comorbidity: findings from the Ontario Child Health Study VL - 46 ID - 3801 ER - TY - JOUR AB - Background: This study aimed to assess pain and quality of life in a large cohort of patients with multiple hereditary exostoses. Methods: All 322 known patients with multiple hereditary exostoses in the Netherlands were asked to participate. An age-specific questionnaire was sent to children (less than eighteen years old) and adults. The questionnaire focused on pain, daily activities, and school and/or professional situation. Adults also filled out the RAND-36 questionnaire.Results were statistically analyzed with use of the SPSS 15.0 software and with the chi-square test and multiple logistic regression. A p value of < 0.05 was regarded as significant. Results: Two hundred and eighty-three patients (88%), including 184 adults (65%) and ninety-nine children (35%), completed the questionnaire. Multiple hereditary exostoses resulted in various physical and social consequences. The majority of adults (119) were employed; however, thirty-three (28%) had changed jobs because of the symptoms of multiple hereditary exostoses and twenty-five (21%) required adjustments in their working environment. Of the sixty-five adults who were not employed, thirteen were medically unfit to work. Of eighty-five children attending school, forty-five (53%) experienced problems at school. The symptoms of multiple hereditary exostoses caused twenty-seven children (27%) and eighty-five adults (46%) to stop participating in sporting activities. Pain was the greatest problem, with sixty-two children (63%) and 152 adults (83%) who reported recent pain. On multivariate analysis, pain in adults was correlated most significantly with age and problems at work, and pain in children was correlated with the perception of the disease and problems at school. Adult patients with multiple hereditary exostoses had a lower quality of life than the Dutch reference groups, with lower scores on six of eight RAND-36 subscales. Conclusions: Our study confirms that multiple hereditary exostoses is a chronic disease causing a profound impact on quality of life. The results suggest that pain is not the only problem associated with multiple hereditary exostoses, as it has an extensive influence on daily activities, as well as on social and psychological well-being, causing significant disability. AN - WOS:000304977700006 AU - Goud, A. L. AU - de Lange, J. AU - Scholtes, V. A. B. AU - Bulstra, S. K. AU - Ham, S. J. DA - Jun DO - 10.2106/jbjs.K.00406 IS - 11 N1 - Goud, A. L. de Lange, J. Scholtes, V. A. B. Bulstra, S. K. Ham, S. J. PY - 2012 SN - 0021-9355 SP - 1013-1020 ST - Pain, Physical and Social Functioning, and Quality of Life in Individuals with Multiple Hereditary Exostoses in the Netherlands T2 - Journal of Bone and Joint Surgery-American Volume TI - Pain, Physical and Social Functioning, and Quality of Life in Individuals with Multiple Hereditary Exostoses in the Netherlands UR - ://WOS:000304977700006 VL - 94A ID - 2427 ER - TY - JOUR AB - Study Objective: To determine the utilization of anesthesia resources by children with complex special health care needs. Design: Observational, inception cohort study of medical records. Setting: Urban, pediatric, tertiary-care hospital. Measurements: All general anesthetic cases were screened for preexisting complex special health care needs. Medical records were reviewed for demographic, clinical, and outcome data. Main Results: 435 children with complex special health care needs accounted for 479 delivered general anesthetic cases. This figure represented 14% of the total 3,437 cases presenting during the study period. It also represented 22% (49 of 224) of all cancellations. Down syndrome was the most identifiable developmental disorder (n = 43, 9%). Another 143 (30%) cases showed preexisting technology dependence. Scheduled surgical procedures (n = 425, 89%) comprised the majority of cases. Intraoperative and recovery room complications occurred in 6 (1%) and 133 (28%) cases, respectively. Eleven (2.3%) cases required unplanned post-anesthetic hospital ward or pediatric intensive care unit admission. Documentation of health care proxy or resuscitation status was not identified in any child under 18 years, and in only 4 of 33 children older than 18 years. Conclusions: Children with complex special health care needs represented one out of 7 of all pediatric general anesthetic cases at a tertiary-care, academic center. (C) 2009 Elsevier Inc. All rights reserved. AN - WOS:000266687300003 AU - Graham, R. J. AU - Wachendorf, M. T. AU - Burns, J. P. AU - Mancuso, T. J. DA - May DO - 10.1016/j.jclinane.2008.06.033 IS - 3 N1 - Graham, Robert J. Wachendorf, Maria T. Burns, Jeffery P. Mancuso, Thomas J. Graham, Robert Joel Scadron/AAJ-9835-2021 Graham, Robert Joel Scadron/0000-0002-8659-6313 1873-4529 PY - 2009 SN - 0952-8180 SP - 165-172 ST - Successful and safe delivery of anesthesia and perioperative care for children with complex special health care needs T2 - Journal of Clinical Anesthesia TI - Successful and safe delivery of anesthesia and perioperative care for children with complex special health care needs UR - ://WOS:000266687300003 VL - 21 ID - 2605 ER - TY - JOUR AB - The relationships among depression, anxiety, and quality of life were tested, as were the effects of age, gender, and pain frequency on these variables in children (n = 44) and adolescents (n = 31) with sickle cell disease. Participants completed the Revised Child Anxiety and Depression Scale (ROADS) and the Pediatric Quality of Life (PedQL Generic Model). The mean and standard deviation for summary RCADS scores for the majority of participants were below the clinical thresholds of T < 65, indicating low risk for depression (n = 65; 89.3%) and anxiety (n = 70; 93.3%). The subscale scores for the different dimensions of QOL health were a) psychosocial (73.3 ± 15.9), b) emotional (75.0 ± 20.7), c) social (80.8 ± 19.1), d) school functioning (64.0 ≥ 19.8), and e) physical (77.4 ± 17.4). Significant negative correlations were found between mean total quality of life scores and symptoms of a) general anxiety (r = -0.51, p < 0.0001), b) depression (r = -0.66, p < 0.0001), c) obsessive compulsive (r = -0.53, p < 0.0001), d) panic (r = -0.60, p < 0.0001), and e) social phobia (r = -0.57, p < 0.0001). Age and gender did not have significant effects on risk for depression and anxiety or poor QOL. Pain frequency also did not have significant effects on the risk for depression and anxiety. Findings suggest that health care providers need to screen for anxiety and depression, and make referrals for early interventions to improve quality of life and promote school function in youth with sickle cell disease. AN - 27468512 AU - Graves, J. K. AU - Hodge, C. AU - Jacob, E. DA - May-Jun DP - NLM ET - 2016/07/30 IS - 3 KW - Adolescent Anemia, Sickle Cell/*physiopathology/psychology Anxiety/*complications Child Depression/*complications Education, Nursing, Continuing Humans *Quality of Life LA - eng N1 - Graves, J Kelly Hodge, Christopher Jacob, Eufemia 1RC1 HL100301-01/RC/CCR NIH HHS/United States Journal Article Research Support, N.I.H., Extramural Review United States Pediatr Nurs. 2016 May-Jun;42(3):113-9, 144. PY - 2016 SN - 0097-9805 (Print) 0097-9805 SP - 113-9, 144 ST - Depression, Anxiety, and Quality of Life In Children and Adolescents With Sickle Cell Disease T2 - Pediatr Nurs TI - Depression, Anxiety, and Quality of Life In Children and Adolescents With Sickle Cell Disease VL - 42 ID - 3687 ER - TY - JOUR AB - This article presents 4 studies (N = 1,413) describing the development and validation of the Child and Adolescent Mindfulness Measure (CAMM). In Study 1 (n = 428), the authors determined procedures for item development and examined comprehensibility of the initial 25 items. In Study 2 (n = 334), they reduced the initial item pool from 25 to 10 items through exploratory factor analysis. Study 3 (n = 332) evaluated the final 10-item measure in a cross-validation sample, and Study 4 (n = 319) determined validity coefficients for the CAMM using bivariate and partial correlations with relevant variables. Results suggest that the CAMM is a developmentally appropriate measure with adequate internal consistency. As expected, CAMM scores were positively correlated with quality of life, academic competence, and social skills and negatively correlated with somatic complaints, internalizing symptoms, and externalizing behavior problems. Correlations were reduced but generally still significant after controlling for the effects of 2 overlapping processes (thought suppression and psychological inflexibility). Overall, results suggest that the CAMM may be a useful measure of mindfulness skills for school-aged children and adolescents. AN - WOS:000294624100005 AU - Greco, L. A. AU - Baer, R. A. AU - Smith, G. T. DA - Sep DO - 10.1037/a0022819 IS - 3 N1 - Greco, Laurie A. Baer, Ruth A. Smith, Gregory T. 1939-134x PY - 2011 SN - 1040-3590 SP - 606-614 ST - Assessing Mindfulness in Children and Adolescents: Development and Validation of the Child and Adolescent Mindfulness Measure (CAMM) T2 - Psychological Assessment TI - Assessing Mindfulness in Children and Adolescents: Development and Validation of the Child and Adolescent Mindfulness Measure (CAMM) UR - ://WOS:000294624100005 VL - 23 ID - 2481 ER - TY - JOUR AB - Recurrent headache, abdominal and musculoskeletal pain are common in adolescents and it is therefore important to understand their impact on the transitional period from childhood to adulthood. However, studies of the prevalence over time and implications on educational outcomes are still limited, especially regarding multiple pain symptoms. The present study material consists of questionnaire surveys, completed in 2000 and 2008, including two study populations of 9th grade adolescents aged 15 living in West Sweden (n = 20 877). Pain symptoms and demographic variables were based on self-reports from the questionnaires, and school grades were obtained from Statistics Sweden after the student had finished their 9th grade. Between 2000 and 2008, the prevalence of abdominal pain increased among Swedish adolescents (largest increase in girls); the prevalence of headache increased only in girls; the prevalence of pain in upper body decreased only in boys. School grades were significantly lower among those with headache or abdominal pain. Among students with low school grades (10th percentile) the estimated difference between those having any of the symptoms or none were -27 school grade units (95% confidence interval for girls (-27.8; -26.0), for boys (-27.6; -25.5). Both symptoms being present pronounced the association. Low parental education increased the negative effect of symptoms on school grades, most pronounced in the group with the lowest grades. In conclusion, identification of pain symptoms may improve academic achievements, especially in students with multiple symptoms and with parents having low education. Further intervention studies are need. AN - WOS:000452307600066 AU - Grimby-Ekman, A. AU - Aberg, M. AU - Toren, K. AU - Brisman, J. AU - Hagberg, M. AU - Kim, J. L. C7 - e0208435 DA - Dec DO - 10.1371/journal.pone.0208435 IS - 12 N1 - Grimby-Ekman, Anna Aberg, Maria Toren, Kjell Brisman, Jonas Hagberg, Mats Kim, Jeong-Lim Aberg, Maria/R-4001-2016; Grimby-Ekman, Anna/M-8049-2016 Hagberg, Mats/0000-0002-1182-8239; Grimby-Ekman, Anna/0000-0002-9408-6065; Aberg, Maria/0000-0002-0323-1061 PY - 2018 SN - 1932-6203 ST - Pain could negatively affect school grades - Swedish middle school students with low school grades most affected T2 - Plos One TI - Pain could negatively affect school grades - Swedish middle school students with low school grades most affected UR - ://WOS:000452307600066 VL - 13 ID - 1974 ER - TY - JOUR AB - OBJECTIVE: The objective of this study was to estimate the national burden of school absenteeism associated with pain among 6 to 17-year-old children in the United States. METHODS: Data were analyzed from a large, nationally representative sample from the 2012 National Health Interview Survey. Associations between pain and school absence were analyzed using multivariate negative binomial models controlling for sociodemographic and clinical characteristics. RESULTS: The sample contained 8641 participants, of whom 30.3% reported pain over the preceding 12 months. Mean number of parent-reported school days missed across the entire sample was 3 per child; however pain was associated with an additional 1.5 reported missed school days per child. Furthermore, pain was associated with higher rates of chronic absenteeism (missing >15 d of school): 6.1% of children with pain was chronically absent as compared with 1.3% of children without pain. Extrapolated to the nation, childhood pain in the United States was associated with 22.2 million additional days of missed school, whereas childhood asthma, in comparison, was associated with 8 million additional days of school missed. DISCUSSION: Associations between pain and school absenteeism highlight the need for interventions aimed at improving school attendance among children with pain. AU - Groenewald, Cornelius B. AU - Giles, Marian AU - Palermo, Tonya M. DA - 2019/06// DO - 10.1097/AJP.0000000000000701 DP - PubMed IS - 6 J2 - Clin J Pain KW - Absenteeism Adolescent Asthma Child Cost of Illness Humans Pain Schools Socioeconomic Factors Students United States LA - eng PY - 2019 SN - 1536-5409 SP - 525-531 ST - School Absence Associated With Childhood Pain in the United States T2 - The Clinical Journal of Pain TI - School Absence Associated With Childhood Pain in the United States UR - http://www.ncbi.nlm.nih.gov/pubmed/30844952 VL - 35 ID - 59 ER - TY - JOUR AB - OBJECTIVE: The purpose of this study was to determine the association between presence of chronic pain and school functioning among school-aged children (6 to 17 y) using the most recent United States national data. MATERIALS AND METHODS: Secondary data analyses of the 2016-2017 National Survey of Children's Health. Parents (n=48,254) reported on whether their child had chronic pain over the past 12 months. Parents also reported on school functioning including (1) engagement with school, (2) number of school days missed, (3) problems at school, (4) repeating a grade, and (5) diagnosis of a learning disability. Children with chronic pain were compared with children without chronic pain using multivariate logistic regression models. We also stratified analysis according to age and sex. RESULTS: In multivariate analyses, children with pain were more likely to have low school engagement (adjusted odds ratio [OR]: 1.4, 95% confidence interval [CI]: 1.0-1.9), be chronically absent (OR: 4.2, 95% CI: 3.0-5.8), have school-related problems (OR: 1.9, 95% CI: 1.5-2.3), repeat a grade (OR: 1.4, 95% CI: 1.0-2.0), and be diagnosed with a learning disability (OR: 1.6, 95% CI: 1.1-2.5). In stratified analyses, associations between chronic pain and school measures were strongest among adolescents (15 to 17 y of age) and males. DISCUSSION: This study extends evidence linking chronic pain status to poorer school functioning in a large, national sample. Poor school functioning is a pressing public concern affecting children with chronic pain. Health care providers, educators, policymakers, and families should work together to ensure that needs are met for this vulnerable population. AU - Groenewald, Cornelius B. AU - Tham, See Wan AU - Palermo, Tonya M. DA - 2020/09// DO - 10.1097/AJP.0000000000000850 DP - PubMed IS - 9 J2 - Clin J Pain LA - eng PY - 2020 SN - 1536-5409 SP - 693-699 ST - Impaired School Functioning in Children With Chronic Pain T2 - The Clinical Journal of Pain TI - Impaired School Functioning in Children With Chronic Pain: A National Perspective UR - http://www.ncbi.nlm.nih.gov/pubmed/32487871 VL - 36 ID - 57 ER - TY - JOUR AB - This article reports the findings of a metanalytic review of self-control therapies for children with internalizing disorders with symptoms of clinically significant severity. A total of 22 studies testing four different types of self-control interventions were reviewed. Characteristics of the studies reviewed are presented and discussed. Self-control therapy was found to be effective with internalizing disorders in general, but to be more effective with disorders primarily affecting mood than with somatic disorders. Self-control therapy appeared to result in lasting, socially significant changes in behavior and was relatively inexpensive to administer. Factors which may impact the effectiveness of self-control therapy are (a) use of more than one self-control treatment per intervention, (b) group therapy as opposed to individual therapy, and (c) self-control therapy with older versus younger children. Limitations of the study are discussed and suggestions for areas of future research are made. AN - WOS:A1992JD52100005 AU - Grossman, P. B. AU - Hughes, J. N. IS - 2 N1 - Grossman, pb hughes, jn PY - 1992 SN - 0279-6015 SP - 229-245 ST - SELF-CONTROL INTERVENTIONS WITH INTERNALIZING DISORDERS - A REVIEW AND ANALYSIS T2 - School Psychology Review TI - SELF-CONTROL INTERVENTIONS WITH INTERNALIZING DISORDERS - A REVIEW AND ANALYSIS UR - ://WOS:A1992JD52100005 VL - 21 ID - 2959 ER - TY - JOUR AB - OBJECTIVE: To identify recruitment challenges and elucidate specific strategies that enabled recruitment of seniors for a randomized trial on low back pain comparing the Chronic Disease Self-management Program of the Stanford University to a 6-month wait-list control group. DESIGN: Recruitment for a randomized controlled trial. SETTING: Community-based program offered at 12 locations. PARTICIPANTS: Community-dwelling seniors 60 years and older with chronic low back pain of mechanical origin. METHODS: Passive recruitment strategies included advertisement in local and senior newspapers, in senior e-mail newsletters and listservs, in local community centers and businesses. Active strategies included meeting seniors at health fairs, lectures to the public and organizational meetings, and the help of trusted professionals in the community. RESULTS: A total of 100 white and 20 African American seniors were recruited. The program seemed to have the most appeal to white, middle-class older adults, educated through high school level. Advertisement failed to attract any participants to the program. Successful strategies included interaction with seniors at health fairs and lectures on health care, especially when the program was endorsed by a trusted community professional. CONCLUSION: Generating interest in the self-management program required keen communication skills because the idea of "self-management" was met with a myriad of responses, ranging from disinterest to disbelief. Generating interest also required active participation within the communities. Initial contacts had to be established with trusted professionals, whose endorsement enabled the project managers to present the concept of self-management to the seniors. More complex recruitment strategies were required for this study involving the self-management approach to back pain than for studies involving treatment. AD - Center for Outcomes Studies, Western States Chiropractic College, Portland, OR 97230, USA. AN - 15800508 AU - Groupp, E. AU - Haas, M. AU - Fairweather, A. AU - Ganger, B. AU - Attwood, M. DA - Feb DO - 10.1016/j.jmpt.2005.01.004 DP - NLM ET - 2005/04/01 IS - 2 KW - Aged Chronic Disease Female Humans Low Back Pain/*therapy Male Middle Aged *Patient Selection Randomized Controlled Trials as Topic/*methods *Self Care LA - eng N1 - 1532-6586 Groupp, Elyse Haas, Mitchell Fairweather, Alisa Ganger, Bonnie Attwood, Michael R18 HP10012/PHS HHS/United States Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, P.H.S. United States J Manipulative Physiol Ther. 2005 Feb;28(2):97-102. doi: 10.1016/j.jmpt.2005.01.004. PY - 2005 SN - 0161-4754 SP - 97-102 ST - Recruiting seniors with chronic low back pain for a randomized controlled trial of a self-management program T2 - J Manipulative Physiol Ther TI - Recruiting seniors with chronic low back pain for a randomized controlled trial of a self-management program VL - 28 ID - 3643 ER - TY - JOUR AB - In a prospective study of 36 children who were extremely low birthweight (ELBW: < 1000 g) preterm infants and 36 matched full-term controls, differences were found in somatization at age 4 1/2 years. Only children who had been extremely premature, and thereby experienced prolonged hospitalization and repeated medical intervention in infancy, had clinically high somatization scores on the Personality Inventory for Children. The combination of family relations at age 4 1/2 years, neonatal intensive care experience, poor maternal sensitivity to child cues in mother-child interaction observed at age 3 years, and child avoidance of touch or holding at age 3, predicted somatization scores, prior to school entry. Due to the known higher incidence of actual medical problems among children with a history of extreme prematurity, the high somatization ELBW children were compared with the normal somatization ELBW children. There were no differences in prevalence of actual medical problems between the 2 ELBW groups, and the importance of maternal factors in relation to somatization was confirmed. Child temperament at age 3, but not personality at 4 1/2, was related to somatization. The etiology of recurrent physical complaints of no known medical cause appears to be a multi-dimensional problem. Non-optimal parenting may contribute to the development of inappropriate strategies for coping with common pains of childhood, or of chronic pain patterns, in some children who have experienced prolonged or repeated pain as neonates. AD - Department of Psychology, B.C. Children's Hospital, Vancouver, B.C. V6H 3V4 Canada Department of Paediatrics, University of British Columbia, Vancouver, B.C. V6H3V4 Canada. AN - 8022628 AU - Grunau, R. V. E. AU - Whitfield, M. F. AU - Petrie, J. H. AU - Fryer, L. E. DA - Mar DO - 10.1016/0304-3959(94)90174-0 DP - NLM ET - 1994/03/01 IS - 3 KW - Child, Preschool Education Family Female Humans Infant Infant, Low Birth Weight Infant, Newborn *Infant, Premature Intelligence Tests Male Pain/*psychology Parenting Personality Prospective Studies Regression Analysis Temperament LA - eng N1 - Grunau, Ruth V E Whitfield, Michael F Petrie, Julie H Fryer, Louise E Journal Article Research Support, Non-U.S. Gov't United States Pain. 1994 Mar;56(3):353-359. doi: 10.1016/0304-3959(94)90174-0. PY - 1994 SN - 0304-3959 (Print) 0304-3959 SP - 353-359 ST - Early pain experience, child and family factors, as precursors of somatization: a prospective study of extremely premature and fullterm children T2 - Pain TI - Early pain experience, child and family factors, as precursors of somatization: a prospective study of extremely premature and fullterm children VL - 56 ID - 4073 ER - TY - JOUR AB - Previous studies carried out using the Index of Orthodontic Treatment Need (IOTN) have reported that the Aesthetic Component (AC) has limited use in schoolchildren. The purpose of this study was to estimate whether dental concern expressed by the grade of the AC chosen by subjects is reliable and whether it may be predictive for potential co-operation. Such a correlation would indicate if the AC of the IOTN may help to identify individuals interested in orthodontic treatment who would co-operate well, and consequently who might derive the greatest benefits. The investigation was carried out in north-west Poland among 84 schoolchildren (42 girls and 42 boys) aged 12 years and was based on a questionnaire and clinical examination. The questionnaire contained items relating to the subjective assessment of dental appearance, demand for orthodontic treatment, the influence of the dentition on the general appearance, and any functional disorders (speech, mastication, muscular pain, etc.). Clinical examination was carried out at the schools each time by the same dentist. For statistical analysis chi-square (Yates corrected) and McNemar tests were used. A probability at the 5 per cent level or less (P less than or equal to 0.05) was considered statistically significant. The outcome shows that the AC of the IOTN moderately reflects the subjective perception of dental aesthetics and demand for orthodontic treatment. The results indicate that using professional rating the AC scale does not seem to be more precise or reliable than self-evaluation. The correlation between dental concern and the AC would be higher if the 'no treatment need' category was split into two parts (e.g. 1-2 'no need', 3-4 'slight need') or the 'borderline need' category was moved two grades lower. The AC would then help to identify patients interested in treatment who would potentially be co-operative. AN - WOS:000180587700008 AU - Grzywacz, I. DA - Feb DO - 10.1093/ejo/25.1.57 IS - 1 N1 - Grzywacz, I 1460-2210 PY - 2003 SN - 0141-5387 SP - 57-63 ST - The value of the aesthetic component of the Index of Orthodontic Treatment Need in the assessment of subjective orthodontic treatment need T2 - European Journal of Orthodontics TI - The value of the aesthetic component of the Index of Orthodontic Treatment Need in the assessment of subjective orthodontic treatment need UR - ://WOS:000180587700008 VL - 25 ID - 2813 ER - TY - JOUR AB - Over the past 50 years it has become clear that physical inactivity is associated with chronic disease risk. For several rheumatic diseases, bed rest was traditionally advocated as the best treatment, but several levels of evidence support the imminent paradigm shift from the prescription of bed rest to physical activity in individuals with paediatric rheumatic diseases, in particular juvenile systemic lupus erythematosus, juvenile idiopathic arthritis, juvenile fibromyalgia, and juvenile dermatomyositis. Increasing levels of physical activity can alleviate several symptoms experienced by patients with paediatric rheumatic diseases, such as low aerobic fitness, pain, fatigue, muscle weakness and poor health-related quality of life. Moreover, the propensity of patients with paediatric rheumatic diseases to be hypoactive-often due to social self-isolation, overprotection, and fear and/or ignorance on the part of parents, teachers and health practitioners - can be detrimental to general disease symptoms and function. In support of this rationale, a growing number of studies have demonstrated that the systemic benefits of exercise training clearly outweigh the risks in these diseases. In this sense, health professionals are advised to assess, track and fight against physical inactivity and sedentary behaviour on a routine basis, as they are invaluable health risk parameters in rheumatology. AN - WOS:000401720700008 AU - Gualano, B. AU - Bonfa, E. AU - Pereira, R. M. R. AU - Silva, C. A. DA - Jun DO - 10.1038/nrrheum.2017.75 IS - 6 N1 - Gualano, Bruno Bonfa, Eloisa Pereira, Rosa M. R. Silva, Clovis A. Silva, Clovis/J-3640-2017; Pereira, Rosa M R/C-5192-2012; Gualano, Bruno/C-7190-2012; Gualano, Bruno/ABA-9571-2020; Bonfa, Eloisa/B-8438-2012; Sampaio, Magda/AAU-6748-2020 Pereira, Rosa M R/0000-0002-3723-5028; Gualano, Bruno/0000-0001-7100-8681; Gualano, Bruno/0000-0001-7100-8681; Bonfa, Eloisa/0000-0002-0520-4681; Sampaio, Magda/0000-0002-1924-4043 1759-4804 PY - 2017 SN - 1759-4790 SP - 368-379 ST - Physical activity for paediatric rheumatic diseases: standing up against old paradigms T2 - Nature Reviews Rheumatology TI - Physical activity for paediatric rheumatic diseases: standing up against old paradigms UR - ://WOS:000401720700008 VL - 13 ID - 2097 ER - TY - JOUR AB - There is ample empirical evidence supporting the view of emotional disturbances in children with recurrent abdominal pain (RAP) as well as in their parents. However, controlled studies have reported that such manifestations can also be found in patients with other chronic ailments. In order to characterize further the nature of emotional factors in RAP patients, we conducted a controlled psychological evaluation of 46 consecutive new patients with RAP, aged 7-17 years, (group A) by means of structured interviews and questionnaires. Two control groups of pediatric patients with chronic illnesses were also assessed using the same methodology. Group B consisted of 22 individuals with chronic abdominal pain and endoscopy-proven peptic ulcer or duodenitis, and group C consisted of 24 individuals with chronic, stable, non-gastroenterological diseases (e.g., diabetes mellitus or physical handicaps). Parents were evaluated for depressive symptoms. One-way analysis of variance and contingency tables were used for statistical comparisons. There was a higher proportion of female patients in group A than in group B (70 vs 41%; p<0.05). There were significantly more patients in group A than in group B that reported that their abdominal pain: a) never appeared during sleep, b) began soon after the patient's arousal in the morning, c) remitted completely or was alleviated during school holidays, d) its remission was usually spontaneous during the day and e) did never interfere with recreational activities. Emotional problems were significantly more prevalent in patients in group B than in those in group A (p = 0.016). Past diagnosis of depression was more frequent in group A mothers (40%) than in those group B (27%), or group C (17%), but these differences did not attain statistical significance. These results suggest that psychological profiles of children suffering from certain chronic conditions (and those of their parents) may be more complex and particular than hitherto recognized. The role of type II error and of some potential socioeconomic and demographic confounding factors must be considered when analyzing the validity of these data. AN - WOS:A1995TR05700002 AU - Guiraldes, E. AU - Carrasco, E. AU - Olivari, C. AU - Cerfogli, C. AU - Trivino, X. AU - Parada, H. AU - Pena, A. DA - Nov IS - 11 N1 - Guiraldes, E Carrasco, E Olivari, C Cerfogli, C Trivino, X Parada, H Pena, A PY - 1995 SN - 0034-9887 SP - 1341-1348 ST - Clinical and psychological characterization of children with recurrent abdominal pain T2 - Revista Medica De Chile TI - Clinical and psychological characterization of children with recurrent abdominal pain UR - ://WOS:A1995TR05700002 VL - 123 ID - 2932 ER - TY - JOUR AB - The focus of this brief review is to highlight to the reader some of the 'ripple effects' of broader systems-level healthcare issues and the implications they may have for effective treatment of pediatric chronic pain. Many healthcare providers focus almost exclusively on the patient, but lack the knowledge of how to intervene effectively at systems levels with families, schools and healthcare institutions surrounding the pediatric patient with pain. We provide a case example and consider this issue across three systems that are particularly relevant to pediatric pain management: the outpatient pain clinic, school and inpatient settings. The information presented will improve the healthcare provider's ability to effectively treat pediatric pain through an enhanced understanding of the multiple s-ystems of care that surround children with pain. AN - WOS:000219013200014 AU - Guite, J. W. AU - Logan, D. E. AU - Ely, E. A. AU - Weisman, S. J. DA - Nov DO - 10.2217/pmt.12.63 IS - 6 N1 - Guite, Jessica W. Logan, Deirdre E. Ely, Elizabeth A. Weisman, Steven J. 1758-1877 PY - 2012 SN - 1758-1869 SP - 593-601 ST - The ripple effect: systems-level interventions to ameliorate pediatric pain T2 - Pain Management TI - The ripple effect: systems-level interventions to ameliorate pediatric pain UR - ://WOS:000219013200014 VL - 2 ID - 2413 ER - TY - JOUR AB - Objectives: Children learn to cope with pain within the context of the family and parental responses to pediatric pain can impact health outcomes. The aim of this study was to examine relationships among pain, protective parental responses to pain, functional disability, and pain catastrophizing for adolescents with chronic musculoskeletal pain syndromes. Methods: Initial evaluation records for 138 adolescents with chronic musculoskeletal pain who consulted a pediatric multidisciplinary pain management clinic were examined. Measures were collected at the time of the initial evaluation and included adolescent self-reports of their own usual pain intensity, perceived parental responses to their pain, adolescent functional disability, and pain catastrophizing. Results: Pain catastrophizing was significantly correlated with pain intensity, protective parental responses to pain, and functional disability. Multiple regression analyses further suggest that pain catastrophizing serves as a mediator of relationships between: (1) pain and disability and (2) protective parenting responses and disability. Evidence supporting a significant indirect effect for pain catastrophizing on disability was found within both models through bootstrap and Sobel analyses. Discussion: Pain catastrophizing seems to play an important role in understanding relationships between pain, protective parental responses, and disability for adolescents with musculoskeletal pain. Our findings suggest that strategies that help modify adolescent catastrophic pain beliefs and parental responses to pain, may help improve adolescent functioning. AN - WOS:000295846200005 AU - Guite, J. W. AU - McCue, R. L. AU - Sherker, J. L. AU - Sherry, D. D. AU - Rose, J. B. DA - Nov-Dec DO - 10.1097/AJP.0b013e31821d8fb4 IS - 9 N1 - Guite, Jessica W. McCue, Rebecca L. Sherker, Jennifer L. Sherry, David D. Rose, John B. Guite, Jessica/AAP-9947-2021 Guite, Jessica/0000-0003-1038-3386 1536-5409 PY - 2011 SN - 0749-8047 SP - 775-781 ST - Relationships Among Pain, Protective Parental Responses, and Disability for Adolescents With Chronic Musculoskeletal Pain The Mediating Role of Pain Catastrophizing T2 - Clinical Journal of Pain TI - Relationships Among Pain, Protective Parental Responses, and Disability for Adolescents With Chronic Musculoskeletal Pain The Mediating Role of Pain Catastrophizing UR - ://WOS:000295846200005 VL - 27 ID - 2474 ER - TY - JOUR AB - Parents of youth with chronic health conditions encounter numerous challenges in supporting their children across pediatric treatment contexts. Structural barriers to care, such as access issues and coordinating care across school, health, and family settings, can exacerbate challenges to daily functioning. Parents are often concomitantly managing their child's chronic condition, their own health care needs, work and family demands. For these parents, accomplishing a manageable "work-life balance" feels elusive, if not impossible, when a chronic health condition is part of family life. Based on a recent symposium presentation, combined perspectives from the disciplines of pediatric psychology, parenting, and human development and family studies consider key challenges and opportunities to assist parent coping with stress associated with caregiving amidst pervasive changes in healthcare service delivery. Two innovative interventions to support parents in both an outpatient ("Parents as Coping Coaches") and an inpatient ("Putting Parents FIRST") context are described, with commonalities and unique aspects highlighted for each. These programs are considered in reference to a rapidly changing healthcare landscape, growing focus on the family as a core context for care, and importance of parent/caregiver self-care and crucial role in supporting children's long-term health and resiliency. AN - WOS:000454708100006 AU - Guite, J. W. AU - Russell, B. S. AU - Homan, K. J. AU - Tepe, R. M. AU - Williams, S. E. C7 - 161 DA - Dec DO - 10.3390/children5120161 IS - 12 N1 - Guite, Jessica W. Russell, Beth S. Homan, Kendra J. Tepe, Rebecca M. Williams, Sara E. Guite, Jessica/AAP-9947-2021 Guite, Jessica/0000-0003-1038-3386; Homan, Kendra/0000-0001-8478-3628 2227-9067 PY - 2018 ST - Parenting in the Context of Children's Chronic Pain: Balancing Care and Burden T2 - Children-Basel TI - Parenting in the Context of Children's Chronic Pain: Balancing Care and Burden UR - ://WOS:000454708100006 VL - 5 ID - 1978 ER - TY - JOUR AB - Migraine is an episodic disease characterized by a throbbing and generally unilateral headache, often accompanied by nausea, vomiting and light and sound sensitivity. Migraine is known to affect one's quality of life; not only the person with migraine but also his/her family and social environment are affected by this condition. Our study aimed to evaluate the effects of maternal migraine on children's quality of life. The patient group comprised 70 mothers with migraine diagnoses and their 111 healthy children, while 50 healthy mothers and their 86 children were included in this study as the control group. The Visual Analog Scale (VAS), Migraine Disability Assessment Scale, Beck Depression Index (BDI) and Beck Anxiety Index (BAI) were used for evaluation of mothers; 3 to 7-year old KINDL and 7- to 17-year-old KINDL-R Quality of Life Scales were used to evaluate the quality of life of children. The SPSS 21.0 program was used for statistical analysis and p < 0.05 was assumed to be statistically significant. The mean age of the migraine group was 37.09 +/- 6.94 years, and the mean age of the control group was 38.2 +/- 4.5. Symptoms of depression and anxiety were more frequently found in subjects with migraine (p < 0.05). In comparison with the control group: 3 to 7-year old KINDL total scores, self-esteem and school subscales, 7- to 17-year-old KINDL total scores, self-esteem and the social relationships subscale scores were lower in migraine group. It was found to be significant that VAS, BDI and BAI scores of the mothers were negatively correlated with the children's quality of life. Our study concluded that the presence of migraine-type headache in mothers worsen the relations in school, self-esteem and quality of life in younger children and social relations, relations in school and quality of life in older children. The maternal age, disease severity, and anxiety and depression symptoms were shown to predict the quality of life in children. Performing preventive interventions by individually assessing bio-psycho-social elements for the treatment of mothers with migraine will preserve other family member's and especially children's quality of life. AN - WOS:000408089700013 AU - Gungen, B. D. AU - Aras, Y. G. AU - Gul, S. S. AU - Acar, T. AU - Ayaz, A. B. AU - Alagoz, A. N. AU - Acar, B. A. DA - Sep DO - 10.1007/s13760-017-0790-y IS - 3 N1 - Gungen, Belma Dogan Aras, Yesim Guzey Gul, Sidika Sinem Acar, Turkan Ayaz, Ayse Burcu Alagoz, Aybala Neslihan Acar, Bilgehan Atilgan Acar, Bilgehan/J-8931-2019; GUNGEN, BELMA DOGAN/AAO-2472-2020 2240-2993 PY - 2017 SN - 0300-9009 SP - 687-694 ST - The effect of maternal migraine headache on their children's quality of life T2 - Acta Neurologica Belgica TI - The effect of maternal migraine headache on their children's quality of life UR - ://WOS:000408089700013 VL - 117 ID - 2077 ER - TY - JOUR AB - A study was undertaken to analyse the prevalence of low back pain (LBP) and confounding factors in primary school children in the city of Antwerp. A total of 392 children aged 9 were included in the study. All children completed a validated three-page questionnaire and they all underwent a specific lumbar spine oriented medical examination during their annual routine medical school control. This examination was performed by the city school doctors. The questionnaire was composed of easy "yes/no" questions and visual analogue scales. Statistical analysis was performed using Student's t-test and chi-squared test at the significance level P < 0.05. The prevalence of LBP was high. No gender difference was found. A total of 142 children (36%) reported having suffered at least one episode of LBP in their lives. Of these, 33 (23%) had sought medical help for LBP from a doctor or physiotherapist. Sixty-four percent of children reporting LBP said that at least one of their parents suffered from or complained of LBP. This was significantly higher than for the children who did not report having suffered LBP. The way in which the school satchel was carried (in the hand, on the back) had no bearing on the incidence of LBP. There was significantly more LBP in children who reported playing video games for more than 2 h per day, but this was not so for television watchers. The visual analogue scales concerning general well-being were all very significantly correlated with self-reported LBP, with children who reported LBP being more tired, less happy, and worse sleepers. Of the 19 clinical parameters taken down during the medical examination, only one was significantly more prevalent in the group of children reporting LBP: pain on palpation at the insertion site on the iliac crest of the ilio-lumbar ligament. From this study we can establish that there are few clinical signs that can help to single out school children with LBP. AU - Gunzburg, R. AU - Balagué, F. AU - Nordin, M. AU - Szpalski, M. AU - Duyck, D. AU - Bull, D. AU - Mélot, C. DA - 1999 DO - 10.1007/s005860050202 DP - PubMed IS - 6 J2 - Eur Spine J KW - Child Cross-Sectional Studies Female Humans Intervertebral Disc Displacement Life Style Low Back Pain Lumbar Vertebrae Male Prevalence LA - eng PY - 1999 SN - 0940-6719 SP - 439-443 ST - Low back pain in a population of school children T2 - European Spine Journal: Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society TI - Low back pain in a population of school children UR - http://www.ncbi.nlm.nih.gov/pubmed/10664300 VL - 8 ID - 121 ER - TY - JOUR AB - Objective Symptoms of endometriosis, including pelvic pain, back and nerve pain, and gastrointestinal pain, often begin in adolescence. Yet, research on the experience of these debilitating symptoms among young people is scarce. Of particular concern is the influence of adolescent girls' social context. This study qualitatively examined how, among adolescents, endometriosis and symptoms suggestive of endometriosis is perceived at the family, peer/school and community/society levels. Design Eight focus groups were conducted; vignettes were used to elicit participants' perceptions of factors that may shape girls' experiences of endometriosis. Data were analysed using constant comparison analysis. Participants An ethnically diverse sample of girls and boys ages 14-18 (n=54) residing in New York City. Results Fifteen themes emerged and were distilled to eight cross-cutting factors that influence perceptions of endometriosis at different levels of the ecological model: distrust of community healthcare providers, societal stigma of menstruation, peer stigma of endometriosis symptoms, distrust of school healthcare providers, lack of endometriosis knowledge among peers and school personnel, inequitable gender norms, invisibility of symptoms and the stigma of teen sex among parents. Further, these factors may compound symptoms' impact on individual girl's social, educational and emotional well-being. Conclusions Findings underscore the importance of understanding the social environment of girls experiencing symptoms suggestive of endometriosis and educating and engaging their peers, family and school personnel to create a supportive, informed social climate. Efforts should specifically include stigma reduction campaigns targeted towards female and male adolescents. AN - WOS:000435567900052 AU - Gupta, J. AU - Cardoso, L. F. AU - Harris, C. S. AU - Dance, A. D. AU - Seckin, T. AU - Baker, N. AU - Ferguson, Y. O. C7 - e020657 DA - Jun DO - 10.1136/bmjopen-2017-020657 IS - 6 N1 - Gupta, Jhumka Cardoso, Lauren F. Harris, Courtney S. Dance, Arielle D. Seckin, Tamer Baker, Nina Ferguson, Yvonne O. PY - 2018 SN - 2044-6055 ST - How do adolescent girls and boys perceive symptoms suggestive of endometriosis among their peers? Findings from focus group discussions in New York City T2 - Bmj Open TI - How do adolescent girls and boys perceive symptoms suggestive of endometriosis among their peers? Findings from focus group discussions in New York City UR - ://WOS:000435567900052 VL - 8 ID - 2013 ER - TY - JOUR AB - Objective: The present study aims to determine the frequency and characteristics of migraine and tension-type headache (TTH) in children and adolescents aged 10 to 18, and to evaluate the findings accompanying the headache and the factors increasing it. Methods: Of 2576 students in total aged 10 to 18 from 17 schools in downtown Semdinli and the villages of the county of Semdinli 1614 students who filled out the questionnaire properly were included in the study and the characteristics of headaches were analyzed based on the International Classification of Headache Disorders (ICHD-3 beta) diagnostic criteria and the visual pain scale. Results: One thousand four hundred and eighty three of the students expressed they had experienced headache at least once in their life, and 54.6% of these were female students. In the questionnaire, the headache was most frequently accompanied by sensitivity to sound, and the most frequent trigger was sound again. The most prevalent answer for the frequency of headache was '1 to 3 headache attacks a week' in all age groups. 94 students were diagnosed with migraine while 548 were diagnosed with TTH. Conclusion: This questionnaire-based study found the prevalence of migraine as 6.3% and the prevalence of TTH as 40.1%, and revealed that headache was most prevalent in the age group of 10-12 and more common in females than in males. The present study aims to raise awareness among physicians and patients so that headaches will be diagnosed early which in turn will increase the quality of life and academic success of the patients. AN - WOS:000484316100005 AU - Gursoy, G. AU - Bayir, B. R. H. AU - Icil, S. DA - Sep DO - 10.5152/nsn.2019.11978 IS - 3 N1 - Gursoy, Gizem Bayir, Buse Rahime Hasirci Icil, Suzan 54th National Neurology Congress Dec 04, 2018 Antalya, TURKEY PY - 2019 SN - 2636-865X SP - 152-157 ST - Migraine and tension-type headache in children and adolescents a prospective cohort study T2 - Neurological Sciences and Neurophysiology TI - Migraine and tension-type headache in children and adolescents a prospective cohort study UR - ://WOS:000484316100005 VL - 36 ID - 1887 ER - TY - JOUR AB - Background and aims: Chronic and recurrent pain is prevalent in adolescents and generally girls report more pain symptoms than boys. Also, pain symptoms and sleep problems often co-occur. Pain symptoms have negative effects on school achievement, emotional well-being, sleep, and overall health and well-being. For effective intervention and prevention there is a need for defining factors associated with pain symptoms and daytime sleepiness. The aim of this longitudinal study was to investigate the prevalence and association between neck-shoulder pain, back pain, psychological symptoms and daytime sleepiness in 10-, 12- and 15-year-old children. This study is the first that followed up the same cohort of children from the age of 10 to 15. Methods: A cohort study design with three measurement points was used. Participants (n = 568) were recruited from an elementary school cohort in a city of 1,75,000 inhabitants in South-Western Finland. Symptoms and daytime sleepiness were measured with self-administered questionnaires. Regression models were used to analyze the associations. Results: Frequent neck-shoulder pain and back pain, and psychological symptoms, as well as daytime sleepiness, are already common at the age of 10 and increase strongly between the ages 12 and 15. Overall a greater proportion of girls suffered from pain symptoms and daytime sleepiness compared to boys. Daytime sleepiness in all ages associated positively with the frequency of neck-shoulder pain and back pain. The more that daytime sleepiness existed, the more neck-shoulder pain and back pain occurred. Daytime sleepiness at the age of 10 predicted neck-shoulder pain at the age of 15, and back pain at the age of 10 indicated that there would also be back pain at the age of 15. In addition, positive associations between psychological symptoms and neck-shoulder pain, as well as back pain, were observed. Subjects with psychological problems suffered neck-shoulder pain and back pain more frequently. Conclusions: This study is the first study that has followed up the same cohort of children from the age of 10 to 15. The studied symptoms were all already frequent at the age of 10. An increase mostly happened between the ages of 12 and 15. Moreover, the self-reported daytime sleepiness at the age of 10 predicted neck-shoulder pain at the age of 15. More attention should be paid to the daytime sleepiness of children at an early stage as it has a predictive value for other symptoms later in life. Implications: School nurses, teachers and parents are in a key position to prevent adolescents' sleep habits and healthy living habits. Furthermore, the finding that daytime sleepiness predicts neck-shoulder pain later in adolescence suggests that persistent sleep problems in childhood need early identification and treatment. Health care professionals also need take account of other risk factors, such as psychological symptoms and pain symptoms. The early identification and treatment of sleep problems in children might prevent the symptoms' development later in life. There is a need for an individuals' interventions to treat adolescents' sleep problems. AN - WOS:000439314200009 AU - Gustafsson, M. L. AU - Laaksonen, C. AU - Aromaa, M. AU - Loyttyniemi, E. AU - Salantera, S. DA - Jul DO - 10.1515/sjpain-2017-0166 IS - 3 N1 - Gustafsson, Marja-Liisa Laaksonen, Camilla Aromaa, Minna Loyttyniemi, Eliisa Salantera, Sanna Salantera, Sanna/0000-0003-2529-6699 1877-8879 PY - 2018 SN - 1877-8860 SP - 389-397 ST - The prevalence of neck-shoulder pain, back pain and psychological symptoms in association with daytime sleepiness - a prospective follow-up study of school children aged 10 to 15 T2 - Scandinavian Journal of Pain TI - The prevalence of neck-shoulder pain, back pain and psychological symptoms in association with daytime sleepiness - a prospective follow-up study of school children aged 10 to 15 UR - ://WOS:000439314200009 VL - 18 ID - 2007 ER - TY - JOUR AB - Background and Study Aims: In various gastrointestinal system diseases, emotional dysregulation has been shown to reduce pain tolerance and increase the severity of the disease. Increased emotional dysregulation during the adolescence period causes gastrointestinal symptoms to be more frequent and severe. In this study, Child Depression Inventory (CDI) scores were investigated in patients admitted to our clinic with functional gastrointestinal disorders. Patients and Methods: According to Rome IV criteria, 200 patients with functional abdominal pain and dyspepsia aged 12-17 years were included in this study. 100 patients without a chronic disease were taken as control group. Patients completed the self-report questionnaires about symptoms, school performance, nutrition and sports habits. We used Child Depression Inventory (CDI) to assess the patients' depression. Results: The mean age of study group was 15.29 +/- 1.48 years (12-17 years), median 16 years; 80% (160/200) were girls. The mean age of control group was 14.96 +/- 1.66 years (12-17 years), median 15 years; 70% (70/100) were girls. There is no difference between the two groups for age and gender. Median depression score was 12.5 (range, 0-53) in the study group and 10.0 (range, 0-41) in the control group and a significant difference was found between the two groups (p = 0.014). School performance was revealed as 'very good' in 112 (56%) children in the study group and in 24 (24%) children in the control group and a significant difference was found between the two groups (p < 0.001). A negative correlation was found between school performance and depressive symptoms. Conclusion: It is not clear that emotional dysregulation induces FGIDs or FGIDs cause emotional dysregulation. But it is known that these diseases are common in the adolescent age group. Incorporating social and physical activities into the educational processes of adolescents will have favorable effects on their academic performance as well as emotional regulation. (C) 2020 Pan-Arab Association of Gastroenterology. Published by Elsevier B.V. All rights reserved. AN - WOS:000529355200005 AU - Guven, B. AU - Gulerman, F. AU - Akyuz, E. AU - Aydin, G. DA - Mar DO - 10.1016/j.ajg.2020.02.002 IS - 1 N1 - Guven, Burcu Gulerman, Fulya Akyuz, Ebubekir Aydin, Gozde Gulerman, Hacer Fulya/AAD-2287-2021 2090-2387 PY - 2020 SN - 1687-1979 SP - 24-27 ST - Emotional dysregulation in adolescents with functional gastrointestinal disorders T2 - Arab Journal of Gastroenterology TI - Emotional dysregulation in adolescents with functional gastrointestinal disorders UR - ://WOS:000529355200005 VL - 21 ID - 1836 ER - TY - JOUR AB - Objective: To evaluate the role of food habits and nutrient intake in children with functional gastrointestinal disorders (FGIDs) considering their association with psychosocial factors. Design: Cross-sectional. Setting: A rural town in Mid-Western Finland. Subjects: After excluding organic gastrointestinal (GI) disorders, a total of 49 children with FGID and 78 control children without GI symptoms from a cohort of 422 children were studied. Methods: Food frequency questionnaire, GI-symptoms questionnaire and the Child Behaviour Check List (CBCL) filled in by parents together with their child, and 24-h dietary recall and anthropometric and haematological measurements. Results: Compared to control children, fewer children with FGID had daily family dinner (77 vs 91%, P = 0.030) and they used less often vegetables (P = 0.023), fruits (P = 0.027) and berries (P = 0.011), but more often ice cream (P = 0.018) and soft drinks (P = 0.027) and had a higher sucrose intake (9 vs 7E%, P = 0.032) and lower lactose intake (27 vs 36 g, P = 0.001). Reported food-related symptoms were more common among FGID group (69 vs 11%), as well as restricted milk use (31 vs 0%). Children with FGID had higher total problem scores in CBCL (P = 0.002), and the behavioural/emotional problems associated with occurrence of FGID (OR 1.04, 95% CI 1.07-1.076) as did the sugar intake (OR 1.1, 95% CI 1.004-1.215). Conclusions: This population-based study suggests that school-aged children with FGIDs have less-organized food habits and higher milk avoidance, and they display internalizing psychological characteristics. AN - WOS:000222274800006 AU - Haapalahti, M. AU - Mykkanen, H. AU - Tikkanen, S. AU - Kokkonen, J. DA - Jul DO - 10.1038/sj.ejcn.1601925 IS - 7 N1 - Haapalahti, M Mykkanen, H Tikkanen, S Kokkonen, J Hyytinen, Mila Maarit/0000-0001-5361-6421 1476-5640 PY - 2004 SN - 0954-3007 SP - 1016-1021 ST - Food habits in 10-11-year-old children with functional gastrointestinal disorders T2 - European Journal of Clinical Nutrition TI - Food habits in 10-11-year-old children with functional gastrointestinal disorders UR - ://WOS:000222274800006 VL - 58 ID - 2789 ER - TY - JOUR AB - AIM: To investigate associations between negative life experiences and common illnesses among adolescents. METHODS: Cross-sectional questionnaire study carried out at all lower secondary schools (10 grade) in Oslo. Norway, during 2000 and 2001 (n = 8316 pupils). Different negative life experiences and illnesses were addressed. RESULTS: The participation rate was 88%. Among reported negative life experiences last year were a pressure felt to succeed (62%), death of a close person (26%), exposure to physical violence (22%), bullying at school (15%) and sexual violation (4%). A large number of the pupils had some chronic illness: hay fever (38%), eczema (29%) and asthma (13%). Reported illnesses the previous 12 month were: headache (56%), painful neck or shoulders (35%), sore throat at least three times (15%), lower respiratory tract infection (9%) and mental problems for which help was sought (7%). During the week prior to the survey, 26% of all girls had symptoms of a depressive disorder, while this applied to 10% of all boys. Fifty-three percent of the boys (29% of the girls) who had depressive symptoms had been exposed to physical violence. Sexually violated boys had a high probability for seeking help for mental problems (OR = 4.9) and for frequent episodes of sore throat (OR = 2.5). Corresponding odds ratios for girls were 1.7 and 2.5, respectively. CONCLUSION: Common illnesses in adolescence are significantly associated with negative life experiences. In clinical encounters with adolescents not only should the presenting complaints be addressed, but also other common illnesses and relevant background factors such as negative life events. AD - Department of General Practice and Community Medicine, Section for General Practice, University of Oslo, Oslo, Norway. o.r.haavet@samfunnsmed.uio.no AN - 15124848 AU - Haavet, O. R. AU - Straand, J. AU - Saugstad, O. D. AU - Grünfeld, B. DA - Mar DP - NLM ET - 2004/05/06 IS - 3 KW - Adolescent Chronic Disease/*epidemiology Cross-Sectional Studies Depression/*epidemiology Headache/epidemiology Health Status Indicators Humans *Life Change Events Norway Pharyngitis/epidemiology Violence/statistics & numerical data LA - eng N1 - Haavet, O R Straand, J Saugstad, O D Grünfeld, B Journal Article Research Support, Non-U.S. Gov't Norway Acta Paediatr. 2004 Mar;93(3):405-11. PY - 2004 SN - 0803-5253 (Print) 0803-5253 SP - 405-11 ST - Illness and exposure to negative life experiences in adolescence: two sides of the same coin? A study of 15-year-olds in Oslo, Norway T2 - Acta Paediatr TI - Illness and exposure to negative life experiences in adolescence: two sides of the same coin? A study of 15-year-olds in Oslo, Norway VL - 93 ID - 3293 ER - TY - JOUR AB - Objective The aim of the present study was to describe handwriting difficulties of primary school children with juvenile idiopathic arthritis (JIA), and to investigate possible correlations with hand function and writing performance. Methods In a cross-sectional approach, 15 children with JIA and reported handwriting difficulties were included together with 15 healthy matched controls. Impairments (signs of arthritis or tenosynovitis, reduced grip force and limited range of motion of the wrist (wrist-ROM)), activity limitations (reduced quality and speed of handwriting, pain during handwriting), and participation restrictions (perceived handwriting difficulties at school) were assessed and analysed. Results Although selected by the presence of handwriting difficulties, the majority oldie JIA children (73%) had no active arthritis of the writing hand, and only minor hand impairments were found. Overall, the JIA children performed well during the short handwriting test, but the number of letters they wrote per minute decreased significantly during the 5-minute lest, compared to the healthy controls. JIA patients had significantly higher pain scores on a 100 nun Visual Analogue Scale, compared to the healthy controls. The actual presence of arthritis, and limitation in grip force and wrist-ROM did not correlate with reported participation restrictions with regard to handwriting at school. The JIA children reported pain during handwriting, and inability to sustain handwriting for a longer period of time. Conclusions The results of this pilot study show that JIA children with handwriting difficulties, experience their restrictions mainly through pain and the inability to sustain handwriting for a longer period of time. No correlations could be found with impairments. AN - WOS:000297192600023 AU - Haberfehlner, H. AU - Visser, B. AU - Daffertshofer, A. AU - van Rossum, M. A. J. AU - Roorda, L. D. AU - van der Leeden, M. AU - Dekker, J. AU - Hoeksma, A. F. DA - Sep-Oct IS - 5 N1 - Haberfehlner, H. Visser, B. Daffertshofer, A. van Rossum, M. A. J. Roorda, L. D. van der Leeden, M. Dekker, J. Hoeksma, A. F. Visser, Bart/K-7883-2013 Visser, Bart/0000-0002-8559-9715; Dekker, Joost/0000-0003-2027-0027; Haberfehlner, Helga/0000-0001-9307-4102; Daffertshofer, Andreas/0000-0001-9107-3552 PY - 2011 SN - 0392-856X SP - 887-893 ST - Handwriting difficulties in juvenile idiopathic arthritis: a pilot study T2 - Clinical and Experimental Rheumatology TI - Handwriting difficulties in juvenile idiopathic arthritis: a pilot study UR - ://WOS:000297192600023 VL - 29 ID - 2477 ER - TY - JOUR AB - juvenile fibromyalgia is a chronic pain syndrome, which predominantly occurs in girls around puberty. Its frequency is increasing. Presently, it affects about 10% of patients in pediatric rheumatology centers. It exposes itself as widespread musculoskeletal pain and is almost always associated with vegetative symptoms. The complaints increase during the course of the disease and lead to social isolation. The children have long absenteeism from school, give up leisure activities, and avoid contacts with their peer group, with detrimental affects and a resultant vicious circle of increasing pain. The differentiation from rheumatoid diseases is not always straightforward, especially since secondary pain syndromes can develop in children with rheumatoid disease. AN - WOS:000222664400005 AU - Hafner, R. DA - Jun DO - 10.1055/s-2004-813307 IS - 3 N1 - Hafner, R 1438-9940 PY - 2004 SN - 0341-051X SP - 142-143 ST - Juvenile fibromyalgia - "Everything hurts" T2 - Aktuelle Rheumatologie TI - Juvenile fibromyalgia - "Everything hurts" UR - ://WOS:000222664400005 VL - 29 ID - 2792 ER - TY - JOUR AB - Chronic childhood arthritis impairs joint function and may result in severe physical handicap. Joint pain and inflammation trigger a vicious cycle that often ends in joint damage and fixed deformities. A comprehensive rehabilitation programme must start early to restore loss of function and prevent permanent handicap. It is dominated by a physiotherapeutic regimen consisting of pain relief, movement expansion, training of muscular coordination and finally re-integration of a physiological movement pattern. The approaches of occupational therapy become integrated into the treatment programme, concentrating on joint protection and self-care training. Additional aids support the aim of joint restoration. They include individual splinting, adapted footwear and walking aids. Depending on the child's age and developmental status different aspects of rehabilitation dominate. Small children need adequate mobility to promote their psychosocial development. In later years integration into school life and the peer group becomes important. Adolescents require help for an adequate vocational training and self-care support. Last but not least, parental education and integration of the whole family into the rehabilitation programme markedly improve the patient's prognosis. AN - WOS:000076510800011 AU - Hafner, R. AU - Truckenbrodt, H. AU - Spamer, M. DA - May DO - 10.1016/s0950-3579(98)80022-8 IS - 2 N1 - Hafner, R Truckenbrodt, H Spamer, M PY - 1998 SN - 0950-3579 SP - 329-361 ST - Rehabilitation in children with juvenile chronic arthritis T2 - Baillieres Clinical Rheumatology TI - Rehabilitation in children with juvenile chronic arthritis UR - ://WOS:000076510800011 VL - 12 ID - 2897 ER - TY - JOUR AB - OBJECTIVE: Family resources and coping skills are important to adaptation to pediatric chronic illness. Psychological and educational interventions have been found to enhance the coping skills of children with juvenile rheumatic disease (JRD) and their families. We examined the efficacy of a 3-day family retreat as a multidisciplinary, comprehensive treatment. METHODS: Children with JRD and their caregivers completed questionnaires assessing the children's behavioral and emotional functioning, pain, strain on caregivers' work and leisure activities, and caregivers' psychological distress before and 6 months after the family retreat. Principal caregivers were both parents for 16 children, mothers only for 10 children, and an aunt for 1 child. RESULTS: Improvements were found in children's emotional functioning, strain on caregivers' work, and strain on caregivers' leisure activities. Reductions in reported pain were not consistently revealed. CONCLUSIONS: Family retreats are an efficacious, multidisciplinary approach to helping families of children with JRD cope with the disease and its manifestations. Importantly, retreats offer a comprehensive intervention package that might not be available to families on an individual basis. AU - Hagglund, K. J. AU - Doyle, N. M. AU - Clay, D. L. AU - Frank, R. G. AU - Johnson, J. C. AU - Pressly, T. A. DA - 1996/02// DO - 10.1002/art.1790090108 DP - PubMed IS - 1 J2 - Arthritis Care Res KW - Adaptation, Psychological Adolescent Adult Arthritis, Juvenile Caregivers Child Child, Preschool Comprehensive Health Care Family Female Humans Male Middle Aged Patient Care Team Patient Education as Topic Program Evaluation Surveys and Questionnaires LA - eng PY - 1996 SN - 0893-7524 SP - 35-41 ST - A family retreat as a comprehensive intervention for children with arthritis and their families T2 - Arthritis Care and Research: The Official Journal of the Arthritis Health Professions Association TI - A family retreat as a comprehensive intervention for children with arthritis and their families UR - http://www.ncbi.nlm.nih.gov/pubmed/8945111 VL - 9 ID - 1 ER - TY - JOUR AB - AIM: To document objective sleep patterns of children and adolescents with functional recurrent abdominal pain (RAP), and to compare them with subjective sleep assessments and sleep patterns of healthy controls. METHODS: Subjective sleep reports and sleep habit assessments were obtained from 25 adolescents with functional RAP and from 15 age- and gender-matched healthy volunteers, and were compared with continuous movement monitoring using the Actigraph for 7 consecutive days. RESULTS: Abdominal pain before falling asleep was a unanimous complaint in the RAP group, with 29% reporting awakening from sleep by the pain. Only 25% of RAP patients assessed their sleep quality as good, compared with 87% of the control group. Objective sleep patterns measurements of the RAP patients were similar to those of the control group as well as to measurements observed in a large population of school-aged children and adolescents. CONCLUSION: This study of a small group of children and adolescents with functional RAP provides objective evidence that their sleep patterns do not differ from those of normal peers, despite their subjective complaints. AD - The Bruce Rappaport School of Medicine, Technion-Israel Institute of Technology, Haifa, Israel. AN - 15174794 AU - Haim, A. AU - Pillar, G. AU - Pecht, A. AU - Lerner, A. AU - Tov, N. AU - Jaffe, M. AU - Hardoff, D. DA - May DP - NLM ET - 2004/06/04 IS - 5 KW - Abdominal Pain/*physiopathology Adolescent Child Humans Recurrence Sleep/*physiology LA - eng N1 - Haim, A Pillar, G Pecht, A Lerner, A Tov, N Jaffe, M Hardoff, D Comparative Study Journal Article Norway Acta Paediatr. 2004 May;93(5):677-80. PY - 2004 SN - 0803-5253 (Print) 0803-5253 SP - 677-80 ST - Sleep patterns in children and adolescents with functional recurrent abdominal pain: objective versus subjective assessment T2 - Acta Paediatr TI - Sleep patterns in children and adolescents with functional recurrent abdominal pain: objective versus subjective assessment VL - 93 ID - 3319 ER - TY - JOUR AB - Background. The use of the emergency departments as a regular source of sick care has been increasing, despite the fact that it is costly and is often an inappropriate source of care. This study examines factors associated with routine use of emergency departments by using a national sample of US children. Methods. Data from the 1988 National Health Interview Survey on Child Health, a nationally representative sample of 17 710 children younger than 18 years, was linked to county-level health resource data from the Area Resource File. Bivariate and multivariate analyses were used to assess the association between children's use of emergency departments as their usual sources of sick care and predisposing need and enabling characteristics of the families, as well as availability of health resources in their communities. Results. In 1988 3.4% or approximately 2 million US children younger than 18 years were reported to use emergency departments as their usual sources of sick care. Significant demographic risk factors for reporting an emergency department as a usual source of sick care included black versus white race (odds ratio [OR], 2.08), single-parent versus two-parent families (OR, 1.53), mothers with less than a high school education versus those with high school or more (OR, 1.76), poor versus nonpoor families (OR, 1.76), and living in an urban versus suburban setting (OR, 1.38). Specific indicators of need, such as recurrent health conditions (asthma, tonsillitis, headaches, and febrile seizures), were not associated with routine use of emergency departments for sick care. Furthermore, health insurance status and specifically Medicaid coverage had no association with use of the emergency department as a usual source of sick care. Compared with children who receive well child care in private physicians' offices or health maintenance organizations, children whose sources of well child care were neighborhood health centers were more likely to report emergency departments for sick care (OR, 2.01). Children residing in counties where the supply of primary care physicians was in the top quintile had half the odds (OR, 0.50) of reporting emergency departments as usual sources of sick care. Conclusions. Reliance on hospital emergency departments for routine sick care is strongly associated with demographic and social characteristics of the child and family, the type and source of available well child care, and the supply of primary care physicians. Because health insurance status was not a significant predictor of use, public policies aimed at reducing the use of emergency departments by children will need to address other factors. These include the organizational characteristics and responsiveness of the health care system and the motivation of families for routine use of hospital emergency departments. AN - WOS:A1996UU13700005 AU - Halfon, N. AU - Newacheck, P. W. AU - Wood, D. L. AU - StPeter, R. F. DA - Jul IS - 1 N1 - Halfon, N Newacheck, PW Wood, DL StPeter, RF PY - 1996 SN - 0031-4005 SP - 28-34 ST - Routine emergency department use for sick care by children in the United States T2 - Pediatrics TI - Routine emergency department use for sick care by children in the United States UR - ://WOS:A1996UU13700005 VL - 98 ID - 2926 ER - TY - JOUR AB - An interdisciplinary program with the goal of teaching self-regulation and minimizing excessive narcotic use in the management of vaso-occlusive pain (V-O) in pediatric sickle cell anemia patients is described. A small group of patients do not respond well to any of our outpatients or inpatients medical regimens, leading us to suspect that psychological factors are influencing pain reports. We outline our multi-faceted assessment approach to evaluating such psychological factors, which includes a pain flow sheet, symptom check list, and a psychophysiologic profile. Published reports of self-regulation training including biofeedback, relaxation/imagery, and hypnosis have been associated with decreased pain symptoms, reduced number of emergency room and hospital visits for pain, decreased narcotic use, and increased school attendance. A case study of a nine-year-old patient with sickle cell disease is described before and after self-regulation training. Finally, other alternative approaches that avoid excessive narcotic use are discussed with some case reports. AD - Rainbow Sickle Cell Anemia Center, Rainbow Babies & Childrens Hospital, Cleveland, Ohio. AN - 1428615 AU - Hall, H. AU - Chiarucci, K. AU - Berman, B. DP - NLM ET - 1992/01/01 IS - 1-4 KW - *Adaptation, Psychological Anemia, Sickle Cell/physiopathology/*psychology Arousal/physiology *Biofeedback, Psychology/physiology Child Female Humans *Hypnosis Imagination *Pain Measurement Psychophysiology Relaxation Therapy *Sick Role LA - eng N1 - Hall, H Chiarucci, K Berman, B Case Reports Journal Article United States Int J Psychosom. 1992;39(1-4):28-33. PY - 1992 SN - 0884-8297 (Print) 0884-8297 SP - 28-33 ST - Self-regulation and assessment approaches for vaso-occlusive pain management for pediatric sickle cell anemia patients T2 - Int J Psychosom TI - Self-regulation and assessment approaches for vaso-occlusive pain management for pediatric sickle cell anemia patients VL - 39 ID - 3898 ER - TY - JOUR AB - The Canadian Back Education Units (CBEU) in a review of 6418 participants found a significant subjective improvement in 69% of the participants. This figure improved to 80% when only patients who experienced back pain for six months or less were considered. Ninety-seven percent of the participants considered the back education program helpful. Patients who had completed their high school education, who believed that they understood the mechanism of the pain, and who recognized an emotional component to the problem had the best results. Functional improvement was most pronounced in the activities most often performed. Patients with pain persistently radiating below the knee and patients receiving workmen's compensation did not fare as well. Using a computer analysis of the variation in test scores from pretest to the review class, a statistically valid positive correlation was established between the patient's subjective improvement and the amount of information retained. The CBEU are an efficient, effective, well received, and cost-effective therapeutic modality in the conservative treatment of chronic low back pain. AN - 6225591 AU - Hall, H. AU - Iceton, J. A. DA - Oct DP - NLM ET - 1983/10/01 IS - 179 KW - Adult Back Pain/diagnosis/psychology/*therapy Female Humans Male Middle Aged *Patient Education as Topic LA - eng N1 - Hall, H Iceton, J A Journal Article Research Support, Non-U.S. Gov't United States Clin Orthop Relat Res. 1983 Oct;(179):10-7. PY - 1983 SN - 0009-921X (Print) 0009-921x SP - 10-7 ST - Back school. An overview with specific reference to the Canadian Back Education Units T2 - Clin Orthop Relat Res TI - Back school. An overview with specific reference to the Canadian Back Education Units ID - 4139 ER - TY - JOUR AB - A 6-year-old female presented with chronic intermittent abdominal pain for 1 year. She underwent extensive investigation, imaging and invasive procedures with multiple emergency room visits. It caused a significant distress to the patient and the family with multiple missing days at school in addition to financial burden and emotional stress the child endured. When clinical picture was combined with laboratory finding of macrocytic anemia, a diagnosis of hypothyroidism was made. Although chronic abdominal pain in pediatric population is usually due to functional causes such as irritable bowel syndrome, abdominal migraine and functional abdominal pain. Hypothyroidism can have unusual presentation including abdominal pain. The literature on abdominal pain as the main presentation of thyroid disorder is limited. Pediatricians should exclude hypothyroidism in a patient who presents with chronic abdominal pain. Contrast to its treatment, clinical presentation of hypothyroidism can be diverse and challenging, leading to a delay in diagnosis and causing significant morbidity. AN - WOS:000443262500001 AU - Hamid, K. AU - Dayalani, N. AU - Jabbar, M. AU - Saah, E. C7 - 180076 DA - Aug DO - 10.1530/edm-18-0076 N1 - Hamid, Kewan Dayalani, Neha Jabbar, Muhammad Saah, Elna 2052-0573 PY - 2018 ST - My tummy hurts - a case report of abdominal pain and macrocytic anemia caused by hypothyroidism T2 - Endocrinology Diabetes and Metabolism Case Reports TI - My tummy hurts - a case report of abdominal pain and macrocytic anemia caused by hypothyroidism UR - ://WOS:000443262500001 ID - 1998 ER - TY - JOUR AB - Background: Low back pain is a significant problem not only for the adult, but also during youth. However, the relationship between low back pain during youth and the duration or types of competitive sports has not been clarified. Hypothesis: Low back pain during youth is associated with the duration and types of competitive sports. Study Design: Cross-sectional study; Level of evidence, 4. Methods: Study participants were 4667 new university students who, from 2004 to 2006, answered a questionnaire concerning low back pain and their participation in competitive sports. The participants were divided into a "no'' group (NO), a middle group (MID), and a high group (HI) based on the duration of participation in competitive sports. The answers to the questionnaire were analyzed using the Cochran-Mantel-Haenszel test. Furthermore, we selected students who had participated in the same sport for 5 or more years and categorized the students according to the type of sport. Differences in low back pain among the groups were analyzed using logistic regression with the NO group as the reference group. Results: There were statistically significant linear associations in the NO, MID, and HI groups, with 50.0%, 61.8%, and 71.7%, respectively, of the students experiencing low back pain. Among the NO, MID, and HI groups, 4.4%, 5.7%, 9.6%, respectively, had experienced school absence due to low back pain; and 4.0%, 8.5%, and 14.6%, respectively had low back pain with associated lower extremity pain and numbness. All 8 sports groups that were analyzed had experienced low back pain significantly higher than the NO group, and the odds ratios differed by sport with the highest (3.8) for the volleyball group. Conclusion: Excessive exposure to competitive sports activities during youth was associated with low back pain and symptoms in the lower extremities, with the severity varying with the sport. To reduce low back pain in youth, factors that may be causing low back pain, such as sport-specific postures and motions, need to be investigated. AN - WOS:000276167200018 AU - Hangai, M. AU - Kaneoka, K. AU - Okubo, Y. AU - Miyakawa, S. AU - Hinotsu, S. AU - Mukai, N. AU - Sakane, M. AU - Ochiai, N. DA - Apr DO - 10.1177/0363546509350297 IS - 4 N1 - Hangai, Mika Kaneoka, Koji Okubo, Yu Miyakawa, Shumpei Hinotsu, Shiro Mukai, Naoki Sakane, Masataka Ochiai, Naoyuki PY - 2010 SN - 0363-5465 SP - 791-796 ST - Relationship Between Low Back Pain and Competitive Sports Activities During Youth T2 - American Journal of Sports Medicine TI - Relationship Between Low Back Pain and Competitive Sports Activities During Youth UR - ://WOS:000276167200018 VL - 38 ID - 2556 ER - TY - JOUR AB - BACKGROUND: Low back pain is prevalent and is a frequent cause of disability and sick leave among working adults. Individuals with low back pain often consult general practice or other health care providers which often results in a unilateral intervention focussed on their symptoms. Employment is associated with physical and mental well-being, so, patients may benefit from an early additional occupational medicine intervention. For individuals with physically demanding jobs it can be especially challenging to retain their jobs. The aim of the 'GoBack trial' is to develop and evaluate the efficacy and feasibility of an occupational medicine intervention for individuals with low back pain in physically demanding jobs. METHODS/DESIGN: We will conduct a randomised controlled trial enrolling 300 participants with difficulty in maintaining physically demanding jobs due to low back pain for a current period of 2 to 4 weeks. Participants will be randomised and stratified according to their age and gender before being allocated in a 1:1 ratio to either control or additional occupational medicine intervention. Both groups will receive conventional treatment for their low back pain during the study. All participants will be thoroughly assessed for causes of low back pain and potential prognostic factors by questionnaires, clinical specialist assessments and magnetic resonance imaging (MRI) scans of the lumbar spine. Primary outcome is the accumulated duration of self-assessed sick leave (in days) due to low back pain during 6 months from baseline. Secondary outcomes include general self-rated back pain, disability and screening for potential prognostic factors: fear avoidance behaviour, disability, health status and degenerative MRI findings. For tertiary purposes selected outcomes will also be assessed after 1 and 2 years from baseline. DISCUSSION: Many guidelines exist for the management of low back pain, but they provide limited guidance on occupational aspects. The findings from this randomised trial will provide high-quality evidence for the efficacy and feasibility of an occupational medicine intervention model for individuals with low back pain in physically demanding jobs. TRIAL REGISTRATION: This trial was registered with ClinicalTrials.gov (identifier: NCT02015572 ) on 29 November 2013. AD - Department of Rheumatology, The Parker Institute, Copenhagen University Hospital, Bispebjerg and Frederiksberg Hospital, Nordre Fasanvej 57, 2000, Frederiksberg, Copenhagen, Denmark. bjarke.hansen.01@regionh.dk. Department of Occupational and Environmental Medicine, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Bispebjerg Bakke 23, DK-2400, Copenhagen, NV, Denmark. Lilli.Kirkeskov@regionh.dk. Department of Rheumatology, The Parker Institute, Copenhagen University Hospital, Bispebjerg and Frederiksberg Hospital, Nordre Fasanvej 57, 2000, Frederiksberg, Copenhagen, Denmark. robin.christensen@frh.regionh.dk. Department of Occupational and Environmental Medicine, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Bispebjerg Bakke 23, DK-2400, Copenhagen, NV, Denmark. Luise.Moelenberg.Bergtrup@regionh.dk. Department of Occupational and Environmental Medicine, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Bispebjerg Bakke 23, DK-2400, Copenhagen, NV, Denmark. Ellen.Boetker.Pedersen@regionh.dk. Department of Occupational and Environmental Medicine, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Bispebjerg Bakke 23, DK-2400, Copenhagen, NV, Denmark. Jakob.falk.teilya@regionh.dk. Department of Radiology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Nordre Fasanvej 57, 2000, Frederiksberg, Copenhagen, Denmark. mikael.boesen@gmail.com. Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Nordre Fasanvej 57, 2000, Frederiksberg, Copenhagen, Denmark. gilles.ludger.fournier@regionh.dk. Department of Rheumatology, The Parker Institute, Copenhagen University Hospital, Bispebjerg and Frederiksberg Hospital, Nordre Fasanvej 57, 2000, Frederiksberg, Copenhagen, Denmark. Henning.Bliddal@regionh.dk. Department of Occupational and Environmental Medicine, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Bispebjerg Bakke 23, DK-2400, Copenhagen, NV, Denmark. ann.isabel.kryger@regionh.dk. AN - 25887302 AU - Hansen, B. B. AU - Kirkeskov, L. AU - Christensen, R. AU - Begtrup, L. M. AU - Pedersen, E. B. AU - Teilya, J. F. AU - Boesen, M. AU - Fournier, G. L. AU - Bliddal, H. AU - Kryger, A. I. C2 - PMC4423126 DA - Apr 16 DO - 10.1186/s13063-015-0684-3 DP - NLM ET - 2015/04/19 KW - Absenteeism Adolescent Adult Aged Clinical Protocols Denmark Feasibility Studies Female Humans *Job Description Low Back Pain/diagnosis/physiopathology/psychology/*therapy Magnetic Resonance Imaging Male Middle Aged *Occupational Health Pain Management/*methods Pain Measurement Patient Care Team *Personnel Turnover Research Design *Return to Work Sick Leave Surveys and Questionnaires Time Factors Treatment Outcome Work Capacity Evaluation *Workload Young Adult LA - eng N1 - 1745-6215 Hansen, Bjarke Brandt Kirkeskov, Lilli Christensen, Robin Begtrup, Luise Mølenberg Pedersen, Ellen Bøtker Teilya, Jakob Falk Boesen, Mikael Fournier, Gilles Ludger Bliddal, Henning Kryger, Ann Isabel Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't Trials. 2015 Apr 16;16:166. doi: 10.1186/s13063-015-0684-3. PY - 2015 SN - 1745-6215 SP - 166 ST - Retention in physically demanding jobs of individuals with low back pain: study protocol for a randomised controlled trial T2 - Trials TI - Retention in physically demanding jobs of individuals with low back pain: study protocol for a randomised controlled trial VL - 16 ID - 3492 ER - TY - JOUR AB - BACKGROUND: Pain problems are common in children and adolescents. Measures of health-related quality of life (HRQoL) can be used to assess children's subjective perspectives of pain experience and its impact on their life. The aims of the study were to describe HRQoL and the prevalence of pain in a nonclinical population of children and adolescents, and to analyze the relationships between HRQoL, pain, sex, and age in a sample of children and adolescents aged 8-18 years. METHODS: This cross-sectional study involved a cluster sample of 20 randomly selected schools drawn within a region of Norway. The final study sample included 1099 children and adolescents. We measured HRQoL using the generic questionnaire KIDSCREEN-52 and pain using questions from the Lübeck Pain-Screening Questionnaire. Multiple regression was used to analyze relationships between HRQoL and sex, age, and pain. RESULTS: The response rate was 74%. A large percentage of the sample, 60%, reported pain, and girls reported significantly more pain than boys, 76% of the girls in the age group 16-18 years reported pain. The KIDSCREEN-52 scores differed between girls and boys, and on average, girls reported a significantly lower HRQoL than boys on most dimensions. Pain problems were associated with lower HRQoL, and older girls were most impaired by pain. CONCLUSIONS: The findings from this study indicate that pain problems are highly prevalent in children, and more prevalent in girls than in boys. HRQoL was impaired for all 10 dimensions of the KIDSCREEN-52 in children with pain. The subscales self-perception, psychological well-being, mood, relationship with parents, and school environment were most affected. AU - Haraldstad, Kristin AU - Christophersen, Knut-Andreas AU - Helseth, Sølvi DA - 2017/07/24/ DO - 10.1186/s12887-017-0927-4 DP - PubMed IS - 1 J2 - BMC Pediatr KW - Adolescent Adolescents Age Distribution Child Children Cross-Sectional Studies Female Health Status Indicators Health Surveys HRQoL Humans Linear Models Male Norway Pain Pain Measurement Prevalence Public health Quality of Life School survey Sex Distribution LA - eng PY - 2017 SN - 1471-2431 SP - 174 ST - Health-related quality of life and pain in children and adolescents T2 - BMC pediatrics TI - Health-related quality of life and pain in children and adolescents: a school survey UR - http://www.ncbi.nlm.nih.gov/pubmed/28738818 VL - 17 ID - 69 ER - TY - JOUR AB - OBJECTIVE: To examine whether a service guideline reducing postoperative opioid prescription quantities and caregiver-reported education to use nonopioid analgesics first are associated with caregiver-reported pain control after pediatric tonsillectomy. STUDY DESIGN: Prospective cohort study (July 2018-April 2019). SETTING: Pediatric otolaryngology service at a tertiary academic children's hospital. SUBJECTS AND METHODS: Caregivers of patients aged 1 to 11 years undergoing tonsillectomy (N = 764) were surveyed 7 to 21 days after surgery regarding pain control, education to use nonopioid analgesics first, and opioid use. Respondents who were not prescribed opioids or had missing data were excluded. Logistic regression modeled caregiver-reported pain control as a function of service guideline implementation (December 2018) recommending 20 rather than 30 doses for postoperative opioid prescriptions and caregiver-reported analgesic education, adjusting for patient demographics. RESULTS: Among 430 respondents (56% response), 387 patients were included. The sample was 43% female with a mean age of 5.0 years (SD, 2.5). Pain control was reported as good (226 respondents, 58%) or adequate/poor (161 respondents, 42%). Mean opioid prescription quantity was 27 doses (SD, 7.9) before and 21 doses (SD, 6.1) after guideline implementation (P < .001). Education to use nonopioids first was reported by 308 respondents (80%). In regression, prescribing guideline implementation was not associated with pain control (adjusted odds ratio, 1.3; 95% CI, 0.9-2.0; P = .22), but caregiver-reported education to use nonopioids first was associated with a higher odds of good pain control (adjusted odds ratio, 1.9; 95% CI, 1.1-3.2; P = .02). CONCLUSION: Caregiver education to use nonopioid analgesics first may be a modifiable health care practice to improve pain control as postoperative opioid prescription quantities are reduced. AD - Department of Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA. Michigan Opioid Prescribing Engagement Network, University of Michigan, Ann Arbor, Michigan, USA. Division of Pediatric Otolaryngology, Department of Otolaryngology-Head and Neck Surgery, Michigan Medicine, Ann Arbor, Michigan, USA. Department of Pediatrics, Susan B. Meister Child Health Evaluation and Research Center, University of Michigan Medical School, Ann Arbor, Michigan, USA. Section of Plastic Surgery, Department of Surgery, Michigan Medicine, Ann Arbor, Michigan, USA. Section of Pediatric Surgery, Department of Surgery, Michigan Medicine, Ann Arbor, Michigan, USA. AN - 32204656 AU - Harbaugh, C. M. AU - Vargas, G. AU - Sloss, K. R. AU - Bohm, L. A. AU - Cooper, K. A. AU - Thatcher, A. L. AU - Zopf, D. A. AU - Chua, K. P. AU - Waljee, J. F. AU - Gadepalli, S. K. DA - May DO - 10.1177/0194599820912033 DP - NLM ET - 2020/03/25 IS - 5 KW - Analgesics, Opioid/*administration & dosage Caregivers/*education Child Child, Preschool Female Humans Infant Male Pain Management/*methods Pain, Postoperative/*drug therapy Practice Patterns, Physicians'/*statistics & numerical data Prospective Studies *Tonsillectomy *opioid *pain management *patient education *pediatric LA - eng N1 - 1097-6817 Harbaugh, Calista M Vargas, Gracia Sloss, Kenneth R Bohm, Lauren A Cooper, Karen A Thatcher, Aaron L Zopf, David A Chua, Kao-Ping Waljee, Jennifer F Gadepalli, Samir K K08 DA048110/DA/NIDA NIH HHS/United States Journal Article Research Support, Non-U.S. Gov't England Otolaryngol Head Neck Surg. 2020 May;162(5):746-753. doi: 10.1177/0194599820912033. Epub 2020 Mar 24. PY - 2020 SN - 0194-5998 SP - 746-753 ST - Association of Opioid Quantity and Caregiver Education with Pain Control after Pediatric Tonsillectomy T2 - Otolaryngol Head Neck Surg TI - Association of Opioid Quantity and Caregiver Education with Pain Control after Pediatric Tonsillectomy VL - 162 ID - 3570 ER - TY - JOUR AB - Objective The study objective was to identify the perceptions of children with sickle cell disease (SCD) in the school environment. Methods Semistructured interviews (N = 14) were conducted with pediatric patients ages 6 to 10 who attended Metro Nashville Public Schools. These participants were recruited through the Vanderbilt Sickle Cell Disease Clinic. Participants were asked about the perceived efficacy of their teachers to (1) understand SCD; (2) communicate with students regarding SCD; (3) handle an SCD-related pain episode in school; and (4) identify methods to compensate for school absenteeism associated with an SCD diagnosis. Content analysis identified underlying themes. Results Five themes emerged that highlighted the perceptions and recommendations of children with SCD in the school environment: (1) perceptions that allow students to prevent SCD from limiting their school experience; (2) administrator actions to alleviate challenges associated with SCD; (3) communication about SCD; (4) how SCD interferes with school activities; and (5) ways students advocate for themselves. Students also provided four areas of recommendations for school personnel: (1) ways teachers can help with school activities; (2) make-up work for school absences; (3) empowering students with SCD; and (4) helping with SCD episodes at school. Conclusions Students with SCD advocated strongly for their needs at school to attain their education. However, they perceived school personnel to lack knowledge about SCD management. This could be overcome with a handbook specific for teachers of students with SCD that could address each of the five themes. AN - WOS:000453911400014 AU - Haridasa, N. AU - DeBaun, M. R. AU - Sanger, M. AU - Mayo-Gamble, T. L. C7 - e27507 DA - Feb DO - 10.1002/pbc.27507 IS - 2 N1 - Haridasa, Naeha DeBaun, Michael R. Sanger, Maureen Mayo-Gamble, Tilicia L. Mayo-Gamble, Tilicia/0000-0002-9303-5266; DeBaun, Michael/0000-0002-0574-1604 1545-5017 PY - 2019 SN - 1545-5009 ST - Student perspectives on managing sickle cell disease at school T2 - Pediatric Blood & Cancer TI - Student perspectives on managing sickle cell disease at school UR - ://WOS:000453911400014 VL - 66 ID - 1956 ER - TY - JOUR AB - A cohort of 38-year-old men and women were studied for leisure time physical exercise in relation to low back pain (LBP), education, work, social class and smoking by a self-administered questionnaire. At the age of 14 years, the subjects had been interviewed by their school doctor regarding history of LBP and radiographs of the thoracic and lumbar spine were taken. The results show no positive correlation between radiographic changes and LBP in the adolescent period and decreased physical activity in adulthood. Physical activity for at least 3 h/week reduces the risk of LBP measured as lifetime, 1-year and point prevalence. Eighty-five percent of the subjects who reported taking physical exercise for at least 3 h/week had participated in sports activity almost constantly since their school days and these reported being in better condition than the rest of the cohort. Otherwise they did not have a healthier mode of life. No physical exercise during leisure time was associated with a short school education, unskilled work, unemployment and sickness, low social class, divorce, living in an apartment and smoking. Sixty percent had never or not for many years been interested in participating in sports. Badminton and tennis were the most common sports practised (36%), followed by gymnastics (32%), ball games-soccer and team handball-(25%), running (20%) and swimming (18%). Gymnastics and swimming seem to reduce LBP significantly. Our results show a falling interest in participating in sports activities over time, with 68% of the subjects being members of an athletic association previously, but only 29% currently. Women were more physically inactive during leisure time, probably because of their dual role. Logistic regression analysis indicates that physical activity is related to a long school education, high social class and regular sports activity over time. AU - Harreby, M. AU - Hesselsøe, G. AU - Kjer, J. AU - Neergaard, K. DA - 1997 DO - 10.1007/BF01301433 DP - PubMed IS - 3 J2 - Eur Spine J KW - Adolescent Adult Cohort Studies Educational Status Exercise Female Follow-Up Studies Humans Leisure Activities Low Back Pain Male Prevalence Prospective Studies Risk Factors Smoking Sports Surveys and Questionnaires Time Factors Work LA - eng PY - 1997 SN - 0940-6719 SP - 181-186 ST - Low back pain and physical exercise in leisure time in 38-year-old men and women T2 - European Spine Journal: Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society TI - Low back pain and physical exercise in leisure time in 38-year-old men and women: a 25-year prospective cohort study of 640 school children UR - http://www.ncbi.nlm.nih.gov/pubmed/9258636 VL - 6 ID - 119 ER - TY - JOUR AB - This study was designed as a cross-sectional questionnaire-based survey of low back pain (LBP) in 13- to 16-year-old Danish school children. The cohort consisted of 671 boys and 718 girls in eighth and ninth grade in 46 municipal schools in three counties of Sealand. All the pupils filled in a questionnaire with LBP as the main topic and were at the same time examined by the school doctors. The first part of the questionnaire contained questions about leisure time sports activity, TV watching, PC use, job in leisure time and smoking. The second part dealt with LBP in relation to frequency and severity, influence on daily living and use of the health system. The school doctor measured body height and weight, (BMI), degree of hypermobility and the tightness of the hamstring muscles. The results showed a cumulative life-time prevalence of LBP of 58.9%, a 1-year prevalence of 50.8% and an increase in LBP prevalence of 6.4% from 14 to 15 years of age, independent of gender. Fourteen percent (141 F, 54 M) fulfilled the criteria for general hypermobility and 12.2% (45 F, 124 M) had tightness of hamstring muscles of more than 40 degrees. Recurrent/continuous LBP in a moderate to severe degree was recorded in 19.4% of children (182 F, 88 M). This was positively correlated to female gender, BMI more than 25 kg/m(2), competitive sport for boys, poor physical fitness, daily smoking, heavy jobs in leisure time, increased use of the health system and reduced life quality. Stepwise logistic regression analysis indicates that female gender, daily smoking and heavy jobs are important associated factors for severe LBP in adolescents, with an observed probability of 46% if all factors are present. We don't know yet whether these factors are of any causal importance in the development of severe LBP. AU - Harreby, M. AU - Nygaard, B. AU - Jessen, T. AU - Larsen, E. AU - Storr-Paulsen, A. AU - Lindahl, A. AU - Fisker, I. AU - Laegaard, E. DA - 1999 DO - 10.1007/s005860050203 DP - PubMed IS - 6 J2 - Eur Spine J KW - Adolescent Cohort Studies Cross-Sectional Studies Denmark Female Humans Low Back Pain Male Prevalence Risk Factors Sex Factors Smoking LA - eng PY - 1999 SN - 0940-6719 SP - 444-450 ST - Risk factors for low back pain in a cohort of 1389 Danish school children T2 - European Spine Journal: Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society TI - Risk factors for low back pain in a cohort of 1389 Danish school children: an epidemiologic study UR - http://www.ncbi.nlm.nih.gov/pubmed/10664301 VL - 8 ID - 122 ER - TY - JOUR AB - Many behaviors, such as physical inactivity or a poor diet, that put adults at risk for chronic diseases are established in childhood. This manuscript describes the outcomes of a comprehensive school health project, the Kansas LEAN School Intervention Project. The Kansas LEAN School Intervention Project in Salina and Dighton had four components, three of which were school based: (a) modified school lunches, (b) enhanced nutrition education, and (c) increased opportunities for physical activity. The fourth component, actions taken by a community partnership, is described elsewhere. Data from two case studies were used to address three primary evaluation questions: (a) did changes in the school lunch menu reduce the fat content yet maintain calories in meals served? ( b) did nutrition knowledge, skills, and attitudes of students improve? and (c) did students' physical fitness improve? The findings suggest that the project was successful in reducing the fat content in school lunches in both communities from baseline levels of approximately 38% calories from fat to the target goal of 30% calories from fat during the 1993-94 school year.The schools also maintained adequate calories for students in this age group. Students' knowledge, skills, and behaviors related to nutrition as well as their physical fitness improved in both Kansas communities. The strengths and limitations of this strategy of making healthy choices easy choices through school-based intervention are discussed. (PsycINFO Database Record (c) 2016 APA, all rights reserved) AU - Harris, Kari Jo AU - Paine-Andrews, Adrienne AU - Richter, Kimber P. AU - Lewis, Rhonda K. AU - Johnston, Judy A. AU - James, Vickie AU - Henke, Lori AU - Fawcett, Stephen B. DA - 1997 DO - 10.1016/S0022-3182(97)70198-5 DP - APA PsycNET IS - 4 KW - Chronic Illness Elementary School Students Food Intake Health Education Nutrition Physical Activity Physical Education Risk Factors School Based Intervention PY - 1997 SN - 0022-3182(Print) SP - 196-202 ST - Reducing elementary school children's risks for chronic diseases through school lunch modifications, nutrition education, and physical activity interventions T2 - Journal of Nutrition Education TI - Reducing elementary school children's risks for chronic diseases through school lunch modifications, nutrition education, and physical activity interventions UR - https://psycnet.apa.org/record/2008-09772-003 VL - 29 ID - 3 ER - TY - JOUR AB - AGRICULTURAL SCIENCE AND TECHNOLOGY INFORMATION AU - Harris, K. J. AU - Richter, K. P. AU - Paine-Andrews, A. AU - Lewis, R. K. AU - Johnston, J. A. AU - James, V. AU - Henke, L. AU - Fawcett, S. B. DA - 1997 DP - agris.fao.org LA - English PY - 1997 SN - 0022-3182 ST - Community partnerships T2 - Journal of nutrition education TI - Community partnerships: review of selected models and evaluation of two case studies UR - https://agris.fao.org/agris-search/search.do?recordID=US201302874005 Y2 - 2021/06/09/18:31:15 ID - 4 ER - TY - JOUR AB - Chronic pain is prevalent in children and can limit their ability to attend school, socialize with peers, and participate in physical activity. This article describes the advantages of using a multidisciplinary approach to evaluating and treating children with chronic pain and discusses medications and techniques for managing pain and restoring functionality. AD - Department of Anesthesiology, Mayo Clinic, USA. AN - 21485928 AU - Harrison, T. DA - Mar DP - NLM ET - 2011/04/14 IS - 3 KW - Adrenal Cortex Hormones/administration & dosage Analgesics/administration & dosage/adverse effects Child Chronic Disease Combined Modality Therapy *Cooperative Behavior Humans Hypnotics and Sedatives/administration & dosage/adverse effects *Interdisciplinary Communication Pain/*rehabilitation *Patient Care Team Relaxation Therapy LA - eng N1 - Harrison, Tracy Journal Article United States Minn Med. 2011 Mar;94(3):48-50. PY - 2011 SN - 0026-556X (Print) 0026-556x SP - 48-50 ST - Pediatric chronic pain: there is hope T2 - Minn Med TI - Pediatric chronic pain: there is hope VL - 94 ID - 3470 ER - TY - JOUR AB - The results of anti-inflammatory treatment for children and adolescents with rheumatic diseases have been particularly improved within the last 15 years. Still there are significant deficiencies in the treatment of functional impairments. Integration of sport activities has turned out to be a key factor when optimising the existing therapy. Therapy concepts with sport activities in patients with rheumatic diseases have to consider the current status of disease as well as the individual interests of the patients. During the active phases of disease movements should produce only low joint loads, while in inactive phases activities should have proportioned joint loads and in the restitution sport should be practiced with attentiveness. On the basis of results from 3D-gait analysis and physical fitness assessment of children with juvenile idiopathic arthritis a PMW ("preventive mobility workout") (as a practice routine) has been developed at the "Deutsches Zentrum fur Kinder-und Jugendrheumatologie". This programme aims to support the rehabilitation and secondariy aims towards prevention within inactive phases of the disease. The various exercises contribute to improve the mobility, muscle strength, stability and the balance of the patients. The training lasts approximately 10 min and should be performed daily. The inclusion in school sport is desirable and should be decided depending upon disease activity. AN - WOS:000305753500002 AU - Hartmann, M. AU - Kreuzpointner, F. AU - Schrodl, S. AU - Spamer, M. AU - Georgi, M. AU - Haas, J. P. DA - Jun DO - 10.1055/s-0032-1311573 IS - 3 N1 - Hartmann, M. Kreuzpointner, F. Schroedl, S. Spamer, M. Georgi, M. Haas, J-P 1438-9940 PY - 2012 SN - 0341-051X SP - 154-160 ST - The Role of Sport in Rheumatic Diseases in Childhood and Adolescence T2 - Aktuelle Rheumatologie TI - The Role of Sport in Rheumatic Diseases in Childhood and Adolescence UR - ://WOS:000305753500002 VL - 37 ID - 2429 ER - TY - JOUR AB - BackgroundTaking part in physical education is an important element of social participation for children with chronic diseases. Nevertheless, children suffering from rheumatism mostly receive recommendations to stop sport activities either completely or partially, without underlying scientific guidelines.ObjectiveThe aim was the development of an IT-tool based on scientific data in order to create individualized recommendations for sport activities plus verification of its practical feasibility.Material and methodsAn interdisciplinary group of experts developed and approved aprototype of the rheumatism and sports compass (Rheuma und Sport Kompass, RSK) based on the literature and own experience. They considered individual health factors and biomechanics of sports functions. The prototype was tested, revised and reconsidered in an interim evaluation. The resulting RSKv1 was evaluated in aclinical observation phase with 61patients. The results were subsequently incorporated into the final version of RSK during an interdisciplinary decision-making process. This was verified in afeasibility study with afollow-up survey of rheumatic patients with aRSK partial participation certification for physical education including: clinical assessment during 8lessons of physical education and after 8lessons of physical education. Teachers rated the RSK online after 8lessons. The evaluation was descriptive and differences in mean values were tested.Results and discussionIn this study 50 patients and 31teachers were evaluated. The affliction of pain decreased in terms of frequency, amount and duration after physical education with RSK. No worsening in health was reported after participation in sports. The teachers rated the RSK as understandable, practicable and they felt confident to allow the patients to participate in classes. The RSK was rated significantly better than astandard certification text. With the RSK, patients can be advised to safely take part in physical education. AN - WOS:000445958100003 AU - Hartmann, M. AU - Merker, J. AU - Schrodl, S. AU - Konig, M. AU - Georgi, M. AU - Hinze, C. AU - Schwirtz, A. AU - Haas, J. P. DA - Oct DO - 10.1007/s00393-018-0518-2 IS - 8 N1 - Hartmann, M. Merker, J. Schroedl, S. Koenig, M. Georgi, M. Hinze, C. Schwirtz, A. Haas, J. -P. Hinze, Claas/0000-0001-9247-4729 1435-1250 PY - 2018 SN - 0340-1855 SP - 651-666 ST - Back to school physical education despite rheumatism. Development and testing of a sport scientificbased physical education certification T2 - Zeitschrift Fur Rheumatologie TI - Back to school physical education despite rheumatism. Development and testing of a sport scientificbased physical education certification UR - ://WOS:000445958100003 VL - 77 ID - 1990 ER - TY - JOUR AB - PURPOSE: To assess the prevalence of depressive symptoms and examine the contribution of demographics, disease severity, and health care use variables to depressive symptoms in sickle cell patients who had been in stable health for at least one month. PATIENTS AND METHODS: Subjects were a convenience sample of 27 men and 23 women selected during a routine visit to the sickle cell clinic at Howard University Hospital. Depression was assessed using a cut-off score from the Beck Depression Inventory (BDI) and related to a variety of health outcomes. RESULTS: The results of the analyses indicate that 44% (n=22) of the sample scored within the mild to severe (>20) range of depression on the BDI. Depressed sickle cell patients were more frequently treated in emergency rooms and more likely to be hospitalized with vaso-occlusive crises. Patients more likely to be depressed were: those with low family income (<$10,000); less than high school education; female; those who had multiple blood transfusions; poor pain control; inadequate social support; hydroxyurea use; and had histories of frequent vaso-occlusive crises. CONCLUSION: The prevalence of depressive symptoms in sickle cell patients is high compared to the general African American population. Our findings confirmed previous studies examining the occurrence of depression in adults with sickle cell disease. Treatment of depression should be strongly considered to improve the quality of life and probably disease course in sickle cell patients. AD - Center for Sickle Cell Disease, Howard University Hospital, Washington, DC 20059, USA. phasan@hotmail.com AN - 12911250 AU - Hasan, S. P. AU - Hashmi, S. AU - Alhassen, M. AU - Lawson, W. AU - Castro, O. C2 - PMC2594635 DA - Jul DP - NLM ET - 2003/08/13 IS - 7 KW - African Americans Anemia, Sickle Cell/*epidemiology/psychology Comorbidity Depression/*epidemiology Female Humans Male Prevalence Social Support LA - eng N1 - Hasan, Syed Parwez Hashmi, Shahzad Alhassen, Mohammed Lawson, William Castro, Oswaldo Journal Article J Natl Med Assoc. 2003 Jul;95(7):533-7. PY - 2003 SN - 0027-9684 (Print) 0027-9684 SP - 533-7 ST - Depression in sickle cell disease T2 - J Natl Med Assoc TI - Depression in sickle cell disease VL - 95 ID - 4144 ER - TY - JOUR AB - It is wrong to believe that back pain only burdens adults: the yearly incidence during growth ranges from 10-20%, continuously increasing from childhood to adolescence. Rapid growth-related muscular dysbalance and insufficiency, poor physical condition in an increasingly sedentary adolescent community or - vice versa - high level sports activities, account for the most prevalent functional pain syndromes. In contrast to adults the correlation of radiographic findings with pain is high: the younger the patient, the higher the probability to establish a rare morphologic cause such as benign or malignant tumours, congenital malformations and infections. In children younger than 5 years old, the likelihood is more than 50%. The following red flags should lower the threshold for a quick in-depth analysis of the problem: Age of the patient <5 years, acute trauma, functional limitation for daily activities, irradiating pain, loss of weight, duration >4 weeks, history of tumour, exposition to tuberculosis, night pain and fever. High level sport equals a biomechanical field test which reveals the biologic individual response of the growing spine to the sports-related forces. Symptomatic or asymptomatic inhibitory or stimulatory growth disturbances like Scheuermann disease, scoliosis or fatigue fractures represent the most frequent pathomorphologies. They usually occur at the disk-growth plate compound: intraspongious disk herniation, diminuition of anterior growth with vertebral wedging and apophyseal ring fractures often occur when the biomechanical impacts exceed the mechanical resistance of the cartilaginous endplates. Spondylolysis is a benign condition which rarely becomes symptomatic and responds well to conservative measures. Associated slippage of L5 on S1 is frequent but rarely progresses. The pubertal spinal growth spurt is the main risk factor for further slippage, whereas sports activity - even at a high level - is not. Therefore, the athlete should only be precluded from training if pain persists or in case of high grade slips. Perturbance of the sagittal profile with increase of lumbar lordosis, flattening of the thoracic spine and retroflexion of the pelvis with hamstrings contractures are strong signs for a grade IV olisthesis or spondyloptosis with subsequent lumbosacral kyphosis. Idiopathic scoliosis is not related to pain unless it is a marked (thoraco-) lumbar curve or if there is an underlying spinal cord pathology. Chronic back pain is an under recognised entity characterised by its duration (>3 months or recurrence within 3 months) and its social impacts such as isolation and absence from school or work. It represents an independent disease, uncoupled from any initial trigger. Multimodal therapeutic strategies are more successful than isolated, somatising orthopaedic treatment. Primary and secondary preventive active measures for the physically passive adolescents, regular sports medical check-up's for the young high level athletes, the awareness for the rare but potentially disastrous pathologies and the recognition of chronic pain syndromes are the cornerstones for successful treatment of back pain during growth. AN - WOS:000321906600002 AU - Hasler, C. C. C7 - w13714 DA - Jan DO - 10.4414/smw.2013.13714 N1 - Hasler, Carol C. 1424-3997 PY - 2013 SN - 1424-7860 ST - Back pain during growth T2 - Swiss Medical Weekly TI - Back pain during growth UR - ://WOS:000321906600002 VL - 143 ID - 2388 ER - TY - JOUR AB - Background: Hip arthroscopy is a safe and effective mechanism for treating femoroacetabular impingement symptoms in high level athletes. Bilateral symptoms occur in a subset of this population. Purpose: To discuss outcomes of bilateral hip arthroscopy in high-level athletes and compare a standard staged timeline for bilateral hip arthroscopic surgery versus an accelerated timeline. Study Design: Cohort study; Level of evidence, 3. Methods: A retrospective review of all staged bilateral hip arthroscopies was performed on high-level athletes over a 3-year period. Patients were categorized into cohorts based upon when the second procedure was performed (4-6 weeks after the index procedure or >6 weeks after the index procedure). Exclusion criteria included any prior hip surgery, advanced arthritis, previous pelvic or femoral fracture, or inflammatory arthropathy. Demographics, radiographic measurements, operative reports of procedures performed, and patient-reported outcomes (Hip Outcome Score-Activities of Daily Living, Hip Outcome Score-Sport Specific Subscale, modified Harris Hip Score, return to sports, return to same level of play) were compared between groups at 6-month, 1-year, and 2-year intervals, with the Student t test used for continuous data and a chi-square test used for categorical data. Results: 50 patients were identified: 22 in the accelerated surgery (AS) group and 28 in the standard surgery (SS) group. Age and number of collegiate participants were greater in the AS group, whereas the number of high school participants and the time away from sports were higher in the SS group. Preoperative alpha angles were significantly larger among the AS group, but no differences were found in postoperative alpha angles, center edge angles, or Tonnis grades. No significant difference was seen in patient-reported outcomes between the 2 groups at 6-month, 1-year, and 2-year follow-up. Conclusion: Bilateral hip arthroscopy performed 4 to 6 weeks apart is a safe and effective treatment option for athletes with bilateral femoroacetabular impingement and labral tears; the procedures entail a high rate of return to sports, return to the same level of sports, and decreased time lost from sports. This information could be useful for an athlete deciding on whether to proceed with bilateral hip arthroscopy and deciding on the timing for the procedures. AN - WOS:000507733200001 AU - Hassebrock, J. D. AU - Chhabra, A. AU - Makovicka, J. L. AU - Economopoulos, K. J. C7 - 0363546519895259 DA - Mar DO - 10.1177/0363546519895259 IS - 3 N1 - Hassebrock, Jeffrey D. Chhabra, Anikar Makovicka, Justin L. Economopoulos, Kostas J. 1552-3365 PY - 2020 SN - 0363-5465 SP - 654-660 ST - Bilateral Hip Arthroscopy in High-Level Athletes: Results of a Shorter Interval Between Staged Bilateral Hip Arthroscopies T2 - American Journal of Sports Medicine TI - Bilateral Hip Arthroscopy in High-Level Athletes: Results of a Shorter Interval Between Staged Bilateral Hip Arthroscopies UR - ://WOS:000507733200001 VL - 48 ID - 1849 ER - TY - JOUR AB - Although chronic pain in childhood can last into adulthood, few studies have evaluated the characteristics of adults with chronic pain who report childhood chronic pain. Thus, 1,045 new patients (mean age, 49.5 ± 15.4) at an academic tertiary care pain clinic were prospectively evaluated using validated self-report questionnaires. Patients also responded to questions about childhood pain. We found that almost 17% (n = 176) of adult chronic pain patients reported a history of chronic pain in childhood or adolescence, with close to 80% indicating that the pain in childhood continues today. Adults reporting childhood chronic pain were predominantly female (68%), commonly reported widespread pain (85%), and had almost 3 times the odds of meeting survey criteria for fibromyalgia (odds ratio [OR] = 2.94, 95% confidence interval [CI] = 2.04-4.23) than those denying childhood chronic pain. Similarly, those with childhood pain had twice the odds of having biological relatives with chronic pain (OR = 2.03, 95% CI = 1.39-2.96) and almost 3 times the odds of having relatives with psychiatric illness (OR = 2.85, 95% CI = 1.97-4.11). Lastly, compared to patients who did not report childhood chronic pain, those who did were more likely to use neuropathic descriptors for their pain (OR = 1.82, 95% CI = 1.26-2.64), have slightly worse functional status (B = -2.12, t = -3.10, P = .002), and have increased anxiety (OR = 1.77, 95% CI = 1.24-2.52). PERSPECTIVE: Our study revealed that 1 in 6 adult pain patients reported pain that dated back to childhood or adolescence. In such patients, evidence suggested that their pain was more likely to be widespread, neuropathic in nature, and accompanied by psychological comorbidities and decreased functional status. AD - Department of Anesthesiology, University of Michigan, Ann Arbor, Michigan. Electronic address: afton@med.umich.edu. AN - 24021576 AU - Hassett, A. L. AU - Hilliard, P. E. AU - Goesling, J. AU - Clauw, D. J. AU - Harte, S. E. AU - Brummett, C. M. DA - Nov DO - 10.1016/j.jpain.2013.06.010 DP - NLM ET - 2013/09/12 IS - 11 KW - Adolescent Adult Aged Child Chronic Pain/*diagnosis/*psychology Female Fibromyalgia/*diagnosis/psychology Humans Male Middle Aged Self Report Sex Factors Surveys and Questionnaires Chronic pain anxiety depression fibromyalgia functional status pediatric pain LA - eng N1 - 1528-8447 Hassett, Afton L Hilliard, Paul E Goesling, Jenna Clauw, Daniel J Harte, Steven E Brummett, Chad M Journal Article Research Support, Non-U.S. Gov't United States J Pain. 2013 Nov;14(11):1390-7. doi: 10.1016/j.jpain.2013.06.010. Epub 2013 Sep 7. PY - 2013 SN - 1526-5900 SP - 1390-7 ST - Reports of chronic pain in childhood and adolescence among patients at a tertiary care pain clinic T2 - J Pain TI - Reports of chronic pain in childhood and adolescence among patients at a tertiary care pain clinic VL - 14 ID - 3236 ER - TY - JOUR AB - OBJECTIVE: To evaluate the prevalence and role of psychiatric comorbidity and other psychological factors in patients with chronic Lyme disease (CLD). METHODS: We assessed 159 patients drawn from a cohort of 240 patients evaluated at an academic Lyme disease referral center. Patients were screened for common axis I psychiatric disorders (e.g., depressive and anxiety disorders); structured clinical interviews confirmed diagnoses. Axis II personality disorders, functional status, and traits like negative and positive affect and pain catastrophizing were also evaluated. A physician blind to psychiatric assessment results performed a medical evaluation. Two groups of CLD patients (those with post-Lyme disease syndrome and those with medically unexplained symptoms attributed to Lyme disease but without Borrelia burgdorferi infection) were compared with 2 groups of patients without CLD (patients recovered from Lyme disease and those with an identifiable medical condition explaining symptoms attributed to Lyme disease). RESULTS: After adjusting for age and sex, axis I psychiatric disorders were more common in CLD patients than in comparison patients (P = 0.02, odds ratio 2.64, 95% confidence interval 1.30-5.35), but personality disorders were not. Patients with CLD had higher negative affect, lower positive affect, and a greater tendency to catastrophize pain (P < 0.001) than comparison patients. All psychological factors except personality disorders were related to level of functioning. A predictive model based on these psychological variables was confirmed. Fibromyalgia was diagnosed in 46.8% of CLD patients. CONCLUSION: Psychiatric comorbidity and other psychological factors distinguished CLD patients from other patients commonly seen in Lyme disease referral centers, and were related to poor functional outcomes. AD - University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, New Brunswick, NJ 08903-0019, USA. a.hassett@umdnj.edu AN - 19035409 AU - Hassett, A. L. AU - Radvanski, D. C. AU - Buyske, S. AU - Savage, S. V. AU - Gara, M. AU - Escobar, J. I. AU - Sigal, L. H. DA - Dec 15 DO - 10.1002/art.24314 DP - NLM ET - 2008/11/28 IS - 12 KW - Adolescent Adult Affect Aged Chronic Disease Female Fibromyalgia/complications Humans Lyme Disease/*complications/psychology Male Mental Disorders/*complications Middle Aged Personality Disorders/complications LA - eng N1 - Hassett, Afton L Radvanski, Diane C Buyske, Steven Savage, Shantal V Gara, Michael Escobar, Javier I Sigal, Leonard H 1-K08-MH65360-01/MH/NIMH NIH HHS/United States 1-P20-MH74634-03/MH/NIMH NIH HHS/United States Comparative Study Journal Article Research Support, N.I.H., Extramural United States Arthritis Rheum. 2008 Dec 15;59(12):1742-9. doi: 10.1002/art.24314. PY - 2008 SN - 0004-3591 (Print) 0004-3591 SP - 1742-9 ST - Role of psychiatric comorbidity in chronic Lyme disease T2 - Arthritis Rheum TI - Role of psychiatric comorbidity in chronic Lyme disease VL - 59 ID - 3494 ER - TY - JOUR AB - Objective. Children with juvenile idiopathic arthritis (JIA) experience functional impairment due to joint manifestations of the disease. The aim of our present study was to assess health-related quality of life (HRQOL) and its predictors in a group of children and adolescents with JIA. Methods. The study sample includes all JIA patients (ages 6-18 years) who consulted a pediatric rheumatologist in Amsterdam, The Netherlands, between February 2009 and March 2010. HRQOL was measured using the Paediatric Quality of Life Inventory 4.0 (ages 6-18 years). Functional ability was measured using the Childhood Health Assessment Questionnaire, and medical and sociodemographic parameters were assessed. The study sample was compared to a Dutch youth norm population including children with other chronic health conditions. The proportion of children with JIA with an impaired HRQOL (<1 SD) was evaluated and multivariate regression analyses were performed to predict HRQOL outcome. Results. Of the eligible patients, 64.1% (n = 152) participated. Both children (ages 6-12 years) and adolescents (ages 13-18 years) with JIA reported a significantly lower HRQOL in almost all domains compared to either healthy controls or children with other chronic health conditions. Approximately half of the children with JIA showed an impaired HRQOL. The main predictors of HRQOL were functional ability, pain, subjective burden of medication use, and school absence. Conclusion. The HRQOL is severely affected in children and adolescents with JIA. These findings underline the necessity to systematically monitor HRQOL in daily clinical practice. AN - WOS:000305790500007 AU - Haverman, L. AU - Grootenhuis, M. A. AU - van den Berg, J. M. AU - van Veenendaal, M. AU - Dolman, K. M. AU - Swart, J. F. AU - Kuijpers, T. W. AU - van Rossum, M. A. J. DA - May DO - 10.1002/acr.21609 IS - 5 N1 - Haverman, L. Grootenhuis, M. A. van den Berg, J. M. van Veenendaal, M. Dolman, K. M. Swart, J. F. Kuijpers, T. W. van Rossum, M. A. J. van den Berg, J.Merlijn/0000-0001-9431-5457 2151-4658 PY - 2012 SN - 2151-464X SP - 694-703 ST - Predictors of Health-Related Quality of Life in Children and Adolescents With Juvenile Idiopathic Arthritis: Results From a Web-Based Survey T2 - Arthritis Care & Research TI - Predictors of Health-Related Quality of Life in Children and Adolescents With Juvenile Idiopathic Arthritis: Results From a Web-Based Survey UR - ://WOS:000305790500007 VL - 64 ID - 2440 ER - TY - JOUR AB - BACKGROUND: There is a limited understanding of the patient and family experience of Chronic Transfusion Therapy (CTT) for prevention of complications of Sickle Cell Disease (SCD). We sought to understand patient and family experience with CTT using qualitative methods. METHODS: Fifteen parents of children < 18 years old and nine children 12-18 years old with SCD who were receiving CTT for > 1 year were interviewed using a semi-structured interview format, and interviews were analyzed using open coding methods. RESULTS: Four themes created a narrative of the patient and family experience of CTT: 1) Burden of CTT, 2) Coping with CTT, 3) Perceived benefits and risks of CTT, and 4) Decision making regarding CTT. Participants reported substantial burden of CTT, including the impact of CTT on daily life and family, distress about venous access, burden of chelation therapy, and anxiety about CTT complications. Participants described how they coped with CTT. Participants reported increased energy, decreased pain, fewer hospitalizations, and stroke prevention with CTT, but also recognized complications of CTT, though awareness was limited in adolescents. Parents described sharing in the informed decision-making process with their healthcare provider about CTT, but adolescent patient participants reported that they were not involved in this process. CONCLUSIONS: CTT is associated with significant patient and family burden. Support from family, healthcare providers and school may help individuals cope with some of this burden. These findings provide the basis for future studies to identify strategies to mitigate the burden of CTT and improve the patient experience with this therapy. Future studies should also systematically assess patient knowledge about the key components of CTT and chelation using quantitative assessments. AD - Emory University School of Medicine, Atlanta, GA, USA. Division of Pediatric Hematology-Oncology-BMT, Emory University School of Medicine, Atlanta, GA, USA. Aflac Cancer and Blood Disorders, Children's Healthcare of Atlanta, Atlanta, GA, USA. Division of Pediatric Hematology-Oncology-BMT, Emory University School of Medicine, Atlanta, GA, USA. nitya.bakshi@emory.edu. Aflac Cancer and Blood Disorders, Children's Healthcare of Atlanta, Atlanta, GA, USA. nitya.bakshi@emory.edu. AN - 32305060 AU - Hawkins, L. M. AU - Sinha, C. B. AU - Ross, D. AU - Yee, M. E. M. AU - Quarmyne, M. O. AU - Krishnamurti, L. AU - Bakshi, N. C2 - PMC7165370 DA - Apr 18 DO - 10.1186/s12887-020-02078-w DP - NLM ET - 2020/04/20 IS - 1 KW - Adolescent *Anemia, Sickle Cell/therapy Blood Transfusion Chelation Therapy Child Humans Parents Qualitative Research *Blood transfusion *Chronic transfusion *Qualitative *Quality of life *Sickle cell LA - eng N1 - 1471-2431 Hawkins, Lauren M Sinha, Cynthia B Ross, Diana Yee, Marianne E M Quarmyne, Maa-Ohui Krishnamurti, Lakshmanan Bakshi, Nitya K23 HL140142/HL/NHLBI NIH HHS/United States Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't BMC Pediatr. 2020 Apr 18;20(1):172. doi: 10.1186/s12887-020-02078-w. PY - 2020 SN - 1471-2431 SP - 172 ST - Patient and family experience with chronic transfusion therapy for sickle cell disease: A qualitative study T2 - BMC Pediatr TI - Patient and family experience with chronic transfusion therapy for sickle cell disease: A qualitative study VL - 20 ID - 3798 ER - TY - JOUR AB - Involving parents in children's pain management is essential to achieve optimal outcomes. Parents need to be equipped with sufficient knowledge and information. Only a limited number of studies have explored nurses' provision of parental guidance regarding the use of nonpharmacologic methods in children's pain management. This study aimed to examine nurses' perceptions of providing preparatory information and nonpharmacologic methods to parents, and how their demographics and perceived knowledge adequacy of these methods influence this guidance. A descriptive correlational study using questionnaire surveys was conducted to collect data from a convenience sample of 134 registered nurses working in seven pediatric wards of two public hospitals in Singapore. Descriptive statistics, independent-samples t test, and multiple linear regression were used to analyze the data. Most nurses provided various types of cognitive information to parents related to their children's surgery, whereas information about children's feelings was less often provided. Most nurses provided guidance to parents on positioning, breathing technique, comforting/reassurance, helping with activities of daily living, relaxation, and creating a comfortable environment. Nurses' provision of parental guidance on preparatory information and nonpharmacologic methods was significantly different between subgroups of age, education, parent or not, and perceived knowledge adequacy of nonpharmacologic methods. Nurses' perceived knowledge adequacy was the main factor influencing their provision of parental guidance. More attention should be paid to nurses who are younger, have less working experience, and are not parents. There is a need to educate nurses about nonpharmacologic pain relief methods to optimize their provision of parental guidance. (C) 2015 by the American Society for Pain Management Nursing AN - WOS:000347905800007 AU - He, H. G. AU - Klainin-Yobas, P. AU - Ang, E. N. K. AU - Sinnappan, R. AU - Polkki, T. AU - Wang, W. R. DA - Feb DO - 10.1016/j.pmn.2014.03.002 IS - 1 N1 - He, Hong-Gu Klainin-Yobas, Piyanee Ang, Emily Neo Kim Sinnappan, Rajammal Polkki, Tarja Wang, Wenru Wang, Wenru/N-1523-2019; Polkki, Tarja/I-8065-2015 Polkki, Tarja/0000-0002-8301-9537; Wang, Wenru/0000-0002-0265-8215 1532-8635 PY - 2015 SN - 1524-9042 SP - 40-50 ST - Nurses' Provision of Parental Guidance Regarding School-Aged Children's Postoperative Pain Management: A Descriptive Correlational Study T2 - Pain Management Nursing TI - Nurses' Provision of Parental Guidance Regarding School-Aged Children's Postoperative Pain Management: A Descriptive Correlational Study UR - ://WOS:000347905800007 VL - 16 ID - 2252 ER - TY - JOUR AB - Objective. This study aims to investigate the effectiveness of the "pain provocation technique" (PPT)-a focused treatment strategy incorporating interoceptive exposure (i.e., imagining increases in pain intensity), bilateral stimulation (tactile stimulation), and implementation of pain-related coping to decrease pain intensity-for adolescents suffering from chronic pain. Design. Prospective observational comparative study. Methods. Adolescents utilizing PPT (19 boys and 21 girls) within multimodal inpatient treatment were compared with adolescents in standard multimodal inpatient treatment matched for age, gender, and diagnosis. Core outcome variables (pain intensity, disability, emotional distress) were assessed at admission and 3 months posttreatment. Results. Adolescents in the PPT group demonstrated a sharper decrease in pain intensity and school aversion. Both groups demonstrated significant reductions in disability and emotional distress. Conclusions. Results are discussed in terms of the importance of focused treatment strategies such as interoceptive exposure for adolescents suffering from disabling chronic pain. Future studies are warranted to carefully investigate the effectiveness and possible process of change during the PPT such as sensory, cognitive, emotional, and memory aspects. AN - WOS:000278314200013 AU - Hechler, T. AU - Dobe, M. AU - Damschen, U. AU - Blankenburg, M. AU - Schroeder, S. AU - Kosfelder, J. AU - Zernikow, B. DO - 10.1111/j.1526-4637.2010.00839.x IS - 6 N1 - Hechler, Tanja Dobe, Michael Damschen, Uta Blankenburg, Markus Schroeder, Sandra Kosfelder, Joachim Zernikow, Boris 1526-4637 PY - 2010 SN - 1526-2375 SP - 897-910 ST - The Pain Provocation Technique for Adolescents with Chronic Pain: Preliminary Evidence for Its Effectiveness T2 - Pain Medicine TI - The Pain Provocation Technique for Adolescents with Chronic Pain: Preliminary Evidence for Its Effectiveness UR - ://WOS:000278314200013 VL - 11 ID - 2577 ER - TY - JOUR AB - Validated intruments for measuring coping in children and adolescents with chronic pain are rare in Germany. Using a sample of 180 out-patient children with chronic pain, a main component analysis was performed as well as cross-validations with out-patient and in-patient treated children. The scales of the PPCI-R showed significant relationships to pain characteristics and emotional stress. Different alterations were found in the PPCI-R scales in children with migraine and those with tension-type headache. The PPCI revised is therefore a validated instrument for measuring coping an can be implemented e.g. in treatment studies for children suffering from chronic pain. AD - Vodafone-Stiftungsinstitut für Kinderschmerztherapie und pädiatrische Palliativmedizin, Vestische Kinder- und Jugendklinik,Universität Witten/Herdecke, Dr.-Friedrich-Steiner-Str. 5, 45711, Datteln, Deutschland. T.Hechler@kinderklinik-datteln.de AN - 18297316 AU - Hechler, T. AU - Kosfelder, J. AU - Denecke, H. AU - Dobe, M. AU - Hübner, B. AU - Martin, A. AU - Menke, A. AU - Schroeder, S. AU - Marbach, S. AU - Zernikow, B. DA - Aug DO - 10.1007/s00482-008-0621-4 DP - NLM ET - 2008/02/26 IS - 4 KW - Absenteeism *Adaptation, Psychological Adolescent Ambulatory Care Child Child, Preschool Chronic Disease Female Humans Male Migraine Disorders/psychology Pain/*psychology Pain Management Pain Measurement Patient Admission Personality Inventory/*statistics & numerical data Psychometrics/statistics & numerical data Reproducibility of Results *Sick Role Tension-Type Headache/psychology LA - ger N1 - Hechler, T Kosfelder, J Denecke, H Dobe, M Hübner, B Martin, A Menke, A Schroeder, S Marbach, S Zernikow, B English Abstract Journal Article Germany Schmerz. 2008 Aug;22(4):442-57. doi: 10.1007/s00482-008-0621-4. OP - Schmerzbezogene Copingstrategien von Kindern und Jugendlichen mit chronischen Schmerzen. Uberprüfung einer deutschen Fassung der Paediatric Pain Coping Inventory (PPCI-revised). PY - 2008 SN - 0932-433X (Print) 0932-433x SP - 442-57 ST - [Pain-related coping strategies in children and adolescents with chronic pain. Validation of a German version of the Paediatric Pain Coping Inventory (PPCI revised)] T2 - Schmerz TI - [Pain-related coping strategies in children and adolescents with chronic pain. Validation of a German version of the Paediatric Pain Coping Inventory (PPCI revised)] VL - 22 ID - 3421 ER - TY - JOUR AB - Background/Aims: The purpose of this study was to correlate imaging and sialendoscopic findings to therapeutic response in patients with idiopathic chronic parotitis. Methods: We retrospectively reviewed 122 consecutive sialendoscopies performed in an academic medical center by two surgeons between 2008 and 2013. Forty-one (34%) and 54 (44%) patients were excluded on the basis of having parotid or submandibular sialolith, respectively. Nineteen cases were included in the study with idiopathic chronic parotitis. There was a median follow-up of 5 months. Results: Computed tomography (CT) imaging had a sensitivity and specificity of 80.0 and 71.4%, respectively, for predicting abnormal findings on sialendoscopy, while magnetic resonance imaging (MRI) had 100% accuracy in a small set of cases. In glands with noticeable pathology present on preoperative imaging or sialendoscopy, 11 out of 12 glands (92%) treated experienced symptomatic improvement, while 3 out of 7 glands (43%) without pathology on imaging or endoscopy experienced symptomatic improvement (p = 0.038). Conclusions: Sialendoscopy for the treatment of idiopathic chronic parotid disease can improve pain and swelling with a higher frequency of success in patients with abnormalities noted on endoscopy. CT and MRI have a moderate degree of accuracy in predicting which patients will benefit from therapeutic sialendoscopy. (C) 2015 S. Karger AG, Basel AN - WOS:000362700000008 AU - Heineman, T. E. AU - Kacker, A. AU - Kutler, D. I. DO - 10.1159/000438760 IS - 5 N1 - Heineman, Thomas E. Kacker, Ashutosh Kutler, David I. 1423-0275 PY - 2015 SN - 0301-1569 SP - 302-309 ST - Idiopathic Chronic Parotitis: Imaging Findings and Sialendoscopic Response T2 - Orl-Journal for Oto-Rhino-Laryngology Head and Neck Surgery TI - Idiopathic Chronic Parotitis: Imaging Findings and Sialendoscopic Response UR - ://WOS:000362700000008 VL - 77 ID - 2255 ER - TY - JOUR AB - BACKGROUND: Adolescents are routinely recognized as native to online technologies. However, we know from previous research that this familiarity does not often translate into its use for help-seeking around health. We designed this study to examine the experience of adolescents in using the Internet to access pain management information, specifically why some adolescents may be reluctant to use these resources. METHODS: Twenty-six healthy, school attending, adolescents aged between 14 and 17 years old were recruited to a qualitative study of focus groups. Seventeen participants were female and nine were male. Participation was limited to those who self-selected as frequent users of the Internet, but who were loath to use it as a resource for health information as we wished to explore reasons for non-use. All data were thematically analysed. RESULTS: Most participants reported using the Internet to seek health information at least once. Experiences with online content were typically negative and drawn on only when all other sources of information and pain coping were exhausted. Three themes emerged, Drivers of Internet use, Barriers, and Anxiety around use. Adolescent health websites were reported to be confusing, anxiety provoking and hard to negotiate. The Internet was judged to be less accessible than other forms of pain and health coping information. Secondary themes related to topic embarrassment, the strive for independence and reassurance, preferred information source failure, curiosity, website design, availability of OTC analgesics, effort, fear-provoking narratives, mistrust of quality of online content and pain-related anxiety. CONCLUSIONS: Counter to many positive reports of the health benefits of Internet use during information seeking, its value is questionable to some adolescents. Typical experience was anxiety provoking, unlikely to yield helpful results, and wasteful comparative to off-line resources for pain. AD - Centre for Pain Research, The University of Bath, Bath, UK. AN - 23663232 AU - Henderson, E. M. AU - Keogh, E. AU - Eccleston, C. DA - Jul DO - 10.1111/cch.12072 DP - NLM ET - 2013/05/15 IS - 4 KW - Adolescent Adolescent Behavior Consumer Health Information England/epidemiology Female Health Behavior Health Knowledge, Attitudes, Practice Humans *Information Seeking Behavior *Internet/statistics & numerical data Male Pain/*psychology Qualitative Research Quality of Health Care Self Care/*psychology/statistics & numerical data Surveys and Questionnaires Internet bias information seeking pain management LA - eng N1 - 1365-2214 Henderson, E M Keogh, E Eccleston, C Journal Article Multicenter Study Research Support, Non-U.S. Gov't England Child Care Health Dev. 2014 Jul;40(4):572-9. doi: 10.1111/cch.12072. Epub 2013 May 12. PY - 2014 SN - 0305-1862 SP - 572-9 ST - Why go online when you have pain? A qualitative analysis of teenagers' use of the Internet for pain management advice T2 - Child Care Health Dev TI - Why go online when you have pain? A qualitative analysis of teenagers' use of the Internet for pain management advice VL - 40 ID - 4112 ER - TY - JOUR AB - OBJECTIVES: To explore a community sample of adolescents for engagement with online pain resources. To assess if the use of the Internet to search for health information correlated with measures of coping, risk taking, catastrophizing about pain, and engaging in the self-management of pain. DESIGN: A cross-sectional online study of community-based adolescents (n = 105) recruited via schools to examine their use of the Internet to seek pain-related information. METHODS: Adolescents completed questionnaires of pain coping, catastrophic thinking, risk-taking behaviour, and medication use. Descriptive analyses were undertaken on event rates of pertinent behaviours, principally on information seeking and pain management behaviour. Correlational analyses were undertaken between coping and information seeking, and medication use. RESULTS: Few participants engaged in online pain information seeking. Those who did were more likely to be female and scored higher on medication use, catastrophizing, risk taking, and the total score on the Pain Coping Questionnaire. CONCLUSIONS: Although adolescents are high users of the Internet, paradoxically they do not appear to use the Internet for information about pain and pain management. Further research should assess inhibitory and disinhibitory factors associated with information seeking about pain and chronic illness on the Internet. STATEMENT OF CONTRIBUTION: What is already known on this subject? Internet use in adolescents is common, mobile, and displays a level of technical awareness unparalleled by adults. The internet is postulated in previous research to present a platform for the delivery of health care, particularly information to aid health decision-making for young people. What does this study add? This study explores how adolescents use the internet to look for health information, particularly on pain and where this falls in a general profile of coping with illness. Interestingly and counterintuitively, adolescents did not use the internet to look for health or pain information. We hypothesize that there may be something about information on pain management that does not readily transfer to the digital world in a way that is useful to adolescent users. AD - Centre for Pain Research, University of Bath, UK. AN - 23126577 AU - Henderson, E. M. AU - Keogh, E. AU - Rosser, B. A. AU - Eccleston, C. DA - Feb DO - 10.1111/bjhp.12005 DP - NLM ET - 2012/11/07 IS - 1 KW - *Adaptation, Psychological Adolescent Adolescent Behavior/psychology Child Cross-Sectional Studies England Female *Health Behavior *Health Knowledge, Attitudes, Practice Humans *Internet Male Pain/psychology Pain Management/*methods/*psychology Risk-Taking Self Care/methods/psychology Surveys and Questionnaires LA - eng N1 - 2044-8287 Henderson, Ellen M Keogh, Edmund Rosser, Benjamin A Eccleston, Christopher Journal Article England Br J Health Psychol. 2013 Feb;18(1):218-32. doi: 10.1111/bjhp.12005. Epub 2012 Nov 6. PY - 2013 SN - 1359-107x SP - 218-32 ST - Searching the internet for help with pain: adolescent search, coping, and medication behaviour T2 - Br J Health Psychol TI - Searching the internet for help with pain: adolescent search, coping, and medication behaviour VL - 18 ID - 3230 ER - TY - JOUR AB - While animal studies suggest that neonatal pain experiences induce long-term alterations in pain sensitivity, no such data exist in humans. Changes in pain sensitivity in school-aged children (9-14 years) who were born preterm or fullterm, had been hospitalized for a prolonged period of time after birth and had undergone repeated painful procedures while being treated in a Neonatal Intensive Care Unit (NICU) were determined. A retrospective cohort study of 19 preterm (or=37 weeks gestational age) treated at least 3 days in a NICU at a University Hospital and 20 fullterm control children without NICU experience was performed. Perceptual sensitization to tonic heat and repetitive mechanical stimuli as well as heat pain and mechanical pain thresholds were obtained at the thenar and a trigeminal site. Length of hospitalization and NICU treatment was significantly higher in preterm than fullterm children. Nonetheless, both preterm and fullterm children with NICU experience showed greater perceptual sensitization to tonic heat and elevated heat pain thresholds at both sites. Mechanical pain threshold and perceptual sensitization did not differ between groups. Consistent with findings in animals, repeated pain experiences during the neonatal period were associated with alterations in thermal pain responsivity in school-aged preterm and fullterm children that was characterized by enhanced perceptual sensitization to prolonged painful stimulation and hypoalgesia to brief heat pain stimuli. Our findings suggest that repeated pain experiences in neonates may induce activity-induced changes in the functioning of pain pathways that persist well beyond infancy. AU - Hermann, Christiane AU - Hohmeister, Johanna AU - Demirakça, Sueha AU - Zohsel, Katrin AU - Flor, Herta DA - 2006/12/05/ DO - 10.1016/j.pain.2006.08.026 DP - PubMed IS - 3 J2 - Pain KW - Adaptation, Physiological Adolescent Aging Child Cohort Studies Female Humans Longitudinal Studies Male Pain Pain Measurement Pain Threshold Retrospective Studies LA - eng PY - 2006 SN - 1872-6623 SP - 278-285 ST - Long-term alteration of pain sensitivity in school-aged children with early pain experiences T2 - Pain TI - Long-term alteration of pain sensitivity in school-aged children with early pain experiences UR - http://www.ncbi.nlm.nih.gov/pubmed/17011707 VL - 125 ID - 117 ER - TY - JOUR AB - Pain coping and pain-related cognitions are considered important for the understanding of chronic pain in children. Based on a systematic literature search, 4 instruments were identified that assess a range of pain coping strategies and one questionnaire focusing on pain-related cognitions. Three of these tools have good psychometric quality. Yet, only the Pain Coping Questionnaire (PCQ) has been widely used across different pain conditions and by several international research groups. We designed the Pain-Related Cognitions Questionnaire for Children (PRCQ-C) as an abbreviated German version of the PCQ. Factorial, construct, and external validity were tested in a sample of 401 children and adolescents (7-18 years) comprising 253 school children and 148 children having recurrent pain. The proposed 3 subscales, "catastrophizing," "problem-solving," and "positive self-statements," were confirmed, all having good internal consistency and retest reliability. No age and only marginal gender differences were observed. Catastrophizing was associated with dysphoric mood, trait anxiety, and current pain activity. Subgroups of pain patients differed with regard to catastrophizing and positive self-statements. PERSPECTIVE: The PRCQ-C is a brief instrument for the assessment of pain-related cognitions in children and adolescents. It supports the validity of the PCQ, demonstrates its use in an abbreviated version and extends its international availability. AD - Department of Clinical and Cognitive Neuroscience, University of Heidelberg, Central Institute of Mental Health, Mannheim, Germany. christiane.hermann@zi-mannheim.de AN - 17631054 AU - Hermann, C. AU - Hohmeister, J. AU - Zohsel, K. AU - Ebinger, F. AU - Flor, H. DA - Oct DO - 10.1016/j.jpain.2007.05.010 DP - NLM ET - 2007/07/17 IS - 10 KW - *Adaptation, Psychological Adolescent Age Factors Child Chronic Disease Female Humans Male Pain/*psychology Pain Measurement/*methods Reproducibility of Results Sex Factors Surveys and Questionnaires LA - eng N1 - Hermann, Christiane Hohmeister, Johanna Zohsel, Katrin Ebinger, Friedrich Flor, Herta Journal Article Research Support, Non-U.S. Gov't United States J Pain. 2007 Oct;8(10):802-13. doi: 10.1016/j.jpain.2007.05.010. Epub 2007 Jul 12. PY - 2007 SN - 1526-5900 (Print) 1526-5900 SP - 802-13 ST - The assessment of pain coping and pain-related cognitions in children and adolescents: current methods and further development T2 - J Pain TI - The assessment of pain coping and pain-related cognitions in children and adolescents: current methods and further development VL - 8 ID - 3279 ER - TY - JOUR AB - Considerable discussion in child sexual abuse evaluation centers around minimizing the number of victim interviews, however, the completeness of one professional's interview is not always addressed. In this study, professionals (medical, social, law enforcement/legal, mental health) indicated what components they included in their interviews of sexual abuse victims and their parents. Components included: details of abuse, family relationships, school situation/performance, child's development (toilet training, bed wetting, language development, etc.), child's knowledge of body part names, child's knowledge of body part functions, child-rearing practices (bathing, sleeping), medical history (illnesses, surgery), behavior problems, psychological symptoms (nightmares, sadness), physical complaints (pain, discharge), parental teaching about sex, and child's access to sexually explicit television or magazines. Interview components varied by profession, consistent with expected professional bias. This study demonstrates some professional bias in interviewing children and parents and suggests that having a single interview or interviewer may not always be optimal for a thorough evaluation. Increased communication and teamwork among professionals, and cross-training among disciplines could facilitate both the recognition of appropriateness of some ''multiple interviews'' as well as provide efforts to consolidate interviews when possible. AN - WOS:A1993LQ40200006 AU - Hibbard, R. A. AU - Hartman, G. L. DA - Jul-Aug DO - 10.1016/0145-2134(93)90024-y IS - 4 N1 - Hibbard, ra hartman, gl PY - 1993 SN - 0145-2134 SP - 495-500 ST - COMPONENTS OF CHILD AND PARENT INTERVIEWS IN CASES OF ALLEGED SEXUAL ABUSE T2 - Child Abuse & Neglect TI - COMPONENTS OF CHILD AND PARENT INTERVIEWS IN CASES OF ALLEGED SEXUAL ABUSE UR - ://WOS:A1993LQ40200006 VL - 17 ID - 2953 ER - TY - CHAP A2 - Sultan, C. AB - Chronic pelvic pain occurs commonly in the adolescent and can be a diagnostic and therapeutic challenge for the clinician, the adolescent, and her family. Defined as lower quadrant or lower abdominal pain lasting 3-6 months or longer, chronic pelvic pain can lead to missed school and activities, decreased functioning, and decreased quality of life in the adolescent. Both the primary care clinician and the pediatric gynecologist need to be aware of the most common causes of chronic pelvic pain in the adolescent, including surgical and nonsurgical, gynecologic versus other pathology including the psychosomatic, and the role of the mind in control of somatic pain in the adolescent. Adding to this complexity is the standard adolescent sense of invulnerability; a knowledge of adolescent development remains essential to the delivery of appropriate gynecologic care for this age group. Education and communication with both the adolescent and her family requires sensitivity, especially in cultures where adolescent sexuality is taboo or discouraged. This chapter will discuss the developmental stages of adolescence and how that impacts care of the patient with chronic pelvic pain at the varying ages, the issue of confidentiality when obtaining a sexual history on the adolescent, and etiologies of chronic pelvic pain specific to the adolescent, including gynecologic and nongynecologic causes. Diagnostic and treatment considerations for chronic pelvic pain in the adolescent will also be addressed. Copyright (C) 2012 S. Karger AG, Basel AN - WOS:000310771800017 AU - Hicks, C. W. AU - Rome, E. S. N1 - Hicks, Caitlin W. Rome, Ellen S. Hicks, Caitlin/0000-0001-7638-1936 1421-7082 PY - 2012 SN - 978-3-8055-9336-6 SP - 230-250 ST - Chronic Pelvic Pain in the Adolescent T2 - Pediatric and Adolescent Gynecology: Evidence-Based Clinical Practice, 2nd Edition T3 - Endocrine Development TI - Chronic Pelvic Pain in the Adolescent UR - ://WOS:000310771800017 VL - 22 ID - 2454 ER - TY - JOUR AB - OBJECTIVE: Chronic pain is a significant concern for the Veterans Health Administration (VHA), with chronic pain conditions among those most frequently reported by Operation Enduring Freedom (OEF)/Operation Iraqi Freedom (OIF)/Operation New Dawn (OND) veterans. The current study examined VHA electronic medical record data to examine variation in demographics and high prevalence and high impact medical and mental health conditions in order to characterize the differences between patients with persistent pain and no pain. DESIGN: A conservative operational definition of chronic or "persistent pain" based on multiple indicators of pain (i.e., pain intensity ratings, prescription opioids, pain clinic visits, International Classification of Diseases, Ninth Revision codes) was employed. Analyses included the entire roster of longitudinal clinical data on OEF/OIF/OND veterans who used VHA care to compare those with persistent pain with those with no clinical evidence of pain. RESULTS: Results of logistic regression models suggest that sex, race, education, military variables, body mass index (BMI), traumatic brain injury (TBI), and mental health conditions, but not age, reliably discriminate the two groups. Those with persistent pain were more likely to be Black, female, on active duty, enlisted, Army service members, have a high school education or less, and have diagnoses of mood disorders, post-traumatic stress disorder, substance use disorders, anxiety disorders, TBI, and have a BMI consistent with overweight and obesity. CONCLUSIONS: The operational definition of chronic pain used in this study may have research implications for examining predictors of incident and chronic pain. These data have important clinical implications in that addressing comorbid conditions of persistent pain may improve adaptive coping and functioning in these patients. AD - Psychiatry, VA Boston Healthcare System, Boston, Massachusetts, USA; School of Medicine, Boston University, Boston, Massachusetts, USA. AN - 24548466 AU - Higgins, D. M. AU - Kerns, R. D. AU - Brandt, C. A. AU - Haskell, S. G. AU - Bathulapalli, H. AU - Gilliam, W. AU - Goulet, J. L. DA - May DO - 10.1111/pme.12388 DP - NLM ET - 2014/02/20 IS - 5 KW - Adult Afghan Campaign 2001- Chronic Pain/*epidemiology Comorbidity Depressive Disorder/*epidemiology Female Humans Iraq War, 2003-2011 Logistic Models Longitudinal Studies Male Middle Aged Multivariate Analysis Obesity/*epidemiology Prevalence Stress Disorders, Post-Traumatic/*epidemiology Substance-Related Disorders/*epidemiology United States/epidemiology United States Department of Veterans Affairs Veterans/*statistics & numerical data Anxiety Depression Obesity Pain Management Persistent Pain Post-traumatic Stress Syndrome Substance Abuse LA - eng N1 - 1526-4637 Higgins, Diana M Kerns, Robert D Brandt, Cynthia A Haskell, Sally G Bathulapalli, Harini Gilliam, Wesley Goulet, Joseph L I01 HX000915/HX/HSRD VA/United States Journal Article Research Support, U.S. Gov't, Non-P.H.S. England Pain Med. 2014 May;15(5):782-90. doi: 10.1111/pme.12388. Epub 2014 Feb 18. PY - 2014 SN - 1526-2375 SP - 782-90 ST - Persistent pain and comorbidity among Operation Enduring Freedom/Operation Iraqi Freedom/operation New Dawn veterans T2 - Pain Med TI - Persistent pain and comorbidity among Operation Enduring Freedom/Operation Iraqi Freedom/operation New Dawn veterans VL - 15 ID - 3531 ER - TY - JOUR AB - Background: Chronic pain impacts 15%-20% of U.S. children. Integrative medicine (IM) services, including acupuncture, are used in many children's hospitals and pain clinics to address complex chronic-pain syndromes. However, few facilities specifically address chronic pain in underserved pediatric populations. Objective: The aim of this article is describe the process of establishing an integrative pediatric pain clinic that includes acupuncture therapy in a children's hospital, and to report acupuncture utilization during the first 6 months. Methods: A needs assessment was conducted, and its findings led to the assembly of an interdisciplinary integrative team and the establishment of the Pediatric Pain Clinic. Experience from an existing program for IM provided the infrastructure and model for the Pediatric Pain Clinic. Results: Thirty-six referrals were received, 26 patients underwent initial evaluations, 23 returned for follow-up visits, and 3 have "graduated'' pain-free. Nineteen of the 26 patients received acupuncture/acupressure. Conclusions: A pediatric pain clinic that consists of interdisciplinary biomedical and integrative modalities, including acupuncture, can be successfully established in a safety-net hospital for children with complex pain. The success of an already-existing pediatric acupuncture service within an IM program helped to incorporate acupuncture seamlessly into the hospital's new Pediatric Pain Clinic. AN - WOS:000217806700007 AU - Highfield, E. S. AU - Broderick, M. AU - Goldstein, L. AU - Dickman, L. AU - Neri, C. M. DA - Dec DO - 10.1089/acu.2015.1141 IS - 6 N1 - Highfield, Ellen Silver Broderick, Maria Goldstein, Laura Dickman, Laura Neri, Caitlin M. 1933-6594 Si PY - 2015 SN - 1933-6586 SP - 437-441 ST - Acupuncture as Part of a Pediatric Pain Clinic in a Safety-Net Hospital: Acupuncture Wednesday T2 - Medical Acupuncture TI - Acupuncture as Part of a Pediatric Pain Clinic in a Safety-Net Hospital: Acupuncture Wednesday UR - ://WOS:000217806700007 VL - 27 ID - 2206 ER - TY - JOUR AB - OBJECTIVES: Medical follow-up in the most appropriate treatment setting is important for patients with juvenile idiopathic arthritis (JIA). The aims of this study were 1) to identify the settings in which JIA patients are followed up after leaving paediatric rheumatology, and 2) to compare the clinical profile of patients in different settings. METHODS: The Short Form-36, Health Assessment Questionnaire, and linear analogue scale for quality of life were sent to JIA patients older than 16 years, who had been followed in one academic paediatric rheumatology centre from 1994 to 2007 and who did not participate in a structured transitional care program. Forty-four patients participated in this cross-sectional, comparative study. RESULTS: Thirteen patients were no longer in medical follow-up, 6 patients were followed by their general practitioner, and 25 patients were followed by a rheumatologist. All patients treated with glucocorticosteroids, DMARDs and anti-TNF were followed by a rheumatologist. Patients under the care of a rheumatologist had worse physical functioning (U=33.5, p<0.001); greater disability (U=49.0, p=0.001); more pain (U=59.0, p=0.002); and lower quality of life (U=69, p=0.02) than patients not in follow-up. Of the patients no longer in follow-up, 2 (16.7%) had disabilities and 5 (41.7%) reported persistent pain. CONCLUSIONS: The present data indicated that JIA patients with persistent disease and associated functional disabilities tend to remain in the rheumatology circuit. However, the disease of patients leaving specialised rheumatology care is not necessarily controlled. These data may be helpful for organising the proper transfer of patients from paediatric to adult-focused care. AD - Center for Health Services and Nursing Research, Katholieke Universiteit Leuven, Leuven, Belgium. deborah.hilderson@med.kuleuven.be AN - 20863450 AU - Hilderson, D. AU - Corstjens, F. AU - Moons, P. AU - Wouters, C. AU - Westhovens, R. DA - Sep-Oct DP - NLM ET - 2010/09/25 IS - 5 KW - Adolescent *Adolescent Medicine Adult Age Factors Arthritis, Juvenile/epidemiology/physiopathology/*rehabilitation Belgium/epidemiology Comorbidity Cross-Sectional Studies Disability Evaluation Female Follow-Up Studies Health Status Humans Male Pain/epidemiology/physiopathology *Patient Care Management Prognosis Quality of Life Recovery of Function Remission Induction Severity of Illness Index Young Adult LA - eng N1 - Hilderson, D Corstjens, F Moons, P Wouters, C Westhovens, R Comparative Study Journal Article Italy Clin Exp Rheumatol. 2010 Sep-Oct;28(5):790-7. Epub 2010 Oct 22. PY - 2010 SN - 0392-856X (Print) 0392-856x SP - 790-7 ST - Adolescents with juvenile idiopathic arthritis: who cares after the age of 16? T2 - Clin Exp Rheumatol TI - Adolescents with juvenile idiopathic arthritis: who cares after the age of 16? VL - 28 ID - 4094 ER - TY - JOUR AB - BACKGROUND: Patients with depression have irritable bowel syndrome (IBS) more often than do nondepressed patients, but the comorbidity of depression and gastrointestinal (GI) symptoms in the general population has received little study. AIM: To study the co-occurrence of depressive and GI symptoms in a general population sample and to assess the rate of health-care utilization particularly for GI reasons among subjects with depressive symptoms. METHODS: A questionnaire containing the Finnish version of the Beck Depression Inventory Short Form and questions covering GI symptoms according to Rome II criteria was mailed to 5000 randomly selected adults. RESULTS: Response rate was 73%. Prevalence of depressive symptoms was 17% (95% CI: 15.7-18.2). Frequent abdominal pain, diarrhoea, constipation, dyspepsia or IBS were present in 54% of those with depressive symptoms and in 29% of nondepressed controls (P < 0.0001). Of those with depressive symptoms, 24% had visited a physician at least once because of abdominal symptoms during the previous year, compared to 13% of controls (P < 0.0001). CONCLUSIONS: Depressive symptoms are prevalent in the general population. They are associated with a high rate of GI symptoms, leading to increased use of health-care services and work absenteeism because of abdominal complaints. AD - Division of Gastroenterology, Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland. markku.hillila@hus.fi AN - 18564324 AU - Hillilä, M. T. AU - Hämäläinen, J. AU - Heikkinen, M. E. AU - Färkkilä, M. A. DA - Sep 1 DO - 10.1111/j.1365-2036.2008.03771.x DP - NLM ET - 2008/06/20 IS - 5 KW - Adolescent Adult Cross-Sectional Studies Depressive Disorder/*complications/epidemiology Female Health Surveys Humans Irritable Bowel Syndrome/epidemiology/*psychology Logistic Models Male Middle Aged *Patient Acceptance of Health Care Psychiatric Status Rating Scales Quality of Life/*psychology Risk Factors Surveys and Questionnaires LA - eng N1 - 1365-2036 Hillilä, M T Hämäläinen, J Heikkinen, M E Färkkilä, M A Journal Article Research Support, Non-U.S. Gov't England Aliment Pharmacol Ther. 2008 Sep 1;28(5):648-54. doi: 10.1111/j.1365-2036.2008.03771.x. Epub 2008 Jun 28. PY - 2008 SN - 0269-2813 SP - 648-54 ST - Gastrointestinal complaints among subjects with depressive symptoms in the general population T2 - Aliment Pharmacol Ther TI - Gastrointestinal complaints among subjects with depressive symptoms in the general population VL - 28 ID - 4124 ER - TY - JOUR AB - Background This study aimed to determine the prevalence oi-psychiatric disorder in young adults with homzygous sickle cell (SS) disease and in controls with normal haemoglobin, and to examine factors associated with psychiatric disorder. Method The study design was cross-sectional. Subjects were aged 18-20 years: 63 with SS disease and 89 controls. The Psychiatric Assessment Schedule was used to determine psychiatric disorder at Index of Definition level 5. Results Psychiatric disorder was identified in 18 (29%) SS disease patients and in 22 (25%) controls. in SS patients, psychiatric disorder was not related to illness severity but was associated with leaving school early, difficulties in social adjustment, impaired cognitive function and having previous psychiatric difficulties. Male SS patients with psychiatric disorder all had low body mass index (BMI < 17.60). In controls, psychiatric disorder was associated with female gender, unemployment and difficulties in social adjustment. Conclusions The prevalence of psychiatric disorder was similar in patients and controls, although associated factors tended to be different. The association with low BMI in SS men merits further study. AN - WOS:A1997WF67100015 AU - Hilton, C. AU - Osborn, M. AU - Knight, S. AU - Singhal, A. AU - Serjeant, G. DA - Jan DO - 10.1192/bjp.170.1.69 N1 - Hilton, C Osborn, M Knight, S Singhal, A Serjeant, G 1472-1465 PY - 1997 SN - 0007-1250 SP - 69-76 ST - Psychiatric complications of homozygous sickle cell disease among young adults in the Jamaican Cohort Study T2 - British Journal of Psychiatry TI - Psychiatric complications of homozygous sickle cell disease among young adults in the Jamaican Cohort Study UR - ://WOS:A1997WF67100015 VL - 170 ID - 2915 ER - TY - JOUR AB - Children and young people frequently report physical complaints that have no observable physical pathology known as medically unexplained symptoms (MUS). Research suggests that MUS are associated with substantial physical and psychological impairments and may have a negative impact on children's and young people's functional status and well-being in the long term. Due to the potentially complex needs of this group, children and young people with MUS may require timely access to suitable health and social care services to effectively manage symptoms and achieve their academic, social and personal potential. Families and professionals can offer important insights into the availability and appropriateness of current community and specialist health and social care services. This review is the first critical evaluation and synthesis of research that has examined families' and healthcare professionals' (HCP) perceptions of healthcare services for children and young people with MUS. A systematic search of electronic databases and manual searches of key journals and reference lists identified 17 papers from 15 studies for inclusion in the review. The review highlights the paucity of rigorously conducted research on this topic. Studies have been narrowly focused on the views of a homogeneous group of mothers and young people attending single centres. There has been some attempt to examine doctors' views, but the perceptions of children, fathers and health and social care professionals are absent or under-represented, and multi-site and longitudinal studies are lacking. Thematic analysis of the results from the included studies suggests that knowledge, communication, health beliefs and healthcare settings are factors that influence families' and HCPs' perceptions of services. Families report dissatisfaction with some HCPs' approach to managing MUS. The findings suggest that children and young people with MUS are at risk of receiving suboptimal care and support because there is insufficient research to inform high-quality, evidence-based practice. AN - WOS:000368724200002 AU - Hinton, D. AU - Kirk, S. DA - Jan DO - 10.1111/hsc.12184 IS - 1 N1 - Hinton, Denise Kirk, Susan Kirk, Susan/0000-0002-1485-8804 1365-2524 PY - 2016 SN - 0966-0410 SP - 12-26 ST - Families' and healthcare professionals' perceptions of healthcare services for children and young people with medically unexplained symptoms: anarrative review of the literature T2 - Health & Social Care in the Community TI - Families' and healthcare professionals' perceptions of healthcare services for children and young people with medically unexplained symptoms: anarrative review of the literature UR - ://WOS:000368724200002 VL - 24 ID - 2198 ER - TY - JOUR AB - Children's strategies for coping with the pain and distress of venipuncture were examined in this descriptive study. Eighty-five children (aged 5-13 years) were interviewed prior to and following blood collection. Prior to the procedure, children reported pain expectations and coping strategies that might be used. Self-reports of the pain experienced and coping strategies used were obtained immediately after the procedure. Twenty-seven different strategies were identified from the children's responses. These strategies were subsequently grouped into 11 coping categories: Active Involvement in Procedure, Behavior-Regulating Cognitions, Cognitive Reappraisal, Direct Efforts to Maintain Control, Diversionary Thinking, Emotion-Regulating Cognitions, Information Seeking, Reality-Oriented Working Through, Reliance on Health-Care Interventions, Support Seeking and Avoidance and Catastrophizing. Direct Efforts to Maintain Control was the most frequently used category. Age and gender differences were observed in both number and type of strategies reported by the children. Further research is needed to examine the observed relationship between the type of coping strategies generated and the children's pain experience. (C) U.S. Cancer Pain Relief Committee, 1997. AN - WOS:A1997XB84100011 AU - Hodgins, M. J. AU - Lander, J. DA - May DO - 10.1016/s0885-3924(96)00328-4 IS - 5 N1 - Hodgins, MJ Lander, J PY - 1997 SN - 0885-3924 SP - 274-285 ST - Children's coping with venipuncture T2 - Journal of Pain and Symptom Management TI - Children's coping with venipuncture UR - ://WOS:A1997XB84100011 VL - 13 ID - 2910 ER - TY - JOUR AB - Zusammenfassung Als chronische Schmerzsyndrome im Kindes- und Jugendalter werden kontinuierliche Schmerzen uber einen Zeitraum von mindestens 3 Monaten bezeichnet. Mittlerweile ist schatzungsweise jedes vierte Kind in Deutschland betroffen. Jedes zwanzigste leidet extrem stark unter den immer wiederkehrenden Schmerzen. Neben Kopf- und Bauchschmerzen werden verstarkt muskuloskelettale Schmerzen beobachtet, welche in ihrer Lokalisation, Intensitat, Qualitat und Haufigkeit fluktuieren. Aufgrund der Schmerzen, Schonhaltungen und psychologischen Einflussfaktoren wie Angste oder Traurigkeit kommt es zu einer zunehmenden Verschlechterung der Lebensqualitat, da im Verlauf z.B. Schulbesuch, soziale Aktivitaten und Hobbys reduziert werden. Diese ubersicht stellt die Hintergrunde dieser chronischen Erkrankung und eine multimodale, therapeutische Herangehensweise vor, wie sie am Zentrum fur Schmerztherapie / Garmisch-Partenkirchen durchgefuhrt wird. Abstract Chronic pain syndromes in children and adolescents are defined as constant pain over a period of 3 months or more. They are currently estimated to affect every fourth child in Germany, with every twentieth suffering extremely from the recurring pain. Besides headache and abdominal pain, musculoskeletal pain is increasingly reported, fluctuating in localisation, intensity, quality and frequency. Due to pain, antalgic postures and psychological factors such as fear and sadness, patients' quality of life declines as school attendance, social activities and hobbies are reduced over time. This review summarises the background of this chronic illness and introduces a multimodal therapeutic approach, which is implemented at the Centre of Pain Therapy in Garmisch-Partenkirchen. AN - WOS:000383566200017 AU - Hoefel, L. AU - Spamer, M. AU - Haefner, R. AU - Draheim, N. AU - Schnoebel-Mueller, E. AU - Haas, J. P. DA - Aug DO - 10.1055/s-0042-105741 IS - 4 N1 - Hoefel, L. Spamer, M. Haefner, R. Draheim, N. Schnoebel-Mueller, E. Haas, J. -P. 1438-9940 PY - 2016 SN - 0341-051X SP - 326-333 ST - Multimodal Treatment of Chronic Musculoskeletal Pain in Children and Adolescents T2 - Aktuelle Rheumatologie TI - Multimodal Treatment of Chronic Musculoskeletal Pain in Children and Adolescents UR - ://WOS:000383566200017 VL - 41 ID - 2151 ER - TY - JOUR AB - OBJECTIVES: To estimate annual medical and nonmedical costs of care for children diagnosed with irritable bowel syndrome (IBS) or functional abdominal pain (syndrome; FAP/FAPS). STUDY DESIGN: Baseline data from children with IBS or FAP/FAPS who were included in a multicenter trial (NTR2725) in The Netherlands were analyzed. Patients' parents completed a questionnaire concerning usage of healthcare resources, travel costs, out-of-pocket expenses, productivity loss of parents, and supportive measures at school. Use of abdominal pain related prescription medication was derived from case reports forms. Total annual costs per patient were calculated as the sum of direct and indirect medical and nonmedical costs. Costs of initial diagnostic investigations were not included. RESULTS: A total of 258 children, mean age 13.4 years (±5.5), were included, and 183 (70.9%) were female. Total annual costs per patient were estimated to be €2512.31. Inpatient and outpatient healthcare use were major cost drivers, accounting for 22.5% and 35.2% of total annual costs, respectively. Parental productivity loss accounted for 22.2% of total annual costs. No difference was found in total costs between children with IBS or FAP/FAPS. CONCLUSIONS: Pediatric abdominal pain related functional gastrointestinal disorders impose a large economic burden on patients' families and healthcare systems. More than one-half of total annual costs of IBS and FAP/FAPS consist of inpatient and outpatient healthcare use. TRIAL REGISTRATION: Netherlands Trial Registry: NTR2725. AD - Department of Pediatric Gastroenterology and Nutrition, Emma Children's Hospital AMC, Amsterdam, The Netherlands. Department of Pediatrics, St. Antonius Hospital, Nieuwegein, The Netherlands. Clinical Research Unit, Academic Medical Center, Amsterdam, The Netherlands. AN - 26329806 AU - Hoekman, D. R. AU - Rutten, J. M. AU - Vlieger, A. M. AU - Benninga, M. A. AU - Dijkgraaf, M. G. DA - Nov DO - 10.1016/j.jpeds.2015.07.058 DP - NLM ET - 2015/09/04 IS - 5 KW - Abdominal Pain/economics/etiology/*therapy Adolescent Child Delivery of Health Care/*economics *Disease Management Female Gastrointestinal Diseases/economics/etiology/*therapy Health Care Costs/*trends *Health Expenditures Humans Irritable Bowel Syndrome/complications/economics/*therapy Male Netherlands Surveys and Questionnaires LA - eng N1 - 1097-6833 Hoekman, Daniël R Rutten, Juliette M T M Vlieger, Arine M Benninga, Marc A Dijkgraaf, Marcel G W Journal Article Multicenter Study Randomized Controlled Trial Research Support, Non-U.S. Gov't United States J Pediatr. 2015 Nov;167(5):1103-8.e2. doi: 10.1016/j.jpeds.2015.07.058. Epub 2015 Aug 29. PY - 2015 SN - 0022-3476 SP - 1103-8.e2 ST - Annual Costs of Care for Pediatric Irritable Bowel Syndrome, Functional Abdominal Pain, and Functional Abdominal Pain Syndrome T2 - J Pediatr TI - Annual Costs of Care for Pediatric Irritable Bowel Syndrome, Functional Abdominal Pain, and Functional Abdominal Pain Syndrome VL - 167 ID - 3859 ER - TY - JOUR AB - Chronic pain syndromes in children and adolescents are defined as continuous or recurrent pain without an underlying causative diagnosis and lasting for more than 3 months. It is estimated that every fourth child in Germany suffers from chronic pain with every twentieth suffering from extreme recurrent pain. The incidence of chronic pain in children and adolescents is increasing with headache, abdominal pain and musculoskeletal pain being the most frequent. The quality of life declines not only due to the pain but to relieving postural and psychological factors, such as fear and sadness. School attendance, social activities and hobbies are mostly affected. This review summarizes the background of chronic pain syndromes and introduces a multimodal therapeutic approach. AN - WOS:000373646700011 AU - Hofel, L. AU - Draheim, N. AU - Hafner, R. AU - Haas, J. P. DA - Apr DO - 10.1007/s00393-016-0061-y IS - 3 N1 - Hoefel, L. Draheim, N. Haefner, R. Haas, J. P. 1435-1250 PY - 2016 SN - 0340-1855 SP - 292-301 ST - Pain syndrome of the musculoskeletal system in children and adolescents T2 - Zeitschrift Fur Rheumatologie TI - Pain syndrome of the musculoskeletal system in children and adolescents UR - ://WOS:000373646700011 VL - 75 ID - 2172 ER - TY - JOUR AB - Background Rheumatic diseases, such as juvenile idiopathic arthritis (JIA), are typically associated with acute pain mainly caused by inflammation. Chronic pain is described as pain lasting at least 3 months. In JIA patients chronic pain may occur despite successful treatment. Chronic pain and pain disorders frequently occur during the course of the disease despite successful control of inflammation. Objective Possible interrelations between JIA and pain disorders are presented. Method Besides a review of the available literature, a retrospective cohort study was conducted, including 906 patients with a chronic pain disorder with somatic and psychological factors (CPD) and/or a complex regional pain syndrome type I (CRPS I). The frequency of pre-existing rheumatic illnesses was analyzed. Results The JIA is a risk factor for the development of a CPD. Especially polyarticular, extended oligoarticular, enthesitis-associated JIA and psoriatic arthropathy were found to be significantly associated with an increased risk for developing CPD. In contrast, an increased risk for development of CRPS I was not observed. Conclusion Our study demonstrates JIA to be a risk factor for the development of chronic pain not only as a result from malpositioning or arthrosis but also as a chronic pain disorder (CPD). Further studies are necessary to clarify the relevance of disease activity and duration and also of psychological factors for the pathogenesis. AN - WOS:000606167900001 AU - Hofel, L. AU - Draheim, N. AU - Schramm, A. AU - Georgi, M. AU - Haas, J. P. DA - Apr DO - 10.1007/s00393-020-00956-3 IS - 3 N1 - Hoefel, L. Draheim, N. Schramm, A. Georgi, M. Haas, J. P. 1435-1250 Si PY - 2021 SN - 0340-1855 SP - 234-242 ST - Rheumatic pain and chronic pain in children, adolescents and young adults T2 - Zeitschrift Fur Rheumatologie TI - Rheumatic pain and chronic pain in children, adolescents and young adults UR - ://WOS:000606167900001 VL - 80 ID - 1765 ER - TY - JOUR AB - Background: Abdominal pain in childhood is common yet frustrating when unexplained. Objective: To describe the clinical features and outcome of 8 children (6 girls and 2 boys; mean[+/-SD] age, 13 +/- 2 years) with unexplained abdominal pain who underwent exploratory laparoscopy. Setting: All 8 patients were examined at an academic pediatric gastroenterology center and referred for exploratory laparoscopy because of unexplained abdominal pain. Laparoscopy was offered after family agreement to pursue behavioral management if the pain and disability did not improve. Results: In all 8 children, laparoscopy detected an anomaly at a site corresponding to that of the abdominal pain. Findings were adhesions in 7 children (3 colonic, 2 ileocecal, 1 gastric, and 1 appendiceal) and ovarian torsion in 1 child. At a mean follow-up of 12.6 months, the abdominal pain had completely resolved in 6 children, notably improved in 1 child, and continued unchanged in 1 child. Disability completely resolved in 2 of 3 children. Conclusions: In children with unexplained abdominal pain that is acute in onset, well described, and suggestive of peritoneal involvement, exploratory laparoscopy (1) successfully ends the cycle of abdominal pain in most cases; and (2) commonly identifies abnormalities, usually adhesions. However, whether laparoscopy, the placebo effect, or both promote the healing process is unclear. Further study is needed to develop criteria for referral for laparoscopic evaluation of unexplained abdominal pain. AN - WOS:A1997YA94600006 AU - Hoffenberg, E. J. AU - Rothenberg, S. S. AU - Bensard, D. AU - Sondheimer, J. M. AU - Sokol, R. J. DA - Oct DO - 10.1001/archpedi.1997.02170470027006 IS - 10 N1 - Hoffenberg, EJ Rothenberg, SS Bensard, D Sondheimer, JM Sokol, RJ Annual Meeting of the North-American-Society-for-Pediatric-Gastroenterology-and-Nutrition Oct 04, 1996 Denver, co N Amer Soc Pediat Gastroenter & Nutr Hoffenberg, Edward/0000-0001-5179-489X PY - 1997 SN - 1072-4710 SP - 993-998 ST - Outcome after exploratory laparoscopy for unexplained abdominal pain in childhood T2 - Archives of Pediatrics & Adolescent Medicine TI - Outcome after exploratory laparoscopy for unexplained abdominal pain in childhood UR - ://WOS:A1997YA94600006 VL - 151 ID - 2902 ER - TY - JOUR AB - Previously, it was shown that school-aged (9-14 yr) preterm and fullterm children with neonatal pain exposure exhibit elevated heat pain thresholds and heightened perceptual sensitization to tonic painful heat when tested under standard conditions [Hermann C, Hohmeister J, Demirakca S, Zohsel K, Flor H. Long-term alteration of pain sensitivity in school-aged children with early pain experiences. Pain 2006;125:278-85]. Here, changes in the psychosocial context of pain responses in these children, who had been hospitalized >or=7 days after birth including >or=3 days of treatment in a neonatal intensive care unit (NICU), are reported. Nineteen preterm (or=37 weeks gestational age) with NICU experience, recruited retrospectively and selected based on strict exclusion criteria, and 20 fullterm control children participated. Preterm NICU children endorsed more pain catastrophizing as compared to controls. Mothers of preterm children, who had been more severely ill and had been hospitalized longer than fullterm NICU children, were more likely to engage in solicitous pain-related behavior. Maternal influence was also assessed by comparing heat pain thresholds and perceptual sensitization to tonic painful heat obtained in the presence versus absence (i.e. standard testing conditions) of the mother. In all three groups, maternal presence was associated with increased heat pain thresholds. Control children habituated significantly more to tonic heat when their mother was present. The NICU children showed overall significantly less habituation than the controls; there was no modulating effect of maternal presence. Especially in highly vulnerable children such as preterms, neonatal pain exposure and prolonged hospitalization may, aside from neuronal plasticity, promote maladaptive pain-related cognitions and foster parental behavior that reinforces the child's pain response. AU - Hohmeister, Johanna AU - Demirakça, Süha AU - Zohsel, Katrin AU - Flor, Herta AU - Hermann, Christiane DA - 2009/01// DO - 10.1016/j.ejpain.2008.03.004 DP - PubMed IS - 1 J2 - Eur J Pain KW - Adolescent Adult Child Cognition Female Gestational Age Hot Temperature Humans Infant, Newborn Infant, Premature Intensive Care Units, Neonatal Male Maternal Behavior Middle Aged Pain Pain Measurement Pain Threshold Sex Characteristics Surveys and Questionnaires LA - eng PY - 2009 SN - 1532-2149 SP - 94-101 ST - Responses to pain in school-aged children with experience in a neonatal intensive care unit T2 - European Journal of Pain (London, England) TI - Responses to pain in school-aged children with experience in a neonatal intensive care unit: cognitive aspects and maternal influences UR - http://www.ncbi.nlm.nih.gov/pubmed/18439861 VL - 13 ID - 113 ER - TY - JOUR AB - Due to maturation-related plasticity of the developing nociceptive system, neonatal nociceptive input, as induced by medical procedures in the neonatal intensive care unit (NICU), may cause long-term alterations in pain processing. Using functional magnetic resonance imaging, this study investigated the cerebral pain response in school-aged children and adolescents (11-16 yr) with experience in a NICU after preterm (or=37 weeks gestational age, N=9) as compared to fullterm control children without early hospitalization (N=9). NICU children had been recruited retrospectively among former patients of the Children's University Hospital Mannheim. All children had participated in our previous studies [46,49] entailing psychophysical measurements. In response to tonic (30s) heat stimuli of individually adjusted moderate pain intensity, which were of comparable temperature across groups, the preterm but not the fullterm NICU children exhibited significant activations in a number of brain regions (thalamus, anterior cingulate cortex, cerebellum, basal ganglia, and periaquaeductal gray) that were not significantly activated in controls. The preterms showed significantly higher activations than controls in primary somatosensory cortex, anterior cingulate cortex, and insula. This exaggerated brain response was pain-specific and was not observed during non-painful warmth stimulation. Preterms' continuous pain ratings revealed a tendency for increased sensitization within and a lack of habituation across trials. In highly vulnerable children such as preterms, neonatal nociceptive input may, aside from other neurodevelopmental consequences, persistently increase the gain within pain pathways. AU - Hohmeister, Johanna AU - Kroll, Alexander AU - Wollgarten-Hadamek, Iris AU - Zohsel, Katrin AU - Demirakça, Süha AU - Flor, Herta AU - Hermann, Christiane DA - 2010/08// DO - 10.1016/j.pain.2010.04.004 DP - PubMed IS - 2 J2 - Pain KW - Adolescent Analysis of Variance Brain Mapping Cerebral Cortex Child Female Hot Temperature Humans Image Processing, Computer-Assisted Infant, Newborn Infant, Premature Intensive Care Units, Neonatal Magnetic Resonance Imaging Male Pain Pain Measurement Pain Threshold LA - eng PY - 2010 SN - 1872-6623 SP - 257-267 ST - Cerebral processing of pain in school-aged children with neonatal nociceptive input T2 - Pain TI - Cerebral processing of pain in school-aged children with neonatal nociceptive input: an exploratory fMRI study UR - http://www.ncbi.nlm.nih.gov/pubmed/20471751 VL - 150 ID - 108 ER - TY - JOUR AB - BACKGROUND: Pain problems are a rapidly growing health problem found among both children and adolescent, and about 15-30% have reported chronic pain problems. School nurses in Norway meet adolescents with various ailments, including pain. Yet research on how school nurses perceive the pain experienced by adolescents is limited. The aim of the present study was to explore how school nurses explain and experience the everyday pain of adolescents. METHOD: A qualitative study with an explorative design comprising five focus group interviews. Each group consisted of three to five school nurses. Seventeen female school nurses in five junior high schools in Norway, age range 29-65 years participated. To cover the issues a semi structured interview guide was used. The transcribed text was analysed with qualitative content analysis. RESULTS: The experience of school nurses with adolescents' pain in everyday life is mainly that pain is a social, physical, and psychological phenomenon. School nurses experienced that everyday pain is reflecting: 1) high expectations, 2) difficult relationships and traumatic experiences and 3) an unhealthy lifestyle. School nurses have ambivalent attitudes to medicalisation of pain. CONCLUSION: Despite of a biopsychosocial understanding of pain, the school nurses maintained referral practice of medical examinations, with the results that many adolescents became shuttlecocks in the health system. Although the school nurses´ were sceptical of the tendency towards medicalization in society, it appears that they actually help maintain this tendency. AU - Høie, Magnhild AU - Haraldstad, Kristin AU - Rohde, Gudrun AU - Fegran, Liv AU - Westergren, Thomas AU - Helseth, Sølvi AU - Slettebø, Åshild AU - Johannessen, Berit DA - 2017 DO - 10.1186/s12912-017-0247-x DP - PubMed J2 - BMC Nurs KW - Adolescents Biopsychosocial understanding Pain School nurses LA - eng PY - 2017 SN - 1472-6955 SP - 53 ST - How school nurses experience and understand everyday pain among adolescents T2 - BMC nursing TI - How school nurses experience and understand everyday pain among adolescents UR - http://www.ncbi.nlm.nih.gov/pubmed/28924390 VL - 16 ID - 72 ER - TY - JOUR AB - Biomedically, the mouth is often described as a "window on the body"; many systemic health issues may manifest in the oral cavity. The metaphor of a "window" also holds true for the sociological impact of the mouth; judgements and assumptions about social status and affluence may often be made based on dental appearance. The mouth may be used by society to determine the value a person is perceived to place on self-care. Those who are afflicted with dental disease, and therefore have poor dental appearance, are often assumed to be neglectful. Given the importance that is placed upon the appearance of the mouth, it is no surprise that cosmetic dentistry has developed as a service offered by the profession, with novel treatments becoming popular as a way of changing dental appearance. The development of cosmetic medicine has enjoyed wide discussion within the sociological literature. Whilst dentistry has undeniably evolved from medicine, and therefore shares many parallels concerning ethical and social considerations, dentistry differs fundamentally in its organisation, the nature of the conditions most commonly managed and the expectations of patients seeking care. This article investigates the socioethical issues specifically raised by cosmetic dentistry. The dental profession's scope as the protectors and restorers of the oral cavity from the effects of dental disease has now expanded to include the treatment of the flawed smile. Some within the dental profession advocate for commentary on dental appearance to be made to patients as routine practice, accompanied by associated recommendations for possible treatments to rectify perceived deficiencies. The place of cosmetic dentistry as a legitimate professional pursuit has not been explored widely. Comprehensive explorations come from Welie, who analyses both the professional and moral status of cosmetic intervention within the sphere of medicine and dentistry, and from Ozar and Sokol, who consider the place of aesthetic values in relation to other central values in the profession. This article examines closely how cosmetic dentistry is classified and the consequences of this upon the position of cosmetic dentistry as discipline. The inclusion of dentistry in the discussion of the position of cosmetic procedures within medicine is fraught. Whilst the origins of dentistry are from medicine, the nature of dentistry has become somewhat different from its progenitor; the consequences of this in relation to the classification of cosmetic dentistry cannot be overlooked. Within this study of cosmetic dentistry, the reader will note the use of both "patient" and "consumer" as terms to describe those who may seek the services of healthcare professionals. It is noticeable within modern society that many who would have once considered themselves to be patients, now place themselves in the role of consumers, and would describe themselves as such. To place an immediate value upon this as a negative sign of the increased influence of commercial pressures within healthcare would be unreasonable. To be described as a consumer, confers the assumption of a set of rights relating to how one must be treated. Consumers are powerful; emphasis is placed upon their ability to "vote with their feet" and thusly control the quality of service that they receive. Increased choice and freedom to exercise this are also hallmarks of the modern consumer of health services. Whilst contemporary discourses upon the role and status of the patient state largely the same, the descriptor would seem only to be held dear to the health professions and those who study them. There is also a potential negative aspect to the introduction of the healthcare consumer; one where the overarching professional duties to do no harm and to engage in the exercise of informed consent seem less important. Here, respecting the ultimate authority of the health consumer to dictate the service that they would like to receive is viewed by many professionals to be equivalent to patient primacy. Where those who seek care are described in this study as being consumers, it is a reference to the status of those seeking treatment as being empowered, and equal to those who provide treatment. It is also an acknowledgement of the rights of care-seekers to be treated as ends in themselves, rather than as means to ends. Where the negative aspects of consumerism in healthcare are encountered, these will be explicitly addressed. This article will have three main areas of discussion. Firstly, the common assertion that cosmetic dentistry is separate from the rest of dentistry, as is often claimed of cosmetic surgery and medicine, will be explored and challenged. In doing this, Foucault's concept of "care of the self" will be used to understand a possible framework where cosmetic dentistry may become a legitimate part of healthcare; the pursuit of self-improvement being an integral aspect of well-being. Secondly, the relationship between cosmetic dentistry and commercialisation of healthcare will be examined. How cosmetic dentistry may be portrayed and "sold" to patients, and the tensions that this may lead to in relation to notions of professionalism. This is an important branch in the narrative surrounding cosmetic dentistry but raises questions that are relevant to professional ethics rather than definitions of cosmetic improvement in the oral cavity. Lastly, another concept described by Foucault will be applied to cosmetic dentistry. The idea of the "dental gaze" suggests that the cosmetic enhancements offered by the dental profession offer a socially mediated control on the concept of the ideal smile. The way that this is often enforced through professional discipline will be explored and critiqued. This study will examine the extent to which criticisms of the professional status of cosmetic dentistry still apply to contempory practice. Foucault outlined his theory of care of the self in the second and third volumes of the History of Sexuality. This idea of ethics examined practices that an individual might engage in, so as to transform their own mode of being. An important aspect of this ethics is the challenge to the established pursuit of the "hermeneutics of the subject," with Foucault placing emphasis upon the care of the self, rather than self-knowledge. Foucault analysed Ancient Greek and Roman texts, developing ideas of how individuals might form themselves as ethical subjects, enabling transformation. The Ancient Greeks took this as how one might live well, whilst under the Romans, this evolved to be concerned with developing the "good-self." He stated the practices facilitating this development to be; "the procedures, which no doubt exist in every civilisation, offered or prescribed to individuals in order to determine their identity, maintain it, transform it in terms of a certain number of ends. " Care of the self is characterised by a continual process of self-improvement that may be achieved by many processes, including; self-reflection, self-examination, self-decipherment and self-transformation. Foucault does not pose care of the self to be an obligative duty; it is instead positioned as an ethics that encourages active freedom to engage in processes of cultivation of the self. The concept of care of the self would appear to have implications for cosmetic treatments as acts within the process of self-cultivation. Cosmetic enhancement could be positioned to be an act of self-improvement in line with care of the self; Foucault termed them to be, "technologies of the self." If through introspection, an individual becomes aware of a perceived deficit in their appearance that negatively impacts upon their confidence and self-esteem, having this addressed through cosmetic intervention would be a positive ethical act. Through the ethics of care of the self, we see the normalisation of cosmetic treatment and the removal of the stigma of vanity, and the concept of self-improvement being incorporated within the wider definition of health. Through this, cosmetic intervention may be seen as; "a primary mode for articulating the authentic, healthy and happy self." Cosmetic interventions provided by healthcare practitioners cause definitional difficulty. It is traditionally a point of dispute as to whether cosmetic surgery forms a legitimate aspect of healthcare practice. Proponents of medical professionalism have suggested that the social contract existent between the health professions and society places the purpose of medicine to be the treatment of disease and alleviation of suffering. Cosmetic interventions are specifically excluded from this concept of medical purpose, due to their nature as non-therapeutic procedures within strict definitions of health. Because of this lack of legitimacy in line with the given parameters of medicine, historically, cosmetic surgery has been considered by early physicians; "to be minor, without healing purpose, and relegated to lay-practitioners." Many surgeons would also refuse to perform cosmetic surgery, terming it "beauty surgery." More difficult than addressing whether cosmetic surgery is a legitimate part of medicine, is addressing the question of how cosmetic dentistry integrates with the rest of the pursuits of the dental profession. Oral Health is defined by the WHO to be; "essential to general health and quality of life. It is a state of being free from mouth and facial pain, oral and throat cancer, oral infection and sores, periodontal (gum) disease, tooth decay, tooth loss, and other diseases and disorders that limit an individual's capacity in biting, chewing, smiling, speaking, and psychosocial wellbeing." Whilst undoubtedly biomedical in focus, the definition does reference the capacity to smile and the effects of deficiencies in this ability upon psychosocial wellbeing to be firmly part of oral health. Concepts of this strong association between psycho-social and traditional biomedical factors, are made clearer by The World Dental Federation (FDI), who define oral health as; "multi-faceted and includes the ability to speak, smile, smell, taste, touch, chew, swallow and convey a range of emotions through facial expressions with confidence and without pain, discomfort and disease of the craniofacial complex. " This definition again references smiling and includes the concept that being able to do so with confidence to be an integral part of oral health. Ozar and Sokol recognise the importance of aesthetic values within dental practice. They acknowledge that dental professionals who paid no attention to aesthetic values would be failing professionally, both from the perspectives of their professional peers, and from the public utilising their services. Because of this, they place aesthetics as a core tenent of the profession's values. Despite this recognition, within their ranking of core values, aesthetics is separated from consideration as part of oral health, which is placed as a higher value than aesthetics. Some have advocated that, as with medicine, a strict demarcation exists in the professional status between dentistry carried out for therapeutic reasons and that which is carried out for cosmetic purposes. Welie states that; "ugliness is not a medical indication; it does not necessitate medical treatment in the same way that a toothache, gingivitis or oral cancer does." He also states that the professional status of dentistry is lost when dentists focus their practices upon the provision of purely aesthetic interventions. The issue of what constitutes a cosmetic or a medical issue is dealt with by Welie by distinguishing between conditions which are healing and those that are enhancing. He uses two examples of similar conditions which both affect dental appearance; firstly, that of cleft-lip and palate, and secondly, the crowding and misalignment of teeth in malocclusion. Welie suggests the term "integrity" as a synonym for health. He questions whether the aesthetic considerations of repairing a cleft-lip and palate is any more medically justified than that orthodontic treatment. He states that integrity is not violated by having an ugly appearance and that whilst aesthetic considerations and side-effects are important; they are not within the realms of medical consideration. Therefore, aside from fixing any functional deformity, both procedures fail to count as being medical procedures if carried out solely on the basis of dental appearance. Welie places culture as the main determination as to why perceived defects in dental appearance are considered to violate integrity; it is social environment that determines attractiveness. He questions whether the improvement of a person's appearance restores integrity, thus making it a bona fide medical intervention, or whether it is an enhancement because ugliness is not a contraindication to integrity. It is of note that Welie does not recognise any differences between the fundamental purposes of medical and dental practice; classing both to have equal foundations within the tradition of treating pathology and pain only. The heavy burden of justification upon cosmetic dentistry is derived from its subjective nature. Orthodontics in not questioned in the same way, despite relying upon the same subjective reasoning for providing treatment. Certainly, by the categorisations of Welie, orthodontics is undoubtedly non-medical in nature, unless aesthetics is not the primary reason for treatment. The intrinsic difference that would seem to exist in other areas of cosmetics and general health is the idea that in cosmetic interventions, the objective is to make the patient more, or better than, well rather than to restore health. Again, in dentistry this point of differentiation struggles to find legitimacy, especially so if the ethics of self-care are considered. Rose stated; "The old lines between treatment, correction, and enhancement can no longer be sustained." The apparent lack of distinction between general dentists and "cosmetic dentists" is also testament to the close alignment between cosmetic dentistry and professional activities that treat oral disease. The Health Care Complaints Commission in NSW, Australia stated that; "A central characteristic of cosmetic surgery is that it is initiated by the consumer to improve their appearance and self-esteem." Cosmetic dentistry (and the whole cosmetic discipline) is patient driven, which places cosmetic dentistry in line with ideals of bioethics and consumer culture, where those seeking treatment are empowered. If the traditional purpose of dentistry is expanded to accept the practice of cosmetic dentistry, this new goal of beauty as a good available to consumers, aligns with the reduction of power and authority held by clinicians and with the desire to enhance patient autonomy. Exley suggests that cosmetic dentistry may continue to develop as a normalised aspect of self-care, in the same manner as toothbrushing has become an integral part of most home-healthcare regimes. In this comparison, Exley quotes Davis, who suggests that the rise in the use of toothpastes was, "a social trend greatly aided by the efforts of commercial interests." The social demand to have an aesthetically pleasing smile has also driven the popularity of tooth-brushing. The introduction of active whitening ingredients into many toothpastes, reinforces Exley's comparison and suggests that the social acceptability of dental cosmetic enhancement is likely to sustain its growth in popularity, becoming accepted as part of everyday routine. The triptych of absence that determines the nature of a procedure to be cosmetic is; firstly, the absence of a patient, instead a consumer seeks and initiates treatment; secondly, the absence of pathology and; thirdly, the absence of a therapeutic purpose. Originally, cosmetic surgery was justified through being claimed to act as a psychiatric intervention. As improvements to confidence and self-esteem began to be seen by society as legitimate justifications to cosmetic intervention, much virtue is derived from the desire of the public to seek such treatment. The desire to create improvement of appearance and development of both self-esteem and confidence are ubiquitous within all dental treatments. Given this universality, as well as the empowerment of all patients as health consumers, it is difficult to really distinguish between many cosmetic and traditionally therapeutic treatments in dentistry. Further evidence towards the concept of there being little difference between cosmetic, and the rest of dentistry, is the existence of the idea of aesthetic failure which is a routine consideration in dental practice. Aesthetic failure occurs when a restoration remains structurally and functionally sound but loses its aesthetic properties. This, for many (including those who may think dimly of cosmetic treatments), is justification enough for removal and replacement. Aesthetics is a primary consideration for the majority of dental procedures, often being the only consideration for many patients. This in a stark contrast to medicine, where aesthetics often becomes a secondary consideration; for example, an unsightly scar is perhaps a small price to pay for a successful, life-sustaining surgery. References to the mental health of those seeking cosmetic treatments are made by the Medical Board of Australia and General Medical Council (UK) in their regulatory guidance. Medical practitioners providing cosmetic treatments are obliged to consider the need for independent psychological assessment. There is no equivalent guidance from the Dental Board of Australia or the General Dental Council (UK). This absence may indicate a more relaxed attitude within society towards dental enhancement, that to require practitioners to refer when concurrent psychological morbidity presents would be unrealistic and ultimately irrelevant in the majority of cases. However, a more relaxed position does not mean there is any less requirement for awareness of patients seeking cosmetic dentistry who may be suffering with body dysmorphic disorder. Treatment of these individuals with cosmetic dentistry, without addressing any underlying psychological pathology, would not contribute to the increasing of well-being and human flourishing. Therefore, the essential element that the ethics of care of the self would require to qualify an intervention as ethical is missing, rendering the treatment unjustifiable through this theoretical framework. In summary, cosmetic dentistry would seem to be included within the definition of professional dentistry. To exclude it on the belief that improvements in self-esteem and confidence are trivial and non-bona fide justifications deny the widened definition of oral health given by both the WHO and the FDI. It would also serve to excise a large portion of the dental profession, the main role of which is to provide treatments which primarily improve dental appearance. The dental professional goals of yesteryear may have been firmly fixed upon alleviation of suffering. However, in the 21st Century it seems somehow denialist to suggest that the improvement of confidence and self-esteem is not part of the professional purpose of the dental profession. Data pertaining to cosmetic dentistry is scant, the American Academy of Cosmetic Dentistry (AACD) reported that 86% of patients seen by their surveyed members reported that their main reason for seeking cosmetic dental treatment was an improvement in self-esteem. It is of note that the next greatest reason (at 51%) was the correction of previously failed cosmetic treatment. The Academy does not elaborate upon what is defined to be a failure; this could be structural failure or aesthetic failure, where the cosmetic expectations of patients are not met, either immediately or sometime after the procedure. It is difficult to reconcile ideas of cosmetic treatment as an ethical methodology of care of the self, with the image on the front cover of the AACD report. The picture is of a mouth being examined with a common dental mirror. In the mirror, it isn't the patient (or consumer) who is reflected; but the face of George Washington, taken from the US one-dollar bill. It is this overt reference to the financial reward of cosmetic dentistry, that leads to concerns about the relationship between cosmetic dentistry, ethics and professional culture. The semiotics of this image would suggest that it is not the needs of the patient that are reflected in the practice of cosmetic dentistry. Instead, the image suggests it is profit and personal reward that is the driving-force in providing these services. Cosmetic dentistry and surgery is often justified by reference to consumer culture and psychological well-being. The narrative of consumer rights and psychological imperatives within cosmetic disciplines is dominant, with procedures being justified purely on the basis that patients have demanded them. Whilst respect for the patient as an autonomous being is the key-stone of any patient-clinician relationship, the idea of the truly equal clinical interaction is a myth. There is commonly a disparity in knowledge between patient and clinician regarding dental treatment. There is a problem with valid consent if it is not used to promote the freedom of a patient through attempts to reduce this informational inequality. For example, we may fully accept a patient's right to seek a cosmetic dental treatment, however, many of these are highly destructive and are likely to carry with them serious repercussions for future oral health and treatment need. For a patient to make a truly free choice, they need to be made aware of this. This is where the "new" paradigm of the patient as a consumer struggles; the professional nature of dentistry requires for the patient to be told of this risk and possible alternatives. The provision of treatment as a commercial good on the presumption that the patient pays their money and takes their choice (or chance), pushes dentistry away from its professional obligation of effacement of self-interest and patient primacy. This tension reveals the issues of viewing cosmetic dentistry to be a consumer-product rather than a bona fide therapeutic intervention, carried out as a full part of the professional purpose. When taken as a consumer product, the emphasis of treatment becomes one of an indulgence; a consumer luxury where the consumer expects their rights of autonomy to be absolute. Here we see the evolution of the dental surgery into the "dental spa," with the world of the beauty industry and clinician colliding. This paradigm leaves little room for the therapeutic alliance; where the skill of the clinician is utilised within a framework of professional (rather than consumer) duty and expectation. The view of the patient as an empowered consumer is to be encouraged, but only in so far as the professional status and associated obligations that accompany this are preserved. The spa-model of dental practice finds procedures to be marketed as "pamper products." Botox, lip-fillers and teeth whitening have seen a surge in popularity within the dental armamentarium. This is despite many regulators of the dental professions worldwide stating almost universally that cosmetic injectables have limited place in the practice of dentistry. The rise in the portrayal of cosmetic dentistry as being a luxurious and pleasurable experience links with the concept that self-improvement through enhancement is fun and exciting. Dental tourism, like its counterpart in the medical industry, is perhaps the ultimate demonstration of this combination between pleasure and cosmetic enhancement. Within medicine, clinicians often argue that "medical spas" are in fact clinics, with preference for the use of medicalised terminology to describe the premises and procedures. This is in contrast to many dental surgeries that focus upon cosmetic treatments in preference to other forms of traditional dentistry, where practitioners seek to distance themselves from the perceived discomfort of conventional dental procedures. The initiation of many treatments within dental practice is patient-driven, but the treatments are not necessarily cosmetic in nature. The rise of insurance to cover the costs of oral health needs has contributed to dentistry be more consumer-focused. Patients may attend for a professional clean, with little therapeutic need, in part because they feel it is owed to them for having paid for insurance. This is a phenomenon that has no equivalent in medicine; those with private medical insurance would be unlikely to seek a medical consultation and treatment, simply because they felt that they had paid for it through insurance. The focus upon getting patients into the chair has led to many dentists offering free consultations. Bishop quotes Dr Harlan Pollock, a plastic surgeon, who is critical of such offers, stating; "Free consultations are a gimmick that are used in obtaining patients and they're worth about what they cost horizontal ellipsis They are an opportunity to sell an operation and serve very little purpose." Many cosmetic treatments, such as veneers, teeth whitening and facial injectables, are both the instruments for obtaining a desired effect, and the effect in themselves. The unnatural, bright, white and perfectly aligned smile or swollen and puckered lips are overt status symbols in their own rights and sought after by many for that reason. Franks gives three parameters to consumerism; 1) the pleasure of spending money and conspicuous consumerism; 2) relentlessness and transience, whereby enough is never enough and; 3) the individualisation of the bases and morality of action. In the context of cosmetic dentistry, this may lead to consumers seeking whiter, brighter and more accentuated dental appearances. Leiss articulates this as the practice where; "(T)he needs of self-esteem and self-actualization are expressed and pursued through the purchase of commodities." The push for ever brighter teeth can be seen within the instruments of the dentist. At one time, the "A1" shade was the brightest that was achievable; composite filling materials, porcelain shades and artificial teeth for dentures were made to conform to this scale. This is no longer the case; the popularity of procedures such as tooth whitening have led to the development of brighter shades. Dentists report that for many, the old maximum of A1 has become inadequate. The perceived neo-liberal entitlement to spend resources as an individual deems fit, is an element which society is oriented to defend and preserve. Where cosmetic dentistry is particularly challenging is where patients develop unrealistic expectations, through advertising or direct clinician salesmanship. Where this happens, the development of perceived needs which do not exist, or real needs that are addressed with irrelevant objects, may lead patients to have treatment that is inappropriate. This is where dental practitioners have a need to be robust in the way that they discuss treatments and expectations with patients. Advertising, whilst having the potential to be manipulative, cannot be said to always create false needs. It is easy in this circumstance to use this criticism of consumerism to negate the possibility of cosmetic dentistry being provided justifiably. Leiss states that needs and objects define one another, that ultimately, both real and manipulated needs are underpinned by individual values. The judgement of clinicians, who might feel that the perceived cosmetic defect does not warrant the intervention, asserts one aesthetic ideal over another. The act of refusing to provide treatment on this basis, rather than on a basis of judgement on clinical appropriateness, valorises the clinician's view of what is aesthetic. Patients are told that treatment is not possible on the basis that it does not strictly adhere to the normative view of what should be treated. This needs to be accepted as a socially mediated response, that imposes the beliefs of the clinician, onto the patient and judges them based on that schema. Commercialised models of dentistry encourage dental skill to be thought of as a commodity, owned by dental practitioners, available only to those who might be able to pay. As discussed, this contributes to the perception of dentistry to be a luxury good. This applies to all circumstances where dentistry is commodified, not only in consideration of cosmetic practice. In this circumstance, the cost, availability and quality of treatment are determined by open competition between providers, where the self-interest of practice owners and clinicians will bring price and quality into an acceptable balance. In this paradigm, the bioethical principle of justice is replaced by a market-driven model whereby patients may access only that for which they can pay. Welie uses the principle of justice to argue between the separation of medical care and non-medical care. He states that it would be unjust for a society not to offer equal access to dental hygiene, but that it would not be considered unjust for society to have unequal access to an intervention such as laser-eye surgery. This is a valid argument in so far as the wearing of eyeglasses is not a point of stigma within society; considering the popularity of non-prescription eyewear, this is reasonably obvious. However, Welie does not compare like with like. It can be reasonably well established that dental appearance has significant influence over how an individual is perceived in society. Moeller et al. noted a considerably higher public awareness of an association between social deprivation and poor oral health in comparison to other health conditions such as cancer, diabetes and depression. This is believed to lead to greater possibility of association between dental appearance and assumptions being made about socioeconomic status, with the potential for discrimination on this basis. Bedos et al. found that those receiving social assistance, who are disproportionately afflicted with poor oral health and associated poor dental aesthetics, place great value upon the appearance of their teeth. The participants complained about decline in dental appearance and the associated, negative impacts this had upon their self-esteem, social interactions and whether they could secure gainful employment. Reports of hopelessness relating to this situation lead to a preference in extractions and opting for complete dentures. This is supported by Khalid and Quinonez, who state that those without conformity to the expectation of dental appearance celebrated and enjoyed by the social elite, are assigned negative personality and character traits. Whilst Welie might be justified in describing a lack of outrage relating to unequal access to non-medical interventions, the concept of "cosmetic justice" in relation to dentistry holds merit given the huge impacts that effect those who suffer a decline in dental aesthetics. Despite this, the NHS in the United Kingdom states that; "NHS dental treatment does not include cosmetic treatments that are not clinically necessary horizontal ellipsis Cosmetic treatments horizontal ellipsis are used to improve the appearance of your teeth and make them look more attractive, and are only available privately." Whilst the boundaries of a public health system need to be realistic, an artificial demarcation between cosmetic and therapeutic treatments assumes that the differentiation between these two categories within dentistry is obvious, if it exists at all. To remain with the example of the NHS, cosmetic operations such as the provision of breast implants have been carried out on the justification of improving mental wellbeing and human flourishing. In would seem incongruous for cosmetic dental treatment to be treated differently. The reality of the situation is that often the demarcation between cosmetic and traditional treatment becomes indistinguishable; providing a patient with a set of dentures to enable them to chew or provision of a crown to aid structural integrity may also have the simultaneous effect of enhancing appearance. One imagines that few dental professionals would argue that the cosmetic improvement was merely a by-product of restoring function. This again shows that the separation of oral health and aesthetics is indeed artificial and that the two concepts are frequently intertwined to the point of being inseparable. In this way, where public dental services are provided, whilst policy directions may state that cosmetic treatment is not available, this is not a position that is practically enforceable; only purely cosmetic procedures are able to be realistically excluded. Whilst cosmetic dentistry is not in itself damaging to professional ethics and professionalism, if undertaken in a manner that is consumer-driven, converted into a commodity, it has the potential, as well as the rest of dentistry and medicine, to radically change the dynamics of the social contract. Commercial strategies such as advertising typically walk a fine line between scaring patients, through directing attention towards possible deficits, and offering pleasure or satisfaction. Advertising has the potential to damage patient autonomy when used in a manner that is manipulative and this practice should be universally regulated and condemned. Dental appearance is a fundamental factor in how individuals are perceived and judged by society. The dismissal of cosmetic dentistry as part of the legitimate practice of dentistry is illogical; the separation should instead be between cosmetic dentistry and commercialism. The tradition of surveillance in dentistry is long established. Nettleton describes the dentist as a "tooth-judge," stating; "The duty of the dentist was not just to invade the mouth but to monitor and regulate and thus to contribute to the policing of bodies." The preventative focus of dentistry is testament to the profession's role in observing and measuring the mouth. Nettleton's description of the dentist-as-judge places the dental professional in a position to exercise disciplinary power. Foucaldian accounts of power allow description of three instruments through which a dental professional may exercise disciplinary power; firstly, through hierarchical observation; secondly by utilising normalising judgement; and thirdly, combining the first two instruments in the process of the clinical examination. Through the process of hierarchical observation, subjects are placed into a state of perceived continuous surveillance, regardless of whether this surveillance is continuously in operation. Normalising judgement involves the evaluation and comparison of individual patients to established norms. This allows the dentist to declare patients to be either "normal" or "abnormal" and conformity assured through correction. The examination is the result of the combination of hierarchical observation and normalising judgement. This instrument permits, "the subjection of those who are perceived as objects and the objectification of those who are subjected horizontal ellipsis in this slender technique are to be found a whole domain of knowledge, a whole type of power." Through the dental examination, each mouth could be scrutinised and if deviation from the norm detected, this can be corrected. The power of the dentist has traditionally been used to assert conformity to norms of absence of disease, for example, through the filling of carious teeth, or in the instruction of the proper manner to maintain a plaque free mouth. In the modern era, dentists have expanded their powers of disciplinary observation and the normalising gaze, through social networking sites such as Facebook and Twitter. Advertising pages for dental practices on social media frequently use advertising to remind patients to maintain proper oral hygiene and attend regularly. This also extends to how teeth are depicted, and cosmetic procedures represented. The ideals and beliefs of the dental profession of the ideal mouth may be enforced through the normalising gaze, whereby patients may be subjected to the professionally-held norm of a well-aligned, white smile, in a mouth with lips of ideal proportion. The dental professional does not have to explicitly subject the patient to this norm; the patient is bombarded with messages within the practice environment, through promotional and educational materials. It would be wrong, as Khalid and Quinonez note well, to suggest that the dental profession is solely responsible for the setting of societal norms relating to what constitutes the ideal smile. It would be more appropriate to describe the dental profession as being an enabling factor to society's desire for a mouth that looks a certain way. The profession's disciplinary authority and expertise of what can be achieved, drives the notion of what a disciplined smile may be. It is through schools of professional theory that dentists are trained to exercise their powers of hierarchical observation. The establishment of the dental profession in the early 20th Century led to the legitimisation of the dentist as an authority in enforcing the norms of the ideal smile that are ultimately informed by society. The power of the profession comes from the stigma of poor oral health; "They conform to norms not because they are afraid of the power itself, but because of the possibility of facing penalty, namely, negative stereotyping of individuals with 'bad' teeth." The practices of the dental profession in engaging in exploitative advertising, designed to induce perception of treatment need, and the complicity of professionals in consumption-focused practice (the relentlessness of consumerism) helps to enforced societal norms. Otto illustrates this well in telling the story of Mame Adjei, the winner of Miss Maryland in 2015. As part of her competition prize, she is awarded ten thousand dollars towards treatment at one of the award's sponsors; a cosmetic dentist. She tells of how Adjei sits in the dentist's waiting room, bombarded with images of other beauty pageant winners who have received treatment and professional messages such as; "Like they say with the lottery, you gotta be in it to win it. You have to play the game. Life is hard enough and a bright, beautiful smile can help open doors and hearts." Following her consultation, Adjei reports feeling more aware and critical of her teeth and decides to embark upon the treatment recommended to her. After this, Otto describes a person in conflict; Adjei has had the treatment she perceived she needed to progress in the pageant world but is also disturbed by the process; "I'm like an art project horizontal ellipsis I don't think I needed it horizontal ellipsis I don't mind my little special things about me. Now my teeth look like everyone else's." This is a stark example of the "gaze" being applied to ideal norms of aesthetic beauty. The "gaze" of the cosmetic dentist becomes manifest in the use of computerised or conventional technologies that show patients the predicted outcome of treatment. Programmes may alter patient's smiles digitally or through the "diagnostic" wax-model of teeth produced by the dentist to show what might be realised through cosmetic intervention. Here the dentist specifies the parameters of how they will transform the smile. These processes can be likened to the whorls and lines of the cosmetic marker pen in surgical consultations. The specialised training and professional status of dentists, places them in a position of authority. This authority, combined with the culturally derived notions of ideal dental aesthetics, makes it difficult for dental professionals to be neutral participants in changing the appearance of the mouth. The dental profession could be seen to have a vested interest in not challenging prevailing social norms; after all, cosmetic dentistry will always offer dentists an alternative stream of income regardless of any decreasing prevalence of dental disease. It could be argued that the dental profession has a duty to contribute to the destigmatisation of alternative appearances, addressing the paradigm where individuals with facial and other deformity are disabled by the culture around them rather than any physical or functional impairment. Twine notes that there is a tendency to scoff at how foolish society was in the days of yesteryear to place any weight upon the pseudo-science of physiognomy, and yet how prevalent these ideas within society still remain. Through a collective addressing of this issue in dentistry, the profession may have the potential to alter prevailing cultural attitudes towards the ideal dental appearance, especially as teeth are an essential part of the physiognomic assessment that is often made of an individual's character and morality. Comment should be made on the fluidity of cultural preferences in dental appearance. Blackened teeth, that elicit stigma and assumptions of low socio-economic status and self-neglect in Western culture today, would have led to opposite conclusions of affluence in the 16th and 17th centuries. The cost of sugar in these periods meant that tooth decay was an affliction of the rich. Likewise, tooth blackening (as opposed to teeth whitening) was once considered to be an enhancement of beauty, partly favoured as it disguised the sharpness of canines which were associated with animalistic or evil tendencies. Within Japanese culture, there is a preference, in some, for "yaeba"; a characteristic appearance where the canine teeth are prominent. It is believed that this prominence suggests a youthfulness and is considered to be attractive by many. Whilst many have their teeth aligned to conform to the Western preference of straight teeth, having orthodontics to pronounce canines is still relatively common. Across cultures, preferences in tooth appearance may contrast and the current preference for uniformity in alignment and enhanced brightness in Western culture may change in the future. In this discourse examining cosmetic dentistry, the problems of attempting to separate the practice of dental cosmetics, and treatments that may be categorised as treating dental disease and suffering, become evident. The insistence that cosmetic dentistry somehow sits outside of the professional purview of dentistry is untenable based upon both how oral health is defined, and the great value that society places on dental appearance. Instead, the distinction must be made between cosmetic dentistry and commercially-focused dentistry, where the practice and role of the dental professional changes to being one more similar to a facilitator of consumerist culture. Often, this is where tensions between cosmetic dentistry and notions of professionalism have arisen, the established and commonly-held belief being that commercialism and that aspect of dentistry are inextricably linked. Cosmetic dentistry has no moral value attached to it that makes it immediately objectionable to professional purpose. Where this becomes compromised is through the introduction of action of behalf of the profession that conflict with the effacement of self-interest, such as exploitative advertising, overtreatment or defacement of the dentist-patient relationship into one of commercial exchange. It can be concluded that cosmetic dentistry can deliver benefits to oral health and join the pantheon of professional dentistry, but only when the requirements of informed consent that preserve patient autonomy and resistance to commercial factors are observed. The ethics of care of the self and the concept of the dental gaze may be thought to be opposites of the same coin; patients should have the freedom to consume cosmetic dentistry in a manner which will develop personal growth and self-improvement. To refuse cosmetic dentistry as an ethical tool for this purpose would be to deny a bona fide instrument of self-cultivation. The converse in this relationship is the dominance and authority of the dental profession, with the dentist placed as the arbiter of the norms of dental appearance. Professional judgement is then developed into a sales-pitch to sell this normalised view of what dental appearance should be. In this, the dentist acts to validate and impose the socially determined parameters of what might be considered an ideal dental appearance. The findings of this study into the nature of cosmetic dentistry have implications for how treatment that is primarily aesthetic in nature may be judged by the profession, and by those that fund public dental services. 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Zumbroich, T. J. (2009). 'Teeth as black as a bumble bee's wings': The ethnobotany of teeth blackening in Southeast Asia. Ethnobotany Research & Applications, 7, 381-398. Introduction Definitions and Legitimacy: Self-Care Ethics and Concepts of Cosmesis in Dentistry Cosmetic Dentistry and Consumerism The Dental Gaze and Cosmetic Dentistry Conclusion Footnotes Cosmetic dentistry is a divisive discipline. Within discourses that raise questions of the purpose of the dental profession, cosmetic dentistry is frequently criticised on the basis of it being classified as a non-therapeutic intervention. This article re-evaluates this assertion through examination of ethics of care of the self, healthcare definitions and the social purpose of dentistry, finding the traditional position to be wanting in its conclusions. The slide of dentistry from a healthcare vocation towards being a predominantly business-focused interaction between clinician and consumer conflicts with traditional notions of dentistry as a profession. Whilst it is undeniable that cosmetic dental treatment particularly lends itself to the commercial paradigm, this is not exclusive to this area of professional practice. The cultural basis of dental appearance and the potential of the dental profession to exert coercive pressure upon the public to undergo treatment that is based upon social norms is discussed. This essay concludes that cosmetic dentistry is undeniably part of the professional purpose of 21st Century dentistry. However, the caveat that may be placed upon this, is that this status is conditional upon the professional conduct of dental practitioners remaining resilient to commercial practices not compatible with professional obligations. AN - WOS:000450332600009 AU - Holden, A. C. L. DA - Nov DO - 10.1111/bioe.12498 IS - 9 N1 - Holden, Alexander C. L. Holden, Alexander/0000-0002-5698-8973 1467-8519 Si PY - 2018 SN - 0269-9702 SP - 602-610 ST - Cosmetic dentistry: A socioethical evaluation T2 - Bioethics TI - Cosmetic dentistry: A socioethical evaluation UR - ://WOS:000450332600009 VL - 32 ID - 1984 ER - TY - JOUR AB - It is well established that many systemic adverse health conditions have manifestations in the oral cavity. The purpose of this paper is to summarize the available scientific evidence that describes the opposite effect, how adverse oral health conditions affect three aspects of daily living: 1) systemic health, 2) quality of life, and 3) economic productivity. Examples of oral health affecting systemic health include rheumatic fever patients who develop infective endocarditis from oral bacteria and organ transplant patients who develop severe complications from oral infections. Both systemic health and quality of life are compromised when edentulousness, xerostomia, soft tissue lesions, or poorly fitting dentures affect eating and food choices. Conditions such as oral clefts, missing teeth, severe malocclusion, or severe caries are associated with feelings of embarrassment, withdrawal, and anxiety. Oral and facial pain from dentures, temporomandibular joint disorders, and oral infections affect social interaction and daily behaviors. The results of oral disorders can be felt not only physically and socially but also economically in our society. Dental disease accounts for many lost work and school days. Lower wage earners and minorities are disproportionately affected. Although there are many studies that evaluate these relationships, most are case reports, cross-sectional studies, or studies restricted to small or unique population groups. Lack of standardized measurements make comparisons across studies difficult. More population-based and longitudinal studies are needed to better understand the nature of these relationships. AD - Department of Dental Ecology, School of Dentistry, University of North Carolina at Chapel Hill 27599-7450. AN - 8263237 AU - Hollister, M. C. AU - Weintraub, J. A. DA - Dec DP - NLM ET - 1993/12/01 IS - 12 KW - Absenteeism Aged Bacteremia/etiology Child Child, Preschool Chronic Disease *Cost of Illness *Dental Health Surveys Efficiency Endocarditis, Bacterial/etiology Facial Pain/complications Focal Infection, Dental *Health Status Heart Diseases/etiology Humans *Mouth Diseases/complications/economics/psychology Nutrition Disorders/etiology Opportunistic Infections/etiology *Quality of Life Social Isolation United States LA - eng N1 - Hollister, M C Weintraub, J A Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Review United States J Dent Educ. 1993 Dec;57(12):901-12. PY - 1993 SN - 0022-0337 (Print) 0022-0337 SP - 901-12 ST - The association of oral status with systemic health, quality of life, and economic productivity T2 - J Dent Educ TI - The association of oral status with systemic health, quality of life, and economic productivity VL - 57 ID - 3386 ER - TY - JOUR AB - In childhood, burn or scald injuries are comparatively common, and the greatest risk is to infants and toddlers. The extent and severity of injuries can vary greatly, which can significantly affect recovery and outcome. To provide high quality nursing care to the child who has sustained a burn injury and the family, the children's nurse should understand the pathophysiology of the trauma and the associated physical and psychological suffering. Evidence-based nursing management of these aspects is an essential component of recovery. Children's nurses working in hospitals, schools or in the community can engage with parents, families, school staff and children to provide information, advice, and health and safety promotion for burn prevention. AD - Trinity College Dublin, Ireland. AN - 24617891 AU - Hollywood, E. AU - O'Neill, T. DA - Mar DO - 10.7748/ncyp2014.03.26.2.28.e396 DP - NLM ET - 2014/03/13 IS - 2 KW - Bandages Burns/complications/*nursing/physiopathology/psychology Child Child, Preschool Evidence-Based Nursing Fluid Therapy Humans Infant *Nursing Assessment Nutritional Support Pain Management/methods Pediatric Nursing LA - eng N1 - Hollywood, Eleanor O'Neill, Tracey Journal Article England Nurs Child Young People. 2014 Mar;26(2):28-33. doi: 10.7748/ncyp2014.03.26.2.28.e396. PY - 2014 SN - 2046-2336 (Print) 2046-2336 SP - 28-33 ST - Assessment and management of scalds and burns in children T2 - Nurs Child Young People TI - Assessment and management of scalds and burns in children VL - 26 ID - 3601 ER - TY - JOUR AB - Aim: The aim of this study was to describe a paediatric primary care pain sample and examine associations between pain, health-related quality of life and disability. Methods: The study design is descriptive and cross-sectional. One hundred and fifty-four consecutive children and adolescents between the ages of 8 and 16 seeking care for a pain-related conditions participated in this study. Pain characteristics, health-related quality of life and disability were investigated. Results: Eighty-seven per cent of participants had a pain duration of 3 months or more, and almost half of the group studied had a pain duration of = 12 months. The disability levels in the study group as a whole were low, with a mean FDI of 10.4 (SD 7.6). However, 35% of the study group had moderate disability levels and reported a mean FDI of 18.7 (SD 4.8). Single pain location was reported in 42%, whereas 58% had two or more pain locations. The children with multiple pain locations reported lower health-related quality of life and higher disability than children with single pain location. Conclusion: Paediatric pain patients in primary care consist partly of patients only slightly influenced by pain and partly of patients for whom pain has a great impact on their lives. AN - WOS:000310868300029 AU - Holm, S. AU - Ljungman, G. AU - Soderlund, A. DA - Dec DO - 10.1111/j.1651-2227.2012.02829.x IS - 12 N1 - Holm, Sara Ljungman, Gustaf Soderlund, Anne Ljungman, Gustaf/0000-0002-4949-2494; Soderlund, Anne/0000-0002-4537-030X PY - 2012 SN - 0803-5253 SP - 1246-1252 ST - Pain in children and adolescents in primary care; chronic and recurrent pain is common T2 - Acta Paediatrica TI - Pain in children and adolescents in primary care; chronic and recurrent pain is common UR - ://WOS:000310868300029 VL - 101 ID - 2405 ER - TY - JOUR AB - Aim: To assess recurrent subjective health complaints in Swedish schoolchildren with attention-deficit/hyperactivity disorder (ADHD). Methods: Cohort study of 577 fourth-graders (10-y-olds) in one municipality in Stockholm County. All children were screened for attention and behaviour problems through interviews with their parents and teachers. Children with high scores underwent further clinical and cognitive assessments. Information about health complaints was collected from the children themselves in a classroom questionnaire. The 516 children for whom there was information from all three data sources were included in the final study population. Hypotheses were tested in multivariate analyses with adjustment for sex and parental education. Results: Recurrent abdominal pain ( RAP), sleeping problems and tiredness were associated with ADHD ( stratified relative risks: 2.2 [1.4 - 3.4], 1.7 [1.1 - 2.7] and 2.7 [1.7 - 4.1], respectively), while there was no association with headache. Conclusion: This study indicates that treatment strategies for children with ADHD need to include an effective evaluation and treatment of RAP, tiredness and sleeping disturbances. Evaluation of ADHD should be considered in children with recurrent health complaints. AN - WOS:000238197800005 AU - Holmberg, K. AU - Hjern, A. DA - Jun DO - 10.1080/08035250600717121 IS - 6 N1 - Holmberg, Kirsten Hjern, Anders Hjern, Anders/0000-0002-1645-2058 1651-2227 PY - 2006 SN - 0803-5253 SP - 664-670 ST - Health complaints in children with attention-deficit/hyperactivity disorder T2 - Acta Paediatrica TI - Health complaints in children with attention-deficit/hyperactivity disorder UR - ://WOS:000238197800005 VL - 95 ID - 2730 ER - TY - JOUR AB - Objectives: The association between socioeconomic status and recurrent abdominal pain (RAP) among adolescents is an understudied issue. No study has examined whether such an association changes over time. The aim was to examine trends in RAP among adolescents in Denmark from 1991 to 2018, to examine whether there was social inequality in RAP and whether this inequality varied over time. Methods: The study used data from the Danish part of the international Health Behaviour in School-aged Children (HBSC) study of nationally representative samples of 11-, 13- and 15-year-olds. This study pooled data from eight comparable surveys from 1991 to 2018, overall participation rate 88.0%, n=30,048. The definition of RAP was self-reported stomach-ache daily or several days per week during the past six months. We reported absolute inequality as prevalence difference in RAP between low and high socioeconomic status and relative inequality as odds ratio for RAP by socioeconomic status. Results: In the entire study population, 5.6% reported RAP, 3.1% among boys and 7.8% among girls. There was a significant increase in RAP from 1991 to 2018 among boys and girls, test for trend, p<0.0001. The prevalence of RAP was significantly higher in low than high socioeconomic status, OR=1.63 (95% CI: 1.42-1.87). The absolute social inequality in RAP fluctuated with no consistent increasing or decreasing pattern. Conclusions: The prevalence of RAP increased from 1991 to 2018. The prevalence was significantly higher among girls than among boys, and significantly higher in low socioeconomic status families. Professionals should be aware of RAP as common and potentially serious health problems among children and adolescents. In addition to clinical examination it is important to focus on improving the child's quality of life, reduce parents' and children's concerns about the seriousness of the condition, and consider supplements to medicine use. AN - WOS:000609029800011 AU - Holstein, B. E. AU - Damsgaard, M. T. AU - Ammitzboll, J. AU - Madsen, K. R. AU - Pedersen, T. P. AU - Rasmussen, M. DA - Jan DO - 10.1515/sjpain-2020-0062 IS - 1 N1 - Holstein, Bjorn E. Damsgaard, Mogens Trab Ammitzboll, Janni Madsen, Katrine Rich Pedersen, Trine Pagh Rasmussen, Mette ; Holstein, Bjorn/G-6383-2013 Madsen, Katrine Rich/0000-0002-6591-9849; Pedersen, Trine Pagh/0000-0003-4622-6534; Damsgaard, Mogens Trab/0000-0003-4052-1831; Holstein, Bjorn/0000-0002-4348-280X 1877-8879 PY - 2021 SN - 1877-8860 SP - 95-102 ST - Recurrent abdominal pain among adolescents: trends and social inequality 1991-2018 T2 - Scandinavian Journal of Pain TI - Recurrent abdominal pain among adolescents: trends and social inequality 1991-2018 UR - ://WOS:000609029800011 VL - 21 ID - 1771 ER - TY - JOUR AB - Background To reduce the social burden of knee osteoarthritis (OA) by addressing it in the early stages in the population at greatest risk, the epidemiology of knee OA needs to be understood and associated demographic factors need to be identified. Objectives We evaluated the weighted prevalence of and demographic factors associated with radiographic knee OA in Korean adults. Methods We analyzed data from 12,287 individuals aged. 50 years who had radiographs of the knee taken in the 2010-2013 Korea National Health and Nutrition Examination Survey (KNHANES). Radiographic knee OA was defined based on the Kellgren-Lawrence grade, as follows: 0: No abnormal finding 1: Mild degenerative changes, minute osteophytes 2: Mild knee OA, definite osteophytes 3: Moderate knee OA, moderate joint-space narrowing and definite osteophytes 4: Severe knee OA, severe joint-space narrowing with subchondral sclerosis. Results We found that the prevalence of radiographic knee OA in the Korean adult population was 35.1%. Logistic regression analyses were performed to identify factors associated independently with radiographic knee OA, with age, sex, area of residence, education level, household income, and obesity serving as covariates. Women were at greater risk than men of having knee OA (OR 2.12, 95% CI 1.90-2.37, p < 0.001). Compared with subjects aged 50-59 years, adults aged. 80 years were at 8.87-fold (95% CI 7.12-11.06, p < 0.001) greater risk of having knee OA. Residence in a rural area was associated with a greater risk of having radiographic knee OA than was residence in an urban area (OR 1.26, 95% CI 1.0-81.48, p = 0.004), regardless of knee OA severity (Kellgren-Lawrence grades >= 2, >= 3, and 4). Elementary school graduates had 1.71-fold (p < 0.001) greater risks of having knee OA than did college graduates. Household incomes <= 24th percentile were associated with a greater risk of having knee OA compared with those >= 75th percentile (OR 1.28, 95% CI 1.08-1.52, p = 0.004). Obesity was associated with an approximately two-fold greater risk of knee OA, regardless of knee OA severity (Kellgren-Lawrence grades >= 2, >= 3, and 4). Conclusions Using data from the 2010-2013 KNHANES and defining knee OA as Kellgren-Lawrence grade >= 2, we found that the prevalence of radiographic knee OA was 35.1% (24.4% in men, 44.3% in women) in a representative sample of Korean adults aged >= 50 years, with the highest prevalence (78.7%) observed in women aged >= 80 years. Low socioeconomic status and traditional factors, including age, female sex, and obesity, were associated with the risk of knee OA. AN - WOS:000535303100040 AU - Hong, J. W. AU - Noh, J. H. AU - Kim, D. J. C7 - e0230613 DA - Mar DO - 10.1371/journal.pone.0230613 IS - 3 N1 - Hong, Jae Won Noh, Jung Hyun Kim, Dong-Jun Noh, Junghyun/AAU-8113-2020 PY - 2020 SN - 1932-6203 ST - The prevalence of and demographic factors associated with radiographic knee osteoarthritis in Korean adults aged >= 50 years: The 2010-2013 Korea National Health and Nutrition Examination Survey T2 - Plos One TI - The prevalence of and demographic factors associated with radiographic knee osteoarthritis in Korean adults aged >= 50 years: The 2010-2013 Korea National Health and Nutrition Examination Survey UR - ://WOS:000535303100040 VL - 15 ID - 1835 ER - TY - JOUR AB - BACKGROUND: Paediatric pain management remains a challenge in clinical settings. Parents can contribute to the effective and accurate pain assessment and management of their child. No systematic reviews regarding the parental involvement in their child's post-operative pain management have been published. OBJECTIVE: To determine the best available evidence regarding parental involvement in managing their children's post-operative pain in the hospital setting. INCLUSION CRITERIA: The review considered studies that included parents of all ethnic groups with children aged between 6 to 12 years old who were hospitalised and undergone surgery of any kind with post-operative surgical or incision site pain where care was provided in acute hospital settings. The phenomena of interest were the experiences of parents in managing their children's post-operative pain. SEARCH STRATEGY: A three-step search strategy was utilised in each component of this review. Major databases searched included: MEDLINE, CINAHL, Scopus, ScienceDirect, the Cochrane library, PubMed as well as Google Scholar. The search included published studies and papers in English from 1990 to 2009. METHODOLOGICAL QUALITY: Each included study was assessed by two independent reviewers using the appropriate appraisal checklists developed by the Joanna Briggs Institute (JBI). DATA COLLECTION: Quantitative and qualitative data were extracted from the included papers using standardised data extraction tools from the JBI, Meta-analysis Statistics Assessment and Review Instrument data extraction tool for descriptive/case series and the JBI-Qualitative Assessment and Review Instrument data extraction tool for interpretive and critical research. DATA SYNTHESIS: The five quantitative studies included in this review were not suitable for meta-analysis due to clinical and methodological heterogeneity and therefore the findings are presented in a narrative form. The two qualitative studies were from the same study, therefore meta-synthesis was not possible. Hence the results of the studies were presented in a narrative format. RESULTS: Seven papers were included in this review. The evidence identified topics including: pharmacological and non-pharmacological interventions carried out by parents; the experience of concern, fear, helplessness, anxiety, depression, frustration and lack of support felt by parents during their child's hospitalisation; communication issues and knowledge deficits; need for information by parents to promote effective participation in managing their child's post-operative pain. CONCLUSION: This review revealed pharmacological and non-pharmacological interventions carried out by parents to alleviate their children's post-operative pain. Obstacles and promoting factors influencing parents' experiences as well as their needs in the process of caring were identified. IMPLICATIONS FOR PRACTICE: Parents' roles in their child's surgical pain management should be clarified and their efforts acknowledged, which will encourage parents' active participation in their child's caring process. Nurses should provide guidance, education and support to parents. IMPLICATIONS FOR RESEARCH: More studies are needed to examine parents' experiences in caring for their child, investigate the effectiveness of education and guidance provided to parents by the nurses and explore the influence of parents' cultural values and nurses' perceptions of parental participation in their child's care. AD - 1. National University of Singapore & Centre for Evidence-based Nursing, National University Hospital, Singapore: A Collaborating Centre of the Joanna Briggs Institute. AN - 27820216 AU - Hoon, L. S. AU - Hong-Gu, H. AU - Mackey, S. DO - 10.11124/01938924-201109280-00001 DP - NLM ET - 2011/01/01 IS - 28 LA - eng N1 - Hoon, Lim Siew Hong-Gu, He Mackey, Sandra Journal Article Australia JBI Libr Syst Rev. 2011;9(28):1193-1225. doi: 10.11124/01938924-201109280-00001. PY - 2011 SN - 1838-2142 (Print) 1838-2142 SP - 1193-1225 ST - Parental involvement in their school-aged children's post-operative pain management in the hospital setting: a comprehensive systematic review T2 - JBI Libr Syst Rev TI - Parental involvement in their school-aged children's post-operative pain management in the hospital setting: a comprehensive systematic review VL - 9 ID - 4216 ER - TY - JOUR AB - BACKGROUND AND OBJECTIVE: As epidemiological data on prevalence of weather-related health effects were lacking we conducted a weather sensitivity (WS) survey in Germany. SUBJECTS AND METHODS: A total of 1064 citizens (age > 16) representative of the population in Germany were interviewed in January 2001. RESULTS: The results show that 19.2% of the population believe that weather influences their health to a "high degree", 35.3% that weather has "some influence on their health". The highest prevalence of WS (high + some influence) is found in the age group of > 60 years, in 68% of the subjects. The highest frequencies of weather-related symptoms are reported for stormy weather (30%) and when it gets colder (29%). The most frequent symptoms reported by weather-sensitive subjects are headaches/migraine (61%), lethargy (47%), sleep disturbances (46%), fatigue (42%), joint pain (40%), irritation (31%), depression (27%), vertigo (26%), concentration problems (26%) and scar pain (23%). 32% of the weather-sensitive subjects have been incapable to do their regular work because of weather-related symptoms at least once last year, 22% even several times. Co-morbidity was significantly higher in weather-sensitive subjects. CONSEQUENCE: On the basis of these data we are planning studies on causal factors of weather-related health effects. AD - Institut und Poliklinik für Arbeits- und Umweltmedizin der Ludwig-Maximilians-Universität, München. phoeppe@arbeits.med.uni-muenchen.de AN - 11905224 AU - Höppe, P. AU - von Mackensen, S. AU - Nowak, D. AU - Piel, E. DA - Jan 4 DO - 10.1055/s-2002-19429 DP - NLM ET - 2002/03/22 IS - 1-2 KW - Absenteeism Adolescent Adult Aged Cross-Sectional Studies Environmental Illness/*epidemiology/etiology Female Germany/epidemiology *Health Status Humans Incidence Male Middle Aged Occupational Diseases/epidemiology/etiology Somatoform Disorders/*epidemiology/etiology *Weather LA - ger N1 - Höppe, P von Mackensen, S Nowak, D Piel, E English Abstract Journal Article Germany Dtsch Med Wochenschr. 2002 Jan 4;127(1-2):15-20. doi: 10.1055/s-2002-19429. OP - Prävalenz von Wetterfühligkeit in Deutschland. PY - 2002 SN - 0012-0472 (Print) 0012-0472 SP - 15-20 ST - [Prevalence of weather sensitivity in Germany] T2 - Dtsch Med Wochenschr TI - [Prevalence of weather sensitivity in Germany] VL - 127 ID - 3752 ER - TY - JOUR AB - OBJECTIVE: To determine the pattern of headache and its associated symptoms in school going children. METHODS: The data of all the school going children attending the Headache Clinic in the Dept. of Neurology, Dhaka Medical College Hospital were retrospectively reviewed. A total of 1021 patients from October 1996 to September 2011 were selected. Data were collected through a predesigned questionnaire containing information on age, sex, social status, clinical features, opthalmoscopic findings, management, and in selected cases imaging results. RESULT: The mean age of headache in school children was 12.6±1.08 years with relatively older age of presentation among girls. The sex ratio was 1.64:1 in favor of girls at older age. Tension type headache (71.1%) was the most common form of headache, followed by migraine (18.4%) and mixed headache (6.7%). Though the girls had more frequent headache of both tension type (59.4%) and migraine (68.1%) variety, the latter was significantly associated in girls (p<0.001). Headache was of moderate severity in 53.3%, whereas severe headache was experienced by 19.9% of the children. The children commonly had nausea and/or vomiting (47.2%), as well as photophobia (24.7%) with headache. Mental stress (34%) and sunlight (30.9%) were common triggering factors whereas a sound sleep relieved headache in the majority (59.4%). Paracetamol (83.3%) and nortryptyline (62.8%) were the most commonly prescribed drug taken by them. CONCLUSION: Headache is a major health problem in school children, apart from other common health issues at this age. With increasing age, the girls more commonly suffer not only from migraine but also with other chronic headache. The direct causal association is yet to be determined. AD - Department of Neurology, Dhaka Medical College Hospital, Dhaka, Bangladesh. AN - 23074548 AU - Hoque, M. A. AU - Rahman, K. M. AU - Haque, B. AU - Chowdhury, R. N. AU - Khan, S. U. AU - Hasan, A. H. AU - Mondol, M. B. AU - Habib, M. AU - Mohammad, Q. D. C2 - PMC3472579 DA - Sep DO - 10.5001/omj.2012.95 DP - NLM ET - 2012/10/18 IS - 5 KW - Headache Tension type headache (TTH) migraine LA - eng N1 - 2070-5204 Hoque, Md Azharul Rahman, Kazi Mohibur Haque, Badrul Chowdhury, Rajib Nayan Khan, Sharif Uddin Hasan, Atm Hasibul Mondol, Md Badrul Alam Habib, Monsur Mohammad, Quazi Deen Journal Article Oman Med J. 2012 Sep;27(5):383-7. doi: 10.5001/omj.2012.95. PY - 2012 SN - 1999-768X (Print) 1999-768x SP - 383-7 ST - Pattern of headache in school going children attending specialized clinic in a tertiary care hospital in bangladesh T2 - Oman Med J TI - Pattern of headache in school going children attending specialized clinic in a tertiary care hospital in bangladesh VL - 27 ID - 4217 ER - TY - JOUR AB - Objective: Evidence from adult samples suggests a co-occurrence between pain and alcohol abuse. However, studies in adolescents are scarce and results are inconsistent, with some studies observing heightened and others observing reduced alcohol consumption in adolescents suffering from pain. We hypothesized that in adolescents the association between pain and alcohol use will be moderated by drinking motives. Methods: Data from a large representative sample of Flemish school children and adolescents (N = 10,650, 50.8% boys, age range = 10-21 years, Mage = 14.33 years) were collected as part of the World Health Organization collaborative Health Behaviour in School-Aged Children (HBSC) survey. Pain severity was graded based on a pediatric pain classification system that accounts for both pain intensity and disability. Alcohol consumption was operationalized using two variables: frequency of drinking and drunkenness. The Drinking Motives Questionnaire-Revised was used to capture drinking motives; it assesses four motive categories (enhancement, coping, social, and conformity). Results: Findings indicated that higher pain severity was associated with greater frequency of alcohol use and drunkenness. However, drinking motives moderated this association. The positive association between pain severity and drinking frequency was stronger in case of high conformity motives. Likewise, the association between pain severity and drunkenness frequency was stronger at high levels of conformity motives and reached significance only at high levels of coping motives. Conclusions: Our findings suggest that specific drinking motives are linked to problematic alcohol use in adolescents with pain. Future studies using a longitudinal design are needed to draw conclusions about direction of effects. AU - Horn-Hofmann, Claudia AU - Trost, Zina AU - Hublet, Anne AU - Mrug, Sylvie AU - Van Damme, Joris AU - Vervoort, Tine DA - 2018/02/01/ DO - 10.1093/pm/pnx016 DP - PubMed IS - 2 J2 - Pain Med KW - Adolescent Adolescents Alcohol Alcohol Drinking Alcoholic Intoxication Belgium Child Chronic Pain Drinking Motives Female Humans Male Motivation Pain Pediatric Pain Young Adult LA - eng PY - 2018 SN - 1526-4637 SP - 284-296 ST - The Relationship Between Pain Severity and Alcohol Use Among School-Aged Children and Adolescents T2 - Pain Medicine (Malden, Mass.) TI - The Relationship Between Pain Severity and Alcohol Use Among School-Aged Children and Adolescents: The Moderating Role of Drinking Motives UR - http://www.ncbi.nlm.nih.gov/pubmed/28340189 VL - 19 ID - 68 ER - TY - JOUR AB - AIM: To assess the efficacy of glucomannan (GNN) as the sole treatment for abdominal pain-related functional gastrointestinal disorders (FGIDs). METHODS: We conducted a double-blind, placebo-controlled, randomized trial. Patients were recruited among children referred to the Department of Paediatrics, Medical University of Warsaw. Included in the study were children aged 7-17 years with abdominal pain-related FGIDs classified according to the Rome. diagnostic criteria. The children were randomly assigned to receive GNN, a polysaccharide of 1,4-D-glucose and D-mannose, a soluble fiber from the Japanese Konjac plant, at a dosage of 2.52 g/d (1 sachet of 1.26 g 2 times a day), or a comparable placebo (maltodextrin) at the same dosage. The content of each sachet was dissolved in approximately 125 mL of fluid and was consumed twice daily for 4 wk. RESULTS: Of the 89 eligible children, 84 (94%) completed the study. "No pain" and "treatment success" (defined as no pain or a decrease >= 2/6 points on the FACES Pain Scale Revised) were similar in the GNN (n = 41) and placebo (n = 43) groups [no pain (12/41 vs 6/43, respectively; RR = 2.1, 95% CI: 0.87-5.07) as well as treatment success (23/41 vs 20/43; RR = 1.2, 95% CI: 0.79-1.83)]. No significant differences between the groups were observed in the secondary outcomes, such as abdominal cramps, abdominal bloating/gassiness, episodes of nausea or vomiting, or a changed in stool consistency. GNN demonstrated no significant influence on the number of children requiring rescue therapy, school absenteeism, or daily activities. CONCLUSION: In our setting, GNN, as dosed in this study, was no more effective than the placebo in achieving therapeutic success in the management of FGIDs in children. (C) 2013 Baishideng. All rights reserved. AN - WOS:000319869200009 AU - Horvath, A. AU - Dziechciarz, P. AU - Szajewska, H. DA - May DO - 10.3748/wjg.v19.i20.3062 IS - 20 N1 - Horvath, Andrea Dziechciarz, Piotr Szajewska, Hania Szajewska, Hania/M-4141-2018; Dziechciarz, Piotr/X-3659-2018; Horvath, Andrea/S-5069-2018 Szajewska, Hania/0000-0002-4596-2874; Dziechciarz, Piotr/0000-0003-4227-3130; Horvath, Andrea/0000-0001-9940-0001 2219-2840 PY - 2013 SN - 1007-9327 SP - 3062-3068 ST - Glucomannan for abdominal pain-related functional gastrointestinal disorders in children: A randomized trial T2 - World Journal of Gastroenterology TI - Glucomannan for abdominal pain-related functional gastrointestinal disorders in children: A randomized trial UR - ://WOS:000319869200009 VL - 19 ID - 2366 ER - TY - JOUR AB - Objective: To evaluate, in Canadian children with cerebral palsy (CP): (1) health-related quality of life (HRQoL) as well as (2) associations between HRQoL and (a) sleep problems, (b) nighttime pain, and (c) child characteristics (eg, age, CP phenotype, comorbidities). Methods: Children aged 3-12 years were recruited from neurology clinics and a provincial CP registry. Caregivers completed the Pediatric Quality of Life Inventory (PedsQL) Generic Core and CP Modules as well as the Sleep Disturbance Scale for Children (SDSC) to assess HRQoL and sleep, respectively. Child characteristics were extracted from hospital records and registry data. Results: A total of 146 children with CP (mean age +/- standard deviation: 6.9 +/- 2.9 years) completed the study. Impaired HRQoL (scores more than 2 SDs below the normative population mean) on the PedsQL Total, Physical and Psychosocial Health scales was found in 33.6%, 38.4% and 17.6% of children, respectively. Non-ambulatory status, sleep problems and significant comorbidity were the strongest predictors of impaired Total HRQoL, with odds ratios (95% confidence intervals) of 30.1 (8.2-110.4), 3.8 (1.1-12.5) and 3.3 (1.2-9.2), respectively, adjusted for young age (5-7 years) and nighttime pain. Non-ambulatory status and sleep problems exclusively increased the risk of impaired physical and psychological health, respectively, with adjusted ORs (95% CIs) of 58.3 (11.9-284.5) and 7.5 (2.5-22.5). More severe sleep problems were associated with worse pain-related HRQoL. Conclusions: Sleep, non-ambulatory status and presence of comorbidities are important determinants of HRQoL in children with CP. Monitoring sleep, psychosocial functioning and pain is important in this population, as their management should improve HRQoL. (c) 2018 Elsevier B.V. All rights reserved. AN - WOS:000458800800031 AU - Horwood, L. AU - Li, P. AU - Mok, E. AU - Oskoui, M. AU - Shevell, M. AU - Constantin, E. DA - Feb DO - 10.1016/j.sleep.2018.10.022 N1 - Horwood, Linda Li, Patricia Mok, Elise Oskoui, Maryam Shevell, Michael Constantin, Evelyn 1878-5506 PY - 2019 SN - 1389-9457 SP - 213-222 ST - Health-related quality of life in Canadian children with cerebral palsy: what role does sleep play? T2 - Sleep Medicine TI - Health-related quality of life in Canadian children with cerebral palsy: what role does sleep play? UR - ://WOS:000458800800031 VL - 54 ID - 1950 ER - TY - JOUR AB - To report on the differential diagnosis of lyme arthritis and synovial hemangioma due to similar clinical and radiological signs and symptoms. A 15-year-old boy presented at the age of 9 with recurrent rather painless swelling of the right knee. Altogether four episodes lasting for 1-2 weeks each occurred over a period of 18 months before medical advice was sought. Physical examination revealed only a slightly limited range of motion. Living in an endemic area of borreliosis, he reported a tick bite 6 months prior to onset of his symptoms with erythema migrans and was treated for 10 days with amoxicillin. Serology revealed two positive unspecific bands in IgG immunoblot (p41 and 66) with slight positivity for ELISA. Ultrasound revealed synovial thickening and increased fluid. Despite the weak positive serology a diagnosis of lyme arthritis could not be excluded and intravenous antibiotic treatment with ceftriaxone was started. After two further relapses antiinflammatory therapy including intraarticular steroids were introduced with no long lasting effect. A chronical disease developed with alternate periods of swelling and almost complete remission. Ultrasound as well as MRI demonstrated ongoing signs of synovitis, therefore after further progression, a diagnostic arthroscopy was performed showing an inconspicuous knee joint. A second MRI showed focal suprapatellar enhancement and was followed by open arthrotomy revealing a histopathological proven synovial cavernous juxtaarticular hemangioma. To our knowledge, the differential diagnosis of lyme arthritis and synovial hemangioma has not yet been reported despite obvious clinical similarities. In conclusion, in children and adolescents synovial hemangioma has to be considered in differential diagnosis of recurrent knee swelling. Early diagnosis is important to prevent prolonged suffering from chronic joint swelling with probable joint damages, unnecessary treatment procedures and as well school and sports absenteeism. AN - WOS:000297345900019 AU - Hospach, T. AU - Langendorfer, M. AU - Kalle, T. V. AU - Tewald, F. AU - Wirth, T. AU - Dannecker, G. E. DA - Dec DO - 10.1007/s00296-009-1320-x IS - 12 N1 - Hospach, Toni Langendoerfer, M. Kalle, T. V. Tewald, F. Wirth, T. Dannecker, G. E. 1437-160x PY - 2011 SN - 0172-8172 SP - 1639-1643 ST - Mimicry of lyme arthritis by synovial hemangioma T2 - Rheumatology International TI - Mimicry of lyme arthritis by synovial hemangioma UR - ://WOS:000297345900019 VL - 31 ID - 2468 ER - TY - JOUR AB - OBJECTIVE: To test the hypotheses that children with abdominal pain have anxious parents and come from families with high rates of physical illness and that they grow up to suffer from high rates of medically unexplained symptoms and psychiatric disorders. DESIGN: Population based birth cohort study. SETTING: General population. SUBJECTS: Participants in the Medical Research Council (MRC) national survey of health and development, a population based birth cohort study established in 1946. MAIN OUTCOME MEASURES: Abdominal pain present throughout childhood in the absence of defined organic disease, and measures of physical symptoms and psychiatric disorder at age 36 years. RESULTS: There were high rates of complaints about physical health among the parents of children with persistent abdominal pain, and the mothers had higher neuroticism scores. Children with persistent abdominal pain were more likely to suffer from psychiatric disorders in adulthood (odds ratio 2.72 (95% confidence interval 1.65 to 4.49)) but were not especially prone to physical symptoms once psychiatric disorder was controlled for (odds ratio 1. 39 (0.83 to 2.36)). CONCLUSIONS: Persistent abdominal pain is associated with poor health and emotional disorder in the parents. Children with abdominal pain do not necessarily continue to experience physical symptoms into adulthood but are at increased risk of adult psychiatric disorders. AD - Department of Psychological Medicine, King's College School of Medicine and Dentistry and Institute of Psychiatry, London SE5 8AZ, UK. m.hotopf@iop.bpmf.ac.uk AN - 9552994 AU - Hotopf, M. AU - Carr, S. AU - Mayou, R. AU - Wadsworth, M. AU - Wessely, S. C2 - PMC28520 DA - Apr 18 DO - 10.1136/bmj.316.7139.1196 DP - NLM ET - 1998/05/16 IS - 7139 KW - Abdominal Pain/*epidemiology Absenteeism Adolescent Adult Child Child, Preschool Chronic Disease Cohort Studies England/epidemiology Family Health Follow-Up Studies Humans Mental Disorders/*epidemiology Neurotic Disorders/epidemiology Prognosis Recurrence Scotland/epidemiology Sex Distribution Social Class Wales/epidemiology LA - eng N1 - 1468-5833 Hotopf, M Carr, S Mayou, R Wadsworth, M Wessely, S Journal Article Research Support, Non-U.S. Gov't BMJ. 1998 Apr 18;316(7139):1196-200. doi: 10.1136/bmj.316.7139.1196. PY - 1998 SN - 0959-8138 (Print) 0959-8138 SP - 1196-200 ST - Why do children have chronic abdominal pain, and what happens to them when they grow up? Population based cohort study T2 - Bmj TI - Why do children have chronic abdominal pain, and what happens to them when they grow up? Population based cohort study VL - 316 ID - 3374 ER - TY - JOUR AB - Children with physical disabilities are at a higher risk for sedentary living than their peers because of their physical limitations that then can lead to deterioration in physical functioning (Sit, McManus, McKenzie, & Lian, 2007). This deterioration then leads to more inactivity (Sit et al., 2007). Along with the typically discussed problems associated with inactivity, such as obesity and heart disease, those with disabilities are prone to secondary conditions such as chronic pain, extreme fatigue, weight and eating problems, muscle spasms, respiratory infections, falls or other injuries, mobility issues, asthma and social issues (e.g., Rimmer & Rowland, 2008; Rimmer, Yamaki, Davis, Wang & Vogel, 2011). According to McKenzie (2002), participation in moderate to vigorous physical activity (MVPA) during class is highly dependent upon how physical education subject matter is delivered (i.e., lesson context) and the instructor delivering it (i.e., teacher behavior) (McKenzie, 2002). Therefore, the purpose of this study was to observe and measure the physical activity (PA) levels of children with physical disabilities in inclusive physical education and recess settings. The results indicate that students with physical disabilities are engaged in MVPA for an average of 10.25% of the inclusive physical education class time, and 17.5% during inclusive recess. AN - WOS:000446903000011 AU - Houston, J. AU - van der Mars, H. AU - Lorenz, K. A. IS - 3 N1 - Houston, Jennifer van der Mars, Hans Lorenz, Kent A. 2372-1391 PY - 2018 SN - 8756-5811 SP - 51-57 ST - Physical Activity Patterns in Students with Physical Disabilities in General Physical Education and Inclusive Recess Settings T2 - Palaestra TI - Physical Activity Patterns in Students with Physical Disabilities in General Physical Education and Inclusive Recess Settings UR - ://WOS:000446903000011 VL - 32 ID - 2049 ER - TY - JOUR AB - Academic work as well as compensated employment has been found adversely associated with frequent headache; headache remains a costly disorder to the person and to society. However, little is known of factors-other than prior headache complaints-that may predict headache frequency over extended periods of time. Based on previous research, effortful task engagement appears to be a contributing factor to headache onset. This suggests that relatively stable attributes that are likely to affect effort expenditure may predict headache frequency over long intervals. The goal of this study was to evaluate the predictability of headache proneness in college-attending students by college aptitude tests administered in high school. Five hundred undergraduate students enrolled in a large public, urban university completed a number of questionnaires. Official admissions records of the college aptitude tests ACT (an acronym for the original test name, the American College Testing), SAT (the Scholastic Aptitude Test), and GPA (grade point average) were obtained and compared to the report of headache frequency. The ACT test mathematics predicted headache proneness in the hypothesized direction, while the ACT English test provided conflicting data; some evidence of gender differences was suggested. While nearly all research on headache and work effectiveness has considered headache to be a cause of reduced efficiency or productivity, this study suggests that a factor which presumably affects the ease of work completion (e.g., scholastic aptitude) may predict headache, at least in some cases within the "work" environment of academia. AN - WOS:000300160000011 AU - Hovanitz, C. A. AU - Thatcher, D. L. DA - Mar DO - 10.1007/s12529-010-9137-2 IS - 1 N1 - Hovanitz, Christine A. Thatcher, Dawn Lindsay PY - 2012 SN - 1070-5503 SP - 97-103 ST - Academic Aptitude as a Predictor of Headache Proneness During College: Could Headache be an Outcome of Low Test Scores? T2 - International Journal of Behavioral Medicine TI - Academic Aptitude as a Predictor of Headache Proneness During College: Could Headache be an Outcome of Low Test Scores? UR - ://WOS:000300160000011 VL - 19 ID - 2449 ER - TY - JOUR AB - Background and Aims: The aim of the present study was to evaluate proinflammatory and anti-inflammatory cytokine levels in children with irritable bowel syndrome (IBS). Patients and Methods: Thirty-five children with IBS (17 diarrhea-predominant, 7 constipation-predominant, and 11 mixed type) and 25 healthy children as healthy controls (HCs) were enrolled. All of the participants completed a questionnaire recording the duration, severity, and associated academic and social influences. Peripheral blood mononuclear cells were isolated and cultured for 24 hours with and without 1 or 5 ng/mL Escherichia coli lipopolysaccharide (LPS). Cytokine production including tumor necrosis factor-alpha (TNF-alpha), interleukin (IL)-6, and IL-10 was measured using enzyme-linked immunosorbent assays. Results: Children with IBS revealed lower baseline and significantly lower IL-10 levels after LPS stimulation compared with HCs (P = 0.001). Although not to a significant level, TNF-alpha and IL-6 levels were higher in children with IBS compared with HCs. The IL-10 levels in patients with IBS with strong pain intensity were lower both in baseline and under 1 ng/mL LPS stimulation. The levels became significantly lower under 5 ng/mL LPS stimulation compared with those experiencing mild and moderate pain intensity (P = 0.025). Conclusions: Our study suggests that children with IBS tend to produce lower amounts of the anti-inflammatory cytokine IL-10 at baseline and after LPS stimulation, implying that defects in immune modulation may contribute to IBS in children. AN - WOS:000288541100002 AU - Hua, M. C. AU - Lai, M. W. AU - Kuo, M. L. AU - Yao, T. C. AU - Huang, J. L. AU - Chen, S. M. DA - Apr DO - 10.1097/MPG.0b013e3181fd9816 IS - 4 N1 - Hua, Man-Chin Lai, Ming-Wei Kuo, Ming-Ling Yao, Tsung-Chieh Huang, Jing-Long Chen, Shu-Mei Huang, Jing-Long/0000-0002-3530-7753; Huang, Jing-Long/0000-0001-9280-920X 1536-4801 PY - 2011 SN - 0277-2116 SP - 376-381 ST - Decreased Interleukin-10 Secretion by Peripheral Blood Mononuclear Cells in Children With Irritable Bowel Syndrome T2 - Journal of Pediatric Gastroenterology and Nutrition TI - Decreased Interleukin-10 Secretion by Peripheral Blood Mononuclear Cells in Children With Irritable Bowel Syndrome UR - ://WOS:000288541100002 VL - 52 ID - 2505 ER - TY - JOUR AB - Background. Pain-related disability affects many children and adolescents suffering from chronic pain and may exert an impact on all areas of their lives. Reduction of pain-related disability is, therefore, a fundamental aim of treatment; however, no validated means exist to assess pain-related disability in children and adolescents. The aim of this study was to translate the Pediatric Pain Disability Index (P-PDI) of Varni into German and to investigate its psychometric qualities. Methods. Principal component and item analyses were conducted on outpatient (n=163) and inpatient samples (n=167) of adolescents suffering from chronic pain. Changes in pain-related disability 3 months after starting treatment were analysed in an outpatient sample of 110 adolescents. Correlations between pain-related disability, emotional variables and school absence as well as concordance with parents' ratings were investigated. Results. The P-PDI is a one-dimensional assessment tool with sufficient reliability. There were significant correlations between pain-related disability and pain intensity and school absence but not with pain duration, fear and depression. Parents and adolescents ratings correlated significantly, but 57% of parents underestimated the pain-related disability of their children. Conclusion. There is now a validated German version of the P-PDI to measure pain-related disability in adolescents suffering from chronic pain, which can be used in studies investigating treatment effectiveness. AN - WOS:000263523600003 AU - Hubner, B. AU - Hechler, T. AU - Dobe, M. AU - Damschen, U. AU - Kosfelder, J. AU - Denecke, H. AU - Schroeder, S. AU - Zernikow, B. DA - Feb DO - 10.1007/s00482-008-0730-0 IS - 1 N1 - Huebner, B. Hechler, T. Dobe, M. Damschen, U. Kosfelder, J. Denecke, H. Schroeder, S. Zernikow, B. 1432-2129 PY - 2009 SN - 0932-433X SP - 20-+ ST - Pain-related disability in adolescents suffering from chronic pain. Preliminary examination of the Pediatric Pain Disability Index (P-PDI) T2 - Schmerz TI - Pain-related disability in adolescents suffering from chronic pain. Preliminary examination of the Pediatric Pain Disability Index (P-PDI) UR - ://WOS:000263523600003 VL - 23 ID - 2618 ER - TY - JOUR AB - BACKGROUND: Between 4% and 25% of school-age children complain of recurrent abdominal pain (RAP) of sufficient severity to interfere with daily activities. It is unclear whether the diagnosis includes children with different aetiologies for their pain. For the majority no organic cause for their pain can be found on physical examination or investigation. Although most children are likely managed by reassurance and simple measures, a large range of interventions have been recommended. OBJECTIVES: To determine the effectiveness of dietary interventions for recurrent abdominal pain in school-age children. SEARCH STRATEGY: The Cochrane Library (CENTRAL) 2006 (Issue 4), MEDLINE (1966 to Dec 2006), EMBASE (1980 to Dec 2006), CINAHL (1982 to Dec 2007), ERIC (1966 to Dec 2006), PsycINFO (1872 to Dec 2006), LILACS (1982 to Dec 2006), SIGLE (1980 to March 2005), and JICST (1985 to 06/2000) were searched . Where appropriate, search filters were employed. In addition, researchers working in this area were asked to identify relevant studies. SELECTION CRITERIA: Randomised or quasi-randomised studies of any dietary treatment versus placebo or no treatment in school-age children with a diagnosis of RAP or functional gastrointestinal disorder based on the Rome II criteria. DATA COLLECTION AND ANALYSIS: Two authors independently assessed trials for inclusion, assessed quality and extracted data. Where appropriate studies were pooled using a random effects meta-analysis. MAIN RESULTS: Seven trials were included in this review. Two trials, including 83 participants, compared fibre supplements with placebo (Christensen 1982, Feldman 1985), with data from one study reported in two papers (Christensen 1982, Christensen 1986). The pooled odds ratio for improvement in the frequency of abdominal pain was 1.16 (95% CI 0.45-2.87). Two trials, including 90 participants (Lebenthal 1981, Dearlove 1983) compared lactose-containing with lactose-free diets. Neither reported data in a form which could be used in the meta-analysis and the former trial had a loss to follow-up of 45%. We were not able to obtain further data for either trial. Three trials (Bausserman 2005, Gavronska 2007, Young 1997) comparing supplementation with Lactobacillus with placebo met the inclusion criteria but only two (Bausserman 2005, Gavronska 2007), including a total of 168 children, provided analysable data. The pooled odds ratio for improvement of symptoms was 1.17 (95% CI 0.62, 2.21). AUTHORS' CONCLUSIONS: There is a lack of high quality evidence on the effectiveness of dietary interventions. This review provides no evidence that fibre supplements, lactose free diets or lactobacillus supplementation are effective in the management of children with RAP. AD - EGA Hospital, Neonatal Unit, UCLH, Huntley Street, London, UK WC1E 6DH. Angela.Huertas-Ceballos@uclh.nhs.uk AN - 18254014 AU - Huertas-Ceballos, A. AU - Logan, S. AU - Bennett, C. AU - Macarthur, C. DA - Jan 23 DO - 10.1002/14651858.CD003019.pub2 DP - NLM ET - 2008/02/07 IS - 1 KW - Abdominal Pain/*diet therapy Child Dietary Fiber/therapeutic use Humans Irritable Bowel Syndrome/*diet therapy Lactobacillus Lactose/administration & dosage Probiotics/therapeutic use Randomized Controlled Trials as Topic Recurrence LA - eng N1 - 1469-493x Huertas-Ceballos, A Logan, S Bennett, C Macarthur, C Journal Article Meta-Analysis Review Systematic Review England Cochrane Database Syst Rev. 2008 Jan 23;(1):CD003019. doi: 10.1002/14651858.CD003019.pub2. PY - 2008 SN - 1361-6137 SP - Cd003019 ST - Dietary interventions for recurrent abdominal pain (RAP) and irritable bowel syndrome (IBS) in childhood T2 - Cochrane Database Syst Rev TI - Dietary interventions for recurrent abdominal pain (RAP) and irritable bowel syndrome (IBS) in childhood ID - 3613 ER - TY - JOUR AB - BACKGROUND: Between 4% and 25% of school-age children complain of recurrent abdominal pain (RAP) of sufficient severity to interfere with daily activities. It is unclear whether the diagnosis includes children with different aetiologies for their pain. For the majority no organic cause for their pain can be found on physical examination or investigation. Although most children are likely managed by reassurance and simple measures, a large range of interventions have been recommended. OBJECTIVES: To determine the effectiveness of dietary interventions for recurrent abdominal pain in school-age children. SEARCH STRATEGY: The Cochrane Library (CENTRAL) 2006 (Issue 4), MEDLINE (1966 to Dec 2006), EMBASE (1980 to Dec 2006), CINAHL (1982 to Dec 2007), ERIC (1966 to Dec 2006), PsycINFO (1872 to Dec 2006), LILACS (1982 to Dec 2006), SIGLE (1980 to March 2005), and JICST (1985 to 06/2000) were searched . Where appropriate, search filters were employed. Researchers working in this area were asked to identify relevant studies. SELECTION CRITERIA: Randomised or quasi-randomised studies of any dietary treatment versus placebo or no treatment in school-age children with a diagnosis of RAP or functional gastrointestinal disorder based on the Rome II criteria. DATA COLLECTION AND ANALYSIS: Two authors independently assessed trials for inclusion, assessed quality and extracted data. Where appropriate studies were pooled using a random effects meta-analysis. MAIN RESULTS: Seven trials were included in this review. Two trials, including 83 participants, compared fibre supplements with placebo (Christensen 1982, Feldman 1985), with data from one study reported in two papers (Christensen 1982, Christensen 1986). The pooled odds ratio for improvement in the frequency of abdominal pain was 1.26 (0.25, 6.29). Two trials, including 90 participants (Lebenthal 1981, Dearlove 1983) compared lactose-containing with lactose-free diets. Neither reported data in a form which could be used in the meta-analysis and the former trial had a loss to follow-up of 45%. We were not able to obtain further data for either trial. Three trials (Bausserman 2005, Gavronska 2007, Young 1997) comparing supplementation with Lactobacillus with placebo met the inclusion criteria but only two (Bausserman 2005, Gavronska 2007), including a total of 168 children, provided analysable data. The pooled odds ratio for improvement of symptoms was 1.17 (95% CI 0.62, 2.21). AUTHORS' CONCLUSIONS: There is a lack of high quality evidence on the effectiveness of dietary interventions. This review provides no evidence that fibre supplements, lactose free diets or lactobacillus supplementation are effective in the management of children with RAP. AD - Neonatal Unit, EGA Hospital, UCLH, Huntley Street, London, UK, WC1E 6DH. Angela.Huertas-Ceballos@uclh.nhs.uk AN - 19160214 AU - Huertas-Ceballos, A. A. AU - Logan, S. AU - Bennett, C. AU - Macarthur, C. DA - Jan 21 DO - 10.1002/14651858.CD003019.pub3 DP - NLM ET - 2009/01/23 IS - 1 KW - Abdominal Pain/*diet therapy Child Dietary Fiber/therapeutic use Humans Irritable Bowel Syndrome/*diet therapy Lactobacillus Lactose/administration & dosage Probiotics/therapeutic use Randomized Controlled Trials as Topic Recurrence LA - eng N1 - 1469-493x Huertas-Ceballos, Angela A Logan, Stuart Bennett, Cathy Macarthur, Colin Journal Article Review Systematic Review England Cochrane Database Syst Rev. 2009 Jan 21;(1):CD003019. doi: 10.1002/14651858.CD003019.pub3. PY - 2009 SN - 1361-6137 SP - Cd003019 ST - Dietary interventions for recurrent abdominal pain (RAP) and irritable bowel syndrome (IBS) in childhood T2 - Cochrane Database Syst Rev TI - Dietary interventions for recurrent abdominal pain (RAP) and irritable bowel syndrome (IBS) in childhood ID - 3608 ER - TY - JOUR AB - Little is known about childhood and adolescent risk and prognostic factors for recurrent headaches. This systematic review 1) examined longitudinal evidence about factors associated with onset and course of recurrent headaches in childhood or adolescence, using meta analysis where possible, and 2) evaluated the quality of this evidence using a modified Grading of Recommendations Assessment, Development and Evaluation framework. Through searching electronic databases, reference lists of included studies, and an electronic mail list we identified and included 23 articles reporting 19 cohorts. From the included studies we explored 27 risk factors for recurrent headaches, 27 prognostic factors for persistence of recurrent headaches, and 6 prognostic factors for presence of headache-related disability. The quality of evidence for most associations is low or very low. There is moderate-quality evidence that women are at risk of developing recurrent headaches and of headaches persisting. There is high-quality evidence suggesting that children with negative emotional states manifested through anxiety, depression, or mental distress are not at risk of developing headache, but moderate-quality evidence suggests that the presence of comorbid negative emotional states in children with headaches is associated with increased risk of headache persistence. Because of the small number of studies, further investigation is needed to increase confidence in existing evidence and to explore new risk and prognostic factors. Perspective: This is a review of the evidence about childhood and adolescent risk and prognostic factors for the onset of recurrent headaches and their course. Understanding these factors can help identify childrens' risk and may suggest ways to reduce this risk. (C) 2016 by the American Pain Society AN - WOS:000381241800001 AU - Huguet, A. AU - Tougas, M. E. AU - Hayden, J. AU - McGrath, P. J. AU - Chambers, C. T. AU - Stinson, J. N. AU - Wozney, L. DA - Aug DO - 10.1016/j.jpain.2016.03.010 IS - 8 N1 - Huguet, Anna Tougas, Michelle E. Hayden, Jill McGrath, Patrick J. Chambers, Christine T. Stinson, Jennifer N. Wozney, Lori Huguet, Anna/AAI-3244-2021; Chambers, Christine T./ABA-9257-2020; Huguet, Anna/R-2666-2018 Chambers, Christine T./0000-0002-7138-916X; Wozney, Lori/0000-0001-6933-9596; McGrath, Patrick/0000-0002-9568-2571; Wozney, Lori/0000-0003-4280-3322; Huguet, Anna/0000-0002-4002-8644 1528-8447 PY - 2016 SN - 1526-5900 SP - 855-873 ST - Systematic Review of Childhood and Adolescent Risk and Prognostic Factors for Recurrent Headaches T2 - Journal of Pain TI - Systematic Review of Childhood and Adolescent Risk and Prognostic Factors for Recurrent Headaches UR - ://WOS:000381241800001 VL - 17 ID - 2154 ER - TY - JOUR AB - Objective: Many juveniles with chronic pain of no known organic cause recover. Because adolescents whose pain persists may have chronic pain as adults, a subsample of 42 adolescents from a prevalence study in which continuation of their pain was observed throughout the study period was investigated quantitatively and qualitatively. All mothers (n = 42) completed a questionnaire on the impact of the adolescent's pain on the family. The authors tested the hypothesis that pain parameters, pain-related quality of life, and impact of pain on the family would deteriorate over time. Design: Three-year follow-up questionnaires, diaries, and interviews were used. Setting: The study was conducted in the general population in the Rotterdam area. Participants: Adolescents (aged 12-18 years) who indicated chronic pain in our previous prevalence study and in a diary and questionnaire each year of the 3-year follow-up were included in the study. Results: The most prevalent pains were limb pain and headache. The pain intensity was mild (33 mm on a visual analog scale), very frequent (72% of all diary entries), and associated with relatively poor functional status and poor psychological and somatic functioning. The pain parameters, pain-related quality of life, and impact of pain on the family (i.e., restrictions in social life and problems in dealing with the stress of the adolescent's pain) remained surprisingly stable across the assessments. The interviews showed that pain had become part of the daily life of several adolescents, who structured their activities and sleeping hours to prevent aggravation of pain. In particular, adolescents with headache reported problems with cognitive activities, whereas those with limb pain and back pain reported problems with physical activities. Conclusions: For adolescents with persistent pain with no known organic cause, intensity and frequency of pain, quality of life, and impact of pain on the family did not change. Generally, they seemed to cope quite well with their pain. In view of these results, further studies should involve follow-up of adolescents with persistent pain into adulthood to establish the determinants of their pain and to find out whether they maintain their adaptive ways of living with their pain. AN - WOS:000174237600005 AU - Hunfeld, J. A. M. AU - Perquin, C. W. AU - Bertina, W. AU - Hazebroek-Kampschreur, Aajm AU - van Suijlekom-Smit, L. W. A. AU - Koes, B. W. AU - van der Wouden, J. C. AU - Passchier, J. DA - Mar-Apr DO - 10.1097/00002508-200203000-00005 IS - 2 N1 - Hunfeld, JAM Perquin, CW Bertina, W Hazebroek-Kampschreur, AAJM van Suijlekom-Smit, LWA Koes, BW van der Wouden, JC Passchier, J Koes, Bart w/K-4614-2016; van der Wouden, Johannes C/O-5109-2019; van der Wouden, Johannes C/C-2597-2009 Koes, Bart w/0000-0002-0450-9969; van der Wouden, Johannes C/0000-0001-6639-6050; PY - 2002 SN - 0749-8047 SP - 99-106 ST - Stability of pain parameters and pain-related quality of life in adolescents with persistent pain: A three-year follow-up T2 - Clinical Journal of Pain TI - Stability of pain parameters and pain-related quality of life in adolescents with persistent pain: A three-year follow-up UR - ://WOS:000174237600005 VL - 18 ID - 2836 ER - TY - JOUR AB - Objective: To study chronic pain not caused by somatic disease in adolescents and the effect of pain on the quality of life of the adolescents and their families. Methods: One hundred twenty-eight youngsters (12-18 years) who had reported chronic pain kept a 3-week diary of their pain and completed a questionnaire on quality of life. Their mothers completed a questionnaire on the impact of their youngster's pain on the family. Results: The most prevalent pains were limb pain, headache, abdominal, and back pain. The pain increased during the day, with the highest frequency around dinnertime and the highest intensity around bedtime. Girls reported more intense and more frequent pain than boys. The higher the intensity and frequency of the pain, the lower the self-reported quality of life of the female or male adolescent, especially regarding psychological functioning (e.g. feeling less at ease), physical status (a greater incidence of other somatic complaints), and functional status (more impediments to leisure and daily activities). Chronic pain also had a negative impact on family life. The mothers reported restrictions, particularly in social life, and problems dealing with the stress of the adolescent's pain. Conclusions: Chronic pain, not caused by somatic disease, was present to a higher degree in girls; the pain increased during the day and had a negative impact on quality of life of the adolescents and the family. There is a need for future research aimed at identifying risk factors for chronic pain and pain-associated quality of life in children and adolescents. AN - WOS:000168426800002 AU - Hunfeld, J. A. M. AU - Perquin, C. W. AU - Duivenvoorden, H. J. AU - Hazebroek-Kampschreur, Aajm AU - Passchier, J. AU - van Suijlekom-Smit, L. W. A. AU - van der Wouden, J. C. DA - Apr-May DO - 10.1093/jpepsy/26.3.145 IS - 3 N1 - Hunfeld, JAM Perquin, CW Duivenvoorden, HJ Hazebroek-Kampschreur, AAJM Passchier, J van Suijlekom-Smit, LWA van der Wouden, JC van der Wouden, Johannes C/O-5109-2019; van der Wouden, Johannes C/C-2597-2009 van der Wouden, Johannes C/0000-0001-6639-6050; PY - 2001 SN - 0146-8693 SP - 145-153 ST - Chronic pain and its impact on quality of life in adolescents and their families T2 - Journal of Pediatric Psychology TI - Chronic pain and its impact on quality of life in adolescents and their families UR - ://WOS:000168426800002 VL - 26 ID - 2852 ER - TY - JOUR AB - Object. In this descriptive study the authors evaluated medical outcomes, interventions, satisfaction with life, and subjective impressions about selective dorsal rhizotomy (SDR) in older adolescents and adults who had undergone the procedure as children. Methods. A survey was administered to older adolescents (16-20 years old) and adults with CP who had undergone SDR between 1986 and 2000 at two academic centers. The patients or their caregivers participated in telephone or clinic interviews. Subjective impressions about the SDR and a history of post-SDR medical interventions were obtained. Current functional status, history and ratings of pain, educational achievement, living situation, and subjective health status were also recorded. The Diener Satisfaction with Life Scale (SWLS) was administered. Results. Eighty-eight participants, mean age 25.6 +/- 4.8 years (mean +/- standard deviation), were interviewed at a mean of 19.6 +/- 3.0 years after surgery. The distribution of current reported Gross Motor Function Classification System levels was as follows: I, 7%; II, 18%; III, 23%; IV, 36%; and V, 16%. Moreover, 56% of respondents were living with parents and 25% were living alone. Thirty-five percent were employed, and 39% were still in school. The mean overall SWLS score was 26.0 +/- 7.3, indicating a high level of satisfaction with life. According to 65% of the patients, the SDR was helpful; 31% were uncertain about the procedure's efficacy. Sixty-five percent would recommend the procedure to others. Fifty-eight percent reported excellent to very good health. Forty-four percent reported pain in the past week. Fifty-one percent reported chronic back pain in general. Logistic regression analysis suggested that an increased satisfaction with life was a predictor (p = 0.01) of an affirmative response to the question about recommending the procedure to others and that better overall health showed a trend toward being such a predictor (p = 0.08). Additional interventions were frequently performed after the SDR. Seventy-four percent of participants underwent orthopedic surgery. Thirty-eight percent were currently taking oral medications for tone, and 53% had received botulinum toxin injections for spasticity treatment. Thirteen patients (15%) had an intrathecal baclofen pump placed. Conclusions. The majority of adults who had undergone SDR as children would recommend the procedure to others. Very few reported negative impressions of the procedure. Levels of satisfaction with life were generally high. Pain prevalence was similar to what has been reported in the literature for adults with cerebral palsy. Despite the SDR, further interventions, both surgical and nonsurgical, were used in the majority of patients. (http://thejns.org/doi/abs/10.3171/2013.1.PEDS12311) AN - WOS:000316715600003 AU - Hurvitz, E. A. AU - Marciniak, C. M. AU - Daunter, A. K. AU - Haapala, H. J. AU - Stibb, S. M. AU - McCormick, S. F. AU - Muraszko, K. M. AU - Gaebler-Spira, D. DA - Apr DO - 10.3171/2013.1.Peds12311 IS - 4 N1 - Hurvitz, Edward A. Marciniak, Christina M. Daunter, Alecia K. Haapala, Heidi J. Stibb, Stacy M. McCormick, Sarah F. Muraszko, Karin M. Gaebler-Spira, Deborah Gaebler-Spira, Deborah/0000-0001-6827-4241; Daunter, Alecia/0000-0002-3087-0934; Marciniak, Christina/0000-0003-3300-0050 PY - 2013 SN - 1933-0707 SP - 380-388 ST - Functional outcomes of childhood dorsal rhizotomy in adults and adolescents with cerebral palsy Clinical article T2 - Journal of Neurosurgery-Pediatrics TI - Functional outcomes of childhood dorsal rhizotomy in adults and adolescents with cerebral palsy Clinical article UR - ://WOS:000316715600003 VL - 11 ID - 2374 ER - TY - JOUR AB - Objectives: This study was undertaken to determine (1) the prevalence of gastrointestinal symptoms including abdominal pain in a community-based population of adolescents, (2) whether a subgroup of these subjects have symptoms resembling irritable bowel syndrome (IBS), and (3) whether anxiety and depression are more commonly found in adolescents with IBS-type symptoms compared with unaffected adolescents. Methods: We collected data by administration of a gastrointestinal symptoms questionnaire, State-Trait Anxiety Inventory, and Children's Depression Inventory to middle school and high school students. Results: A total of 507 subjects participated (mean age of middle school students 12.6 years; mean age of high school students 15.6 years), Abdominal pain was noted by 75% of all students. The pain occurred weekly in 13% to 17% of the subjects and was severe enough to affect activities in approximately 21%, Irritable bowel syndrome-type symptoms were noted by 17% of high school students and 8% of middle school students (p < 0.01) who reported abdominal pain (n = 381), representing 14% and 6% of all high school and middle school students (p < 0.005), respectively, Anxiety and depression scores were significantly higher for students with IBS-type symptoms compared with those without symptoms, Eight percent of all students had seen a physician for abdominal pain in the previous year, These visits were correlated with abdominal pain severity, frequency, duration, and disruption of normal activities but not with anxiety, depression, gender, family structure, or ethnicity. Conclusion: Recurrent abdominal pain and symptoms of IBS are commonly noted in a community-based adolescent population and frequently result in use of health care resources, Health care providers who work with this age group need to be able to recognize the symptom complex associated with IBS, as well as the possible relationship to anxiety and depression. AN - WOS:A1996VK79700007 AU - Hyams, J. S. AU - Burke, G. AU - Davis, P. M. AU - Rzepski, B. AU - Andrulonis, P. A. DA - Aug DO - 10.1016/s0022-3476(96)70246-9 IS - 2 N1 - Hyams, JS Burke, G Davis, PM Rzepski, B Andrulonis, PA 1097-6833 PY - 1996 SN - 0022-3476 SP - 220-226 ST - Abdominal pain and irritable bowel syndrome in adolescents: A community-based study T2 - Journal of Pediatrics TI - Abdominal pain and irritable bowel syndrome in adolescents: A community-based study UR - ://WOS:A1996VK79700007 VL - 129 ID - 2923 ER - TY - JOUR AB - Objective: Pain-associated disability syndrome (PADS) is a recently defined term that describes patients with chronic pain whose restriction in daily activities appears disproportionately severe for the observable pathology. The aim of this study is to describe the features of a group of pediatric patients with abdominal symptoms fitting this diagnosis. Methods: To identify factors associated with visceral PADS, we reviewed the records of 40 patients (18 males; age range, 7-21 years) with gastrointestinal symptoms severe enough to prevent school attendance or eating for 2 months or more. These patients, in whom pain was neither feigned nor self-induced, met the diagnostic criteria for visceral PADS, including failure of usual treatments and lack of a satisfactory organic explanation for the severity of the pain. Results: The dominant symptom was abdominal pain in 30 patients, regurgitation in 5 patients, nausea in 3 patients, and chest pain in 2 patients. All patients complained of pain or discomfort, and all met symptom-based criteria for one or more functional gastrointestinal disorder. Disordered sleep was a problem for 39 patients. Factors associated with PADS included learning disabilities, unrealistic goals in a perfectionist, high-achieving child, early pain experiences, passive or dependent coping, style, marital problems in the home, and chronic illness in a parent. All patients had at least two associated factors, and a majority had four or more associated factors. Possible triggering events included an acute febrile illness in 20 patients, school change in I I patients, trauma in 2 patients, death of a loved one ill 2 patients, and sexual abuse in 2 patients. Before diagnosis, all patients underwent extensive negative evaluations. Nearly all patients had mental health evaluations that ruled out eating disorder and psychosis. Medical management had failed, and surgeries worsened symptoms. In a majority of patients, we identified a comorbid psychiatric disorder. Conclusions: Evaluation of preteens and teens unable to go to school or eat because of unexplained incapacitating symptoms should include queries about factors associated with PADS. To treat PADS, medical and mental health clinicians must recognize pain as having both nociceptive and affective components and address treatment collaboratively. Invasive procedures and surgery reinforce the cycle of arousal and pain and are to be avoided. Age for the onset of PADS in the preteen and early teen years suggests that developmental issues play a role. (C) 2002 Lippincott Williams Wilkins, Inc. AN - WOS:000179616300014 AU - Hyman, P. E. AU - Bursch, B. AU - Sood, M. AU - Schwankovsky, L. AU - Cocjin, J. AU - Zeltzer, L. K. DA - Nov DO - 10.1097/00005176-200211000-00014 IS - 5 N1 - Hyman, PE Bursch, B Sood, M Schwankovsky, L Cocjin, J Zeltzer, LK Zeltzer, Lonnie/0000-0001-9306-9450 PY - 2002 SN - 0277-2116 SP - 663-668 ST - Visceral pain-associated disability syndrome: A descriptive analysis T2 - Journal of Pediatric Gastroenterology and Nutrition TI - Visceral pain-associated disability syndrome: A descriptive analysis UR - ://WOS:000179616300014 VL - 35 ID - 2819 ER - TY - JOUR AB - CONTEXT: Moderate to severe traumatic brain injuries can negatively influence health-related quality of life (HRQOL) in adolescent patients. The effect of sport-related concussion on adolescent HRQOL remains unclear. OBJECTIVE: To investigate the perceptions of adolescent student-athletes and their parents regarding the adolescents' HRQOL 1 year after sport-related concussion. DESIGN: Qualitative study. SETTING: Secondary school. PATIENTS OR OTHER PARTICIPANTS: Seven adolescent student-athletes (age range, 12-16 years) who sustained a sport-related concussion at least 1 year (15.3 ± 2.8 months) before the study participated along with their primary care-giving parents (n = 7). DATA COLLECTION AND ANALYSIS: Fourteen semistructured face-to-face interviews (7 adolescents, 7 parents) were completed. Interviews were transcribed and inductively analyzed by a team of 3 athletic trainers with 32 combined years of professional experience. Themes were negotiated through a consensual review process. Participant checks were completed to ensure trustworthiness of the results. RESULTS: Four major themes emerged from the interviews: (1) significant effect of symptoms, (2) feelings of frustration, (3) influence on school attendance and activities, and (4) nature of interpersonal and team relationships. Participants indicated that the physical symptoms of the concussion substantially affected their emotional and academic function. The influence of the concussion on social interactions seemed to depend on the nature of interpersonal relationships. CONCLUSIONS: Sport-related concussion can negatively influence physical and emotional function, academics, and interpersonal interactions as perceived by adolescent student-athletes and their parents. Education of parents and their children, school professionals, coaches, and teammates remains critical to effectively recognize and manage sport-related concussion. Secondary school districts also play a critical role in the concussion-management process by establishing and implementing accommodation policies that alleviate student concerns about falling behind while ensuring a healthy return to normal school routines. Furthermore, adolescent support systems must be considered throughout the recovery process. AD - Department of Health and Nutritional Sciences, South Dakota State University, Brookings. AN - 26509684 AU - Iadevaia, C. AU - Roiger, T. AU - Zwart, M. B. C2 - PMC4732398 DA - Nov DO - 10.4085/1062-6050-50.11.02 DP - NLM ET - 2015/10/29 IS - 11 KW - Adolescent Adolescent Health Athletes/psychology Athletic Injuries/complications/*psychology Brain Concussion/complications/*psychology Brain Injuries/*psychology Child Female Headache Disorders/etiology Humans Male Parents/psychology *Quality of Life Schools Sports/psychology Students/psychology/statistics & numerical data concussions postconcussion recovery secondary schools LA - eng N1 - 1938-162x Iadevaia, Cheree Roiger, Trevor Zwart, Mary Beth Journal Article Observational Study Research Support, Non-U.S. Gov't J Athl Train. 2015 Nov;50(11):1182-9. doi: 10.4085/1062-6050-50.11.02. Epub 2015 Oct 28. PY - 2015 SN - 1062-6050 (Print) 1062-6050 SP - 1182-9 ST - Qualitative Examination of Adolescent Health-Related Quality of Life at 1 Year Postconcussion T2 - J Athl Train TI - Qualitative Examination of Adolescent Health-Related Quality of Life at 1 Year Postconcussion VL - 50 ID - 3136 ER - TY - JOUR AB - OBJECTIVES: To quantify the social burden among Japanese migraine patients in the context of currently available migraine treatments, by comparison with non-migraine controls, and comparison of migraine patients currently taking prescription medication versus not taking prescription medication. DESIGN: Cross-sectional analysis. SETTING: Data from the population-based online self-administered Japan National Health and Wellness Survey (NHWS) 2017. PARTICIPANTS: Respondents to the NHWS (n=30 001) were ≥18 years. Migraine patients were respondents with self-reported experience and physician diagnosis of migraine. Non-migraine controls reported no migraine experience. Migraine patients were subgrouped into currently taking prescription medication for migraine (Rx) and currently not taking prescription medication (non-Rx). METHODS: One-way analysis of variance tests were performed to compare health-related quality of life (HRQoL), work productivity and activity impairment and healthcare resource utilisation between migraine patients and matched non-migraine controls selected by 1:1 propensity score matching. Generalised linear models were used to compare outcomes and migraine related characteristics between Rx and non-Rx. RESULTS: Compared with matched controls, migraine patients (n=1265) had significantly lower HRQoL in terms of lower Physical Component Summary (48.36 vs 51.29, p<0.001), Mental Component Summary (44.65 vs 48.31, p<0.001), Role/Social Component Summary (41.78 vs 46.18, p<0.001) and mean EuroQol 5-Dimension index (0.77 vs 0.86, p<0.001) scores. Migraine patients experienced significantly higher absenteeism (6.95% vs 3.07%, p<0.001), presenteeism (32.73% vs 18.94%, p<0.001), work productivity loss (34.82% vs 20.03%, p<0.001) and daily activity impairment (35.70% vs 22.04%, p<0.001) and visited healthcare professionals more often (8.38 vs 4.57, p<0.001) than controls. No significant differences in these outcomes were found when comparing Rx (n=587) and non-Rx (n=678) patients. CONCLUSIONS: There is an unmet need for improved HRQoL and work productivity in Japanese migraine patients despite the currently available prescription medications, which are important factors to consider for future development of migraine therapies. AD - Department of Internal Medicine, Headache Care Unit, Fujitsu Clinic, Kawasaki, Japan. Medicines Development Unit Japan, Eli Lilly Japan KK, Kobe, Japan ueda_kaname@lilly.com. Health Division, Kantar Health, Seoul, South Korea. Medicines Development Unit Japan, Eli Lilly Japan KK, Kobe, Japan. Health Division, Kantar Health, Singapore. AN - 33168555 AU - Igarashi, H. AU - Ueda, K. AU - Jung, S. AU - Cai, Z. AU - Chen, Y. AU - Nakamura, T. C2 - PMC7654137 DA - Nov 9 DO - 10.1136/bmjopen-2020-038987 DP - NLM ET - 2020/11/11 IS - 11 KW - Child Cost of Illness Cross-Sectional Studies Female Health Surveys Humans Japan/epidemiology *Migraine Disorders/diagnosis/drug therapy/epidemiology Quality of Life *health economics *migraine *public health honorarium from Pfizer, Eisai, Otsuka Pharmaceutical, Kyowa Kirin, Takeda Pharmaceutical, Amgen Astellas BioPharma, and Eli Lilly, outside the submitted work. KU, TK and ZC are full-time employees of Eli Lilly Japan KK. and share holders of Eli Lilly & Company. SJ and YC are full-time employees of Kantar, Health Division. LA - eng N1 - 2044-6055 Igarashi, Hisaka Ueda, Kaname Orcid: 0000-0003-1967-9829 Jung, Sungeun Cai, Zhihong Chen, Yirong Nakamura, Tomomi Journal Article Research Support, Non-U.S. Gov't BMJ Open. 2020 Nov 9;10(11):e038987. doi: 10.1136/bmjopen-2020-038987. PY - 2020 SN - 2044-6055 SP - e038987 ST - Social burden of people with the migraine diagnosis in Japan: evidence from a population-based cross-sectional survey T2 - BMJ Open TI - Social burden of people with the migraine diagnosis in Japan: evidence from a population-based cross-sectional survey VL - 10 ID - 3672 ER - TY - JOUR AB - On the basis of extended health balances of 3482 14-year old school children, the association between the incidence of chronic diseases of the nasopharynx and some circumstances of their living conditions was evaluated. Nasopharyngeal diseases were identified in 2.3% of children. Their incidence was unrelated to sex; it was similar in urban and rural environments. Some circumstances creating inferior living conditions were associated with higher incidence of these diseases; they included living in poverty, lack of central heating and covering by foot a large distance from home to school. Other circumstances, e.g. numerous family, crowding of the apartment, un-sanitary sleeping conditions, contrary to expectation failed to display such associations. Likewise, health-promoting behaviours (e.g. habit of teeth cleaning, practising sports) did not lead to lower incidence of these diseases. Consideration of the problem from standpoint of physical development showed that the proceeding of the maturation process failed to be paralleled by lower incidence of nasopharyngeal diseases. This incidence amounted in pupils with overweight to 4.1% of cases, and in the remaining ones to 2.0-2.3%. Nasopharyngeal diseases were recorded in 5.4-5.5% of pupils complaining of poor general feeling (headache, sleep disturbances), and in as many as 7.0% of those experiencing difficulties in falling asleep. As concerns the progress in learning, the difficulties between better and worse pupils in the incidence of nasopharyngeal diseases were insignificant. These diseases occurred somewhat more frequently in pupils with up to 14 days of justified non-attendance per semester, as compared with those without any non-attendance or with non-attendance lasting more than 14 days. AU - Ignar-Golinowska, B. AU - Roszkowska, H. DA - 1991 DP - PubMed IS - 1 J2 - Rocz Panstw Zakl Hig KW - Adolescent Age Factors Chronic Disease Educational Measurement Female Humans Learning Life Style Male Nasopharyngeal Diseases Poland Socioeconomic Factors Students LA - pol PY - 1991 SN - 0035-7715 SP - 91-99 ST - Effect of chronic nasopharyngeal diseases among 14-year-old students and extra-curricular factors on school performance T2 - Roczniki Panstwowego Zakladu Higieny TI - Effect of chronic nasopharyngeal diseases among 14-year-old students and extra-curricular factors on school performance UR - http://www.ncbi.nlm.nih.gov/pubmed/1788518 VL - 42 ID - 5 ER - TY - JOUR AB - BACKGROUND: Children with advanced cancer experience high symptom distress, which negatively impacts their health-related quality of life (HRQOL). To the authors' knowledge, the relationship between income and symptom distress and HRQOL is not well described. METHODS: The Pediatric Quality of Life and Symptoms Technology (PediQUEST) multisite clinical trial evaluated an electronic patient-reported outcome system to describe symptom distress and HRQOL in children with advanced cancer via repeated surveys. The authors performed a secondary analysis of PediQUEST data for those children with available parent-reported household income (dichotomized at 200% of the Federal Poverty Level and categorized as low income [<$50,000/year] or high income [≥$50,000/year]). The prevalence of the 5 most commonly reported physical and psychological symptoms was compared between groups. Multivariable generalized estimating equation models were used to test the association between household income and symptom distress and HRQOL. RESULTS: A total of 78 children were included in the analyses: 56 (72%) in the high-income group and 22 (28%) in the low-income group. Low-income children were more likely to report pain than high-income children (64% vs 42%; P=.02). In multivariable models, children from low-income families demonstrated a uniform trend toward higher total (β(low-high) =3.1; 95% confidence interval [95% CI], -0.08 to 6.2 [P=.06]), physical (β=3.8; 95% CI, -0.4 to 8.0 [P=.09]), and psychological (β=3.46; 95% CI, -1.91 to 8.84 [P=.21]) symptom distress compared with children from high-income families. Low income was associated with a uniform trend toward lower total (β=-7.9; 95% CI, -14.8, to -1.1 [P=.03]), physical (β=-11.2; 95% CI, -21.2 to -1.2 [P=.04]), emotional (β=-5.8; 95% CI, -13.6 to 2.0 [P=.15]), social (β=-2.52; 95% CI, -9.27 to 4.24 [P=.47]), and school (β=-9.8; 95% CI, -17.8 to -1.8 [P=.03]) HRQOL. CONCLUSIONS: In this cohort of children with advanced cancer, children from low-income families were found to experience higher symptom burden and worse QOL. AD - Department of Pediatric Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts. Harvard Medical School, Boston, Massachusetts. Division of Population Sciences' Center for Outcomes and Policy Research, Dana-Farber Cancer Institute, Boston, Massachusetts. Center for Research and Implementation in Palliative Care, Institute for Clinical Effectiveness and Health Policy, Buenos Aires, Argentina. Seattle Children's Hospital Cancer and Blood Disorders Center, Seattle, Washington. Department of Pediatrics, University of Washington, Seattle, Washington. Treuman Katz Center for Pediatric Bioethics, Seattle Children's Research Institute, Seattle, Washington. The Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. Section of Palliative Care, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas. AN - 30216416 AU - Ilowite, M. F. AU - Al-Sayegh, H. AU - Ma, C. AU - Dussel, V. AU - Rosenberg, A. R. AU - Feudtner, C. AU - Kang, T. I. AU - Wolfe, J. AU - Bona, K. C2 - PMC6561342 C6 - NIHMS1033764 DA - Oct 1 DO - 10.1002/cncr.31668 DP - NLM ET - 2018/09/15 IS - 19 KW - Adolescent Cancer Pain/complications/economics/epidemiology Child Child, Preschool Cost of Illness Disease Progression Family Characteristics Female Health Status Disparities Humans Income/*statistics & numerical data Male Neoplasms/complications/economics/*epidemiology/pathology Patient Reported Outcome Measures Poverty/psychology/statistics & numerical data Prevalence *Quality of Life/psychology Self Report/*statistics & numerical data Social Class Stress, Psychological/complications/economics/*epidemiology Surveys and Questionnaires *Pediatric Quality of Life and Symptoms Technology (PediQUEST) *disparity in symptom burden *patient-reported outcomes *pediatric advanced cancer *pediatric palliative care LA - eng N1 - 1097-0142 Ilowite, Maya F Al-Sayegh, Hasan Ma, Clement Dussel, Veronica Rosenberg, Abby R Feudtner, Chris Kang, Tammy I Wolfe, Joanne Bona, Kira K07 CA096746/CA/NCI NIH HHS/United States K07 CA211847/CA/NCI NIH HHS/United States Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Cancer. 2018 Oct 1;124(19):3934-3941. doi: 10.1002/cncr.31668. Epub 2018 Sep 14. PY - 2018 SN - 0008-543X (Print) 0008-543x SP - 3934-3941 ST - The relationship between household income and patient-reported symptom distress and quality of life in children with advanced cancer: A report from the PediQUEST study T2 - Cancer TI - The relationship between household income and patient-reported symptom distress and quality of life in children with advanced cancer: A report from the PediQUEST study VL - 124 ID - 3106 ER - TY - JOUR AB - Objective: To explore association between medically unexplained symptoms in children in Pakistan with emotional difficulties and functional impairments. Methods: We conducted a matched three-group case-control study of 186 children aged 8-16 years in Lahore, Pakistan. Cases were 62 children with chronic somatic symptoms for which no organic cause was identified after investigations. Two control groups of 62 children with chronic medical paediatric conditions, and 62 healthy children were identified. Cases and controls were matched for gender, age, and school class. Somatisation was measured with the Children's Somatisation Inventory (CSI-24) while anxiety and depression were measured with the Spencer Children's Anxiety Scale and the Short Mood and Feelings Questionnaire respectively. All questionnaires were translated into Urdu. Results: Mean age was 11.7 years (SD = 2.1). Cases scored significantly higher on somatisation (CSI-24), anxiety and depression than both control groups. Paediatric controls scored significantly higher than healthy controls on all three measures. Two hierarchical linear regression models were used to explore if somatisation predicted depression and anxiety while controlling for several confounders. Somatisation (higher CSI-24 scores) independently and significantly predicted higher anxiety (beta = .37, p = .0001) and depression (beta = .41, p = .0001) scores. Conclusion: This is the first study to show an association between medically unexplained symptoms and anxiety and depression in Pakistani children. This highlights the importance of screening for emotional difficulties in children presenting with unexplained somatic symptoms in this region. (C) 2013 Elsevier Inc. All rights reserved. AN - WOS:000331597700004 AU - Imran, N. AU - Ani, C. AU - Mahmood, Z. AU - Hassan, K. A. AU - Bhatti, M. R. DA - Feb DO - 10.1016/j.jpsychores.2013.11.016 IS - 2 N1 - Imran, Nazish Ani, Cornelius Mahmood, Zahid Hassan, Khawaja Amjad Bhatti, Muhammad Riaz 1879-1360 PY - 2014 SN - 0022-3999 SP - 105-112 ST - Anxiety and depression predicted by medically unexplained symptoms in Pakistani children: A case-control study T2 - Journal of Psychosomatic Research TI - Anxiety and depression predicted by medically unexplained symptoms in Pakistani children: A case-control study UR - ://WOS:000331597700004 VL - 76 ID - 2322 ER - TY - JOUR AB - Background/Aims: Constipation and headache are prevalent conditions among children worldwide. Previous studies have shown the relationship between upper gastrointestinal complaints and headache in children. However, the association with lower gastrointestinal complaints such as constipation has not been investigated until present. The aim of this study is to evaluate the relationship between headache and chronic functional constipation in children aged 4-12 years old. Materials and Methods: This cross-sectional study has evaluated the prevalence of headache in 326 children in Shiraz, Iran 2012. All the subjects and their parents were interviewed based on a structured questionnaire for the diagnosis of constipation and headache. Children with constipation were selected from the Pediatric Gastroenterology Clinic Affiliated to the Shiraz University of Medical Sciences. The control group was selected from healthy children attending Shiraz schools. Diagnosis of headache and constipation were made based on the second Edition of The International Headache Classification (ICHD-2) and ROME III criteria, respectively. Results: Headache prevalence among children with constipation was significantly higher (19.8%) than that of the control group (5.6%) [Odds ratio (OR) 4.192, p<0.001], which was significant only in the non-migraine headache subtypes (15.1% vs 2.8%, OR 25, p<0.002). Among the headache subtypes of different severity (mild, moderate, severe), only mild headache was significantly more prevalent in constipated children (14.9% vs. 1.4%, in the control group, respectively, p<0.001). Conclusion: This study revealed a strong correlation between headache and chronic functional constipation, which can result from the effect of these comorbid conditions with emotional stress, depression, and anxiety. AN - WOS:000345023700006 AU - Inaloo, S. AU - Dehghani, S. M. AU - Hashemi, S. M. AU - Heydari, M. AU - Heydari, S. T. DA - Oct DO - 10.5152/tjg.2014.6183 IS - 5 N1 - Inaloo, Soror Dehghani, Seyyed Mohsen Hashemi, Seyyed Mohammad Heydari, Mojtaba Heydari, Seyyed Taghi Heydari, Mojtaba/V-7630-2019; inaloo, soroor/T-7292-2018; Heydari, Seyyed Taghi/AAI-9180-2021; Heydari, Seyed Taghi/U-9403-2019; Heydari, Mojtaba/H-9224-2013; Dehghani, Seyed Mohsen/A-9226-2018 inaloo, soroor/0000-0002-5621-3473; Heydari, Seyyed Taghi/0000-0001-7711-1137; Heydari, Mojtaba/0000-0001-9612-0936; Dehghani, Seyed Mohsen/0000-0001-5930-0110 2148-5607 PY - 2014 SN - 1300-4948 SP - 508-511 ST - Comorbidity of headache and functional constipation in children: A cross-sectional survey T2 - Turkish Journal of Gastroenterology TI - Comorbidity of headache and functional constipation in children: A cross-sectional survey UR - ://WOS:000345023700006 VL - 25 ID - 2286 ER - TY - JOUR AB - BACKGROUND AND PURPOSE: CACNA1A encodes the α1 subunit of the neuronal calcium channel P/Q. CACNA1A mutations underlie three allelic disorders: familial hemiplegic migraine type 1 (FHM1), episodic ataxia type 2 (EA2) and spinocerebellar ataxia type 6 (SCA6). A clear-cut genotype-phenotype correlation is often lacking since clinical manifestations may overlap. Several case reports have described cognitive and behavioral features in CACNA1A disorders, but studies in larger case series are lacking. METHODS: Genetically confirmed CACNA1A cases were retrieved from the database of the ataxia outpatient clinic of the Department of Neurology at Innsbruck Medical University. Clinical charts and neuropsychological test results were retrospectively analyzed. In addition, a review of the literature including only genetically confirmed cases was performed. RESULTS: Forty-four CACNA1A cases were identified in our database. Delayed psychomotor milestones and poor school performance were described in seven (four FHM1, three EA2) and eight (three FHM1, five EA2) patients, respectively. Psychiatric comorbidities were diagnosed in eight patients (two FHM1, six EA2). Neuropsychological testing was available for 23 patients (11 FHM1, 10 EA2, two SCA6). Various cognitive deficits were documented in 21 cases (all patients except one SCA6). Impairments were predominantly seen in figural memory, visuoconstructive abilities and verbal fluency. In the literature, an early psychomotor delay is described in several children with EA2 and FHM1, whilst reports of cognitive and psychiatric findings from adult cases are scarce. CONCLUSIONS: Neuropsychiatric manifestations are common in episodic CACNA1A disorders. In the case of otherwise unexplained developmental delay and a positive family history, CACNA1A mutations should be considered in the differential diagnosis. AD - Department of Neurology, Innsbruck Medical University, Innsbruck, Austria. Department of Neuroradiology, Innsbruck Medical University, Innsbruck, Austria. AN - 30063100 AU - Indelicato, E. AU - Nachbauer, W. AU - Karner, E. AU - Eigentler, A. AU - Wagner, M. AU - Unterberger, I. AU - Poewe, W. AU - Delazer, M. AU - Boesch, S. DA - Jan DO - 10.1111/ene.13765 DP - NLM ET - 2018/08/01 IS - 1 KW - Adolescent Adult Ataxia/genetics Calcium Channels/*genetics Cerebellar Ataxia/genetics Child Child, Preschool Comorbidity Educational Status Female Genotype Humans Male Mental Disorders/*genetics/psychology Migraine Disorders/genetics Nervous System Diseases/*genetics/psychology Neuropsychological Tests Phenotype Psychomotor Performance Retrospective Studies Spinocerebellar Ataxias/genetics Young Adult * cacna1a *developmental delay *episodic ataxia type 2 *familial hemiplegic migraine type 1 *neuropsychological testing LA - eng N1 - 1468-1331 Indelicato, E Orcid: 0000-0003-0217-8630 Nachbauer, W Karner, E Eigentler, A Wagner, M Unterberger, I Poewe, W Delazer, M Boesch, S Journal Article Research Support, Non-U.S. Gov't England Eur J Neurol. 2019 Jan;26(1):66-e7. doi: 10.1111/ene.13765. Epub 2018 Sep 3. PY - 2019 SN - 1351-5101 SP - 66-e7 ST - The neuropsychiatric phenotype in CACNA1A mutations: a retrospective single center study and review of the literature T2 - Eur J Neurol TI - The neuropsychiatric phenotype in CACNA1A mutations: a retrospective single center study and review of the literature VL - 26 ID - 3796 ER - TY - JOUR AB - Temporomandibular joint (TMJ) may be involved in different JIA subtypes, with a prevalence ranging between 40 to 70%, leading to various degrees of disability, mainly related to pain, inflammation, reduced mandibular mobility, damage of the condyle and secondary masticatory muscle impairment. The aim of the present work was to describe TMJ involvement in different subtypes of JIA, based on a complex epidemiological, clinical and imaging approach. We performed a prospective observational study on 22 consecutive JIA attending an academic rheumatology department. Imagistic assessments comprised: (i) an X-ray of vertebral (lumbar and cervical spine) as well as peripheral joints in order to support the diagnosis and to evaluate the stage of the disease; (ii) a TMJ ultrasonography; (iii) a TMJ CT scan; and (iv) a CBCT. The following parameters were evaluated in our patients: demographics and general characteristics (sex, age, duration of disease, JIA onset); TMJ-related data e.g. spontaneous or provoked unilateral or bilateral TMJ pain measured on a visual analog scale (VAS), accompanied by morning stiffness or stiffness after rest; clicking and crepitation were noted in the context mandible mobilization; muscle contracture (masseter, temporal, internal pterygoid); parafunctions; TMJ imaging; dental, gingival and occlusal status. TMJ involvement is classically described among JIA patients, presenting with various clinical signs and symptoms and different degrees of inflammation and condylar damage. AN - WOS:000407691600010 AU - Iordache, C. AU - Fatu, A. M. AU - Pomarleanu, C. AU - Scurtu, D. AU - Ancuta, C. DA - Jan-Mar IS - 1 N1 - Iordache, Cristina Fatu, Ana Maria Pomarleanu, Cristina Scurtu, Daniel Ancuta, Codrina Ancuta, codrina/aam-1079-2020 Ancuta, codrina/0000-0002-1777-8121 PY - 2017 SN - 2066-7000 SP - 60-67 ST - TEMPOROMANDIBULAR JOINT IN JUVENILE IDIOPATHIC ARTRITIS: AN IMAGING STUDY AND ERGONOMIC CONSIDERATIONS T2 - Romanian Journal of Oral Rehabilitation TI - TEMPOROMANDIBULAR JOINT IN JUVENILE IDIOPATHIC ARTRITIS: AN IMAGING STUDY AND ERGONOMIC CONSIDERATIONS UR - ://WOS:000407691600010 VL - 9 ID - 2119 ER - TY - JOUR AB - P>Visceral hypersensitivity is often considered to play a major etiologic role in the pathophysiology of irritable bowel syndrome in adults, and some authors argue that this increased sensitivity is mainly due to psychological factors. In contrast, there are no data in children with irritable bowel syndrome which confirm this relationship. The aim of the study was to evaluate the relationship between psychosocial aspects and sensorymotor function in children affected by irritable bowel syndrome. Ten children fulfilling the Rome II criteria for irritable bowel syndrome and seven healthy controls were enrolled. We studied the thresholds and the perception of visceral stimuli in the rectum by means of an electronic barostat (isobaric phasic distentions, 3 mmHg/1 min, interval 1 min) and a validated questionnaire. Personality features were evaluated by means of the Big Five Questionnaire for Children. Sleep, mood disturbance, anxiety and individual performance (missed school days, school results and social activities) were also evaluated. Children with irritable bowel syndrome showed significantly lower thresholds for discomfort (14.8 +/- 3.5 vs 22.3 +/- 6.9 mmHg, P = 0.010) and a higher cumulative perception score (28.2 +/- 11.1 vs 12.3 +/- 8.0, P = 0.005) compared with healthy controls. A higher emotional instability (57.8 +/- 7.0 vs 48.7 +/- 10.1, P = 0.047), sleep disturbance (7.2 +/- 1.0 vs 9.3 +/- 0.5, P = 0.004) and anxiety (6.3 +/- 2.0 vs 2.3 +/- 1.7, P = 0.009) were observed in irritable bowel syndrome patients. Moreover, in a multivariate analysis, the cumulative perception score was significantly related to emotional instability (P = 0.042). In conclusion children with irritable bowel syndrome exhibit visceral hypersensitivity and psychosocial impairment. Emotional instability, as a personality feature in these children, seems to modulate the perception response to visceral stimulations. AN - WOS:000268710600007 AU - Iovino, P. AU - Tremolaterra, F. AU - Boccia, G. AU - Miele, E. AU - Ruju, F. M. AU - Staiano, A. DA - Sep DO - 10.1111/j.1365-2982.2009.01303.x IS - 9 N1 - Iovino, P. Tremolaterra, F. Boccia, G. Miele, E. Ruju, F. M. Staiano, A. IOVINO, PAOLA/G-6195-2011; Staiano, Annamaria/H-3026-2011; Miele, Erasmo/A-1906-2010 IOVINO, PAOLA/0000-0002-9568-0680; Staiano, Annamaria/0000-0003-0586-1339; PY - 2009 SN - 1350-1925 ST - Irritable bowel syndrome in childhood: visceral hypersensitivity and psychosocial aspects T2 - Neurogastroenterology and Motility TI - Irritable bowel syndrome in childhood: visceral hypersensitivity and psychosocial aspects UR - ://WOS:000268710600007 VL - 21 ID - 2592 ER - TY - JOUR AB - BACKGROUND: Headache is the most common pain disorder in children and adolescents and is associated with diverse dysfunctions and psychological symptoms. Several studies evidenced sex-specific differences in headache frequency. Until now no study exists that examined sex-specific patterns of change in paediatric headache across time and included pain-related somatic and (socio-)psychological predictors. METHOD: Latent Class Growth Analysis (LCGA) was used in order to identify different trajectory classes of headache across four annual time points in a population-based sample (n = 3 227; mean age 11.34 years; 51.2 % girls). In multinomial logistic regression analyses the influence of several predictors on the class membership was examined. RESULTS: For girls, a four-class model was identified as the best fitting model. While the majority of girls reported no (30.5 %) or moderate headache frequencies (32.5 %) across time, one class with a high level of headache days (20.8 %) and a class with an increasing headache frequency across time (16.2 %) were identified. For boys a two class model with a 'no headache class' (48.6 %) and 'moderate headache class' (51.4 %) showed the best model fit. Regarding logistic regression analyses, migraine and parental headache proved to be stable predictors across sexes. Depression/anxiety was a significant predictor for all pain classes in girls. Life events, dysfunctional stress coping and school burden were also able to differentiate at least between some classes in both sexes. CONCLUSIONS: The identified trajectories reflect sex-specific differences in paediatric headache, as seen in the number and type of classes extracted. The documented risk factors can deliver ideas for preventive actions and considerations for treatment programmes. AD - Georg-Elias-Müller-Institute of Psychology, Department of Clinical Psychology and Psychotherapy, University of Göttingen, Gosslerstraße 14, 37073, Göttingen, Germany. corinna.isensee@psych.uni-goettingen.de. Department of Child and Adolescent Psychiatry and Psychotherapy, University Medical Center of Göttingen, Göttingen, Germany. corinna.isensee@psych.uni-goettingen.de. Georg-Elias-Müller-Institute of Psychology, Department of Clinical Psychology and Psychotherapy, University of Göttingen, Gosslerstraße 14, 37073, Göttingen, Germany. AN - 27076175 AU - Isensee, C. AU - Fernandez Castelao, C. AU - Kröner-Herwig, B. C2 - PMC4830779 DO - 10.1186/s10194-016-0627-8 DP - NLM ET - 2016/04/15 KW - Adolescent Anxiety/*psychology Child Depression/*psychology Disease Progression Female Headache/*diagnosis/psychology Humans Male *Models, Theoretical Risk Factors Sex Factors Developmental trajectories Lcga Paediatric headache Sex-specific analyses LA - eng N1 - 1129-2377 Isensee, Corinna Fernandez Castelao, Carolin Kröner-Herwig, Birgit Journal Article Research Support, Non-U.S. Gov't J Headache Pain. 2016;17:32. doi: 10.1186/s10194-016-0627-8. Epub 2016 Apr 14. PY - 2016 SN - 1129-2369 (Print) 1129-2369 SP - 32 ST - Developmental trajectories of paediatric headache - sex-specific analyses and predictors T2 - J Headache Pain TI - Developmental trajectories of paediatric headache - sex-specific analyses and predictors VL - 17 ID - 3850 ER - TY - JOUR AB - Background: Headache is a common symptom with a high prevalence in most epidemiological studies. It is one of the 10 most common reasons for outpatient physician visits. Headaches are common in children and the prevalence increases with increasing age. The aim of the study: was to find out the prevalence of headache among school age children and study different attributes associated with headaches in Ain Helwan district. Method: Descriptive research design was carried out at primary, preparatory and secondary public schools in Ain Helwan district. Subjects: included 378 school age children 10-17 years, from both gender. Sample: A simple random sample was recruited, utilizing the non-probability sampling technique. Tool: The researchers utilized self-administered interview sheet to collect data in relation to personal information of the studied sample, their eating habits, and life style pattern. Data were collected in the period from beginning of March 2011 till the end of April 2011. Results: revealed that, out of 378, students 221 were complaining from headache (58.5%). No statistically significant differences were detected between middle childhood and late childhood students regarding dizziness during car riding, sensitivity to certain smile, extreme noise, in addition to intensity of headache that increases with climbing stairs, sport, cough, change body posture, activity, teeth or gums' pain, ear problems, nervousness, vision problems and taking vitamins or drugs. Less than three quarters of sample had inadequate or irregular sleep (72.4%) and there were highly statistically significant differences between middle childhood and late childhood students regarding inadequate or irregular sleep and eating chocolate or cheese, skipping meals, drinking caffeine, staying long time in front of TV or computer, ingestion of cold drink or ice cream, smoking, and complying of any unhealthy condition. More than three quarters of the studied sample showed clinical manifestations of headache in stabbing pain followed by pressing headache (83.7% & 77.8 % respectively). Results revealed adverse effects of headache through scholastic achievement, school attendance and daily activity with no significant differences. Conclusion: Headache represents a common disabling health problem among school age children in Ain Helwan district with a prevalence rate of 58.4%. In general, the prevalence of headache increases with age and it is higher in males than females. Stress following staying long time in front of TV or computer was the most common precipitating factor for headache in the study. Recommendation: Health education of the parents and children about the precipitating factors which triggers for headache, and increasing awareness about healthy life style, and early diagnosis and treatment of headache are recommended to avoid its drawbacks on child health and school performance. [Safaa Salah Ismail and Afaf Salah Abed El-Mohsen Headache in School Age Children and Its Possible Related Expected Predisposing Factors: An Assessment Study] Life Science Journal 2012; 9(1):617-627]. (ISSN: 1097-8135). http://www.lifesciencesite.com. 91 AN - WOS:000306398400091 AU - Ismail, S. S. AU - El-Mohsen, A. S. A. IS - 1 N1 - Ismail, Safaa Salah El-Mohsen, Afaf Salah Abed PY - 2012 SN - 1097-8135 SP - 617-627 ST - Headache in School Age Children and Its Possible Related Expected Predisposing Factors: An Assessment Study T2 - Life Science Journal-Acta Zhengzhou University Overseas Edition TI - Headache in School Age Children and Its Possible Related Expected Predisposing Factors: An Assessment Study UR - ://WOS:000306398400091 VL - 9 ID - 2459 ER - TY - JOUR AB - Children who are chronically complaining nonspecific symptoms such as headache, fatigue, abdominal pain, and low grade fever are commonly seen in daily pediatric outpatient clinics. Some of them are unable to go to school and are diagnosed as school refusal by physicians or educational staff. On the other hand, there are children who do not fulfill any criteria of collagen diseases and whose anti-nuclear antibodies (ANA) are found to be positive. Some of these children have chronic nonspecific complaints. We prospectively studied the prevalence of ANA in children who visited a pediatric outpatient clinic because of chronic nonspecific complaints. Surprisingly, 74 out of 140 symptomatic children (52.4%) were positive for ANA, while only 5 out of 82 healthy control children (6.1%) were positive (p < 0.0001). 39 of 74 ANA positive patients (52.1%) have low ANA titers less than or equal to 1:80, nevertheless 36 patients (47.9%) have high ANA titers greater than or equal to 1:160. ANA fluorescent patterns were homogeneous and speckled in 75.3%, speckled in 17.6% and others in 6.8%. ANA positive patients tended to have general fatigue and low grade fever, while gastrointestinal problems such as abdominal pain and diarrhea and orthostatic dysregulation symptoms were commonly seen in ANA negative patients. Children who were unable to go to school more than 1 day a week were seen significantly more in ANA positive patients than in negative patients. Autoantibody analysis using Western immunoblot revealed that 26 out of 63 ANA positive sera (41.3%) had antibodies to the 62 kD protein which had not been previously noticed. These data suggest that autoimmune mechanism may play a role in childhood chronic nonspecific symptoms. We therefore propose a new disease entity of the autoimmune fatigue syndrome in children. When chronically complaining children visit a pediatric out-patient clinic, immunological approaches should be considered before they are discriminated as school refusal or having psychogenic disorders. AN - WOS:A1997XZ29500006 AU - Itoh, Y. AU - Hamada, H. AU - Imai, T. AU - Seki, T. AU - Igarashi, T. AU - Yuge, K. AU - Fukunaga, Y. AU - Yamamoto, M. DO - 10.3109/08916939708994733 IS - 4 N1 - Itoh, Y Hamada, H Imai, T Seki, T Igarashi, T Yuge, K Fukunaga, Y Yamamoto, M Itoh, Yasuhiko/0000-0002-4999-6473 PY - 1997 SN - 0891-6934 SP - 243-250 ST - Antinuclear antibodies in children with chronic nonspecific complaints T2 - Autoimmunity TI - Antinuclear antibodies in children with chronic nonspecific complaints UR - ://WOS:A1997XZ29500006 VL - 25 ID - 2914 ER - TY - JOUR AB - Background: The purpose of this study was to determine if earlier age of first exposure to football is associated with worse brain health in middle-aged and older adult men who played high school football. Methods: Men from the United States, aged 35 and older, who reported playing high school football, completed a customized, online health survey via the Amazon Mechanical Turk (mTurk) platform. Survey items included physical, psychological, and cognitive symptoms over the past week and over the past year, sports participation history (including age of first exposure to football), medical history, and concussion history. Participants also completed the Patient Health Questionnaire-8 (PHQ-8) and the British Columbia Post-Concussion Symptom Inventory (BC-PSI). Results: There were 186 men (age M = 51.78, SD = 10.93) who participated in high school football, and 87 (46.8%) reported football participation starting before the age of 12 and 99 (53.2%) reported football participation at or after the age of 12. Those who started playing football at an earlier age reported a greater number of lifetime concussions (M = 1.95, SD = 1.79) compared to those who started playing at age 12 or later (M = 1.28, SD = 1.52; U = 3,257.5, p = 0.003). A similar proportion of men who played football before vs. after the age of 12 reported a lifetime history of being prescribed medications for depression, anxiety, chronic pain, headaches, or memory problems. When comparing men who played football before vs. after the age of 12, the groups did not differ significantly in their ratings of depression, anger, anxiety, headaches, migraines, neck or back pain, chronic pain, concentration problems, or memory problems over the past week or the past year. The two groups did not differ significantly in their ratings of current symptoms of depression (PHQ-8; U = 4,187.0, p = 0.74) or post-concussion-like symptoms (BC-PSI; U = 3,944.0, p = 0.53). Furthermore, there were no statistically significant correlations between the age of first exposure to football, as a continuous variable, and PHQ-8 or BC-PSI scores. Conclusion: This study adds to a rapidly growing body of literature suggesting that earlier age of first exposure to football is not associated with later-in-life brain health. AD - Department of Physical Medicine and Rehabilitation, Harvard Medical School, Boston, MA, United States. Spaulding Research Institute, Spaulding Rehabilitation Hospital, Charlestown, MA, United States. Sports Concussion Program, MassGeneral Hospital for Children, Boston, MA, United States. Home Base, A Red Sox Foundation and Massachusetts General Hospital Program, Charlestown, MA, United States. School of Health and Rehabilitation Sciences, The Ohio State University College of Medicine, Columbus, OH, United States. Department of Physical Medicine and Rehabilitation, University of North Carolina, UNC Memorial Hospital, Chapel Hill, NC, United States. LeBauer Department of Neurology, Moses H. Cone Memorial Hospital, Greensboro, NC, United States. Physiotherapy and Sports Science, School of Public Health, University College Dublin, Dublin, Ireland. AN - 34025554 AU - Iverson, G. L. AU - Caccese, J. B. AU - Merz, Z. C. AU - Büttner, F. AU - Terry, D. P. C2 - PMC8131846 DO - 10.3389/fneur.2021.647314 DP - NLM ET - 2021/05/25 KW - chronic traumatic encephalopathy concussion head trauma subconcussive traumatic brain injury Operations, LLC, and Highmark, Inc. He has a clinical and consulting practice in forensic neuropsychology, including expert testimony, involving individuals who have sustained mild TBIs (including athletes). He has received research funding from several test publishing companies, including ImPACT Applications, Inc., CNS Vital Signs, and Psychological Assessment Resources (PAR, Inc.). He has received research funding as a principal investigator from the National Football League, and subcontract grant funding as a collaborator from the Harvard Integrated Program to Protect and Improve the Health of National Football League Players Association Members. DT is a consultant for REACT Neuro, Inc. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. LA - eng N1 - 1664-2295 Iverson, Grant L Caccese, Jaclyn B Merz, Zachary C Büttner, Fionn Terry, Douglas P Journal Article Front Neurol. 2021 May 5;12:647314. doi: 10.3389/fneur.2021.647314. eCollection 2021. PY - 2021 SN - 1664-2295 (Print) 1664-2295 SP - 647314 ST - Age of First Exposure to Football Is Not Associated With Later-in-Life Cognitive or Mental Health Problems T2 - Front Neurol TI - Age of First Exposure to Football Is Not Associated With Later-in-Life Cognitive or Mental Health Problems VL - 12 ID - 4129 ER - TY - JOUR AB - The purpose of this study was to determine if earlier age of first exposure (AFE) to football is associated with worse brain health in middle-aged men who played high school football. We assessed 123 men 35-55 years of age, who played high school football, using (1) a survey of demographic information as well as medical, sport participation, and concussion history; (2) the Patient Health Questionnaire-8 (PHQ-8); and (3) the British Columbia Post-Concussion Symptom Inventory (BC-PSI). Sixty-two (50.4%) men reported football participation starting before the age of 12 (i.e., AFE <12 years) and 61 (49.6%) reported football participation at or after the age of 12 (AFE > 12 years). Compared with those with AFE >12 years, a similar proportion of former high school football players who began playing tackle football before age 12 reported that they had been prescribed medications for mental health problems or that they had recently experienced symptoms of anxiety, depression, memory loss, chronic pain, or headaches. Moreover, there was no significant difference in their lifetime history of treatment by a mental health professional. The groups did not differ significantly on PHQ-8 (U = 1839.0, p = 0.791) or BC-PSI total scores (U = 1828.5, p = 0.751). These findings suggest that earlier AFE to football is not associated with worse brain health in middle-aged men in this sample who played high school football. AD - Department of Physical Medicine and Rehabilitation, Harvard Medical School, Boston, Massachusetts, USA. Spaulding Rehabilitation Hospital, Charlestown, Massachusetts, USA. Spaulding Research Institute, Charlestown, Massachusetts, USA. MassGeneral Hospital for Children Sports Concussion Program, Boston, Massachusetts, USA. Home Base, A Red Sox Foundation and Massachusetts General Hospital Program, Charlestown, Massachusetts, USA. Center for Health and Rehabilitation Research, Charlestown, Massachusetts, USA. School of Health and Rehabilitation Sciences, The Ohio State University College of Medicine, Columbus, Ohio, USA. School of Public Health, Physiotherapy and Sports Science, University College Dublin, Dublin, Ireland. Department of Physical Medicine and Rehabilitation, University of North Carolina at Chapel Hill, UNC Memorial Hospital, Chapel Hill, North Carolina. AN - 33126834 AU - Iverson, G. L. AU - Terry, D. P. AU - Caccese, J. B. AU - Büttner, F. AU - Merz, Z. C. DA - Mar DO - 10.1089/neu.2020.7041 DP - NLM ET - 2020/11/01 IS - 5 KW - age behavior cognitive function concussion head trauma traumatic brain injury LA - eng N1 - 1557-9042 Iverson, Grant L Terry, Douglas P Caccese, Jaclyn B Büttner, Fionn Merz, Zachary C Journal Article United States J Neurotrauma. 2021 Mar;38(5):538-545. doi: 10.1089/neu.2020.7041. Epub 2020 Dec 11. PY - 2021 SN - 0897-7151 SP - 538-545 ST - Age of First Exposure to Football Is Not Associated with Midlife Brain Health Problems T2 - J Neurotrauma TI - Age of First Exposure to Football Is Not Associated with Midlife Brain Health Problems VL - 38 ID - 4183 ER - TY - JOUR AB - The paper discusses the prevalence, pattern, and risk factors of childhood headache (HA) according to questionnaire data from 1074 general educational school pupils. Periodic HA was reported by 42.1% of the children. There was a preponderance of exercise-induced HA (30.6%) and migraine (7.8%). There was an age and gender determination of childhood HA frequency; there was a predominance of chronic exercise-induced HA, migraine, and their concomitant forms in female adolescents. There was a high comorbidity of primary HA with other psychosomatic disorders mainly with autonomic dysfunction and emotional disorders. The risk factors for chronic HA were a poor family history (familial psychogenias, pain family history, low'socioeconomic status family), and school stress. The clinical form of cephalgia, comorbidities, and predictive factors should be taken into account to prevent and treat HA. The use of the international diagnostic criteria developed by the experts of the HA Association is of cardinal importance in improving the diagnosis of childhood HA. AN - 22250391 AU - Izmaĭlova, I. G. AU - Belopasov, V. V. AU - Korol'kova, V. S. AU - Shvarts, M. N. DA - Nov-Dec DP - NLM ET - 2012/01/19 IS - 6 KW - Adolescent Child Chronic Disease Female *Headache/epidemiology/etiology/psychology Humans Male Migraine Disorders/epidemiology/etiology/psychology Prevalence Risk Factors Russia Socioeconomic Factors Students/*psychology/statistics & numerical data Surveys and Questionnaires Tension-Type Headache/epidemiology/etiology/psychology LA - rus N1 - Izmaĭlova, I G Belopasov, V V Korol'kova, V S Shvarts, M N English Abstract Journal Article Russia (Federation) Gig Sanit. 2011 Nov-Dec;(6):44-7. PY - 2011 SN - 0016-9900 (Print) 0016-9900 SP - 44-7 ST - [Headache in the population of schoolchildren: prevalence, pattern, risk factors] T2 - Gig Sanit TI - [Headache in the population of schoolchildren: prevalence, pattern, risk factors] ID - 3321 ER - TY - JOUR AB - Introduction: Hereditary fructose intolerance is a metabolic disease due to an aldolase B deficiency. Our objective was to ascertain the social and health care needs of those with this deficiency. Material and methods: A prospective, observational study was performed. A survey of social and health care needs was conducted to hereditary fructose intolerance patients living in Spain. Results: Most patients had been diagnosed, mainly by genetic analysis in children and based on fructose overload in adults. Population surveyed had no sequelae (72.34%) or disability (64%), and 83.33% of children and 52.38% of adults were taking drugs (p < .05) (2.06 drugs on average). Most patients had attended medical visits in the past two years, mainly in metabolic disease units (42.5%) and/or nutrition units (42.5%), but less than a half attended reference centers (mostly children [p < 0.05]). Although 48% were satisfied with health care, they felt discriminated in recreational activities, school, health and/or daily activities. The most reliable sources of information were the specialized care physician (69.39%) and patients' association (59.18%). Fifty-five percent reported no problem in any quality of life dimension, although some had problems in daily activities, pain, and anxiety. Conclusions: Although hereditary fructose intolerance is less disabling than other rare diseases, it is important to know the needs of those who suffer from it. Although time to diagnosis has shortened, the poorer health care and satisfaction with it perceived in adults makes it necessary to emphasize the needs of this population, and the critical need of training and information of health care professionals. (C) 2019 SEEN y SEQ. Published by Elsevier Espana, S.L.U. All rights reserved. AN - WOS:000523299100006 AU - Izquierdo-Garcia, E. AU - Escobar-Rodriguez, I. AU - Moreno-Villares, J. M. AU - Iglesias-Peinado, I. DA - Apr DO - 10.1016/j.endinu.2019.06.005 IS - 4 N1 - Izquierdo-Garcia, Elsa Escobar-Rodriguez, Ismael Manuel Moreno-Villares, Jose Iglesias-Peinado, Irene Izquierdo-Garcia, Elsa/0000-0002-2173-1027 PY - 2020 SN - 2530-0180 SP - 253-262 ST - Social and health care needs in patients with hereditary fructose intolerance in Spain T2 - Endocrinologia Diabetes Y Nutricion TI - Social and health care needs in patients with hereditary fructose intolerance in Spain UR - ://WOS:000523299100006 VL - 67 ID - 1832 ER - TY - JOUR AB - Background Despite evidence that intensive interdisciplinary pain treatment (IIPT) is effective in facilitating functional recovery in adolescents with chronic pain, engagement with IIPT is suboptimal among adolescents. A key aspect of IIPT is to support functional recovery via (re)engagement with age-appropriate daily activities. The aim of this study was to gain a comprehensive insight into adolescents' perceptions of the barriers they need to overcome to engage with age-appropriate activities in order to achieve functional recovery. Methods Forty-one adolescents who were starting an IIPT programme completed the 'passenger-on-the-bus metaphor', an exercise in which they identify and describe their perceived barriers (i.e. 'passengers' on their bus) that prevent them from engaging with age-appropriate activities. The responses were analysed using inductive thematic analyses to generate a taxonomy of perceived barriers to functional recovery. Results We generated a taxonomy of seven different barriers that participants described facing on their road to functional recovery: physical constraints, being 'fed up', low self-confidence and self-esteem, perfectionism, avoidance of engagement with pain, feelings (such as sadness, anger, guilt, anxiety) and social barriers (received from a range of sources such as parents, friends, school and wider society). Conclusion The findings reveal a variety of barriers that were perceived to hinder functional recovery through reduced engagement with age-appropriate activities and thereby hamper progress within IIPT. The Passenger on the bus metaphor can be used to identify similar barriers faced by adolescents in an individualized treatment approach, thereby making it possible for clinicians to target their IIPT more precisely. AN - WOS:000587345000001 AU - Jacobs, K. AU - Smith, A. AU - Heathcote, L. C. AU - Caes, L. DA - Feb DO - 10.1002/ejp.1673 IS - 2 N1 - Jacobs, Konrad Smith, Alisha Heathcote, Lauren C. Caes, Line 1532-2149 PY - 2021 SN - 1090-3801 SP - 348-358 ST - Which passengers are on your bus? A taxonomy of the barriers adolescents with chronic pain face in achieving functional recovery T2 - European Journal of Pain TI - Which passengers are on your bus? A taxonomy of the barriers adolescents with chronic pain face in achieving functional recovery UR - ://WOS:000587345000001 VL - 25 ID - 1786 ER - TY - JOUR AB - Objective: Earlier epidemiological studies have shown that headaches are frequent among adolescents, especially girls. In particular, recurrent primary headache disorders such as migraine and tension-type headaches are common complaints in this age group. Headaches are increasingly being recognized as a significant health problem in adolescents and can lead to significant disabilities by affecting their lives, their school performance and their social lives. The aim of this study was to compare the prevalence of primary headaches among adolescents aged 16-20 years in Norway in two periods. Very few replicate studies have re-evaluated the prevalence of primary headaches in this age range and it is uncertain whether the prevalence is increasing. Methods: Two cross-sectional, population-based studies were conducted in Norway from 1995 to 1997 (Young-HUNT 1) and from 1999 to 2001 (Young-HUNT 2). In Young-HUNT 1, 2594 adolescents in 2nd and 3rd grade in upper secondary school (aged 16-20 years) completed a comprehensive questionnaire including one question regarding headache during the last 12 months. In addition, 1730 of the students were interviewed about their headache complaints. In Young-HUNT 2, 2373 adolescents aged 16-20 years completed the same questionnaire and 1655 were interviewed in the same way as the earlier survey. The interviews were performed by trained nurses, and respondents were asked if they had experienced recurrent headache during the last year. If so, the headache was classified as migraine (MI), tension-type headache (TTH) or non-classifiable headache (NCH). Headache frequency during the past year was recorded according to the following categories: Less than 1 day per month (less than monthly), 1-3 days per month (monthly), 1-5 days per week (weekly), or more than 5 days per week (daily). Results: The participation rate was 88% in Young-HUNT 1 and 81% in Young-HUNT 2. The overall prevalence of having had headaches during the last 12 months did not change significantly (79.4% versus 77.5%; OR: 0.89, 95% CI: 0.79-1.02, p = 0.09), whereas the prevalence of recurrent headaches increased from 30.3% in Young-HUNT 1 to 35.4% in Young-HUNT 2 (OR: 1.26, 95% CI: 1.09-1.46, p = 0.002). The prevalence of tension-type headache changed significantly from 19.0% to 21.9% (OR: 1.20, 95% CI: 1.02-1.42, p = 0.03). Also the prevalence of migraine tended to increase (7.5% versus 8.7%, OR: 1.18, 95% CI: 0.92-1.52, p = 0.18). The overall frequency of recurrent headache changed towards more monthly and less weekly headache. Conclusions: This is the first large-scale population-based study among adolescents in Norway assessing changes in the prevalence of primary headaches over a four-year period of time. The overall prevalence of recurrent headaches increased significantly from Young-HUNT 1 to Young-HUNT 2. An increase was seen in all types of recurrent headaches and was significant for tension-type headache. Implications: Earlier follow-up studies have examined changes in prevalence of recurrent headaches in young age, but the results are diverging. Our findings support the impression that the prevalence of recurrent headache among adolescents is increasing, and underlines the need for prospective designed studies with emphasis on prognosis and etiological factors. (C) 2011 Scandinavian Association for the Study of Pain. Published by Elsevier B.V. All rights reserved. AN - WOS:000217895700012 AU - Jacobsen, B. A. AU - Dyb, G. AU - Hagen, K. AU - Stovner, L. J. AU - Holmen, T. L. AU - Zwart, J. A. DA - Jul DO - 10.1016/j.sjpain.2011.03.002 IS - 3 N1 - Jacobsen, Brit A. Dyb, Grete Hagen, Knut Stovner, Lars J. Holmen, Turid L. Zwart, John-Anker 1877-8879 PY - 2011 SN - 1877-8860 SP - 148-152 ST - The Nord-Trondelag Health Study shows increased prevalence of primary recurrent headaches among adolescents over a four-year period T2 - Scandinavian Journal of Pain TI - The Nord-Trondelag Health Study shows increased prevalence of primary recurrent headaches among adolescents over a four-year period UR - ://WOS:000217895700012 VL - 2 ID - 2488 ER - TY - JOUR AB - Objective Earlier epidemiological studies have shown that headaches are frequent among adolescents, especially girls. In particular, recurrent primary headache disorders such as migraine and tension-type headaches are common complaints in this age group. Headaches are increasingly being recognized as a significant health problem in adolescents and can lead to significant disabilities by affecting their lives, their school performance and their social lives. The aim of this study was to compare the prevalence of primary headaches among adolescents aged 16-20 years in Norway in two periods. Very few replicate studies have re-evaluated the prevalence of primary headaches in this age range and it is uncertain whether the prevalence is increasing. Methods Two cross-sectional, population-based studies were conducted in Norway from 1995 to 1997 (Young-HUNT 1) and from 1999 to 2001 (Young-HUNT 2). In Young-HUNT 1, 2594 adolescents in 2nd and 3rd grade in upper secondary school (aged 16-20 years) completed a comprehensive questionnaire including one question regarding headache during the last 12 months. In addition, 1730 of the students were interviewed about their headache complaints. In Young-HUNT 2, 2373 adolescents aged 16-20 years completed the same questionnaire and 1655 were interviewed in the same way as the earlier survey. The interviews were performed by trained nurses, and respondents were asked if they had experienced recurrent headache during the last year. If so, the headache was classified as migraine (MI), tensiontype headache (TTH) or non-classifiable headache (NCH). Headache frequency during the past year was recorded according to the following categories: Less than 1 day per month (less than monthly), 1-3 days per month (monthly), 1-5 days per week (weekly), or more than 5 days per week (daily). Results The participation rate was 88% in Young-HUNT 1 and 81% in Young-HUNT 2. The overall prevalence of having had headaches during the last 12 months did not change significantly (79.4% versus 77.5%; OR: 0.89, 95%CI: 0.79-1.02, p = 0.09), whereas the prevalence of recurrent headaches increased from 30.3% in Young-HUNT 1 to 35.4% in Young-HUNT 2 (OR: 1.26, 95%CI: 1.09-1.46, p = 0.002). The prevalence of tension-type headache changed significantly from 19.0% to 21.9% (OR: 1.20, 95%CI: 1.02-1.42, p = 0.03). Also the prevalence of migraine tended to increase (7.5% versus 8.7%, OR: 1.18, 95%CI: 0.92-1.52, p = 0.18). The overall frequency of recurrent headache changed towards more monthly and less weekly headache. Conclusions This is the first large-scale population-based study among adolescents in Norway assessing changes in the prevalence of primary headaches over a four-year period of time. The overall prevalence of recurrent headaches increased significantly from Young-HUNT 1 to Young-HUNT 2. An increase was seen in all types of recurrent headaches and was significant for tension-type headache. Implications Earlier follow-up studies have examined changes in prevalence of recurrent headaches in young age, but the results are diverging. Our findings support the impression that the prevalence of recurrent headache among adolescents is increasing, and underlines the need for prospective designed studies with emphasis on prognosis and etiological factors. AD - Department of Neurology, Vestfold Hospital, Tønsberg, Norway. Faculty of Medicine, University of Oslo, Oslo, Norway. Norwegian Centre for Violence and Traumatic Stress Studies, Oslo, Norway. Department of Neuroscience, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway. Norwegian National Headache Centre, Section of Neurology, St. Olavs Hospital, Trondheim, Norway. HUNT Research Centre, Department of Public Health, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway. Department of Neurology, Oslo University Hospital, Ullevå,Oslo, Norway. National Centre for Spinal Disorders, St. Olavs Hospital, Trondheim, Norway. AN - 29913741 AU - Jacobsena, B. A. AU - Dyb, G. AU - Hagen, K. AU - Stovner, L. J. AU - Holmen, T. L. AU - Zwart, J. A. DA - Jul 1 DO - 10.1016/j.sjpain.2011.03.002 DP - NLM ET - 2018/06/20 IS - 3 KW - Adolescents Epidemiology Headache Migraine Prevalence Tension-type headache LA - eng N1 - 1877-8879 Jacobsena, Brit A Dyb, Grete Hagen, Knut Stovner, Lars J Holmen, Turid L Zwart, John-Anker Journal Article Germany Scand J Pain. 2018 Jul 1;2(3):148-152. doi: 10.1016/j.sjpain.2011.03.002. PY - 2018 SN - 1877-8860 SP - 148-152 ST - The Nord-Trøndelag Health Study shows increased prevalence of primary recurrent headaches among adolescents over a four-year period T2 - Scand J Pain TI - The Nord-Trøndelag Health Study shows increased prevalence of primary recurrent headaches among adolescents over a four-year period VL - 2 ID - 4176 ER - TY - JOUR AB - Background: Use of opioids in the management of pain and its consequences in children presents a substantial challenge. A significant concern in pediatric pain management is the long-term neuropsychological consequences of opioids. Objectives: The authors aim to provide a descriptive review of the current literature surrounding the neuropsychological impact of opioid use in children, along with possible extrapolations from their use in adults and animal models. Study Design: Systematic review of published literature. Setting: Various universities in the United States. Methods: The electronic review for papers published between January 1992 and December 2012 was conducted using Medline/Pubmed, PsychInfo, CINAHL, the Cochrane Library database, and Google Scholar. Results: Findings assessing pediatric pain patients treated with opioids demonstrated no significant differences in intelligence, behavior, vocabulary, or motor skills. One study reported a decrease in a visuo-constructional ability, which measured higher order executive function. Studies from prenatal illicit opioid exposure found poorer performance on measures of language, verbal ability, mathematics, reading, impulse control, and school readiness skills. The literature from adult prescribed opioid users has mixed results. Some showed impairment in the neuropsychological domains of memory, decision-making, attention, concentration, information processing, psychomotor speed, visual special skills, and hand-eye coordination, while others found no differences or revealed improved perceptual-cognitive status, possibly due to the removal of pain as a stressor. Limitations: Very few studies looked into the long term neuropsychological and cognitive effects of the opioids in pediatric population. In an attempt to extrapolate from other groups, this review also included literature from adult patients, prenatal opioid exposure, and animal studies. Conclusion: Opioid medications have the potential to produce long-lasting neuropsychological side effects. However, given the negative consequences of untreated pain, the potential benefit may offset their risk. More studies are needed to clarify this complex interaction. AN - WOS:000344421100001 AU - Jain, G. AU - Mahendra, V. AU - Singhal, S. AU - Dzara, K. AU - Pilla, T. R. AU - Manworren, R. AU - Kaye, A. D. DA - Mar-Apr IS - 2 N1 - Jain, Gaurav Mahendra, Vijaita Singhal, Sarita Dzara, Kristina Pilla, Trinadha R. Manworren, Renee Kaye, Alan David Dzara, Kristina/0000-0001-9425-2679 PY - 2014 SN - 1533-3159 SP - 109-118 ST - Long-Term Neuropsychological Effects of Opioid Use in Children: A Descriptive Literature Review T2 - Pain Physician TI - Long-Term Neuropsychological Effects of Opioid Use in Children: A Descriptive Literature Review UR - ://WOS:000344421100001 VL - 17 ID - 2313 ER - TY - JOUR AB - The education of rheumatic patients in Croatia has begun in 1975 by introducing the school of back pain. Soon after that has begun the education of children with scoliosis. The education of patients with rheumatoid arthritis and ankylosing spondylitis was establish in 1985. Along with the courses of patient's education, there were printed a publications dedicated to the same problem. At the beginning there was printed a textbook Rheumatic diseases with training for rheumatic patients (1978.) and then textbook Jogging (1982.) and Reta (1984.). During 1994, there were graduated a publications dedicated to the disease having the same name: Rheumatoid arthritis, Ankylosing spondylitis, Uric arthritis and Psoriatic arthritis, which were reprinted in enlarged form (1997). Protection of the joints in rheumatic disease (1998.) is a new textbook for patients about correctly usage of the joints. Textbook Prevention of back pain and neck pain (1998.) is dedicated to healthy people for the prevention of pain syndromes of vertebra. Thus, the education was introduced in almost all parts of rheumatology and in whole Republic of Croatia. AD - Klinika za fizikalnu medicinu, rehabilitaciju i reumatologiju KB Sestre milosrdnice, Zagreb. AN - 9921007 AU - Jajić, Z. DP - NLM ET - 1999/01/28 IS - 1 KW - Croatia History, 20th Century Patient Education as Topic/*history Rheumatic Diseases/*history LA - hrv N1 - Jajić, Z English Abstract Historical Article Journal Article Croatia Reumatizam. 1998;46(1):31-4. OP - Povijesni razvoj edukacije reumatskih bolesnika u Hrvatskoj. PY - 1998 SN - 0374-1338 (Print) 0374-1338 SP - 31-4 ST - [History of patient education in rheumatic diseases in Croatia] T2 - Reumatizam TI - [History of patient education in rheumatic diseases in Croatia] VL - 46 ID - 4222 ER - TY - BOOK AB - Headache is a common complaint, occurring in the majority of school age children. The frequency increases with increasing age and the etiologies range from tension to life-threatening infections and brain tumors. Migraine is the most frequent cause of acute and recurrent headaches in children. Children are usually brought to medical attention to exclude serious causes, such as brain tumors or meningitis. A thorough history, physical and neurological examination, and appropriate diagnostic testing (if indicated) will enable the physician to distinguish tension and migraine headaches from those of a secondary etiology. Children with recurrent headaches are more likely to have certain migraine related phenomena, such as motion sickness, teeth grinding (bruxism), sleep talking and walking (somnambulism), and syncope. Most patients with migraine have type A personality, making them worry allot, perfectionist, and high achievers. This may provide further risks and potential triggers to the recurrent headaches. AN - WOS:000440951700020 AU - Jan, M. M. S. AU - Jan, M. M. S. N1 - Jan, Mohammed M. S. PY - 2012 SN - 978-1-60805-022-2; 978-1-60805-393-3 SP - 105-110 ST - Headache & Migraine T2 - Manual of Child Neurology: Problem Based Approach to Common Disorders TI - Headache & Migraine UR - ://WOS:000440951700020 ID - 2463 ER - TY - JOUR AB - Objective To examine whether school absenteeism is a perpetuating factor of functional somatic symptoms and whether this holds true for bullied adolescents. Study design This study is part of the longitudinal population-based study Tracking Adolescents' Individual Lives Survey. Data from assessment wave 2 (n = 2149; 51.0% girls; mean age = 13.65, SD = 0.53) and assessment wave 3 (n = 1816; 53.3% girls; mean age = 16.25, SD = 0.72) were used. Peer victimization was assessed by peer nominations, school absenteeism by both parent and teacher reports, and functional somatic symptoms with the Youth Self-Report. Results With structural equation modeling, school absenteeism at the second wave, adjusted for functional somatic symptoms at the second wave, was revealed to predict functional somatic symptoms at the third wave in the entire cohort (beta = 0.12; 95% CI, 0.02-0.22), but not in the subgroup of bullied adolescents (beta = -0.13; 95% CI, -0.62--0.26). However, the difference between bullied and unbullied adolescents did not reach significance. Conclusion This study provides evidence that school absenteeism is a perpetuating factor of functional somatic symptoms in adolescents. A clinical intervention study is necessary to examine whether preventing school absenteeism truly helps to reduce functional somatic symptoms in adolescents. (J Pediatr 2011;159:988-93). AN - WOS:000296849400022 AU - Janssens, K. A. M. AU - Oldehinkel, A. J. AU - Dijkstra, J. K. AU - Veenstra, R. AU - Rosmalen, J. G. M. DA - Dec DO - 10.1016/j.jpeds.2011.06.008 IS - 6 N1 - Janssens, Karin A. M. Oldehinkel, Albertine J. Dijkstra, Jan Kornelis Veenstra, Rene Rosmalen, Judith G. M. Dijkstra, Jan/E-9338-2013; Veenstra, Rene/G-6696-2011; Rosmalen, Judith G.M./F-5375-2011 Veenstra, Rene/0000-0001-6686-6307; Rosmalen, Judith G.M./0000-0002-6393-0032 1097-6833 PY - 2011 SN - 0022-3476 SP - 988-U155 ST - School Absenteeism as a Perpetuating Factor of Functional Somatic Symptoms in Adolescents: The TRAILS Study T2 - Journal of Pediatrics TI - School Absenteeism as a Perpetuating Factor of Functional Somatic Symptoms in Adolescents: The TRAILS Study UR - ://WOS:000296849400022 VL - 159 ID - 2469 ER - TY - JOUR AB - Introduction: Pain is defined as an unpleasant sensory or emotional experience associated with actual or potential harm is more complex human experience, and despite the importance of this symptom is often underestimated. Objective: Describe how pain management is offered by the nursing staff of the pediatric patient after surgery appendectomy. Materials and Methods: Descriptive, no experimental, exploratory, quantitative approach, we used a semi-structured instrument that was applied to staff nurses working in the area of pediatrics at a second level hospital in the city of Durango, this instrument consists of seven items. Results: 55% of the sample only uses the ministry as dependent action of analgesics to manage pain, while (45%) also performed other independent operations as part of nursing care. 45% of nurses engaged in other interventions yielded the following results: emotional support (56%), position change (22%), environmental management (11%) and the OMS analgesic ladder (11%). Discussion: The results obtained are not clearly reflect that the higher academic level more typical of nursing interventions would be made to provide pain relief, so that more effective management, some authors are agree with our results because, although they are some guidelines for postoperative pain management is also necessary to change behavior. Conclusions: Exposed above the need to develop an innovative model in which nurses in the pediatric ward apply its own independent nursing interventions, in order to improve the quality of care in the management of postoperative pain in patient's appendectomy. AN - WOS:000215614600005 AU - Jaquez, A. G. C. AU - Rivas, M. K. O. AU - Enciso, H. M. S. AU - Avendano, D. J. G. IS - 1 N1 - Cordova Jaquez, Anabel Guadalupe Ortiz Rivas, Miriam Karma Salazar Enciso, Hilda Manuela Garcia Avendano, David Jahel 2346-3414 PY - 2012 SN - 2216-0973 SP - 287-292 ST - PAIN MANAGEMENT BY THE NURSING STAFF IN PEDIATRIC PATIENT POST-SURGICAL APPENDECTOMY T2 - Revista Cuidarte TI - PAIN MANAGEMENT BY THE NURSING STAFF IN PEDIATRIC PATIENT POST-SURGICAL APPENDECTOMY UR - ://WOS:000215614600005 VL - 3 ID - 2464 ER - TY - JOUR AB - Anxiety is highly prevalent in pediatric chronic pain. This comorbidity has been explained by the presence of shared mechanisms underlying the development and maintenance of chronic pain and anxiety. Accumulating evidence demonstrates that school is a significant source of anxiety among youth with chronic pain and that anxiety contributes to school-related functional impairment in this population. This article reviews the cooccurrence of pediatric chronic pain and anxiety, identifies unique sources of heightened school anxiety among youth with chronic pain, and describes current approaches for assessing anxiety in pediatric pain settings. Highlighted by this review is the absence of a comprehensive evidence-based approach for assessing school anxiety in pediatric chronic pain. Given the psychometric limitations inherent to gathering data from a single source, recommendations for advancing measurement methods are provided. Novel approaches may be needed to shed more light on the way in which school anxiety is experienced in pediatric chronic pain. AU - Jastrowski Mano, K. E. DA - 2017 DO - 10.1155/2017/8328174 DP - PubMed J2 - Pain Res Manag KW - Activities of Daily Living Adaptation, Psychological Adolescent Anxiety Child Chronic Pain Humans Schools LA - eng PY - 2017 SN - 1918-1523 SP - 8328174 ST - School Anxiety in Children and Adolescents with Chronic Pain T2 - Pain Research & Management TI - School Anxiety in Children and Adolescents with Chronic Pain UR - http://www.ncbi.nlm.nih.gov/pubmed/29081682 VL - 2017 ID - 67 ER - TY - JOUR AB - The prevalence of functional gastrointestinal disorders (FGIDs) in children in Ecuador is unknown. We describe a survey study in 2 schools in Quito, Ecuador, using a Spanish translation of the Questionnaire on Pediatric Gastrointestinal Symptoms-Rome III Version (QPGS-RIII). A total of 417 children (51% boys) with a mean age of 12.0 years were included. FGIDs were present in 95 children (22.8%) and occurred in 25% of girls and in 20.7% of boys (P = 0.296). Functional defecation disorders were found in 12.0% of children, 9.4% had an abdominal pain-related FGID and 3.8% was diagnosed with a vomiting or aerophagia FGID. AN - WOS:000378692400017 AU - Jativa, E. AU - Velasco-Benitez, C. A. AU - Koppen, I. J. N. AU - Jativa-Cabezas, Z. AU - Saps, M. DA - Jul DO - 10.1097/mpg.0000000000001108 IS - 1 N1 - Jativa, Edgar Velasco-Benitez, Carlos A. Koppen, Ilan J. N. Jativa-Cabezas, Zahira Saps, Miguel Koppen, Ilan J.N./AAA-6800-2020 Koppen, Ilan J.N./0000-0002-1856-0968; Velasco-Benitez, Carlos Alberto/0000-0002-4062-5326; Velasco-Benitez, Carlos A/0000-0001-5647-3024 1536-4801 PY - 2016 SN - 0277-2116 SP - 25-28 ST - Prevalence of Functional Gastrointestinal Disorders in Schoolchildren in Ecuador T2 - Journal of Pediatric Gastroenterology and Nutrition TI - Prevalence of Functional Gastrointestinal Disorders in Schoolchildren in Ecuador UR - ://WOS:000378692400017 VL - 63 ID - 2158 ER - TY - JOUR AB - Background: The second Swiss Multicenter Adolescent Survey on Health (SMASH02) was conducted among a representative sample (n = 7428) of students and apprentices aged 16 to 20 from the three language areas of Switzerland during the year 2002. This paper reports on health needs expressed by adolescents and their use of health care services over the 12 months preceding the survey. Methods: Nineteen cantons representing 80% of the resident population agreed to participate. A complex iterative random cluster sample of 600 classes was drawn with classes as primary sampling unit. The participation rate was 97.7% for the classes and 99.8% for the youths in attendance. The self-administered questionnaire included 565 items. The median rate of item non-response was 1.8%. Ethical and legal requirements applying to surveys of adolescent populations were respected. Results: Overall more than 90% of adolescents felt in good to excellent health. Suffering often or very often from different physical complaints or pain was also reported such as headache (boys: 15.9%, girls: 37.4%), stomach-ache (boys: 9.7%, girls: 30.0%), joint pain (boys: 24.7%, girls: 2 9.5 %) or back pain (boys: 24.3 %, girls: 34.7 %). Many adolescents reported a need for help on psychosocial and lifestyle issues, such as stress (boys: 28.5%, girls: 47.7%) or depression (boys: 18.9%, girls: 34.4%). Although about 75% of adolescents reported having consulted a general practitioner and about one-third having seen another specialist, reported reasons for visits do not correspond to the expressed needs. Less than 10% of adolescents had visited a psychiatrist, a family planning centre or a social worker. Conclusions: The reported rates of health services utilisation by adolescents does not match the substantial reported needs for help in various areas. This may indicate that the corresponding problems are not adequately detected and/or addressed by professionals from the health and social sectors. AN - WOS:000226658700003 AU - Jeannin, A. AU - Narring, F. AU - Tschumper, A. AU - Bonivento, L. I. AU - Addor, V. AU - Butikofer, A. AU - Suris, J. C. AU - Diserens, C. AU - Alsaker, F. AU - van Melle, G. AU - Michaud, P. A. DA - Jan IS - 1-2 N1 - Jeannin, A Narring, F Tschumper, A Bonivento, LI Addor, V Butikofer, A Suris, JC Diserens, C Alsaker, F van Melle, G Michaud, PA Michaud, Pierre-Andre/C-6355-2009; Suris, Joan-Carles/C-5897-2009 PY - 2005 SN - 1424-7860 SP - 11-18 ST - Self-reported health needs and use of primary health care services by adolescents enrolled in post-mandatory schools or vocational training programmes in Switzerland T2 - Swiss Medical Weekly TI - Self-reported health needs and use of primary health care services by adolescents enrolled in post-mandatory schools or vocational training programmes in Switzerland UR - ://WOS:000226658700003 VL - 135 ID - 2775 ER - TY - JOUR AB - In this study, we compared several aspects of the emotional functioning of schoolchildren reporting very few somatic complaints (n = 59), schoolchildren reporting many somatic complaints (n = 61), and a clinical group of children with functional abdominal complaints who visited the outpatient clinical of the VU University Medical Centre in Amsterdam (n = 33). The children had an average age of 10.6 years. We studied whether general moods (happiness, anger, fear, and sadness), symptoms of depressiveness, emotion awareness, and sense of coherence contributed to group classification. Eighty-three percent of the schoolchildren reporting very few somatic complaints were identified correctly on the basis of better emotional functioning. However, there was little difference in the emotional functioning of schoolchildren with many somatic complaints and that of the clinical group. We concluded that the variables studied are valuable for differentiating children who are troubled by somatic complaints from children experiencing few somatic complaints. The results stress the existence of emotional problems in children reporting many somatic complaints. (c) 2006 Elsevier Ltd. All rights reserved. AN - WOS:000241653600009 AU - Jellesma, F. C. AU - Rieffe, C. AU - Meerum Terwogt, M. AU - Kneepkens, C. M. F. DA - Nov DO - 10.1016/j.socscimed.2006.07.004 IS - 10 N1 - Jellesma, Francine C. Rieffe, Carolien Meerum Terwogt, Mark Kneepkens, C. M. Frank Rieffe, Carolien/0000-0002-7584-6698; Kneepkens, C M Frank/0000-0001-5415-7319 PY - 2006 SN - 0277-9536 SP - 2640-2648 ST - Somatic complaints and health care use in children: Mood, emotion awareness and sense of coherence T2 - Social Science & Medicine TI - Somatic complaints and health care use in children: Mood, emotion awareness and sense of coherence UR - ://WOS:000241653600009 VL - 63 ID - 2715 ER - TY - JOUR AB - Objective: To evaluate the Somatic Complaint List (SCL) in children. Method: At T1, 365 fourth and 352 fifth graders completed the SCL, the Children's Somatization Inventory (CSI-C), and the Mood Questionnaire. Parents (n=564) completed the parental form of the CSI-C (CSI-P). Six months later, the stability of the SCL and the CSI-C was assessed. Results: The psychometric properties and stability of the SCL were good. Correlations with the CSI-C, negative moods, and the CSI-P complaints supported the validity. Moreover, the SCL was more strongly associated with negative moods and with parental reports of children's somatic complaints than the CSI-C. Conclusion: The SCL is a suitable questionnaire for assessing somatic complaints in school-aged children. (c) 2007 Elsevier Inc. All rights reserved. AN - WOS:000250120100009 AU - Jellesma, F. C. AU - Rieffe, C. AU - Terwogt, M. M. DA - Oct DO - 10.1016/j.jpsychores.2007.01.017 IS - 4 N1 - Jellesma, Francine C. Rieffe, Carolien Terwogt, Mark Meerurn Rieffe, Carolien/0000-0002-7584-6698 1879-1360 PY - 2007 SN - 0022-3999 SP - 399-401 ST - The somatic complaint list: Validation of a self-report questionnaire assessing somatic complaints in children T2 - Journal of Psychosomatic Research TI - The somatic complaint list: Validation of a self-report questionnaire assessing somatic complaints in children UR - ://WOS:000250120100009 VL - 63 ID - 2678 ER - TY - JOUR AB - The objective of this study was to investigate the prospective relationships between sense of coherence, trait emotional intelligence and children's somatic complaints. The study included four waves of data collection with six months in between each wave. Participants were 324 girls and 393 boys (mean age = 10 years and 3 months, SD = 8.5 months) at the first time of data collection. The children filled out self-report questionnaires concerning their somatic complaints, sense of coherence and trait emotional intelligence. Multilevel model analyses were carried out that included cross-sectional and longitudinal effects of sense of coherence and trait emotional intelligence on children's somatic complaints. The results showed that higher levels of trait emotional intelligence and a stronger sense of coherence were associated with fewer somatic complaints in children. These relationships seemed to be bidirectional. AN - WOS:000287491800004 AU - Jellesma, F. C. AU - Rieffe, C. AU - Terwogt, M. M. AU - Westenberg, P. M. C7 - Pii 920065609 DO - 10.1080/08870440903411021 IS - 3 N1 - Jellesma, Francine C. Rieffe, C. Terwogt, Mark Meerum Westenberg, P. M. Westenberg, P. Michiel/AAA-6390-2021 Rieffe, Carolien/0000-0002-7584-6698 1476-8321 PY - 2011 SN - 0887-0446 SP - 307-320 ST - Children's sense of coherence and trait emotional intelligence: A longitudinal study exploring the development of somatic complaints T2 - Psychology & Health TI - Children's sense of coherence and trait emotional intelligence: A longitudinal study exploring the development of somatic complaints UR - ://WOS:000287491800004 VL - 26 ID - 2526 ER - TY - JOUR AB - The usefulness of the verbal pain rating scale (VRS) included in the Short Form 36 (SF-36) in identifying characteristics of long-term pain conditions, was analyzed using data from the 1994 Danish Health and Morbidity Survey. Based on the rating of pain intensity during a 4-week recall period the respondents were categorized into three groups: a high pain group (HPG) consisting of persons reporting moderate to severe pain (VRS 4-6), a low pain group (LPG) who rated their pain as very mild or mild (VRS 2-3), and a control group (CG) with no pain (VRS 1). The investigated sample comprised 3992 persons (HPG=563 persons, LPG=1714, and CG=1715 persons). Older age, educational level (< 10 years of schooling), cohabitation status (divorce/separation), and moderate to severe physical job strain were found to be significant risk factors for reporting high pain intensity (HPG). Only minor differences were observed between the LPG and CG. The proportion of respondents with good perceived health was significantly lower in the HPG compared with LPG and CG. The dominant complaints in the HPG were related to the musculoskeletal system. During a 14-day period prior to the interview persons in the HPG had a mean of 1.19 working days lost due to illness compared with a mean of 0.2 for the LPG and CG. Analyzing the use of medical services during the year before the interview, persons belonging to the HPG had an average number of nine contacts to general practitioners and specialized doctors in the primary sector as compared to six for the LPG and four for the CG. Mean numbers of hospital admissions were 0.29 for the HPG, 0.15 for the LPG and 0.10 for the CG. Mean numbers of in-hospital days were 1.60, 0.80, and 0.43 for the HPG, LPG, and CG, respectively. Our study suggest that one-dimensional pain intensity scoring using a simple VRS-scoring is useful as a screening instrument for identifying persons suffering from pain of a more complex nature. High intensity scores on a pain intensity scale should indicate to the investigator that she/he might be facing a person whose pain complaints and behavior are not only based on a pure biological background, but in whom also severe psychological and social problems might be present. AD - Multidisciplinary Pain Centre, H:S Rigshospitalet, Dept. 7612, Rigshopitalet Blegdamsvej 9, Copenhagen DK-2100, Denmark. AN - 14987624 AU - Jensen, M. K. AU - Sjøgren, P. AU - Ekholm, O. AU - Rasmussen, N. K. AU - Eriksen, J. DA - Apr DO - 10.1016/s1090-3801(03)00088-0 DP - NLM ET - 2004/02/28 IS - 2 KW - Adolescent Adult Aged Chronic Disease Denmark Disability Evaluation Epidemiologic Studies Female Health Status Humans Male Middle Aged Pain/complications/*diagnosis/psychology *Pain Measurement Patient Acceptance of Health Care Reproducibility of Results Socioeconomic Factors Time Factors LA - eng N1 - Jensen, Marianne Kjettrup Sjøgren, Per Ekholm, Ola Rasmussen, Niels Kristian Eriksen, Jørgen Journal Article Research Support, Non-U.S. Gov't England Eur J Pain. 2004 Apr;8(2):145-52. doi: 10.1016/S1090-3801(03)00088-0. PY - 2004 SN - 1090-3801 (Print) 1090-3801 SP - 145-52 ST - Identifying a long-term/chronic, non-cancer pain population using a one-dimensional verbal pain rating scale: an epidemiological study T2 - Eur J Pain TI - Identifying a long-term/chronic, non-cancer pain population using a one-dimensional verbal pain rating scale: an epidemiological study VL - 8 ID - 3520 ER - TY - JOUR AB - ObjectiveTo examine work absenteeism, job disruptions, and perceived productivity loss and factors associated with each outcome in young adults living with systemic lupus erythematosus (SLE) and juvenile arthritis (JA). MethodsOne hundred forty-three young adults, ages 18-30 years with SLE (54.5%) and JA (45.5%), completed an online survey of work experiences. Demographic, health (e.g., fatigue, disease activity), psychosocial (e.g., independence, social support), and work context (e.g., career satisfaction, job control, self-disclosure) information was collected. Participants were asked about absenteeism, job disruptions, and perceived productivity loss in the last 6 months. Log Poisson regression analyses examined factors associated with work outcomes. ResultsA majority of participants (59%) were employed and reported a well-managed health condition. Employed respondents were satisfied with their career progress and indicated moderate job control. More than 40% of participants reported absenteeism, job disruptions, and productivity loss. Greater job control and self-disclosure, and less social support, were related to a higher likelihood of absenteeism. More disease activity was related to a greater likelihood of reporting job disruptions. Lower fatigue and higher job control were associated with a reduced likelihood of a productivity loss. ConclusionYoung adult respondents with rheumatic disease experienced challenges with employment, including absenteeism, job disruptions, and productivity loss. While related to greater absenteeism, job control could play a role in a young person's ability to manage their health condition and sustain productive employment. Greater attention should also be paid to understanding health factors and social support in early work experiences. AN - WOS:000360390400008 AU - Jetha, A. AU - Badley, E. AU - Beaton, D. AU - Fortin, P. R. AU - Shiff, N. J. AU - Gignac, M. A. M. DA - Sep DO - 10.1002/acr.22601 IS - 9 N1 - Jetha, Arif Badley, Elizabeth Beaton, Dorcas Fortin, Paul R. Shiff, Natalie J. Gignac, Monique A. M. Jetha, Arif/0000-0003-0322-7027; Fortin, Paul R./0000-0002-7278-2596 2151-4658 PY - 2015 SN - 2151-464X SP - 1246-1254 ST - Unpacking Early Work Experiences of Young Adults With Rheumatic Disease: An Examination of Absenteeism, Job Disruptions, and Productivity Loss T2 - Arthritis Care & Research TI - Unpacking Early Work Experiences of Young Adults With Rheumatic Disease: An Examination of Absenteeism, Job Disruptions, and Productivity Loss UR - ://WOS:000360390400008 VL - 67 ID - 2225 ER - TY - JOUR AB - Objective: The aim of this study was to investigate the health-related quality of life (HRQOL) in 2-7-year-old children diagnosed with recurrent respiratory tract infections (RRTIs) and the impact of RRTIs on affected families. Methods: This was a cross-sectional case-control study evaluating 2-7-year-old children with RRTIs (n = 352), 2-7-year-old healthy children (n = 376), and associated caregivers (parents and/or grandparents). A Chinese version of the PedsQL (TM) 4.0 Generic Core Scale was used to assess childhood HRQOL, and a Chinese version of the Family Impact Module (FIM) was used to assess the impact of RRTIs on family members. HRQOL scores were compared between children with RRTIs and healthy children. In addition, a multiple step-wise regression with demographic variables of children and their caregivers, family economic status, and caregiver's HRQOL as independent variables determined factors that influenced HRQOL in children with RRTIs. Results: Children with RRTIs showed significantly lower physical, emotional, social, and school functioning scores than healthy children (p<0.05). Caregivers for children with RRTIs also scored significantly lower than caregivers for healthy children on physical, emotional, social, cognitive, and communication functioning (p<0.05). Caregivers for RRTIs affected children also reported significantly higher levels of worry. Multivariate analyses showed that children's age, children's relation with caregivers, the frequency of respiratory tract infections in the preceding year, caregiver's educational level, and caregiver's own HRQOL influenced HRQOL in children with RRTIs. Conclusions: The current data demonstrated that RRTIs were associated with lower HRQOL in both children and their caregivers and negatively influenced family functioning. In addition, caregivers' social characteristics also significantly affected HRQOL in children with RRTIs. AN - WOS:000316849500045 AU - Jiang, X. AU - Sun, L. J. AU - Wang, B. X. AU - Yang, X. J. AU - Shang, L. AU - Zhang, Y. H. C7 - e56945 DA - Feb DO - 10.1371/journal.pone.0056945 IS - 2 N1 - Jiang, Xun Sun, Lijun Wang, Baoxi Yang, Xianjun Shang, Lei Zhang, Yuhai PY - 2013 SN - 1932-6203 ST - Health-Related Quality of Life among Children with Recurrent Respiratory Tract Infections in Xi'an, China T2 - Plos One TI - Health-Related Quality of Life among Children with Recurrent Respiratory Tract Infections in Xi'an, China UR - ://WOS:000316849500045 VL - 8 ID - 2381 ER - TY - JOUR AB - In recent years, fatigue is common among adolescents. The aim of this study is to evaluate fatigue status and find related factors of fatigue among students ranged from 13-26 years from Wuhu, China. This is a case-control, cross-sectional observational study. The students from six middle schools (high school? 26 years old?) in Wuhu city were recruited, Self-Rating Fatigue Scale (SFS) was used to measure the fatigue status among students ranged from 13-26 years, and some demographic characteristics of students also was determined. A total of 726 students are included in our study. A significant difference was observed between fatigue status and grade, a balanced diet, the partial eclipse, picky for food, lack of sleep, excessive fatigue, drinking (P < 0.05). The risk factors of fatigue status include myopia, partial eclipse, picky for food, lacking of sleep, drinking; grade while a balanced diet is the protective factor of fatigue. Therefore, the school should pay more attention to the fatigue among students in middle school in China, and take some properly measures to reduce the fatigue. AN - WOS:000367669800297 AU - Jin, Y. L. AU - Peng, B. Z. AU - Li, Y. J. AU - Song, L. AU - He, L. P. AU - Fu, R. AU - Wu, Q. Q. AU - Fan, Q. X. AU - Yao, Y. S. IS - 10 N1 - Jin, Yuelong Peng, Baozhen Li, Yijun Song, Lei He, Lianping Fu, Rui Wu, Qianqian Fan, Qingxiu Yao, Yingshui he, lianping/AAG-4256-2020; , helianping/C-3592-2017 he, lianping/0000-0002-9627-5599; , helianping/0000-0002-9627-5599; Yao, Ying-Shui/0000-0002-6690-4585 PY - 2015 SN - 1940-5901 SP - 19442-19447 ST - Risk factors of fatigue status among Chinese adolescents T2 - International Journal of Clinical and Experimental Medicine TI - Risk factors of fatigue status among Chinese adolescents UR - ://WOS:000367669800297 VL - 8 ID - 2253 ER - TY - JOUR AB - Neurobiological mechanisms can be involved in early programming of pain sensitization. We aimed to investigate the association between early-life pain experience and pre-adolescence spinal pain. We conducted a study of 29,861 pre-adolescents (age 11-14) from the Danish National Birth Cohort. As indicators of early-life pain, we used infantile colic and recurrent otitis media, reported by mothers when their children were 6 and 18 months. Self-reported spinal pain (neck, middle back, and/or low back pain) was obtained in the 11-year follow-up, classified according to severity. Associations between early-life pain and spinal pain in pre-adolescents were estimated using multinomial logistic regression models. To account for sample selection, inverse probability weighting was applied. Children experiencing pain in early life were more likely to report severe spinal pain in pre-adolescence. The association appeared stronger with exposure to two pain exposures (relative risk ratio, 1.31; 95% CI, 1.02-1.68) rather than one (relative risk ratio, 1.14; 95% CI, 1.05-1.24). We observed similar results when using headache and abdominal pain as outcome measures, underpinning a potential neurobiological or psychosocial link in programming of pain sensitization. Conclusion: Experience of early-life pain is seemingly associated with spinal pain in pre-adolescence. The study highlights that early-life painful experiences can influence programming future pain responses.What is Known:center dot Spinal pain in pre-adolescents is common, causes marked discomfort and impairment in everyday life, and may be an important predictor of spinal pain later in life.center dot Neurobiological mechanisms have been suggested as involved in early programming of pain sensitization.What is New:center dot Pain exposure in early postnatal life in terms of infantile colic and recurrent otitis media is associated with spinal pain in pre-adolescence; thus, experience of such painful conditions in the early postnatal period may seemingly influence programming of future pain sensation. AN - WOS:000490853800001 AU - Joergensen, A. C. AU - Lucas, R. AU - Hestbaek, L. AU - Andersen, P. K. AU - Andersen, A. M. N. DA - Dec DO - 10.1007/s00431-019-03475-9 IS - 12 N1 - Joergensen, Anne Cathrine Lucas, Raquel Hestbaek, Lise Andersen, Per Kragh Nybo Andersen, Anne-Marie ; Hestbaek, Lise/K-1933-2015; Nybo Andersen, Anne-Marie/E-4993-2013 Lucas, Raquel/0000-0002-4408-8134; Hestbaek, Lise/0000-0002-1620-4556; Nybo Andersen, Anne-Marie/0000-0002-4296-8488; Jorgensen, Anne Cathrine/0000-0002-8845-4204 1432-1076 PY - 2019 SN - 0340-6199 SP - 1903-1911 ST - Early-life programming of pain sensation? Spinal pain in pre-adolescents with pain experience in early life T2 - European Journal of Pediatrics TI - Early-life programming of pain sensation? Spinal pain in pre-adolescents with pain experience in early life UR - ://WOS:000490853800001 VL - 178 ID - 1876 ER - TY - JOUR AB - PURPOSE: To describe clinical features, issues related to school life and health-related quality of life (HRQOL) for children with congenital limb deficiency (CLD) and compare these children to Norwegian school children on HRQOL. METHOD: Cross-sectional study. In 2010, a postal questionnaire, designed for this study and the Paediatric Quality of Life Inventory (PedsQL), was sent to 154 eligible parents of children with CLD, aged 6-18 years and registered at TRS National Resource Centre for Rare Disorders in Norway. RESULTS: Response rate 44% (n = 67), median age 11 years, 42% were girls. Of the total group, 46 had unilateral upper limb deficiency (UULD) and 21 had multiple/lower limb deficiency (MLD/LLD). The most common UULD was below-elbow deficiency, of these, 65% used grip-improving devices, and 35% used prostheses. Children with UULD-reported PedsQL score similar to Norwegian schoolchildren (NSC). The MLD/LLD group was heterogeneous; most had below-elbow/knee deficiency. In this group, PedsQL scores were reduced for physical and social functioning compared with NSC. Compared with children with UULD, more children with MLD/LLD were restricted in participation because of pain and fewer participated in physical education with peers. CONCLUSIONS: Most children with CLD participated with their peers and managed well in everyday life. Children with MLD/LLD seemed to have more challenges than children with UULD. Approximately one-third of all the children had assistive devices and/or practical assistance in school. Implications for Rehabilitation Most children with upper-limb deficiency (UULD) in Norway manage well in everyday life and have HRQOL equal to other Norwegian children. Many choose grip-improving devices instead of prostheses. Their preferences should be respected and taken into account as the need for new assistive devices arise. For children with pronounced disabilities, access to, and use of, assistive devices, adaptions and practical assistance may be important for participation. Cooperation with the child and the parents is necessary to find useful measures. Physical education and practical subjects may provide special challenges, both for children and their teachers. Children themselves often find good solutions and the tasks should be planned ahead in cooperation with them. AD - a Sunnaas Rehabilitation Hospital, TRS, National Resource Centre for Rare Disorders , Nesodden , Norway. AN - 26763295 AU - Johansen, H. AU - Dammann, B. AU - Øinæs Andersen, L. AU - Andresen, I. L. DA - Sep DO - 10.3109/09638288.2015.1107770 DP - NLM ET - 2016/01/15 IS - 18 KW - Adolescent Child Cross-Sectional Studies Disabled Persons/*rehabilitation Female Humans Limb Deformities, Congenital/*rehabilitation Male Norway Pain Management Quality of Life/*psychology Schools Self-Help Devices/statistics & numerical data Surveys and Questionnaires *Children *Norway *congenital limb deficiency *health-related quality of life *lower limb deficiency *multiple limb deficiency *school life *upper limb deficiency LA - eng N1 - 1464-5165 Johansen, Heidi Dammann, Brede Øinæs Andersen, Liv Andresen, Inger-Lise Journal Article England Disabil Rehabil. 2016 Sep;38(18):1803-10. doi: 10.3109/09638288.2015.1107770. Epub 2016 Jan 13. PY - 2016 SN - 0963-8288 SP - 1803-10 ST - Children with congenital limb deficiency in Norway: issues related to school life and health-related quality of life. A cross-sectional study T2 - Disabil Rehabil TI - Children with congenital limb deficiency in Norway: issues related to school life and health-related quality of life. A cross-sectional study VL - 38 ID - 3479 ER - TY - JOUR AB - BACKGROUND: Chronic non-cancer pain (CNCP) among patients with substance use disorder (SUD) poses a risk for worse treatment outcomes. Understanding the association of CNCP with SUD is important for informing the need and potential benefits of pain assessment/management among those with SUDs. METHODS: We analyzed electronic health record data from 2013 to 2018 among adults aged ≥18 years (N = 951,533; mean age: 48.4 years; 57.4 % female) in a large academic healthcare system. Adjusted logistic regression models were conducted to estimate the association of CNCP conditions with opioid overdose, emergency department utilization, and inpatient hospitalization stratified by different SUD diagnoses and by gender. RESULTS: Among the total sample, the prevalence of CNCP was 46.6 % and any SUD was 11.2 %. The majority of patients with a SUD had CNCP (opioid: 74.7 %; sedative: 72.3 %; cannabis: 64.3 %; alcohol: 58.7 %; tobacco: 59.5 %). The prevalence of CNCP was greater in females vs. males for most SUD diagnoses. The presence of CNCP was associated with more mental health disorders and chronic medical conditions among each SUD group. CNCP was associated with significantly decreased odds of overdose among those with opioid use disorder but increased odds of overdose and healthcare utilization among other SUDs. CNCP was positively associated with overdose in females, but not males, with alcohol or non-opioid drug use disorders. CONCLUSIONS: The direction and magnitude of the association between CNCP and negative health indicators differed as a function of SUD type and gender, respectively. Greater awareness of potential unmet pain treatment need may have implications for improving SUD outcomes. AD - Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA. Electronic address: william.john@duke.edu. Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA; Department of Medicine, Division of General Internal Medicine, Duke University Medical Center, Durham, NC, USA; Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA; Center for Child and Family Policy, Sanford School of Public Policy, Duke University, Durham, NC, USA. Electronic address: litzy.wu@duke.edu. AN - 32088587 AU - John, W. S. AU - Wu, L. T. C2 - PMC7127943 C6 - NIHMS1567472 DA - Apr 1 DO - 10.1016/j.drugalcdep.2020.107902 DP - NLM ET - 2020/02/24 KW - Adolescent Adult Aged Aged, 80 and over Analgesics, Opioid/*adverse effects/therapeutic use Chronic Pain/*drug therapy/*epidemiology/psychology Electronic Health Records/trends Emergency Service, Hospital/trends Female Humans Male Middle Aged Opiate Overdose/*epidemiology/psychology Opioid-Related Disorders/drug therapy/epidemiology/psychology Pain Management/*methods/trends *Patient Acceptance of Health Care/psychology Prevalence Treatment Outcome Young Adult *Chronic pain *Drug overdose *Healthcare utilization *Opioid *Substance use disorder Patient-Centered Outcomes Research Institute. Li-Tzy Wu has also received research funding from Patient-Centered Outcomes Research Institute, as well as from the Centers for Disease Control and Prevention, Duke Endowment, and Alkermes Inc. LA - eng N1 - 1879-0046 John, William S Wu, Li-Tzy R01 MD007658/MD/NIMHD NIH HHS/United States UG1 DA040317/DA/NIDA NIH HHS/United States Journal Article Multicenter Study Research Support, N.I.H., Extramural Drug Alcohol Depend. 2020 Apr 1;209:107902. doi: 10.1016/j.drugalcdep.2020.107902. Epub 2020 Feb 11. PY - 2020 SN - 0376-8716 (Print) 0376-8716 SP - 107902 ST - Chronic non-cancer pain among adults with substance use disorders: Prevalence, characteristics, and association with opioid overdose and healthcare utilization T2 - Drug Alcohol Depend TI - Chronic non-cancer pain among adults with substance use disorders: Prevalence, characteristics, and association with opioid overdose and healthcare utilization VL - 209 ID - 3065 ER - TY - JOUR AB - BACKGROUND: Pain in children with cerebral palsy (CP) has its sources in musculoskeletal problems that can influence learning in a school setting. Best pain management is essential for these children, but school staff may not keep up to date with the latest developments and interventions. Therefore, staff's perceptions of beneficial strategies may not comply with contemporary scientific knowledge about effective evidence-based interventions. OBJECTIVES: This study investigated how pain management intervention for children with CP in South African schools complied with international scientific knowledge about evidence-based interventions. The intention was to provide support for an update of knowledge on both individual level (i.e. professionals) and system level (i.e. decision makers). METHOD: Five focus groups were conducted with staff members at five schools for children with special educational needs in South Africa. Manifest and latent content analyses of professional statements identified interventions reported as beneficial and related them to higher and lower levels of intervention evidence as reported at the time of data collection. RESULTS: Most treatment strategies concerned motor functioning that fell within the framework of physiotherapists and occupational therapists. Access to orthopaedic expertise was limited, waiting times were long and medication for spasticity treatment was not offered. CONCLUSION: A discrepancy between published evidence and clinical practice for pain management in children with CP in South African school settings was noted. Suggestions for improved early intervention to identify children's hips at risk through surveillance programmes; and orthopaedic management are proposed to prevent deformities and unnecessary suffering in South African children with CP. AD - Centre for Augmentative and Alternative Communication, Faculty of Humanities, University of Pretoria, Pretoria, South Africa. Children, Health, Intervention, Learning and Development (CHILD), Jönköping University, Jönköping, Sweden. Institute of Health and Care Sciences, University of Gothenburg, Gothenburg, Sweden. School of Education and Communication, Jönköping University, Jönköping, Sweden. Swedish Institute of Disability Research, Jönköping University, Jönköping, Sweden. AN - 31824834 AU - Johnson, E. AU - Nilsson, S. AU - Adolfsson, M. C2 - PMC6890561 DO - 10.4102/ajod.v8i0.575 DP - NLM ET - 2019/12/12 IS - 0 KW - children with cerebral palsy clinicians evidence-based practice intervention pain management have inappropriately influenced them in writing this article. LA - eng N1 - 2226-7220 Johnson, Ensa Orcid: 0000-0001-6203-1433 Nilsson, Stefan Orcid: 0000-0003-2160-1983 Adolfsson, Margareta Orcid: 0000-0001-9917-813x Journal Article Afr J Disabil. 2019 Nov 22;8(0):575. doi: 10.4102/ajod.v8i0.575. eCollection 2019. PY - 2019 SN - 2223-9170 (Print) 2223-9170 SP - 575 ST - How pain management for children with cerebral palsy in South African schools complies with up-to-date knowledge T2 - Afr J Disabil TI - How pain management for children with cerebral palsy in South African schools complies with up-to-date knowledge VL - 8 ID - 4224 ER - TY - JOUR AB - CONTEXT: Information about the characteristics of patients who use osteopathic manipulative treatment (OMT) is limited. OBJECTIVE: To determine the scope of conditions being managed with OMT and describe the characteristics of patients who receive OMT. METHODS: Researchers conducted a longitudinal, observational study on the use and effectiveness of OMT at 17 clinics where clinicians (ie, osteopathic and allopathic physicians and Canadian-trained osteopaths) provided OMT. Adult patients receiving OMT completed questionnaires immediately before, immediately after, and daily for 7 days after treatment. Data collected from patients included demographic information, chief complaint(s) and their severity, and health-related quality of life. Physical examination findings, treatment, and medical diagnosis documentation were extracted from medical records. Census data were used to assess whether patients were representative of the population of the county where the clinic was located. RESULTS: Data were collected from 927 patients at 1924 office visits. A majority of patients were women (690 [75%]), white (854 [96%]), and not Hispanic or Latinx (707 [95%]). The mean (SD) age was 51.9 (15.9) years. When compared with census data, the sample had higher percentages of women, people aged 65 years and older, people who identified as white, people who were high school and college graduates, and people with higher household incomes than that of the county population. The most common chief complaints from patients were pain or discomfort in the lower back (311 [34%]) and neck (277 [30%]), which corresponded with the most common medical diagnoses. Patients reported that OMT, surgery, and medications were the most helpful treatments they had used previously for their chief complaint(s). Before receiving OMT, patients' health-related quality of life was significantly worse (P≤.05) than that of the general US population. CONCLUSIONS: Adult patients receiving OMT are being treated primarily for musculoskeletal pain conditions, are not representative of the population of the county where the clinic was located, and have worse health-related quality of life than that of the general population. Information about the characteristics of patients who use OMT is important for defining osteopathic distinctiveness and identifying potential areas for increasing the use of OMT. (ClinicalTrials.gov number NCT02395965). AN - 31790126 AU - Johnson, J. C. AU - Degenhardt, B. F. DA - Dec 1 DO - 10.7556/jaoa.2019.133 DP - NLM ET - 2019/12/04 IS - 12 KW - Adult Aged Female Humans Longitudinal Studies Male Manipulation, Osteopathic/*methods Middle Aged Musculoskeletal Diseases/*therapy Osteopathic Medicine/*organization & administration Pain Management/*methods Prospective Studies Quality of Life Surveys and Questionnaires LA - eng N1 - 1945-1997 Johnson, Jane C Degenhardt, Brian F Journal Article Observational Study United States J Am Osteopath Assoc. 2019 Dec 1;119(12):802-812. doi: 10.7556/jaoa.2019.133. PY - 2019 SN - 0098-6151 SP - 802-812 ST - Who Uses Osteopathic Manipulative Treatment? A Prospective, Observational Study Conducted by DO-Touch.NET T2 - J Am Osteopath Assoc TI - Who Uses Osteopathic Manipulative Treatment? A Prospective, Observational Study Conducted by DO-Touch.NET VL - 119 ID - 3791 ER - TY - JOUR AB - PURPOSE: Patients with low educational attainment may be at increased risk for unplanned health care utilization. This study aimed to determine what factors are related to emergency department (ED) visits in hopes of guiding treatments and early interventions. METHODS: At two medical centers in the Mid-Atlantic United States, 258 adults with sickle cell disease aged 19-70 years participated in a retrospective study where we examined whether education level is independently associated with ED visits after accounting for other socioeconomic status (SES) variables, such as pain and disease severity and psychosocial functioning. RESULTS: The data showed that patients without a high school education visited the ED three times as frequently as patients with post secondary education. Controlling for poverty and employment status decreased the effect of education on ED visits by 33.24 %. Further controlling for disease severity and/or psychosocial functioning could not account for the remaining association between education and ED visits, suggesting that education is independently associated with potentially avoidable emergency care. CONCLUSIONS: Early interventions addressing disparities in academic performance, especially for those children most at risk, may lead to improved long-term health outcomes in this population. AD - School of Medicine, University of Pittsburgh, 230 McKee Pl, Suite 600, Pittsburgh, PA, 15213, USA. jonassaintcr@upmc.edu. School of Medicine, Johns Hopkins University, Baltimore, MD, USA. Department of Psychology, University of Maryland, Baltimore County, Baltimore, USA. Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. School of Medicine, University of Pittsburgh, 230 McKee Pl, Suite 600, Pittsburgh, PA, 15213, USA. AN - 26818355 AU - Jonassaint, C. R. AU - Beach, M. C. AU - Haythornthwaite, J. A. AU - Bediako, S. M. AU - Diener-West, M. AU - Strouse, J. J. AU - Lanzkron, S. AU - Onojobi, G. AU - Carroll, C. P. AU - Haywood, C., Jr. DA - Jun DO - 10.1007/s12529-016-9538-y DP - NLM ET - 2016/01/29 IS - 3 KW - Adult Aged Anemia, Sickle Cell/*therapy Emergency Service, Hospital/*statistics & numerical data Employment Female Humans Male Middle Aged Pain/*etiology Patient Acceptance of Health Care/*statistics & numerical data Poverty Retrospective Studies Social Class Young Adult *Blood disorders *Chronic illness *Education *Emergency care *Health care utilization *Health disparities *Sickle cell disease *Socioeconomic status LA - eng N1 - 1532-7558 Jonassaint, C R Beach, M C Haythornthwaite, J A Bediako, S M Diener-West, M Strouse, J J Lanzkron, S Onojobi, G Carroll, C P Haywood, C Jr R01 HL088511/HL/NHLBI NIH HHS/United States K01 HL108832/HL/NHLBI NIH HHS/United States K12 HS022989/HS/AHRQ HHS/United States Journal Article Multicenter Study England Int J Behav Med. 2016 Jun;23(3):300-309. doi: 10.1007/s12529-016-9538-y. PY - 2016 SN - 1070-5503 SP - 300-309 ST - The Association between Educational Attainment and Patterns of Emergency Department Utilization among Adults with Sickle Cell Disease T2 - Int J Behav Med TI - The Association between Educational Attainment and Patterns of Emergency Department Utilization among Adults with Sickle Cell Disease VL - 23 ID - 4043 ER - TY - JOUR AB - Objective Map the current literature investigating autonomy development, identity development, and peer relationships in young people aged 10-24 years with chronic pain. Methods A scoping review method was used to systematically search four databases (APA PsycNET, PubMed, Web of Science, and Cinahl) for peer-reviewed articles. Search results were screened against inclusion and exclusion criteria to ensure they met the objective. Eligible papers were assessed for quality, their data relating to the objective were extracted, and results are synthesized. Results Searches returned 3,815 papers after the removal of duplicates, with 42 papers included in the full review. The majority of papers investigated peer relationships (86%). Fewer papers investigated autonomy (43%) and identity (21%) development. Included papers were mostly quantitative (64%), with fewer qualitative (34%) and mixed-methods papers (2%). Overall, we found bidirectional relationships between chronic pain in young people, their social development, and a range of functional outcomes. However, the mechanisms underlying these relationships remain relatively unexplored. Conclusions Review results are mapped onto the model proposed by Palermo et al. (2014). Guided by this model, clinical treatment for young people with chronic pain should consider social development. The model also sets out a future research agenda focused on exploring: (a) identity development, (b) the mechanisms underlying the relationships between social- developmental domains, pain, and outcomes, (c) a variety of participants and populations, and (d) a variety of methods, including longitudinal study designs. AN - WOS:000648966500011 AU - Jones, A. AU - Caes, L. AU - McMurtry, C. M. AU - Eccleston, C. AU - Jordan, A. DA - Mar DO - 10.1093/jpepsy/jsaa101 IS - 2 N1 - Jones, Abigail Caes, Line McMurtry, C. Meghan Eccleston, Christopher Jordan, Abbie Caes, Line/0000-0001-7355-0706; Jones, Abigail/0000-0001-9315-0857; Eccleston, Christopher/0000-0003-0698-1543; Jordan, Abbie/0000-0003-1595-5574 1465-735x PY - 2021 SN - 0146-8693 SP - 219-230 ST - Sociodevelopmental Challenges Faced by Young People with Chronic Pain: A Scoping Review T2 - Journal of Pediatric Psychology TI - Sociodevelopmental Challenges Faced by Young People with Chronic Pain: A Scoping Review UR - ://WOS:000648966500011 VL - 46 ID - 1750 ER - TY - JOUR AB - A simple study of migraine was undertaken in an industrial setting to identify facts about the condition of migraine which had previously been unrecorded in industry. The study was based on a definition of migraine encompassing headache accompanied by visual or gastro-intestinal disturbances. During the period from April 1979 to December 1979 there were 111 separate incidents reported to this department, with 281 working days lost in this period, which would give an average annual loss of 420 working days through migraine. Approximately 6% of the work-force were seen to be affected by migraine. Using a simple treatment it was possible to return the majority of the work-force to the place of work within 1 hour, with no subsequent problem caused to their health, either through migraine or accident. AN - 7418950 AU - Jones, A. AU - Harrop, C. DO - 10.1177/030006058000800503 DP - NLM ET - 1980/01/01 IS - 5 KW - Absenteeism Acetaminophen/therapeutic use Adolescent Adult England Female Humans Male Metoclopramide/therapeutic use Middle Aged Migraine Disorders/epidemiology/*therapy *Occupational Medicine Rest LA - eng N1 - Jones, A Harrop, C Journal Article England J Int Med Res. 1980;8(5):321-5. doi: 10.1177/030006058000800503. PY - 1980 SN - 0300-0605 (Print) 0300-0605 SP - 321-5 ST - Study of migraine and the treatment of acute attacks in industry T2 - J Int Med Res TI - Study of migraine and the treatment of acute attacks in industry VL - 8 ID - 3228 ER - TY - JOUR AB - The objective of this study was to analyse sociodemographic differences in medication use, health-care contacts and sickness absence among individuals with medication-overuse headache (MOH). A cross-sectional, population survey was conducted, in which 44,300 Swedes (≥15 years old) were interviewed over telephone. In total, 799 individuals had MOH. Of these, 47 % (n = 370) only used over-the-counter medications. During the last year, 46 % (n = 343) had made a headache-related visit to their physician and 14 % (n = 102) had visited a neurologist. Among individuals aged <30 years, the number of days/month with headache was greater than the number of days with medication use, whereas the opposite was true for those ≥30 years. Both the proportion using prophylactic medication and the proportion having consulted a neurologist were smaller among those who only had elementary school education than among those with higher education (p = 0.021 and p = 0.046). Those with a lower level of education also had a higher number of days/month with headache and with medication use than those with a higher educational level (p = 0.011 and p = 0.018). The MOH-sufferers have limited contacts with health-care and preventive measures thus need to include other actors as well. Particular efforts should be directed towards those with low educational levels, and more research on medication use in relation to age is required. AD - Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. Pernilla.Jonsson@socmed.gu.se AN - 22427000 AU - Jonsson, P. AU - Linde, M. AU - Hensing, G. AU - Hedenrud, T. C2 - PMC3356474 DA - Jun DO - 10.1007/s10194-012-0432-y DP - NLM ET - 2012/03/20 IS - 4 KW - Adolescent Adult Aged Analgesics/*adverse effects Analysis of Variance Community Health Planning Cross-Sectional Studies Delivery of Health Care/*statistics & numerical data Educational Status Female Headache Disorders, Secondary/*chemically induced/*epidemiology Humans Male Middle Aged Sick Leave/*statistics & numerical data Socioeconomic Factors Surveys and Questionnaires Sweden/epidemiology Young Adult LA - eng N1 - 1129-2377 Jonsson, Pernilla Linde, Mattias Hensing, Gunnel Hedenrud, Tove Journal Article Research Support, Non-U.S. Gov't J Headache Pain. 2012 Jun;13(4):281-90. doi: 10.1007/s10194-012-0432-y. Epub 2012 Mar 17. PY - 2012 SN - 1129-2369 (Print) 1129-2369 SP - 281-90 ST - Sociodemographic differences in medication use, health-care contacts and sickness absence among individuals with medication-overuse headache T2 - J Headache Pain TI - Sociodemographic differences in medication use, health-care contacts and sickness absence among individuals with medication-overuse headache VL - 13 ID - 3732 ER - TY - JOUR AB - STUDY DESIGN: Prospective, population-based cohort study. OBJECTIVES: To determine the prevalence of selected complications following traumatic spinal cord injury during acute care and to identify the risk factors for pressure ulcers. SETTING: The only tertiary academic (Groote Schuur) hospital in the catchment region providing specialised acute care. METHODS: A descriptive, observational study of an inception cohort. Secondary complications were predefined and consisted of pressure ulcers, pulmonary complications (pneumonia and atelectasis), urinary tract infections, autonomic dysreflexia, deep vein thrombosis, pulmonary embolism, postural hypotension, neuropathic pain and spasticity. Possible risk factors for pressure ulcers included variables concerning demographic and injury characteristics and complications. Both univariate and multivariate logistic regression analyses were used. RESULTS: Data of 141 patients (97%) were analysed. In total, 71 (50.3%) patients had one or more complication. The most common was pressure ulcers (n=42; 29.8%), followed by pulmonary complications (n=33; 23.4%) and urinary tract infections (n=24; 17%). Significant risk factors were gun-shot injury, motor completeness (American Spinal Injury Association Impairment Scale (AIS) A│B), vertebral injury, no spinal surgery, pulmonary complications, urinary tract infection and level of consciousness. In the final multivariate model that correctly predicted 81.6% of subjects, motor completeness and vertebral injury remained significant independent factors, whereas having a urinary tract infection was associated with an increased risk (odds ratio: 2.86), but not significant at the 5% level. CONCLUSION: Pressure ulcers and pulmonary complications were prevalent during specialised acute phase. The occurrence of pressure ulcers, despite protocols in place, is worrisome. To prevent pressure ulcers, special attention seems necessary for persons with motor complete lesions and those with vertebral injuries. AD - Karolinska Institutet, Department of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Stockholm, Sweden. AN - 26481710 AU - Joseph, C. AU - Nilsson Wikmar, L. DA - Jul DO - 10.1038/sc.2015.189 DP - NLM ET - 2015/10/21 IS - 7 KW - Adolescent Adult Age Factors Aged Aged, 80 and over Catchment Area, Health/statistics & numerical data Cohort Studies Community Health Planning Female Humans Logistic Models Male Middle Aged Nervous System Diseases/etiology Pressure Ulcer/*epidemiology/*etiology Prevalence Risk Factors South Africa/epidemiology Spinal Cord Injuries/*complications/*epidemiology Tuberculosis, Pulmonary/*epidemiology/*etiology Young Adult LA - eng N1 - 1476-5624 Joseph, C Nilsson Wikmar, L Journal Article Observational Study England Spinal Cord. 2016 Jul;54(7):535-9. doi: 10.1038/sc.2015.189. Epub 2015 Oct 20. PY - 2016 SN - 1362-4393 SP - 535-9 ST - Prevalence of secondary medical complications and risk factors for pressure ulcers after traumatic spinal cord injury during acute care in South Africa T2 - Spinal Cord TI - Prevalence of secondary medical complications and risk factors for pressure ulcers after traumatic spinal cord injury during acute care in South Africa VL - 54 ID - 4157 ER - TY - JOUR AB - Headaches are very common in school population. The aim of this study was to determine epidemiological data on headaches among Croatian schoolchildren and their connection to risk factors and other health complaints. In the study, we used the Croatian database of the international research entitled Health Behavior in School-aged Children for 2013/2014. It is a cross-sectional study conducted every four years in 44 countries among children aged 11-16. The students were interviewed using an anonymous standardized questionnaire. The Croatian sample consisted of 5741 students, of which 2857(49.8%) girls and 2884 (50.2%) boys. The response rate was 85.9%. Headaches were reported to be often (once a week to daily) by 23.5% of students and were more often in girls and in higher school grades. They were positively linked to cigarette smoking and health complaints such as back pain and stomachache, bad mood, nervousness, irritability, difficulties with sleeping and dizziness. Headaches are associated to many health problems and can cause difficulties in student functioning. This could be a serious problem. This study pointed to connection of headaches with cigarette smoking and importance to underpin the smoking prevention programs. AN - WOS:000461015100001 AU - Jurisic, I. AU - Simetin, I. P. AU - Dikanovic, M. AU - Cvitkovic, A. DA - Dec DO - 10.20471/acc.2018.57.04.01 IS - 4 N1 - Jurisic, Irena Simetin, Ivana Pavic Dikanovic, Marinko Cvitkovic, Ante 1333-9451 PY - 2018 SN - 0353-9466 SP - 613-617 ST - HEADACHES IN ADOLESCENTS - FREQUENCY, RISK FACTORS AND OTHER HEALTH COMPLAINTS: A CROSS-SECTIONAL STUDY IN CROATIA T2 - Acta Clinica Croatica TI - HEADACHES IN ADOLESCENTS - FREQUENCY, RISK FACTORS AND OTHER HEALTH COMPLAINTS: A CROSS-SECTIONAL STUDY IN CROATIA UR - ://WOS:000461015100001 VL - 57 ID - 1976 ER - TY - JOUR AB - The aim of the present study was to investigate the associations between parental chronic pain and anxiety, depression, and conduct problems in adolescents. The current study was based on cross-sectional surveys performed during 2006 to 2008 from the Nord Trøndelag Health Study (HUNT 3 and Young-HUNT 3). The sample consisted of 3227 adolescents aged 13 to 18 years for whom information was available on parental chronic pain and health statuses. Separate analyses were conducted for girls and boys. The results indicated that if both parents experienced chronic pain, there was an increased risk of symptoms of anxiety and depression in girls (OR=2.17, CI=1.36-3.45, P=.001) and boys (OR=2.33, CI=1.17-4.63, P=.016) compared with children for whom neither parent had chronic pain. Girls had an increased risk of conduct problems in school if their mothers had chronic pain (OR=1.33, CI=1.02-1.74, P=.034). These results remained after adjusting for the possible effects of confounding factors and parental mental health. The results suggest that the presence of both maternal and paternal chronic pain is a high risk factor for internalizing symptoms in both girls and boys. The present study offers insights that should prove useful in clinical work and further large-scale research. AD - Department of Neuroscience, Faculty of Medicine, The Regional Centre for Child and Adolescent Mental Health (RBUP), Norwegian University of Science and Technology, Trondheim, Norway Department of Child and Adolescent Psychiatry, St. Olav's University Hospital, Trondheim, Norway. AN - 22444189 AU - Kaasbøll, J. AU - Lydersen, S. AU - Indredavik, M. S. DA - May DO - 10.1016/j.pain.2012.02.013 DP - NLM ET - 2012/03/27 IS - 5 KW - Adolescent Adolescent Behavior/psychology Anxiety/*diagnosis/psychology Child of Impaired Parents/*psychology Chronic Pain/*psychology Depression/*diagnosis/psychology Female Health Status Health Surveys Humans Male Norway Sex Factors Surveys and Questionnaires LA - eng N1 - 1872-6623 Kaasbøll, Jannike Lydersen, Stian Indredavik, Marit S Journal Article Research Support, Non-U.S. Gov't United States Pain. 2012 May;153(5):1054-1062. doi: 10.1016/j.pain.2012.02.013. Epub 2012 Mar 21. PY - 2012 SN - 0304-3959 SP - 1054-1062 ST - Psychological symptoms in children of parents with chronic pain-the HUNT study T2 - Pain TI - Psychological symptoms in children of parents with chronic pain-the HUNT study VL - 153 ID - 3168 ER - TY - JOUR AB - ObjectiveThis retrospective chart review examined a mediation model of parent and family functioning, childhood depression, and functional disability in youth with chronic headaches. Specifically, we evaluated whether depression mediates the relations between protective parenting and functional disability and between family functioning and functional disability. BackgroundChildren and adolescents with chronic and recurrent headache report elevated symptoms of depression. Children with chronic pain conditions, including chronic headaches, have also been found to originate from families with greater conflict, poorer cohesion, and lower organizational structure, and impaired family functioning is associated with greater disability in youth with chronic pain. MethodsThree hundred and eighty-two patients ages 5-17 years who underwent a multidisciplinary evaluation at a tertiary pediatric headache clinic were included in this study. Participants completed a pain intensity rating, the Children's Depression Inventory, and the Functional Disability Inventory. A parent completed the Family Relationship Index and the Adult Responses to Children's Symptoms questionnaires. Structural equation modeling was used to examine a mediation model and several alternative models. ResultsMediation was not supported, but an alternative model with both direct and indirect pathways provided excellent fit to the data: 2(1)=0.745, P=.39; comparative fit index=1.00, root mean square error of approximation=0.00 (CI: 0.00-0.17). Family functioning (=-0.19, P<.01) and protective parenting (=0.17, P<.01) were associated with depression, but not disability. Depression was linked to disability (=0.24, P<.01). There was an indirect pathway from family functioning to depression to disability (=-0.05, P<.05). ConclusionsFamily context is an important variable to consider in youth with chronic headaches and disability. While many studies have identified family functioning and depressive symptoms as separately linked to functional impairment, to our knowledge, we are the first to demonstrate depression as an intermediary variable between family dysfunction and disability within the pediatric headache population. AN - WOS:000372891000005 AU - Kaczynski, K. AU - Gambhir, R. AU - Caruso, A. AU - Lebel, A. DA - Mar DO - 10.1111/head.12709 IS - 3 N1 - Kaczynski, Karen Gambhir, Rupa Caruso, Alessandra Lebel, Alyssa 1526-4610 PY - 2016 SN - 0017-8748 SP - 491-500 ST - Depression as a mediator of the relation between family functioning and functional disability in youth with chronic headaches T2 - Headache TI - Depression as a mediator of the relation between family functioning and functional disability in youth with chronic headaches UR - ://WOS:000372891000005 VL - 56 ID - 2180 ER - TY - JOUR AB - Objective:To assess characteristics of pain and gender differences and the impact of pain on daily living activities in Turkish schoolchildren who were admitted to health office with acute pain. Methods: This study was designed descriptive and study population included 467 (302 girls, 165 boys) schoolchildren in a public elementary school in Istanbul, Turkey. Data were collected using the Pain Assessment Form and Numerical Rating Scale by interviewing between September of 2007-the June of 2008. The Pain Assessment Form included questions regarding the localization, intensity, quality of the pain, pain related symptoms, the effects of pain on the daily living activities and socio-demographic questions. Results: Of the 1200 schoolchildren, 467 (39%) had admissions with pain to health office. Pain frequency in girls was significantly higher than that in boys in grade 4, 6 and total. The abdomen and head were most commonly cited as locations of pain. The mean pain intensity was 5.8(+/- 2.2). School children reported pain affected their concentration, social relations, physical activities and their sleep in a negative way. Conclusion: Our study provides a foundation for future studies to examine the incidence, characteristics, etiology and impact of pain in schoolchildren leading to the development of pain management programs at school. AN - WOS:000435245700007 AU - Kadioglu, H. AU - Ergun, A. AU - Yildiz, A. IS - 1 N1 - Kadioglu, Hasibe Ergun, Ayse Yildiz, Ayse Kadioglu, hasibe/X-9774-2019; Ergun, Ayse/X-5343-2019 Kadioglu, hasibe/0000-0003-4965-0277; Ergun, Ayse/0000-0003-3132-2005 PY - 2011 SN - 2459-1459 SP - 47-51 ST - Pain Characteristics of Turkish Schoolchildren T2 - Clinical and Experimental Health Sciences TI - Pain Characteristics of Turkish Schoolchildren UR - ://WOS:000435245700007 VL - 1 ID - 2515 ER - TY - JOUR AB - Much has been written about the recognition and treatment of acute pain, but the syndrome of chronic pain in the pediatric population has received little attention. A pediatrician faced with a child suffering from recurrent or chronic pain first should exclude an underlying organic illness. However, the clinician also should understand that recurrent painful episodes may lack an organic cause; they may be triggered by a variety of external and internal factors, particularly perceived stress. The consequences of the child's pain and its relief must be evaluated and viewed in the context of rewards, secondary gain, and parental anxiety. Chronic pain may influence self-esteem, socialization, and academic achievement, and these issues must be addressed. AD - Section of Pediatric Anesthesiology, Yale University School of Medicine, New Haven, CT, USA. AN - 7596918 AU - Kain, Z. N. AU - Rimar, S. DA - Jun DO - 10.1542/pir.16-6-218 DP - NLM ET - 1995/06/01 IS - 6 KW - Abdominal Pain Child Chronic Disease Headache Humans *Pain Management Pain Measurement LA - eng N1 - Kain, Z N Rimar, S Journal Article United States Pediatr Rev. 1995 Jun;16(6):218-22. doi: 10.1542/pir.16-6-218. PY - 1995 SN - 0191-9601 (Print) 0191-9601 SP - 218-22 ST - Management of chronic pain in children T2 - Pediatr Rev TI - Management of chronic pain in children VL - 16 ID - 3238 ER - TY - JOUR AB - Dysmenorrhea in the absence of pelvic abnormality is termed primary dysmenorrhea (PD). The health burden and social and economic costs of PD are high as it is reported to be the leading cause of recurrent absenteeism from school or work in adolescent girls and young adults. The belief that exercise works for relieving symptoms in women with PD is based on anecdotal evidence and non-experimental studies. There is very limited evidence from randomized controlled trials (RCTs) to support the use of exercise to reduce the intensity of menstrual pain. The objective of this study is to evaluate the effectiveness of exercise to reduce intensity of pain and improve quality of life in women with PD. We describe the study design of a single-blind (assessor), prospective, two-arm RCT, and the participant characteristics of the 70 women recruited in the age-group 18 to 43 years. The primary outcome of the study is pain intensity. The secondary outcomes of the study are quality of life, functional limitation, sleep, global improvement with treatment, and protocol adherence. The outcomes assessments are done at first menstrual period (baseline, Week 0), 2nd menstrual period (Week 4) and at two additional time points (Week 16 and Week 28) during the trial. The results of the study will provide physiotherapists, medical practitioners, and researchers as well as the women who have PD with new insights, knowledge, and evidence about the use of exercise to manage pain in women with PD. (C) 2015 Elsevier Inc. All rights reserved. AN - WOS:000357347800010 AU - Kannan, P. AU - Chapple, C. M. AU - Miller, D. AU - Claydon, L. S. AU - Baxter, G. D. DA - May DO - 10.1016/j.cct.2015.03.010 N1 - Kannan, Priya Chapple, Cathy M. Miller, Dawn Claydon, Leica S. Baxter, G. David Baxter, David/C-4027-2009 Baxter, David/0000-0003-2968-6950; Claydon, Leica/0000-0002-0428-3955; Chapple, Cathy/0000-0001-5141-8376; Kannan, Priya/0000-0003-2583-9614 1559-2030 PY - 2015 SN - 1551-7144 SP - 81-89 ST - Menstrual pain and quality of life in women with primary dysmenorrhea: Rationale, design, and interventions of a randomized controlled trial of effects of a treadmill-based exercise intervention T2 - Contemporary Clinical Trials TI - Menstrual pain and quality of life in women with primary dysmenorrhea: Rationale, design, and interventions of a randomized controlled trial of effects of a treadmill-based exercise intervention UR - ://WOS:000357347800010 VL - 42 ID - 2237 ER - TY - JOUR AB - Objectives Achieving good menstrual health and hygiene (MHH) is a public health challenge and there is little evidence to inform interventions. The aim of this study was to pilot test an intervention to improve MHH and school attendance in Uganda, in preparation for a future cluster-randomised trial. Design Longitudinal study with pre-post evaluation of a pilot intervention. Setting Two secondary schools in Entebbe, Uganda. Participants Of the 473 eligible students in secondary 2 (S2) at baseline, 450 (95.1%; 232 girls and 218 boys) consented/assented. 369 students (188 girls; 81.0%; and 181 boys; 83.0%) participated in the endline survey. Intervention The intervention comprised training teachers to improve delivery of government guidelines for puberty education, training in use of a menstrual kit and pain management, a drama skit, provision of analgesics and improvements to school water and sanitation hygiene facilities. Primary and secondary outcome measures Feasibility and acceptability of delivering the intervention. Baseline and endline quantitative surveys were conducted, with qualitative interviews conducted at endline. School attendance was assessed using self-completed daily diaries among a nested cohort of 100 female students. Results There were high levels of uptake of the individual and behavioural intervention components (puberty education, drama skit, menstrual hygiene management (MHM) kit and pain management). The proportion of girls reporting anxiety about next period decreased from 58.6% to 34.4%, and reported use of effective pain management increased from 76.4% to 91.4%. Most girls (81.4%) reported improved school toilet facilities, which improved their comfort managing menstruation. The diary data and qualitative data indicated a potential intervention impact on improving menstrual-related school absenteeism. Conclusions The pilot study showed that the multicomponent MHM intervention was acceptable and feasible to deliver, and potentially effective in improving menstruation knowledge and management. A cluster-randomised trial is needed to evaluate rigorously the intervention effects on MHM and school attendance. AN - WOS:000527786700031 AU - Kansiime, C. AU - Hytti, L. AU - Nalugya, R. AU - Nakuya, K. AU - Namirembe, P. AU - Nakalema, S. AU - Neema, S. AU - Tanton, C. AU - Alezuyo, C. AU - Musoke, S. N. AU - Torondel, B. AU - Francis, S. C. AU - Ross, D. A. AU - Bonell, C. AU - Seeley, J. AU - Weiss, H. A. C7 - e031182 DA - Feb DO - 10.1136/bmjopen-2019-031182 IS - 2 N1 - Kansiime, Catherine Hytti, Laura Nalugya, Ruth Nakuya, Kevin Namirembe, Prossy Nakalema, Shamirah Neema, Stella Tanton, Clare Alezuyo, Connie Musoke, Saidat Namuli Torondel, Belen Francis, Suzanna C. Ross, David A. Bonell, Christopher Seeley, Janet Weiss, Helen Anne Seeley, Janet/0000-0002-0583-5272; Francis, Suzanna Carter/0000-0002-3724-4813 PY - 2020 SN - 2044-6055 ST - Menstrual health intervention and school attendance in Uganda (MENISCUS-2): a pilot intervention study T2 - Bmj Open TI - Menstrual health intervention and school attendance in Uganda (MENISCUS-2): a pilot intervention study UR - ://WOS:000527786700031 VL - 10 ID - 1841 ER - TY - JOUR AB - The experimental study that follows was planned to determine the effectiveness of distraction on the pain level in school-age children as they underwent venipuncture. The study sample consisted of children between the ages of 7 and 12 years who underwent venipuncture at the Training and Research Hospital in Istanbul, Turkey between February and May 2012. A total of 144 children were conveniently sampled and evenly randomized into two groups of 72 children each. The primary instrument used to test children's pain level was the Faces Pain Scale-Revised (FPS-R). During the blood draw, the experimental group was given a kaleidoscope and told to look through it and describe what they saw, then rate their pain level on the FPS-R. Results showed that during venipuncture, the pain level of the control group was significantly higher (FPS-R = 3.27 ± 2.87) than the experimental group (FPS-R = 1.80 ± 1.84; p = .001) suggesting that distraction with a kaleidoscope is effective in reducing the pain children experience during venipuncture. AU - Karakaya, Ayfer AU - Gözen, Duygu DA - 2016/02// DO - 10.1016/j.pmn.2015.08.005 DP - PubMed IS - 1 J2 - Pain Manag Nurs KW - Adolescent Age Factors Child Female Humans Male Pain Pain Measurement Phlebotomy Play and Playthings Relaxation Therapy Sex Factors Socioeconomic Factors Turkey LA - eng PY - 2016 SN - 1532-8635 SP - 47-53 ST - The Effect of Distraction on Pain Level Felt by School-age Children During Venipuncture Procedure--Randomized Controlled Trial T2 - Pain Management Nursing: Official Journal of the American Society of Pain Management Nurses TI - The Effect of Distraction on Pain Level Felt by School-age Children During Venipuncture Procedure--Randomized Controlled Trial UR - http://www.ncbi.nlm.nih.gov/pubmed/26459008 VL - 17 ID - 85 ER - TY - JOUR AB - Objective To equip clinicians with recommendations specific to concerns related to the novel coronavirus disease 2019 (COVID-19), which impact the physical, emotional, and social health of youth with headache disorders. Background COVID-19 has affected societies on a global scale including children and youth with chronic headache disorders. Many concerns are predicted to arise in the 2020-2021 school year, whether classes are conducted in-person or virtually. Methods Clinical impressions were combined with a review of the literature, although limited due to the recent nature of this issue. Results We describe recommendations to support caregivers and youth as they face changes expected with the return to school in the fall of 2020. Conclusion Although there are significant concerns for caregivers and youth with migraine given the context of changes related to the pandemic, there are many recommendations that can help minimize exacerbations of the physical, emotional, and social health of youth with chronic migraine. AN - WOS:000603845000001 AU - Karvounides, D. AU - Marzouk, M. AU - Ross, A. C. AU - VanderPluym, J. H. AU - Pettet, C. AU - Ladak, A. AU - Ziplow, J. AU - Gentile, C. P. AU - Turner, S. AU - Anto, M. AU - Barmherzig, R. AU - Chadehumbe, M. AU - Kalkbrenner, J. AU - Malavolta, C. P. AU - Clementi, M. A. AU - Gerson, T. AU - Szperka, C. L. DA - Jan DO - 10.1111/head.14038 IS - 1 N1 - Karvounides, Dina Marzouk, Maya Ross, Alexandra C. VanderPluym, Juliana H. Pettet, Christina Ladak, Ali Ziplow, Jason Patterson Gentile, Carlyn Turner, Scott Anto, Marissa Barmherzig, Rebecca Chadehumbe, Madeline Kalkbrenner, Jocelyn Malavolta, Carrie P. Clementi, Michelle A. Gerson, Trevor Szperka, Christina L. Szperka, Christina/0000-0003-4786-8889; Patterson Gentile, Carlyn/0000-0003-4996-2457; Turner, Scott/0000-0002-1071-677X 1526-4610 PY - 2021 SN - 0017-8748 SP - 190-201 ST - The intersection of COVID-19, school, and headaches: Problems and solutions T2 - Headache TI - The intersection of COVID-19, school, and headaches: Problems and solutions UR - ://WOS:000603845000001 VL - 61 ID - 1775 ER - TY - JOUR AB - This review of the literature covers classification, epidemiology and clinical aspects of idiopathic headache in childhood and adolescence. In addition, pathogenetic models taking into account the complex involvement of organic, psychological and psychosocial factors are critically reviewed. A general pathogenetic model of migraine may be characterized by a given predisposition, various co-factors which enhance the tendency, and finally, trigger mechanisms which induce an attack. No generally accepted model exists for tension type headache. In assessing the importance of various factors thaught to be related to idiopathic headache, it is necessary to differentiate between causal relation, unspecific association, and coincidence. The aim of this review is to present potential factors influencing headache in childhood and adolescence and to discuss these factors critically with regard to their etiopathogenetic importance. Organic factors seem to be most important in migraine, whereas psychological and (psycho)social factors may influence any type of headache. Briefly, migraine in childhood and adolescence seems to be definitively associated with vegetative dysfunction, abdominal symptoms and hormonal factors and possibly with allergic reactions, whereas a relation to epilepsy can be excluded. There is absolutely no evidence for a typical personality of migraine patients. Various psychic reactions, however, are important in all types of headache. Depression and anxiety in young headache patients seem to be related generally to pain, but not specifically to headache. However, school problems, learning disabilities and stress coping behaviour seem to be related directly to recurrent headache. Additionally, there is evidence that the prevalence of headache is associated with low economic status. AN - WOS:A1993MM55300001 AU - Karwautz, A. AU - Woberbingol, C. AU - Wober, C. DA - Dec IS - 12 N1 - Karwautz, a woberbingol, c wober, c Wober, Christian/I-3574-2019 Wober, Christian/0000-0003-1382-1978; karwautz, andreas/0000-0001-9053-998X PY - 1993 SN - 0028-2804 SP - 753-765 ST - IDIOPATHIC HEADACHE IN CHILDHOOD AND ADOLESCENCE T2 - Nervenarzt TI - IDIOPATHIC HEADACHE IN CHILDHOOD AND ADOLESCENCE UR - ://WOS:A1993MM55300001 VL - 64 ID - 2950 ER - TY - JOUR AB - OBJECTIVE: Juvenile-onset fibromyalgia (JFM) is a chronic debilitating pain condition that negatively impacts physical, social and academic functioning. Cognitive-behavioral therapy (CBT) is beneficial in reducing functional disability among adolescents with JFM but has only a modest impact on pain reduction and does not improve physical exercise participation. This randomized controlled trial (RCT) aims to test whether a novel intervention that combines CBT with specialized neuromuscular exercise training (the Fibromyalgia Integrative Training program for Teens "FIT Teens") is superior to CBT alone or a graded aerobic exercise (GAE) program. DESIGN/METHODS: This 3-arm multi-site RCT will examine the efficacy of the FIT Teens intervention in reducing functional disability (primary outcome) and pain intensity (secondary outcome), relative to CBT or GAE. All interventions are 8-weeks (16 sessions) in duration and are delivered in small groups of 4-6 adolescents with JFM. A total of 420 participants are anticipated to be enrolled across seven sites with approximately equal allocation to each treatment arm. Functional disability and average pain intensity in the past week will be assessed at baseline, post-treatment and at 3-, 6-, 9- and 12-month follow-up. The 3-month follow-up is the primary endpoint to evaluate treatment efficacy; longitudinal assessments will determine maintenance of treatment gains. Changes in coping, fear of movement, biomechanical changes and physical fitness will also be evaluated. CONCLUSIONS: This multi-site RCT is designed to evaluate whether the combined FIT Teens intervention will have significantly greater effects on disability and pain reduction than CBT or GAE alone for youth with JFM. Clinical trials.gov registration: NCT03268421. AD - Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, OH, USA; Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. Electronic address: susmita.kashikar-zuck@cchmc.org. Sports Medicine Research Institute, and Department of Orthopaedics, The Ohio State University Wexner Medical Center, Columbus, OH, USA. Department of Pediatric Medicine, Sidra Medicine, Doha, Qatar; Weill Cornell Medicine, Doha, Qatar. Division of Developmental and Behavioral Sciences, Children's Mercy Hospital, Kansas City, KS, USA. Department of Pediatrics, University of Louisville, School of Medicine, Norton Children's Hospital, Louisville, KY, USA. Department of Pediatrics and Nursing, University of Connecticut, Hartford, CT, USA. Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, OH, USA; Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. Division of Pain Medicine, Department of Anesthesia, Boston Children's Hospital, Boston, MA, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, USA. Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, OH, USA; Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. Sports Performance and Research Center, Emory University School of Medicine, Atlanta, GA, USA. Center for Motion Analysis, Connecticut Children's Medical Center, Department of Orthopedic Surgery, University of Connecticut School of Medicine, Hartford, CT, USA. Sport Sciences, Waseda University, Tokyo, Japan; The Micheli Center for Sports Injury Prevention, Waltham, MA, USA. Child Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, Toronto, Canada; Lawrence S. Bloomberg Faculty of Nursing, University of Toronto, Toronto, Canada. Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, OH, USA; Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. Division of Sports Medicine, SPORT Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. Department of Pediatrics and Nursing, University of Connecticut, Hartford, CT, USA; Division of Pain and Palliative Medicine, Connecticut Children's Medical Center, Hartford, CT, USA. AN - 33618033 AU - Kashikar-Zuck, S. AU - Briggs, M. S. AU - Bout-Tabaku, S. AU - Connelly, M. AU - Daffin, M. AU - Guite, J. AU - Ittenbach, R. AU - Logan, D. E. AU - Lynch-Jordan, A. M. AU - Myer, G. D. AU - Ounpuu, S. AU - Peugh, J. AU - Schikler, K. AU - Sugimoto, D. AU - Stinson, J. N. AU - Ting, T. V. AU - Thomas, S. AU - Williams, S. E. AU - Zempsky, W. C2 - PMC8089039 C6 - NIHMS1677964 DA - Apr DO - 10.1016/j.cct.2021.106321 DP - NLM ET - 2021/02/23 KW - Cognitive behavioral therapy Juvenile fibromyalgia Neuromuscular training Pediatric chronic pain RCT- randomized clinical trial interests or personal relationships related to the work reported in this paper. Declaration of interests The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. LA - eng N1 - 1559-2030 Kashikar-Zuck, Susmita Briggs, Matthew S Bout-Tabaku, Sharon Connelly, Mark Daffin, Morgan Guite, Jessica Ittenbach, Richard Logan, Deirdre E Lynch-Jordan, Anne M Myer, Gregory D Ounpuu, Sylvia Peugh, James Schikler, Kenneth Sugimoto, Dai Stinson, Jennifer N Ting, Tracy V Thomas, Staci Williams, Sara E Zempsky, William Childhood Arthritis and Rheumatology Research Alliance (CARRA) Pain Workgroup Investigators R01 AR070474/AR/NIAMS NIH HHS/United States U34 AR067978/AR/NIAMS NIH HHS/United States Journal Article Contemp Clin Trials. 2021 Apr;103:106321. doi: 10.1016/j.cct.2021.106321. Epub 2021 Feb 20. PY - 2021 SN - 1551-7144 (Print) 1551-7144 SP - 106321 ST - Randomized clinical trial of Fibromyalgia Integrative Training (FIT teens) for adolescents with juvenile fibromyalgia - Study design and protocol T2 - Contemp Clin Trials TI - Randomized clinical trial of Fibromyalgia Integrative Training (FIT teens) for adolescents with juvenile fibromyalgia - Study design and protocol VL - 103 ID - 3994 ER - TY - JOUR AB - Objective: Juvenile-onset fibromyalgia (JFM) is a chronic debilitating pain condition that negatively impacts physical, social and academic functioning. Cognitive-behavioral therapy (CBT) is beneficial in reducing functional disability among adolescents with JFM but has only a modest impact on pain reduction and does not improve physical exercise participation. This randomized controlled trial (RCT) aims to test whether a novel intervention that combines CBT with specialized neuromuscular exercise training (the Fibromyalgia Integrative Training program for Teens ?FIT Teens?) is superior to CBT alone or a graded aerobic exercise (GAE) program. Design/Methods: This 3-arm multi-site RCT will examine the efficacy of the FIT Teens intervention in reducing functional disability (primary outcome) and pain intensity (secondary outcome), relative to CBT or GAE. All interventions are 8-weeks (16 sessions) in duration and are delivered in small groups of 4?6 adolescents with JFM. A total of 420 participants are anticipated to be enrolled across seven sites with approximately equal allocation to each treatment arm. Functional disability and average pain intensity in the past week will be assessed at baseline, post-treatment and at 3-, 6-, 9- and 12-month follow-up. The 3-month follow-up is the primary endpoint to evaluate treatment efficacy; longitudinal assessments will determine maintenance of treatment gains. Changes in coping, fear of movement, biomechanical changes and physical fitness will also be evaluated. AN - WOS:000645089200004 AU - Kashikar-Zuck, S. AU - Briggs, M. S. AU - Bout-Tabaku, S. AU - Connelly, M. AU - Daffin, M. AU - Guite, J. AU - Ittenbach, R. AU - Logan, D. E. AU - Lynch-Jordan, A. M. AU - Myer, G. D. AU - Ounpuu, S. AU - Peugh, J. AU - Schikler, K. AU - Sugimoto, D. AU - Stinson, J. N. AU - Ting, T. V. AU - Thomas, S. AU - Williams, S. E. AU - Zempsky, W. AU - Childhood Arthrit Rheumatology, Res C7 - 106321 DA - Apr DO - 10.1016/j.cct.2021.106321 N1 - Kashikar-Zuck, Susmita Briggs, Matthew S. Bout-Tabaku, Sharon Connelly, Mark Daffin, Morgan Guite, Jessica Ittenbach, Richard Logan, Deirdre E. Lynch-Jordan, Anne M. Myer, Gregory D. Ounpuu, Sylvia Peugh, James Schikler, Kenneth Sugimoto, Dai Stinson, Jennifer N. Ting, Tracy, V Thomas, Staci Williams, Sara E. Zempsky, William 1559-2030 PY - 2021 SN - 1551-7144 ST - Randomized clinical trial of Fibromyalgia Integrative Training (FIT teens) for adolescents with juvenile fibromyalgia ? Study design and protocol T2 - Contemporary Clinical Trials TI - Randomized clinical trial of Fibromyalgia Integrative Training (FIT teens) for adolescents with juvenile fibromyalgia ? Study design and protocol UR - ://WOS:000645089200004 VL - 103 ID - 1743 ER - TY - JOUR AB - Objective. To assess peer relationships of adolescents with juvenile primary fibromyalgia syndrome (JPFS) compared with matched classroom comparison peers (MCCPs) without a chronic illness. JPFS is characterized by chronic musculoskeletal pain, sleep disturbance, fatigue, and difficulty with daily functioning. Adolescents with JPFS often report problems with school and participating in peer activities, placing them at risk for social isolation from their peers and psychosocial adjustment problems. Methods. Participants were 55 adolescents with JPFS (ages 12-18 years) from a pediatric outpatient rheumatology clinic and 55 MCCPs. Data on peer reputation and peer acceptance were collected from teachers, peers, and self report in a classroom setting with no focus on JPFS. Results. Adolescents with JPFS were perceived (by peer and self reports) as being more isolated and withdrawn and less popular. Adolescents with JPFS were less well liked, were selected less often as a best friend, and had fewer reciprocated friendships. Conclusion. Our findings suggest that adolescents with JPFS are experiencing problems with peer relationships. Given the central role that peer relationships play in psychological development of children, and because peer rejection and isolation have been associated with subsequent adjustment problems, these findings are concerning. Longitudinal studies of adolescents with JPFS are needed to ascertain whether these patients are at long-term risk and will provide a foundation for the need for early interventions. Results are discussed within the context of earlier findings for other adolescents with chronic illness and rheumatic conditions, such as juvenile idiopathic arthritis, who demonstrated no social problems. AN - WOS:000245878200016 AU - Kashikar-Zuck, S. AU - Lynch, A. M. AU - Graham, T. B. AU - Swain, N. F. AU - Mullen, S. M. AU - Noll, R. B. DA - Apr DO - 10.1002/art.22615 IS - 3 N1 - Kashikar-Zuck, Susmita Lynch, Anne M. Graham, T. Brent Swain, Nicole F. Mullen, Sara M. Noll, Robert B. PY - 2007 SN - 0004-3591 SP - 474-480 ST - Social functioning and peer relationships of adolescents with juvenile fibromyalgia syndrome T2 - Arthritis & Rheumatism-Arthritis Care & Research TI - Social functioning and peer relationships of adolescents with juvenile fibromyalgia syndrome UR - ://WOS:000245878200016 VL - 57 ID - 2692 ER - TY - JOUR AB - Background: Mood and anxiety disorders are common psychiatric conditions among adult patients with fibromyalgia syndrome, but little is known about whether psychiatric disorders are prevalent among pediatric patients with fibromyalgia. Objective: The primary objective of this study was to assess the prevalence of mood, anxiety, and behavioral disorders in a clinical sample of children and adolescents with juvenile primary fibromyalgia syndrome (JPFS) and assess the relationship between psychiatric disorders and JPFS symptom severity. Methods: Standardized psychiatric interviews were conducted with children and their parents/primary caregivers, and measures of symptom severity including pain intensity and physician global ratings were obtained for 76 children and adolescents diagnosed with JPFS (ages 11 to 18 y) in pediatric rheumatology clinics at 4 hospitals in the Midwest. Results: A total of 67.1 % of patients had at least 1 current and 71.5% had at least 1 lifetime DSM-IV (Diagnostic and Statistical Manual of Mental Disorders-fourth edition) psychiatric diagnosis. The most frequent psychiatric diagnosis was anxiety disorder (57.5% of JPFS patients). Although mood difficulties were also common, the presence of major depression was lower than has been reported for adults with fibromyalgia syndrome. Physicians' global assessment of functioning was significantly lower for patients with a current anxiety disorder. There were no significant differences in pain severity among patients with and without anxiety.. mood, or behavioral disorders. Discussion: There seems to be a high prevalence of anxiety disorders in patients with JPFS, and presence of anxiety disorder is associated with poorer physician-rated functioning. Future research should explore whether early anxiety symptoms are predictive of long-term functioning. AN - WOS:000259662200009 AU - Kashikar-Zuck, S. AU - Parkins, I. S. AU - Graham, T. B. AU - Lynch, A. M. AU - Passo, M. AU - Johnston, M. AU - Schikler, K. N. AU - Hashkes, P. J. AU - Banez, G. AU - Richards, M. M. DA - Sep DO - 10.1097/AJP.0b013e31816d7d23 IS - 7 N1 - Kashikar-Zuck, Susmita Parkins, Irina S. Graham, Thomas Brent Lynch, Anne M. Passo, Murray Johnston, Megan Schikler, Kenneth N. Hashkes, Philip J. Banez, Gerard Richards, Margaret M. PY - 2008 SN - 0749-8047 SP - 620-626 ST - Anxiety, mood, and behavioral disorders among pediatric patients with juvenile fibromyalgia syndrome T2 - Clinical Journal of Pain TI - Anxiety, mood, and behavioral disorders among pediatric patients with juvenile fibromyalgia syndrome UR - ://WOS:000259662200009 VL - 24 ID - 2637 ER - TY - JOUR AB - OBJECTIVE: To evaluate the performance and score interpretability of the Headache Impact Test (HIT-6) questionnaire in a headache patient population. BACKGROUND: The HIT-6 is a standardized questionnaire designed to assess headache-related disability. Norms have been established using randomly sampled respondents from the general population. This study evaluated the psychometric properties of the HIT-6 scale among new adult patients who presented for treatment at a university headache-specialty practice. METHODS: Participants were 309 new patients who presented for treatment at a headache-specialty clinic in an academic medical center. RESULTS: Respondents ranged in age from 18 to 91 years, with an average age of 41 years (SD = 13 years) and were predominantly female (77%). Over half (57%) experienced chronic daily headache. Scores ranged from 38 to 78, with an average of 65.6 (SD = 7.0) and the majority (87%) had "severe impact" (60 or higher). The scale showed high reliability (alpha= 0.87) and an exploratory factor analysis showed large loadings from |0.57| to |0.86| and suggested a single disability factor. Scores were moderately negatively correlated with Short Form Health Survey (SF-36) subscales, ranging from -0.22 for mental health to -0.57 for social functioning. Item response theory analyses showed that half of the items functioned well across the disability continuum, while the remaining items discriminated between low and high levels of headache impact. CONCLUSIONS: These findings suggest that the HIT-6 is useful for assessing headache-related disability among patients who seek headache-specialty care. AD - Department of Psychology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. AN - 15953295 AU - Kawata, A. K. AU - Coeytaux, R. R. AU - Devellis, R. F. AU - Finkel, A. G. AU - Mann, J. D. AU - Kahn, K. DA - Jun DO - 10.1111/j.1526-4610.2005.05130.x DP - NLM ET - 2005/06/15 IS - 6 KW - Adolescent Adult Aged Aged, 80 and over Female Headache/*physiopathology Humans Male Middle Aged Pain Clinics Psychometrics/*instrumentation Reproducibility of Results *Sickness Impact Profile Surveys and Questionnaires/*standards LA - eng N1 - Kawata, Ariane K Coeytaux, Remy R Devellis, Robert F Finkel, Alan G Mann, J Douglas Kahn, Kevin Journal Article Research Support, Non-U.S. Gov't Validation Study United States Headache. 2005 Jun;45(6):638-43. doi: 10.1111/j.1526-4610.2005.05130.x. PY - 2005 SN - 0017-8748 (Print) 0017-8748 SP - 638-43 ST - Psychometric properties of the HIT-6 among patients in a headache-specialty practice T2 - Headache TI - Psychometric properties of the HIT-6 among patients in a headache-specialty practice VL - 45 ID - 3594 ER - TY - JOUR AB - The study sought to characterize back pain (BP) (in the period of 12 months) in children and youth aged 10 to 19 from eastern Poland.The study included 11619 children and youth (6254 girls and 5365 boys) aged 10 to 19 from eastern Poland. An original questionnaire was applied as a research tool. Before the study, the reliability of the questionnaire had been assessed. The Kappa coefficient value for all the analyzed variables was equal to or higher than 0.91.Over 74.4% of the respondents admitted that within the last 12 months, they had experienced BP which was usually located in the lumbar spine (55.8%). The percentage of individuals reporting BP increased with age of participants. Girls reported BP more often than boys (82.8% vs 64.3%). The main circumstances in which BP occurred included lifting heavy objects, carrying school backpack and maintaining a sedentary position (70.7% vs 67.4% vs 67.8%). Over 67% of the respondents declared they did not know ergonomic principles.High prevalence of BP was noted. The declared BP was mainly located in the lumbar spine. Girls reported BP more often than boys. The students presented a very low level of knowledge about ergonomics. Therefore, the appropriate education should be included at school. AU - Kędra, Agnieszka AU - Kolwicz-Gańko, Aleksandra AU - Sitarski, Dominik AU - Kędra, Przemysław AU - Czaprowski, Dariusz DA - 2019/05// DO - 10.1097/MD.0000000000015729 DP - PubMed IS - 22 J2 - Medicine (Baltimore) KW - Adolescent Back Pain Child Cohort Studies Female Health Behavior Health Knowledge, Attitudes, Practice Humans Lumbar Vertebrae Male Poland Prevalence Schools Students Surveys and Questionnaires Young Adult LA - eng PY - 2019 SN - 1536-5964 SP - e15729 ST - Prevalence of back pain and the knowledge of preventive measures in a cohort of 11619 Polish school-age children and youth-an epidemiological study T2 - Medicine TI - Prevalence of back pain and the knowledge of preventive measures in a cohort of 11619 Polish school-age children and youth-an epidemiological study UR - http://www.ncbi.nlm.nih.gov/pubmed/31145287 VL - 98 ID - 61 ER - TY - JOUR AB - The prevention of pain in neonates should be the goal of all pediatricians and health care professionals who work with neonates, not only because it is ethical but also because repeated painful exposures have the potential for deleterious consequences. Neonates at greatest risk of neurodevelopmental impairment as a result of preterm birth (ie, the smallest and sickest) are also those most likely to be exposed to the greatest number of painful stimuli in the NICU. Although there are major gaps in knowledge regarding the most effective way to prevent and relieve pain in neonates, proven and safe therapies are currently underused for routine minor, yet painful procedures. Therefore, every health care facility caring for neonates should implement (1) a pain-prevention program that includes strategies for minimizing the number of painful procedures performed and (2) a pain assessment and management plan that includes routine assessment of pain, pharmacologic and nonpharmacologic therapies for the prevention of pain associated with routine minor procedures, and measures for minimizing pain associated with surgery and other major procedures. AN - WOS:000371392000061 AU - Keels, E. AU - Sethna, N. AU - Watterberg, K. L. AU - Cummings, J. J. AU - Benitz, W. E. AU - Eichenwald, E. C. AU - Poindexter, B. B. AU - Stewart, D. L. AU - Aucott, S. W. AU - Goldsmith, J. P. AU - Puopolo, K. M. AU - Wang, K. S. AU - Tobias, J. D. AU - Agarwal, R. AU - Anderson, C. T. M. AU - Hardy, C. A. AU - Honkanen, A. AU - Rehman, M. A. AU - Bannister, C. F. AU - Comm Fetus, Newborn AU - Sect Anesthesiology Pain, Med C7 - e20154271 DA - Feb DO - 10.1542/peds.2015-4271 IS - 2 N1 - Keels, Erin Sethna, Navil Watterberg, Kristi L. Cummings, James J. Benitz, William E. Eichenwald, Eric C. Poindexter, Brenda B. Stewart, Dan L. Aucott, Susan W. Goldsmith, Jay P. Puopolo, Karen M. Wang, Kasper S. Tobias, Joseph D. Agarwal, Rita Anderson, Corrie T. M. Hardy, Courtney A. Honkanen, Anita Rehman, Mohamed A. Bannister, Carolyn F. Stewart, Dan/R-7130-2019; Agarwal, Rita/AAB-2378-2020 1098-4275 PY - 2016 SN - 0031-4005 ST - Prevention and Management of Procedural Pain in the Neonate: An Update T2 - Pediatrics TI - Prevention and Management of Procedural Pain in the Neonate: An Update UR - ://WOS:000371392000061 VL - 137 ID - 2187 ER - TY - JOUR AB - This systematic review summarizes a literature review and consensus process among a multidisciplinary team of health care experts and leaders to generate evidence-based opioid prescribing guidelines for children who require surgery. Question What are the risks of opioid misuse in children and adolescents, what nonopioid regimens effectively manage pain in children after surgery, and what education on opioid use should be provided to families? Findings In this expert panel review and opinion, opioid misuse was found to occur frequently, particularly for adolescents with access to opioids, and nonopioid regimens were found to be effective to minimize or eliminate need for opioids after surgery. Families of children who undergo surgery want instruction on pain management before and after surgery. Meaning Health care workers caring for children after surgery should recognize the risks of opioids, maximize nonopioid regimens, and educate families appropriately. Importance Opioids are frequently prescribed to children and adolescents after surgery. Prescription opioid misuse is associated with high-risk behavior in youth. Evidence-based guidelines for opioid prescribing practices in children are lacking. Objective To assemble a multidisciplinary team of health care experts and leaders in opioid stewardship, review current literature regarding opioid use and risks unique to pediatric populations, and develop a broad framework for evidence-based opioid prescribing guidelines for children who require surgery. Evidence Review Reviews of relevant literature were performed including all English-language articles published from January 1, 1988, to February 28, 2019, found via searches of the PubMed (MEDLINE), CINAHL, Embase, and Cochrane databases. Pediatric was defined as children younger than 18 years. Animal and experimental studies, case reports, review articles, and editorials were excluded. Selected articles were graded using tools from the Oxford Centre for Evidence-based Medicine 2011 levels of evidence. The Appraisal of Guidelines for Research & Evaluation (AGREE) II instrument was applied throughout guideline creation. Consensus was determined using a modified Delphi technique. Findings Overall, 144 articles were screened for inclusion, with 217 unique articles included for qualitative synthesis. Twenty guideline statements were generated from a 2-day in-person meeting and subsequently reviewed, edited, and endorsed externally by pediatric surgical specialists, the American Pediatric Surgery Association Board of Governors, the American Academy of Pediatrics Section on Surgery Executive Committee, and the American College of Surgeons Board of Regents. Review of the literature and guideline statements underscored 3 primary themes: (1) health care professionals caring for children who require surgery must recognize the risks of opioid misuse associated with prescription opioids, (2) nonopioid analgesic use should be optimized in the perioperative period, and (3) patient and family education regarding perioperative pain management and safe opioid use practices must occur both before and after surgery. Conclusions and Relevance These are the first opioid-prescribing guidelines to address the unique needs of children who require surgery. Health care professionals caring for children and adolescents in the perioperative period should optimize pain management and minimize risks associated with opioid use by engaging patients and families in opioid stewardship efforts. AN - WOS:000592281200009 AU - Kelley-Quon, L. I. AU - Kirkpatrick, M. G. AU - Ricca, R. L. AU - Baird, R. AU - Harbaugh, C. M. AU - Brady, A. AU - Garrett, P. AU - Wills, H. AU - Argo, J. AU - Diefenbach, K. A. AU - Henry, M. C. W. AU - Sola, J. E. AU - Mahdi, E. M. AU - Goldin, A. B. AU - St Peter, S. D. AU - Downard, C. D. AU - Azarow, K. S. AU - Shields, T. AU - Kim, E. DO - 10.1001/jamasurg.2020.5045 N1 - Kelley-Quon, Lorraine I. Kirkpatrick, Matthew G. Ricca, Robert L. Baird, Robert Harbaugh, Calista M. Brady, Ashley Garrett, Paula Wills, Hale Argo, Jonathan Diefenbach, Karen A. Henry, Marion C. W. Sola, Juan E. Mahdi, Elaa M. Goldin, Adam B. St Peter, Shawn D. Downard, Cynthia D. Azarow, Kenneth S. Shields, Tracy Kim, Eugene Baird, Robert/0000-0002-2013-1150; Shields, Tracy/0000-0001-5670-7388 2168-6262 SN - 2168-6254 ST - Guidelines for Opioid Prescribing in Children and Adolescents After Surgery An Expert Panel Opinion T2 - Jama Surgery TI - Guidelines for Opioid Prescribing in Children and Adolescents After Surgery An Expert Panel Opinion UR - ://WOS:000592281200009 ID - 1785 ER - TY - JOUR AB - Importance Opioids are frequently prescribed to children and adolescents after surgery. Prescription opioid misuse is associated with high-risk behavior in youth. Evidence-based guidelines for opioid prescribing practices in children are lacking. Objective To assemble a multidisciplinary team of health care experts and leaders in opioid stewardship, review current literature regarding opioid use and risks unique to pediatric populations, and develop a broad framework for evidence-based opioid prescribing guidelines for children who require surgery. Evidence Review Reviews of relevant literature were performed including all English-language articles published from January 1, 1988, to February 28, 2019, found via searches of the PubMed (MEDLINE), CINAHL, Embase, and Cochrane databases. Pediatric was defined as children younger than 18 years. Animal and experimental studies, case reports, review articles, and editorials were excluded. Selected articles were graded using tools from the Oxford Centre for Evidence-based Medicine 2011 levels of evidence. The Appraisal of Guidelines for Research & Evaluation (AGREE) II instrument was applied throughout guideline creation. Consensus was determined using a modified Delphi technique. Findings Overall, 14 574 articles were screened for inclusion, with 217 unique articles included for qualitative synthesis. Twenty guideline statements were generated from a 2-day in-person meeting and subsequently reviewed, edited, and endorsed externally by pediatric surgical specialists, the American Pediatric Surgery Association Board of Governors, the American Academy of Pediatrics Section on Surgery Executive Committee, and the American College of Surgeons Board of Regents. Review of the literature and guideline statements underscored 3 primary themes: (1) health care professionals caring for children who require surgery must recognize the risks of opioid misuse associated with prescription opioids, (2) nonopioid analgesic use should be optimized in the perioperative period, and (3) patient and family education regarding perioperative pain management and safe opioid use practices must occur both before and after surgery. Conclusions and Relevance These are the first opioid-prescribing guidelines to address the unique needs of children who require surgery. Health care professionals caring for children and adolescents in the perioperative period should optimize pain management and minimize risks associated with opioid use by engaging patients and families in opioid stewardship efforts. Question What are the risks of opioid misuse in children and adolescents, what nonopioid regimens effectively manage pain in children after surgery, and what education on opioid use should be provided to families? Findings In this expert panel review and opinion, opioid misuse was found to occur frequently, particularly for adolescents with access to opioids, and nonopioid regimens were found to be effective to minimize or eliminate need for opioids after surgery. Families of children who undergo surgery want instruction on pain management before and after surgery. Meaning Health care workers caring for children after surgery should recognize the risks of opioids, maximize nonopioid regimens, and educate families appropriately. This systematic review summarizes a literature review and consensus process among a multidisciplinary team of health care experts and leaders to generate evidence-based opioid prescribing guidelines for children who require surgery. AN - WOS:000607875800011 AU - Kelley-Quon, L. I. AU - Kirkpatrick, M. G. AU - Ricca, R. L. AU - Baird, R. AU - Harbaugh, C. M. AU - Brady, A. AU - Garrett, P. AU - Wills, H. AU - Argo, J. AU - Diefenbach, K. A. AU - Henry, M. C. W. AU - Sola, J. E. AU - Mahdi, E. M. AU - Goldin, A. B. AU - St Peter, S. D. AU - Downard, C. D. AU - Azarow, K. S. AU - Shields, T. AU - Kim, E. DA - Jan DO - 10.1001/jamasurg.2020.504511,2020. IS - 1 N1 - Kelley-Quon, Lorraine I. Kirkpatrick, Matthew G. Ricca, Robert L. Baird, Robert Harbaugh, Calista M. Brady, Ashley Garrett, Paula Wills, Hale Argo, Jonathan Diefenbach, Karen A. Henry, Marion C. W. Sola, Juan E. Mahdi, Elaa M. Goldin, Adam B. St Peter, Shawn D. Downard, Cynthia D. Azarow, Kenneth S. Shields, Tracy Kim, Eugene Baird, Robert/0000-0002-2013-1150; Shields, Tracy/0000-0001-5670-7388 2168-6262 PY - 2021 SN - 2168-6254 SP - 76-90 ST - Guidelines for Opioid Prescribing in Children and Adolescents After Surgery An Expert Panel Opinion T2 - Jama Surgery TI - Guidelines for Opioid Prescribing in Children and Adolescents After Surgery An Expert Panel Opinion UR - ://WOS:000607875800011 VL - 156 ID - 1773 ER - TY - JOUR AB - BACKGROUND: Our aim was to describe the relationship between risk factors, such as stress, depression, and anxiety, and potentially protective factors against pediatric headache-related disability, such as mindfulness, resilience, and self-compassion, and to determine teens' interest in mind-body skills training to help reduce headache-related disability. METHODS: This was a cross-sectional survey among adolescents seen in an academic neurology clinic reporting four or more headaches monthly using standardized instruments to determine the relationship between putative risk and protective factors as well as physiologic markers of inflammation and vagal tone and headache-related disability. RESULTS: Among the 29 participants, 31% were male, the average age was 14.8 years, average headache frequency was 11.6 per month, and the most commonly reported trigger was stress (86%). The only risk or protective factor significantly associated with headache-related disability was depression (r = 0.52, P = 0.004). Depression was negatively correlated with mindfulness, resilience, and self-compassion (P < 0.01 each) and positively correlated with stress, sleep disturbance, and anxiety (P < 0.01 each). Biomarkers of vagal tone and inflammation were correlated with each other but not with headache-related disability or depression. There was strong interest in learning skills like slow, deep breathing practices supported by a smart phone application to reduce stress and the negative impact of headaches on daily life. DISCUSSION: Among teens with frequent migraine headaches, depression is the strongest risk factor for headache-related disability. Stress is viewed as a headache trigger, and teens reported wanting to learn simple stress management strategies supported by a smart phone application to help reduce headache-related disability. AN - WOS:000372683400011 AU - Kemper, K. J. AU - Heyer, G. AU - Pakalnis, A. AU - Binkley, P. F. DA - Mar DO - 10.1016/j.pediatrneurol.2015.10.024 N1 - Kemper, Kathi J. Heyer, Geoffrey Pakalnis, Ann Binkley, Philip F. Heyer, Geoffrey/0000-0001-9334-3739 1873-5150 PY - 2016 SN - 0887-8994 SP - 48-54 ST - What Factors Contribute to Headache-Related Disability in Teens? T2 - Pediatric Neurology TI - What Factors Contribute to Headache-Related Disability in Teens? UR - ://WOS:000372683400011 VL - 56 ID - 2181 ER - TY - JOUR AB - OBJECTIVE: To determine whether patient-reported measures would be clinically sensitive and useful for identifying functional change within an intensive chronic pain program setting by examining 2 patient-reported measures administered as part of physical and occupational therapy for chronic pain. DESIGN: A retrospective data analysis of children and adolescents with chronic pain treated over a single calendar year. Paired t tests evaluated change in perceived function measures and pain over time. Standardized residual change scores were used in subsequent regression to assess associations between change scores. SETTING: An interdisciplinary pediatric pain rehabilitation program that supports children and adolescents with chronic pain by increasing strength, flexibility, and endurance; facilitating a return to daily life activities; and using appropriate self-directed coping and pain management skills. PARTICIPANTS: Children and adolescents (N=109; age range, 8-19y; 83% girls) with various chronic pain diagnoses who were admitted to a 3- to 4-week intensive pain rehabilitation program. INTERVENTIONS: Participants were involved in physical and occupational therapy for 3 hours daily, as well as recreation therapy, psychology, school, aquatics, art therapy, and music therapy for a total of 8 hours daily. Parents were involved in parent education with therapists from all disciplines in conjunction with their child's programming. MAIN OUTCOME MEASURES: Lower Extremity Functional Scale (LEFS), Upper Extremity Functional Index (UEFI), and self-reported pain severity rating on 0-to-10 numerical rating scale. RESULTS: Data demonstrated significant gains in LEFS and UEFI during the program. Improvement in perceived functioning was significantly correlated with a reduction in pain. CONCLUSIONS: The LEFS and UEFI provide a meaningful way to track progress in chronic pain rehabilitation. Using self-perceived measures, children and adolescents noted significant functional improvement, associated with less pain intensity. These findings increase our understanding of the rehabilitation process and point to goals for clinical improvement. AD - Therapy Services, Cleveland Clinic Children's Hospital for Rehabilitation, Cleveland, OH. Electronic address: kemperh@ccf.org. Behavioral Health Department, Cleveland Clinic Children's Hospital for Rehabilitation, Cleveland, OH. Therapy Services, Cleveland Clinic Children's Hospital for Rehabilitation, Cleveland, OH. AN - 27639440 AU - Kempert, H. AU - Benore, E. AU - Heines, R. DA - Jan DO - 10.1016/j.apmr.2016.08.471 DP - NLM ET - 2016/09/19 IS - 1 KW - Adolescent Art Therapy Child Chronic Pain/*physiopathology/*rehabilitation Female Humans Lower Extremity/physiopathology Male Music Therapy *Occupational Therapy Pain Measurement *Patient Reported Outcome Measures Perception *Physical Therapy Modalities Recreation Therapy Retrospective Studies Upper Extremity/physiopathology Young Adult *Adolescent *Chronic pain *Physical therapy specialty *Rehabilitation *Therapeutics LA - eng N1 - 1532-821x Kempert, Heidi Benore, Ethan Heines, Rachel Journal Article United States Arch Phys Med Rehabil. 2017 Jan;98(1):58-63. doi: 10.1016/j.apmr.2016.08.471. Epub 2016 Sep 14. PY - 2017 SN - 0003-9993 SP - 58-63 ST - Easily Administered Patient-Reported Outcome Measures: Adolescents' Perceived Functional Changes After Completing an Intensive Chronic Pain Rehabilitation Program T2 - Arch Phys Med Rehabil TI - Easily Administered Patient-Reported Outcome Measures: Adolescents' Perceived Functional Changes After Completing an Intensive Chronic Pain Rehabilitation Program VL - 98 ID - 3443 ER - TY - JOUR AB - OBJECTIVE: Despite recent scientific advances, children with sickle cell disease (SCD) continue to experience high mortality and significant morbidity, in part due to variations in the care provided. We sought to identify and compare drivers for quality improvement among clinical staff and parents of children with SCD. METHODS: We interviewed clinical staff across care settings in an urban teaching hospital to elicit their perspectives on improving care for children with SCD. Concurrently, we invited parents of children with SCD to participate in focus groups to identify their needs. Findings are reported according to Consolidated Criteria for Reporting Qualitative Research guidelines. RESULTS: We conducted 29 interviews with clinical staff and 4 focus groups with parents. Both groups identified the need for effective communication of relevant patient information across disciplines as a key area for improvement. Clinical staff cited standardization of care delivery as a top priority through increased accessibility of pertinent clinical information, enhanced pain assessment and management, and improved availability of clinical decision-making tools. Parents listed the need for increased community awareness about SCD, including school and day care staff, enhanced parental education and peer support, and self-management skills for their children as opportunities to improve pediatric SCD care. CONCLUSIONS: Identifying drivers for quality improvement is a critical first step in transforming the care provided to children with SCD. Using a systematic approach that includes eliciting the perspectives of both clinicians and parents may significantly enhance the development of a patient-centered quality improvement agenda. AD - Robert Wood Johnson Clinical Scholars Program, University of Pennsylvania, Philadelphia, USA. AN - 23092048 AU - Kenyon, C. C. AU - Kavanagh, P. L. AU - Fiechtner, L. G. AU - Textor, T. E. AU - Wang, C. J. DA - Jul-Aug DO - 10.1016/s0027-9684(15)30174-7 DP - NLM ET - 2012/10/25 IS - 7-8 KW - Anemia, Sickle Cell/*therapy Child Female Focus Groups Hospitals, Urban Humans Interviews as Topic Male Pediatrics/*standards Practice Patterns, Physicians'/*standards *Quality Improvement LA - eng N1 - Kenyon, Chén C Kavanagh, Patricia L Fiechtner, Lauren G Textor, Theodora E Wang, C Jason Journal Article Research Support, Non-U.S. Gov't United States J Natl Med Assoc. 2012 Jul-Aug;104(7-8):337-41. doi: 10.1016/s0027-9684(15)30174-7. PY - 2012 SN - 0027-9684 (Print) 0027-9684 SP - 337-41 ST - Setting the agenda for quality improvement in pediatric sickle cell disease T2 - J Natl Med Assoc TI - Setting the agenda for quality improvement in pediatric sickle cell disease VL - 104 ID - 3957 ER - TY - JOUR AB - Headache is acommon problem in children and adolescents that is sometimes underestimated with regard not only to frequency, but also impairment. Up to the age of 12years, 90% of children have experience of headache. With increasing age, the prevalence of headache increases, especially in girls.Headache is categorized according to the pathogenesis and type of presentation as primary, secondary or neuralgic headache. Of the primary forms of headache, tension headache outweighs migraine in childhood. Secondary headache may have numerous organic causes (meningitis, sinusitis, brain tumor, etc.).To make a diagnosis, careful history-taking (e.g. using headache diaries) and clinical as well as neurological investigations are essential. In many cases, brain imaging is unavoidable - also for forensic reasons. For this purpose, magnetic resonance imaging is the method of choice, while computed tomography remains almost exclusively reserved for acute diagnostics.For children, adolescents, parents, and teachers, primary headache is mainly associated with (school) stress. Lack of sleep, excess media consumption, alcohol, nicotine, and other substances are considered to be other factors that contribute to the genesis of headache. The first measures to be applied are silence, relaxation, fresh air, and drinking water.In headache in children and adolescents, mothers are the main contact persons. If medical aid is utilized, the prescription of analgesic drugs (e.g. ibuprofen, paracetamol) is frequent. Consequently, in the case of recurrent headache, multimodal therapy is often employed. If there is therapy resistance and chronic headache, increased or modified therapy is necessary to avoid long-term morbidity if at all possible. AN - WOS:000458876900004 AU - Kerbl, R. DA - Feb DO - 10.1007/s00608-018-0639-5 IS - 1 N1 - Kerbl, Reinhold Pinto, Andres/F-6747-2010 1613-7558 PY - 2019 SN - 0030-9338 SP - 11-15 ST - Headache in Children and Adolescents T2 - Padiatrie Und Padologie TI - Headache in Children and Adolescents UR - ://WOS:000458876900004 VL - 54 ID - 1949 ER - TY - JOUR AB - It is unknown if comorbid conditions account for the association between migraines and work performance. This issue was investigated in the National Comorbidity Survey Replication (n = 9282). Twelve-month severe or persistent migraines and other headaches were assessed with comorbid 12-month mental and physical disorders using the WHO Composite International Diagnostic Interview. Work performance was assessed using the WHO Health and Work Performance Questionnaire. Significant associations of these conditions with work disability disappeared with controls for comorbid disorders, but severe or persistent migraines continued to predict work loss days even with controls. Individual-level and societal-level annual human capital values were $1165 and $9.3 billion for this subset of migraines. Roughly 20% of these associations were due to comorbidity, 60% to direct effects and 20% to indirect effects through temporally secondary comorbidities. These strong associations suggest that workplace interventions for severe or persistent migraines might have a positive return-on-investment for employers. AD - Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA. kessler@hcp.med.harvard.edu AN - 20511212 AU - Kessler, R. C. AU - Shahly, V. AU - Stang, P. E. AU - Lane, M. C. C2 - PMC3486691 C6 - NIHMS410868 DA - Jun DO - 10.1177/0333102410363766 DP - NLM ET - 2010/06/01 IS - 6 KW - *Absenteeism Adolescent Adult Comorbidity Disability Evaluation Female Humans Male Middle Aged Migraine Disorders/*epidemiology Prevalence Young Adult LA - eng N1 - 1468-2982 Kessler, R C Shahly, V Stang, P E Lane, M C R01 DA016558/DA/NIDA NIH HHS/United States U01-MH60220/MH/NIMH NIH HHS/United States R01 MH069864/MH/NIMH NIH HHS/United States 1R13MH066849/MH/NIMH NIH HHS/United States R01-MH069864/MH/NIMH NIH HHS/United States K05 DA015799/DA/NIDA NIH HHS/United States U01 MH060220/MH/NIMH NIH HHS/United States R13 MH066849/MH/NIMH NIH HHS/United States Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Cephalalgia. 2010 Jun;30(6):722-34. doi: 10.1177/0333102410363766. Epub 2010 Mar 26. PY - 2010 SN - 0333-1024 (Print) 0333-1024 SP - 722-34 ST - The associations of migraines and other headaches with work performance: results from the National Comorbidity Survey Replication (NCS-R) T2 - Cephalalgia TI - The associations of migraines and other headaches with work performance: results from the National Comorbidity Survey Replication (NCS-R) VL - 30 ID - 3364 ER - TY - JOUR AB - OBJECTIVE: IBS is a functional gastrointestinal disorder and commonly presents in children and adolescences, presented as diarrhoea, constipation or mixed type. Blastocystis is a common intestinal protozoa found worldwide, which pathogenicity is still controversial. This study aimed to identify the risk factors of IBS, the association between IBS types with Blastocystis subtypes and analyse Blastocystis pathogenicity. DESIGN: A comparative cross-sectional study was conducted among senior high school students. Rome III Criteria for IBS diagnosis, questionnaires on the risk factors of IBS and types of IBS were recorded. Students were further selected and classified into IBS and non-IBS groups to analyse the association between IBS, IBS types with Blastocystis infection and its subtypes. Direct microscopic stool examination to identify single Blastocystis infection was performed, followed by culture in Jones' medium, PCR, sequencing of 18S rRNA and phylogenetic analysis to determine Blastocystis subtype. Data was analysed using SPSS v22.0 and P value <0.05 was considered statistically significant (95% confidence intervals). RESULTS: IBS was found in 30.2% of 454 students, consisted of 33.3% IBS Diarrhoea, 27.7% IBS Mixed, 27.7% IBS Unclassified and 11.1% IBS Constipation. Major risk factors to IBS consisted of family history of recurrent abdominal pain, abuse, bullying and female gender in respective order (OR 3.6-2.1). Blastocystis ST-1 was significantly associated to IBS-D with 2.9 times risk factor. CONCLUSIONS: Blastocystis infection is a risk factor to develop IBS-D type in adolescence; Blastocystis ST-1 can be regarded as a pathogenic subtype. AD - Department of Pediatrics, Faculty of Medicine, Universitas Sriwijaya and Moh. Hoesin Hospital, Palembang, Indonesia. Doctoral Study program, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia. Department of Pediatrics, Faculty of Medicine, Universitas Indonesia and Cipto Mangunkusumo Hospital, Jakarta, Indonesia. Department of Nutrition, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia. Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia. AN - 31528737 AU - Kesuma, Y. AU - Firmansyah, A. AU - Bardosono, S. AU - Sari, I. P. AU - Kurniawan, A. C2 - PMC6742775 DA - Aug DO - 10.1016/j.parepi.2019.e00112 DP - NLM ET - 2019/09/19 KW - Diarrhoea Intestinal protozoa Irritable bowel syndrome Risk factors LA - eng N1 - 2405-6731 Kesuma, Yudianita Firmansyah, Agus Bardosono, Saptawati Sari, Ika Puspa Kurniawan, Agnes Journal Article Parasite Epidemiol Control. 2019 May 31;6:e00112. doi: 10.1016/j.parepi.2019.e00112. eCollection 2019 Aug. PY - 2019 SN - 2405-6731 SP - e00112 ST - Blastocystis ST-1 is associated with Irritable Bowel Syndrome-diarrhoea (IBS-D) in Indonesian adolescences T2 - Parasite Epidemiol Control TI - Blastocystis ST-1 is associated with Irritable Bowel Syndrome-diarrhoea (IBS-D) in Indonesian adolescences VL - 6 ID - 4114 ER - TY - JOUR AB - INTRODUCTION: Despite the availability of a variety of evidence-based interventions, it has previously been reported that the majority of infants and children undergo vaccine injections without the benefit of analgesia. Nurses in public health administer a substantial number of injections; however, their attitudes and practices surrounding acute pain during vaccine injections have not been previously explored. METHODS: A focus-group interview was conducted in Toronto, Ontario, with 10 nurses who immunize children. Participants reported their perceptions and practices with regard to vaccine injection pain and pain management. RESULTS: Three key themes emerged: environmental and process factors, perceptions regarding the effectiveness of different analgesic interventions, and perceptions regarding pain and fear. Participants reported a lack of control over their environment, resulting in fear and discomfort for children. They recommended increased support from external partners such as school teachers and administrators. Participants reported that pharmacological interventions, such as topical local anesthetics, were not used; however, psychological and physical interventions were commonly used. Nurses questioned the effectiveness of topical anesthetics, and indicated that more education was required regarding effective analgesic interventions. Needle pain was reported to be the most prominent concern for children undergoing vaccine injections, and children were described as being fearful. DISCUSSION: Nurses reported vaccination setting, analgesic effectiveness and relative importance given to pain as important factors for pain and pain management during vaccine injections. Future studies should explore whether additional perspectives are present in vaccinators in other geographical regions. The effectiveness of educational resources and pain management programs aimed at improving current practices should be investigated. AN - WOS:000291952400003 AU - Kikuta, A. AU - Gardezi, F. AU - Dubey, V. AU - Taddio, A. DA - Sum DO - 10.1155/2011/381864 IS - 2 N1 - Kikuta, Andrew Gardezi, Fauzia Dubey, Vinita Taddio, Anna PY - 2011 SN - 1712-9532 SP - 43-48 ST - Practices and perceptions regarding pain and pain management during routine childhood immunizations: Findings from a focus-group study with nurses working at Toronto Public Health, Ontario T2 - Canadian Journal of Infectious Diseases & Medical Microbiology TI - Practices and perceptions regarding pain and pain management during routine childhood immunizations: Findings from a focus-group study with nurses working at Toronto Public Health, Ontario UR - ://WOS:000291952400003 VL - 22 ID - 2491 ER - TY - JOUR AB - Study Design: A retrospective study. Purpose: To assess the radiological, clinical features and surgical outcomes of six patients of elementary school age with lumbar disc herniation (LDH). Overview of Literature: LDH is common in people in their fourth and fifth decades. However, the condition is extremely rare in children of elementary school age. Moreover, the clinical symptoms and treatments are different from those of adults. Methods: We reviewed a series of 6 patients under the age of 12 years, who underwent surgery for LDH at our institution between 1992-2002. Initially, all patients were treated conservatively. The indications for surgery were failure of conservative treatment for 3 months, intractable pain and/or progressive neurological impairment. Results: The surgical findings revealed a protruding disc in five cases and a ruptured disc in one. In addition, separation of the vertebral ring apophysis was observed in 3 cases. The symptoms had disappeared completely at the last follow-up. At the last follow-up, the Japanese Orthopaedic Association score was 10 points in 5 cases and 9 points in 1, and the Kirkaldy Willis criteria was excellent in all patients. No intervertebral disc space narrowing was observed in any patient at last follow up. In addition, there were no degenerative changes in the vertebral endplate and facet joint. Conclusions: Patients with symptoms that persist for more than 3 months or those with a progressive neurological deficit must be considered for surgical discectomy. AN - WOS:000420302100002 AU - Kim, Y. S. AU - Park, I. J. AU - Rhyu, K. W. AU - Lee, S. U. AU - Jeong, C. DA - Jun DO - 10.4184/asj.2009.3.1.10 IS - 1 N1 - Kim, Youn-Soo Park, Il-Jung Rhyu, Kee-Won Lee, Sang-Uk Jeong, Changhoon Park, Il-Jung/0000-0001-8262-4287 1976-7846 PY - 2009 SN - 1976-1902 SP - 10-15 ST - Surgical Excision of the Lumbar Disc Herniation in Elementary School Age T2 - Asian Spine Journal TI - Surgical Excision of the Lumbar Disc Herniation in Elementary School Age UR - ://WOS:000420302100002 VL - 3 ID - 2599 ER - TY - JOUR AB - Children with sickle cell anemia have a higher-than-expected prevalence of poor educational attainment. We test two key hypotheses about educational attainment among students with sickle cell anemia, as measured by grade retention and use of special education services: (1) lower household per capita income is associated with lower educational attainment; (2) the presence of a silent cerebral infarct is associated with lower educational attainment. We conducted a multicenter, cross-sectional study of cases from 22 U.S. sites included in the Silent Infarct Transfusion Trial. During screening, parents completed a questionnaire that included sociodemographic information and details of their child's academic status. Of 835 students, 670 were evaluable; 536 had data on all covariates and were used for analysis. The students' mean age was 9.4 years (range: 5-15) with 52.2% male; 17.5% of students were retained one grade level and 18.3% received special education services. A multiple variable logistic regression model identified that lower household per capita income (odds ratio [OR] of quartile 1 = 6.36, OR of quartile 2 = 4.7, OR of quartile 3 = 3.87; P = 0.001 for linear trend), age (OR = 1.3; P < 0.001), and male gender (OR, 2.2; P = 0.001) were associated with grade retention; silent cerebral infarct (P = 0.31) and painful episodes (P = 0.60) were not. Among students with sickle cell anemia, household per capita income is associated with grade retention, whereas the presence of a silent cerebral infarct is not. Future educational interventions will need to address both the medical and socioeconomic issues that affect students with sickle cell anemia. Am. J. Hematol. 89:E188-E192, 2014. (c) 2014 Wiley Periodicals, Inc. AN - WOS:000342689200005 AU - King, A. A. AU - Rodeghier, M. J. AU - Panepinto, J. A. AU - Strouse, J. J. AU - Casella, J. F. AU - Quinn, C. T. AU - Dowling, M. M. AU - Sarnaik, S. A. AU - Thompson, A. A. AU - Woods, G. M. AU - Minniti, C. P. AU - Redding-Lallinger, R. C. AU - Kirby-Allen, M. AU - Kirkham, F. J. AU - McKinstry, R. AU - Noetzel, M. J. AU - White, D. A. AU - Kwiatkowski, J. K. AU - Howard, T. H. AU - Kalinyak, K. A. AU - Inusa, B. AU - Rhodes, M. M. AU - Heiny, M. E. AU - Fuh, B. AU - Fixler, J. M. AU - Gordon, M. O. AU - DeBaun, M. R. DA - Oct DO - 10.1002/ajh.23805 IS - 10 N1 - King, Allison A. Rodeghier, Mark J. Panepinto, Julie Ann Strouse, John J. Casella, James F. Quinn, Charles T. Dowling, Michael M. Sarnaik, Sharada A. Thompson, Alexis A. Woods, Gerald M. Minniti, Caterina P. Redding-Lallinger, Rupa C. Kirby-Allen, Melanie Kirkham, Fenella J. McKinstry, Robert Noetzel, Michael J. White, Desiree A. Kwiatkowski, Janet K. Howard, Thomas H. Kalinyak, Karen A. Inusa, Baba Rhodes, Melissa M. Heiny, Mark E. Fuh, Ben Fixler, Jason M. Gordon, Mae O. DeBaun, Michael R. Dowling, Michael M./AAE-5263-2020; Quinn, Charles T./J-6842-2012; Strouse, J/A-2690-2008; Kirkham, Fenella/C-2442-2009; Inusa, Baba/R-7447-2017 Dowling, Michael M./0000-0001-5058-6589; Quinn, Charles T./0000-0002-2372-2175; Strouse, J/0000-0003-0341-1457; Kirkham, Fenella/0000-0002-2443-7958; King, Allison/0000-0002-1951-6176; Inusa, Baba/0000-0003-2643-765X; White, Desiree/0000-0001-9439-9574 1096-8652 PY - 2014 SN - 0361-8609 SP - E188-E192 ST - Silent cerebral infarction, income, and grade retention among students with sickle cell anemia T2 - American Journal of Hematology TI - Silent cerebral infarction, income, and grade retention among students with sickle cell anemia UR - ://WOS:000342689200005 VL - 89 ID - 2283 ER - TY - JOUR AB - This program evaluated the effectiveness of a sickle cell disease (SCD) education program for teachers of students with SCD in their classroom. Teachers with students in a remediation program for students participated in an educational program consisiting of four domains: Inheritance and Prevalence, Common Complications, Strokes, and Individual Education Plans (IEP). A 30- to 45-minute presentation was given with a pretest and posttest. Eighty-one teachers who taught grades K-12 completed the program. Most teachers understood the complications of fever and pain, risks of strokes occurring at any age, and the purpose of IEPs. Overall the rate of correct answers increased from 72.5% to 83.1%, p = 0.0001. Teachers improved their understanding of heredity (32% vs. 66%, p = 0.0001), prevalence (81% vs. 94%, p = 0.039), silent stroke diagnosis (21% vs. 80%, p = 0.0001) and overt stroke therapy (40% vs. 75%, p = 0.0001). No significant impact on teacher knowledge occurred for the contents of IEPs (80% vs. 87%, p = 0.227). Teachers of students with SCD increased knowledge about SCD following the program. AN - WOS:000226952200003 AU - King, A. A. AU - Tang, S. J. AU - Ferguson, K. L. AU - DeBaun, M. R. DA - Jan DO - 10.1111/j.1746-1561.2005.tb00003.x IS - 1 N1 - King, AA Tang, SJ Ferguson, KL DeBaun, MR King, Allison/0000-0002-1951-6176 PY - 2005 SN - 0022-4391 SP - 11-14 ST - An education program to increase teacher knowledge about sickle cell disease T2 - Journal of School Health TI - An education program to increase teacher knowledge about sickle cell disease UR - ://WOS:000226952200003 VL - 75 ID - 2778 ER - TY - JOUR AB - Background. School-based relaxation training programmes are a popular means of helping children with anxiety problems such as headaches and test anxiety. Aims. Our major objective is to evaluate the empirical status of school-based relaxation training programmes. Contents. Focusing on progressive muscle relaxation training, we show how this adult training procedure has been modified for use with children. Several training issues are discussed including the questions of live versus recorded instruction and individual versus group instruction. We also discuss the evaluation of relaxation training programmes in school settings, highlighting issues of reliability and validity. Conclusions. Our review of studies examining the efficacy of school-based relaxation training shows that improvements are usually modest and of dubious clinical or educational significance. Consequently we suggest that when relaxation training is used with school children treatment goals should be more modest or, that if improvements in specific performance areas are sought, then more comprehensive treatment packages be developed which can influence the successful performance of children in target areas and reduce anxiety to normal levels. AN - WOS:000072995600006 AU - King, N. J. AU - Ollendick, T. H. AU - Murphy, G. C. AU - Molloy, G. N. DA - Mar DO - 10.1111/j.2044-8279.1998.tb01274.x N1 - King, NJ Ollendick, TH Murphy, GC Molloy, GN 1 PY - 1998 SN - 0007-0998 SP - 53-66 ST - Utility of relaxation training with children in school settings: a plea for realistic goal setting and evaluation T2 - British Journal of Educational Psychology TI - Utility of relaxation training with children in school settings: a plea for realistic goal setting and evaluation UR - ://WOS:000072995600006 VL - 68 ID - 2899 ER - TY - JOUR AB - Objective To investigate the causes of neurological manifestations in girls immunized with the human papillomavirus (HPV) vaccine. Methods During the past nine months, 44 girls visited us complaining of several symptoms after HPV vaccination. Four patients with other proven disorders were excluded, and the remaining forty subjects were enrolled in this study. Results The age at initial vaccination ranged from 11 to 17 years, and the average incubation period after the first dose of the vaccine was 5.47 +/- 5.00 months. Frequent manifestations included headaches, general fatigue, coldness of the legs, limb pain and weakness. The skin temperature examined in 28 girls with limb symptoms exhibited a slight decrease in the fingers (30.4 +/- 2.6 degrees C) and a moderate decrease in the toes (27.1 +/- 3.7 degrees C). Digital plethysmograms revealed a reduced height of the waves, especially in the toes. The limb symptoms of four girls were compatible with the Japanese clinical diagnostic criteria for complex regional pain syndrome (CRPS), while those in the other 14 girls were consistent with foreign diagnostic criteria for CRPS. The Schellong test identified eight patients with orthostatic hypotension and four patients with postural orthostatic tachycardia syndrome. The girls with orthostatic intolerance and CRPS commonly experienced transient violent tremors and persistent asthenia. Electron-microscopic examinations of the intradermal nerves showed an abnormal pathology in the unmyelinated fibers in two of the three girls examined. Conclusion The symptoms observed in this study can be explained by abnormal peripheral sympathetic responses. The most common previous diagnosis in the studied girls was psychosomatic disease. The social problems of the study participants remained unresolved in that the severely disabled girls stopped going to school. AN - WOS:000343037100003 AU - Kinoshita, T. AU - Abe, R. AU - Hineno, A. AU - Tsunekawa, K. AU - Nakane, S. AU - Ikeda, S. DO - 10.2169/internalmedicine.53.3133 IS - 19 N1 - Kinoshita, Tomomi Abe, Ryu-ta Hineno, Akiyo Tsunekawa, Kazuhiro Nakane, Shunya Ikeda, Shu-ichi 1349-7235 PY - 2014 SN - 0918-2918 SP - 2185-2200 ST - Peripheral Sympathetic Nerve Dysfunction in Adolescent Japanese Girls Following Immunization with the Human Papillomavirus Vaccine T2 - Internal Medicine TI - Peripheral Sympathetic Nerve Dysfunction in Adolescent Japanese Girls Following Immunization with the Human Papillomavirus Vaccine UR - ://WOS:000343037100003 VL - 53 ID - 2330 ER - TY - JOUR AB - Late-onset idiopathic aqueductal stenosis (LIAS) has been recognized as one of the clinical entities of adulthood hydrocephalus for decades, although there have been no radiological reports that show normal ventricular systems before the development of LIAS. We present here an adolescent case of LIAS with a previously normal ventricular system on magnetic resonance imaging (MRI). A 17-year-old boy had been suffering from chronic headaches and mild intellectual disability (MID) since he became a teenager, and this had prevented him from leading an ordinary school life. MRIs on admission showed triventriculomegaly from the aqueductal stenosis that had not been detected on previous MRIs, at least until the age of 6. An endoscopic third ventriculostomy was successfully performed, which improved both the headache and the MID. The developmental mechanism of LIAS remains unclear, although the membranous ependymal-like tissue observed in the aqueduct suggested the preceding existence of an inflammatory process around this region. To the best of our knowledge, this case was noteworthy because the development of LIAS was clearly demonstrated on MRI for the first time. AN - WOS:000338631100027 AU - Kita, D. AU - Hayashi, Y. AU - Kitabayashi, T. AU - Kinoshita, M. AU - Okajima, M. AU - Taniguchi, T. AU - Hamada, J. DA - Jul DO - 10.1007/s00381-014-2354-2 IS - 7 N1 - Kita, Daisuke Hayashi, Yasuhiko Kitabayashi, Tomohiro Kinoshita, Masashi Okajima, Michiko Taniguchi, Takumi Hamada, Jun-ichiro Kinoshita, Masashi/AAL-4312-2021 Kinoshita, Masashi/0000-0002-2148-8231 1433-0350 PY - 2014 SN - 0256-7040 SP - 1317-1319 ST - Detection of the development of late-onset idiopathic aqueductal stenosis (LIAS) by chronological magnetic resonance imaging: a case report T2 - Childs Nervous System TI - Detection of the development of late-onset idiopathic aqueductal stenosis (LIAS) by chronological magnetic resonance imaging: a case report UR - ://WOS:000338631100027 VL - 30 ID - 2300 ER - TY - JOUR AB - Low back pain syndromes are in the group of the commonest diseases observed in recent years and bear serious medical, social and economical burden. According to European data more than 70% of population suffered from back pain at least for a week in the lifetime, and 15-40% of population experiences low back pain every year. There is alarming decrease in the age of first onset described by many authors. Peak morbidity is observed in persons aged between 35 and 55 years, but a recent Japanese study brings evidence that 66.7% of middle-school children has already experienced low back pain lasting for at least 1 week, and relapse rate exceeds 60%. Increase of incidence and morbidity of low back pain is linked to lifestyle alterations including significant limitation of physical activities since young age, changes of hobby preferences, alteration of work habits favoring activities performed in improper body position lasting for hours or even years, to dynamic physical work. Pain may be presented in any phase of spinal overload syndromes. Back pain may result from nocyceptive activation in spinal, paraspinal tissues as well as irritating of nervous structures within vertebral canal, when appears as a neuropathic pain. Pain in spondylolisthesis may be related to ligamentous constrain, particularly when posterior longitudinal ligament (densely supplied with nocyceptive endings) is involved. The paper describes the commonest back pain syndromes and spinal deformities resulting from long-lasting overload with their typical presentation. AD - Wyzsza Szkoła Rehabilitacji w Warszawie. jerzy.kiwerski@wsr.edu.pl AN - 22026277 AU - Kiwerski, J. E. DP - NLM ET - 2011/10/27 IS - 2 KW - Adolescent Adult Age Distribution Aged Back Pain/*epidemiology Humans Incidence Low Back Pain/epidemiology Middle Aged Recurrence Risk Factors Young Adult LA - pol N1 - Kiwerski, Jerzy E English Abstract Journal Article Review Poland Wiad Lek. 2011;64(2):118-21. OP - Czynniki wpływajace na czestość wystepowania zespołów bólowych kregosłupa. PY - 2011 SN - 0043-5147 (Print) 0043-5147 SP - 118-21 ST - [Factors effecting frequency of occurrence of back pain syndromes] T2 - Wiad Lek TI - [Factors effecting frequency of occurrence of back pain syndromes] VL - 64 ID - 3020 ER - TY - JOUR AB - Ninety-two chronic low back pain patients were randomly allocated to two groups to evaluate the effectiveness of a back school compared with an exercise-only regimen according to specified outcome variables. The data from 78 patients with 7 years mean duration of symptoms was analyzed. Three assessments were made: before treatment and 6 and 16 weeks after treatment. Changes in patients' levels of pain, functional disability, and other related variables were compared in the two groups. Almost all variables showed an improvement at 6 weeks. At 16 weeks, functional disability and pain levels showed a significant difference. Back school patients continued to make an improvement. This method of managing low back pain makes maximal use of limited resources and appears to be effective, especially in the longer term. AN - 2939571 AU - Klaber Moffett, J. A. AU - Chase, S. M. AU - Portek, I. AU - Ennis, J. R. DA - Mar DO - 10.1097/00007632-198603000-00003 DP - NLM ET - 1986/03/01 IS - 2 KW - Adolescent Adult Aged Back Pain/*rehabilitation Clinical Trials as Topic Disability Evaluation Double-Blind Method *Exercise Therapy Female Humans Male Middle Aged *Patient Education as Topic Random Allocation Time Factors LA - eng N1 - Klaber Moffett, J A Chase, S M Portek, I Ennis, J R Clinical Trial Comparative Study Journal Article Randomized Controlled Trial United States Spine (Phila Pa 1976). 1986 Mar;11(2):120-2. doi: 10.1097/00007632-198603000-00003. PY - 1986 SN - 0362-2436 (Print) 0362-2436 SP - 120-2 ST - A controlled, prospective study to evaluate the effectiveness of a back school in the relief of chronic low back pain T2 - Spine (Phila Pa 1976) TI - A controlled, prospective study to evaluate the effectiveness of a back school in the relief of chronic low back pain VL - 11 ID - 4022 ER - TY - JOUR AB - Purpose: Children and adolescents with primary headache are at risk of persistent somatic symptoms and reduced quality of life (Qol) due to pain and pain-related behaviors, such as avoiding school and activities. Sleep is essential to health, and children and adolescents with primary headaches have more sleep complaints than do healthy controls. A treatment approach that addresses multifactorial causes is likely important. Nonpharmacological interventions seem promising. However, knowledge about effective strategies is limited. The objective of this review is to assess the effect of nonpharmacological interventions in randomized controlled trials (RCTs) among children and adolescents with primary headache in order to identify useful strategies. Patients and methods: Outcome measures are pain, sleep, Qol, and coping versus no intervention or control intervention. Medline, CINAHL, EMBASE, and PsycINFO were searched for eligible trials ClinicalTrials.gov. was searched for ongoing trials Initial searches yielded 2588 publications. After initial screening and subsequent full-text review and quality assessment, 13 RCTs reported in 15 articles were selected for review. All reviewers independently assessed study quality using the CONSORT criteria for nonpharmacological interventions. Results: Cognitive behavioral therapy (CBT), including education on pain-related topics, sleep, coping, and stress management, is an effective strategy for reducing headache and pain within groups over time. Fifteen studies assessed pain, 3 studies assessed sleep, 6 studies assessed Qol, and 11 studies assessed coping. Conclusion: Strategies identified as useful were parts of CBT interventions. However, it was not possible to identify a single effective intervention addressing pain, sleep, Qol, and coping in children and adolescents with headache, primarily because sleep was infrequently addressed. Various aspects of Qol and coping strategies were assessed, rendering comparison difficult. Strategies for future interventions should include descriptions of theory-driven CBT interventions, depending on clinical setting and based on local resources, to promote a solid evidence base for nonpharmacological interventions. AN - WOS:000503958400001 AU - Klausen, S. H. AU - Ronde, G. AU - Tornoe, B. AU - Bjerregaard, L. DO - 10.2147/jpr.S216807 N1 - Klausen, Susanne Hwiid Ronde, Gitte Tornoe, Birte Bjerregaard, Lene Bjerregaard, Lene Berit Skov/X-7176-2019 Bjerregaard, Lene Berit Skov/0000-0002-3952-5301; Klausen, Susanne Hwiid/0000-0002-8968-1812 PY - 2019 SN - 1178-7090 SP - 3437-3459 ST - Nonpharmacological Interventions Addressing Pain, Sleep, and Quality of Life in Children and Adolescents with Primary Headache: A Systematic Review T2 - Journal of Pain Research TI - Nonpharmacological Interventions Addressing Pain, Sleep, and Quality of Life in Children and Adolescents with Primary Headache: A Systematic Review UR - ://WOS:000503958400001 VL - 12 ID - 1963 ER - TY - JOUR AB - OBJECTIVE: The aim of this review was to evaluate the complications of spinal cord stimulation (SCS) for chronic pain. METHODS: This was a retrospective case series of 212 patients treated with SCS for chronic lower-limb neuropathic pain between March 2002 and February 2015 in a Reims academic hospital. All patients received a surgically implanted paddle-type electrode. Complications with this technique are here described and analyzed, and other treatment and preventative methods proposed. RESULTS: The major indication was 'failed back surgery syndrome', and 74 (35%) patients experienced complications, of which 57% were benign, while 42% required invasive treatment. Most frequent complications (n=22, 10%) were hardware malfunctions. There were two cases (0.9%) of postoperative neurological deficit and nine (4.2%) with postoperative infections. All patients received the appropriate treatment for their complication. CONCLUSION: Despite the presence of complications, SCS is still a safe technique, although careful patient selection and proper surgical technique can help to avoid major complications. AD - Service de Neurochirurgie, Hôpital Maison-Blanche, CHU de Reims, 45, rue Cognacq-Jay, 51100 Reims, France. Electronic address: jean-charles.kleiber@neurochirurgie.fr. Service de Neurochirurgie, Hôpital Maison-Blanche, CHU de Reims, 45, rue Cognacq-Jay, 51100 Reims, France. AN - 27776893 AU - Kleiber, J. C. AU - Marlier, B. AU - Bannwarth, M. AU - Theret, E. AU - Peruzzi, P. AU - Litre, F. DA - Nov DO - 10.1016/j.neurol.2016.09.003 DP - NLM ET - 2016/10/26 IS - 11 KW - Adolescent Adult Aged Chronic Pain/epidemiology/*therapy Electric Stimulation Therapy/adverse effects/instrumentation/methods *Electrodes, Implanted/adverse effects/statistics & numerical data Female Humans Male Middle Aged Postoperative Complications/epidemiology/*etiology Retrospective Studies Spinal Cord Stimulation/*adverse effects/instrumentation/statistics & numerical data Treatment Outcome Young Adult Chronic pain Complications Spinal cord stimulation LA - eng N1 - Kleiber, J-C Marlier, B Bannwarth, M Theret, E Peruzzi, P Litre, F Journal Article France Rev Neurol (Paris). 2016 Nov;172(11):689-695. doi: 10.1016/j.neurol.2016.09.003. Epub 2016 Oct 21. PY - 2016 SN - 0035-3787 (Print) 0035-3787 SP - 689-695 ST - Is spinal cord stimulation safe? A review of 13 years of implantations and complications T2 - Rev Neurol (Paris) TI - Is spinal cord stimulation safe? A review of 13 years of implantations and complications VL - 172 ID - 3485 ER - TY - JOUR AB - The author reviews conceptual and empirical issues regarding the interaction of neurasthenia, somatization and depression in Chinese culture and in the West. The historical background of neurasthenia and its current status are discussed, along with the epidemiology and phenomenology of somatization and depression. Findings are presented from a combined clinical and anthropological field study of 100 patients with neurasthenia in the Psychiatry Outpatient Clinic at the Hunan Medical College. Eighty-seven of these patients made the DSM-III criteria of Major Depressive Disorder; diagnoses of anxiety disorders were also frequent. Forty-four patients were suffering from chronic pain syndromes previously undiagnosed, and cases of culture-bound syndromes also were detected. For three-quarters of patients the social significances and uses of their illness behavior chiefly related to work. Although from the researcher's perspective 70% of patients with Major Depressive Disorder experienced substantial improvement and 87% some improvement in symptoms when treated with antidepressant medication, fewer experienced decreased help seeking, and a much smaller number perceived less social impairment and improvement in illness problems (the psychosocial accompaniment of disease including maladaptive coping and work, family and school problems). These findings are drawn on to advance medical anthropology and cultural psychiatry theory and research regarding somatization in Chinese culture, the United States and cross culturally. The author concludes that though neurasthenia can be understood in several distinctive ways, it is most clinically useful to regard it as bioculturally patterned illness experience (a special form of somatization) related to either depression and other diseases or to culturally sanctioned idioms of distress and psychosocial coping. AN - 7116909 AU - Kleinman, A. DA - Jun DO - 10.1007/bf00051427 DP - NLM ET - 1982/06/01 IS - 2 KW - Adolescent Adult China Cultural Characteristics Depressive Disorder/epidemiology/*psychology Family Female Field Dependence-Independence Headache Humans Language Life Change Events Male Mental Disorders/diagnosis Middle Aged Models, Psychological Neurasthenia/diagnosis/epidemiology/*psychology Outcome and Process Assessment, Health Care Pain Patient Acceptance of Health Care Somatoform Disorders/psychology Suicide, Attempted/psychology LA - eng N1 - Kleinman, A Case Reports Journal Article Netherlands Cult Med Psychiatry. 1982 Jun;6(2):117-90. doi: 10.1007/BF00051427. PY - 1982 SN - 0165-005X (Print) 0165-005x SP - 117-90 ST - Neurasthenia and depression: a study of somatization and culture in China T2 - Cult Med Psychiatry TI - Neurasthenia and depression: a study of somatization and culture in China VL - 6 ID - 4014 ER - TY - JOUR AB - INTRODUCTION: University students are subjected to different kinds of stressors, i.e.academic pressures, social issues and financial problems. This can affect their academic achievements and quality of life. OBJECTIVE: The aim of this study was to determine the health-related quality of life of university students, and how it is affected by the presence of chronic diseases, mental disorders comorbidity, and patterns of medical services' use. METHODS: This web-based study included a sample of 1,410 Slovenian university students. We used a self-administered questionnaire, containing a sheet with demographic data, Zung's self-assessment inventories about anxiety and depression, and EQ-5D questionnaire. The main outcome measures were scores on EQ-5D part and VAS part of the EQ-5D questionnaire. RESULTS: Independent factors associated with the health-related quality of life of university students, were the presence of chronic pain, the presence of depression and anxiety, need for urgent medical help and at least one visit to a clinical specialist in the past year. The independent factors associated with the health status of university students were the presence of chronic diseases, chronic pain, depression and anxiety, a visit to a clinical specialist, a need for urgent medical help and a visit to an emergency unit in the past year. CONCLUSION: Health-related quality of life of university students can be seriously affected by the presence of mental disorders and chronic pain. Appropriate health-related measures should be adopted to achieve early recognition of worse health-related quality of life, the presence of mental disorders and other chronic conditions, and to enable their effective treatment. AD - Department of Family Medicine, Medical School, University of Maribor, Maribor, Slovenia. zalika.klemenc-ketis@uni-mb.si AN - 21618866 AU - Klemenc-Ketis, Z. AU - Kersnik, J. AU - Eder, K. AU - Colaric, D. DA - Mar-Apr DO - 10.2298/sarh1104197k DP - NLM ET - 2011/05/31 IS - 3-4 KW - Chronic Disease/epidemiology Female *Health Status Humans Male Mental Disorders/epidemiology *Quality of Life Slovenia *Students Universities Young Adult LA - eng N1 - Klemenc-Ketis, Zalika Kersnik, Janko Eder, Ksenija Colaric, Dusan Journal Article Serbia Srp Arh Celok Lek. 2011 Mar-Apr;139(3-4):197-202. doi: 10.2298/sarh1104197k. PY - 2011 SN - 0370-8179 (Print) 0370-8179 SP - 197-202 ST - Factors associated with health-related quality of life among university students T2 - Srp Arh Celok Lek TI - Factors associated with health-related quality of life among university students VL - 139 ID - 3792 ER - TY - JOUR AB - Subject of the present study are individual pain concepts of preschoolers and children of early school age. Their parents' concepts of pain were considered as well. In a qualitative study interviews were performed with 9 children and their parents in a children's hospital to investigate their individual concepts of pain, their methods of pain assessment, and self-initiated strategies of pain alleviation. Already 4-6 year old children are able to remember painful experiences and to communicate about pain. Strategies of pain alleviation used by children are distraction methods as well as methods of physical relief. The child's parents play an important role concerning pain assessment and coping. The parents' presence is also very important to communicate the child's needs to nurses. Parents want nurses to consider physiological as well as behavioral aspects in the assessment of the child's pain. Besides, they expect nurses to have competences concerning prevention, assessment and alleviation of pain. To perform a trustful relationship to children and parents, more intensified counselling by nurses seems necessary. AD - Fachbereich Pflege und Gesundheit, Fachhochschule Frankfurt/Main. AN - 10578904 AU - Kloos, H. D. DA - Jun DO - 10.1024/1012-5302.12.3.173 DP - NLM ET - 1999/12/01 IS - 3 KW - Adult *Attitude to Health Child Child, Hospitalized/*psychology Child, Preschool Clinical Competence/standards Humans Nursing Assessment/standards Nursing Methodology Research Nursing Staff, Hospital/education/psychology Pain/diagnosis/*psychology Pain Management Pain Measurement Parents/education/*psychology Pediatric Nursing/standards Professional-Family Relations *Psychology, Child Surveys and Questionnaires LA - ger N1 - Kloos, H D English Abstract Journal Article Switzerland Pflege. 1999 Jun;12(3):173-82. doi: 10.1024/1012-5302.12.3.173. OP - Schmerzkonzepte von Kindern im Vorschul- und frühen Schulalter und ihrer Eltern nach schmerzhaften Interventionen während eines Krankenhausaufenthaltes. PY - 1999 SN - 1012-5302 (Print) 1012-5302 SP - 173-82 ST - [Concepts of pain in preschoolers and children of early school age and their parents after painful interventions during hospitalization] T2 - Pflege TI - [Concepts of pain in preschoolers and children of early school age and their parents after painful interventions during hospitalization] VL - 12 ID - 3341 ER - TY - JOUR AB - The intelligence quotient (IQ) of 60 patients with homozygous sickle cell (SS) disease and 60 age and sex matched controls with a normal haemoglobin (AA) genotype aged 15-18 years, followed up in a cohort study fi om birth, was assessed by the Wechsler intelligence scales for children or for adults. IQ appeared to be normally distributed in both genotypes but mean values in SS disease were 5.6 points (95% confidence interval (CI) 1.0 to 10.2) lower than in AA controls (p=0.016). The difference occurred in both verbal (5.5 points, p=0.017) and performance (5.0 points, p=0.044) subscales of the IQ score and the IQ defect in SS disease was associated with a significantly lower attention factor score (p=0.005) but not with other factor scores. The genotype difference in IQ was not accounted for by differences in parental occupational revel, school absenteeism, or school drop out, or reported activity level. In SS disease, IQ was not related to mean steady state haemoglobin, fetal haemoglobin, or mean cell haemoglobin concentration, or clinical severity as judged by the frequency of painful crises, hospital admission, or sick visits. IQ, at age 15-18 years, correlated with the patients' height at all ages from 1 to 10 years (partial correlations increasing from 0.14 (p=0.15) at age 1 to 0.27 (p=0.004) at age 10). Adjusting for height reduced the mean genotype difference in IQ to 5.5 (95% CI 0.6 to 10.3) points at age 1 and to 2.6 points (95% CI to -2.3, 7.5) at age 10. Prepubertal height therefore accounted for much of the genotype difference in IQ. It is speculated that early factors, possibly nutritional, contribute to both impaired growth and mental development in sickle cell disease. AN - WOS:A1995RZ82300008 AU - Knight, S. AU - Singhal, A. AU - Thomas, P. AU - Serjeant, G. DA - Oct DO - 10.1136/adc.73.4.316 IS - 4 N1 - Knight, s singhal, a thomas, p serjeant, g Thomas, Peter/0000-0003-2478-4324 PY - 1995 SN - 0003-9888 SP - 316-320 ST - FACTORS ASSOCIATED WITH LOWERED INTELLIGENCE IN HOMOZYGOUS SICKLE-CELL DISEASE T2 - Archives of Disease in Childhood TI - FACTORS ASSOCIATED WITH LOWERED INTELLIGENCE IN HOMOZYGOUS SICKLE-CELL DISEASE UR - ://WOS:A1995RZ82300008 VL - 73 ID - 2933 ER - TY - JOUR AB - The aim of this study was to evaluate bite force (BF) and oro-facial functions at different dentition phases (initial-mixed, intermediate-mixed, final-mixed and permanent dentition) in children and adolescents diagnosed with temporomandibular disorders (TMDs). The sample was selected from four public schools in Piracicaba, São Paulo, Brazil. Of the 289 participants recruited, aged 8-14 years old, 46 were placed into the TMD group. TMD was diagnosed using Axis I of the Research Diagnostic Criteria for Temporomandibular Disorders (2011). Oro-facial functions were evaluated using the Nordic Orofacial Test-Screening (NOT-S), which involves both an interview and a clinical examination. BF was measured using a digital gnathodynamometer. Age and body mass index (BMI) were also considered. The data were analysed by the following tests: Kolmogorov-Smirnov test, Student's t-test, Spearman and Pearson coefficients, Qui-square test, Fisher's exact or binomial test, as indicated. Moreover, univariate and multivariable logistic regression were applied. For the TMD group, scores associated with NOT-S interview and NOT-S total were higher than for the control group (P = 0.033 and P = 0.0062, respectively). No differences in BF between genders or groups (P > 0.05) were detected. Variables included in the multivariate logistic regression were BMI and NOT-S total. Based on this analysis, NOT-S total was associated with TMDs. Reported sensory function was the specific domain within NOT-S interview that established the significant difference between the groups (P = 0.021). The TMD group also had a greater number of alterations in the face-at-rest domain of the NOT-S exam (P = 0.007). Concluding, it did not detect an association between TMDs and either dentition phase or BF. Instead, BF correlated with age and BMI. Oro-facial dysfunction was associated with TMD in the studied sample, but this association may be bidirectional, requiring further researches. AD - Department of Pediatric Dentistry, Piracicaba Dental School, University of Campinas-UNICAMP, Piracicaba, Brazil. AN - 24661101 AU - Kobayashi, F. Y. AU - Gavião, M. B. AU - Montes, A. B. AU - Marquezin, M. C. AU - Castelo, P. M. DA - Jul DO - 10.1111/joor.12163 DP - NLM ET - 2014/03/26 IS - 7 KW - Adolescent Age Factors *Bite Force Body Mass Index Brazil Child *Dentition, Mixed Female Humans Male Temporomandibular Joint Dysfunction Syndrome/*physiopathology bite force dentition oral function temporomandibular joint LA - eng N1 - 1365-2842 Kobayashi, F Y Gavião, M B D Montes, A B M Marquezin, M C S Castelo, P M Journal Article Multicenter Study Research Support, Non-U.S. Gov't England J Oral Rehabil. 2014 Jul;41(7):496-506. doi: 10.1111/joor.12163. Epub 2014 Mar 24. PY - 2014 SN - 0305-182x SP - 496-506 ST - Evaluation of oro-facial function in young subjects with temporomandibular disorders T2 - J Oral Rehabil TI - Evaluation of oro-facial function in young subjects with temporomandibular disorders VL - 41 ID - 3154 ER - TY - JOUR AB - Objectives: In order to control pain, which is a prevalent problem, gathering knowledge regarding pain and pain beliefs is crucial. The aim of this study was to evaluate the correlation between pain and pain beliefs and the sociodemographic and economic characteristics of an adult population. Methods: This descriptive, cross-sectional study was completed with 131 individuals aged between 18-65 years. A questionnaire evaluating sociodemographic and economic status and pain characteristics and the Pain Beliefs Scale were used for data collection. Results: 78.6% of the research group experienced pain within the last year; of them, 38.8% suffered from chronic pain. According to the results of logistic regression analysis, the risk factors were determined as age between 30- 65 years (odds ratio [OR]: 0.215; p=0.008) and graduation from elementary school and lower education level (OR=3.427; p=0.021) for experiencing lifelong frequent pain; being female (OR=3.003; p=0.016) and married (OR=4.550; p=0.005) for experiencing pain within the last year; and age between 30- 65 years (OR=3.027; p=0.027) and lower income (OR=4.932 ;p=0.001) for chronic pain. The organic and psychological pain beliefs scores were similar. Sociodemographic and economic determinants were not significant for the organic subscale (p>0.05), but lower income determined 11% of the psychological subscale (R2=0.115; p<0.05). Conclusion: Sociodemographic and economic status were determined to be risk factors for experiencing pain, and cultural factors related to pain beliefs warrant investigation. AN - WOS:000421197900004 AU - Kocoglu, D. AU - Ozdemir, L. DA - Apr DO - 10.5505/agri.2011.93063 IS - 2 N1 - Kocoglu, Deniz Ozdemir, Leyla PY - 2011 SN - 1300-0012 SP - 64-70 ST - The relation between pain and pain beliefs and sociodemographic-economic characteristics in an adult population T2 - Agri-the Journal of the Turkish Society of Algology TI - The relation between pain and pain beliefs and sociodemographic-economic characteristics in an adult population UR - ://WOS:000421197900004 VL - 23 ID - 2503 ER - TY - JOUR AB - Background: While several population-based studies report that pain is independently associated with higher rates of self-destructive behaviour (suicidal ideation, suicide attempts, and self-injurious behaviour) in adults, studies in adolescents are rare and limited to specific chronic pain conditions. The aim of this study was to investigate the link between self-reported idiopathic pain and the prevalence and frequency of self-injury (SI) and suicide attempts in adolescents. Methods: Data from a cross-sectional, school-based sample was derived to assess SI, suicide attempts, recurrent pain symptoms and various areas of emotional and behavioural problems via a self-report booklet including the Youth Self-Report (YSR). Adolescents were assigned to two groups (presence of pain vs. no pain) for analysis. Data from 5,504 students of 116 schools in a region of South Western Germany was available. A series of unadjusted and adjusted multinomial logistic regression models were performed to address the association of pain, SI, and suicide attempts. Results: 929 (16.88%) respondents reported recurrent pain in one of three areas of pain symptoms assessed (general pain, headache, and abdominal pain). Adolescents who reported pain also reported greater psychopathological distress on all sub-scales of the YSR. The presence of pain was significantly associated with an increased risk ratio (RR) for SI (1-3 incidences in the past year: RR: 2.96; >3 incidences: RR: 6.04) and suicide attempts (one attempt: RR: 3.63; multiple attempts: RR: 5.4) in unadjusted analysis. Similarly, increased RR was observed when adjusting for sociodemographic variables. While controlling for psychopathology attenuated this association, it remained significant (RRs: 1.4-1.8). Sub-sequent sensitivity analysis revealed different RR by location and frequency of pain symptoms. Conclusions: Adolescents with recurrent idiopathic pain are more likely to report previous incidents of SI and suicide attempts. This association is likely mediated by the presence of psychopathological distress as consequence of recurrent idiopathic pain. However, the observed variance in dependent variables is only partially explained by emotional and behavioural problems. Clinicians should be aware of these associations and interview adolescents with recurrent symptoms of pain for the presence of self-harm, past suicide attempts and current suicidal thoughts. Future studies addressing the neurobiology underpinnings of an increased likelihood for self-injurious behaviour and suicide attempts in adolescents with recurrent idiopathic pain are necessary. AN - WOS:000370941900002 AU - Koenig, J. AU - Oelkers-Ax, R. AU - Parzer, P. AU - Haffner, J. AU - Brunner, R. AU - Resch, F. AU - Kaess, M. C7 - 32 DA - Sep DO - 10.1186/s13034-015-0069-0 N1 - Koenig, Julian Oelkers-Ax, Rieke Parzer, Peter Haffner, Johann Brunner, Romuald Resch, Franz Kaess, Michael Koenig, Julian/J-8863-2017 Koenig, Julian/0000-0003-1009-9625 1753-2000 PY - 2015 ST - The association of self-injurious behaviour and suicide attempts with recurrent idiopathic pain in adolescents: evidence from a population-based study T2 - Child and Adolescent Psychiatry and Mental Health TI - The association of self-injurious behaviour and suicide attempts with recurrent idiopathic pain in adolescents: evidence from a population-based study UR - ://WOS:000370941900002 VL - 9 ID - 2222 ER - TY - JOUR AB - This article endeavored to determine the topics of discussion during open-ended peer mentoring between adolescents and young adults living with chronic illness. This study occurred alongside a study of the iPeer2Peer Program. Fifty-two calls (7 mentor-mentee pairings) were audio recorded, transcribed verbatim, and analyzed using inductive coding with an additional 30 calls (21 mentor-mentee pairings) coded to ensure representativeness of the data. Three categories emerged: (1) illness impact (e.g., relationships, school/work, self-identity, personal stories), (2) self-management (e.g., treatment adherence, transition to adult care, coping strategies), and (3) non-illness-related adolescent issues (e.g., post-secondary goals, hobbies, social environments). Differences in discussed topics were noted between sexes and by diagnosis. Peer mentors provided informational, appraisal, and emotional support to adolescents. AN - WOS:000430332700003 AU - Kohut, S. A. AU - Stinson, J. AU - Forgeron, P. AU - van Wyk, M. AU - Harris, L. AU - Luca, S. DA - May DO - 10.1177/1359105316669877 IS - 6 N1 - Kohut, Sara Ahola Stinson, Jennifer Forgeron, Paula van Wyk, Margaret Harris, Lauren Luca, Stephanie Ahola Kohut, Sara/0000-0003-1562-947X; van Wyk, Margaret/0000-0002-8073-7322 1461-7277 PY - 2018 SN - 1359-1053 SP - 788-799 ST - A qualitative content analysis of peer mentoring video calls in adolescents with chronic illness T2 - Journal of Health Psychology TI - A qualitative content analysis of peer mentoring video calls in adolescents with chronic illness UR - ://WOS:000430332700003 VL - 23 ID - 2017 ER - TY - JOUR AB - Menstrual symptoms may have a significant impact on women's lives. Many women experience menses-related health problems, such as menstrual pain, heavy menstrual bleeding, and premenstrual syndrome, during their reproductively fertile years. Circadian misalignment in shift workers has been reported to contribute to menstrual cycle irregularity and/or painful menstruation. However, the relationship between social jetlag (SJL) and menstrual symptoms/menstrual cycle has not been elucidated. In this study, we aimed to elucidate this relationship among female university students. One-hundred and fifty female university students (mean [SD]: 18.8 [0.71]-years old) completed self-reported questionnaires consisting of menstrual symptoms and menstrual cycle, sleep quality and sleep habits, quality of life, and demographic variables. The average menstrual cycle was 32.0 [5.4] days. The percentage of students who showed menstrual cycle irregularity, having less than 25 days or more than 39 days of menstrual cycle during the previous four menstrual cycles, was 60.6%. SJL, the difference between mid-sleep time on free days and mid-sleep time on school days, was categorized into small (absolute SJL < 1 h) or large (>= 1 h). Overall, 78.0% of participants had SJL >= 1 h. Among the menstrual symptoms, pain, behavioral change, and water retention subscale scores were significantly higher in the SJL >= 1 h group than in the SJL < 1 h group. However, no significant differences were found in concentration, autonomic reaction, or negative affect subscale scores between the two groups. The menstrual cycle was 31.2 [5.5] days in the SJL < 1 h group and 32.2 [5.4] days in the SJL >= 1 h group, without significant difference. Logistic regression analysis showed that more than 1 h of SJL was a significant associated factor with severe menstrual symptom, independently of sleep duration and late chronotype. This study indicated that SJL was a significant factor associated with severe menstrual symptoms, suggesting the possibilities of association between circadian system and reproductive function among humans. AN - WOS:000456977400009 AU - Komada, Y. AU - Ikeda, Y. AU - Sato, M. AU - Kami, A. AU - Masuda, C. AU - Shibata, S. DA - Feb DO - 10.1080/07420528.2018.1533561 IS - 2 N1 - Komada, Yoko Ikeda, Yuko Sato, Makoto Kami, Azusa Masuda, Chika Shibata, Shigenobu Komada, Yoko/AAN-8342-2021 Komada, Yoko/0000-0002-0884-1555 1525-6073 PY - 2019 SN - 0742-0528 SP - 258-264 ST - Social jetlag and menstrual symptoms among female university students T2 - Chronobiology International TI - Social jetlag and menstrual symptoms among female university students UR - ://WOS:000456977400009 VL - 36 ID - 1954 ER - TY - JOUR AB - PURPOSE: Many children with spinal muscular atrophy (SMA) develop progressive spinal deformity, worsening already compromised pulmonary function and global spinal balance. Early results demonstrate that intrathecal administration of nusinersen, a recent FDA-approved drug, improves motor function and ventilator-free survival, necessitating preservation of intrathecal access when considering PSIF. The purpose of this study is to assess medium-term outcomes of a specialized approach for posterior spinal instrumentation and fusion (PSIF) to preserve intrathecal access in patients with SMA. METHODS: A retrospective review of patients with SMA undergoing PSIF at a single tertiary academic medical center during a 3-year period was completed. To facilitate intrathecal drug administration, the traditional approach to PSIF was modified to "skip" one or more intervertebral levels at the thoracolumbar junction. Clinical notes and radiographs were reviewed for postoperative outcomes including major coronal curve correction and complications, including loss of correction, hardware failure and surgical revision. RESULTS: Eight patients were identified, with a mean age of 12.7 ± 1.6 years and follow-up of 4 years. These patients had a mean preoperative major coronal curve of 56.4°, with mean curve correction of 35.2°. At follow-up, no patients experienced rod breakage, loss of correction, or postoperative chronic pain. Only one patient required revision surgery due to bony overgrowth at the skipped level after three and a half years. CONCLUSION: Implementing the skip construct approach for PSIF in patients with SMA allows for scoliosis correction without compromising intrathecal drug delivery. Follow-up at 4 years reveals no adverse clinical events, hardware failure or loss of correction. LEVEL OF EVIDENCE: IV. AD - Department of Pediatric Orthopaedic Surgery, Morgan Stanley Children's Hospital of New York Presbyterian, Columbia University Medical Center, ATTN: Michael Vitale, 3959 Broadway, CHONY 8-N, New York, NY, 10032-3784, USA. Department of Pediatric Orthopaedic Surgery, Morgan Stanley Children's Hospital of New York Presbyterian, Columbia University Medical Center, ATTN: Michael Vitale, 3959 Broadway, CHONY 8-N, New York, NY, 10032-3784, USA. mgv1@cumc.columbia.edu. AN - 32253736 AU - Konigsberg, M. W. AU - Matsumoto, H. AU - Ball, J. R. AU - Roye, B. D. AU - Vitale, M. G. DA - Oct DO - 10.1007/s43390-020-00107-3 DP - NLM ET - 2020/04/08 IS - 5 KW - Adolescent Disease Progression Drug Administration Routes Female Follow-Up Studies Humans Injections, Spinal Male Muscular Atrophy, Spinal/*complications/drug therapy/*surgery Oligonucleotides/administration & dosage Retrospective Studies Scoliosis/*etiology/*surgery Spinal Fusion/*instrumentation/*methods Treatment Outcome *Early onset scoliosis *Nusinersen *Posterior spinal fusion *Scoliosis *Spinal muscular atrophy LA - eng N1 - 2212-1358 Konigsberg, Matthew W Matsumoto, Hiroko Ball, Jacob R Roye, Benjamin D Vitale, Michael G Journal Article England Spine Deform. 2020 Oct;8(5):1093-1097. doi: 10.1007/s43390-020-00107-3. Epub 2020 Apr 6. PY - 2020 SN - 2212-134x SP - 1093-1097 ST - Skip constructs in spinal muscular atrophy: outcomes of a novel approach for posterior spinal instrumentation and fusion T2 - Spine Deform TI - Skip constructs in spinal muscular atrophy: outcomes of a novel approach for posterior spinal instrumentation and fusion VL - 8 ID - 4126 ER - TY - JOUR AB - Sleep problems are common in pediatric patients with chronic respiratory disorders. Nocturnal awakenings are frequent in children with asthma. Chronobiologic rhythms impact the pathophysiology of nocturnal asthma. Poor sleep quality can lead to impaired school performance, neurocognitive defects and attention problems in children. As lung function worsens sleep disruption becomes more prominent in patients with cystic fibrosis. Bronchopulmonary dyplasia has been associated with hypoxia during sleep. These infants have been reported to have reduced total sleep time, sleep fragmentation and reduced REM sleep. Nocturnal respiratory variations are exaggerated at night in children with sickle cell disease and the nocturnal hypoxia has been associated with painful crisis. Adenotonsillar hypertrophy with attendant obstructive sleep apnea worsen these episodes in sickle cell disease. In children with kyphoscoliosis hypoventilation at night worsens during REM sleep. Nocturnal hypoventilation generally precedes respiratory failure. Sleep-disordered breathing with excessive daytime sleepiness has been well described in pediatric neuromuscular disorders. Abnormal sleep patterns including sleep-disordered breathing occur in infants with apnea of prematurity and sudden infant death syndrome. Further research in this diverse group of sleep disorders in children exploring the pathophysiology and treatment is essential. AN - WOS:000212650000006 AU - Konnur, N. AU - Ghamande, S. A. DO - 10.2174/157339809790112483 IS - 4 N1 - Konnur, Neelam Ghamande, Shekhar A. Ghamande, Shekhar/M-4489-2019 Ghamande, Shekhar/0000-0001-6924-9494 1875-6387 PY - 2009 SN - 1573-398X SP - 220-224 ST - Sleep in Pediatric Pulmonary Diseases T2 - Current Respiratory Medicine Reviews TI - Sleep in Pediatric Pulmonary Diseases UR - ://WOS:000212650000006 VL - 5 ID - 2623 ER - TY - JOUR AB - BACKGROUND: Although previous research has demonstrated that patients with posttraumatic migraine (PTM) after concussion report more symptoms and cognitive deficits after injury than do those without PTM, it is not known whether these effects persist beyond the first week of injury or whether PTM predicts recovery time. PURPOSE: To determine whether PTM during the first week after injury predicts (1) cognitive impairment and symptoms in the second week after injury and (2) overall recovery time. STUDY DESIGN: Cohort study; Level of evidence, 2. METHODS: Participants were 138 male high school football players with a mean age of 15.96 years (SD, 1.18 years; range, 13-19 years). They were classified into 3 groups: PTM (headache, nausea, and photosensitivity or phonosensitivity), headache (headache without the other PTM symptoms), or no headache (no headache or PTM symptoms). The Immediate Post-concussion Assessment and Cognitive Test (ImPACT) was used to assess cognitive performance and symptoms at baseline, postinjury days 1-7, and postinjury days 8-14. Recovery time data were collected from medical records. RESULTS: The PTM group performed worse on verbal memory than did the headache group at 8-14 days after injury. The PTM group performed worse on visual memory, reaction time, and symptoms than did the other groups at 1-7 days and 8-14 days after injury. The PTM group was 7.3 times (95% confidence interval, 1.80-29.91) more likely to have protracted recovery (>20 days) than the no headache group and 2.6 times (95% confidence interval, 1.10-6.54) more likely than the headache group. CONCLUSION: Results suggest that PTM is associated with cognitive impairments and protracted recovery and that headache alone is not a good predictor of recovery. AD - Department of Orthopaedic Surgery/UPMC Sports Medicine Concussion Program, University of Pittsburgh, Pittsburgh, Pennsylvania 15203, USA. akontos@pitt.edu AN - 23698389 AU - Kontos, A. P. AU - Elbin, R. J. AU - Lau, B. AU - Simensky, S. AU - Freund, B. AU - French, J. AU - Collins, M. W. DA - Jul DO - 10.1177/0363546513488751 DP - NLM ET - 2013/05/24 IS - 7 KW - Adolescent Cognition Disorders/*etiology/*physiopathology Forecasting Humans Male Migraine Disorders/*etiology/psychology Post-Concussion Syndrome/*complications/psychology Prospective Studies *Recovery of Function Risk Factors concussion headache migraine mild traumatic brain injury sports symptoms LA - eng N1 - 1552-3365 Kontos, Anthony P Elbin, R J Lau, Brian Simensky, Steven Freund, Brin French, Jonathan Collins, Michael W Journal Article United States Am J Sports Med. 2013 Jul;41(7):1497-504. doi: 10.1177/0363546513488751. Epub 2013 May 22. PY - 2013 SN - 0363-5465 SP - 1497-504 ST - Posttraumatic migraine as a predictor of recovery and cognitive impairment after sport-related concussion T2 - Am J Sports Med TI - Posttraumatic migraine as a predictor of recovery and cognitive impairment after sport-related concussion VL - 41 ID - 3685 ER - TY - JOUR AB - BACKGROUND: The highest prevalence of migraine is detected among people who are of working age. The aim of this study was to assess the burden of migraine in an occupational health care setting using real world data collected as a part of routine clinical practice. METHODS: This retrospective register study included migraineurs using occupational health care at the private health care provider Terveystalo. An age and gender matched control population was established for comparison. Electronic medical records were assessed for overall and migraine related health care visits, sick-leaves and comorbidities. Stratification to acute and prophylactic treatment groups along with prophylactic treatment lines was based on prescriptions. RESULTS: Among the 369,383 individuals in the study cohort, 7.4% women and 2.1% men were identified having a diagnosis of migraine. Prophylactic medication was prescribed to 13% of migraine patients and exclusively acute medication to 37%. Although migraine related visits and sick-leave days were significantly lower than overall visits or sick-leave days, both increased by prophylactic treatment line. The number of visits rose from 13.8 to 26.2 and sick-leave days from 16.8 to 30.4 per patient-year, in those without prophylaxis vs. ≥3 prophylactic treatments. Moreover, migraine patients had 1.7-fold increase in visits and 1.8-fold increase in sick leave days on average per patient-year, when compared to the control population. Depression and anxiety were 1.8-fold more common among patients with migraine, and the frequency also increase by treatment line. CONCLUSIONS: Migraine burden increased by each failed treatment line and was associated with increased comorbidity. In addition, migraine patients had significantly higher extent of visits and sick-leave days as well as extent of comorbidities when compared to their age- and gender-matched counterparts. AD - Novartis Finland Oy, Espoo, Finland. Terveystalo Biobank Finland, Humalistonkatu 7B, 20100, Turku, Finland. Medaffcon Oy, Espoo, Finland. Novartis AB, Kista, Sweden. Terveystalo Biobank Finland, Humalistonkatu 7B, 20100, Turku, Finland. Markku.Nissila@terveystalo.com. AN - 30755160 AU - Korolainen, M. A. AU - Kurki, S. AU - Lassenius, M. I. AU - Toppila, I. AU - Costa-Scharplatz, M. AU - Purmonen, T. AU - Nissilä, M. C2 - PMC6734482 DA - Feb 12 DO - 10.1186/s10194-019-0964-5 DP - NLM ET - 2019/02/14 IS - 1 KW - Adolescent Adult Aged Anxiety Disorders/diagnosis/epidemiology/therapy Cohort Studies Comorbidity *Cost of Illness Depressive Disorder/diagnosis/epidemiology/therapy Female Finland/epidemiology Follow-Up Studies Humans Male Middle Aged Migraine Disorders/diagnosis/*epidemiology/*therapy Occupational Health/*trends *Patient Acceptance of Health Care Prevalence Registries Retrospective Studies Sick Leave/*trends Young Adult Absenteeism Comorbidities Disease burden Migraine Prophylactic treatment Treatment lines no conflicts of interest to declare, IT no conflicts of interest to declare. LA - eng N1 - 1129-2377 Korolainen, Minna A Kurki, Samu Lassenius, Mariann I Toppila, Iiro Costa-Scharplatz, Madlaina Purmonen, Timo Nissilä, Markku not applicable/Novartis Finland Oy/ Journal Article J Headache Pain. 2019 Feb 12;20(1):13. doi: 10.1186/s10194-019-0964-5. PY - 2019 SN - 1129-2369 (Print) 1129-2369 SP - 13 ST - Burden of migraine in Finland: health care resource use, sick-leaves and comorbidities in occupational health care T2 - J Headache Pain TI - Burden of migraine in Finland: health care resource use, sick-leaves and comorbidities in occupational health care VL - 20 ID - 3772 ER - TY - JOUR AB - OBJECTIVE: We aimed to review the literature regarding epidemiology of functional abdominal pain disorders in children and to assess its geographic, gender and age distribution including associated risk factors of developing functional abdominal pain. METHODS: The Cochrane Library, MEDLINE, EMBASE, CINAHL and PsychInfo databases were systematically searched up to February 2014. Study selection criteria included: (1) studies of birth cohort, school based or general population samples (2) containing data concerning epidemiology, prevalence or incidence (3) of children aged 4-18 years (4) suffering from functional abdominal pain. Quality of studies was rated by a self-made assessment tool. A random-effect meta-analysis model was used to estimate the prevalence of functional abdominal pain in childhood. RESULTS: A total of 58 articles, including 196,472 children were included. Worldwide pooled prevalence for functional abdominal pain disorders was 13.5% (95% CI 11.8-15.3), of which irritable bowel syndrome was reported most frequently (8.8%, 95% CI 6.2-11.9). The prevalence across studies ranged widely from 1.6% to 41.2%. Higher pooled prevalence rates were reported in South America (16.8%) and Asia (16.5%) compared to Europe (10.5%). And a higher pooled prevalence was reported when using the Rome III criteria (16.4%, 95% CI 13.5-19.4). Functional abdominal pain disorders are shown to occur significantly more in girls (15.9% vs. 11.5%, pooled OR 1.5) and is associated with the presence of anxiety and depressive disorders, stress and traumatic life events. CONCLUSION: Functional abdominal pain disorders are a common problem worldwide with irritable bowel syndrome as most encountered abdominal pain-related functional gastrointestinal disorder. Female gender, psychological disorders, stress and traumatic life events affect prevalence. AD - Department of Pediatric Gastroenterology and Nutrition, Emma's Children's Hospital Academic Medical Center, Amsterdam, The Netherlands. AN - 25992621 AU - Korterink, J. J. AU - Diederen, K. AU - Benninga, M. A. AU - Tabbers, M. M. C2 - PMC4439136 DO - 10.1371/journal.pone.0126982 DP - NLM ET - 2015/05/21 IS - 5 KW - Abdominal Pain/*epidemiology/*physiopathology Child Geography Humans Prevalence Reproducibility of Results Surveys and Questionnaires LA - eng N1 - 1932-6203 Korterink, Judith J Diederen, Kay Benninga, Marc A Tabbers, Merit M Journal Article Meta-Analysis PLoS One. 2015 May 20;10(5):e0126982. doi: 10.1371/journal.pone.0126982. eCollection 2015. PY - 2015 SN - 1932-6203 SP - e0126982 ST - Epidemiology of pediatric functional abdominal pain disorders: a meta-analysis T2 - PLoS One TI - Epidemiology of pediatric functional abdominal pain disorders: a meta-analysis VL - 10 ID - 3912 ER - TY - JOUR AB - Objectives:The aim of the present study was to compare effects of 10 weeks of yoga therapy (YT) and standard medical care (SMC) on abdominal pain and quality of life (QoL) in children with abdominal pain-related functional gastrointestinal disorders (AP-FGIDs).Methods:Sixty-nine patients, ages 8 to 18 years, with AP-FGIDs, were randomized to SMC complemented with YT or SMC alone. YT is a mixture of yoga poses, meditation, and relaxation exercises and was given once a week in group sessions. SMC consisted of education, reassurance, dietary advice, and fibers/mebeverine, if necessary. Pain intensity (pain intensity score [PIS] 0-5) and frequency (pain frequency score [PFS] 0-4) were scored in a pain diary, and QoL was measured with KIDSCREEN-27. Follow-up was 12 months. Treatment response was defined as 50% reduction of weekly pain scores.Results:At 1-year follow-up, treatment response was accomplished in 58% of the YT group and in 29% of the control group (P=0.01); no significant differences for other time points were found. YT, and not SMC, resulted in a significant reduction of PIS (P<0.01) and PFS (P<0.01) after 12 months. During the study, however, YT was not significantly superior compared with SMC. Subanalyses for time points demonstrated a significant greater reduction of PIS at 12 months in favor of YT. No differences were found for QoL. YT was more effective in the reduction of reported monthly school absence (P=0.03).Conclusion:At 1-year follow-up, YT in addition to standard care was superior compared with SMC according to treatment success, PIS, and reduction of school absence. YT, however, was not significantly more effective in improving PFS or QoL, compared with SMC. AN - WOS:000386350200018 AU - Korterink, J. J. AU - Ockeloen, L. E. AU - Hilbink, M. AU - Benninga, M. A. AU - Deckers-Kocken, J. M. DA - Nov DO - 10.1097/mpg.0000000000001230 IS - 5 N1 - Korterink, Judith J. Ockeloen, Lize E. Hilbink, Mirrian Benninga, Marc A. Deckers-Kocken, Judith M. 1536-4801 PY - 2016 SN - 0277-2116 SP - 481-487 ST - Yoga Therapy for Abdominal Pain-Related Functional Gastrointestinal Disorders in Children: A Randomized Controlled Trial T2 - Journal of Pediatric Gastroenterology and Nutrition TI - Yoga Therapy for Abdominal Pain-Related Functional Gastrointestinal Disorders in Children: A Randomized Controlled Trial UR - ://WOS:000386350200018 VL - 63 ID - 2137 ER - TY - JOUR AB - Background: In addition to the urinary abnormalities, symptoms of left renal vein entrapment between the aorta and superior mesenteric artery (left renal vein entrapment syndrome, LRVES) may include abdominal and flank pain as well as chronic fatigue. We investigated various LRVES symptoms in this study. Methods: In 53 pediatric LRVES patients treated at our department, 22 had a score of 5 points or higher on orthostasis. Initial evaluation of LRVES by abdominal ultrasonography showed a stenotic-to-prestenotic vein diameter ratio of 0.2 or less. Definitive diagnosis was made by computed tomography and magnetic resonance angiography. Cortisol, catecholamine (CA), and brain natriuretic peptide (BNP) were also measured. Results: The frequency of LRVES was 2.5 times higher in girls than in boys. Low or very low body mass indexes were seen in both sexes. The most common initial finding was urine abnormalities, followed by dizziness and malaise. In 6 patients, orthostasis precluded school attendance. Ten patients had orthostasis scores above 12. Patients unable to attend school had either low levels of plasma or urinary cortisol. Midodrine significantly decreased orthostasis scores. Some patients required treatment with fludrocortisone. Plasma CA, renin, and BNP levels were all normal. Conclusions: Locally excessive venous pressure may cause reversible adrenal dysfunction with transitory Addisonian symptoms. Children with cryptogenic malaise or severe orthostasis should be evaluated for LRVES. World J Pediatr 2012;8(2):116-122 AN - WOS:000303964400003 AU - Koshimichi, M. AU - Sugimoto, K. AU - Yanagida, H. AU - Fujita, S. AU - Miyazawa, T. AU - Sakata, N. AU - Okada, M. AU - Takemura, T. DA - May DO - 10.1007/s12519-012-0349-1 IS - 2 N1 - Koshimichi, Machiko Sugimoto, Keisuke Yanagida, Hidehiko Fujita, Shinsuke Miyazawa, Tomoki Sakata, Naoki Okada, Mitsuru Takemura, Tsukasa 1867-0687 PY - 2012 SN - 1708-8569 SP - 116-122 ST - Newly-identified symptoms of left renal vein entrapment syndrome mimicking orthostatic disturbance T2 - World Journal of Pediatrics TI - Newly-identified symptoms of left renal vein entrapment syndrome mimicking orthostatic disturbance UR - ://WOS:000303964400003 VL - 8 ID - 2437 ER - TY - JOUR AB - Background Nausea frequently co-exists with functional abdominal pain disorders (FAPDs) and may be linked to a higher disease burden. This study aimed to prospectively compare multisystem symptoms, quality of life, and functioning in FAPDs with and without nausea. Methods Adolescents ages 11-18 years fulfilling Rome III criteria for a FAPD were grouped by the presence or absence of chronic nausea. Subjects completed validated instruments assessing nausea (Nausea Profile Questionnaire = NPQ), quality of life (Patient-Reported Outcome Measurement Information System), functioning (Functional Disability Inventory), and anxiety (State-Trait Anxiety Inventory for Children). Group comparisons were performed for instruments, multisystem symptoms, school absences, and clinical diagnoses. Key Results A total of 112 subjects were included; 71% reported chronic nausea. Patients with Nausea compared to No Nausea had higher NPQ scores (P <= 0.001), worse quality of life (P = 0.004), and greater disability (P = 0.02). State and trait anxiety scores were similar (P = 0.57, P = 0.25). A higher NPQ score correlated with poorer quality of life, more disability, and higher anxiety. Specific comorbidities were more common in Nausea vs No Nausea group: dizziness (81% vs 41%; P <= 0.001), concentrating difficulties (68% vs 27%; P <= 0.001), chronic fatigue (58% vs 20%; P = 0.01), and sleep disturbances (73% vs 48%; P = 0.02). The Nausea group reported more school absences (P = 0.001) and more commonly met criteria for functional dyspepsia (P = 0.034). Conclusion and Inferences Nausea co-existing with FAPDs is associated with a higher extra-intestinal symptom burden, worse quality of life, and impaired functioning in children. Assessing and targeting nausea therapeutically is essential to improve outcomes in FAPDs. AN - WOS:000474293400015 AU - Kovacic, K. AU - Kapavarapu, P. K. AU - Sood, M. R. AU - Li, B. U. K. AU - Nugent, M. AU - Simpson, P. AU - Miranda, A. C7 - e13595 DA - Jul DO - 10.1111/nmo.13595 IS - 7 N1 - Kovacic, Katja Kapavarapu, Prasanna K. Sood, Manu R. Li, B. U. K. Nugent, Melodee Simpson, Pippa Miranda, Adrian Kovacic, Katja/0000-0002-2520-7396 1365-2982 PY - 2019 SN - 1350-1925 ST - Nausea exacerbates symptom burden, quality of life, and functioning in adolescents with functional abdominal pain disorders T2 - Neurogastroenterology and Motility TI - Nausea exacerbates symptom burden, quality of life, and functioning in adolescents with functional abdominal pain disorders UR - ://WOS:000474293400015 VL - 31 ID - 1902 ER - TY - JOUR AB - Objectives:The aim of the study was to determine the prevalence of nausea in pediatric patients with pain-associated functional gastrointestinal disorders (FGIDs), examine the effect on social and school functioning, and examine the applicability of pediatric Rome III criteria.Methods:A total of 221 pediatric patients (6-18 years of age) with chronic abdominal pain prospectively completed a demographic, history, and gastrointestinal symptom questionnaire adapted from the Questionnaire on Pediatric Gastrointestinal Symptoms (QPGS). The 6-item, revised Pediatric Migraine Disability Assessment Score tool was used to assess the effect of symptoms on school, home, and social disability. Rome III criteria were applied to all subjects.Results:A total of 183 patients with pain and nausea for a minimum of 2 months were identified. Ninety-six patients were studied after excluding those with vomiting and/or organic disease. Among these, 53% had nausea at least 2 times per week and 28% experienced daily nausea. Frequency of nausea was significantly correlated with poor school and social functioning, and uniquely predicted social disability beyond pain. Although 87% met adult Rome criteria for functional dyspepsia, only 29% met corresponding pediatric Rome criteria. Additionally, 22% met the criteria for irritable bowel syndrome (IBS)-diarrhea, 13% for IBS-constipation, 13% for abdominal migraine, and 31% were classified as having functional abdominal pain. Pediatric IBS-diarrhea and IBS-constipation overlapped in 5% of patients.Conclusions:Nausea is a prevalent symptom in patients with pain-associated FGIDs and correlates with poor school and social functioning. There is substantial overlap among FGIDs in children with nausea. AN - WOS:000326745200016 AU - Kovacic, K. AU - Williams, S. AU - Li, B. U. K. AU - Chelimsky, G. AU - Miranda, A. DA - Sep DO - 10.1097/MPG.0b013e3182964203 IS - 3 N1 - Kovacic, Katja Williams, Sara Li, B. U. K. Chelimsky, Gisela Miranda, Adrian 1536-4801 PY - 2013 SN - 0277-2116 SP - 311-315 ST - High Prevalence of Nausea in Children With Pain-Associated Functional Gastrointestinal Disorders: Are Rome Criteria Applicable? T2 - Journal of Pediatric Gastroenterology and Nutrition TI - High Prevalence of Nausea in Children With Pain-Associated Functional Gastrointestinal Disorders: Are Rome Criteria Applicable? UR - ://WOS:000326745200016 VL - 57 ID - 2355 ER - TY - JOUR AB - In this article we outline the framework our consultation-liaison team has developed for interviewing families whose children present with medically unexplained symptoms. The framework was developed over many years in the context of our work with a large number of families, who collectively taught us to be more sensitive with regard to the experience of such families in the medical system, and who reacted strongly when we moved prematurely to the use of psychological language or to questions about family relationships or emotional functioning. Throughout the interview we maintain a focus on the body: the family history of illness and, in particular, the story of the child's symptoms. We take a detailed, temporally ordered history of the symptom and ask for collateral information - family illness, family life events, events at school, family emotional responses - all in relation to the story of the symptoms. In the assessment interview and in our work in general, we focus on the body. We move very carefully and very slowly from the physical to the psychological, from talking about the body to talking about relationships and about the mind. AN - WOS:000336720000006 AU - Kozlowska, K. AU - English, M. AU - Savage, B. DA - Apr DO - 10.1177/1359104512447314 IS - 2 N1 - Kozlowska, Kasia English, Margaret Savage, Blanche 1461-7021 PY - 2013 SN - 1359-1045 SP - 224-245 ST - Connecting body and mind: The first interview with somatising patients and their families T2 - Clinical Child Psychology and Psychiatry TI - Connecting body and mind: The first interview with somatising patients and their families UR - ://WOS:000336720000006 VL - 18 ID - 2377 ER - TY - JOUR AB - In Part 2, we describe three cases implementing our mind-body, family-based, multimodal rehabilitation approach for treating children and adolescents presenting with medically unexplained symptoms. For each child and family, treatment interventions were selected and implemented, simultaneously or sequentially. In a cohort of 100 consecutively referred children, 56 suffered from, and were treated for, significant physical or chronic school absenteeism. Thirty-five of these children (63%) recovered fully, 10 (18%) had a relapsing course, 7 (12.5%) had chronic symptoms, and 4 (7%) were lost to follow-up. These outcomes suggest that mind-body multimodal rehabilitation is a successful, cost-effective model of treatment. AN - WOS:000317830400003 AU - Kozlowska, K. AU - English, M. AU - Savage, B. AU - Chudleigh, C. AU - Davies, F. AU - Paull, M. AU - Elliot, A. AU - Jenkins, A. DA - May DO - 10.1080/01926187.2012.677723 IS - 3 N1 - Kozlowska, Kasia English, Margaret Savage, Blanche Chudleigh, Catherine Davies, Fiona Paull, Marilyn Elliot, Alison Jenkins, Amanda Jenkins, Alicia/N-2482-2015 1521-0383 PY - 2013 SN - 0192-6187 SP - 212-231 ST - Multimodal Rehabilitation: A Mind-Body Family-Based Intervention for Children and Adolescents Impaired by Medically Unexplained Symptoms. Part 2: Case Studies and Outcomes T2 - American Journal of Family Therapy TI - Multimodal Rehabilitation: A Mind-Body Family-Based Intervention for Children and Adolescents Impaired by Medically Unexplained Symptoms. Part 2: Case Studies and Outcomes UR - ://WOS:000317830400003 VL - 41 ID - 2368 ER - TY - JOUR AB - Recurring pain in children and adolescents can have a negative impact on health and well-being. This study investigates recurring headache, abdominal pain, and back pain in children and adolescents in Thuringia. Data is based on a representative sub-sample from the federal state module Thuringia (2010-2012, naEuro= 4096, 3-17 years), carried out in KiGGS wave 1 (first follow-up interview of the "German Health Interview and Examination Survey for Children and Adolescents"). The 3aEuromonth prevalence of recurrent headache, abdominal pain, and back pain is reported according to socio-demographic factors and is compared with the prevalence for the whole of Germany. In addition, possible associated factors of recurring headache, abdominal pain, and back pain in the previous 3 months are analyzed. Results for Thuringia show that 3aEuro to 10-year-old children were most frequently affected by recurrent abdominal pain (girls: 24.1%; boys: 16.7%), while 11- to 17-year-old adolescents were most frequently affected by recurrent headaches (girls: 36.8%; boys: 20.6%). There were isolated socio-economic differences in the 3aEuromonth prevalences of recurrent headache and back pain to the detriment of the low status group. Compared to peers in the whole of Germany, girls and boys in Thuringia did not report headache, abdominal pain, and back pain in the previous 3 months more frequently. The investigated associated factors-fair to very poor self-rated health, emotional problems such as anxiety and depressive symptoms, chronic diseases and other health complaints, migraine, use of a general medical practice, as well as practices for orthopedics and neurology, and in-patient treatment at a hospital-were positively related to the 3aEuromonth prevalence of recurrent headache, abdominal pain, and back pain. Overall, the results confirm that recurring pain is a common phenomenon in childhood and adolescents and, therefore, underline the public health relevance of pain in this young age group. AN - WOS:000429329700004 AU - Krause, L. AU - Mauz, E. DA - Apr DO - 10.1007/s00482-018-0280-z IS - 2 N1 - Krause, L. Mauz, E. 1432-2129 PY - 2018 SN - 0932-433X SP - 105-114 ST - Headache, abdominal pain, and back pain in children and adolescents in Thuringia. Representative results of a regional module study in KiGGS wave 1 T2 - Schmerz TI - Headache, abdominal pain, and back pain in children and adolescents in Thuringia. Representative results of a regional module study in KiGGS wave 1 UR - ://WOS:000429329700004 VL - 32 ID - 2025 ER - TY - JOUR AB - Background Pain not only causes suffering in children and adolescents, but also leads to school absenteeism, medication intake, medical treatment, and an increased risk of recurrent pain in adulthood. Objectives Based on data from the nationwide German Health Interview and Examination Survey for Children and Adolescents (KiGGS Wave 2, 2014-2017), the 3-month prevalence of recurrent headache, abdominal and back pain in girls and boys is reported, and is compared with the prevalence from the KiGGS baseline survey (2003-2006). The consequences of recurrent headache were also explored. Materials and methods Data from >11,000 participants (KiGGS Wave 2) and from >12,000 (KiGGS baseline) participants aged between 3 and 17 years were analyzed. For 3- to 10-year-olds, parents/guardians answered the questions, while 11- to 17-year-olds provided information themselves. Results In 3- to 10-year-olds, recurrent abdominal pain was most prevalent, affecting one third of girls and one quarter of boys. Headache was the most frequent type of pain in 11- to 17-year-olds, affecting almost every second girl and about every third boy. The 3-month prevalence of recurrent headache, abdominal and back pain has increased in girls and boys, especially in the age groups 7 to 10 years and 11 to 13 years. Among recurrent headache sufferers, adolescents take medication almost twice as often as children. Conclusions Headache, abdominal, and back pain are still and with increasing prevalence very common symptoms in children and adolescents in Germany. Their prevention requires a holistic view of children's health in the psychosocial living environment, and healthcare context. AN - WOS:000487053700004 AU - Krause, L. AU - Sarganas, G. AU - Thamm, R. AU - Neuhauser, H. DA - Oct DO - 10.1007/s00103-019-03007-8 IS - 10 N1 - Krause, Laura Sarganas, Giselle Thamm, Roma Neuhauser, Hannelore 1437-1588 Si PY - 2019 SN - 1436-9990 SP - 1184-1194 ST - Headache, abdominal and back pain in children and adolescents in Germany Results from KiGGS Wave 2 and trends T2 - Bundesgesundheitsblatt-Gesundheitsforschung-Gesundheitsschutz TI - Headache, abdominal and back pain in children and adolescents in Germany Results from KiGGS Wave 2 and trends UR - ://WOS:000487053700004 VL - 62 ID - 1881 ER - TY - JOUR AB - The study considered the prevalence of experienced stomach pain in a nationwide random sample of 2161 Icelandic 11-12 and 15-16-year-old school children. It found an 18.4% prevalence of ''at least weekly'' stomach pain and a 53.4% overall prevalence. The prevalence of stomach pain was significantly higher among younger children (P less than or equal to 0.001). Higher prevalence (P less than or equal to 0.001) of stomach pain was seen in girls in the overall sample and the gender difference was significant in both age groups. No overall class or residential differences were detected. However, the findings suggest some age-related links between social status and the experience of stomach pain. The frequency of stomach pain was moderately and significantly associated with medication use. The theoretical and clinical implications of the results are briefly discussed. Conclusion The high prevalence of frequent stomach pain found in this study calls for future research documenting further the epidemiology of stomach pain and various bio-psycho-social factors related to the experience and extent of this pain in school children. AN - WOS:A1996VN80600014 AU - Kristjansdottir, G. DA - Nov DO - 10.1007/bf02282891 IS - 11 N1 - Kristjansdottir, G Kristjansdottir, Gudrun/A-1737-2008 Kristjansdottir, Gudrun/0000-0002-1616-7687 PY - 1996 SN - 0340-6199 SP - 981-983 ST - Sociodemographic differences in the prevalence of self-reported stomach pain in school children T2 - European Journal of Pediatrics TI - Sociodemographic differences in the prevalence of self-reported stomach pain in school children UR - ://WOS:A1996VN80600014 VL - 155 ID - 2918 ER - TY - JOUR AB - This study examined physical, behavioral and social factors associated with schoolchildren's back pain. Factors associated with back pain were also identified using a stepwise regression method. The study was based on a self-administered questionnaire survey of a random national sample of 2173 Icelandic 11-12 and 15-16-y-old schoolchildren. It found that older subjects tended to report back pain more frequently than younger children. Back pain showed significant associations with different aspects of physical condition such as chronic health conditions, tiredness and physical fitness. A number of behavioral factors including participation in sports, television viewing, eating habits and smoking also had a relationship with back pain. Finally, children with lower social support were more likely to experience back pain. CONCLUSION: Overall, four major factors (age, morning tiredness, eating habits and parental support) emerged as factors associated with back pain in the study subjects. These results highlighted the roles of lifestyle and social factors in the experience of back pain in schoolchildren. AD - University of Iceland, Faculty of Nursing, Eiriksgata 34, IS-101 Reykjavik, Iceland. gkrist@hi.is AN - 12200915 AU - Kristjansdottir, G. AU - Rhee, H. DO - 10.1080/08035250213208 DP - NLM ET - 2002/08/31 IS - 7 KW - Adolescent Back Pain/epidemiology/*prevention & control Child Female Health Behavior Humans Iceland/epidemiology Life Style Male Risk Factors Social Support Socioeconomic Factors LA - eng N1 - Kristjansdottir, G Rhee, H Journal Article Research Support, Non-U.S. Gov't Norway Acta Paediatr. 2002;91(7):849-54. doi: 10.1080/08035250213208. PY - 2002 SN - 0803-5253 (Print) 0803-5253 SP - 849-54 ST - Risk factors of back pain frequency in schoolchildren: a search for explanations to a public health problem T2 - Acta Paediatr TI - Risk factors of back pain frequency in schoolchildren: a search for explanations to a public health problem VL - 91 ID - 3826 ER - TY - JOUR AB - ObjectiveThe objective of this secondary analysis of results from a previously published trial () in chronic migraine in children and adolescents was to examine if participants who received cognitive behavioral therapy and amitriptyline reached a greater level of reduction in headache frequency that no longer indicated a recommendation for preventive treatment as compared to those who received headache education and amitriptyline. BackgroundChronic migraine negatively affects children's home, school, and social activities. Preventive medication therapy is suggested for 5 or more headaches per month. Reduction to one headache day per week or less may suggest that preventive treatment is no longer indicated and provide a clinically relevant outcome for treatment efficacy and patient care. MethodsRandomized study participants (N=135) kept a daily record of their headache frequency during 20 weeks of treatment and during a 1 year follow-up period. Baseline headache frequency was determined at the end of a 28 day screening period. Post treatment frequency was determined at 20 weeks (N=128 completed) and post treatment follow-up was measured 12 months later (N=124 completed). A chi-square test of independence was conducted by treatment group and by time point to determine group differences in the proportion of headache days experienced. ResultsAt 20 weeks (post treatment), 47% of the cognitive behavioral therapy plus amitriptyline group had 4 headache days per month compared to 20% of the headache education plus amitriptyline group, (P=.0011), and 32% of the cognitive behavioral therapy plus amitriptyline group had 3 headache days per month at 20 weeks compared to 16% of the headache education plus amitriptyline group, (P=.0304). At the month 12 follow-up, 72% of the cognitive behavioral therapy plus amitriptyline group had 4 headache days per month compared to 52% of the headache education plus amitriptyline group, (P=.0249), and 61% of the cognitive behavioral therapy plus amitriptyline group had 3 headache days per month at their month 12 follow-up compared to 40% of the headache education plus amitriptyline group, (P=.0192). ConclusionsParticipants who received cognitive behavioral therapy and amitriptyline were more likely than participants who received headache education plus amitriptyline to reach the clinically meaningful outcome of less than or equal to 4 headache days per month at both time points. These results may help inform what treatment outcomes are possible for children and adolescents suffering from chronic migraine and provides further evidence for behavioral treatment to be considered as a key part of a first line treatment regimen. AN - WOS:000374696100008 AU - Kroner, J. W. AU - Hershey, A. D. AU - Kashikar-Zuck, S. M. AU - LeCates, S. L. AU - Allen, J. R. AU - Slater, S. K. AU - Zafar, M. AU - Kabbouche, M. A. AU - O'Brien, H. L. AU - Shenk, C. E. AU - Rausch, J. R. AU - Van Diest, A. M. K. AU - Powers, S. W. DA - Apr DO - 10.1111/head.12795 IS - 4 N1 - Kroner, John W. Hershey, Andrew D. Kashikar-Zuck, Susmita M. LeCates, Susan L. Allen, Janelle R. Slater, Shalonda K. Zafar, Marium Kabbouche, Marielle A. O'Brien, Hope L. Shenk, Chad E. Rausch, Joseph R. Van Diest, Ashley M. Kroon Powers, Scott W. Hershey, Andrew D./K-1245-2019; Rausch, Joseph R/E-8107-2018; O'Brien, Hope/AAZ-9717-2020 Hershey, Andrew D./0000-0002-1598-7536; Powers, Scott/0000-0002-5348-9650; Kroner, John/0000-0003-1674-9609 1526-4610 PY - 2016 SN - 0017-8748 SP - 711-716 ST - Cognitive Behavioral Therapy plus Amitriptyline for Children and Adolescents with Chronic Migraine Reduces Headache Days to 4 Per Month T2 - Headache TI - Cognitive Behavioral Therapy plus Amitriptyline for Children and Adolescents with Chronic Migraine Reduces Headache Days to 4 Per Month UR - ://WOS:000374696100008 VL - 56 ID - 2177 ER - TY - JOUR AB - An abundance of studies have consistently shown that headache is the most prevalent pain in children and adolescents. Weekly headache is experienced by more than 10 % and is distinctly more frequent in girls. The number of headache-affected youths with high disability is lower than expected (similar to 4 %). Headache is associated with pain in other body sites, thus multiple pain is experienced more often than isolated headache. Various somatic symptoms and even chronic diseases are also correlated with headache. Headache in parents carries a high risk of also occurring in their children. Various other psychosocial factors such as dysfunctional psychological traits are closely linked with headache, the most prominent being internalizing symptoms. However, externalizing symptoms also correlate with headache. Pain catastrophizing, as well as somatosensory amplification and anxiety sensitivity, have been shown to characterize individuals with headache. Features of the social environment, such as life events, school, as well as family stressors and socioeconomic parameters, are among the risk factors. Psychological interventions such as biofeedback, relaxation, and cognitive-behavioral training have proved their efficacy in headache treatment according to several meta-analyses. The latter has also been conducted in group settings and more recently in self-management focused trainings using electronic media. They mainly aim at the prevention of further headache episodes. The goal of this training is the strengthening of self-efficacy beliefs and active coping strategies. It is proposed that these competencies could contribute to the successful long-term prevention of an adverse course of headache into adulthood. AN - WOS:000339899000004 AU - Kroner-Herwig, B. DA - Aug DO - 10.1007/s00103-014-1999-z IS - 8 N1 - Kroener-Herwig, B. 1437-1588 PY - 2014 SN - 1436-9990 SP - 928-934 ST - Headache in children and adolescents. Epidemiology, biopsychosocial correlates, and psychological treatment approaches T2 - Bundesgesundheitsblatt-Gesundheitsforschung-Gesundheitsschutz TI - Headache in children and adolescents. Epidemiology, biopsychosocial correlates, and psychological treatment approaches UR - ://WOS:000339899000004 VL - 57 ID - 2294 ER - TY - JOUR AB - A group study on the comparative efficacy of EMG biofeedback and progressive relaxation is presented. Sixteen children aged between 8 and 14 years with chronic tension headache and combined headache participated in the study. Six sessions of relaxation training and 12 (shorter) biofeedback sessions were held with each child. Both treatments had excellent results, which were apparent directly after training. All but one child benefited to a clinically significant extent from the treatment, with a reduction of more than 50% in headache frequency. Other variables indicate further positive effects of treatment (e.g., medication consumption, absence from school). After 6 months of follow-up the children treated by relaxation had achieved event further reductions in headache activity. Suggestions for further improvement in the clinical and economic efficiency of treatment formats are presented, and perspectives for future research are discussed. AD - Institut für Klinische Psychologie, Universität Düsseldorf, Universitätsstraße 1, W-4000, Düsseldorf 1, Bundesrepublik Deutschland. AN - 18415618 AU - Kröner-Herwig, B. AU - Plump, U. AU - Pothmann, R. DA - Jun DO - 10.1007/bf02528129 DP - NLM ET - 1992/06/01 IS - 2 LA - ger N1 - Kröner-Herwig, B Plump, U Pothmann, R English Abstract Journal Article Germany Schmerz. 1992 Jun;6(2):121-7. doi: 10.1007/BF02528129. OP - Progressive Relaxation und EMG-Biofeedback in der Therapie von chronischem Kopfschmerz bei Kindern : Ergebnisse einer explorativen Studie. PY - 1992 SN - 0932-433X (Print) 0932-433x SP - 121-7 ST - [Progressive relaxation and EMG biofeedback in the treatment of chronic headache in children. Results of an explorative study.] T2 - Schmerz TI - [Progressive relaxation and EMG biofeedback in the treatment of chronic headache in children. Results of an explorative study.] VL - 6 ID - 4201 ER - TY - JOUR AB - OBJECTIVES: To investigate the influence of environmental factors on chronic prostatitis-like symptoms among young men in a community. METHODS: Of 28,841 men aged 20 years dwelling in the community, a total of 16,321 men (response rate 56.6%) were included in this study. The National Institutes of Health Chronic Prostatitis Symptom Index was used to identify men with chronic prostatitis-like symptoms. The questionnaire also queried sociodemographic characteristics. The Korean Meteorological Administration provided information on the weather of the community. We determined the risk factors of chronic prostatitis-like symptoms among these environmental factors using univariate and multivariate analyses. RESULTS: Six percent of the men were identified as having significant prostatitis-like symptoms (perineal and/or ejaculatory pain and a total pain score of 4 or greater). The univariate logistic regression analysis indicated that education level, average duration of sunlight, and average temperature were risk factors for chronic prostatitis-like symptoms. As these variables increased, the scores of chronic prostatitis-like symptoms decreased. In the multivariate model used, the likelihood of chronic prostatitis-like symptoms varied by the final educational level, with middle school and high school graduates having 1.8 and 1.4-fold higher odds, respectively, than men attending college. In the same model, the average duration of sunlight was also an independent risk factor of chronic prostatitis-like symptoms (odds ratio 0.85; 95% confidence interval 0.77 to 0.95; P = 0.003), but the average temperature lost statistical significance. CONCLUSIONS: Our findings suggest that the community-based prevalence of chronic prostatitis-like symptoms may be high in young men. Higher education and a longer time in sunlight were associated with a decreased likelihood of chronic prostatitis-like symptoms. AD - Department of Urology, Military Manpower Administration, Taejeon, South Korea. AN - 11744444 AU - Ku, J. H. AU - Kim, M. E. AU - Lee, N. K. AU - Park, Y. H. DA - Dec DO - 10.1016/s0090-4295(01)01424-8 DP - NLM ET - 2001/12/18 IS - 6 KW - Adult Analysis of Variance Chronic Disease Cross-Sectional Studies Educational Status Ejaculation Humans Korea/epidemiology Male Odds Ratio Pain/etiology Perineum Prevalence Prostatitis/complications/*epidemiology Regression Analysis *Seasons Socioeconomic Factors LA - eng N1 - 1527-9995 Ku, J H Kim, M E Lee, N K Park, Y H Journal Article United States Urology. 2001 Dec;58(6):853-8. doi: 10.1016/s0090-4295(01)01424-8. PY - 2001 SN - 0090-4295 SP - 853-8 ST - Influence of environmental factors on chronic prostatitis-like symptoms in young men: results of a community-based survey T2 - Urology TI - Influence of environmental factors on chronic prostatitis-like symptoms in young men: results of a community-based survey VL - 58 ID - 3764 ER - TY - JOUR AB - OBJECTIVES: To study the prevalence of idiopathic musculoskeletal pain (IMSP) in school going children and its impact on daily life. METHODS: One thousand eighteen apparently healthy school children aged 5-16 years were assessed and analysed for IMSP and its associated problems. Standard tests for significance were applied. RESULTS: One hundred and sixty-five (16.2%) children mostly males (55.2%) reported IMSP. Lower limbs (52.1%) were the most common location of pain. More than 1 year of pain history was present in 15%. Thirty-seven percent children complained of discomfort during walking, 30.9%, had pain during physical exercise, 29.2% had difficulty attending lessons and 4.2% had interference in pursuing hobbies. The children were also further sub grouped into preadolescents and adolescents. There was significant difference in pain duration and duration of each pain episode in the two groups (p=0.01). A significant number of children (21.2%) with IMSP reported school absenteeism (p<0.001). A significant number of adolescents had history positive for contact sports (p=0.001). Sleep disturbances were also reported to be higher in children with IMSP (29% vs. 5.7%, p=0.001). Other associated problems in children with IMSP found were day time tiredness (51.1%), headache (47.3%) and abdominal pain (24.8%). CONCLUSIONS: Prevalence of IMSP in school children aged 5-16 yrs was found to be 16.2% and a significant percentage of these children experience interference with daily activities including school absenteeism. AD - Dr. Ram Manohar Lohia Hospital and Post Graduate Institute of Medical Education and Research, Departament of Pediatrics, New Delhi, India. Dr. Ram Manohar Lohia Hospital and Post Graduate Institute of Medical Education and Research, Departament of Pediatrics, New Delhi, India. Electronic address: tribhuvanpal@gmail.com. AN - 28137406 AU - Kumar, G. AU - Chhabra, A. AU - Dewan, V. AU - Yadav, T. P. DA - Jan-Feb DO - 10.1016/j.rbre.2015.07.015 DP - NLM ET - 2017/02/01 IS - 1 KW - Activities of Daily Living/*psychology Adolescent Age of Onset Child Chronic Disease Cross-Sectional Studies Exercise Female Humans India/epidemiology Joint Instability/*epidemiology/*physiopathology/psychology Male Musculoskeletal Pain/*epidemiology/*physiopathology/psychology Pain Measurement Prevalence Dor musculoesquelética idiopática Idiopathic musculoskeletal pain Impact Impacto Prevalência LA - eng por N1 - 2255-5021 Kumar, Ganesh Chhabra, Amieleena Dewan, Vivek Yadav, Tribhuvan Pal Journal Article Brazil Rev Bras Reumatol Engl Ed. 2017 Jan-Feb;57(1):8-14. doi: 10.1016/j.rbre.2015.07.015. Epub 2015 Sep 4. PY - 2017 SN - 2255-5021 SP - 8-14 ST - Idiopathic musculoskeletal pain in Indian children-Prevalence and impact on daily routine T2 - Rev Bras Reumatol Engl Ed TI - Idiopathic musculoskeletal pain in Indian children-Prevalence and impact on daily routine VL - 57 ID - 3626 ER - TY - JOUR AB - AIM To find the association between asthma and different types of functional abdominal pain disorders (FAPDs) among teenagers. METHOD A cross-sectional study was conducted among 13 to 15-year-old children from six randomly selected schools in Anuradhapura district of Sri Lanka. Data were collected using translated and validated self- administered questionnaires (Rome III questionnaire, International Study on Asthma and Allergies in Child-hood questionnaire, and Pediatric Quality of Life Inventory 4.0) and administered under an examination setting after obtaining parental consent and assent. RESULTS Of the 1101 children included in the analysis, 157 (14.3%) had asthma and 101 (9.2%) had at least one FAPDs. Of children with asthma, 19.1% had at least one type of FAPDs. Prevalence rates of functional abdominal pain (FAP) (8.9% vs 3.3% in non-asthmatics), functional dyspepsia (FD) (2.5% vs 0.7%), and abdominal migraine (AM) (3.2% vs 0.4%) were higher in those with asthma (P < 0.05, multiple logistic regression analysis), but not in those with irritable bowel syndrome (4.5% vs 3.1%, P = 0.2). Severe abdominal pain (10.8% vs 4.6%), bloating (16.6% vs 9.6%), nausea (6.4% vs 2.9%), and anorexia (24.2% vs 16.2%) were more prevalent among asthmatics (P < 0.05). Lower gastrointestinal symptoms did not show a significant difference. Scores obtained for health related quality of life (HRQoL) were lower in those with asthma and FAPDs (P < 0.05, unpaired t-test). CONCLUSION Asthma is associated with three different types of FAPDs, namely, FD, AM, and FAR HRQoL is significantly impaired in teenagers with asthma and FAPDs. AN - WOS:000452438600010 AU - Kumari, M. V. AU - Devanarayana, N. M. AU - Amarasiri, L. AU - Rajindrajith, S. DA - Dec DO - 10.12998/wjcc.v6.i15.944 IS - 15 N1 - Kumari, Manori Vijaya Devanarayana, Niranga Manjuri Amarasiri, Lakmali Rajindrajith, Shaman PY - 2018 SN - 2307-8960 SP - 944-951 ST - Association between functional abdominal pain disorders and asthma in adolescents: A cross-sectional study T2 - World Journal of Clinical Cases TI - Association between functional abdominal pain disorders and asthma in adolescents: A cross-sectional study UR - ://WOS:000452438600010 VL - 6 ID - 1975 ER - TY - JOUR AB - OBJECTIVE: The occurrence of orofacial pain and chronic pain are frequent subjects for study today, but few studies have been made on dental pain in Brazil. The objective of the study was to assess the prevalence of dental pain and the associated factors as the reason for visiting a dentist among adults. METHODS: A cross-sectional study was carried out among 860 workers aged 18-58 years at a cooperative located in the State of Santa Catarina, in 1999. The clinical examinations and interviews were carried out by dentists who had received prior guidance. Complaints of dental pain as the reason for the last visit to a dentist were analyzed as the dependent variable, in relation to the socioeconomic and demographic conditions, access to dental services, shift pattern and caries (via the DMFT index), as the independent variables. Non-conditional multiple logistic regression analysis was utilized. RESULTS: The prevalence of dental pain as the reason for the last visit to a dentist was 18.7% (CI 95%: 15.9-20.1) and the mean DMFT index (decayed, missing and filled teeth) was 20.2 (CI 95%: 19.7-20.7), with 54% represented by the 'missing' component. The following were independently associated with the presence of dental pain: schooling of less than or equal to eight years (OR=1.9; CI 95%: 1.1-3.1); four to fifteen teeth lost due to caries (OR=2.6; CI 95%: 1.4-4.9); 16 to 32 teeth lost due to caries (OR=2.5; CI 95%: 1.1-5.8); and not having visited the company's dental service (OR=2.8; CI 95%: 1.6-5.1). CONCLUSIONS: Dental pain reflects the severity of the dental caries, expressed by the 'missing' component of the DMFT and non-usage of the company's dental services. These factors are determined by social conditions and represented by the schooling level. AD - Universidade do Sul de Santa Catarina, Tubarão, SC, Brazil. jtelino@terra.com.br AN - 15243677 AU - Lacerda, J. T. AU - Simionato, E. M. AU - Peres, K. G. AU - Peres, M. A. AU - Traebert, J. AU - Marcenes, W. DA - Jun DO - 10.1590/s0034-89102004000300017 DP - NLM ET - 2004/07/10 IS - 3 KW - Adolescent Adult *Appointments and Schedules Brazil/epidemiology Cross-Sectional Studies DMF Index Dental Caries/*epidemiology Female Humans Male Middle Aged Prevalence Risk Factors Toothache/*epidemiology LA - por N1 - Lacerda, Josimari Telino de Simionato, Eliana Maria Peres, Karen Glazer Peres, Marco Aurélio Traebert, Jefferson Marcenes, Wagner English Abstract Journal Article Brazil Rev Saude Publica. 2004 Jun;38(3):453-8. doi: 10.1590/s0034-89102004000300017. Epub 2004 Jul 8. OP - Dor de origem dental como motivo de consulta odontológica em uma população adulta. PY - 2004 SN - 0034-8910 (Print) 0034-8910 SP - 453-8 ST - [Dental pain as the reason for visiting a dentist in a Brazilian adult population] T2 - Rev Saude Publica TI - [Dental pain as the reason for visiting a dentist in a Brazilian adult population] VL - 38 ID - 4128 ER - TY - JOUR AB - BACKGROUND: OTC analgesics were released for sale outside pharmacies in Norway in 2003. This study assesses indications and frequency of use of these drugs among 15-16 year-old teenagers in Norway after 2003. MATERIAL AND METHOD: We developed a questionnaire, which contained 65 questions with one or more response options. This was given to all pupils in the final grade at six junior high schools in a town with 60,000 inhabitants (Drammen). RESULTS: 367 of 626 (58.6 %) pupils participated. 50 % of the boys and 71 % of the girls had used OTC analgesics during the last four weeks; 26 % of them on a daily or weekly basis. Girls experienced episodes of pain more frequently than boys, but the proportion of episodes treated with analgesics did not differ between the sexes. Headache and muscle pain were common. Half of those with severe headache/migraine used OTC analgesics on a daily or weekly basis. The teenagers reported several reasons for experiencing pain and discomfort, such as long time spent in front of various screens, tight time schedules with physical exercise and friends, drinking too little and much noise in the classroom. INTERPRETATION: Use of OTC analgesics has increased considerably among Norwegian teenagers. Drug-induced headache may occur as an adverse event. If more effort is made to improve life situations that adolescents perceive as painful and a cause of discomfort, the need for OTC analgesics may be reduced. AD - Institutt for allmenn- og samfunnsmedisin, Det medisinske fakultet, Universitetet i Oslo, Postboks 1130, Blindern 0318 Oslo, Norway. per.lagerlov@medisin.uio.no AN - 19690592 AU - Lagerløv, P. AU - Holager, T. AU - Helseth, S. AU - Rosvold, E. O. DA - Aug 13 DO - 10.4045/tidsskr.09.32759 DP - NLM ET - 2009/08/20 IS - 15 KW - Adolescent Analgesics/*administration & dosage/adverse effects Drug Utilization Female Humans Male Nonprescription Drugs/*administration & dosage/adverse effects Norway/epidemiology Pain/*drug therapy/epidemiology Self Medication Sex Factors Surveys and Questionnaires LA - nor N1 - 0807-7096 Lagerløv, Per Holager, Tanja Helseth, Sølvi Rosvold, Elin O English Abstract Journal Article Research Support, Non-U.S. Gov't Norway Tidsskr Nor Laegeforen. 2009 Aug 13;129(15):1447-50. doi: 10.4045/tidsskr.09.32759. OP - Selvmedisinering med reseptfrie smertestillende legemidler hos 15-16-åringer. PY - 2009 SN - 0029-2001 SP - 1447-50 ST - [Self-medication with over-the-counter analgesics among 15-16 year-old teenagers] T2 - Tidsskr Nor Laegeforen TI - [Self-medication with over-the-counter analgesics among 15-16 year-old teenagers] VL - 129 ID - 4015 ER - TY - JOUR AB - Objective The aim of this study was to describe how different adolescents experience and manage pain in their daily life, with a focus on their use of over-the-counter analgesics. More specifically, the aim was to explore different patterns among the adolescents in pain descriptions, in the management of pain, in relationships with others, and in their daily life. Design Qualitative semistructured interviews on experiences with pain, pain management and involvement of family and friends during pain. Pain and stress management strategies and attachment theory will be in focus for interpretations. Participants and setting 25 participants aged 15-16-years from six different junior high schools, both genders, with and without immigrant background were interviewed at their local schools in Norway. Results We identified 4 groups of adolescents with similarities in attitudes and management strategies to pain: pain is manageable', pain is communicable', pain is inevitable' and pain is all over'. The participants within each group differed in how they engaged their parents in pain; how they perceived, communicated and managed pain; and how they involved emotions and used over-the-counter analgesics. Conclusions The adolescents' different involvement with the family during pain related to their pain perception and management. Knowledge of the different ways of approaching pain is important when supporting adolescents and may be a subject for further research on the use of over-the-counter analgesics in the family. AN - WOS:000374052300077 AU - Lagerlov, P. AU - Rosvold, E. O. AU - Holager, T. AU - Helseth, S. C7 - e010184 DO - 10.1136/bmjopen-2015-010184 IS - 3 N1 - Lagerlov, Per Rosvold, Elin Olaug Holager, Tanja Helseth, Solvi Rosvold, Elin Olaug/ABE-4929-2020 PY - 2016 SN - 2044-6055 ST - How adolescents experience and cope with pain in daily life: a qualitative study on ways to cope and the use of over-the-counter analgesics T2 - Bmj Open TI - How adolescents experience and cope with pain in daily life: a qualitative study on ways to cope and the use of over-the-counter analgesics UR - ://WOS:000374052300077 VL - 6 ID - 2193 ER - TY - JOUR AB - BACKGROUND: Migraines, Which Affect About 10% Of School-Age Children In The United States, Can Significantly Impair Quality Of Life. Despite Potential Disability, Many Children Do Not Receive Treatment Or Prophylaxis, Since Medications Specifically Approved For Children Are Significantly Less Than For Adults. There Is Also Controversy Surrounding The Apparent Widespread Practice Of Prescribing Off-Label Medications For Children With Migraines. However, Little Research Has Been Done To Identify Physician-Prescribing Patterns Of Migraine Medication For Children. OBJECTIVE: To Investigate The Prevalence And Pattern Of Off-Label Prescribing For Children With Migraines. METHODS: A Secondary Data Analysis Was Conducted Using The Pooled National Ambulatory Medical Care Survey (Namcs) 2011 And 2012. Patients Aged 17 Years Or Younger With A Migraine Diagnosis Were Included. A Series Of Weighted Descriptive Analyses Were Used To Estimate The Prevalence Of Migraine Drugs Prescribed During Pediatric Office Visits. A Weighted Logistic Regression Was Constructed To Compare The Prescribing Patterns Between Off-Label And Fda-Approved Medications. Analyses Used Sas 9.4 Methodology And Incorporated Sample Weights To Adjust For The Complex Sampling Design Employed By Namcs. RESULTS: Of The 12.9 Million Outpatient Visits With A Migraine Diagnosis That Took Place Between 2010 And 2012, 1.2 Million Were Pediatric Visits. Females Accounted For Nearly Twice The Number Of Migraine Visits Than Males (66% Vs. 34%). Children Aged 12-17 Years Accounted For The Highest Frequency Of Visits (84%), Compared With Those Aged Under 12 Years (16%). 66.7% Of These Pediatric Patients Received At Least 1 Migraine Drug. Of These, Off-Label Medications Were Prescribed 1.5 Times More Than Fda-Approved Medications For Children (60.34% Vs. 39.65%). The Results Of Logistic Regression Showed A Significant Likelihood Of Prescribing Off-Label Medications Based On Physician Specialty, Patient Race, And Reason For Visit. Neurologists (Or = 0.028, P < 0.05) And Pediatricians (Or = 0.095, P < 0.05) Were Less Likely To Prescribe Off-Label Drugs Than General And Family Practitioners. Visits For Preventive Care (Or = 5.8, P < 0.05) And Flare-Ups From Chronic Migraines (Or = 5.0, P < 0.05) Were More Likely To Result In Off-Label Drug Prescriptions Than Visits For New Migraine Incidence. CONCLUSIONS: This Study Provides Significant Real-World Evidence Of The Widespread Practice Of Prescribing Off-Label Drugs To Children With Migraines. Although Medical Literature Shows That Off-Label Prescribing May Not Be Harmful, There Is A Dearth Of Research And Practice Guidelines To Help Practitioners Uphold Safety Standards And Ensure The Prescription Of Age-Appropriate Medications To Children. DISCLOSURES: No outside funding supported this study. The authors report no potential conflicts of interest relevant to this research. Lai and Ting contributed to study concept and design and collected the data, along with the other authors. Data interpretation was performed by Lai, Koh, Obi, Ho, and Ting. The manuscript was written and revised by Lai, Koh, and Ho, with assistance from Ting and Obi. AD - 1 Nova Southeastern University College of Pharmacy, Fort Lauderdale, Florida. 2 University of Florida College of Liberal Arts, Gainesville. AN - 28230456 AU - Lai, L. L. AU - Koh, L. AU - Ho, J. A. AU - Ting, A. AU - Obi, A. DA - Mar DO - 10.18553/jmcp.2017.23.3.382 DP - NLM ET - 2017/02/24 IS - 3 KW - Adolescent Ambulatory Care/methods Child Drug Prescriptions Drug Utilization Female Health Care Surveys/methods Humans Male Migraine Disorders/*drug therapy Off-Label Use Practice Patterns, Physicians' Prescription Drugs/*therapeutic use Prevalence United States LA - eng N1 - 2376-1032 Lai, L Leanne Koh, Leroy Ho, Jane Ai-Chen Ting, Alexander Obi, Augustine Journal Article United States J Manag Care Spec Pharm. 2017 Mar;23(3):382-387. doi: 10.18553/jmcp.2017.23.3.382. PY - 2017 SP - 382-387 ST - Off-Label Prescribing for Children with Migraines in U.S. Ambulatory Care Settings T2 - J Manag Care Spec Pharm TI - Off-Label Prescribing for Children with Migraines in U.S. Ambulatory Care Settings VL - 23 ID - 3595 ER - TY - JOUR AB - Several large, randomized controlled trials have demonstrated the efficacy of topiramate in migraine prophylaxis in adults. However, there are limited data about the use of topiramate in migraine prophylaxis in children. We conducted this single-center, double-blind, placebo-controlled trial to evaluate the efficacy and safety of topiramate in the prophylaxis of migraine in children. A total of 44 children with migraine were randomized using random number tables to receive topiramate (n = 22) or placebo (n = 22). The total duration of treatment was 4 months, including a baseline period of 1 month during which topiramate was titrated weekly in 25-mg increments to 100 mg/d in 2 divided doses or to the maximum tolerated dose. The titration was followed by a 12-week maintenance phase during which topiramate was given in 2 divided doses. The primary outcome measures were the reduction in the mean migraine frequency and severity of headache. Secondary outcome measures included the number of times analgesics were required for a month for acute attacks and functional disability. Functional disability was measured by comparing school absenteeism and Pediatric Migraine Disability Assessment Scale (PedMIDAS). The decrease in mean (+/-SD) monthly migraine frequency from 16.14 (+/-9.35) at baseline to 4.27 (+/-1.95) at the end of the study in the topiramate group was significantly greater as compared with a decrease from 13.38 (+/-7.78) to 7.48 (+/-5.94) at the end of the study in the placebo group (P = .025). The difference in number of rescue medications used for topiramate and placebo was not statistically significant (P = .059). There was a statistically significant decrease in the PedMIDAS score from 50.66 (+/-32.1) to 10.42 (+/-6.39) at the end of the study in the topiramate group compared with a decrease from 42.66 (+/-27.5) to 23.7 (+/-19.1) at the end of 4 months in the placebo group (P = .003). The decrease in school absenteeism was significant with topiramate compared with placebo (P = .002). Weight loss, decreased concentration in school, sedation, and parasthesias were important side effects with topiramate. Most of these side effects were mild to moderate and were not significant enough to cause dropout from the study. AD - Department of Pediatrics, Advanced Pediatric Center, Postgraduate Institute of Medical Education and Research, Chandigarh, India. AN - 17715274 AU - Lakshmi, C. V. AU - Singhi, P. AU - Malhi, P. AU - Ray, M. DA - Jul DO - 10.1177/0883073807304201 DP - NLM ET - 2007/08/24 IS - 7 KW - Adolescent Analysis of Variance Anticonvulsants/therapeutic use Child Dose-Response Relationship, Drug Double-Blind Method Drug Administration Schedule Female Fructose/*analogs & derivatives/therapeutic use Humans Male Migraine Disorders/*prevention & control/psychology Neurotransmitter Agents/*therapeutic use Quality of Life/psychology Topiramate LA - eng N1 - Lakshmi, C V S Singhi, Pratibha Malhi, Prahbhjot Ray, Munni Journal Article Randomized Controlled Trial United States J Child Neurol. 2007 Jul;22(7):829-35. doi: 10.1177/0883073807304201. PY - 2007 SN - 0883-0738 (Print) 0883-0738 SP - 829-35 ST - Topiramate in the prophylaxis of pediatric migraine: a double-blind placebo-controlled trial T2 - J Child Neurol TI - Topiramate in the prophylaxis of pediatric migraine: a double-blind placebo-controlled trial VL - 22 ID - 3543 ER - TY - JOUR AB - Background: Pain-related functional gastrointestinal disorders (P-FGIDs; eg, irritable bowel syndrome) are highly prevalent in children and associated with low quality of life, anxiety, and school absence. Treatment options are scarce, and there is a need for effective and accessible treatments. Internet-delivered cognitive behavior therapy (Internet-CBT) based on exposure exercises is effective for adult and adolescent irritable bowel syndrome, but it has not been evaluated for younger children. Objective: The objective of this study was to assess acceptability, feasibility, and potential clinical efficacy of Internet-CBT for children with P-FGIDs. Methods: This was a feasibility study with a within-group design. We included 31 children aged 8-12 years and diagnosed with P-FGID, according to the ROME III criteria. Mean duration of abdominal symptoms at baseline was 3.8 years (standard deviation [SD] 2.6). The treatment was therapist-guided and consisted of 10 weekly modules of exposure-based Internet-CBT. The children were instructed to provoke abdominal symptoms in a graded manner and to engage in previously avoided activities. The parents were taught to decrease their attention to their children's pain behaviors and to reinforce and support their work with the exposures. Assessments included treatment satisfaction, subjective treatment effect, gastrointestinal symptoms, quality of life, pain intensity, anxiety, depression, and school absence. Data were collected at pretreatment, posttreatment, and 6-month follow-up. Means, standard errors (SEs), and Cohen d effect sizes were estimated based on multi-level linear mixed models. Results: Most children 25/31 (81%) completed 9 or 10 of the 10 treatment modules. Almost all children, 28/31 (90%), reported that the treatment had helped them to deal more effectively with their symptoms, and 27/31 (87%) children declared that their symptoms had improved during the treatment. Assessments from the parents were in accordance with the children's reports. No child or parent reported that the symptoms had worsened. We observed a large within-group effect size on the primary outcome measure, child-rated gastrointestinal symptoms from pretreatment to posttreatment (Cohen d=1.14, P<.001, 95% CI 0.69-1.61), and this effect size was maintained at 6-month follow-up (Cohen d=1.40, P<.001, 95% CI 1.04-1.81). We also observed significant improvements from pretreatment to posttreatment on a wide range of child-and parent-rated measures including quality of life, pain intensity, anxiety, depression, and school absence. All results remained stable or were further improved at 6-month follow-up. Conclusions: This study shows that children with longstanding P-FGIDs, and their parents, perceive exposure-based Internet-CBT as a helpful and feasible treatment. The included children improved significantly despite a long duration of abdominal symptoms before the intervention. The treatment shows potential to be highly effective for P-FGIDs. The results need to be confirmed in a randomized controlled trial (RCT). AN - WOS:000414982500003 AU - Lalouni, M. AU - Ljotsson, B. AU - Bonnert, M. AU - Hedman-Lagerlof, E. AU - Hogstrom, J. AU - Serlachius, E. AU - Olen, O. C7 - e32 DA - Jul-Sep DO - 10.2196/mental.7985 IS - 3 N1 - Lalouni, Maria Ljotsson, Brjann Bonnert, Marianne Hedman-Lagerlof, Erik Hogstrom, Jens Serlachius, Eva Olen, Ola Serlachius, Eva/E-8956-2013; Bonnert, Marianne/M-8358-2019 Serlachius, Eva/0000-0001-7115-6422; Bonnert, Marianne/0000-0002-0140-773X; Ljotsson, Brjann/0000-0001-8086-1668; Olen, Ola/0000-0002-5478-7019; Hogstrom, Jens/0000-0002-5313-8498; Lalouni, Maria/0000-0002-6818-8156 PY - 2017 SN - 2368-7959 ST - Internet-Delivered Cognitive Behavioral Therapy for Children With Pain-Related Functional Gastrointestinal Disorders: Feasibility Study T2 - Jmir Mental Health TI - Internet-Delivered Cognitive Behavioral Therapy for Children With Pain-Related Functional Gastrointestinal Disorders: Feasibility Study UR - ://WOS:000414982500003 VL - 4 ID - 2089 ER - TY - JOUR AB - BACKGROUND & AIMS: Scalable and effective treatments are needed for children with functional abdominal pain disorders (FAPDs). We performed a randomized controlled trial of the efficacy and cost effectiveness of cognitive behavioral therapy delivered online (Internet-CBT) compared with usual therapy. METHODS: We studied children (age, 8-12 y) diagnosed with FAPDs, based on the Rome IV criteria, in Sweden from September 2016 through April 2017. The patients were assigned randomly to groups that received 10 weeks of therapist-guided, internet-delivered cognitive behavioral therapy (Internet-CBT, n = 46) or treatment as usual (treatments within the health care and school systems, including medications and visits to doctors and other health care professionals; n = 44). The primary outcome was global child-rated gastrointestinal symptom severity assessed using the Pediatric Quality of Life Gastrointestinal Symptom scale. All outcomes were collected from September 2016 through January 2018. Secondary outcomes included quality of life, gastrointestinal-specific anxiety, avoidance behaviors, and parental responses to children's symptoms. Societal costs and costs for health care consumption were collected during the treatment. RESULTS: Children who received Internet-CBT had a significantly larger improvement in gastrointestinal symptom severity with a medium effect size (Cohen's d = 0.46; 95% CI, 0.05-0.88; number needed to treat, 3.8) compared with children who received the treatment as usual. The children's quality of life, gastrointestinal-specific anxiety, avoidance behaviors, and parental responses to children's symptoms also improved significantly in the Internet-CBT group compared with the treatment as usual group. The effects of Internet-CBT persisted through 36 weeks of follow-up evaluation. Children who received Internet-CBT had significantly less health care use than children who received treatment as usual, with an average cost difference of US $137 (P = .011). We calculated a cost savings of US $1050 for every child treated with Internet-CBT compared with treatment as usual. CONCLUSIONS: In a randomized trial of pediatric patients with FAPDs, we found Internet-CBT to be clinically cost effective compared with treatment as usual. Internet-CBT has the potential to increase the availability of treatment for a number of patients and reduce health care costs. ClinicalTrials.gov: NCT02873078. AD - Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden; Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden. Electronic address: maria.lalouni@ki.se. Division of Psychology, Karolinska Institutet, Stockholm, Sweden; Center for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden. Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden; Division of Psychology, Karolinska Institutet, Stockholm, Sweden; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden. Department of Paediatric Gastroenterology and Nutrition, Emma Children's Hospital/Academic Medical Center, Amsterdam, The Netherlands. Center for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden. Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden; Center for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden. Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Center for Functional Gastrointestinal and Motility Disorders, University of North Carolina, Chapel Hill, North Carolina. Division of Psychology, Karolinska Institutet, Stockholm, Sweden; Osher Center for Integrative Medicine, Karolinska Institutet, Stockholm, Sweden. Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden; Department of Pediatric Gastroenterology and Nutrition, Sachs' Children's Hospital, Stockholm, Sweden. AN - 30502501 AU - Lalouni, M. AU - Ljótsson, B. AU - Bonnert, M. AU - Ssegonja, R. AU - Benninga, M. AU - Bjureberg, J. AU - Högström, J. AU - Sahlin, H. AU - Simrén, M. AU - Feldman, I. AU - Hedman-Lagerlöf, E. AU - Serlachius, E. AU - Olén, O. DA - Oct DO - 10.1016/j.cgh.2018.11.043 DP - NLM ET - 2018/12/07 IS - 11 KW - Abdominal Pain/*therapy Child Cognitive Behavioral Therapy/economics/*methods Cost-Benefit Analysis Female *Health Care Costs Humans *Internet Irritable Bowel Syndrome/*therapy Male Quality of Life Sweden Telemedicine/economics/*methods *Dyspepsia *ibs *Irritable Bowel Syndrome *Remote Access to Therapy LA - eng N1 - 1542-7714 Lalouni, Maria Ljótsson, Brjánn Bonnert, Marianne Ssegonja, Richard Benninga, Marc Bjureberg, Johan Högström, Jens Sahlin, Hanna Simrén, Magnus Feldman, Inna Hedman-Lagerlöf, Erik Serlachius, Eva Olén, Ola Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't United States Clin Gastroenterol Hepatol. 2019 Oct;17(11):2236-2244.e11. doi: 10.1016/j.cgh.2018.11.043. Epub 2018 Nov 28. PY - 2019 SN - 1542-3565 SP - 2236-2244.e11 ST - Clinical and Cost Effectiveness of Online Cognitive Behavioral Therapy in Children With Functional Abdominal Pain Disorders T2 - Clin Gastroenterol Hepatol TI - Clinical and Cost Effectiveness of Online Cognitive Behavioral Therapy in Children With Functional Abdominal Pain Disorders VL - 17 ID - 3942 ER - TY - JOUR AB - Background Children with pain-related functional gastrointestinal disorders (P-FGIDs) have an increased risk for school absenteeism, depression, anxiety and low quality of life. Exposure-based cognitive behavior therapy (CBT) has shown large treatment effects in adults with irritable bowel syndrome, but has not been tested for children 8-12 years with PFGIDs. Aim The aim of this trial was to test the feasibility, acceptability and potential efficacy of a newly developed exposure-based CBT for children with P-FGIDs. Method The children (n = 20) with a P-FGID, were referred by their treating physicians. The participants received 10 weekly sessions of exposure-based CBT and were assessed at pretreatment, post-treatment and 6-month follow-up. Results Children improved significantly on the primary outcome measure pain intensity at post (Cohen's d = 0.40, p = 0.049) and at 6-month follow-up (Cohen's d = 0.85, p = 0.004). Improvements were also seen in pain frequency, gastrointestinal symptoms, quality of life, depression, anxiety, school absenteeism and somatic symptoms. Improvements were maintained or further increased at 6-month follow-up. The children engaged in the exposures and were satisfied with the treatment. Conclusions Exposure-based CBT for children with P-FGIDs is feasible, acceptable and potentially efficacious. AN - WOS:000385505800104 AU - Lalouni, M. AU - Olen, O. AU - Bonnert, M. AU - Hedman, E. AU - Serlachius, E. AU - Ljotsson, B. C7 - e0164647 DA - Oct DO - 10.1371/journal.pone.0164647 IS - 10 N1 - Lalouni, Maria Olen, Ola Bonnert, Marianne Hedman, Erik Serlachius, Eva Ljotsson, Brjann Serlachius, Eva/E-8956-2013; Bonnert, Marianne/P-3021-2017; Bonnert, Marianne/M-8358-2019 Serlachius, Eva/0000-0001-7115-6422; Bonnert, Marianne/0000-0002-0140-773X; Hedman-Lagerlof, Erik/0000-0002-7939-9848; Olen, Ola/0000-0002-5478-7019; Lalouni, Maria/0000-0002-6818-8156 PY - 2016 SN - 1932-6203 ST - Exposure-Based Cognitive Behavior Therapy for Children with Abdominal Pain: A Pilot Trial T2 - Plos One TI - Exposure-Based Cognitive Behavior Therapy for Children with Abdominal Pain: A Pilot Trial UR - ://WOS:000385505800104 VL - 11 ID - 2141 ER - TY - JOUR AB - Cost-effectiveness and cost per successful treatment has been evaluated in 186 outpatients randomised to treat moderate to severe migraine attacks either with subcutaneous sumatriptan 6 mg (n = 97) or with their current therapy (n = 89) during an open, multicentre study of 3 months. Within 2 hours, headache severity decreased to none/mild in 86% of all attacks in the sumatriptan group (STG) compared to 25% in the customary group (CTG). Migraine was alleviated earlier in the STG than in the CTG (median 3.78 vs. 13.39 hours, p < 0.0001). The direct and total cost of treatment was 133 and 2012 BF, respectively, in the CTG and 1400 and 2522 BF, respectively, in the STG. Measuring the effectiveness of earlier pain relief with sumatriptan, the incremental cost-effective ratios for direct and total cost were 132 and 53 BF per hour of relieved pain, respectively. For this price, significantly more sumatriptan patients improved their quality of life by more than 20% (61.6 vs. 20.6% patients, p < 0.001) and less sumatriptan patient consulted a medical professional (11.3 vs. 29.2% patients, p < 0.01), used less medication for adverse events (6.2 vs. 22.5%, p < 0.001) and suffered less from associated migraine symptoms. The median number of hours of diminished work-efficiency (3 vs. 7 hours, p < 0.01) or of suspension of non-professional activity (10 vs. 24 hours, p < 0.001) was also significantly lower in the STG. The total cost per successfully treated patient was lower in the STG. Sumatriptan is more effective, provides a better quality of life, reduces health care resource utilisation, and improves work productivity as compared to the CTG, thereby resulting in a favourable cost-effectiveness ratio. AD - Department of Neurology, Mont-Godinne University Hospital, Louvain Medical School, Yvoir, Belgium. AN - 9922821 AU - Laloux, P. AU - Vakaet, A. AU - Monseu, G. AU - Jacquy, J. AU - Bourgeois, P. AU - van der Linden, C. DA - Dec DP - NLM ET - 1999/01/29 IS - 4 KW - Absenteeism Adolescent Adult Analgesics/administration & dosage/adverse effects/economics/therapeutic use Cost-Benefit Analysis Drug Costs Female Humans Injections, Subcutaneous Male Middle Aged Migraine Disorders/*drug therapy/economics Patient Acceptance of Health Care Quality of Life Safety Serotonin Receptor Agonists/administration & dosage/adverse effects/economics/*therapeutic use Sumatriptan/administration & dosage/adverse effects/economics/*therapeutic use Vasoconstrictor Agents/administration & dosage/adverse effects/economics/*therapeutic use LA - eng N1 - Laloux, P Vakaet, A Monseu, G Jacquy, J Bourgeois, P van der Linden, C Clinical Trial Comparative Study Journal Article Multicenter Study Randomized Controlled Trial Research Support, Non-U.S. Gov't Italy Acta Neurol Belg. 1998 Dec;98(4):332-41. PY - 1998 SN - 0300-9009 (Print) 0300-9009 SP - 332-41 ST - Subcutaneous sumatriptan compared with usual acute treatments for migraine: clinical and pharmacoeconomic evaluation T2 - Acta Neurol Belg TI - Subcutaneous sumatriptan compared with usual acute treatments for migraine: clinical and pharmacoeconomic evaluation VL - 98 ID - 3749 ER - TY - JOUR AB - OBJECTIVE: To evaluate the cost effectiveness, cost utility, and cost-benefit of an integrated care programme compared with usual care for sick listed patients with chronic low back pain. DESIGN: Economic evaluation alongside a randomised controlled trial with 12 months' follow-up. SETTING: Primary care (10 physiotherapy practices, one occupational health service, one occupational therapy practice) and secondary care (five hospitals) in the Netherlands, 2005-9. PARTICIPANTS: 134 adults aged 18-65 sick listed because of chronic low back pain: 66 were randomised to integrated care and 68 to usual care. INTERVENTIONS: Integrated care consisted of a workplace intervention based on participatory ergonomics, with involvement of a supervisor, and a graded activity programme based on cognitive behavioural principles. Usual care was provided by general practitioners and occupational physicians according to Dutch guidelines. MAIN OUTCOME MEASURES: The primary outcome was duration until sustainable return to work. The secondary outcome was quality adjusted life years (QALYs), measured using EuroQol. RESULTS: Total costs in the integrated care group (£13 165, SD £13 600) were significantly lower than in the usual care group (£18 475, SD £13 616). Cost effectiveness planes and acceptability curves showed that integrated care was cost effective compared with usual care for return to work and QALYs gained. The cost-benefit analyses showed that every £1 invested in integrated care would return an estimated £26. The net societal benefit of integrated care compared with usual care was £5744. CONCLUSIONS: Implementation of an integrated care programme for patients sick listed with chronic low back pain has a large potential to significantly reduce societal costs, increase effectiveness of care, improve quality of life, and improve function on a broad scale. Integrated care therefore has large gains for patients and society as well as for employers. AD - Department of Public and Occupational Health, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, Netherlands. AN - 21118874 AU - Lambeek, L. C. AU - Bosmans, J. E. AU - Van Royen, B. J. AU - Van Tulder, M. W. AU - Van Mechelen, W. AU - Anema, J. R. C2 - PMC2995018 at www.icmje.org/coi_disclosure.pdf (available on request from the corresponding author) and declare: no support from any company for the submitted work; no financial relationships with any companies that might have an interest in the submitted work in the previous 3 years; no other relationships or activities that could appear to have influenced the submitted work. DA - Nov 30 DO - 10.1136/bmj.c6414 DP - NLM ET - 2010/12/02 KW - Absenteeism Adolescent Adult Aged Chronic Disease Cost-Benefit Analysis Delivery of Health Care, Integrated Health Resources/statistics & numerical data Humans Low Back Pain/economics/*rehabilitation Middle Aged Netherlands Occupational Therapy Physical Therapy Modalities Quality-Adjusted Life Years Rehabilitation, Vocational/economics Sick Leave Young Adult LA - eng N1 - 1756-1833 Lambeek, Ludeke C Bosmans, Judith E Van Royen, Barend J Van Tulder, Maurits W Van Mechelen, Willem Anema, Johannes R Journal Article Multicenter Study Randomized Controlled Trial Research Support, Non-U.S. Gov't BMJ. 2010 Nov 30;341:c6414. doi: 10.1136/bmj.c6414. PY - 2010 SN - 0959-8138 (Print) 0959-8138 SP - c6414 ST - Effect of integrated care for sick listed patients with chronic low back pain: economic evaluation alongside a randomised controlled trial T2 - Bmj TI - Effect of integrated care for sick listed patients with chronic low back pain: economic evaluation alongside a randomised controlled trial VL - 341 ID - 3426 ER - TY - JOUR AB - OBJECTIVE: Examine the impact of migraine on work productivity, and particularly the association between time of migraine onset and lost productivity as measured by absenteeism and presenteeism. METHODS: A total of 509 people with migraine completed one online baseline survey and a diary survey after each of their next three migraines. All subjects were 18 or older and employed full time. RESULTS: Sixty-four percent of migraines occurred on a workday. Of these, 68% resulted in some work productivity impact in the form of absenteeism or presenteeism. Migraines occurring during usual sleeping hours or prior to the start of work had the greatest impact on productivity. CONCLUSIONS: Findings indicate that absenteeism and presenteeism are both substantial contributors to work productivity loss. Primary factors associated with lost productivity include pain severity, migraine symptoms, and sleep disturbance. AD - Wesley Neurology Clinic, Memphis, Tennessee, USA. AN - 21187794 AU - Landy, S. H. AU - Runken, M. C. AU - Bell, C. F. AU - Higbie, R. L. AU - Haskins, L. S. DA - Jan DO - 10.1097/JOM.0b013e31812006365 DP - NLM ET - 2010/12/29 IS - 1 KW - *Absenteeism Adolescent Adult *Efficiency Female Health Surveys Humans Male Middle Aged Migraine Disorders/*economics Prospective Studies Severity of Illness Index Sleep Wake Disorders/economics LA - eng N1 - 1536-5948 Landy, Stephen H Runken, M Chris Bell, Christopher F Higbie, Rachel L Haskins, Lisa S Journal Article United States J Occup Environ Med. 2011 Jan;53(1):74-81. doi: 10.1097/JOM.0b013e31812006365. PY - 2011 SN - 1076-2752 SP - 74-81 ST - Assessing the impact of migraine onset on work productivity T2 - J Occup Environ Med TI - Assessing the impact of migraine onset on work productivity VL - 53 ID - 3261 ER - TY - JOUR AB - Pain arising from the chest area creates anxiety in children and their parents, often leading to unnecessary activity restriction, school absences, and medical utilization. A thorough but pragmatic evaluation requires a grasp of the pathophysiology of several organ systems and an understanding of epidemiologic and behavioral patterns specific to children. Few symptoms in pediatrics test a clinician's skill more than chest pain. Though the etiology is frequently benign, it is often uncertain, and sprinkled among cases of chest pain are potentially fatal conditions. This review summarizes chest pain in children of all ages, with particular emphasis on adolescents. We review the organic causes including musculoskeletal trauma, strain and inflammation, respiratory conditions such as occult asthma, pneumonia and bronchitis, and the important role of esophageal disease. We discuss the relatively minor role of cardiac disease, but highlight the conditions that are vital to consider, such as arrhythmia, mitral valve disease, Kawasaki syndrome, Marfan syndrome, and cocaine use. Anxiety, depression, and other psychological factors often further complicate the presentation. A pediatrician's best tools are diagnostic acumen, which may be lifesaving, and supportive dialogue, to impart reassurance to a worried family. We explore the most common and most lethal causes by age, organ system, and predisposing illness. We review the neuroanatomic considerations important in visceral, chest wall, and mediastinal pain, and the sensation within the lung, airways, and pleurae. Lastly, we highlight pragmatic 'take-home' tips for the clinician, most of which involve good history-taking and physical examination, but also include the utility of basic testing that can detect the rare cases of fatal cardiopulmonary disease. AN - WOS:000433870900006 AU - Lang, J. E. AU - Colin, A. A. DO - 10.2174/157339606778019710 IS - 3 N1 - Lang, Jason E. Colin, Andrew A. 1875-6336 PY - 2006 SN - 1573-3963 SP - 245-258 ST - Chest Pain in Children T2 - Current Pediatric Reviews TI - Chest Pain in Children UR - ://WOS:000433870900006 VL - 2 ID - 2747 ER - TY - JOUR AB - Children and adolescents with inflammatory rheumatic diseases should practice sports to benefit physically and mentally. For this purpose, inflammatory activity in affected joints should be minimal. The selection of an individually suitable sport should be based on medical examination and consultation. The chosen sport must be adapted to the status of the illness, should be enjoyable but not performance oriented and without competitive character. Inflamed joints can be damaged by mechanical overloading during physical activity. Therefore, joint protection is highly important. Pain is usually the best indicator of the load limit and should guide the intensity of training. Current data show that moderate exercise improves physical function and relieves pain. Obesity, which causes strain on inflamed joints, can be reduced. Furthermore, stabilization of the cardiac function and circulatory system can be achieved. The article presents an overview of the topic juvenile arthritis and sports/exercise. AN - WOS:000307553800010 AU - Lange, U. AU - Muller-Ladner, U. AU - Mulich, C. DA - Aug DO - 10.1007/s00112-012-2642-4 IS - 8 N1 - Lange, U. Mueller-Ladner, U. Muelich, C. 1433-0474 PY - 2012 SN - 0026-9298 SP - 764-768 ST - Sports and exercise in juvenile idiopathic arthritis T2 - Monatsschrift Kinderheilkunde TI - Sports and exercise in juvenile idiopathic arthritis UR - ://WOS:000307553800010 VL - 160 ID - 2421 ER - TY - JOUR AB - This study investigated whether catastrophic thinking about pain by children with functional abdominal pain or by their parents is associated with health outcomes in the child. Participants were 132 parent-child dyads. Child catastrophizing predicted child depression, anxiety, and functional disability. Parents' catastrophizing cognitions about their own pain predicted self-reported protective responses to their children's abdominal pain (responding in ways that encourage illness behavior). Protectiveness, in turn, predicted child functional disability. All findings held despite controlling for child age, gender, and symptom severity. These results suggest that catastrophic cognitions play an important role in how children and parents cope and respond to functional abdominal pain, and may have implications for assessment and treatment in the clinical setting. AN - WOS:000269318200001 AU - Langer, S. L. AU - Romano, J. M. AU - Levy, R. L. AU - Walker, L. S. AU - Whitehead, W. E. DO - 10.1080/02739610903038750 IS - 3 N1 - Langer, Shelby L. Romano, Joan M. Levy, Rona L. Walker, Lynn S. Whitehead, William E. PY - 2009 SN - 0273-9615 SP - 169-184 ST - Catastrophizing and Parental Response to Child Symptom Complaints T2 - Childrens Health Care TI - Catastrophizing and Parental Response to Child Symptom Complaints UR - ://WOS:000269318200001 VL - 38 ID - 2622 ER - TY - JOUR AB - This study sought to model and test the role of parental catastrophizing in relationship to parent-reported child pain behavior and parental protective (solicitous) responses to child pain in a sample of children with Inflammatory Bowel Disease and their parents (n = 184 dyads). Parents completed measures designed to assess cognitions about and responses to their child's abdominal pain. They also rated their child's pain behavior. Mediation analyses were performed using regression-based techniques and bootstrapping. Results supported a model treating parent-reported child pain behavior as the predictor, parental catastrophizing as the mediator, and parental protective responses as the outcome. Parent-reported child pain behavior predicted parental protective responses and this association was mediated by parental catastrophizing about child pain: indirect effect (SE) = 2.08 (0.56); 95% CI = 1.09, 3.30. The proportion of the total effect mediated was 68%. Findings suggest that interventions designed to modify maladaptive parental responses to children's pain behaviors should assess, as well as target, parental catastrophizing cognitions about their child's pain. AN - WOS:000215764400023 AU - Langer, S. L. AU - Romano, J. M. AU - Mancl, L. AU - Levy, R. L. C7 - 751097 DO - 10.1155/2014/751097 N1 - Langer, Shelby L. Romano, Joan M. Mancl, Lloyd Levy, Rona L. Mancl, Lloyd/0000-0001-8566-8883 2090-1550 PY - 2014 SN - 2090-1542 ST - Parental Catastrophizing Partially Mediates the Association between Parent-Reported Child Pain Behavior and Parental Protective Responses T2 - Pain Research and Treatment TI - Parental Catastrophizing Partially Mediates the Association between Parent-Reported Child Pain Behavior and Parental Protective Responses UR - ://WOS:000215764400023 VL - 2014 ID - 2332 ER - TY - JOUR AB - BACKGROUND: Despite disproportionate rates of cancer morbidity and mortality among African American men, few community-based efforts have been developed and sustained to educate African American men about cancer. The University of Michigan Comprehensive Cancer Center implemented a series of breakfasts to improve cancer awareness, screening, and education among African American men. This article describes the rationale for and history of the community intervention. COMMUNITY CONTEXT: The 21 breakfasts were held from 2008 through mid-2014 in Ypsilanti and Ann Arbor, Michigan. Ypsilanti ranks below Michigan and the nation on most socioeconomic indicators, although most residents are high school graduates (88% in Ypsilanti and 96.5% in Ann Arbor). African American men in Ypsilanti have higher death rates for diseases associated with poor diet and inadequate physical activity compared with Ypsilanti whites and general populations in Michigan and the nation. METHODS: We conducted a multicomponent qualitative process evaluation including staff meetings, conversations with participants, and focus groups. We collected 425 post-event surveys to evaluate the breakfasts quantitatively. OUTCOMES: Participants were African American (85%), were aged 51 to 70 years (54%), had health insurance (89%), and had some college education (38%). Fifty-three percent of participants reported interest in the breakfast topics including nutrition; 46%, prostate cancer; 34%, colorectal cancer, and 32%, pain management; 62% reported willingness to participate in a clinical trial. INTERPRETATION: African American men are interested in learning about health and are willing to attend a health-focused breakfast series. The Men's Fellowship Breakfast is a promising strategy for bringing men together to discuss cancer screening and risk reduction. AD - Postdoctoral Fellow, University of Michigan, Center for Bioethics and Social Sciences in Medicine, 2800 Plymouth Rd, Building 16, Room 400S-15, Ann Arbor, MI 48109. Telephone: 734-615-7974. E-mail: alangfor@umich.edu. Vanderbilt University Institute for Research on Men's Health, Nashville, Tennessee. Centers for Disease Control and Prevention, Atlanta, Georgia. University of Michigan, Ann Arbor, Michigan. AN - 25254982 AU - Langford, A. T. AU - Griffith, D. M. AU - Beasley, D. D. AU - Braxton, E. I. C2 - PMC4176474 DA - Sep 25 DO - 10.5888/pcd11.140187 DP - NLM ET - 2014/09/26 KW - *African Americans Breakfast Cancer Care Facilities/*organization & administration Health Education/organization & administration Health Knowledge, Attitudes, Practice Humans Male Neoplasms/*prevention & control Patient Acceptance of Health Care LA - eng N1 - 1545-1151 Langford, Aisha T Griffith, Derek M Beasley, Derrick D Braxton, Effat Id-Deen Journal Article Research Support, Non-U.S. Gov't Prev Chronic Dis. 2014 Sep 25;11:E164. doi: 10.5888/pcd11.140187. PY - 2014 SN - 1545-1151 SP - E164 ST - A cancer center's approach to engaging African American men about cancer: the men's fellowship breakfast, Southeastern Michigan, 2008-2014 T2 - Prev Chronic Dis TI - A cancer center's approach to engaging African American men about cancer: the men's fellowship breakfast, Southeastern Michigan, 2008-2014 VL - 11 ID - 4225 ER - TY - JOUR AB - OBJECTIVES: The aims of this paper are to report on the prevalence, correlates and treatment of pain in the adult Spanish population. The analysis also explores the association between the experience of pain and health-related quality of life (HRQoL), employment and productivity, and healthcare resource utilization. METHODS: Data are from the Internet-based, 2010 National Health and Wellness Survey (NHWS) Spain. The sample was weighted by age and sex to correspond to the 2010 adult Spanish population. All respondents to the NHWS reported on socio-demographic and economic characteristics, medication adherence and major health conditions. They also reported on their HRQoL (the SF-12), their employment status and workplace productivity experience (WPAI instrument) and their healthcare resource utilization. Persons reporting experiencing pain gave details on conditions causing pain, prescription and over the counter (OTC) medication utilization, duration of utilization and satisfaction with medications. A supplementary analysis evaluated the population prevalence of pain for the five most populous Spanish autonomous communities (regions). RESULTS: An estimated 6.10 million (17.25%) of the adult population of Spain reported experiencing pain in the last month. Of these 11.69% experienced severe pain, 64.17% moderate pain and 24.14% mild pain. Daily pain was experienced by 6.95% of the population The major conditions causing pain are back pain (60.53%) followed by joint pain (40.21%). Sleep difficulties (42.24%) and anxiety (40.62%) were most commonly cited as comorbidities. Prescription medication utilization was most important in the severe and moderate pain categories, with 71.62% reporting they were satisfied with their prescription pain medications. Adherence to pain medications was high with an overall Morisky score of 0.99 (range 0-4). Pain had a major negative effect on labor force participation for those reporting moderate and severe pain with a participation rate of only 42.62% for those with severe pain. Pain was associated with substantial health-related quality of life deficits as measured by the physical and mental score components of the SF-12. In the case of SF-6D utilities, the utility score for the pain population was markedly below that for the no-pain population (0.65 vs. 0.75; p < 0.05).The experience of pain also negatively impacted rates of absenteeism and presenteeism, as well as being associated with greater healthcare resource utilization. Finally, for the five most populous autonomous communities of Spain estimated pain prevalence ranged from 14.80% for Madrid to 18.79% for Comunidad Valenciana. The are a number of limitations which should be noted. First, this is an internet-based sample study and the respondent population may not be representative of the Spanish adult population. Second, respondents are asked to report their experience of pain with no independent clinical conformation. Finally, while a number of obvious acute pain categories are excluded, there is no attempt to arbitrarily define a chronic pain population or to identify pain categories such as neuropathic pain. CONCLUSIONS: The experience of pain represents a substantial burden on both individuals and the Spanish economy. The experience of pain is associated with a substantial reduction in both the PCS component of the SF-12 and SF-6D absolute utilities--most notably in respect of severe pain. The experience of pain is also associated, not only with reduced labor force participation and increased absenteeism and presenteeism, but with substantially higher patterns of healthcare resource utilization. AD - College of Pharmacy, University of Minnesota, 308 Harvard Street SE, Minneapolis, MN 55455, USA. P8366@MSN.com AN - 21574899 AU - Langley, P. C. AU - Ruiz-Iban, M. A. AU - Molina, J. T. AU - De Andres, J. AU - Castellón, J. R. DO - 10.3111/13696998.2011.583303 DP - NLM ET - 2011/05/18 IS - 3 KW - Absenteeism Adolescent Adult Employment Female Health Care Surveys Health Services/statistics & numerical data Humans Male Middle Aged Pain/*drug therapy/*epidemiology Quality of Life Severity of Illness Index Spain/epidemiology Young Adult LA - eng N1 - 1941-837x Langley, Paul C Ruiz-Iban, Miguel Angel Molina, Jesús Tornero De Andres, Jose Castellón, José Ramón González-Escalada Journal Article Research Support, Non-U.S. Gov't England J Med Econ. 2011;14(3):367-80. doi: 10.3111/13696998.2011.583303. Epub 2011 May 17. PY - 2011 SN - 1369-6998 SP - 367-80 ST - The prevalence, correlates and treatment of pain in Spain T2 - J Med Econ TI - The prevalence, correlates and treatment of pain in Spain VL - 14 ID - 3696 ER - TY - JOUR AB - OBJECTIVES: The aims of this paper are to generate estimates of the association between the severity and frequency of pain in Spain and (i) labor force participation and workforce status and (ii) patterns of absenteeism and presenteeism for the employed workforce. METHODS: Data are from the internet-based 2010 National Health and Wellness Survey (NHWS). This survey covers both those who report experiencing pain in the last month as well as the no-pain population. An estimated 17.25% of adults in Spain report experiencing pain in the past month. A series of regression models are developed with the no-pain group as the reference category. The impact of pain, categorized by severity and frequency, is assessed within a labor supply framework for (i) labor force participation and (ii) absenteeism and presenteeism. Both binomial and multinomial logistic models are estimated. RESULTS: The results demonstrate that severe and moderate pain has a significant, substantive, and negative association with labor force participation and, together with the experience of mild pain, a substantive impact on absenteeism and presenteeism within the employed workforce. Compared to no-pain controls, the strongest association is seen in the case of severe pain, notably severe daily pain and labor force participation (odds ratio 0.363; 95% CI: 0.206-0.637). The association of severe pain with labor force participation is also significant (odds ratio 0.356; 95% CI: 0.217-0.585). There is a clear gradient in the association of pain severity and frequency with labor force participation. The impact of pain is far greater than the potential impact of other health status measures (e.g., chronic comorbidities and BMI). Labor force participation is also adversely associated with pain experience. Persons reporting severe daily pain are far more likely not to be in the labor force (relative probabilities 0.339 vs 0.611). The experience of pain, notably severe and frequent pain, also outstrips the impact of other health status factors in absenteeism and presenteeism. In the former case, the odds ratio associated with severe daily pain is 16.216 (95% CI: 5.127-51.283), which contrasts to the odds ratio for the Charlson comorbidity index of 1.460 (95%CI: 1.279-1.666). Similar results hold for presenteeism. The contribution of moderate and mild pain to absenteeism and presenteeism is more marked than for labor force participation. CONCLUSIONS: The experience of pain, in particular severe daily pain, has a substantial negative impact both on labor force participation in Spain as well as reported absenteeism and presenteeism. As a measure of health status, it clearly has an impact that outstrips other health status measures. Whether or not pain is considered as a disease in its own right, the experience of chronic pain, as defined here, presents policy-makers with a major challenge. Programs to relieve the burden of pain in the community clearly have the potential for substantial benefits from societal, individual, and employer perspectives. AD - College of Pharmacy, University of Minnesota, Minneapolis, MN 55455-0343, USA. p8366@msn.com AN - 22017234 AU - Langley, P. C. AU - Tornero Molina, J. AU - Margarit Ferri, C. AU - Pérez Hernández, C. AU - Tejedor Varillas, A. AU - Ruiz-Iban, M. A. DO - 10.3111/13696998.2011.632045 DP - NLM ET - 2011/10/25 IS - 6 KW - *Absenteeism Adolescent Adult Age Factors Comorbidity Efficiency Employment/*statistics & numerical data Female Health Behavior Health Status Health Surveys Humans Male Middle Aged Pain/*epidemiology Severity of Illness Index Socioeconomic Factors Spain/epidemiology Young Adult LA - eng N1 - 1941-837x Langley, Paul C Tornero Molina, Jesús Margarit Ferri, César Pérez Hernández, Concepción Tejedor Varillas, Alejandro Ruiz-Iban, Miguel Angel Journal Article Research Support, Non-U.S. Gov't England J Med Econ. 2011;14(6):835-45. doi: 10.3111/13696998.2011.632045. Epub 2011 Nov 9. PY - 2011 SN - 1369-6998 SP - 835-45 ST - The association of pain with labor force participation, absenteeism, and presenteeism in Spain T2 - J Med Econ TI - The association of pain with labor force participation, absenteeism, and presenteeism in Spain VL - 14 ID - 3750 ER - TY - JOUR AB - BACKGROUND: The purpose of this study is to assess the burden of neuropathic pain (NeP) on health-related quality-of-life (HRQoL), health status, employment status, absenteeism and presenteeism, and direct medical costs in Western Europe. METHODS: Data are from the 2010 National Health and Wellness Survey (NHWS) for five countries in western Europe: the UK, France, Spain, Germany, and Italy. Among subjects who reported experiencing pain in the past month, those who attributed their pain to NeP were compared with those who attributed their pain to another chronic pain condition other than NeP (the latter was the reference group). These two groups were compared on demographic and both pain and non-pain related comorbidities. Generalized linear models were used to estimate the independent contribution of the presence of NeP on: (a) HRQoL (using the SF-12v2); (b) self-reported health status (the first item of the SF-12v2); (c) employment status; (d) absenteeism and presenteeism (using the WPAI questionnaire); and (e) direct medical costs (estimated from self-reported healthcare resource use and unit costs from the literature). RESULTS: Relative to the chronic pain reference group, subjects with NeP reported a higher prevalence of severe daily pain (38.12% vs 12.67%, p < 0.05), lower labor force participation (39.68% vs 55.56%; p < 0.05), higher prevalence of sleep difficulties (59.14% vs 46.73%; p < 0.05), insomnia (45.61% vs 29.78%; p < 0.05) anxiety (42.42% vs 31.99%; p < 0.05), and depression (35.25% vs 24.03%; p < 0.05). NeP subjects reported higher rates of absenteeism (39.78% vs 21.47%; p < 0.05) and presenteeism (86.48% vs. 66.70%; p < 0.050). Direct medical costs were approximately twice as high compared to non-NeP controls. In addition, >80% of NeP patients reported having other pain conditions. Regression results amplified these findings by indicating the independent contribution of confounding factors on the presence of NeP. LIMITATIONS: The NHWS is an Internet-based survey and may not be representative of the respective country populations if Internet access is limited. Second, respondents are asked to report their experience of pain. Although respondents are asked if their pain condition has been diagnosed by a physician there is no separate clinical confirmation of the presence of pain, pain conditions reported, and the presence of comorbidities. CONCLUSIONS: The presence of NeP is associated with an increased disease burden in the chronic pain population. This is seen in terms of HRQoL, health status, employment experience, and direct medical costs. AD - University of Minnesota, Minneapolis, USA. langley@maimonresearch.com AN - 22970839 AU - Langley, P. C. AU - Van Litsenburg, C. AU - Cappelleri, J. C. AU - Carroll, D. DO - 10.3111/13696998.2012.729548 DP - NLM ET - 2012/09/14 IS - 1 KW - *Absenteeism Adolescent Adult Aged Chronic Pain/economics/physiopathology Comorbidity Cost of Illness Employment/*statistics & numerical data Europe Female Health Behavior Health Expenditures/statistics & numerical data Health Services/statistics & numerical data *Health Status Health Surveys Humans Internet Male Middle Aged Neuralgia/*economics/*epidemiology/physiopathology Prevalence *Quality of Life Socioeconomic Factors Surveys and Questionnaires Young Adult LA - eng N1 - 1941-837x Langley, Paul C Van Litsenburg, Chantal Cappelleri, Joseph C Carroll, Dawn Journal Article Research Support, Non-U.S. Gov't England J Med Econ. 2013;16(1):85-95. doi: 10.3111/13696998.2012.729548. Epub 2012 Oct 10. PY - 2013 SN - 1369-6998 SP - 85-95 ST - The burden associated with neuropathic pain in Western Europe T2 - J Med Econ TI - The burden associated with neuropathic pain in Western Europe VL - 16 ID - 3331 ER - TY - JOUR AB - OBJECTIVE: Utah prescription opioid death rates increased nearly fivefold during 2000-2009. Inadequate understanding of risk factors hinders prevention. The goal of this study was to determine risk factors for prescription opioid death in Utah. DESIGN: Case-control study. Cases were 254 Utah decedents with ≥1 prescription opioid causing death during 2008-2009 with nonintentional manner of death (information obtained via next-of-kin interviews). Controls were 1,308 Utah 2008 Behavioral Risk Factor Surveillance System respondents who reported prescription opioid use during the previous year. OUTCOME MEASURES: Exposure prevalence ratios (EPRs) for selected characteristics and confidence intervals (CIs) were calculated. RESULTS: Decedents were more likely than the comparison group to have used prescription pain medication more than prescribed (52.9% vs 3.2%; EPR, 16.5; 95% CI, 9.3-23.7), obtained prescription pain medication from nonprescription sources (39.6% vs 8.3%; EPR, 4.8; 95% CI, 3.6-6.0), smoked daily (54.5% vs 9.7%; EPR, 5.6; 95% CI, 4.4-6.9), not graduated high school (18.5% vs 6.2%; EPR, 3.0; 95% CI, 2.0-3.9), and been divorced or separated (34.6% vs 9.4%; EPR, 3.7; 95% CI, 3.0-4.4). Decedents were more likely to have had chronic pain than the comparison group (94.2% vs 31.6%; EPR, 3.0; 95% CI, 2.7-3.3). CONCLUSIONS: Use of pain medication outside prescription bounds was a risk factor for death. However, decedents were more likely to have had chronic pain, and the majority of both groups had obtained pain medication by prescription. Other factors (e.g., smoking status) might also play important roles in prescription opioid-related death. Prescribers should screen chronic pain patients for risk factors. AD - Utah Department of Health, Salt Lake City, UT, USA. william.lanier@fda.hhs.gov AN - 23137228 AU - Lanier, W. A. AU - Johnson, E. M. AU - Rolfs, R. T. AU - Friedrichs, M. D. AU - Grey, T. C. DA - Dec DO - 10.1111/j.1526-4637.2012.01518.x DP - NLM ET - 2012/11/10 IS - 12 KW - Adolescent Adult Aged Analgesics, Opioid/*poisoning Case-Control Studies Cause of Death Chronic Pain/drug therapy/*epidemiology Drug Overdose/*mortality Educational Status Female Humans Male Marital Status/statistics & numerical data Middle Aged Prescription Drug Misuse Prescription Drugs/*poisoning Risk Factors Smoking/epidemiology Utah/epidemiology Young Adult LA - eng N1 - 1526-4637 Lanier, William A Johnson, Erin M Rolfs, Robert T Friedrichs, Michael D Grey, Todd C Journal Article England Pain Med. 2012 Dec;13(12):1580-9. doi: 10.1111/j.1526-4637.2012.01518.x. Epub 2012 Nov 8. PY - 2012 SN - 1526-2375 SP - 1580-9 ST - Risk factors for prescription opioid-related death, Utah, 2008-2009 T2 - Pain Med TI - Risk factors for prescription opioid-related death, Utah, 2008-2009 VL - 13 ID - 3572 ER - TY - JOUR AB - Background: Headache is a disease that has a high social impact in the paediatric as well as in the adult population, often resulting in a significant reduction in the young patient's quality of life, reflected primarily in a greater number of days off school and increasingly frequent recourse to symptomatic drugs. The idea for this study came from the clinical impression that some paediatric headache patients might benefit more from inpatient than outpatient care. Aim:The aim of our study was to compare the effectiveness of hospitalization to outpatient care of patients with newly diagnosed frequent and disabling headache. Methods: A pragmatic randomized open-label trial was conducted at the Child Neurology Clinic of the University of Pavia, Italy. Children and adolescents with a 2- to 6-month moderate-to-severe migraine or tension-type headache history were randomized to hospital admission or outpatient assessment and followed for 6 months. The efficacy of the two therapeutic strategies was measured by counting the number of responders in each arm. Other end points included the often induce or favour headache attacks. If these mechanisms can be interrupted, the management of disease mean frequency and duration of attacks, the number of drug prescriptions taken to control pain, and the number of patients and physicians expressing satisfaction with treatment. Results: The study population included 27 girls and 23 boys aged 8 through 18 years with migraine (23 cases) or tension-type headache (27 cases). Compared to outpatient assessment, hospital admission was correlated to a significant increase in the number of responders: 0 vs. 44% (1 month), 0 vs. 68% (3 months), and 12 vs. 68% (6 months). The mean frequency and duration of attacks were significantly lower in hospitalized patients (p < 0.0001). Hospitalization was correlated with a significant reduction of patients with severe headache (p < 0.005), a reduction of drug use, and a higher number of satisfied patients and physicians (p < 0.05). Logistic regression analysis confirmed the higher responder rate among hospitalized patients after adjusting for age, sex, diagnosis, and headache characteristics or admission. Conclusions: We think hospitalization reduces the emotional mechanisms that provoke stress in children and may become easier and with enduring benefits. Copyright (c) 2007 S. Karger AG, Basel. AN - WOS:000242283600001 AU - Lanzi, G. AU - D'Arrigo, S. AU - Termine, C. AU - Rossi, M. AU - Ferrari-Ginevra, O. AU - Mongelli, A. AU - Millul, A. AU - Beghi, E. DO - 10.1159/000096383 IS - 1 N1 - Lanzi, G. D'Arrigo, S. Termine, C. Rossi, M. Ferrari-Ginevra, O. Mongelli, A. Millul, A. Beghi, E. d'arrigo, stefano/K-3640-2016; Mir, Pablo/C-8662-2013; Beghi, Ettore/AAA-7426-2020 d'arrigo, stefano/0000-0001-5188-9418; Mir, Pablo/0000-0003-1656-302X; Beghi, Ettore/0000-0003-2542-0469; termine, cristiano/0000-0003-2325-8293; millul, andrea/0000-0002-1013-5668 PY - 2007 SN - 0254-4962 SP - 1-7 ST - The effectiveness of hospitalization in the treatment of paediatric idiopathic headache patients T2 - Psychopathology TI - The effectiveness of hospitalization in the treatment of paediatric idiopathic headache patients UR - ://WOS:000242283600001 VL - 40 ID - 2710 ER - TY - JOUR AB - Seventy adolescents suffering from recurrent tension and migraine headache were compared with headache-free controls on extensive psychosocial, health-behaviour and medical measures, using the students' own reports, parent and teacher assessments and information obtained from school health-records. Headache sufferers reported significantly more somatic symptoms and psychological distress than controls. Differences between the groups' reported anxiety were validated by similar outcomes from parent and teacher assessments. As expected, recurrent headache sufferers were more often absent from school and used the school health-service more than controls. Furthermore, the parents of students with headache were more often divorced and those of students with migraine, in particular, suffered more frequently from headache and abdominal pain. Multivariate analyses indicated that six variables could accurately classify 85 per cent of students as headache sufferers or controls. RÉSUMÉ Le rôAle des facteurs psycho-sociax, de comportement de santé et médicaux dans les maux de tête des adolescents Soixante-dix adolescents souffrant de tensions et migraines récidivantes ont été comparés à des contrôles sans maux de tête sur des mesures variées psychosociales, de comportement de santé et médicales, utilisant les propres déclarations des élèves, l'évaluation des parents et enseignants, et les informations obtenues des carnets de santé scolaires. Ls sujets souffrant de maux de tête faisaient part de symptomes somatiques et de souffrances psychologiques en nombre significativement plus élevé que les contrôles. Les différences dans les taux d'anxiété rapportés par les groupes étaient validées par des conclusions identiques dans les appréciations de parents et enseignants. Comme on pouvait s'y attendre, les sujets souffrant de maux de tête reecidivants étaient plus souvent absents de l'école et faisaient plus souvent appel aux services de santé scolaire que les contrôles. De plus, les parents d'élèves avec maux de tête étaient plus souvent divorcés et ceux des élèves présentant des migraines avaient plus souvent d'autres maux de tête et des douleurs abdominales. Les analyses multavariéees ont indiqué que six variables pouvaient correctement classer 85 pour cent des élèves comme souffrant de maux de tête ou comme contrôles. ZUSAMMENFASSUNG Die Rolle psychosozialer, gesundheitlicher und medizinischer Faktoren bei Kopfschmerzen bei Jugendlichen 70 Jugendliche mit rezidivierenden Spannungs- und Migrainelkopfschmerzen wurden anhand extensiver psychosozialer, gesundheitlicher und medizinischer Parameter mit Kontrollen ohne Kopffschmerzen verrglichen, indem eigene Berichte der Studenten, Beurteilungen von Eltern und Lehrern und Informationen von Schuluntersuchungen ausgewertet wurden. Unterschiede der von den Gruppen dargestellten Ängste konnten durch Parallelen in den Beurteilungen von Eltern and Lehrern belegt werden. Wie vermutet fehlten die unter Kopfschmerzen Leidenden häufiger in der Schule und nahmen häufiger den Schularzt in Anspruch als die Kontrollen. Außerdem waren die Eltern von Studenten mit Kopfschmerzen häufiger geschieden und insbesondere die von Studenten mit Migraine litten oft unter Kopf- und Bauchschmerzen. Multivarianzanalysen haben gezeigt, daß 85 Prozent der Studenten durch sechs Variablen genau in Jugendliche mit Kopfschmerzen und Kontrollen differenziert werden konnten. RESUMEN El papel de los factores psicosociales, comportamiento de salud y factores médicos en la cefalea del adolescente Setenta adolescentes que sufrian dolor de cabeza de tension y migrailas fueron comporados con controles sin cefalea por lo que respecta a medidas psicosociales, comportamiento de salud y medidas médicas, utilizando los relatos de los mismos estudiantes, las valoraciones de padres y maestros y la información obtenida de los registros de salud de la escuela. Los que sufrían dolor de cabeza tenian significativamente más síntomas somáticos y problemas psicológicos que los ontroles. Las diferencias entre los grupos mostraron que la evaluación de la ansiedad era similar según los padres como según los maestros. Como era de esperar los que sufrían dolor de cabeza recurrente estaban más ausentes de la escuela y utilizaban más los servicios de salud de la escuela que los controles. Por otra parte los padres de estudiantes con dolor de cabeza eran con mayor frecuencia divorciados y los de los estudiantes cn migraña en particular sufrian con mayor frecuencia cefalea y dolor abdominal. Los análisis multivariados indicaban que seis variables podian clasificar cuidadosamente el 85 por ciento de los estudiantes como sufrientes de cefalea o como controles. AU - Larsson, Bo DA - 1988 DO - 10.1111/j.1469-8749.1988.tb04799.x DP - Wiley Online Library IS - 5 LA - en PY - 1988 SN - 1469-8749 SP - 616-625 ST - The Role of Psychological, Health-Behaviour and Medical Factors in Adolescent Headache T2 - Developmental Medicine & Child Neurology TI - The Role of Psychological, Health-Behaviour and Medical Factors in Adolescent Headache UR - https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1469-8749.1988.tb04799.x https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1469-8749.1988.tb04799.x?casa_token=SKc7oXkGZSoAAAAA:LjBdkXkWlYgadwUxP_thYh0AdOKmj_g64Drea9Co9ZH-CMOF_O05_B95JlpydFijTv3LqMWujg6MOfsl VL - 30 Y2 - 2021/06/09/18:32:47 ID - 6 ER - TY - JOUR AB - Compared the efficacy of a school-based, nurse-administered relaxation training intervention to a no-treatment control condition for children (10-15 years old) with chronic tension-type headache and the outcome at posttreatment and a 6-month follow-up. The study was conducted in a controlled between-group design including 26 schoolchildren who were randomly assigned to the two treatment conditions. Results showed that headache activity in the children treated with relaxation training was significantly more reduced than among those in the no-treatment control group at posttreatment as well as the 6-month follow-up. At these evaluations, 69% and 73% of the pupils, respectively, treated with relaxation had achieved a clinically significant headache improvement (at least a 50% improvement) as compared to 8% and 27% of the pupils, respectively, in the no-treatment control group. Thus, a school-based, nurse-administered relaxation training program seems to be a viable treatment approach for children with chronic tension-type headaches. AU - Larsson, B. AU - Carlsson, J. DA - 1996/10// DO - 10.1093/jpepsy/21.5.603 DP - PubMed IS - 5 J2 - J Pediatr Psychol KW - Adolescent Child Chronic Disease Female Follow-Up Studies Headache Humans Male Relaxation Therapy School Nursing Treatment Outcome LA - eng PY - 1996 SN - 0146-8693 SP - 603-614 ST - A school-based, nurse-administered relaxation training for children with chronic tension-type headache T2 - Journal of Pediatric Psychology TI - A school-based, nurse-administered relaxation training for children with chronic tension-type headache UR - http://www.ncbi.nlm.nih.gov/pubmed/8936891 VL - 21 ID - 133 ER - TY - JOUR AB - BACKGROUND: In recent reviews of psychological and drug treatment, relaxation training approaches have been found to be efficacious for children and adolescents suffering from recurrent tension-type headache (TTH), while biofeedback procedures provide effective help for migraine headache sufferers, primarily treated in tertiary clinics. OBJECTIVE: In a school-based replication series, the effectiveness and efficiency of relaxation training provided within school settings were examined, in addition to the effects on various headache features and the maintenance of treatment gains at a 6 to 10-month follow-up. METHODS: Over a 20-year period, 288 adolescents aged 10 to 18 years participated in seven randomized, controlled trials conducted within regular school health service settings. Subjects were included if they had suffered from frequent migraine or TTHs, or from both headache types for at least 1 year. Various formats of standardized relaxation training procedures were contrasted to different attention-control (ATCO) approaches or self-monitoring (SM) of headaches in prospective diary recordings. RESULTS: The results showed that a therapist-administered relaxation approach was superior to self-help or school-nurse administered relaxation training approaches, ATCO conditions or SM of headaches. Students with TTHs responded positively to any form of relaxation training, whereas those with frequent migraine responded well only to therapist-administered relaxation. However, school-nurse administered procedures were found to be the most efficient form of relaxation treatment, in particular for adolescents suffering from TTHs. Total headache activity, the number of headache days and peak headache intensity were significantly reduced after relaxation treatment, in addition to medication usage. Treatment gains were well maintained at the 6 to 10-month follow-up. CONCLUSION: Therapist-assisted relaxation training is an effective treatment for adolescents suffering from frequent TTHs or migraine. However, such treatment administered by school-nurses administered within school health care settings is an efficient treatment approach for adolescents suffering from the most common form of primary headache, ie, TTHs. AU - Larsson, Bo AU - Carlsson, Jane AU - Fichtel, Asa AU - Melin, Lennart DA - 2005/06// DO - 10.1111/j.1526-4610.2005.05138.x DP - PubMed IS - 6 J2 - Headache KW - Adolescent Child Humans Migraine Disorders Prospective Studies Recurrence Relaxation Therapy School Nursing Schools Sweden Tension-Type Headache LA - eng PY - 2005 SN - 0017-8748 SP - 692-704 ST - Relaxation treatment of adolescent headache sufferers T2 - Headache TI - Relaxation treatment of adolescent headache sufferers: results from a school-based replication series UR - http://www.ncbi.nlm.nih.gov/pubmed/15953302 VL - 45 ID - 131 ER - TY - JOUR AB - This study compared the relative efficacy of a therapist-assisted relaxation treatment programme with a self-help approach and a self-monitoring condition in the treatment of chronic headaches in adolescents within a school setting. The subjects were 46 high school students, 16-18 years of age, who were randomly assigned to the three treatment conditions. The results indicated that the self-help approach was as effective as the therapist-assisted relaxation condition in reducing the students' headache, and that these findings were maintained at a 5-month follow-up evaluation. The results suggest that the self-help relaxation procedure is a potential low-cost alternative treatment to a more traditional therapist-based intervention condition. AU - Larsson, B. AU - Daleflod, B. AU - Håkansson, L. AU - Melin, L. DA - 1987/01// DO - 10.1111/j.1469-7610.1987.tb00657.x DP - PubMed IS - 1 J2 - J Child Psychol Psychiatry KW - Adolescent Cost-Benefit Analysis Female Follow-Up Studies Headache Humans Male Patient Compliance Relaxation Therapy School Health Services Self Care LA - eng PY - 1987 SN - 0021-9630 SP - 127-136 ST - Therapist-assisted versus self-help relaxation treatment of chronic headaches in adolescents T2 - Journal of Child Psychology and Psychiatry, and Allied Disciplines TI - Therapist-assisted versus self-help relaxation treatment of chronic headaches in adolescents: a school-based intervention UR - http://www.ncbi.nlm.nih.gov/pubmed/3104371 VL - 28 ID - 134 ER - TY - JOUR AB - An experimental study was conducted on 33 adolescent students with various types of chronic headaches (tension and combined tension and migraine headaches), all treated in a school setting. After a 4-week baseline period during which the subjects rated their headache activity, they were randomly assigned to a 9-session relaxation training programme or to an information-contact condition, both contrasted with an untreated self-registration group. Relaxation therapy alone led to significant improvement in headache activity, particularly in reduction of the frequency of complaints which still was significantly reduced at a 6-month follow-up evaluation. The effects obtained in the information-contact condition were comparable to those in the self-registration group, both achieving only minor improvements after treatment or at the follow-up assessment. The majority of students in the relaxation treatment, however, was much improved, attaining more than 50% reduction in headache activity. The findings in the present study are consistent with results from similar treatment outcome studies, reported on adult populations with chronic headaches, and demonstrate that relaxation training programmes can be of substantial help in a school setting. AU - Larsson, Bo AU - Melin, Lennart DA - 1986/06// DO - 10.1016/0304-3959(86)90236-8 DP - PubMed IS - 3 J2 - Pain KW - Adolescent Chronic Disease Female Follow-Up Studies Headache Humans Male Migraine Disorders Muscle Relaxation Relaxation Therapy School Health Services Stress, Psychological LA - eng PY - 1986 SN - 0304-3959 SP - 325-336 ST - Chronic headaches in adolescents T2 - Pain TI - Chronic headaches in adolescents: treatment in a school setting with relaxation training as compared with information-contact and self-registration UR - http://www.ncbi.nlm.nih.gov/pubmed/3528989 VL - 25 ID - 135 ER - TY - JOUR AB - A sample of 108 adolescent students suffering from migraine and tension headaches, treated with relaxation training and attention-control approaches, were evaluated at 5-6 month and 3-4 year follow-ups. Data were obtained for 69% (75) of the original subjects at the second follow-up. The treatments administered within a school setting were contrasted with students' self-monitoring of headache. The results indicated that students treated with relaxation training showed a good maintenance of posttreatment headache reduction at the two follow-up evaluations, 80% and 85%, respectively. Although treatment condition and level of pretreatment headache were associated with a favorable outcome at the 5-6 month follow-up, only baseline headache severity emerged as a significant predictor at the final follow-up. Several variables from the psychological functioning and health behavioral domains found to predict posttreatment outcome for the adolescent headache sufferers in previous research, did not contribute significantly to outcome at the follow-ups. AN - 2654069 AU - Larsson, B. AU - Melin, L. DA - Apr DO - 10.1111/j.1526-4610.1989.hed22904250.x DP - NLM ET - 1989/04/01 IS - 4 KW - Adolescent *Behavior Therapy Female Follow-Up Studies Headache/*therapy Humans Male Prognosis Recurrence Relaxation Therapy LA - eng N1 - Larsson, B Melin, L Journal Article United States Headache. 1989 Apr;29(4):250-4. doi: 10.1111/j.1526-4610.1989.hed22904250.x. PY - 1989 SN - 0017-8748 (Print) 0017-8748 SP - 250-4 ST - Follow-up on behavioral treatment of recurrent headache in adolescents T2 - Headache TI - Follow-up on behavioral treatment of recurrent headache in adolescents VL - 29 ID - 3459 ER - TY - JOUR AB - Forty-eight adolescents suffering from recurrent tension headache participated in a controlled trial conducted in a high school setting. During the first treatment phase self-help relaxation training was compared with a waiting-list group. Following this phase a pharmacological regimen consisting of a muscle relaxant (chlormezanone) and placebo was superimposed on relaxation therapy in a double-blind crossover design. Each treatment phase encompassed a 5-week period. In addition to the evaluation of headache complaints, psychological distress among students was measured with respect to their experience of somatic complaints, depressive, anxiety and stress symptoms. Although self-help relaxation training significantly decreased the severity and annoyance of adolescents' headache besides their somatic complaints, the clinical improvement of headache was modest. The addition of chlormezanone did not help those who were nonresponders to self-help relaxation training. Finally, a set of pretreatment variables consisting of baseline headache severity and annoyance, experience of anxiety and daily life stress among adolescents could predict outcome of self-help relaxation therapy. AD - Department of Child & Youth Psychiatry, Uppsala University Hospital, Sweden. AN - 2272819 AU - Larsson, B. AU - Melin, L. AU - Döberl, A. DA - Oct DO - 10.1111/j.1526-4610.1990.hed3010665.x DP - NLM ET - 1990/10/01 IS - 10 KW - Adolescent Chlormezanone/*therapeutic use Female Headache/psychology/*therapy Humans Male Recurrence *Relaxation Therapy Self Care LA - eng N1 - Larsson, B Melin, L Döberl, A Clinical Trial Journal Article Randomized Controlled Trial United States Headache. 1990 Oct;30(10):665-71. doi: 10.1111/j.1526-4610.1990.hed3010665.x. PY - 1990 SN - 0017-8748 (Print) 0017-8748 SP - 665-71 ST - Recurrent tension headache in adolescents treated with self-help relaxation training and a muscle relaxant drug T2 - Headache TI - Recurrent tension headache in adolescents treated with self-help relaxation training and a muscle relaxant drug VL - 30 ID - 3429 ER - TY - JOUR AB - In a one-year longitudinal study, emotional/behavioural correlates and predictors of four common pain complaints (headaches, stomach, back and limb pain), were examined in a representative school sample of 2360 adolescents aged 12- to 15-years. At first assessment, 18.3% reported being bothered by a frequent pain (at least once a week) and 40% of the pain sufferers had two or more pain locations, more commonly reported by girls. Subjects having any of the four frequent pains reported having fewer friends and were more often absent from school. Frequency and number of reported pains among adolescents were positively related to levels of internalising and externalising problems. These latter problems were consistently and significantly higher among adolescents with frequent back and limb pains, however, when coexistence of another frequent pain was controlled, differences were small. Number of pains at the one-year follow-up was significantly predicted by frequent back pain and headache, depressive symptoms scores, somatic complaints (other than pain), number of friends and reduced leisure time activities during the follow-up period. Frequent back pain and depressive symptoms also predicted multiple frequent pains (vs single frequent pain) at the follow-up as did recent parental divorce. It is concluded that various emotional and behavioural problems, and which are commonly regarded as being specifically related to pain type or location among adolescents, depend rather on frequency and coexistence of multiple frequent pains. Assessment of adolescents with frequent and multiple pains should, therefore, include broad screening of internalising as well as externalising problems as well as various aspects of impairment. (C) 2006 European Federation of Chapters of the International Association for the Study of Pain. Published by Elsevier Ltd. All rights reserved. AN - WOS:000242378400007 AU - Larsson, B. AU - Sund, A. M. DA - Jan DO - 10.1016/j.ejpain.2005.12.014 IS - 1 N1 - Larsson, Bo Sund, Anne Mari PY - 2007 SN - 1090-3801 SP - 57-65 ST - Emotional/behavioural, social correlates and one-year predictors of frequent pains among early adolescents: Influences of pain characteristics T2 - European Journal of Pain TI - Emotional/behavioural, social correlates and one-year predictors of frequent pains among early adolescents: Influences of pain characteristics UR - ://WOS:000242378400007 VL - 11 ID - 2708 ER - TY - JOUR AB - Purpose of the study Hip disease can produce major pain and functional disorders in children who should benefit from total hip arthroplasty. We report our experience with total hip prostheses implanted without cement in children. Material and methods We performed 17 total hip arthroplasties in 13 children who had various conditions, mainly chronic juvenile osteoarthritis and aseptic osteonecrosis secondary to sickle cell anemia. The acetabular inserts were not cemented. All the femoral stems were custom-made using computer-assisted preoperative planning based on standard x-rays and computed tomography findings. Outcome was assessed on the basis of patient satisfaction, pain, and function. Radiographically, we assessed stem implantation, stability and integration. Results were classed with the Harris score and also with the Steinbrocker classification in order to take into account the child's overall functional handicap. Results Mean follow-up was 36.4 months. There were three cases of superficial hematoma, one case of superficial sepsis and one acetabular loosening. All patients were satisfied. Unsatisfactory function, observed in 80 % of the children preoperatively, was found in only 17 % postoperatively. The Harris score improved from 23.8 preoperatively to 87.7 at last follow-up. There were no cases of stem loosening and integration was achieved in 85.3 % of the cases proximally in the area with hydroxyapatite surfacing. Discussion The problem with these children is to determine when total hip arthroplasty should be proposed. We retain three important indications: uncontrollable chronic pain, normal school attendance impossible, no other possibility for conservative surgery. Several studies have reported only mediocre results with cemented stems. We opted for custom-made stems without cement for three reasons: preservation of bone stock, better adaptation to bone whose quality and morphology had been remodeled by the underlying condition and repeated osteotomies which also affect the gluteus medius, and finally, better chance of success for future revisions in these active young patients. Conclusion The question on whether or not total hip arthroplasty should be performed early in these children to avoid osteotomies which could alter the longevity of a future prosthesis remains open. Custom-made stems inserted without cement have provided satisfactory results in our experience. To date, follow-up is too short to compare our results with those obtained by others using cemented stems. AN - WOS:000178456000003 AU - Launay, F. AU - Jouve, J. L. AU - Guillaume, J. M. AU - Viehweger, E. AU - Jacquemier, M. AU - Bollini, G. DA - Sep IS - 5 N1 - Launay, F Jouve, JL Guillaume, JM Viehweger, E Jacquemier, M Bollini, G Viehweger, Elke/AAK-2321-2020 Viehweger, Elke/0000-0001-6639-4557 PY - 2002 SN - 0035-1040 SP - 460-466 ST - Total hip arthroplasty in children and adolescents: 17 cases T2 - Revue De Chirurgie Orthopedique Et Reparatrice De L Appareil Moteur TI - Total hip arthroplasty in children and adolescents: 17 cases UR - ://WOS:000178456000003 VL - 88 ID - 2826 ER - TY - JOUR AB - OBJECTIVE: To describe the importance of tension-type headache (TTH) in Santiago, Chile, by analyzing its prevalence, clinical features, and impact by age, gender, and socioeconomic status, using widely accepted international diagnostic criteria. METHODS: In 1993, a representative sample of 1540 adults (older than 14) of the province of Santiago were interviewed using a standard questionnaire. A total of 1385 (89.9% response rate) subjects responded to the survey. Initially, a designated member of each household responded to the questionnaire. Subsequently, each household member with headache was asked to respond to questions about the severity, frequency, location, duration, associated symptoms, and impact in work and social activities of their most frequent headaches. TTH diagnoses were determined in accordance with the International Headache Society criteria of 1988. RESULTS: Total prevalence was found to be 26.9% (95% CI: 24.6-29.3%); 35.2% in females (95% CI: 31.7-38.8%) and 18.1% in males (95% CI: 15.2-21.3%). The prevalence of episodic TTH was 24.3% (95% CI: 22.1-26.7%) and of chronic TTH 2.6% (95% CI: 1.8-3.6%). Overall, and by subtype, prevalence was significantly higher in females (ratio 1:9). There was no significant variation in prevalence by socioeconomic or age group except in chronic TTH, in which there was an increase with age. CONCLUSIONS: TTH is a prevalent condition in a sample of adults of Santiago, similar to that reported in previous studies using similar methodologies. Overall, TTH represents 72.3% of all recurrent headaches. AD - Institute of Neurosurgery, East Metropolitan Health Service, Santiago, Chile. AN - 9827247 AU - Lavados, P. M. AU - Tenhamm, E. DA - Oct DO - 10.1046/j.1468-2982.1998.1808552.x DP - NLM ET - 1998/11/25 IS - 8 KW - Absenteeism Adolescent Adult Aged Chile/epidemiology Comorbidity Female Humans Male Middle Aged Nausea/epidemiology Prevalence Sampling Studies Socioeconomic Factors Tension-Type Headache/*epidemiology Urban Population LA - eng N1 - Lavados, P M Tenhamm, E Journal Article Research Support, Non-U.S. Gov't England Cephalalgia. 1998 Oct;18(8):552-8. doi: 10.1046/j.1468-2982.1998.1808552.x. PY - 1998 SN - 0333-1024 (Print) 0333-1024 SP - 552-8 ST - Epidemiology of tension-type headache in Santiago, Chile: a prevalence study T2 - Cephalalgia TI - Epidemiology of tension-type headache in Santiago, Chile: a prevalence study VL - 18 ID - 3435 ER - TY - JOUR AB - Background Psychological therapies for parents of children and adolescents with chronic illness aim to improve parenting behavior and mental health, child functioning (behavior/disability, mental health, and medical symptoms), and family functioning. This is an updated version of the original Cochrane Review (2012) which was first updated in 2015. Objectives To evaluate the efficacy and adverse events of psychological therapies for parents of children and adolescents with a chronic illness. Search methods We searched CENTRAL, MEDLINE, Embase, PsycINFO, and trials registries for studies published up to July 2018. Selection criteria Included studies were randomized controlled trials (RCTs) of psychological interventions for parents of children and adolescents with a chronic illness. In this update we included studies with more than 20 participants per arm. In this update, we included interventions that combined psychological and pharmacological treatments. We included comparison groups that received either non-psychological treatment (e.g. psychoeducation), treatment as usual (e.g. standard medical care without added psychological therapy), or wait-list. Data collection and analysis We extracted study characteristics and outcomes post-treatment and at first available follow-up. Primary outcomes were parenting behavior and parent mental health. Secondary outcomes were child behavior/disability, child mental health, child medical symptoms, and family functioning. We pooled data using the standardized mean difference (SMD) and a random-effects model, and evaluated outcomes by medical condition and by therapy type. We assessed risk of bias per Cochrane guidance and quality of evidence using GRADE. Main results We added 21 new studies. We removed 23 studies from the previous update that no longer met our inclusion criteria. There are now 44 RCTs, including 4697 participants post-treatment. Studies included children with asthma (4), cancer (7), chronic pain (13), diabetes (15), inflammatory bowel disease (2), skin diseases (1), and traumatic brain injury (3). Therapy types included cognitive-behavioural therapy (CBT; 21), family therapy (4), motivational interviewing (3), multisystemic therapy (4), and problem-solving therapy (PST; 12). We rated risk of bias as low or unclear for most domains, except selective reporting bias, which we rated high for 19 studies due to incomplete outcome reporting. Evidence quality ranged from very low to moderate. We downgraded evidence due to high heterogeneity, imprecision, and publication bias. Evaluation of parent outcomes by medical condition Psychological therapies may improve parenting behavior (e.g. maladaptive or solicitous behaviors; lower scores are better) in children with cancer post-treatment and follow-up (SMD -0.28, 95% confidence interval (CI) -0.43 to -0.13; participants = 664; studies = 3; SMD -0.21, 95% CI -0.37 to -0.05; participants = 625; studies = 3; 1 2 = 0%, respectively, low-quality evidence), chronic pain post-treatment and follow-up (SMD -0.29, 95% CI -0.47 to -0.10; participants = 755; studies = 6; SMD -0.35, 95% CI -0.50 to -0.20; participants = 678; studies = 5, respectively, moderate-quality evidence), diabetes post-treatment (SMD -1.39, 95% CI - 2.41 to -0.38; participants = 338; studies = 5, very low-quality evidence), and traumatic brain injury post-treatment (SMD -0.74, 95% CI -1.25 to -0.22; participants = 254; studies = 3, very low-quality evidence). For the remaining analyses data were insufficient to evaluate the effect of treatment. Psychological therapies may improve parent mental health (e.g. depression, anxiety, lower scores are better) in children with cancer post-treatment and follow-up (SMD -0.21, 95% CI -0.35 to -0.08; participants = 836, studies = 6, high-quality evidence; SMD - 0.23, 95% CI -0.39 to -0.08; participants = 667; studies = 4, moderate-quality evidence, respectively), and chronic pain post-treatment and follow-up (SMD -0.24, 95% CI -0.42 to -0.06; participants = 490; studies = 3; SMD -0.20, 95% CI -0.38 to - 0.02; participants = 482; studies = 3, respectively, low-quality evidence). Parent mental health did not improve in studies of children with diabetes post-treatment (SMD -0.24, 95% CI -0.90 to 0.42; participants = 211; studies = 3, very low-quality evidence). For the remaining analyses, data were insufficient to evaluate the effect of treatment on parent mental health. Evaluation of parent outcomes by psychological therapy type CBT may improve parenting behavior post-treatment (SMD -0.45, 95% CI -0.68 to -0.21; participants = 1040; studies = 9, low-quality evidence), and follow-up (SMD -0.26, 95% CI -0.42 to -0.11; participants = 743; studies = 6, moderate-quality evidence). We did not find evidence for a beneficial effect for CBT on parent mental health at post-treatment or follow-up (SMD -0.19, 95% CI - 0.41 to 0.03; participants = 811; studies = 8; SMD -0.07, 95% CI -0.34 to 0.20; participants = 592; studies = 5; respectively, very low-quality evidence). PST may improve parenting behavior post-treatment and follow-up (SMD -0.39, 95% CI -0.64 to -0.13; participants = 947; studies = 7, low-quality evidence; SMD -0.54, 95% CI -0.94 to -0.14; participants = 852; studies = 6, very low-quality evidence, respectively), and parent mental health post-treatment and follow-up (SMD -0.30, 95% CI -0.45 to -0.15; participants = 891; studies = 6; SMD -0.21, 95% CI -0.35 to -0.07; participants = 800; studies = 5, respectively, moderate-quality evidence). For the remaining analyses, data were insufficient to evaluate the effect of treatment on parent outcomes. Adverse events We could not evaluate treatment safety because most studies (32) did not report on whether adverse events occurred during the study period. In six studies, the authors reported that no adverse events occurred. The remaining six studies reported adverse events and none were attributed to psychological therapy. We rated the quality of evidence for adverse events as moderate. Authors' conclusions Psychological therapy may improve parenting behavior among parents of children with cancer, chronic pain, diabetes, and traumatic brain injury. We also found beneficial effects of psychological therapy may also improve parent mental health among parents of children with cancer and chronic pain. CBT and PST may improve parenting behavior. PST may also improve parent mental health. However, the quality of evidence is generally low and there are insufficient data to evaluate most outcomes. Our findings could change as new studies are conducted. AN - WOS:000462935200039 AU - Law, E. AU - Fisher, E. AU - Eccleston, C. AU - Palermo, T. M. C7 - Cd009660 DO - 10.1002/14651858.CD009660.pub4 IS - 3 N1 - Law, Emily Fisher, Emma Eccleston, Christopher Palermo, Tonya M. 1361-6137 PY - 2019 SN - 1469-493X ST - Psychological interventions for parents of children and adolescents with chronic illness T2 - Cochrane Database of Systematic Reviews TI - Psychological interventions for parents of children and adolescents with chronic illness UR - ://WOS:000462935200039 ID - 1967 ER - TY - JOUR AB - Objective To quantify the effects of parent- and family-based psychological therapies for youth with common chronic medical conditions on parent and family outcomes (primary aim) and child outcomes (secondary aim). Methods MEDLINE, EMBASE, and PsycINFO were searched from inception to April 2013. 37 randomized controlled trials were included. Quality of the evidence was evaluated using GRADE criteria. Data were extracted on parent, family, and child outcomes. Results Pooled psychological therapies had a positive effect on parent behavior at posttreatment and follow-up; no significant improvement was observed for other outcome domains. Problem-solving therapy (PST) improved parent mental health and parent behavior at posttreatment and follow-up. There was insufficient evidence to evaluate cognitive-behavioral and systems therapies for many outcome domains. Conclusions Parent-and family-based psychological therapies can improve parent outcomes, with PST emerging as particularly promising. Future research should incorporate consensus statements for outcomes assessment, multisite recruitment, and active comparator conditions. AN - WOS:000343398100007 AU - Law, E. F. AU - Fisher, E. AU - Fales, J. AU - Noel, M. AU - Eccleston, C. DA - Sep DO - 10.1093/jpepsy/jsu032 IS - 8 N1 - Law, Emily F. Fisher, Emma Fales, Jessica Noel, Melanie Eccleston, Christopher Eccleston, Christopher/0000-0003-0698-1543; Fisher, Emma/0000-0001-8980-3181 1465-735x Si PY - 2014 SN - 0146-8693 SP - 866-886 ST - Systematic Review and Meta-Analysis of Parent and Family-Based Interventions for Children and Adolescents With Chronic Medical Conditions T2 - Journal of Pediatric Psychology TI - Systematic Review and Meta-Analysis of Parent and Family-Based Interventions for Children and Adolescents With Chronic Medical Conditions UR - ://WOS:000343398100007 VL - 39 ID - 2291 ER - TY - JOUR AB - The novel coronavirus disease (COVID-19) has caused prolonged disruptions in daily life for many communities. Little is known about the impact of the COVID-19 pandemic on the health and well-being of youth with chronic pain and their families. We conducted a longitudinal, mixed-methods study to characterize early adaptation to the COVID-19 pandemic among 250 families of youth (ages 12-21 years) diagnosed with chronic headache (64%) or other chronic pain conditions (36%) and to determine whether direct exposures to COVID-19 and secondary economic stress modified symptom trajectories. Youth and parents reported on pain interference, anxiety, depression, and insomnia symptoms at 4 waves of data collection from April 2020 to July 2020. We also collected qualitative data on the impact of the pandemic on the youth's pain problem. Nearly half of our sample (49.6%) experienced direct exposures to COVID-19. Secondary economic stress was also common, affecting 44.4% of families. Symptom trajectories for pain, insomnia, depression, and anxiety remained stable or improved for most participants, indicating adaptive adjustment. However, overall symptom burden was high with persistent and clinically elevated depression, anxiety, and insomnia symptoms common among youth and parents. Direct exposures to COVID-19 did not modify symptom trajectories. However, youth pain interference and parent insomnia worsened in families who experienced secondary economic stress. Qualitative data revealed perceived benefits and harms from school closures on the youth's pain problem. Our findings of high symptom burden suggest that pediatric pain clinicians should offer distance assessment and treatment (eg, through telemedicine) to avoid pandemic-related disruptions in pain care. AD - Center for Child Health, Behavior and Development, Seattle Children's Research Institute Seattle, WA, United States, Department of Anesthesiology and Pain Medicine, University of Washington School of Medicine Seattle, WA, United States, Department of Pediatrics, University of Washington School of Medicine, Seattle, WA, United States. AN - 34050112 AU - Law, E. F. AU - Zhou, C. AU - Seung, F. AU - Perry, F. AU - Palermo, T. M. DA - Apr 2 DO - 10.1097/j.pain.0000000000002290 DP - NLM ET - 2021/05/30 LA - eng N1 - 1872-6623 Law, Emily F Zhou, Chuan Seung, Fiona Perry, Frankie Palermo, Tonya M Journal Article United States Pain. 2021 Apr 2. doi: 10.1097/j.pain.0000000000002290. PY - 2021 SN - 0304-3959 ST - Longitudinal study of early adaptation to the coronavirus disease pandemic among youth with chronic pain and their parents: effects of direct exposures and economic stress T2 - Pain TI - Longitudinal study of early adaptation to the coronavirus disease pandemic among youth with chronic pain and their parents: effects of direct exposures and economic stress ID - 4046 ER - TY - JOUR AB - BACKGROUND: The impact of irritable bowel syndrome (IBS) on health-care resource use in France is evaluated, and explanatory variables determined. METHODS: A questionnaire comprising socio-demographic characteristics, symptoms, consumption of resources, quality of life and impact of IBS on productivity was administered by telephone to a sample of 253 French adults with IBS recruited from the general population, and diagnosed with IBS using several well-known diagnostic criteria. The medical costs were estimated on a monthly basis and included medication(s), physicians' consultations, investigations and hospitalizations. RESULTS: Mean age was 48.3 years and 75% of subjects were women (192). Thirty-six percent of subjects had suffered from IBS for more than 10 years; 77% had consulted a general practitioner and 43% a gastroenterologist. Twenty-nine percent of subjects had undergone an investigation and 25% reported hospitalization; 61% of patients reported that they were taking medication. The average monthly medical costs was 71.8 euros (95% CI = [57.6-86.0]) with an asymmetric distribution (median = 28.1 euros) because of a high proportion of subjects (27%) who reported receiving no care at all. The two principal cost components were investigations (39%), and hospitalizations (22%). The highest medical costs were associated with subjects who were very elderly or suffered from severe symptoms (very severe pain), and were correlated with the lowest quality of life scores. CONCLUSION: IBS has a major impact on resource consumption and the productivity of patients. Determination of the variables to explain medical costs showed that advanced age, severe pain and deterioration in quality of life could be predictive of high medical costs. AD - Université Paris-Dauphine and CLP Santé, Paris, France. claude.lepen@clp-sante.fr AN - 15125465 AU - Le Pen, C. AU - Ruszniewski, P. AU - Gaudin, A. F. AU - Amouretti, M. AU - Bommelaer, G. AU - Frexinos, J. AU - Poynard, T. AU - Maurel, F. AU - Priol, G. AU - Bertin, C. DA - Apr DO - 10.1080/00365520310008458 DP - NLM ET - 2004/05/06 IS - 4 KW - *Absenteeism Adolescent Adult Aged Aged, 80 and over *Cost of Illness Female France *Health Care Costs Health Care Surveys Humans Irritable Bowel Syndrome/*economics/psychology Male Middle Aged Quality of Life/psychology LA - eng N1 - Le Pen, C Ruszniewski, P Gaudin, A F Amouretti, M Bommelaer, G Frexinos, J Poynard, T Maurel, F Priol, G Bertin, C Journal Article Research Support, Non-U.S. Gov't England Scand J Gastroenterol. 2004 Apr;39(4):336-43. doi: 10.1080/00365520310008458. PY - 2004 SN - 0036-5521 (Print) 0036-5521 SP - 336-43 ST - The burden cost of French patients suffering from irritable bowel syndrome T2 - Scand J Gastroenterol TI - The burden cost of French patients suffering from irritable bowel syndrome VL - 39 ID - 3695 ER - TY - JOUR AB - Background/Aims: The registry ClinicalTrials.gov was created to provide investigators and patients an accessible database of relevant clinical trials. Methods: To understand the state of sickle cell disease clinical trials, a comprehensive review of all 174 closed, interventional sickle cell trials registered at ClinicalTrials.gov was completed in January 2015. Results: The majority of registered sickle cell disease clinical trials listed an academic center as the primary sponsor and were an early phase trial. The primary outcome for sickle cell disease trials focused on pain (23%), bone marrow transplant (BMT) (13%), hydroxyurea (8%), iron overload (8%), and pulmonary hypertension (8%). A total of 52 trials were listed as terminated or withdrawn, including 25 (14% of all trials) terminated for failure to enroll participants. At the time of this review, only 19 trials uploaded results and 29 trials uploaded a manuscript in the ClinicalTrials.gov database. A systematic review of pubmed.gov revealed that only 35% of sickle cell studies completed prior to 2014 resulted in an identified manuscript. In comparison, of 80 thalassemia trials registered in ClinicalTrials.gov, four acknowledged failure to enroll participants as a reason for trial termination or withdrawal, and 48 trials (60%) completed prior to 2014 resulted in a currently identified manuscript. Conclusion: ClinicalTrials.gov can be an important database for investigators and patients with sickle cell disease to understand the current available research trials. To enhance the validity of the website, investigators must update their trial results and upload trial manuscripts into the database. This study, for the first time, quantifies outcomes of sickle cell disease trials and provides support to the belief that barriers exist to successful completion, publication, and dissemination of sickle cell trial results. AN - WOS:000364826800004 AU - Lebensburger, J. D. AU - Hilliard, L. M. AU - Pair, L. E. AU - Oster, R. AU - Howard, T. H. AU - Cutter, G. R. DA - Dec DO - 10.1177/1740774515590811 IS - 6 N1 - Lebensburger, Jeffrey D. Hilliard, Lee M. Pair, Lauren E. Oster, Robert Howard, Thomas H. Cutter, Gary R. Oster, Robert/0000-0002-2247-8596 1740-7753 PY - 2015 SN - 1740-7745 SP - 575-583 ST - Systematic review of interventional sickle cell trials registered in ClinicalTrials.gov T2 - Clinical Trials TI - Systematic review of interventional sickle cell trials registered in ClinicalTrials.gov UR - ://WOS:000364826800004 VL - 12 ID - 2204 ER - TY - JOUR AB - OBJECTIVE: To determine the feasibility, safety, and effectiveness of the subcutaneous route of fentanyl administration by Basic Life Support-Emergency Medical Technicians (BLS-EMT) in a rural and suburban region, with the support of an online pain management medical control center. METHODS: Retrospective study of patients who received subcutaneous fentanyl and were transported by BLS-EMT to the emergency department (ED) of an academic hospital between July 1, 2013 and January 1, 2014, inclusively. Fentanyl orders were obtained from emergency physicians via an online medical control (OLMC) center. Effectiveness was defined by changes in pain scores 15 minutes, 30 minutes, and 45+ minutes after initial fentanyl administration. Safety was evaluated by measuring vital signs, Ramsay sedation scores, and adverse events subsequent to fentanyl administration. Feasibility was defined as successful fentanyl administration by BLS-EMT. SPSS-20 was used for descriptive statistics, and independent t-tests and Mann-Whitney U tests were used to determine inter- and intra-group differences based on transport time. RESULTS: Two hundred and eighty-eight patients (288; 14 to 93 years old) with pain scores ≥7 were eligible for the study. Of the 284 (98.6%) who successfully received subcutaneous fentanyl, 35 had missing records or data, and 249 (86.5%) were included in analyses. Average pain score pre-fentanyl was 8.9 ± 1.1. Patients <70 years old received a higher dose of fentanyl than those ≥70 years old (1.4 ± 0.3 vs, 0.8 ± 0.2 mcg/kg, p < 0.05). Pain scores decreased significantly post-fentanyl administration and the proportion of patients achieving pain relief increased significantly (p < 0.05) over the course of transport to ED (15 minutes, 30 minutes, 45+ minutes). Only 1.6% of patients experienced adverse events, including hypotension (n = 2; 0.8%), nausea (n = 1; 0.4%), and Ramsay level >3 (n = 1; 0.4%). CONCLUSION: Prehospital subcutaneous fentanyl administration by BLS-EMT with the support of an OLMC center is a safe and feasible approach to pain relief in prehospital settings, and is not associated with major adverse events. Effectiveness, subsequent to subcutaneous fentanyl administration is characterized by a decrease in pain over the course of transport to ED. Further studies are needed to compare the effectiveness of SC administration by EMS with other routes of administration and other analgesics. AN - 27058453 AU - Lebon, J. AU - Fournier, F. AU - Bégin, F. AU - Hebert, D. AU - Fleet, R. AU - Foldes-Busque, G. AU - Tanguay, A. DA - Sep-Oct DO - 10.3109/10903127.2016.1162887 DP - NLM ET - 2016/04/09 IS - 5 KW - Adolescent Adult Aged Aged, 80 and over Analgesics, Opioid/*administration & dosage/adverse effects Emergency Medical Services/statistics & numerical data Female Fentanyl/*administration & dosage/adverse effects Humans Injections, Subcutaneous Male Middle Aged Pain/*drug therapy Pain Management/*methods Pain Measurement Retrospective Studies Rural Population Suburban Population Treatment Outcome Young Adult *Basic Life Support *fentanyl *pain management *prehospital *subcutaneous administration LA - eng N1 - 1545-0066 Lebon, Johann Fournier, Francis Bégin, François Hebert, Denise Fleet, Richard Foldes-Busque, Guilaume Tanguay, Alain Journal Article England Prehosp Emerg Care. 2016 Sep-Oct;20(5):648-56. doi: 10.3109/10903127.2016.1162887. Epub 2016 Apr 8. PY - 2016 SN - 1090-3127 SP - 648-56 ST - Subcutaneous Fentanyl Administration: A Novel Approach for Pain Management in a Rural and Suburban Prehospital Setting T2 - Prehosp Emerg Care TI - Subcutaneous Fentanyl Administration: A Novel Approach for Pain Management in a Rural and Suburban Prehospital Setting VL - 20 ID - 3799 ER - TY - JOUR AB - Background and objectives: Adequate pain management is a major challenge of public health. The majority of students graduating from medical schools has insufficient education and experience with patients suffering pain. Not enough is being taught regarding pain in non-verbal patients (children, critically ill in the intensive care unit, demented). Chronic pain is the most difficult to optimize and requires appropriate preparation at the level of medical school. Our aim was to evaluate attitudes, expectations and the actual knowledge of medical students at different levels of their career path regarding the assessment and treatment of acute and chronic pain. Materials and Methods: We performed an observational cross-sectional study that was based on a survey distributed among medical students of pre-clinical and post-clinical years at the Pomeranian Medical University in Szczecin, Poland. The survey included: demographic data, number of hours of formal pain teaching, actual knowledge of pain assessment, and pain treatment options in adults and children. Results: We received responses from 77/364 (21.15%) students and 79.2% of them rated the need to obtain knowledge regarding pain as very important (10/10 points). Post-clinical group declared having on average 11.51 h of acute pain teaching as compared to the 7.4 h reported by the pre-clinical group (p = 0.012). Graduating students also reported having significantly more classes regarding the treatment of chronic pain (6.08 h vs. 3.79 h, p = 0.007). The average level of comfort in the post-clinical group regarding treatment of acute pain was higher than in the pre-clinical group (6.05 vs. 4.26, p = 0.006), similarly with chronic pain treatment in adults (4.33 vs. 2.97, p = 0.021) and with pain treatment in children (3.14 vs. 1.97, p = 0.026). Conclusions: This study shows that education about pain management is a priority to medical students. Despite this, there continues to be a discrepancy between students' expectations and the actual teaching and knowledge regarding effective pain management, including the vulnerable groups: chronic pain patients, children, and critically ill people. AN - WOS:000490752800026 AU - Lechowicz, K. AU - Karolak, I. AU - Drozdzal, S. AU - Zukowski, M. AU - Szylinska, A. AU - Bialecka, M. AU - Rotter, I. AU - Kotfis, K. C7 - 533 DA - Sep DO - 10.3390/medicina55090533 IS - 9 N1 - Lechowicz, Kacper Karolak, Igor Drozdzal, Sylwester Zukowski, Maciej Szylinska, Aleksandra Bialecka, Monika Rotter, Iwona Kotfis, Katarzyna Szylinska, Aleksandra/M-7889-2014; Kotfis, Katarzyna/O-4355-2014; Lechowicz, Kacper/AAF-7330-2019; Zukowski, Maciej/A-3415-2015; Rotter, Iwona/O-6539-2014 Szylinska, Aleksandra/0000-0001-6105-5329; Kotfis, Katarzyna/0000-0001-8430-1369; Lechowicz, Kacper/0000-0002-0807-8510; Zukowski, Maciej/0000-0001-5733-0818; Bialecka, Monika/0000-0002-3137-2224; Rotter, Iwona/0000-0002-4337-6476; Drozdzal, Sylwester/0000-0002-4082-2696 1648-9144 PY - 2019 SN - 1010-660X ST - Acute and Chronic Pain Learning and Teaching in Medical School-An Observational Cross-Sectional Study Regarding Preparation and Self-Confidence of Clinical and Pre-Clinical Medical Students T2 - Medicina-Lithuania TI - Acute and Chronic Pain Learning and Teaching in Medical School-An Observational Cross-Sectional Study Regarding Preparation and Self-Confidence of Clinical and Pre-Clinical Medical Students UR - ://WOS:000490752800026 VL - 55 ID - 1886 ER - TY - JOUR AB - Pediatric migraine is a disorder that significantly interferes with the everyday life and school life of approximately 8% of children and adolescents in Korea. Recently, studies on migraine have been carried out very rapidly, many drugs have been developed, and acute-phase and preventive treatments for migraine have been evaluated. Therefore, it is necessary to understand the diagnostic criteria and degree of impairment in pediatric migraine and to become familiar with up-to-date treatment methods in children. Research into the use of botulinum toxin or calcitonin gene-related peptide antagonists to treat adult migraine headaches is progressing, and we expect these therapies to be applicable to pediatric patients soon. Many students in our country are suffering from migraines in their daily life. Therefore, we need to acquire the relevant knowledge and identify practical treatment methods for pediatric migraine in children and adolescents in order to reduce their pain. AN - WOS:000397260400004 AU - Lee, K. H. DA - Feb DO - 10.5124/jkma.2017.60.2.118 IS - 2 N1 - Lee, Kon-Hee 2093-5951 PY - 2017 SN - 1975-8456 SP - 118-125 ST - Recent updates on treatment for pediatric migraine T2 - Journal of the Korean Medical Association TI - Recent updates on treatment for pediatric migraine UR - ://WOS:000397260400004 VL - 60 ID - 2109 ER - TY - JOUR AN - WOS:000648922701230 AU - Lee, L. AU - Moylan, M. AU - Fales, J. DA - Apr N1 - Lee, Lyvinna Moylan, Maria Fales, Jessica 1532-4796 1 PY - 2021 SN - 0883-6612 SP - S513-S513 ST - WHEN HURT PEOPLE HURT PEOPLE: BULLY-VICTIM STATUS AND ITS LINKS TO HEALTH OUTCOMES IN YOUTH WITH AND WITHOUT CHRONIC PAIN T2 - Annals of Behavioral Medicine TI - WHEN HURT PEOPLE HURT PEOPLE: BULLY-VICTIM STATUS AND ITS LINKS TO HEALTH OUTCOMES IN YOUTH WITH AND WITHOUT CHRONIC PAIN UR - ://WOS:000648922701230 VL - 55 ID - 1742 ER - TY - JOUR AB - Headache is one of the most common neurological symptoms reported in childhood and adolescence, leading to high levels of school absences, learning problems, and poor psychiatric conditions. Pediatric headache has been associated with several neurological and psychiatric comorbidities; in particular, depression, anxiety disorders, sleep disorders, and epilepsy have been associated with pediatric migraine. The goal of this article is to review the comorbidities associated with pediatric headache, thereby enabling pediatric neurologists to identify shared triggers and develop synergistic management strategies that address headache and its comorbidities. AN - WOS:000397260400006 AU - Lee, Y. J. DA - Feb DO - 10.5124/jkma.2017.60.2.134 IS - 2 N1 - Lee, Yun-Jin Lee, Yun-Jin/0000-0003-4727-7018 2093-5951 PY - 2017 SN - 1975-8456 SP - 134-139 ST - Comorbidities of primary headache in children T2 - Journal of the Korean Medical Association TI - Comorbidities of primary headache in children UR - ://WOS:000397260400006 VL - 60 ID - 2111 ER - TY - JOUR AB - Background The identified preventable risk factors for primary headache in adolescents are smoking; consumption of coffee or alcoholic mixed drinks; physical inactivity; muscle pain in the head, neck, or shoulder region; and chronic stress. Objective To investigate the interrelation of headache with other health complaints and the specificity of the above-mentioned risk factors for headache in adolescents. Methods A total of 1,260 students (grades 10 and 11) filled in questionnaires on headache, dietary, and lifestyle factors. The type of headache and health complaints such as dizziness, abdominal pain, musculoskeletal pains, symptoms of possible fatigue syndrome, and psychic complaints were assessed. Results Isolated headache was found in 18% of the headache sufferers; most frequently isolated tension-type headache (78.2%). Only among adolescents with a combination of headache (mainly migraine) and other health complaints, significant associations for almost all analyzed risk factors were found. The strength of the associations with the considered risk factors was very similar in all three analyzed strata except for considerably lower odds ratios for isolated headache. Conclusion All analyzed risk factors are nonspecific for headache in adolescents because they also increase the risk for other health complaints. Interventions, therefore, should consider a holistic approach focusing not only on headache but also on a broader spectrum of health complaints. AN - WOS:000314100400007 AU - Lehmann, S. AU - Milde-Busch, A. AU - Straube, A. AU - von Kries, R. AU - Heinen, F. DA - Feb DO - 10.1055/s-0032-1333432 IS - 1 N1 - Lehmann, Steffi Milde-Busch, Astrid Straube, Andreas von Kries, Ruediger Heinen, Florian Heinen, Florian/B-6594-2015 Heinen, Florian/0000-0002-3872-6136 1439-1899 PY - 2013 SN - 0174-304X SP - 46-54 ST - How Specific Are Risk Factors for Headache in Adolescents? Results from a Cross-sectional Study in Germany T2 - Neuropediatrics TI - How Specific Are Risk Factors for Headache in Adolescents? Results from a Cross-sectional Study in Germany UR - ://WOS:000314100400007 VL - 44 ID - 2384 ER - TY - JOUR AB - BACKGROUND: The objective of this study was to measure the direct costs of treating irritable bowel syndrome (IBS) and the indirect costs in the workplace. This was accomplished through retrospective analysis of administrative claims data from a national Fortune 100 manufacturer, which includes all medical, pharmaceutical, and disability claims for the company's employees, spouses/dependents, and retirees. METHODS: Patients with IBS were identified as individuals, aged 18 to 64 years, who received a primary code for IBS or a secondary code for IBS and a primary code for constipation or abdominal pain between January 1, 1996, and December 31, 1998. Of these patients with IBS, 93.7% were matched based on age, sex, employment status, and ZIP code to a control population of beneficiaries. Direct and indirect costs for patients with IBS were compared with those of matched controls. RESULTS: The average total cost (direct plus indirect) per patient with IBS was 4527 dollars in 1998 compared with 3276 dollars for a control beneficiary (P<.001). The average physician visit costs were 524 dollars and 345 dollars for patients with IBS and controls, respectively (P<.001). The average outpatient care costs to the employer were 1258 dollars and 742 dollars for patients with IBS and controls, respectively (P<.001). Medically related work absenteeism cost the employer 901 dollars on average per employee treated for IBS compared with 528 dollars on average per employee without IBS (P<.001). CONCLUSION: Irritable bowel syndrome is a significant financial burden on the employer that arises from an increase in direct and indirect costs compared with the control group. AD - Analysis Group/Economics, Boston, MA 02199, USA. sleong@analysisgroup.com AN - 12719202 AU - Leong, S. A. AU - Barghout, V. AU - Birnbaum, H. G. AU - Thibeault, C. E. AU - Ben-Hamadi, R. AU - Frech, F. AU - Ofman, J. J. DA - Apr 28 DO - 10.1001/archinte.163.8.929 DP - NLM ET - 2003/04/30 IS - 8 KW - Absenteeism Adolescent Adult Case-Control Studies Colonic Diseases, Functional/*economics *Cost of Illness Direct Service Costs/*statistics & numerical data Drug Costs/statistics & numerical data Employer Health Costs/*statistics & numerical data Female Health Expenditures/statistics & numerical data Humans Insurance Claim Reporting Male Middle Aged Retrospective Studies Sick Leave/economics United States LA - eng N1 - Leong, Stephanie A Barghout, Victoria Birnbaum, Howard G Thibeault, Crystal E Ben-Hamadi, Rym Frech, Feride Ofman, Joshua J Comparative Study Journal Article Research Support, Non-U.S. Gov't United States Arch Intern Med. 2003 Apr 28;163(8):929-35. doi: 10.1001/archinte.163.8.929. PY - 2003 SN - 0003-9926 (Print) 0003-9926 SP - 929-35 ST - The economic consequences of irritable bowel syndrome: a US employer perspective T2 - Arch Intern Med TI - The economic consequences of irritable bowel syndrome: a US employer perspective VL - 163 ID - 3706 ER - TY - JOUR AB - The purpose of this article is to describe the narratives of adolescents about the perception of the bullying phenomenon at school, approaching the philosophical perspective of Merleau-Ponty's phenomenology with the educational field. The importance of this investigation is to value the perception of each person investigated about the bullying phenomenon and its implications for the lived world, considering its existence, its relations with itself, with the other and with the environment. It was concluded with the research that adolescents perceive bullying as a very bad problem that generates pain and suffering. Adolescents find themselves alone when they experience bullying. They explained the need to form groups of friends to help each other and, thus create a network of protection and reaction against the bullying phenomenon. AN - WOS:000556167100001 AU - Leopoldino, E. R. AU - Santos, L. A. M. AU - Caminha, I. O. C7 - e-14087 DO - 10.20952/revtee.v13i32.14087 IS - 32 N1 - Leopoldino, Elcio Rezek Menezes Santos, Luiz Anselmo Caminha, Iraquitan Oliveira Educacao, Revista Tempos e Espacos em/AAA-6734-2020; Leopoldino, Elcio Rezek/AAH-6672-2021 2358-1425 PY - 2020 SN - 1983-6597 ST - EDUCATION AND PHENOMENOLOGY: THE PERCEPTION OF ADOLESCENTS ABOUT BULLYING AT SCHOOL T2 - Revista Tempos E Espacos Educacao TI - EDUCATION AND PHENOMENOLOGY: THE PERCEPTION OF ADOLESCENTS ABOUT BULLYING AT SCHOOL UR - ://WOS:000556167100001 VL - 13 ID - 1853 ER - TY - JOUR AB - PURPOSE: Sudden visual impairment in children occurs sporadically but, when present, needs urgent attention. Optimal management strategies and timely recognition are required. Often psychogenic disorders are the cause in school-age children; however, this is a diagnosis of exclusion. Therefore, MRI plays an important role in ruling out pathology along the optic pathways or helping with the diagnosis of underlying life threatening diseases, such as hydrocephalus or intracranial mass. The purpose of this study was first to evaluate non-traumatic (tumoural and non-tumoural) causes of acute vision impairment; and, second, to assess whether conventional cerebral and orbital MR imaging is helpful for children with sudden visual impairment. PATIENTS AND METHODS: We retrospectively analysed the MRI scans and clinical findings of 95 children (47 male, 48 female; median age: 12.5 years, range: from 2 to 17 years) who presented symptoms of monocular or bilateral acute vision impairment. RESULTS: Patients with acute visual impairment were usually older than 7 years. In 36% of the patients a correlation between the MRI findings and the clinical symptoms was found. The most common causes of visual impairment were: infectious diseases (16%), migraine (12%), autoimmune diseases (11%), optic nerve neuritis with unknown aetiology (8%), neoplasms (8%), idiopathic intracranial hypertension (5%) and orthostatic hypotension (4%). Still, in 23% of the patients the cause remained unclear. CONCLUSION: Acute vision impairment is frequently caused by infectious diseases, migraine, autoimmune diseases or tumours in children. MRI is highly recommended, especially in the case of children younger than 5 years of whom clinical assessment can be difficult. AD - Institute of Neuroradiology, Hospital of Goethe University, Frankfurt am Main, Germany. Electronic address: stephanie.lescher@kgu.de. Institute of Neuroradiology, Hospital of Goethe University, Frankfurt am Main, Germany. Electronic address: valerie-w@gmx.de. Department of Paediatric Neurology, Hospital of Goethe University, Frankfurt am Main, Germany. Electronic address: Peter.Hofstetter@kgu.de. Institute of Neuroradiology, Hospital of Goethe University, Frankfurt am Main, Germany. Electronic address: Luciana.Porto@kgu.de. AN - 27025301 AU - Lescher, S. AU - Wickmann, V. AU - Hofstetter, P. AU - Porto, L. DA - Jul DO - 10.1016/j.ejpn.2016.03.001 DP - NLM ET - 2016/03/31 IS - 4 KW - Acute Disease Adolescent Brain Neoplasms/complications/*diagnostic imaging Child Child, Preschool Eye Infections/complications/diagnosis/*diagnostic imaging Female Humans Hydrocephalus/complications/*diagnostic imaging Hypotension, Orthostatic/complications/diagnosis/*diagnostic imaging Magnetic Resonance Imaging Male Migraine Disorders/complications/diagnosis/*diagnostic imaging Optic Neuritis/complications/*diagnostic imaging Pseudotumor Cerebri/complications/*diagnostic imaging Retrospective Studies Vision Disorders/*diagnostic imaging/etiology Mri Paediatric patients Vision impairment LA - eng N1 - 1532-2130 Lescher, Stephanie Wickmann, Valerie Hofstetter, Peter Porto, Luciana Journal Article England Eur J Paediatr Neurol. 2016 Jul;20(4):616-24. doi: 10.1016/j.ejpn.2016.03.001. Epub 2016 Mar 17. PY - 2016 SN - 1090-3798 SP - 616-24 ST - Paediatric patients with sudden vision impairment - An overview of MRI findings T2 - Eur J Paediatr Neurol TI - Paediatric patients with sudden vision impairment - An overview of MRI findings VL - 20 ID - 3673 ER - TY - JOUR AB - Objective. Trigeminal neuralgia is rarely caused by arteriovenous malformations of the posterior fossa. Embolization of aberrant vessels can provide symptomatic relief; however, embolization is not always technically possible, and its effects can be temporary. Embolization of the nerve's blood supply could reduce its excitability and provide pain relief. Setting. The study was set in an academic tertiary care center. Study Design. The study was designed as a report of a clinical case. Summary. The authors report the case of a 13-year-old girl with a large, unruptured posterior fossa arteriovenous malformation (AVM) presented with left-sided V2-division trigeminal neuralgia. She had undergone multiple previous embolizations of feeding vessels from the anterior inferior cerebellar artery with temporary relief of her symptoms. Embolization of the middle meningeal artery was attempted, but the vessel's tortuosity precluded safe catheterization. Instead, the artery of the foramen rotundum, which had minimal contribution 1824 to the AVM nidus, was embolized with Onyx copolymer. The patient had immediate cessation of her neuralgia, with a small area of hypesthesia above her left cheek. Complete pain relief lasted for 8 months, followed by a return of mild dysesthesia episodes not requiring intervention. Conclusion. This case may represent a new method of palliative treatment for AVM-associated trigemina I neuralgia, or potentially trigeminal neuralgia of other etiologies. Based on this case's success, a prospective study using additional provocative testing with intraarterial lidocaine is proposed. AN - WOS:000298488500014 AU - Levitt, M. R. AU - Ramanathan, D. AU - Vaidya, S. S. AU - Hallam, D. K. AU - Ghodke, B. V. DA - Dec DO - 10.1111/j.1526-4637.2011.01277.x IS - 12 N1 - Levitt, Michael R. Ramanathan, Dinesh Vaidya, Sandeep S. Hallam, Danial K. Ghodke, Basavaraj V. 1526-4637 PY - 2011 SN - 1526-2375 SP - 1824-1830 ST - Endovascular Palliation of AVM-Associated Intractable Trigeminal Neuralgia via Embolization of the Artery of the Foramen Rotundum T2 - Pain Medicine TI - Endovascular Palliation of AVM-Associated Intractable Trigeminal Neuralgia via Embolization of the Artery of the Foramen Rotundum UR - ://WOS:000298488500014 VL - 12 ID - 2465 ER - TY - JOUR AB - To determine whether the accepted principles of management of open tibia fractures apply to children, 40 consecutive open fractures of the tibial shaft in skeletally immature patients were retrospectively reviewed. Attempts were made to evaluate the functional and social impact of open tibia fractures in children. All open fractures were initially treated by rapid irrigation and debridement which was repeated every 48 hours until soft tissues stabilized. The average age was 10.1 years and average follow up was 26 months (range: 18 to 84). There were 16 grade I, 10 grade II, and 14 grade III open fractures. The grade III fractures were further subdivided into 6 grade IIIA, 7 grade IIIB, and 1 grade IIIC. The average time to union was 7.5 and 11.0 weeks in the grade I and II fractures respectively, with no infections and no delayed unions. In grade III fractures, the average time to union was 15 weeks, with 1 infection and 3 delayed unions. Bone grafting using autogenous iliac crest was performed on 2 patients. The children surveyed missed an average of 4.1 months of school and 33% had to repeat a year. Twenty-five percent of the children complained of nightmares involving the events of the accident. Chronic pain despite solid union was found in 30% of patients. Forty percent of those surveyed (7 grade III fractures) complained of a limp. The low incidence of soft tissue complications and infections in the study population supports applying in children the same basic soft tissue management principles of open fracture treatment as used in adults. While bone stabilization options are limited in children, the rate of successful union without adjunctive bone grafting is much higher than that of adults treated under similar protocols. Routine early iliac crest bone grafting is unnecessary. The prevalence of gait abnormality despite fracture union should be taken into account during the patient's rehabilitation. The extensive time missed from school and resulting scholastic setback should not be underestimated. AN - WOS:A1997XM09300002 AU - Levy, A. S. AU - Bromberg, J. AU - Wetzler, M. AU - Spoo, J. AU - Lewars, M. AU - Whitelaw, G. P. DA - Jul IS - 7 N1 - Levy, AS Bromberg, J Wetzler, M Spoo, J Lewars, M Whitelaw, GP PY - 1997 SN - 0147-7447 SP - 593-598 ST - The orthopedic and social outcome of open tibia fractures in children T2 - Orthopedics TI - The orthopedic and social outcome of open tibia fractures in children UR - ://WOS:A1997XM09300002 VL - 20 ID - 2908 ER - TY - JOUR AB - Objectives: Cognitive-behavioral (CB) interventions improve outcomes for many pediatric health conditions, but little is known about which mechanisms mediate these outcomes. The goal of this study was to identify whether changes in targeted process variables from baseline to 1 week posttreatment mediate improvement in outcomes in a randomized controlled trial of a brief CB intervention for idiopathic childhood abdominal pain. Materials and Methods: Two hundred children with persistent functional abdominal pain and their parents were randomly assigned to 1 of 2 conditions: a 3-session social learning and CB treatment (N = 100), or a 3-session educational intervention controlling for time and attention (N = 100). Outcomes were assessed at 3-, 6-, and 12-month follow-ups. The intervention focused on altering parental responses to pain and on increasing adaptive cognitions and coping strategies related to pain in both parents and children. Results: Multiple mediation analyses were applied to examine the extent to which the effects of the social learning and CB treatment condition on child gastrointestinal (GI) symptom severity and pain as reported by children and their parents were mediated by changes in targeted cognitive process variables and parents' solicitous responses to their child's pain symptoms. Reductions in parents' perceived threat regarding their child's pain mediated reductions in both parent-reported and child-reported GI symptom severity and pain. Reductions in children's catastrophic cognitions mediated reductions in child-reported GI symptom severity but no other outcomes. Reductions in parental solicitousness did not mediate outcomes. Discussion: Results suggest that reductions in reports of children's pain and GI symptoms after a social learning and CB intervention were mediated at least in part by decreasing maladaptive parent and child cognitions. AN - WOS:000345158300003 AU - Levy, R. L. AU - Langer, S. L. AU - Romano, J. M. AU - Labus, J. AU - Walker, L. S. AU - Murphy, T. B. AU - Van Tilburg, M. A. L. AU - Feld, L. D. AU - Christie, D. L. AU - Whitehead, W. E. DA - Dec DO - 10.1097/ajp.0000000000000077 IS - 12 N1 - Levy, Rona L. Langer, Shelby L. Romano, Joan M. Labus, Jennifer Walker, Lynn S. Murphy, Tasha B. Van Tilburg, Miranda A. L. Feld, Lauren D. Christie, Dennis L. Whitehead, William E. Labus, Jennifer S/M-4567-2017 Labus, Jennifer S/0000-0002-6634-2551; van tilburg, miranda/0000-0002-0504-9829 1536-5409 PY - 2014 SN - 0749-8047 SP - 1033-1043 ST - Cognitive Mediators of Treatment Outcomes in Pediatric Functional Abdominal Pain T2 - Clinical Journal of Pain TI - Cognitive Mediators of Treatment Outcomes in Pediatric Functional Abdominal Pain UR - ://WOS:000345158300003 VL - 30 ID - 2273 ER - TY - JOUR AB - Background: Among adults with functional gastrointestinal disorders, psychological distress influences who consults a physician, but little is known about predictors of consultation when the patient is a child. Objective: To determine the relative contributions of psychological symptoms of the mother, psychological symptoms of the child, severity of child abdominal pain, and family stress to consultation. Design: Observational study. Setting: Health maintenance organization. Participants: Two hundred seventy-five mothers of 334 children who had abdominal pain in the past 2 weeks, as per child self-report. Main Outcome Measures: Mothers completed questionnaires about themselves (Symptom Checklist 90 Revised) and their children (school absences, medication use, and the Child Behavior Checklist). Children completed the Pain Beliefs Questionnaire to assess perceived pain severity. Results: Thirty-nine children had been taken to the clinic for abdominal pain symptoms at least once in the past 3 months (consulters), whereas 295 were nonconsulters. Logistic regression analyses revealed that both the child's self-report of perceived pain severity (P <.001) and maternal psychological symptoms (P=.006) predicted consultation. Although children who visited physicians had significantly more psychological symptoms, this was not a significant predictor of consultation after adjusting for maternal psychological symptoms. Family stress did not predict consultation. Conclusion: The decision to take a child to the clinic for abdominal pain is best predicted by maternal psychological distress and the child's perceived pain severity. AN - WOS:000240234800015 AU - Levy, R. L. AU - Langer, S. L. AU - Walker, L. S. AU - Feld, L. D. AU - Whitehead, W. E. DA - Sep DO - 10.1001/archpedi.160.9.961 IS - 9 N1 - Levy, Rona L. Langer, Shelby L. Walker, Lynn S. Feld, Lauren D. Whitehead, William E. 1538-3628 PY - 2006 SN - 1072-4710 SP - 961-965 ST - Relationship between the decision to take a child to the clinic for abdominal pain and maternal psychological distress T2 - Archives of Pediatrics & Adolescent Medicine TI - Relationship between the decision to take a child to the clinic for abdominal pain and maternal psychological distress UR - ://WOS:000240234800015 VL - 160 ID - 2719 ER - TY - JOUR AB - Background: Studies testing the efficacy of behavioral interventions to modify psychosocial sequelae of inflammatory bowel disease in children are limited. This report presents outcomes through a 6-month follow-up from a large randomized controlled trial testing the efficacy of a cognitive behavioral intervention for children with inflammatory bowel disease and their parents. Methods: One hundred eighty-five children aged 8 to 17 years with a diagnosis of Crohn's disease or ulcerative colitis and their parents were randomized to one of two 3-session conditions: (1) a social learning and cognitive behavioral therapy condition or (2) an education support condition designed to control for time and attention. Results: There was a significant overall treatment effect for school absences due to Crohn's disease or ulcerative colitis (P < 0.05) at 6 months after treatment. There was also a significant overall effect after treatment for child-reported quality of life (P < 0.05), parent-reported increases in adaptive child coping (P < 0.001), and reductions in parents' maladaptive responses to children's symptoms (P < 0.05). Finally, exploratory analyses indicated that for children with a higher level of flares (2 or more) prebaseline, those in social learning and cognitive behavioral therapy condition experienced a greater reduction in flares after treatment. Conclusions: This trial suggests that a brief cognitive behavioral intervention for children with inflammatory bowel disease and their parents can result in improved child functioning and quality of life, and for some children may decrease disease activity. AN - WOS:000384464800019 AU - Levy, R. L. AU - van Tilburg, M. A. L. AU - Langer, S. L. AU - Romano, J. M. AU - Walker, L. S. AU - Mancl, L. A. AU - Murphy, T. B. AU - Claar, R. L. AU - Feld, S. I. AU - Christie, D. L. AU - Abdullah, B. AU - DuPen, M. M. AU - Swanson, K. S. AU - Baker, M. D. AU - Stoner, S. A. AU - Whitehead, W. E. DA - Sep DO - 10.1097/mib.0000000000000881 IS - 9 N1 - Levy, Rona L. van Tilburg, Miranda A. L. Langer, Shelby L. Romano, Joan M. Walker, Lynn S. Mancl, Lloyd A. Murphy, Tasha B. Claar, Robyn L. Feld, Shara I. Christie, Dennis L. Abdullah, Bisher DuPen, Melissa M. Swanson, Kimberly S. Baker, Melissa D. Stoner, Susan A. Whitehead, William E. van tilburg, miranda/0000-0002-0504-9829; Stoner, Susan/0000-0001-8548-219X 1536-4844 PY - 2016 SN - 1078-0998 SP - 2134-2148 ST - Effects of a Cognitive Behavioral Therapy Intervention Trial to Improve Disease Outcomes in Children with Inflammatory Bowel Disease T2 - Inflammatory Bowel Diseases TI - Effects of a Cognitive Behavioral Therapy Intervention Trial to Improve Disease Outcomes in Children with Inflammatory Bowel Disease UR - ://WOS:000384464800019 VL - 22 ID - 2148 ER - TY - JOUR AB - OBJECTIVES: Irritable bowel syndrome (IBS) runs in families. The aims of this study were (1) to exclude biased perception by a mother with irritable bowel as the explanation for increased gastrointestinal (GI) symptoms in their children, (ii) to determine whether non-GI as well as GI symptoms run in families, and (iii) to determine whether parent IBS status and solicitous responses to illness exert independent effects on children's symptom reports, medical clinic visits, and school absences. METHODS: Two hundred and eight mothers with irritable bowel and their 296 children (cases: average age 11.9 yr; 48.6% male) and 241 nonirritable bowel mothers and their 335 children (controls: 11.8 yr; 49.0% male) were interviewed. Other factors assessed were stress, mother's and child's psychological symptoms, child's perceived competence, pain coping style, age, and sex. Children were interviewed apart from their parents. RESULTS: Case children independently reported more frequent stomach aches (F(591) = 9.22; p = 0.0025) and non-GI symptoms (F(562) 21.03; p < 0.001) than control children. Case children also had more school absences (F(625) 26.53; p < 0.0001), physician visits for GI symptoms (F(602) 8.09; p = 0.005), and non-GI clinic visits (F(602) = 27.92; p <0.001) than control children. Children whose mothers made solicitous responses to illness complaints independently reported more severe stomach aches (F(590) = 11.42; p < 0.001), and they also had more school absences for stomach aches (F(625) = 5.33; p < 0.05), but solicitous behavior did not significantly impact non-GI symptom reporting, clinic visits, or school absences. Differences between cases and controls remained significant after adjusting for potential moderators. CONCLUSIONS: (i) Frequent GI complaints in children whose mothers have irritable bowel are not explained by the mother's biased perceptions; (ii) children of mothers with irritable bowel have more non-GI as well as GI symptoms, disability days, and clinical visits; (iii) and parent IBS status and solicitous responses to illness have independent effects on the child's symptom complaints. AN - WOS:000225627500026 AU - Levy, R. L. AU - Whitehead, W. E. AU - Walker, L. S. AU - Von Korff, M. AU - Feld, A. D. AU - Garner, J. D. M. AU - Christie, D. DA - Dec DO - 10.1111/j.1572-0241.2004.40478.x IS - 12 N1 - Levy, RL Whitehead, WE Walker, LS Von Korff, M Feld, AD Garner, JDM Christie, D VonKorff, Michael/0000-0001-5386-8477 PY - 2004 SN - 0002-9270 SP - 2442-2451 ST - Increased somatic complaints and health-care utilization in children: Effects of parent IBS status and parent response to gastrointestinal symptoms T2 - American Journal of Gastroenterology TI - Increased somatic complaints and health-care utilization in children: Effects of parent IBS status and parent response to gastrointestinal symptoms UR - ://WOS:000225627500026 VL - 99 ID - 2781 ER - TY - JOUR AB - Cyclic vomiting syndrome (CVS) remains a mysterious disorder despite our increasing knowledge since its classic description by Gee in 1882. Its hallmark feature of recurrent, explosive bouts of vomiting punctuating periods of normal health causes substantial medical morbidity (50% of patients require intravenous therapy), as well as significant time lost from school (20 school absences per year) and work. Limited epidemiologic data indicate that CVS may occur more commonly than previously thought, affecting as many as 1.9% of school-aged children. Besides the relentless vomiting, the child usually has pallor (87%), lethargy (91%), anorexia (74%), nausea (72%), and abdominal pain (80%). There is evidence of clinical and physiologic overlap among CVS, abdominal migraine, and migraine headaches. We propose revised criteria for abdominal migraine that include pain as the predominant and consistent symptom, lack of abnormal screening tests, and in retrospect, either subsequent development of migraines or positive response to antimigraine medication. Besides migraines, other etiologic possibilities include mitochondrial DNA mutations, ion channelopathies, excessive hypothalamic-pituitary-adrenal axis activation, and heightened autonomic reactivity. The differential diagnosis includes idiopathic CVS (88%); gastrointestinal disorders (7%), including serious surgical disorders (e.g., malrotation); and extraintestinal disorders (5%), including serious surgical (brain stem neoplasm) and metabolic disorders (e.g., fatty acid oxidation disorder). Within the idiopathic group, there may be migraine, Sato's neuroendocrine, mitochondrial, and other subgroups. Treatment includes avoidance of triggers, prophylactic medication, supportive care, abortive medication, and family support. In the future, investigation into mitochondrial DNA mutations, ion channel defects, corticotropin-releasing factor, and serotonin and tachykinin receptor physiology and pharmacology may help discover the etiology and pathogenesis of this disorder. AD - Ohio State University, USA. AN - 10959442 AU - Li, B. U. AU - Balint, J. P. DP - NLM ET - 2000/08/26 KW - Antiemetics/therapeutic use Antipsychotic Agents/therapeutic use Child Diagnosis, Differential Female Forecasting Humans Hypothalamus/physiology Intestinal Diseases/complications/pathology Male Migraine Disorders/*complications/diagnosis *Periodicity Stress, Psychological/complications/physiopathology Vomiting/epidemiology/*etiology/therapy LA - eng N1 - Li, B U Balint, J P R03-DK53028-01/DK/NIDDK NIH HHS/United States Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Review United States Adv Pediatr. 2000;47:117-60. PY - 2000 SN - 0065-3101 (Print) 0065-3101 SP - 117-60 ST - Cyclic vomiting syndrome: evolution in our understanding of a brain-gut disorder T2 - Adv Pediatr TI - Cyclic vomiting syndrome: evolution in our understanding of a brain-gut disorder VL - 47 ID - 3671 ER - TY - JOUR AB - BACKGROUND: Neuropathic pain questionnaires are efficient diagnostic tools for neuropathic pain and play an important role in neuropathic pain epidemiologic studies in China. No comparison data was available in regards to the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS), the Neuropathic Pain Questionnaire (NPQ) and ID Pain within and among the same population. OBJECTIVE: To achieve a linguistic adaptation, validation, and comparison of Chinese versions of the 3 neuropathic pain questionnaires (LANSS, NPQ and ID Pain). STUDY DESIGN: A nonrandomized, controlled, prospective, multicenter trial. SETTING: Ten pain centers in China. METHODS: Two forward translations followed by comparison and reconciliation of the translations. Comparison of the 2 backward translations with the original version was made to establish consistency and accuracy of the translations. Pilot testing and pain specialists' evaluations were also required. A total of 140 patients were enrolled in 10 centers throughout China: 70 neuropathic pain patients and 70 nociceptive pain patients. Reliability (Cronbach's alpha coefficients and Guttman split-half coefficients) and validity (sensitivity, specificity, positive and negative predictive values, receiver operating characteristic [ROC] curves and the area under the ROC curves) of the 3 questionnaires were determined. ROC curves and the area under the ROC curves of the 3 questionnaires were also compared. RESULTS: Chinese versions of LANSS, NPQ and ID Pain had a good reliability (Cronbach's alpha coefficients and Guttman split-half coefficients were greater than 0.7). Sensitivity, specificity, positive and negative predictive values of the Chinese versions of LANSS and ID Pain were considerably high ( > 80%). The area under the ROC curves of LANSS and ID Pain was significantly higher than that of NPQ (P < 0.05). There was no statistically significant difference between the area under the ROC curves of LANSS and ID Pain (P > 0.05). LIMITATION: The study was based on patients with a high school degree or above, which limited the application of the 3 neuropathic pain questionnaires to patients with lower educational levels. CONCLUSION: The Chinese versions of LANSS and ID Pain developed and validated by this study can be used as a diagnostic tool in differentiating neuropathic pain in patients whose native language is Chinese (Mandarin). AD - Department of Anesthesiology and Pain Medicine, Peking University People's Hospital of Beijing, 11 South Street Xizhimen, Xicheng District, Beijing, China AN - 22430656 AU - Li, J. AU - Feng, Y. AU - Han, J. AU - Fan, B. AU - Wu, D. AU - Zhang, D. AU - Du, D. AU - Li, H. AU - Lim, J. AU - Wang, J. AU - Jin, Y. AU - Fu, Z. DA - Mar-Apr DP - NLM ET - 2012/03/21 IS - 2 KW - Adult Aged China Female Humans *Language Linguistics/statistics & numerical data Male Middle Aged Neuralgia/*classification/*diagnosis *Pain Measurement Prospective Studies Reproducibility of Results Sensitivity and Specificity *Surveys and Questionnaires Translations LA - eng N1 - 2150-1149 Li, Jun Feng, Yi Han, Jisheng Fan, Bifa Wu, Dasheng Zhang, Daying Du, Dongping Li, Hui Lim, Jian Wang, Jiashuang Jin, Yi Fu, Zhijian Comparative Study Journal Article Multicenter Study Research Support, Non-U.S. Gov't Validation Study United States Pain Physician. 2012 Mar-Apr;15(2):179-86. PY - 2012 SN - 1533-3159 SP - 179-86 ST - Linguistic adaptation, validation and comparison of 3 routinely used neuropathic pain questionnaires T2 - Pain Physician TI - Linguistic adaptation, validation and comparison of 3 routinely used neuropathic pain questionnaires VL - 15 ID - 3537 ER - TY - JOUR AB - Background: Nocturnal awakening is the most frequent insomnia complaint in the general population. In contrast to a growing knowledge based on adults, little is known about its prevalence, correlated factors, and associations with subjective sleep perception and daytime sleepiness in children. This study was designed to assess the prevalence and the correlate factors of frequent nocturnal awakening (FNA) among Chinese school-aged children. Furthermore, the associations of FNA with subjective sleep perception and daytime sleepiness were examined. Methods: A random sample of 20,505 children aged 5.00 to 11.92 years old (boys: 49.5% vs. girls: 50.5%) participated in a cross-sectional survey, which was conducted in eight cities of China. Parent-administered questionnaires were used to collect information on children's sleep behaviors, sleep perception, and potential influential factors of FNA from six domains. Univariate and multivariate logistic regression models were performed. Results: The prevalence of FNA was 9.8% (10.0% for boys vs. 8.9% for girls) in our sampled children. The prominent FNA-related factors inclued biological health problems, such as overweight/obesity (OR = 1.70), chronic pain during night (OR = 2.47), and chronic respiratory condition (OR = 1.23), poor psychosocial condition, such as poor mental and emotional functioning (OR = 1.34), poor sleep hygiene, such as frequently doing exciting activities before bedtime (OR = 1.24) and bedtime resistance (OR = 1.42), and parents' history of insomnia (OR = 1.31). FNA was associated with subjective poor sleep quality (OR = 1.24), subjective insufficient sleep (OR = 1.21), and daytime sleepiness (OR = 1.35). Conclusion: FNA was associated with poor sleep and daytime sleepiness. Compared to sleep environment and family susceptibility, chronic health problems, poor psychosocial condition, and poor sleep hygiene had greater impact on FNA, indicating childhood FNA could be partly prevented by health promotion, by psychological intervention, and by improving sleep hygiene routine. AN - WOS:000340008700001 AU - Li, L. W. AU - Ren, J. W. AU - Shi, L. AU - Jin, X. M. AU - Yan, C. H. AU - Jiang, F. AU - Shen, X. M. AU - Li, S. H. C7 - 204 DA - Jul DO - 10.1186/1471-244x-14-204 N1 - Li, Liwen Ren, Jiwei Shi, Lei Jin, Xinming Yan, Chonghuai Jiang, Fan Shen, Xiaoming Li, Shenghui Jiang, Fan/0000-0003-0634-101X PY - 2014 SN - 1471-244X ST - Frequent nocturnal awakening in children: prevalence, risk factors, and associations with subjective sleep perception and daytime sleepiness T2 - Bmc Psychiatry TI - Frequent nocturnal awakening in children: prevalence, risk factors, and associations with subjective sleep perception and daytime sleepiness UR - ://WOS:000340008700001 VL - 14 ID - 2297 ER - TY - JOUR AB - Objective. Earlier studies have provided evidence of genetic inheritance of headache, especially migraine, but no familial occurrence has been found regarding temporomandibular disorders (TMD). In adults, headache and TMD have been found to be associated with each other, but studies on children are few. The aim of the present study was to test the hypothesis that there is no association between signs of TMD in 13-year-old headache children and their mothers. Material and methods. The study population was a nested case- control study of the population-based Finnish Family Competence Study originally consisting of over 1000 families. A structured questionnaire was sent to the families of 6-year-old children. A clinical examination was performed in 96 children with headache and 96 pairwise controls. At the age of 13 years, 75 of these same 96 children with headache and 79 of 96 headache-free controls participated in pediatric and stomatognathic examinations. Moreover, the mothers (n = 154) filled in a structured headache questionnaire and participated in the stomatognathic examination. Results. No association between mother's and child's TMD signs was found. There was a significant association between signs of TMD and both migraine and tension- type headache in children. In mothers, the association was significant only between migraine and TMD signs. Conclusions. Familial occurrence of signs of TMD cannot be found in headache children and their mothers. AN - WOS:000246742900002 AU - Liljestrom, M. R. AU - Aromaa, M. AU - Le Bell, Y. AU - Jamsa, T. AU - Helenius, H. AU - Virtanen, R. AU - Anttila, P. AU - Metsahonkala, L. AU - Rautava, P. AU - Alanen, P. AU - Sillanpaa, M. DO - 10.1080/00016350601106165 IS - 3 N1 - Liljestrom, Marjo-Ritta Aromaa, Minna Le Bell, Yrsa Jamsa, Tapio Helenius, Hans Virtanen, Ruut Anttila, Pirjo Metsahonkala, Liisa Rautava, Paivi Alanen, Pentti Sillanpaa, Matti Sillanpaa, Matti L/G-4708-2015 Sillanpaa, Matti L/0000-0003-4190-3698; Sillanpaa, Matti/0000-0002-1521-3602 PY - 2007 SN - 0001-6357 SP - 134-140 ST - Familial occurrence of signs of temporomandibular disorders in headache children and their mothers T2 - Acta Odontologica Scandinavica TI - Familial occurrence of signs of temporomandibular disorders in headache children and their mothers UR - ://WOS:000246742900002 VL - 65 ID - 2705 ER - TY - JOUR AB - BACKGROUND: The study aimed to establish the prevalence of heavy drinking, evaluate correlations between heavy drinking and socio-demographic factors, physical and psychiatric conditions, and assess the impact of heavy drinking on quality of life and days of work-loss. METHODS: Data from a nationally-representative cross-sectional sample were used. The sample comprised 6616 community-dwelling Singaporeans & Singapore Permanent Residents. The main instruments used were the World Mental Health Composite International Diagnostic Interview and EuroQol 5D. Heavy drinking was defined as consumption of 4 or more drinks, or 5 or more drinks in a day in women and men respectively. RESULTS: 12.6% of all adult Singapore residents reported heavy drinking in the last 12 months, and 15.9% reported lifetime heavy-drinking. Strong gender, ethnic, age and income differences were seen. Heavy drinking was positively associated with major depression, the presence of any mood disorder, and with chronic pain. It was also strongly associated with alcohol dependence, alcohol abuse, and nicotine dependence. Heavy-drinkers reported lower quality of life compared to non-heavy drinkers, measured using the EuroQol 5D Visual Analogue Scale. CONCLUSIONS: Singapore has a relatively high prevalence of 12-month heavy drinking of 12.6%, and lifetime heavy drinking of 15.9%. Heavy drinking was positively associated with both physical and mental health conditions, and with declines in quality of life. Continued monitoring of heavy drinking behavior and sustained efforts to mitigate the risks associated with heavy drinking is needed. AD - Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, MD3, 16 Medical Drive, S(117597), Singapore, Singapore. ephlwy@nus.edu.sg. AN - 24499269 AU - Lim, W. Y. AU - Subramaniam, M. AU - Abdin, E. AU - He, V. Y. AU - Vaingankar, J. AU - Chong, S. A. C2 - PMC4028979 DA - Oct 21 DO - 10.1186/1471-2458-13-992 DP - NLM ET - 2014/02/07 KW - Absenteeism Adolescent Adult Age Distribution Aged Binge Drinking/*epidemiology Comorbidity Cross-Sectional Studies Female Humans Male Middle Aged Prevalence Quality of Life Risk Factors Sex Distribution Singapore/epidemiology Socioeconomic Factors Time Factors Young Adult LA - eng N1 - 1471-2458 Lim, Wei-Yen Subramaniam, Mythily Abdin, Edimansyah He, Vincent Yaofeng Vaingankar, Janhavi Chong, Siow Ann Journal Article Research Support, Non-U.S. Gov't BMC Public Health. 2013 Oct 21;13:992. doi: 10.1186/1471-2458-13-992. PY - 2013 SN - 1471-2458 SP - 992 ST - Lifetime and twelve-month prevalence of heavy-drinking in Singapore: results from a representative cross-sectional study T2 - BMC Public Health TI - Lifetime and twelve-month prevalence of heavy-drinking in Singapore: results from a representative cross-sectional study VL - 13 ID - 3776 ER - TY - JOUR AB - OBJECTIVE: To describe the prevalence of headache and its interference in the activities of daily living (ADL) in female adolescent students. METHODS: This descriptive cross-sectional study enrolled 228 female adolescents from a public school in the city of Petrolina, Pernambuco, Northeast Brazil, aged ten to 19 years. A self-administered structured questionnaire about socio-demographic characteristics, occurrence of headache and its characteristics was employed. Headaches were classified according to the International Headache Society criteria. The chi-square test was used to verify possible associations, being significant p<0.05. RESULTS: After the exclusion of 24 questionnaires that did not met the inclusion criteria, 204 questionnaires were analyzed. The mean age of the adolescents was 14.0±1.4 years. The prevalence of headache was 87.7%. Of the adolescents with headache, 0.5% presented migraine without pure menstrual aura; 6.7%, migraine without aura related to menstruation; 1.6%, non-menstrual migraine without aura; 11.7%, tension-type headache and 79.3%, other headaches. Significant associations were found between pain intensity and the following variables: absenteeism (p=0.001); interference in ADL (p<0.001); medication use (p<0.001); age (p=0.045) and seek for medical care (p<0.022). CONCLUSIONS: The prevalence of headache in female adolescents observed in this study was high, with a negative impact in ADL and school attendance. Publisher: Abstract available from the publisher. spa AD - UPE, Petrolina, PE, Brasil. AN - 25119759 AU - Lima, A. S. AU - de Araújo, R. C. AU - Gomes, M. R. AU - de Almeida, L. R. AU - de Souza, G. F. AU - Cunha, S. B. AU - Pitangui, A. C. C2 - PMC4183010 DA - Jun DO - 10.1590/0103-0582201432212113 DP - NLM ET - 2014/08/15 IS - 2 KW - *Activities of Daily Living Adolescent Cross-Sectional Studies Female Headache/*epidemiology Humans Prevalence Students LA - eng por N1 - 1984-0462 Lima, Alaine Souza de Araújo, Rodrigo Cappato Gomes, Mayra Ruana de A de Almeida, Ludmila Remígio de Souza, Gabriely Feitosa F Cunha, Samara Barreto Pitangui, Ana Carolina R Journal Article Research Support, Non-U.S. Gov't Rev Paul Pediatr. 2014 Jun;32(2):256-61. doi: 10.1590/0103-0582201432212113. PY - 2014 SN - 0103-0582 (Print) 0103-0582 SP - 256-61 ST - Prevalence of headache and its interference in the activities of daily living in female adolescent students T2 - Rev Paul Pediatr TI - Prevalence of headache and its interference in the activities of daily living in female adolescent students VL - 32 ID - 3688 ER - TY - JOUR AB - STUDY DESIGN: A prevalence survey of 101 randomly selected elementary schools in the Israel Central District. OBJECTIVES: To identify and describe risk factors for low back pain that exist in the elementary school environment. SUMMARY OF BACKGROUND DATA: Recent surveys report a high prevalence of low back pain in children and adolescents that increases with age, with a correlation between low back pain in adolescence and that experienced in adulthood. Environmental risk factors have been associated with the development of low back pain in children. Because of the significant amount of time children spend in their school environment, risk factors need to be identified in this environment. METHODS: A questionnaire, completed by school nurses, measured risk factors among 10,000 children in elementary schools in Israel. These included backpack and student weight, the availability of storage facilities, the appropriateness of chair and desk height to student height, seating arrangements during frontal lessons, and physical activity at recess. RESULTS: Between 30% and 54% of students carried >15% of their body weight. Nearly 15% of the first graders and 20% of sixth graders had inappropriate chairs. In 74% of the classes, students sat with their side facing the teacher and in 35% students sat with their backs. In 6% of schools, no physical activity is offered at recess. CONCLUSIONS: Shortcomings were found in all areas investigated. There is an urgent need for health promotion programs to increase awareness and reduce risks in the school environment. AU - Limon, Susan AU - Valinsky, Liora J. AU - Ben-Shalom, Yael DA - 2004/03/15/ DO - 10.1097/01.brs.0000116695.09697.22 DP - PubMed IS - 6 J2 - Spine (Phila Pa 1976) KW - Body Weight Child Ergonomics Female Health Promotion Health Surveys Humans Interior Design and Furnishings Israel Low Back Pain Male Motor Activity Posture Prevalence Risk Factors Schools Students Surveys and Questionnaires Weight-Bearing LA - eng PY - 2004 SN - 1528-1159 SP - 697-702 ST - Children at risk T2 - Spine TI - Children at risk: risk factors for low back pain in the elementary school environment UR - http://www.ncbi.nlm.nih.gov/pubmed/15014281 VL - 29 ID - 124 ER - TY - JOUR AB - Background: Sport-related concussion is a major concern for young athletes because a growing number of children participate in sport-related activities. Postconcussive symptoms can lead to physical, academic, and social impairment. There is no definitive treatment for sport-related postconcussive symptoms, and most available pharmacologic therapies have potential side-effects. Cases: The aim of this case report is to describe the use of acupuncture in the management of sport-related postconcussive symptoms in 3 pediatric patients. All 3 patients presented with chronic postconcussive symptoms that did not improve with conventional treatments alone. A retrospective chart review was performed from 2012 to 2015 on the 3 patients who received acupuncture in a tertiary pediatric pain clinic for postconcussive symptoms. Demographics and results from the Numerical Rating Scale, a postconcussive symptoms questionnaire, and the Brief Pain Inventory were included in the review. Results: All 3 patients experienced satisfactory symptomatic reduction following acupuncture treatment. Conclusions: Acupuncture with conventional medication appeared to reduce the postconcussive symptoms in the 3 patients. AN - WOS:000387571300008 AU - Lin, K. AU - Tung, C. DA - Aug DO - 10.1089/acu.2016.1181 IS - 4 N1 - Lin, Katerina Tung, Cynthia 1933-6594 PY - 2016 SN - 1933-6586 SP - 217-222 ST - Acupuncture for Recovery from Pediatric Sport-Related Concussion T2 - Medical Acupuncture TI - Acupuncture for Recovery from Pediatric Sport-Related Concussion UR - ://WOS:000387571300008 VL - 28 ID - 2150 ER - TY - JOUR AB - The authors have earlier reported a 1-year prevalence of 13.2 +/- 1.9% for migraine in Sweden. This is a subsequent extensive postal survey of the burden of disease and attitudes among migraineurs in a sample (n = 423, 23% men and 77% women, aged 18-74 years) randomly recruited from all main regions of the country, representative of adults in the general Swedish population with self-considered migraine. Results are presented only from participants who after analysis of symptoms were found to fulfil the International Headache Society's migraine criteria. In order to assess headache duration open-mindedly, the strict time criterion 4-72 h was deliberately disregarded as an inclusion criterion. Individuals who did not consider themselves to have migraine were excluded. Less than half of the group (45%) had received a diagnosis of migraine from a physician. Accordingly, a large number of individuals that would not have come to attention in a clinic-based study have been included. The mean attack frequency was 1.3 per month, and the number of attacks per year in Swedish adults is approximately 10 million. A minority (27%) of sufferers have a majority (68%) of all attacks. The mean attack duration was 19 h. A considerable number of individuals reported attacks < 4 h (15.8%) or > 72 h (6.4%). Less than half of the individuals recovered completely between the attacks. Despite this, only every fourth (27%) participant was currently consulting a physician (6% regularly; 21% occasionally). Most of the migraineurs reported absence from school or work, a negative influence of migraine on the most important aspects of life, and an interest in testing other treatments for migraine during the last year. Of those (n = 231) migraineurs who had consulted a physician, about 60% were satisfied with information given or treatment offered. This implies, however, that there is still room for improvement in the management of migraine in Sweden. AD - Gothenburg Migraine Clinic, Gothenburg, Sweden. mattias.linde@neuro.gu.se AN - 15154855 AU - Linde, M. AU - Dahlöf, C. DA - Jun DO - 10.1111/j.1468-2982.2004.00703.x DP - NLM ET - 2004/05/25 IS - 6 KW - Adolescent Adult Aged *Attitude to Health Chi-Square Distribution *Cost of Illness Female Humans Male Middle Aged Migraine Disorders/*epidemiology/*psychology Sweden/epidemiology LA - eng N1 - Linde, M Dahlöf, C Comparative Study Journal Article Research Support, Non-U.S. Gov't England Cephalalgia. 2004 Jun;24(6):455-65. doi: 10.1111/j.1468-2982.2004.00703.x. PY - 2004 SN - 0333-1024 (Print) 0333-1024 SP - 455-65 ST - Attitudes and burden of disease among self-considered migraineurs--a nation-wide population-based survey in Sweden T2 - Cephalalgia TI - Attitudes and burden of disease among self-considered migraineurs--a nation-wide population-based survey in Sweden VL - 24 ID - 3679 ER - TY - JOUR AB - BACKGROUND AND PURPOSE: Headache disorders are very common, but their monetary costs in Europe are unknown. We performed the first comprehensive estimation of how economic resources are lost to headache in Europe. METHODS:   From November 2008 to August 2009, a cross-sectional survey was conducted in eight countries representing 55% of the adult EU population. Participation rates varied between 11% and 59%. In total, 8412 questionnaires contributed to this analysis. Using bottom-up methodology, we estimated direct (medications, outpatient health care, hospitalization and investigations) and indirect (work absenteeism and reduced productivity at work) annual per-person costs. Prevalence data, simultaneously collected and, for migraine, also derived from a systematic review, were used to impute national costs. RESULTS:   Mean per-person annual costs were €1222 for migraine (95% CI 1055-1389; indirect costs 93%), €303 for tension-type headache (TTH, 95% CI 230-376; indirect costs 92%), €3561 for medication-overuse headache (MOH, 95% CI 2487-4635; indirect costs 92%), and €253 for other headaches (95% CI 99-407; indirect costs 82%). In the EU, the total annual cost of headache amongst adults aged 18-65 years was calculated, according to our prevalence estimates, at €173 billion, apportioned to migraine (€111 billion; 64%), TTH (€21 billion; 12%), MOH (€37 billion; 21%) and other headaches (€3 billion; 2%). Using the 15% systematic review prevalence of migraine, calculated costs were somewhat lower (migraine €50 billion, all headache €112 billion annually). CONCLUSIONS:   Headache disorders are prominent health-related drivers of immense economic losses for the EU. This has immediate implications for healthcare policy. Health care for headache can be both improved and cost saving. AD - Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway. mattias.linde@ntnu.no AN - 22136117 AU - Linde, M. AU - Gustavsson, A. AU - Stovner, L. J. AU - Steiner, T. J. AU - Barré, J. AU - Katsarava, Z. AU - Lainez, J. M. AU - Lampl, C. AU - Lantéri-Minet, M. AU - Rastenyte, D. AU - Ruiz de la Torre, E. AU - Tassorelli, C. AU - Andrée, C. DA - May DO - 10.1111/j.1468-1331.2011.03612.x DP - NLM ET - 2011/12/06 IS - 5 KW - Adolescent Adult Aged *Cost of Illness Costs and Cost Analysis Cross-Sectional Studies Europe/epidemiology Female Headache Disorders/diagnosis/*economics/epidemiology/therapy Health Care Costs/*statistics & numerical data Health Surveys Humans Male Middle Aged Prevalence Young Adult LA - eng N1 - 1468-1331 Linde, M Gustavsson, A Stovner, L J Steiner, T J Barré, J Katsarava, Z Lainez, J M Lampl, C Lantéri-Minet, M Rastenyte, D Ruiz de la Torre, E Tassorelli, C Andrée, C Journal Article England Eur J Neurol. 2012 May;19(5):703-11. doi: 10.1111/j.1468-1331.2011.03612.x. Epub 2011 Dec 5. PY - 2012 SN - 1351-5101 SP - 703-11 ST - The cost of headache disorders in Europe: the Eurolight project T2 - Eur J Neurol TI - The cost of headache disorders in Europe: the Eurolight project VL - 19 ID - 3593 ER - TY - JOUR AB - In a consecutive series of 56 District Health patients with low back pain, 24 had special training and instructions in a Back School, while the 32 in a control group--even if seen regularly, did not get the same intense attention. The two groups were found to have the same characteristics. No significant differences could be demonstrated either concerning the initial duration of symptoms and sick leave or the number of recurrences and their duration during the observation year. The interpretation of this lack of positive effect is, that in this comparatively more heterogenous population the actual procedure has less influence. However, there were more patients with periods of sick-leave for different other reasons in the control group. Not surprisingly the treated group of patients were also more satisfied. We therefore conclude, that the initial treatment could be limited to advice about back care, preferably a few days bed-rest, with concrete advice about the back and prescriptions for analgesics when needed. AN - 6238404 AU - Lindequist, S. AU - Lundberg, B. AU - Wikmark, R. AU - Bergstad, B. AU - Lööf, G. AU - Ottermark, A. C. DP - NLM ET - 1984/01/01 IS - 3 KW - Absenteeism Adolescent Adult Back Pain/*rehabilitation Female Humans Male Middle Aged *Patient Education as Topic *Physical Therapy Modalities Prospective Studies Random Allocation Recurrence LA - eng N1 - Lindequist, S Lundberg, B Wikmark, R Bergstad, B Lööf, G Ottermark, A C Journal Article Sweden Scand J Rehabil Med. 1984;16(3):113-6. PY - 1984 SN - 0036-5505 (Print) 0036-5505 SP - 113-6 ST - Information and regime at low back pain T2 - Scand J Rehabil Med TI - Information and regime at low back pain VL - 16 ID - 3447 ER - TY - JOUR AB - Measures of perceived stress have been criticized for theoretical inconsistency. However, the validated pressure activation stress scale has been suggested as a theoretically sound alternative. But it is unclear how pressure and activation stress relate to objective and subjective measures including commonly used aggregate cortisol measures and health complaints respectively. Specifically, this study aimed at investigating how pressure and activation stress were related to aggregate salivary cortisol measures and recurrent pain in mid-adolescent girls and boys. Mid-adolescents (119 girls and 56 boys) provided self-reports in questionnaires on activation and pressure stress and recurrent pain (headache, stomach ache, neck/shoulder and back pain). Additionally, adolescents sampled saliva during an ordinary school day: (1) immediately at awakening; (2) 30 minutes after waking up; (3) 60 minutes after waking up, and (4) at 8 p.m. These samples were analyzed for cortisol. Hierarchical regressions showed no statistically significant associations between activation and pressure stress and cortisol, neither for girls nor for boys. However, activation and pressure stress were significantly associated with recurrent pain but only for girls. The findings may relate to subjective and objective measures reflecting distinct aspects of stress-related functioning. However, the study participants included mid-adolescents whose bodily systems are flexible and still relatively unaffected by the strain of their daily stress perceptions. To conclude, the non-significant relationships between activation and pressure stress and commonly used aggregate measures of cortisol adds to the understanding of how perceived stress may relate to physiological functioning in the daily life of adolescents when using such aggregate measures. AD - Stockholm University, Stockholm, Sweden. Stockholm University/Karolinska Institutet, Stockholm, Sweden. AN - 28054380 AU - Lindfors, P. AU - Folkesson Hellstadius, L. AU - Östberg, V. DA - Feb DO - 10.1111/sjop.12347 DP - NLM ET - 2017/01/06 IS - 1 KW - Adolescent *Diagnostic Self Evaluation Female Health Knowledge, Attitudes, Practice Humans Hydrocortisone/*metabolism Male Pain/complications/metabolism/*psychology Recurrence Saliva/chemistry *Stress, Psychological/etiology *Activation *Perceived stress *aggregate salivary cortisol measures in mid-adolescent girls and boys *cortisol *mid-adolescence *pressure *recurrent pain LA - eng N1 - 1467-9450 Lindfors, Petra Folkesson Hellstadius, Lisa Östberg, Viveca Journal Article England Scand J Psychol. 2017 Feb;58(1):36-42. doi: 10.1111/sjop.12347. PY - 2017 SN - 0036-5564 SP - 36-42 ST - Perceived stress, recurrent pain, and aggregate salivary cortisol measures in mid-adolescent girls and boys T2 - Scand J Psychol TI - Perceived stress, recurrent pain, and aggregate salivary cortisol measures in mid-adolescent girls and boys VL - 58 ID - 3105 ER - TY - JOUR AB - BACKGROUND AND AIMS: Pulsed radiofrequency is a non-neurodestructive invasive pain treatment which, in contrast to conventional continuous radiofrequency treatment, does not entail nerve tissue destruction. The aim of this study was to retrospectively analyse the short-term benefits of a broad use of pulsed radiofrequency in clinical practice. METHODS: The medical records of all patients treated with pulsed radiofrequency, or who received a diagnostic test block with a local anaesthetic in view of such a treatment, were retrospectively analysed. The patients had been referred to a tertiary pain centre in Sweden. The treatment effect one month after pulsed radiofrequency was retrospectively graded as follows, based on the wordings of the medical records: major improvement; minor improvement; no change; or worsened. RESULTS: A total of 238 patients received 587 interventions from 2009 to 2014. Chronic low back pain (CLBP) was by far the most common treatment indication (57% of patients), followed by CLBP with sciatica (9%). The age at first pulsed radiofrequency was 55 (15-94) years (mean, range), and 65% were female. Thirty-six patients (15%) underwent only a diagnostic test block using a local anaesthetic, i.e., the test block did not lead to treatment with pulsed radiofrequency. A total of 445 pulsed radiofrequency interventions were performed on 202 patients. Dichotomizing data into responders (i.e., minor or major improvement) and non-responders (i.e., worsened or no change), we found that, out of 63 responders to a median branch diagnostic test block (either at the cervical or lumbar level), 33 were responders to the first following median branch pulsed radiofrequency. Hence the positive predictive value of a median branch test block was 52%. In 127 patients, the lumbar level was targeted for median branch pulsed radiofrequency because of clinically suspected lumbar facetogenic pain. Looking at the first treatment, 30% experienced major improvement after 1 month, 16% minor improvement, 36% no change, 5% a worsened situation, and the effect was not assessable in 13% of patients. Lone dorsal root ganglion L2-treatment for suspected discogenic lumbar pain was done on 39 patients and, after one month, the effect was not assessable in 17% of patients, 14% had major improvement, 14% minor improvement, and 55% had no change. In 40 patients, a dorsal root ganglion or a peripheral nerve was targeted because of a non-axial chronic pain condition. There was a plethora of indications, but the most common was by far related to some form of neuropathic pain (52% of interventions, mainly because of neuralgia), followed by chronic nociceptive shoulder pain (8% of interventions). CONCLUSIONS: This study shows that, after one month, the effect size of a broad and indiscriminate clinical use of pulsed radiofrequency is rather small. IMPLICATIONS: The clinical effectiveness of pulsed radiofrequency has to be investigated further in carefully selected and more homogenous patient groups, in order to define effective treatment niches for this nondestructive invasive treatment method. AD - Pain and Rehabilitation Centre, and Department of Medical and Health Sciences, Linköping University, Linköping, Sweden. Pain and Rehabilitation Centre, and Department of Medical and Health Sciences, Linköping University, Linköping, Sweden. Electronic address: emmanuel.backryd@regionostergotland.se. AN - 28850497 AU - Lindquist, J. AU - Bäckryd, E. DA - Jul DO - 10.1016/j.sjpain.2016.04.008 DP - NLM ET - 2017/08/30 KW - Adolescent Adult Aged Aged, 80 and over Female Humans Male Middle Aged Neoplasms Pain Clinics *Pain Management *Pulsed Radiofrequency Treatment Retrospective Studies Sweden Young Adult *Chronic *Dorsal root ganglion *Medial branch *Pain *Pulsed *Radiofrequency LA - eng N1 - 1877-8879 Lindquist, Jan Bäckryd, Emmanuel Journal Article Germany Scand J Pain. 2016 Jul;12:68-73. doi: 10.1016/j.sjpain.2016.04.008. Epub 2016 May 10. PY - 2016 SN - 1877-8860 SP - 68-73 ST - Pulsed radiofrequency in clinical practice - A retrospective analysis of 238 patients with chronic non-cancer pain treated at an academic tertiary pain centre T2 - Scand J Pain TI - Pulsed radiofrequency in clinical practice - A retrospective analysis of 238 patients with chronic non-cancer pain treated at an academic tertiary pain centre VL - 12 ID - 3356 ER - TY - JOUR AB - Priority setting for healthcare research is as important as conducting the research itself because rigorous and systematic processes of priority setting can make an important contribution to the quality of research. This project aimed to prioritise clinical therapeutic uncertainties in paediatric pain and palliative care in order to encourage and inform the future research agenda and raise the profile of paediatric pain and palliative care in the United Kingdom. Clinical therapeutic uncertainties were identified and transformed into patient, intervention, comparison and outcome (PICO) format and prioritised using a modified Nominal Group Technique. Members of the Clinical Studies Group in Pain and Palliative Care within National Institute for Health Research (NIHR) Clinical Research Network (CRN)-Children took part in the prioritisation exercise. There were 11 clinically active professionals spanning across a wide range of paediatric disciplines and one parent representative. The top three research priorities related to establishing the safety and efficacy of (1) gabapentin in the management of chronic pain with neuropathic characteristics, (2) intravenous non-steroidal anti-inflammatory drugs in the management of post-operative pain in pre-schoolers and (3) different opioid formulations in the management of acute pain in children while at home. Questions about the long-term effect of psychological interventions in the management of chronic pain and various pharmacological interventions to improve pain and symptom management in palliative care were among the 'top 10' priorities. The results of prioritisation were included in the UK Database of Uncertainties about the Effects of Treatments (DUETS) database. Increased awareness of priorities and priority-setting processes should encourage clinicians and other stakeholders to engage in such exercises in the future. AD - Department of Psychology, University of Southampton, Southampton, UK; Department of Paediatric Psychology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK. The Royal Marsden Hospital, Sutton, UK; Shooting Star Chase Children's Hospice, Guildford, UK. Department of Anaesthesia and Pain Medicine, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK; UCL Institute of Child Health, London, UK. AN - 28386399 AU - Liossi, C. AU - Anderson, A. K. AU - Howard, R. F. C2 - PMC5370623 DA - Feb DO - 10.1177/2049463716668906 DP - NLM ET - 2017/04/08 IS - 1 KW - Research priorities paediatric pain paediatric palliative care of interest with respect to the research, authorship and/or publication of this article. LA - eng N1 - 2049-4645 Liossi, Christina Anderson, Anna-Karenia Howard, Richard F NIHR CRN-C CSG in Pain and Palliative Care Journal Article Br J Pain. 2017 Feb;11(1):9-15. doi: 10.1177/2049463716668906. Epub 2016 Sep 16. PY - 2017 SN - 2049-4637 (Print) 2049-4637 SP - 9-15 ST - Development of research priorities in paediatric pain and palliative care T2 - Br J Pain TI - Development of research priorities in paediatric pain and palliative care VL - 11 ID - 4197 ER - TY - JOUR AB - Introduction Chronic musculoskeletal pain is a complex medical condition that can significantly impact quality of life. Patients with chronic pain demonstrate attentional biases towards pain-related information. The therapeutic benefits of modifying attentional biases by implicitly training attention away from pain-related information towards neutral information have been supported in a small number of published studies. Limited research however has explored the efficacy of modifying pain-related biases via the internet. This protocol describes a randomised, double-blind, internet-delivered attentional bias modification intervention, aimed to evaluate the efficacy of the intervention on reducing pain interference. Secondary outcomes are pain intensity, state and trait anxiety, depression, pain-related fear, and sleep impairment. This study will also explore the effects of training intensity on these outcomes, along with participants' perceptions about the therapy. Methods and analysis The study is a double-blind, randomised controlled trial with four arms exploring the efficacy of online attentional bias modification training versus placebo training theorised to offer no specific therapeutic benefit. Participants with chronic musculoskeletal pain will be randomised to one of four groups: (1) 10-session attentional modification group; (2) 10-session placebo training group; (3) 18-session attentional modification group; or (4) 18-session placebo training group. In the attentional modification groups, the probe-classification version of the visual-probe task will be used to implicitly train attention away from threatening information towards neutral information. Following the intervention, participants will complete a short interview exploring their perceptions about the online training. In addition, a subgroup analysis for participants aged 16-24 and 25-60 will be undertaken. Ethics and dissemination This study has been approved by the University of Southampton Research Ethics Committee. Results will be published in peer-reviewed journals, academic conferences, and in lay reports for pain charities and patient support groups. AN - WOS:000527786700021 AU - Liossi, C. AU - Georgallis, T. AU - Zhang, J. AU - Hamilton, F. AU - White, P. AU - Schoth, D. E. C7 - e030607 DA - Feb DO - 10.1136/bmjopen-2019-030607 IS - 2 N1 - Liossi, Christina Georgallis, Tsampikos Zhang, Jin Hamilton, Fiona White, Paul Schoth, Daniel Eric PY - 2020 SN - 2044-6055 ST - Internet-delivered attentional bias modification training (iABMT) for the management of chronic musculoskeletal pain: a protocol for a randomised controlled trial T2 - Bmj Open TI - Internet-delivered attentional bias modification training (iABMT) for the management of chronic musculoskeletal pain: a protocol for a randomised controlled trial UR - ://WOS:000527786700021 VL - 10 ID - 1842 ER - TY - JOUR AB - Purpose: Recent research has suggested that autism spectrum disorder (ASD) and attention-deficit hyperactivity disorder (ADHD) may be comorbid to pediatric chronic pain, but the empirical support is yet scarce. Therefore, the current study aimed to investigate the occurrence of traits and symptoms consistent with clinically significant ASD and ADHD in a group of children and adolescents with chronic debilitating pain and examine potential differences in pain and demographic variables between children with and without clinically significant traits and symptoms of ASD and ADHD. Patients and methods: This cross-sectional study included 146 parent-child dyads (102 girls, 111 mothers, children 8-17 years) consecutively referred to a tertiary pain clinic. Parents completed the Social Responsiveness Scale to assess autistic traits, and Conners-3 to measure symptoms of ADHD in their children. Children completed the Liibeck Pain Questionnaire to evaluate experienced pain. Results: Among children, 20 (13.7%) received scores consistent with clinically significant ASD and 29 (19.9%) received scores consistent with clinically significant ADHD, with a combined prevalence of clinically significant ASD/ADHD traits and symptoms of 26% of the total sample. Only 4.8% of children were previously diagnosed with either disorder. Among children with clinically significant ASD traits, girls were more prevalent, parents reported lower health, and the pain was more likely triggered by being in school. Among children with clinically significant ADHD symptoms, there were no gender differences and pain was more likely triggered by the family situation and new situations. No differences regarding pain intensity, duration, or frequency were found between children with and without clinically significant ASD traits or ADHD symptoms. Conclusion: Children with debilitating chronic pain, particularly girls, may present with an elevated risk of having a comorbid, possibly high-functioning, neurodevelopmental disorder. Results suggest that clinical assessment of pediatric chronic pain should include screening for neurodevelopmental disorders. AN - WOS:000449450600002 AU - Lipsker, C. W. AU - Bolte, S. AU - Hirvikoski, T. AU - Lekander, M. AU - Holmstrom, L. AU - Wicksell, R. K. DO - 10.2147/jpr.S177534 N1 - Lipsker, Camilla Wiwe Bolte, Sven Hirvikoski, Tatja Lekander, Mats Holmstrom, Linda Wicksell, Rikard K. Romanova, Raisa/O-5724-2018; Holmstrom, Linda/Y-8195-2019; Bolte, Sven/AAH-8675-2019 Bolte, Sven/0000-0002-4579-4970; Hirvikoski, Tatja/0000-0003-1824-3003 PY - 2018 SN - 1178-7090 SP - 2827-2836 ST - Prevalence of autism traits and attention-deficit hyperactivity disorder symptoms in a clinical sample of children and adolescents with chronic pain T2 - Journal of Pain Research TI - Prevalence of autism traits and attention-deficit hyperactivity disorder symptoms in a clinical sample of children and adolescents with chronic pain UR - ://WOS:000449450600002 VL - 11 ID - 2047 ER - TY - JOUR AB - This article reviews the substantial impact of migraine on individual headache sufferers and on society. While the individual impact of migraine is determined by pain and role dysfunction, the societal impact is primarily determined by work loss and disability in the work place and at home. Epidemiologic studies demonstrate that migraine is very common, substantially under diagnosed and often inadequately treated. Improving health care delivery to persons with migraine could substantially reduce the individual and societal impact of the illness. Migraine ranges in severity, with mild headache and no disability on one extreme and excruciating pain and complete disability on the other. Because of this spectrum of severity, diagnosis alone does not provide enough information to permit the selection of optimal therapy. A headache grading system might help headache sufferers and clinicians match the therapy not only to the diagnosis but to the overall severity of illness; such a system provides the best hope for cost effective health care interventions. AD - Department of Neurology, Epidemiology and Social Medicìne, Albert Einstein College of Medicine, Montefiore Medical Centre, Bronx, New York 10467, USA. AN - 8749239 AU - Lipton, R. B. AU - Stewart, W. F. AU - Von Korff, M. DA - Oct DO - 10.1111/j.1468-2982.1995.Tb00041.X DP - NLM ET - 1995/10/01 KW - Absenteeism Activities of Daily Living/*classification Adolescent Adult Aged Cost of Illness Cross-Sectional Studies *Disability Evaluation Female Humans Male Middle Aged Migraine Disorders/classification/*diagnosis/epidemiology/therapy LA - eng N1 - Lipton, R B Stewart, W F Von Korff, M Journal Article Review England Cephalalgia. 1995 Oct;15 Suppl 15:4-9. doi: 10.1111/J.1468-2982.1995.TB00041.X. PY - 1995 SN - 0333-1024 (Print) 0333-1024 SP - 4-9 ST - Migraine impact and functional disability T2 - Cephalalgia TI - Migraine impact and functional disability VL - 15 Suppl 15 ID - 3173 ER - TY - JOUR AB - AIMS: The aim of this study was to determine the prevalence of pain that is related to temporomandibular disorders (TMD), gender differences, and perceived treatment need in children and adolescents at a public dental clinic in Linköping, Sweden. METHODS: A total of 862 children and adolescents aged 12 to 18 years received a questionnaire and their jaw opening was measured. Those who reported pain once a week or more in the masticatory system received a more comprehensive examination, including the Research Diagnostic Criteria for TMD and a neurologic examination (group 1). Group 2 reported pain less than once a week. RESULTS: Seven percent of subjects (63/862) were diagnosed with TMD pain. Both genders exhibited similar distributions of TMD diagnoses, except that myofascial pain was significantly more common in girls than in boys. Prevalence of pain once a week or more was reported as: 21% in the head; 12% in the temples; and 3% in the face, temporomandibular joint, or jaws. The prevalence of TMD-related pain was significantly higher in girls than in boys. Self-reported TMD symptoms were significantly more common (P < 0.001) in group 1. No significant gender differences were found in group 1 for pain intensity, behavioral rating scale scores, medicine consumption, reported days of school absence, or perceived need for treatment. CONCLUSION: Overall, TMD-related pain was more common in girls than in boys. A majority of children and adolescents who experienced pain once a week or more perceived a need for treatment. Seven percent of the examined subjects were diagnosed with TMD pain. AD - TMD Unit, Specialist Centre for Oral Rehabilitation, Linköping, Sweden. Thomas.List@oralrehab.ftv.lio.se AN - 10425964 AU - List, T. AU - Wahlund, K. AU - Wenneberg, B. AU - Dworkin, S. F. DA - Winter DP - NLM ET - 1999/07/30 IS - 1 KW - Adolescent Chi-Square Distribution Child Chronic Disease Cross-Sectional Studies Facial Pain/*etiology Female Humans Linear Models Male Needs Assessment Pain Measurement Prevalence Range of Motion, Articular Sex Factors Sound Statistics, Nonparametric Surveys and Questionnaires Sweden/epidemiology Temporomandibular Joint Disorders/complications/*epidemiology Temporomandibular Joint Dysfunction Syndrome/complications/epidemiology Tension-Type Headache/etiology LA - eng N1 - List, T Wahlund, K Wenneberg, B Dworkin, S F DEO8773/DE/NIDCR NIH HHS/United States Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. United States J Orofac Pain. 1999 Winter;13(1):9-20. PY - 1999 SN - 1064-6655 (Print) 1064-6655 SP - 9-20 ST - TMD in children and adolescents: prevalence of pain, gender differences, and perceived treatment need T2 - J Orofac Pain TI - TMD in children and adolescents: prevalence of pain, gender differences, and perceived treatment need VL - 13 ID - 3281 ER - TY - JOUR AB - Objective:To study the etiology of vertigo in children and analyze the relationship between the etiology of vertigo and the age category. Method:One hundred and forty-four cases of children with vertigo or dizziness were selected. All patients received the vertigo questionnaire, audiological, vestibular function and other related examinations. JMP 10.0 was used for statistical analysis. Result:Of 144 patients, 17 cases were preschool age (<6 years old), 101 cases were school age (6-12 years old) and 26 cases were puberty (>12 years old). All patients were mainly distributed between 6 and 10 years old. The most common diagnoses was benign paroxysmal vertigo. The second one was vestibular migraine. Incidence rate of the same disease in different ages was also different. Benign paroxysmal vertigo and vestibular migraine in preschool age, school age and puberty accounted for 58.8%, 42.6%, 0 and 0, 17.8%, 30.8%, respectively. Conclusion:Benign paroxysmal vertigo and vestibular migraine were the most common causes of vertigo in children. Prevalence rate and the etiology was various in different ages. Due to the physical and psychological development of children, analyzing the cause of vertigo in children should be fully considered these characteristics. AD - National Center for Children's Health, Department of Otorhinolaryngology Head and Neck Surgery, Beijing Children' s Hospital, Capital Medical University, Beijing, 100045, China. AN - 31163523 AU - Liu, B. AU - Li, B. AU - Zhang, L. AU - Liu, W. AU - Chen, M. AU - Hao, J. S. AU - Yang, Y. AU - Zhang, J. DA - Jun DO - 10.13201/j.issn.1001-1781.2019.06.008 DP - NLM ET - 2019/06/05 IS - 6 KW - *Benign Paroxysmal Positional Vertigo/complications/epidemiology Child Child, Preschool Dizziness Humans *Migraine Disorders/complications Prevalence Puberty *Vestibule, Labyrinth etiology vertigo relevant financial relationships with commercial interests to disclose. LA - chi N1 - Liu, B Li, B Zhang, L Liu, W Chen, M Hao, J S Yang, Y Zhang, J Journal Article China Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2019 Jun;33(6):508-511. doi: 10.13201/j.issn.1001-1781.2019.06.008. PY - 2019 SN - 2096-7993 (Print) 2096-7993 SP - 508-511 ST - [Correlation analysis of vertigo etiology and age in children] T2 - Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi TI - [Correlation analysis of vertigo etiology and age in children] VL - 33 ID - 3719 ER - TY - JOUR AB - PURPOSE: To evaluate the impact on learning outcomes of flipping a pain management module in a doctor of pharmacy curriculum. METHOD: In a required first-professional-year pharmacology and therapeutics course at the University of Maryland School of Pharmacy, the pain therapeutics content of the pain management module was flipped. This redesign transformed the module from a largely lecture-based, instructor-centered model to a learner-centered model that included a variety of preclass activities and in-class active learning exercises. In spring 2015, the module was taught using the traditional model; in spring 2016, it was taught using the flipped model. The same end-of-module objective structured clinical exam (OSCE) and multiple-choice exam were administered in 2015 to the traditional cohort (TC; n = 156) and in 2016 to the flipped cohort (FC; n = 162). Cohort performance was compared. RESULTS: Learning outcomes improved significantly in the FC: The mean OSCE score improved by 12.33/100 points (P < .0001; 95% CI 10.28-14.38; effect size 1.33), and performance on the multiple-choice exam's therapeutics content improved by 5.07 percentage points (P < .0001; 95% CI 2.56-7.59; effect size 0.45). Student performance on exam items assessing higher cognitive levels significantly improved under the flipped model. Grade distribution on both exams shifted, with significantly more FC students earning an A or B and significantly fewer earning a D or F compared with TC students. CONCLUSIONS: Student performance on knowledge- and skill-based assessments improved significantly after flipping the therapeutics content of a pain management module. AD - K. Lockman is clinical assistant professor, Department of Pharmacy Practice and Science, Division of Applied Clinical Sciences, University of Iowa College of Pharmacy, Iowa City, Iowa; ORCID: http://orcid.org/0000-0001-8017-8084. S.T. Haines is professor and director, Division of Pharmacy Professional Development, University of Mississippi School of Pharmacy, Jackson, Mississippi; ORCID: http://orcid.org/ 0000-0001-8217-1871. M.L. McPherson is professor and executive director, Advanced Post-Graduate Education in Palliative Care, Department of Pharmacy Practice and Science, University of Maryland School of Pharmacy, Baltimore, Maryland. AN - 28562458 AU - Lockman, K. AU - Haines, S. T. AU - McPherson, M. L. DA - Dec DO - 10.1097/acm.0000000000001742 DP - NLM ET - 2017/06/01 IS - 12 KW - Adolescent Adult *Curriculum *Education, Pharmacy/methods *Educational Measurement/methods Humans *Pain Management/methods *Problem-Based Learning/methods LA - eng N1 - 1938-808x Lockman, Kashelle Haines, Stuart T McPherson, Mary Lynn Comparative Study Controlled Clinical Trial Journal Article United States Acad Med. 2017 Dec;92(12):1786-1793. doi: 10.1097/ACM.0000000000001742. PY - 2017 SN - 1040-2446 SP - 1786-1793 ST - Improved Learning Outcomes After Flipping a Therapeutics Module: Results of a Controlled Trial T2 - Acad Med TI - Improved Learning Outcomes After Flipping a Therapeutics Module: Results of a Controlled Trial VL - 92 ID - 3603 ER - TY - JOUR AB - OBJECTIVE: To explore methodological refinements in measuring health-related lost productivity and to assess the business implications of a full-cost approach to managing health. METHODS: Health-related lost productivity was measured among 10 employers with a total of 51,648 employee respondents using the Health and Work Performance Questionnaire combined with 1,134,281 medical and pharmacy claims. Regression analyses were used to estimate the associations of health conditions with absenteeism and presenteeism using a range of models. RESULTS: Health-related productivity costs are significantly greater than medical and pharmacy costs alone (on average 2.3 to 1). Chronic conditions such as depression/anxiety, obesity, arthritis, and back/neck pain are especially important causes of productivity loss. Comorbidities have significant non-additive effects on both absenteeism and presenteeism. Executives/Managers experience as much or more monetized productivity loss from depression and back pain as Laborers/Operators. Testimonials are reported from participating companies on how the study helped shape their corporate health strategies. CONCLUSIONS: A strong link exists between health and productivity. Integrating productivity data with health data can help employers develop effective workplace health human capital investment strategies. More research is needed to understand the impacts of comorbidity and to evaluate the cost effectiveness of health and productivity interventions from an employer perspective. AD - Alere Brentwood, Tennesse, USA. ron.loeppke@alere.com AN - 19339899 AU - Loeppke, R. AU - Taitel, M. AU - Haufle, V. AU - Parry, T. AU - Kessler, R. C. AU - Jinnett, K. DA - Apr DO - 10.1097/JOM.0b013e3181a39180 DP - NLM ET - 2009/04/03 IS - 4 KW - Absenteeism Adolescent Adult *Chronic Disease/economics/epidemiology Commerce/*economics/organization & administration Comorbidity *Efficiency Efficiency, Organizational/*economics Female Health Status Humans Insurance Claim Review/economics Male Middle Aged Prevalence Regression Analysis Workplace/economics Young Adult LA - eng N1 - 1536-5948 Loeppke, Ronald Taitel, Michael Haufle, Vince Parry, Thomas Kessler, Ronald C Jinnett, Kimberly Journal Article Multicenter Study Research Support, Non-U.S. Gov't United States J Occup Environ Med. 2009 Apr;51(4):411-28. doi: 10.1097/JOM.0b013e3181a39180. PY - 2009 SN - 1076-2752 SP - 411-28 ST - Health and productivity as a business strategy: a multiemployer study T2 - J Occup Environ Med TI - Health and productivity as a business strategy: a multiemployer study VL - 51 ID - 3748 ER - TY - JOUR AB - Objectives: The objective of this study was to compare children and adolescents with overlapping chronic pains (OCP) to those with single chronic pains (SCP) among youth presenting in specialized clinical settings, in an effort to identify potential risk factors for developing overlapping pains. Methods: A total of 1235 youth ages 8 to 18 seen in a tertiary care multidisciplinary pain clinic or a multidisciplinary headache clinic completed self-report measures of pain, disability, psychological functioning and clinical history and characteristics at the time of initial clinic visit. Information was captured in a chronic pain data repository and accessed for the current study. Results: Subsequent pain symptoms developed on average 11.9 months (SD=24.5 mo) after onset of the first pain symptom. Compared with patients with SCP, patients with OCP report more medical comorbidity, more developmental issues, and poorer current sleep and school functioning. They also scored significantly higher than patients with SCP on self-reported functional disability, pain catastrophizing, fear of pain, depression, anxiety, and psychological stress and lower quality of life (all Ps<0.001). In multivariate analysis, variables most strongly associated with presenting with OCP were age (odds ratio [OR]: 1.1, P<0.001), having a clinically significant high functional disability (OR: 1.4, P=0.3), and low quality of life (OR: 2.5, P<0.001). Discussion: Given their tendency toward more psychological and medical comorbidities, patients with OCP may require more intense and diverse treatment approaches. Some early life experiences may be a risk factor for development of OCP. Longitudinal studies are needed to fully evaluate the heightened risk for OCP associated with some of these factors. AN - WOS:000656197400002 AU - Logan, D. E. AU - Donado, C. AU - Kaczynski, K. AU - Lebel, A. AU - Schechter, N. DA - Jun DO - 10.1097/ajp.0000000000000939 IS - 6 N1 - Logan, Deirdre E. Donado, Carolina Kaczynski, Karen Lebel, Alyssa Schechter, Neil 1536-5409 PY - 2021 SN - 0749-8047 SP - 404-412 ST - From One Pain to Many The Emergence of Overlapping Pains in Children and Adolescents T2 - Clinical Journal of Pain TI - From One Pain to Many The Emergence of Overlapping Pains in Children and Adolescents UR - ://WOS:000656197400002 VL - 37 ID - 1736 ER - TY - JOUR AB - Parental responses to children with chronic pain have been shown to influence the extent of the child's functional disability, but these associations have not been well studied in relation to children's pain-related school functioning. The current study tests the hypothesis that parental pain catastrophizing and parental protective responses to child pain influence the extent of school impairment in children with chronic pain. A mediational model was tested to determine whether parental protective behaviors serve a mediating role between parental pain catastrophizing and child school impairment. Study participants were a clinical sample of 350 children ages 8-17 years with chronic pain and their parents. Measures of pain characteristics, demographic characteristics, child depressive symptoms, school attendance rates, overall school functioning, parental pain catastrophizing, and parental protective responses to pain were collected. Results show that, controlling for the known influences of pain intensity and child depressive symptoms, parental pain catastrophizing and parental protective responses to child pain each independently predict child school attendance rates and reports of overall school impairment. Parental protectiveness was found to mediate the association between parental cognitions (i.e., parent pain catastrophizing) and child school functioning outcomes. These findings underscore the importance of intervening with parents to foster parental responses to child pain that help children engage and succeed in the school environment despite pain. AU - Logan, Deirdre E. AU - Simons, Laura E. AU - Carpino, Elizabeth A. DA - 2012/02// DO - 10.1016/j.pain.2011.11.004 DP - PubMed IS - 2 J2 - Pain KW - Absenteeism Adolescent Adult Catastrophization Child Chronic Pain Female Humans Male Parent-Child Relations Parents Schools Sick Role LA - eng PY - 2012 SN - 1872-6623 SP - 437-443 ST - Too sick for school? T2 - Pain TI - Too sick for school? Parent influences on school functioning among children with chronic pain UR - http://www.ncbi.nlm.nih.gov/pubmed/22169177 VL - 153 ID - 102 ER - TY - JOUR AB - Background: Virtual reality (VR) and augmented reality (AR) interventions are emerging as promising tools in the treatment of pediatric chronic pain conditions. However, in this young field, there is little consensus to guide the process of engaging in the development and evaluation of targeted VR-based interventions. Objective: The INOVATE-Pain (Interdisciplinary Network on Virtual and Augmented Technologies for Pain management) consortium aims to advance the field of VR for pediatric chronic pain rehabilitation by providing guidance for best practices in the design, evaluation, and dissemination of VR-based interventions targeting this population. Methods: An interdisciplinary meeting of 16 academics, clinicians, industry partners, and philanthropy partners was held in January 2020. Results: Reviewing the state of the field, the consortium identified important directions for research-driven innovation in VR and AR clinical care, highlighted key opportunities and challenges facing the field, and established a consensus on best methodological practices to adopt in future efforts to advance the research and practice of VR and AR in pediatric pain. The consortium also identified important next steps to undertake to continue to advance the work in this promising new area of digital health pain interventions. Conclusions: To realize the promise of this realm of innovation, key ingredients for success include productive partnerships among industry, academic, and clinical stakeholders; a uniform set of outcome domains and measures for standardized evaluation; and widespread access to the latest opportunities, tools, and resources. The INOVATE-Pain collaborative hopes to promote the creation, rigorous yet efficient evaluation, and dissemination of innovative VR-based interventions to reduce pain and improve quality of life for children. AN - WOS:000646922900004 AU - Logan, D. E. AU - Simons, L. E. AU - Caruso, T. J. AU - Gold, J. I. AU - Greenleaf, W. AU - Griffin, A. AU - King, C. D. AU - Menendez, M. AU - Olbrecht, V. A. AU - Rodriguez, S. AU - Silvia, M. AU - Stinson, J. N. AU - Wang, E. E. AU - Williams, S. E. AU - Wilson, L. C7 - e25916 DA - Apr DO - 10.2196/25916 IS - 4 N1 - Logan, Deirdre E. Simons, Laura E. Caruso, Thomas J. Gold, Jeffrey, I Greenleaf, Walter Griffin, Anya King, Christopher D. Menendez, Maria Olbrecht, Vanessa A. Rodriguez, Samuel Silvia, Megan Stinson, Jennifer N. Wang, Ellen Williams, Sara E. Wilson, Luke King, Christopher/0000-0002-0089-7386; Simons, Laura E./0000-0002-3395-9483; Menendez, Maria/0000-0001-9857-1589; Olbrecht, Vanessa/0000-0001-9110-0282; Gold, Jeffrey I./0000-0003-4493-1299 PY - 2021 SN - 1438-8871 ST - Leveraging Virtual Reality and Augmented Reality to Combat Chronic Pain in Youth: Position Paper From the Interdisciplinary Network on Virtual and Augmented Technologies for Pain Management T2 - Journal of Medical Internet Research TI - Leveraging Virtual Reality and Augmented Reality to Combat Chronic Pain in Youth: Position Paper From the Interdisciplinary Network on Virtual and Augmented Technologies for Pain Management UR - ://WOS:000646922900004 VL - 23 ID - 1739 ER - TY - JOUR AB - PURPOSE: Music therapy has shown benefits for reducing distress in individuals with cancer. We explore the effects of music therapy on self-reported symptoms of patients receiving inpatient care at a comprehensive cancer center. METHODS: Music therapy was available as part of an inpatient integrative oncology consultation service; we examined interventions and symptoms for consecutive patients treated by a board-certified music therapist from September 2016 to May 2017. Patients completed the Edmonton Symptom Assessment Scale (ESAS, 10 symptoms, scale 0-10, 10 most severe) before and after the intervention. Data was summarized by descriptive statistics. Changes in ESAS symptom and subscale scores (physical distress (PHS), psychological distress (PSS), and global distress (GDS)) were evaluated by Wilcoxon signed rank test. RESULTS: Data were evaluable for 96 of 100 consecutive initial, unique patient encounters; 55% were women, average age 50, and majority with hematologic malignancies (47%). Reasons for music therapy referral included anxiety/stress (67%), adjustment disorder/coping (28%), and mood elevation/depression (17%). The highest (worst) symptoms at baseline were sleep disturbance (5.7) and well-being (5.5). We observed statistically and clinically significant improvement (means) for anxiety (- 2.3 ± 1.5), drowsiness (- 2.1 ± 2.2), depression (- 2.1 ± 1.9), nausea (- 2.0 ± 2.4), fatigue (- 1.9 ± 1.5), pain (- 1.8 ± 1.4), shortness of breath (- 1.4 ± 2.2), appetite (- 1.1 ± 1.7), and for all ESAS subscales (all ps < 0.02). The highest clinical response rates were observed for anxiety (92%), depression (91%), and pain (89%). CONCLUSIONS: A single, in-person, tailored music therapy intervention as part of an integrative oncology inpatient consultation service contributed to the significant improvement in global, physical, and psychosocial distress. A randomized controlled trial is justified. AD - Integrative Medicine Center, Department of Palliative, Rehabilitation and Integrative Medicine, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd Unit 1414, Houston, TX, 77030, USA. gabriel.lopez@mdanderson.org. Department of Palliative, Rehabilitation and Integrative Medicine, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA. Texas College of Osteopathic Medicine, University of North Texas Health Science Center, Fort Worth, TX, USA. Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. AN - 30825024 AU - Lopez, G. AU - Christie, A. J. AU - Powers-James, C. AU - Bae, M. S. AU - Dibaj, S. S. AU - Gomez, T. AU - Williams, J. L. AU - Bruera, E. DA - Nov DO - 10.1007/s00520-019-04713-4 DP - NLM ET - 2019/03/03 IS - 11 KW - Adolescent Adult Aged Anxiety/psychology/therapy Appetite Child Child, Preschool Depression/psychology/therapy Fatigue/therapy Female Hospitalization Humans Inpatients/*psychology Male Middle Aged Music Therapy/*statistics & numerical data Nausea/therapy Neoplasms/psychology/therapy Pain Pain Management *Psychological Distress Self Report/*statistics & numerical data Sleep Young Adult Complementary health approach Integrative medicine Integrative oncology Music therapy Patient-reported outcomes LA - eng N1 - 1433-7339 Lopez, Gabriel Orcid: 0000-0002-3685-0280 Christie, Aimee J Powers-James, Catherine Bae, Mi Sun Dibaj, Seyedeh S Gomez, Telma Williams, Janet L Bruera, Eduardo Integrative Health Initiative/Duncan Family Institute for Cancer Prevention and Risk Assessment/ Journal Article Germany Support Care Cancer. 2019 Nov;27(11):4207-4212. doi: 10.1007/s00520-019-04713-4. Epub 2019 Mar 1. PY - 2019 SN - 0941-4355 SP - 4207-4212 ST - The effects of inpatient music therapy on self-reported symptoms at an academic cancer center: a preliminary report T2 - Support Care Cancer TI - The effects of inpatient music therapy on self-reported symptoms at an academic cancer center: a preliminary report VL - 27 ID - 3729 ER - TY - JOUR AB - BACKGROUND: Prevention of sickness absence (SA) is a major public health challenge. Sufficient levels of physical activity may be an important protective factor. In contrast to the North European countries, little is known about physical activity behavior and its influence over SA in South European countries. METHODS: In the European Health Interview Survey (EHIS) 2014, a total of 9512 Spanish workers aged 17 to 70 (46.5% women) replied to questions about SA (last 12 months) and the frequency of leisure-time physical activity (LTPA). Multiple linear regression adjusted for age, sex, education, occupational class, smoking habits, body mass index, and chronic disease (diabetes, hypertension, neck pain, low back pain, chronic depression and anxiety) was used to assess associations. RESULTS: The average SA among the participants was 6.9 days (SD=33.3) per year, whereas the prevalence of any SA episode was 22.0%. The prevalence of workers performing high or very high LTPA was 31.0%. In final sex and age-stratified fully adjusted models, the association between LTPA and SA remained significant for women aged 44 to 51 (β=-0.07, 95% CI: -0.42 to -0.03) for SA. CONCLUSIONS: The results suggest that higher LTPA is associated with lower SA in a particular category of workers, that might benefit from physical activity strategies. AD - Department of Physical Medicine and Nursing, University of Zaragoza, Zaragoza, Spain - rlopezbu@unizar.es. National Research Center for the Working Environment, Copenhagen, Denmark - rlopezbu@unizar.es. National Research Center for the Working Environment, Copenhagen, Denmark. Exercise Intervention for Health Research Group (EXINH-RG), Department of Physiotherapy, University of Valencia, Spain. Faculty of Sport Sciences, University of Murcia, Murcia Spain. The Cambridge Centre for Sports and Exercise Sciences, Anglia Ruskin University, Cambridge, UK. Department of Health Science and Technology, Aalborg University, Aalborg, Denmark. Faculty of Health Sciences, University of Zaragoza, Zaragoza, Spain. GENUD (Growth, Exercise, Nutrition and Development) Research Group, University of Zaragoza, Zaragoza, Spain. Biomedical Research Networking Center about Nutrition and Obesity Physiopathology (CIBER-OBN), Madrid, Spain. AN - 32162505 AU - López-Bueno, R. AU - Calatayud, J. AU - López-Sánchez, G. F. AU - Smith, L. AU - Andersen, L. L. AU - Casajús, J. A. DA - Jun DO - 10.23736/s0022-4707.20.10434-1 DP - NLM ET - 2020/03/13 IS - 6 KW - Absenteeism Adolescent Adult Aged Body Mass Index Cross-Sectional Studies Europe *Exercise Female Health Surveys Humans *Leisure Activities Male Middle Aged Motor Activity Prevalence Sick Leave/*statistics & numerical data Workforce/*statistics & numerical data Young Adult LA - eng N1 - 1827-1928 López-Bueno, Rubén Calatayud, Joaquín López-Sánchez, Guillermo F Smith, Lee Andersen, Lars L Casajús, José A Journal Article Italy J Sports Med Phys Fitness. 2020 Jun;60(6):919-925. doi: 10.23736/S0022-4707.20.10434-1. Epub 2020 Mar 11. PY - 2020 SN - 0022-4707 SP - 919-925 ST - Higher leisure-time physical activity is associated with lower sickness absence: cross-sectional analysis among the general workforce T2 - J Sports Med Phys Fitness TI - Higher leisure-time physical activity is associated with lower sickness absence: cross-sectional analysis among the general workforce VL - 60 ID - 3724 ER - TY - JOUR AB - OBJECTIVES: To examine the prevalence and patterns of nonmedical use of prescription opioid analgesics and stimulants among student pharmacists. DESIGN: Descriptive, nonexperimental, cross-sectional study. SETTING: Private urban college of pharmacy in the United States in fall 2006. PARTICIPANTS: 1,538 PharmD students. INTERVENTION: Online survey. MAIN OUTCOME MEASURES: Lifetime and past-year nonmedical prescription opioid and stimulant use. RESULTS: Response rate for the survey was 62%. Lifetime prevalence of opioid misuse was 8%, and 5% of students had misused in the past year. Lifetime prevalence of stimulant misuse was 7%, and 5% had misused in the past year. Whites and fraternity or sorority members were more likely than their peers to have ever misused opioids. Past-year opioid misuse was more likely among whites, men, and low academic achievers compared with their peers. Lifetime stimulant misuse was more likely among students who were white, older, and fraternity or sorority members, while past-year misuse was more likely among whites and low academic achievers. Common motives for opioid misuse were to have fun, to relax, and to deal with chronic pain. Stimulants were used to improve concentration and academic performance. Friends were the most common source of prescription opioids and stimulants. Nonmedical prescription use was associated with greater likelihood of alcohol and other illicit substance use. CONCLUSION: The prevalence of prescription medication misuse among student pharmacists was lower than (opioids) or comparable with (stimulants) reported rates in college populations. Subgroups of students demonstrated higher rates of nonmedical use, including whites, students involved with fraternities or sororities, and low academic achievers. That friends were the primary source of misused medications indicates that diversion of prescription-only controlled substances likely occurs among student pharmacists. Nonmedical prescription medication use should be considered in the context of other substance use. AD - National Development and Research Institutes, Inc, New York, USA. lord@ndri.org AN - 19589764 AU - Lord, S. AU - Downs, G. AU - Furtaw, P. AU - Chaudhuri, A. AU - Silverstein, A. AU - Gammaitoni, A. AU - Budman, S. DA - Jul-Aug DO - 10.1331/JAPhA.2009.08027 DP - NLM ET - 2009/07/11 IS - 4 KW - Adolescent Adult Alcohol Drinking/epidemiology *Analgesics, Opioid Attention/drug effects *Central Nervous System Stimulants Cross-Sectional Studies Educational Status European Continental Ancestry Group/statistics & numerical data Female Health Surveys Humans Male Opioid-Related Disorders/*epidemiology/ethnology Pain/drug therapy Peer Group *Prescription Drugs Prevalence Recreation Risk Factors Schools, Pharmacy/*statistics & numerical data Sex Factors Smoking/epidemiology Students, Pharmacy/*statistics & numerical data Substance-Related Disorders/*epidemiology/ethnology Surveys and Questionnaires United States/epidemiology Young Adult LA - eng N1 - 1544-3450 Lord, Sarah Downs, George Furtaw, Paul Chaudhuri, Anamika Silverstein, Amy Gammaitoni, Arnold Budman, Simon Journal Article Research Support, Non-U.S. Gov't United States J Am Pharm Assoc (2003). 2009 Jul-Aug;49(4):519-28. doi: 10.1331/JAPhA.2009.08027. PY - 2009 SN - 1086-5802 SP - 519-28 ST - Nonmedical use of prescription opioids and stimulants among student pharmacists T2 - J Am Pharm Assoc (2003) TI - Nonmedical use of prescription opioids and stimulants among student pharmacists VL - 49 ID - 4165 ER - TY - JOUR AB - PurposeThe prevalence of temporomandibular disorders (TMD) in the general Polish population has not yet been thoroughly investigated. The aim of this study was to determine how frequently Polish young adults demonstrated the signs and symptoms of TMD, and how often they were aware of these. Materials and MethodsThe study involved 260 volunteers of approximately 18 years of age (and with an F:M ratio of 2.8), who had completed the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) questionnaire in its internationally accepted Polish version. The volunteers were students from three randomly selected high schools in Krakow, Poland. Following the clinical examinations, all participants received none or one or more of the RDC/TMD axis I diagnoses on one or both sides: muscle disorders (group I), disk displacements (group II), arthralgia, osteoarthritis, and osteoarthrosis (group III). Classification on RDC/TMD axis II involved pain-related impairment (Graded Chronic Pain Severity, from 0: no TMD pain in the prior 6 months, to IV: high disabilityseverely limiting), depression, and somatization levels (normal, moderate, severe). ResultsOn the RDC/TMD axis I, 69 (26.5%) of the participants received one or more of the possible diagnoses. Awareness of TMD was present in 20 (7.7%) people from that group, in the form of self-complaints. The difference between females and males was statistically significant (p = 0.0013). On the RDC/TMD axis II assessment, a diagnosis of pain, depression, or somatization was given in 38 (14.6%) cases from that group. ConclusionMuscle disorders were most frequently diagnosed in the group of Polish young adults, and the prevalence of the disease did not differ across similar groups of young people. AN - WOS:000403791400004 AU - Loster, J. E. AU - Osiewicz, M. A. AU - Groch, M. AU - Ryniewicz, W. AU - Wieczorek, A. DA - Jun DO - 10.1111/jopr.12414 IS - 4 N1 - Loster, Jolanta E. Osiewicz, Magdalena A. Groch, Magdalena Ryniewicz, Wojciech Wieczorek, Aneta Loster, Jolanta E./N-7581-2019; Wieczorek, Aneta/AAB-8844-2019 Loster, Jolanta E./0000-0002-8759-0810; Wieczorek, Aneta/0000-0003-2506-7394 1532-849x PY - 2017 SN - 1059-941X SP - 284-288 ST - The Prevalence of TMD in Polish Young Adults T2 - Journal of Prosthodontics-Implant Esthetic and Reconstructive Dentistry TI - The Prevalence of TMD in Polish Young Adults UR - ://WOS:000403791400004 VL - 26 ID - 2094 ER - TY - JOUR AB - Chronic pain and the opioid epidemic need early, upstream interventions to aim at meaningful downstream behavioral changes. A recent pain neuroscience education (PNE) program was developed and tested for middle-school students to increase pain knowledge and promote healthier beliefs regarding pain. In this study, 668 seventh-grade middle-school students either received a PNE lecture (n= 220); usual curriculum school pain education (UC) (n= 198) or PNE followed by two booster (PNEBoost) sessions (n= 250). Prior to, immediately after and at six-month follow-up, pain knowledge and fear of physical activity was measured. Six months after the initial intervention school, physical education, recess and sports attendance/participation as well as healthcare choices for pain (doctor visits, rehabilitation visits and pain medication use) were measured. Students receiving PNEBoost used 30.6% less pain medication in the last 6 months compared to UC (p= 0.024). PNEBoost was superior to PNE for rehabilitation visits in students experiencing pain (p= 0.01) and UC for attending school in students who have experienced pain > 3 months (p= 0.004). In conclusion, PNEBoost yielded more positive behavioral results in middle school children at six-month follow-up than PNE and UC, including significant reduction in pain medication use. AN - WOS:000554608200001 AU - Louw, A. AU - Landrus, R. AU - Podolak, J. AU - Benz, P. AU - DeLorenzo, J. AU - Davis, C. AU - Rogers, A. AU - Cooper, K. AU - Louw, C. AU - Zimney, K. AU - Puentedura, E. J. AU - Landers, M. R. C7 - 4505 DA - Jun DO - 10.3390/ijerph17124505 IS - 12 N1 - Louw, Adriaan Landrus, Regina Podolak, Jessie Benz, Patricia DeLorenzo, Jen Davis, Christine Rogers, Alison Cooper, Kathy Louw, Colleen Zimney, Kory Puentedura, Emilio J. Landers, Merrill R. ; Landers, Merrill/P-6359-2014 Puentedura, Emilio/0000-0003-4771-4732; Landers, Merrill/0000-0002-4234-910X; Zimney, Kory/0000-0002-7513-2126; Davis, Christine/0000-0002-3132-4978 1660-4601 PY - 2020 ST - Behavior Change Following Pain Neuroscience Education in Middle Schools: A Public Health Trial T2 - International Journal of Environmental Research and Public Health TI - Behavior Change Following Pain Neuroscience Education in Middle Schools: A Public Health Trial UR - ://WOS:000554608200001 VL - 17 ID - 1818 ER - TY - JOUR AB - Pain neuroscience education (PNE) is an educational strategy aimed at teaching people more about pain from a neurobiological and neurophysiological perspective. Current best-evidence provides strong support for PNE to positively influence pain ratings, dysfunctions, fear-avoidance and pain catastrophization, limitations in movement, pain knowledge, and healthcare utilization. To date, all PNE studies have been conducted on adult populations. This study set out to explore if an abbreviated PNE lecture to middle school children would result in a positive shift in pain knowledge as well as healthier beliefs regarding pain. One-hundred-and-thirty-three middle school students spanning 5th to 8th grade attended a 30-minute PNE lecture. The primary outcome measures of pain knowledge (neurophysiology of pain questionnaire [NPQ]) and beliefs regarding pain (numeric rating scale) were measured before and immediately after the PNE lecture. Significant improvement in knowledge was found with mean score on NPQ test scores improving from 3.83 (29.5%) pre-PNE to 7.90 (60.8%) post-PNE (p<0.001), with a large effect size (r=.711). Significant shifts in beliefs were also found in all but one of the pain beliefs questions, with a medium effect size for you can control how much pain you feel (p<0.001; r=0.354) and large effect size for your brain decides if you feel pain, not your tissues (p<0.001; r=0.545). This study shows that a 30-minute PNE lecture to middle school children resulted in a significant increase in their knowledge of pain as well various beliefs regarding pain. AN - WOS:000428593500005 AU - Louw, A. AU - Podalak, J. AU - Zimney, K. AU - Schmidt, S. AU - Puentedura, E. J. DO - 10.1080/09593985.2017.1423142 IS - 7 N1 - Louw, Adriaan Podalak, Jessie Zimney, Kory Schmidt, Stephen Puentedura, Emilio J. Puentedura, Emilio J./AAG-7118-2020 Puentedura, Emilio J./0000-0003-4771-4732 1532-5040 PY - 2018 SN - 0959-3985 SP - 542-550 ST - Can pain beliefs change in middle school students? A study of the effectiveness of pain neuroscience education T2 - Physiotherapy Theory and Practice TI - Can pain beliefs change in middle school students? A study of the effectiveness of pain neuroscience education UR - ://WOS:000428593500005 VL - 34 ID - 2052 ER - TY - JOUR AB - Pediatric functional abdominal pain disorders (FAPD) are associated with adverse outcomes including increased somatization (e.g., heightened physiological sensations that include gastroenterological and non-gastroenterological symptoms) and increased functional disability. Caregiver distress and child anxiety are separately associated with the adverse outcomes of pediatric FAPD. However, the cumulative role of caregiver (i.e., stress, anxiety, and depression) and child psychological functioning (anxiety) in relation to adverse outcomes associated with FAPD, and particularly somatization, is unclear. Thus, the present investigation sought to examine the role of caregiver distress and child anxiety in relation to pain-related functioning (i.e., somatization, pain intensity, functional disability) in youth with FAPD. Data were gathered as part of a larger study examining a psychological treatment for youth with FAPD. Participants (ages 9-14) with FAPD completed measures of child anxiety, pain, and pain-related functioning. Caregivers completed a measure of caregiver distress (e.g., stress, anxiety, depressive symptoms). Pearson correlations revealed significant positive associations between child anxiety and child functional disability. Additionally, caregiver anxiety, child anxiety, and child somatization were all significantly and positively correlated with one another. Therefore, we assessed whether child anxiety may potentially mediate the relationship between caregiver anxiety and child somatization in this cross-sectional study. The indirect association between caregiver anxiety and child somatization via child anxiety was not significant. Future research including longitudinal designs to further understand the relationship between caregiver anxiety, child anxiety, and child pain-related functioning, would enhance understanding of how these potentially modifiable psychological factors may impact adverse outcomes of FAPD. AN - WOS:000505733000006 AU - Love, S. C. AU - Mara, C. A. AU - Kalomiris, A. E. AU - Cunningham, N. R. C7 - 134 DA - Dec DO - 10.3390/children6120134 IS - 12 N1 - Love, Sarah C. Mara, Constance A. Kalomiris, Anne E. Cunningham, Natoshia R. 2227-9067 PY - 2019 ST - The Influence of Caregiver Distress and Child Anxiety in Predicting Child Somatization in Youth with Functional Abdominal Pain Disorders T2 - Children-Basel TI - The Influence of Caregiver Distress and Child Anxiety in Predicting Child Somatization in Youth with Functional Abdominal Pain Disorders UR - ://WOS:000505733000006 VL - 6 ID - 1866 ER - TY - JOUR AB - Background: The importance of neonatal experience upon behaviour in later life is increasingly recognised. The overlap between pain and reward pathways led us to hypothesise that neonatal pain experience influences reward-related pathways and behaviours in adulthood. Methodology/Principal Findings: Rat pups received repeat plantar skin incisions (neonatal IN) or control procedures (neonatal anesthesia only, AN) at postnatal days (P)3, 10 and 17. When adult, rats with neonatal 'pain history' showed greater sensory sensitivity than control rats following acute plantar skin incision. Motivational behaviour in the two groups of rats was tested in a novelty-induced hypophagia (NIH) paradigm. The sensitivity of this paradigm to pain-induced changes in motivational behaviour was shown by significant increases in the time spent in the central zone of the arena (43.7 +/- 5.9% vs. 22.5 +/- 6.7%, p<0.05), close to centrally placed food treats, and decreased number of rears (9.5 +/- 1.4 vs. 19.2 +/- 2.3, p<0.001) in rats with acute plantar skin incision compared to naive, uninjured animals. Rats with a neonatal 'pain history' showed the same pain-induced behaviour in the novelty-induced hypophagia paradigm as controls. However, differences were observed in reward-related neural activity between the two groups. Two hours after behavioural testing, brains were harvested and neuronal activity mapped using c-Fos expression in lateral hypothalamic orexin neurons, part of a specific reward seeking pathway. Pain-induced activity in orexin neurons of control rats (18.4 +/- 2.8%) was the same as in uninjured naive animals (15.5 +/- 2.6%), but in those rats with a 'pain history', orexinergic activity was significantly increased (27.2 +/- 4.1%, p<0.01). Furthermore the extent of orexin neuron activation in individual rats with a 'pain history' was highly correlated with their motivational behaviour (r = 20.86, p = 0.01). Conclusions/Significance: These results show that acute pain alters motivational behaviour and that neonatal pain experience causes long-term changes in brain motivational orexinergic pathways, known to modulate mesolimbic dopaminergic reward circuitry. AN - WOS:000304489000095 AU - Low, L. A. AU - Fitzgerald, M. C7 - e34316 DA - Mar DO - 10.1371/journal.pone.0034316 IS - 3 N1 - Low, Lucie A. Fitzgerald, Maria Low, Lucie/0000-0001-6082-8625 PY - 2012 SN - 1932-6203 ST - Acute Pain and a Motivational Pathway in Adult Rats: Influence of Early Life Pain Experience T2 - Plos One TI - Acute Pain and a Motivational Pathway in Adult Rats: Influence of Early Life Pain Experience UR - ://WOS:000304489000095 VL - 7 ID - 2445 ER - TY - JOUR AB - The term 'growing pains' has been used for almost 200 years to refer to the often severe, generally bilateral lower-extremity nocturnal pains experienced by up to one-third of all children at some time during early childhood. No clear mechanism has yet been identified that explains these pains, but there is an increasing body of evidence indicating that several factors, individually or in combination, might be responsible for this phenomenon. These include mechanical factors, such as joint hypermobility and flat feet, decreased pain thresholds, reduced bone strength, and emotional factors involving the patient's family and other social stressors. Correct diagnosis of growing pains requires a thorough patient history and physical examination. The diagnosis can be safely established without unnecessary laboratory investigations or imaging; however, identification of one or more clinical cautionary signs, such as unilateral pain, morning stiffness, joint swelling and systemic symptoms (e. g. fever, weight loss and malaise), should trigger an extended evaluation to exclude other more serious conditions that might also present with limb pain. Once the diagnosis has been established, conservative management, using symptomatic pain medications, massage and other supportive measures, should be employed until the syndrome self-resolves with time. AN - WOS:000259550500011 AU - Lowe, R. M. AU - Hashkes, P. J. DA - Oct DO - 10.1038/ncprheum0903 IS - 10 N1 - Lowe, Robert M. Hashkes, Philip J. PY - 2008 SN - 1745-8382 SP - 542-549 ST - Growing pains: a noninflammatory pain syndrome of early childhood T2 - Nature Clinical Practice Rheumatology TI - Growing pains: a noninflammatory pain syndrome of early childhood UR - ://WOS:000259550500011 VL - 4 ID - 2636 ER - TY - JOUR AB - We examined retrospectively premorbid factors that might relate to the development of irritable bowel syndrome (IBS). We administered a semistructural interview to adult IBS patients, adults with symptoms of IBS who had not visited a doctor (nonpatients), and asymptomatic normals. Patients with IBS differed from nonpatients by reporting more severe bowel problems, more frequent doctor visits in childhood, and more pain associated with current bowel symptoms. These factors may contribute to the tendency of people with bowel symptoms to seek medical care. More patients, and in most cases nonpatients with IBS, reported poorer general health and headaches, stomachaches, and bowel complaints during childhood. They also showed evidence for greater parental attention to illness with more frequent school absences and doctor visits than normal subjects. Loss and separation during childhood, and in the current family, and conflicted or dependent maternal relationships were also more frequently reported among patients and nonpatients. These factors may contribute to the development of IBS. AN - 3611687 AU - Lowman, B. C. AU - Drossman, D. A. AU - Cramer, E. M. AU - McKee, D. C. DA - Jun DO - 10.1097/00004836-198706000-00017 DP - NLM ET - 1987/06/01 IS - 3 KW - Adult Attitude to Health Child Colonic Diseases, Functional/etiology/*psychology Family Female Gastrointestinal Diseases/psychology Headache/psychology Humans Interview, Psychological Life Change Events Male Medical History Taking Psychophysiologic Disorders/*etiology Retrospective Studies Surveys and Questionnaires LA - eng N1 - Lowman, B C Drossman, D A Cramer, E M McKee, D C AM29934/AM/NIADDK NIH HHS/United States Journal Article Research Support, U.S. Gov't, P.H.S. United States J Clin Gastroenterol. 1987 Jun;9(3):324-30. doi: 10.1097/00004836-198706000-00017. PY - 1987 SN - 0192-0790 (Print) 0192-0790 SP - 324-30 ST - Recollection of childhood events in adults with irritable bowel syndrome T2 - J Clin Gastroenterol TI - Recollection of childhood events in adults with irritable bowel syndrome VL - 9 ID - 3998 ER - TY - JOUR AB - Background: While lower socioeconomic status increases individual's risk for chronic conditions, little is known about how long-term social assistance recipients (LTRs) with multiple chronic health problems experience chronic pain and/or psychological distress. Social assistance is the last safety net in the Norwegian welfare system and individuals have a legal right to economic assistance if they are unable to support themselves or are entitled to other types of benefits. The purposes of this study were to determine the co-occurrence of both chronic pain and psychological distress and to evaluate for differences in demographic and social characteristics, as well as health-related quality of life, among LTRs. Methods: This descriptive, cross-sectional study surveyed people receiving long-term social assistance in Norway about their health and social functioning from January-November 2005. The social welfare authority offices in each of 14 municipalities in Norway were responsible to locate the LTRs who met the study's inclusion criteria. The selected municipalities provided geographic variability including both rural and urban municipalities in different parts of the country. LTRs were included in this study if they: had received social assistance as their main source of income for at least 6 of the last 12 months; were between 18 and 60 years of age; and were able to complete the study questionnaire. In this study, 405 LTRs were divided into four groups based on the presence or absence of chronic pain and/or psychological distress. (1) Neither chronic pain nor psychological distress (32%, n=119), (2) only chronic pain (12%, n=44), (3) only psychological distress and (24%, n=87), (4) both chronic pain and psychological distress (32%, n = 119). Results: Except for age and marital status, no differences were found between groups in demographic characteristics. Significant differences were found among the four groups on all of the items related to childhood difficulties before the age of 16, except the item on sexual abuse. LTRs with both chronic pain and psychological distress were more likely to have experienced economic problems in their childhood home; other types of abuse than sexual abuse; long-term bullying; and had more often dropped out of school than LTRs with neither chronic pain nor psychological distress. LTRs with both chronic pain and psychological distress, reported more alcohol and substance use/illicit drug use, more feelings of loneliness and a lower mental score on SF-12 than LTRs with only chronic pain. Conclusions and implications: Co-occurrence of chronic pain and psychological distress is common in LTRs and problems in early life are associated with the co-occurrence of chronic pain and psychological distress in adult life. Although this study cannot assign a clear direction or causality to the association between social and demographic characteristics and chronic pain and psychological distress, the findings when examining LTRs' problems in childhood before the age of 16, indicated that incidents in early life create a probability of chronic pain and psychological distress in the adult life of the individuals. Further studies should use life course studies and longitudinal data in to investigate these important questions in LTRs. (C) 2015 Scandinavian Association for the Study of Pain. Published by Elsevier B.V. All rights reserved. AN - WOS:000378138300012 AU - Loyland, B. DA - Apr DO - 10.1016/j.sjpain.2015.12.003 N1 - Loyland, Borghild 1877-8879 PY - 2016 SN - 1877-8860 SP - 65-72 ST - The co-occurrence of chronic pain and psychological distress and its associations with salient socio-demographic characteristics among long-term social assistance recipients in Norway T2 - Scandinavian Journal of Pain TI - The co-occurrence of chronic pain and psychological distress and its associations with salient socio-demographic characteristics among long-term social assistance recipients in Norway UR - ://WOS:000378138300012 VL - 11 ID - 2170 ER - TY - JOUR AB - BACKGROUND CONTEXT: Surgical indications and procedures for spinal Langerhans cell histiocytosis (LCH) in children are still controversial. Reports containing large samples of surgically treated patients are few in the currently available literature, and the reported operative procedures were also somewhat obsolete. So, further investigation based on large-sample cases and using improved surgical techniques is beneficial and helpful to refine the treatment strategy. PURPOSE: To recommend a reasonable treatment strategy for thoracic or lumbar spine LCH in children complicated with neurologic deficit. STUDY DESIGN/SETTING: Retrospective/academic medical center. PATIENT SAMPLE: Twelve children aged from 2 to 16 years old with the diagnosis of thoracic or lumbar spinal LCH accompanied by neurologic deficit received surgical treatment from January 2005 to January 2010. OUTCOME MEASURES: Frankel scale for neurologic function, fusion of the mass, and recurrence of the lesion. METHODS: All 12 patients presented initially with local pain and progressive neurologic detriment. Neurologic evaluation revealed two patients with Frankel Grade B, eight with Grade C, and two with Grade D. Radiographic features were positive for typical vertebra plana, a space-occupying mass in the spinal canal compressing neural elements, and a spinal canal encroachment rate more than 50%. Posterior instrumentation with pedicle screw combined with anterior corpectomy, decompression, and support bone graft was performed in the first seven patients as a one-stage procedure. In the remaining five patients, posterior pedicle screw fixation, laminectomy for decompression (via excision of the tumor-like mass), and repair of laminae with allograft bone block were performed. The collapsed vertebral body was left untouched. No chemotherapy or radiotherapy was administrated postoperatively in any of the cases. RESULTS: The mean follow-up duration was 43.3 months. The mean operation time was 330 minutes with combined procedure and 142 minutes with single posterior approach (p=.000). The average blood loss was 933 mL with combined procedure and 497 mL with single posterior approach (p=.039). Three of seven patients who received combined surgery encountered approach-related complications, that is, one with intercostal neuralgia and two with pleural effusion. No severe neurologic deteriorate, instrumentation failure, or disease recurrence was detected at follow-up. Neurologic function completely recovered in all 12 patients from 2 to 12 weeks after surgery. The anterior bone graft fused and shaped well in all seven patients, and allograft bone block for lamina repair also achieved complete fusion in the remaining five patients. The internal fixator was removed at 3 to 5 years (average 4.1 years) after initial operation in six patients. No deformity, including scoliosis and kyphosis, has been identified during follow-up period in both procedures. CONCLUSIONS: For spinal LCH patients, neurologic deficit is a main indication for operative treatment to prevent permanent and serious consequences. Surgery provides an opportunity for rapid recovery of neurologic function. Both combined and single-stage posterior approaches based on pedicle screw instrumentation techniques are similarly effective in relieving neurologic compression. However, single-stage posterior approach is more favorable with less complications, and preserving involved vertebral body is not a latent hazard of recurrence. (C) 2014 Elsevier Inc. All rights reserved. AN - WOS:000334770700008 AU - Lu, G. H. AU - Li, J. AU - Wang, X. B. AU - Wang, B. AU - Phan, K. DA - May DO - 10.1016/j.spinee.2013.06.104 IS - 5 N1 - Lu, Guo-Hua Li, Jing Wang, Xiao-Bin Wang, Bing Phan, Kevin 1878-1632 PY - 2014 SN - 1529-9430 SP - 768-776 ST - Surgical treatment based on pedicle screw instrumentation for thoracic or lumbar spinal Langerhans cell histiocytosis complicated with neurologic deficit in children T2 - Spine Journal TI - Surgical treatment based on pedicle screw instrumentation for thoracic or lumbar spinal Langerhans cell histiocytosis complicated with neurologic deficit in children UR - ://WOS:000334770700008 VL - 14 ID - 2308 ER - TY - JOUR AB - AIM: Functional gastrointestinal disorders (FGIDs) are common in children, but the epidemiology of FGIDs is incompletely understood. Our aim was to perform a population-based study using Rome III criteria to describe the prevalence of FGIDs in children in Panama. METHODS: We performed a cross-sectional study of children attending three schools in Panama City, Panama. Children with organic medical diseases were excluded. Subjects provided demographic information and completed the Questionnaire on Pediatric Gastrointestinal Symptoms - Rome III Spanish version. RESULTS: A total of 321 subjects (61.1% female, median age 10 years, range 8-14 years) completed our study. A total of 92 subjects (28.7%) met criteria for an FGID. Gender, age and school type did not differ significantly between subjects with and without FGIDs. The most common FGIDs included functional constipation (15.9%), irritable bowel syndrome (5.6%), and functional abdominal pain or functional abdominal pain syndrome (4.0%). Abdominal pain-related FGIDs were present in 12.1%. CONCLUSION: FGIDs are common in school-aged children in Panama. The prevalence of abdominal pain-related FGIDs in children in Panama is similar to that described in other parts of the world. Further population-based studies utilising Rome III criteria to measure FGID prevalence in children are needed to advance our understanding of the pathogenesis of FGIDs. AD - Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Nationwide Children's Hospital, Columbus, OH, USA. Department of Pediatrics, Hospital del Niño, Panama City, Panama. Department of Pediatrics, Universidad del Valle, Cali, Colombia. AN - 26933798 AU - Lu, P. L. AU - Saps, M. AU - Chanis, R. A. AU - Velasco-Benítez, C. A. DA - May DO - 10.1111/apa.13379 DP - NLM ET - 2016/03/05 IS - 5 KW - Adolescent Child Cross-Sectional Studies Female Gastrointestinal Diseases/diagnosis/*epidemiology Humans Male Panama/epidemiology Prevalence Schools Abdominal pain Constipation Developing countries Epidemiology Functional abdominal pain LA - eng N1 - 1651-2227 Lu, Peter L Saps, Miguel Chanis, Ricardo A Velasco-Benítez, Carlos A Journal Article Norway Acta Paediatr. 2016 May;105(5):e232-6. doi: 10.1111/apa.13379. Epub 2016 Mar 28. PY - 2016 SN - 0803-5253 SP - e232-6 ST - The prevalence of functional gastrointestinal disorders in children in Panama: a school-based study T2 - Acta Paediatr TI - The prevalence of functional gastrointestinal disorders in children in Panama: a school-based study VL - 105 ID - 3795 ER - TY - JOUR AB - OBJECTIVES: This study investigated the incidence and risk factors of chronic daily headache (CDH) and its major subtypes in young adolescents. METHODS: A field cohort of 3342 adolescents aged 13 to 14 was established in 3 middle schools in Taitung, Taiwan, from 2005 to 2007. Participants without CDH at baseline were annually followed up for 1 to 2 years using the same questionnaires, including the Adolescent Depression Inventory and Pediatric Migraine Disability Assessment. The neurologists made the headache diagnoses based on clinical interviews and headache diaries. The person-time incidence rates and risk factors of incident CDH and its subtypes (ie, chronic migraine [CM] and chronic tension-type headache [CTTH]) were calculated by using Cox proportional hazards models. RESULTS: The cohort completed 5586 person-years (PYs) of follow-up. Sixty-three subjects (21 boys/42 girls) developed incident CDH with an incidence rate of 1.13 per 100 PYs, including 37 with CM (0.66 per 100 PYs) and 22 with CTTH (0.39 per 100 PYs). Thirty-three subjects (52%) had a baseline diagnosis of migraine. The independent risk factors for incident CDH included female gender, acute family financial distress, obesity, higher headache frequency, and a baseline diagnosis of migraine. A higher headache frequency was the only identical risk factor for CDH, CM, and CTTH. A baseline diagnosis of migraine and obesity were significant predictors for both CM and CDH. Female gender was a significant predictor for both CTTH and CDH. CONCLUSIONS: Incident CDH was common in young adolescents. Some risk factors for incident CM and CTTH were different. AU - Lu, Shiang-Ru AU - Fuh, Jong-Ling AU - Wang, Shuu-Jiun AU - Juang, Kai-Dih AU - Chen, Shih-Pin AU - Liao, Yi-Chu AU - Wang, Yen-Feng DA - 2013/07// DO - 10.1542/peds.2012-1909 DP - PubMed IS - 1 J2 - Pediatrics KW - adolescence Adolescent Age Factors Cohort Studies Cross-Sectional Studies Depressive Disorder Disability Evaluation Female Follow-Up Studies Headache Disorders Humans incidence Male Migraine Disorders migraine headache Neurologic Examination risk factors Sex Factors Taiwan tension-type headache LA - eng PY - 2013 SN - 1098-4275 SP - e9-e16 ST - Incidence and risk factors of chronic daily headache in young adolescents T2 - Pediatrics TI - Incidence and risk factors of chronic daily headache in young adolescents: a school cohort study UR - http://www.ncbi.nlm.nih.gov/pubmed/23776112 VL - 132 ID - 58 ER - TY - JOUR AB - To estimate the lifetime migraine prevalence in school adolescents aged 13-15 in Taiwan, we conducted a self-administered questionnaire survey in four sampled public junior high schools. Migraine was diagnosed according to the diagnostic criteria of the International Headache Society. A total of 4064 students (1983 boys, 2081 girls) completed the questionnaire (response rate 91.6%). The lifetime prevalence of migraine was 6.8%. It was significantly higher in girls than boys (7.8% vs. 5.7%) and increased with age in both sexes. Students with migraine were more likely to be absent from school because of their headaches than those with non-migraine headaches (30% vs. 14%, odds ratio (OR) 2.7). They were also more likely to use painkillers for their headaches than their non-migraine headache peers (72% vs. 40%, OR 4.0). These results suggest that migraine is a common disorder of adolescents in Taiwan and its impact on the quality of life can not be ignored. AD - Neurological Institute, Taipei Veterans General Hospital and Department of Neurology, National Yang-Ming University School of Medicine, Taiwan. AN - 11037745 AU - Lu, S. R. AU - Fuh, J. L. AU - Juang, K. D. AU - Wang, S. J. DA - Jun DO - 10.1046/j.1468-2982.2000.00076.x DP - NLM ET - 2000/10/19 IS - 5 KW - Absenteeism Adolescent Age Distribution Analgesics/administration & dosage/therapeutic use Headache/drug therapy/epidemiology Health Surveys Humans Menstruation Migraine Disorders/drug therapy/*epidemiology Prevalence Students/*statistics & numerical data Surveys and Questionnaires Taiwan/epidemiology LA - eng N1 - Lu, S R Fuh, J L Juang, K D Wang, S J Journal Article Research Support, Non-U.S. Gov't England Cephalalgia. 2000 Jun;20(5):479-85. doi: 10.1046/j.1468-2982.2000.00076.x. PY - 2000 SN - 0333-1024 (Print) 0333-1024 SP - 479-85 ST - Migraine prevalence in adolescents aged 13-15: a student population-based study in Taiwan T2 - Cephalalgia TI - Migraine prevalence in adolescents aged 13-15: a student population-based study in Taiwan VL - 20 ID - 3454 ER - TY - JOUR AB - The aims of this study were to examine the prevalence, co-occurrence, and psychosocial determinants of self-perceived headache, abdominal pain, and sleep problems among adolescents. The adolescents from two cities in Finland (n = 2,215, 90.9% of the target population) attending 7th and 9th grade (age range 13-18 years) participated in the cross-sectional survey inquiring about frequency of headache, abdominal pain, sleep problems, and psychosocial difficulties. The 6-month prevalence of weekly headache was 13%, abdominal pain 6%, and sleep problems 27%. All three symptoms were strongly associated with each other. Of the adolescents suffering from one symptom, 32% reported one co-occurring symptom and 17% two co-occurring symptoms. In the multivariate analysis, female gender, experience of psychological difficulties, emotional symptoms, smoking, victimization, and feeling not cared about by teachers were independently associated with all the individual symptoms, as well as an increasing number of symptoms. Sleep problems were associated with older age and peer and alcohol problems. Abdominal pain was associated with conduct problems, and both headache and abdominal pain were linked with immigration background. An increasing number of symptoms was associated with older age, having a chronic illness, and conduct and alcohol problems. Adolescents' headache, abdominal pain and sleep problems were common and often co-occurred. An increasing frequency of each symptom and number of symptoms were associated with psychosocial factors in a similar way. Screening for psychiatric symptoms, substance use, victimization and difficulties with teachers should be included in the assessment of adolescents who suffer from recurrent headache, abdominal pain or sleep problems. AN - WOS:000305246500002 AU - Luntamo, T. AU - Sourander, A. AU - Rihko, M. AU - Aromaa, M. AU - Helenius, H. AU - Koskelainen, M. AU - McGrath, P. J. DA - Jun DO - 10.1007/s00787-012-0261-1 IS - 6 N1 - Luntamo, Terhi Sourander, Andre Rihko, Maria Aromaa, Minna Helenius, Hans Koskelainen, Merja McGrath, Patrick J. McGrath, Patrick/0000-0002-9568-2571; Sourander, Andre/0000-0003-0361-7244 PY - 2012 SN - 1018-8827 SP - 301-313 ST - Psychosocial determinants of headache, abdominal pain, and sleep problems in a community sample of Finnish adolescents T2 - European Child & Adolescent Psychiatry TI - Psychosocial determinants of headache, abdominal pain, and sleep problems in a community sample of Finnish adolescents UR - ://WOS:000305246500002 VL - 21 ID - 2435 ER - TY - JOUR AB - Background: The existing knowledge about long-term psychosocial consequences of childhood pain is scarce. The current study investigated childhood pain symptoms as potentia risk factors for antidepressant use in adolescence and early adulthood. Methods: A representative sample of eight-year-old children (n = 6017) and their parents were asked about the prevalence of the child's headache, abdominal pain, and unspecified pails symptoms. The associations with antidepressant purchases by age 24, based on the nationwide prescription register, were analyzed separately for each symptom and each reporter. Sex, parental educational level, and child-, parent- and teacher-reported child's psychiatric symptoms at baseline were included as confounding variables. Results: In the sex-adjusted model, the child's own report of headache and other pains, and the parents' report of their child's abdominal pain, predicted antidepressant purchases. When confounding variables were included in the final model, only the child's own report of headache predicted antidepressant use with a dose-response relationship. The hazard ratios and 95% confidence intervals for frequent and for almost daily headache were 1.6 (1.3-2.0) and 2.1 (1.5-2.9), respectively, in the sex-adjusted model, and 1.5 (1.2-1.8) and 1.7 (1.2-2.5) in the final model. Limitations: The assessment of each pain symptom was based on one question for each reporter. The specific indications for the described medication could not be defined. Conclusions: Health care professionals should also ask children themselves about the pain symptoms. They should be aware that children with pain are at increased risk of suffering later from conditions that require antidepressant treatment. (C) 2012 Elsevier B.V. All rights reserved. AN - WOS:000302976100021 AU - Luntamo, T. AU - Sourander, A. AU - Sillanmaki, L. AU - Gyllenberg, D. AU - Aromaa, M. AU - Kumpulainen, K. AU - Moilanen, I. AU - Almqvist, F. AU - Tamminen, T. AU - Piha, J. DA - Apr DO - 10.1016/j.jad.2012.01.003 IS - 1-2 N1 - Luntamo, Terhi Sourander, Andre Sillanmaki, Lauri Gyllenberg, David Aromaa, Minna Kumpulainen, Kirsti Moilanen, Irma Almqvist, Fredrik Tamminen, Tuula Piha, Jorma Sourander, Andre/0000-0003-0361-7244 1573-2517 PY - 2012 SN - 0165-0327 SP - 153-159 ST - Pain at age eight as a predictor of antidepressant medication use by age 24: Findings from the Finnish nationwide 1981 birth cohort study T2 - Journal of Affective Disorders TI - Pain at age eight as a predictor of antidepressant medication use by age 24: Findings from the Finnish nationwide 1981 birth cohort study UR - ://WOS:000302976100021 VL - 138 ID - 2444 ER - TY - JOUR AB - Pain behaviors provide meaningful information about adolescents in chronic pain, enhancing their verbal report of pain intensity with information about the global pain experience. Caregivers likely consider these expressions when making judgments about their adolescents' medical or emotional needs. Current validated measures of pain behavior target acute or procedural pain and young or non-verbal children, while observation systems may be too cumbersome for clinical practice. The objective of this research was to design and evaluate the Adolescent Pain Behavior Questionnaire (APBQ), a parent-report measure of adolescent (11-19 years) pain expressions. This paper provides preliminary results on reliability and validity of the APBQ. Parent-adolescent dyads (N = 138) seen in a multidisciplinary pain management clinic completed the APBQ and questionnaires assessing pain characteristics, quality of life, functional disability, depressive symptoms, and pain catastrophizing. Principal components analysis of the APBQ supported a single component structure. The final APBQ scale contained 23 items with high internal consistency (alpha = 0.93). No relationship was found between parent-reported pain behaviors and adolescent-reported pain intensity. However, significant correlations were found between parent-reported pain behaviors and parent-and adolescent-reported functional disability, pain catastrophizing, depressive symptoms, and poorer quality of life. The assessment of pain behaviors provides qualitatively different information than solely recording pain intensity and disability. It has clinical utility for use in behavioral treatments seeking to reduce disability, poor coping, and distress. (C) 2010 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved. AN - WOS:000283657300038 AU - Lynch-Jordan, A. M. AU - Kashikar-Zuck, S. AU - Goldschneider, K. R. DA - Dec DO - 10.1016/j.pain.2010.09.025 IS - 3 N1 - Lynch-Jordan, Anne M. Kashikar-Zuck, Susmita Goldschneider, Kenneth R. 1872-6623 PY - 2010 SN - 0304-3959 SP - 834-842 ST - Parent perceptions of adolescent pain expression: The adolescent pain behavior questionnaire T2 - Pain TI - Parent perceptions of adolescent pain expression: The adolescent pain behavior questionnaire UR - ://WOS:000283657300038 VL - 151 ID - 2528 ER - TY - JOUR AB - Importance: Low back pain (LBP) in children and adolescents is a common problem. The differential diagnosis of LBP in this population is broad and different from that seen in the adult population. Most causes of LBP are musculoskeletal and benign in their clinical course. Clinicians should have an understanding of the relevant anatomy and the most commonly encountered etiologic factors of LBP in children and adolescents to provide effective care. Observations: Low back pain is rarely seen in youth before they reach school age. Subsequently, rates of LBP rise until age 18 years, at which age the prevalence of LBP is similar to that in adults. The differential diagnosis of LBP in this population is broad, and individual etiologic factors are most often associated with musculoskeletal overuse or trauma. Sinister etiologic factors are rare. The patient's history and physical examination are the foundation of evaluating a child with LBP. The indication for and timing of specific imaging or other studies will vary depending on the etiologic factor of concern. Most treatment of LBP in this population is centered on relative rest, rehabilitation, and identification of predisposing risk factors. Pharmacologic treatment may be used but is typically a brief course. Orthopedic, rheumatologic, and other subspecialty referrals may be considered when indicated, but most of these patients can be managed by a general pediatrician with a good understanding of the principles described in this article. Conclusions and Relevance: Low back pain in children and adolescents is a common problem. It is most often nonspecific, musculoskeletal, and self-limiting. Pediatricians should recognize the importance of a proper history, physical examination, and general knowledge of the lumbar spine and pelvic anatomy relevant to the child in their evaluation with this presenting symptom. AU - MacDonald, James AU - Stuart, Emily AU - Rodenberg, Richard DA - 2017/03/01/ DO - 10.1001/jamapediatrics.2016.3334 DP - PubMed IS - 3 J2 - JAMA Pediatr KW - Adolescent Child Diagnosis, Differential Female Humans Low Back Pain Lumbar Vertebrae Male Musculoskeletal Pain Prevalence Risk Factors LA - eng PY - 2017 SN - 2168-6211 SP - 280-287 ST - Musculoskeletal Low Back Pain in School-aged Children T2 - JAMA pediatrics TI - Musculoskeletal Low Back Pain in School-aged Children: A Review UR - http://www.ncbi.nlm.nih.gov/pubmed/28135365 VL - 171 ID - 75 ER - TY - JOUR AB - Background: Shoulder and back pain in school children is associated with wearing heavy backpacks. Such pain may be attributed to the magnitude of the backpack load and the manner by which children distribute the load over their shoulders and back. The purpose of this study is to quantify the pressures under backpack straps of children while they carried a typical range of loads during varying conditions. Methods: Ten healthy children (aged, 12-14 years) wore a backpack loaded at 10%, 20%, and 30% body weight (BW). Backpacks were carried under 2 conditions, low on back or high on back. Pressure sensors (0.1 mm thick) measured pressures beneath the shoulder straps. Results: When walking with the backpack straps over both shoulders, contact pressures were significantly greater in the low-back condition than in the high-back condition (P = 0.004). In addition, when children carried the backpack in the low-back condition, mean pressures (+/- SE) over the right shoulder were as follows: 98 +/- 31, 153 +/- 48, and 170 +/- 54 mm Hg at 10%, 20%, and 30% BW, respectively, which were significantly higher (P < 0.001) than those over the left shoulder (46 +/- 14, 92 +/- 29, and 90 +/- 29 mm Hg, respectively). Perceived pain with the backpack over 1 shoulder was significantly greater (P = 0.002) than that for donning with both shoulders in the low-back condition. Conclusions: Pressures at 10%, 20%, and 30% BW loads on the right or left shoulder, during low-back or high-back conditions, are higher than the pressure thresholds (approximately 30 mm Hg) to occlude skin blood flow. Furthermore, asymmetric and high pressures exerted for extended periods of time may help explain the shoulder and back pain attributed to backpacks. Clinical Relevance: Randomized controlled trial. Grade 1 level of evidence. AN - WOS:000262286200005 AU - Macias, B. R. AU - Murthy, G. AU - Chambers, H. AU - Hargens, A. R. DA - Jul-Aug DO - 10.1097/BPO.0b013e31817d8143 IS - 5 N1 - Macias, Brandon R. Murthy, Gita Chambers, Henry Hargens, Alan R. 1539-2570 PY - 2008 SN - 0271-6798 SP - 512-517 ST - Asymmetric Loads and Pain Associated With Backpack Carrying by Children T2 - Journal of Pediatric Orthopaedics TI - Asymmetric Loads and Pain Associated With Backpack Carrying by Children UR - ://WOS:000262286200005 VL - 28 ID - 2643 ER - TY - JOUR AB - Chronic daily headache (CDH) occurs in 1-2% of children and adolescents. It can evolve from either episodic tension-type headache or episodic migraine, or can appear with no previous headache history. As with other primary headache disorders, treatment is based on the level of disability. There are children and adolescents who cope well, but there are others who are markedly disabled by their chronic headaches. As in adults, children and adolescents with CDH are at risk for medication overuse. CDH is a diagnosis of exclusion, based on a thorough history, normal physical examination, and negative neuroimaging findings. Along with the chronic headaches, children with this condition may have co-morbid sleep problems, autonomic dysfunction, anxiety, and/or depression. Principles of treatment include identifying migrainous components, stopping medication overuse, stressing normalcy, using rational pharmacotherapy, and addressing co-morbid conditions. Successful outcomes often involve identifying an appropriate headache preventative, reintegration into school, and family participation in resetting realistic expectations. AD - Child and Adolescent Neurology, Mayo Clinic, Rochester, Minnesota 55905, USA. Mack.Kenneth@mayo.edu AN - 18162005 AU - Mack, K. J. AU - Gladstein, J. DO - 10.2165/00148581-200810010-00003 DP - NLM ET - 2007/12/29 IS - 1 KW - Adolescent Child Headache Disorders/*diagnosis/*drug therapy Humans Treatment Outcome LA - eng N1 - Mack, Kenneth J Gladstein, Jack Journal Article Review Switzerland Paediatr Drugs. 2008;10(1):23-9. doi: 10.2165/00148581-200810010-00003. PY - 2008 SN - 1174-5878 (Print) 1174-5878 SP - 23-9 ST - Management of chronic daily headache in children and adolescents T2 - Paediatr Drugs TI - Management of chronic daily headache in children and adolescents VL - 10 ID - 3068 ER - TY - JOUR AB - Context.-The common cold is one of the most frequently occurring illnesses and is responsible for substantial morbidity and economic loss. Biochemical evidence suggests that zinc may be an effective treatment, and zinc gluconate glycine (ZGG) lozenges have been shown to reduce the duration of cold symptoms in adults. Objective.-To determine the efficacy of ZGG treatment of colds in children and adolescents. Design.-A randomized, double-masked, placebo-controlled study. Setting.-Two suburban school districts in Cleveland, Ohio. Patients.-A total of 249 students in grades 1 through 12 were enrolled within the first 24 hours of experiencing at least 2 of 9 symptoms of the common cold. Intervention.-Zinc lozenges, 10 mg, orally dissolved, 5 times a day (in grades 1-6) or 6 times a day (in grades 7-12), Main Outcome Measures.-Time to resolution of cold symptoms based on subjective daily symptom scores for cough, headache, hoarseness, muscle ache, nasal congestion, nasal drainage, scratchy throat, sore throat, and sneezing. Results.-Time to resolution of all cold symptoms did not differ significantly between students receiving zinc (n = 124) and those receiving placebo (n = 125) (median, 9 days; 95% confidence interval [CI], 8-9 days; median, 9 days, 95% CI, 7-10 days, respectively; P=.71). There were no significant differences in the time to resolution of any of the 9 symptoms studied. Compared with controls, more students in the zinc group reported adverse effects (88.6% vs 79.8%; P=.06); bad taste (60.2% vs 37.9%; P=.001); nausea (29.3% vs 16.1%; P=.01); mouth, tongue, or throat discomfort (36.6% vs 24.2%; P=.03); and diarrhea (10.6% vs 4.0%; P=.05). Conclusions.-In this community-based, randomized controlled trial, ZGG lozenges were not effective in treating cold symptoms in children and adolescents. Further studies with virologic testing are needed to clarify what role, if any, zinc may play in treating cold symptoms. AN - WOS:000074252100032 AU - Macknin, M. L. AU - Piedmonte, M. AU - Calendine, C. AU - Janosky, J. AU - Wald, E. DA - Jun DO - 10.1001/jama.279.24.1962 IS - 24 N1 - Macknin, ML Piedmonte, M Calendine, C Janosky, J Wald, E PY - 1998 SN - 0098-7484 SP - 1962-1967 ST - Zinc gluconate lozenges for treating the common cold in children - A randomized controlled trial T2 - Jama-Journal of the American Medical Association TI - Zinc gluconate lozenges for treating the common cold in children - A randomized controlled trial UR - ://WOS:000074252100032 VL - 279 ID - 2894 ER - TY - JOUR AB - There has been growing recognition of menstrual hygiene management (MHM) as a significant public health issue. However, research has predominately focused on the experiences of adolescent girls in school settings. The purpose of this research is to examine detailed accounts of menstruation for women in rural Odisha, India at various life stages with a view toward improving international monitoring of MHM. Focus group discussions and in-depth interviews were conducted to understand women's experiences of menstruation across four life stages (unmarried women, recently married women, married women, and older women). Thematic analysis was used to identify menstruation-related challenges and needs. We found women voiced needs that aligned with those captured by the WHO/UNICEF Joint Monitoring Programme for Water Supply, Sanitation and Hygiene (JMP) definition for MHM: access to clean materials, privacy for changing materials, soap and water for bathing, and disposal facilities for materials. However, we also found women require materials that are not only clean but comfortable and reliable; soap and water for more than bathing; privacy for the full spectrum of menstruation-related practices, not just when changing; and disposal facilities that are private and safe, not just accessible. Additionally, we identified needs that extend beyond the existing definition: pain management, social support, and an enabling sociocultural environment. Overall, women representing all life stages discussed menstruation challenges, including bathing, pain, and washing, drying, and storing cloth materials. Cloth management challenges were most acute for unmarried and recently married women, who were concerned that practices could reveal their menstrual status and harm their reputations, thus informing their preference for disposable materials, if attainable. We propose a revised definition of adequate MHM for this population that more comprehensively captures their needs. This definition may also prove useful for other populations, future research, creating measures of assessment, and guiding interventions and program priorities. AN - WOS:000484987900024 AU - MacRae, E. R. AU - Clasen, T. AU - Dasmohapatra, M. AU - Caruso, B. A. C7 - e0220114 DA - Aug DO - 10.1371/journal.pone.0220114 IS - 8 N1 - MacRae, Elizabeth R. Clasen, Thomas Dasmohapatra, Munmun Caruso, Bethany A. Caruso, Bethany/0000-0001-9738-9857 PY - 2019 SN - 1932-6203 ST - 'It's like a burden on the head': Redefining adequate menstrual hygiene management throughout women's varied life stages in Odisha, India T2 - Plos One TI - 'It's like a burden on the head': Redefining adequate menstrual hygiene management throughout women's varied life stages in Odisha, India UR - ://WOS:000484987900024 VL - 14 ID - 1890 ER - TY - JOUR AB - The purpose of this study was to conduct a survey examining the impact of inflammatory bowel disease (IBD) on patients' and their caregivers' daily activities. Questionnaires were distributed to patients registered in the APDI (Portuguese Association for IBD) database and their respective caregivers in 2007. Of 422 patient respondents, 251 had Crohn's disease (CD) and 171 had ulcerative colitis (UC), with the majority of patients being women (58.1%) and aged over 40 years (37.4%). The number of disease flares experienced by IBD patients was slightly higher for patients with CD than for patients with UC (2.64 vs. 2.34), and surgery was more often required in CD patients as compared to UC patients (42.4 vs. 7%). Sixty percent (60%) of patients reported having no problems with mobility, daily activities, or personal hygiene; however, over half of all patients experienced some pain and anxiety. Adult patients and children and adolescents respectively experienced time off work or school due to their disease but caregivers were not affected in this regard. The caregivers life (N=324) was affected by anxiety, with the major concern reported as the risk of the patient developing cancer. Both IBD patients and caregivers thought that the provision of information on new drugs and contact time with a doctor would have the biggest impact on improving care. The symptoms and complications of IBD have a considerable impact on the lives of patients and their caregivers, and several actions could be taken to improve their care. AD - GEDII--Portuguese Group of Studies of IBD, Porto, Portugal. fm@med.up.pt AN - 19130226 AU - Magro, F. AU - Portela, F. AU - Lago, P. AU - Deus, J. AU - Cotter, J. AU - Cremers, I. AU - Vieira, A. AU - Peixe, P. AU - Caldeira, P. AU - Lopes, H. AU - Gonçalves, R. AU - Reis, J. AU - Cravo, M. AU - Barros, L. AU - Ministro, P. AU - Lurdes Tavares, M. AU - Duarte, A. AU - Campos, M. AU - Carvalho, L. DA - Dec DO - 10.1007/s10620-008-0658-3 DP - NLM ET - 2009/01/09 IS - 12 KW - *Activities of Daily Living Adaptation, Psychological Adult Anxiety/etiology Caregivers/*psychology Colitis, Ulcerative/complications/*psychology/therapy Cost of Illness Crohn Disease/complications/*psychology/therapy Drug Information Services Employment Female Health Knowledge, Attitudes, Practice Health Surveys Humans Hygiene Male Mobility Limitation Pain/psychology Patient Education as Topic Physician-Patient Relations Portugal Quality of Health Care *Quality of Life Registries Surveys and Questionnaires Young Adult LA - eng N1 - 1573-2568 Magro, F Portela, F Lago, P Deus, J Cotter, J Cremers, I Vieira, A Peixe, P Caldeira, P Lopes, H Gonçalves, R Reis, J Cravo, M Barros, L Ministro, P Lurdes Tavares, M Duarte, A Campos, M Carvalho, L Portuguese Study Group of IBD (GEDII) Association of Portuguese Patients with IBD (APDI) Journal Article Research Support, Non-U.S. Gov't United States Dig Dis Sci. 2009 Dec;54(12):2671-9. doi: 10.1007/s10620-008-0658-3. PY - 2009 SN - 0163-2116 SP - 2671-9 ST - Inflammatory bowel disease: a patient's and caregiver's perspective T2 - Dig Dis Sci TI - Inflammatory bowel disease: a patient's and caregiver's perspective VL - 54 ID - 4163 ER - TY - JOUR AB - Discoid meniscus is the commonest anatomical aberration of the knee joint, among rare cases such as bilateral separated lateral meniscus, accessory lateral meniscus, partial deficiency of the lateral meniscus and double-layered lateral meniscus. An 11-year-old girl presented with history of chronic pain in her right knee for the last 6 months. The problem disturbed her involvement in the sport activities at school. Clinical examination revealed a clicking sensation on knee extension with lateral joint line tenderness. Magnetic resonance imaging (MRI) of her right knee showed torn posterior horn of lateral meniscus. Arthroscopy examination revealed a discoid meniscus with absence posterior horn. Posterior horn deficient discoid meniscus is a rare form of a congenital meniscus anomaly. We as clinicians believe that the abnormal shaped meniscus may pose a diagnostic challenge clinically and radiologically. Presentation of this case may be beneficial for orthopaedicians in their daily clinical practice. AD - Department of Orthopaedic and Traumatology, University Kebangsaan Malaysia Medical Centre, Faculty of Medicine, Kuala Lumpur, Malaysia. drkortho@gmail.com AN - 21400986 AU - Maj, M. K. AU - Ar, A. H. AU - Faisal, S. A. AU - Ahmad, J. AU - Das, S. DO - 10.14712/18059694.2016.86 DP - NLM ET - 2010/01/01 IS - 4 KW - Arthralgia/*etiology Arthroscopy Child Chronic Disease Diagnosis, Differential Female Humans *Knee Joint Menisci, Tibial/*abnormalities LA - eng N1 - Maj, M Kamal Ar, Abdul Halim Faisal, Syed A Ahmad, Johan Das, Srijit Case Reports Journal Article Czech Republic Acta Medica (Hradec Kralove). 2010;53(4):247-9. doi: 10.14712/18059694.2016.86. PY - 2010 SN - 1211-4286 (Print) 1211-4286 SP - 247-9 ST - An 11-year-old girl presenting with chronic knee pain: a case report with diagnostic dilemma T2 - Acta Medica (Hradec Kralove) TI - An 11-year-old girl presenting with chronic knee pain: a case report with diagnostic dilemma VL - 53 ID - 3579 ER - TY - JOUR AB - BACKGROUND: Despite its increasing clinical significance and diagnostic challenges, little is known about functional abdominal pain disorders (FAPDs) in Central-Eastern Europe. In this paper, the prevalence and potential sociodemographic correlates of FAPDs among Hungarian adolescents are explored. METHODS: A cross-sectional, nationwide, questionnaire study in a representative sample of 657 adolescents has been conducted. With a response rate of 80.2%, 522/527 (99.1%) questionnaires were eligible for data analysis (N = 267, 51.1% girls, mean age 14.8, SD 2.4 years). The questionnaire included sociodemographic variables (age, sex, place of residence, marital status of the parents, family income, religion, educational level of parents), questions regarding self-reported specific learning disorders and the Questionnaire for Paediatric Gastrointestinal Symptoms Rome ΙΙΙ Edition. RESULTS: The prevalence of FAPDs was 11.9% (N = 62). FAPDs were significantly associated with female sex. Living in a county town showed a negative correlation with FAPD. Adolescents with self-reported arithmetic learning disorders had an 8.7-fold likelihood of FAPD (OR, 8.7; 95% CI (3.5-21.9). Adolescent girls reported pain in all subtypes of FAPDs more frequently than adolescent boys except functional abdominal pain syndrome. The most prevalent FAPD was abdominal migraine (N = 32, 6.1%), followed by irritable bowel syndrome (N = 24, 4.6%). CONCLUSIONS: The prevalence of FAPDs in Hungary is similar to that reported worldwide, however, contrary to international data, abdominal migraine is the most frequently encountered FAPD in Hungary. In addition to well-known correlates of FAPDs, such as female sex and place of residence, arithmetic learning disorders have also been identified as correlating with the prevalence of FAPDs. Our results suggest culture-specific differences in the distribution of FAPDs, and confirm the significance of school performance indicators such as specific learning disorders as a correlate of FAPDs. AD - Károly Rácz School of PhD Studies, Semmelweis University, Üllői str. 26., Budapest, H-1085, Hungary. major.janos@phd.semmelweis-univ.hu. HRC Bethesda Children's Hospital, Bethesda str. 3., Budapest, H-1146, Hungary. major.janos@phd.semmelweis-univ.hu. Faculty of Health and Public Services, Health Services Management Training Centre, Semmelweis University, Kútvölgyi str. 2., Budapest, H-1125, Hungary. AN - 32505201 AU - Major, J. AU - Ádám, S. C2 - PMC7275532 DA - Jun 6 DO - 10.1186/s12887-020-02167-w DP - NLM ET - 2020/06/09 IS - 1 KW - Abdominal Pain/epidemiology/etiology Adolescent Child Cross-Sectional Studies Europe Europe, Eastern Female Humans Hungary/epidemiology Male Prevalence Risk Factors Self Report *Specific Learning Disorder Surveys and Questionnaires *Abdominal pain *Adolescents *Chronic pain *Epidemiology *Irritable bowel syndrome LA - eng N1 - 1471-2431 Major, János Orcid: 0000-0002-6375-5756 Ádám, Szilvia Journal Article Research Support, Non-U.S. Gov't BMC Pediatr. 2020 Jun 6;20(1):281. doi: 10.1186/s12887-020-02167-w. PY - 2020 SN - 1471-2431 SP - 281 ST - Self-reported specific learning disorders and risk factors among Hungarian adolescents with functional abdominal pain disorders: a cross sectional study T2 - BMC Pediatr TI - Self-reported specific learning disorders and risk factors among Hungarian adolescents with functional abdominal pain disorders: a cross sectional study VL - 20 ID - 3781 ER - TY - JOUR AB - The study examined the psychosocial adaptation problems and short-term outcome of children with functional somatic complaints. Thirty-six children (mean age = 10.5 years, SD = 1.7) with medically unexplained physical symptoms were recruited and were matched in age, sex and socio-economic status to healthy controls. Psychosocial adaptation was measured by the Pre Adolescent Adjustment Scale and the Childhood Psychopathology Measurement Schedule. Results indicated that headaches, abdominal pain, chest pain, general body ache and hyperventilation were some of the common functional somatic symptoms reported. Forty-four percent of the children reported multiple somatic symptoms, though none of them met the clinical criteria for somatization disorder as per DSM IV criteria. Eighty-three percent of the families reported significant psychosocial stressors including family- and school-related problems. Short-term outcome was good and nearly 50% of children improved within 3 to 6 months of psychosocial management. Stepwise multivariate regression analysis revealed that age of the child was the only significant predictor and accounted for 28% of the variance in the short-term outcome (R-2 = .28, F = 12.68, p < 0.001). In addition, children with functional somatic symptoms as compared to controls had significantly lower overall adjustment (p < 0.043) and higher childhood psychopathology scores (p < 0.018). These findings highlight that functional somatic symptoms are common in children and a team approach between a pediatrician and a psychologist is important in the diagnosis and successful management of these children. AN - WOS:000223047800007 AU - Malhi, P. AU - Singhi, P. IS - 2 N1 - Malhi, P Singhi, P PY - 2004 SN - 0039-3320 SP - 163-171 ST - Functional somatic complaints and psychosocial functioning in children and adolescents T2 - Studia Psychologica TI - Functional somatic complaints and psychosocial functioning in children and adolescents UR - ://WOS:000223047800007 VL - 46 ID - 2799 ER - TY - JOUR AB - BACKGROUND: Both mental and physical disorders can result in role limitation, such as 'days out of role', which have an important impact on national productivity losses. This paper analyses data from the South African Stress and Health Study (SASH) on the association of both mental and physical disorders with days out of role. METHODS: Face-to-face interviews were conducted with a representative sample of 4,351 adult South Africans. The World Health Organization's Composite International Diagnostic Interview (WHO-CIDI) was used to assess the presence of 21 mental and physical disorders that were grouped into 10 disorder categories for the analysis: major depressive disorder, any anxiety disorders, any substance abuse disorders, headaches or migraine, arthritis, chronic pain, cardiovascular, respiratory, diabetes and digestive disorders. Multiple regression techniques were used to explore associations between individual disorders, comorbid conditions, and annual days spent out of role. The estimated societal effects of the disorders [population attributable risk proportion (PARP)] were obtained. RESULTS: The majority of respondents who reported a mental or physical disorder also reported another disorder (62.98 %). The average number of disorders reported by respondents who had at least one disorder was 2.3. Overall 12.4 % of respondents reported any days out of role due to mental or physical disorder. Anxiety disorders and depression were associated with highest days out of role (28.2 and 27.2, respectively) followed closely by arthritis and pain (24.7 and 21.7, respectively). Any mental disorder was associated with 23.6 days out of role, while any physical disorder was associated with 15.5 days out of role. Of the mental disorders, anxiety disorders had the highest PARP in relation to days out of role (9.0 %) followed by depression (4.8 %) and substance disorder (3.3. %). More than one-third (37.6 %) of days out of role are attributable to physical disorders and 16.1 % to mental disorders. CONCLUSIONS: Comorbidity is common in both mental and physical disorders, and both are associated with substantial days out of role in South Africa. These data indicate substantial social and economic loss associated with these conditions, and emphasize the need to integrate health services to include common mental disorders in all basic packages of care and to assess for and manage comorbid conditions. AD - Alan J Flisher Centre for Public Mental Health, Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa, sumaya.mall@gmail.com. AN - 25096982 AU - Mall, S. AU - Lund, C. AU - Vilagut, G. AU - Alonso, J. AU - Williams, D. R. AU - Stein, D. J. C2 - PMC4322217 DA - Mar DO - 10.1007/s00127-014-0941-x DP - NLM ET - 2014/08/07 IS - 3 KW - *Absenteeism Adolescent Adult Aged Aged, 80 and over Chronic Disease/*epidemiology Efficiency Health Surveys Humans Male Mental Disorders/*epidemiology Middle Aged Sick Leave/*statistics & numerical data South Africa Substance-Related Disorders/epidemiology Young Adult LA - eng N1 - 1433-9285 Mall, Sumaya Lund, Crick Vilagut, Gemma Alonso, Jordi Williams, David R Stein, Dan J Journal Article Research Support, Non-U.S. Gov't Soc Psychiatry Psychiatr Epidemiol. 2015 Mar;50(3):461-8. doi: 10.1007/s00127-014-0941-x. Epub 2014 Aug 6. PY - 2015 SN - 0933-7954 (Print) 0933-7954 SP - 461-8 ST - Days out of role due to mental and physical illness in the South African stress and health study T2 - Soc Psychiatry Psychiatr Epidemiol TI - Days out of role due to mental and physical illness in the South African stress and health study VL - 50 ID - 3697 ER - TY - JOUR AB - BACKGROUND: Chronic musculoskeletal pain is common in adolescents, and it has been shown that adolescents with pain may become young adults with pain. Pain often coincides with psychosomatic symptoms in adults, but little is known about longitudinal associations and predictors of pain in adolescents. The aim was to investigate chronic musculoskeletal pain and its associations with health status, sleeping problems, stress, anxiety, depression, and physical activity in 16-year-old students at baseline, and to identify risk factors using a three-year follow-up. METHODS: This was a longitudinal study of 256 students attending a Swedish upper secondary school. Questionnaires regarding chronic musculoskeletal pain and distribution of pain (mannequin), health status (EQ-5D-3 L), sleeping problems (Uppsala Sleep Inventory), stress symptoms (single-item question), anxiety and depression (Hospital Anxiety and Depression Scale), and physical activity (International Physical Activity Questionnaire) were issued at baseline and follow-up. Student's t-test and chi(2) test were used for descriptive statistics and logistic regression analyses were used to study associations between chronic pain and independent variables. RESULTS: Fifty-two out of 221 students at baseline (23.5%) and 39 out of 154 students at follow-up (25.3%) were categorized as having chronic musculoskeletal pain. Chronic musculoskeletal pain at follow-up was separately associated with reporting of an EQ-5D value below median (OR 4.06, 95% CI 1.83-9.01), severe sleeping problems (OR 3.63, 95% CI 1.69-7.82), and possible anxiety (OR 4.19, 95% CI 1.74-10.11) or probable anxiety (OR 3.82, 95% CI 1.17-12.48) at baseline. Similar results were found for associations between chronic musculoskeletal pain and independent variables at baseline. In multiple logistic regression analysis, chronic musculoskeletal pain at baseline was a predictor of chronic musculoskeletal pain at follow-up (OR 2.99, 95% CI 1.09-8.24, R(2) = 0.240). CONCLUSION: Chronic musculoskeletal pain at baseline was the most important predictor for reporting chronic musculoskeletal pain at the three-year follow-up, but a worse health status, severe sleeping problems, and anxiety also predicted persistence or development of chronic musculoskeletal pain over time. Interventions should be introduced early on by the school health services to promote student health. AD - The Rydberg Laboratory for Applied Sciences, Halmstad University, Box 823, SE-301 18, Halmstad, Sweden. julia.malmborg@hh.se. Spenshult Research and Development Center, Bäckagårdsvägen 47, SE-302 74, Halmstad, Sweden. julia.malmborg@hh.se. Department of Regional Health Research, University of Southern Denmark, Winsløvsparken 19.3, DK-5000, Odense, Denmark. Danish Hospital for Rheumatic Diseases, University Hospital of Southern Denmark, Engelshøjgade 9A, DK-6400, Sønderborg, Denmark. Department of Clinical Sciences Lund, Section of Rheumatology, Lund University, Box 117, SE-221 00, Lund, Sweden. The Rydberg Laboratory for Applied Sciences, Halmstad University, Box 823, SE-301 18, Halmstad, Sweden. Spenshult Research and Development Center, Bäckagårdsvägen 47, SE-302 74, Halmstad, Sweden. Primary Health Care Unit, Department of Public Health and Community Medicine, Institute of Medicine, The Sahlgrenska Academy, University of Gothenburg, Box 454, SE-405 30, Gothenburg, Sweden. AN - 31771551 AU - Malmborg, J. S. AU - Bremander, A. AU - Olsson, M. C. AU - Bergman, A. C. AU - Brorsson, A. S. AU - Bergman, S. C2 - PMC6880415 DA - Nov 27 DO - 10.1186/s12889-019-7955-y DP - NLM ET - 2019/11/28 IS - 1 KW - Adolescent Anxiety/*epidemiology Chronic Pain/epidemiology/*psychology Female Follow-Up Studies Humans Longitudinal Studies Male Musculoskeletal Pain/epidemiology/*psychology Risk Factors Sleep Wake Disorders/*epidemiology Students/*psychology/statistics & numerical data Surveys and Questionnaires Sweden/epidemiology Anxiety Chronic musculoskeletal pain Epidemiology Health status Sleep Student LA - eng N1 - 1471-2458 Malmborg, Julia S Orcid: 0000-0001-9918-461x Bremander, Ann Orcid: 0000-0002-8081-579x Olsson, M Charlotte Orcid: 0000-0002-9337-5113 Bergman, Anna-Carin Brorsson, A Sofia Bergman, Stefan Orcid: 0000-0002-6294-538x HALLAND-469111/Region Halland/ Journal Article BMC Public Health. 2019 Nov 27;19(1):1565. doi: 10.1186/s12889-019-7955-y. PY - 2019 SN - 1471-2458 SP - 1565 ST - Worse health status, sleeping problems, and anxiety in 16-year-old students are associated with chronic musculoskeletal pain at three-year follow-up T2 - BMC Public Health TI - Worse health status, sleeping problems, and anxiety in 16-year-old students are associated with chronic musculoskeletal pain at three-year follow-up VL - 19 ID - 3081 ER - TY - JOUR AB - AIM: To assess the health-related quality of life in cancer patients and the relative and attributable risks for the degree of dissatisfaction related to intrinsic and extrinsic factors. MATERIAL AND METHODS: Our research included 128 cancer patients treated at the Surgical Clinic II of the Iasi Regional Cancer Institute between December 2014 and June 2015. Thus, data were collected by using an inquiry sheet derived from the SF-36 questionnaire, which included closed and open questions about the quality of life, socioemographic data and such risk factors as smoking, alcohol use, related diseases and risk behaviours. Results: The patient sample had a mean age of 60.85 years, 51.6% of them lived in urban areas, were high school graduates, and of low economic status. DISCUSSION: As to the behavioural risk factors we found that over 80% of the patients were non-smokers, did not use alcohol, and were normal weighted. Pain was experienced by 70.7% of the cancer patients and depression affected 74% of the study cases. Patients were asked to self-assess their own health status on a scale of 0 (worst) to 100 (the best health status). CONCLUSIONS: Our study showed a poor health status (mean score 65) in the study cancer patients. The relative and attributable risks for the degree of dissatisfaction related to intrinsic and extrinsic factors were calculated and ranked factors in decreasing order: smoking, depression, pain, alcohol use, male gender, obesity, low income. We found that prolonged'suffering affects the psyche and causes depression and that the patients of low financial status, most of them living in villages, have difficulty in accessing medical care. The obtained data about the quality of life in relation with risk factors are in agreement with the data in the literature. AN - 27483729 AU - Manafu, E. AU - Nemet, C. AU - Jarit, I. DA - Apr-Jun DP - NLM ET - 2016/08/03 IS - 2 KW - Adolescent Adult Aged Aged, 80 and over Alcohol Drinking/epidemiology Chronic Pain/epidemiology/etiology Depression/epidemiology/etiology Female Health Status Humans Male Middle Aged Neoplasms/epidemiology/*psychology Poverty/statistics & numerical data *Quality of Life Retrospective Studies Risk Factors Romania/epidemiology Smoking/epidemiology Surveys and Questionnaires LA - eng N1 - Manafu, Elenis Nemet, Codruţa Jarit, Irna Journal Article Romania Rev Med Chir Soc Med Nat Iasi. 2016 Apr-Jun;120(2):424-8. PY - 2016 SN - 0048-7848 (Print) 0048-7848 SP - 424-8 ST - EPIDEMIOLOGIC RESEARCH REGARDING THE IMPACT OF RISK FACTORS ON HEALTH-RELEATED QUALITY OF LIFE IN CANCER PATIENTS T2 - Rev Med Chir Soc Med Nat Iasi TI - EPIDEMIOLOGIC RESEARCH REGARDING THE IMPACT OF RISK FACTORS ON HEALTH-RELEATED QUALITY OF LIFE IN CANCER PATIENTS VL - 120 ID - 3622 ER - TY - JOUR AB - Basic personality traits and specific behavior characteristics were assess in 39 patients (12 to 15 years old) having chronic tension-type headache. Patients were referred for clinical examination to the Neural-pediatrics Ward of the Department of Pediatrics, Osijek, Croatia. Eysenck Personality Questionnaire - Juniors (EPQ-J), a new Croatian personality Questionnaire of domination, aggression, introversion and ambition (DAIA), were applied for the testing. The scores obtained by patients in personality questionnaires were compared with averages scores normal sample of healthy pupil same ages. Our patients were found to have no signs of emotional instability. Their behavior is prosocial, nonaggressive, and ambitious, aimed at the achievement of superior results at school and life although already quite successful in their studies. Tensions arising from the school setting seem to be important factors triggering tension-type headaches. AN - WOS:000184682500021 AU - Mandic, Z. AU - Baraban, D. AU - Boranic, M. N1 - Mandic, Z Baraban, D Boranic, M Boranic, Milivoj/0000-0003-2780-7165 1 PY - 2003 SN - 0350-6134 SP - 159-166 ST - Chronic tension-type headache in school-aged children - Personality traits and behavior T2 - Collegium Antropologicum TI - Chronic tension-type headache in school-aged children - Personality traits and behavior UR - ://WOS:000184682500021 VL - 27 ID - 2815 ER - TY - JOUR AB - OBJECTIVE: Nociceptive neuronal circuits are formed during embryonic and postnatal times, so insult during these periods may result in long-term alterations to pain circuitry via synaptic plasticity. One possible long-term result of plasticity is central hyperexcitability, which is suspected to be involved in chronic headache. This study aimed to establish whether there is an association between early pain experiences and the experience of migraines in later childhood. METHODS: In a retrospective study, we examined the charts of 280 pediatric migraineurs at the Division of Pediatric Neurology at Robert Wood Johnson Medical School and documented their perinatal history and migraine characteristics. RESULTS: Analysis revealed that there was a significant relationship between patients who had been in the NICU at birth and the type of pain medication prescribed when compared with patients who had not been in the NICU (chi2 test, chi2(2) = 23.304; N = 30250). Findings also suggested that pediatric migraine patients who had been in the NICU at birth had a significantly earlier age of onset of their migraines (chi2 +/- SD = 7.83 +/- 3.23; N = 30) when compared with patients who did not remain in the NICU (chi2 +/- SD = 9.68 +/- 3.57; N = 250; Kolmogorov-Smirnov Test, chi2 = 10.699). CONCLUSION: On the basis of these findings, we speculate that pain experience as a neonate, through neuronal plasticity and resulting central hyperexcitability, can alter the later experience of pain. However, this observational study cannot validate these links. Other potential explanations that work either synergistically or alone include other forms of stimulation and greater parental vigilance that may occur when neonates spend time in the NICU. This study would prompt additional development of a larger prospective study to establish a link between early pain experience and subsequent pain syndromes and also future investigation into the treatment of pain in neonates as a preventive measure for avoiding long-lasting neuronal alterations. AD - Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, USA. AN - 16199683 AU - Maneyapanda, S. B. AU - Venkatasubramanian, A. DA - Oct DO - 10.1542/peds.2005-0454 DP - NLM ET - 2005/10/04 IS - 4 KW - Adolescent Adult Age of Onset Analgesics/therapeutic use Child Child, Preschool Humans Infant, Newborn *Intensive Care, Neonatal Migraine Disorders/drug therapy/*etiology Neuronal Plasticity Pain/*complications Stress, Physiological/*complications LA - eng N1 - 1098-4275 Maneyapanda, Seetha B Venkatasubramanian, Anuradha Journal Article United States Pediatrics. 2005 Oct;116(4):e555-8. doi: 10.1542/peds.2005-0454. PY - 2005 SN - 0031-4005 SP - e555-8 ST - Relationship between significant perinatal events and migraine severity T2 - Pediatrics TI - Relationship between significant perinatal events and migraine severity VL - 116 ID - 3282 ER - TY - JOUR AB - Objective To evaluate the psychometric properties of the Family Impact Module (FIM), a parent self-report measure of health-related quality of life (HRQOL) and family functioning, among parents of youth with chronic pain. Methods Parents (N = 458) completed the FIM (Total Impact, HRQOL, and Family Functioning scales); parents and youth (N = 332) completed measures of pain catastrophizing, pediatric quality of life, and emotional/behavioral functioning. Results The FIM demonstrated strong internal consistency and item-total correlations. All FIM scales were positively associated with pain catastrophizing, functional disability, and emotional/behavioral problems; and inversely related to pediatric quality of life. Mothers reported significantly worse HRQOL than fathers. Mothers and fathers did not differ on reports of Family Functioning. HRQOL and Family Functioning did not differ as a function of pain diagnosis. Conclusion The FIM appears to be a suitable measure of parent self-reported HRQOL and family functioning in pediatric chronic pain. AN - WOS:000292563200004 AU - Mano, K. E. J. AU - Khan, K. A. AU - Ladwig, R. J. AU - Weisman, S. J. DA - Jun DO - 10.1093/jpepsy/jsp099 IS - 5 N1 - Mano, Kristen E. Jastrowski Khan, Kimberly Anderson Ladwig, Renee J. Weisman, Steven J. 1465-735x Si PY - 2011 SN - 0146-8693 SP - 517-527 ST - The Impact of Pediatric Chronic Pain on Parents' Health-Related Quality of Life and Family Functioning: Reliability and Validity of the PedsQL 4.0 Family Impact Module T2 - Journal of Pediatric Psychology TI - The Impact of Pediatric Chronic Pain on Parents' Health-Related Quality of Life and Family Functioning: Reliability and Validity of the PedsQL 4.0 Family Impact Module UR - ://WOS:000292563200004 VL - 36 ID - 2490 ER - TY - JOUR AB - Musculoskeletal pain is an outstanding symptom among the patients of primary health care. However, there are few studies of management and costs of musculoskeletal pain at primary health care level. The aim of this study was to describe the diagnostic investigations, management, referral rate and sick leaves related to visits prompted by musculoskeletal pain as well as to assess their costs. A total of 28 general practitioners (GPs) at 25 randomly selected health centres throughout Finland collected the data for this 4 week study, which covered 1 week from each of the four seasons. All visits, except those occurring after hours, were recorded. Altogether 1123 patients visited GPs because of musculoskeletal pain. Laboratory tests were ordered for 12% and imaging investigations for 24%. A total of 16% of the patients suffering from musculoskeletal pain received a prescription for physiotherapy, and analgesics were prescribed to 61% of them. Physicians referred 7% of the pain patients to specialist care. One out of every four patients was prescribed sick leave. The mean cost of the investigations, therapy, referrals, and sick leaves was as high as 530 EUR per visit, with absenteeism from work constituting two-fifths of the total costs. Musculoskeletal pain is not just a frequent complaint but also has extensive economic consequences for society. Investigations and therapy at the primary health care level play a minor role in the costs as compared with specialist care and sick leaves. AD - Department of Public Health and General Practice, University of Kuopio, Kuopio, PO Box 1627, 70211 Finland. Pekka.Mantyselka@uku.fi AN - 11900474 AU - Mäntyselkä, P. T. AU - Kumpusalo, E. A. AU - Ahonen, R. S. AU - Takala, J. K. DO - 10.1053/eujp.2001.0311 DP - NLM ET - 2002/03/20 IS - 2 KW - Adolescent Adult Aged Aged, 80 and over Analgesics/therapeutic use Child Child, Preschool Female *Health Care Costs Humans Infant Male Middle Aged Musculoskeletal Diseases/diagnosis/*therapy Pain/diagnosis *Pain Management Palliative Care/*economics/methods Physical Therapy Modalities Referral and Consultation Sick Leave LA - eng N1 - Mäntyselkä, Pekka T Kumpusalo, Esko A Ahonen, Riitta S Takala, Jorma K Journal Article Research Support, Non-U.S. Gov't England Eur J Pain. 2002;6(2):141-8. doi: 10.1053/eujp.2001.0311. PY - 2002 SN - 1090-3801 (Print) 1090-3801 SP - 141-8 ST - Direct and indirect costs of managing patients with musculoskeletal pain-challenge for health care T2 - Eur J Pain TI - Direct and indirect costs of managing patients with musculoskeletal pain-challenge for health care VL - 6 ID - 3703 ER - TY - JOUR AB - Objective: School-based educational programs have shown positive changes in health-related behaviors among adolescents. The aim of this study was to analyze the changes in pain-related knowledge among adolescents and in the use of positive responses to their peers' pain behaviors after watching a brief educational video. Methods: One hundred and thirty-five adolescents (mean age=13.27; SD=1.17) participated and provided demographic and pain-related information. They also responded to a pain-related knowledge questionnaire before (T1), after (T2), and 1 month after (T3) watching a brief pain educational video, and to a modified version of the Inventory of Parent/Caregiver Responses to the Children's Pain Experience at T1 and at T3. Results: There was a significant increase in pain knowledge for all participants between T1 and T2 (eta(2)(p)=0.73) and between T1 and T3 (eta(2)(p)=0.62). An increase in responses considered to be positive to peers' pain behaviors (ie, the promotion of well-behaviors and coping responses) 1 month after watching the educational video was also found. Interestingly, these results were not associated with the chronic pain status of the participant. Discussion: The findings showed that a brief and inexpensive educational video-based intervention in schools helps to increase pain-related knowledge and change responses to students with chronic pain. This has the potential to prevent chronic pain and related disability among students, and decrease bullying-like behaviors toward students with chronic pain. AN - WOS:000622346700006 AU - Marti, L. AU - Castarlenas, E. AU - Sole, E. AU - de la Vega, R. AU - Miro, J. DA - Mar DO - 10.1097/ajp.0000000000000906 IS - 3 N1 - Marti, Lorena Castarlenas, Elena Sole, Ester de la Vega, Rocio Miro, Jordi de la Vega, Rocio/I-8281-2019 de la Vega, Rocio/0000-0002-2517-6948 1536-5409 PY - 2021 SN - 0749-8047 SP - 199-205 ST - Video-based Pain Education in Schools A Study With Adolescents T2 - Clinical Journal of Pain TI - Video-based Pain Education in Schools A Study With Adolescents UR - ://WOS:000622346700006 VL - 37 ID - 1754 ER - TY - JOUR AB - Background Between 4% and 25% of school-aged children at some stage complain of recurrent abdominal pain (RAP) of sufficient severity to interfere with their daily lives. When no clear organic cause is found, the children are managed with reassurance and simple measures; a large range of pharmacological interventions have been recommended for use in these children. Objectives To determine the effectiveness of pharmacological interventions for RAP in children of school age. Search methods We searched the Cochrane Central Register of Controlled Trials (CENTRAL), Ovid MEDLINE, Embase, and eight other electronic databases up to June 2016. We also searched two trials registers and contacted researchers of published studies. Selection criteria Randomised controlled trials involving children aged five to 18 years old with RAP or an abdominal pain-related functional gastrointestinal disorder, as defined by the Rome III criteria (Rasquin 2006). The interventions were any pharmacological intervention compared to placebo, no treatment, waiting list, or standard care. The primary outcome measures were pain intensity, pain duration or pain frequency, and improvement in pain. The secondary outcome measures were school performance, social or psychological functioning, and quality of daily life. Data collection and analysis Two review authors independently screened titles, abstracts, and potentially relevant full-text reports for eligible studies. Two review authors extracted data and performed a 'Risk of bias' assessment. We used the GRADE approach to rate the overall quality of the evidence. We deemed a meta-analysis to be not appropriate as the studies were significantly heterogeneous. We have consequently provided a narrative summary of the results. Main results This review included 16 studies with a total of 1024 participants aged between five and 18 years, all of whom were recruited from paediatric outpatient clinics. Studies were conducted in seven countries: seven in the USA, four in Iran, and one each in the UK, Switzerland, Turkey, Sri Lanka, and India. Follow-up ranged from two weeks to four months. The studies examined the following interventions to treat RAP: tricyclic antidepressants, antibiotics, 5-HT4 receptor agonists, antispasmodics, antihistamines, H2 receptor antagonists, serotonin antagonists, selective serotonin re-uptake inhibitors, a dopamine receptor antagonist, and a hormone. Although some single studies reported that treatments were effective, all of these studies were either small or had key methodological weaknesses with a substantial risk of bias. None of these 'positive' results have been reproduced in subsequent studies. We judged the evidence of effectiveness to be of low quality. No adverse effects were reported in these studies. Authors' conclusions There is currently no convincing evidence to support the use of drugs to treat RAP in children. Well-conducted clinical trials are needed to evaluate any possible benefits and risks of pharmacological interventions. In practice, if a clinician chooses to use a drug as a 'therapeutic trial', they and the patient need to be aware that RAP is a fluctuating condition and any 'response' may reflect the natural history of the condition or a placebo effect, rather than drug efficacy. AN - WOS:000400761200040 AU - Martin, A. E. AU - Newlove-Delgado, T. V. AU - Abbott, R. A. AU - Bethel, A. AU - Thompson-Coon, J. AU - Whear, R. AU - Logan, S. C7 - Cd010973 DO - 10.1002/14651858.CD010973.pub2 IS - 3 N1 - Martin, Alice E. Newlove-Delgado, Tamsin V. Abbott, Rebecca A. Bethel, Alison Thompson-Coon, Joanna Whear, Rebecca Logan, Stuart Coon, Jo Thompson/C-7923-2017 Coon, Jo Thompson/0000-0002-5161-0234; Logan, Stuart/0000-0002-9279-261X; Whear, Rebecca/0000-0002-8379-8198; Abbott, Rebecca/0000-0003-4165-4484 1361-6137 PY - 2017 SN - 1469-493X ST - Pharmacological interventions for recurrent abdominal pain in childhood T2 - Cochrane Database of Systematic Reviews TI - Pharmacological interventions for recurrent abdominal pain in childhood UR - ://WOS:000400761200040 ID - 2115 ER - TY - JOUR AB - Epidermolysis Bullosa (EB) is a group of rare genetic disorders resulting in skin fragility and other symptoms. Commissioned by DEBRA International and funded by DEBRA Norway, this evidence-bases guideline provides recommendations to optimise psychosocial wellbeing in EB.An international multidisciplinary panel of social and health care professionals (HCP) and people living with EB was formed. A systematic international literature review was conducted by the panel following the Scottish Intercollegiate Guidelines Network (SIGN) methodology. The resulting papers underwent systematic selection and critique processes. Included papers were allocated to 6 different outcome groups to allow data synthesis and exploration: quality of life, coping, family, wellbeing, access to HCP and pain. Based on the evidence in those papers, recommendations were made for individuals living with EB, family and caregivers and HCP working in the field.Few studies have investigated interventions and which factors lead to better outcomes, but general recommendations can be made. EB is a complex disease impacting enormously on every aspect of psychosocial life. People and families living with EB need access to multidisciplinary support, including psychological guidance, in order to improve quality of life and psychosocial wellbeing. Interventions should stimulate social participation to prevent isolation. People with EB and their families should be able to access a supportive network. HCP should be well supported and educated about the complexity of EB. They should work collaboratively with those around the individual with EB (e.g. schools, employers etc.) to provide psychosocial opportunity and care.Attention should be paid to the psychosocial impact of EB as well as physical needs. Directions for research are indicated. AN - WOS:000471344000004 AU - Martin, K. AU - Geuens, S. AU - Asche, J. K. AU - Bodan, R. AU - Browne, F. AU - Downe, A. AU - Garcia, N. G. AU - Jaega, G. AU - Kennedy, B. AU - Mauritz, P. J. AU - Perez, F. AU - Soon, K. AU - Zmazek, V. AU - Mayre-Chilton, K. M. C7 - 133 DA - Jun DO - 10.1186/s13023-019-1086-5 N1 - Martin, K. Geuens, S. Asche, J. K. Bodan, R. Browne, F. Downe, A. Garcia, N. Garcia Jaega, G. Kennedy, B. Mauritz, P. J. Perez, F. Soon, K. Zmazek, V. Mayre-Chilton, K. M. PY - 2019 SN - 1750-1172 ST - Psychosocial recommendations for the care of children and adults with epidermolysis bullosa and their family: evidence based guidelines T2 - Orphanet Journal of Rare Diseases TI - Psychosocial recommendations for the care of children and adults with epidermolysis bullosa and their family: evidence based guidelines UR - ://WOS:000471344000004 VL - 14 ID - 1908 ER - TY - JOUR AB - INTRODUCTION: Migraine is seen as being a trivial disease, and more so in childhood, but in many cases it has a detrimental effect on the patient's quality of life. PATIENTS AND METHODS: Prospective study. All the patients were evaluated by the same neuropaediatrician and all of them satisfied diagnostic criteria for migraine. 127 children were examined. The mean age was 9.4 years, with an interval of 3-14 years; there were no differences between sexes. 67 males and 60 females. RESULTS: The mean length of time the episodes lasted was 22.5 h. The most frequently observed clinical features were: hemicranial localisation, 44.4%; throbbing, 74.4%; photophobia, 74.8%; phonophobia, 83.5%; nausea-vomiting, 63.5%; and aura, 14.3%; with predominance of acutely intense visual and sensory symptoms (74%), functional repercussions in 87% and absence from school in up to 36.9% of cases. 16% of patients have had episodes of status migrainous. At the time of the visit 46% had several attacks a week; 13.7% once a week; 16.1% fortnightly; 13.7 % monthly; 5.6% every three months; and others, 4.8%. 48.7% of the patients were given preventive treatment, which was wholly effective in 48%, partially effective in 35% and not at all effective in 15.4%. CONCLUSIONS: Migraine in childhood is not a trivial pathology. It is disabling: it interferes with their daily life in 85% of cases, causes them to miss school in almost 40% of patients and nearly 50% of them have several episodes a week. A similar figure required prophylactic treatment that was seen to be very effective. AD - Unidad de Neuropediatría, Servicio de Neurología, Hospital Universitario de Getafe, 28905 Getafe, Madrid, España. gargomig9@auna.com AN - 16736398 AU - Martínez-Menéndez, B. AU - Pinel-González, A. DA - Jun 1-15 DP - NLM ET - 2006/06/01 IS - 11 KW - Adolescent Analgesics/therapeutic use Child Child, Preschool Female Humans Male Migraine Disorders/diagnosis/drug therapy/*physiopathology/prevention & control Prospective Studies *Quality of Life Sickness Impact Profile LA - spa N1 - Martínez-Menéndez, B Pinel-González, A English Abstract Journal Article Spain Rev Neurol. 2006 Jun 1-15;42(11):643-6. OP - La jaqueca en la infancia: una patologia banal? PY - 2006 SN - 0210-0010 (Print) 0210-0010 SP - 643-6 ST - [Migraine in childhood: a trivial condition?] T2 - Rev Neurol TI - [Migraine in childhood: a trivial condition?] VL - 42 ID - 3442 ER - TY - JOUR AB - AIM: To estimate occurrence of non-specific musculoskeletal pain in a wide population sample of Italian adolescents, and to investigate their use of healthcare services (seeking of medical attention, referral for diagnostic tests and treatment use). METHODS: We investigated 7542 high-school adolescents (aged between 12 and 16 years) by a structured questionnaire and consisting of personal data, presence of pain, health provider consulted, referral for diagnostic tests and compliance with the prescribed treatments. RESULTS: In 3399 (45.1%) reported musculoskeletal pain (the most affected sites being the spine and knees), 2525 (74.2%) of whom had sought medical attention. Of the 2525 subjects who had sought healthcare, 1061 (42.0%) had consulted more than one health provider, 2410 (95.4%) had been referred for diagnostic tests, and some form of treatment had been recommended for 2445 (96.8%), but only 1694 (69.2%) had complied with prescribed therapies. The most important factors linked to health seeking behaviour were pain intensity, pain lasting longer than 3 months, injury, interruption to or absence of physical activity and localization in the spine and knee. CONCLUSION: Non-specific musculoskeletal pain is a frequent event in Italian adolescents and that a large number of these subjects consult a healthcare service. AD - Department of Rehabilitation, University of Padova, Padova, Italy. stef.masiero@unipd.it AN - 20219047 AU - Masiero, S. AU - Carraro, E. AU - Sarto, D. AU - Bonaldo, L. AU - Ferraro, C. DA - Aug DO - 10.1111/j.1651-2227.2010.01770.x DP - NLM ET - 2010/03/12 IS - 8 KW - Adolescent Child Female Health Services/*statistics & numerical data Humans Italy/epidemiology Male Musculoskeletal Diseases/epidemiology/*therapy Pain/epidemiology *Pain Management Pain Measurement Patient Acceptance of Health Care/*psychology/statistics & numerical data Prevalence Referral and Consultation/statistics & numerical data Surveys and Questionnaires LA - eng N1 - 1651-2227 Masiero, Stefano Carraro, Elena Sarto, Diego Bonaldo, Lara Ferraro, Claudio Journal Article Research Support, Non-U.S. Gov't Norway Acta Paediatr. 2010 Aug;99(8):1224-8. doi: 10.1111/j.1651-2227.2010.01770.x. Epub 2010 Mar 8. PY - 2010 SN - 0803-5253 SP - 1224-8 ST - Healthcare service use in adolescents with non-specific musculoskeletal pain T2 - Acta Paediatr TI - Healthcare service use in adolescents with non-specific musculoskeletal pain VL - 99 ID - 3704 ER - TY - JOUR AB - Background: Social anxiety disorder, also known as social phobia, is a marked and persistent fear of one or more social or performance situations in which the person is exposed to unfamiliar people or to possible scrutiny by others. It usually begins in mid-adolescence and has a chronic course and interferes in academic, social, family and personal functioning. Recent studies have shown that social anxiety disorder is more prevalent in adults with migraine. Little evidence on this subject is available for the adolescent population. Methods: This study was performed between August 2009 and August 2010; all patients were recruited in schools, pediatric or neuropediatric facilities, and were submitted to a detailed headache questionnaire, which consisted of demographic and clinical data. To evaluate social anxiety, the Social Phobia Inventory was used. Results: A total of 151 subjects were evaluated: 50 had chronic migraine, 50 had episodic migraine and 51 were control subjects. In the chronic migraine group, the mean score in the Social Phobia Inventory was 18.5 +/- 12.4, which was significantly higher than in the episodic migraine group (12.1 +/- 8.1) and in the control group (13.8 +/- 10.8; F2131= 4.8, P= 0.010). The mean score, however, was not significantly different between the control and episodic migraine groups. Conclusions: Chronic migraine is strongly associated with high social anxiety score, regardless of demographic data and pain intensity. The total burden of migraine may be increased with social anxiety disorder comorbidity. AN - WOS:000304470000024 AU - Masruha, M. R. AU - Lin, J. M. AU - Minett, T. S. C. AU - Vitalle, M. S. D. AU - Fisberg, M. AU - Vilanova, L. C. P. AU - Peres, M. F. P. DA - Jun DO - 10.1111/j.1442-200X.2011.03555.x IS - 3 N1 - Masruha, Marcelo R. Lin, Jaime Minett, Thais S. C. Vitalle, Maria Sylvia de S. Fisberg, Mauro Vilanova, Luiz Celso P. Peres, Mario F. P. Peres, Mario/U-6148-2019; Fisberg, Mauro/E-7149-2010; minett, thais s. c./B-8733-2008; Peres, Mario F/B-1660-2010; de Souza Vitalle, Maria Sylvia/K-6196-2012 Peres, Mario/0000-0002-0068-1905; Fisberg, Mauro/0000-0003-2992-3215; minett, thais s. c./0000-0002-3232-9455; de Souza Vitalle, Maria Sylvia/0000-0001-9405-4250 1442-200x PY - 2012 SN - 1328-8067 SP - 393-396 ST - Social anxiety score is high in adolescents with chronic migraine T2 - Pediatrics International TI - Social anxiety score is high in adolescents with chronic migraine UR - ://WOS:000304470000024 VL - 54 ID - 2433 ER - TY - JOUR AB - The aim of this study was to investigate the relationships between goal frustration, coping and well-being in the context of adolescent headache. Firstly, we investigated whether adolescents with weekly. monthly or no headache complaints differed with regard to the importance assigned to their personal goals, experience of goal frustration, coping with goal frustration and well-being. Secondly, the extent to which goal and coping factors contributed to well-being and whether this relationship differed according to the frequency of headache complaints was examined. For this purpose, 1202 adolescents aged 12-18 completed self-report questionnaires in schools. Adolescents were divided into three groups based on their experience of headache: no headache reported (38%); monthly headache (40%); weekly headache (18%). Results show that these groups did not differ with respect to the importance they attach to goals. They did, however, differ according to experience of goal frustration, use of strategies to cope with goal frustration and well-being, although effect sizes were small. After controlling for individual and headache characteristics, frustration of self acceptance and health goals, and the use of self blame, rumination and other blame were consistently related to lower well-being. Moreover, interactions with headache group indicated that for adolescents with weekly headache, greater frustration of school and self acceptance goals and a lower importance assigned to health goals was more detrimental to well-being than for those with no headache complaints. We conclude that frustration to goal pursuit and strategies for coping with this frustration are important factors in adolescent well-being and may offer important targets for intervention. (C) 2008 European Federation of International Association for the Study of Pain Chapters. Published by Elsevier Ltd. All rights reserved. AN - WOS:000272471800013 AU - Massey, E. K. AU - Garnefski, N. AU - Gebhardt, W. A. DA - Oct DO - 10.1016/j.ejpain.2008.11.012 IS - 9 N1 - Massey, Emma K. Garnefski, Nadia Gebhardt, Winifred A. Gebhardt, Winifred A./ABD-1746-2020 PY - 2009 SN - 1090-3801 SP - 977-984 ST - Goal frustration, coping and well-being in the context of adolescent headache: A self-regulation approach T2 - European Journal of Pain TI - Goal frustration, coping and well-being in the context of adolescent headache: A self-regulation approach UR - ://WOS:000272471800013 VL - 13 ID - 2587 ER - TY - JOUR AB - Objective.- To investigate both concurrent and prospective relationships between daily frustration, cognitive coping and coping efficacy on the one hand and daily headache occurrence on the other. Methods.- Eighty-nine adolescents aged 13-21 completed an online daily diary for 3 weeks. Data were analyzed using multilevel modeling. Results.- Daily frustration of goal pursuits was significantly related to both same day and next day headache occurrence. Coping efficacy beliefs were significantly related to lower next day headache occurrence (no same day relationship was found). None of the cognitive coping strategies used in response to daily frustration were related to headache occurrence on the same or next day. Conclusions.- Daily frustration to goal pursuit is suggested to be an important stressor contributing to concurrent and prospective headache occurrence. Furthermore, the extent to which adolescents believe in their ability to cope also appears to influence experience of subsequent headache. Further prospective studies are necessary to confirm these findings and to further unravel the possibly reciprocal relations between these factors. These findings offer useful insights into the dynamic interplay between daily stressful experiences and headache in youths. AN - WOS:000269368300009 AU - Massey, E. K. AU - Garnefski, N. AU - Gebhardt, W. A. AU - van der Leeden, R. DA - Sep DO - 10.1111/j.1526-4610.2009.01492.x IS - 8 N1 - Massey, Emma K. Garnefski, Nadia Gebhardt, Winifred A. van der Leeden, Rien Gebhardt, Winifred A./ABD-1746-2020 PY - 2009 SN - 0017-8748 SP - 1198-1205 ST - Daily Frustration, Cognitive Coping and Coping Efficacy in Adolescent Headache: A Daily Diary Study T2 - Headache TI - Daily Frustration, Cognitive Coping and Coping Efficacy in Adolescent Headache: A Daily Diary Study UR - ://WOS:000269368300009 VL - 49 ID - 2590 ER - TY - JOUR AB - Migraine is common in adolescents. It can significantly reduce quality of life, may contribute to significant school absences, and disrupt social activities. This article will address the clinical presentation, natural history, types, evaluation, diagnosis and prognosis of migraine. Common adolescent lifestyle factors such as stress, irregular mealtimes, and sleep deprivation may exacerbate migraines. Management options are discussed including lifestyle modifications, acute and preventative therapies. Features of chronic daily headache including comorbid conditions, management, and outcome are also addressed. AN - WOS:000213914400003 AU - Matarese, C. A. AU - Mack, K. J. N1 - Matarese, Christine A. Mack, Kenneth J. PY - 2010 SN - 1179-318X SP - 21-30 ST - Management considerations in the treatment of migraine in adolescents T2 - Adolescent Health Medicine and Therapeutics TI - Management considerations in the treatment of migraine in adolescents UR - ://WOS:000213914400003 VL - 1 ID - 2569 ER - TY - JOUR AB - There is controversy as to the genetic contribution to the pathogenesis of temporomandibular disorders (TMD). Several reports reveal a marked familial aggregation in the signs and symptoms of TMD, while others do not. Therefore, our goal was to investigate the hypothesis using a sophisticated research design, which was a well-known genetic survey inter-twin concordance assessment in the symptoms of TMD. This study is the first step to survey TMD symptoms of a twin group in junior and high schools as a preliminary trial. The 63 twins were asked to participate in this study in junior and senior high schools affiliated with the University of Tokyo, Japan, schools which kept ten twins in each grade for the purpose of several genetic survey programs. After excluding incomplete filling out of questionnaire sheets and data from male-female pairs, 43 monozygotic (MZ) (15.3 +/- 1.7 yrs, male/female = 17/26 pairs) and nine dyzygotic (DZ) (15.2 +/- 1.8 yrs, male/female = 6/3 pairs) twins were studied. Outcomes consisted of a prevaliclated 14-item self-administered questionnaire, which assessed proband- and pair-wise concordance levels in the MZ and DZ twins. These results demonstrated that the MZ twins had a higher tendency of inter-twin concordance than DZ twins in terms of jaw pain in wide mouth opening (proband-wise concordance = 66.7% in MZ, 0% in DZ), difficulty in mouth opening (20% in MZ, 0% in DZ) and difficulty in mouth closing (50.0% in MZ, 33.3% in DZ), while there was no significant difference between the MZ and DZ concordance levels in other general health-related and behavior-related items, except toothache. However, the pair-wise concordance rates of jawpain in wide mouth opening and difficulty in mouth opening in the MZ twins were not significantly higher compared to the DZ rate. Possibly, a genetic factor contributed to the pathogenesis of TMD in an adolescent population. The sample size needs to be increased, and there are plans to survey the next sample in the same schools. AN - WOS:000243765600005 AU - Matsuka, Y. AU - Nagamatsu, C. AU - Itoh, S. AU - Tomonari, T. AU - Makki, A. AU - Minakuchi, H. AU - Mackawa, K. AU - Kanyama, M. AU - Kuboki, T. DA - Jan DO - 10.1179/crn.2007.005 IS - 1 N1 - Matsuka, Yoshizo Nagamatsu, Chiyomi Itoh, Shingo Tomonari, Takayuki Makki, Ali Minakuchi, Hajime Mackawa, Kenji Kanyama, Manabu Kuboki, Takuo Kuboki, Takuo/A-5955-2010 Kuboki, Takuo/0000-0003-3756-2835; Matsuka, Yoshizo/0000-0003-1069-2605 2151-0903 PY - 2007 SN - 0886-9634 SP - 23-29 ST - Comparison of inter-twin concordance in symptoms of temporomandibular disorders: A preliminary investigation in an adolescent twin population T2 - Cranio-the Journal of Craniomandibular & Sleep Practice TI - Comparison of inter-twin concordance in symptoms of temporomandibular disorders: A preliminary investigation in an adolescent twin population UR - ://WOS:000243765600005 VL - 25 ID - 2706 ER - TY - JOUR AB - An 11-year-old boy collapsed during morning assembly at his junior high school. The automated external defibrillator detected ventricular fibrillation and provided shock delivery. He was successfully resuscitated and reverted to sinus rhythm. Electrocardiography showed ST-T elevation in the precordial leads. Echocardiography and angiography demonstrated akinesia of the apex and mid-wall of the left ventricle with preserved contraction of the basal segments, which suggested Takotsubo cardiomyopathy. The patient and his family had often eaten uncooked crab, and his father had a past history of infection with Paragonimiasis westermani. The patient had had a persistent cough and chest pain for several weeks. Chest radiograph showed cystic cavities in the left upper lung. Microbiological examination of the sputum demonstrated an egg of P. westermani and immunological assay showed a raised antibody titre to P. westermani. On the12th day of admission, he developed seizures, and magnetic resonance imaging demonstrated cerebral involvement. After the administration of praziquantel for 3 days, the clinical manifestations improved immediately, and echocardiography normalised within 3 weeks. The patient was discharged on the 32nd day + and follow-up was normal. Takotsubo cardiomyopathy following a potentially fatal arrhythmia is a rare cardiac complication associated with pulmonary and central nervous system infection by P. westermani. AN - WOS:000451528400013 AU - Matsuoka, R. AU - Muneuchi, J. AU - Nagatomo, Y. AU - Shimizu, D. AU - Okada, S. AU - Iida, C. AU - Shirouzu, H. AU - Watanabe, M. AU - Takahashi, Y. AU - Maruyama, H. DO - 10.1080/20469047.2017.1371482 IS - 4 N1 - Matsuoka, Ryouhei Muneuchi, Jun Nagatomo, Yusaku Shimizu, Daisuke Okada, Seigo Iida, Chiaki Shirouzu, Hiromitsu Watanabe, Mamie Takahashi, Yasuhiko Maruyama, Haruhiko Okada, Seigo/K-5307-2019 Okada, Seigo/0000-0002-9150-1913 2046-9055 PY - 2018 SN - 2046-9047 SP - 302-307 ST - Takotsubo cardiomyopathy associated with Paragonimiasis westermani T2 - Paediatrics and International Child Health TI - Takotsubo cardiomyopathy associated with Paragonimiasis westermani UR - ://WOS:000451528400013 VL - 38 ID - 2041 ER - TY - JOUR AB - OBJECTIVES: Social deprivation is associated with a higher prevalence of chronic pain in children and an under-representation in specialist paediatric chronic pain programs. Our primary objective was to determine if there was a relationship between social deprivation and paediatric chronic pain referrals in Ireland. Secondary objectives included analysing for differences between deprivation groups in pain characteristics and function that are recorded at first clinic visit. METHODS: Families attending the national paediatric complex pain service in Dublin, Ireland, complete questionnaires on pain characteristics, parental pain catastrophizing, and pain-related disability including sleep quality and school attendance. We retrospectively reviewed records from between February 2016 and November 2019 on 288 patients. Social deprivation was assessed using the Pobal HP Deprivation Index, which is based on data from the Irish national census. RESULTS: Referrals followed a normal distribution across deprivation grades. Children in the disadvantaged group had a longer duration of pain, greater use of screens at bedtime, and longer sleep onset latency. Parents in the disadvantaged group had significantly higher levels of parental pain catastrophizing. CONCLUSIONS: In Ireland, while paediatric chronic pain referrals were normally distributed across deprivation group, the disadvantaged group was different in several ways that may be clinically significant. Further work will be needed to determine the longitudinal relationship between these factors before and after the referral and initial review. Screening for, and targeting, potential risk factors for pain chronicity may be needed to harmonize treatment outcomes in children from socially disadvantaged families. AD - Children's Health Ireland at Crumlin, Dublin, Ireland. Children's Health Ireland at Temple Street, Dublin, Ireland. Discipline of Paediatrics, School of Medicine, Trinity College Dublin, Dublin, Ireland. AN - 34080402 AU - Matthews, E. AU - Muldoon, M. AU - O'Keeffe, N. AU - McCarthy, K. F. DA - Jun 1 DO - 10.1515/sjpain-2021-0031 DP - NLM ET - 2021/06/04 KW - chronic pain paediatric pain pain catastrophizing sleep quality social deprivation LA - eng N1 - 1877-8879 Matthews, Eveline Muldoon, Maeve O'Keeffe, Norma McCarthy, Kevin F Journal Article Germany Scand J Pain. 2021 Jun 1. doi: 10.1515/sjpain-2021-0031. PY - 2021 SN - 1877-8860 ST - Social deprivation and paediatric chronic pain referrals in Ireland: a cross-sectional study T2 - Scand J Pain TI - Social deprivation and paediatric chronic pain referrals in Ireland: a cross-sectional study ID - 4016 ER - TY - JOUR AB - OBJECTIVE: To classify paediatric chronic pain referrals in Ireland using the ICD-11 classification. In addition, differences between primary and secondary pain groups were assessed. METHODS: Retrospective review of complex pain assessment forms completed at the time of initial attendance at paediatric chronic pain clinics in Dublin, Ireland. Patients were classified as having a chronic primary (CPP) or chronic secondary (CSP) pain condition as per ICD-11 classification. Secondary analysis of between-group and within-group differences between primary and secondary pain conditions was undertaken. RESULTS: Of 285 patients coded, 123 patients were designated as having a CPP condition (77% of which were assigned an adjunct parent code) and 162 patients as having a CSP condition (61% of which were assigned an adjunct parent code). Between-group comparisons found that the lowest reported pain scores were higher in CPP than CSP conditions. In the CSP group, there were stronger correlations between parental pain catastrophizing and pain intensity, school attendance, and pain interference with social activities, than in the CPP group. CONCLUSIONS: The majority of children with both CPP and CSP were assigned multiple parent codes. There appears to be a gradient in the differences in biopsychosocial profile between CPP and CSP conditions. Additional field testing of the ICD-11 classification in paediatric chronic pain will be required. AD - Children's Health Ireland at Crumlin, Dublin, Ireland, D12N512. Children's Health Ireland at Temple Street, Dublin, Ireland, D01DX99. Department of Paediatrics, Trinity College Dublin, D02R590. AN - 33769541 AU - Matthews, E. AU - Murray, G. AU - McCarthy, K. DA - Mar 25 DO - 10.1093/pm/pnab116 DP - NLM ET - 2021/03/27 KW - International Classification of Diseases chronic pain diagnostic uncertainty paediatric pain pain catastrophizing primary pain LA - eng N1 - 1526-4637 Matthews, Eveline Murray, Geraldine McCarthy, Kevin Journal Article England Pain Med. 2021 Mar 25:pnab116. doi: 10.1093/pm/pnab116. PY - 2021 SN - 1526-2375 ST - ICD-11 classification of paediatric chronic pain referrals in Ireland with secondary analysis of primary vs. secondary pain conditions T2 - Pain Med TI - ICD-11 classification of paediatric chronic pain referrals in Ireland with secondary analysis of primary vs. secondary pain conditions ID - 4105 ER - TY - JOUR AB - OBJECTIVES: To determine the prevalence of migraine and its association with age, gender, and social class and to find out whether or not the headache and nonheadache characteristics differ between children with migraine, with and without aura, using the diagnostic criteria of the International Headache Society for childhood migraine. DESIGN: Population-based study in two stages comprising an initial screening questionnaire followed by telephone interviews of children with symptoms. SETTING: Eighteen kindergarten and 39 primary and secondary schools in Thessaloniki and its semiurban areas. SUBJECTS: Four thousand children, aged 4 to 15 years, representing a random sample of 5% of schoolchildren in Thessaloniki and its semiurban areas. MAIN OUTCOME MEASURES: (1) The prevalence of migraine, (2) the connection of migraine with social class, (3) differences in the occurrence of individual symptoms between migraine with and without aura. RESULTS: The results of the present study show that migraine prevalence was 6.2% (95% confidence interval [CI], 5.4 to 7.0). The estimated prevalences of migraine with and without aura were 2.8% (95% CI, 2.3 to 3.4) and 3.4% (CI, 2.8 to 4.0), respectively. The prevalence of migraine increased with age and it was found to be almost equal in boys and girls aged 7 to 9 years or younger, but in older age groups the prevalence was higher in girls than in boys. The data showed no evidence that connected migraine with social class. It also showed that except for the aura, the headache (e.g., frequency, duration, location, quality, and severity) and nonheadache (e.g., nausea, vomiting, phonophobia, and photophobia) characteristics were no different between children with migraine, with and without aura. In conclusion, our findings indicate that migraine is a common underdiagnosed cause of severe recurrent headache in children. The findings show that childhood migraine is not connected with social class and varies with age and gender, and that except for the aura, both migraine with and without aura are so similar in their headache and nonheadache clinical characteristics that a common pathogenesis is plausible. AD - Second Paediatric Department, Aristotelian University of Thessaloniki (Greece), AHEPA General Hospital. AN - 11279949 AU - Mavromichalis, I. AU - Anagnostopoulos, D. AU - Metaxas, N. AU - Papanastassiou, E. DA - Nov-Dec DO - 10.1046/j.1526-4610.1999.3910728.x DP - NLM ET - 2001/03/31 IS - 10 KW - Adolescent Child Child, Preschool Female Greece Humans Male Migraine Disorders/*epidemiology/*physiopathology Migraine with Aura/*physiopathology Prevalence Schools LA - eng N1 - Mavromichalis, I Anagnostopoulos, D Metaxas, N Papanastassiou, E Comparative Study Journal Article United States Headache. 1999 Nov-Dec;39(10):728-36. doi: 10.1046/j.1526-4610.1999.3910728.x. PY - 1999 SN - 0017-8748 (Print) 0017-8748 SP - 728-36 ST - Prevalence of migraine in schoolchildren and some clinical comparisons between migraine with and without aura T2 - Headache TI - Prevalence of migraine in schoolchildren and some clinical comparisons between migraine with and without aura VL - 39 ID - 3197 ER - TY - JOUR AB - Objectives: To assess motives for nonmedical use of prescription opioids among US high school seniors and examine associations between motives for nonmedical use and other substance use behaviors. Design: Nationally representative samples of US high school seniors (modal age 18 years) were surveyed during the spring of their senior year via self-administered questionnaires. Setting: Data were collected in public and private high schools. Participants: The sample consisted of 5 cohorts (2002-2006) of 12441 high school seniors. Main Outcome Measures: Self-reports of motives for nonmedical use of prescription opioids and substance use behaviors. Results: More than 1 in every 10 high school seniors reported nonmedical use of prescription opioids and 45% of past-year nonmedical users reported "to relieve physical pain" as an important motivation. The odds of heavy drinking and other drug use were lower among nonmedical users of prescription opioids motivated only by pain relief compared with nonmedical users who reported pain relief and other motives and those who reported non-pain relief motives only. The odds of medical use of prescription opioids were lower among nonmedical users who reported only non-pain relief motives compared with other types of nonmedical users. Conclusions: The findings indicate motives should be considered when working with adolescents who report nonmedical use of prescription opioids. Future efforts are needed to identify adolescents who may need appropriate pain management and those at increased risk for prescription opioid abuse. AN - WOS:000268634600009 AU - McCabe, S. E. AU - Boyd, C. J. AU - Cranford, J. A. AU - Teter, C. J. DA - Aug DO - 10.1001/archpediatrics.2009.120 IS - 8 N1 - McCabe, Sean Esteban Boyd, Carol J. Cranford, James A. Teter, Christian J. Cranford, James A./H-7240-2019 Cranford, James/0000-0003-2068-9282; McCabe, Sean/0000-0002-9622-4652; Boyd, Carol/0000-0003-2651-6614 1538-3628 PY - 2009 SN - 1072-4710 SP - 739-744 ST - Motives for Nonmedical Use of Prescription Opioids Among High School Seniors in the United States Self-treatment and Beyond T2 - Archives of Pediatrics & Adolescent Medicine TI - Motives for Nonmedical Use of Prescription Opioids Among High School Seniors in the United States Self-treatment and Beyond UR - ://WOS:000268634600009 VL - 163 ID - 2594 ER - TY - JOUR AB - Objectives: This study examined the prevalence rates and correlates of nonmedical use of prescription opioid analgesics among U.S. college students in terms of student and college characteristics. Methods: This study analyzed data from a nationally representative sample of 10,904 randomly selected students attending 119 four-year colleges in 2001. Results: The lifetime prevalence of nonmedical prescription opioid use was 12% and the past year prevalence was 7%. Approximately one in every four colleges had a prevalence of 10% or higher for past year nonmedical use of prescription opioids. Multivariate regression analyses indicated nonmedical use was more likely to occur among college students who were white, residents of fraternity and sorority houses, attended more competitive colleges, earned lower grade point averages, and reported higher rates of substance use and other risky behaviors. Conclusions: This study provides evidence that the nonmedical use of prescription opioids represents a problem on college campuses. These findings have important implications for developing prevention efforts and therapeutic strategies aimed at reducing the nonmedical use of prescription opioid analgesics among college students while not hindering necessary medication management for pain. (c) 2004 Elsevier Ltd. All rights reserved. AN - WOS:000228757100014 AU - McCabe, S. E. AU - Teter, C. J. AU - Boyd, C. J. AU - Knight, J. R. AU - Wechsler, H. DA - May DO - 10.1016/j.addbeh.2004.08.024 IS - 4 N1 - McCabe, SE Teter, CJ Boyd, CJ Knight, JR Wechsler, H Duran, Bonnie m/A-3029-2009 Boyd, Carol/0000-0003-2651-6614; McCabe, Sean/0000-0002-9622-4652 1873-6327 PY - 2005 SN - 0306-4603 SP - 789-805 ST - Nonmedical use of prescription opioids among US college students: Prevalence and correlates from a national survey T2 - Addictive Behaviors TI - Nonmedical use of prescription opioids among US college students: Prevalence and correlates from a national survey UR - ://WOS:000228757100014 VL - 30 ID - 2764 ER - TY - JOUR AB - This study examined the motives for medical misuse of prescription opioids among adolescents and assessed differences in motives by demographic characteristics, substance abuse, and diversion behaviors. A survey was conducted in 2011 to 2012 and the sample consisted of 2,964 adolescents (51% female). Thirteen percent reported past-year medical use of prescription opioids. Among those prescribed opioids in the past year (n = 393), 17.9% reported medical misuse (eg, using too much, using to get high, or using to increase alcohol or other drug effects). The most prevalent motives for medical misuse were "to relieve pain" (84.2%) and "to get high" (35.1%). Multivariate analyses indicated that the motives differed by race, and that different motives were associated with different substance abuse and diversion behaviors. The odds of past-year substance abuse among medical misusers motivated by non pain relief were more than 15 times greater than for nonusers (adjusted odds ratio = 15.2, 95% CI = 6.4-36.2, P <.001). No such differences existed between nonusers and appropriate medical users, or between nonusers and medical misusers motivated by pain relief only. These findings improve our understanding of opioid medication misuse among adolescents and indicate the need for enhanced education about appropriate medical use, pain management, and patient communication with prescribers. Perspective: This article represents the first investigation to examine the motives associated with medical misuse of prescription opioids among adolescents. The results indicate that the majority of medical misuse is associated with pain relief. This information could be used to develop strategies to reduce opioid medication misuse among adolescents. (C) 2013 by the American Pain Society AN - WOS:000325782400021 AU - McCabe, S. E. AU - West, B. T. AU - Boyd, C. J. DA - Oct DO - 10.1016/j.jpain.2013.05.004 IS - 10 N1 - McCabe, Sean Esteban West, Brady T. Boyd, Carol J. McCabe, Sean/0000-0002-9622-4652; Boyd, Carol/0000-0003-2651-6614 PY - 2013 SN - 1526-5900 SP - 1208-1216 ST - Motives for Medical Misuse of Prescription Opioids Among Adolescents T2 - Journal of Pain TI - Motives for Medical Misuse of Prescription Opioids Among Adolescents UR - ://WOS:000325782400021 VL - 14 ID - 2344 ER - TY - JOUR AB - Background Mindfulness-based training has been shown to provide benefits for adults with numerous conditions such as cancer, chronic pain, and depression. However, less is known about its impact for young people. Early adolescence (typically 10-14 years) is a time fraught with challenges such as cognitive changes, social, and academic pressures in the form of exams, all of which can provoke anxiety. While there is a lack of effectiveness studies, there is growing interest in the potential for school-based mindfulness programmes to help young people cope with the pressures of modern life. Methods This study outlines a qualitative exploration of a school-based targeted mindfulness course. We interviewed 16 young people who had taken part in a 10-week mindfulness course, and held a focus group with three members of teaching staff who delivered the programme. Interviews and focus groups were analysed using applied thematic analysis. Results While young people felt that they had to take part, once they started the programme they enjoyed it. Young people felt that they learned a range of coping skills, and it had a positive impact on their behaviour. However, the targeted approach of the intervention could lead to young people being stigmatised by their peers. Teaching staff could see the potential benefit of mindfulness courses in schools but felt there were some barriers to be overcome if it were to be implemented in the long term. Conclusions Young people were willing to engage in mindful practice and felt it better equipped them to deal with stressful situations. AN - WOS:000465004300009 AU - McGeechan, G. J. AU - Richardson, C. AU - Wilson, L. AU - Allan, K. AU - Newbury-Birch, D. DA - May DO - 10.1111/camh.12288 IS - 2 N1 - McGeechan, Grant J. Richardson, Catherine Wilson, Lynn Allan, Keith Newbury-Birch, Dorothy McGeechan, Grant James/AAC-7250-2019 McGeechan, Grant James/0000-0002-3994-8507; Newbury-Birch, Dorothy/0000-0003-0065-8649 1475-3588 PY - 2019 SN - 1475-357X SP - 154-160 ST - Qualitative exploration of a targeted school-based mindfulness course in England T2 - Child and Adolescent Mental Health TI - Qualitative exploration of a targeted school-based mindfulness course in England UR - ://WOS:000465004300009 VL - 24 ID - 1928 ER - TY - JOUR AB - I never intended to become a scientist. My career developed on the basis of chance happenings, repeated failure, the willingness to take risks and the acceptance and provision of mentoring. My career has included periods of difficulty and shifted back and forth between academic health centers and universities in Canada. Although I have been amply recognized for my successes, my greatest learning has come from my failures. My greatest satisfaction has been in the development, evaluation and dissemination of interventions. The combination of intellectual stimulation and emotional gratification has meant a rewarding career. AN - WOS:000441243400003 AU - McGrath, P. J. DA - Aug DO - 10.1093/jpepsy/jsy017 IS - 7 N1 - McGrath, Patrick J. 1465-735x PY - 2018 SN - 0146-8693 SP - 716-722 ST - Pioneer Paper: An Accidental Scientist: Chance, Failure, Risk-Taking, and Mentoring T2 - Journal of Pediatric Psychology TI - Pioneer Paper: An Accidental Scientist: Chance, Failure, Risk-Taking, and Mentoring UR - ://WOS:000441243400003 VL - 43 ID - 2000 ER - TY - JOUR AB - Under the auspices of the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT), 26 professionals from academia, governmental agencies, and the pharmaceutical industry participated in a 2-stage Delphi poll and a consensus meeting that identified core outcome domains and measures that should be considered in clinical trials of treatments for acute and chronic pain in children and adolescents. Consensus was refined by consultation with the international pediatric pain community through announcement of our recommendations on the Pediatric Pain List and inviting and incorporating comments from external sources. There was consensus that investigators conducting pediatric acute pain clinical trials should consider assessing outcomes in pain intensity; global judgment of satisfaction with treatment; symptoms and adverse events; physical recovery; emotional response; and economic factors. There was also agreement that investigators conducting pediatric clinical trials in chronic and recurrent pain should consider assessing outcomes in pain intensity; physical functioning; emotional functioning; role functioning; symptoms and adverse events; global judgment of satisfaction with treatment; sleep; and economic factors. Specific measures or measurement strategies were recommended for different age groups for each domain. Perspective: Based on systematic review and consensus of experts, core domains and measures for clinical trials to treat pain in children and adolescents were defined. This will assist in comparison and pooling of data and promote evidence-based treatment, encourage complete reporting of outcomes, simplify the review of proposals and manuscripts, and facilitate clinicians making informed decisions regarding treatment. (C) 2008 by the American Pain Society. AN - WOS:000259172200002 AU - McGrath, P. J. AU - Walco, G. A. AU - Turk, D. C. AU - Dworkin, R. H. AU - Brown, M. T. AU - Davidson, K. AU - Eccleston, C. AU - Finley, G. A. AU - Goldschneider, K. AU - Haverkos, L. AU - Hertz, S. H. AU - Ljungman, G. AU - Palermo, T. AU - Rappaport, B. A. AU - Rhodes, T. AU - Schechter, N. AU - Scott, J. AU - Sethna, N. AU - Svensson, O. K. AU - Stinson, J. AU - von Baeyer, C. L. AU - Walker, L. AU - Weisman, S. AU - White, R. E. AU - Zajicek, A. AU - Zeltzer, L. DA - Sep DO - 10.1016/j.jpain.2008.04.007 IS - 9 N1 - McGrath, Patrick J. Walco, Gary A. Turk, Dennis C. Dworkin, Robert H. Brown, Mark T. Davidson, Karina Eccleston, Christopher Finley, G. Allen Goldschneider, Kenneth Haverkos, Lynne Hertz, Sharon H. Ljungman, Gustaf Palermo, Tonya Rappaport, Bob A. Rhodes, Thomas Schechter, Neil Scott, Jane Sethna, Navil Svensson, Ola K. Stinson, Jennifer von Baeyer, Carl L. Walker, Lynn Weisman, Steven White, Richard E. Zajicek, Anne Zeltzer, Lonnie Finley, Allen/AAD-7583-2020; McGrath, Patrick J/F-4326-2011; Zajicek, Anne/I-3448-2019; Davidson, Karina/AAG-2388-2019 Finley, Allen/0000-0003-4579-7749; Davidson, Karina/0000-0002-9162-477X; McGrath, Patrick/0000-0002-9568-2571; Zajicek, Anne/0000-0001-9113-2874; Eccleston, Christopher/0000-0003-0698-1543; von Baeyer, Carl/0000-0002-6308-1966; Zeltzer, Lonnie/0000-0001-9306-9450; Ljungman, Gustaf/0000-0002-4949-2494 PY - 2008 SN - 1526-5900 SP - 771-783 ST - Core outcome domains and measures for pediatric acute and chronic/recurrent pain clinical trials: PedIMMPACT recommendations T2 - Journal of Pain TI - Core outcome domains and measures for pediatric acute and chronic/recurrent pain clinical trials: PedIMMPACT recommendations UR - ://WOS:000259172200002 VL - 9 ID - 2638 ER - TY - JOUR AB - Purpose The relationship between exposure to abuse and interstitial cystitis/bladder pain syndrome (IC/BPS) is well-documented. However, studies have yet to examine posttraumatic stress disorder (PTSD), which develops following exposure to trauma and worsens health outcomes in chronic pain. We aimed to assess the prevalence and impact of PTSD in patients with IC/BPS, including their relation to genitourinary symptom presentation and widespread pain phenotype. Materials and Methods We recruited 202 participants with chronic pain from an academic medical center and classified 64 individuals as IC/BPS based on validated epidemiological criteria. Participants completed self-reported questionnaires assessing trauma exposure, PTSD symptoms, emotional distress, pain, and urinary symptoms. Wilcoxon rank-sum tests assessed study aims comparing IC/BPS to other chronic pain. Results Although elevated, IC/BPS trauma exposure rates were equivalent to that of other chronic pain conditions in the sample. Despite this equivalence, in comparison, IC/BPS patients had significantly higher rates of PTSD symptoms, with 42% meeting provisional diagnostic criteria for PTSD. Among IC/BPS, those meeting provisional criteria for PTSD had significantly higher incidence of lifetime sexual abuse, childhood trauma, and presentations consistent with the widespread pain phenotype. In IC/BPS, there was no association between PTSD and genitourinary symptoms, but provisional PTSD was associated with more pain, emotional distress, and poorer quality of life. Conclusions We recommend that patients with IC/BPS and widespread pain have ongoing screening and monitoring of PTSD. We recommend using trauma-informed care practices with these patients to increase trust and safety, which could improve treatment compliance and follow-up. AN - WOS:000454511600041 AU - McKernan, L. C. AU - Johnson, B. N. AU - Reynolds, W. S. AU - Williams, D. A. AU - Cheavens, J. S. AU - Dmochowski, R. R. AU - Crofford, L. J. DA - Jan DO - 10.1002/nau.23861 IS - 1 N1 - McKernan, Lindsey C. Johnson, Benjamin N. Reynolds, William S. Williams, David A. Cheavens, Jennifer S. Dmochowski, Roger R. Crofford, Leslie J. Reynolds, William/0000-0003-3444-1421 1520-6777 PY - 2019 SN - 0733-2467 SP - 353-362 ST - Posttraumatic stress disorder in interstitial cystitis/bladder pain syndrome: Relationship to patient phenotype and clinical practice implications T2 - Neurourology and Urodynamics TI - Posttraumatic stress disorder in interstitial cystitis/bladder pain syndrome: Relationship to patient phenotype and clinical practice implications UR - ://WOS:000454511600041 VL - 38 ID - 1972 ER - TY - JOUR AB - Adolescents, whose parents have cancer, may manifest their distress through changes in school performance, physical complaints of pain and discomfort, as well as changes in social and interpersonal relations. In Asian's tightly-knitted families this matter would be very severe. There has been very little research about the effects of cancer on adolescents in Iran, so the purpose of this study was to explore the Iranian adolescents' experiences about living a parent with cancer. The present study is a quantitative part of a mixed method research with one group, pretest-posttest design. The sample of this study was 30 adolescents. A supportive-educative program was presented to them and one month later the effect of this program was examined by DASS-21 questionnaire. T-test showed that the mean of depression, stress and anxiety had significant statistical differences before and after the program's presentation (p=0.0001). Also, before and after presenting program, there were significant statistical differences in some aspects of quality of life like physical functioning (p=.014), energy/fatigue (p=.000), emotional well-being (p=.0001), social functioning (p=.001), pain (p=.0001), general health (p=.016), subcategory of physical health (p=.0001) and subcategory of psychological health (p=.0001). Our research asserted that, in Iran because of families' structure, the adolescents who live with parents having cancer, have many psychological problems like stress, anxiety, depression and changes in quality of life due to lack of information about cancer and support from others, therefore presenting a supportive-educative program for them could reduce these factors. AN - WOS:000395756400037 AU - Mehrdad, A. AU - Fariba, T. AU - Azadeh, M. AU - Shirin, S. IS - 11 N1 - Mehrdad, Azarbarzin Fariba, Taleghani Azadeh, Malekian Shirin, Saniejlal Azarbarzin, Mehrdad/Q-5887-2017 Azarbarzin, Mehrdad/0000-0002-8824-8515 PY - 2016 SN - 2319-5886 SP - 245-251 ST - When your parents have cancer: adolescents' psychosocial aspects T2 - International Journal of Medical Research & Health Sciences TI - When your parents have cancer: adolescents' psychosocial aspects UR - ://WOS:000395756400037 VL - 5 ID - 2190 ER - TY - JOUR AB - Objective: To evaluate the application of biobehavioral therapies in the management of recurrent headaches of benign nature, in Indian school children. Design: Prospective outpatients. Setting: Child psychiatric clinic at a teaching hospital. Patients: Eighteen children (11 boys and 7 girls) suffering from benign, recurrent headache with duration of more than six months. Main Outcome Measures: All the children were given a treatment package consisting of brief relaxation exercises for children, problem-solving especially related to academic performance, and cognitive restructuring. Parents were counseled for their reactions to the child's problem. Results: Majority of the children had psychosocial stresses, pathological study style, and were over-sensitive. With the current intervention, improvement in all dimensions of headache was observed by both the children and their parents. An increase in the child's coping ability was also felt by the parents. Conclusion: In Indian school children, the application of biobehavioral methods in the treatment of headache was as effective as reported elsewhere. Parents played an important role in the intervention as both co-therapist and motivating agent. AN - WOS:A1992KD68000009 AU - Mehta, M. IS - 4 N1 - Mehta, m PY - 1992 SP - 426-430 ST - BIOBEHAVIORAL INTERVENTION IN RECURRENT HEADACHES IN CHILDREN T2 - Headache Quarterly-Current Treatment and Research TI - BIOBEHAVIORAL INTERVENTION IN RECURRENT HEADACHES IN CHILDREN UR - ://WOS:A1992KD68000009 VL - 3 ID - 2958 ER - TY - JOUR AB - BACKGROUND: Accumulating evidence supports an association between an unhealthy mental state and low back pain (LBP). However, the degree of the association between mental health and chronic low back pain (CLBP) in the general population is poorly understood. The objective of this study was to analyze the incidence of CLBP in Chinese college students and to examine the association between students' unhealthy mental states and the prevalence of CLBP. METHODS: This is a cross-sectional study. A total of 10,000 questionnaires were distributed in the second semester of the 2017-2018 academic year by the School of Medicine, Shanghai JiaoTong University. Eligible participants were students aged ≥ 18 years from randomly selected Chinese colleges. Participants completed a questionnaire survey that included items from the Symptom Checklist-90 (SCL-90) and items on demographic factors, LBP prevalence, quality of life at their university, study-related stress and interpersonal relationships. The evaluation of students' mental states in the survey was divided into two major parts: direct and indirect indicators. A multivariate logistic regression model was mainly used to explore the relationship between CLBP and the students' mental health. RESULTS: There was a high incidence of CLBP in the college students. Multiple logistic regression analysis indicated that the risk of CLBP increased with increasing scores on the SCL-90, and a clinically unhealthy mental state (scores greater than 3) was significantly associated with CLBP (adjusted odds ratios for depression, anxiety, coercion, paranoia, and interpersonal sensitivity were 7.209, 6.593, 3.959, 4.465, and 4.283, respectively; p < 0.001). Participants who had poor living habits or uncomfortable campus lives and those who experienced heavy academic pressure also showed a higher positive association with CLBP compared with the full sample. CONCLUSIONS: Unhealthy psychological conditions, which may be attributed to unsatisfying school lives, excessive learning pressure, and uncomfortable interpersonal relationships, represent a risk factor for CLBP in college students. AD - 1Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080 China. ISNI: 0000 0004 0368 8293. GRID: grid.16821.3c 2Trauma Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 650 Xin Songjiang Road, Shanghai, 201620 People's Republic of China. ISNI: 0000 0004 0368 8293. GRID: grid.16821.3c AN - 31236133 AU - Mei, Q. AU - Li, C. AU - Yin, Y. AU - Wang, Q. AU - Wang, Q. AU - Deng, G. C2 - PMC6580587 DO - 10.1186/s13034-019-0283-2 DP - NLM ET - 2019/06/27 KW - Clbp Chinese college students Scl-90 Unhealthy mental states LA - eng N1 - 1753-2000 Mei, Qixiang Li, Chunlin Yin, Yue Wang, Qi Wang, Qiugen Deng, Guoying Orcid: 0000-0002-1693-8453 Journal Article Child Adolesc Psychiatry Ment Health. 2019 Jun 17;13:24. doi: 10.1186/s13034-019-0283-2. eCollection 2019. PY - 2019 SN - 1753-2000 (Print) 1753-2000 SP - 24 ST - The relationship between the psychological stress of adolescents in school and the prevalence of chronic low back pain: a cross-sectional study in China T2 - Child Adolesc Psychiatry Ment Health TI - The relationship between the psychological stress of adolescents in school and the prevalence of chronic low back pain: a cross-sectional study in China VL - 13 ID - 4161 ER - TY - JOUR AB - OBJECTIVE: To evaluate driving performance, cognition, and balance in patients with chronic nonmalignant pain before and after the addition of transdermal fentanyl to their treatments. DESIGN: Prospective, one-group pretest-posttest design. SETTING: Outpatient pain center associated with a large, urban medical school. INTERVENTIONS: Patients taking less than a 15-mg equivalent of oxycodone per day took baseline driving performance, cognitive, and balance tests. Transdermal fentanyl was initiated and titrated in 25-microg/hour increments, weighing benefits and side effects. At the end of a 1-month period, the achieved dose was maintained for another month. After they were stabilized for 1 month, patients repeated driving, cognitive, and balance tests. RESULTS: Twenty three patients completed the study; three discontinued secondary to side effects. The median dose at the end of the titration period was 50 microg/hour (48%). No differences were found in driving simulation measures between the pretreatment and posttreatment periods. No decrements in cognitive performance were found. Improvements in visual motor tracking, visual memory, and attention were found during treatment with transdermal fentanyl. No differences in balance or body sway were found. Pain decreased over the course of treatment. CONCLUSIONS: The addition of transdermal fentanyl to a treatment regimen containing no opiates or small amounts of opiates for patients with chronic nonmalignant pain did not negatively affect their driving performances, reaction times, cognition, or balance. Future studies in this area are needed to guide treatment decisions. AD - Jefferson Medical College, Department of Anesthesiology, Philadelphia, Pennsylvania 19107, USA. Lynette.Menefee@jefferson.edu AN - 14996236 AU - Menefee, L. A. AU - Frank, E. D. AU - Crerand, C. AU - Jalali, S. AU - Park, J. AU - Sanschagrin, K. AU - Besser, M. DA - Mar DO - 10.1111/j.1526-4637.2004.04005.x DP - NLM ET - 2004/03/05 IS - 1 KW - Administration, Cutaneous Adolescent Adult Aged *Automobile Driving/psychology Chronic Disease Cognition/*drug effects/physiology Female Fentanyl/*administration & dosage Humans Male Middle Aged Pain/*drug therapy/psychology Postural Balance/*drug effects/physiology Prospective Studies Psychomotor Performance/*drug effects/physiology Statistics, Nonparametric LA - eng N1 - Menefee, Lynette A Frank, Evan D Crerand, Canice Jalali, Shailen Park, John Sanschagrin, Kim Besser, Marcus Comparative Study Journal Article Research Support, Non-U.S. Gov't England Pain Med. 2004 Mar;5(1):42-9. doi: 10.1111/j.1526-4637.2004.04005.x. PY - 2004 SN - 1526-2375 (Print) 1526-2375 SP - 42-9 ST - The effects of transdermal fentanyl on driving, cognitive performance, and balance in patients with chronic nonmalignant pain conditions T2 - Pain Med TI - The effects of transdermal fentanyl on driving, cognitive performance, and balance in patients with chronic nonmalignant pain conditions VL - 5 ID - 3675 ER - TY - JOUR AB - BACKGROUND: There is scant literature evaluating the indications, techniques, and outcomes of minimally invasive spine (MIS) surgery undertaken for pediatric and adolescent spine pathology. Our study attempts to evaluate the safe and effective use of MIS techniques in pediatric and adolescent patients and to appreciate the technical nuances of MIS surgery for this age group. METHODS: Consecutive pediatric and adolescent patients undergoing elective MIS lumbar procedures, from 2008 to 2016, were retrospectively analyzed from the practice of a single fellowship-trained academic spinal neurosurgeon. Information was retrieved regarding procedure and disease pathology. Descriptive data was obtained including age, sex, body mass index (BMI), insurance coverage, smoking status, and co-morbidities. Outcome measures were recorded including intraoperative complications, revision surgery, and return-to-function. RESULTS: Sixteen patients underwent 17 surgeries. The median BMI was 29.2 (range, 20.8-41.5). Age ranged from 12 to 19 years. Nearly 20% of the patients in our series were smokers. Most patients underwent discectomy, with L5-S1 being the most common level. One patient underwent direct pars defect repair and another underwent recurrent discectomy. More than 90% of the patients were complication-free at follow-up period of 6 months. One patient had a recurrent disc herniation and another had a superficial wound infection. Overall, 82.4% patients enjoyed full return to sports such as weight lifting, gymnastics, and contact sports. One patient required pain management to help alleviate ongoing pain. Another patient required a course of outpatient rehabilitation to help with a "foot drop." CONCLUSION: Our series illustrates the effective application of MIS techniques among carefully selected pediatric patients. Emphasis is on using a smaller (16 mm) tubular retractor and causing minimal disruption of paraspinal osseo-tendinous structures. MIS techniques can be successfully applied to the pediatric and adolescent age group. AD - Department of Neurosurgery, LSUHSC, Shreveport, Louisiana, USA. AN - 29963325 AU - Menger, R. AU - Hefner, M. I. AU - Savardekar, A. R. AU - Nanda, A. AU - Sin, A. C2 - PMC6000717 DO - 10.4103/sni.sni_417_17 DP - NLM ET - 2018/07/03 KW - Adolescent spine surgery direct pars repair minimally invasive spine surgery pediatric discectomy pediatric laminectomy pediatric spine surgery LA - eng N1 - 2152-7806 Menger, Richard Hefner, Matthew I Savardekar, Amey R Nanda, Anil Sin, Anthony Journal Article Surg Neurol Int. 2018 Jun 7;9:116. doi: 10.4103/sni.sni_417_17. eCollection 2018. PY - 2018 SN - 2229-5097 (Print) 2152-7806 SP - 116 ST - Minimally invasive spine surgery in the pediatric and adolescent population: A case series T2 - Surg Neurol Int TI - Minimally invasive spine surgery in the pediatric and adolescent population: A case series VL - 9 ID - 4142 ER - TY - JOUR AB - BACKGROUND: Headache disorders are the most common complaints worldwide. Migraine, tension type and cluster headaches account for majority of primary headaches and improvise a substantial burden on the individual, family or society at large. There is a scanty data on the prevalence of primary headaches in sub-Saharan Africa in general and Ethiopia in particular. Moreover there is no population based urban study in Ethiopia. The purpose of this study is to determine the prevalence and burden of primary headaches in local community in Addis Ababa, Ethiopia. METHODS: Cross-sectional sample survey was carried out in Addis Ketema sub city, Kebele 16/17/18 (local smallest administrative unit). Using systematic random sampling, data were collected by previously used headache questionnaire, over a period of 20 days. RESULTS: The study subjects were 231 of which 51.5% were males and 48.5% were females. The overall one year prevalence of primary headache disorders was 21.6% and that for migraine was 10%, migraine without aura 6.5% migraine with aura was 2.6% and probable migraine was 0.9%. The prevalence of tension type of headache was found to be 10.4%, frequent episodic tension type headache was 8.2% followed by infrequent tension type headache of 2.2%. The prevalence of cluster headache was 1.3%. The burden of primary headache disorders in terms of missing working, school or social activities was 68.0%. This was 78.3% for migraineurs and 66.7% for tension type headache. Majority 92.0% of primary headache cases were not using health services and 66.0% did not use any drug or medications during the acute attacks and none were using preventive therapy. CONCLUSION: Prevalence and burden of primary headache disorders was substantial in this community. Health service utilization of the community for headache treatment was poor. AD - Department of Neurology, School of Medicine, Addis Ababa University, P,O, Box: 2380, Addis Ababa, Ethiopia. getahaau@yahoo.com AN - 23574933 AU - Mengistu, G. AU - Alemayehu, S. C2 - PMC3620379 DA - Mar 28 DO - 10.1186/1129-2377-14-30 DP - NLM ET - 2013/04/12 IS - 1 KW - Adolescent Adult Age Distribution Aged Aged, 80 and over Cross-Sectional Studies Ethiopia/epidemiology Female Headache Disorders, Primary/*epidemiology Humans Male Middle Aged Prevalence Sex Distribution Surveys and Questionnaires Young Adult LA - eng N1 - 1129-2377 Mengistu, Getahun Alemayehu, Samson Journal Article J Headache Pain. 2013 Mar 28;14(1):30. doi: 10.1186/1129-2377-14-30. PY - 2013 SN - 1129-2369 (Print) 1129-2369 SP - 30 ST - Prevalence and burden of primary headache disorders among a local community in Addis Ababa, Ethiopia T2 - J Headache Pain TI - Prevalence and burden of primary headache disorders among a local community in Addis Ababa, Ethiopia VL - 14 ID - 3806 ER - TY - JOUR AB - A number of psychosocial factors have been associated with the onset, exacerbation and/or maintenance of chronic pain in adolescents. The present study was conducted to evaluate the relative importance of vulnerability, reinforcement, and modeling. We compared 222 adolescents with chronic pain and no documented physiological etiology (headache, back, limb and abdominal pain) with 148 controls and their (respectively 183 vs. 127) parents. Analyses showed that adolescents with chronic pain are more vulnerable in terms of neuroticism, negative fear of failure, and (less) experienced social acceptance. Contrary to our expectations, the chronic pain group experienced less reinforcement for their pain behavior by both parents and peers than the control group. While the number of pain models was higher in the chronic pain group, no differences were found between their parents and those of the adolescents without chronic pain in pain experience, pain parameters, and pain coping. Regression analyses on the contribution of psychosocial factors to chronic pain and its parameters sustained the positive relation between vulnerability, (less) pain reinforcement, pain models and coping with pain. Furthermore, we also found evidence that gender differences have to be taken into account. (C) 2002 Published by Elsevier Science B.V. on behalf of International Association for the Study of Pain. AN - WOS:000180588200004 AU - Merlijn, Vpbm AU - Hunfeld, J. A. M. AU - van der Wouden, J. C. AU - Hazebroek-Kampschreur, Aajm AU - Koes, B. W. AU - Passchier, J. DA - Jan DO - 10.1016/s0304-3959(02)00289-0 IS - 1-2 N1 - Merlijn, VPBM Hunfeld, JAM van der Wouden, JC Hazebroek-Kampschreur, AAJM Koes, BW Passchier, J van der Wouden, Johannes C/O-5109-2019; Koes, Bart w/K-4614-2016; van der Wouden, Johannes C/C-2597-2009 van der Wouden, Johannes C/0000-0001-6639-6050; Koes, Bart w/0000-0002-0450-9969; PY - 2003 SN - 0304-3959 SP - 33-43 ST - Psychosocial factors associated with chronic pain in adolescents T2 - Pain TI - Psychosocial factors associated with chronic pain in adolescents UR - ://WOS:000180588200004 VL - 101 ID - 2816 ER - TY - JOUR AB - Postoperative pain management is still in need of vast improvement, especially for children. The aim of this article is to demonstrate which structures and processes must be optimized to ultimately improve patient satisfaction and safety. Basic prerequisites are among others personnel continuity and good cooperation in a multiprofessional team. A clear assignment of responsibilities is also of essential importance. On admission every patient should be questioned on the currently existing pain. Patients or the parents must be informed about the pain therapy in a comprehensible manner. Possible complications, chances of success, advantages and disadvantages of the planned procedure and alternative forms of treatment must be discussed. The implementation needs a great deal of consideration. The introduction of clearly defined pathways and thorough schooling contribute more to successful pain management than the establishment of pain measurement or the use of special techniques alone. Because pain intensity can only be described indirectly it is difficult to assess in children. Assessment is made by another person until children are 5 years old. The gold standard in pain measurement is, however, self-estimation using appropriate scales which is possible for older children. The routinely carried out representation of pain values and prompt documentation of all pain therapeutic measures are indispensible for the control and optimization of pain therapy. Whether improvements in acute pediatric pain therapy will actually be achieved can only be realized by standardized compilation and analysis of the quality of therapy. For this purpose QUIPSInfant was developed. AN - WOS:000331647400003 AU - Messerer, B. AU - Sandner-Kiesling, A. DA - Feb DO - 10.1007/s00482-013-1383-1 IS - 1 N1 - Messerer, B. Sandner-Kiesling, A. 1432-2129 PY - 2014 SN - 0932-433X SP - 14-24 ST - Organization of pediatric pain management. Austrian interdisciplinary recommendations for pediatric perioperative pain management T2 - Schmerz TI - Organization of pediatric pain management. Austrian interdisciplinary recommendations for pediatric perioperative pain management UR - ://WOS:000331647400003 VL - 28 ID - 2323 ER - TY - JOUR AB - PURPOSE: To investigate the prevalence of low back pain (LBP) and the association with home posture habits while watching TV and using the computer in adolescents. METHODS: This is a cross-sectional study with high school adolescents in Rio de Janeiro, Brazil. Students answered questions regarding sociodemographic variables, lifestyle, posture (illustration), time watching TV, time using computer, time playing video game and the presence and impact of LBP. Multivariate logistic regression was used to investigate the association between home posture habits and LBP. RESULTS: The prevalence of LBP was 46.8 % (18.2 % chronic low back pain [CLBP] and 28.6 % acute low back pain [ALBP]). As LBP consequence, 23 % (n = 253) of the students took medication, 9.1 % (n = 100) missed classes and 8.2 % (n = 90) sought a physician. Slump postures while watching TV and using the desktop computer were associated with CLBP (OR 3.22, 95 % CI 1.38-7.5 and OR 1.7, 95 % CI 1.06-2.73, respectively). Participants who watched TV seated in bed yielded an OR of 2.14 (95 % CI 1.06-4.32) for ALBP and who used the notebook lying belly down in bed yielded an odds ratio (OR) of 2.26 (95 % CI 1.02-5.01) for ALBP. Among confounding factors, female sex was associated with CLBP and ALBP, work (no) was a protective factor associated with ALBP. CONCLUSION: Our findings support the high prevalence and the substantial impact of LBP in late adolescence and add the association with inappropriate home postural habits. AU - Meziat Filho, Ney AU - Coutinho, Evandro Silva AU - Azevedo e Silva, Gulnar DA - 2015/03// DO - 10.1007/s00586-014-3571-9 DP - PubMed IS - 3 J2 - Eur Spine J KW - Acute Disease Adolescent Brazil Chronic Pain Cross-Sectional Studies Female Habits Humans Life Style Logistic Models Low Back Pain Male Odds Ratio Posture Prevalence Risk Factors Surveys and Questionnaires Young Adult LA - eng PY - 2015 SN - 1432-0932 SP - 425-433 ST - Association between home posture habits and low back pain in high school adolescents T2 - European Spine Journal: Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society TI - Association between home posture habits and low back pain in high school adolescents UR - http://www.ncbi.nlm.nih.gov/pubmed/25212451 VL - 24 ID - 88 ER - TY - JOUR AB - OBJECTIVE: To assess the costs of headache-related absenteeism of community-dwelling migraineurs, and to compare the amount of absenteeism between migraineurs aged 18 and older and age, sex, and occupation-matched nonheadache-prone subjects. DESIGN: Follow-up over a 3-month period. SAMPLES: 385 migraineurs and 313 nonheadache subjects representative of the setting. METHODS: Every day, the participants recorded the presence of headache, if any, and the work situation (unemployment, holiday, weekend, medical reason, nonmedical reason). Sickness-related absenteeism was the number of workdays missed or interrupted for medical reasons. Headache-related absenteeism was the sickness-related absenteeism during workdays with headaches. The annual headache-related absenteeism costs in France were extrapolated from these data in accordance with the mean income per occupational category. The incremental absenteeism and related costs were the difference between the two samples. RESULTS: Of working migraineurs, 20% had at least one period of absenteeism. During the 3 months, they missed or interrupted on average 1.4 days for medical reasons, 0.25 of which for headaches. Sickness-related absenteeism was statistically higher in migraineurs than in nonheadache-prone subjects. This difference was due to a higher absenteeism for comorbidity reasons, not for headache reasons, representing 20% of all sickness-related absenteeism. Migraineurs avoided sick leave for headache reasons. As an incremental total, 1.68 days or approximately 0.7% of the annual number of working days are lost on average per individual with migraine. The annual incremental headache-related absenteeism cost was 5.22 billions, i.e. 1,551 FF (US$240) per migraineur. AD - CCECQA, CHU Bordeaux, France. philippe.michel@ph.u-bordeaux2.fr AN - 10403066 AU - Michel, P. AU - Dartigues, J. F. AU - Duru, G. AU - Moreau, J. AU - Salamon, R. AU - Henry, P. DA - Jun DO - 10.1046/j.1468-2982.1999.019005503.x DP - NLM ET - 1999/07/14 IS - 5 KW - *Absenteeism Adolescent Adult Aged Cohort Studies Costs and Cost Analysis Cross-Sectional Studies Female France/epidemiology Health Surveys Humans Incidence Male Medical Records Middle Aged Migraine Disorders/diagnosis/economics/*epidemiology Prospective Studies Sick Leave/economics/statistics & numerical data LA - eng N1 - Michel, P Dartigues, J F Duru, G Moreau, J Salamon, R Henry, P Journal Article Research Support, Non-U.S. Gov't England Cephalalgia. 1999 Jun;19(5):503-10. doi: 10.1046/j.1468-2982.1999.019005503.x. PY - 1999 SN - 0333-1024 (Print) 0333-1024 SP - 503-10 ST - Incremental absenteeism due to headaches in migraine: results from the Mig-Access French national cohort T2 - Cephalalgia TI - Incremental absenteeism due to headaches in migraine: results from the Mig-Access French national cohort VL - 19 ID - 3387 ER - TY - JOUR AB - Rheumatic diseases in childhood and adolescence differ from those of adulthood according to type, manifestation, treatment and course. A specialized therapy, starting as early as possible, improves the prognosis, can prevent long-term damage and saves the costs of long-term care. Only a specialized pediatric care system can guarantee optimum quality of the processes involved and the results for rheumatology in childhood and adolescence within a global financial system. This requires adequate structural quality of the specialized clinics and departments for pediatric rheumatology. The management of rheumatic diseases in childhood and adolescence is comprehensive and requires a multidisciplinary, specialized and engaged team which can cover the whole spectrum of rheumatic diseases with their various age-dependent aspects. In order to guarantee an adequate, cost-efficient routine, a specialized center which concentrates on inpatient care should treat at least 300 patients with pediatric rheumatic diseases per year. The diagnoses should be divided among the various disease categories with at least 70% of them involving inflammatory rheumatic diseases. For the inpatient care of small children, an accompanying person (parent) is necessary, requiring adequate structures and services. Patient rooms as well as diagnostic (radiography, sonography, etc.) and therapeutic services (physiotherapy, occupational therapy, pool, etc.) must be adequate for small children and school children as well as adolescents. Suitable mother-child units must also be provided and a school for patients is required within the clinic. A pediatric rheumatologist must be available 24 h a day, and it must be possible to reach other specialists within a short time. For painful therapeutic procedures, age-appropriate pain management is obligatory. A continuous adjustment of these recommendations to changing conditions in health politics is intended. AD - Deutsches Zentrum für Kinder- und Jugendrheumatologie, Gehfeldstrasse 24, 82467, Garmisch-Partenkirchen. michels.hartmut@rummelsberger.net AN - 16710651 AU - Michels, H. AU - Ganser, G. AU - Dannecker, G. AU - Forster, J. AU - Häfner, R. AU - Horneff, G. AU - Küster, R. M. AU - Lakomek, H. J. AU - Lehmann, H. AU - Minden, K. AU - Rogalski, B. AU - Schöntube, M. DA - Jul DO - 10.1007/s00393-006-0056-1 DP - NLM ET - 2006/05/20 IS - 4 KW - Adolescent Child Cost-Benefit Analysis/standards Early Diagnosis Germany Health Services Needs and Demand/standards Hospital Departments/*standards Hospital Design and Construction/*statistics & numerical data Hospitals, Pediatric/*standards Hospitals, Special/*standards Humans Outcome Assessment, Health Care/standards Patient Care Team/*standards Quality Assurance, Health Care/*standards Rheumatic Diseases/diagnosis/*therapy Specialization/standards LA - ger N1 - Michels, H Ganser, G Dannecker, G Forster, J Häfner, R Horneff, G Küster, R M Lakomek, H-J Lehmann, H Minden, K Rogalski, B Schöntube, M Gesellschaft für Kinder - und Jugendrheumatologie (GKJR) Verbandes Rheumatologischer Akutkliniken (VRA) Journal Article Germany Z Rheumatol. 2006 Jul;65(4):315-22, 324-6. doi: 10.1007/s00393-006-0056-1. OP - Strukturqualität von kinder- und jugendrheumatologischen Akutkliniken und -abteilungen. Projektgruppenarbeit der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR) und des Verbandes Rheumatologischer Akutkliniken (VRA). PY - 2006 SN - 0340-1855 (Print) 0340-1855 SP - 315-22, 324-6 ST - [Structural quality of rheumatology clinics for children and adolescents. Paper by a task force of the "Society of Pediatric and Adolescent Rheumatology" and of the "Association of Rheumatology Clinics in Germany"] T2 - Z Rheumatol TI - [Structural quality of rheumatology clinics for children and adolescents. Paper by a task force of the "Society of Pediatric and Adolescent Rheumatology" and of the "Association of Rheumatology Clinics in Germany"] VL - 65 ID - 3921 ER - TY - JOUR AB - The quantification of the social and economic handicaps caused by headache is a complex problem, especially given the great variability of headache patients' clinical pictures. In the present study, 400 patients, consecutively admitted to Headache Centers in Pavia and Milan, were interviewed on the relationship between headache and their work and social activities, in order to evaluate their socioeconomic handicap due to headache. The analysis of the data primarily focused on attack-type headaches (migraine, cluster headache, and episodic tension-type headache) and chronic or daily headaches (chronic tension-type headache and migraine combined with tension-type headache). These latter types were often characterized by the daily use or abuse of analgesics. The overall profile which emerged from the study reveals relatively low levels of handicap or disability in work and social activities. These low levels can be mainly attributed to timely, and at times excessive, use of analgesics. AD - Headache Center, Neurological Institute C. Mondino, University of Pavia, Italy. AN - 7721572 AU - Micieli, G. AU - Frediani, F. AU - Cavallini, A. AU - Rossi, F. AU - Bussone, G. AU - Merli, S. AU - Nappi, G. DA - Mar DO - 10.1111/j.1526-4610.1995.hed3503131.x DP - NLM ET - 1995/03/01 IS - 3 KW - Absenteeism Adolescent Adult Aged Child *Disability Evaluation Employment Female Headache/*diagnosis/drug therapy Humans Leisure Activities Male Middle Aged Retrospective Studies LA - eng N1 - Micieli, G Frediani, F Cavallini, A Rossi, F Bussone, G Merli, S Nappi, G Journal Article United States Headache. 1995 Mar;35(3):131-7. doi: 10.1111/j.1526-4610.1995.hed3503131.x. PY - 1995 SN - 0017-8748 (Print) 0017-8748 SP - 131-7 ST - Quantification of headache disability: a diagnostic-based approach T2 - Headache TI - Quantification of headache disability: a diagnostic-based approach VL - 35 ID - 3522 ER - TY - JOUR AB - OBJECT: The object of this study was to compare symptom status and neurocognitive functioning in athletes with no headache (non-HA group), athletes complaining of headache (HA group), and athletes with characteristics of posttraumatic migraine (PTM group). METHODS: Neurocognitive tests were undertaken by 261 high-school and collegiate athletes with a mean age of 16.36 +/- 2.6 years. Athletes were separated into three groups: the PTM group (74 athletes with a mean age of 16.39 +/- 3.06 years), the HA group (124 athletes with a mean age of 16.44 +/- 2.51 years), and the non-HA group (63 patients with a mean age of 16.14 +/- 2.18 years). Neurocognitive summary scores (outcome measures) for verbal and visual memory, visual motor speed, reaction time, and total symptom scores were collected using ImPACT, a computer software program designed to assess sports-related concussion. Significant differences existed among the three groups for all outcome measures. The PTM group demonstrated significantly greater neurocognitive deficits when compared with the HA and non-HA groups. The PTM group also exhibited the greatest amount of departure from baseline scores. CONCLUSIONS: The differences among these groups can be used as a basis to argue that PTM characteristics triggered by sports-related concussion are related to increased neurocognitive dysfunction following mild traumatic brain injury. Thus, athletes suffering a concussion accompanied by PTM should be examined in a setting that includes symptom status and neurocognitive testing to address their recovery more fully. Given the increased impairments observed in the PTM group, in this population clinicians should exercise increased caution in decisions about treatment and when the athlete should be allowed to return to play. AD - Department of Sports Medicine and Nutrition, School of Health and Rehabilitation Sciences, University of Pittsburgh Medical Center, Pennsylvania 15203, USA. AN - 15926709 AU - Mihalik, J. P. AU - Stump, J. E. AU - Collins, M. W. AU - Lovell, M. R. AU - Field, M. AU - Maroon, J. C. DA - May DO - 10.3171/jns.2005.102.5.0850 DP - NLM ET - 2005/06/02 IS - 5 KW - Adolescent Athletic Injuries/*complications/rehabilitation Brain Concussion/*complications Cognition Disorders/diagnosis/etiology Female Humans Male Migraine Disorders/*etiology/*physiopathology/rehabilitation Neurologic Examination LA - eng N1 - Mihalik, Jason P Stump, Jamie E Collins, Michael W Lovell, Mark R Field, Melvin Maroon, Joseph C Comparative Study Journal Article United States J Neurosurg. 2005 May;102(5):850-5. doi: 10.3171/jns.2005.102.5.0850. PY - 2005 SN - 0022-3085 (Print) 0022-3085 SP - 850-5 ST - Posttraumatic migraine characteristics in athletes following sports-related concussion T2 - J Neurosurg TI - Posttraumatic migraine characteristics in athletes following sports-related concussion VL - 102 ID - 3604 ER - TY - JOUR AB - Objective, To study the prevalence of joint hypermobility and the association of hypermobility with musculoskeletal pain in pre-adolescents. Methods. Finnish school children in the 3rd and 5th grade, n = 1637, mean ages 9.8 and 11.8 years, were studied by Beighton criteria for joint hypermobility, with total score greater than or equal to 6 as a cutoff point for hypermobility, pretested questionnaire for musculoskeletal pain, and classification to different pain groups on the basis of painful body area and frequency of pain. Results, The mean Beighton scores were 2.7 and 2.4 for the 3rd and 5th grade children, respectively. Total score was greater than or equal to 6 in 7.8% of the children. No association of hypermobility with musculoskeletal pain was found. Of the hypermobile children, 29.9% (95% CI 22.3 to 38.8), and of the nonhypermobile children, 32.3% (95% CI 29.9 to 34.7) had musculoskeletal pain at least once a week. Children with hypermobility did not have more pain due to injuries. Disability caused by musculoskeletal pain did not correlate with Beighton total score. Conclusion, Both joint hypermobility and musculoskeletal pain are common in pre-adolescents. Hypermobility appears not to be a contributing factor to musculoskeletal pain in pre-adolescents. AN - WOS:A1996VR07500027 AU - Mikkelsson, M. AU - Salminen, J. J. AU - Kautiainen, K. DA - Nov IS - 11 N1 - Mikkelsson, M Salminen, JJ Kautiainen, K PY - 1996 SN - 0315-162X SP - 1963-1967 ST - Joint hypermobility is not a contributing factor to musculoskeletal pain in pre-adolescents T2 - Journal of Rheumatology TI - Joint hypermobility is not a contributing factor to musculoskeletal pain in pre-adolescents UR - ://WOS:A1996VR07500027 VL - 23 ID - 2919 ER - TY - JOUR AB - Objectives. To study the association of musculoskeletal pain with emotional and behavioral problems, especially depressive symptoms in Finnish preadolescents. Study Design. A structured pain questionnaire was completed by 1756 third- and fifth-grade schoolchildren for identifying children with widespread pain (WSP), children with neck pain (NP), and pain-free controls for the comparative study. There were 124 children with WSP (mean age, 10.7 years), 108 children with NP (mean age, 11.1 years), and 131 controls (mean age, 10.7 years) who completed the Children's Depression Inventory (CDI) and a sleep questionnaire. A blinded clinical examination was done to detect fibromyalgia. For parental evaluation, the Child Behavior Checklist and a sociodemographic questionnaire were used. For teacher evaluation the Teacher Report Form was used. Results. Children with WSP had significantly higher total emotional and behavioral scores than controls, according to child and parent evaluation. A significant difference in the mean total CDI scores was also found between the WSP and NP groups. Children with fibromyalgia had significantly higher CDI scores than the other children with WSP. Conclusions. Musculoskeletal pain, especially fibromyalgia, and depressive symptoms had high comorbidity. Pain and depressive symptoms should be recognized to prevent a chronic pain problem. AN - WOS:A1997XP05000010 AU - Mikkelsson, M. AU - Sourander, A. AU - Piha, J. AU - Salminen, J. J. DA - Aug DO - 10.1542/peds.100.2.220 IS - 2 N1 - Mikkelsson, M Sourander, A Piha, J Salminen, JJ Sourander, Andre/0000-0003-0361-7244 PY - 1997 SN - 0031-4005 SP - 220-227 ST - Psychiatric symptoms in preadolescents with musculoskeletal pain and fibromyalgia T2 - Pediatrics TI - Psychiatric symptoms in preadolescents with musculoskeletal pain and fibromyalgia UR - ://WOS:A1997XP05000010 VL - 100 ID - 2907 ER - TY - JOUR AB - The aims of this study were to prospectively follow up population-based cohorts of children with widespread pain, children with neck pain and pain-free children, in order to evaluate 1-y changes in pain symptoms and to evaluate predictors for persistent widespread pain and for the change of neck pain to widespread pain. A structured pain questionnaire, the Children's Depression Inventory, and a sleep questionnaire were completed by the pre-adolescent cohorts, and clinical evaluation with tender point palpation and pain threshold measurements was carried out in both years. The Child Behavior Checklist, the Teacher's Report Form and a sociodemographic questionnaire were completed at baseline. More children in the 2 pain cohorts reported pain at follow-up than did controls (p < 0.0001). Children with persistent widespread pain had lower pain thresholds compared with those whose pain classification changed. In the neck pain group, 19 (20.4%) reported widespread pain at follow-up. Although depressive symptoms and sleep problems were associated with the change of neck pain to widespread pain, neither they nor other measured factors showed independent explanatory power in multiple logistic regression analysis. In conclusion, fluctuation of pain symptoms occurred mainly among pain cohorts. Depressive and sleep problems may have an effect on the spreading of regional neck pain to widespread pain. Pain threshold measurement and evaluation of depressive and sleep problems may be useful tools for secondary prevention of musculoskeletal pain in pre-adolescents. AD - Rehabilitation Center, Rheumatism Foundation Hospital, Heinola, Finland. kesto@sci.fi AN - 10565460 AU - Mikkelsson, M. AU - Sourander, A. AU - Salminen, J. J. AU - Kautiainen, H. AU - Piha, J. DA - Oct DO - 10.1080/08035259950168199 DP - NLM ET - 1999/11/24 IS - 10 KW - Adolescent Age Distribution Child Comorbidity Confidence Intervals Cross-Sectional Studies Depressive Disorder/diagnosis/*epidemiology Female Finland/epidemiology Follow-Up Studies Humans Incidence Logistic Models Longitudinal Studies Male Multivariate Analysis Musculoskeletal Diseases/*epidemiology Neck Pain/diagnosis/*epidemiology Pain Measurement Pain, Intractable/diagnosis/epidemiology Prospective Studies Risk Factors Sex Distribution Surveys and Questionnaires LA - eng N1 - Mikkelsson, M Sourander, A Salminen, J J Kautiainen, H Piha, J Journal Article Research Support, Non-U.S. Gov't Norway Acta Paediatr. 1999 Oct;88(10):1119-24. doi: 10.1080/08035259950168199. PY - 1999 SN - 0803-5253 (Print) 0803-5253 SP - 1119-24 ST - Widespread pain and neck pain in schoolchildren. A prospective one-year follow-up study T2 - Acta Paediatr TI - Widespread pain and neck pain in schoolchildren. A prospective one-year follow-up study VL - 88 ID - 3318 ER - TY - JOUR AB - BackgroundRegular school sports can help adolescents achieve the recommended amount of daily physical activity and provide knowledge, attitudes and behavioral skills that are needed in order to adopt and maintain a physically active lifestyle. Furthermore, it reaches all children including those that are at risk for engaging in more sedentary types of behavior. Since adolescents with juvenile idiopathic arthritis (JIA) are less involved in physical and social activities than their healthy peers, the objectives were to (1) estimate the prevalence of participation in school sports among patients with JIA; (2) determine the correlates associated with school sports absenteeism; and (3) investigate whether attendance in school sports has changed in the era of biologics.MethodsData from schoolchildren with JIA recorded in the German National Paediatric Rheumatologic Database (NPRD) in the years 2000 to 2015 were considered for the analyses. Data from the year 2015 were inspected to analyze correlates of school sports absenteeism. Whether school sports participation had changed between 2000 and 2015 was determined using linear mixed models.ResultsDuring the 15-year period, the participation rates in school sports were determined in 23,016 patients. The proportion of patients who participated in school sports almost always steadily increased from 31% in 2000 to 64% in 2015 (=0.017, 95% confidence interval (CI) 0.015, 0.020), whereas the exemption rate simultaneously decreased from 44% in 2000 to 16% in 2015 [=-0.009, 95% CI -0.011, -0.007]. In 2015, the data from 5879 patients (mean age 13.13.3years, female 65%, disease duration 5.9 +/- 4.0years, persistent oligoarthritis 37%) were available for evaluation. Full exemption from school sports (in 16.1% of cases) was associated with functional limitations, disease activity and any use of DMARDs, intra-articular glucocorticoid injections or physiotherapy.Conclusions School sports attendance among children and adolescents with JIA has increased significantly over the past 15years. Possible explanations include improved functional ability probably due to better treatment options. The integration of patients with child acceptable symptom states who have previously been fully exempted from school sports needs to be addressed in the future. AN - WOS:000458463800001 AU - Milatz, F. AU - Klotsche, J. AU - Niewerth, M. AU - Geisemeyer, N. AU - Trauzeddel, R. AU - Weissbarth-Riedel, E. AU - Kallinich, T. AU - Peitz, J. AU - Hartmann, M. AU - Minden, K. C7 - 6 DA - Feb DO - 10.1186/s12969-019-0306-9 N1 - Milatz, Florian Klotsche, Jens Niewerth, Martina Geisemeyer, Nils Trauzeddel, Ralf Weissbarth-Riedel, Elisabeth Kallinich, Tilmann Peitz, Joachim Hartmann, Matthias Minden, Kirsten PY - 2019 SN - 1546-0096 ST - Participation in school sports among children and adolescents with juvenile idiopathic arthritis in the German National Paediatric Rheumatologic Database, 2000-2015: results from a prospective observational cohort study T2 - Pediatric Rheumatology TI - Participation in school sports among children and adolescents with juvenile idiopathic arthritis in the German National Paediatric Rheumatologic Database, 2000-2015: results from a prospective observational cohort study UR - ://WOS:000458463800001 VL - 17 ID - 1945 ER - TY - JOUR AB - Background: The reduction of school years in grammar schools from 9 to 8 years (G9 vs. G8) is supposed to exhibit increased impairments of health of the latter group of students. Aim of the present study was to investigate whether G8-students are exposed to more stress and report more headaches and other health complaints than G9-students. Participants: 1 260 formers of grammar schools in Munich (10(th) vs. 11(th) form). Methods: In a survey, the frequency of headache and other health complaints, experience of chronic stress and health-related quality of life were assesssed with a questionnaire and compared between the two groups of different grammar-school durations (G8 vs. G9). Results: 83.1 % of all formers reported to suffer from headache at least once per month. Further frequently reported health complaints were back pain (47.7 %), excessive need for sleep (45.6 %) and pain in neck or shoulder (45.0 %). 20.4 % of the formers reported high exposure to stress. The greatest reductions in quality of life were found with respect to school-related and physical wellbeing. As the only significant differences, formers of G8 reported fewer daily leisure time and that available leisure time was not sufficient for recreation. Conclusions: The high prevalence of pain, health complaints and stress indicates high demands to all grammar scholars. High demands due to the reduction of school years in grammar school, however, are not reflected in increased health impairments in these formers, but rather in limited leisure time activities. AN - WOS:000280747600007 AU - Milde-Busch, A. AU - Blaschek, A. AU - Borggrafe, I. AU - von Kries, R. AU - Straube, A. AU - Heinen, F. DA - Jul-Aug DO - 10.1055/s-0030-1252012 IS - 4 N1 - Milde-Busch, A. Blaschek, A. Borggraefe, I. von Kries, R. Straube, A. Heinen, F. Heinen, Florian/B-6594-2015; Borggraefe, Ingo/AAC-4966-2020 Heinen, Florian/0000-0002-3872-6136; 1439-3824 PY - 2010 SN - 0300-8630 SP - 255-260 ST - Is There an Association between the Reduced School Years in Grammar Schools and Headache and Other Health Complaints in Adolescent Students? T2 - Klinische Padiatrie TI - Is There an Association between the Reduced School Years in Grammar Schools and Headache and Other Health Complaints in Adolescent Students? UR - ://WOS:000280747600007 VL - 222 ID - 2547 ER - TY - JOUR AB - Chronic abdominal pain is a common feature of most functional gastrointestinal disorders in children, including functional abdominal pain (FAP) and irritable bowel syndrome (IBS). FAP can impair a child's life and often leads to significant school absences. Although the underlying mechanism is likely multifactorial, early pain experiences during a vulnerable period in the developing nervous system can cause long-term changes in the brain-gut axis and ultimately may result in altered pain pathways and visceral hyperalgesia. Care providers often feel uncomfortable managing patients with chronic abdominal pain, as the pathophysiology is poorly understood, and limited data exist regarding safety and efficacy of therapeutic options in children. The primary goal of therapy in FAP is to alleviate pain symptoms and to help the child return to normal daily activities. Treatment should be individualized and chosen based on the severity of symptoms, the existence of comorbid psychological disorders, and the impact the disorder has on the child's school attendance and normal functioning. Various psychological interventions, such as cognitive-behavioral therapy, hypnosis, and guided imagery, have been successfully used in children with chronic abdominal pain. Pharmacologic therapies such as H(2) blockers, proton-pump inhibitors, tricyclic antidepressants, and various serotonergic drugs have been used, but good controlled trials are lacking. More studies are clearly needed to investigate the benefits and safety of pharmacologic therapy in children. Newer pharmacologic agents that target specific receptors involved in nociception, stress, and neurogenic inflammation currently are being developed. Future targets for visceral hyperalgesia should not only be aimed at alleviating symptoms but also should include prevention, particularly in cases with a suspected sensitizing event such as neonatal pain and postinfectious IBS. AD - Division of Pediatric Gastroenterology, Hepatology and Nutrition, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA. amiranda@mail.mcw.edu. AN - 16942666 AU - Miranda, A. AU - Sood, M. DA - Sep DO - 10.1007/bf02738530 DP - NLM ET - 2006/09/01 IS - 5 LA - eng N1 - Miranda, Adrian Sood, Manu Journal Article United States Curr Treat Options Gastroenterol. 2006 Sep;9(5):409-15. doi: 10.1007/BF02738530. PY - 2006 SN - 1092-8472 (Print) 1092-8472 SP - 409-15 ST - Treatment options for chronic abdominal pain in children and adolescents T2 - Curr Treat Options Gastroenterol TI - Treatment options for chronic abdominal pain in children and adolescents VL - 9 ID - 3995 ER - TY - JOUR AB - Background Paediatric chronic fatigue syndrome or myalgic encephalopathy (CFS/ME) is relatively common and children can be severely affected attending little or no school for extended periods. There are no studies quantifying the financial impact of having a child with CFS/ME and there is little information of the impact on parental mood. Methods Forty mothers of children with CFS/ME from a regional specialist CFS/ME service completed inventories to assess their psychological well-being (Hospital Anxiety and Depression Scale, General Health Questionnaire-12) loss of earnings and increased expenditure. In addition, eight mothers took part in a semi-structured qualitative interview. Results Most parents of children with CFS/ME experience loss of monthly income (mean =247) pound and increase in monthly expenditure (mean =206) pound. Twenty-eight (72%) mothers were above the cut-off for the General Health Questionnaire-12 compared with 20% in the healthy population (95% CI 55, 85, P < 0.001) suggesting they probably have a mental health problem. This may be explained by the qualitative interviews where mothers described five areas contributing to poor parental health: lack of understanding from others; marital tension; concern about their child's distress; concern about the impact on siblings and emotional distress causing physical symptoms. Conclusions The majority of families of children with CFS/ME experience decreased income and increased expenditure with a marked impact on maternal psychological health. Clinicians need to be aware of this to provide appropriate support to families who care for children with CFS/ME. AN - WOS:000304753900008 AU - Missen, A. AU - Hollingworth, W. AU - Eaton, N. AU - Crawley, E. DA - Jul DO - 10.1111/j.1365-2214.2011.01298.x IS - 4 N1 - Missen, A. Hollingworth, W. Eaton, N. Crawley, E. Hollingworth, William/0000-0002-0840-6254 PY - 2012 SN - 0305-1862 SP - 505-512 ST - The financial and psychological impacts on mothers of children with chronic fatigue syndrome (CFS/ME) T2 - Child Care Health and Development TI - The financial and psychological impacts on mothers of children with chronic fatigue syndrome (CFS/ME) UR - ://WOS:000304753900008 VL - 38 ID - 2425 ER - TY - JOUR AB - OBJECTIVE: This update of a 2011 guideline developed by the American Academy of Otolaryngology-Head and Neck Surgery Foundation provides evidence-based recommendations on the pre-, intra-, and postoperative care and management of children 1 to 18 years of age under consideration for tonsillectomy. Tonsillectomy is defined as a surgical procedure performed with or without adenoidectomy that completely removes the tonsil, including its capsule, by dissecting the peritonsillar space between the tonsil capsule and the muscular wall. Tonsillectomy is one of the most common surgical procedures in the United States, with 289,000 ambulatory procedures performed annually in children <15 years of age based on the most recent published data. This guideline is intended for all clinicians in any setting who interact with children who may be candidates for tonsillectomy. PURPOSE: The purpose of this multidisciplinary guideline is to identify quality improvement opportunities in managing children under consideration for tonsillectomy and to create explicit and actionable recommendations to implement these opportunities in clinical practice. Specifically, the goals are to educate clinicians, patients, and/or caregivers regarding the indications for tonsillectomy and the natural history of recurrent throat infections. Additional goals include the following: optimizing the perioperative management of children undergoing tonsillectomy, emphasizing the need for evaluation and intervention in special populations, improving the counseling and education of families who are considering tonsillectomy for their children, highlighting the management options for patients with modifying factors, and reducing inappropriate or unnecessary variations in care. Children aged 1 to 18 years under consideration for tonsillectomy are the target patient for the guideline. For this guideline update, the American Academy of Otolaryngology-Head and Neck Surgery Foundation selected a panel representing the fields of nursing, anesthesiology, consumers, family medicine, infectious disease, otolaryngology-head and neck surgery, pediatrics, and sleep medicine. KEY ACTION STATEMENTS: The guideline update group made strong recommendations for the following key action statements (KASs): (1) Clinicians should recommend watchful waiting for recurrent throat infection if there have been <7 episodes in the past year, <5 episodes per year in the past 2 years, or <3 episodes per year in the past 3 years. (2) Clinicians should administer a single intraoperative dose of intravenous dexamethasone to children undergoing tonsillectomy. (3) Clinicians should recommend ibuprofen, acetaminophen, or both for pain control after tonsillectomy. The guideline update group made recommendations for the following KASs: (1) Clinicians should assess the child with recurrent throat infection who does not meet criteria in KAS 2 for modifying factors that may nonetheless favor tonsillectomy, which may include but are not limited to multiple antibiotic allergies/intolerance, PFAPA (periodic fever, aphthous stomatitis, pharyngitis, and adenitis), or history of >1 peritonsillar abscess. (2) Clinicians should ask caregivers of children with obstructive sleep-disordered breathing and tonsillar hypertrophy about comorbid conditions that may improve after tonsillectomy, including growth retardation, poor school performance, enuresis, asthma, and behavioral problems. (3) Before performing tonsillectomy, the clinician should refer children with obstructive sleep-disordered breathing for polysomnography if they are <2 years of age or if they exhibit any of the following: obesity, Down syndrome, craniofacial abnormalities, neuromuscular disorders, sickle cell disease, or mucopolysaccharidoses. (4) The clinician should advocate for polysomnography prior to tonsillectomy for obstructive sleep-disordered breathing in children without any of the comorbidities listed in KAS 5 for whom the need for tonsillectomy is uncertain or when there is discordance between the physical examination and the reported severity of oSDB. (5) Clinicians should recommend tonsillectomy for children with obstructive sleep apnea documented by overnight polysomnography. (6) Clinicians should counsel patients and caregivers and explain that obstructive sleep-disordered breathing may persist or recur after tonsillectomy and may require further management. (7) The clinician should counsel patients and caregivers regarding the importance of managing posttonsillectomy pain as part of the perioperative education process and should reinforce this counseling at the time of surgery with reminders about the need to anticipate, reassess, and adequately treat pain after surgery. (8) Clinicians should arrange for overnight, inpatient monitoring of children after tonsillectomy if they are <3 years old or have severe obstructive sleep apnea (apnea-hypopnea index ≥10 obstructive events/hour, oxygen saturation nadir <80%, or both). (9) Clinicians should follow up with patients and/or caregivers after tonsillectomy and document in the medical record the presence or absence of bleeding within 24 hours of surgery (primary bleeding) and bleeding occurring later than 24 hours after surgery (secondary bleeding). (10) Clinicians should determine their rate of primary and secondary posttonsillectomy bleeding at least annually. The guideline update group made a strong recommendation against 2 actions: (1) Clinicians should not administer or prescribe perioperative antibiotics to children undergoing tonsillectomy. (2) Clinicians must not administer or prescribe codeine, or any medication containing codeine, after tonsillectomy in children younger than 12 years. The policy level for the recommendation about documenting recurrent throat infection was an option: (1) Clinicians may recommend tonsillectomy for recurrent throat infection with a frequency of at least 7 episodes in the past year, at least 5 episodes per year for 2 years, or at least 3 episodes per year for 3 years with documentation in the medical record for each episode of sore throat and ≥1 of the following: temperature >38.3°C (101°F), cervical adenopathy, tonsillar exudate, or positive test for group A beta-hemolytic streptococcus. DIFFERENCES FROM PRIOR GUIDELINE: (1) Incorporating new evidence profiles to include the role of patient preferences, confidence in the evidence, differences of opinion, quality improvement opportunities, and any exclusion to which the action statement does not apply. (2) There were 1 new clinical practice guideline, 26 new systematic reviews, and 13 new randomized controlled trials included in the current guideline update. (3) Inclusion of 2 consumer advocates on the guideline update group. (4) Changes to 5 KASs from the original guideline: KAS 1 (Watchful waiting for recurrent throat infection), KAS 3 (Tonsillectomy for recurrent infection with modifying factors), KAS 4 (Tonsillectomy for obstructive sleep-disordered breathing), KAS 9 (Perioperative pain counseling), and KAS 10 (Perioperative antibiotics). (5) Seven new KASs: KAS 5 (Indications for polysomnography), KAS 6 (Additional recommendations for polysomnography), KAS 7 (Tonsillectomy for obstructive sleep apnea), KAS 12 (Inpatient monitoring for children after tonsillectomy), KAS 13 (Postoperative ibuprofen and acetaminophen), KAS 14 (Postoperative codeine), and KAS 15a (Outcome assessment for bleeding). (6) Addition of an algorithm outlining KASs. (7) Enhanced emphasis on patient and/or caregiver education and shared decision making. AD - 1 UT Southwestern Medical Center, Dallas, Texas, USA. 2 University of Kentucky, Lexington, Kentucky, USA. 3 Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA. 4 SUNY Downstate Medical Center, Brooklyn, New York, USA. 5 University of Arizona College of Medicine, Phoenix, Arizona, USA. 6 Consumers United for Evidence-based Healthcare, Fredericton, New Brunswick, Canada. 7 Children's Hospital Colorado, Aurora, Colorado, USA. 8 Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA. 9 Yale School of Medicine, New Haven, Connecticut, USA. 10 University of Minnesota School of Medicine, Minneapolis, Minnesota, USA. 11 Mayo Clinic Center for Sleep Medicine, Rochester, Minnesota, USA. 12 Seattle Children's Hospital, Seattle, Washington, USA. 13 Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA. 14 Advocate Children's Hospital, Park Ridge, Illinois, USA. 15 Department of Research and Quality, American Academy of Otolaryngology-Head and Neck Surgery Foundation, Alexandria, Virginia, USA. AN - 30798778 AU - Mitchell, R. B. AU - Archer, S. M. AU - Ishman, S. L. AU - Rosenfeld, R. M. AU - Coles, S. AU - Finestone, S. A. AU - Friedman, N. R. AU - Giordano, T. AU - Hildrew, D. M. AU - Kim, T. W. AU - Lloyd, R. M. AU - Parikh, S. R. AU - Shulman, S. T. AU - Walner, D. L. AU - Walsh, S. A. AU - Nnacheta, L. C. DA - Feb DO - 10.1177/0194599818801757 DP - NLM ET - 2019/02/26 IS - 1_suppl KW - Child Humans Pharyngeal Diseases/*surgery Sleep Apnea, Obstructive/*surgery *Tonsillectomy/adverse effects/methods *adenotonsillectomy *child *obstructive sleep apnea *polysomnography *sleep-disordered breathing *tonsillectomy *tonsillitis LA - eng N1 - 1097-6817 Mitchell, Ron B Archer, Sanford M Ishman, Stacey L Rosenfeld, Richard M Coles, Sarah Finestone, Sandra A Friedman, Norman R Giordano, Terri Hildrew, Douglas M Kim, Tae W Lloyd, Robin M Parikh, Sanjay R Shulman, Stanford T Walner, David L Walsh, Sandra A Nnacheta, Lorraine C Journal Article Practice Guideline Research Support, Non-U.S. Gov't England Otolaryngol Head Neck Surg. 2019 Feb;160(1_suppl):S1-S42. doi: 10.1177/0194599818801757. PY - 2019 SN - 0194-5998 SP - S1-s42 ST - Clinical Practice Guideline: Tonsillectomy in Children (Update) T2 - Otolaryngol Head Neck Surg TI - Clinical Practice Guideline: Tonsillectomy in Children (Update) VL - 160 ID - 4067 ER - TY - JOUR AB - Objectives: This study used semiology based on traditional Chinese medicine (TCM) to investigate vital energy (Qi) behavior in women with abdominal myofascial pain syndrome (AMPS). Methods: Fifty women diagnosed with chronic pelvic pain (CPP) secondary to AMPS were evaluated by using a questionnaire based on the theories of "yin-yang," "zang-fu", and "five elements". We assessed the following aspects of the illness: symptomatology; specific location of myofascial trigger points (MTrPs); onset, cause, duration and frequency of symptoms; and patient and family history. The patients tongues, lips, skin colors, and tones of speech were examined. Patients were questioned on various aspects related to breathing, sweating, sleep quality, emotions, and preferences related to color, food, flavors, and weather or seasons. Thirst, gastrointestinal dysfunction, excreta (feces and urine), menstrual cycle, the five senses, and characteristic pain symptoms related to headache, musculoskeletal pain, abdomen, and chest were also investigated. Results: Patients were between 22 and 56 years old, and most were married (78%), possessed a elementary school (66%), and had one or two children (76%). The mean body mass index and body fat were 26.86 kg/cm2 (range: 17.7 - 39.0) and 32.4% (range: 10.7 - 45.7), respectively. A large majority of women (96%) exhibited alterations in the kidney meridian, and 98% had an altered gallbladder meridian. We observed major changes in the kidney and the gallbladder Qi meridians in 76% and 62% of patients, respectively. Five of the twelve meridians analyzed exhibited Qi patterns similar to pelvic innervation Qi and meridians, indicating that the paths of some of these meridians were directly related to innervation of the pelvic floor and abdominal region. Conclusion: The women in this study showed changes in the behavior of the energy meridians, and the paths of some of the meridians were directly related to innervation of the pelvic floor and abdominal region. AN - WOS:000383280300004 AU - Mitidieri, A. AU - Gurian, M. B. AU - Silva, A. P. AU - Tawasha, K. AU - Poli-Neto, O. AU - Nogueira, A. AU - Reis, F. AU - Rosa-e-Silva, J. DA - Dec DO - 10.3831/kpi.2015.18.034 IS - 4 N1 - Mitidieri, Andreia Gurian, Maria Beatriz Silva, Ana Paula Tawasha, Kalil Poli-Neto, Omero Nogueira, Antonio Reis, Francisco Rosa-e-Silva, Julio Poli-Neto, Omero Benedicto/E-1392-2012 Poli-Neto, Omero Benedicto/0000-0003-0270-5496 2234-6856 PY - 2015 SN - 2093-6966 SP - 26-31 ST - Evaluation of Women with Myofascial Abdominal Syndrome Based on Traditional Chinese Medicine T2 - Journal of Pharmacopuncture TI - Evaluation of Women with Myofascial Abdominal Syndrome Based on Traditional Chinese Medicine UR - ://WOS:000383280300004 VL - 18 ID - 2200 ER - TY - JOUR AB - Purpose: To understand the experience of adolescent systemic juvenile idiopathic arthritis (SJIA) patients and those of their parents based on their social media posts. Methods: English language posts related to SJIA, Still's disease, or juvenile arthritis were collected and analyzed. Results: In total, 71 posts created between 2009 and 2015 on 15 websites were identified in November 2015. Of the 32 unique authors, 17 were SJIA patients aged 13-20 years (40 posts), 7 were mothers of SJIA patients (12 posts), and 8 patients had unspecified forms of juvenile arthritis (19 posts). Many patients posted about similar diagnostic experiences marked by 5 phases: 1) early prediagnosis: pain and fatigue overlooked until crisis occurred, 2) first misdiagnosis: doctors talked about "growing pains" and psychosocial problems ("fake pains" to avoid school), 3) second misdiagnosis: severity acknowledged, but diagnosed as leukemia or another cancer, 4) tests: tests leading to diagnosis and treatment conducted, and 5) cognitive identity: patient accepted the diagnosis and its implications. Many adolescent patients, looking back at disease onset in their childhood, described themselves as a "sleeping child" rather than the typical active child. Several patients tried to hide their illness from friends, but expressed concerns openly online. Many patients described SJIA as a powerful external enemy, using terms like "bulldozer," "dragon," and " monster. "Many posts from patients and their mothers used superhero language/imagery to help "fight" SJIA. Some patients also posted about the risk of death. Conclusion: Although most adolescent SJIA patients openly posted about the difficulties of their disease online, they made efforts to hide their disease in the real world. They frequently used superhero words and images in describing their fight for better health. Physicians can use these insights when counseling SJIA patients to provide a narrative that meshes with the patients' worldview and perhaps to improve physician-patient communication to increase treatment adherence. AN - WOS:000435068800001 AU - Modica, R. F. AU - Lomax, K. G. AU - Batzel, P. AU - Cassanas, A. DO - 10.2147/oarrr.S165010 N1 - Modica, Renee F. Lomax, Kathleen G. Batzel, Pamela Cassanas, Armelle lomax, kathleen/0000-0003-4519-3240 PY - 2018 SN - 1179-156X SP - 73-81 ST - Impact of systemic juvenile idiopathic arthritis/Still's disease on adolescents as evidenced through social media posts T2 - Open Access Rheumatology-Research and Reviews TI - Impact of systemic juvenile idiopathic arthritis/Still's disease on adolescents as evidenced through social media posts UR - ://WOS:000435068800001 VL - 10 ID - 2051 ER - TY - JOUR AB - OBJECTIVE: To study the association between socio-economic factors, lifestyle habits, and self-reported recurrent headache/migraine (RH/M) in a general population. METHODS: The study population comprised a random sample of men and women aged 18-79 years. The data were obtained using a postal survey questionnaire during March-May 2000. The overall response rate was 65%. The area investigated covers 58 municipalities with about one million inhabitants in central part of Sweden. The study is based on 43,770 respondents. Odds ratios for RH/M were calculated for a set of variables using multiple logistic regression models. RESULTS: The overall prevalence of self-reported RH/M during the last 3 months was 10% among men and 23% among women and decreased with increasing age. Physically inactive subjects were more likely to suffer from headache disorders than physically active subjects. Smoking was only moderately associated with RH/M. There was an inverse relationship between heavy alcohol use and RH/M. Underweight and obesity were not associated with headache disorders when adjusted for socio-economic factors. Subjects with frequent economic problems had almost twice the risk of RH/M compared with subjects with no economic problems. Poor social support was associated with headache disorders and subjects who had been belittled during the last 3 months were more than twice as likely to suffer from RH/M as subjects who had not been belittled. The effect of educational level was modest. Marital status and country of origin were not associated with headache disorders after adjustment for other socio-economic factors. Dissatisfaction with work, worry about losing one's job, and absenteeism due to illness were strongly associated with headache disorders. Physical working conditions and working hours were not associated with RH/M. CONCLUSION: Headache disorders mainly affect young and middle-aged adults. There are, however, socio-economic disparities in self-reported recurrent headache and migraine. The relationship was particularly evident for economic hardship and psychosocial factors. Of lifestyle factors, physical inactivity was strongly associated with headache disorders independent of economic and psychosocial factors. AD - Västmanland County Council, Department of Community Medicine, Västerås, Sweden. AN - 18624712 AU - Molarius, A. AU - Tegelberg, A. AU - Ohrvik, J. DA - Nov-Dec DO - 10.1111/j.1526-4610.2008.01178.x DP - NLM ET - 2008/07/16 IS - 10 KW - Adolescent Adult Age Factors Aged Cohort Studies Female Headache Disorders/*epidemiology Health Status Humans Life Style Logistic Models Male Middle Aged Prevalence Psychology Risk Factors Risk Reduction Behavior Self-Assessment Socioeconomic Factors *Surveys and Questionnaires Sweden/epidemiology LA - eng N1 - 1526-4610 Molarius, Anu Tegelberg, Ake Ohrvik, John Journal Article Research Support, Non-U.S. Gov't United States Headache. 2008 Nov-Dec;48(10):1426-37. doi: 10.1111/j.1526-4610.2008.01178.x. Epub 2008 Jul 1. PY - 2008 SN - 0017-8748 SP - 1426-37 ST - Socio-economic factors, lifestyle, and headache disorders - a population-based study in Sweden T2 - Headache TI - Socio-economic factors, lifestyle, and headache disorders - a population-based study in Sweden VL - 48 ID - 3726 ER - TY - JOUR AB - Background: Aggressive treatment protocols in pediatric oncology have major effects on the lives of children with cancer. The effects of lifestyle changes such as hospitalization and home schooling on quality of life have not been investigated. This study explores lifestyle effects of cancer therapy on the quality of life of children with cancer. The goals of this study were to identify important quality-of-life issues from the perspectives of children with cancer and to identify how they think their experience with cancer treatment could be improved. Materials and methods: Pediatric oncology patients age 5-21 were interviewed individually. Sample questions included, "Ever since you got sick, what has bothered you the most?" and "How has having this illness affected your life?" Responses were analyzed using standard qualitative techniques. Results: Thirty-one patients were interviewed in depth. Four major themes emerged including (1) loneliness and isolation: the loss of a normal childhood, (2) decreased pleasure from food, (3) physical discomfort and disability, and (4) emotional responses to cancer, specifically anger and fear. Their suggestions for improvement included better-tasting food, more comfortable hospital decor, and social activities with children their own age. Conclusions: Children cited concerns regarding pleasures taken away as well as pain inflicted due to cancer treatment. In addition to traditionally mentioned side effects, children complained of difficulty enjoying food and restricted social activity. To improve the quality of life of children with cancer, healthcare providers should focus on potentially modifiable variables including food-related pleasure, hospital aesthetics, and social activity. AN - WOS:000239812300010 AU - Moody, K. AU - Meyer, M. AU - Mancuso, C. A. AU - Charlson, M. AU - Robbins, L. DA - Sep DO - 10.1007/s00520-006-0024-y IS - 9 N1 - Moody, Karen Meyer, Marc Mancuso, Carol A. Charlson, Mary Robbins, Laura Conference of the Society-for-Clinical-Epidemiology-and-Health-Services-Research May-oct -, 2002-2003 San Diego, CA Soc Clin Epidemiol & Hlth Serv Res 1433-7339 PY - 2006 SN - 0941-4355 SP - 960-966 ST - Exploring concerns of children with cancer T2 - Supportive Care in Cancer TI - Exploring concerns of children with cancer UR - ://WOS:000239812300010 VL - 14 ID - 2722 ER - TY - JOUR AB - Juvenile arthritis comprises a variety of chronic inflammatory diseases causing erosive arthritis in children, often progressing to disability. These children experience functional impairment due to joint and back pain, heel pain, swelling of joints and morning stiffness, contractures, pain, and anterior uveitis leading to blindness. As children who have juvenile arthritis reach adulthood, they face possible continuing disease activity, medication-associated morbidity, and life-long disability and risk for emotional and social dysfunction. In this article we will review the burden of juvenile arthritis for the patient and society and focus on the following areas: patient disability; visual outcome; other medical complications; physical activity; impact on HRQOL; emotional impact; pain and coping; ambulatory visits, hospitalizations and mortality; economic impact; burden on caregivers; transition issues; educational occupational outcomes, and sexuality. The extent of impact on the various aspects of the patients', families' and society's functioning is clear from the existing literature. Juvenile arthritis imposes a significant burden on different spheres of the patients', caregivers' and family's life. In addition, it imposes a societal burden of significant health care costs and utilization. Juvenile arthritis affects health-related quality of life, physical function and visual outcome of children and impacts functioning in school and home. Effective, well-designed and appropriately tailored interventions are required to improve transitioning to adult care, encourage future vocation/occupation, enhance school function and minimize burden on costs. AN - WOS:000282502500001 AU - Moorthy, L. N. AU - Peterson, M. G. E. AU - Hassett, A. L. AU - Lehman, T. J. A. C7 - 20 DA - Jul DO - 10.1186/1546-0096-8-20 N1 - Moorthy, Lakshmi N. Peterson, Margaret G. E. Hassett, Afton L. Lehman, Thomas J. A. PY - 2010 SN - 1546-0096 ST - Burden of childhood-onset arthritis T2 - Pediatric Rheumatology TI - Burden of childhood-onset arthritis UR - ://WOS:000282502500001 VL - 8 ID - 2544 ER - TY - JOUR AB - The aim of the study was to investigate the burden of mental health problems in children and adolescents admitted to a pediatric ward with physical complaints. We conducted a retrospective study, considering all patients admitted to the pediatric ward of the IRCCS Burlo Garofolo, Trieste, Italy, between January 2015 and September 2016. We selected all patients, from 5 to 17 years old, who were admitted with physical complaints and were discharged with a diagnosis suggestive of a mental health problem: somatic symptom disorder, anxiety disorder, depressive disorder, factious disorders. For every patient, we collected demographic features, medical characteristics, health care services utilization, length of hospital stay, and after discharge referral. We selected 1456 patients; of these, 101 (6.9%) revealed a mental health problem. The median duration of symptoms was 5 months (IQR 1.5-12), and pain was the main reported symptom (69%). Of the 101 patients, 23 (23%) were affected by a previously documented chronic organic disease. Somatic symptom disorder was the most common diagnosis. In 69/78 patients (88%), a loss of social contacts emerged; 49/95 patients frequenting school (51%) had chronic school absenteeism in the previous school year. Conclusion: A considerable proportion of patients admitted to a pediatric ward with physical complaints have mental health problems. What is Known: center dot It has been suggested that mental health problems in children and adolescents are increasing and frequently burden on pediatric healthcare services, but how they impact on a general pediatric ward is not clear. What is New: center dot Among 1456 patients admitted to a general pediatric ward with physical symptoms, 101 patients (6.9%) had a mental health problem. Among them, pain was the most commonly reported symptom and somatic symptom disorder was the commonly reported diagnosis. AN - WOS:000608929900005 AU - Morabito, G. AU - Barbi, E. AU - Ghirardo, S. AU - Bramuzzo, M. AU - Conversano, E. AU - Ventura, A. AU - Cozzi, G. DA - May DO - 10.1007/s00431-021-03938-y IS - 5 N1 - Morabito, Giuliana Barbi, Egidio Ghirardo, Sergio Bramuzzo, Matteo Conversano, Ester Ventura, Alessandro Cozzi, Giorgio Barbi, Egidio/K-4016-2018 Barbi, Egidio/0000-0002-6343-846X 1432-1076 PY - 2021 SN - 0340-6199 SP - 1611-1615 ST - Mental health problems in children admitted with physical symptoms T2 - European Journal of Pediatrics TI - Mental health problems in children admitted with physical symptoms UR - ://WOS:000608929900005 VL - 180 ID - 1763 ER - TY - JOUR AB - BACKGROUND: The assessment of the functionality of intrathecal drug delivery (IDD) systems remains difficult and time-consuming. Catheter-related problems are still very common, and sometimes difficult to diagnose. OBJECTIVES: The aim of the present study is to investigate the accuracy of high-resolution three-dimensional computed tomography (CT) in order to detect catheter-related pump dysfunction. STUDY DESIGN: An observational, retrospective investigation. SETTING: Academic medical center in Germany. METHODS: We used high-resolution three dimensional (3D) computed tomography with volume rendering technique (VRT) or fluoroscopy and conventional axial-CT to assess IDD-related complications in 51 patients from our institution who had IDD systems implanted for the treatment of chronic pain or spasticity. RESULTS: Twelve patients (23.5%) presented a total of 22 complications. The main type of complication in our series was catheter-related (50%), followed by pump failure, infection, and inappropriate refilling. Fluoroscopy and conventional CT were used in 12 cases. High-resolution 3D CT VRT scan was used in 35 instances with suspected yet unclear complications. Using 3D-CT (VRT) the sensitivity was 58.93% - 100% (CI 95%) and the specificity 87.54% - 100% (CI 95%).The positive predictive value was 58.93% - 100% (CI 95%) and the negative predictive value: 87.54% - 100% (CI 95%).Fluoroscopy and axial CT as a combined diagnostic tool had a sensitivity of 8.3% - 91.7% (CI 95%) and a specificity of 62.9% - 100% (CI 95%). The positive predictive value was 19.29% - 100% (CI 95%) and the negative predictive value: 44.43% - 96.89% (CI 95%). LIMITATIONS: This study is limited by its observational design and the small number of cases. CONCLUSION: High-resolution 3D CT VRT is a non- invasive method that can identify IDD-related complications with more precision than axial CT and fluoroscopy. AD - University of Tuebingen, University Hospital, Dept. of Neurosurgery, Tuebingen, Germany. AN - 27389121 AU - Morgalla, M. AU - Fortunato, M. AU - Azam, A. AU - Tatagiba, M. AU - Lepski, G. DA - Jul DP - NLM ET - 2016/07/09 IS - 5 KW - Adolescent Adult Aged Catheters/*adverse effects Chronic Pain/drug therapy Female Germany Humans Imaging, Three-Dimensional/*standards Infusion Pumps/*adverse effects Infusions, Spinal/*adverse effects Male Middle Aged Muscle Spasticity/drug therapy Postoperative Complications/*diagnostic imaging Predictive Value of Tests Retrospective Studies Sensitivity and Specificity Tomography, X-Ray Computed/*standards Young Adult LA - eng N1 - 2150-1149 Morgalla, Matthias Fortunato, Marcos Azam, Ala Tatagiba, Marcos Lepski, Guillherme Journal Article Observational Study United States Pain Physician. 2016 Jul;19(5):E775-80. PY - 2016 SN - 1533-3159 SP - E775-80 ST - High-Resolution Three-Dimensional Computed Tomography for Assessing Complications Related to Intrathecal Drug Delivery T2 - Pain Physician TI - High-Resolution Three-Dimensional Computed Tomography for Assessing Complications Related to Intrathecal Drug Delivery VL - 19 ID - 3725 ER - TY - JOUR AB - The aim of this study was to estimate the chaos phenomenon (chaos) in masticatory movements using the fractal dimension (FD), and to examine the diagnostic value of the fractal dimension in comparing stomatognathic functional disturbances with normal stomatognathic function. The subjects were all high school students and included nine subjects presenting with acceptable normal occlusion, 18 subjects with TMJ dysfunction syndrome and seven subjects with tooth crowding. Masticatory movements were obtained during free, right side, and left side gum-chewing and were used to calculate the capacity dimension in the FD. Chaos in the masticatory movement was estimated by the FD saturated with some constant value to an increase of embedding dimension (approached a plateau). In the crowding group, the FD was also significantly high on the sagittal plane in comparison with the normal. In the patients with pain, the FD on the sagittal plane was significantly high. In the patients with pain and closed lock, the FD on the frontal plane was significantly high. However, in the patients with pain and with reduction of anterior disc displacement, the FD was significantly low on the horizontal plane. These findings suggest that chaos is present in masticatory movements and the difference in the FD are of diagnostic value in evaluation of the relationship between FD and stomatognathic functional disturbance. AD - Department of Pediatric Dentistry, Kagoshima University Dental School, Sakuragaoka, Japan. AN - 9639164 AU - Morinushi, T. AU - Kawasaki, H. AU - Masumoto, Y. AU - Shigeta, K. AU - Ogura, T. AU - Takigawa, M. DA - May DO - 10.1046/j.1365-2842.1998.00230.x DP - NLM ET - 1998/06/25 IS - 5 KW - Adolescent Facial Pain/physiopathology Female Fractals Humans Magnetic Resonance Imaging Male Malocclusion/*physiopathology Mastication/*physiology Models, Biological *Nonlinear Dynamics Reference Values Temporomandibular Joint Dysfunction Syndrome/*physiopathology LA - eng N1 - Morinushi, T Kawasaki, H Masumoto, Y Shigeta, K Ogura, T Takigawa, M Journal Article England J Oral Rehabil. 1998 May;25(5):386-94. doi: 10.1046/j.1365-2842.1998.00230.x. PY - 1998 SN - 0305-182X (Print) 0305-182x SP - 386-94 ST - Examination of the diagnostic value and estimation of the chaos phenomenon in masticatory movement using fractal dimension in patients with temporomandibular dysfunction syndrome T2 - J Oral Rehabil TI - Examination of the diagnostic value and estimation of the chaos phenomenon in masticatory movement using fractal dimension in patients with temporomandibular dysfunction syndrome VL - 25 ID - 3694 ER - TY - JOUR AB - Purpose: Children with medical complexity (MC) must rely on others to notice and address pain. Parents are aware of child pain behaviors and can serve as reliable proxy reporters. Thus, there is a critical need to understand parent perspectives to improve pain practices. Design: Individual interviews were used as a data collection method in this qualitative study. Methods: Participants were recruited via mail and social media postings. Interviews were audio-recorded and transcribed verbatim. Transcribed documents were imported to NVIVO for qualitative analysis. Conventional and directed approaches to qualitative content analysis were used. Results: From the data analysis, major themes included: pain experiences, confidence in caregivers, parents are partners, proactive communication, and a spontaneous theme, "they can hear us." Emotional pain and challenges identifying the source pain were identified as sub-themes of pain experiences. Conclusions: Parents in this study shared methods helpful to identifying pain in their children, as well as suggestions for discussing pain with caregivers. Priorities for future research include identifying methods for sharing pain information that are thorough, but do not burden parents or providers. Researchers should also determine how parents and caregivers can partner to identify and address pain in children with MC. Going forward, conversations about pain should be a key part of any admission assessment or first encounter. As pain episodes among children with MC can be complex and may not always be recreated in front of a provider, nurses may advise parents to take photos or videos to share with caregivers. (C) 2020 American Society for Pain Management Nursing. Published by Elsevier Inc. All rights reserved. AN - WOS:000651411100009 AU - Morse, B. L. AU - Serna, R. W. AU - LaLumiere, M. AU - Rogal, M. AU - Foley, K. AU - Lombardo, M. AU - Manganello, C. AU - Pugh, V. AU - Veloz, A. AU - Solodiuk, J. C. AU - Mauskar, S. DA - Apr DO - 10.1016/j.pmn.2020.11.011 IS - 2 N1 - Morse, Brenna L. Serna, Richard W. LaLumiere, McKenzie Rogal, Micaela Foley, Kerri Lombardo, Miranda Manganello, Christopher Pugh, Victoria Veloz, Amy Solodiuk, Jean C. Mauskar, Sangeeta 1532-8635 PY - 2021 SN - 1524-9042 SP - 169-176 ST - Leveraging Parent Pain Perspectives to Improve Pain Practices for Children with Medical Complexity T2 - Pain Management Nursing TI - Leveraging Parent Pain Perspectives to Improve Pain Practices for Children with Medical Complexity UR - ://WOS:000651411100009 VL - 22 ID - 1741 ER - TY - JOUR AB - Background and Purpose. Lyme disease is well documented in the literature; however, specific physical therapy interventions for the pediatric population with residual effects of Lyme disease have not been addressed. The purposes of this retrospective case report are: (1) to present an example of a therapeutic intervention for a pediatric patient in the late stages of Lyme disease with related musculoskeletal dysfunction and severely impaired quality of life, (2) to report the patient's functional outcomes from treatment, and (3) to discuss implications for treatment of patients with musculoskeletal dysfunction in the late stages of Lyme disease. Case Description. The patient was a 14-year old girl who had contracted Lyme disease 1 year prior to initiation of physical therapy. She was unable to participate with her peers in school, church, and sporting events due to significant impairments in strength (force-generating capacity), endurance, and gait; fatigue; pain; and total body tremor. Therapeutic exercise and gait training were used for treatment. The patient actively participated in managing her care by providing feedback during interventions and setting goals. Outcomes. After 18 weeks of treatment, the patient achieved 96.7% of her predicted distance on the Six-Minute Walk Test with normal gait mechanics and returned to playing high school sports. She had a manual muscle test grade of 4/5 or greater in major extremity muscle groups. She returned to school and church participation with minimal total body tremor when fatigued and daily pain rated 0 to 3/10. Discussion. Therapeutic exercise and gait training may facilitate return to function in an adolescent patient with late effects of Lyme disease. Further investigation is advised to establish treatment effects in a broader population. AN - WOS:000294461600011 AU - Moser, M. M. C. DA - Sep DO - 10.2522/ptj.20110020 IS - 9 N1 - Moser, Myriam M. C. 1538-6724 PY - 2011 SN - 0031-9023 SP - 1412-1423 ST - Treatment for a 14-Year-Old Girl With Lyme Disease Using Therapeutic Exercise and Gait Training T2 - Physical Therapy TI - Treatment for a 14-Year-Old Girl With Lyme Disease Using Therapeutic Exercise and Gait Training UR - ://WOS:000294461600011 VL - 91 ID - 2480 ER - TY - JOUR AB - Objectives The purpose of this study was to develop a comprehensive back school program that included elements of CBT (Cognitive Behavioral Therapy), implement this through multidisciplinary collaboration, and ascertain its effectiveness as a pilot study. Design This school was implemented in the form of five 90-minute group sessions held every other week. Methods Participants comprised 7 chronic low back pain patients with poor improvement in the usual treatment. Practitioners were orthopaedic surgeon, physical therapist, and a clinical psychologist. This school contents were patient education, self-monitoring, back exercise, relaxation, stress man- agement, cognitive restructuring, activity pacing, and exposure. Results From the Wilcoxon signed rank test, each score of four scales or items (sense of control, PCS (pain catastrophizing), PASS 20 (escape/avoidance), FFD (finger floor distance)) after this program significantly improved. Results of calculating the effect size, sense of control (d=0.55) is 'moderate', the PCS (d =1.12) and the PASS 20 (d=1.64) were 'large'. Conclusions This back school may be useful for physical function and psychological variables which much related to pain management and daily disabilities in patients with poor respond to standard orthopaedic treatment. AN - WOS:000432424700007 AU - Motoya, R. AU - Otani, K. AU - Nikaido, T. AU - Ono, Y. AU - Matsumoto, T. AU - Yamagishi, R. AU - Yabuki, S. AU - Konno, S. I. AU - Niwa, S. I. AU - Yabe, H. DA - Aug DO - 10.5387/fms.2016-07 IS - 2 N1 - Motoya, Ryo Otani, Koji Nikaido, Takuya Ono, Yoko Matsumoto, Takatomo Yamagishi, Ryohei Yabuki, Shoji Konno, Shin-Ichi Niwa, Shin-Ichi Yabe, Hirooki Otani, Koji/ABF-8564-2020 Otani, Koji/0000-0001-8409-9623 2185-4610 PY - 2017 SN - 0016-2590 SP - 81-89 ST - Short-term effect of back school based on cognitive behavioral therapy involving multidisciplinary collaboration T2 - Fukushima Journal of Medical Science TI - Short-term effect of back school based on cognitive behavioral therapy involving multidisciplinary collaboration UR - ://WOS:000432424700007 VL - 63 ID - 2081 ER - TY - JOUR AB - The objective of this study was to determine the prevalence of migraine and its impact in a working population. A random sample of 476 employees in a chemical industry research and commercial centre took part in this cross-sectional questionnaire-based study. The questionnaire assessed the past-year prevalence of migraine, frequency and duration of episodes, effect on work and sickness absence, use and efficacy of medication and possible 'trigger factors'. Migraine prevalence was 23.2% in women and 11.6% in men. Migraineurs reported significantly more headache-related sickness absence, but did not have significantly more recorded sickness absence overall than did non-migraineurs. Of the migraineurs, 42% had never sought medical advice regarding headaches and most used non-prescription medication. Migraine is common in the study population, resulting in sickness absence and work disruption, although migraineurs have little if any more sickness absence than others. Migraineurs' use of medication is sub-optimal, and occupational health departments could assist them with education and advice. AD - ICI Chemicals and Polymers Ltd, Middlesborough, Cleveland, UK. AN - 8580474 AU - Mounstephen, A. H. AU - Harrison, R. K. DA - Dec DO - 10.1093/occmed/45.6.311 DP - NLM ET - 1995/12/01 IS - 6 KW - Absenteeism Adolescent Adult Cross-Sectional Studies England/epidemiology Female Humans Male Middle Aged Migraine Disorders/drug therapy/*epidemiology Occupational Diseases/drug therapy/*epidemiology Patient Education as Topic Prevalence LA - eng N1 - Mounstephen, A H Harrison, R K Comment Journal Article England Occup Med (Lond). 1995 Dec;45(6):311-7. doi: 10.1093/occmed/45.6.311. PY - 1995 SN - 0962-7480 (Print) 0962-7480 SP - 311-7 ST - A study of migraine and its effects in a working population T2 - Occup Med (Lond) TI - A study of migraine and its effects in a working population VL - 45 ID - 3411 ER - TY - JOUR AB - Twenty-four percent of the Gabonese population has sickle cell trait, and 1-3% has sickle cell disease. Patients' management must follow well-defined protocols that take into account the debilitating effect of severe pain episodes. Objectives. - To evaluate the three-step analgesic ladder for control of pain for sickle cell disease pain crises. Methodology. - This is a prospective and descriptive study based on surveys filled between February 2000 and March 2001. Surveys were restricted to sickle cell disease patients having developed pain crises before and during their stay at the hospital. The assessment of the pain was based on the DEGR and EVA scales. The treatment followed the World Health Organisation's analgesic ladder. The criteria used for estimate pain severity and sedation duration were measured before, 2 and 24 It after treatment administration began (H0, H2 and H24) to evaluate its effectiveness. Results. - Sixty children were included. All the social layers of the population were represented. The school level was variable. Fifty-six percent of the patients suffered their first pain crisis before they were 1 year old. Thirty-one percent had annual crises and 20% monthly crises. Pain was located in joints in 35% of the cases, and in joints and bones in 15% of the cases. Eighty-one percent of the pain crises were successfully treated in stage I. The passage to stage II occurred in the remaining cases (18.3% of the cases). AN - WOS:000224211000003 AU - Moussavou, A. AU - Vierin, Y. AU - Eloundou-Orima, C. AU - Mboussou, A. AU - Keita, M. DA - Sep DO - 10.1016/j.arcped.2004.03.100 IS - 9 N1 - Moussavou, A Vierin, Y Eloundou-Orima, C Mboussou, A Keita, M PY - 2004 SN - 0929-693X SP - 1041-1045 ST - Sickle cell disease pain management following the World Health Organization's protocol T2 - Archives De Pediatrie TI - Sickle cell disease pain management following the World Health Organization's protocol UR - ://WOS:000224211000003 VL - 11 ID - 2785 ER - TY - JOUR AB - Recurrent abdominal pain (RAP) is one of the most common pain syndromes in childhood, with prevalence rates ranging from 10 to 20% in all school-age children. In nearly 50% the complaints persist over many years of their life-span to adolescence or adulthood. Although the empirical findings have increased in the last decade, our knowledge about the etiology, pathogenesis, and pathophysiology is still very limited. Current approaches suggest that we understand recurrent pain syndromes as a complex and multidimensional disturbance (biopsychosocial paradigm). In this respect there is strong evidence for the major importance of psychosocial causes (daily hassles, specific rife events), psychopathological factors (anxiety, depression, somatization disorder), and social environmental influences (mother's psychopathology, social modelling, reinforcement) in the pathogenesis of functional abdominal pain. The noticeable correlation with other pain syndromes and functional disturbances indicates that recurrent pain may possibly be a manifestation of a basic somatization disorder. The unfavourable long-term prognosis supports the need for early and specific interventions. Psychological treatment requires a medical examination to exclude organic origins. Some of these invasive diagnostic procedures can be Very difficult expensive and distressing for the child. Behavioural medicine is based upon having an extensive family history and symptom analysis. The psychological interventions applied in clinical practice include prophylaxis, reduction of pain symptoms and environmental modification. In recent years there has been an increasing trend to create more complex and multidimensional behavioural treatment programs for children. Although preliminary data on the use of these behavioural medicine programs have shown some promise, further investigations are needed to examine the applicability and effectiveness of specific interventions in the treatment of abdominal pain symptoms. AN - WOS:A1997XF84800002 AU - Muhlig, S. AU - Petermann, F. DA - May DO - 10.1007/s004820050078 IS - 3 N1 - Muhlig, S Petermann, F PY - 1997 SN - 0932-433X SP - 148-157 ST - Idiopathic abdominal pain in children: Results, deficits and perspectives of empirical research T2 - Schmerz TI - Idiopathic abdominal pain in children: Results, deficits and perspectives of empirical research UR - ://WOS:A1997XF84800002 VL - 11 ID - 2911 ER - TY - JOUR AB - Background: The primary causes of low back pain vary and are often difficult to identify which limits the prevention of its first incidence. The modification of known risk factors can only prevent the occurrence to a certain extent. However, there is the possibility to control the consequences of low back pain, such as recurrence rate, care seeking, disability degree and loss of work. Objective: The article summarizes the European Guidelines - Prevention of Low Back Pain. The guidelines represent the results of a literature research in different data bases with view to the topic Prevention of back pain in a wide sense. Methods: The literature investigation emloyed detailed searching strategies. Then the articles were compiled in thematic groups and evaluated. In this the focus was set on recommendations for general and working population. The evidence for physiotherapeutically relevant interventions are recorded in more detail, i.e. kinesitherapy, manual therapy and information. The evidence for orthopedically affected interventions (shoe insoles, pelvis belts, furniture, organisational dimensions) as well as for the prevention of back pain in school age is portrayed in form of short recommendations. Results: The most promising approaches seem to involve physical activity/ exercise and appropriate (biopsychosocial) education (at least for adults). However the effect sizes of the interventions with acceptable evidence are rather modest. In addition, no single intervention is likely to be effective to prevent the overall problem of LBP, owing to its multidimensional nature. Individuals may constantly report of helpful strategies, which with view to the absence of scientific evidence of their preventive effect cannot be recommended in general. It is also not known whether some of these strategies have negative long-term effects. Conclusions: Prevention of LBP is a societal as well as an individual concern. In order to achieve optimum progress a shift of the society's view concerning the attitude towards LBP is required. Above all it is necessary to rethink the relationship between back pain and activity/work, how back pain might best be tackled, and what is reasonable to expect from preventive strategies. AN - WOS:000217816600002 AU - Muller, G. AU - Burton, A. K. AU - Balague, F. AU - Cardon, G. AU - Eriksen, H. R. AU - Henrotin, Y. AU - Lahad, A. AU - Leclerc, A. AU - van der Beek, A. J. DA - Nov DO - 10.1055/s-2005-858693 IS - 3 N1 - Mueller, G. Burton, A. K. Balague, F. Cardon, G. Eriksen, H. R. Henrotin, Y. Lahad, A. Leclerc, A. van der Beek, A. J. 1860-3351 PY - 2005 SN - 1860-3092 SP - 100-112 ST - Evidence of the Efficacy of Preventive Means for Low Back Pain European Guidelines T2 - Physioscience TI - Evidence of the Efficacy of Preventive Means for Low Back Pain European Guidelines UR - ://WOS:000217816600002 VL - 1 ID - 2751 ER - TY - JOUR AB - OBJECTIVES: The high life-time prevalence of chronic back pain (25-30% according to surveys in small samples) suggests that it may be a major source of healthcare cost and that prevention of chronic back pain may be both ethically and economically recommendable. To obtain valid economic data on the cost of back pain in Germany, a retrospective claims data analysis was performed. METHODS: Using data from 2006 of 5.2 million beneficiaries of a German statutory health insurance fund (DAK Unternehmen Leben) covering ~7% of the German population, mean value analyses report on key healthcare utilization figures from a sickness funds? perspective. In contrast to other studies, cost data are primary data and not extrapolated, but clinical characteristics include surrogate markers as no clinical case descriptions were available. RESULTS: Based on previously investigated diagnosis patterns three types of back pain could be identified: (other) specific back pain (n=211,216), pain due to spinal disk disease (n=195,712), and non-specific back pain (n=534,272). Of all back pain patients, 25.8% were identified as at risk to develop chronic pain, where only 2.6% were detected as patients with chronic back pain. Mean resource utilization and related healthcare costs were significantly higher for beneficiaries with indicators for chronic back pain than for beneficiaries with only risk factors for developing chronic back pain. This especially holds for outpatient analgesic prescriptions (p<0.05), for in-hospital multimodal pain therapy (p<0.05), for in-hospital care in general (p<0.05), as well as for direct cost of care (p<0.05). CONCLUSION: The results show the potential that could be made accessible by an early detection of back pain patients who bear a risk of pain becoming chronic, both in terms of quality-of-life as well as in financial terms. AD - German Society for Pain Therapy e.V. (DGS), Oberursel, Germany. AN - 21992218 AU - Müller-Schwefe, G. AU - Freytag, A. AU - Höer, A. AU - Schiffhorst, G. AU - Becker, A. AU - Casser, H. R. AU - Glaeske, G. AU - Thoma, R. AU - Treede, R. D. DO - 10.3111/13696998.2011.625067 DP - NLM ET - 2011/10/14 IS - 6 KW - Absenteeism Adolescent Adult Aged Back Pain/*economics/therapy Child Child, Preschool Chronic Disease Cost of Illness Female Germany Health Services/*economics/*statistics & numerical data Humans Insurance Claim Review/statistics & numerical data Male Middle Aged Retrospective Studies Risk Factors Spinal Diseases/economics/therapy Young Adult LA - eng N1 - 1941-837x Müller-Schwefe, G Freytag, A Höer, A Schiffhorst, G Becker, A Casser, H-R Glaeske, G Thoma, R Treede, R-D Journal Article Research Support, Non-U.S. Gov't England J Med Econ. 2011;14(6):816-23. doi: 10.3111/13696998.2011.625067. Epub 2011 Oct 12. PY - 2011 SN - 1369-6998 SP - 816-23 ST - Healthcare utilization of back pain patients: results of a claims data analysis T2 - J Med Econ TI - Healthcare utilization of back pain patients: results of a claims data analysis VL - 14 ID - 3193 ER - TY - JOUR AB - OBJECTIVE: To evaluate the impact of incident transformed migraine on health care resource utilization, medication use, and productivity loss. In addition, the study estimates the total direct and indirect costs associated with transformed migraine. BACKGROUND: Emerging evidence indicates that migraine may be a chronic progressive disorder characterized by escalating frequency of headache attacks, often termed transformed migraine. Little is known about the economic impact of transformed migraine. METHODS: AMPP is a 5-year, national, longitudinal survey study of headache in the US. The study utilized data from the 2006 follow-up survey based on an initial sample of 14,544 adults identified as having migraine in either the 2004 screening or 2005 baseline survey. A diagnosis of migraine was assigned based on criteria proposed by the International Classification of Headache Disorders, 2nd Edition. Participants completed self-administered, validated questionnaires on headache features, frequency, impairment, resource use, medication use, and productivity loss. Direct and indirect headache-related costs were estimated using unit cost assumptions from the PharMetrics Patient-Centric database, wholesale acquisition costs (Red Book), and wage data from the US Bureau of Labor Statistics. Those who developed transformed migraine were compared with those who did not develop transformed migraine in the 1-2 year interval between screening/baseline and follow-up. RESULTS: A total of 7796 (54%) identified migraine cases completed the 2006 follow-up survey. Of those cases, 359 (4.6%) developed transformed migraine. Participants who developed transformed migraine reported significantly more primary care visits, neurologist or headache specialist visits, pain clinic visits, and emergency room visits compared with participants whose migraine remained episodic. Hospital nights and urgent care visits did not reach statistical significance. Transformed migraine participants reported significantly more time missed at work or school because of headaches and more time where work or school productivity was reduced by >50% in the previous 3 months because of headaches. Average per-person annual total costs, including direct and indirect costs, were 4.4-fold greater for those who developed transformed migraine ($7750) compared with those who remained episodic ($1757). CONCLUSION: Transformed migraine exacts a significantly higher economic toll on patients and health care systems compared with other forms of migraine. Our findings support the need to prevent migraine progression and to provide appropriate management and treatment of transformed migraine. AD - IMS Consulting, Falls Church, VA 22046, USA. AN - 19245386 AU - Munakata, J. AU - Hazard, E. AU - Serrano, D. AU - Klingman, D. AU - Rupnow, M. F. AU - Tierce, J. AU - Reed, M. AU - Lipton, R. B. DA - Apr DO - 10.1111/j.1526-4610.2009.01369.x DP - NLM ET - 2009/02/28 IS - 4 KW - Adolescent Adult Aged Aged, 80 and over Americas/epidemiology Data Collection Female Headache/*economics/epidemiology/*prevention & control Health Care Costs Health Personnel/economics/statistics & numerical data Health Surveys Humans Longitudinal Studies Male Middle Aged Migraine Disorders/*economics/epidemiology/*prevention & control Pharmaceutical Services/economics Retrospective Studies Young Adult LA - eng N1 - 1526-4610 Munakata, Julie Hazard, Elisabeth Serrano, Daniel Klingman, David Rupnow, Marcia F T Tierce, Jonothan Reed, Michael Lipton, Richard B Journal Article Research Support, Non-U.S. Gov't United States Headache. 2009 Apr;49(4):498-508. doi: 10.1111/j.1526-4610.2009.01369.x. Epub 2009 Feb 25. PY - 2009 SN - 0017-8748 SP - 498-508 ST - Economic burden of transformed migraine: results from the American Migraine Prevalence and Prevention (AMPP) Study T2 - Headache TI - Economic burden of transformed migraine: results from the American Migraine Prevalence and Prevention (AMPP) Study VL - 49 ID - 3701 ER - TY - JOUR AB - This article gives an overview of migraine in children. It outlines the epidemiology of the condition and describes presentation with headache and other symptoms and linked conditions. It aims to raise awareness of the diagnosis of migraine and its impact on children and young people, their families and school life. The author also describes methods of diagnosis and management, and the importance of recognising and of avoiding medication overuse. AD - National Migraine Centre, London, England. AN - 31468879 AU - Munro, K. DA - Jan 8 DO - 10.7748/ncyp.2018.e1048 DP - NLM ET - 2019/08/31 IS - 1 KW - Adolescent Child Child, Preschool Female Humans Male Migraine Disorders/*diagnosis/psychology/*therapy Pediatrics/*methods abdominal pain child health headache medicines migraine pain LA - eng N1 - 2046-2344 Munro, Katy Journal Article England Nurs Child Young People. 2019 Jan 8;31(1):38-47. doi: 10.7748/ncyp.2018.e1048. PY - 2019 SN - 2046-2336 SP - 38-47 ST - Diagnosing and managing migraine in children and young people T2 - Nurs Child Young People TI - Diagnosing and managing migraine in children and young people VL - 31 ID - 2977 ER - TY - JOUR AB - In this article, we describe the history and current state of psychosomatic medicine (PSM) in Japan and propose measures that could be considered based on our view of the future prospects of PSM in Japan. The Japanese Society of PSM (JSPM) was established in 1959, and the first Department of Psychosomatic Internal Medicine in Japan was established at Kyushu University In 1963. PSM in Japan has shown a prominent, unique development, with 3,300 members (as of March 2016), comprised of 71.6% of medical doctors including psychosomatic internal medicine (PIM) specialists, general internists, psychiatrists, pediatricians, obstetricians and gynecologists, dentists, dermatologists, and others. Most of the non-physician members include psychology and nursing staff specialists. The Japanese Society of Psychosomatic Internal Medicine (JSPIM), founded in 1996, is another major society with more than 1,200 physicians that is mainly composed of internists. The first joint congress of the five major PSM societies from each field was held in 2009. They included the Japanese Society of Psychosomatic Medicine, Psychosomatic Obstetrics and Gynecology, Psychosomatic Pediatric Medicine, Psychosomatic Dental Medicine, and Psychosomatic Internal Medicine. Several subdivided societies in related medical fields have also been established for cardiovascular, digestive, dermatological, and oriental medicine and for eating disorders, pain, fibromyalgia, stress science, behavioral medicine, and psycho-oncology. JSPM and JSPIM participate in international activities including publishing BioPsychoSocial Medicine (BPSM) and the establishment of a sister society relationship with the Germany College of PSM. PSM in Japan has adopted a variety of professional psychotherapies, including transactional analysis, autogenic therapy, and cognitive behavioral therapy. Mutual interrelationship has been promoted by the Japanese Union of Associations for Psycho-medical Therapy (UPM). Although PSM in Japan is functioning at a high level, there remain areas that could be improved. Among the 81 medical schools in Japan, just eight university hospitals have an independent department of PSM and of 29 dental schools only three dental university hospitals have a department of psychosomatic dentistry. Further accumulation of evidence regarding the mind-body relationship in clinical and basic science that is based on the latest advanced technology is necessary. The psychosomatic medicine community needs to make an even greater contribution to meeting the needs of modern society. The possibilities for the future development of PSM in Japan must be widely discussed. AD - Sanno Hospital, International College of Health and Welfare, 8-10-16 Akasaka Minato-Ku, Tokyo, 107-0052 Japan. Kansai Medical College, 2-3-1 Shinmachi, Hirakata, Osaka 573-1191 Japan. AN - 28105067 AU - Murakami, M. AU - Nakai, Y. C2 - PMC5240387 DO - 10.1186/s13030-017-0088-6 DP - NLM ET - 2017/01/21 KW - Asian college of psychosomatic medicine (ACPM) BioPsychoSocial medicine (BPSM) Holistic medicine International college of psychosomatic medicine (ICPM) Japanese society of psychosomatic internal medicine (JSPIM) Japanese society of psychosomatic medicine (JSPM) Primary care Psychosomatic medicine Yujiro Ikemi LA - eng N1 - 1751-0759 Murakami, Masato Nakai, Yoshihide Journal Article Review Biopsychosoc Med. 2017 Jan 16;11:1. doi: 10.1186/s13030-017-0088-6. eCollection 2017. PY - 2017 SN - 1751-0759 (Print) 1751-0759 SP - 1 ST - Current state and future prospects for psychosomatic medicine in Japan T2 - Biopsychosoc Med TI - Current state and future prospects for psychosomatic medicine in Japan VL - 11 ID - 4210 ER - TY - JOUR AB - Background Functional dyspepsia is common among adolescents. Pain reduces children's quality of life, psychosocial functioning, and school attendance. Amitriptyline is assumed to be one of the alternative treatments in functional dyspepsia. Objective To investigate the effectiveness of amytriptyline as a treatment for functional dyspepsia in adolescents. Methods We conducted a randomized, single-blind, controlled trial from January to March 2011 in junior and senior high school students in Dobo City, Aru Island District, Maluku Province. Adolescents suffering from functional dyspepsia and who fulfilled the inclusion criteria were eligible for the study. Subjects were randomized into two groups. Each group received 10 mg (for body weight < 35 kg) or 20 mg (for body weight >= 35 kg) amitriptyline or placebo once per day for 28 days. Pain frequency was measured in terms of abdominal pain episodes per month, and duration was measured in minutes. Data were analyzed using t-test. Results Eighty-eight students participated in this study: the amitriptyline group (43 subjects) and the placebo group (45 subjects). There were no statistically significant differences between the amitriptyline and placebo groups in frequency (P=0.777; 95% CI -0.846 to 1.129) or duration (P=0.728) of abdominal pain after treatment. Conclusion Amitriptyline is not more effective than placebo for treating functional dyspepsia in adolescents. AN - WOS:000391261300002 AU - Mustawa, I. AU - Supriatmo AU - Hakimi AU - Sinuhaji, A. B. DA - Sep DO - 10.14238/pi56.5.2016.262-6 IS - 5 N1 - Mustawa, Indra Supriatmo Hakimi Sinuhaji, Atan Baas 2338-476x PY - 2016 SN - 0030-9311 SP - 262-266 ST - Effectiveness of amitriptyline for treating functional dyspepsia in adolescents T2 - Paediatrica Indonesiana TI - Effectiveness of amitriptyline for treating functional dyspepsia in adolescents UR - ://WOS:000391261300002 VL - 56 ID - 2146 ER - TY - JOUR AD -, . AN - 26015177 AU - Mut DA - Apr 2 DO - 10.1007/s15006-015-2883-y DP - NLM ET - 2015/05/28 IS - 6 KW - Adolescent Bullying/*psychology Child Child Abuse/*psychology/statistics & numerical data Child Abuse, Sexual/*psychology/statistics & numerical data Chronic Pain/epidemiology/*psychology Cross-Sectional Studies Family Conflict/*psychology Female Humans Male Netherlands Risk Factors LA - ger N1 - Mut News Germany MMW Fortschr Med. 2015 Apr 2;157(6):10. doi: 10.1007/s15006-015-2883-y. OP - Mobbing und Missbrauch fördern chronischen Schmerz. PY - 2015 SN - 1438-3276 (Print) 1438-3276 SP - 10 ST - [Bullying and abuse induce chronic pain] T2 - MMW Fortschr Med TI - [Bullying and abuse induce chronic pain] VL - 157 ID - 3290 ER - TY - JOUR AB - Information about ways to support children with Juvenile Rheumatic Diseases (JRDs) in school will help maximize their involvement in this setting. For this study, children with JRDs provided their views about the support they need from school nurses, teachers, classmates, friends and leaders of after school activities. Parents provided information about their child's disease and about family functioning. Results indicated that positive family functioning was related to lower needs for support from school nurses, teachers, and classmates. Family functioning was not related to the support children needed from good friends. Receiving help during after school activities and school nurse availability were areas of concern for some children. Future studies should continue to assess needs for school support for adolescents, who may need more support at school due to a decreased reliance on family support. AN - WOS:000245295300001 AU - Nabors, L. A. AU - Iobst, E. A. AU - Weisman, J. AU - Precht, B. AU - Chiu, P. AU - Brunner, H. DA - Apr DO - 10.1007/s10882-007-9038-8 IS - 2 N1 - Nabors, Laura A. Iobst, Emily A. Weisman, Jason Precht, Barbara Chiu, Peter Brunner, Hermine Nabors, Laura/0000-0002-0884-8538 1573-3580 PY - 2007 SN - 1056-263X SP - 81-89 ST - School support and functioning for children with juvenile rheumatic diseases T2 - Journal of Developmental and Physical Disabilities TI - School support and functioning for children with juvenile rheumatic diseases UR - ://WOS:000245295300001 VL - 19 ID - 2695 ER - TY - JOUR AB - PURPOSE: The relationship between sleep bruxism (SB) and temporomandibular disorders (TMD) is unclear. This study aimed to estimate SB prevalence in an adolescent population and to investigate the relationship between SB frequency and prevalence of TMD signs/symptoms. MATERIALS AND METHODS: First-year students at a high school in Okayama, Japan, were recruited in 2005, with 195 subjects responding. The SB detection device was a miniature disposable device (BiteStrip, SLP) that indicated the total SB events per night on a 4-grade score. The subjects were divided into severe and nonsevere SB groups with SB frequency cutoffs. The subjects were examined for temporomandibular joint (TMJ) noise during mouth opening/closing, tenderness of the masticatory/cervical muscles, and range of TMJ condylar movement. The presence/absence of headache and shoulder stiffness was also determined by the interview. The odds ratio (OR) and confidence interval (CI) were calculated to test the relationship between SB frequency, gender difference, and presence of the TMD signs/symptoms by multiple regression analysis. RESULTS: Severe SB (more than 125 events per night) was significantly related to the presence of TMJ clicking (OR: 3.74, CI: 1.22-11.49, P = .02), while gender (male) was not related to the presence of TMJ clicking. Severe SB was not related to headache, though gender (male) was significantly related to headache (OR: 2.52, Cl: 1.04-6.11, P= .04) in these subjects. CONCLUSION: These results suggest that the presence of TMJ clicking was closely related to severe SB in an adolescent population. AD - Department of Oral and Maxillofacial Rehabilitation, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan. AN - 18717084 AU - Nagamatsu-Sakaguchi, C. AU - Minakuchi, H. AU - Clark, G. T. AU - Kuboki, T. DA - Jul-Aug DP - NLM ET - 2008/08/23 IS - 4 KW - Adolescent Analysis of Variance Female Headache/etiology Humans Logistic Models Male Masticatory Muscles/physiopathology Neck Muscles/physiopathology Risk Factors Sex Factors Sleep Bruxism/*complications/diagnosis Temporomandibular Joint Dysfunction Syndrome/*etiology LA - eng N1 - Nagamatsu-Sakaguchi, Chiyomi Minakuchi, Hajime Clark, Glenn T Kuboki, Takuo Journal Article Research Support, Non-U.S. Gov't United States Int J Prosthodont. 2008 Jul-Aug;21(4):292-8. PY - 2008 SN - 0893-2174 (Print) 0893-2174 SP - 292-8 ST - Relationship between the frequency of sleep bruxism and the prevalence of signs and symptoms of temporomandibular disorders in an adolescent population T2 - Int J Prosthodont TI - Relationship between the frequency of sleep bruxism and the prevalence of signs and symptoms of temporomandibular disorders in an adolescent population VL - 21 ID - 3707 ER - TY - JOUR AB - OBJECTIVES: This prospective study was carried out to assess lactate dehydrogenase (LDH) as a biochemical marker during acute painful episode and steady state in children with sickle cell disease (SCD). DESIGN AND METHODS: A prospective descriptive study has been carried out on children and adolescents with SCD and pain during a vaso-occlusive episode. A total of 76 patients aged 1-18 years were included. Assessment of pain was done using the suitable pain assessment tool (visual analogue scales, Oucher scale) for school and preschool children. Complete blood count, liver function tests, LDH and C-reactive protein assay were performed on all patients during acute painful episode and steady state. RESULTS: LDH has been found to increase significantly during acute painful episode compared with steady state (p < 0.01). There is also a significant positive correlation between LDH level and severity of pain (p < 0.05). In addition, C-reactive protein level was found to be significantly elevated during acute painful episode (p < 0.01) and its level correlates significantly with severity of pain (p = 0.01). CONCLUSION: From this study it can be concluded that LDH is a significant biochemical marker for the severity of pain during a vaso-occlusive episode in SCD. AD - Basrah Maternity and Children Hospital, College of Medicine, University of Basrah, Basrah, Iraq. AN - 21778705 AU - Najim, O. A. AU - Hassan, M. K. DO - 10.1159/000328416 DP - NLM ET - 2011/07/23 IS - 3 KW - Adolescent Anemia, Sickle Cell/complications/enzymology/genetics/*physiopathology C-Reactive Protein/metabolism Child Child, Preschool Female Humans Infant L-Lactate Dehydrogenase/*metabolism Liver Function Tests Male Pain/*etiology Prospective Studies *Severity of Illness Index Surveys and Questionnaires LA - eng N1 - 1421-9662 Najim, Oula Abdullah Hassan, Mea'ad Kadhum Journal Article Switzerland Acta Haematol. 2011;126(3):157-62. doi: 10.1159/000328416. Epub 2011 Jul 20. PY - 2011 SN - 0001-5792 SP - 157-62 ST - Lactate dehydrogenase and severity of pain in children with sickle cell disease T2 - Acta Haematol TI - Lactate dehydrogenase and severity of pain in children with sickle cell disease VL - 126 ID - 3888 ER - TY - JOUR AB - BACKGROUND: This cross-sectional study was conducted to obtain epidemiologic data on chronic musculoskeletal pain in the Japanese people, and with it a better understanding of the actual conditions and problems involved. METHODS: A questionnaire covering basic information, chronic musculoskeletal pain, daily life, quality of life, and social loss was prepared and mailed to 11507 individuals aged 18 years or older. Subjects were selected randomly nationwide in accordance with the demographic composition of Japan. RESULTS: The prevalence of chronic musculoskeletal pain was 15.4%. The prevalence was highest in people in their 30s to 50s. Pain occurred most frequently in the low back, neck, shoulder, and knee. Among symptomatic subjects, 42% sought treatment, by visiting a medical institution (19%), taking folk remedies (20%), or both (3%). Treatment was generally prolonged, with 70% of those treated reporting treatment durations of more than a year. Although 69% reported that their symptoms had improved, 30% reported unchanged or aggravated symptoms and dissatisfaction with treatment. Among symptomatic subjects, a high percentage of both men and women had lost jobs, left school, been absent from work or school, or had changed jobs. Basic activities of daily living (ADL) were disturbed in men, and the instrumental ADL (IADL) score was low in women. SF-36 scale scores were significantly lower in every area for subjects with chronic pain. CONCLUSIONS: Chronic musculoskeletal pain does not necessarily improve even with prolonged treatment. It adversely affects daily life and both physical and mental health. Because those suffering pain often increasingly need assistance in daily activities, people around them are also affected. The therapeutic system and treatment procedures for chronic musculoskeletal pain merit prompt review. AD - Department of Orthopaedic Surgery, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku, Tokyo, 160-8582, Japan. masa@sc.itc.keio.ac.jp AN - 21678085 AU - Nakamura, M. AU - Nishiwaki, Y. AU - Ushida, T. AU - Toyama, Y. C2 - PMC3140943 DA - Jul DO - 10.1007/s00776-011-0102-y DP - NLM ET - 2011/06/17 IS - 4 KW - Adolescent Adult Aged Aged, 80 and over Chronic Pain/*epidemiology Cross-Sectional Studies Female Humans Japan/epidemiology Male Middle Aged Musculoskeletal Pain/*epidemiology Prevalence Surveys and Questionnaires Young Adult LA - eng N1 - 1436-2023 Nakamura, Masaya Nishiwaki, Yuji Ushida, Takahiro Toyama, Yoshiaki Journal Article Research Support, Non-U.S. Gov't J Orthop Sci. 2011 Jul;16(4):424-32. doi: 10.1007/s00776-011-0102-y. Epub 2011 Jun 16. PY - 2011 SN - 0949-2658 (Print) 0949-2658 SP - 424-32 ST - Prevalence and characteristics of chronic musculoskeletal pain in Japan T2 - J Orthop Sci TI - Prevalence and characteristics of chronic musculoskeletal pain in Japan VL - 16 ID - 3635 ER - TY - JOUR AB - OBJECTIVE: To determine the extent, severity, and sex differences of psychosocial deficits in men and women with urologic chronic pelvic pain syndromes (UCPPS), which in the past have been considered separate bladder (interstitial cystitis-painful bladder syndrome) and prostate (chronic prostatitis-chronic pelvic pain syndrome) disorders. Evaluations of men and women separately suggest UCPPS is associated with increased anxiety and depression. However, studies directly testing deficits in broader psychosocial domains such as cognitive processes, intimate relationships, and trauma history, or tests of sex differences in the pattern of difficulties associated with UCPPS have not been performed. METHODS: A total of 233 female and 191 male UCPPS patients and 235 female and 182 male healthy controls (HCs) were recruited from 6 academic medical centers in the United States and evaluated with a comprehensive battery of symptom, psychosocial, and illness impact measures. Primary comparisons of interest were between UCPPS patients and HCs and between men and women with UCPPS. RESULTS: In addition to greater negative effect, male and female UCPPS patients show higher levels of current and lifetime stress, poorer illness coping, increased self-report of cognitive deficits, and more widespread pain symptoms compared with sex- and education-matched HCs. Similar problems were found in male and female UCPPS patients although female UCPPS patients showed increased self-report of childhood adversity and more widespread symptoms of pain and discomfort. CONCLUSION: Given the significance of psychosocial variables in prognosis and treatment of chronic pain conditions, the results add substantially to our understanding of the breath of difficulties associated with UCPPS and point to important areas for clinical assessment. AD - Department of Medicine, University of California, Los Angeles, Los Angeles, CA; Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA. Electronic address: naliboff@ucla.edu. Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. Department of Psychiatry, University of California San Diego, San Diego, CA. Division of Urologic Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO. Department of Urology, University of Washington, Seattle, WA. Department of Psychiatry, Washington University School of Medicine, St. Louis, MO. Department of Urology, University of Iowa, Iowa City, IA. Department of Psychiatry and Biobehavioral Sciences, University of Washington, Seattle, WA. Department of Anesthesiology, University of Michigan, Ann Arbor, MI; Department of Medicine, University of Michigan, Ann Arbor, MI. AN - 26099876 AU - Naliboff, B. D. AU - Stephens, A. J. AU - Afari, N. AU - Lai, H. AU - Krieger, J. N. AU - Hong, B. AU - Lutgendorf, S. AU - Strachan, E. AU - Williams, D. C2 - PMC4479402 C6 - NIHMS691545 DA - Jun DO - 10.1016/j.urology.2015.02.047 DP - NLM ET - 2015/06/24 IS - 6 KW - Adult Aged Aged, 80 and over Case-Control Studies Chronic Pain/*complications/*psychology Female Humans Male Middle Aged Pelvic Pain/*complications/*psychology Severity of Illness Index Urologic Diseases/*complications/psychology Young Adult LA - eng N1 - 1527-9995 Naliboff, Bruce D Stephens, Alisa J Afari, Niloo Lai, Henry Krieger, John N Hong, Barry Lutgendorf, Susan Strachan, Eric Williams, David MAPP Research Network U01 DK082345/DK/NIDDK NIH HHS/United States U01 DK082315/DK/NIDDK NIH HHS/United States DK82342/DK/NIDDK NIH HHS/United States DK82316/DK/NIDDK NIH HHS/United States U01 DK082316/DK/NIDDK NIH HHS/United States DK82370/DK/NIDDK NIH HHS/United States U01 DK082344/DK/NIDDK NIH HHS/United States U01 DK082333/DK/NIDDK NIH HHS/United States DK82315/DK/NIDDK NIH HHS/United States DK82344/DK/NIDDK NIH HHS/United States DK82325/DK/NIDDK NIH HHS/United States DK82333/DK/NIDDK NIH HHS/United States U01 DK082325/DK/NIDDK NIH HHS/United States U01 DK082370/DK/NIDDK NIH HHS/United States U01 DK082342/DK/NIDDK NIH HHS/United States DK82345/DK/NIDDK NIH HHS/United States Journal Article Research Support, N.I.H., Extramural Urology. 2015 Jun;85(6):1319-27. doi: 10.1016/j.urology.2015.02.047. PY - 2015 SN - 0090-4295 (Print) 0090-4295 SP - 1319-27 ST - Widespread Psychosocial Difficulties in Men and Women With Urologic Chronic Pelvic Pain Syndromes: Case-control Findings From the Multidisciplinary Approach to the Study of Chronic Pelvic Pain Research Network T2 - Urology TI - Widespread Psychosocial Difficulties in Men and Women With Urologic Chronic Pelvic Pain Syndromes: Case-control Findings From the Multidisciplinary Approach to the Study of Chronic Pelvic Pain Research Network VL - 85 ID - 3611 ER - TY - JOUR AB - BACKGROUND: Poor menstrual health and hygiene (MHH) is a globally recognised public health challenge. A pilot study of an MHH intervention was conducted in two secondary schools in Entebbe, Uganda, over 9 months. The intervention included five components delivered by the implementing partner (WoMena Uganda) and the research team: (i) training teachers to implement government guidelines for puberty education, (ii) a drama skit to reduce stigma about menstruation, (iii) training in use of a menstrual kit (including re-usable pads), (iv) guidance on pain relief methods including provision of analgesics and (v) improvements to school water, sanitation and hygiene (WASH) facilities. The aim of the process evaluation was to examine implementation, context and possible causal pathways. METHODS: We collected information on fidelity, dose, reach, acceptability, context and mechanisms of impact using (i) quantitative survey data collected from female and male students in year 2 of secondary school (ages 13-21; 450 at the baseline and 369 at endline); (ii) qualitative data from 40 in-depth interviews with parents, teachers and female students, and four focus group discussions with students, stratified by gender; (iii) data from unannounced visits checking on WASH facilities throughout the study; and (iv) routine data collected as part of the implementation. Quantitative data were used primarily to assess fidelity, dose and reach. Qualitative data were used primarily to assess acceptability, context and possible mechanisms. RESULTS: Both schools received all intervention elements that were delivered by the research team and implementing partner. The drama skit, menstrual kit and pain management intervention components were delivered with fidelity. Intervention components that relied on school ownership (puberty education training and WASH improvements) were not fully delivered. Overall, the intervention was acceptable to participants. Multilevel contextual factors including schools' social and physical environment, and family, cultural and social factors influenced the acceptability of the intervention in the school setting. The intervention components reinforced one another, as suggested in our theoretical framework. CONCLUSION: The intervention was feasible to deliver and acceptable to the schools and students. We propose a full-scale cluster-randomised trial to evaluate the intervention, adding a school-based MHH leadership group to address issues with school ownership. TRIAL REGISTRATION: ClinicalTrials.gov NCT04064736. Registered August 22, 2019, retrospectively registered. AD - 1Medical Research Council/Uganda Virus Research Institute & London School of Hygiene & Tropical Medicine Uganda Research Unit, Plot 51-59 Nakiwogo Road, Entebbe, Uganda. GRID: grid.415861.f. ISNI: 0000 0004 1790 6116 2London School of Hygiene & Tropical Medicine, Tavistock Place, London, WC1H 9SH UK. GRID: grid.8991.9. ISNI: 0000 0004 0425 469X WoMena Uganda, Plot 2150 Kaduyu Close, Ntinda-Kigowa, Kampala, Uganda. 4College of Humanities and Social Science, Makerere University, Kampala, Uganda. GRID: grid.11194.3c. ISNI: 0000 0004 0620 0548 Palm Tree Academy Uganda, Arua, Uganda. 6Uganda Virus Research Institute, Plot 51-59 Nakiwogo Road, Entebbe, Uganda. GRID: grid.415861.f. ISNI: 0000 0004 1790 6116 7MRC Tropical Epidemiology Group, London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT UK. GRID: grid.8991.9. ISNI: 0000 0004 0425 469X AN - 32346485 AU - Nalugya, R. AU - Tanton, C. AU - Hytti, L. AU - Kansiime, C. AU - Nakuya, K. AU - Namirembe, P. AU - Nakalema, S. AU - Neema, S. AU - Alezuyo, C. AU - Namuli Musoke, S. AU - Torondel, B. AU - Francis, S. C. AU - Ross, D. A. AU - Bonell, C. AU - Seeley, J. AU - Weiss, H. A. C2 - PMC7181508 DO - 10.1186/s40814-020-00585-2 DP - NLM ET - 2020/04/30 KW - Acceptability Dose Fidelity Menstrual health Process evaluation Reach School-based intervention LA - eng N1 - 2055-5784 Nalugya, Ruth Tanton, Clare Hytti, Laura Kansiime, Catherine Nakuya, Kevin Namirembe, Prossy Nakalema, Shamira Neema, Stella Alezuyo, Connie Namuli Musoke, Saidat Torondel, Belen Francis, Suzanna C Ross, David A Bonell, Chris Seeley, Janet Weiss, Helen A MR/P020283/1/MRC_/Medical Research Council/United Kingdom Journal Article Pilot Feasibility Stud. 2020 Apr 24;6:51. doi: 10.1186/s40814-020-00585-2. eCollection 2020. PY - 2020 SN - 2055-5784 (Print) 2055-5784 SP - 51 ST - Assessing the effectiveness of a comprehensive menstrual health intervention program in Ugandan schools (MENISCUS): process evaluation of a pilot intervention study T2 - Pilot Feasibility Stud TI - Assessing the effectiveness of a comprehensive menstrual health intervention program in Ugandan schools (MENISCUS): process evaluation of a pilot intervention study VL - 6 ID - 4204 ER - TY - JOUR AB - Objective: To evaluate the efficacy and safety of Drotaverine hydrochroride in children with recurrent abdominal pain. Design: Double blind, randomized placebo-controlled trial. Setting: Pediatric Gastroenterology clinic of a teaching hospital. Participants: 132 children (age 4-12y) with recurrent abdominal pain (Apley Criteria) randomized to receivedrotaverine (n=66) or placebo (n=66) orally. Intervention: Children between 4-6 years of age received 10 mL syrup orally (20 mg drotaverine hydrochloride or placebo) thrice daily for 4 weeks while children >6 years of age received one tablet orally (40 mg drotaverine hydrochloride or placebo) thrice daily for 4 weeks. Outcome Measures: Primary: Number of episodes of pain during 4 weeks of use of drug/placebo and number of pain-free days. Secondary: Number of school days missed during the study period, parental satisfaction (on a Likert scale), and occurrence of solicited adverse effects. Results: Reduction in number of episodes of abdominal pain [mean (SD) number of episodes 10.3 (14) vs 21.6 (32.4); P=0.01] and lesser school absence [mean (SD) number of school days missed 0.25 (0.85) vs 0.71 (1.59); P=0.05] was noticed in children receiving drotaverine in comparison to those who received placebo. The number of pain-free days, were comparable in two groups [17.4 (8.2) vs 15.6 (8.7); P=0.23]. Significant improvement in parental satisfaction score was noticed on Likert scale by estimation of mood, activity, alertness, comfort and fluid intake. Frequency of adverse events during follow-up period was comparable between children receiving drotaverine or placebo (46.9% vs 46.7%; P=0.98), Conclusion: Drotaverine hydrochloride is an effective and safe pharmaceutical agent in the management of recurrent abdominal pain in children. Keywords: AN - WOS:000363825600006 AU - Narang, M. AU - Shah, D. AU - Akhtar, H. DA - Oct IS - 10 N1 - Narang, Manish Shah, Dheeraj Akhtar, Hina Shah, Dheeraj/0000-0002-8489-4472 0974-7559 PY - 2015 SN - 0019-6061 SP - 847-851 ST - Efficacy and Safety of Drotaverine Hydrochloride in Children with Recurrent Abdominal Pain: A Randomized Placebo Controlled Trial T2 - Indian Pediatrics TI - Efficacy and Safety of Drotaverine Hydrochloride in Children with Recurrent Abdominal Pain: A Randomized Placebo Controlled Trial UR - ://WOS:000363825600006 VL - 52 ID - 2220 ER - TY - JOUR AB - The National Breakthrough Pain Study is a large observational study that assessed breakthrough pain (BTP) in a population of commercially insured community-dwelling patients with opioid-treated chronic pain. Eligible patients were identified from an administrative claims database, and consenting patients were asked to complete a structured telephone interview and several validated questionnaires. Questionnaires assessed pain interference with function (Brief Pain Inventory-Short Form), health status (Short Form 12 [SF-12] Health Survey), disability (Sheehan Disability Scale), work performance (World Health Organization Health and Work Performance Questionnaire), and mood (Generalized Anxiety Disorder-7 Screener [GAD-7] and Patient Health Questionnaire-2 [PHQ-2]). Of 2198 patients interviewed, 1278 patients had persistent pain controlled with opioid therapy; 1023 (80%) of these patients reported BTP. Patients had a median of 2.0 episodes of BTP per day (range, 1-50) and a median duration of BTP of 45 minutes (range, 1-720). Compared with patients without BTP, patients with BTP had more pain-related interference in function (Brief Pain Inventory, mean ± SD: 34.2 ± 15.6 vs 25.0 ± 15.7 [P < 0.001]), worse physical health (SF-12 physical component score: 29.9 ± 9.6 vs 35.1 ± 10.4 [P < 0.001]) and mental health (SF-12 mental component score: 47.4 ± 11.3 vs 49.3 ± 10.4 [P < 0.001]), more disability (Sheehan Disability Scale global impairment score: 15.1 ± 9.1 vs 10.6 ± 8.5; World Health Organization Health and Work Performance Questionnaire absolute absenteeism: 12.4 ± 59.9 vs 7.7 ± 44.9 hours [both P < 0.001]), and worse mood (GAD-7 score: 7.4 ± 5.9 vs 5.9 ± 5.4; PHQ-2 anhedonia score: 1.2 ± 1.1 vs 0.9 ± 1.0 [both P < 0.001]). In this population of community-dwelling patients with opioid-treated chronic pain, BTP was highly prevalent and associated with negative outcomes. This burden of illness suggests the need for specific treatment plans. AD - Teva Pharmaceuticals, Frazer, PA, USA Tufts University School of Medicine, Boston, MA, USA Analgesic Solutions, Natick, MA, USA EPI-Q, Inc, Oak Brook, IL, USA HealthCore, Inc, Wilmington, DE, USA Thayer County Health Services, Hebron, NE, USA MJHS Institute for Innovation in Palliative Care, New York, NY, USA. AN - 25599446 AU - Narayana, A. AU - Katz, N. AU - Shillington, A. C. AU - Stephenson, J. J. AU - Harshaw, Q. AU - Frye, C. B. AU - Portenoy, R. K. DA - Feb DO - 10.1097/01.j.pain.0000460305.41078.7d DP - NLM ET - 2015/01/20 IS - 2 KW - Adolescent Adult Aged Breakthrough Pain/*diagnosis/*epidemiology/therapy Cohort Studies Cross-Sectional Studies Female *Health Surveys/methods Humans Male Middle Aged Pain Measurement/*methods Prevalence Surveys and Questionnaires Treatment Outcome United States/epidemiology Young Adult LA - eng N1 - 1872-6623 Narayana, Arvind Katz, Nathaniel Shillington, Alicia C Stephenson, Judith J Harshaw, Qing Frye, Carla B Portenoy, Russell K Journal Article Observational Study Research Support, Non-U.S. Gov't United States Pain. 2015 Feb;156(2):252-259. doi: 10.1097/01.j.pain.0000460305.41078.7d. PY - 2015 SN - 0304-3959 SP - 252-259 ST - National Breakthrough Pain Study: prevalence, characteristics, and associations with health outcomes T2 - Pain TI - National Breakthrough Pain Study: prevalence, characteristics, and associations with health outcomes VL - 156 ID - 4109 ER - TY - JOUR AB - To investigate associations of bullying and abuse with pelvic floor symptoms, urogenital pain, and sexual health characteristics of women presenting to a multidisciplinary women's urology center. Retrospective review of a prospective database. Patients completed questions about bullying, abuse, sexual health and validated questionnaires including the Pelvic Floor Dysfunction Inventory (PFDI-20), Overactive Bladder Questionnaire (OAB-q), and visual analog scale (VAS 0-10) for genitourinary pain. Statistical analyses included Chi-squared and t tests, which compared victims of bullying and/or abuse to non-victims. Three hundred and eighty patients were reviewed. Three hundred and thirty-eight had data on bullying and abuse history. Out of 380, 94 (24.7 %) reported that they were victims of bullying. Out of 380, 104 (27.4 %) reported that they were victims of abuse. Women with a history of bullying and abuse had increased overall pain scores compared to those without a history of either. Women with a history of abuse and bullying had increased PFDI-20, POPDI, and UDI-6 scores compared to women who were not bullied or abused. There was no difference in being sexually active or in sexual satisfaction between the groups. Patients with a history of abuse and bullying had the greatest percentage of dyspareunia (p = 0.009). Women with a history of bullying, abuse, or both predict increased pelvic floor distress, urological symptoms, increased urogenital pain, and increased dyspareunia. Clinicians should screen for exposure to bullying or abuse in order to provide comprehensive resources to address these psychosocial issues. AN - WOS:000385180000007 AU - Nault, T. AU - Gupta, P. AU - Ehlert, M. AU - Dove-Medows, E. AU - Seltzer, M. AU - Carrico, D. J. AU - Gilleran, J. AU - Bartley, J. AU - Peters, K. M. AU - Sirls, L. DA - Nov DO - 10.1007/s11255-016-1383-z IS - 11 N1 - Nault, Tori Gupta, Priyanka Ehlert, Michael Dove-Medows, Emily Seltzer, Marlene Carrico, Donna J. Gilleran, Jason Bartley, Jamie Peters, Kenneth M. Sirls, Larry Dove-Medows, Emily/0000-0003-0272-8858 1573-2584 PY - 2016 SN - 0301-1623 SP - 1783-1788 ST - Does a history of bullying and abuse predict lower urinary tract symptoms, chronic pain, and sexual dysfunction? T2 - International Urology and Nephrology TI - Does a history of bullying and abuse predict lower urinary tract symptoms, chronic pain, and sexual dysfunction? UR - ://WOS:000385180000007 VL - 48 ID - 2138 ER - TY - JOUR AB - BACKGROUND: Craniomandibular disorders (CMD) and atypical facial pain (AFP) represent a clinical challenge. Whereas CMD patients respond to somatic approaches, somatization should be strictly avoided in AFP. The aim of this study was to establish prognostic criteria to identify an aggravated risk of a chronic course in CMD and AFP. METHOD: A total of 124 consecutive patients with CMD ( n=108) or AFP ( n=16) were examined by two interdisciplinary academic pain centers. Psychometric evaluation was conducted with standardized questionnaires (SCL-90R, STAXI, modified SBAS-IV). All patients were clinically assessed by a maxillofacial surgeon or specialized dentist. RESULTS: The following variables proved to be significant: age (risk for AFP vs CMD increased by 6% p.a.), decreased dysfunction index (13% higher risk for AFP vs CMD), and low scores concerning outwardly directed anger (12% higher risk for AFP vs CMD). There was no correlation between initial pain intensity and somatic parameters of disease as assessed by the standardized clinical examination. Low educational status proved to be the best predictor ( p<0.001) for patients presenting high initial pain with a marked discrepancy between somatic findings and subjective status. CONCLUSIONS: CMD patients differ from AFP patients regarding age, psychosocial isolation, outwardly directed anger, and a decreased dysfunction index. Additionally, initial pain intensity in patients presenting indistinct CMD/AFP can be considered as a valid predictor for a chronic course in pain. AD - Klinik und Poliklinik für Mund-Kiefer-Gesichtschirurgie, Klinikum rechts der Isar, Technische Universität München, Munich. A.Neff@lrz.tu-muenchen.de AN - 12961073 AU - Neff, A. AU - Wolowski, A. AU - Scheutzel, P. AU - Kolk, A. AU - Ladwig, K. H. AU - Grübl, A. AU - Marten-Mittag, B. AU - Hammes, M. AU - Horch, H. H. AU - Gündel, H. DA - Jul DO - 10.1007/s10006-003-0481-0 DP - NLM ET - 2003/09/10 IS - 4 KW - Adolescent Adult Aged Chronic Disease Diagnosis, Differential Facial Neuralgia/diagnosis/*etiology/psychology Female Humans Male Middle Aged Patient Care Team Personality Inventory Risk Factors Sick Role Somatoform Disorders/diagnosis/psychology Temporomandibular Joint Dysfunction Syndrome/diagnosis/*etiology/psychology LA - ger N1 - Neff, A Wolowski, A Scheutzel, P Kolk, A Ladwig, K H Grübl, A Marten-Mittag, B Hammes, M Horch, H-H Gündel, H English Abstract Journal Article Germany Mund Kiefer Gesichtschir. 2003 Jul;7(4):227-34. doi: 10.1007/s10006-003-0481-0. Epub 2003 Jun 26. OP - Differenzielle und gemeinsame Merkmale bei Patienten mit atypischem Gesichtsschmerz und kraniomandibularer Dysfunktion. PY - 2003 SN - 1432-9417 (Print) 1432-9417 SP - 227-34 ST - [Differential and common characteristics of patients with atypical facial pain and craniomandibular dysfunction] T2 - Mund Kiefer Gesichtschir TI - [Differential and common characteristics of patients with atypical facial pain and craniomandibular dysfunction] VL - 7 ID - 3556 ER - TY - JOUR AB - OBJECTIVE The aim of this study was to evaluate the incidence, presentation, and treatment outcomes of trigeminal nerve-mediated symptoms secondary to large vestibular schwannomas (VSs) with trigeminal nerve contact. Specifically, the symptomatic results of pain, paresthesias, and numbness after microsurgical resection or stereotactic radiosurgery (SRS) were examined. METHODS The authors conducted a retrospective review of a database for concomitant diagnosis of trigeminal neuralgia (TN) or trigeminal neuropathy and VS between 1994 and 2014 at a tertiary academic center. All patients with VS with TN or neuropathy were included, with the exception of those patients with neurofibromatosis Type 2 and patients who elected observation. Patient demographic data, symptom evolution, and treatment outcomes were collected. Population data were summarized, and outcome comparisons between microsurgery and SRS were analyzed at last follow-up. RESULTS Sixty (2.2%) of 2771 total patients who had large VSs and either TN or neuropathy symptoms met inclusion criteria. The average age of trigeminal symptom onset was 53.6 years (range 24-79 years), the average age at VS diagnosis was 54.4 years (range 25-79 years), and the average follow-up for the microsurgery and SRS groups was 30 and 59 months, respectively (range 3-132 months). Of these patients, 50 (83%) had facial numbness, 16 (27%) had TN pain, and 13 (22%) had paresthesias (i.e., burning or tingling). Subsequently, 50 (83%) patients underwent resection and 10 (17%) patients received SRS. Treatment of VS with SRS did not improve trigeminal symptoms in any patient. This included 2 subjects with unimproved facial numbness and 4 patients with worsened numbness. Similarly, SRS worsened TN pain and paresthesias in 5 patients and failed to improve pain in 2 additional patients. The Barrow Neurological Institute neuralgia and hypesthesia scale scores were significantly worse for patients undergoing SRS compared with microsurgery. Resection alleviated facial numbness in 22 (50%) patients, paresthesias in 5 (42%) patients, and TN in 7 (70%) patients. In several patients, surgery was not successful in relieving facial numbness, which failed to improve in 17 (39%) cases and became worse in 5 (11%) cases. Also, surgery did not change the intensity of facial paresthesias or neuralgia in 6 (50%) and 3 (25%) patients, respectively. Microsurgery exacerbated facial paresthesias in 1 (8%) patient but, notably, did not aggravate TN in any patient. CONCLUSIONS Overall, resection of large VSs provided improved outcomes for patients with concomitant TN, facial paresthesia, and numbness compared with SRS. However, caution should be used when counseling surgical candidates because a number of patients did not experience improvement. This was especially true in patients with preoperative facial numbness and paresthesias, who frequently reported that these symptoms were unchanged following surgery. AD - Departments of 1 Otorhinolaryngology and. Department of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota. Neurologic Surgery, School of Medicine, and. AN - 28084915 AU - Neff, B. A. AU - Carlson, M. L. AU - O'Byrne, M. M. AU - Van Gompel, J. J. AU - Driscoll, C. L. W. AU - Link, M. J. DA - Nov DO - 10.3171/2016.9.Jns16515 DP - NLM ET - 2017/01/14 IS - 5 KW - Child Child, Preschool Humans Magnetic Resonance Imaging Neuroma, Acoustic/*surgery *Radiosurgery Retrospective Studies Treatment Outcome Trigeminal Nerve Trigeminal Neuralgia/*surgery *BNI = Barrow Neurological Institute *CPA = cerebellopontine angle *GKS = Gamma Knife surgery *SRS = stereotactic radiosurgery *TN = trigeminal neuralgia *VS = vestibular schwannoma *acoustic neuroma *oncology *pain *surgery *trigeminal neuralgia *trigeminal neuropathy *vestibular schwannoma LA - eng N1 - 1933-0693 Neff, Brian A Carlson, Matthew L O'Byrne, Megan M Van Gompel, Jamie J Driscoll, Colin L W Link, Michael J Comment Journal Article United States J Neurosurg. 2017 Nov;127(5):992-999. doi: 10.3171/2016.9.JNS16515. Epub 2017 Jan 13. PY - 2017 SN - 0022-3085 SP - 992-999 ST - Trigeminal neuralgia and neuropathy in large sporadic vestibular schwannomas T2 - J Neurosurg TI - Trigeminal neuralgia and neuropathy in large sporadic vestibular schwannomas VL - 127 ID - 4065 ER - TY - JOUR AB - The majority of patients with migraine headaches are treated in non-specialized institutions though data on treatment outcomes are largely derived from tertiary care centers. The current non-interventional study explores efficacy and tolerability outcomes of patients with episodic migraines receiving topiramate as preventive agent in a general practice setting. A total of 366 patients (87% female, mean age 41.8 +/- 11.6 years) were eligible for migraine prevention and treated with flexible dose topiramate for 6 months (core phase), and optionally for a total of 12 months (follow-up phase). Overall, 261 patients (77.7% of safety analysis set, SAF) completed the core phase. Reasons for discontinuation included adverse events (2.1%), lost to follow-up (1.8%), other reasons (1.5%), and end of therapy (0.3%) though in the majority of patients who discontinued no reasons were listed. The median daily dose at endpoint was 50 mg/day (range, 25-187.5 mg/day). The median days with migraine headaches decreased from 6.0 to 1.2 days (p < 0.001), median pain intensity score decreased from 17.0 to 3.2 points (p < 0.001). In women with reported menstruation-associated migraine, the median number of migraine attacks decreased from 4.0 to 0.9 (p < 0.001). Absenteeism as well as triptan use decreased significantly, and significant improvements in activities of daily living and quality of life were reported. The most frequently reported AEs were paraesthesia (4.2%) and nausea (3%). Results suggest that migraine prevention with topiramate in a general practice is generally well tolerated and associated with a significant improvement in migraine headaches and related functional impairment. AD - Neurology Outpatient Clinic, St. Elisabeth Krankenhaus Köln, 50935 Cologne, Germany. gereon.nelles@uni-duisburg-essen.de AN - 19894100 AU - Nelles, G. AU - Schmitt, L. AU - Humbert, T. AU - Becker, V. AU - Sandow, P. AU - Bornhoevd, K. AU - Fritzsche, D. AU - Schäuble, B. C2 - PMC3452185 DA - Feb DO - 10.1007/s10194-009-0163-x DP - NLM ET - 2009/11/07 IS - 1 KW - Absenteeism Adolescent Adult Aged Analgesics, Opioid/therapeutic use Drug Administration Schedule Dysmenorrhea/drug therapy Electronic Health Records Family Practice Female Follow-Up Studies Fructose/*analogs & derivatives/therapeutic use Humans Male Middle Aged Migraine Disorders/classification/complications/*prevention & control Neuroprotective Agents/*therapeutic use Outcome Assessment, Health Care Pain Measurement/methods Prospective Studies Quality of Life Surveys and Questionnaires Time Factors Topiramate Young Adult LA - eng N1 - 1129-2377 Nelles, Gereon Schmitt, Lukas Humbert, Thomas Becker, Veit Sandow, Petra Bornhoevd, Karin Fritzsche, Dirk Schäuble, Barbara TOPMATMIG-0001 investigators Clinical Trial Journal Article Multicenter Study Research Support, Non-U.S. Gov't J Headache Pain. 2010 Feb;11(1):33-44. doi: 10.1007/s10194-009-0163-x. Epub 2009 Nov 6. PY - 2010 SN - 1129-2369 (Print) 1129-2369 SP - 33-44 ST - Prevention of episodic migraines with topiramate: results from a non-interventional study in a general practice setting T2 - J Headache Pain TI - Prevention of episodic migraines with topiramate: results from a non-interventional study in a general practice setting VL - 11 ID - 3472 ER - TY - JOUR AB - A sample of 7465 persons aged 10 to 17 years from the 1988 National Health Interview Survey on Child Health was used to assess the prevalence and impact of chronic conditions in adolescents. We defined a condition as chronic if it was first noted more than 3 months before the interview or a condition that ordinarily would be of lengthy duration, such as arthritis or heart disease. An estimated 31.5% of US adolescents were reported to have one or more chronic conditions. The most commonly reported chronic conditions included respiratory allergies, asthma, and frequent or severe headaches. Chronic conditions had widely varying impact on adolescent activity levels. On average, adolescents with chronic conditions experienced 3.4 bed days and 4.4 school absence days related to their chronic conditions in the year before the interview. Adolescents with chronic conditions were also reported to experience 35% more behavioral problems than their counterparts without chronic conditions. Adolescents with multiple chronic conditions had substantially more bed days, school absence days, and behaviroal problems than adolescents with a single chronic condition. Implications of these findings are discussed. AN - WOS:A1991GZ35000010 AU - Newacheck, P. W. AU - McManus, M. A. AU - Fox, H. B. DA - Dec DO - 10.1001/archpedi.1991.02160120035015 IS - 12 N1 - Newacheck, pw mcmanus, ma fox, hb PY - 1991 SN - 0002-922X SP - 1367-1373 ST - PREVALENCE AND IMPACT OF CHRONIC ILLNESS AMONG ADOLESCENTS T2 - American Journal of Diseases of Children TI - PREVALENCE AND IMPACT OF CHRONIC ILLNESS AMONG ADOLESCENTS UR - ://WOS:A1991GZ35000010 VL - 145 ID - 2960 ER - TY - JOUR AB - Background This is an update of the original Cochrane review, last published in 2009 (Huertas-Ceballos 2009). Recurrent abdominal pain (RAP), including children with irritable bowel syndrome, is a common problem affecting between 4% and 25% of school-aged children. For the majority of such children, no organic cause for their pain can be found on physical examination or investigation. Many dietary inventions have been suggested to improve the symptoms of RAP. These may involve either excluding ingredients from the diet or adding supplements such as fibre or probiotics. Objectives To examine the effectiveness of dietary interventions in improving pain in children of school age with RAP. Search methods We searched CENTRAL, Ovid MEDLINE, Embase, eight other databases, and two trials registers, together with reference checking, citation searching and contact with study authors, in June 2016. Selection criteria Randomised controlled trials (RCTs) comparing dietary interventions with placebo or no treatment in children aged five to 18 years with RAP or an abdominal pain-related, functional gastrointestinal disorder, as defined by the Rome III criteria (Rasquin 2006). Data collection and analysis We used standard methodological procedures expected by Cochrane. We grouped dietary interventions together by category for analysis. We contacted study authors to ask for missing information and clarification, when needed. We assessed the quality of the evidence for each outcome using the GRADE approach. Main results We included 19 RCTs, reported in 27 papers with a total of 1453 participants. Fifteen of these studies were not included in the previous review. All 19 RCTs had follow-up ranging from one to five months. Participants were aged between four and 18 years from eight different countries and were recruited largely from paediatric gastroenterology clinics. The mean age at recruitment ranged from 6.3 years to 13.1 years. Girls outnumbered boys in most trials. Fourteen trials recruited children with a diagnosis under the broad umbrella of RAP or functional gastrointestinal disorders; five trials specifically recruited only children with irritable bowel syndrome. The studies fell into four categories: trials of probiotic-based interventions (13 studies), trials of fibre-based interventions (four studies), trials of low FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides and polyols) diets (one study), and trials of fructoserestricted diets (one study). We found that children treated with probiotics reported a greater reduction in pain frequency at zero to three months postintervention than those given placebo (standardised mean difference (SMD) -0.55, 95% confidence interval (CI) -0.98 to -0.12; 6 trials; 523 children). There was also a decrease in pain intensity in the intervention group at the same time point (SMD -0.50, 95% CI -0.85 to -0.15; 7 studies; 575 children). However, we judged the evidence for these outcomes to be of low quality using GRADE due to an unclear risk of bias from incomplete outcome data and significant heterogeneity. We found that children treated with probiotics were more likely to experience improvement in pain at zero to three months postintervention than those given placebo (odds ratio (OR) 1.63, 95% CI 1.07 to 2.47; 7 studies; 722 children). The estimated number needed to treat for an additional beneficial outcome (NNTB) was eight, meaning that eight children would need to receive probiotics for one to experience improvement in pain in this timescale. We judged the evidence for this outcome to be of moderate quality due to significant heterogeneity. Children with a symptom profile defined as irritable bowel syndrome treated with probiotics were more likely to experience improvement in pain at zero to three months postintervention than those given placebo (OR 3.01, 95% CI 1.77 to 5.13; 4 studies; 344 children). Children treated with probiotics were more likely to experience improvement in pain at three to six months postintervention compared to those receiving placebo (OR 1.94, 95% CI 1.10 to 3.43; 2 studies; 224 children). We judged the evidence for these two outcomes to be of moderate quality due to small numbers of participants included in the studies. We found that children treated with fibre-based interventions were not more likely to experience an improvement in pain at zero to threemonths postintervention than children given placebo (OR 1.83, 95% CI 0.92 to 3.65; 2 studies; 136 children). There was also no reduction in pain intensity compared to placebo at the same time point (SMD -1.24, 95% CI -3.41 to 0.94; 2 studies; 135 children). We judged the evidence for these outcomes to be of low quality due to an unclear risk of bias, imprecision, and significant heterogeneity. We found only one study of low FODMAP diets and only one trial of fructose-restricted diets, meaning no pooled analyses were possible. We were unable to perform any meta-analyses for the secondary outcomes of school performance, social or psychological functioning, or quality of daily life, as not enough studies included these outcomes or used comparable measures to assess them. With the exception of one study, all studies reported monitoring children for adverse events; no major adverse events were reported. Authors' conclusions Overall, we found moderate-to low-quality evidence suggesting that probiotics may be effective in improving pain in children with RAP. Clinicians may therefore consider probiotic interventions as part of a holistic management strategy. However, further trials are needed to examine longer-term outcomes and to improve confidence in estimating the size of the effect, as well as to determine the optimal strain and dosage. Future research should also explore the effectiveness of probiotics in children with different symptomprofiles, such as those with irritable bowel syndrome. We found only a small number of trials of fibre-based interventions, with overall low-quality evidence for the outcomes. There was therefore no convincing evidence that fibre-based interventions improve pain in children with RAP. Further high-quality RCTs of fibre supplements involving larger numbers of participants are required. Future trials of low FODMAP diets and other dietary interventions are also required to facilitate evidence-based recommendations. AN - WOS:000400761200039 AU - Newlove-Delgado, T. V. AU - Martin, A. E. AU - Abbott, R. A. AU - Bethel, A. AU - Thompson-Coon, J. AU - Whear, R. AU - Logan, S. C7 - Cd010972 DO - 10.1002/14651858.CD010972.pub2 IS - 3 N1 - Newlove-Delgado, Tamsin V. Martin, Alice E. Abbott, Rebecca A. Bethel, Alison Thompson-Coon, Joanna Whear, Rebecca Logan, Stuart Coon, Jo Thompson/C-7923-2017 Coon, Jo Thompson/0000-0002-5161-0234; Logan, Stuart/0000-0002-9279-261X; Whear, Rebecca/0000-0002-8379-8198; Abbott, Rebecca/0000-0003-4165-4484 1361-6137 PY - 2017 SN - 1469-493X ST - Dietary interventions for recurrent abdominal pain in childhood T2 - Cochrane Database of Systematic Reviews TI - Dietary interventions for recurrent abdominal pain in childhood UR - ://WOS:000400761200039 ID - 2116 ER - TY - JOUR AB - Methods We retrospectively audited the health records of 18 patients with breathing pattern disorders (BPDs), who were diagnosed in our respiratory clinic (2015-2018), and then referred onto our dysfunctional breathing care pathway to a specialist speech and language therapist. Results The age of the patients ranged from 11 to 16 years (median: 14 years, 14 female/4 male patients). Comorbidities included the following: 16 patients had asthma, 2 patients had a tracheoesophageal fistula and esophageal atresia repair, one patient suffered from chronic regional pain syndrome, and one patient had chronic fatigue syndrome. The commonest BPD was induced laryngeal obstruction (ILO) in 16 patients (exercise-induced laryngeal obstruction [EILO] in 15). Other types of BPDs included hyperventilation syndrome in seven patients, psychogenic cough in eight, and dysphonia in one. A single BPD was present in 6 patients (mainly EILO), and two or more BPDs were present in 10 patients. Inducers of BPD symptoms were as follows: exercise in 16 patients, bullying in 3, anxiety in 14, emotions and stress in 11, weather in 3, posture in 1, and odors in 3. Significant school absenteeism was observed in most of the patients (2 weeks to 24 months). Significant delays in diagnosing BPD were noted (range: 1-24 months and median: 6 months). Emergency calls occurred in 14 patients, with one patient presenting with ILO and comorbidity of asthma needing intubation and ventilation. A 1-year follow-up of patients showed that there was a complete resolution of BPD in two patients, 14 had good control of BPD with confidence in ability to control their symptoms, showing improved morbidity, two had no improvement, and one lost to follow-up. Conclusion It is important to recognize and treat BPD early to limit the significant morbidity that adversely impacts the quality of life. AN - WOS:000535064600001 AU - Newson, T. P. AU - Elias, A. DA - Jul DO - 10.1002/ppul.24791 IS - 7 N1 - Newson, Timothy P. Elias, Annie 1099-0496 PY - 2020 SN - 8755-6863 SP - 1736-1744 ST - Breathing pattern disorders (dysfunctional breathing) characteristics and outcomes of children and young people attending a secondary care respiratory clinic T2 - Pediatric Pulmonology TI - Breathing pattern disorders (dysfunctional breathing) characteristics and outcomes of children and young people attending a secondary care respiratory clinic UR - ://WOS:000535064600001 VL - 55 ID - 1824 ER - TY - JOUR AB - OBJECTIVE: To compare the efficacy of pain control and opioid consumption between patients who receive opioid as primary analgesic therapy and those who receive ibuprofen. STUDY DESIGN: Prospective randomized trial. SETTING: Tertiary care academic hospital. SUBJECT AND METHODS: Adult patients undergoing outpatient otolaryngology surgery were assigned to take hydrocodone/acetaminophen or ibuprofen for postoperative analgesia. Patient-recorded pain scores and analgesic consumption were analyzed. RESULTS: Out of 185 recruits, 108 (58%) completed responses. Fifty-six patients (52%) received opioid medication for primary analgesic treatment versus 52 (48%) who received ibuprofen. There was no difference in reported pain scores between the treatment groups. Those who received ibuprofen as primary therapy reported a significantly lower consumption of opioid medication at 2.04 tablets/pills (95% CI, 0.9-3.1) versus 4.86 (3.6-6.1; P = .001). Based on multivariate analysis, male sex and older age exhibited lower reported pain scores, while older age and use of ibuprofen as primary therapy exhibited lower opioid requirements. CONCLUSION: For postoperative pain management in outpatient otolaryngology procedures, ibuprofen as primary therapy can provide equally effective pain control as compared with hydrocodone/acetaminophen while decreasing overall opioid requirement. Prescription pill counts are further described to help guide physician practices in the era of an opioid epidemic. AD - 1 Department of Otolaryngology-Head and Neck Surgery, Loma Linda University Health System, Loma Linda, California, USA. 2 Medical University of South Carolina, Charleston, South Carolina, USA. 3 School of Medicine, Loma Linda University, Loma Linda, California, USA. AN - 30832548 AU - Nguyen, K. K. AU - Liu, Y. F. AU - Chang, C. AU - Park, J. J. AU - Kim, C. H. AU - Hondorp, B. AU - Vuong, C. AU - Xu, H. AU - Crawley, B. K. AU - Simental, A. A. AU - Church, C. A. AU - Inman, J. C. DA - May DO - 10.1177/0194599819832528 DP - NLM ET - 2019/03/06 IS - 5 KW - Acetaminophen/*therapeutic use Adolescent Adult Aged Aged, 80 and over Ambulatory Surgical Procedures/*adverse effects Analgesics, Opioid/*therapeutic use Drug Combinations Female Humans Hydrocodone/*therapeutic use Ibuprofen/*therapeutic use Male Middle Aged Otorhinolaryngologic Surgical Procedures/*adverse effects Pain Measurement Pain, Postoperative/diagnosis/*drug therapy/etiology Prospective Studies Single-Blind Method Young Adult *endolaryngeal procedures *functional endoscopic sinus surgery *ibuprofen *opioid therapy *otologic surgery *outpatient surgery *parathyroidectomy *postoperative pain *septoplasty *thyroidectomy LA - eng N1 - 1097-6817 Nguyen, Khanh K Liu, Yuan F Chang, Crystal Park, Jaimie J Kim, Cherine H Hondorp, Brian Vuong, Christopher Xu, Helen Crawley, Brianna K Simental, Alfred A Church, Christopher A Inman, Jared C Comparative Study Journal Article Randomized Controlled Trial England Otolaryngol Head Neck Surg. 2019 May;160(5):839-846. doi: 10.1177/0194599819832528. Epub 2019 Mar 5. PY - 2019 SN - 0194-5998 SP - 839-846 ST - A Randomized Single-Blinded Trial of Ibuprofen- versus Opioid-Based Primary Analgesic Therapy in Outpatient Otolaryngology Surgery T2 - Otolaryngol Head Neck Surg TI - A Randomized Single-Blinded Trial of Ibuprofen- versus Opioid-Based Primary Analgesic Therapy in Outpatient Otolaryngology Surgery VL - 160 ID - 4171 ER - TY - JOUR AB - Previous studies have found a high number of childhood adversities in patients with chronic low back pain, particularly in patients reporting persisting problems after back surgery. Our aim was to reproduce these results. Within the framework of a comprehensive diagnostic assessment and psychometric evaluation, 109 inpatients who had been treated for low back pain were examined in the orthopedics department of a German university hospital. Five risk factors investigated by Schofferman and his staff (Schofferman et al., 1993) were re-assessed in all of our patients using a structured biographical interview. The German chronic low back pain group was also compared with an age- and gender-matched control group of 109 non-chronic pain patients with respect to these childhood adversities and additional ones. Only approximately 11% of the German chronic low back pain sample demonstrated three or more risk factors, compared with more than 50% in Schofferman's sample, and 47.7% showed none of the five risk factors, compared to only 11% in the Schofferman sample. Moreover, no significant differences in distribution either in terms of the individual risk factors or their cumulative frequency were found in the German chronic low back pain group compared with an age and gender-matched control group without chronic pain. Childhood adversities do not occur frequently in a non-selected group of patients with chronic low back pain. Earlier results showing an increased likelihood of the occurrence of psychosocial risk factors could not be confirmed. As a consequence, further psychic or psychosomatic diagnostics of patients with chronic low back pain are needed to define diagnostic subgroups. AD - Clinic and Polyclinic for Psychosomatic Medicine and Psychotherapy, Johannes Gutenberg-University, Mainz, Germany. ranickel@mail.uni-mainz.de AN - 12036309 AU - Nickel, R. AU - Egle, U. T. AU - Hardt, J. DO - 10.1053/eujp.2001.0336 DP - NLM ET - 2002/05/31 IS - 3 KW - Absenteeism Adolescent Adult Child Child Abuse/statistics & numerical data Child Abuse, Sexual/statistics & numerical data Child of Impaired Parents Child, Abandoned Child, Preschool Chronic Disease Female Follow-Up Studies Germany/epidemiology Humans Infant Low Back Pain/*epidemiology/etiology/psychology/surgery Male Middle Aged Orthopedic Procedures/statistics & numerical data Parent-Child Relations Risk Factors Socioeconomic Factors Substance-Related Disorders/epidemiology LA - eng N1 - Nickel, R Egle, U T Hardt, J Comparative Study Journal Article England Eur J Pain. 2002;6(3):221-8. doi: 10.1053/eujp.2001.0336. PY - 2002 SN - 1090-3801 (Print) 1090-3801 SP - 221-8 ST - Are childhood adversities relevant in patients with chronic low back pain? T2 - Eur J Pain TI - Are childhood adversities relevant in patients with chronic low back pain? VL - 6 ID - 3418 ER - TY - JOUR AB - Irritable bowel syndrome (IBS) belongs to functional gastrointestinal disorders and is characterized by abdominal pain and change in stool consistency and/or bowel habits. Etiological factors include gastrointestinal peristalsis disturbances, visceral hypersensitivity, chronic inflammation of the mucous membrane, dysbacteremia, intestinal infections, psychosomatic and nutritional factors. Gastrointestinal motility disturbances in case of IBS are manifested by the inhibition of the intestinal passage, which favors the development of constipation or occurrence of diarrhea. The aim of the study was to evaluate IBS symptoms and demonstrate the relationship between physical activity and place of residence amongst Warsaw University students. MATERIAL AND METHODS: The study was conducted in march, 2014 using a specific questionnaire, amongst Warsaw University students. The study group comprised 120 female patients, aged between 19 and 27 years (M=23.43; SD=1.29). The chi-square test was used for analysis, p<0.05 was considered as statistically significant. RESULTS: The BMI of investigated patients ranged between 16.30-31.22 kg/m2 (M=21.27; SD=2.71). The majority of respondents (76.6%) weighed within the normal limits. Abdominal pain or discomfort occurred more frequently in the group of students who considered their physical activity as low. In case of respondents with a low physical activity bowel movement disorders and stool continence changes occurred more often, as compared to those with moderate physical activity. The most common symptom was rectal tenesmus, the least common-presence of mucous in the stool. Analysis showed that students with low physical activity were more frequently absent from school/work, due to abdominal symptoms. The respondents with moderate activity more often considered their abdominal symptoms, being associated with stress. CONCLUSIONS: IBS symptoms are common amongst Warsaw University students. In case of respondents with low physical activity, abdominal pain or discomfort occurred more often. It has been demonstrated that diet and stress might contribute to the occurrence of abdominal symptoms, being evidence of IBS. AN - 26172165 AU - Niemyjska, S. AU - Ukleja, A. AU - Ławiński, M. DA - May DO - 10.1515/pjs-2015-0050 DP - NLM ET - 2015/07/15 IS - 5 KW - Abdominal Pain/epidemiology Adult Attitude to Health Comorbidity Constipation/epidemiology Diet/*statistics & numerical data *Exercise Female *Health Status Humans Irritable Bowel Syndrome/*epidemiology/psychology Poland Students/*statistics & numerical data Surveys and Questionnaires Young Adult LA - eng N1 - 2299-2847 Niemyjska, Sylwia Ukleja, Anna Ławiński, Michał Journal Article Poland Pol Przegl Chir. 2015 May;87(5):252-9. doi: 10.1515/pjs-2015-0050. PY - 2015 SN - 0032-373x SP - 252-9 ST - Evaluation Of Irritable Bowel Syndrome Symptoms Amongst Warsaw University Students T2 - Pol Przegl Chir TI - Evaluation Of Irritable Bowel Syndrome Symptoms Amongst Warsaw University Students VL - 87 ID - 3914 ER - TY - JOUR AB - Purpose of Review Headaches are not only responsible for restrictions in everyday life in adults. In children and adolescents, regular headaches lead also to reduced life quality and limitations in the social sphere, in school education, and in professional careers. Here, we provide an overview on the frequency of headache in children and adolescents with the aim of increasing awareness about this particular health issue. Recent Findings Overall, headache prevalence in children and adolescents has been increasing in recent years. From various regions worldwide, data describing headache, its forms, and consequences are growing. In addition, factors frequently correlated with headache are repeatedly investigated and named: besides genetic factors, psychosocial and behavioral factors are linked to the prevalence of headache. Increasing evidence indicates that headache is underestimated as a common disorder in children and adolescents. Accordingly, too little emphasis is placed by society on its prevention and treatment. Thus, the extent of the social and health economic burden of frequent headaches in children and adolescents needs to be better illustrated, worldwide. Furthermore, the data collected in this review should support the efforts to improve outpatient therapy paths for young headache patients. Factors correlating with headache in pupils can draw our attention to unmet needs of these patients and allow physicians to derive important therapy contents from this data. AN - WOS:000564933300001 AU - Nieswand, V. AU - Richter, M. AU - Gossrau, G. C7 - 62 DA - Aug DO - 10.1007/s11916-020-00892-6 IS - 10 N1 - Nieswand, Vera Richter, Matthias Gossrau, Gudrun Gossrau, Gudrun/0000-0002-0995-5482 1534-3081 PY - 2020 SN - 1531-3433 ST - Epidemiology of Headache in Children and Adolescents-Another Type of Pandemia T2 - Current Pain and Headache Reports TI - Epidemiology of Headache in Children and Adolescents-Another Type of Pandemia UR - ://WOS:000564933300001 VL - 24 ID - 1803 ER - TY - JOUR AB - Data from an interview and clinical examination in a study of 440 randomly selected school children were analyzed with regard to relationships between signs and symptoms of functional disturbances and diseases in the stomatognathic system. A correlation was found between reported clicking sounds from the temporomandibular joint (TMJ) and pain when opening the mouth wide. Children who had been treated orthodontically or who were undergoing such treatment did not differ from other children in the frequency of signs and symptoms. Correlations were found between recurrent headaches and tenderness in TMJ and TMJ muscles. Reported pain in the temple region was also correlated to tenderness in the TMJ and TMJ muscles. Further correlations were found between recurrent headaches and oral parafunctions such as lip-cheek-biting and nail-biting and also among nail-biting, tooth clenching, tooth-grinding, and frontal dental wear. Children who reported oral parafunctions had more frequent interferences in RP and tenderness in TMJ muscles. There were correlations between irregular movements of the lower jaw and interferences in RP as well as mediotrusion interferences. Finally, a strong correlation was found between tenderness of the TMJ (laterally and posteriorly) and tenderness of the TMJ muscles. AN - 6576609 AU - Nilner, M. DA - Jun DO - 10.3109/00016358309162319 DP - NLM ET - 1983/06/01 IS - 3 KW - Adolescent Bruxism/etiology Child Dental Occlusion, Traumatic/etiology *Habits Humans Malocclusion/etiology Mouth Diseases/*etiology Temporomandibular Joint Disorders/etiology Tooth Diseases/*etiology LA - eng N1 - Nilner, M Journal Article England Acta Odontol Scand. 1983 Jun;41(3):167-72. doi: 10.3109/00016358309162319. PY - 1983 SN - 0001-6357 (Print) 0001-6357 SP - 167-72 ST - Relationships between oral parafunctions and functional disturbances and diseases of the stomatognathic system among children aged 7-14 years T2 - Acta Odontol Scand TI - Relationships between oral parafunctions and functional disturbances and diseases of the stomatognathic system among children aged 7-14 years VL - 41 ID - 3928 ER - TY - JOUR AB - The first aim of this thesis was to investigate the prevalence of temporomandibular disorder (TMD) pain in adolescents an a Swedish county and whether there were differences in patient age and gender and in treatment given for TMD pain by dentists in Public Dental Service (PDS) clinics. The epidemiological variable TMD-S was introduced in the PDS in Ostergötland County, Sweden, in 2000 and is recorded for all adolescents aged 12-19 at the annual routine examination. Self-reported TMD pain in this investigation was based upon the response of the subjects to two questions: (1) Do you have pain in your temples, face, temporomandibular joint, or jaws once a week or more? and (2) Do you have pain when you open your mouth wide or chew, once a week or more? Dental records of 200 patients with TMD pain were randomly selected from the population to evaluate treatment given for TMD. Among 28,899 participating adolescents, 4.2% reported TMD pain. Prevalence increased with age, a significant difference was seen between boys and girls, and 34% of patients with TMD pain received TMD-relared treatment in dental clinics. The second aim was to evaluate the reliability and validity of self-reported TMD pain in 120 adolescents, 60 with self-reported TMD pain and 60 age- and sex-matched controls without TMD pain. All adolescents were examined twice at a PDS clinic. At the first examination, self-reported TMD pain was recorded for each patient. At the second examination, a clinical examination was made blind to the patients' self-report of pain symptoms, after which self-reported TMD pain was again recorded. The clinical examination was based upon the Research Diagnostic Criteria for TMD (RDC/TMD). Test-retest reliability of 0.83 (kappa) was found for the two questions. Sensitivity was 0.98 and specificity 0.90 for assessments made on the same day and 0.96 and 0.83, respectively, for assessments made 2-4 weeks apart. The third aim was to evaluate incidence, by age and gender, and temporal patterns of TMD pain in adolescents. This 3-year longitudinal study was carried out at all PDS clinics from 2000 to 2003. All individuals aged 12-19 years in the county who visited the clinics for annual examinations were eligible for the study. Overall, the annual incidence of TMD pain among 2255 participating adolescents was 2.9%. Incidence among girls (4.5% was significantly higher than in boys (1.3%). Incidence increased with age in girls and boys, although less so in boys. These adolescents were re-examined annually for 3 years, and a fluctuating pattern of TMD pain was common. The fourth and final aim was to investigate gender and age differences in pain behavior, jaw function, and psychosocial status in adolescents with self-reported TMD pain. A postal questionnaire was sent to 350 consecutive patients with self-reported TMD pain and 350 healthy age- and sex-matched individuals aged 12-19 years 2-4 weeks after their annual dental examination. The groups were divided into younger (age 12-15) and older (age 16-19) groups. The TMD and control groups differed significantly in most variables related to pain characteristics and psychosocial and behavioral factors. Multiple pain sites were significantly more common in the TMD than in the control group, but there were no gender differences. For adolescents reporting pain once a week or more, no gender differences were seen in pain intensities. Jaw function limitation, depression scores, and perceived need for TMD treatment were significantly higher overall in girls than in boys. Almost one-third of older girls, compared to one out of ten older boys, reported school absences and analgesic consumption because of their TMD pain. Older girls had significantly higher Graded Chronic Pain Scale scores than older boys. In conclusion, TMD pain increases with increasing age in adolescents and is more common in girls than in boys. A fluctuating pain pattern can be seen. TMD-S, with two self-report questions, has very good reliability and validity, and can be recommended for screening adolescents for TMD pain. TMD pain seems to have a greater Impact on girls than boys. particularly in ages 16-19 years. AD - Department of Stomatognathic Physiology, Faculty of Odontology, Malmö University, Sweden. AN - 17506471 AU - Nilsson, I. M. DP - NLM ET - 2007/05/18 IS - 183 KW - Adolescent Age Factors Child Facial Pain/epidemiology/psychology/therapy Female Humans Incidence Longitudinal Studies Male Pain Measurement Reproducibility of Results Self-Assessment Sex Factors Surveys and Questionnaires Sweden/epidemiology/ethnology *Temporomandibular Joint Disorders/epidemiology/psychology/therapy Temporomandibular Joint Dysfunction Syndrome/epidemiology/psychology/therapy LA - eng N1 - Nilsson, Ing-Marie Journal Article Research Support, Non-U.S. Gov't Sweden Swed Dent J Suppl. 2007;(183):7-86. PY - 2007 SN - 0348-6672 (Print) 0348-6672 SP - 7-86 ST - Reliability, validity, incidence and impact of temporormandibular pain disorders in adolescents T2 - Swed Dent J Suppl TI - Reliability, validity, incidence and impact of temporormandibular pain disorders in adolescents ID - 3245 ER - TY - JOUR AB - Patients with chronic pelvic pain are challenging, from both diagnostic and therapeutic viewpoints. At the pain clinic at the Medical College of Georgia School of Medicine, Augusta, we have discovered over the past 3 years that psychiatric disease is probably underrecognized in these patients and that physicians are often reluctant to discuss intimate details of a patient's sex life even though they may provide important information. In addition, sleep disorders are very prevalent. Use of vaginal-probe ultrasound may decrease the need for diagnostic laparoscopy, especially in patients without pelvic disease. In most cases, ovarian cysts in ovulating patients do not represent an abnormality. Laparoscopy and major pelvic surgery should be limited to patients with a high probability of anatomic abnormalities or persistent symptoms. AD - Department of Obstetrics and Gynecology, LSU School of Medicine, New Orleans 70112-2242. AN - 8247990 AU - Nolan, T. E. AU - Elkins, T. E. DA - Dec DP - NLM ET - 1993/12/01 IS - 8 KW - Adolescent Adult Chronic Disease Female Humans Pelvic Pain/diagnosis/*etiology/psychology/therapy LA - eng N1 - Nolan, T E Elkins, T E Journal Article Review England Postgrad Med. 1993 Dec;94(8):125-8, 131-4, 138. PY - 1993 SN - 0032-5481 (Print) 0032-5481 SP - 125-8, 131-4, 138 ST - Chronic pelvic pain. Differentiating anatomic from functional causes T2 - Postgrad Med TI - Chronic pelvic pain. Differentiating anatomic from functional causes VL - 94 ID - 3121 ER - TY - JOUR AB - Introduction: Sleep disorder in adolescents is a problem that is rarely considered by both parents and healthcare professionals. Ignorance of sleep disorders is likely caused by the very rare occurrence of associated sporadic or emergency cases. Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by abdominal pain and changes in the defecation pattern. Previous research has demonstrated IBS as one of the many causes of sleep disorders. Difficulty sleeping, frequent awakening, and difficulty returning to sleep after awakening are the symptoms often experienced by adolescents with IBS. The high incidence of IBS in adolescents and the large proportion of sleep disorders in IBS affect the quality of life and disrupt physical development, behaviour, and learning achievement. The relationship between IBS and sleep disorders in adolescents needs to be studied. This study aims to determine the relationship between sleep disorders and IBS in high school adolescents in Palembang. Methods: This is a cross-sectional study conducted on 294 high school adolescents in Palembang in June 2018. Random sampling method was used and the presence of IBS and sleep disturbances were assessed using a questionnaire. Results: Among all subjects, we found 113 subjects (38.4%) with IBS. Of these 113 subjects with IBS, only 60 subjects (53.1%) experienced sleep disorders. Conclusion: No correlation found between sleep disorders and IBS in adolescents. AN - WOS:000539387100001 AU - Noor, L. I. K. AU - Bakri, A. AU - Soejadhi, R. AU - Kesuma, Y. DO - 10.2147/ahmt.S248711 N1 - Noor, Laili Indah Kusumawati Bakri, Achirul Soejadhi, Rismarini Kesuma, Yudianita kesuma, yudianita/ABA-6282-2020 kesuma, yudianita/0000-0001-5074-9907 PY - 2020 SN - 1179-318X SP - 73-77 ST - Association Between Irritable Bowel Syndrome and Sleep Disturbance in Adolescents T2 - Adolescent Health Medicine and Therapeutics TI - Association Between Irritable Bowel Syndrome and Sleep Disturbance in Adolescents UR - ://WOS:000539387100001 VL - 11 ID - 1856 ER - TY - JOUR AB - OBJECTIVE: To evaluate the frequency, predisposing factors and symptomatology of headache among medical students. METHODS: The cross-sectional study was conducted from September to December 2013 and comprised students of two medical colleges of Karachi. International Classification of Headache Disorder-II criterion was used to diagnose and classify headache. SPSS 17 was used for statistical analysis. RESULTS: Of the 413 medical students studies, 326(79%) had tension type headache, and 87 (21%) had migraine. Headache was more frequent among females than males, with a ratio of 6.5:1. Both types of headache were significantly associated with self-reported disturbed sleep pattern, stress and various triggering factors (p<0.05 each). Both types greatly influenced individual's daily life with significant association with avoiding academics, extra-curricular activities, family and friends (p<0.05 each). High self-medication rate of 400(96.9%) was observed. CONCLUSIONS: The prevalence of headache among medical students was high with female predominance. Infrequent consultation needs to be addressed through awareness programmes. AD - Civil Hospital Karachi, Dow University of Health Sciences, Karachi. Medical Student, Sind Medical College, Jinnah Sindh Medical University, Karachi. AN - 26819160 AU - Noor, T. AU - Sajjad, A. AU - Asma, A. DA - Feb DP - NLM ET - 2016/01/29 IS - 2 KW - Adolescent Causality Cross-Sectional Studies Female Humans Male *Migraine Disorders/diagnosis/epidemiology/psychology/therapy Pakistan/epidemiology Prevalence Self Medication/statistics & numerical data Sex Factors *Stress, Psychological/epidemiology/physiopathology *Students, Medical/psychology/statistics & numerical data *Tension-Type Headache/diagnosis/epidemiology/psychology/therapy Young Adult Headache, Migraine, Medical students, Tension-type headache, Frequency. LA - eng N1 - Noor, Tooba Sajjad, Ali Asma, Anoosha Journal Article Pakistan J Pak Med Assoc. 2016 Feb;66(2):159-64. PY - 2016 SN - 0030-9982 (Print) 0030-9982 SP - 159-64 ST - Frequency, character and predisposing factor of headache among students of medical college of Karachi T2 - J Pak Med Assoc TI - Frequency, character and predisposing factor of headache among students of medical college of Karachi VL - 66 ID - 3639 ER - TY - JOUR AB - STUDY DESIGN: A randomized, controlled, single-center pilot study. OBJECTIVE: The aim of this study was to investigate the feasibility of running a trial to explore if early intervention in individuals with chronic low back pain (CLBP) would lead to an early return to work (RTW) and reduce sick leave during 12 months of follow-up compared with patients on a 3-month waiting list. SUMMARY OF BACKGROUND DATA: Back pain is the reason for numerous absent days from work. In Norway, the government initiated a priority program, Earlier Return to Work (ERTW), to reduce work absences through early intervention. However, no proper evaluation has been performed on populations with CLBP. There is no consensus on how RTW should be measured. Only a few studies have examined how waiting time affects RTW. METHODS: Fifty-eight patients were included in the study. The group with early intervention was examined within 2 weeks, and the group on the waiting list was examined after 12 weeks. The intervention was identical in both groups and consisted of an outpatient, intensive back school. The data were obtained by questionnaire after 3, 6, and 12 months. The primary outcome was absence from work. RESULTS: The sample size in a full-scale study must comprise at least 382 patients on the basis of the assumptions in the pilot. In the pilot study, early intervention directly compared with an ordinary waiting list did not significantly affect the number of sick leave days after 12 months of follow-up. CONCLUSION: A prerequisite for launching a full-scale clinical trial is a redesign of the intervention, an improvement of procedures concerning inclusion and randomization, and finally a more precise definition of RTW. LEVEL OF EVIDENCE: 3. AD - Department of Neurology, Molde Hospital, Møre and Romsdal Health Trust, Molde, Norway. Swedish National Institute of Public Health, Ostersund, Sweden. Unit for Applied Clinical Research, Norwegian University of Science and Technology, Trondheim, Norway. AN - 27802253 AU - Norbye, A. D. AU - Omdal, A. V. AU - Nygaard, M. E. AU - Romild, U. AU - Eldøen, G. AU - Midgard, R. C2 - PMC5113231 DA - Nov 1 DO - 10.1097/brs.0000000000001878 DP - NLM ET - 2016/11/02 IS - 21 KW - Adolescent Adult Aged Chronic Pain/*therapy Female Humans Low Back Pain/*therapy Male Middle Aged Norway Pain Measurement *Physical Therapy Modalities Pilot Projects *Return to Work Sick Leave Surveys and Questionnaires Time-to-Treatment Young Adult LA - eng N1 - 1528-1159 Norbye, Anja Davis Omdal, Aina Vedvik Nygaard, Marit Eikrem Romild, Ulla Eldøen, Guttorm Midgard, Rune Journal Article Randomized Controlled Trial Spine (Phila Pa 1976). 2016 Nov 1;41(21):E1257-E1264. doi: 10.1097/BRS.0000000000001878. PY - 2016 SN - 0362-2436 (Print) 0362-2436 SP - E1257-e1264 ST - Do Patients With Chronic Low Back Pain Benefit From Early Intervention Regarding Absence From Work?: A Randomized, Controlled, Single-Center Pilot Study T2 - Spine (Phila Pa 1976) TI - Do Patients With Chronic Low Back Pain Benefit From Early Intervention Regarding Absence From Work?: A Randomized, Controlled, Single-Center Pilot Study VL - 41 ID - 3530 ER - TY - JOUR AB - This chapter has reviewed the role of back school and educational programmes for the common and non-specific acute and subacute low back pain patient. The following seems to come out of this review. Education is an important part of patient care. However, several questions arise about the content of the education, the selection of patients, the patient compliance to instruction given, how the information is retained, and which outcome measures should be used. It is also important to realize that the back school is a modality or a tool that may be used as an adjunct, but as a sole treatment it seems to have less impact than in combination with other structured or goal-oriented programmes. When a back school is instituted in a hospital or in industry, it requires administrative and budgetary support and a multidisciplinary staff to successfully carry out the programme. The information given must be adapted to the needs of the participants and all members of the team must give the same information to the patient. A poorly structured back school where patients are dumped because the physician or other health care provider has nothing else to offer is a poor solution for the patient, a poor solution for the health care provider, and can only increase the patient's discomfort and health care costs. AN - 1477897 AU - Nordin, M. AU - Cedraschi, C. AU - Balagué, F. AU - Roux, E. B. DA - Oct DO - 10.1016/s0950-3579(05)80133-5 DP - NLM ET - 1992/10/01 IS - 3 KW - Adult Biomechanical Phenomena Child Health Behavior Health Knowledge, Attitudes, Practice Humans Learning Life Style Low Back Pain/*prevention & control/therapy Patient Education as Topic/*methods Primary Prevention *Program Development Stress, Psychological/therapy LA - eng N1 - Nordin, M Cedraschi, C Balagué, F Roux, E B U60/CCU206153-01/PHS HHS/United States Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Review England Baillieres Clin Rheumatol. 1992 Oct;6(3):685-703. doi: 10.1016/s0950-3579(05)80133-5. PY - 1992 SN - 0950-3579 (Print) 0950-3579 SP - 685-703 ST - Back schools in prevention of chronicity T2 - Baillieres Clin Rheumatol TI - Back schools in prevention of chronicity VL - 6 ID - 4068 ER - TY - JOUR AB - Purpose: To investigate the association between sleep duration, sleep initiation difficulties and psychological and somatic complaints. Methods: We used three cohorts of cross-sectional Swedish questionnaire data, from the Health Behaviours of School aged Children (1985/1986, 2005/2006, 2013/2014, n = > 18000, aged 11-15). Specific complaints (e.g. pain) and total complaint load were used as outcomes of sleep duration, sleep initiation difficulties and the combination of them both. Results: Sleeping less than recommended and sleep initiation difficulties were associated with increased odds of specific complaints and belonging to the group with the greatest complaint load. The combination of short sleep duration and sleep initiation difficulties were associated with higher odds than either sleep issue alone. No interaction effects between time and sleep variables were found regarding complaints. Conclusions: The findings support recent sleep duration recommendations. Further, sleep issues warrant a broad health assessment as they indicate a high likelihood of other complaints. AN - WOS:000447105200002 AU - Norell-Clarke, A. AU - Hagquist, C. DA - Oct DO - 10.1016/j.adolescence.2018.07.006 N1 - Norell-Clarke, Annika Hagquist, Curt Norell-Clarke, Annika/0000-0003-2008-0784 1095-9254 PY - 2018 SN - 0140-1971 SP - 12-21 ST - Child and adolescent sleep duration recommendations in relation to psychological and somatic complaints based on data between 1985 and 2013 from 11 to 15 year-olds T2 - Journal of Adolescence TI - Child and adolescent sleep duration recommendations in relation to psychological and somatic complaints based on data between 1985 and 2013 from 11 to 15 year-olds UR - ://WOS:000447105200002 VL - 68 ID - 1989 ER - TY - JOUR AB - Aim To explore the prevalence of school absenteeism for children with chronic pain and to identify the characteristics of children with chronic pain who report absenteeism. Methods Systematic review with meta-analyses of quantitative studies. Studies were included if they reported mean days absent from school in children with chronic pain aged 5-18 years, attending a full-time school program. Quality of evidence was assessed using the Mixed Methods Appraisal Tool. Participant characteristics of age, gender, pain duration, pain type, and data collection setting were collated. Results Eighteen quantitative studies involving 2963 children with chronic were included. Studies had moderate to high quality of evidence. Meta-analysis demonstrated 13.28 mean days were spent absent from school in a 60-day period (95% CI 10.21, 16.34) (p < 0.001). Participants were predominantly females (71.8%) aged 14.1 years (SD 2.32). The most experienced pain type was combined headache or head pain (46.9%) and average duration since pain onset was 32.5 months (SD 36.34). Conclusions Children with chronic pain aged 5-18 years are absent for approximately 22% of school days, in a 60-day period. Early, targeted intervention for absenteeism and poor school functioning is recommended. Future research could evaluate the role of school-based therapists in screening at risk students and improving attendance and outcomes. AN - WOS:000585398900001 AU - Norton, J. AU - Southon, N. DA - Nov DO - 10.1080/01942638.2020.1836705 IS - 3 N1 - Norton, Jen Southon, Nicole Southon, Nicole/0000-0001-9474-0752; Norton, Jennifer/0000-0001-7127-2060 1541-3144 PY - 2020 SN - 0194-2638 SP - 227-243 ST - Exploring the Prevalence of Pediatric Chronic Pain and School Absenteeism for Therapists Working in Schools: A Systematic Review with Meta-Analysis T2 - Physical & Occupational Therapy in Pediatrics TI - Exploring the Prevalence of Pediatric Chronic Pain and School Absenteeism for Therapists Working in Schools: A Systematic Review with Meta-Analysis UR - ://WOS:000585398900001 VL - 41 ID - 1787 ER - TY - CHAP A2 - Shapero, B. G. A2 - Mischoulon, D. A2 - Cusin, C. AB - Maria is a 54-year-old divorced caucasian female with a high school education and three adult children. She presented with primary symptoms of major depressive disorder (MDD) with comorbid symptoms of anxiety that persisted despite pharmacological treatment. She had a long-term, stable full-time job that required moderate physical activity. Maria experienced some periods of passive suicidal ideation (i.e., wishing to be dead), but no other suicidal ideation or behaviors were present. Psychiatric and Medical History Maria experienced domestic violence from 15 to 19 years of age, followed by the onset of MDD, post-traumatic stress disorder (PTSD), panic attacks, and agoraphobia. She had been on a variety of medications and in psychotherapy for the treatment of anxiety and depression, starting at the age of 20. At the age of 49, Maria started treatment with venlafaxine (Effexor (R)) of which she was taking 150 mg daily for the duration of her described yoga practice. Maria was successfully treated for breast cancer at age 49 with a lumpectomy and radiation. She had a history of chronic low back pain, treated without surgery, which had resolved prior to the initiation of yoga. Yoga Treatment Maria completed 12 weeks of 90-min of twiceweekly yoga practice. Before starting yoga, her Beck Depression Inventory-II (BDI-II) [1] total score was 38, indicative of severe depression. After 12 weeks of yoga her BDI-II had decreased to a 14, consistent with mild depression, a reduction of >50%, generally considered a "response" to treatment. Her State-Trait Anxiety Inventory (STAI-State Version) [2] score of 47 prior to beginning her yoga practice declined to a score of 23 after12 weeks of twice-weekly yoga practice, a reduction of >50%. STAI-State scores of greater than 39-40 have been suggested to be indicative of clinical levels of anxiety [3-5] - as such, Maria's scores changed from being in the clinical range to the nonclinical range after the yoga intervention. Maria demonstrated several factors to be considered in assessing the use of yoga-based therapy for the treatment of depression: (1) incomplete response or remission of symptoms of depression and anxiety when treated with an antidepressant, (2) comorbid anxiety disorders, and (3) past comorbid medical conditions. There is evidence that yoga-based therapies are useful for the treatment of unresolved depressive symptoms in the face of antidepressant therapy [6-8], comorbid anxiety disorders such as post-traumatic stress disorder (PTSD) [9], and comorbid medical disorders such as breast cancer [10, 11] and low back pain [12]. AN - WOS:000572010100020 AU - Nyer, M. AU - Roberg, R. AU - Nauphal, M. AU - Streeter, C. C. DO - 10.1007/978-3-319-97241-1_17 N1 - Nyer, Maren Roberg, Regina Nauphal, Maya Streeter, Chris C. 2626-241x PY - 2019 SN - 978-3-319-97241-1; 978-3-319-97240-4 SP - 223-231 ST - Yoga as a Treatment for Depression T2 - Massachusetts General Hospital Guide to Depression: New Treatment Insights and Options T3 - Current Clinical Psychiatry TI - Yoga as a Treatment for Depression UR - ://WOS:000572010100020 ID - 1959 ER - TY - JOUR AB - Introduction: Previous research has indicated that pain influences children's daily lives, resulting in absence from school, sleep problems, poor school performance and problems with social activities. Our study aims to characterise the nature, extent, impact and cost of chronic pain among Irish children. Methods and analysis: Using cluster-systematic random sampling, primary schools will be invited to participate and 6000 5-12-year-olds asked to complete questionnaires in school classrooms, at time points 1 year apart. Questionnaires will use internationally valid psychometric measures to assess a range of quality of life factors and chronic pain indicators among children, with corresponding parental/primary caregiver questions, which will be completed at home. Data will also be gathered on the cost of chronic pain. Space will be given for comments on how pain impacts on participants' lives and possible coping mechanisms. Ethics and dissemination: Ethical approval has been granted by the Research Ethics Committee, National University of Ireland, Galway. Dissemination of results will be via journal articles and conference presentations on the various aspects of the study (ie, prevalence, impact and economic cost of chronic pain among 5-12-yearolds living in Ireland). AN - WOS:000354648100041 AU - O'Higgins, S. AU - Doherty, E. AU - NicGabhainn, S. AU - Murphy, A. AU - Hogan, M. AU - O'Neill, C. AU - McGuire, B. E. C7 - e007426 DO - 10.1136/bmjopen-2014-007426 IS - 5 N1 - O'Higgins, Siobhan Doherty, Edel NicGabhainn, Saoirse Murphy, Andrew Hogan, Michael O'Neill, Ciaran McGuire, Brian E. o'higgins, siobhan e/P-3040-2014 Doherty, Edel/0000-0001-8756-8974; Murphy, Andrew/0000-0001-5549-8246 PY - 2015 SN - 2044-6055 ST - The prevalence, impact and cost of chronic non-cancer pain in Irish primary schoolchildren (PRIME-C): protocol for a longitudinal school-based survey T2 - Bmj Open TI - The prevalence, impact and cost of chronic non-cancer pain in Irish primary schoolchildren (PRIME-C): protocol for a longitudinal school-based survey UR - ://WOS:000354648100041 VL - 5 ID - 2259 ER - TY - JOUR AB - BACKGROUND: Prevalence of low back pain (LBP) rises rapidly during adolescence, reaching adult levels by the age of 18. It has been suggested that adolescent LBP is benign with minimal impact, despite limited evidence. METHODS: The aim of this study was to investigate the impact of LBP and the influence of chronicity, gender and presence of other spinal pain comorbidities at age 17. Subjects (n=1283) were categorised according to experiencing current and chronic LBP, gender and presence of other areas of spinal pain. LBP impact was ascertained via questions regarding seeking professional assistance, using medication, missing school/work, limited normal or recreational physical activity and health related quality of life (HRQOL). RESULTS: 12.3% of participants reported current but not chronic LBP, while 19.9% reported current chronic LBP. LBP was more commonly reported by females than males. Other spinal pain comorbidities were common in the LBP groups. Impact was greater in subjects with chronic LBP, in females and in those with other spinal pain comorbidities. CONCLUSION: LBP, and particularly chronic LBP, has a significant negative impact at 17 years. It is commonly associated with care seeking, medication use, school absenteeism, and reduced HRQOL. These findings support that adolescent LBP is an important public health issue that requires attention. AD - School of Physiotherapy and Curtin Health Innovation Research Institute, Curtin University, GPO Box U1987, Perth, WA 6845, Australia. AN - 22304903 AU - O'Sullivan, P. B. AU - Beales, D. J. AU - Smith, A. J. AU - Straker, L. M. C2 - PMC3313872 DA - Feb 5 DO - 10.1186/1471-2458-12-100 DP - NLM ET - 2012/02/07 KW - Adolescent Chronic Disease/epidemiology Comorbidity Cross-Sectional Studies Female Health Status Humans Low Back Pain/*epidemiology/physiopathology Male *Public Health Quality of Life Western Australia/epidemiology LA - eng N1 - 1471-2458 O'Sullivan, Peter B Beales, Darren J Smith, Anne J Straker, Leon M Journal Article Research Support, Non-U.S. Gov't BMC Public Health. 2012 Feb 5;12:100. doi: 10.1186/1471-2458-12-100. PY - 2012 SN - 1471-2458 SP - 100 ST - Low back pain in 17 year olds has substantial impact and represents an important public health disorder: a cross-sectional study T2 - BMC Public Health TI - Low back pain in 17 year olds has substantial impact and represents an important public health disorder: a cross-sectional study VL - 12 ID - 3302 ER - TY - JOUR AB - BACKGROUND: Few studies have documented early functional recovery after anterior cruciate ligament (ACL) reconstruction. PURPOSE: To quantify the time to early functional milestone achievement and change in function over 12 weeks after ACL reconstruction and to identify demographic characteristic predictors of the outcomes. STUDY DESIGN: Prospective, longitudinal, observational study. LEVEL OF EVIDENCE: Level 4. METHODS: A total of 182 patients (95 females, 87 males; mean ± SD age, 28 ± 12 years; mean ± SD body mass index [BMI], 25 ± 4 kg/m(2)) who received primary, unilateral, ACL reconstruction were included. Testing occurred before surgery as well as 1, 2, 4, 8, and 12 weeks postsurgery. Outcomes included demographic characteristics, self-reported functional milestone achievements and responses on the Short Musculoskeletal Function Assessment (SMFA) questionnaire. Time to functional milestone achievement was calculated, and patients were categorized into "faster" or "prolonged" recovery groups based on the median value. Longitudinal change in SMFA subscale scores (daily activities and mobility) as well as demographic predictors of functional recovery group assignment and postsurgical change in SMFA subscale scores were examined. RESULTS: Median time for discontinuing narcotic pain medication was 9 days, while that for discontinuing crutches was 15 days. Time to return to work occurred at a median of 11 days, return to school at 7 days, and return to driving at 11 days. Both SMFA subscale scores significantly decreased (improved) over time, with the greatest change occurring between 1 and 4 weeks postsurgery. The demographic predictor of faster functional recovery for discontinuation of narcotic pain medication was surgery with allograft; those for return to work were higher age, male sex, decreasing BMI, and sedentary/light occupational demand; and those for return to driving were higher age, male sex, and surgery on the left side of the body. CONCLUSION: Functional recovery occurs rapidly over the first month after ACL reconstruction for most patients. Nonmodifiable demographic characteristics may influence recovery time for specific functional milestones. CLINICAL RELEVANCE: Results can be used to counsel patients on early functional recovery after ACL reconstruction. AN - 29863963 AU - Obermeier, M. C. AU - Sikka, R. S. AU - Tompkins, M. AU - Nelson, B. J. AU - Hamilton, A. AU - Reams, M. AU - Chmielewski, T. L. C2 - PMC6044123 DA - Jul-Aug DO - 10.1177/1941738118779762 DP - NLM ET - 2018/06/05 IS - 4 KW - Adolescent Adult Anterior Cruciate Ligament Injuries/rehabilitation/*surgery *Anterior Cruciate Ligament Reconstruction/rehabilitation Automobile Driving Child Crutches Female Humans Longitudinal Studies Male Middle Aged Pain Management Prospective Studies *Recovery of Function Return to Work *Self Report Young Adult Acl outcomes rehabilitation return to driving return to work publication of this article. LA - eng N1 - 1941-0921 Obermeier, Michael C Sikka, Robby S Tompkins, Marc Nelson, Bradley J Hamilton, Abigail Reams, Megan Chmielewski, Terese L Journal Article Observational Study Sports Health. 2018 Jul-Aug;10(4):345-354. doi: 10.1177/1941738118779762. Epub 2018 Jun 4. PY - 2018 SN - 1941-7381 (Print) 1941-0921 SP - 345-354 ST - Examination of Early Functional Recovery After ACL Reconstruction: Functional Milestone Achievement and Self-Reported Function T2 - Sports Health TI - Examination of Early Functional Recovery After ACL Reconstruction: Functional Milestone Achievement and Self-Reported Function VL - 10 ID - 3669 ER - TY - JOUR AB - OBJECTIVES: Acute pain trajectories are associated with long-term outcomes such as persistent pain and functional disability in adults. However, there are limited data on acute postoperative pain trajectories in the pediatric population. The aims of this study were to investigate acute postoperative pain trajectories, their predictors, and their impact on long- term outcomes in adolescents with idiopathic scoliosis. METHODS: We evaluated the preoperative pain intensity, use of analgesics, psychosocial measures and physical functioning of adolescents scheduled to undergo spinal fusion, and their average 6-hour self-reported pain intensity scores for their entire hospital stay. Six months after surgery, baseline variables were reassessed. We used growth mixture modeling to conduct acute postoperative pain trajectory analysis and to identify predictors of pain trajectories. Generalized linear models were conducted to determine whether acute pain trajectories predict long-term outcomes. RESULTS: One hundred and six patients were included in the best-fitted acute pain trajectory model that included four classes that differed in initial pain intensity and rates of change over time. Preoperative pain catastrophizer status and use of analgesics significantly predicted pain trajectory membership. Furthermore, at the 6-month follow-up, patients experiencing moderate-to-severe pain in the acute postoperative period were more likely to report higher levels of pain severity, use pain medication, and miss a greater number of school/work days due to back pain in the last three months. Discussion. Preoperative assessment and analyzing the progression of pain in the acute postoperative period can help identify those at risk of negative long-term outcomes after surgery. AD - Department of Experimental Surgery, McGill University, Montreal, QC, Canada. Shriners Hospitals for Children-Canada, Montreal, QC, Canada. Faculty of Medicine, McGill University, Montreal, QC, Canada. Chronic Pain Services, Montreal Children's Hospital, Montreal, QC, Canada. Department of Anesthesia, McGill University, Montreal, QC, Canada. Department of Pediatric Orthopedics, McGill University, Montreal, QC, Canada. Department of Anesthesiology and Pain Medicine, Université de Montréal, Montreal, QC, Canada. Centre de Recherche Du Centre Hospitalier de L'Université de Montréal, Montreal, QC, Canada. Research Institute-McGill University Health Centre, Montreal, QC, Canada. AN - 32184913 AU - Ocay, D. D. AU - Li, M. M. J. AU - Ingelmo, P. AU - Ouellet, J. A. AU - Pagé, M. G. AU - Ferland, C. E. C2 - PMC7060857 DO - 10.1155/2020/9874739 DP - NLM ET - 2020/03/19 KW - Acute Pain/epidemiology/etiology Adolescent Back Pain/epidemiology/etiology Child Chronic Pain/epidemiology Female Humans Male Pain Measurement *Pain, Postoperative/epidemiology Scoliosis/*complications/*surgery Self Report Spinal Fusion/*adverse effects LA - eng N1 - 1918-1523 Ocay, Don Daniel Li, Mandy M J Ingelmo, Pablo Ouellet, Jean A Pagé, M Gabrielle Orcid: 0000-0002-7742-2717 Ferland, Catherine E Orcid: 0000-0002-5236-4215 Journal Article Research Support, Non-U.S. Gov't Pain Res Manag. 2020 Feb 24;2020:9874739. doi: 10.1155/2020/9874739. eCollection 2020. PY - 2020 SN - 1203-6765 (Print) 1203-6765 SP - 9874739 ST - Predicting Acute Postoperative Pain Trajectories and Long-Term Outcomes of Adolescents after Spinal Fusion Surgery T2 - Pain Res Manag TI - Predicting Acute Postoperative Pain Trajectories and Long-Term Outcomes of Adolescents after Spinal Fusion Surgery VL - 2020 ID - 3027 ER - TY - JOUR AB - BACKGROUND: Headaches are common among schoolchildren, who seem to be afflicted increasingly. AIM: To analyse children's descriptions of their headaches and their thoughts about them, it being assumed that children have insight into the conditions that affect their health. DESIGN OF STUDY: Interview study. SETTING: Two state schools in the city of Malmö, Sweden. METHOD: Fourteen children aged between ten and 12 years, who had gone to the school nurse more than once during the previous two-month period complaining of a headache, took part in thematically structured interviews. Qualitative analysis was performed, aimed at identifying the basic themes involved. RESULTS: The children were found to consistently associate their headaches with conditions in school, specifically with more theoretically-oriented subjects (maths or Swedish), a noisy and disorderly school environment, and insecure relations with classmates. The second theme they took up was insecurity or conflict within the family. Reports of this constituted a major part of the children's accounts of their life situation, despite their failing to link such matters with their headaches. Many of the children considered their patterns of reacting, such as feeling unable to cope or becoming angry, as contributing to their getting headaches. CONCLUSIONS: The children related their headaches consistently to everyday situations and to their relations with others. This highlights the need for broadening the consultation in terms of including personal and contextual factors. AU - Odegaard, Gunni AU - Lindbladh, Eva AU - Hovelius, Birgitta DA - 2003/03// DP - PubMed IS - 488 J2 - Br J Gen Pract KW - Adaptation, Psychological Child Family Health Female Headache Disorders Humans Male Noise Parent-Child Relations School Health Services School Nursing Stress, Psychological LA - eng PY - 2003 SN - 0960-1643 SP - 210-213 ST - Children who suffer from headaches--a narrative of insecurity in school and family T2 - The British Journal of General Practice: The Journal of the Royal College of General Practitioners TI - Children who suffer from headaches--a narrative of insecurity in school and family UR - http://www.ncbi.nlm.nih.gov/pubmed/14694697 VL - 53 ID - 132 ER - TY - JOUR AB - Anxiety disorders are common mental health problems amongst youth with harmful impacts often extending into adulthood. Mindfulness-based interventions (MBIs) have become increasingly popular for addressing mental health issues, particularly in schools; however, it remains unclear how effective they are for reducing youth anxiety. This meta-analysis aimed to evaluate the efficacy and effect moderators of MBIs on anxiety outcomes in children and adolescents. Eligible studies were published randomised controlled trials (RCTs) of MBIs conducted with participants aged 18 years or younger, investigating anxiety outcomes using a well-validated anxiety scale. A systematic search of RCTs published through to February 2019 identified 20 studies for inclusion (n = 1582). A random effects model was used to synthesise MBI effects. Stratified meta-analyses as well as individual, random effects meta-regressions were performed to examine how effects varied by age group, intervention setting, control type, research location, and intervention dosage. Although, across all studies, there was a small beneficial effect of MBIs on anxiety post treatment (d = 0.26), this was significantly moderated by research location, with RCTs conducted in Iran producing large effects (d = 1.25), and RCTs conducted in Western countries demonstrating no significant beneficial effect compared to controls (very small,d = 0.05). Effects were non-significant at follow-up assessment points. Post-treatment effects were significant for MBIs conducted with children (d = 0.41) and for MBIs when compared to passive controls (d = 0.33), but non-significant for adolescents (d = 0.21), for MBIs conducted in schools (d = 0.30) and in clinics (d = 0.13), and when MBIs were compared to active controls (d = 0.12). Results suggest that MBIs are likely to have a small to medium, yet temporary effect in reducing anxiety symptoms in children (not adolescents), but amongst Western youth populations the most likely outcome, from RCTs to date, is that MBIs produce no beneficial effect in anxiety reduction. Results revealed a lack of evidence to support investment in school-based MBIs to address youth anxiety. AN - WOS:000543193600001 AU - Odgers, K. AU - Dargue, N. AU - Creswell, C. AU - Jones, M. P. AU - Hudson, J. L. DA - Sep DO - 10.1007/s10567-020-00319-z IS - 3 N1 - Odgers, Katarzyna Dargue, Nicole Creswell, Cathy Jones, Michael P. Hudson, Jennifer L. Dargue, Nicole/ABE-5549-2020; Jones, Michael/A-9013-2013; Creswell, Cathy/L-9306-2013 Jones, Michael/0000-0003-0565-4938; Creswell, Cathy/0000-0003-1889-0956; Hudson, Jennie/0000-0001-5778-2670 1573-2827 PY - 2020 SN - 1096-4037 SP - 407-426 ST - The Limited Effect of Mindfulness-Based Interventions on Anxiety in Children and Adolescents: A Meta-Analysis T2 - Clinical Child and Family Psychology Review TI - The Limited Effect of Mindfulness-Based Interventions on Anxiety in Children and Adolescents: A Meta-Analysis UR - ://WOS:000543193600001 VL - 23 ID - 1812 ER - TY - JOUR AB - Headache is a recurrent somatic complaint in childhood and adolescence. In recent decades headache prevalence has increased while the age of onset has decreased. In most cases headache can be categorized as migraine or tension-type headache without significant organic pathology, i.e. head trauma, structural lesion, etc. Diagnosis according to the criteria of the International Headache Society is based on subjective reports by patients and their parents. The basic tools of clinical assessment are history, physical examination and a headache diary. Laboratory tests, including electroencephalography and imaging studies should not, as a rule, be undertaken routinely. Pathophysiological models with an impact on therapeutic interventions will be discussed. Childhood headache is often treated inappropriately in daily practice despite the availability of various options (including environmental, drug, and psychological therapy). Psychological therapy (relaxation training, biofeedback, stress management, etc.) as well as medication can be applied for prophylaxis. Minimal therapeutic interventions have been shown to be equally effective in a remarkable number of patients. Chronic Headache shows relevant comorbidity with anxiety and depression and is associated with somatization and school disorders. A careful investigation and an adequate therapy of eventual psychiatric comorbidity is therefore strongly recommended. AD - Abteilung für Kinder- und Jugendpsychiatrie der Psychiatrischen Klinik Ruprecht-Karls-Universität Heidelberg. rieke_oelkers@med.uni-heidelberg.de AN - 12474319 AU - Oelkers-Ax, R. AU - Resch, F. DA - Nov DO - 10.1024/1422-4917.30.4.281 DP - NLM ET - 2002/12/12 IS - 4 KW - Adolescent Adolescent Psychiatry Child Child Psychiatry Comorbidity Diagnosis, Differential Headache/etiology/*psychology/therapy Humans Migraine Disorders/etiology/*psychology/therapy *Patient Care Team Tension-Type Headache/etiology/psychology/therapy LA - ger N1 - Oelkers-Ax, R Resch, F English Abstract Journal Article Switzerland Z Kinder Jugendpsychiatr Psychother. 2002 Nov;30(4):281-93. doi: 10.1024/1422-4917.30.4.281. OP - Kopfschmerzen bei Kindern: Auch ein kinder- und jugendpsychiatrisches Problem? Pathogenese, Komorbidität, Therapie. PY - 2002 SN - 1422-4917 (Print) 1422-4917 SP - 281-93 ST - [Headache in children: also a problem for child and adolescent psychiatry? Pathogenesis, comorbidity, therapy] T2 - Z Kinder Jugendpsychiatr Psychother TI - [Headache in children: also a problem for child and adolescent psychiatry? Pathogenesis, comorbidity, therapy] VL - 30 ID - 3240 ER - TY - JOUR AB - Our objective was to translate the Functional Disability Inventory (FDI) into German, to evaluate its validity and to assess functional limitation in a large cohort of children and adolescents with juvenile fibromyalgia syndrome (jFMS). We administered several questions (e.g., sociodemographics, school-related issues) and questionnaires to 329 patients and one parent. The questionnaires included, among others, a German version of the FDI, the CHAQ (parent report), KIDSCREEN, tender point score (TPS), Depression Inventory for Children and Adolescents (DIKJ) and others. Patients were asked about the severity of pain today (NRS = numerical rating scale) and other symptoms. Internal consistency was evaluated with Cronbach's alpha. Construct validity of the FDI was evaluated by correlating the FDI with the questionnaires as well as with the pain and other variables, e.g., days missed school. An exploratory factor analysis (EFA) was also performed. Mean age was 13.9 years (SD +/- 2.48). Means were for pain today 5.37 (+/- 2.39) and for the TPS 39.71 (+/- 21.56). Internal consistency was alpha = .90. Low-to-moderate correlations were obtained between the FDI and the CHAQ (rho = .51**), KIDSCREEN (e.g., physical well-being rho = -.62**; peers and social support rho = -.28**) as well as the pain variables (NRS rho = .24**; TPS rho = .38**). Psychological variables were also correlated with the FDI (e.g., DIJK rho = .28**). An EFA suggested a two-factor solution. The FDI is a valid instrument for measuring functional limitations in German children and adolescents with jFMS. AN - WOS:000384228000013 AU - Offenbacher, M. AU - Kohls, N. AU - Walker, L. AU - Hermann, C. AU - Hugle, B. AU - Jager, N. AU - Richter, M. AU - Haas, J. P. DA - Oct DO - 10.1007/s00296-016-3504-5 IS - 10 N1 - Offenbaecher, Martin Kohls, Niko Walker, Lynn Hermann, Christiane Huegle, Boris Jaeger, Natalie Richter, Matthias Haas, Johannes-Peter Hugle, Boris/AAN-3064-2020 1437-160x PY - 2016 SN - 0172-8172 SP - 1439-1448 ST - Functional limitations in children and adolescents suffering from chronic pain: validation and psychometric properties of the German Functional Disability Inventory (FDI-G) T2 - Rheumatology International TI - Functional limitations in children and adolescents suffering from chronic pain: validation and psychometric properties of the German Functional Disability Inventory (FDI-G) UR - ://WOS:000384228000013 VL - 36 ID - 2142 ER - TY - JOUR AB - The irritable bowel syndrome (IBS) is characterized by alteration in bowel habits (i.e., constipation and/or diarrhea) and abdominal pain, and is most common gastrointestinal disorder in adults. The recurrent abdominal pain (RAP) in children is similar to IBS in adults except bowel habits, but there is no settled conception of IBS in children. In our department, diagnosis of pediatric IBS will be made if the child has; #1 functional gastrointestinal disorders without organic diseases, #2 abdominal pain and other gastrointestinal symptoms continuing more than 3 weeks, #3 psychogenic background factors. We experienced 63 cases of IBS (23.5% in all 268 cases) from April 1990 to March 1992 at our pediatric digestive outpatient clinic. They ranged from 4 to 15 years old and about 60% of them were elder than 13 years old. Psychogenic factors were usually related to environment of school life and home. Careful history taking and routine examination were most important for the diagnostic approach. Management of this disease included counseling and drug therapy. Almost all cases reached much better condition 1 to 6 weeks after the therapy started. The combination therapy with psychologist was required in a few cases. AD - Department of Pediatrics, Kitasato University School of Medicine. AN - 1287248 AU - Ohta, T. AU - Shindo, T. AU - Kojima, K. DA - Nov DP - NLM ET - 1992/11/01 IS - 11 KW - Adolescent Age Factors Child Child, Preschool Colonic Diseases, Functional/*diagnosis/etiology/therapy Counseling Female Humans Infant Male Parasympatholytics/therapeutic use Social Environment Stress, Psychological/complications LA - jpn N1 - Ohta, T Shindo, T Kojima, K English Abstract Journal Article Review Japan Nihon Rinsho. 1992 Nov;50(11):2724-8. PY - 1992 SN - 0047-1852 (Print) 0047-1852 SP - 2724-8 ST - [Irritable bowel syndrome in children] T2 - Nihon Rinsho TI - [Irritable bowel syndrome in children] VL - 50 ID - 3767 ER - TY - JOUR AB - This study aimed to obtain screening data on the maturity status of the tibial tuberosity in schoolchildren of higher elementary school grades for risk management of Osgood-Schlatter disease (OSD). The maturity stages and cartilage thicknesses at the tibial tuberosity were determined by ultrasonography on the occasion of a school-based musculoskeletal examination for 124 grade 5-6 elementary schoolchildren, and their associations with the students' demographic characteristics and OSD were examined. The time-dependent changes of the maturity status of the tibial tuberosity were also examined in grade 5 students (n = 26) by a longitudinal survey. The cross-sectional survey showed that the epiphyseal stage was reached in 89% of girls and 35% of boys. The girls who had experienced menarche (n = 28) were all in the epiphyseal stage and had a decreased cartilage thickness (p = 0.004, after adjusting maturity stages). Students with OSD (n = 5) were all girls in the epiphyseal stage, and only two of them had an increased cartilage thickness. During the longitudinal survey, a marked increase in cartilage thickness from the previous measurement was observed in three boys (without clinical symptoms) and a girl who newly developed OSD. Two students with OSD without chronic pain had thin cartilage. In conclusion, for schoolchildren of higher elementary school grades, the risk of OSD is higher among girls with the epiphyseal stage. Cartilage thickness may not contribute to the diagnosis of OSD, since thick cartilage is not very common in OSD. However, cartilage thickness may reflect the status of OSD. AN - WOS:000473750500072 AU - Ohtaka, M. AU - Hiramoto, I. AU - Minagawa, H. AU - Matsuzaki, M. AU - Kodama, H. C7 - 2138 DA - Jun DO - 10.3390/ijerph16122138 IS - 12 N1 - Ohtaka, Maiko Hiramoto, Izumi Minagawa, Hiroshi Matsuzaki, Masashi Kodama, Hideya Kodama, Hideya/0000-0002-7992-2408; Ohtaka, Maiko/0000-0002-7825-6546 1660-4601 PY - 2019 ST - Screening of the Maturity Status of the Tibial Tuberosity by Ultrasonography in Higher Elementary School Grade Schoolchildren T2 - International Journal of Environmental Research and Public Health TI - Screening of the Maturity Status of the Tibial Tuberosity by Ultrasonography in Higher Elementary School Grade Schoolchildren UR - ://WOS:000473750500072 VL - 16 ID - 1909 ER - TY - JOUR AB - BACKGROUND: Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder comprising abdominal pain, abdominal discomfort, and disordered defecation. The prevalence of IBS is 10-15% in the general population. This study investigated the prevalence of IBS and the relationship between IBS and stress, lifestyle, and dietary habits among nursing and medical school students. METHODS: A blank self-administrated questionnaire was used to survey 2,639 students studying nursing or medicine. This questionnaire asked about IBS symptoms, lifestyle, dietary intake, life events, anxiety, and depression. The questionnaires were collected from 2,365 students (89.6%) and the responses of 1,768 students (74.8%) were analyzed. RESULTS: The prevalence of IBS was 35.5% as a whole, 25.2% in males and 41.5% in females. Significantly higher stress scores (anxiety and depression) and life events were found in the IBS group than in the non-IBS group. Sleep disorders and the time spent sitting were also higher in males with IBS. In the IBS group, females ate less fish, fruit, milk, and green-yellow vegetables, and more processed food products than the non-IBS group (p = 0.001, p = 0.002, p = 0.032, p = 0.037, p < 0.001). The rates of missed meals and irregular mealtimes were significantly higher in females in the IBS group (p = 0.001, p = 0.013). CONCLUSIONS: The prevalence of IBS was higher among nursing and medical students, and further interventional studies are needed to improve IBS symptoms. AD - Department of Health and Nutrition, Nagoya Bunri University, Nagoya, Japan. AN - 21863219 AU - Okami, Y. AU - Kato, T. AU - Nin, G. AU - Harada, K. AU - Aoi, W. AU - Wada, S. AU - Higashi, A. AU - Okuyama, Y. AU - Takakuwa, S. AU - Ichikawa, H. AU - Kanazawa, M. AU - Fukudo, S. DA - Dec DO - 10.1007/s00535-011-0454-2 DP - NLM ET - 2011/08/25 IS - 12 KW - Adolescent Adult Feeding Behavior Female Humans Irritable Bowel Syndrome/*epidemiology *Life Style Male Prevalence Sex Factors Stress, Psychological/*epidemiology Students, Medical/statistics & numerical data Students, Nursing/statistics & numerical data Surveys and Questionnaires Young Adult LA - eng N1 - 1435-5922 Okami, Yukiko Kato, Takako Nin, Gyozen Harada, Kiyomi Aoi, Wataru Wada, Sayori Higashi, Akane Okuyama, Yusuke Takakuwa, Susumu Ichikawa, Hiroshi Kanazawa, Motoyori Fukudo, Shin Journal Article Japan J Gastroenterol. 2011 Dec;46(12):1403-10. doi: 10.1007/s00535-011-0454-2. Epub 2011 Aug 24. PY - 2011 SN - 0944-1174 SP - 1403-10 ST - Lifestyle and psychological factors related to irritable bowel syndrome in nursing and medical school students T2 - J Gastroenterol TI - Lifestyle and psychological factors related to irritable bowel syndrome in nursing and medical school students VL - 46 ID - 4002 ER - TY - JOUR AB - INTRODUCTION: Cephalalgia is one of the most common somatic complaints related to health problems in childhood and adolescence. OBJECTIVE: To measure the cephalalgia prevalence in adolescents from the city of São Paulo, Brazil, and associated factors. METHODS: This is a cross-sectional population-based study, carried out in 2015, with 539 adolescents of both sexes, aged between 15 and 19 years. The information was collected in a household survey, and the participants were selected from probabilistic sampling. Frequencies, χ2 test and logistic regression analysis were used in the study, and significance level was 5%. RESULTS: the estimated prevalence of cephalalgia was 38.2% (95%CI 33.8 - 42.7), and 7.8% (95%CI 5.6 - 10.7), migraine. The associated factors for cephalalgia were: female sex (OR = 2.2; 95%CI 1.4 - 3.4), Common Mental Disorder (OR = 2.8; 95%CI 1.7 - 4.9), vision impairment (OR = 2.6; 95%CI 1.6 - 4.2), besides back pain (OR = 2.2; 95%CI 1.3 - 3.5), sinusitis (OR = 2.0; 95%CI 1.2 - 3.4) and incomplete elementary education (OR = 3.0; 95%CI 1.6 - 5.6). CONCLUSION: The prevalence of headache among adolescents in the city of São Paulo represented more than 1/3 (one third) of this population. The main associated factors were sex, low schooling and the following comorbidities: common mental disorder and vision impairment. AD - Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, SP, Brazil. Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil. Hospital Alemão Oswaldo Cruz, São Paulo, SP, Brazil. AN - 32667464 AU - Okamura, M. N. AU - Goldbaum, M. AU - Madeira, W. AU - Cesar, C. L. G. DO - 10.1590/1980-549720200067 DP - NLM ET - 2020/07/16 KW - Adolescent Brazil/epidemiology Cross-Sectional Studies Female Headache/*epidemiology Health Surveys Humans Male Population Surveillance/*methods Prevalence Sex Distribution Socioeconomic Factors Urban Population/*statistics & numerical data LA - eng por N1 - 1980-5497 Okamura, Mirna Namie Goldbaum, Moisés Madeira, Wilma Cesar, Chester Luiz Galvão Journal Article Brazil Rev Bras Epidemiol. 2020;23:e200067. doi: 10.1590/1980-549720200067. Epub 2020 Jul 8. OP - Prevalência e fatores associados de cefaleia entre adolescentes: resultados de um estudo de base populacional. PY - 2020 SN - 1415-790x SP - e200067 ST - Prevalence of headache and associated factors among adolescents: results of a population-based study T2 - Rev Bras Epidemiol TI - Prevalence of headache and associated factors among adolescents: results of a population-based study VL - 23 ID - 4074 ER - TY - JOUR AB - The various entities generally called sickle cell disease (SCD) share two characteristics: sickle erythrocytes in the blood and clinical illness as a result of having these abnormal red cells. They include the homozygous HbSS condition sickle cell anemia, and the compound heterozygous states HbSC disease and HbS/thalassaemia, but not sickle cell trait (HbAS). Oral history passed down through generations in Africa relays accounts Of an inherited illness that manifests as recurrent episodes of sudden onset bone pain, and death during childhood [1]. In the medical literature, the earliest publication of the features of the disorder now called sickle cell disease was in 1874 by Africanus Horton [2]. Born of Igbo parents from Nigeria who lived in Sierra Leone, Horton graduated from the medical school of King's College London, and served as a colonel in the British army (Fig. 1). In his book The Diseases of Tropical Climates and Their Treatment, Horton [2] described the recurrent pain that is the hallmark of clinical manifestation of sickle cell disease, as well as the association of fever and cold weather. The characteristic hematological feature of sickle cell disease, "peculiar elongated and sickled red cells" was published in the 1910 issue of Archives of Internal Medicine by james Herrick, a Chicago cardiologist [3]. It was the first account of die pathology of SCD, and gave e condition the name it bears today. Since 1910, there have been remarkable advances in understanding the pathological basis of SCD. Three disease mechanisms stand out: haemolysis, vaso-occlusion, and impaired defense against infections. Premature destruction of red blood cells is mostly the end effect of erythrocyte sickling and membrane damage induced by crystallization and polymerization of deoxy-HbS [4]. However, in the uncommon condition of hyperhaemolysis syndrome, immunological mechanisms appear to play a dominant role in destruction of both die patient's own and transfused red blood cells [5]. Blood vessel occlusion in SCD is a process fairly simple in conception. However, the cellular and molecular details are complex. Various gaps in knowledge notwithstanding, the current model of vaso-occlusion in SCD views the process as the result of interactions between sickled and unsickled erythrocytes, leukocytes, platelets, plasma proteins, and the blood vessel wall [6,7]. The causes of impaired defense against infections in SCD include splenic hypofunction [8], a defect in the alternative pathway of complement [9,10], and possible reduction in the microbicidal capacity of white blood cells [11, 12]. Despite substantial developments in understanding die pathophysiology of SCD, application of this immense body of knowledge to medical treatment remains a major challenge. Interference with various disease mechanisms is the basis of many treatment modalities in SCD. This review will discuss new and developing therapies for SCD as a whole, and for specific manifestations of the hemoglobinopathy. AN - WOS:000233123700015 AU - Okpala, I. E. DA - Oct DO - 10.1016/j.hoc.2005.08.004 IS - 5 N1 - Okpala, IE 1558-1977 PY - 2005 SN - 0889-8588 SP - 975-+ ST - New therapies for sickle cell disease T2 - Hematology-Oncology Clinics of North America TI - New therapies for sickle cell disease UR - ://WOS:000233123700015 VL - 19 ID - 2754 ER - TY - JOUR AB - The significance of the musculoskeletal function of the neck-shoulder region in different headache types in children and adolescents is not clear. The purpose of this study was to investigate the association between different types of headache and the strength and mobility of the neck-shoulder region in 13-year-old schoolchildren. A structured questionnaire on headache was sent to all 1,409 children in the sixth grade in the city of Turku. Of the 1,135 (81%) children who completed the questionnaire, a sample from different headache groups was randomly selected for clinical examination. The study consisted of 59 children with migraine, 65 with episodic tension-type headache (TTHA), and 59 headache-free controls. Dynamic muscle strength of the upper extremities (UE endurance), mobility of both shoulders (UE mobility), and the cervical range of motion (CROM) were measured. Girls with episodic TTHA had lower UE endurance of both dominant and nondominant sides than girls in the other study groups. Girls with migraine had lower UE endurance of nondominant side than girls in the control group. In boys, no significant differences were observed. An interesting association between the function of the neck-shoulder region and headache complaints in adolescents was ascertained. AD - Department of Physical Medicine and Rehabilitation, Turku University Central Hospital, Turku, Finland. airi.oksanen@tyks.fi AN - 16920676 AU - Oksanen, A. AU - Metsähonkala, L. AU - Viander, S. AU - Jäppilä, E. AU - Aromaa, M. AU - Anttila, P. AU - Salminen, J. AU - Sillanpää, M. DA - Sep DO - 10.1080/09593980600822800 DP - NLM ET - 2006/08/22 IS - 4 KW - Adolescent Analysis of Variance Case-Control Studies Causality Cervical Vertebrae/*physiopathology Cross-Sectional Studies Female Finland Humans Male Migraine Disorders/*physiopathology Muscle Strength Range of Motion, Articular Sex Factors Shoulder Joint/*physiopathology Tension-Type Headache/*physiopathology Upper Extremity/*physiopathology LA - eng N1 - Oksanen, Airi Metsähonkala, Liisa Viander, Suvi Jäppilä, Eija Aromaa, Minna Anttila, Pirjo Salminen, Jouko Sillanpää, Matti Journal Article England Physiother Theory Pract. 2006 Sep;22(4):163-74. doi: 10.1080/09593980600822800. PY - 2006 SN - 0959-3985 (Print) 0959-3985 SP - 163-74 ST - Strength and mobility of the neck-shoulder region in adolescent headache T2 - Physiother Theory Pract TI - Strength and mobility of the neck-shoulder region in adolescent headache VL - 22 ID - 3627 ER - TY - JOUR AB - This study examined coping strategies of students living with sickle cell anemia. In-depth interviews were conducted on 10 students living with sickle cell anemia and eight were conducted on the health workers. To explain the sufferers view and experience, interpretative phenomenology approach was employed. Findings were that sufferers experience much pain and crisis. Their coping strategies include having plenty of rest and water, avoiding strenuous activities and taking their medications. They had a good knowledge of the disease but faced the challenges of combining caring for themselves and academic pursuit which create problems of adherence and finance for buying drugs and sponsoring their education at the same time. In conclusion, sufferers were coping well but there was still a need to address the problems of harsh university environment, finance and adherence. AD - Department of Sociology and Anthropology, Obafemi Awolowo University, Ile-Ife, Nigeria. omuoghal@yahoo.co.uk AN - 23865973 AU - Okumdi, M. C. AU - Victor, A. O. DO - 10.1080/00981389.2013.779358 DP - NLM ET - 2013/07/20 IS - 6 KW - Adaptation, Psychological Adult Anemia, Sickle Cell/*psychology Female *Health Knowledge, Attitudes, Practice Health Personnel/*psychology Humans Male Middle Aged Nigeria Students/*psychology *Universities Young Adult LA - eng N1 - 1541-034x Okumdi, Muoghalu Caroline Victor, Ajayi Oladele Case Reports Journal Article United States Soc Work Health Care. 2013;52(6):578-98. doi: 10.1080/00981389.2013.779358. PY - 2013 SN - 0098-1389 SP - 578-98 ST - Coping with sickle cell anemia in Nigerian universities: the case of Obafemi Awolowo University, Ile-Ife, Nigeria T2 - Soc Work Health Care TI - Coping with sickle cell anemia in Nigerian universities: the case of Obafemi Awolowo University, Ile-Ife, Nigeria VL - 52 ID - 3841 ER - TY - JOUR AB - This study investigated faecal calprotectin concentration, a measure of intestinal inflammation, in infants and children with abdominal pain. Faecal calprotectin was measured by an enzyme-linked immunosorbent assay kit in spot stool samples in 76 infants with typical infantile colic, 7 infants with transient lactose intolerance and 27 healthy infants. All infants were 2-10 wk of age. In addition, 19 children with recurrent abdominal pain (RAP; mean age 11.5 y), 17 with inflammatory bowel disease (IBD; mean age 11.1 y; 10 had Crohn's disease and 7 ulcerative colitis) and 24 healthy children (mean age 5.3 y) were studied. In infants with infantile colic the mean faecal calprotectin concentration was not different from that in healthy infants (278 +/- 105 vs 277 +/- 109 mg kg(-1), p = 0.97) or in infants with transient lactose intolerance (300.3 +/- 124 mg kg(-1), p = 0.60). The calprotectin level was similar in boys and girls and fell significantly with age (p = 0.04). Children with IBD had faecal calprotectin levels (293 +/- 218 mg kg(-1)) much higher than healthy children (40 +/- 28 mg kg(-1), p < 0.0001) and children with RAP without identified organic disease (18 +/- 24 mg kg(-1), p < 0.0001). CONCLUSION: Faecal calprotectin may differentiate between functional abdominal pain and IBD in school-aged children. In young infants high faecal calprotectin levels are normal. AD - Department of Paediatrics, University of Bergen, Norway. eola@haukeland.no AN - 11883817 AU - Olafsdottir, E. AU - Aksnes, L. AU - Fluge, G. AU - Berstad, A. DO - 10.1080/080352502753457932 DP - NLM ET - 2002/03/09 IS - 1 KW - Abdominal Pain/*diagnosis Adolescent Age Factors Biomarkers/analysis Case-Control Studies Child Child, Preschool Cohort Studies Diagnosis, Differential Diarrhea, Infantile/*diagnosis Feces/*chemistry Female Humans Infant Infant, Newborn Inflammatory Bowel Diseases/*diagnosis Leukocyte L1 Antigen Complex Male Membrane Glycoproteins/analysis/*metabolism Neural Cell Adhesion Molecules/analysis/*metabolism Probability Recurrence Sensitivity and Specificity Sex Factors LA - eng N1 - Olafsdottir, E Aksnes, L Fluge, G Berstad, A Comparative Study Journal Article Research Support, Non-U.S. Gov't Norway Acta Paediatr. 2002;91(1):45-50. doi: 10.1080/080352502753457932. PY - 2002 SN - 0803-5253 (Print) 0803-5253 SP - 45-50 ST - Faecal calprotectin levels in infants with infantile colic, healthy infants, children with inflammatory bowel disease, children with recurrent abdominal pain and healthy children T2 - Acta Paediatr TI - Faecal calprotectin levels in infants with infantile colic, healthy infants, children with inflammatory bowel disease, children with recurrent abdominal pain and healthy children VL - 91 ID - 3505 ER - TY - JOUR AB - The Chronic Pain Section at Reykjalundur has 33 beds for patients with various chronic pain problems. About 200 patients are treated annually. For 3 years, 158 patients were enrolled in a random study focusing on increasing the patients' functioning and eliminating analgesic drugs through an interdisciplinary rehabilitation program. Patients answered a questionnaire at admission, before discharge from the clinic and about one year after discharge. The follow-up was done with a mailed questionnaire. The focus was on the patients' functioning rather than absence of pain. The program's duration was 7 weeks. The first 2 weeks were utilized for evaluation, information and education (pain school). Pain relieving drugs were gradually withdrawn but anti-inflammatory drugs were used when indicated. Cognitive behavioral therapy was applied in an increasing number of cases over the 3 year period by specially trained nurses and a psychiatrist. Pain, anxiety and depression were self-evaluated on a numeric rating scale (NRS). About 50% of the patients had a history of pain for more than 5 years. Low back pain was the most common diagnosis (48.1%) and 28.5% had post-traumatic pain. A significant reduction in pain, anxiety and depression was found both at discharge (p < 0.0001) and at follow-up (p < 0.001). Before entering the program, only 18.4% of the patients were able to work whereas 48.1% returned to work after discharge and 59.2% were working at follow-up. AD - Chronic Pain Section, Reykjalundur Rehabilitation Center, 270 Mosfellsbaer, Iceland. magnuso@reykjalundur.is AN - 14757900 AU - Olason, M. DP - NLM ET - 2004/02/06 IS - 1 KW - Adolescent Adult Aged Chronic Disease Cognitive Behavioral Therapy Female Humans Iceland Male Middle Aged *Outcome Assessment, Health Care Pain/*rehabilitation *Patient Care Team Patient Satisfaction Rehabilitation Centers/organization & administration LA - eng N1 - Olason, Magnus Journal Article Netherlands Work. 2004;22(1):9-15. PY - 2004 SN - 1051-9815 (Print) 1051-9815 SP - 9-15 ST - Outcome of an interdisciplinary pain management program in a rehabilitation clinic T2 - Work TI - Outcome of an interdisciplinary pain management program in a rehabilitation clinic VL - 22 ID - 3267 ER - TY - BOOK A2 - Colombo, L. A2 - Bianchi, R. AB - Oral health problems affect children's quality of life by impairing their physical and psychological and social functioning wellbeing. The main oral health related problem in preschool children is associated with dental pain that may affect sleep, cause difficulty in eating and affect learning. Sleep impairment and difficulty in eating in children contributes to malnutrition. Knowledge of oral and social problems that trigger pain can be used to establish preventive and treatment priorities. There is new research on oral impacts in quality of life in preschool children. This chapter will explore how the mouth affects quality of life and the epidemiology of dental pain including the determinants of oral diseases. In addition, the chapter reviews strategies to promote oral health in preschool children. Among oral health problems that may affect preschool children are dental caries, dental trauma, dental erosion, malocclusion and oral soft tissues lesions. There is a universal decline in the prevalence and severity of dental caries in children. On the other hand, dental trauma, malocclusion and enamel erosion are increasing in preschool children. New data are available on the lifecourse approach to the development of caries and malocclusion. As stated earlier, preschool children may be affected by dental pain from dental caries and traumatized teeth. Recent reports highlight the clear association between dental caries and gingivitis and social economic status. Traditional dental prevention carried out by dentists and dental personnel using the High Risk Strategy that targets children considered to be more prone to caries, have been relatively ineffective [1]. We will report on systematic reviews of dental health education. The development of oral health promotion policies for preschool children is especially important due to the possibility of positively influencing the acquisition of healthy behaviors and standards that are sustainable along the life course. Health promotion strategies aimed at the child is a responsibility not only of individuals, but of families and communities. The main strategies to promote oral health for this group of children should be common risk factor approach (CRFA); integrating oral health promotion with general health promotion directed at diet, cleanliness and prevention of trauma. Public health approaches using the Whole Population Strategies, such as health promoting nurseries and schools, should have the highest priority. Chairside prevention directed at individuals should include improving include diet, particularly in relation to non-milk extrinsic sugars, improve oral hygiene, fluoride application, fissure sealants and mouth guards to prevent dental trauma. AN - WOS:000284337000003 AU - Oliveira, L. B. AU - Sheiham, A. AU - Bonecker, M. N1 - Oliveira, Luciana Butini Sheiham, Aubrey Boenecker, Marcelo PY - 2010 SN - 978-1-60876-026-8 SP - 39-58 ST - ORAL IMPACTS ON QUALITY OF LIFE IN PRESCHOOL CHILDREN T2 - Preschool Children: Physical Activity, Behavioral Assessment and Developmental Challenges TI - ORAL IMPACTS ON QUALITY OF LIFE IN PRESCHOOL CHILDREN UR - ://WOS:000284337000003 ID - 2579 ER - TY - JOUR AB - BackgroundChronic nonbacterial osteomyelitis (CNO) is an autoinflammatory bone disorder that if left untreated can result in bone destruction and severe continuing pain due to persistent inflammation. The impact this chronic disease has on the daily lives of affected children and their families is not well known. The purpose of this study is to understand the disease burden and socioeconomic and psychological impact of CNO from the patients' and families' perspectives and identify areas of improvement for patient care and reduced disease burden based on patients' and families' responses.MethodsParticipants were invited through a social media platform group and at clinic visits at Stanford Children's Health. An online survey was administered to patients with a diagnosis of CNO made at <22years of age and/or the parent/guardian of a patient with CNO diagnosis made at <22years of age.ResultsThere was a total of 284 survey participants. The median age at CNO diagnosis was 10years (range 2-22+). Median time from first CNO symptom to diagnosis was 2years. Antibiotics were used in 35% of patients prior to CNO diagnosis; of these, 24% received antibiotics for greater than 6months. Between 25 and 61% reported a negative effect of CNO on relationships, school/work performance, or finances; and 19-50% reported effects on psychosocial well-being. The majority agreed patients' performance with daily tasks and hobbies was challenged bypain, fatigue and physical limitation related to CNO.ConclusionsPatients with CNO experienced on average a 2-year delay in diagnosis and receiving effective treatments. At least 25% reported problems with relationships, school, work, finances and well-being due to CNO. Recognition of these challenges emphasizes the need to increase awareness of this disease and address the socioeconomic stressors and mental health issues in order to provide optimal care of children with CNO. AN - WOS:000453359900001 AU - Oliver, M. AU - Lee, T. C. AU - Halpern-Felsher, B. AU - Murray, E. AU - Schwartz, R. AU - Zhao, Y. D. AU - Workgrp, Carra Svard Crmo Cno C7 - 78 DA - Dec DO - 10.1186/s12969-018-0294-1 N1 - Oliver, Melissa Lee, Tzielan C. Halpern-Felsher, Bonnie Murray, Elizabeth Schwartz, Rebecca Zhao, Yongdong Oliver, Melissa/0000-0002-7689-2573 1546-0096 PY - 2018 ST - Disease burden and social impact of pediatric chronic nonbacterial osteomyelitis from the patient and family perspective T2 - Pediatric Rheumatology TI - Disease burden and social impact of pediatric chronic nonbacterial osteomyelitis from the patient and family perspective UR - ://WOS:000453359900001 VL - 16 ID - 1973 ER - TY - JOUR AB - Background: Youth with sickle cell disease (SOD) experience chronic symptoms that significantly interfere with physical, academic, and social-emotional functioning. Thus, to effectively manage SCD, youth and caregivers must work collaboratively to ensure optimal functioning. The goal of the current study was to examine the level of involvement in disease management tasks for youth with SCD and their caregivers. The study also examined the relationship between involvement in disease management tasks, daily functioning, and coping skills. The study utilized collaborative care and disease management theoretical frameworks. Methods: Youth and caregivers participated in the study during an annual research and education day event. Forty-seven patients with SCD aged 6 to 18 years and their caregivers completed questionnaires examining level of involvement in disease management tasks, youth functional disability, and youth coping strategies. Caregivers also completed a demographic and medical history form. Results: Parents and youth agreed. that parents were significantly more involved in disease management tasks than youth, although level of involvement varied by task. Decreased parent involvement was related to greater coping strategies used by patients, including massage, prayer, and positive thinking. Higher functional disability (lower functioning) was related to greater parent involvement in disease management tasks, suggesting that greater impairment may encourage increased parent involvement. Conclusions: Health professionals working with families of youth with SCD should discuss with parents and youth how disease management tasks and roles will be shared and transferred during adolescence. Parents and youth may also benefit from a discussion of these issues within their own families. AN - WOS:000287910000006 AU - Oliver-Carpenter, G. AU - Barach, I. AU - Crosby, L. E. AU - Valenzuela, J. AU - Mitchell, M. J. DA - Feb DO - 10.1016/s0027-9684(15)30262-5 IS - 2 N1 - Oliver-Carpenter, Gloria Barach, Ilana Crosby, Lori E. Valenzuela, Jessica Mitchell, Monica J. Valenzuela, Jessica/AAB-8760-2020; Hanghoj, Signe/E-2440-2012 Valenzuela, Jessica/0000-0002-4138-0949 PY - 2011 SN - 0027-9684 SP - 131-137 ST - Disease Management, Coping, and Functional Disability in Pediatric Sickle Cell Disease T2 - Journal of the National Medical Association TI - Disease Management, Coping, and Functional Disability in Pediatric Sickle Cell Disease UR - ://WOS:000287910000006 VL - 103 ID - 2511 ER - TY - JOUR AB - Migraine may affect as many as 9% of all schoolchildren and often presents with abdominal symptoms of pain, nausea, and vomiting. Even though the pathophysiology of migraine remains unknown, self-regulation techniques appear to be more effective in prevention of childhood migraine than conventional pharmacotherapy which is often associated with adverse effects. Mast cells have been implicated in the pathogenesis of migraine in adults, but have not been previously studied in children with migraine. Mast cells are found close to the vessels and nerves in the meninges where they can release multiple vasoactive, neurosensitizing, and pro-inflammatory mediators. Therefore, we investigated whether children with migraine may have increased urinary levels of mast cell mediators and whether practicing relaxation imagery exercises has an effect on the frequency of headache, as well as on mast cell activation. Urine was collected for 24 hours from children with and without migraine after a 5-day amine-restricted diet. Children with migraine also collected urine during migraine episodes. The mean levels of urinary histamine, its main metabolite, methylhistamine, and the mast cell enzyme, tryptase, were higher in children than generally found in adults, but they did not differ statistically in any of the categories studied. However, in 8 of 10 children who practiced relaxation imagery techniques and successfully reduced the number of migraines, the urine tryptase levels were also significantly lower. There was no relationship between successful practice and sex or age of the child. These results suggest that stress may activate mast cells which could be involved in the pathophysiology of migraine. AN - WOS:000081168800003 AU - Olness, K. AU - Hall, H. AU - Rozniecki, J. J. AU - Schmidt, W. AU - Theoharides, T. C. DA - Feb DO - 10.1046/j.1526-4610.1999.3902101.x IS - 2 N1 - Olness, K Hall, H Rozniecki, JJ Schmidt, W Theoharides, TC Theoharides, Theoharis C/E-5596-2010 PY - 1999 SN - 0017-8748 SP - 101-107 ST - Mast cell activation in children with migraine before and after training in self-regulation T2 - Headache TI - Mast cell activation in children with migraine before and after training in self-regulation UR - ://WOS:000081168800003 VL - 39 ID - 2884 ER - TY - JOUR AB - Background Although survivors of childhood cancer are at risk of chronic pain, the impact of pain on daily functioning is not well understood. Methods A total of 2836 survivors (mean age, 32.2 years [SD, 8.5 years]; mean time since diagnosis, 23.7 years [SD, 8.2 years]) and 343 noncancer community controls (mean age, 35.5 years [SD, 10.2 years]) underwent comprehensive medical, neurocognitive, and physical performance assessments, and completed measures of pain, health-related quality of life (HRQOL), and social functioning. Multinomial logistic regression models, using odds ratios and 95% confidence intervals (95% CIs), examined associations between diagnosis, treatment exposures, chronic health conditions, and pain. Relative risks (RRs) between pain and neurocognition, physical performance, social functioning, and HRQOL were examined using modified Poisson regression. Results Approximately 18% of survivors (95% CI, 16.1%-18.9%) versus 8% of controls (95% CI, 5.0%-10.9%) reported moderate to very severe pain with moderate to extreme daily interference (P < .001). Severe and life-threatening chronic health conditions were associated with an increased likelihood of pain with interference (odds ratio, 2.03; 95% CI, 1.62-2.54). Pain with daily interference was found to be associated with an increased risk of impaired neurocognition (attention: RR, 1.88 [95% CI, 1.46-2.41]; and memory: RR, 1.65 [95% CI, 1.25-2.17]), physical functioning (aerobic capacity: RR, 2.29 [95% CI, 1.84-2.84]; and mobility: RR, 1.71 [95% CI, 1.42-2.06]), social functioning (inability to hold a job and/or attend school: RR, 4.46 [95% CI, 3.45-5.76]; and assistance with routine and/or personal care needs: RR, 5.64 [95% CI, 3.92-8.10]), and HRQOL (physical: RR, 6.34 [95% CI, 5.04-7.98]; and emotional: RR, 2.83 [95% CI, 2.28-3.50]). Conclusions Survivors of childhood cancer are at risk of pain and associated functional impairments. Survivors should be screened routinely for pain and interventions targeting pain interference are needed. AN - WOS:000603054100001 AU - Olsson, I. T. AU - Alberts, N. M. AU - Li, C. H. AU - Ehrhardt, M. J. AU - Mulrooney, D. A. AU - Liu, W. AU - Pappo, A. S. AU - Bishop, M. W. AU - Anghelescu, D. L. AU - Srivastava, D. AU - Robison, L. L. AU - Hudson, M. M. AU - Ness, K. K. AU - Krull, K. R. AU - Brinkman, T. M. DA - May DO - 10.1002/cncr.33303 IS - 10 N1 - Olsson, Ingrid Tonning Alberts, Nicole M. Li, Chenghong Ehrhardt, Matthew J. Mulrooney, Daniel A. Liu, Wei Pappo, Alberto S. Bishop, Michael W. Anghelescu, Doralina L. Srivastava, Deokumar Robison, Leslie L. Hudson, Melissa M. Ness, Kirsten K. Krull, Kevin R. Brinkman, Tara M. Bishop, Michael/N-8133-2018 Bishop, Michael/0000-0003-3926-1446 1097-0142 PY - 2021 SN - 0008-543X SP - 1679-1689 ST - Pain and functional outcomes in adult survivors of childhood cancer: A report from the St. Jude Lifetime Cohort study T2 - Cancer TI - Pain and functional outcomes in adult survivors of childhood cancer: A report from the St. Jude Lifetime Cohort study UR - ://WOS:000603054100001 VL - 127 ID - 1776 ER - TY - JOUR AB - The aim of this study was to quantify the effect of tonsillectomy on the incidence of sore throats and its co-morbidity in adult patients. One hundred and nineteen adult patients were sent a standard questionnaire regarding their symptoms in the 12 months preceding and following their tonsillectomy. Outcome measures included the incidence of sore throats, total number of days with sore throat, amount of time taken off work or school, and number of visits to the general practitioner (GP). In addition, patients were asked to indicate the duration of their symptoms and whether or not they found the tonsillectomy effective in curing their sore throats. Sixty-six patients (55.5 per cent) returned completed questionnaires. The age of the patients ranged from 16 to 39 years. The mean duration of symptoms was 8.3 years. On average, patients had 8.1 different sore throat episodes, 42 sore throat days, 21.4 days of sore throat related absence from work or school, and 5.9 visits to the GP in the 12 months before their operation. For the 12 months after surgery, these reduced to 0.9 episodes, four days, 2.2 days and 0.6 visits, respectively. This reduction was very significant (p < 0.001, Wilcoxon signed rank test). After their surgery, more than half the patients achieved complete resolution of all the measured parameters mentioned above. Most of the remaining patients achieved at least 50 per cent resolution. Only three patients (4.8 per cent) achieved less than 50 per cent resolution. Ninety-five per cent of the patients found the operation effective in curing their sore throats and were glad they had had surgery. In conclusion, retrospective questionnaire data must be interpreted with some caution, but this study suggests that tonsillectomy is effective in reducing the incidence, duration and co-morbidity of recurrent sore throats in adults; this must be balanced against the post-operative problems in a minority of patients. AD - Department of Otolaryngology/Head and Neck Surgery, Southmead Hospital, Bristol, UK. oluwasanmiadenike@hotmail.com AN - 16917984 AU - Oluwasanmi, A. F. AU - Thornton, M. R. AU - Khalil, H. S. AU - Tierney, P. A. DA - Feb DO - 10.1017/s0022215105002197 DP - NLM ET - 2006/08/19 IS - 2 KW - Adolescent Adult Attitude to Health England/epidemiology Female Humans Incidence Length of Stay Male Pain, Postoperative/epidemiology Pharyngitis/epidemiology/*surgery Postoperative Complications Postoperative Hemorrhage/epidemiology Recurrence Surveys and Questionnaires *Tonsillectomy Treatment Outcome LA - eng N1 - Oluwasanmi, Adenike Folake Thornton, Martin Robert Khalil, Hisham Saleh Tierney, Paul Anthony Journal Article England J Laryngol Otol. 2006 Feb;120(2):e7. doi: 10.1017/s0022215105002197. PY - 2006 SN - 0022-2151 (Print) 0022-2151 SP - e7 ST - Effect of tonsillectomy on recurrent sore throats in adults: patients' perspectives T2 - J Laryngol Otol TI - Effect of tonsillectomy on recurrent sore throats in adults: patients' perspectives VL - 120 ID - 3711 ER - TY - JOUR AB - OBJECTIVE: A stated goal of the preparticipation physical evaluation (PPE) is to reduce musculoskeletal injury, yet the musculoskeletal portion of the PPE is reportedly of questionable use in assessing lower extremity injury risk in high school-aged athletes. The objectives of this study are: (1) identify clinical assessment tools demonstrated to effectively determine lower extremity injury risk in a prospective setting, and (2) critically assess the methodological quality of prospective lower extremity risk assessment studies that use these tools. DATA SOURCES: A systematic search was performed in PubMed, CINAHL, UptoDate, Google Scholar, Cochrane Reviews, and SportDiscus. Inclusion criteria were prospective injury risk assessment studies involving athletes primarily ages 13 to 19 that used screening methods that did not require highly specialized equipment. Methodological quality was evaluated with a modified physiotherapy evidence database (PEDro) scale. MAIN RESULTS: Nine studies were included. The mean modified PEDro score was 6.0/10 (SD, 1.5). Multidirectional balance (odds ratio [OR], 3.0; CI, 1.5-6.1; P < 0.05) and physical maturation status (P < 0.05) were predictive of overall injury risk, knee hyperextension was predictive of anterior cruciate ligament injury (OR, 5.0; CI, 1.2-18.4; P < 0.05), hip external:internal rotator strength ratio of patellofemoral pain syndrome (P = 0.02), and foot posture index of ankle sprain (r = -0.339, P = 0.008). CONCLUSIONS: Minimal prospective evidence supports or refutes the use of the functional musculoskeletal exam portion of the current PPE to assess lower extremity injury risk in high school athletes. Limited evidence does support inclusion of multidirectional balance assessment and physical maturation status in a musculoskeletal exam as both are generalizable risk factors for lower extremity injury. AD - *Division of Athletic Training, The Ohio State University School of Health and Rehabilitation Sciences, Columbus, Ohio; †Family Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio; ‡Sports Health and Performance Institute, The Ohio State University Wexner Medical Center, Columbus, Ohio; and §Division of Physical Therapy, The Ohio State University School of Health and Rehabilitation Sciences, Columbus, Ohio. AN - 26978166 AU - Onate, J. A. AU - Everhart, J. S. AU - Clifton, D. R. AU - Best, T. M. AU - Borchers, J. R. AU - Chaudhari, A. M. C2 - PMC5122462 C6 - NIHMS829011 DA - Nov DO - 10.1097/jsm.0000000000000284 DP - NLM ET - 2016/10/27 IS - 6 KW - Adolescent Adolescent Development Humans *Leg Injuries Muscle Strength Physical Examination/*methods Postural Balance Risk Factors LA - eng N1 - 1536-3724 Onate, James A Everhart, Joshua S Clifton, Daniel R Best, Thomas M Borchers, James R Chaudhari, Ajit M W R01 AR062578/AR/NIAMS NIH HHS/United States Journal Article Review Systematic Review Clin J Sport Med. 2016 Nov;26(6):435-444. doi: 10.1097/JSM.0000000000000284. PY - 2016 SN - 1050-642X (Print) 1050-642x SP - 435-444 ST - Physical Exam Risk Factors for Lower Extremity Injury in High School Athletes: A Systematic Review T2 - Clin J Sport Med TI - Physical Exam Risk Factors for Lower Extremity Injury in High School Athletes: A Systematic Review VL - 26 ID - 4056 ER - TY - JOUR AB - BACKGROUND: Primary Headaches (H) and Learning Disabilities (LD) are frequent in childhood and can coexist in the same subject, but their correlation is not always clear. Aim of our study is to evaluate these relationship considering also any psychopathologies and their influence on the quality of life by considering an aspect such as school absences. METHODS: 193 children (8-18y) with H and LD assessed consecutively at the Headache Center of L'Aquila, from 2013 to 2018 are the sample. School problems were evaluated by Italian batteries for LD; psychopathology screening by clinical interview and SAFA test. The sample was divided into 3 Groups [Group 1: patients with H (n = 122), Group 2: patients with LD (n = 37), Group 3: patients with H + LD (n = 34)] in order to compare subjects with H and LD vs subjects having only one disorder. RESULTS: The most prevalent headache diagnosis was Migraine without Aura, but Chronic Tension Headache (CTH) showed a stronger impact on quality of life. LD have a higher prevalence in our sample (9.44%) than in general Italian population (3.2%). In Group 3 was higher prevalence of anxiety disorders (p = 0.050) and 50% of patients with CTH was absent from school due to headache. CONCLUSIONS: LD can be related to headache chronicization and to a higher prevalence of psychopathologies and school absences, so an early diagnosis of LD in patients with H is crucial to prevent the worsening of the headache itself and of quality of life. AD - Department of Life, Health and Environmental Sciences, Neuropsychiatric Clinic, Headache Centre, San Salvatore Hospital of L'Aquila, University of L'Aquila, L'Aquila, Italy. Neuropsychiatric Clinic, San Salvatore Hospital of L'Aquila, L'Aquila, Italy. Department of Life, Health and Environmental Sciences, Neuropsychiatric Clinic, Headache Centre, San Salvatore Hospital of L'Aquila, University of L'Aquila, L'Aquila, Italy - elisabetta.tozzi@univaq.it. AN - 33858130 AU - Onofri, A. AU - Olivieri, L. AU - Silva, P. AU - Bernassola, M. AU - Tozzi, E. DA - Apr 15 DO - 10.23736/s2724-5276.21.06191-7 DP - NLM ET - 2021/04/17 LA - eng N1 - 2724-5780 Onofri, Agnese Olivieri, Luca Silva, Pamela Bernassola, Michela Tozzi, Elisabetta Journal Article Minerva Pediatr (Torino). 2021 Apr 15. doi: 10.23736/S2724-5276.21.06191-7. PY - 2021 SN - 2724-5780 ST - Correlation between primary headaches and learning disabilities in children and adolescents T2 - Minerva Pediatr (Torino) TI - Correlation between primary headaches and learning disabilities in children and adolescents ID - 4188 ER - TY - JOUR AB - PURPOSE: The aim of this study was to investigate the prevalence of acute low back pain (ALBP) and associated factors in high school students from a Southern Brazilian city. METHODS: The study was cross-sectional and interviewed 1,233 students 13- to 19-year-olds, attending high schools. A total of 25 schools were included in the sample (15 state institutions, 7 private, 2 federal and 1 municipal). The ALBP was evaluated using two questions. The outcome was LBP in the previous 30 days. RESULTS: The prevalence of ALBP was 13.7%. Non-white students, who commuted to school walking, showed a higher prevalence of ALBP. The prevalence of ALBP is relatively high. CONCLUSIONS: Further studies with follow-ups to adulthood are needed to investigate whether physical cumulative loads on the lumbar spine (for example, duration/transport, school bags and inadequate school furniture) during adolescence, may influence the development of ALBP later in life. AU - Onofrio, Antonio Carlos AU - da Silva, Marcelo Cozzensa AU - Domingues, Marlos Rodrigues AU - Rombaldi, Airton José DA - 2012/07// DO - 10.1007/s00586-011-2056-3 DP - PubMed IS - 7 J2 - Eur Spine J KW - Adolescent Body Mass Index Brazil Cross-Sectional Studies Ergonomics Female Humans Low Back Pain Male Motor Activity Nutritional Status Prevalence Schools Smoking Social Class Transportation Weight-Bearing Young Adult LA - eng PY - 2012 SN - 1432-0932 SP - 1234-1240 ST - Acute low back pain in high school adolescents in Southern Brazil T2 - European Spine Journal: Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society TI - Acute low back pain in high school adolescents in Southern Brazil: prevalence and associated factors UR - http://www.ncbi.nlm.nih.gov/pubmed/22048405 VL - 21 ID - 101 ER - TY - JOUR AB - Ethnic disparities in labor pain management exist. Our purpose is to identify patients' attitudes and beliefs about epidural analgesia in order to develop a culturally competent educational intervention. A prospective observational study was conducted in patients admitted for vaginal delivery between July 1st-31st, 2009. Inclusion criteria were: singleton, term, cephalic, normal fetal heart tracing and no contraindications for epidural. Patients were surveyed regarding their wishes for analgesia, and their reasons for declining epidural. The obstetrics physician performed pain management counseling as is usually done. Patients were asked again about their choice for analgesia. Likert scale questionnaires were used. Wilcoxon signed ranked test was used for categorical variables. Logistic regression was performed to look for predictors of epidural request. Fifty patients were interviewed. Average age was (27.9 ± 6.7), gestational age (39.3 ± 1.3), and a median parity of 2 (range 0-6). 72% declined epidural upon admission, and 61% after counseling (P = 0.14). Most common reasons for declined epidural were 'women should cope with labor pain' (57%), 'fear of back pain' (54%) and 'family/friends advise against epidural' (36%). Acculturation was assessed by years living in the US (10 ± 6.3), preferred language (Spanish 80%) and ethnic self-identification (Hispanic 98%). 38% were high school graduates. In multivariate logistic regression, graduation from high school was the only variable associated to request for epidural in labor (OR 4.94, 95% CI 1.6-15.1). Educational level is associated to requesting an epidural in labor. Knowledge of patients' fears and expectations is essential to develop adequate counseling interventions. AD - Department of Obstetrics and Gynecology, University of Texas Health Science Center at Houston, Houston, TX 77026, USA. Francisco.J.Orejuela@uth.tmc.edu AN - 21267656 AU - Orejuela, F. J. AU - Garcia, T. AU - Green, C. AU - Kilpatrick, C. AU - Guzman, S. AU - Blackwell, S. DA - Apr DO - 10.1007/s10903-011-9440-2 DP - NLM ET - 2011/01/27 IS - 2 KW - Acculturation Adult Analgesia, Epidural/*statistics & numerical data Cultural Characteristics Cultural Competency Delivery, Obstetric Female *Hispanic Americans Humans Labor Pain/*ethnology Labor, Obstetric/*ethnology Patient Admission/*statistics & numerical data Patient Education as Topic/*methods Pregnancy Prenatal Care/statistics & numerical data Prospective Studies Young Adult LA - eng N1 - 1557-1920 Orejuela, Francisco J Garcia, Tiffany Green, Charles Kilpatrick, Charlie Guzman, Sara Blackwell, Sean Journal Article United States J Immigr Minor Health. 2012 Apr;14(2):287-91. doi: 10.1007/s10903-011-9440-2. PY - 2012 SN - 1557-1912 SP - 287-91 ST - Exploring factors influencing patient request for epidural analgesia on admission to labor and delivery in a predominantly Latino population T2 - J Immigr Minor Health TI - Exploring factors influencing patient request for epidural analgesia on admission to labor and delivery in a predominantly Latino population VL - 14 ID - 4226 ER - TY - JOUR AB - The prevalence rate and other aspects of migraine were investigated among school children (aged 6-13 years) in Enugu. The diagnosis of migraine was made by means of a questionnaire completed by parents which was based on the criteria proposed by Prensky and Sommer, and was further confirmed by personal interview of the parents in their homes. A prevalence rate of 6.8% was found among the 4,398 schoolchildren studied. More girls were affected than boys (158 and 140 respectively). Most (88.4%) of the children had their first attack by 10 years of age. Attacks occurred mostly in the afternoon, with sunlight and exercise as the most important trigger factors. Headache of a throbbing nature, sensory aura and relief after sleep were the commonest symptoms. Clinical examination was abnormal in only one child who had paralytic poliomyelitis, but EEG abnormalities were found in 51.1% of the children who had the test. The study revealed a hitterto unrecognised high level of morbidity from migraine among school children in Enugu, resulting in a disturbingly high incidence of school absenteeism. AD - Department of Paediatrics, University of Nigeria Teaching Hospital, Enugu, Nigeria. AN - 9473955 AU - Orji, G. I. AU - Iloeje, S. O. DA - Oct-Dec DP - NLM ET - 1998/02/25 IS - 4 KW - Adolescent Age of Onset Child Electroencephalography Female Humans Male Migraine Disorders/diagnosis/*epidemiology Morbidity Nigeria/epidemiology Pilot Projects Prevalence LA - eng N1 - Orji, G I Iloeje, S O Journal Article Nigeria West Afr J Med. 1997 Oct-Dec;16(4):208-17. PY - 1997 SN - 0189-160X (Print) 0189-160x SP - 208-17 ST - Childhood migraine in Nigeria--I: A community-based study T2 - West Afr J Med TI - Childhood migraine in Nigeria--I: A community-based study VL - 16 ID - 3432 ER - TY - JOUR AB - Background: The proportion of Swedish schoolchildren that reports psychosomatic complaints has increased during recent decades, parallel to major structural changes in Swedish society. Aim: To investigate the association of psychosomatic complaints in relation to household socio-economic conditions. Methods: Cross-sectional study based on data from child supplements linked to nationally representative household surveys in Sweden during 2000-2003, covering a sample of 5390 children aged 10-18 y. Symptom variables were based on child interviews, while data from parental interviews were used to create socio-economic variables. Results : Girls more often reported headache and recurrent abdominal pain (RAP) than boys, and these differences became more pronounced with age. Economic stress in the household was associated with headache (OR 1.21, p < 0.05), RAP (OR 1.46, p < 0.001) as well as difficulties falling asleep (OR 1.35, p < 0.01), while there were no consistent associations between symptoms and social class or unemployed parents. Children in single-parent families consistently reported somewhat more symptoms than children in two-parent families ( OR 1.26 for at least two of the three symptoms, p < 0.05). AN - WOS:000239953000007 AU - Ostberg, V. AU - Alfven, G. AU - Hjern, A. DA - Aug DO - 10.1080/08035250600636545 IS - 8 N1 - Ostberg, Viveca Alfven, Gosta Hjern, Anders Hjern, Anders/0000-0002-1645-2058 1651-2227 PY - 2006 SN - 0803-5253 SP - 929-934 ST - Living conditions and psychosomatic complaints in Swedish schoolchildren T2 - Acta Paediatrica TI - Living conditions and psychosomatic complaints in Swedish schoolchildren UR - ://WOS:000239953000007 VL - 95 ID - 2723 ER - TY - JOUR AB - Bullying involves repeated exposure to negative actions while also invoking a power asymmetry between the involved parties. From a stress perspective, being bullied can be seen as a severe and chronic stressor, and an everyday social-evaluative threat, coupled with a shortage of effective social resources for dealing with this particular stressor. The aim of this study was to investigate whether exposure to bullying among mid-adolescent girls and boys is associated with subjective and objective stress-related outcomes in terms of perceived stress, recurrent pain, and salivary cortisol. The data came from the School Stress and Support Study (TriSSS) including students in grades 8-9 in two schools in Stockholm, Sweden, in 2010 (study sample n = 392; cortisol subsample n = 198). Bullying was self-reported and measured by multiple items. The statistical analyses included binary logistic and linear (OLS) regression. Being bullied was associated with greater perceived stress and an increased risk of recurrent pain, among both boys and girls. Also, bullied students had lower cortisol output (AUCG) and lower cortisol awakening response (CARG) as compared to those who were not bullied. Gender-stratified analyses demonstrated that these associations were statistically significant for boys but not for girls. In conclusion, this study demonstrated that being bullied was related to both subjective and objective stress markers among mid-adolescent girls and boys, pointing to the necessity of continuously working against bullying. AN - WOS:000426721400189 AU - Ostberg, V. AU - Laftman, S. B. AU - Modin, B. AU - Lindfors, P. C7 - 364 DA - Feb DO - 10.3390/ijerph15020364 IS - 2 N1 - Ostberg, Viveca Laftman, Sara B. Modin, Bitte Lindfors, Petra PY - 2018 SN - 1660-4601 ST - Bullying as a Stressor in Mid-Adolescent Girls and Boys-Associations with Perceived Stress, Recurrent Pain, and Salivary Cortisol T2 - International Journal of Environmental Research and Public Health TI - Bullying as a Stressor in Mid-Adolescent Girls and Boys-Associations with Perceived Stress, Recurrent Pain, and Salivary Cortisol UR - ://WOS:000426721400189 VL - 15 ID - 2034 ER - TY - JOUR AB - Stress, and stress-related health complaints, are common among young people, especially girls. Since studies have shown that school demands are an important driver of stress in adolescents, identifying if school-based resources can protect against stress is highly relevant. The aim of this study was to analyse task-related demands and task-related coping resources as aspects of the school work environment of potential relevance for stress in mid-adolescent girls and boys. The data came from "The School Stress and Support study" (TriSSS) conducted among students in grades 8 and 9 (aged 14-16 years). Self-reports of demands, coping resources, stress, as well as recurrent pain, were collected through questionnaires (n = 411). A subsample of students (n = 191-198) also provided salivary samples, which were analysed for the stress marker cortisol. Linear (OLS) and binary logistic regression analyses showed that higher demands were associated with more perceived stress, a higher likelihood of recurrent pain, and a lower cortisol awakening response. Greater coping resources were associated with less perceived stress and a lower likelihood of recurrent pain, but there was no association with cortisol. The strength of the associations differed by gender. The findings suggest that schools can promote student wellbeing by providing clear and timely information and teacher support to the students, especially for boys. Identifying specific features of the schoolwork that give rise to stress and to modify these accordingly is also of importance, especially for girls. AN - WOS:000448818100085 AU - Ostberg, V. AU - Plenty, S. AU - Laftman, S. B. AU - Modin, B. AU - Lindfors, P. C7 - 2143 DA - Oct DO - 10.3390/ijerph15102143 IS - 10 N1 - Ostberg, Viveca Plenty, Stephanie Laftman, Sara B. Modin, Bitte Lindfors, Petra PY - 2018 SN - 1660-4601 ST - School Demands and Coping Resources - Associations with Multiple Measures of Stress in Mid-Adolescent Girls and Boys T2 - International Journal of Environmental Research and Public Health TI - School Demands and Coping Resources - Associations with Multiple Measures of Stress in Mid-Adolescent Girls and Boys UR - ://WOS:000448818100085 VL - 15 ID - 1988 ER - TY - JOUR AB - Evaluated the outcome of a combined behavioral therapy, comprising relaxation training, temperature biofeedback, and cognitive training, administered in a school setting, at posttreatment, and 7-month follow-up, on a group of schoolchildren with migraine. Comparison between the experimental group (n = 32) and the waiting-list control group (n = 9) showed a treatment effect on headache frequency and duration but not on intensity. Using a 50% reduction in the headache activity as a criterion for clinical improvement, 45% of the children in the experimental group were clinically improved at the end of the treatment. The treated subjects were found to have maintained significant improvement at follow-up. Sex, headache history, age, and psychosomatic complaints before the training emerged as predictors of outcome. A decrease in state anxiety and an increase in the ability to relax during the sessions contributed to headache improvement. Finally, the acquired capacity to raise one's finger temperature during the biofeedback sessions was related to headache reduction after the training. AD - Department of Psychophysiology, Vrije Universiteit, Amsterdam, The Netherlands. AN - 8138865 AU - Osterhaus, S. O. AU - Passchier, J. AU - van der Helm-Hylkema, H. AU - de Jong, K. T. AU - Orlebeke, J. F. AU - de Grauw, A. J. AU - Dekker, P. H. DA - Dec DO - 10.1093/jpepsy/18.6.697 DP - NLM ET - 1993/12/01 IS - 6 KW - Adolescent *Arousal Behavior Therapy/*methods Biofeedback, Psychology/methods Child Cognitive Behavioral Therapy/methods Combined Modality Therapy Female Humans Male Migraine Disorders/psychology/*therapy Relaxation Therapy Skin Temperature LA - eng N1 - Osterhaus, S O Passchier, J van der Helm-Hylkema, H de Jong, K T Orlebeke, J F de Grauw, A J Dekker, P H Clinical Trial Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't United States J Pediatr Psychol. 1993 Dec;18(6):697-715. doi: 10.1093/jpepsy/18.6.697. PY - 1993 SN - 0146-8693 (Print) 0146-8693 SP - 697-715 ST - Effects of behavioral psychophysiological treatment on schoolchildren with migraine in a nonclinical setting: predictors and process variables T2 - J Pediatr Psychol TI - Effects of behavioral psychophysiological treatment on schoolchildren with migraine in a nonclinical setting: predictors and process variables VL - 18 ID - 3501 ER - TY - JOUR AB - Primary headache and functional abdominal pain prevalences in an unselected population-based sample of German preschool children and their parents (n=885) were collected in relation to health-related quality of life and sociodemographic variables. The pain symptoms were assessed according to IHS classification (2004) and Rome-II criteria (1999) during the 2004 data census. The participation rate was 62.7%, with an equal gender distribution. The focus of this paper lies on the symptom-oriented point prevalences for primary headaches of preschool children: 3.6% headache, 33.2% abdominal pain, 48.8% headache+abdominal pain and 14.4% without pain. High comorbidities for pain-affected children have been found. Pain intensities differ significantly only for abdominal pain (one-way ANOVA F=3,339, df=4/445, p=0.010*), not for headaches. However, recurrent headaches show a striking ratio in favour of boys (10:1). Children at preschool age have high quality-of-life measures, already influenced negatively by paediatric pain experiences (one-way ANOVA: F=9,193, df=4/546, p=0.000**). Headache and abdominal pain are relevant for children's everyday life; hence, simultaneous and prospective assessment is an essential issue in public health research. AD - Department of Neurology, Medical Faculty, University Duisburg - Essen, Essen, Germany. gabriele.ostkirchen@uni-essen.de AN - 17058045 AU - Ostkirchen, G. G. AU - Andler, F. AU - Hammer, F. AU - Pöhler, K. D. AU - Snyder-Schendel, E. AU - Werner, N. K. AU - Markett, S. AU - Horacek, U. AU - Jöckel, K. H. AU - Diener, H. C. C2 - PMC3468182 DA - Oct DO - 10.1007/s10194-006-0325-z DP - NLM ET - 2006/10/24 IS - 5 KW - Abdominal Pain/*epidemiology/*physiopathology Analysis of Variance Child Child, Preschool Comorbidity Female Germany/epidemiology Headache/*epidemiology/*physiopathology Health Surveys Humans Male Prevalence Quality of Life Recurrence Socioeconomic Factors Surveys and Questionnaires LA - eng N1 - 1129-2377 Ostkirchen, Gabriele Gerda Andler, Felix Hammer, Friederike Pöhler, Kerstin Daniela Snyder-Schendel, Erika Werner, Nina Kerstin Markett, Sebastian Horacek, Ulrike Jöckel, Karl-Heinz Diener, Hans Christoph Journal Article J Headache Pain. 2006 Oct;7(5):331-40. doi: 10.1007/s10194-006-0325-z. Epub 2006 Oct 25. PY - 2006 SN - 1129-2369 (Print) 1129-2369 SP - 331-40 ST - Prevalences of primary headache symptoms at school-entry: a population-based epidemiological survey of preschool children in Germany T2 - J Headache Pain TI - Prevalences of primary headache symptoms at school-entry: a population-based epidemiological survey of preschool children in Germany VL - 7 ID - 3292 ER - TY - JOUR AB - Background Adverse childhood experiences (ACEs) affect adult mental health and tend to contribute to greater symptoms of depression and more frequent suicide attempts. Given the relationship between symptoms of depression and patient-reported outcomes (PROs), adversity in childhood might be associated with PROs in patients seeking care for musculoskeletal problems, but it is not clear whether in fact there is such an association among patients seeking care in an outpatient, upper extremity orthopaedic practice. Questions/purposes (1) Are ACE scores independently associated with variation in physical limitations measured among patients seen by an orthopaedic surgeon? (2) Are ACE scores independently associated with variations in pain intensity? (3) What factors are associated with ACE scores when treated as a continuous variable or as a categorical variable? Methods We prospectively enrolled 143 adult patients visiting one of seven participating orthopaedic surgeons at three private and one academic orthopaedic surgery offices in a large urban area. We recorded their demographics and measured ACEs (using a validated 10-item binary questionnaire that measured physical, emotional, and sexual abuse in the first 18 years of life), magnitude of physical limitations, pain intensity, symptoms of depression, catastrophic thinking, and health anxiety. There were 143 patients with a mean age of 51 years, 62 (43%) of whom were men. In addition, 112 (78%) presented with a specific diagnosis and most (n = 79 [55%]) had upper extremity symptoms. We created one logistic and three linear regression models to test whether age, gender, race, marital status, having children, level of education, work status, insurance type, comorbidities, body mass index, smoking, site of symptoms, type of diagnosis, symptoms of depression, catastrophic thinking, and health anxiety were independently associated with (1) the magnitude of limitations; (2) pain intensity; (3) ACE scores on the continuum; and (4) ACE scores categorized (< 3 or $ 3). We calculated a priori that to detect a medium effect size with 90% statistical power and a set at 0.05, a sample of 136 patients was needed for a regression with five predictors if ACEs would account for $ 5% of the variability in physical function, and our complete model would account for 15% of the overall variability. To account for 5% incomplete responses, we enrolled 143 patients. Results We found no association between ACE scores and the magnitude of physical limitations measured by Patient-Reported Outcomes Measurement Information System Physical Function (p = 0.67; adjusted R2 = 0.55). ACE scores were not independently associated with pain intensity (Pearson correlation [r] = 0.11; p = 0.18). Greater ACE scores were independently associated with diagnosed mental comorbidities both when analyzed on the continuum (regression coefficient [b] = 1.1; 95% confidence interval [CI], 0.32-1.9; standard error [SE] 0.41; p = 0.006) and categorized (odds ratio [OR], 3.3; 95% CI, 1.2-9.2; SE 1.7; p = 0.024), but not with greater levels of health anxiety (OR, 1.1; 95% CI, 0.90-1.3; SE 0.096; p = 0.44, C statistic = 0.71), symptoms of depression (ACE < 3 mean 6 SD = 0.73 6 1.4; ACE $ 3 = 1.0 6 1.4; p = 0.29) or catastrophic thinking (ACE < 3 = 3.663.5; ACE$ 3 = 4.9 6 5.1; p = 0.88). Conclusions ACEs may not contribute to greater pain intensity or magnitude of physical limitations unless they are accompanied by greater health anxiety or less effective coping strategies. Adverse events can contribute to anxiety and depression, but perhaps they sometimes lead to development of resilience and effective coping strategies. Future research might address whether ACEs affect symptoms and limitations in younger adult patients and patients with more severe musculoskeletal pathology such as major traumatic injuries. Level of Evidence Level II, prognostic study. AN - WOS:000472543100036 AU - Ottenhoff, J. S. E. AU - Kortlever, J. T. P. AU - Boersma, E. Z. AU - Laverty, D. C. AU - Ring, D. AU - Driscoll, M. D. DA - Jan DO - 10.1097/corr.0000000000000519 IS - 1 N1 - Ottenhoff, Janna S. E. Kortlever, Joost T. P. Boersma, Emily Z. Laverty, David C. Ring, David Driscoll, Matthew D. Boersma, Emily/0000-0001-5947-5316; Kortlever, Joost/0000-0003-3825-5546 1528-1132 PY - 2019 SN - 0009-921X SP - 219-228 ST - Adverse Childhood Experiences Are Not Associated With Patient-reported Outcome Measures in Patients With Musculoskeletal Illness T2 - Clinical Orthopaedics and Related Research TI - Adverse Childhood Experiences Are Not Associated With Patient-reported Outcome Measures in Patients With Musculoskeletal Illness UR - ://WOS:000472543100036 VL - 477 ID - 1965 ER - TY - JOUR AB - Introduction: Hemophilia is a genetic disorder in which recurrent joint bleeding causes arthropathy. Inflammation and degeneration play roles in the pathogenesis of hemophilic arthropathy. Patients with juvenile idiopathic arthritis (JIA) experience a similar inflammatory degenerative joint disease. A comparison of different patients with common pathogenetic features may identify unique features helpful in terms of the follow-up. Aim: We compared the quality of life (QoL) of patients with hemophilia and JIA, and healthy controls, using a generic QoL scale, Kidscreen and Disabkids Questionnaires (KINDL). Differences among groups were evaluated in terms of sociodemographic characteristics and clinical parameters affecting the QoL. Methods: We included 33 hemophilia patients, 19 JIA patients, and 32 healthy individuals aged 4 to 18 years. Sociodemographic characteristics (the age, the maternal educational status, the place of residence, the size of the household, the household income, divorced parents) were noted, and the KINDL was administered to all participants. Clinical parameters associated with arthropathy (the functional independence score [FISH], the hemophilia joint health score [HJHS], the arthropathic joint count, and the painful joint count) were documented. Differences in frequencies and medians among the groups were evaluated using the (2), the Mann-Whitney U, and the Kruskal-Wallis tests. Results: All KINDL dimensions were above 50, reflecting good conditions in the 2 patient groups. No difference between patients with hemophilia and JIA was evident in terms of the clinical parameters of FISH, the HJHS, or the arthropathic or painful joint counts (P>0.05). Sociodemographically, only the frequency of literate mothers was lower in patients with hemophilia than in those with JIA and healthy controls (P=0.03). Patients with JIA scored more higher on the KINDL dimension of chronic illness than those with hemophilia (P=0.02). The FISH score correlated with the total QoL score in both patients with hemophilia and JIA (r=0.39, P=0.03 and r=0.48, P=0.04, respectively). Conclusions: Although no difference was evident between the patient groups in terms of clinical parameters associated with arthropathy, JIA patients coped better with illness than those with hemophilia. JIA patients had a higher proportion of literate mothers than hemophilia patients; this may affect a patient's ability to cope with issues relating to chronic illness. Implementation of an educational program for mothers of hemophilia patients, during follow-up, may improve the patient's QoL. Also, hemophilia patients should be assisted to improve their QoL in the dimensions of self-esteem and schooling. Lastly, the evaluation of functional disability by FISH in hemophilia patients is important because the FISH score correlated with the total QoL score, as revealed by KINDL. In JIA patients also, functional disabilities caused by arthropathy affected the QoL. AN - WOS:000364330200005 AU - Oymak, Y. AU - Kaygusuz, A. AU - Turedi, A. AU - Yaman, Y. AU - Eser, E. AU - Cubukcu, D. AU - Vergin, C. DA - Nov DO - 10.1097/mph.0000000000000429 IS - 8 N1 - Oymak, Yesim Kaygusuz, Arife Turedi, Aysen Yaman, Yontem Eser, Erhan Cubukcu, Duygu Vergin, Canan yaman, yontem/AAP-6828-2021 1536-3678 PY - 2015 SN - 1077-4114 SP - 600-604 ST - Comparing the Quality of Life of Patients With Hemophilia and Juvenile Idiopathic Arthritis in Which Chronic Arthropathy Is a Common Complication T2 - Journal of Pediatric Hematology Oncology TI - Comparing the Quality of Life of Patients With Hemophilia and Juvenile Idiopathic Arthritis in Which Chronic Arthropathy Is a Common Complication UR - ://WOS:000364330200005 VL - 37 ID - 2213 ER - TY - JOUR AB - BACKGROUND/AIM: To determine the frequency of migraine in the eastern part of Turkey and its sociodemographic characteristics, impact on disability, and clinical aspects. MATERIALS AND METHODS: The study was conducted door-to-door in the eastern part of Turkey. Those who suffered from headaches were diagnosed with migraine as per the 2004 diagnosis criteria of the International Headache Society and its frequency was determined. Demographic data and Migraine Disability Assessment Scale (MIDAS) scores were recorded. RESULTS: Of the individuals evaluated, 60.4% (883) suffered from headaches, of which 43.6% (637) were evaluated as nonmigraine and 16.8% (246) as migraine headaches. Migraine prevalence was detected to be 10.3% (75) in men and 23.1% (171) in women. When the MIDAS scale was considered, 7.3% of the patients were classified with mild pain, 36.9% with mild to moderate pain, 41% with moderate pain, and 14.6% with severe pain. CONCLUSION: Migraine headache has a wide and complex range of symptoms and is frequently observed in women and young adults. The prevalence of migraine among the general population of eastern Turkey was found to be similar to the averages in the rest of the country, as well to the averages of studies in Europe. AD - Department of Neurology, Atatürk University, Erzurum, Turkey. AN - 25551933 AU - Ozdemir, G. AU - Aygül, R. AU - Demir, R. AU - Ozel, L. AU - Ertekin, A. AU - Ulvi, H. DP - NLM ET - 2015/01/02 IS - 4 KW - Absenteeism Adolescent Adult Age Factors Cost of Illness Disability Evaluation Female Humans Male Middle Aged Migraine Disorders/diagnosis/*epidemiology Pain Measurement Prevalence Sex Factors Socioeconomic Factors Turkey/epidemiology Young Adult LA - eng N1 - Ozdemir, Gökhan Aygül, Recep Demir, Recep Ozel, Lütfi Ertekin, Ayfer Ulvi, Hizir Journal Article Turkey Turk J Med Sci. 2014;44(4):624-9. PY - 2014 SN - 1300-0144 (Print) 1300-0144 SP - 624-9 ST - Migraine prevalence, disability, and sociodemographic properties in the eastern region of Turkey: a population-based door-to-door survey T2 - Turk J Med Sci TI - Migraine prevalence, disability, and sociodemographic properties in the eastern region of Turkey: a population-based door-to-door survey VL - 44 ID - 3326 ER - TY - JOUR AB - AIM: The aims of this study were to investigate comorbid psychiatric disorders and to identify anxiety and depression levels and quality of life in children and adolescents with migraine; and to assess their relationship with migraine. METHOD: 35 patients aged 9-16 years were followed in our neurology clinic and their parents were included into the study. 35 age- and sex-matched patients were employed as the control group. In the subjects included, psychiatric disorders were assessed by using the Schedule for Affective Disorders and Schizophrenia for School Age Children-Present and Lifetime Version. All children and adolescents were assessed by using the Children's Depression Inventory, the State-Trait Anxiety Inventory and the Pediatric Quality of Life Inventory. In addition, the Pediatric Migraine Disability Assessment Tool and visual analog scale were used to identify the degree of disability and pain severity in patients with migraine. FINDINGS: In the psychiatric assessment of children and adolescents with migraine, it was found that a psychiatric diagnosis was made in 40% of patients; and depression scale scores were significantly higher than those of controls. Quality of life was found to be poorer in patients with migraine compared to controls. It was found that quality of life was negatively correlated with pain severity and degree of disability; while it was positively correlated with depression scores. DISCUSSION: In children and adolescents with migraine, treatment of psychiatric disorders in addition to migraine therapy can facilitate migraine management and may decrease the need for prophylactic therapy. AD - Child and Adolescent Psychiatry, Erciyes University School of Medicine, Kayseri, Turkey. Child and Adolescent Psychiatry, Elazığ Mental Health Hospital, Elazığ, Turkey bitasdelen@gmail.com. Department of Child Neurology, Faculty of Medicine, Firat University, Elazığ, Turkey. Department of Psychiatry, Erciyes University Medical School, Kayseri, Turkey. Department of Child Psychiatry, Erciyes University School of Medicine, Kayseri, Turkey. Child and Adolescent Psychiatry Department, School of Medicine, Muğla Sıtkı Koçman University, Muğla, Turkey. Department of Child Neurology, Erciyes University School of Medicine, Kayseri, Turkey. AN - 26759448 AU - Öztop, D. B. AU - Taşdelen, Bİ AU - PoyrazoğLu, H. G. AU - Ozsoy, S. AU - Yilmaz, R. AU - Şahın, N. AU - Per, H. AU - Bozkurt, S. DA - Jun DO - 10.1177/0883073815623635 DP - NLM ET - 2016/01/14 IS - 7 KW - Adolescent Anxiety/epidemiology Child Comorbidity Cross-Sectional Studies Depression/epidemiology Disability Evaluation Female Humans Interview, Psychological Male Mental Disorders/complications/epidemiology Migraine Disorders/complications/epidemiology/*psychology Pain/epidemiology/psychology Psychiatric Status Rating Scales Psychopathology *Quality of Life *adolescent *child *migraine *psychopathology LA - eng N1 - 1708-8283 Öztop, Didem Behice Taşdelen, Bedia İnce PoyrazoğLu, Hatıce Gamze Ozsoy, Saliha Yilmaz, Rabia Şahın, Nilfer Per, Hüseyin Bozkurt, Selma Journal Article United States J Child Neurol. 2016 Jun;31(7):837-42. doi: 10.1177/0883073815623635. Epub 2016 Jan 12. PY - 2016 SN - 0883-0738 SP - 837-42 ST - Assessment of Psychopathology and Quality of Life in Children and Adolescents With Migraine T2 - J Child Neurol TI - Assessment of Psychopathology and Quality of Life in Children and Adolescents With Migraine VL - 31 ID - 3466 ER - TY - JOUR AB - Recent studies indicate that adolescents often experience musculoskeletal pains in two or more body locations. However, previous studies have mainly focused on localized pains, and the determinants of multiple musculoskeletal pains in adolescents are not well known. The present study was set to evaluate the role of psychosocial, mechanical, and metabolic factors in adolescents' musculoskeletal pains in multiple locations. The study population consisted of the 1986 Northern Finland Birth Cohort; 15- to 16-year-old adolescents n = 6986), who responded to a mailed questionnaire in 2001. We assessed the associations of emotional and behavioral problems, physical activity, sitting time, sleeping time, overweight and smoking with musculoskeletal pains using multinomial logistic regression. Multiple pains were common, 23% of boys and 40% of girls reported feeling pain in at least three locations over the past 6 months. These pains were not only associated with anxious/depressed symptoms, withdrawn/depressed symptoms, somatic complaints, rule-breaking and aggressive behavior, social problems, thought and attention problems, but also with high physical activity level, long sitting time, short sleeping time and smoking, among both boys and girls. In addition, pain in three to four locations associated with overweight in girls. A high number of psychosocial, mechanical and metabolic factors associated strongly with multiple pains. In conclusion, multiple musculoskeletal pains were strongly associated with psychosocial complaints, but also with mechanical and metabolic factors. Reported musculoskeletal pains in multiple locations in adolescence may have both peripheral trauma, decreased regenerative ability) and central sensitivity) causes. (C) 2009 European Federation of International Association for the Study of Pain Chapters. Published by Elsevier Ltd. All rights reserved. AN - WOS:000277881000010 AU - Paananen, M. V. AU - Auvinen, J. P. AU - Taimela, S. P. AU - Tammelin, T. H. AU - Kantomaa, M. T. AU - Ebeling, H. E. AU - Taanila, A. M. AU - Zitting, P. J. AU - Karppinen, J. I. DA - Apr DO - 10.1016/j.ejpain.2009.06.003 IS - 4 N1 - Paananen, Markus V. Auvinen, Juha P. Taimela, Simo P. Tammelin, Tuija H. Kantomaa, Marko T. Ebeling, Hanna E. Taanila, Anja M. Zitting, Paavo J. Karppinen, Jaro I. Taimela, Simo/0000-0001-6755-2983; Kantomaa, Marko/0000-0002-5937-3456 1532-2149 PY - 2010 SN - 1090-3801 SP - 395-401 ST - Psychosocial, mechanical, and metabolic factors in adolescents' musculoskeletal pain in multiple locations: A cross-sectional study T2 - European Journal of Pain TI - Psychosocial, mechanical, and metabolic factors in adolescents' musculoskeletal pain in multiple locations: A cross-sectional study UR - ://WOS:000277881000010 VL - 14 ID - 2558 ER - TY - JOUR AB - Musculoskeletal pain in multiple sites is common already in adolescence, and may lead to subsequent musculoskeletal complaints in adulthood. We examined predictive factors for the persistence of multiple musculoskeletal pains in adolescence over a 2-year time span. A postal questionnaire was administered to a subsample of the Northern Finland Birth Cohort 1986 (n = 1773) when subjects were aged 16 and 18. The adjusted odds ratios (OR) and 95% confidence intervals (CI) for the possible risk factors of new-onset of multiple pains at 18 years and 2-year persistence of multiple pains were obtained using multinomial logistic regression. Multiple musculoskeletal pains were common; 43% of boys and 63% of girls at 16, and 61% of boys and 81% of girls at 18 reported pain in more than one site during the last 6 months. Moreover, multiple pains had a high persistence rate, as 75% of boys and 88% of girls with multiple pains at 16 reported multiple pains also at 18. In the multivariate analysis, emotional and behavioral problems (internalizing problems, OR 2.3; externalizing problems, OR 2.2), and high sitting time (OR 1.6) among boys, and internalizing problems (OR 3.7), high physical activity level (OR 1.6), short sleeping time (OR 1.7), and smoking (OR 1.9) among girls were predictive factors for the persistence of multiple pains. No statistically significant associations between the baseline variables and new-onset multiple pains were found. Multiple musculoskeletal pains appear to have a high tendency to persist in adolescence; both psychosocial factors and lifestyle factors contribute to this vulnerability. (C) 2010 European Federation of International Association for the Study of Pain Chapters. Published by Elsevier Ltd. All rights reserved. AN - WOS:000284061900008 AU - Paananen, M. V. AU - Taimela, S. P. AU - Auvinen, J. P. AU - Tammelin, T. H. AU - Kantomaa, M. T. AU - Ebeling, H. E. AU - Taanila, A. M. AU - Zitting, P. J. AU - Karppinen, J. I. DA - Nov DO - 10.1016/j.ejpain.2010.03.011 IS - 10 N1 - Paananen, Markus V. Taimela, Simo P. Auvinen, Juha P. Tammelin, Tuija H. Kantomaa, Marko T. Ebeling, Hanna E. Taanila, Anja M. Zitting, Paavo J. Karppinen, Jaro I. Taimela, Simo/0000-0001-6755-2983; Kantomaa, Marko/0000-0002-5937-3456 PY - 2010 SN - 1090-3801 SP - 1026-1032 ST - Risk factors for persistence of multiple musculoskeletal pains in adolescence: A 2-year follow-up study T2 - European Journal of Pain TI - Risk factors for persistence of multiple musculoskeletal pains in adolescence: A 2-year follow-up study UR - ://WOS:000284061900008 VL - 14 ID - 2532 ER - TY - JOUR AB - BACKGROUND: Patients with chronic exertional compartment syndrome who have failed nonoperative treatment are evaluated with pre-exertion and postexertion compartment pressure testing and may be treated with fasciotomy. Failure rates of up to 20% have been reported and may be related to factors such as age, sex, postexertion compartment pressures, compartment(s) released, and duration of symptoms. HYPOTHESIS: Higher preoperative postexertion compartment pressures are correlated with higher success and patient satisfaction rates after fasciotomy. STUDY DESIGN: Cohort study; Level of evidence, 3. METHODS: From 1999 to 2008, patients with clinical symptoms of chronic exertional compartment syndrome with failed nonoperative management underwent standardized pre-exertion and postexertion compartment pressure measurements. Patients were then offered continued nonoperative treatment or referral to an orthopaedic surgeon for compartment release. Patients with a minimum 2-year follow-up were given a telephone questionnaire describing their pretreatment and posttreatment conditions including quality and duration of symptoms, analog pain scale, symptomatic and functional responses to treatment, and satisfaction with treatment. Medical records and operative reports were reviewed. RESULTS: The mean follow-up period for the nonoperative treatment group (n = 27) was 5.6 years (range, 2.1-10.6) and for the operative group (n = 73) was 5.2 years (range, 2.0-11.3). The operative group had a higher success rate (81%) compared with the nonoperative group (41%) (P < .001), and the operative group had a higher patient satisfaction rate (81%) compared with the nonoperative group (56%) (P = .011). There was no significant correlation between compartment pressures and patient outcomes. Patients with combined anterior and lateral compartment releases had an increased failure rate compared with isolated anterior release (31% vs. 0%, respectively; P = .035). Surgical patients who were post-college had a lower satisfaction rate (66%) compared with high school (89%) and college patients (94%) (P = .017). CONCLUSION: High school and college patients (age <23 years) and isolated anterior compartment release (compared with anterior/lateral release) were factors associated with improved subjective function and satisfaction after fasciotomy. We recommend the avoidance of lateral release unless symptoms or postexertion compartment pressures are clearly indicative of lateral compartment involvement. AD - Hospital for Special Surgery, New York, New York, USA. jonathan.packer@yale.edu AN - 23371941 AU - Packer, J. D. AU - Day, M. S. AU - Nguyen, J. T. AU - Hobart, S. J. AU - Hannafin, J. A. AU - Metzl, J. D. DA - Feb DO - 10.1177/0363546512471330 DP - NLM ET - 2013/02/02 IS - 2 KW - Adolescent Adult Chronic Disease Compartment Syndromes/etiology/*surgery *Fasciotomy Female Humans Leg/*surgery Male Middle Aged Pain/*surgery Patient Satisfaction Running Treatment Outcome Young Adult LA - eng N1 - 1552-3365 Packer, Jonathan D Day, Michael S Nguyen, Joseph T Hobart, Sarah J Hannafin, Jo A Metzl, Jordan D Journal Article United States Am J Sports Med. 2013 Feb;41(2):430-6. doi: 10.1177/0363546512471330. PY - 2013 SN - 0363-5465 SP - 430-6 ST - Functional outcomes and patient satisfaction after fasciotomy for chronic exertional compartment syndrome T2 - Am J Sports Med TI - Functional outcomes and patient satisfaction after fasciotomy for chronic exertional compartment syndrome VL - 41 ID - 3545 ER - TY - JOUR AB - OBJECTIVES: Study objectives were to determine the impact of migraine and severe headache on employer burden, resource utilization, and workplace productivity before and after a migraine education program; estimate the associated costs in an employed sample; and evaluate whether a migraine management program can help manage costs. METHODS: Employees of three US companies were informed of a company-specific web site with information regarding the study as well as a validated migraine screening questionnaire. Employees who screened positive for migraine completed a baseline survey examining migraine frequency and severity, Migraine Disability Assessment (MIDAS) grade, medical resource utilization, and impact on workplace productivity. After the baseline survey, employees received three print packets and six e-mailed newsletters of migraine management educational materials. Six months after the last mailing, participants completed a follow-up survey. Participants were stratified by MIDAS grade and prevention needs status. Direct and indirect migraine-related costs were estimated and differences between baseline and follow-up survey results were analyzed. RESULTS: Indirect costs and measures of migraine impact improved after the educational program. Three-month indirect costs of migraine decreased 34.5% and total costs decreased 14.7% after the educational program. CONCLUSION: Migraine management programs, including screening questionnaires and educational initiatives, may potentially help reduce the employer cost burden due to improvements in their employees' disability associated with migraine headache. AD - Center for Health Economics, Epidemiology and Science Policy, United BioSource Corporation, Bethesda, MD, USA. AN - 19209043 AU - Page, M. J. AU - Paramore, L. C. AU - Doshi, D. AU - Rupnow, M. F. DA - Feb DO - 10.1097/JOM.0b013e318192bcd1 DP - NLM ET - 2009/02/12 IS - 2 KW - Absenteeism Adolescent Adult Efficiency Female *Health Care Costs Health Education/*organization & administration Health Services/*statistics & numerical data Humans Male Middle Aged Migraine Disorders/*economics/*prevention & control Occupational Health Services/*methods Program Evaluation Surveys and Questionnaires United States LA - eng N1 - 1536-5948 Page, Matthew J Paramore, L Clark Doshi, Dilesh Rupnow, Marcia F T Journal Article Research Support, Non-U.S. Gov't United States J Occup Environ Med. 2009 Feb;51(2):213-20. doi: 10.1097/JOM.0b013e318192bcd1. PY - 2009 SN - 1076-2752 SP - 213-20 ST - Evaluation of resource utilization and cost burden before and after an employer-based migraine education program T2 - J Occup Environ Med TI - Evaluation of resource utilization and cost burden before and after an employer-based migraine education program VL - 51 ID - 3252 ER - TY - JOUR AB - Hereditary angioedema is a rare disease. In case of laryngeal edema or chronic abdominal pains, diagnosis is difficult in childhood because numerous differential diagnoses possibilities are to be considered. The diagnosis of hereditary angioedema with normal CI lnh (type III) is also a challenge because it is based only on clinical features. Important school absenteeism can be due to recurrent abdominal attacks. Early diagnosis, specific management, and therapeutic education are necessary for improvement of quality of life. Actually, subcutaneous treatment is not yet available for children. Studies are going on. In the meantime, C Inh concentrate intravenous administration must be available for children quickly and safely. AN - WOS:000350008000015 AU - Pagnier, A. DA - Jan DO - 10.1016/j.lpm.2014.07.018 IS - 1 N1 - Pagnier, Anne 2213-0276 PY - 2015 SN - 0755-4982 SP - 89-95 ST - Hereditary angioederna in childhood. Diagnosis and therapeutic challenges T2 - Presse Medicale TI - Hereditary angioederna in childhood. Diagnosis and therapeutic challenges UR - ://WOS:000350008000015 VL - 44 ID - 2260 ER - TY - JOUR AB - This report investigates associations between prevalence of functional disturbances of the masticatory system and speech disorders. The subjects were 157 children referred for speech therapy to the hospital and a control group all 130 first-graders at two elementary schools, mean age 7 years 6 months. During clinical examinations, signs and symptoms of TMJ dysfunction were recorded by the same dentist. Articulatory speech disorders were diagnosed by the same phoniatrician using the Remes Articulatory Test (Remes, 1975) for the Finnish language. The results showed that in the hospital referral group the mean value for maximal opening was smaller while laterotrusion movements and maximal protrusion of the mandible were larger than in the control group. The study group also more often had CM disorders and occlusal interferences than children of the first grade sample. In the present data, a higher frequency of subjective symptoms and several clinical signs of CMD were related to certain articulatory speech disorders. Risk of having too anteriorly-produced sounds, mainly 's'-sounds, decreased with advancing age in 6-8-year-old children. In conclusion, expression of both craniomandibular disorder and disorders in speech sound production seem to a considerable extent to reflect immaturity of fine motor control of the orofacial muscles in 6-8-year-old children. AD - Department of Orthodontics, Faculty of Dentistry, University of Kuopio, Finland. AN - 1748185 AU - Pahkala, R. AU - Laine, T. AU - Närhi, M. AU - Ettala-Ylitalo, U. M. DA - Oct DO - 10.1093/ejo/13.5.378 DP - NLM ET - 1991/10/01 IS - 5 KW - Articulation Disorders/*complications Child Dental Occlusion, Traumatic/complications/physiopathology Female Finland Humans Male Malocclusion/complications/physiopathology Mandible/physiopathology Phonetics Range of Motion, Articular/physiology Regression Analysis Sex Factors Sound Temporomandibular Joint/physiopathology Temporomandibular Joint Dysfunction Syndrome/*complications/diagnosis/physiopathology LA - eng N1 - Pahkala, R Laine, T Närhi, M Ettala-Ylitalo, U M Journal Article Research Support, Non-U.S. Gov't England Eur J Orthod. 1991 Oct;13(5):378-85. doi: 10.1093/ejo/13.5.378. PY - 1991 SN - 0141-5387 (Print) 0141-5387 SP - 378-85 ST - Relationship between craniomandibular dysfunction and pattern of speech sound production in a series of first-graders T2 - Eur J Orthod TI - Relationship between craniomandibular dysfunction and pattern of speech sound production in a series of first-graders VL - 13 ID - 3566 ER - TY - JOUR AB - Tonsillectomy is a very painful procedure. Pain may be severe, and patients are often unable to perform in school or eat regular food for a number of days after the surgery. The aim of this study was to compare the quality of life after undergoing two different surgical techniques of tonsillectomy, harmonic scalpel and classic tonsillectomy with bipolar cauterization. Prospective randomized double-blind, clinical trial study conducted in the ENT Department, Dr. Josip BeneviA double dagger General Hospital, Slavonski Brod, Croatia. Data were collected, according to the type of operation, on pain persistence and intensity and returning to normal eating with tonsillectomy patients during the first seven postoperative days. Group A consisted of 50 children submitted to classic tonsillectomy with bipolar cauterization, while group B included 50 children operated on using the harmonic scalpel. Data on pain intensity were obtained using pain measuring scales adjusted to children's age (Faces scales, visual analog scale). The first day of normal oral food intake was recorded. The analysis of variance revealed that the grade of pain significantly differs by a surgical technique employed, and that it significantly varied over the first seven postoperative days. The pain was more severe after undergoing the harmonic scalpel technique and children started to eat later compared with the classic tonsillectomy. The classic tonsillectomy method with bipolar cauterization is the method of choice due to lower postoperative pain levels and sooner normal eating. The quality of life is better after undergoing the classic tonsillectomy method. AN - WOS:000324549800005 AU - Pajic-Penavic, I. AU - Danic, D. AU - Mrzljak-Vucinic, N. AU - Matic, I. AU - Vukovic-Arar, Z. AU - Dikanovic, M. DA - Sep DO - 10.1007/s00508-013-0411-6 IS - 17-18 N1 - Pajic-Penavic, Ivana Danic, Davorin Mrzljak-Vucinic, Natalija Matic, Ivo Vukovic-Arar, Zeljka Dikanovic, Marinko PY - 2013 SN - 0043-5325 SP - 524-528 ST - Postoperative quality of life after two different methods of tonsillectomy T2 - Wiener Klinische Wochenschrift TI - Postoperative quality of life after two different methods of tonsillectomy UR - ://WOS:000324549800005 VL - 125 ID - 2352 ER - TY - JOUR AB - Objective To provide an evidence-based review of measures of health-related quality of life (HRQOL) and functional impairment, with a specific focus on their use in the field of pediatric psychology. Methods As part of a larger survey of pediatric psychologists from the Society of Pediatric Psychology e-mail listserv (American Psychological Association, APA, Division 54), 16 measures were selected for this psychometric review. Measures that qualified for the review fell into one of the following three categories: (a) generic HRQOL scales, (b) disease-specific quality of life scales, and (c) functional impairment rating scales. Results Psychometric characteristics (i.e., three types of reliability, two types of validity) were strong for the majority of measures reviewed, with 12 of the 16 measures meeting well-established evidence-based assessment criteria. Strengths and weaknesses of existing measures were noted. Conclusions Recommendations for future work in this area of assessment are presented, including suggestions that further validation and exploration of measure properties such as factor analysis and changes in HRQOL over time be conducted. AN - WOS:000259329400008 AU - Palermo, T. M. AU - Long, A. C. AU - Lewandowski, A. S. AU - Drotar, D. AU - Quittner, A. L. AU - Walker, L. S. DA - Oct DO - 10.1093/jpepsy/jsn038 IS - 9 N1 - Palermo, Tonya M. Long, Anna C. Lewandowski, Amy S. Drotar, Dennis Quittner, Alexandra L. Walker, Lynn S. 1465-735x PY - 2008 SN - 0146-8693 SP - 983-996 ST - Evidence-based assessment of health-related quality of life and functional impairment in pediatric psychology T2 - Journal of Pediatric Psychology TI - Evidence-based assessment of health-related quality of life and functional impairment in pediatric psychology UR - ://WOS:000259329400008 VL - 33 ID - 2635 ER - TY - JOUR AB - The aim of this study was to examine the relationship between individual/family and neighborhood socioeconomic distress, pain, and functional outcomes in children with sickle cell disease (SCD). We hypothesized that both individual economic distress as well as residence in neighborhoods of severe economic distress would predict children's level of pain-related functional disability and health-related quality of life (HRQOL). Participants (mean age, 12.14 years; 57% male, n = 56) were recruited from an outpatient hematology clinic at a Midwestern tertiary referral hospital. Questionnaires assessing pain, depression, functional disability, and HRQOL were completed by children and their caregivers. Individual socioeconomic data including parental education and family income were reported by caregivers. Neighborhood socioeconomic distress was identified using publicly available census tract data and was based on neighborhood poverty, female head of household, male unemployment, and high school dropout levels. Multivariate regression analyses revealed that individual/family socioeconomic distress was a significant predictor of children's functional disability and physical and psychosocial HRQOL. Neighborhood socioeconomic distress emerged as a significant independent predictor of physical HRQOL only, where living in a distressed neighborhood predicted diminished physical HRQOL. Findings suggest that individual socioeconomic status and neighborhood economic distress play similar but independent roles in predicting children's functional outcomes related to SCD pain. PERSPECTIVE: Little is known about the influence of either individual/family or neighborhood socioeconomic factors on pain and functioning in children with SCD. Our findings suggest that socioeconomic distress defined at both the individual level and at the neighborhood/community level are significant independent predictors of pain-related disability and HRQOL in children with SCD. AD - Department of Anesthesiology and Peri-Operative Medicine, Oregon Health and Science University, Portland, Oregon 97239, USA. palermot@ohsu.edu AN - 18550443 AU - Palermo, T. M. AU - Riley, C. A. AU - Mitchell, B. A. C2 - PMC2629395 C6 - NIHMS69185 DA - Sep DO - 10.1016/j.jpain.2008.04.002 DP - NLM ET - 2008/06/14 IS - 9 KW - Activities of Daily Living/*psychology Adolescent Anemia, Sickle Cell/complications/*psychology Caregivers/psychology Child Family/psychology Female Health Status Humans Male Pain/etiology/*psychology Pain Measurement/methods Poverty/psychology Quality of Life/*psychology Regression Analysis Residence Characteristics/statistics & numerical data Sickness Impact Profile Socioeconomic Factors Stress, Psychological/psychology Surveys and Questionnaires LA - eng N1 - 1528-8447 Palermo, Tonya M Riley, Craig A Mitchell, Brian A K23 MH001837/MH/NIMH NIH HHS/United States K23 MH001837-06/MH/NIMH NIH HHS/United States K23MH01837/MH/NIMH NIH HHS/United States Journal Article Research Support, N.I.H., Extramural J Pain. 2008 Sep;9(9):833-40. doi: 10.1016/j.jpain.2008.04.002. Epub 2008 Jun 12. PY - 2008 SN - 1526-5900 (Print) 1526-5900 SP - 833-40 ST - Daily functioning and quality of life in children with sickle cell disease pain: relationship with family and neighborhood socioeconomic distress T2 - J Pain TI - Daily functioning and quality of life in children with sickle cell disease pain: relationship with family and neighborhood socioeconomic distress VL - 9 ID - 3935 ER - TY - JOUR AB - Recurrent pain in childhood are common and frequently impact children's everyday functioning. However, there are currently limited tools available to measure the impact of recurrent pain on children's daily activities, in particular, that can be used to identify appropriate targets for intervention and measure response to such interventions. The purpose of this study was to develop and validate a new measure, the Child Activity Limitations Interview (CALI), to improve the assessment of functional impairment due to recurrent pain in school-age children and adolescents, and to compare this measure to the Functional Disability Inventory. Participants included 189 children, aged 8-16 years (M=12.4, SD 2.5), 60% female, 40% minority, who were part of a longitudinal study of recurrent pain in children with headaches, juvenile idiopathic arthritis, and sickle cell disease. Measures of socio-demographics, pain, anxiety and depression, and functional disability were completed. A subset of participants (47%) were re-administered the CALI 1 month later and completed prospective ratings of pain and activity limitations using the CALI in daily diaries. Internal consistency of the CALI was excellent (alpha=0.88, child version; alpha=0.95, parent version). One-month test-retest reliability (r = 0.33, child report) and cross-informant reliability (r = 0.43) were moderate. Results demonstrate support for face, construct, and concurrent validity as well as responsiveness to pain symptom fluctuation. Findings demonstrate that the CALI is a promising measure for assessing and monitoring subjective report of functional impairment in school-age children and adolescents with recurrent and chronic pain. AU - Palermo, Tonya M. AU - Witherspoon, Dawn AU - Valenzuela, Duaré AU - Drotar, Dennis D. DA - 2004/06// DO - 10.1016/j.pain.2004.02.023 DP - PubMed IS - 3 J2 - Pain KW - Activities of Daily Living Adolescent Anxiety Child Comorbidity Depression Disability Evaluation Female Humans Longitudinal Studies Male Observer Variation Pain Pain Measurement Predictive Value of Tests Prospective Studies Recurrence Reproducibility of Results Surveys and Questionnaires LA - eng PY - 2004 SN - 0304-3959 SP - 461-470 ST - Development and validation of the Child Activity Limitations Interview T2 - Pain TI - Development and validation of the Child Activity Limitations Interview: a measure of pain-related functional impairment in school-age children and adolescents UR - http://www.ncbi.nlm.nih.gov/pubmed/15157707 VL - 109 ID - 128 ER - TY - JOUR AB - Objective The current study explored whether the chances of having migraine are influenced by a youth's friendship with a migraineur. Methods The study was centered on a community-based non-referral cohort of eighth graders from two middle schools in Taiwan. Among the 642 recruited adolescent students, 610 (95%) (mean age 14.1 years, male ratio 51.2%) nominated three good friends and completed a validated headache questionnaire for migraine diagnosis at the follow-up survey 1 year later. To explore social influences on incident migraine, we used longitudinal statistical models to examine whether the development of migraine in one adolescent during the 1-year observational period was associated with that in his/her friends. Results Overall, 1700 social ties were established in the social network based on the reported lists of good friends. Randomization test for the homophily effect demonstrated that the students with migraine tended to cluster together in the social network even when those with incident migraine were also considered (p = 0.003). Besides, when friendship choices were mutual, the relative risk of an adolescent becoming a migraineur was 3.26 (95% CI: 1.25-8.47,p = 0.015) if his/her friend became a migraineur (induction) during the 1-year observational period. Conclusion To the best of our knowledge, this is the first study to demonstrate that migraine may spread through social networks in young adolescents. Both homophily and induction effects are possibly contributory. AN - WOS:000546611600001 AU - Pan, Y. J. AU - Chen, Y. C. AU - Lu, S. R. AU - Juang, K. D. AU - Chen, S. P. AU - Wang, Y. F. AU - Fuh, J. L. AU - Wang, S. J. C7 - 0333102420940700 DA - Oct DO - 10.1177/0333102420940700 IS - 12 N1 - Pan, Yi-Ju Chen, Yu-Chun Lu, Shiang-Ru Juang, Kai-Dih Chen, Shih-Pin Wang, Yen-Feng Fuh, Jong-Ling Wang, Shuu-Jiun Chen, Yu Chun/K-6635-2019 Chen, Shih-Pin/0000-0003-3492-9902 1468-2982 PY - 2020 SN - 0333-1024 SP - 1321-1330 ST - The influence of friendship on migraine in young adolescents: A social network analysis T2 - Cephalalgia TI - The influence of friendship on migraine in young adolescents: A social network analysis UR - ://WOS:000546611600001 VL - 40 ID - 1810 ER - TY - JOUR AB - Objective: Evidence regarding the role of risk factors in the longitudinal course of suicidal ideation among young adolescents is lacking. We aimed to assess the effects of a range of risk factors, including obesity, academic performance, child-parent relationship, physical maltreatment, and depressive symptoms, on the development of suicidal ideation in young adolescents. Methods: A school cohort of seventh and eighth graders was followed for 1year and differences in the risk factors distributions were examined between depressed and non-depressed adolescents. We further examined risk factors for newly developed suicidal ideation and persistent suicidal ideation in the groups of adolescents based on the presence of suicidal ideation at baseline. Results: A total of 1710 young adolescents were recruited, among whom 8.2% were categorised as having clinically significant depression. For depressed adolescents, being obese was associated with a three-fold increased risk of having suicidal ideation. For non-depressed adolescents, physical maltreatment, a feeling of not being cared about and sub-threshold depressive symptoms were the risk factors. The latter two remained robust in predicting newly developed suicidal ideation. Conclusion: The current study may shed light on the differential strategies to address suicidal thoughts in depressed and non-depressed adolescents. We emphasise the importance of recognition and management of sub-threshold depressive symptoms and the relevance of obesity, physical maltreatment and a feeling of not being cared about to suicide prevention programmes in early adolescence. AN - WOS:000408226400012 AU - Pan, Y. J. AU - Juang, K. D. AU - Lu, S. R. AU - Chen, S. P. AU - Wang, Y. F. AU - Fuh, J. L. AU - Wang, S. J. DA - Sep DO - 10.1177/0004867417717795 IS - 9 N1 - Pan, Yi-Ju Juang, Kai-Dih Lu, Shiang-Ru Chen, Shih-Pin Wang, Yen-Feng Fuh, Jong-Ling Wang, Shuu-Jiun 1440-1614 PY - 2017 SN - 0004-8674 SP - 930-937 ST - Longitudinal risk factors for suicidal thoughts in depressed and non-depressed young adolescents T2 - Australian and New Zealand Journal of Psychiatry TI - Longitudinal risk factors for suicidal thoughts in depressed and non-depressed young adolescents UR - ://WOS:000408226400012 VL - 51 ID - 2075 ER - TY - JOUR AB - Background: Headache is a common health problem among health professional students which may negatively affect their academic performance and quality of life. The study aimed to determine the prevalence, pattern, associated psychosocial factors and treatment seeking behavior regarding headache among the students of health profession. Methods: The cross sectional study was undertaken during April-September 2016 involving 339 students studying medical, dental and nursing health sciences in KIIT University, Bhubaneswar, India. A semi-structured questionnaire was used to collect all relevant information. Numeric Pain Rating Scale (NPRS) and Headache Attributed Lost Time (HALT) index were used to assess subjective perception regarding intensity of pain over the previous 24 h and disability burden over the last 3 months respectively. Results: The one year prevalence of headache was 73.1%, of which migraine and tension type headache were 33.3% and 19.2% respectively. In majority (93.2%) of the students, the intensity of pain was mild to moderate. More than one third (37.1%) of students reported that headache was affecting their family, social and leisure activities with moderate-severe impact indicating high need of medical care. Logistic regression analysis revealed that female gender (adjusted OR: 2.67), problem in falling asleep (adjusted OR: 2.86), problem in staying asleep (adjusted OR: 11.11), soft drink consumption (adjusted OR: 2.22) and self dissatisfaction with own health (adjusted OR: 1.89) were significantly associated with headache. Conclusion: High prevalence of headache among the students of health profession necessitates designing of appropriate strategies to improve the quality of life in this population. AN - WOS:000533485300008 AU - Panigrahi, A. AU - Behera, B. K. AU - Sarma, N. N. DA - Jun DO - 10.1016/j.cegh.2019.09.004 IS - 2 N1 - Panigrahi, Ansuman Behera, Basanta Kumar Sarma, Nibir Nath Panigrahi, Ansuman/K-4883-2018 2213-3984 PY - 2020 SN - 2452-0918 SP - 365-370 ST - Prevalence, pattern, and associated psychosocial factors of headache among undergraduate students of health profession T2 - Clinical Epidemiology and Global Health TI - Prevalence, pattern, and associated psychosocial factors of headache among undergraduate students of health profession UR - ://WOS:000533485300008 VL - 8 ID - 1823 ER - TY - JOUR AB - The aim of this paper is to review the main topics about the management of paediatric tension-type headache. A Medline search was undertaken of all reports and reviews published between 1990 and 2010 using MeSH search terms 'tension-type headache (TTH), 'treatment' and 'children'. TTH is a very common disorder in childhood and adolescents. In many cases, the frequency and intensity of episodes may be likely to interfere with school and social activities. For this reason, a correct diagnosis and appropriate management of TTH are essential. A detailed history and proper examination, as well as a headache diary, are essential for this purpose and help to distinguish secondary causes of headache. Lacking are studies to test the efficacy and safety of pharmacological treatment in children, and a few well-tested drugs are available for this purpose. To date, relaxation techniques and biofeedback are therefore best placed as the first-line therapies. CONCLUSION: A thorough evaluation of headache in paediatric age is necessary to make a correct diagnosis and start the appropriate treatment. In particular, an appropriate management requires an individually tailored strategy which should include both pharmacological and nonpharmacological therapies. New treatment options for elderly patients with headache including acute, prophylactic and interventional techniques are needed. AD - Child Neurology, Headache Paediatric Center, Paediatric Sleep Centre, Chair of Pediatrics, II Faculty of Medicine, Sapienza University, c/o Sant'Andrea Hospital, Rome, Italy. pasquale.parisi@uniroma1.it AN - 21143645 AU - Parisi, P. AU - Papetti, L. AU - Spalice, A. AU - Nicita, F. AU - Ursitti, F. AU - Villa, M. P. DA - Apr DO - 10.1111/j.1651-2227.2010.02115.x DP - NLM ET - 2010/12/15 IS - 4 KW - Adolescent Biofeedback, Psychology Child Humans Relaxation Therapy Tension-Type Headache/diagnosis/*therapy LA - eng N1 - 1651-2227 Parisi, Pasquale Papetti, Laura Spalice, Alberto Nicita, Francesco Ursitti, Fabiana Villa, Maria Pia Journal Article Review Norway Acta Paediatr. 2011 Apr;100(4):491-5. doi: 10.1111/j.1651-2227.2010.02115.x. Epub 2011 Jan 12. PY - 2011 SN - 0803-5253 SP - 491-5 ST - Tension-type headache in paediatric age T2 - Acta Paediatr TI - Tension-type headache in paediatric age VL - 100 ID - 3034 ER - TY - JOUR AB - Objective The aim of this study was to: (1) establish the typical experience of menstruation for senior high school girls and (2) determine how many experience considerable menstrual disturbance that could require further investigation and management of underlying pathology. Design Cross-sectional study. Setting Senior High Schools in the Australian Capital Territory (ACT), Australia. Population A total of 1051 girls aged between 15 and 19 years. Methods Data based on a quantitative survey. Main outcome measures Self-reports of menstrual bleeding patterns, typical and atypical symptoms and morbidities. Results Typical menstruation in adolescence includes pain (93%), cramping (71%), premenstrual symptoms (96%) and mood disturbance (73%). Highly significant associations were found between increasing severity of menstrual pain, number of menstrual-related symptoms, interference with life activities and school absence. These associations indicate that approximately 25% of the sample had marked menstrual disturbance: 21% experienced severe pain; 26% school absence; 26% suffering five or more symptoms; >= 24% reporting moderate to high interference with four out of nine life activities. Approximately 10% reported atypical symptoms associated with menstruation. Diagnosis of menstrual pathology in the sample was low, even though 33% had seen a GP and 9% had been referred to a specialist. Conclusions Menstrual pain and symptoms are common in teenagers. Girls indicating moderate to severe pain in association with a high number of menstrual symptoms, school absence and interference with life activities should be effectively managed to minimise menstrual morbidity. Those girls who do not respond to medical management should be considered for further investigation for possible underlying pathology, such as endometriosis. AN - WOS:000272568000011 AU - Parker, M. A. AU - Sneddon, A. E. AU - Arbon, P. DA - Jan DO - 10.1111/j.1471-0528.2009.02407.x IS - 2 N1 - Parker, M. A. Sneddon, A. E. Arbon, P. Arbon, Paul/0000-0002-5914-3300; Parker, Melissa A/0000-0002-4213-7166 1471-0528 PY - 2010 SN - 1470-0328 SP - 185-192 ST - The menstrual disorder of teenagers (MDOT) study: determining typical menstrual patterns and menstrual disturbance in a large population-based study of Australian teenagers T2 - Bjog-an International Journal of Obstetrics and Gynaecology TI - The menstrual disorder of teenagers (MDOT) study: determining typical menstrual patterns and menstrual disturbance in a large population-based study of Australian teenagers UR - ://WOS:000272568000011 VL - 117 ID - 2570 ER - TY - JOUR AB - BACKGROUND: Pain is one of the most commonly reported symptoms in people living with HIV/AIDS, whether or not they are receiving anti-retroviral therapy. A recent systematic review identified a paucity of studies exploring pain in women in low and middle income countries. The prevalence and characteristics of pain in women living with HIV/AIDS may differ from that of men as many chronic pain conditions are more prevalent in women. The aims of this study were to establish pain prevalence, characteristics and management in amaXhosa women living with HIV/AIDS. In addition, we aimed to identify whether there were associations between pain in this population and the psychosocial factors of employment, education, self-efficacy, depression, post-traumatic stress disorder, health related quality of life and childhood trauma. METHODS: A cross-sectional study of 229 women who had undergone HIV testing and were registered patients at a community health centre was conducted. Data were collected by interview with a demographic questionnaire, the Brief Pain Inventory-Xhosa, Childhood Trauma Questionnaire-Xhosa, Harvard Trauma Questionnaire-Xhosa for PTSD, Self-Efficacy for Managing Chronic Disease 6-Item Scale-Xhosa; the EQ-5D health related quality of life instrument, and the Beck Depression Inventory. RESULTS: 170 of the women had pain, a prevalence rate of 74.24% (95%CI 68.2 - 79.47%). The women reported significant pain with pain severity of 5.06 ± 1.57 and pain interference of 6.39 ± 1.96 out of 10. Only two women were receiving adequate pain management according to the pain management index. Participants reported a mean of 2.42 ± 1.21 different anatomical sites of pain. There were more unemployed participants in the group with pain and they had significantly fewer years of schooling. Those with pain had lower self-efficacy; health related quality of life and increased depression and PTSD symptom severity. CONCLUSION: This study highlights that pain is a common problem for amaXhosa women living with HIV/AIDS. These data emphasise the need to prioritise pain assessment and management in amaXhosa women living with HIV/AIDS. Routinely assessing for the presence of pain in women with HIV/AIDS has the potential to improve pain management and minimise the impact of pain on function. AD - Department of Health & Rehabilitation Sciences, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory, 7925, Cape Town, South Africa. romy.parker@uct.ac.za. Department of Health & Rehabilitation Sciences, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory, 7925, Cape Town, South Africa. Department of Psychiatry & Mental Health, MRC Unit on Anxiety & Stress Disorders, Groote Schuur Hospital, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa. AN - 28407737 AU - Parker, R. AU - Jelsma, J. AU - Stein, D. J. C2 - PMC5390474 DA - Apr 13 DO - 10.1186/s12905-017-0388-9 DP - NLM ET - 2017/04/15 IS - 1 KW - Adolescent Adult Ambulatory Care Facilities/organization & administration Cross-Sectional Studies Female HIV Infections/*complications/psychology HIV-1/pathogenicity Humans Outpatients/*psychology Pain/*epidemiology/etiology Pain Management/*methods Psychometrics/instrumentation/methods South Africa/epidemiology Surveys and Questionnaires *hiv/aids *Pain *Prevalence LA - eng N1 - 1472-6874 Parker, Romy Orcid: 0000-0003-4823-2487 Jelsma, Jennifer Stein, Dan J Journal Article BMC Womens Health. 2017 Apr 13;17(1):31. doi: 10.1186/s12905-017-0388-9. PY - 2017 SN - 1472-6874 SP - 31 ST - Pain in amaXhosa women living with HIV/AIDS: a cross-sectional study of ambulant outpatients T2 - BMC Womens Health TI - Pain in amaXhosa women living with HIV/AIDS: a cross-sectional study of ambulant outpatients VL - 17 ID - 3722 ER - TY - JOUR AB - Historically, health-related quality of life (HRQL) assessment in pediatrics, including the few validated instruments in pediatric oncology, has been based on proxy reporting, relying primarily on parental assessment. Children have been deemed incapable of providing consistent and reliable information about their level of functioning or state of well-being. Previous studies have been hampered by either limited or poor correlation among the proxy reporters, i.e., teachers, parents and physicians, and in comparisons to disease severity. Simply stated, proxy reporters have greater agreement about what the child can do vs. what the child thinks or feels. Comparisons among proxy reporters have been hindered also by a lack of parallel content in the instruments used, which may result in poorly congruent assessments simply because the instruments measure different constructs. In addition to the measurement issues, the emotional milieu of the parent, particularly the mother, has been shown to influence assessments of the child's functioning. Maternal distress, marital adjustment and health locus of control all co-vary with reports of the child's behavior. What, then, is the proxy reporter telling us about the child? We conducted a cross-sectional study of school-aged pediatric bone marrow transplant (BMT) patients at our institution to evaluate children's self-reported HRQL and functional status, We formally tested the Child Health Rating Inventories (CHRIs), a recently developed generic hearth-status measure, with its companion measure, the Disease Impairment Inventories-Bone Marrow Transplant (DSII-BMT). Separate questionnaires were administered to patients, parents and physicians at a scheduled outpatient visit after BMT. The questionnaires were designed to have parallel content. All responses were confidential, The psychometric properties of the CHRIs and DSII-BMT are reported elsewhere. In brief, the responses of all raters were reliable, based on measurements of internal consistency. The children's self-reported health status was correlated significantly with the physicians' disease severity rating (DSR) across all generic and disease-specific domains. In contrast, parental reports of child health status were not correlated significantly with the DSR for disease-specific problems or the child's pain. Parental ratings deviated most from the children's ratings within the dimensions of mental health and quality of life (p < 0.001), For the entire sample, parental ratings were significantly lower than the children's ratings. Within the subgroup "early after transplant (<6 months)", parental ratings were significantly lower than the children's self-reports in all categories. in the subgroup "> 12 months after transplant", with the exception of mental health and quality of life, parental scores were the same as or higher than the children's ratings. Our results confirm previous studies that the parental reporting of children's health status is a complex construct and that valuable information can be elicited directly from the children. Further research is needed to substantiate these findings, particularly in longitudinal applications with adequate sample sizes. Int. J. Cancer Suppl. 12:46-51, 1999, (C) 1999 Wiley-Liss, Inc. AN - WOS:000084615500009 AU - Parsons, S. K. AU - Barlow, S. E. AU - Levy, S. L. AU - Supran, S. E. AU - Kaplan, S. H. N1 - Parsons, SK Barlow, SE Levy, SL Supran, SE Kaplan, SH International Workshop on Assessing Health-Related Quality of Life in Children with Cancer Jun 21-24, 1998 Niagara on the lake, canada 12 PY - 1999 SN - 0020-7136 SP - 46-51 ST - Health-related quality of life in pediatric bone marrow transplant survivors: According to whom? T2 - International Journal of Cancer TI - Health-related quality of life in pediatric bone marrow transplant survivors: According to whom? UR - ://WOS:000084615500009 ID - 2885 ER - TY - JOUR AB - Background: The prevalence of chronic pain is about 30% in children and adolescents which suffer from severe emotional distress. The aim of this observational study is to investigate cognitive, emotional and behavioral consequences of benign chronic pain in children and adolescents suffering of reumathologic diseases. Materials and Methods: A total of 49 participants, chronic pain participants (CPPs) and controls (CGPs), affected by rheumatic diseases, were enrolled. Assessment included collection of sociodemographic data, pain characteristics, and administration of Visual Analog Scale (VAS), Depression Inventory for Children and Adolescents (CDI), Conners' Parent Rating Scales-Revised (CPRS-R), Child Behavior Checklist (CBCL), and Screen for Child Anxiety-Related Disorders (SCARED). For the statistical analysis, Student's t-test for independent samples and Pearson's correlation were used. The significance value was set at p less than .05. Results: A significant difference of mean scores of CBCL items and of CPRS items between the two groups was found. In CPPs, a significant correlation between VAS and mean scores of several CBCL items and between VAS and mean scores of several CPRS items was found. Conclusion: Chronic pain is a real syndrome in which an interdisciplinary treatment should be applied, considering the psychopathological risk, especially in developmental age. AN - WOS:000474899900003 AU - Pascali, M. AU - Matera, E. AU - Craig, F. AU - Torre, F. L. AU - Giordano, P. AU - Margari, F. AU - Zagaria, G. AU - Margari, M. AU - Margari, L. DA - Jul DO - 10.1177/1359104518805800 IS - 3 N1 - Pascali, Maria Matera, Emilia Craig, Francesco Torre, Francesco La Giordano, Paola Margari, Francesco Zagaria, Giuseppina Margari, Mariella Margari, Lucia Craig, Francesco/ABG-2873-2020; Margari, Lucia/AAK-4375-2021 Craig, Francesco/0000-0003-3454-6653; Margari, Lucia/0000-0002-9203-3373 1461-7021 PY - 2019 SN - 1359-1045 SP - 433-445 ST - Cognitive, emotional, and behavioral profile in children and adolescents with chronic pain associated with rheumatic diseases: A case-control study T2 - Clinical Child Psychology and Psychiatry TI - Cognitive, emotional, and behavioral profile in children and adolescents with chronic pain associated with rheumatic diseases: A case-control study UR - ://WOS:000474899900003 VL - 24 ID - 1901 ER - TY - JOUR AB - OBJECTIVE: To describe the effectiveness of engaging patient partners as "citizen scientists" in the research process to boost patient centered outcomes research in underrepresented populations. METHODS: Translational Advisory Boards in South Texas have effectively collaborated with University researchers to develop community-based patient centered research. Here we describe innovative approaches in research to engage patients and offer practical methods to enhance partnerships between patients and researchers to facilitate patient engagement. RESULTS: Three health issues identified by the TABs were diabetes, obesity and teen pregnancy Examples of other community inspired research topics include air and water quality, methicillin-resistant staphylococcus aureus, intimate partner violence, chronic pain, and human papilloma virus and hepatitis C vaccinations. CONCLUSION: Patient engagement of underrepresented populations is inverse to the vast disparities they experience. In order to adequately address our nation's deficits in providing equitable healthcare, we must fully integrate disparate partners into the research process. By engaging community champions, academic health centers can fully integrate meaningful interventions on topics of interest to the catchment area in which they serve. PRACTICE IMPLICATIONS: These lessons can be used in developing local and regional collaborations across the country to boost active participation of patient stakeholder in PCOR to reduce healthcare disparities and improve our healthcare systems. AD - Department of Health Restoration and Care Systems Management, School of Nursing, University of Texas Health Science Center at San Antonio, San Antonio, USA; Cancer Therapy and Research Center, University of Texas Health Science Center at San Antonio, San Antonio, USA. Electronic address: pateld7@uthscsa.edu. South Central Area Health Education Center, Center for South Texas Programs University of Texas Health Science Center at San Antonio, San Antonio, USA. Winter Garden Texas Translational Advisory Board, TX, USA. Frio County Texas Translational Advisory Board, USA. Department of Health Restoration and Care Systems Management, School of Nursing, University of Texas Health Science Center at San Antonio, San Antonio, USA. AN - 27432015 AU - Patel, D. I. AU - Winkler, P. AU - Botello, J. AU - Villarreal, J. AU - Puga, F. DA - Dec DO - 10.1016/j.pec.2016.07.013 DP - NLM ET - 2016/07/20 IS - 12 KW - Community-Based Participatory Research/*methods Community-Institutional Relations Cooperative Behavior *Health Services Accessibility Health Status Disparities *Healthcare Disparities Humans *Patient Outcome Assessment *Patient Participation Texas Translational Medical Research/*organization & administration Universities *Community engagement *Patient centered outcomes research *Patient engagement *Stakeholder engagement *Translational Advisory Boards LA - eng N1 - 1873-5134 Patel, Darpan I Winkler, Paula Botello, Jorge Villarreal, Jocelin Puga, Frank UL1 TR001120/TR/NCATS NIH HHS/United States Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Ireland Patient Educ Couns. 2016 Dec;99(12):2087-2090. doi: 10.1016/j.pec.2016.07.013. Epub 2016 Jul 5. PY - 2016 SN - 0738-3991 SP - 2087-2090 ST - The citizen scientist: Community-academic partnerships through Translational Advisory Boards T2 - Patient Educ Couns TI - The citizen scientist: Community-academic partnerships through Translational Advisory Boards VL - 99 ID - 4207 ER - TY - JOUR AB - The growing child with a tethered spinal cord experiences serious neurological deficits as a result of traction on the conus medullaris. Children with tethered cords most commonly present with pain in the lower back, with motor or sensory loss in the lower limbs, with bowel or bladder dysfunction, or with scoliosis. Often, the neurological basis of these symptoms is overlooked. Surgical release of tethering arrests neurological deterioration. Without surgical intervention symptoms will progressively worsen and may become irreversible. Preoperatively the nurse must prepare the child and his family for neurological investigations and for surgery. Postoperatively the nurse must be skilled in assessing spinal cord function, providing pain management, and assisting in ambulation. This presentation will review the pathophysiology of the tethered spinal cord, the preparation of the school-aged child for surgery, and the postoperative nursing care of the pediatric laminectomy patient. AN - 2688738 AU - Patterson, P. DA - Dec DP - NLM ET - 1989/12/01 IS - 2 KW - Child Humans Pediatric Nursing Postoperative Care Preoperative Care Spinal Cord/*abnormalities/surgery LA - eng N1 - Patterson, P Journal Article Review Canada Axone. 1989 Dec;11(2):38-40. PY - 1989 SN - 0834-7824 (Print) 0834-7824 SP - 38-40 ST - The tethered spinal cord: an overview T2 - Axone TI - The tethered spinal cord: an overview VL - 11 ID - 4011 ER - TY - JOUR AB - As they grow, children go through different phases of growth and development, and very often due to various unspecified outside influences, they are overloaded with weight. Heavy backpacks and its correlation to different types of bad posture, as well as pain in particular parts of the back, has been an important issue in the past several years. The aim of this research was to determine average backpack weight in correlation to children's weight in primary school. Also, the aim was to determine if there were some differences between pupils of the first, second, third, and fourth grade of primary school. Further on, it aimed at answering the question whether there was some correlation between the already determined relative backpack weight and the mentioned pain intensity while carrying the backpack. The research was conducted on a sample of 252 primary school pupils (boys and girls). Body weight and backpack weight were measured, and a short interview was also conducted. The short interview concerned feelings, intensity and pain location while carrying and the way they carry the backpack. The results indicate that the average values of the correlation between the backpack weight and the body weight (%) compared with the maximum allowed limit of 10%, in all grades, are in average (16.72%) over the limit, resulting with the maximum rate of 29.17% in grade 1. Out of the total number of pupils, 93.1% responded that they carry the backpack on both shoulders. Out of the whole sample, 87(31.4%) of them said that they feel pain while carrying the backpack. The majority (18.4%) of subjects felt pain in their lower back. The youngest children in this sample, more precisely, those in grade 1, felt the most pain of high intensity, which is probably due to the fact that their backpack, compared to their body weight, was too heavy. AN - WOS:000323990800003 AU - Pausic, J. AU - Kujundzic, H. AU - Penjak, A. IS - 2 N1 - Pausic, Jelena Kujundzic, Hrvoje Penjak, Ana Penjak, Ana/D-9208-2017; Pausic, Jelena/D-9221-2017 Penjak, Ana/0000-0002-8195-4310; Pausic, Jelena/0000-0001-7360-7282 1848-5197 PY - 2013 SN - 1848-5189 SP - 275-287 ST - Possible Influences of a Heavy Backpack on Back Pain Syndrome in Primary School Children T2 - Croatian Journal of Education-Hrvatski Casopis Za Odgoj I Obrazovanje TI - Possible Influences of a Heavy Backpack on Back Pain Syndrome in Primary School Children UR - ://WOS:000323990800003 VL - 15 ID - 2393 ER - TY - JOUR AB - Epidemiological and cross-sectional studies have shown that post-traumatic stress disorder symptoms (PTSS) are common and impairing in youth with chronic pain. Yet, the co-occurrence of PTSS and pediatric chronic pain has not been examined longitudinally, which has limited understanding of theoretically proposed mechanisms (eg, sleep disturbance) underlying the PTSS-pain relationship over time. This longitudinal study aimed to fill this gap. Participants included 138 youth (M-age = 14.29, 75% girls) referred to a tertiary-level outpatient chronic pain program and one of their parents. At baseline, youth reported their pain intensity and interference, PTSS, and subjective sleep disturbances (ie, sleep quality and insomnia). Youth and parents completed semistructured diagnostic interviews to determine the child's post-traumatic stress disorder diagnostic status, and youth completed an objective assessment of sleep patterns for 7 days using actigraphy. At 3-month follow-up, youth once again completed the diagnostic interview and reported their pain intensity, pain interference, and PTSS. Partially latent cross-lagged structural equation panel models revealed that, controlling for pain intensity, pain interference and PTSS co-occurred at baseline, but not at follow-up (while controlling for baseline levels). Higher levels of baseline PTSS were predictive of increases in pain interference at follow-up. Furthermore, subjective sleep disturbances mediated the relationship between baseline PTSS and follow-up pain interference. These findings lend support to conceptual models of PTSS-pain co-occurrence and highlight a critical need to assess and address trauma and sleep disturbances in youth with chronic pain. AN - WOS:000524199500017 AU - Pavlova, M. AU - Kopala-Sibley, D. C. AU - Nania, C. AU - Mychasiuk, R. AU - Christensen, J. AU - McPeak, A. AU - Tomfohr-Madsen, L. AU - Katz, J. AU - Palermo, T. M. AU - Noel, M. DA - Apr DO - 10.1097/j.pain.0000000000001769 IS - 4 N1 - Pavlova, Maria Kopala-Sibley, Daniel C. Nania, Cara Mychasiuk, Richelle Christensen, Jennaya McPeak, Allison Tomfohr-Madsen, Lianne Katz, Joel Palermo, Tonya M. Noel, Melanie 1872-6623 PY - 2020 SN - 0304-3959 SP - 821-830 ST - Sleep disturbance underlies the co-occurrence of trauma and pediatric chronic pain: a longitudinal examination T2 - Pain TI - Sleep disturbance underlies the co-occurrence of trauma and pediatric chronic pain: a longitudinal examination UR - ://WOS:000524199500017 VL - 161 ID - 1831 ER - TY - JOUR AB - OBJECTIVES: The current study aimed to explore relationships among self-reported menstrual pain ratings, acute laboratory pain, pain catastrophizing, and anxiety sensitivity in a sample of girls without pain (No Pain group) and girls with a chronic pain condition (Chronic Pain group). SETTING: A laboratory at an off-campus Medical School office building. SUBJECTS: Eighty-four postmenarchal girls (43 No Pain, 41 Chronic Pain) ages 10-17 participated in the study. METHODS: All participants completed self-report questionnaires assessing menstrual pain, pain catastrophizing, and anxiety sensitivity and completed a cold pressor task. Pain intensity during the task was rated on a 0 (no pain) to 10 (worst pain possible) numeric rating scale. RESULTS: After controlling for age, average menstrual pain ratings (without medication) were significantly correlated with cold pressor pain intensity for the No Pain group only. In the Chronic Pain group, menstrual pain ratings were significantly correlated with pain catastrophizing and anxiety sensitivity. In a multiple linear regression analysis, after controlling for age, only pain catastrophizing emerged as a significant predictor of menstrual pain ratings in the Chronic Pain group. CONCLUSION: Results demonstrate differences in relationships among menstrual pain, acute laboratory pain, and psychological variables in girls with no pain compared with girls with chronic pain. In addition, pain catastrophizing may be a particularly salient factor associated with menstrual pain in girls with chronic pain that warrants further investigation. AN - 26218344 AU - Payne, L. A. AU - Rapkin, A. J. AU - Lung, K. C. AU - Seidman, L. C. AU - Zeltzer, L. K. AU - Tsao, J. C. C2 - PMC4791196 C6 - NIHMS765904 DA - Jan DO - 10.1111/pme.12869 DP - NLM ET - 2015/07/29 IS - 1 KW - Adaptation, Psychological Adolescent Anxiety/psychology Catastrophization/diagnosis/*psychology Chronic Pain/*psychology Dysmenorrhea/diagnosis/*physiopathology Female Humans Pain Measurement/methods Pain Threshold/psychology Self Report Surveys and Questionnaires LA - eng N1 - 1526-4637 Payne, Laura A Rapkin, Andrea J Lung, Kirsten C Seidman, Laura C Zeltzer, Lonnie K Tsao, Jennie C I K23 HD077042/HD/NICHD NIH HHS/United States KL2 TR000122/TR/NCATS NIH HHS/United States R01 DE012754/DE/NIDCR NIH HHS/United States K23HD077042/HD/NICHD NIH HHS/United States KL2TR000122/TR/NCATS NIH HHS/United States R01DE012754/DE/NIDCR NIH HHS/United States Journal Article Research Support, N.I.H., Extramural Pain Med. 2016 Jan;17(1):16-24. doi: 10.1111/pme.12869. PY - 2016 SN - 1526-2375 (Print) 1526-2375 SP - 16-24 ST - Pain Catastrophizing Predicts Menstrual Pain Ratings in Adolescent Girls with Chronic Pain T2 - Pain Med TI - Pain Catastrophizing Predicts Menstrual Pain Ratings in Adolescent Girls with Chronic Pain VL - 17 ID - 3523 ER - TY - JOUR AB - Prescription opioid use has increased in recent decades. Although opioids provide effective pain control, their use may be associated with the risk of misuse. Opioid misuse (OM) is prevalent among adolescents and young adults (AYAs). Opioids are necessary to treat cancer-related pain; however, oncology patients are not immune to medication misuse. Research examining OM among AYAs with cancer is scarce. This article examines the risk factors described in the general adult and adolescent medication abuse literature and aims to provide recommendations for practice in the AYA oncology population. The following risk factors should be examined in AYA oncology patients to determine their relevance: age, sex, behavioral and academic problems, psychological conditions, and a history of illicit drug use/abuse. To maintain the delicate balance of providing adequate pain relief while protecting patients from the risk of OM, clinicians must consider potential risk factors, motivating factors, and individual behaviors. Placing these challenges in perspective, this review provides clinical considerations, recommendations, and intervention strategies for OM prevention in AYA oncology patients. AD - Department of Psychology, University of Mississippi, University, Mississippi. Department of Psychology, St Jude Children's Research Hospital, Memphis, Tennessee. Division of Anesthesiology, Department of Pediatric Medicine, St Jude Children's Research Hospital, Memphis, Tennessee. AN - 27435441 AU - Peck, K. R. AU - Ehrentraut, J. H. AU - Anghelescu, D. L. DA - May-Jun DO - 10.5055/jom.2016.0333 DP - NLM ET - 2016/07/21 IS - 3 KW - Adolescent *Analgesics, Opioid/administration & dosage/adverse effects/therapeutic use Cancer Pain/*drug therapy/psychology *Drug Overdose/epidemiology/etiology/prevention & control Humans Prescription Drug Misuse/prevention & control/*statistics & numerical data Prevalence Risk Factors Young Adult LA - eng N1 - Peck, Kelly R Ehrentraut, Jennifer Harman Anghelescu, Doralina L Journal Article Review United States J Opioid Manag. 2016 May-Jun;12(3):205-16. doi: 10.5055/jom.2016.0333. PY - 2016 SN - 1551-7489 (Print) 1551-7489 SP - 205-16 ST - Risk factors for opioid misuse in adolescents and young adults with focus on oncology setting T2 - J Opioid Manag TI - Risk factors for opioid misuse in adolescents and young adults with focus on oncology setting VL - 12 ID - 3140 ER - TY - JOUR AB - BACKGROUND: Some domains of the questionnaires used to measure symptoms and quality of life (QOL) in patients with advanced cancer seem to measure similar dimensions or constructs, so it would be useful for clinicians to demonstrate the interchangeability of equivalent domains of the questionnaires in measuring the same constructs. OBJECTIVE: This study investigated the reliability and concurrent validity of the Palliative Outcome Scale (POS), the Rotterdam Symptom Checklist (RSCL), and the Brief Pain Inventory (BPI), used to measure symptom control in patients with advanced cancer. DESIGN: This was an evaluative study. SETTING/SUBJECTS: Subjects were patients with advanced cancer attended by Spanish primary care physicians. MEASUREMENTS: Secondary analysis was performed of 117 outpatients who completed the POS, BPI, and RSCL at two different times, with an interval of 7 to 10 days. Bland and Altman analyses and plot, repeatability coefficient, as well as Spearman correlations were carried out. RESULTS: There were 117 included patients. Mean age was 69.4 (11.5) years, gender was 60% male, 37.6% completed only elementary school, diagnoses were mainly digestive and lung cancer, with a low functional rate and presence of oncologic pain. First and second questionnaire rounds showed significant correlations and agreement. Agreement was shown between pain intensity of BPI and pain and physical scales of RSCL, and between physical symptoms of RSCL and of POS, with significant correlations in equivalent dimensions. CONCLUSION: BPI, POS, and RSCL have shown adequate reliability and moderate concurrent validity among them. AD - Primary Care Health Centre, National Health Service, Valencia, Spain. mpelayo@ribera10.com AN - 23808642 AU - Pelayo-Alvarez, M. AU - Perez-Hoyos, S. AU - Agra-Varela, Y. C2 - PMC3717199 DA - Aug DO - 10.1089/jpm.2012.0625 DP - NLM ET - 2013/07/03 IS - 8 KW - Aged Checklist Female Humans Male Neoplasms/*complications/psychology/therapy *Outcome and Process Assessment, Health Care Pain Management/*methods/standards Pain Measurement/*methods Palliative Care/*methods Primary Health Care/*methods/standards *Quality of Life Reproducibility of Results Spain Surveys and Questionnaires Terminally Ill LA - eng N1 - 1557-7740 Pelayo-Alvarez, Marta Perez-Hoyos, Santiago Agra-Varela, Yolanda Evaluation Study Journal Article Research Support, Non-U.S. Gov't J Palliat Med. 2013 Aug;16(8):867-74. doi: 10.1089/jpm.2012.0625. Epub 2013 Jun 28. PY - 2013 SN - 1096-6218 (Print) 1557-7740 SP - 867-74 ST - Reliability and concurrent validity of the Palliative Outcome Scale, the Rotterdam Symptom Checklist, and the Brief Pain Inventory T2 - J Palliat Med TI - Reliability and concurrent validity of the Palliative Outcome Scale, the Rotterdam Symptom Checklist, and the Brief Pain Inventory VL - 16 ID - 3735 ER - TY - JOUR AB - Objectives: To assess the prevalence of low back pain (LBP) in adolescents and the clinical features of LBP in 2 European countries and to evaluate the effect of LBP on health-related quality of life (HRQOL) using standardized validated generic and disease-specific instruments. Design: Cross-sectional study. Setting: Secondary schools of Barcelona, Spain, and Fribourg, Switzerland. Participants: Representative sample of adolescents from the 2 cities. Intervention: Selected adolescents completed a questionnaire including a generic HRQOL (KIDSCREEN-52) and 2 LBP-specific instruments. Main Outcome Measures: Results of KIDSCREEN-52, the Roland-Morris Disability Questionnaire, and the Hanover Functional Ability Questionnaire. Results: A total of 1470 adolescents (52.6% male) with a mean (SD) age of 15.05 (1.17) years completed the questionnaires (response rate, 85.1%). Low back pain was reported by 587 adolescents (39.8%): isolated LBP in 250 (42.6%), LBP plus other pain in 271(46.2%), LBP plus whole-body pain in 50 (8.5%, and unclassifiable LBP in 16 (2.7%). Five hundred adolescents (34.7%) reported no pain, and 369 (25.6%) reported other pain without LBP. In those with isolated LBP, the percentage of adolescent boys was higher (54.6%; P<.001) and the LBP was mildest. In those with LBP plus whole-body pain, the percentage of adolescent girls was higher (62%; P<.001) and LBP was most severe. All KIDSCREEN scores in the group with LBP plus whole-body pain were significantly lower than in the other groups (effect size, 0.52-1.24). No differences were found between the groups who reported isolated pain, no pain, or other pain with no LBP. On the LBP-specific instruments, adolescents who reported LBP plus other pain had significantly poorer scores (P<.001) compared with those with isolated LBP but better scores (P<.001) than those with LBP plus whole-body pain. Conclusions: Low back pain in adolescents is a prevalent symptom with overall low associated disability and little effect on health-related quality of life. A subset of adolescents in whom LBP is associated with whole-body pain report significant impairment and deserve more attention. AN - WOS:000262179000011 AU - Pellise, F. AU - Balague, F. AU - Rajmil, L. AU - Cedraschi, C. AU - Aguirre, M. AU - Fontecha, C. G. AU - Pasarin, M. AU - Ferrer, M. DA - Jan DO - 10.1001/archpediatrics.2008.512 IS - 1 N1 - Pellise, Ferran Balague, Federico Rajmil, Luis Cedraschi, Christine Aguirre, Mario Fontecha, Cesar G. Pasarin, Maribel Ferrer, Montse Fontecha, Cesar G/A-1414-2015; Ferrer, Montse/A-5510-2010; Pellise, Ferran/D-4488-2016 Fontecha, Cesar G/0000-0002-6363-433X; Ferrer, Montse/0000-0001-9867-7391; Aguirre-Canyadell, Marius/0000-0002-3852-338X; Rajmil, Luis/0000-0002-6625-0649; Pellise, Ferran/0000-0002-0644-7757 1538-3628 PY - 2009 SN - 1072-4710 SP - 65-71 ST - Prevalence of Low Back Pain and Its Effect on Health-Related Quality of Life in Adolescents T2 - Archives of Pediatrics & Adolescent Medicine TI - Prevalence of Low Back Pain and Its Effect on Health-Related Quality of Life in Adolescents UR - ://WOS:000262179000011 VL - 163 ID - 2621 ER - TY - JOUR AB - OBJECTIVES: Fear of movement (ie, kinesiophobia) has emerged as a significant predictor of pain-related outcomes including disability and psychologic distress across various types of pain (eg, back pain, headache, fibromyalgia, complex regional pain syndrome). However, no research has examined the prevalence of kinesiophobia in adults with sickle cell disease (SCD). The purpose of this study was to assess the degree of kinesiophobia reported by African American men and women with SCD and to determine whether kinesiophobia is related to pain and psychologic distress in this population. METHODS: Sixty-seven men and women with SCD recruited from a comprehensive sickle cell treatment program in a large academic medical center completed questionnaires that assess fear of movement, pain and pain interference, and psychologic distress. RESULTS: Participants reported levels of kinesiophobia (M=30.48, SD=7.55) that were comparable to those obtained for patients with low back pain and fibromyalgia. Although pain levels did not differ by sex, men reported greater kinesiophobia than women (P=0.02). As hypothesized, higher levels of kinesiophobia were associated with greater psychologic distress, particularly Phobic Anxiety (r=0.35), Psychoticism (r=0.29), Somatization (r=0.45), Anxiety (r=0.35), Obsessive-compulsive (r=0.34), Interpersonal Sensitivity (r=0.25), Depression (r=0.29), and all 3 summary indices of the SCL-90-R (all Ps<0.05). DISCUSSION: Although and historically, pain associated with SCD has not been considered in the context of fear of movement, findings suggest that both kinesiophobia and sex are relevant constructs for consideration in understanding pain-related outcomes in SCD. Though our results require replication, this study suggests that greater kinesiophobia is associated with greater pain and psychologic distress. AD - Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27705, USA. AN - 17885350 AU - Pells, J. AU - Edwards, C. L. AU - McDougald, C. S. AU - Wood, M. AU - Barksdale, C. AU - Jonassaint, J. AU - Leach-Beale, B. AU - Byrd, G. AU - Mathis, M. AU - Harrison, M. O. AU - Feliu, M. AU - Edwards, L. Y. AU - Whitfield, K. E. AU - Rogers, L. DA - Oct DO - 10.1097/AJP.0b013e31814da3eb DP - NLM ET - 2007/09/22 IS - 8 KW - Adolescent Adult African Americans Aged Anemia, Sickle Cell/*complications/epidemiology/*psychology Body Mass Index Chronic Disease Cross-Sectional Studies Female Humans Income Longitudinal Studies Male Mental Disorders/psychology Middle Aged Movement Pain/epidemiology/etiology/*psychology Pain Measurement Phobic Disorders/epidemiology/etiology/*psychology Sex Characteristics Socioeconomic Factors Surveys and Questionnaires LA - eng N1 - Pells, Jennifer Edwards, Christopher L McDougald, Camela S Wood, Mary Barksdale, Crystal Jonassaint, Jude Leach-Beale, Brittani Byrd, Goldie Mathis, Markece Harrison, Myleme O Feliu, Miriam Edwards, Lekisha Y Whitfield, Keith E Rogers, Lesco Journal Article United States Clin J Pain. 2007 Oct;23(8):707-13. doi: 10.1097/AJP.0b013e31814da3eb. PY - 2007 SN - 0749-8047 (Print) 0749-8047 SP - 707-13 ST - Fear of movement (kinesiophobia), pain, and psychopathology in patients with sickle cell disease T2 - Clin J Pain TI - Fear of movement (kinesiophobia), pain, and psychopathology in patients with sickle cell disease VL - 23 ID - 3553 ER - TY - JOUR AB - Background/Aims We hypothesize that patients with functional gastrointestinal disorders (FGID) drink less water volume than healthy subjects during water load test. We evaluated and compared the water load test in students with and without FGID using the Rome III questionnaire. Methods We performed the water load test in 142 students from two schools in Colombia. Students were diagnosed using the Spanish version of the Rome III questionnaire. Students drank water ad libitum for 3 min or until pain, satiety, or vomiting occurred. We correlated anthropometric variables with water volumes drunk. We recorded symptoms like pain and nausea, before and after the water load test. Results We evaluated 142 students, with a mean age of 12.1 +/- 0.2 years and 59.9% girls. Mean water volume drunk was 459 +/- 22 mL. There was no significant difference between water volume drunk by students with and without FGID (466 +/- 36 vs. 453 +/- 27 mL,p = 0.108). We found a significant correlation between water volume drunk and gender, age, weight, height, and body mass index. Conclusions Students with and without FGID ingest similar volumes of water. Test adverse effects are minimal, and the test is safe to perform and well tolerated. AN - WOS:000570438000001 AU - Peralta-Palmezano, J. J. AU - Guerrero-Lozano, R. DO - 10.1007/s12664-020-01073-4 N1 - Peralta-Palmezano, Juan Javier Guerrero-Lozano, Rafael PERALTA PALMEZANO, JUAN JAVIER/0000-0001-6766-8679; Guerrero-Lozano, Rafael/0000-0003-0894-8309 0975-0711 SN - 0254-8860 ST - The water load test in school children and adolescents with functional gastrointestinal disorders T2 - Indian Journal of Gastroenterology TI - The water load test in school children and adolescents with functional gastrointestinal disorders UR - ://WOS:000570438000001 ID - 1797 ER - TY - JOUR AB - BACKGROUND/AIMS: The epidemiology of functional gastrointestinal disorders (FGIDs) in developed and developing countries involves a high prevalence of constipation and irritable bowel syndrome. This study examined the prevalence of functional gastrointestinal disorders in schoolchildren and adolescents in Colombia using the Rome III criteria. METHODS: A cross-sectional study was performed on Colombian children between 8 and 17 years old. The Spanish version of the Questionnaire on Pediatric Gastrointestinal Symptoms-Rome III Version self-report form was answered by students from two schools. The prevalence of FGID was calculated and correlation tests were conducted among the variables analyzed. RESULTS: A total of 864 children with a mean age of 12.5±2.5 years were analyzed; 50.7% were female. Two hundred and fifty-nine children (30%) had at least one FGID, and of these, 163 were female (62.9%). Sixty-nine children had two or more FGIDs (8%). Functional constipation was the most prevalent disorder (13.2%), followed in order by abdominal migraine (8.3%), irritable bowel syndrome (6.9%), and aerophagia (3.1%). A significantly higher prevalence of FGID was observed in females (p=0.000). No significant difference was observed between the age groups or type of school they attended. CONCLUSIONS: The overall prevalence of FGID in the sample was 30%, with functional constipation being the most common. These results are similar to those of other prevalence studies reported elsewhere. AD - Department of Pediatrics, Universidad Nacional de Colombia, Bogotá, Colombia. AN - 31030457 AU - Peralta-Palmezano, J. J. AU - Guerrero-Lozano, R. DA - Apr 25 DO - 10.4166/kjg.2019.73.4.207 DP - NLM ET - 2019/04/30 IS - 4 KW - Adolescent Child Colombia/epidemiology Constipation/diagnosis/epidemiology Cross-Sectional Studies Female Gastrointestinal Diseases/*diagnosis/epidemiology Humans Irritable Bowel Syndrome/diagnosis/epidemiology Male Migraine Disorders/diagnosis/epidemiology Surveys and Questionnaires Constipation Developing countries Epidemiology Irritable bowel syndrome Schools LA - eng N1 - 2233-6869 Peralta-Palmezano, Juan Javier Guerrero-Lozano, Rafael Journal Article Korea (South) Korean J Gastroenterol. 2019 Apr 25;73(4):207-212. doi: 10.4166/kjg.2019.73.4.207. PY - 2019 SN - 1598-9992 SP - 207-212 ST - Prevalence of Functional Gastrointestinal Disorders in School Children and Adolescents T2 - Korean J Gastroenterol TI - Prevalence of Functional Gastrointestinal Disorders in School Children and Adolescents VL - 73 ID - 3526 ER - TY - JOUR AB - BACKGROUND/AIMS: We hypothesize that patients with functional gastrointestinal disorders (FGID) drink less water volume than healthy subjects during water load test. We evaluated and compared the water load test in students with and without FGID using the Rome III questionnaire. METHODS: We performed the water load test in 142 students from two schools in Colombia. Students were diagnosed using the Spanish version of the Rome III questionnaire. Students drank water ad libitum for 3 min or until pain, satiety, or vomiting occurred. We correlated anthropometric variables with water volumes drunk. We recorded symptoms like pain and nausea, before and after the water load test. RESULTS: We evaluated 142 students, with a mean age of 12.1 ± 0.2 years and 59.9% girls. Mean water volume drunk was 459 ± 22 mL. There was no significant difference between water volume drunk by students with and without FGID (466 ± 36 vs. 453 ± 27 mL, p = 0.108). We found a significant correlation between water volume drunk and gender, age, weight, height, and body mass index. CONCLUSIONS: Students with and without FGID ingest similar volumes of water. Test adverse effects are minimal, and the test is safe to perform and well tolerated. AD - Department of Pediatrics, Universidad Nacional de Colombia, Bogotá, Colombia. jjperaltap@unal.edu.co. HOMI Fundación Hospital Pediátrico la Misericordia, Bogotá, Colombia. jjperaltap@unal.edu.co. Department of Pediatrics, Universidad Nacional de Colombia, Bogotá, Colombia. AN - 32940846 AU - Peralta-Palmezano, J. J. AU - Guerrero-Lozano, R. DA - Apr DO - 10.1007/s12664-020-01073-4 DP - NLM ET - 2020/09/18 IS - 2 KW - Adverse effects Diagnostic procedure Functional dyspepsia Functional gastrointestinal disorder Gastric emptying Gastrointestinal diseases Gastroparesis Reference values Rome criteria Water consumption LA - eng N1 - 0975-0711 Peralta-Palmezano, Juan Javier Orcid: 0000-0001-6766-8679 Guerrero-Lozano, Rafael Orcid: 0000-0003-0894-8309 Journal Article India Indian J Gastroenterol. 2021 Apr;40(2):162-168. doi: 10.1007/s12664-020-01073-4. Epub 2020 Sep 17. PY - 2021 SN - 0254-8860 SP - 162-168 ST - The water load test in school children and adolescents with functional gastrointestinal disorders T2 - Indian J Gastroenterol TI - The water load test in school children and adolescents with functional gastrointestinal disorders VL - 40 ID - 4190 ER - TY - JOUR AB - OBJECTIVES: The aim of the study was to understand the association of frequent opioid use with disease phenotype and pain pattern and burden in children and adolescents with acute recurrent (ARP) or chronic pancreatitis (CP). METHODS: Cross-sectional study of children <19 years with ARP or CP, at enrollment into the INSPPIRE cohort. We categorized patients as opioid "frequent use" (daily/weekly) or "nonfrequent use" (monthly or less, or no opioids), based on patient and parent self-report. RESULTS: Of 427 children with ARP or CP, 17% reported frequent opioid use. More children with CP (65%) reported frequent opioid use than with ARP (41%, P = 0.0002). In multivariate analysis, frequent opioid use was associated with older age at diagnosis (odds ratio [OR] 1.67 per 5 years, 95% confidence interval [CI] 1.13-2.47, P = 0.01), exocrine insufficiency (OR 2.44, 95% CI 1.13-5.24, P = 0.02), constant/severe pain (OR 4.14, 95% CI 2.06-8.34, P < 0.0001), and higher average pain impact score across all 6 functional domains (OR 1.62 per 1-point increase, 95% CI 1.28-2.06, P < 0.0001). Children with frequent opioid use also reported more missed school days, hospitalizations, and emergency room visits in the past year than children with no frequent use (P < 0.0002 for each). Participants in the US West and Midwest accounted for 83% of frequent opioid users but only 56% of the total cohort. CONCLUSIONS: In children with CP or ARP, frequent opioid use is associated with constant pain, more healthcare use, and higher levels of pain interference with functioning. Longitudinal and prospective research is needed to identify risk factors for frequent opioid use and to evaluate nonopioid interventions for reducing pain and disability in these children. AD - Department of Pediatrics, University of California San Francisco, San Francisco, CA. Department of Anesthesiology & Pain Medicine, University of Washington, Seattle, WA. Department of Pediatrics, University of Utah, Salt Lake City, UT. Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA. Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH. Department of Pediatrics, University of Texas Southwestern, Dallas, TX. Department of Pediatrics, University of Minnesota, Minneapolis, MN. Department of Pediatrics, Texas Children's Hospital, Houston, TX. Harvard University, Boston, MA. Department of Pediatrics, Nationwide Children's Hospital, Columbus, OH. Department of Pediatrics, Sick Kids Hospital, University of Toronto, Toronto, ON, Canada. Department of Pediatrics, University of Pittsburgh, Pittsburgh, PA. Department of Pediatrics, Cedars-Sinai, Los Angeles, CA. Department of Pediatrics, Indiana University, Indianapolis, IN. Department of Pediatrics, Montreal Children's Hospital, McGill University, Montreal, QC, Canada. Department of Pediatric General and Thoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH. School of Women's and Children's Health, Medicine, University of New South Wales, New South Wales, Sydney, Australia. Department of Pediatrics, Massachusetts General Hospital, Boston, MA. Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI. Hadassah University, Jerusalem, Israel. Department of Pediatrics, Children's Hospital Los Angeles, Los Angeles, CA. Department of Biostatistics, University of Iowa, Iowa City, IA. Department of Pediatrics, Washington University, St. Louis, MO. Stead Family Department of Pediatrics, University of Iowa, Iowa City, IA. AN - 31567889 AU - Perito, E. R. AU - Palermo, T. M. AU - Pohl, J. F. AU - Mascarenhas, M. AU - Abu-El-Haija, M. AU - Barth, B. AU - Bellin, M. D. AU - Fishman, D. S. AU - Freedman, S. AU - Gariepy, C. AU - Giefer, M. AU - Gonska, T. AU - Heyman, M. B. AU - Himes, R. W. AU - Husain, S. Z. AU - Lin, T. AU - Liu, Q. AU - Maqbool, A. AU - McFerron, B. AU - Morinville, V. D. AU - Nathan, J. D. AU - Ooi, C. Y. AU - Rhee, S. AU - Schwarzenberg, S. J. AU - Shah, U. AU - Troendle, D. M. AU - Werlin, S. AU - Wilschanski, M. AU - Zheng, Y. AU - Zimmerman, M. B. AU - Lowe, M. AU - Uc, A. C2 - PMC6934913 C6 - NIHMS1540181 Pancreas Foundation; receives royalties from Millipore Inc and UpToDate. Dr. Tanja Gonska received a research grant from Vertex Pharmaceuticals and she is a consultant for Cystic Fibrosis Foundation. Dr. Husain has equity in Prevcon, LLC. Dr. John Pohl is on the speaker’s bureau for Medical Education Resources, Inc. Dr. Melena Bellin is a consultant for ARIEL Precision Medicine and receives research support from ViaCyte and Dexcom. Dr. Chee Y. Ooi is a consultant for Vertex Pharmaceuticals. Dr. Aliye Uc is a member of American Board of Pediatrics, Subboard of Pediatric Gastroenterology and a consultant for Cystic Fibrosis Foundation. The other authors declare no conflicts of interest. DA - Jan DO - 10.1097/mpg.0000000000002502 DP - NLM ET - 2019/10/01 IS - 1 KW - Abdominal Pain/*drug therapy/etiology Acute Disease Adolescent Analgesics, Opioid/*therapeutic use Child Chronic Disease Cross-Sectional Studies Emergency Service, Hospital/statistics & numerical data Female Hospitalization/statistics & numerical data Humans Male Odds Ratio Pain Management/*statistics & numerical data Pancreatitis/*complications Patient Acceptance of Health Care/*statistics & numerical data Phenotype Recurrence LA - eng N1 - 1536-4801 Perito, Emily R Palermo, Tonya M Pohl, John F Mascarenhas, Maria Abu-El-Haija, Maisam Barth, Bradley Bellin, Melena D Fishman, Douglas S Freedman, Steven Gariepy, Cheryl Giefer, Matthew Gonska, Tanja Heyman, Melvin B Himes, Ryan W Husain, Sohail Z Lin, Tom Liu, Quin Maqbool, Asim McFerron, Brian Morinville, Veronique D Nathan, Jaime D Ooi, Chee Y Rhee, Sue Schwarzenberg, Sarah Jane Shah, Uzma Troendle, David M Werlin, Steven Wilschanski, Michael Zheng, Yuhua Zimmerman, Miriam Bridget Lowe, Mark Uc, Aliye K23 DK099253/DK/NIDDK NIH HHS/United States P30 DK054759/DK/NIDDK NIH HHS/United States R21 DK096327/DK/NIDDK NIH HHS/United States U01 DK108334/DK/NIDDK NIH HHS/United States Journal Article Research Support, N.I.H., Extramural J Pediatr Gastroenterol Nutr. 2020 Jan;70(1):106-114. doi: 10.1097/MPG.0000000000002502. PY - 2020 SN - 0277-2116 (Print) 0277-2116 SP - 106-114 ST - Factors Associated With Frequent Opioid Use in Children With Acute Recurrent and Chronic Pancreatitis T2 - J Pediatr Gastroenterol Nutr TI - Factors Associated With Frequent Opioid Use in Children With Acute Recurrent and Chronic Pancreatitis VL - 70 ID - 3059 ER - TY - JOUR AB - BACKGROUND: Adolescent idiopathic scoliosis is one of the most common spinal deformities in children and adolescents requiring extensive surgical intervention. Due to the nature of surgery, spinal fusion increases their risk of experiencing persistent postsurgical pain. Up to 20% of adolescents report pain for months or years after corrective spinal fusion surgery. AIMS: To examine the influence of preoperative psychosocial factors and mRNA expression profiles on persistent postoperative pain in adolescents undergoing corrective spinal fusion surgery. DESIGN: Prospective, longitudinal cohort study. SETTING: Two freestanding academic children's hospitals. METHODS: Utilizing a longitudinal approach, adolescents were evaluated at baseline (preoperatively) and postoperatively at ±1 month and ±4-6 months. Self-report of pain scores, the Pain Catastrophizing Scale-Child, and whole blood for RNA sequencing analysis were obtained at each time point. RESULTS: Of the adolescents enrolled in the study, 36% experienced persistent pain at final postoperative follow-up. The most significant predictors of persistent pain included preoperative pain severity and helplessness. Gene expression analysis identified HLA-DRB3 as having increased expression in children who experienced persistent pain postoperatively, as opposed to those whose pain resolved. A prospective validation study with a larger sample size is needed to confirm these findings. CONCLUSIONS: While adolescent idiopathic scoliosis is not often classified as a painful condition, providers must be cognizant of pre-existing pain and anxiety that may precipitate a negative recovery trajectory. Policy and practice change are essential for early identification and subsequent intervention. AD - Center for the Advancement in Managing Pain, University of Connecticut School of Nursing, Storrs, Connecticut. Electronic address: perrym2@email.chop.edu. Department of Anesthesiology, Critical Care, and Pain Medicine, Center for Pain and the Brain (P.A.I.N. Group), Boston Children's Hospital, Boston, Massachusetts; Department of Psychiatry, Biobehavioral Pediatric Pain Lab, Boston Children's Hospital, Boston, Massachusetts; Department of Psychiatry, Harvard Medical School, Boston, Massachusetts. Center for the Advancement in Managing Pain, University of Connecticut School of Nursing, Storrs, Connecticut; Department of Genetics and Genome Science, University of Connecticut School of Medicine, Storrs, Connecticut. Center for the Advancement in Managing Pain, University of Connecticut School of Nursing, Storrs, Connecticut; Department of Neuroscience, University of Connecticut School of Medicine, Storrs, Connecticut. Computational Biology Core, University of Connecticut Institute for Systems Genomics, Storrs, Connecticut. Department of Psychiatry, Biobehavioral Pediatric Pain Lab, Boston Children's Hospital, Boston, Massachusetts. Center for the Advancement in Managing Pain, University of Connecticut School of Nursing, Storrs, Connecticut. AN - 32771349 AU - Perry, M. AU - Sieberg, C. B. AU - Young, E. E. AU - Baumbauer, K. AU - Singh, V. AU - Wong, C. AU - Starkweather, A. DA - Feb DO - 10.1016/j.pmn.2020.05.007 DP - NLM ET - 2020/08/11 IS - 1 LA - eng N1 - 1532-8635 Perry, Mallory Sieberg, Christine B Young, Erin E Baumbauer, Kyle Singh, Vijender Wong, Cindy Starkweather, Angela K23 GM123372/GM/NIGMS NIH HHS/United States Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't United States Pain Manag Nurs. 2021 Feb;22(1):44-49. doi: 10.1016/j.pmn.2020.05.007. Epub 2020 Aug 6. PY - 2021 SN - 1524-9042 SP - 44-49 ST - The Potential Role of Preoperative Pain, Catastrophizing, and Differential Gene Expression on Pain Outcomes after Pediatric Spinal Fusion T2 - Pain Manag Nurs TI - The Potential Role of Preoperative Pain, Catastrophizing, and Differential Gene Expression on Pain Outcomes after Pediatric Spinal Fusion VL - 22 ID - 4116 ER - TY - JOUR AB - The present study investigates the somatization symptoms among grammar school students. High school students (N=218) from a convenience sample school were asked to complete The Somatization Scale. Data analysis showed that girls reported somatization symptoms more frequently than boys. The analysis showed that 1.4% of students felt some of the somatic symptoms on a daily basis, while 6.9% of students had such symptoms 2-3 times a week. Other students reported physical symptoms less frequently. 41.3% of students reported having somatic symptoms once a week and 46.8% of the students complained of somatic symptoms once or twice a month. Only 3.2% of students said that they had never experienced such symptoms. The most common somatic symptoms in adolescence are headaches and fatigue, while the rarest physical symptom is abdominal pain. Contemporary authors associated somatization tendencies with stressful situations in school. Therefore, it is important that parents, teachers and school counselors are familiar with the frequency and potential causes of somatic symptoms in adolescence. AN - WOS:000348823700009 AU - Petak, A. AU - Brajsa-Zganec, A. DA - Dec IS - 4 N1 - Petak, Ana Brajsa-Zganec, Andreja Brajsa-Zganec, Andreja/0000-0003-0846-6297 1848-5197 PY - 2014 SN - 1848-5189 SP - 1119-1146 ST - The Somatization Symptoms among Grammar School Students T2 - Croatian Journal of Education-Hrvatski Casopis Za Odgoj I Obrazovanje TI - The Somatization Symptoms among Grammar School Students UR - ://WOS:000348823700009 VL - 16 ID - 2269 ER - TY - JOUR AB - Since the introduction of the Gate-Control-Theory by Melzack and Wall in 1965, pain has been recognized and conceptualized as a multifaceted, complex phenomenon comprising physical, psychological and social components. Pain in childhood has gained much attention only in recent years, although a considerable portion of pre- and elementary school children suffer from pain. A particular characteristic of research and treatment of pain in children is a need to consider their biological, psychological, and social developmental conditions. A child's cognitive maturity influences the way in which pain is experienced and managed, and the extent to which the child complies with the diagnostic and treatment regimes. Additionally, pain diagnostic methods and behavioral medicine treatment procedures need to pay attention to the child's physiological and psychological development status, as well as the child's social and family context. Behavioral medicine interventions for pain management in children with acute pain (e. g. injury, surgery, invasive procedure) and chronic or recurrent pain (i.e. neuralgies, polyarthritics, headache and abdominal pain) have been used successfully, especialy the child-adapted relaxation and cognitive procedures. AN - WOS:A1996UE36300002 AU - Petermann, F. AU - Wiedebusch, S. AU - Kroll, T. AU - Muhlig, S. DA - Jan IS - 1 N1 - Petermann, F Wiedebusch, S Kroll, T Muhlig, S 2190-6238 PY - 1996 SN - 0033-3042 SP - 15-29 ST - Pain in childhood: Developmental and behavioral medical considerations in pain diagnostic and management T2 - Psychologische Rundschau TI - Pain in childhood: Developmental and behavioral medical considerations in pain diagnostic and management UR - ://WOS:A1996UE36300002 VL - 47 ID - 2931 ER - TY - JOUR AB - Sickle cell disease (SCD) is associated with impaired cognitive and academic functioning, yet prevalence rates of educational needs and accommodations are not known. The Hematology-Oncology Psycho-Educational Needs Assessment was administered to 72 parents of youth, ages 5 to 17, with SCD. Half of the parents identified concerns about their children's learning; however, only 36% had undergone testing for learning problems, and only 26% had individualized education plans. Many parents (33%) reported concerns about attention/memory, and 36% of youth had failed a grade. Of 33 participants referred for neuropsychological evaluation, only 13 completed testing, which revealed below-average IQ and achievement scores. Considerable morbidity was reported; one third of participants missed over 20 school days per year, and 42% reported disease-related difficulties participating in school. Many youth with SCD present cognitive, academic, and functional difficulties, for which universal screening may promote earlier detection and psycho-educational intervention. AN - WOS:000230066100004 AU - Peterson, C. C. AU - Palermo, T. M. AU - Swift, E. AU - Beebe, A. AU - Drotar, D. DA - Spr DO - 10.1207/s15326888chc3402_4 IS - 2 N1 - Peterson, CC Palermo, TM Swift, E Beebe, A Drotar, D 1532-6888 PY - 2005 SN - 0273-9615 SP - 133-148 ST - Assessment of psycho-educational needs in a clinical sample of children with sickle cell disease T2 - Childrens Health Care TI - Assessment of psycho-educational needs in a clinical sample of children with sickle cell disease UR - ://WOS:000230066100004 VL - 34 ID - 2772 ER - TY - JOUR AB - Background Headache disorders are highly prevalent worldwide, but not so well investigated in children and adolescents as in adults: few studies have included representative nationwide samples. No data exist for Austria until now. In a representative sample of children and adolescents in Austria, we estimated the prevalence and attributable burden of headache disorders, including the new diagnostic category of "undifferentiated headache" (UdH) defined as mild headache lasting less than 1 hour. Methods Within the context of a broader national mental health survey, children and adolescents aged 10-18 years were recruited from purposively selected schools. Mediated self-completed questionnaires included sociodemographic enquiry (gender, age, socioeconomic status, family constellation, residence [urban or rural] and migration background). Prevalence and attributable burden of all headache, UdH, migraine (definite plus probable), tension-type headache (TTH: definite plus probable) and headache on >= 15 days/month (H15+) were assessed using the Headache-Attributed Restriction, Disability, Social Handicap and Impaired Participation (HARDSHIP) questionnaire for children and adolescents. Health-related quality of life (HrQoL) was assessed using the KIDSCREEN questionnaire. Results Of 7643 selected pupils, 3386 (44.3%) completed the questionnaires. The 1-year prevalence of headache was 75.7%, increasing with age and higher in girls (82.1%) than in boys (67.7%; p < 0.001). UdH, migraine, TTH and H15+ were reported by 26.1%, 24.2%, 21.6% and 3.0% of participants. Attributable burden was high, with 42% of those with headache experiencing restrictions in daily activities. Medication use (50% overall) was highest in H15+ (67%) and still considerable in UdH (29%). HrQoL was reduced for all headache types except UdH. Participants in single parent or patchwork families had a higher probability of migraine (respectively, OR 1.5, p < 0.001; OR 1.5, p < 0.01). Participants with a migration background had a lower probability of TTH (OR 0.7, p < 0.01). Conclusions Headache disorders are both very common and highly burdensome in children and adolescents in Austria. This study contributes to the global atlas of headache disorders in these age groups, and corroborates and adds knowledge of the new yet common and important diagnostic category of UdH. The findings call for action in national and international health policies, and for further epidemiological research. AN - WOS:000494820300001 AU - Philipp, J. AU - Zeiler, M. AU - Wober, C. AU - Wagner, G. AU - Karwautz, A. F. K. AU - Steiner, T. J. AU - Wober-Bingol, C. C7 - 101 DA - Dec DO - 10.1186/s10194-019-1050-8 IS - 1 N1 - Philipp, Julia Zeiler, Michael Woeber, Christian Wagner, Gudrun Karwautz, Andreas F. K. Steiner, Timothy J. Wober-Bingol, Cicek Wober, Christian/I-3574-2019 Philipp, Julia/0000-0003-0992-6865; Wober, Christian/0000-0003-1382-1978; Zeiler, Michael/0000-0002-7087-6134; karwautz, andreas/0000-0001-9053-998X; Wagner, Gudrun/0000-0002-4845-9684 1129-2377 PY - 2019 SN - 1129-2369 ST - Prevalence and burden of headache in children and adolescents in Austria - a nationwide study in a representative sample of pupils aged 10-18 years T2 - Journal of Headache and Pain TI - Prevalence and burden of headache in children and adolescents in Austria - a nationwide study in a representative sample of pupils aged 10-18 years UR - ://WOS:000494820300001 VL - 20 ID - 1870 ER - TY - JOUR AB - OBJECTIVE: To investigate the prevalence of medication overuse headache (MOH) in a group of children and adolescents seen for headache in a third-level center in Italy. BACKGROUND: Epidemiological studies indicate a prevalence of MOH in children and adolescents between 0.3 and 0.5%; no data are available for the Italian population. METHODS: We studied a group of first-seen children and adolescents (118 patients, 43.2% male and 56.8% female, mean age: 11.9 years). A detailed history was taken, using criteria defined by Olesen et al to assess the presence of MOH. Statistical correlations between demographic and diagnostic variables were assessed. RESULTS: Eleven (9.3%) of our patients presented MOH; in the group with chronic daily headache, the prevalence raised to 20.8%. At follow up, after introduction of a more rationale treatment, most patients improved, but 2 of them reported a worsening of their headache. CONCLUSIONS: We believe that a strong warning regarding medication overuse in headache therapy is essential for pediatricians and neuropsychiatrists. AU - Piazza, Fausta AU - Chiappedi, Matteo AU - Maffioletti, Erika AU - Galli, Federica AU - Balottin, Umberto DA - 2012/12//Nov- undefined DO - 10.1111/j.1526-4610.2012.02221.x DP - PubMed IS - 10 J2 - Headache KW - adolescence child chronic daily headache Female Headache Disorders, Secondary Humans Italy Male medication overuse headache prevalence Schools Students LA - eng PY - 2012 SN - 1526-4610 SP - 1506-1510 ST - Medication overuse headache in school-aged children T2 - Headache TI - Medication overuse headache in school-aged children: more common than expected? UR - http://www.ncbi.nlm.nih.gov/pubmed/22822711 VL - 52 ID - 77 ER - TY - JOUR AB - The author investigated the prevalence of some common psychosomatic symptoms and self-perceived health in a sample of secondary school students in Szeged, Hungary. The sample (n = 1039, 14-19 years of age) was stratified by school type and sex. Self-completed questionnaire was used as a method of data collection. Two main purpose directed the study. First, to detect the most frequent psychosomatic symptoms and to experience how the secondary students evaluate their own health. Second, to investigate the role of psychological and social factors affecting the occurrence of psychosomatic symptoms and self-perceived health by using multivariate technique. In both sexes, chronic fatigue proved to be the most frequent psychosomatic symptoms which was followed by tension headache and lower back-pain in girls, while among boys lower back-pain and sleeping problems were reported as frequent symptoms. Comparing with the data of a previous research on university students, the secondary school students reported more symptoms, though they perceived their own health higher. In the background of the somatization both psychological (dysfunctional attitudes or inadequate coping) and social (father's unemployment or low level of social support from father) can be found beyond the developmental characteristics of the adolescence (e.g. a tendency for introspection). In case of the diagnose of psychosomatic symptoms in clinical practice there is a need for thinking about the social or psychological affecting factors and seeking professional help from a psychologist or social worker, if it is necessary. AD - Pszichiátriai Klinika Magatartástudományi és Orvosi Pszchológiai Csoportja, Szent-Györgyi Albert Orvostudományi Egyetem, Szeged. AN - 10412265 AU - Pikó, B. DA - Jun 6 DP - NLM ET - 1999/07/21 IS - 23 KW - Adolescent Adolescent Psychiatry Child Female Humans Hungary/epidemiology Male Psychology, Adolescent Psychophysiologic Disorders/*diagnosis/epidemiology/psychology *Self-Assessment Students/*psychology LA - hun N1 - Pikó, B English Abstract Journal Article Review Hungary Orv Hetil. 1999 Jun 6;140(23):1297-304. OP - Pszichoszomatikus tünetek és a szubjektív egészségértékelés epidemiológiája középiskolások körében. PY - 1999 SN - 0030-6002 (Print) 0030-6002 SP - 1297-304 ST - [Epidemiology of psychosomatic symptoms and subjective health evaluation among secondary school students] T2 - Orv Hetil TI - [Epidemiology of psychosomatic symptoms and subjective health evaluation among secondary school students] VL - 140 ID - 3550 ER - TY - JOUR AB - Background and aims There is a growing body of evidence, that pain is common at school age. Less is known about the repeatability of pain questionnaires for children. This study aimed to assess the test-retest repeatability of the Finnish version of the electronic pain questionnaire for school-aged children. Methods Primary (n = 79) and lower secondary (n = 127) schoolchildren aged 10-15 years from two schools from the Jyväskylä region of Finland, filled in an electronic questionnaire twice in an interval of 2 weeks. It captured the frequency of pain symptoms with a five-point Likert-scale questionnaire covering nine areas of the body for the last 3 months. The intraclass correlation coefficient (ICC) values 0.40-0.59 reflected fair and 0.60-0.74 good repeatability. Results The highest prevalences of pain were in the head (29%) and neck and shoulder (NS) (23%) areas. ICC values showed good repeatability for questions about pain frequency in the head, NS and lower extremities. In primary school, these values were good in the lower extremities and fair in NS, lower back and the head. In lower secondary school, the ICC values were good in NS and the head, fair in the stomach and lower extremities. Conclusions This electronic questionnaire was an acceptably repeatable indicator to measure the frequency of pain in the most prevalent pain areas: the head and NS. Implications It is important to be aware of the impact of health-related outcomes on children's ability to be successful in their lives. With the help of a simple electronic questionnaire, it is possible to cost-effectively capture, for example, the prevalence and frequency of pain during the school hours. The identification of children's pain symptoms accurately provides more possibilities to prevent and to minimize the chronic pain among schoolchildren. AD - Faculty of Sport and Health Science, University of Jyväskylä, Seminaarinkatu 15, Jyväskylän Yliopisto 40014, Finland. LIKES Research Centre for Physical Activity and Health, Jyväskylä, Finland. AN - 30917106 AU - Pirnes, K. P. AU - Kallio, J. AU - Siekkinen, K. AU - Hakonen, H. AU - Häkkinen, A. AU - Tammelin, T. DA - Jul 26 DO - 10.1515/sjpain-2018-0338 DP - NLM ET - 2019/03/28 IS - 3 KW - Adolescent Child Chronic Pain/*psychology Female Finland Head Humans Internet Male Neck Reproducibility of Results *Schools Shoulder *Surveys and Questionnaires *children *pain *questionnaire *repeatability LA - eng N1 - 1877-8879 Pirnes, Katariina P Kallio, Jouni Siekkinen, Kirsti Hakonen, Harto Häkkinen, Arja Tammelin, Tuija Journal Article Research Support, Non-U.S. Gov't Germany Scand J Pain. 2019 Jul 26;19(3):575-582. doi: 10.1515/sjpain-2018-0338. PY - 2019 SN - 1877-8860 SP - 575-582 ST - Test-retest repeatability of questionnaire for pain symptoms for school children aged 10-15 years T2 - Scand J Pain TI - Test-retest repeatability of questionnaire for pain symptoms for school children aged 10-15 years VL - 19 ID - 3011 ER - TY - JOUR AB - Anxiety and fear are determinants of acute and chronic pain. Effectively measuring fear associated with pain is critical for identifying individuals' vulnerable to pain. This study aimed to assess fear of pain among students and evaluate factors associated with pain-related fear. We used the Fear of Pain Questionnaire-9 to measure this fear. We searched for factors associated with fear of pain: gender, size of the city where the subjects lived, subject of academic study, year of study, the greatest extent of experienced pain, frequency of painkiller use, presence of chronic or mental illness, and past hospitalization. We enrolled 717 participants. Median fear of minor pain was 5 (4-7) fear of medical pain 7 (5-9), fear of severe pain 10 (8-12), and overall fear of pain 22 (19-26). Fear of pain was associated with gender, frequency of painkiller use, and previously experienced pain intensity. We found a correlation between the greatest pain the participant can remember and fear of minor pain (r = 0.112), fear of medical pain (r = 0.116), and overall fear of pain (r = 0.133). Participants studying medicine had the lowest fear of minor pain while stomatology students had the lowest fear of medical pain. As students advanced in their studies, their fear of medical pain lowered. Addressing fear of pain according to sex of the patient, frequency of painkiller use, and greatest extent of experienced pain could ameliorate medical training and improve the quality of pain management in patients. AD - II Department of Anesthesiology and Intensive Care, Medical University of Lublin, 20-081 Lublin, Poland. Student's Scientific Association, II Department of Anesthesiology and Intensive Care, Medical University of Lublin, 20-081 Lublin, Poland. AN - 33924523 AU - Piwowarczyk, P. AU - Kaczmarska, A. AU - Kutnik, P. AU - Hap, A. AU - Chajec, J. AU - Myśliwiec, U. AU - Czuczwar, M. AU - Borys, M. C2 - PMC8068817 DA - Apr 13 DO - 10.3390/ijerph18084098 DP - NLM ET - 2021/05/01 IS - 8 KW - *Anxiety/epidemiology Fear Humans Pain/epidemiology Students Surveys and Questionnaires *Universities *Fear of Pain Questionnaire *fear *gender *pain *painkillers LA - eng N1 - 1660-4601 Piwowarczyk, Paweł Orcid: 0000-0002-8529-484x Kaczmarska, Agnieszka Kutnik, Paweł Orcid: 0000-0002-8434-6812 Hap, Aleksandra Chajec, Joanna Myśliwiec, Urszula Czuczwar, Mirosław Borys, Michał Journal Article Int J Environ Res Public Health. 2021 Apr 13;18(8):4098. doi: 10.3390/ijerph18084098. PY - 2021 SN - 1661-7827 (Print) 1660-4601 ST - Association of Gender, Painkiller Use, and Experienced Pain with Pain-Related Fear and Anxiety among University Students According to the Fear of Pain Questionnaire-9 T2 - Int J Environ Res Public Health TI - Association of Gender, Painkiller Use, and Experienced Pain with Pain-Related Fear and Anxiety among University Students According to the Fear of Pain Questionnaire-9 VL - 18 ID - 3845 ER - TY - JOUR AB - Routine engagement in healthy behaviors may improve quality of life in older adults with chronic disabling conditions, such as multiple sclerosis (MS). However, older adults with chronic conditions may face many barriers to engaging in healthy behaviors. Health promotion and wellness services may help older adults with chronic conditions engage in healthy behaviors. Thus, the purpose of this study was to identify factors associated with the use of and unmet needs for heath promotion services among middle-aged and older adults with MS. Data from a cross-sectional telephone survey of individuals aging with MS in the mid-west USA were used for this study (n = 1282). A multinomial regression model was used to identify variables associated with the utilization of health promotion services. A logistic regression model was used to identify variables associated with unmet needs for these services. Females (OR = 1.51; CI: 1.13, 2.00), high school graduates (OR = 1.77; CI: 1.34, 2.34) and people who reported no problems with mobility or balance (OR = 1.68; CI: 1.12, 2.51) were more likely to utilize health promotion and wellness services. Factors that increased the likelihood of reporting an unmet need for these services were being female (OR = 2.34; CI: 1.56, 3.51), greater than a high school education (OR = 1.58; CI: 1.14, 2.20), not being married (OR = 1.79; CI: 1.31, 2.43), having inadequate income (OR = 1.83; CI: 1.31, 2.56), experiencing pain (OR = 1.96; CI: 1.34, 2.87) and reporting less ability to do everyday activities now compared with 1 year ago (OR = 2.13; CI: 1.16, 3.92). To avoid widening the health-disparities gap, future research needs to explore strategies that promote utilization of health promotion services among all middle-aged and older adults with MS. AD - Department of Occupational Therapy, University of Illinois at Chicago, Chicago, IL 60612, USA. mplow@uic.edu AN - 20427373 AU - Plow, M. AU - Cho, C. AU - Finlayson, M. DA - Sep DO - 10.1093/heapro/daq023 DP - NLM ET - 2010/04/30 IS - 3 KW - Age Factors Aged Cross-Sectional Studies Female Health Promotion/*organization & administration/*statistics & numerical data Healthcare Disparities/organization & administration Humans Male Middle Aged Midwestern United States Multiple Sclerosis/*therapy Patient Satisfaction Sex Factors Socioeconomic Factors LA - eng N1 - 1460-2245 Plow, Matthew Cho, Chi Finlayson, Marcia Journal Article Research Support, Non-U.S. Gov't England Health Promot Int. 2010 Sep;25(3):318-30. doi: 10.1093/heapro/daq023. Epub 2010 Apr 28. PY - 2010 SN - 0957-4824 SP - 318-30 ST - Utilization of health promotion and wellness services among middle-aged and older adults with multiple sclerosis in the mid-west US T2 - Health Promot Int TI - Utilization of health promotion and wellness services among middle-aged and older adults with multiple sclerosis in the mid-west US VL - 25 ID - 4120 ER - TY - JOUR AB - Background: The aim of this study was to analyse the psychometric properties of the Somatic Complaints List (SCL) in Spanish child and adult populations. This instrument assesses the frequency with which people experience and feel pain such as stomach ache and headache, among others. It has been validated in different countries and languages (Dutch, English, and Persian), showing adequate psychometric properties. Nevertheless, it has never been validated in a Spanish context. Method: For the adaptation and validation, we used two different samples: 1423 children, age ranging from 8 to 12 years old, selected from 12 primary and secondary schools at 7 locations in the Valencian Community, Spain (age = 9.11 years, SD = 1.27; 52.4% female); and 940 adults, age ranging from 18 to 56 years old (age = 32.3 years, SD = 11.62; 64% female). Results: The Spanish adaptation of the SLC showed adequate levels of reliability and validity. Conclusions: The empirical evidence seems sufficient to justify using this diagnostic tool with Spanish children and adults. AN - WOS:000358187900010 AU - Plumed, A. B. G. AU - Prado-Gasco, V. J. AU - Badenes, L. V. AU - Barron, R. G. DA - Aug DO - 10.7334/psicothema2015.8 IS - 3 N1 - Gorriz Plumed, Ana Belen Javier Prado-Gasco, Vicente Villanueva Badenes, Lidon Gonzalez Barron, Remedios Prado-gasco, vicente/k-7276-2014 PRADO-GASCO, VICENTE/0000-0002-2108-2186; Villanueva, Lidon/0000-0002-9006-159X 1886-144x PY - 2015 SN - 0214-9915 SP - 269-276 ST - Psychometric properties of the Somatic Complaints Scale in Spanish children and adults T2 - Psicothema TI - Psychometric properties of the Somatic Complaints Scale in Spanish children and adults UR - ://WOS:000358187900010 VL - 27 ID - 2226 ER - TY - JOUR AB - Background: There is concern that medical marijuana laws (MMLs) could negatively affect adolescents. To better understand these policies, we assess how adolescent exposure to MMLs is related to educational attainment. Methods: Data from the 2000 Census and 2001-2014 American Community Surveys were restricted to individuals who were of high school age (14-18) between 1990 and 2012 (n = 5,483,715). MML exposure was coded as: (i) a dichotomous "any MML" indicator, and (ii) number of years of high school age exposure. We used logistic regression to model whether MMLs affected: (a) completing high school by age 19; (b) beginning college, irrespective of completion; and (c) obtaining any degree after beginning college. A similar dataset based on the Youth Risk Behavior Survey (YRBS) was also constructed for confirmatory analyses assessing marijuana use. Results: MMLs were associated with a 0.40 percentage point increase in the probability of not earning a high school diploma or GED after completing the 12th grade (from 3.99% to 4.39%). High school MML exposure was also associated with a 1.84 and 0.85 percentage point increase in the probability of college non-enrollment and degree non-completion, respectively (from 31.12% to 32.96% and 45.30% to 46.15%, respectively). Years of MML exposure exhibited a consistent dose response relationship for all outcomes. MMLs were also associated with 0.85 percentage point increase in daily marijuana use among 12th graders (up from 1.26%). Conclusions: Medical marijuana law exposure between age 14 to 18 likely has a delayed effect on use and education that persists over time. (C) 2016 Elsevier Ireland Ltd. All rights reserved. AN - WOS:000387523800042 AU - Plunk, A. D. AU - Agrawal, A. AU - Harrell, P. T. AU - Tate, W. F. AU - Will, K. E. AU - Mellord, J. M. AU - Grucza, R. A. DA - Nov DO - 10.1016/j.drugalcdep.2016.09.002 N1 - Plunk, Andrew D. Agrawal, Arpana Harrell, Paul T. Tate, William F. Will, Kelli England Mellord, Jennifer M. Grucza, Richard A. Harrell, Paul/0000-0001-6588-7878 1879-0046 PY - 2016 SN - 0376-8716 SP - 320-327 ST - The impact of adolescent exposure to medical marijuana laws on high school completion, college enrollment and college degree completion T2 - Drug and Alcohol Dependence TI - The impact of adolescent exposure to medical marijuana laws on high school completion, college enrollment and college degree completion UR - ://WOS:000387523800042 VL - 168 ID - 2136 ER - TY - JOUR AB - BACKGROUND: Endometriosis-related pain symptoms have a negative impact on health-related quality of life and productivity. In fact, as endometriosis-related symptom severity and the number of symptoms experienced increases, health-related quality of life decreases. Dysmenorrhea and nonmenstrual pelvic pain are prominent symptoms experienced by women with endometriosis and were shown to have improved with the oral, nonpeptide gonadotropin-releasing hormone antagonist, elagolix. OBJECTIVE: The objective of this post hoc analysis was to address the question of if patients show a clinical response (in dysmenorrhea or nonmenstrual pelvic pain), do they also have improvements in health-related quality of life and in productivity? STUDY DESIGN: This post hoc analysis used data from the Elaris Endometriosis-I and Elaris Endometriosis-II phase III, randomized, placebo-controlled studies. A surgical diagnosis of endometriosis (in the past 10 years), premenopausal, aged 18-49 years, and moderate to severe endometriosis-associated pain were among the inclusion criteria for both trials. Women self-reported pain daily using a scale ranging from 0 (no pain) to 3 (severe pain); daily pain was assigned to either dysmenorrhea or nonmenstrual pelvic pain based on self-reported bleeding on that particular day. In addition, their self-reported endometriosis-associated pain must have been an average of moderate or severe during the month leading to baseline for inclusion in the trial program. Patients were characterized as achieving a clinical response for dysmenorrhea or nonmenstrual pelvic pain (ie, responder or nonresponder), which was defined as women who did not have an increase in analgesic use and who met the pain reduction score threshold at month 3. Pain reduction score thresholds were defined separately for dysmenorrhea and nonmenstrual pelvic pain in the trial using receiver-operating characteristics analysis. Health-related quality of life was assessed using the Endometriosis Health Profile-30; work productivity was assessed using the Health-Related Productivity Questionnaire. RESULTS: Women enrolled in Elaris Endometriosis-I (n = 871) and Elaris Endometriosis-II (n = 815) were included in this analysis. Patients with a clinical response during treatment to dysmenorrhea or nonmenstrual pelvic pain also experienced a meaningful improvement in all domains of the Endometriosis Health Profile-30 at month 3. Patients who did not show a dysmenorrhea or nonmenstrual pelvic pain clinical response at month 3 did not exhibit mean improvements in Endometriosis Health Profile-30 domain scores that indicate an Endometriosis Health Profile-30 responder. Productivity improved among dysmenorrhea clinical responders. In the Elaris Endometriosis-I study, clinical responders lost a total of 5.9 hours compared with a total of 13.0 hours for nonresponders of employment-related work at month 3 (P < .0001). Among women in the Elaris Endometriosis-II study, a total of 4.1 hours and 10.4 employment-related hours were lost at month 3 for dysmenorrhea responders vs nonresponders (P < .001). Similar results were obtained when analyzed by non-enstrual pelvic pain responder status. CONCLUSION: Women with moderate to severe endometriosis-related pain, who are clinical responders based on dysmenorrhea and nonmenstrual pelvic pain, also experience significant and clinically meaningful improvement in health-related quality of life and productivity as measured by the Endometriosis Health Profile-30 and Health-Related Productivity Questionnaire, respectively. AD - Patient-Centered Research, Evidera, Bethesda, MD. Electronic address: robin.pokrzywinski@evidera.com. AbbVie, Inc, North Chicago, IL. Patient-Centered Research, Evidera, Bethesda, MD. Colorado Center for Reproductive Medicine, Lone Tree, CO. Yale School of Medicine, New Haven, CT. AN - 31759891 AU - Pokrzywinski, R. M. AU - Soliman, A. M. AU - Chen, J. AU - Snabes, M. C. AU - Coyne, K. S. AU - Surrey, E. S. AU - Taylor, H. S. DA - Jun DO - 10.1016/j.ajog.2019.11.1255 DP - NLM ET - 2019/11/25 IS - 6 KW - Adolescent Adult Dysmenorrhea/*drug therapy *Efficiency Endometriosis/*drug therapy Female Gonadotropin-Releasing Hormone/antagonists & inhibitors Hormone Antagonists/*therapeutic use Humans Hydrocarbons, Fluorinated/*therapeutic use Middle Aged Pelvic Pain/*drug therapy Pyrimidines/*therapeutic use *Quality of Life Treatment Outcome *Work Young Adult *Endometriosis Health Profile-30 *Health-Related Productivity Questionnaire *absenteeism *endometriosis *health-related quality of life LA - eng N1 - 1097-6868 Pokrzywinski, Robin M Soliman, Ahmed M Chen, Jun Snabes, Michael C Coyne, Karin S Surrey, Eric S Taylor, Hugh S Clinical Trial, Phase III Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't United States Am J Obstet Gynecol. 2020 Jun;222(6):592.e1-592.e10. doi: 10.1016/j.ajog.2019.11.1255. Epub 2019 Nov 22. PY - 2020 SN - 0002-9378 SP - 592.e1-592.e10 ST - Achieving clinically meaningful response in endometriosis pain symptoms is associated with improvements in health-related quality of life and work productivity: analysis of 2 phase III clinical trials T2 - Am J Obstet Gynecol TI - Achieving clinically meaningful response in endometriosis pain symptoms is associated with improvements in health-related quality of life and work productivity: analysis of 2 phase III clinical trials VL - 222 ID - 4181 ER - TY - JOUR AB - Background: Sickle Cell Disease is the commonest monogenic haemoglobinopathy worldwide. Living with a long-term condition such as sickle cell disease during adolescence constitutes a significant challenge for the key stakeholders due to the combined effects of chronic illness and adolescent development. For adolescents with sickle cell disease to be cared for and supported appropriately and effectively, it is crucial that health professionals have a comprehensive knowledge and understanding of how adolescents experience living with the condition. While there is developing literature about how adolescent's experience sickle cell disease, this body of research has not been critically reviewed and synthesised. Objective: To identify, critically appraise and synthesise primary research exploring adolescents' experiences of living with sickle cell disease to make recommendations for practice and research. Design: Integrative narrative review. Data sources: A systematic search of 10 electronic databases and key journals was conducted to identify studies from the inception of databases to September 2016. Review method: Inclusion criteria: adolescents with sickle cell disease aged 12-19 years, primary data on adolescents' own perspectives, and published in English. Data were extracted on study contexts, methodology/design, theoretical constructs, participants, and key findings. Findings from included studies were synthesised using the integrative narrative approach. Additionally, the methodological quality of studies was assessed using the Hawker et al. (2002) appraisal checklist. Results: 683 studies were identified, of which 40 fulfilled the inclusion criteria. Nine broad themes emerged: knowledge and understanding of the condition, symptom experiences, self-management, attitude to treatment, healthcare experiences, social relationships, difference and striving for normality, school experiences, and emotional well-being and coping. Majority of the studies were of moderate quality methodologically. Quality assessment demonstrated a high risk of bias in three studies. Conclusions: Sickle cell disease impacts on multiple facets of an adolescent's life. While there are similarities in the experience of living with sickle cell disease and living with other chronic illnesses, there are essential differences in relationship dynamics and healthcare experience. The adolescents expressed less confidence in generic healthcare providers. The review highlights areas relating to symptom management and health service provision that has been under-researched and need further exploration to understand adolescents' experiences and their support needs fully. Nursing care and research should focus more on adolescents' developmental wellbeing, promote peer support network among adolescents with the condition and with adolescents with other chronic illnesses and collaborate with adolescents to ensure service development are developmentally and culturally appropriate. AN - WOS:000430784600003 AU - Poku, B. A. AU - Caress, A. L. AU - Kirk, S. DA - Apr DO - 10.1016/j.ijnurstu.2017.12.008 N1 - Poku, Brenda Agyeiwaa Caress, Ann-Louise Kirk, Susan Poku, Brenda/0000-0002-2265-7041 1873-491x PY - 2017 SN - 0020-7489 SP - 20-28 ST - Adolescents' experiences of living with sickle cell disease: An integrative narrative review of the literature T2 - International Journal of Nursing Studies TI - Adolescents' experiences of living with sickle cell disease: An integrative narrative review of the literature UR - ://WOS:000430784600003 VL - 80 ID - 2102 ER - TY - JOUR AB - Background: Headache is the most common painful manifestation in the developmental age, often accompanied by severe disability such as scholastic absenteeism, low quality of academic performance and compromised emotional functioning. The aim of the study is to evaluate praxis abilities in a population of children without aural migraine. Materials and methods: The test population consists of 10 subjects without migraine without aura (MwA), (8 Males) (mean age 8.40, SD +/- 1.17) and 11 healthy children (7 Males) (mean age 8.27; SD +/- 1.10; p = 0.800). All subjects underwent evaluation of motor coordination skills through the Battery for Children Movement Assessment (MABC). Results: The two groups (10 MwA vs 11 Controls) were similar for age (8.40 +/- 1.17 vs 8.27 +/- 1.10; p = 0.800), sex (p = 0. 730), and BMI (p = 0.204). The migraine subjects show an average worse performance than the Movement ABC; specifically, migraineurs show significantly higher total score values (31.00 +/- 23.65 vs 4.72 +/- 2.61; p = 0.001), manual dexterity (12.10 +/- 11.20 vs 2.04 +/- 2.65; p = 0.009) and balance (14.85 +/- 10.08 vs. 1.04 +/- 1.05; p <0.001). The mean percentile of migraine performance is significantly reduced compared to controls (9.00 +/- 3.82 vs 51.00 +/- 24.34, p <0.001) (Table 1). Conclusion: Migraine can alter many cognitive and executive functions such as motor skills in developmental age. AN - WOS:000450232900009 AU - Polito, A. N. AU - Picciocchi, E. AU - Geraci, D. AU - Chisari, M. G. AU - Marsala, G. AU - Sorrentino, M. AU - Tripi, G. AU - Salerno, M. AU - Russo, D. AU - Lavano, S. M. AU - Cerroni, F. AU - Romano, P. AU - Marotta, R. AU - Lavano, F. AU - Magliulo, R. M. AU - D'Oro, L. AU - Di Folco, A. AU - Parisi, L. AU - Testa, D. AU - Murabito, P. AU - Salerno, M. AU - Gallai, B. DO - 10.19193/0393-6384_2018_4s_329 N1 - Polito, Anna Nunzia Picciocchi, Elisabetta Geraci, Diego Chisari, Mario Giuseppe Marsala, Gabriella Sorrentino, Michele Tripi, Gabriele Salerno, Margherita Russo, Daniela Lavano, Serena Marianna Cerroni, Francesco Romano, Palmira Marotta, Rosa Lavano, Francesco Magliulo, Rosaria Martina D'Oro, Lucrezia Di Folco, Annabella Parisi, Lucia Testa, Davide Murabito, Paolo Salerno, Monica Gallai, Beatrice SALERNO, MONICA/AAC-1321-2019; Marotta, Rosa/AAG-1453-2020 SALERNO, MONICA/0000-0002-6410-3960; Marotta, Rosa/0000-0003-0515-5952; Murabito, Paolo/0000-0002-2662-1898 2283-9720 4 PY - 2018 SN - 0393-6384 SP - 2143-2150 ST - MOTOR SKILLS IN CHILDREN WITH PRIMARY HEADACHE: A PILOT CASE-CONTROL STUDY T2 - Acta Medica Mediterranea TI - MOTOR SKILLS IN CHILDREN WITH PRIMARY HEADACHE: A PILOT CASE-CONTROL STUDY UR - ://WOS:000450232900009 VL - 34 ID - 2045 ER - TY - JOUR AB - We showed the data on clinical efficiency of low doses of antibodies to brain-specific protein S100 in the complex therapy of schoolchildren with painful variant of functional dyspepsia syndrome. Significant positive effects of the substance on the dynamics of epigastric pain, in particular, its duration, were found. The maximum clinical effect was observed in children with emotional disorders ( of all examined children). Along with significant decrease in frequency appearance and duration of pain syndrome, the substance also normalized emotional state and improved attention concentration in children. AN - WOS:000359428000013 AU - Polivanova, T. V. AU - Smirnova, O. V. AU - Gorbacheva, N. N. AU - Vshivkov, V. A. DA - Jul DO - 10.1007/s10517-015-2957-y IS - 3 N1 - Polivanova, T. V. Smirnova, O. V. Gorbacheva, N. N. Vshivkov, V. A. Smirnova, Olga/C-2722-2018; Polivanova, Tamara/E-6159-2015; Vshivkov, Vitaliy/E-6164-2015 Smirnova, Olga/0000-0003-3992-9207; Polivanova, Tamara/0000-0003-3842-9147; Vshivkov, Vitaliy/0000-0002-1410-8747 1573-8221 PY - 2015 SN - 0007-4888 SP - 341-343 ST - Effi ciency of Very Low Doses of Antibodies to S100 Protein in the Complex Therapy of Functional Dyspepsia in Children T2 - Bulletin of Experimental Biology and Medicine TI - Effi ciency of Very Low Doses of Antibodies to S100 Protein in the Complex Therapy of Functional Dyspepsia in Children UR - ://WOS:000359428000013 VL - 159 ID - 2227 ER - TY - JOUR AB - Objectives: Abdominal pain-related pediatric functional gastrointestinal disorders (AP-FGIDs) are defined by abdominal discomfort or pain that may provide obstacles to everyday activities, such as school attendance. It has been reported that AP-FGID symptoms may be reduced in summer, but it is unclear what drives this seasonal variation. This pilot study aimed to explore whether the seasonal variation in AP-FGID symptoms could be explained by various psychological and behavioral factors. Methods: Parents of children with AP-FGID symptoms completed online questionnaires on symptoms, anxiety, parental responses to pain, sleep, diet, and physical activity once during spring months and again in the summer months. Results: In a sample of 34 participants who completed both questionnaires, 22 reported improvements during the summer months. These participants reported a significantly higher seasonal decrease in anxiety than participants whose children's symptoms did not improve from spring to summer (mean decrease 2.21 vs 0.08, P = 0.017). Both groups reported equal improvements in sleep and decreased stress from spring to summer. Neither group experienced statistically significant seasonal change in physical activity or fruit, vegetables, dairy, or caffeine consumption. Conclusions: This study suggests that amelioration of gastrointestinal symptoms in pediatric patients with AP-FGID during summer months is associated with amelioration of anxiety in the same time period. It is not yet clear whether decreased anxiety is the cause or effect of decreased AP-FGID symptoms. AN - WOS:000441421500012 AU - Pollard, K. L. AU - Campbell, C. AU - Squires, M. AU - Palsson, O. AU - van Tilburg, M. A. L. DA - Jul DO - 10.1097/mpg.0000000000001886 IS - 1 N1 - Pollard, Katharine L. Campbell, Christina Squires, Megan Palsson, Olafur van Tilburg, Miranda A. L. van tilburg, miranda/0000-0002-0504-9829 1536-4801 PY - 2018 SN - 0277-2116 SP - 18-22 ST - Seasonal Association of Pediatric Functional Abdominal Pain Disorders and Anxiety T2 - Journal of Pediatric Gastroenterology and Nutrition TI - Seasonal Association of Pediatric Functional Abdominal Pain Disorders and Anxiety UR - ://WOS:000441421500012 VL - 67 ID - 2005 ER - TY - JOUR AB - Objectives: Lumbar punctures (LPs) are painful for children, and analgesia is recommended by academic societies. However, less than one-third of pediatric emergency physicians (EPs) adhere to recommendations. We assessed the willingness to provide analgesia among pediatric and general EPs and explored patient and provider-specific barriers. Methods: We surveyed physicians in the Pediatric Emergency Research Canada (PERC) or Canadian Association of Emergency Physicians (CAEP) databases from May 1 to August 1, 2016, regarding hypothetical scenarios for a 3-week-old infant, a 3-year-old child, and a 16-year-old child requiring an LP. The primary outcome was the willingness to provide analgesia. Secondary outcomes included the type of analgesia, reasons for withholding analgesia, and their perceived competence performing LPs. Results: For a 3-week old infant, 123/144 (85.4%) pediatric EPs and 231/262 (88.2%) general EPs reported a willingness to provide analgesia. In contrast, the willingness to provide analgesia was almost universal for a 16-year-old (144/144 [100%] of pediatric EPs and 261/262 [99.6%] of general EPs) and a 3-year-old (142/144 [98.6%] of pediatric EPs and 256/262 [97.7%] of general EPs). For an infant, the most common barrier cited by pediatric EPs was the perception that it produced additional discomfort (13/21, 61.9%). The same reason was cited by general EPs (12/31, 38.7%), along with unfamiliarity surrounding analgesic options (13/31, 41.9%). Conclusion: Compared to a preschool child and adolescent, the willingness to provide analgesia for an LP in a young infant is suboptimal among pediatric and general EPs. Misconceptions and the lack of awareness of analgesic options should be targets for practice-changing strategies. AN - WOS:000462666700012 AU - Poonai, N. AU - Brzozowski, V. AU - Stang, A. S. AU - Drendel, A. L. AU - Boisclair, P. AU - Miller, M. AU - Harman, S. AU - Ali, S. AU - Pediat Emergency Res Canada, Perc DA - Mar DO - 10.1017/cem.2018.382 IS - 2 N1 - Poonai, Naveen Brzozowski, Victoria Stang, Antonia S. Drendel, Amy L. Boisclair, Philippe Miller, Michael Harman, Stuart Ali, Samina 1481-8043 PY - 2019 SN - 1481-8035 SP - 199-203 ST - Pain management practices surrounding lumbar punctures in children: A survey of Canadian emergency physicians T2 - Canadian Journal of Emergency Medicine TI - Pain management practices surrounding lumbar punctures in children: A survey of Canadian emergency physicians UR - ://WOS:000462666700012 VL - 21 ID - 1942 ER - TY - JOUR AB - (Full text is available at http://www.manu.edu.mk/prilozi). The research concerned a group of 59 children, 22 girls and 37 boys, mean age 12.5 +/- 1.24 years, with tension type headaches. Their clinical results (neurological, neuropsychological, radiological and laboratory) were normal, suggesting psychosomatic etiology. The characteristics of the headache correspond to a nosologic entity known as tension-type headache. The aim of this study was to evaluate the psychological characteristics of these children and their families, especially the profile of the mothers. The psychological assessment, consecutively applied, comprised: Eysenck Personality Questionnaire (EPQ), Emotions Profile Index (EPI), General Anxiety State (GAS) and Human Values Rank (HVR). The mothers were examined by Family Inventory Life Events (FILE) and Minnesota Multiphasic Personality Inventory (MMPI) and also checked with the Child Behavior Check List (CBCL). The results obtained showed a non-negligible level of actual anxiety in all the children, who were mostly the first-born and lived in families with accentuated stress. The emotional profile of the children was characterized by impulsiveness, a feeling of fear, moderate aggression, but still with a great level of acceptability. The EPQ confirmed their extroversion, moderate neurotic manifestations and a need for social acceptance. These results suggest that in preadolescents emotional stress, combined with a "model" for somatization, could provoke specific involuntary contraction of the head and neck muscles causing local ischaemia, which may be the pathophysiologic cause of a tension-type headache. The therapy comprised EDR and EMG biofeedback, applied once per week, of 50-minute duration. The results obtained after 20 sessions are very satisfactory. In addition, some response-measures involving a change and adjustment of family relations and school environment are recommended. Key words: headache, children, biofeedback, psychophysiology. AD - Paediatric clinic, Faculty of Medicine, University of Skopje, R. Macedonia. npopjordanova@gmail.com AN - 19736538 AU - Pop-Jordanova, N. AU - Zorcec, T. DA - Jul DP - NLM ET - 2009/09/09 IS - 1 KW - *Biofeedback, Psychology Child Electromyography Female Humans Mmpi Male Mothers/psychology Personality Assessment Psychological Tests Tension-Type Headache/*psychology/therapy LA - eng N1 - Pop-Jordanova, N Zorcec, T Journal Article Germany Prilozi. 2009 Jul;30(1):155-66. PY - 2009 SN - 0351-3254 (Print) 0351-3254 SP - 155-66 ST - Psychological assessment and biofeedback mitigation of tension-type headaches in children T2 - Prilozi TI - Psychological assessment and biofeedback mitigation of tension-type headaches in children VL - 30 ID - 3495 ER - TY - JOUR AB - A cross-sectional telephone survey was conducted in nationally representative probability sample of non-Hispanic white subjects, non-Hispanic African American subjects, and Hispanic subjects of any race to explore relationships between chronic pain and race or ethnicity. Approximately one third in each group reported "frequent or persistent pain" for 3 months or longer during the past year, and approximately one third of the 454 white subjects, 447 African American subjects, and 434 Hispanic subjects in the final sample experienced "disabling pain" (defined as both high severity and high functional interference). White subjects had pain longer but with lesser intensity than the other groups, and pain-related life interference did not vary. Significantly fewer Hispanic subjects (68%) than white subjects (82%) or African American subjects (85%) had visited a physician for pain, and African American subjects (81%) were more likely than white subjects (75%) or Hispanic subjects (63%) to have used prescription medications. Disabling pain was positively associated with female sex (odds ratio [OR], 1.45), income of $25,000 or less (OR, 1.71), less than a high school education (OR, 1.72), and divorce (OR, 1.69) and was negatively associated with younger age (18-34 years; OR, 0.68), income between $25,000 and $74,999 (OR, 0.64) or $75,000 or more (OR, 0.37), being employed (OR, 0.48), suburban residence (OR, 0.64), and having a college (OR, 0.51) or graduate (OR, 0.32) degree. Multivariate logistic regression found that income of $25,000 or less (OR, 2.54), less than a high school education (OR, 1.59), and being unemployed (OR, 1.50) remained significant when other factors were controlled. Neither race nor ethnicity predicted disabling pain, but the minorities had more characteristics identified as predictors. The data suggest that race and ethnicity contribute to clinical diversity, but socioeconomic disadvantage is the more important predictor of disabling pain. PERSPECTIVE: Race and ethnicity influence the presentation and treatment of chronic pain. This study evaluated community-dwelling white, African American, and Hispanic subjects by using a sophisticated telephone survey methodology. Pain was highly prevalent across groups, and there were racial and ethnic differences in pain experience and treatment preferences. Race and ethnicity were not independently associated with severe pain, but both minorities were more likely to possess the socioeconomic and educational characteristics that were associated. AD - Department of Pain Medicine and Palliative Care, Beth Israel Medical Center, New York, NY 10003, USA. RPortenoy@bethisraelny.org AN - 15336636 AU - Portenoy, R. K. AU - Ugarte, C. AU - Fuller, I. AU - Haas, G. DA - Aug DO - 10.1016/j.jpain.2004.05.005 DP - NLM ET - 2004/09/01 IS - 6 KW - Adolescent Adult African Americans/*psychology Confidence Intervals Cross-Sectional Studies European Continental Ancestry Group/*psychology Female Hispanic Americans/*psychology Humans Linear Models Male Middle Aged Multivariate Analysis Odds Ratio Pain/*ethnology/*psychology Pain Measurement/*psychology Socioeconomic Factors United States/ethnology LA - eng N1 - Portenoy, Russell K Ugarte, Carlos Fuller, Ivonne Haas, Gregory Comparative Study Journal Article Research Support, Non-U.S. Gov't United States J Pain. 2004 Aug;5(6):317-28. doi: 10.1016/j.jpain.2004.05.005. PY - 2004 SN - 1526-5900 (Print) 1526-5900 SP - 317-28 ST - Population-based survey of pain in the United States: differences among white, African American, and Hispanic subjects T2 - J Pain TI - Population-based survey of pain in the United States: differences among white, African American, and Hispanic subjects VL - 5 ID - 4018 ER - TY - JOUR AB - Background: Pain in the cervical spine area is one of the main health problems of inhabitants of Western Europe. The necessity of parents' taking care of a child with physical disability is connected with parents' exposure to the factors affecting the risk of occurrence of pain in the cervical spine. Objective: The objective of this study was to analyze whether there are differences in the occurrence of cervical spine pain between the group of parents of children with physical disability and parents of children without a disability. Method: The research included a group of parents of school-aged children with physical disability (n = 47) and a group of parents of children without disability (n = 69), aged between 29 and 60 years from the Silesian Voivodeship (Poland). The people taking part in the research were asked to complete two questionnaires: Visual Analogue Scale (VAS) for the cervical spine and Neck Disability Index (NDI) questionnaire. Means, standard deviations, and ranges to compare scores across groups were calculated. Results: The mean VAS score among parents of children with physical disability was 4.22 (SD = 3.23) compared to 2.16 (SD = 2.31; p < .001) among parents of children without physical disability. Similarly, mean NDI scores were 19.6 (SD = 15.12) and 9.68 (SD = 8.84; p < .001), respectively. Conclusions: The parents of children with physical disability are to a greater extent exposed to the occurrence of cervical spine pain. Therefore, suitable training as regards ergonomics, especially during lifting, transferring and transporting children might be beneficial to these parents. (C) 2015 Elsevier Inc. All rights reserved. AN - WOS:000351313400017 AU - Posluszny, A. AU - Mysliwiec, A. AU - Saulicz, E. AU - Doroniewicz, I. AU - Linek, P. AU - Wolny, T. DA - Apr DO - 10.1016/j.dhjo.2014.09.008 IS - 2 N1 - Posluszny, Adam Mysliwiec, Andrzej Saulicz, Edward Doroniewicz, Iwona Linek, Pawel Wolny, Tomasz Saulicz, Edward/X-3021-2018; Linek, Pawel/W-9630-2018; Wolny, Tomasz/W-8348-2018; Linek, Pawel/S-8066-2019 Saulicz, Edward/0000-0001-6596-3770; Linek, Pawel/0000-0002-8542-8123; Wolny, Tomasz/0000-0001-7910-757X; Linek, Pawel/0000-0002-8542-8123; Doroniewicz, Iwona/0000-0002-3740-5461 1876-7583 PY - 2015 SN - 1936-6574 SP - 278-283 ST - The occurrence of the cervical pain syndromes in parents of children with physical disability in the population of Poland T2 - Disability and Health Journal TI - The occurrence of the cervical pain syndromes in parents of children with physical disability in the population of Poland UR - ://WOS:000351313400017 VL - 8 ID - 2240 ER - TY - JOUR AB - During the past 30 years, the prevalence of headache in children in the western world has significantly increased. Although food intolerance is a well known factor influencing headache in children, the dimensions of this have not been clearly evaluated yet. Severe migraine in children can be mitigated by strict dietary treatment in about 90 % of the cases. But in the longterm, such strict dietary regimes - especially according to Chinese medicine - are hardly practicable. Thus, a simplified nutritional change seems to be more appropriate in order to achieve a long-lasting influence on school children`s headache. Methods: Therefore, a randomized study was started to investigate the efficacy of a longer lasting nutritional intervention in children with headache, comparing the effects of a self-help brochure to those of individual nutritional advice. Children (7-18 years) with migraine, tension-type headache or a combination of both were randomized into two groups: "self-help program with a brochure" or "individual nutritional advice". Nutritional change according to Traditional Chinese Medicine as well as state of the art in modern nutritional chemistry included avoidance of milk, curd cheese, wheat flour, white sugar, chocolate, preservatives, coloring and other food additives. After 12 weeks of nutritional change, mitigation of headache was checked in a control appointment. A reduction of headache frequency and intensity in the range of 50 % or more as revealed in headache calendars was defined as success. Results: Out of 117 randomized participants, 32 (27 %) suffered from lactose malabsorption. 25 patients failed to fulfil the introduction criteria or broke off, showing a slightly higher but not significant dropout rate in the self-help group. 76 of the remaining participants changed their nutritional habits. 59 (83 %) reported subjective improvement, 56 of which fulfilled the success criteria with no statistically significant difference between the two groups. No significant difference was found between tension type headache and migraine. Conclusion: Not only migraine but also tension-type headache responded in a relevant dimension to nutritional treatment. In case of higher migraine frequency combined with allergic comorbidity the efficacy of the nutritional regime seems to be even more pronounced. Personal counseling shows only a trend towards better clinical results. The lacking statistical difference between the two treatment groups excludes a significant importance of personal influence as explanation of headache improvement. In daily counselling, a combination of written information and a short personal explanation seems to be a practicable procedure. AN - WOS:000421602900006 AU - Pothmann, R. DO - 10.1016/j.dza.2011.01.013 IS - 1 N1 - Pothmann, R. 1439-4359 PY - 2011 SN - 0415-6412 SP - 25-29 ST - Dietetic Treatment of Headache in Children T2 - Deutsche Zeitschrift Fur Akupunktur TI - Dietetic Treatment of Headache in Children UR - ://WOS:000421602900006 VL - 54 ID - 2516 ER - TY - JOUR AB - The prevalence of functional headaches in schoolchildren is high. Some of these headaches could be triggered by impaired function of the upper two cervical vertebrae. Thus manual therapy could be an effective approach. A self-help home program was therefore compared with a one-off manual therapy session. In total, 67 children (aged 6-17 years) were investigated and treated. Inclusion criterions were at least one incidence of headache per week over a period of 30 consecutive days and a confirmed impairment to upper cervical spine movement. The children were randomized to two therapeutic groups: one group performed relaxation and distraction exercises, the other underwent a special, one-off manual intervention. Headaches per day, duration and intensity of headaches, analgesic use, missed leisure activities and school absences were documented 30 days before and after treatment. A highly significant reduction in headaches could be shown for both treatment methods at the time of follow-up. Although there was no statistically relevant difference between the two methods, manual therapy showed a small trend toward better response. The other parameters also showed a significant improvement in both groups, but there was no statistical difference between the two methods. Measured in terms of the frequency of alternative treatment applications, one-off manual therapy appears to confer a benefit; however, it requires special treatment skills in the therapist. It can be helpful in some cases where standardised forms of treatment are not effective in the long term. AN - WOS:000429541600008 AU - Pothmann, R. AU - Koch, L. E. AU - Wiegand, G. AU - Graumann-Brunt, S. DA - Apr DO - 10.1007/s00337-017-0365-2 IS - 2 N1 - Pothmann, Raymund Koch, Lutz Erik Wiegand, Gert Graumann-Brunt, S. 1433-0466 PY - 2018 SN - 0025-2514 SP - 162-169 ST - Headache in children with cervical components. Comparative study of one-off manual intervention and a self-help home program T2 - Manuelle Medizin TI - Headache in children with cervical components. Comparative study of one-off manual intervention and a self-help home program UR - ://WOS:000429541600008 VL - 56 ID - 2023 ER - TY - JOUR AB - This study was conducted to determine the following among a group of female university students: the prevalence of dysmenorrhea; pain severity ratings; methods used to manage dysmenorrhea; and the effect of dysmenorrhea on daily activities, school attendance, and ability to communicate with friends. This cross-sectional study was conducted between December 2009 and February 2010 at a public university located in Istanbul, in the northwest area of Turkey. The study group included 1515 female students. Data were collected from the female students in the study group using a self-report questionnaire; the severity of dysmenorrhea was determined with the visual analog scale. The data were examined with mean, percentages, chi-square analysis, and logistic regression. The prevalence of dysmenorrhea in the study group was 85.7%. Of this group of subjects with dysmenorrhea, 30.4% described their menstrual pain as severe, 49.8% as moderate, and 19.8% as mild. The mean severity of pain among the students was 6.33 +/- 2.32 on the VAS. The majority of participants who experienced moderate or severe pain regularly used analgesics for pain management, and participants who experienced severe pain used analgesics before the beginning of menstruation. Participants who experienced moderate pain used herbal tea, massage, heat application, rest, and distraction for pain management. Participants who experienced severe pain consulted a physician and that a significant difference existed between the dysmenorrhea rating groups in this regard (p < .001). Severe pain was significantly associated with school absenteeism and limitations in social activities/functioning (p < .001). Dysmenorrhea is highly prevalent among university students and is related to school absenteeism, ability to participate in and enjoy daily activities, and limitations in social activities/functioning. (C) 2014 by the American Society for Pain Management Nursing AN - WOS:000345429800008 AU - Potur, D. C. AU - Bilgin, N. C. AU - Komurcu, N. DA - Dec DO - 10.1016/j.pmn.2013.07.012 IS - 4 N1 - Potur, Dilek Coskuner Bilgin, Nevin Citak Komurcu, Nuran POTUR, DILEK COSKUNER/V-3824-2017; Bilgin, Nevin Citak/ABA-2616-2020 Coskuner potur, dilek/0000-0002-2186-4663 1532-8635 PY - 2014 SN - 1524-9042 SP - 768-777 ST - Prevalence of Dysmenorrhea in University Students in Turkey: Effect on Daily Activities and Evaluation of Different Pain Management Methods T2 - Pain Management Nursing TI - Prevalence of Dysmenorrhea in University Students in Turkey: Effect on Daily Activities and Evaluation of Different Pain Management Methods UR - ://WOS:000345429800008 VL - 15 ID - 2271 ER - TY - JOUR AB - Objectives To identify baseline patient characteristics that are (1) associated with a poor outcome on follow-up regardless of which treatment was provided (prognosis) or (2) associated with a successful outcome to a specific treatment (treatment effect modifiers). Design Systematic literature review according to Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. Data sources Medline, Embase, Cinahl, Web of Science, Cochrane, SportDiscus, OT Seeker and PsychInfo were searched for prospective cohort studies up to February 2019 without limitation in publication date. Eligibility criteria Prospective cohort studies reporting either prognostic factors or treatment effect modifiers on persistent musculoskeletal pain in 0-year-old to 19-year-old children and adolescents. Pain caused by tumours, fractures, infections, systemic and neurological conditions were excluded. Outcome measures Our primary outcome was musculoskeletal pain at follow-up and identification of any baseline characteristics that were associated with this outcome (prognostic factors). No secondary outcomes were declared. Method Two reviewers independently screened abstracts and titles. We included prospective cohort studies investigating the prognosis or treatment effect modifiers of 0-year-old to 19-year-old children and adolescents with self-reported musculoskeletal pain. Risk of bias assessment was conducted with the Quality in Prognostic Studies tool. Results Twenty-six studies yielding a total of 111 unique prognostic factors were included. Female sex and psychological symptoms were the most frequent investigated prognostic factors. Increasing age, generalised pain, longer pain duration and smoking were other identified prognostic factors. No treatment effect modifiers were identified. Conclusion Several prognostic factors are associated with a poor prognosis in children and adolescents with musculoskeletal pain. These prognostic factors may help guide clinical practice and shared decision-making. None of the included studies was conducted within a general practice setting which highlights an area in need of research. AN - WOS:000485269700185 AU - Pourbordbari, N. AU - Riis, A. AU - Jensen, M. B. AU - Olesen, J. L. AU - Rathleff, M. S. C7 - e024921 DA - Aug DO - 10.1136/bmjopen-2018-024921 IS - 7 N1 - Pourbordbari, Negar Riis, Allan Jensen, Martin Bach Olesen, Jens Lykkegaard Rathleff, Michael Skovdal Jensen, Martin Bach/0000-0003-2162-7390; Pourbordbari, Negar/0000-0002-1291-8324; Riis, Allan/0000-0002-7009-3025 PY - 2019 SN - 2044-6055 ST - Poor prognosis of child and adolescent musculoskeletal pain: a systematic literature review T2 - Bmj Open TI - Poor prognosis of child and adolescent musculoskeletal pain: a systematic literature review UR - ://WOS:000485269700185 VL - 9 ID - 1889 ER - TY - JOUR AB - Headache is a common condition among children and adolescents, and it can result in considerable pain, distress, and functional disability. Lacking proper care, many children will continue to experience headaches into adulthood. These considerations point to the importance of prompt, effective, and early intervention for pediatric headache. Biobehavioral treatments are central to such intervention. From promotion of adherence to optimal use of abortive and prophylactic medications to health behaviors that reduce headache activity to biofeedback-assisted relaxation training, the addition of biobehavioral treatment components to a comprehensive pediatric headache care plan can lead to better initial clinical outcomes, may lessen the need for medication, and may help maintain effects over the long term. Attention to the effects of headache and the accompanying psychological distress is an equally important part of treatment. Indeed, outcomes should be measured in terms of pain parameters (headache frequency, duration, severity) and effect on functional disability and quality of life (school absences, mood, satisfaction with pain relief). Optimal care for children and adolescents with headache can be realized with collaboration among primary care practitioners and headache specialists such as child neurologists and pediatric behavioral medicine experts. Biobehavioral treatment is a foundation for provision of such care. AD - Headache Center, Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, OH 45229-3039, USA. AN - 16018228 AU - Powers, S. W. AU - Andrasik, F. DA - Jun DO - 10.3928/0090-4481-20050601-11 DP - NLM ET - 2005/07/16 IS - 6 KW - Biofeedback, Psychology Child Headache/psychology/*therapy Humans Quality of Life Relaxation Therapy Treatment Outcome LA - eng N1 - Powers, Scott W Andrasik, Frank Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, P.H.S. Review United States Pediatr Ann. 2005 Jun;34(6):461-5. doi: 10.3928/0090-4481-20050601-11. PY - 2005 SN - 0090-4481 (Print) 0090-4481 SP - 461-5 ST - Biobehavioral treatment, disability, and psychological effects of pediatric headache T2 - Pediatr Ann TI - Biobehavioral treatment, disability, and psychological effects of pediatric headache VL - 34 ID - 3940 ER - TY - JOUR AB - BACKGROUND: Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder associated with stress, which may appear by an educational context, given that students are exposed to demands in the academic environment during their education process that may lead to developing diseases. This study reports on the relationship between the IBS and academic stress and compares results of men and women. METHODS: A random survey was made of 561 medicine students at a public university in Mexico. The ROMA III criteria were used for the IBS and the Academic Stress Inventory for academic stress. A multiple regression analysis was made. RESULTS: The results showed that students with academic overload and lack of time are at risk for developing the IBS. CONCLUSIONS: Therefore, the recommendation is to implement educational programs aiming at self-care as well as gaining knowledge about academic stress-related factors and the physical responses that may result in repercussions with serious consequences for student life such as pain, disease and dropping out of school. AD - a Public Health Department , University Center for Health Sciences, University of Guadalajara , México. AN - 29865994 AU - Pozos-Radillo, E. AU - Preciado-Serrano, L. AU - Plascencia-Campos, A. AU - Morales-Fernández, A. AU - Valdez-López, R. C2 - PMC5990944 DA - Dec DO - 10.1080/19932820.2018.1479599 DP - NLM ET - 2018/06/06 IS - 1 KW - Academic Performance/psychology Adolescent Adult Female Humans Irritable Bowel Syndrome/*epidemiology Male Mexico/epidemiology Stress, Psychological/*psychology Students, Medical/*psychology Surveys and Questionnaires Time Factors *Universities Workload/*psychology Young Adult Academic stress Guadalajara Mexico correlational study irritable bowel syndrome medical students LA - eng N1 - 1819-6357 Pozos-Radillo, Elizabeth Orcid: 0000-0002-2284-9043 Preciado-Serrano, Lourdes Orcid: 0000-0002-0329-808x Plascencia-Campos, Ana Orcid: 0000-0002-8693-3455 Morales-Fernández, Armando Orcid: 0000-0002-9249-7522 Valdez-López, Rosa Orcid: 0000-0003-1961-374x Journal Article Libyan J Med. 2018 Dec;13(1):1479599. doi: 10.1080/19932820.2018.1479599. PY - 2018 SN - 1993-2820 (Print) 1819-6357 SP - 1479599 ST - Predictive study of academic stress with the irritable bowel syndrome in medicine students at a public university in Mexico T2 - Libyan J Med TI - Predictive study of academic stress with the irritable bowel syndrome in medicine students at a public university in Mexico VL - 13 ID - 3076 ER - TY - JOUR AB - PURPOSE: The Google search engine is a resource commonly used by patients to access health-related patient education information. The American Medical Association and National Institutes of Health recommend that patient education resources be written at a level between the third and seventh grade reading levels. We assessed the readability levels of online palliative care patient education resources using 10 readability algorithms widely accepted in the medical literature. METHODS AND MATERIALS: In October 2016, searches were conducted for 10 individual terms pertaining to palliative care and oncology using the Google search engine; the first 10 articles written for the public for each term were downloaded for a total of 100 articles. The terms included palliative care, hospice, advance directive, cancer pain management, treatment of metastatic disease, treatment of brain metastasis, treatment of bone metastasis, palliative radiation therapy, palliative chemotherapy, and end-of-life care. We determined the average reading level of the articles by readability scale and Web site domain. RESULTS: Nine readability assessments with scores equivalent to academic grade level found that the 100 palliative care education articles were collectively written at a 12.1 reading level (standard deviation, 2.1; range, 7.6-17.3). Zero articles were written below a seventh grade level. Forty-nine (49%) articles were written above a high school graduate reading level. The Flesch Reading Ease scale classified the articles as "difficult" to read with a score of 45.6 of 100. The articles were collected from 62 Web site domains. Seven domains were accessed 3 or more times; among these, www.mskcc.org had the highest average reading level at a 14.5 grade level (standard deviation, 1.4; range, 13.4-16.1). CONCLUSIONS: Most palliative care education articles readily available on Google are written above national health literacy recommendations. There is need to revise these resources to allow patients and their families to derive the most benefit from these materials. AD - Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania. West Virginia University School of Medicine, Morgantown, West Virginia. Department of Radiology, Thomas Jefferson University Hospitals, Philadelphia, Pennsylvania. Departments of Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania. Department of General Internal Medicine, Section of Palliative Care and Medical Ethics, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania. Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania; Department of Otolaryngology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania. Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania. Electronic address: beriwals@upmc.edu. AN - 28341318 AU - Prabhu, A. V. AU - Crihalmeanu, T. AU - Hansberry, D. R. AU - Agarwal, N. AU - Glaser, C. AU - Clump, D. A. AU - Heron, D. E. AU - Beriwal, S. DA - Sep-Oct DO - 10.1016/j.prro.2017.01.013 DP - NLM ET - 2017/03/28 IS - 5 KW - *Comprehension Guideline Adherence Health Literacy/*methods/standards Humans Internet/*standards Medical Oncology/education/methods Palliative Care/*methods Patient Education as Topic/*methods/standards United States LA - eng N1 - 1879-8519 Prabhu, Arpan V Crihalmeanu, Tudor Hansberry, David R Agarwal, Nitin Glaser, Christine Clump, David A Heron, Dwight E Beriwal, Sushil Journal Article United States Pract Radiat Oncol. 2017 Sep-Oct;7(5):306-310. doi: 10.1016/j.prro.2017.01.013. Epub 2017 Jan 27. PY - 2017 SN - 1879-8500 SP - 306-310 ST - Online palliative care and oncology patient education resources through Google: Do they meet national health literacy recommendations? T2 - Pract Radiat Oncol TI - Online palliative care and oncology patient education resources through Google: Do they meet national health literacy recommendations? VL - 7 ID - 4123 ER - TY - JOUR AB - THE AIM OF THE WORK: Primary headache involved almost one half of the population in developmental age. This ailment still increased. Authors likes to determined endogenous and environmental factors of resulting headache in children and adolescents. MATERIAL AND METHODS: The group of 78 children and adolescents, 49 girls and 29 boys, aged 6-17 years, with primary headaches were analysed. 28 of them suffered from migraine, 43 from tension headaches and 7 from from of these types of headaches. WISC-R and WAIS-R, Bender-Koppitz and Benton tests and questionaires "who are you", ISCL-STAI and projections, discussion with children and their parents were used. Statistical analysis was done with Fisher, variations and a posteriori Scheffe tests. RESULTS: In almost all patients IQ was normal. 16-18% of children in D. Wechsler subtests showed disturbances of the memory, visual brightness, spatial, visuo-motor organisation. Subtests data were higher in children with migraine. In 22-30% of children with primary headaches intellectual development was disharmonic. In 13-21% of analysed children disturbances were present of the development visuo-motor integretion, visual memory, and specific school abilities. Emotional status in children with headaches was also disturbed. Migraineurs were rarer repressed, negative emotion and were more often self-confident. Majority of children had school problems, which was relevant to discrepancy between the level of aspirations and achievements. Moreover. children with tension headaches had more often real problems with school obligations. Almost one half of the children had family problems. CONCLUSION: Tension-type headache were more frequent in children above 12 years of age. Majority of children and adolescents with primary headache were intellectually normal, but IQ and subtest data were higher in the migrainieurs. Partial cognitive deficits could be risk factors for headache, particulary tension-type headache. Majority of children with primary headache had school problems and almost one half of them had family problems. AD - Klinika Neurologii Dzieciecej, Collegium Medicum, Uniwersytetu Jagiellońskiego, Kraków. AN - 15727022 AU - Prajsner, B. AU - Gergont, A. AU - Kaciński, M. DP - NLM ET - 2005/02/25 IS - 11 KW - Achievement Adolescent Child Cognition Disorders/diagnosis/epidemiology Female Humans Male Memory Disorders/diagnosis/epidemiology Severity of Illness Index Tension-Type Headache/diagnosis/epidemiology/*psychology Wechsler Scales LA - pol N1 - Prajsner, Barbara Gergont, Aleksandra Kaciński, Marek English Abstract Journal Article Research Support, Non-U.S. Gov't Poland Przegl Lek. 2004;61(11):1228-34. OP - Psychologiczna charakterystyka dzieci i młodziezy z samoistnymi bólami głowy. PY - 2004 SN - 0033-2240 (Print) 0033-2240 SP - 1228-34 ST - [Psychological characteristics of children and adolescents with primary headache] T2 - Przegl Lek TI - [Psychological characteristics of children and adolescents with primary headache] VL - 61 ID - 3195 ER - TY - JOUR AB - The Giessen Subjective Complaints List for Children (GSCL-C), a questionnaire on physical complaints in self-image form, was developed out of the adult GSCL. The questionnaire contains items from the areas; general wellbeing, vegetative complaints, pains, emotionality and children's complaints. The subjects is asked to estimate the degree of distress caused by each complaint (never/rarely/sometimes/often/always). Factor analysis based on a sample of 1047 schoolchildren aged 9 to 15 revealed five complaint complexes containing seven items each, which were subsequently grouped into the following scales: (1) Exhaustion, (2) Gastric Complaints, (3) Pains in Limbs, (4) Circulatory Problems, (5) Cold Symptoms. The sum of the five scales makes up the sixth scale score, overall distress. Besides describing the development of the instrument and its scales, sex- and age-related norms are given and the assessment criteria explained. Procedure and areas of application are also discussed. AN - WOS:A1992HF07500008 AU - Prehler, M. AU - Kupfer, J. AU - Brahler, E. DA - Feb IS - 2 N1 - Prehler, m kupfer, j brahler, e Kupfer, JOERG/A-5109-2008; Braehler, Elmar/C-6535-2009 Braehler, Elmar/0000-0002-2648-2728 PY - 1992 SN - 0937-2032 SP - 71-77 ST - GIESSEN SUBJECTIVE COMPLAINTS LIST FOR CHILDREN AND ADOLESCENTS T2 - Psychotherapie Psychosomatik Medizinische Psychologie TI - GIESSEN SUBJECTIVE COMPLAINTS LIST FOR CHILDREN AND ADOLESCENTS UR - ://WOS:A1992HF07500008 VL - 42 ID - 2957 ER - TY - JOUR AB - Recurrent abdominal pain in childhood can be caused structurally, functionally, metabolically or psychosomatically. In the neonatal period there occur malformations, in infancy chronic inflammations of bowel as well as obstructions due to adhesions following laparotomies or chronic intussusceptions or volvulus. In pre-school and school-age symptoms of appendicitis, lymphadenitis, Crohn's disease or Colitis ulcerosa occur. But every 8th to 9th child of school-age suffers from functional abdominal pain without structural origin, probably caused by an "irritable colon". AN - 3751069 AU - Preier, L. DA - May 31 DP - NLM ET - 1986/05/31 IS - 10 KW - *Abdomen Appendicitis/complications Child Child, Preschool Chronic Disease Diagnosis, Differential Digestive System Abnormalities Humans Meckel Diverticulum/complications Pain/*etiology Respiratory Tract Infections/complications Somatoform Disorders/etiology LA - ger N1 - Preier, L English Abstract Journal Article Austria Wien Med Wochenschr. 1986 May 31;136(10):241-3. OP - Der chronische Bauchschmerz im Kindesalter. PY - 1986 SN - 0043-5341 (Print) 0043-5341 SP - 241-3 ST - [Chronic abdominal pain in childhood] T2 - Wien Med Wochenschr TI - [Chronic abdominal pain in childhood] VL - 136 ID - 3588 ER - TY - JOUR AB - Recent literature shows that the prevalence of low back pain (LBP) in adolescents living in Western countries approaches that of adults 18-55 years of age. Moreover, epidemiological studies have also shown that the frequency of different rheumatic disorders in developing countries is similar to that found in Western industrialized regions. The purpose of this study was to ascertain the prevalence of LBP and to explore some risk factors among adolescents living in different zones of Mozambique. A previously validated questionnaire was distributed to schoolchildren of grades 6 and 7 living in three different residential/social regions of the country. Two hundred four (204) children participated in the survey. Median age was 13 years (age range 11-16 years) and 46% were boys. Several episodes of LBP interfering with usual activities during the previous year were reported by 13.5% of the sample. Living in the wealthier urban center (as compared with the peripheral regions) and walking >30 min per day to and from school were associated with an increased risk of LBP (OR 3.1, 95% CI 0.99-9.48, and OR 4.8, 95% CI 1.61-14.28, respectively). AN - WOS:000223059200007 AU - Prista, A. AU - Balague, F. AU - Nordin, M. AU - Skovron, M. L. DA - Jul DO - 10.1007/s00586-004-0683-7 IS - 4 N1 - Prista, A Balague, F Nordin, M Skovron, ML Prista, Antonio/ABE-7056-2020 Prista, Antonio/0000-0002-3652-7205 1432-0932 PY - 2004 SN - 0940-6719 SP - 341-345 ST - Low back pain in Mozambican adolescents T2 - European Spine Journal TI - Low back pain in Mozambican adolescents UR - ://WOS:000223059200007 VL - 13 ID - 2790 ER - TY - JOUR AB - PURPOSE: The primary objective of this study was to assess the prevalence of temporomandibular disorders (TMDs) and comorbid factors (sleep bruxism and headaches). This study was a cross-sectional population survey in the city of Maringá, state of Paraná, Brazil. MATERIALS AND METHODS: Axes I and II of the Research Diagnostic Criteria for TMD (RDC/TMD) were used for assessment of TMD signs and symptoms. The population was users of the Brazilian public health system (SUS), of both sexes, between the ages of 20 and 65 years, and not seeking treatment for TMD. RESULTS: The selected population (N = 1,643) was composed mostly of (a) women (65.9%), (b) married or single individuals (90.6%), (c) Caucasians (70.1%), (d) individuals aged 32.7 ± 10.3 years, (e) individuals earning a medium income (75.1%), and (f) those who had completed a high school education or higher (79.9%). According to the chronic pain grade classification (CPG) in the RDC/TMD Axis II, 36.2% of the population had some degree of TMD pain (CPG I to IV); however, only 5.1% had severe limitation due to pain (CPG III or IV). In the RDC/TMD Axis I diagnoses, 29.5% presented with muscle disorders (group I), 7.9% with disk displacements (group II), and 39.1% with other joint disorders (group III). Headaches were present in 67.9% and awake and sleep bruxism in 30% and 33.4% of the population, respectively. CONCLUSION: The prevalence of signs and symptoms of TMD was high in this population, but with low disability; however, the proportion of patients in need of treatment was much lower. AN - 26523719 AU - Progiante, P. S. AU - Pattussi, M. P. AU - Lawrence, H. P. AU - Goya, S. AU - Grossi, P. K. AU - Grossi, M. L. DA - Nov-Dec DO - 10.11607/ijp.4026 DP - NLM ET - 2015/11/03 IS - 6 KW - Adult Age Factors Aged Brazil/epidemiology Bruxism/epidemiology Cross-Sectional Studies Educational Status European Continental Ancestry Group/statistics & numerical data Female Headache/epidemiology Humans Income/statistics & numerical data Joint Dislocations/epidemiology Male Marital Status Middle Aged Population Surveillance Prevalence Sex Factors Sleep Bruxism/epidemiology Temporomandibular Joint Disc/pathology Temporomandibular Joint Disorders/diagnosis/*epidemiology Temporomandibular Joint Dysfunction Syndrome/epidemiology Young Adult LA - eng N1 - Progiante, Patrícia Saram Pattussi, Marcos Pascoal Lawrence, Herenia P Goya, Suzana Grossi, Patrícia Krieger Grossi, Márcio Lima Journal Article United States Int J Prosthodont. 2015 Nov-Dec;28(6):600-9. doi: 10.11607/ijp.4026. PY - 2015 SN - 0893-2174 (Print) 0893-2174 SP - 600-9 ST - Prevalence of Temporomandibular Disorders in an Adult Brazilian Community Population Using the Research Diagnostic Criteria (Axes I and II) for Temporomandibular Disorders (The Maringá Study) T2 - Int J Prosthodont TI - Prevalence of Temporomandibular Disorders in an Adult Brazilian Community Population Using the Research Diagnostic Criteria (Axes I and II) for Temporomandibular Disorders (The Maringá Study) VL - 28 ID - 3915 ER - TY - JOUR AB - BACKGROUND: Informed by the Pediatric Self-Management Model, the present study tested relationships between parent and family functioning, sickle cell disease (SCD) self-management, and health outcomes for children with SCD. METHOD: 83 children with SCD and a parent completed baseline data as part of a larger investigation of a family-based, problem-solving intervention for children with SCD (M age = 8.47). Youth and parents completed a measure of child health-related quality of life (HRQOL), and parents completed measures of family efficacy, parenting stress, and SCD self-management. SCD pain episodes and urgent health utilization information over the past year were obtained via medical chart review. RESULTS: SCD self-management mediated the relationship between parent-reported family efficacy and parent proxy HRQOL, as well as the relationship between parenting stress and child and parent proxy HRQOL. Mediation models were nonsignificant for outcomes beyond HRQOL, including SCD pain episodes and urgent health utilization. CONCLUSION: Fostering family efficacy and reducing parenting stress may be meaningful intervention targets for improving SCD self-management and child HRQOL among school-aged children. Although findings were consistent with the Pediatric Self-Management Model in terms of HRQOL, the model was not supported for pain episodes or urgent health utilization, highlighting the need for multi-method, longitudinal research on the SCD self-management behaviors that are linked to preventable health outcomes. AD - The Children's Hospital of Philadelphia. Rutgers University, Camden. Drexel University College of Medicine. St. Christopher's Hospital for Children. Perelman School of Medicine of the University of Pennsylvania. AN - 29048590 AU - Psihogios, A. M. AU - Daniel, L. C. AU - Tarazi, R. AU - Smith-Whitley, K. AU - Patterson, C. A. AU - Barakat, L. P. C2 - PMC6927851 DA - May 1 DO - 10.1093/jpepsy/jsx120 DP - NLM ET - 2017/10/20 IS - 4 KW - Anemia, Sickle Cell/*drug therapy Child Family/*psychology Female Humans Male Models, Psychological Parenting/psychology Parents/psychology Quality of Life/*psychology *Self-Management LA - eng N1 - 1465-735x Psihogios, Alexandra M Daniel, Lauren C Tarazi, Reem Smith-Whitley, Kim Patterson, Chavis A Barakat, Lamia P U54 HL070585/HL/NHLBI NIH HHS/United States Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't J Pediatr Psychol. 2018 May 1;43(4):423-433. doi: 10.1093/jpepsy/jsx120. PY - 2018 SN - 0146-8693 (Print) 0146-8693 SP - 423-433 ST - Family Functioning, Medical Self-Management, and Health Outcomes Among School-Aged Children With Sickle Cell Disease: A Mediation Model T2 - J Pediatr Psychol TI - Family Functioning, Medical Self-Management, and Health Outcomes Among School-Aged Children With Sickle Cell Disease: A Mediation Model VL - 43 ID - 3925 ER - TY - JOUR AB - Background: When students with intellectual disability (ID) experience pain, the pain may limit the extent to which they may engage in school activities. Although school nurses are primarily responsible for addressing students' pain, there are many barriers to identifying pain in students with ID. Aims: The purpose of the present study was to describe pain assessment practices of school nurses for students with and without ID. Design: A retrospective review was conducted of 4,660 school health office visit records for elementary school students presenting to the health office with headache, stomachache, or sore throat. Methods: Data were extracted and transcribed to a matrix. Data extracted included school grade, referral source, visit month, gender, cognitive ability, chief concern, pain assessment, external contact, and disposition. Descriptive statistics were calculated. Results: School nurses spent more time on average addressing pain in neurotypical students than in students with ID. Neurotypical students more often presented with a teacher and were dismissed from school, but parents and guardians were contacted less often for these students, when compared to students with ID. Quantified pain ratings were documented for 1% of visits. Conclusions: Because pain intensity ratings were rarely documented, the utility of such ratings in the school setting may be low. Alternatively, obtaining pain intensity ratings from younger children may be challenging without the use of appropriate tools. Nurses, teachers, and other staff providing education and care to students with ID may require pain training. Implementation of tools that elicit student pain information from parents/guardians in the school setting could decrease point-of-care contact during the school day and proactively provide information on unique child pain behaviors. (C) 2019 American Society for Pain Management Nursing. Published by Elsevier Inc. All rights reserved. AN - WOS:000536935200003 AU - Quinn, B. L. AU - Lee, S. E. AU - Bhagat, J. AU - Holman, D. W. AU - Keeler, E. A. AU - Rogal, M. DA - Jun DO - 10.1016/j.pmn.2019.08.007 IS - 3 N1 - Quinn, Brenna L. Lee, Seung Eun Bhagat, Janki Holman, David W. Keeler, Emily A. Rogal, Micaela Lee, Seung Eun/0000-0002-4173-3337 1532-8635 PY - 2020 SN - 1524-9042 SP - 233-237 ST - A Retrospective Review of School Nurse Approaches to Assessing Pain T2 - Pain Management Nursing TI - A Retrospective Review of School Nurse Approaches to Assessing Pain UR - ://WOS:000536935200003 VL - 21 ID - 1820 ER - TY - JOUR AB - Coping style plays an important role in children's wellbeing. This paper describes the patterns of associations between children's self-reported coping styles and symptoms of anxiety in order to determine whether particular dimensions are associated with better adjustment. Participants were 2566 children (1268 girls, 1298 boys) aged 7-11 years attending 15 schools in the South East of England. Results showed that aspects of coping were differentially associated with children's self-reported anxiety. Patterns of association also varied by age and gender. Dimensions of coping were shown to form distinct adaptive and maladaptive coping styles which were also differentially associated with anxiety. Analysis of these styles indicated that it is the absence of maladaptive coping strategies, rather than the presence of adaptive strategies, that is significant in emotional wellbeing. These findings suggest that interventions designed to reduce or extinguish maladaptive coping styles may be of particular benefit in facilitating emotional wellbeing. AN - WOS:000439592900002 AU - Quy, K. AU - Gibb, J. AU - Neil, L. AU - Owen, C. AU - Smith, M. DO - 10.1080/13632752.2018.1461456 IS - 3 N1 - Quy, Katie Gibb, Jennifer Neil, Louise Owen, Charlie Smith, Marjorie Owen, Charlie/C-4457-2008 Owen, Charlie/0000-0002-4560-7477 1741-2692 PY - 2018 SN - 1363-2752 SP - 230-244 ST - Dimensions of coping and anxiety symptoms in a community sample of young children T2 - Emotional and Behavioural Difficulties TI - Dimensions of coping and anxiety symptoms in a community sample of young children UR - ://WOS:000439592900002 VL - 23 ID - 2050 ER - TY - JOUR AB - Acute and chronic pain delay recovery and impair outcomes after major pediatric surgery. Understanding unique risk factors for acute and chronic pain is critical to developing effective treatments for youth at risk. We aimed to identify adolescent and family psychosocial predictors of acute and chronic postsurgical pain after major surgery in adolescents. Participants included 119 youth age 10 to 18 years (M-age = 14.9; 78.2% white) undergoing major musculoskeletal surgery and their parents. Participants completed presurgery baseline questionnaires, with youth reporting on baseline pain, anxiety, depression, insomnia and sleep quality, and parents reporting on parental catastrophizing and family functioning. At baseline, 2-week, and 4-month postsurgery, youth completed 7 days of daily pain diaries and reported on health-related quality of life. Sequential logistic regression models examined presurgery predictors of acute and chronic postsurgical pain, defined as significant pain with impairment in health-related quality of life. Acute pain was experienced by 27.2% of youth at 2 weeks, while 19.8% of youth met criteria for chronic pain at 4 months. Baseline pain predicted acute pain (odds ratio [OR] = 1.96; 95% confidence interval [CI] = 1.32-2.90), while depressive symptoms (OR = 1.22; 95%CI = 1.01-1.47), and sleep quality (OR = 0.26; 95%CI = 0.08-0.83) predicted chronic pain. Tailored interventions need to be developed and incorporated into perioperative care to address risk factors for acute and chronic pain. Perspective: Longitudinal results demonstrate adolescents' presurgery pain severity predicts acute postsurgical pain, while depressive symptoms and poor sleep quality predict chronic postsurgical pain. Tailored interventions should address separate risk factors for acute and chronic pain after adolescent surgery. (C) 2020 U.S. Association for the Study of Pain. Published by Elsevier Inc. All rights reserved. AN - WOS:000600631300012 AU - Rabbitts, J. A. AU - Palermo, T. M. AU - Zhou, C. AU - Meyyappan, A. AU - Chen, L. DA - Nov-Dec DO - 10.1016/j.jpain.2020.02.004 IS - 11-12 N1 - Rabbitts, Jennifer A. Palermo, Tonya M. Zhou, Chuan Meyyappan, Alagumeena Chen, Lucas International Symposium on Pediatric Pain Jun 18, 2019 Basel, SWITZERLAND Zhou, Chuan/0000-0002-2919-3593; Rabbitts, Jennifer/0000-0003-4800-1080 1528-8447 PY - 2020 SN - 1526-5900 SP - 1236-1246 ST - Psychosocial Predictors of Acute and Chronic Pain in Adolescents Undergoing Major Musculoskeletal Surgery T2 - Journal of Pain TI - Psychosocial Predictors of Acute and Chronic Pain in Adolescents Undergoing Major Musculoskeletal Surgery UR - ://WOS:000600631300012 VL - 21 ID - 1788 ER - TY - JOUR AB - Sickle cell disease (SCD) impacts the physical, emotional, and psychological aspects of life. We aimed to study the quality of life (QoL) in Egyptian children and adolescents with SCD using the sickle cell module in relations to social, psychological and disease variables. A cross sectional study included 40 patients with SCD between 5 and 18 years. Details of diagnosis, SCD related complications, socioeconomic status were revised. Psychological assessment was done using children depression inventory, revised Children's Manifest anxiety scale and Health related QoL for both patients and parents using a validated Arabic age specific version of sickle cell module. Significant better scores for communication problems in mothers with college degree was found compared with other academic levels with no significant difference in QoL in relation to father education and significant higher communication problems with high rate of hospitalization (P = .021). Pain score was higher in 8-13 years compared with 13-18 years age groups. Significant worse scores for worrying was found in females, P = 0.033; Depression was found in 90% of studied patients. The main determinants of QoL in patients with SCD were maternal education and frequency of hospitalization. Depression is of alarming frequency for intervention. AN - WOS:000616037800001 AU - Ragab, I. A. AU - Ellabody, M. A. M. AU - Ramy, H. A. AU - Mahmoud, N. F. AU - Sayed, S. M. DO - 10.1007/s12288-021-01396-y N1 - Ragab, Iman Ahmed Ellabody, Mohamed Abdel-Mohsen Ramy, Hisham Ahmed Mahmoud, Naglaa Fathy Sayed, Safa Matbouly 0974-0449 SN - 0971-4502 ST - Evaluation of Sickle Cell Module for Quality of Life in Egyptian Children and Adolescents Patients: Impact of Psychiatric and Disease Specific Variables T2 - Indian Journal of Hematology and Blood Transfusion TI - Evaluation of Sickle Cell Module for Quality of Life in Egyptian Children and Adolescents Patients: Impact of Psychiatric and Disease Specific Variables UR - ://WOS:000616037800001 ID - 1755 ER - TY - JOUR AB - Aims: The overall aim was to explore the relationship between recurrent pain and perceived problems with academic achievement among boys and girls in middle and late elementary school. Methods: This 3-year follow-up study was based on data from the Study of Health in School-aged Children from Umea (Sweden) and included children attending grade 6 in years 2003 and 2006, and a follow-up 3 years later in grade 9 (n = 1524, participation rate 90%). Results: Recurrent pain (head, stomach or back) at least doubled the odds of concurrent- and subsequent perceived problems with academic achievement. This applied for pain on a monthly and weekly basis, from single and multiple sites, and from each of the three studied pain sites. The odds increased with increasing pain frequency and number of pain sites. Problems with sleep, concentration or school absenteeism did not explain the association. Conclusions: Recurrent pain seems to be a potential predictor of perceived problems with academic achievement for school-aged children. This emphasises the importance of early identification and prevention of recurrent pain problems. AN - WOS:000502431400001 AU - Ragnarsson, S. AU - Johansson, K. AU - Bergstrom, E. AU - Sjoberg, G. AU - Hurtig, A. K. AU - Petersen, S. C7 - 1403494819889260 DO - 10.1177/1403494819889260 N1 - Ragnarsson, Susanne Johansson, Klara Bergstrom, Erik Sjoberg, Gunnar Hurtig, Anna-Karin Petersen, Solveig 1651-1905 SN - 1403-4948 ST - Perceived problems with academic achievement in school-aged children with recurrent pain - a longitudinal study T2 - Scandinavian Journal of Public Health TI - Perceived problems with academic achievement in school-aged children with recurrent pain - a longitudinal study UR - ://WOS:000502431400001 ID - 1863 ER - TY - JOUR AB - Aims: The overall aim was to explore the relationship between recurrent pain and perceived problems with academic achievement among boys and girls in middle and late elementary school. Methods: This 3-year follow-up study was based on data from the Study of Health in School-aged Children from Umeå (Sweden) and included children attending grade 6 in years 2003 and 2006, and a follow-up 3 years later in grade 9 (n = 1524, participation rate 90%). Results: Recurrent pain (head, stomach or back) at least doubled the odds of concurrent- and subsequent perceived problems with academic achievement. This applied for pain on a monthly and weekly basis, from single and multiple sites, and from each of the three studied pain sites. The odds increased with increasing pain frequency and number of pain sites. Problems with sleep, concentration or school absenteeism did not explain the association. Conclusions: Recurrent pain seems to be a potential predictor of perceived problems with academic achievement for school-aged children. This emphasises the importance of early identification and prevention of recurrent pain problems. AD - Department of Epidemiology and Global Health, Umeå University, Sweden. Department of Clinical Sciences, Pediatrics, Umeå University, Sweden. Department of Science and Mathematics Education, Umeå University, Sweden. AN - 31826713 AU - Ragnarsson, S. AU - Johansson, K. AU - Bergström, E. AU - Sjöberg, G. AU - Hurtig, A. K. AU - Petersen, S. DA - Dec 11 DO - 10.1177/1403494819889260 DP - NLM ET - 2019/12/13 KW - Recurrent pain backache elementary school headache perceived academic achievement school-aged children stomachache LA - eng N1 - 1651-1905 Ragnarsson, Susanne Orcid: 0000-0002-0646-7184 Johansson, Klara Bergström, Erik Sjöberg, Gunnar Hurtig, Anna-Karin Petersen, Solveig Journal Article Sweden Scand J Public Health. 2019 Dec 11:1403494819889260. doi: 10.1177/1403494819889260. PY - 2019 SN - 1403-4948 SP - 1403494819889260 ST - Perceived problems with academic achievement in school-aged children with recurrent pain - a longitudinal study T2 - Scand J Public Health TI - Perceived problems with academic achievement in school-aged children with recurrent pain - a longitudinal study ID - 3872 ER - TY - JOUR AB - Background and Purpose: Irritable bowel syndrome (IBS) is a chronic functional bowel disorder that is thought to be due to a disorder of brain-gut function and a chronic and debilitating functional gastrointestinal disorder that affects 9%-23% of the population across the world. This problem (IBS) is the second cause of absenteeism from the work and school, too. There is classification system for IBS (Rome IV classification system). Method: The purpose of this descriptive cross-sectional study was determination Prevalence of Irritable Bowel Syndrome Symptoms in High School female Students in Abadan City in 2016. In this study, using a two-part questionnaire designed by the researcher, one part of which was demographic information, and the second part was IBS symptoms, 1044 girls were classified using random sampling method. After collecting data, data were analyzed by SPSS software version 19 and descriptive statistics tests. P value less than 0.05 was considered significant. Findings: The age range of participants was between the ages of 14 and 18 and their mean age was 16 +/- 2. The findings of this study showed that the most common symptoms of IBS include abdominal pain (66.4%), diarrhea (46.7%), constipation (42.5%). Conclusion: According to the results of the study, it can be said that the symptoms of IBS are high among high school female students, thus clarifying the need for more attention to this issue. AN - WOS:000450268400027 AU - Raiesifar, Z. AU - Moradbeygi, K. AU - Tahery, N. AU - Baraz, S. AU - Shirzadegan, R. AU - Darabiyan, P. AU - Saberian, M. AU - Raiesifar, A. IS - 5 N1 - Raiesifar, Zeinab Moradbeygi, Khadijeh Tahery, Noorollah Baraz, Shahram Shirzadegan, Razieh Darabiyan, Pouriya Saberian, Mohammad Raiesifar, Afsaneh Darabiyan, Pouriya/AAL-6378-2020; Molavynejad(Baraz), shahram/G-2069-2015 Darabiyan, Pouriya/0000-0002-9529-1730; Molavynejad(Baraz), shahram/0000-0003-0113-7263 2347-2367 PY - 2018 SN - 2347-2545 SP - 170-176 ST - The Prevalence of Irritable Bowel Syndrome Symptoms in High School Students in Abadan City in 2016 T2 - Journal of Research in Medical and Dental Science TI - The Prevalence of Irritable Bowel Syndrome Symptoms in High School Students in Abadan City in 2016 UR - ://WOS:000450268400027 VL - 6 ID - 2046 ER - TY - JOUR AB - Objective To assess the health related quality of life (HRQoL) and somatization in school children with constipation. Study design This cross-sectional survey was conducted in children aged 13-18 years, in 4 schools in Gampaha district of Sri Lanka. Data were collected using a pretested, self-administered questionnaire with questions on bowel habits, somatization, and HRQoL. Constipation was diagnosed using Rome III criteria. Results A total of 1792 children were included in the analysis (males 975 [54.4%], mean age 14.4 and SD 1.3 years). One hundred thirty-eight (7.7%) fulfilled Rome criteria for constipation. Children with constipation had lower HRQoL scores for physical (83.6 vs 91.4 in controls, P < .0001), social (85.0 vs 92.7, P = .0001), emotional (73.6 vs 82.7, P =. 0001), school functioning (75.0 vs 82.5, P < .0001), and lower overall scores (79.6 vs 88.0, P = .0001). HRQoL scores were lower in those with fecal incontinence and constipation compared with constipation alone (70.0 vs 81.1, P = .004). Patient perceived severity of abdominal pain (r = -0.22, P = .01) and severity of bowel symptoms (r = -0.22, P = .01) showed significant negative correlation with total HRQoL scores. Total somatization score also found to be negatively correlated (r = -0.47, P < .0001) with HRQoL. Conclusions Children with constipation have lower HRQoL scores than controls in physical, social, emotional, and school functioning. They also have a wide range of somatic symptoms. These issues need to be addressed during clinical evaluation of children with constipation to understand the impact of the disease on the life of affected children and to provide optimal care. AN - WOS:000324873700029 AU - Rajindrajith, S. AU - Devanarayana, N. M. AU - Weerasooriya, L. AU - Hathagoda, W. AU - Benninga, M. A. DA - Oct DO - 10.1016/j.jpeds.2013.05.012 IS - 4 N1 - Rajindrajith, Shaman Devanarayana, Niranga Manjuri Weerasooriya, Lasanthi Hathagoda, Wathsala Benninga, Marc A. Devanarayana, Niranga Manjuri/0000-0002-2988-110X 1097-6833 PY - 2013 SN - 0022-3476 SP - 1069-+ ST - Quality of Life and Somatic Symptoms in Children with Constipation: A School-Based Study T2 - Journal of Pediatrics TI - Quality of Life and Somatic Symptoms in Children with Constipation: A School-Based Study UR - ://WOS:000324873700029 VL - 163 ID - 2349 ER - TY - JOUR AB - According to results from the 2007/2008 Canadian Community Health Survey, about 1 in 10 Canadians aged 12 to 44-9% of males and 12% of females, an estimated 1.5 million people--experienced chronic pain. The prevalence of chronic pain increased with age and was significantly higher among people in households where the level of educational attainment was low and among the Aboriginal population. The most common pain-related chronic conditions at ages 12 to 44 were back problems and migraine headaches. Chronic pain prevented at least a few activities in the majority of sufferers. It was associated with activity limitations and needing help with everyday tasks, and had work-related implications. Individuals with chronic pain were frequent users of health care services, and were less likely than people without chronic pain to respond positively on measures of well-being, including mood and anxiety disorders. AD - Health Analysis Division at Statistics Canada, Ottawa, Ontario K1A 0T6. Pamela.Ramage-Morin@statcan.gc.ca AN - 21269012 AU - Ramage-Morin, P. L. AU - Gilmour, H. DA - Dec DP - NLM ET - 2011/01/29 IS - 4 KW - Absenteeism Activities of Daily Living Adolescent Adult Age Factors Child Chronic Disease Female Health Services/statistics & numerical data Humans Male Mental Health/statistics & numerical data Pain/*epidemiology Pain Measurement Residence Characteristics/statistics & numerical data Sex Factors Socioeconomic Factors Young Adult LA - eng N1 - Ramage-Morin, Pamela L Gilmour, Heather Journal Article Canada Health Rep. 2010 Dec;21(4):53-61. PY - 2010 SN - 0840-6529 (Print) 0840-6529 SP - 53-61 ST - Chronic pain at ages 12 to 44 T2 - Health Rep TI - Chronic pain at ages 12 to 44 VL - 21 ID - 3143 ER - TY - CHAP A2 - Mehta, A. A2 - Beck, M. A2 - Sunder-Plassmann, G. AB - Many of the signs and symptoms of Fabry disease occur frequently in early childhood. These include acute and chronic neuropathic pain, acroparaesthesiae, hypohidrosis, angiokeratoma and gastrointestinal symptoms. Such manifestations occur in both boys and girls and may impair quality of life (QoL) and affect daily activities at home and school. Cornea verticillata is also commonly seen in affected children. In addition, although stroke, end-stage renal failure and heart failure are not found in children with Fabry disease, early signs of cerebrovascular, renal and cardiac involvement are encountered. Despite early manifestations of Fabry disease occurring in childhood, correct diagnosis is frequently delayed. Data from FOS – the Fabry Outcome Survey –and from clinical trials on the effects of enzyme replacement therapy (ERT) in children with Fabry disease have demonstrated that ERT with agalsidase alfa is well tolerated and has beneficial clinical effects on pain, QoL and gastrointestinal symptoms, at least in the short term. Early diagnosis is therefore important, because early initiation of ERT could potentially prevent or at least delay progression to end-stage organ failure. AD - Department of Academic Haematology, Royal Free and University College Medical School, London, UK Universitäts-Kinderklinik, Mainz, Germany Division of Nephrology and Dialysis, Department of Medicine III, Medical University Vienna, Vienna, Austria Department of Paediatric Endocrinology, Diabetes and Metabolism, Box 181, Addenbrooke's Hospital, Cambridge, CB2 2QQ, UK Department of Paediatrics, S. Gerardo Hospital, Monza, Italy Department of Paediatrics, University Hospital 'Germans Trias i Pujol', Badalona, Spain AN - 21290674 AU - Ramaswami, U. AU - Parini, R. AU - Pintos-Morell, G. CY - Oxford LA - eng N1 - Mehta, Atul Beck, Michael Sunder-Plassmann, Gere Ramaswami, Uma Parini, Rosella Pintos-Morell, Guillem Review Book Chapter NBK11575 [bookaccession] PB - Oxford PharmaGenesis Copyright © 2006, Oxford PharmaGenesis™. PY - 2006 ST - Natural history and effects of enzyme replacement therapy in children and adolescents with Fabry disease T2 - Fabry Disease: Perspectives from 5 Years of FOS TI - Natural history and effects of enzyme replacement therapy in children and adolescents with Fabry disease ID - 4154 ER - TY - JOUR AB - OBJECTIVE: To assess whether parental psychological and physical factors and child factors measured in the first year of life were associated with recurrent abdominal pain (RAP) in children at age 6(3/4) years. METHOD: A longitudinal cohort study (the Avon Longitudinal Study of Parents and Children), followed 8,272 children from pregnancy to age 6(3/4) years. Parental reports of child and parent functioning were gathered. Associations between parental and child functioning assessed at 6 to 8 months postpartum, and RAP measured at age 6(3/4) years were investigated. RESULTS: The prevalence of RAP in this sample was 11.8%. Both maternal anxiety (adjusted odds ratio = 1.53; 95% confidence interval 1.24-1.89) and paternal anxiety (adjusted odds ratio = 1.38; 95% confidence interval 1.12-1.71) in the first year of a child's life were associated with later childhood RAP. Parent reports of child temperament features such as irregular feeding and sleeping were also associated with later RAP. CONCLUSIONS: This is the first evidence from a prospective study that anxiety in both mothers and fathers and child temperament features predate the occurrence of RAP in children. These findings highlight the potential importance of addressing parental anxiety in families in which children present with RAP, although some caution should be exercised in their interpretation because of possible reporting bias. AU - Ramchandani, Paul G. AU - Stein, Alan AU - Hotopf, Matthew AU - Wiles, Nicola J. AU - Alspac Study, Team DA - 2006/06// DO - 10.1097/01.chi.0000215329.35928.e0 DP - PubMed IS - 6 J2 - J Am Acad Child Adolesc Psychiatry KW - Abdominal Pain Anxiety Child Cohort Studies Female Forecasting Health Status Humans Infant Male Odds Ratio Parents Recurrence Schools Students Temperament United Kingdom LA - eng PY - 2006 SN - 0890-8567 SP - 729-736 ST - Early parental and child predictors of recurrent abdominal pain at school age T2 - Journal of the American Academy of Child and Adolescent Psychiatry TI - Early parental and child predictors of recurrent abdominal pain at school age: results of a large population-based study UR - http://www.ncbi.nlm.nih.gov/pubmed/16721323 VL - 45 ID - 112 ER - TY - JOUR AB - Pediatric integrative medicine is an emerging field which, to date, has not been described in detail in academic medical centers in the United States. Early research of pediatric integrative medicine modalities shows promise for the treatment of common pediatric conditions such as irritable bowel syndrome, acute and chronic pain, headache, and allergy, among others. In light of the growing prevalence of pediatric illnesses and patient complexity, it is crucial to emphasize the patient's overall well-being. As academic centers around the world start to develop pediatric integrative medicine programs, the aim of this manuscript is to briefly highlight evidence of effective integrative treatments in pediatric subspecialties, to describe the establishment of our integrative medicine program, to summarize its early efforts, and to discuss potential barriers and keys to success. AN - WOS:000454708100013 AU - Ramesh, G. AU - Gerstbacher, D. AU - Arruda, J. AU - Golianu, B. AU - Mark, J. AU - Yeh, A. M. C7 - 168 DA - Dec DO - 10.3390/children5120168 IS - 12 N1 - Ramesh, Gautam Gerstbacher, Dana Arruda, Jenna Golianu, Brenda Mark, John Yeh, Ann Ming Ramesh, Gautam/AAJ-5222-2021 Ramesh, Gautam/0000-0003-4064-3353; Golianu, Brenda/0000-0003-0731-9535 2227-9067 PY - 2018 ST - Pediatric Integrative Medicine in Academia: Stanford Children's Experience T2 - Children-Basel TI - Pediatric Integrative Medicine in Academia: Stanford Children's Experience UR - ://WOS:000454708100013 VL - 5 ID - 1979 ER - TY - JOUR AB - OBJECTIVES: Various academic factors are known to influence pain and somatic symptoms in adolescents, but the roles of academic goal orientation, school motivational climate, and school engagement are unknown. This study examined how these understudied academic factors are associated with adolescent pain and somatic symptoms and whether sex moderates the relations. MATERIALS AND METHODS: High school students (n=90) from a high-achieving community completed questionnaires assessing academic variables, various pain characteristics, and somatic symptoms. RESULTS: The majority of adolescents (67%) experienced pain and somatic symptoms in the past month, with 56% reporting multisite pain and 58% reporting at least 1 severe somatic symptom. Headache and abdominal pain were the most frequently reported "most bothersome" pains, and pain was rated, on average, as moderately severe, typically occurring several times per month, and was primarily chronic in nature (duration, ≥3 mo). Higher levels of ego goal orientation and perceived performance motivational climate were associated with more somatic symptoms, and ego goal orientation was also associated with more intense and frequent pain. Alternatively, greater school engagement was associated with fewer somatic symptoms. Task goal orientation and mastery motivational climate were unassociated with all pain and somatic symptom outcomes. DISCUSSION: This study demonstrates that adolescents from a high-achieving community report more somatic symptoms and pain when they are less engaged in school and when their academic focus is on grades and outperforming peers. Results suggest that de-emphasizing competition and performance outcomes may support physical well-being in adolescents. AU - Randall, Edin T. AU - Shapiro, Jenna B. AU - Smith, Kelly R. AU - Jervis, Kelsey N. AU - Logan, Deirdre E. DA - 2019/12// DO - 10.1097/AJP.0000000000000765 DP - PubMed IS - 12 J2 - Clin J Pain KW - Adolescent Educational Status Ego Female Goals Humans Male Medically Unexplained Symptoms Motivation Pain Schools Sex Factors Surveys and Questionnaires LA - eng PY - 2019 SN - 1536-5409 SP - 967-974 ST - Under Pressure to Perform T2 - The Clinical Journal of Pain TI - Under Pressure to Perform: Impact of Academic Goal Orientation, School Motivational Climate, and School Engagement on Pain and Somatic Symptoms in Adolescents UR - http://www.ncbi.nlm.nih.gov/pubmed/31513055 VL - 35 ID - 62 ER - TY - JOUR AB - Oral health problems can influence people's Quality of Life (QoL) because of pain, discomfort, limitations, and other esthetics problems, affecting their social life, feeding, daily activities, and the individual's well-being. Objective: To compare oral health-related quality of life (OHRQoL) of children with and without oral clefts and their families. Materials and Methods: 121 children aged from 2 to 6 years, from both sexes, enrolled in the treatment routine of the Pediatric Dentistry Clinics of a Dental School and a Hospital for Cleft Treatment were divided into two groups: Group 1 - children with cleft lip and palate; Group 2 - children without cleft lip and palate. The OHRQoL was assessed using the validated Portuguese version of the Early Childhood Oral Health Impact Scale (B-ECOHIS). The questionnaire was answered individually, only once, at a private place. Mann-Whitney U test was used to verify differences between groups. Spearman's Rho test was used to associate sex and age with quality of life. The level of significance was set at 5% (p<0.05). Results: According to the parents' perception on the OHRQoL of children with and without cleft lip and palate, oral health of children with oral clefts (Group 1) had a statistically significant impact on OHRQoL. The correlation of sex with impact on OHRQoL did not show statistically significant differences. On the other hand, the higher the age the higher the impact on QoL. Conclusions: The group comparison revealed that the cleft lip and palate negatively impacted on OHRQoL of 2 to 6-year-old children and their parents. AN - WOS:000507906700001 AU - Rando, G. M. AU - Jorge, P. K. AU - Vitor, L. L. R. AU - Carrara, C. F. C. AU - Soares, S. AU - Silva, T. C. AU - Rios, D. AU - Machado, Maam AU - Gaviao, M. B. AU - Oliveira, T. M. C7 - e20170106 DO - 10.1590/1678-7757-2017-0106 N1 - Rando, Gabriela Mendonca Jorge, Paula Karine Ribeiro Vitor, Luciana Lourenco Carvalho Carrara, Cleide Felicio Soares, Simone Silva, Thiago Cruvinel Rios, Daniela Andrade Moreira Machado, Maria Aparecida Gaviao, Maria Beatriz Oliveira, Thais Marchini Soares, Simone/E-1810-2012; Soares, Simone/M-6744-2019; Cruvinel, Thiago/K-2707-2012; Vitor, Luciana Lourenco Ribeiro/K-2823-2012; Rios, Daniela/G-5738-2012; Carrara, Cleide F C/B-2939-2018; Oliveira, Thais Marchini/D-9576-2012; Machado, Maria Aparecida Andrade Moreira/D-8224-2012 Cruvinel, Thiago/0000-0001-7095-908X; Vitor, Luciana Lourenco Ribeiro/0000-0003-1671-0851; Rios, Daniela/0000-0002-9162-3654; Carrara, Cleide F C/0000-0002-3219-5936; Oliveira, Thais Marchini/0000-0003-3460-3144; Machado, Maria Aparecida Andrade Moreira/0000-0003-3778-7444 1678-7765 PY - 2018 SN - 1678-7757 ST - Oral health-related quality of life of children with oral clefts and their families T2 - Journal of Applied Oral Science TI - Oral health-related quality of life of children with oral clefts and their families UR - ://WOS:000507906700001 VL - 26 ID - 2058 ER - TY - JOUR AB - Background: Altered brain development is evident in children born very preterm (24-32 weeks gestational age), including reduction in gray and white matter volumes, and thinner cortex, from infancy to adolescence compared to term-born peers. However, many questions remain regarding the etiology. Infants born very preterm are exposed to repeated procedural pain-related stress during a period of very rapid brain development. In this vulnerable population, we have previously found that neonatal pain-related stress is associated with atypical brain development from birth to term-equivalent age. Our present aim was to evaluate whether neonatal pain-related stress (adjusted for clinical confounders of prematurity) is associated with altered cortical thickness in very preterm children at school age. Methods: 42 right-handed children born very preterm (24-32 weeks gestational age) followed longitudinally from birth underwent 3-D T1 MRI neuroimaging at mean age 7.9 yrs. Children with severe brain injury and major motor/sensory/cognitive impairment were excluded. Regional cortical thickness was calculated using custom developed software utilizing FreeSurfer segmentation data. The association between neonatal pain-related stress (defined as the number of skin-breaking procedures) accounting for clinical confounders (gestational age, illness severity, infection, mechanical ventilation, surgeries, and morphine exposure), was examined in relation to cortical thickness using constrained principal component analysis followed by generalized linear modeling. Results: After correcting for multiple comparisons and adjusting for neonatal clinical factors, greater neonatal pain-related stress was associated with significantly thinner cortex in 21/66 cerebral regions (p-values ranged from 0.00001 to 0.014), predominately in the frontal and parietal lobes. Conclusions: In very preterm children without major sensory, motor or cognitive impairments, neonatal pain-related stress appears to be associated with thinner cortex in multiple regions at school age, independent of other neonatal risk factors. AN - WOS:000326029300044 AU - Ranger, M. AU - Chau, C. M. Y. AU - Garg, A. AU - Woodward, T. S. AU - Beg, M. F. AU - Bjornson, B. AU - Poskitt, K. AU - Fitzpatrick, K. AU - Synnes, A. R. AU - Miller, S. P. AU - Grunau, R. E. C7 - e76702 DA - Oct DO - 10.1371/journal.pone.0076702 IS - 10 N1 - Ranger, Manon Chau, Cecil M. Y. Garg, Amanmeet Woodward, Todd S. Beg, Mirza Faisal Bjornson, Bruce Poskitt, Kenneth Fitzpatrick, Kevin Synnes, Anne R. Miller, Steven P. Grunau, Ruth E. Bjornson, Bruce Hal/A-8616-2010; Ranger, Manon/AAN-6753-2021 Bjornson, Bruce Hal/0000-0002-1465-6196; Ranger, Manon/0000-0001-8253-0686; Miller, Steven/0000-0001-9102-9105; Woodward, Todd/0000-0001-8083-0079 PY - 2013 SN - 1932-6203 ST - Neonatal Pain-Related Stress Predicts Cortical Thickness at Age 7 Years in Children Born Very Preterm T2 - Plos One TI - Neonatal Pain-Related Stress Predicts Cortical Thickness at Age 7 Years in Children Born Very Preterm UR - ://WOS:000326029300044 VL - 8 ID - 2339 ER - TY - JOUR AB - OBJECTIVE: To examine whether specific neonatal factors differentially influence cerebellar subregional volumes and to investigate relationships between subregional volumes and outcomes in very preterm children at 7 years of age. STUDY DESIGN: Fifty-six children born very preterm (24-32 weeks gestational age) followed longitudinally from birth underwent 3-dimensional T(1)-weighted neuroimaging at median age 7.6 years. Children with severe brain injury were excluded. Cerebellar subregions were automatically segmented using the multiple automatically generated templates algorithm. The relation between cerebellum subregional volumes (adjusted for total brain volume and sex) and neonatal clinical factors were examined using constrained principal component analysis. Cognitive and visual-motor integration functions in relation to cerebellar volumes were also investigated. RESULTS: Higher neonatal procedural pain and infection, as well as other clinical factors, were differentially associated with reduced cerebellar volumes in specific subregions. After adjusting for clinical risk factors, neonatal procedural pain was distinctively associated with smaller volumes bilaterally in the posterior VIIIA and VIIIB lobules. Specific smaller cerebellar subregional volumes were related to poorer cognition and motor/visual integration. CONCLUSIONS: In very preterm children, exposure to painful procedures, as well as additional neonatal risk factors such as infection, were associated with reduced cerebellar volumes in specific subregions and poorer outcomes at school age. AU - Ranger, Manon AU - Zwicker, Jill G. AU - Chau, Cecil M. Y. AU - Park, Min Tae M. AU - Chakravarthy, M. Mallar AU - Poskitt, Kenneth AU - Miller, Steven P. AU - Bjornson, Bruce H. AU - Tam, Emily W. Y. AU - Chau, Vann AU - Synnes, Anne R. AU - Grunau, Ruth E. DA - 2015/08// DO - 10.1016/j.jpeds.2015.04.055 DP - PubMed IS - 2 J2 - J Pediatr KW - Cerebellum Child Child Development Cognition Female Humans Infant, Extremely Premature Infant, Newborn Infant, Premature Infections Intensive Care Units, Neonatal Longitudinal Studies Magnetic Resonance Imaging Male Pain Risk Factors LA - eng PY - 2015 SN - 1097-6833 SP - 292-298.e1 ST - Neonatal Pain and Infection Relate to Smaller Cerebellum in Very Preterm Children at School Age T2 - The Journal of Pediatrics TI - Neonatal Pain and Infection Relate to Smaller Cerebellum in Very Preterm Children at School Age UR - http://www.ncbi.nlm.nih.gov/pubmed/25987534 VL - 167 ID - 81 ER - TY - JOUR AB - Children with acute pancreatitis may develop chronic abdominal wall pain after resolution of clinical, laboratory, and radiographic signs of disease. We describe a 13-year-old boy who underwent an unrevealing, complex diagnostic evaluation for persistent abdominal pain after resolution of acute pancreatitis. His pain required an extended leave of absence from school and nasogastric tube feeds. After receiving abdominal nerve blocks and trigger point injections, he experienced near-complete resolution of pain with normalization of eating habits and daily function. Pain practitioners should think critically about the signs and symptoms of visceral versus somatic pain and try newer diagnostic interventions that may be therapeutic. AN - WOS:000474142500011 AU - Rappold, T. AU - Suleman, M. I. DA - Jul DO - 10.1213/xaa.0000000000000980 IS - 1 N1 - Rappold, Tommy, Jr. Suleman, M-Irfan PY - 2019 SN - 2325-7237 SP - 34-36 ST - Functional Abdominal Pain in a Pediatric Patient After Resolution of Acute Pancreatitis: A Case Report T2 - A & a Practice TI - Functional Abdominal Pain in a Pediatric Patient After Resolution of Acute Pancreatitis: A Case Report UR - ://WOS:000474142500011 VL - 13 ID - 1904 ER - TY - JOUR AB - Medically unexplained or functional somatic symptoms (FSS) in children constitute a major clinical problem. However, research data on FSS in young children are few, and epidemiological studies are hampered by lack of good standardised measures. The present thesis consists of two studies: In study one, we developed two measures to assess FSS in young children. The first measure is a parent interview, the Soma Assessment Interview (SAI), to assess the 1-year prevalence and associated impairment caused by FSS. The interview can be performed by lay interviewers and subsequently rated clinically by physicians. A preliminary validation showed a good agreement on FSS recognition between two clinical raters (kappa = 0.86), a good concurrent validity with independent measures of physical complaints and a good discrimination on the prevalence of FSS between a community sample and clinical samples. The second measure is a systematic medical record review of FSS in paediatric patients: the Medical Record Review for Functional Somatic Symptoms in Children (MRFC). Our findings suggest that the MRFC allows identification of subgroups of paediatric patients with multisymptomatic FSS and long-term and/or impairing FSS and it may prove useful for case finding in clinical and epidemiological research. In study two, we investigated the parent-reported FSS and their impairment in a population-based sample of Danish 5-7-year-old children. We used the SAI as the main measure. Data from 1,327 children from The Copenhagen Child Cohort 2000 were analysed. Impairing symptoms were defined as FSS causing substantial discomfort, impairment of everyday life, absence from daycare or school and/or health care seeking. We found that FSS are common in this age group with a 1-year prevalence of 23.2%. Different pain complaints, i.e. limb pain, abdominal pain and headache, were the most prevalent types of FSS. A subgroup of children with impairing FSS (4.4%) was identified. These children were more likely to present multisymptomatic FSS than children with non-impairing FSS. Health anxiety symptoms (HAS) and their associations with different physical health variables, including FSS, were investigated in the same population of 5-7-year-old children. In total, 2.4% presented prominent HAS, and the level of HAS was correlated with general poor health, chronic physical disease and physical complaints including FSS. In children with FSS, we found significant associations between the level of HAS and the impact of the childrens´ FSS in terms of number of doctor's visits and missed school and/or daycare due to FSS as well as the degree of parental worries about the childrens´ FSS. Furthermore, HAS were significantly associated with emotional symptoms. The findings suggest an early onset of somatisation and point to the need for clinical and preventive intervention in a substantial proportion of children. The findings also suggest a close link between HAS, FSS and emotional symptoms. Medically unexplained or functional somatic symptoms (FSS) in children constitute a major clinical problem. However, research data on FSS in young children are few, and epidemiological studies are hampered by lack of good standardised measures. AD - The Research Clinic for Functional Disorders and Psychosomatics, Aarhus University Hospital, C, Denmark. charrask@rm.dk AN - 23171751 AU - Rask, C. U. DA - Nov DP - NLM ET - 2012/11/23 IS - 11 KW - *Affective Symptoms Age of Onset Child Child Behavior Child, Preschool *Chronic Disease/epidemiology/psychology Denmark/epidemiology Early Medical Intervention Female Health Status Disparities Humans Interviews as Topic Male Medical Records *Pain/diagnosis/etiology Pain Measurement Parents/psychology Prevalence Reproducibility of Results *Somatoform Disorders/classification/diagnosis/epidemiology/physiopathology/psychology Surveys and Questionnaires LA - eng N1 - 2245-1919 Rask, Charlotte Ulrikka Journal Article Review Denmark Dan Med J. 2012 Nov;59(11):B4537. PY - 2012 SN - 2245-1919 SP - B4537 ST - Functional somatic symptoms in 5-7 year old children: assessment, prevalence and co-occurrence T2 - Dan Med J TI - Functional somatic symptoms in 5-7 year old children: assessment, prevalence and co-occurrence VL - 59 ID - 3305 ER - TY - JOUR AB - Research on somatisation or functional disorders, characterised by the subjective report of physical symptoms in the absence of clear physical pathology, in young children is limited. This study investigates the distribution, types and co-occurrence of parent-reported functional somatic symptoms (FSS) and their impairment in a population-based sample of Danish 5-7-year-old children. Data were obtained from a 5-7-year follow-up of the Copenhagen Child Cohort 2000. The entire study population included 3,000 randomly sampled children from the cohort. Among these FSS measures were obtained for 1,327 children. The newly introduced parent interview, the soma assessment interview, was used to assess the child's FSS. Impairing symptoms were defined as FSS that caused substantial discomfort, impairment of everyday life, absence from day-care or school and/or help-seeking in the health care system. The 1-year prevalence of any FSS was 23.2% (N = 308) and higher in girls than boys (27.6 vs. 18.8%, P < 0.0001). Impairing FSS were found in 4.4% (N = 58). Pain complaints, i.e. limb pain, headache and abdominal pain, were the most frequently reported FSS. Among the 308 children with FSS, 66 (21.4%) presented with two or more of these functional pain complaints, while 15 (4.9%) had all three types. The findings indicate that FSS are common health complaints in 5-7-year-old children. A subgroup with impairing FSS with a likely need of clinical intervention was identified. This suggests that a somatisation pattern may start early in life and call for future studies to include associated impairment in the investigation of childhood FSS. AN - WOS:000270869900006 AU - Rask, C. U. AU - Olsen, E. M. AU - Elberling, H. AU - Christensen, M. F. AU - Ornbol, E. AU - Fink, P. AU - Thomsen, P. H. AU - Skovgaard, A. M. DA - Oct DO - 10.1007/s10654-009-9366-3 IS - 10 N1 - Rask, Charlotte Ulrikka Olsen, Else Marie Elberling, Hanne Christensen, Mogens Fjord Ornbol, Eva Fink, Per Thomsen, Per Hove Skovgaard, Anne Mette Fink, Per/AAA-2297-2021 Rask, Charlotte Ulrikka/0000-0002-7426-0353; Fink, Per/0000-0003-2921-4099; Skovgaard, Anne Mette/0000-0002-8793-8303; Olsen, Else Marie/0000-0002-7240-9767 1573-7284 PY - 2009 SN - 0393-2990 SP - 625-634 ST - Functional somatic symptoms and associated impairment in 5-7-year-old children: the Copenhagen Child Cohort 2000 T2 - European Journal of Epidemiology TI - Functional somatic symptoms and associated impairment in 5-7-year-old children: the Copenhagen Child Cohort 2000 UR - ://WOS:000270869900006 VL - 24 ID - 2586 ER - TY - JOUR AB - Objective To investigate infancy predictors of impairing functional somatic symptoms (FSS) at child ages 5-7 years with a focus on problems with feeding, sleep, and tactile reactivity. Study design This study is part of a longitudinal birth cohort study, Copenhagen Child Cohort CCC2000. Child health, development, and functioning were assessed by community health nurses at 4 home visits from birth to age 10 months. FSS at ages 5-7 years were measured by the Soma Assessment Interview in 1327 children. Sociodemographic data and information on maternal psychiatric illness were obtained from the Danish National Registers. Results Multiple logistic regression analysis controlled for maternal psychiatric illness and annual household income revealed that combined infancy regulatory problems (ie, at least 2 of 3 problems of feeding, sleeping, or tactile reactivity during the first 10 months of living) predicted impairing FSS at 5-7 years (aOR = 2.9, 95% CI: 1.3-6.6). Maternal psychiatric illness during the child's first year of living was also associated with later child FSS (aOR = 7.1, 95% CI: 1.8-27.8). Conclusion Regulatory problems may be an early marker of disturbed sensory reactivity in young children, which together with maternal psychiatric problems, point to possible early risk mechanisms of impairing FSS in childhood. (J Pediatr 2013;162:335-42). AN - WOS:000313579900025 AU - Rask, C. U. AU - Ornbol, E. AU - Olsen, E. M. AU - Fink, P. AU - Skovgaard, A. M. DA - Feb DO - 10.1016/j.jpeds.2012.08.001 IS - 2 N1 - Rask, Charlotte Ulrikka Ornbol, Eva Olsen, Else Marie Fink, Per Skovgaard, Anne Mette Fink, Per/AAA-2297-2021 Fink, Per/0000-0003-2921-4099; Rask, Charlotte Ulrikka/0000-0002-7426-0353; Skovgaard, Anne Mette/0000-0002-8793-8303; Olsen, Else Marie/0000-0002-7240-9767 PY - 2013 SN - 0022-3476 SP - 335-342 ST - Infant Behaviors Are Predictive of Functional Somatic Symptoms at Ages 5-7 Years: Results from the Copenhagen Child Cohort CCC2000 T2 - Journal of Pediatrics TI - Infant Behaviors Are Predictive of Functional Somatic Symptoms at Ages 5-7 Years: Results from the Copenhagen Child Cohort CCC2000 UR - ://WOS:000313579900025 VL - 162 ID - 2385 ER - TY - JOUR AB - BACKGROUND: Patellofemoral pain (PFP) is common among adolescents and associated with long-lasting pain and disability. Patient education and exercise therapy are commonly used treatments in primary and secondary care but the effect of these treatments in adolescents is unknown. We aimed to determine the effect of exercise therapy as an add-on therapy to patient education compared with education alone. METHODS: 121 adolescents from 15-19 years of age were cluster randomised to patient education or patient education combined with exercise therapy. Patient education covered self-management of pain and information on PFP. Exercise therapy consisted of supervised exercises on school premises (3/week for 3 months) and instructions on home-based exercises. Adherence to exercises was assessed as attendance and weekly text messages. Primary outcome measure was self-reported recovery (seven-point Likert scale) at 12 months with additional follow-ups at 3, 6 and 24 months. RESULTS: Adolescents randomised to patient education and exercise therapy were more likely to have recovered at 12 months (OR, 1.73, 95% CI 1.02 to 2.93, number needed to treat (NNT) of 11). Similar results were observed at 3 and 6 months (OR 1.88 and 1.43) while the effect was further increased at 24 months (OR of 2.52, NNT of 5). A higher total number of weekly exercise sessions increased the odds of recovery. CONCLUSIONS: In adolescent PFP, the addition of exercise therapy for 3 months was more effective than patient education alone. The effect was apparent at 3 months and increased up to 2 years. Adherence to exercises was important and improved the odds of recovery. TRIAL REGISTRATION NUMBER: clinicaltrials.gov reference: NCT01438762. AU - Rathleff, M. S. AU - Roos, E. M. AU - Olesen, J. L. AU - Rasmussen, S. DA - 2015/03// DO - 10.1136/bjsports-2014-093929 DP - PubMed IS - 6 J2 - Br J Sports Med KW - Adolescent Cluster Analysis Combined Modality Therapy Exercise rehabilitation Exercise Therapy Female Humans Knee Male Patellofemoral Pain Syndrome Patient Compliance Patient Education as Topic School Health Services Treatment Outcome LA - eng PY - 2015 SN - 1473-0480 SP - 406-412 ST - Exercise during school hours when added to patient education improves outcome for 2 years in adolescent patellofemoral pain T2 - British Journal of Sports Medicine TI - Exercise during school hours when added to patient education improves outcome for 2 years in adolescent patellofemoral pain: a cluster randomised trial UR - http://www.ncbi.nlm.nih.gov/pubmed/25388552 VL - 49 ID - 94 ER - TY - JOUR AB - BACKGROUND: Knee pain is common during adolescence. Adolescents and their parents may think that knee pain is benign and self-limiting and therefore avoid seeking medical care. However, long-term prognosis of knee pain is not favourable and treatment seems to offer greater reductions in pain compared to a "wait-and-see" approach. The purpose of this study was to describe the determinants of care-seeking behaviour among adolescents with current knee pain and investigate what types of treatment are initiated. METHODS: An online questionnaire was forwarded to 2,846 adolescents aged 15-19 in four upper secondary schools. The questionnaire contained questions on age, gender, height, weight, currently painful body regions, frequency of knee pain, health-related quality of life measured by the EuroQol 5-dimensions, sports participation and if they had sought medical care. Adolescents who reported current knee pain at least monthly or more frequently were telephoned. The adolescents were asked about pain duration, onset of knee pain (traumatic or insidious) and if they were currently being treated for their knee pain. RESULTS: 504 adolescents currently reported at least monthly knee pain. 59% of these had sought medical care and 18% were currently under medical treatment . A longer pain duration and higher pain severity increased the odds of seeking medical care. Females with traumatic onset of knee pain were more likely to have sought medical care than females with insidious onset of knee pain. Females with traumatic onset of knee pain and increased pain severity were more likely to be undergoing medical treatment. The most frequently reported treatments were the combination of exercises and orthotics (68% of those undergoing medical treatment). CONCLUSION: Females with insidious onset of knee pain do not seek medical care as often as those with traumatic onset and adolescents of both genders with insidious onset are less likely to be under medical treatment. These findings are important as knee pain with insidious onset has similar consequences as knee pain with traumatic onset regarding pain severity, pain duration and reductions in health-related quality of life. AD - Health, Aarhus University, Aarhus, Denmark. misr@rn.dk AN - 23899043 AU - Rathleff, M. S. AU - Skuldbøl, S. K. AU - Rasch, M. N. AU - Roos, E. M. AU - Rasmussen, S. AU - Olesen, J. L. C2 - PMC3729825 DA - Jul 30 DO - 10.1186/1471-2474-14-225 DP - NLM ET - 2013/08/01 KW - Adolescent Female *Health Behavior Health Services Accessibility Humans Knee Joint/*pathology/physiopathology Male Pain/diagnosis/*psychology Pain Management/*methods Patient Acceptance of Health Care/*psychology/statistics & numerical data Population Surveillance Quality of Life Surveys and Questionnaires Young Adult LA - eng N1 - 1471-2474 Rathleff, Michael S Skuldbøl, Sune K Rasch, Mads N B Roos, Ewa M Rasmussen, Sten Olesen, Jens L Journal Article BMC Musculoskelet Disord. 2013 Jul 30;14:225. doi: 10.1186/1471-2474-14-225. PY - 2013 SN - 1471-2474 SP - 225 ST - Care-seeking behaviour of adolescents with knee pain: a population-based study among 504 adolescents T2 - BMC Musculoskelet Disord TI - Care-seeking behaviour of adolescents with knee pain: a population-based study among 504 adolescents VL - 14 ID - 3755 ER - TY - JOUR AB - BACKGROUND Dermatomycosis is a superficial skin disease caused by the species of the genera Trichophyton, Microsporum and Epidermophyton which are highly specialised parasites interrelated by their common morphological features and physiological adaptations to a parasitic mode of existence on keratinised tissue of man and animal. Tinea capitis, ringworm of the scalp and is of worldwide distribution. While most species of Trichophyton and Microsporum can cause Tinea capitis, it is interesting that Epidermophyton floccosum, Trichophyton concentricum and Trichophyton interdigitale never cause Tinea capitis. It was found that the incidence of Tinea capitis was more in South India than North India and was more common in males than females and the commonest age group was 1-10 years. MATERIALS AND METHODS Suspected cases of Tinea capitis, attending the Department of DVL, Osmania General Hospital, Hyderabad for a period of eight months, from October 2015 to May 2016 were included in the present study. A detailed history was taken and complete clinical examination was done in all the patients and the details were recorded in the proforma enclosed. Later all the cases were subjected to direct microscopic examination (10% KOH) and culture on Sabouraud dextrose agar medium, and the results were recorded in the proforma. RESULTS Of the 708 patients with dermatophytosis, who attended the DVL Department of Osmania General Hospital, Hyderabad during the period of study, 100 cases were of Tinea capitis which gives a prevalence of 14.12%. 93 out of 100 patients belonged to 1-12 years age group i.e. prepubertal children and only one patient was beyond 18 years. Coming to the incidence of sex in present series, out of 100 patients 49 (49%) were males and 51% females with a male to female ratio of 1:1.1. Majority of patients in present series were school children i.e. 86 out of 100, 13 were preschool children and one adult female was housewife. Out of 100 cases, only 24 patients gave history of contact with dogs either in the house or outside. 32 out of 100 patients gave history of contact with Tinea infection among family members. 72 out of 100 had the disease for 2 weeks to 2 months. Only 6 (6%) patients had associated Tinea corporis lesion over the body. All the 100 patients had the symptom of hair loss, though the severity varied from case to case. Only 31 (31%) patients complained of itching and all the 15 patients with kerion experienced pain. All the four types of clinical manifestation described in Tinea capitis were seen in the present study. Grey scaly type predominated 51 (51%) with cases followed by Black dot type with 30 (30%) cases, Kerion 15 (15%) and agminate folliculitis (4%) cases. CONCLUSION Trichophyton violaceum was found to be the commonest species (44.90%) followed by T. rubrum (28.57%), T. mentagrophytes 12.24%; species of the Microsporum 2.05%, and Epidermophyton were not encountered in present study. 90.7% of them belonged to socially and economically backward sections who live in overcrowded and congested areas. Common usage of combs and towels was present among family members in all cases. It is suggested that more number of studies of similar nature may throw some more light in this direction. AN - WOS:000394677600008 AU - Reddy, D. S. AU - Prasad, Jvds AU - Prasad, K. N. AU - Yashwanth, T. DA - Oct DO - 10.14260/jemds/2016/1415 IS - 84 N1 - Reddy, D. Subash Prasad, J. V. D. S. Prasad, K. Narasimha Yashwanth, T. 2278-4802 PY - 2016 SN - 2278-4748 SP - 6257-6263 ST - CLINICOMYCOLOGICAL STUDY OF TINEA CAPITIS T2 - Journal of Evolution of Medical and Dental Sciences-Jemds TI - CLINICOMYCOLOGICAL STUDY OF TINEA CAPITIS UR - ://WOS:000394677600008 VL - 5 ID - 2140 ER - TY - JOUR AB - OBJECTIVE: To examine effects of preseason baseline headache and posttraumatic headache (PTH) on neurocognitive function. DESIGN: Retrospective repeated measures study with headache groups formed regarding baseline headache score (0 = negative headache; 1-6 = positive headache) and day 1 postinjury headache score (0 = no headache; 1-2 = mild headache; 3-6 = moderate-severe headache). SETTING: Clinical athletic training setting and sports medicine research laboratory. PARTICIPANTS: High-school and collegiate athletes with a concussion. INDEPENDENT VARIABLES: Preseason baseline headache, PTH, test-day. MAIN OUTCOME MEASURES: A Graded Symptom Checklist (GSC) was used to assess symptoms. The Automated Neuropsychological Assessment Metrics (ANAM) and the Standardized Assessment of Concussion (SAC) were used to assess neuropsychological function and mental status. The Balance Error Scoring System (BESS) was used to assess postural stability. RESULTS: Both baseline headache groups displayed a higher symptom endorsement and higher symptom severity at day 1 postinjury and improved by day 7 postinjury. The positive headache group reported an even greater increase in symptom severity and presence (P < 0.05). ANAM revealed deficits in both groups 1 day postinjury. All PTH headache groups displayed a difference in symptom number and severity with the increase being magnified by headache severity (P < 0.05). Individuals reporting moderate-severe PTH displayed increased deficits subacutely but improved by 5-7 days postinjury on overall neuropsychological performance, reaction time, and working memory (P < 0.05). Deficits were observed for all ANAM measures except simple reaction time 1 (SRT 1) and match to sample subacutely and improved over time (P < 0.05). The SAC yielded an interaction (P < 0.05) for baseline headache. The BESS yielded no significant findings. CONCLUSIONS: Clinicians should consider headache when assessing concussion and during preseason baseline assessments because headache may affect symptom presence and other clinical measures of concussion. AD - Department of Exercise and Sports Science, Sports Medicine Research Laboratory, University of North Carolina, Chapel Hill, North Carolina 27599, USA. johnakay@email.unc.edu AN - 17620782 AU - Register-Mihalik, J. AU - Guskiewicz, K. M. AU - Mann, J. D. AU - Shields, E. W. DA - Jul DO - 10.1097/JSM.0b013e31804ca68a DP - NLM ET - 2007/07/11 IS - 4 KW - Adolescent *Athletic Injuries Brain Concussion/complications/physiopathology Cognition Disorders/etiology/*physiopathology Female Humans Male Post-Traumatic Headache/*psychology Retrospective Studies Sports Sports Medicine Surveys and Questionnaires United States LA - eng N1 - Register-Mihalik, Johna Guskiewicz, Kevin M Mann, John Douglas Shields, Edgar W Journal Article United States Clin J Sport Med. 2007 Jul;17(4):282-8. doi: 10.1097/JSM.0b013e31804ca68a. PY - 2007 SN - 1050-642X (Print) 1050-642x SP - 282-8 ST - The effects of headache on clinical measures of neurocognitive function T2 - Clin J Sport Med TI - The effects of headache on clinical measures of neurocognitive function VL - 17 ID - 3777 ER - TY - JOUR AB - Chronic pain is a significant problem in children and teens, and adolescents with chronic pain often struggle to attend school on a regular basis. We present in this article a novel program we developed that integrates attendance at a group cognitive-behavioural chronic pain self-management program with earning high school credits. We collaborated with Alberta Education in the development of this course, Chronic Pain 35. Adolescents who choose to enroll are invited to demonstrate their scientific knowledge related to pain, understanding of and engagement with treatment homework, and demonstrate their creativity by completing a project, which demonstrates at least one concept. Integrating Chronic Pain 35 into an adolescent's academic achievements is a creative strategy that facilitates the engagement of adolescents in learning and adopting pain coping techniques. It also helps teens to advocate for themselves in the school environment and improve their parents' and teachers' understanding of adolescent chronic pain. This is one of the first successful collaborations between a pediatric health program and provincial education leaders, aimed at integrating learning and obtaining school credit for learning about and engaging in health self-management for teens. The authors hope this paper serves as an effective reference model for any future collaborating programs aimed at supporting teens with chronic pain to obtain high school credits. AU - Reid, Kathy AU - Simmonds, Mark AU - Verrier, Michelle AU - Dick, Bruce DA - 2016/11/19/ DO - 10.3390/children3040031 DP - PubMed IS - 4 J2 - Children (Basel) KW - adolescent chronic pain cognitive-behavioural therapy school LA - eng PY - 2016 SN - 2227-9067 ST - Supporting Teens with Chronic Pain to Obtain High School Credits T2 - Children (Basel, Switzerland) TI - Supporting Teens with Chronic Pain to Obtain High School Credits: Chronic Pain 35 in Alberta UR - http://www.ncbi.nlm.nih.gov/pubmed/27869766 VL - 3 ID - 66 ER - TY - JOUR AB - Objectives:Children and adolescents diagnosed as having Crohn disease (CD), a type of inflammatory bowel disease (IBD), have increased vulnerability for anxiety symptoms that may be related to disease-related processes. The aims of this article are 3-fold: to report the proportion of pediatric patients with CD whose self-reported anxiety symptoms are indicative of distress, to describe the constellation of anxiety symptoms, and to examine the relation between anxiety and disease symptoms.Methods:Retrospective medical chart review was performed for 93 youths with CD (ages 9-18 years) who had completed the Screen for Child Anxiety Related Disorders during their gastroenterology visit. Medical records were reviewed for demographic and disease characteristics. the Harvey-Bradshaw Index (HBI) was used as a measure of CD activity.Results:Thirty percent of the youths reported experiencing elevated anxiety symptoms (Screen for Child Anxiety Related Disorder score >20), and 50% had scored above the cutoff in 1 or more anxiety domains, with school anxiety, general anxiety, and separation anxiety symptoms reported most frequently. Youth rated with moderate/severe disease activity on the HBI (n=4) self-reported more anxiety symptoms compared with youth with inactive disease (n=78, P=0.03). Greater school anxiety was significantly associated with decreased well-being (P=0.003), more abdominal pain (P<0.001), and the number of loose stools (P=0.01). Having extraintestinal symptoms was significantly associated with higher somatic/panic anxiety (P=0.01).Conclusions:Implementing a brief anxiety screen in tertiary pediatric settings may be one approach to identify young patients with CD in distress. Health care providers should consider periodic assessment of school anxiety among youth with CD. AN - WOS:000348460100013 AU - Reigada, L. C. AU - Hoogendoorn, C. J. AU - Walsh, L. C. AU - Lai, J. AU - Szigethy, E. AU - Cohen, B. H. AU - Bao, R. J. AU - Isola, K. AU - Benkov, K. J. DA - Jan DO - 10.1097/mpg.0000000000000552 IS - 1 N1 - Reigada, Laura C. Hoogendoorn, Claire J. Walsh, Lindsay C. Lai, Joanne Szigethy, Eva Cohen, Barry H. Bao, Ruijun Isola, Kimberly Benkov, Keith J. Cohen, Barry H./AAT-7408-2020; Hoogendoorn, Claire J./M-4514-2019; Cohen, Barry/ABG-9235-2020 Cohen, Barry/0000-0002-6241-1927; Hoogendoorn, Claire/0000-0003-4526-1952; Bao, Ruijun/0000-0003-2578-6321 1536-4801 PY - 2015 SN - 0277-2116 SP - 30-35 ST - Anxiety Symptoms and Disease Severity in Children and Adolescents With Crohn Disease T2 - Journal of Pediatric Gastroenterology and Nutrition TI - Anxiety Symptoms and Disease Severity in Children and Adolescents With Crohn Disease UR - ://WOS:000348460100013 VL - 60 ID - 2261 ER - TY - JOUR AB - BACKGROUND: Crohn's disease (CD) is a chronic inflammatory bowel disease usually diagnosed in early adult life and characterized by unpredictable flares and debilitating symptoms such as diarrhea, abdominal pain, and fever, which can interfere with a patient's ability to work and perform daily activities. OBJECTIVE: The aim of this study was to assess the validity, reliability, and responsiveness of the Work Productivity and Activity Impairment questionnaire in CD (WPAI:CD). METHODS: The WPAI:CD was tested in CD patients enrolled in a 26-week randomized clinical trial of cer-tolizumab pegol versus placebo. Discriminative validity of WPAI:CD absenteeism, presenteeism(reduced on-the-job effectiveness), overall work productivity loss (absenteeism + presenteeism), and activity impairment scores was assessed relative to 5 measures of disease severity and health status: CD Activity Index (CDAI), Short Form-36 physical component summary (PCS) and mental health component summary (MCS) scores, Inflammatory Bowel Disease Questionnaire (IBDQ), and the 5-dimensional EuroQoL health-related quality-of-life visual analog scale (EQ-VAS). Responsiveness was assessed by comparing changes in WPAI:CD scores from baseline to week 26 for patients in remission (CDAI <150 points) versus no remission. Standardized Response Means (SRMs) were calculated to evaluate the magnitude of the changes. RESULTS: A total of 662 patients (mean [range] age, 37.4 [18-77] years; male, 288 [43.5%]; white, 629 [95.0%]) were enrolled in the study. Patients with CD of the worst severity (CDAI > median) showed significantly higher impairment in work (+10.5%) and activities (+10.4%) versus patients with "best health" (no problems) (both, P < or = 0.001). Patients with "worst" IBDQ, PCS, MCS, and EQ-VAS scores also showed significantly higher impairments in work (IBDQ, VAS -24.2%; PCS, -24.1%; MCS, -15.9%; EQ-VAS, -16.5%) and activities (IBDQ, -23.3%; PCS, -21.8%; MCS, -16.5%; EQ-VAS, -17.2%) versus "best" scores (all, P < 0.05). There were significant differences between WPAI:CD impairment scores for patients in remission versus patients failing to achieve remission (P < 0.05). SRMs were small (ie, <0.5) in the nonre-mission group, and moderate to large (ie, >0.5) for patients in remission. CONCLUSIONS: The discriminative validity, reliability, and responsiveness of the WPAI:CD were demonstrated. The WPAI:CD may be useful for evaluating drug impact on CD. AD - Margaret Reilly Associates, New York, New York, USA. AN - 18343277 AU - Reilly, M. C. AU - Gerlier, L. AU - Brabant, Y. AU - Brown, M. DA - Feb DO - 10.1016/j.clinthera.2008.02.016 DP - NLM ET - 2008/03/18 IS - 2 KW - *Absenteeism *Activities of Daily Living Adolescent Adult Aged Antibodies, Monoclonal, Humanized Certolizumab Pegol *Cost of Illness Crohn Disease/*diagnosis/drug therapy/physiopathology/psychology Female Gastrointestinal Agents/therapeutic use Humans Immunoglobulin Fab Fragments/therapeutic use Male Middle Aged Polyethylene Glycols/therapeutic use Predictive Value of Tests Quality of Life Reproducibility of Results Severity of Illness Index *Sick Leave *Surveys and Questionnaires Time Factors Treatment Outcome Young Adult LA - eng N1 - 1879-114x Reilly, Margaret C Gerlier, Laetitia Brabant, Yves Brown, Martin Journal Article Multicenter Study Randomized Controlled Trial Research Support, Non-U.S. Gov't Validation Study United States Clin Ther. 2008 Feb;30(2):393-404. doi: 10.1016/j.clinthera.2008.02.016. PY - 2008 SN - 0149-2918 SP - 393-404 ST - Validity, reliability, and responsiveness of the work productivity and activity impairment questionnaire in Crohn's disease T2 - Clin Ther TI - Validity, reliability, and responsiveness of the work productivity and activity impairment questionnaire in Crohn's disease VL - 30 ID - 3847 ER - TY - JOUR AB - The spectrum of diseases in childhood has changed in the last two decades. The prevalence of disease patterns characterized by behavior disorders and/or distinctive psychosocial aspects has significantly increased. These disorders include regulatory disturbances in infancy, such as excessive crying and early-childhood eating problems, attention-deficit hyperactivity disorder in school-age children; eating disorders such as obesity and anorexia; and an increased rate of depression and delinquency in adolescence. Furthermore, chronic diseases have increased, Including bronchial asthma, diabetes mellitus, and chronic infectious intestinal diseases, which can have a negative impact on the psychosocial development of the child and the whole family system Regarding the roles of pediatrician on the one hand and child psychiatrist on the other hand, the former has a special key role as "gatekeeper, "Pediatrics, social pediatrics, and child psychiatry should work more closely together to guarantee optimal care for these children. At the same time, research on the etiopathogenesis of the above-mentioned diseases is needed AN - WOS:000274143900005 AU - Reinhardt, D. AU - Petermann, F. DA - Jan DO - 10.1007/s00112-009-2056-0 IS - 1 N1 - Reinhardt, D. Petermann, F. PY - 2010 SN - 0026-9298 SP - 15-+ ST - Pediatrics and child and adolescent psychiatry. Where do they overlap? T2 - Monatsschrift Kinderheilkunde TI - Pediatrics and child and adolescent psychiatry. Where do they overlap? UR - ://WOS:000274143900005 VL - 158 ID - 2576 ER - TY - JOUR AB - Several important longitudinal studies in the social sciences have omitted biomarkers that are routinely, recorded today, including height and weight. To account for this shortcoming in the Wisconsin Longitudinal Study (WLS). an 11-point scale was developed to code high school senior class yearbook photographs of WLS participants for relative body, mass (RBM). Our analyses show, that although imperfect. the RBM scale is reliable (alpha (sic) 91) and meets several criteria of validity as a measure of body mass. Measured at ages 17 18, the standardized relative body mass index (SRBMI) was moderately correlated (r=31) with body index (BMI) at ages 53 54 and with maximum BMI reported between ages 16 and 30 (r = 48). Overweight adolescents (>= 90th percentile of SRBMI) were about three times more likely than healthy-weight adolescents (10th 80th percentile of SRBMI) to be obese in adulthood and, as a likely, significantly more likely to report health problems such as; chest pain and diabetes. Overweight adolescents also suffered a twofold risk of premature death from all nonaccidental causes as well as a fourfold risk of heart disease mortality. The RBM scale has removed a serious obstacle to obesity research and lifelong analysis of health in the WLS. We suggest that other longitudinal studies may, also he able to obtain photos of participants at younger ages and thus gain a prospectively useful substitute for direct measures of body mass. AN - WOS:000263847900002 AU - Reither, E. N. AU - Hauser, R. M. AU - Swallen, K. C. DA - Feb DO - 10.1353/dem.0.0037 IS - 1 N1 - Reither, Eric N. Hauser, Robert M. Swallen, Karen C. 1533-7790 PY - 2009 SN - 0070-3370 SP - 27-41 ST - PREDICTING ADULT HEALTH AND MORTALITY FROM ADOLESCENT FACIAL CHARACTERISTICS IN YEARBOOK PHOTOGRAPHS T2 - Demography TI - PREDICTING ADULT HEALTH AND MORTALITY FROM ADOLESCENT FACIAL CHARACTERISTICS IN YEARBOOK PHOTOGRAPHS UR - ://WOS:000263847900002 VL - 46 ID - 2616 ER - TY - JOUR AB - OBJECTIVES: To measure the change in health-related quality of life (HRQOL) before and after gynaecologic surgery and to compare HRQOL to age-matched Canadian normative data. METHODS: This prospective observational cohort study consisted of a convenience sample of 460 women scheduled for elective gynaecologic surgery. Women underwent surgery for a variety of reasons, including cancer, menorrhagia/dysfunctional uterine bleeding, benign uterine masses, prolapse or urinary incontinence, and chronic pelvic pain syndromes. Women were recruited preoperatively and followed for six months after surgery. HRQOL questionnaires were completed preoperatively and at six weeks and six months postoperatively, using the SF-36, and compared between time points and against normative data. Analysis included univariate statistics, repeated measures ANOVA, paired t tests, and independent samples t tests. RESULTS: The mean age of women in the study cohort was 49 years (± 11); the majority were married, employed, had an education beyond high school, were overweight or obese, had a hysterectomy, and had an abdominal incision. Twenty-eight percent underwent surgery for cancer. General and mental health domains showed significant improvement between the preoperative and six-week postoperative assessments, while the remaining domains showed statistically significant declines. All but one (general health) of 10 outcomes saw significant improvements from the preoperative to the six-month follow-up assessment. Preoperatively, the surgical sample scored worse on all but one (role emotional) outcome than the normative data. By six months, domain scores were much closer to normative values. CONCLUSION: Health-related quality of life improved considerably from the preoperative period to six months postoperative in women who underwent gynaecologic surgery. When compared with normative data from age-matched women, the surgical sample reported significantly reduced HRQOL preoperatively and at six weeks following surgery, but by six months after surgery HRQOL had rebounded to the point of being comparable to age-matched peers. AD - Department of Anesthesiology and Perioperative Medicine, Queen's University, Kingston ON. AN - 22166278 AU - Reitsma, M. L. AU - Vandenkerkhof, E. G. AU - Johnston, S. L. AU - Hopman, W. M. DA - Dec DO - 10.1016/s1701-2163(16)35109-x DP - NLM ET - 2011/12/15 IS - 12 KW - Adult Canada Cohort Studies Elective Surgical Procedures Female *Gynecologic Surgical Procedures *Health Status Humans Middle Aged Patient Satisfaction Postoperative Period Preoperative Period Prospective Studies *Quality of Life Surveys and Questionnaires LA - eng N1 - Reitsma, Michelle L Vandenkerkhof, Elizabeth G Johnston, Shawna L Hopman, Wilma M Canadian Institutes of Health Research/Canada Journal Article Research Support, Non-U.S. Gov't Netherlands J Obstet Gynaecol Can. 2011 Dec;33(12):1241-7. doi: 10.1016/s1701-2163(16)35109-x. PY - 2011 SN - 1701-2163 (Print) 1701-2163 SP - 1241-7 ST - Does health-related quality of life improve in women following gynaecological surgery? T2 - J Obstet Gynaecol Can TI - Does health-related quality of life improve in women following gynaecological surgery? VL - 33 ID - 4206 ER - TY - JOUR AB - AIM: To determine prevalence of irritable bowel syndrome (IBS) and associated factors in a community-based population of adolescents. MATERIAL AND METHODS: 189 schoolboys and 250 schoolgirls aged 14-17 years from four randomly chosen schools of Novosibirsk participated in the study. RESULTS: The prevalence of IBS defined according to Rome criteria was higher in girls (24 vs 14% in boys, p = 0.01). Colonic pain frequency was similar in both genders (11% in girls vs 9% in boys, p = 0.46), however disturbed defecation occurred significantly more often in girls than in boys (16 vs 7%, p = 0.003). Half of the subjects who reported IBS had also dyspeptic symptoms. Fiber-rich diet and/or laxatives to prevent constipation were used by 2% of boys and 7% of girls (p = 0.012). However, only one third of those having less than 3 stools a week thought it abnormal. IBS is associated with the age over 15-16 years, female gender, abdominal pain in childhood, appendectomy, irregular meals and smoking (in girls). No association was found with other socio-demographic factors and serological markers of some infections and invasions (H. pylori, G. lamblia, O. felineus, hepatitis viruses B and C). Of the persons with diagnosable IBS, 49% have consulted a physician about it, 21% have undergone upper endoscopy. School absenteeism was reported by 62% of the IBS sufferers. CONCLUSION: IBS is common among adolescents (especially girls) with the prevalence rates similar to those described in adults from West Europe and USA. These disorders are associated with significant disability and health care costs. AN - 11338849 AU - Reshetnikov, O. V. AU - Kurilovich, S. A. AU - Denisova, D. V. AU - Zav'ialova, L. G. AU - Svetlova, I. O. AU - Tereshonok, I. N. AU - Krivenchuk, N. A. AU - Eremeeva, L. I. DP - NLM ET - 2001/05/08 IS - 2 KW - Adolescent Age Factors Colonic Diseases, Functional/diagnosis/*epidemiology/etiology Cross-Sectional Studies Female Humans Male Risk Factors Sex Factors Siberia/epidemiology LA - rus N1 - Reshetnikov, O V Kurilovich, S A Denisova, D V Zav'ialova, L G Svetlova, I O Tereshonok, I N Krivenchuk, N A Eremeeva, L I Comparative Study English Abstract Journal Article Russia (Federation) Ter Arkh. 2001;73(2):24-9. OP - Rasprostranennost' i faktory riska razvitiia sindroma razdrazhennogo kishechnika u podrostkov: populiatsionnoe issledovanie. PY - 2001 SN - 0040-3660 (Print) 0040-3660 SP - 24-9 ST - [Prevalence and risk factors of the development of irritable bowel syndrome in adolescents: a population study] T2 - Ter Arkh TI - [Prevalence and risk factors of the development of irritable bowel syndrome in adolescents: a population study] VL - 73 ID - 3972 ER - TY - JOUR AB - Aim. To determine prevalence of irritable bowel syndrome (IBS) and associated factors in a community-based population of adolescents. Material and methods. 189 schoolboys and 250 schoolgirls aged 14-17 years front four randomly chosen schools of Novosibirsk participated in the study. Results. The prevalence of IBS defined according to Rome criteria was higher in girls (24 vs 14% in boys, p = 0.01). Colonic pain frequency was similar in both genders (11% in girls vs 9% in boys, p = 0.46), however disturbed defecation occurred significantly more often in girls than in boys (16 vs 7%, p = 0.003). Half of the subjects who reported IBS had also dyspeptic symptoms. Fiber-rich diet and/or laxatives to prevent constipation were used by 2% of boys and 7% of girls (p = 0.012). However, only one third of those having less than 3 stools a week thought it abnormal. IBS is associated with the age over 15-16 years, female gender, abdominal pain in childhood, appendectomy, irregular meals and smoking (in girls). No association was found with other socio-demographic factors and serological markers of some infections and invasions (H. pylori, G. lamblia, O. felineus, hepatitis viruses B and C). Of the persons with diagnosable IBS, 49% have consulted a physician about it, 21% have undergone upper endoscopy. School absenteeism was reported by 62% of the IBS sufferers. Conclusion. IBS is common among adolescents (especially girls) with the prevalence rates similar to those described in adults front West Europe and USA. These disorders are associated with significant disability and health care costs. AN - WOS:000170937200007 AU - Reshetnikov, O. V. AU - Kurilovich, S. A. AU - Denisova, D. V. AU - Zavyalova, L. G. AU - Svetlova, I. O. AU - Tereshonok, I. N. AU - Krivenchuk, N. A. AU - Eremeeva, L. I. IS - 2 N1 - Reshetnikov, OV Kurilovich, SA Denisova, DV Zavyalova, LG Svetlova, IO Tereshonok, IN Krivenchuk, NA Eremeeva, LI Zavyalova, Larisa/R-4852-2017 PY - 2001 SN - 0040-3660 SP - 24-29 ST - Prevalence of and risk factors for irritable bowel syndrome in adolescents: Population-based study T2 - Terapevticheskii Arkhiv TI - Prevalence of and risk factors for irritable bowel syndrome in adolescents: Population-based study UR - ://WOS:000170937200007 VL - 73 ID - 2861 ER - TY - JOUR AB - Aim. To study the prevalence and risk factors for dyspepsia and gastroesophageal reflux (GER) among adolescents. Material and methods. Senior schoolchildren (forms 9-11) of four randomly selected secondary schools of Novosibirsk participated in the study (189 boys and 260 girls aged 14-17 years). They, filled in the Bowel Disease Questionnaire, and sera were tested for antibodies against Helicobacter pylori infection. Results. Dyspepsia was reported by 21% of the schoolchildren, being more frequent in girls (25%) than boys (14516, p = 0,004). GER occurred in 22% of adolescents with the same frequency in both genders. The combination of dyspepsia with GER was found in 8%. The prevalence of H pylori infection was 56%. No association was found between the infection and abdominal symptoms, except heartburn. Among factors associated with dyspepsia were female gender, Irregular Meals, family history, of dyspepsia. GER was related to H. pylori infection, obesity, smoking and irregular meals. 46% of adolescents with dyspepsia and 36% of those with GER have consulted a physician, and school absenteeism was reported by 55 and 40%, respectively. Conclusion. Dyspepsia and gastroesophageal reflux are widespread among the adolescent population and result in frequent use of health care resourses. AN - WOS:000175334800002 AU - Reshetnikov, O. V. AU - Kurilovich, S. A. AU - Tereshonok, I. N. AU - Denisova, D. V. AU - Zavyalova, L. G. AU - Krivenchuk, N. A. AU - Zimina, I. Y. AU - Granberg, C. AU - Haiva, V. M. IS - 2 N1 - Reshetnikov, OV Kurilovich, SA Tereshonok, IN Denisova, DV Zavyalova, LG Krivenchuk, NA Zimina, IY Granberg, C Haiva, VM Zavyalova, Larisa/R-4852-2017 PY - 2002 SN - 0040-3660 SP - 9-13 ST - Dyspepsia and gastroesophageal reflux in adolescents T2 - Terapevticheskii Arkhiv TI - Dyspepsia and gastroesophageal reflux in adolescents UR - ://WOS:000175334800002 VL - 74 ID - 2843 ER - TY - JOUR AB - The mental health problems among adolescents have long-lasting effects throughout life. However, research evidence indicates that only 10-30% of adolescents who needed mental health care had received specialized help. The present study reports the prevalence of mental health problems and help-seeking among adolescents, taking into account gender and age differences. The sample included 1752 adolescents (47 boys,) aged 12-17 years. Data were collected on in two Siberian cities (Novosibirsk and Krasnoyarsk) using an international self-report questionnaire developed for the school-based Eurasian Child Mental Health Study. Participants were recruited from 18 schools, students completed questionnaires anonymously during school lessons. Statistical analysis included analysis of variance (ANOVA), multiple regression analysis, and crosstabs using a chi-squared test. The level of emotional and behavioral problems in Siberian adolescents was slightly higher than that found in European and Asian countries. Twenty three percent of adolescents reported frequent headaches (at least once a week), 11 % reported frequent abdominal pain and 14% suffered from frequent sleep disturbances (3-5 times a week or more). Girls reported a significantly higher level of problems than boys, with the largest gender differences for emotional problems, recurrent pains and sleep disturbances. Weekly consumption of alcohol and daily use of nicotine among boys was more common than among girls (3 % and 6 %, respectively), whereas less frequent use of alcohol and nicotine was commoner in girls (16 %) than in boys (10 %); 7 % of boys and girls had tried drugs at least once. Suicidal thoughts were reported by 22 % of adolescents, 6 % reported suicide attempts and 6 % reported repeated self-harm. One third of adolescents considered seeking outside help and 9 % had actually done so. Girls reported more help-seeking than boys; older girls sought help more often than younger and middle-aged ones. Around one third of adolescents sought help from their relatives; 26 % from friends, the Internet or other non-professional sources; 5 % reported seeking help from a doctor or nurse, and 3 % from a psychologist. The most important independent predictors of seeking help were emotional symptoms, suicidal ideation and hyperactivity/inattention. The results suggest a need for future investigation of the factors associated with help-seeking behavior among adolescents. It is also necessary to develop mental health promotion programs for adolescents, interventions to improve mental health literacy and access to mental health care. AN - WOS:000635181500011 AU - Rezun, E. V. AU - Slobodskaya, H. R. AU - Semenova, N. B. AU - Rippinen, T. O. DA - Mar DO - 10.17223/17267080/79/11 IS - 79 N1 - Rezun, E., V Slobodskaya, H. R. Semenova, N. B. Rippinen, T. O. 2411-0809 PY - 2021 SN - 1726-7080 SP - 189-202 ST - Mental Health Problems and Help-Seeking among Adolescents T2 - Sibirskiy Psikhologicheskiy Zhurnal-Siberian Journal of Psychology TI - Mental Health Problems and Help-Seeking among Adolescents UR - ://WOS:000635181500011 ID - 1751 ER - TY - JOUR AB - This study was conducted to establish race/ethnic-specific prevalence for 10 physical symptoms in American youths and to examine the extent to which socioeconomic status and depressive symptoms explained racial differences in those symptoms. This descriptive study was based on a cross-sectional analysis of survey data from Wave I of the National Longitudinal Study of Adolescent Health including a school-based sample of over 20,000 adolescents in Grades 7 through 12. Self-reported physical symptoms during the past 12 months were examined. White youths reported the highest frequency of headaches, musculoskeletal pain, and dizziness; feeling hot, chest pain, cold sweats, and urinary symptoms were more common in Black youths. The three symptoms reported by Whites remained significant after controlling for family income and depressive symptoms, whereas racial differences in the four symptoms prominent in Blacks were accounted for by family income and depressive symptoms. Findings highlight racial differences in symptom types and in psychosocial factors contributing to physical symptoms in adolescents and warn against health-care providers' stereotyping associations between physical symptoms and socioeconomic status. AD - Department of Family, Community and Mental Health Systems, University of Virginia, School of Nursing, Charlottesville, VA 22908, USA. hrk3@virginia.edu AN - 15933649 AU - Rhee, H. DA - Jun DO - 10.1016/j.pedn.2005.01.003 DP - NLM ET - 2005/06/04 IS - 3 KW - Adolescent African Americans/ethnology/genetics/*statistics & numerical data Chest Pain/ethnology Cough/ethnology Cross-Cultural Comparison Cross-Sectional Studies Depression/ethnology Dizziness/ethnology European Continental Ancestry Group/ethnology/genetics/*statistics & numerical data Fatigue/ethnology Female Headache/ethnology *Health Status Health Surveys Humans Male Models, Statistical Pain/ethnology Pharyngitis/ethnology Prevalence Recurrence Socioeconomic Factors United States/epidemiology Urination Disorders/ethnology LA - eng N1 - Rhee, Hyekyun P01-HD31921/HD/NICHD NIH HHS/United States Comparative Study Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. United States J Pediatr Nurs. 2005 Jun;20(3):153-62. doi: 10.1016/j.pedn.2005.01.003. PY - 2005 SN - 0882-5963 (Print) 0882-5963 SP - 153-62 ST - Racial/ethnic differences in adolescents' physical symptoms T2 - J Pediatr Nurs TI - Racial/ethnic differences in adolescents' physical symptoms VL - 20 ID - 3363 ER - TY - JOUR AB - Headache is a frequent neurological symptom in children and adolescents. Recurrent headaches have a significant disabling effect, with consequences including school absenteeism, decreased participation in extracurricular activities, and poor academic performance, and are a risk factor for further chronic headaches and other pain syndromes that merit increased attention. The most common types of primary headache in children and adolescents are migraine and tension-type headache (TTH). In a recent survey of South Korean school students, 29.1% of schoolchildren reported having recurrent headaches. TTH was more frequent than recurrent migraine headaches (13.7% vs. 8.7%), and the frequency of migraine and TTH increased with age. The prevalence rate of TTH in urban areas was higher than in suburban and rural areas. A trend was found for more severe disabilities to occur in older children with headache. Children and adolescents with migraine had the most severe headache-related disabilities. The predictors of headache-related disability were found to be migraine, severe intensity of the headache, frequent headache, and a longer duration of symptoms before presentation. Children and adolescents with recurrent or significant headaches should be diagnosed and treated promptly to reduce headache-related disability and to improve their quality of life. AN - WOS:000397260400003 AU - Rho, Y. I. DA - Feb DO - 10.5124/jkma.2017.60.2.112 IS - 2 N1 - Rho, Young-Il Rho, Youngil/0000-0002-5382-3153 2093-5951 PY - 2017 SN - 1975-8456 SP - 112-117 ST - Prevalence of headache and headache-related disability in children and adolescents T2 - Journal of the Korean Medical Association TI - Prevalence of headache and headache-related disability in children and adolescents UR - ://WOS:000397260400003 VL - 60 ID - 2110 ER - TY - JOUR AB - BACKGROUND: Paediatric data on the association between diagnostic delay and inflammatory bowel disease [IBD] complications are lacking. We aimed to determine the effect of diagnostic delay on stricturing/fistulising complications, surgery, and growth impairment in a large paediatric cohort, and to identify predictors of diagnostic delay. METHODS: We conducted a national, prospective, multicentre IBD inception cohort study including 1399 children. Diagnostic delay was defined as time from symptom onset to diagnosis >75th percentile. Multivariable proportional hazards [PH] regression was used to examine the association between diagnostic delay and stricturing/fistulising complications and surgery, and multivariable linear regression to examine the association between diagnostic delay and growth. Predictors of diagnostic delay were identified using Cox PH regression. RESULTS: Overall (64% Crohn's disease [CD]; 36% ulcerative colitis/IBD unclassified [UC/IBD-U]; 57% male]), median time to diagnosis was 4.2 (interquartile range [IQR] 2.0-9.2) months. For the overall cohort, diagnostic delay was >9.2 months; in CD, >10.8 months and in UC/IBD-U, >6.6 months. In CD, diagnostic delay was associated with a 2.5-fold higher rate of strictures/internal fistulae (hazard ratio [HR] 2.53, 95% confidence interval [CI] 1.41-4.56). Every additional month of diagnostic delay was associated with a decrease in height-for-age z-score of 0.013 standard deviations [95% CI 0.005-0.021]. Associations persisted after adjusting for disease location and therapy. No independent association was observed between diagnostic delay and surgery in CD or UC/IBD-U. Diagnostic delay was more common in CD, particularly small bowel CD. Abdominal pain, including isolated abdominal pain in CD, was associated with diagnostic delay. CONCLUSIONS: Diagnostic delay represents a risk factor for stricturing/internal fistulising complications and growth impairment in paediatric CD. PODCAST: This article has an associated podcast which can be accessed at https://academic.oup.com/ecco-jcc/pages/podcast. AD - SickKids Hospital, University of Toronto, Toronto, ON, Canada. Children's Hospital of Eastern Ontario [CHEO], Inflammatory Bowel Disease Centre, Ottawa, ON, Canada. Stollery Children's Hospital, University of Alberta, Edmonton, AB, Canada. B.C. Children's Hospital, Vancouver, BC, Canada. IWK Health Centre, Halifax, NS, Canada. Alberta Children's Hospital, University of Calgary, Calgary, AB, Canada. Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada. CHU Sainte-Justine, Montreal, QC, Canada. McMaster Children's Hospital, Hamilton, ON, Canada. Janeway Children's Health and Rehabilitation Centre, St. John's, NL, Canada. Children's Hospital of Western Ontario, London, ON, Canada. Montreal Children's Hospital, Montreal, QC, Canada. CHEO Research Institute, Ottawa, ON, Canada. Department of Pediatrics and School of Epidemiology and Public Health, University of Ottawa, Ottawa, ON, Canada. ICES uOttawa, Ottawa, ON, Canada. AN - 32978629 AU - Ricciuto, A. AU - Mack, D. R. AU - Huynh, H. Q. AU - Jacobson, K. AU - Otley, A. R. AU - deBruyn, J. AU - El-Matary, W. AU - Deslandres, C. AU - Sherlock, M. E. AU - Critch, J. N. AU - Bax, K. AU - Jantchou, P. AU - Seidman, E. G. AU - Carman, N. AU - Rashid, M. AU - Muise, A. AU - Wine, E. AU - Carroll, M. W. AU - Lawrence, S. AU - Van Limbergen, J. AU - Benchimol, E. I. AU - Walters, T. D. AU - Griffiths, A. M. AU - Church, P. C. C2 - PMC7944510 DA - Mar 5 DO - 10.1093/ecco-jcc/jjaa197 DP - NLM ET - 2020/09/27 IS - 3 KW - Inflammatory bowel disease [IBD] fistula stricture LA - eng N1 - 1876-4479 Ricciuto, Amanda Mack, David R Huynh, Hien Q Jacobson, Kevan Otley, Anthony R deBruyn, Jennifer El-Matary, Wael Deslandres, Colette Sherlock, Mary E Critch, Jeffrey N Bax, Kevin Jantchou, Prevost Seidman, Ernest G Carman, Nicholas Rashid, Mohsin Muise, Aleixo Wine, Eytan Carroll, Matthew W Lawrence, Sally Van Limbergen, Johan Benchimol, Eric I Walters, Thomas D Griffiths, Anne M Church, Peter C RC2 DK118640/DK/NIDDK NIH HHS/United States Journal Article J Crohns Colitis. 2021 Mar 5;15(3):419-431. doi: 10.1093/ecco-jcc/jjaa197. PY - 2021 SN - 1873-9946 (Print) 1873-9946 SP - 419-431 ST - Diagnostic Delay Is Associated With Complicated Disease and Growth Impairment in Paediatric Crohn's Disease T2 - J Crohns Colitis TI - Diagnostic Delay Is Associated With Complicated Disease and Growth Impairment in Paediatric Crohn's Disease VL - 15 ID - 4194 ER - TY - JOUR AB - Children with acute recurrent and chronic pancreatitis experience severe abdominal pain that may be intermittent or chronic. Pain is often debilitating, causing interference with academic, social, family, and extracurricular activities that are important to youth. Disruption of these routines and the unpredictability of pain flares place children with pancreatitis at increased risk for development of anxious or depressive symptoms. Pediatric psychologists trained in cognitive-behavioral treatment are well suited to intervene on functional disability and mood disturbance, as well as teach coping skills. In an era where there is movement away from opioids, nonpharmacological strategies have an important place for pain management. In fact, positive outcomes following for children with other recurrent abdominal pain syndromes have been reported for this evidence-based intervention. In addition to pain management, pediatric psychologists can address other co-occurring behavioral and emotional problems in children with pancreatitis, such as needle phobia and poor adherence to the prescribed medical regimen. AN - WOS:000553345100009 AU - Rich, K. L. AU - Abu-El-Haija, M. AU - Nathan, J. D. AU - Lynch-Jordan, A. DA - Aug DO - 10.1097/mpa.0000000000001598 IS - 7 N1 - Rich, Kristin Loiselle Abu-El-Haija, Maisam Nathan, Jaimie D. Lynch-Jordan, Anne 1536-4828 PY - 2020 SN - 0885-3177 SP - 887-890 ST - The Role of Psychology in the Care of Children With Pancreatitis T2 - Pancreas TI - The Role of Psychology in the Care of Children With Pancreatitis UR - ://WOS:000553345100009 VL - 49 ID - 1806 ER - TY - JOUR AB - OBJECTIVES: To (1) determine the efficacy of venlafaxine XR for the treatment of pain (secondary aim) in individuals with spinal cord injury (SCI) enrolled in a randomized controlled trial (RCT) on the efficacy of venlafaxine XR for major depressive disorder (MDD) (primary aim); and (2) test the hypothesis that venlafaxine XR would be effective for both neuropathic and nociceptive pain. DESIGN: Multisite, double-blind, randomized (1:1) controlled trial with subjects block randomized and stratified by site, lifetime history of substance abuse, and prior history of MDD. SETTING: Six Departments of Physical Medicine and Rehabilitation in university-based medical schools. PARTICIPANTS: Individuals (N=123) with SCI and major depression between 18 and 64 years of age, at least 1 month post-SCI who also reported pain. INTERVENTION: Twelve-week trial of venlafaxine XR versus placebo using a flexible titration schedule. OUTCOME MEASURES: A 0-to-10 numeric rating scale for pain, pain interference items of the Brief Pain Inventory; 30% and 50% responders. RESULTS: The effect of venlafaxine XR on neuropathic pain was similar to that of placebo. However venlafaxine XR resulted in statistically significant and clinically meaningful reductions in nociceptive pain site intensity and interference even after controlling for anxiety, depression, and multiple pain sites within the same individual. For those who achieved a minimally effective dose of venlafaxine XR, some additional evidence of effectiveness was noted for those with mixed (both neuropathic and nociceptive) pain sites. CONCLUSIONS: Venlafaxine XR could complement current medications and procedures for treating pain after SCI and MDD that has nociceptive features. Its usefulness for treating central neuropathic pain is likely to be limited. Research is needed to replicate these findings and determine whether the antinociceptive effect of venlafaxine XR generalizes to persons with SCI pain without MDD. AD - Department of Physical Medicine and Rehabilitation, University of Alabama at Birmingham, Birmingham, AL. Electronic address: Richards@uab.edu. Department of Rehabilitation Medicine, University of Washington, Seattle, WA. Feinberg School of Medicine, Northwestern University, Chicago, IL; James A. Haley Veterans Hospital, Tampa, FL. Department of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI. Department of Rehabilitation Medicine, University of Miami, Coral Gables, FL. Department of Neurological Surgery, University of Washington, Seattle, WA. Feinberg School of Medicine, Northwestern University, Chicago, IL. Department of Psychiatry and Behavioral Neurobiology, University of Cincinnati, Cincinnati, OH. Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA. AN - 25527253 AU - Richards, J. S. AU - Bombardier, C. H. AU - Wilson, C. S. AU - Chiodo, A. E. AU - Brooks, L. AU - Tate, D. G. AU - Temkin, N. R. AU - Barber, J. K. AU - Heinemann, A. W. AU - McCullumsmith, C. AU - Fann, J. R. DA - Apr DO - 10.1016/j.apmr.2014.11.024 DP - NLM ET - 2014/12/21 IS - 4 KW - Adolescent Adult Cyclohexanols/administration & dosage/adverse effects/*therapeutic use Delayed-Action Preparations Depressive Disorder, Major/*drug therapy/*epidemiology Double-Blind Method Female Humans Male Medication Adherence Middle Aged Neuralgia/drug therapy/epidemiology Nociceptive Pain/drug therapy/epidemiology Pain/drug therapy/*epidemiology Psychiatric Status Rating Scales Spinal Cord Injuries/*epidemiology Trauma Severity Indices Venlafaxine Hydrochloride Young Adult Antidepressive agents Pain Rehabilitation Spinal cord injuries Venlafaxine LA - eng N1 - 1532-821x Richards, J Scott Bombardier, Charles H Wilson, Catherine S Chiodo, Anthony E Brooks, Larry Tate, Denise G Temkin, Nancy R Barber, Jason K Heinemann, Allen W McCullumsmith, Cheryl Fann, Jesse R Journal Article Multicenter Study Randomized Controlled Trial Research Support, U.S. Gov't, Non-P.H.S. United States Arch Phys Med Rehabil. 2015 Apr;96(4):680-9. doi: 10.1016/j.apmr.2014.11.024. Epub 2014 Dec 17. PY - 2015 SN - 0003-9993 SP - 680-9 ST - Efficacy of venlafaxine XR for the treatment of pain in patients with spinal cord injury and major depression: a randomized, controlled trial T2 - Arch Phys Med Rehabil TI - Efficacy of venlafaxine XR for the treatment of pain in patients with spinal cord injury and major depression: a randomized, controlled trial VL - 96 ID - 3663 ER - TY - JOUR AB - Headaches are a frequent health problem among children and adolescents. The ocurrence of headaches and the resulting impairments in the quality of life and activities of daily living are modulated by biopsychosocial interactions, which necessitate a complex treatment program. The Dresden Childrens Headache Program (DreKiP) is a multidisciplinary therapy program consisting of eight modules for children and adolescents: education, stress relief, relaxation techniques, physical fitness, climbing therapy, art therapy and sensory training. In addition, there are six modules containing parallel workshops for parents. This outpatient program lasts 2-3 months and is performed parallel to the daily and school routine. Therapy groups consist of 6-8 patients in each age group. In total patients receive 15 h and the parents 7 h of therapy. Concomitant with the program, headache-associated data, such as headache frequency, medication use and school absence are documented. So far 32 children and adolescents in groups of 11, 14-15, 14-16, 17and 17-18 years old completed the program. Of the 32 patients 19 presented with migraine and tension type headache, 6/32 with migraine and 7/32 with tension type headache only. The median number of headache days was 15 per month and 4 official school absence days per month. Preliminary results 6 months after the end of the therapy program showed reduced frequency of headaches in three quarters of our patients. The headache frequency was reduced from an initial median of 15 days per month to a median of 8 days per month after the program. The multidisciplinary program DreKiP improves the use of therapeutic means in children and adolescents with primary headaches. Children and adolescents with headache-related impairment in activities of daily life in school and leisure times constitute the target group of this therapy. AN - WOS:000425731800004 AU - Richter, M. AU - Gruhl, E. AU - Lautenschlager, E. AU - Muller, T. AU - Schumann, F. AU - Skiera, D. AU - Theisinger, A. AU - Zimmer, U. AU - Berner, R. AU - von der Hagen, M. AU - Sabatowski, R. AU - Hahner, A. AU - Gossrau, G. DA - Feb DO - 10.1007/s00482-017-0245-7 IS - 1 N1 - Richter, M. Gruhl, E. Lautenschlaeger, E. Mueller, T. Schumann, F. Skiera, D. Theisinger, A. Zimmer, U. Berner, R. von der Hagen, M. Sabatowski, R. Haehner, A. Gossrau, G. Sabatowski, Rainer/K-3475-2019; Berner, Reinhard/P-7351-2017 Sabatowski, Rainer/0000-0003-2228-3147; Berner, Reinhard/0000-0002-6216-9173 1432-2129 PY - 2018 SN - 0932-433X SP - 17-29 ST - DreKiP - an outpatient treatment program for children and adolescents with headache T2 - Schmerz TI - DreKiP - an outpatient treatment program for children and adolescents with headache UR - ://WOS:000425731800004 VL - 32 ID - 2035 ER - TY - JOUR AB - Juvenile pain amplification syndromes show an increasing incidence. Around 10% of the paediatric rheumatological outpatients have pain amplification syndromes. The patients suffer under intensive musculoskeletal pain without a somatic correlate. The disease is, due to the desocialisation of patients, a challenge for the therapists. A multidisciplinary activating team approach focuses on the bio-psycho-social model of chronic pain. The pain leads the patients into social retreat, which begins with a reduction of activity by missing the regular school sport lessons. Since sport has bio-psycho-social aspects as well, it can be used therapeutically in chronic pain patients, can influence the cause of disease positively and also allows access to prognostic information. The aim should be to integrate sport as an important module into the multimodal treatment and to use the defocusing aspects of sport and the joy of movement therapeutically. This helps the patients to reintegrate into daily live and motivates them towards an activating therapy, which they can continue on their own. AN - WOS:000254192400002 AU - Richter, M. AU - Hafner, R. AU - Michels, H. DO - 10.1055/s-2008-1027170 IS - 1 N1 - Richter, M. Haefner, R. Michels, H. 1438-9940 PY - 2008 SN - 0341-051X SP - 17-21 ST - Sport and its importance for juvenile pain amplification syndromes T2 - Aktuelle Rheumatologie TI - Sport and its importance for juvenile pain amplification syndromes UR - ://WOS:000254192400002 VL - 33 ID - 2666 ER - TY - JOUR AB - Barely any available treatment is effective in children and adolescents with chronic musculoskeletal pain. The increasing number of these patients motivated us to develop our own therapeutic concept. It is a multidisciplinary approach consisting of medical advice and care, psychological counseling in individual and group settings, physiotherapy with fitness training and occupational therapy as well as therapeutic activities as part of adventure exercises. Drug therapy plays a limited role since it has been proven inefficient in most patients. Any adjuvant therapy should consider analgesics on demand and, for a few severely adamant cases, antidepressants or serotonin reuptake inhibitors. Our preliminary results are promising. The therapy increases the self-confidence in children and adolescents. We could often improve social interactions, reduce absenteeism from school and encourage leisure activities. Frequently but not invariably, this was associated with a significant reduction in pain intensity. AN - WOS:000222664400009 AU - Richter, M. AU - Hafner, R. AU - Schurer, A. AU - Spamer, M. AU - Fischer, K. AU - Fauser, B. DA - Jun DO - 10.1055/s-2004-813303 IS - 3 N1 - Richter, M Hafner, R Schurer, A Spamer, M Fischer, K Fauser, B PY - 2004 SN - 0341-051X SP - 158-163 ST - The Garmisch model for treating pain in pediatric and adolescent rheumatology T2 - Aktuelle Rheumatologie TI - The Garmisch model for treating pain in pediatric and adolescent rheumatology UR - ://WOS:000222664400009 VL - 29 ID - 2793 ER - TY - JOUR AB - When pediatric pain is refractory and unresponsive to appropriate use of analgesic agents, there might be additional physical or psychologic dimensions of the pain that are not addressed by the analgesics. In addition to appropriate analgesic therapy, the psychologic needs of the child should be directly addressed and appropriate adjunctive physical modalities employed. Although benzodiazepines lack direct analgesic effects, they can reduce the distress associated with acute pain states by decreasing anxiety, insomnia, and muscle spasms that can be associated with acute pain. Intermediate or long-acting benzodiazepines in modest doses can be useful adjunctive agents when used short term for the treatment of selected acute pain complaints. In the highly distressed school-age child or adolescent with pain complaints relatively unresponsive to appropriate care, judicious use of benzodiazepines is worthy of consideration. AN - 1287112 AU - Richtsmeier, A. J. AU - Barkin, R. L. AU - Alexander, M. DA - Nov DO - 10.1016/0885-3924(92)90136-6 DP - NLM ET - 1992/11/01 IS - 8 KW - Acute Disease Adolescent Benzodiazepines/pharmacology/*therapeutic use Child Female Humans Male Pain/diagnosis/*drug therapy LA - eng N1 - Richtsmeier, A J Barkin, R L Alexander, M Case Reports Journal Article United States J Pain Symptom Manage. 1992 Nov;7(8):492-5. doi: 10.1016/0885-3924(92)90136-6. PY - 1992 SN - 0885-3924 (Print) 0885-3924 SP - 492-5 ST - Benzodiazepines for acute pain in children T2 - J Pain Symptom Manage TI - Benzodiazepines for acute pain in children VL - 7 ID - 3854 ER - TY - JOUR AB - The efficacy of a multidisciplinary approach for the treatment of chronic pain has been well documented. A recent randomized prospective trial by Peters and co-workers confirmed that multidisciplinary management of chronic pelvic pain resulted in greater improvement in pain severity, increased employment, and improved functional health scores when compared with a traditional medical approach. Unfortunately, many gynecologists do not have the luxury of working in these types of settings. The SAFE approach allows the busy practitioner to evaluate the nonorganic and organic nature of pelvic pain simultaneously to manage these difficult patients better. Initially, it is important to set up regular weekly visits with a prespecified time limit. During these sessions, one should focus on compliance to treatment recommendations. Components of management that have led to pain reduction should be defined. Over time, these short visits can be spaced to bimonthly and monthly intervals; however, this strategy should not be rushed. If possible, the gynecologist should coordinate the care of difficult patients with a physical therapist and mental health provider who can work in tandem on pain reduction strategies and focused psychotherapy. The gynecologist should focus the patient's attention on improvements in pain reports and in functioning at school or work and reinforce the consistent use of medications, even if the recommended dose is low. Small improvements in health beget larger improvements in daily functioning. AD - Department of Pediatrics, Mount Sinai School of Medicine, Mount Sinai Hospital-NYU Health, New York, USA. vaughn_rickert@smtplink.mssm.edu AN - 10693189 AU - Rickert, V. I. AU - Kozlowski, K. J. DA - Mar DO - 10.1016/s0889-8545(00)80013-3 DP - NLM ET - 2000/02/29 IS - 1 KW - Adnexal Diseases Adolescent Adult Endometriosis/diagnosis Female Humans Pelvic Inflammatory Disease/diagnosis Pelvic Pain/*etiology Pregnancy Torsion Abnormality LA - eng N1 - Rickert, V I Kozlowski, K J Journal Article Review United States Obstet Gynecol Clin North Am. 2000 Mar;27(1):181-93. doi: 10.1016/s0889-8545(00)80013-3. PY - 2000 SN - 0889-8545 (Print) 0889-8545 SP - 181-93 ST - Pelvic pain. A SAFE approach T2 - Obstet Gynecol Clin North Am TI - Pelvic pain. A SAFE approach VL - 27 ID - 4069 ER - TY - JOUR AB - OBJECTIVES: Back pain afflicts approximately 31 million Americans, and is the number one cause of activity limitation in young adults. Little is known about the labor productivity costs associated with this chronic disease. Such information could provide useful input to employers considering alternative health benefits plans for managing their employees' health care needs. The goals of this study were to generate employee-level as well as national estimates of the labor productivity losses associated with chronic back ache. METHODS: Multivariate methods were used to isolate the effects of chronic backache on employment status and disability days. These results were combined with information on earnings to generate labor productivity cost estimates associated with chronic backache. The study used data from the National Medical Care Expenditure Survey (NMES), which provides information on health status, health care utilization and cost, work, disability, and sociodemographic characteristics for a nationally representative sample of the noninstitutionalized civilian population of the United States in 1987. RESULTS: Average annual productivity losses per worker due to chronic backache were $1,230 for male workers, measured in 1996 dollars, and $773 per female worker. These figures translated into aggregate annual productivity losses from chronic backache of approximately $28 billion in the United States. CONCLUSION: The labor productivity losses from chronic backache differed by gender and other sociodemographic characteristics. The aggregate labor productivity losses associated with chronic backache were quite large and comparable to estimates of the direct medical costs associated with treating this chronic illness. AD - Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520, USA. John.Rizzo@Yale.edu AN - 9794341 AU - Rizzo, J. A. AU - Abbott, T. A., 3rd AU - Berger, M. L. DA - Oct DO - 10.1097/00005650-199810000-00006 DP - NLM ET - 1998/10/30 IS - 10 KW - *Absenteeism Adolescent Adult Aged Back Pain/*economics/epidemiology Cross-Sectional Studies *Efficiency Female Health Expenditures/statistics & numerical data Humans Incidence Male Middle Aged Multivariate Analysis Occupational Diseases/*economics/epidemiology Sick Leave/*economics United States/epidemiology LA - eng N1 - Rizzo, J A Abbott, T A 3rd Berger, M L Journal Article United States Med Care. 1998 Oct;36(10):1471-88. doi: 10.1097/00005650-199810000-00006. PY - 1998 SN - 0025-7079 (Print) 0025-7079 SP - 1471-88 ST - The labor productivity effects of chronic backache in the United States T2 - Med Care TI - The labor productivity effects of chronic backache in the United States VL - 36 ID - 3769 ER - TY - JOUR AB - Purpose: Myringotomy and tube placement is one of the most frequently performed ear, nose and throat (ENT) surgeries in the pediatric population. Effective anesthetic management is vital to ensuring successful ambulatory care and ensuring child and parental satisfaction. Recent findings: This review summarizes recently published studies about the long-term effects of general anesthesia in young children, novel approaches to preoperative fasting and simplified approaches to the assessment and management of emergence delirium (ED) and emergence agitation (EA). New developments in perioperative ambulatory care, including management of comorbidities and day care unit logistics, are discussed. Summary: Long-term follow-up of children exposed to general anesthesia before the age of 4 years has limited impact on academic achievement or cognitive performance and should not delay the treatment of common ENT pathology, which can impair speech and language development. A more liberal approach to fasting, employing a 6-4-0 regime allowing children fluids up until theater, may become an accepted practice in future. ED and EA should be discriminated from pain in recovery and, where the child is at risk of harm, should be treated promptly. Postoperative pain at home remains problematic in ambulatory surgery and better parental education is needed. Effective ambulatory care ultimately requires a well-coordinated team approach from effective preassessment to postoperative follow-up. AN - WOS:000399584400001 AU - Robinson, H. AU - Engelhardt, T. DO - 10.2147/lra.S113591 N1 - Robinson, Hal Engelhardt, Thomas PY - 2017 SN - 1178-7112 SP - 41-49 ST - Ambulatory anesthetic care in children undergoing myringotomy and tube placement: current perspectives T2 - Local and Regional Anesthesia TI - Ambulatory anesthetic care in children undergoing myringotomy and tube placement: current perspectives UR - ://WOS:000399584400001 VL - 10 ID - 2121 ER - TY - JOUR AB - OBJECTIVE: Fibromyalgia (FM) is characterized by widespread pain that can lead to significant patient disability, complex management decisions for physicians, and economic burden on society. We investigated the total costs of FM in an employer population. METHODS: Administrative claims data of a Fortune 100 manufacturer were used to quantify direct (i.e., medical and pharmaceutical claims) and indirect (i.e., disability claims and imputed absenteeism) costs associated with FM. A total of 4699 patients with at least one FM claim between 1996 and 1998 were contrasted with a 10% random sample of the overall beneficiary population. Employee-only subsets of both samples also were drawn. RESULTS: Medical utilization, receipt of prescription drugs, and annual total costs were proportionately similar yet significantly greater among FM claimants than the overall sample (all p < 0.0001). Total annual costs for FM claimants were $5945 versus $2486 for the typical beneficiary (p < 0.0001). Six percent of these costs were attributable to FM-specific claims. The prevalence of disability was twice as high among FM employees than overall employees (p < 0.0001). For every dollar spent on FM-specific claims, the employer spent another $57 to $143 on additional direct and indirect costs. CONCLUSION: Hidden costs of disability and comorbidities greatly increase the true burden of FM. Regardless of the clinical understanding of FM, when a claim for FM is present, considerable costs are involved. Findings suggest that within the management of FM there may be large cost-offset opportunities for reductions in patient, physician, and employer burdens. AD - Eli Lilly and Company, Indianapolis, Indiana 46285, USA. rlrobinson@lilly.com AN - 12784409 AU - Robinson, R. L. AU - Birnbaum, H. G. AU - Morley, M. A. AU - Sisitsky, T. AU - Greenberg, P. E. AU - Claxton, A. J. DA - Jun DP - NLM ET - 2003/06/05 IS - 6 KW - Absenteeism Adolescent Adult Comorbidity Cost of Illness Drug Prescriptions/economics Employer Health Costs/*statistics & numerical data Employment/economics Female Fibromyalgia/*economics/*epidemiology Health Expenditures Health Services/statistics & numerical data Humans Male Middle Aged Occupational Health *Workers' Compensation LA - eng N1 - Robinson, Rebecca L Birnbaum, Howard G Morley, Melissa A Sisitsky, Tamar Greenberg, Paul E Claxton, Ami J Journal Article Research Support, Non-U.S. Gov't Canada J Rheumatol. 2003 Jun;30(6):1318-25. PY - 2003 SN - 0315-162X (Print) 0315-162x SP - 1318-25 ST - Economic cost and epidemiological characteristics of patients with fibromyalgia claims T2 - J Rheumatol TI - Economic cost and epidemiological characteristics of patients with fibromyalgia claims VL - 30 ID - 3400 ER - TY - JOUR AB - AIM: Renal pathologies have an hard impact on ill children's life style, psychic and physical development. In the last years, even if medical cures allowed these children to live longer and to have a better quality of life, today both their families and themselves have to face a lot of difficulties due to the kind of pathology. These children show behaviour troubles, bad sociability, aggressiveness, poor school performance, anxiety and depression, and then the subjects with chronic renal failure show a retard in neurological and cognitive development. In this study we evaluated the impact that the chronic renal illness has on children and adolescents' quality life. METHODS: For this study, we have used the Impact of Childhood Illness Scale. It includes 30 questions that value 4 aspects of the child and family's life style: illness and its treatment, impact on the child, impact on parents and impact on the family. For every question, it considers the frequency of the problem and the degree of the worry that it causes. We gave the questionnaire to 47 couples of parents' children who are suffering from chronic renal diseases (19 subjects with nephrotic syndrome, 7 with chronic glomerulenephritis, 10 with chronic renal failure, 5 dialysed, 6 with kidney transplant). All parents compiled the questionnaire. RESULTS: The obtained results showed that developing age subjects, who are affected by chronic renal diseases, can have emotional and behavioural difficulties that have an effect on subject and on his family. Their parents live in a continuous stress state because chronic pain and anxiety cause depression, a sense of inadequacy and frustration. CONCLUSIONS: As in every chronic physical illness, the sick child and his family are obliged to face a series of physical, behavioural and emotional changes. Besides, they are faced by possible collateral effects of the illness and of its treatments on development. AD - Dipartimento di Psicologia, Università degli Studi di Palermo, Palermo, Italy. mroccella@tin AN - 16170296 AU - Roccella, M. AU - Leggio, L. AU - Parisi, L. AU - Turdo, G. AU - Testa, D. DA - Jun DP - NLM ET - 2005/09/20 IS - 3 KW - Achievement Adolescent Anxiety/epidemiology/etiology Child Child Behavior Disorders/epidemiology Child, Preschool Female Humans Kidney Failure, Chronic/epidemiology/*psychology Male Quality of Life/*psychology Surveys and Questionnaires LA - ita N1 - Roccella, M Leggio, L Parisi, L Turdo, G Testa, D English Abstract Journal Article Italy Minerva Pediatr. 2005 Jun;57(3):119-28. OP - La qualitá della vita in soggetti in etá evolutiva affetti da patologie renali croniche. PY - 2005 SN - 0026-4946 (Print) 0026-4946 SP - 119-28 ST - [The quality of life in developing age subjects with chronic renal diseases] T2 - Minerva Pediatr TI - [The quality of life in developing age subjects with chronic renal diseases] VL - 57 ID - 3837 ER - TY - JOUR AB - PURPOSE: Deficiencies in pain knowledge and attitudes among students and health practitioners are well documented. Occupational therapists (OTs) commonly care for patients who present with pain, and their knowledge of the field presumably impacts that care. This study presents the results of testing OT students' pain knowledge in order to assess the effects of embedding pain teaching in a generic master's-level OT course and to determine specific topics that should be addressed to improve upon existing OT curricula. METHOD: During the academic years 2004 through 2009, 194 OT students were administered a test of pain knowledge and attitudes on the first and last day of a required class which focused on procedural reasoning. RESULTS: The results indicated significant (p < 0.001) improvement in test scores after participation in the class. Whereas only 35% of students met the minimum "adequate" standard for pain knowledge at pre-test, 92% of students met this standard at post-test. CONCLUSIONS: The results demonstrate the effectiveness of a course taught by an instructor with pain expertise. In addition, analysis of individual items highlights the need for curricula to address theoretical versus practical understanding of pain, the ever-evolving science of pain, and pervasive biases about specific pain topics. IMPLICATIONS FOR REHABILITATION: Deficiencies in pain knowledge and attitudes among students and health practitioners are well documented. Occupational therapists (OTs) commonly care for patients who present with pain, and their knowledge of the field presumably impacts that care. The results of this study demonstrate the effectiveness of an OT course taught by an instructor with pain expertise. OT curricula should address pain in special populations (e.g. children and the elderly), acute versus chronic pain, theoretical versus practical understanding of pain, the ever-evolving science of pain, and pervasive biases about specific pain topics (e.g. malingering and opioid addiction). AD - Department of Occupational Therapy, Spaulding Rehabilitation Hospital , Medford, MA , USA . AN - 23390881 AU - Rochman, D. L. AU - Sheehan, M. J. AU - Kulich, R. J. DO - 10.3109/09638288.2013.766273 DP - NLM ET - 2013/02/09 IS - 22 KW - Analysis of Variance Clinical Competence *Curriculum Health Knowledge, Attitudes, Practice Humans Massachusetts Occupational Therapy/*education Pain Pain Management Pain Measurement Program Evaluation LA - eng N1 - 1464-5165 Rochman, Deborah L Sheehan, Michael J Kulich, Ronald J Evaluation Study Journal Article England Disabil Rehabil. 2013;35(22):1933-40. doi: 10.3109/09638288.2013.766273. Epub 2013 Feb 8. PY - 2013 SN - 0963-8288 SP - 1933-40 ST - Evaluation of a pain curriculum for occupational therapists: experiences from a master's-level graduate program over six years T2 - Disabil Rehabil TI - Evaluation of a pain curriculum for occupational therapists: experiences from a master's-level graduate program over six years VL - 35 ID - 3835 ER - TY - JOUR AB - OBJECTIVE: To investigate whether backpack weight is associated with back pain and back pathology in school children. DESIGN: Cross-sectional study. SETTING: Schools in Northern Galicia, Spain. PATIENTS: All children aged 12-17. INTERVENTIONS: Backpack weight along with body mass index, age and gender. MAIN OUTCOME MEASURES: Back pain and back pathology. RESULTS: 1403 school children were analysed. Of these, 61.4% had backpacks exceeding 10% of their body weight. Those carrying the heaviest backpacks had a 50% higher risk of back pain (OR 1.50 CI 95% 1.06 to 2.12) and a 42% higher risk of back pathology, although this last result was not statistically significant (OR 1.42 CI 95% 0.86 to 2.32). Girls presented a higher risk of back pain compared with boys. CONCLUSIONS: Carrying backpacks increases the risk of back pain and possibly the risk of back pathology. The prevalence of school children carrying heavy backpacks is extremely high. Preventive and educational activities should be implemented in this age group. AU - Rodríguez-Oviedo, Paloma AU - Ruano-Ravina, Alberto AU - Pérez-Ríos, Mónica AU - García, Francisco Blanco AU - Gómez-Fernández, Dorotea AU - Fernández-Alonso, Anselmo AU - Carreira-Núñez, Isabel AU - García-Pacios, Pilar AU - Turiso, Javier DA - 2012/08// DO - 10.1136/archdischild-2011-301253 DP - PubMed IS - 8 J2 - Arch Dis Child KW - Adolescent Back Pain Body Mass Index Child Cross-Sectional Studies Female Humans Lifting Male Risk Factors Schools Scoliosis Sex Distribution Spain Students Surveys and Questionnaires Weight-Bearing LA - eng PY - 2012 SN - 1468-2044 SP - 730-732 ST - School children's backpacks, back pain and back pathologies T2 - Archives of Disease in Childhood TI - School children's backpacks, back pain and back pathologies UR - http://www.ncbi.nlm.nih.gov/pubmed/22408188 VL - 97 ID - 96 ER - TY - JOUR AB - Introduction. Chronic pain in children and adolescents has a major impact on their life in terms of school, sleep as well as family and social life. Teenagers aged 13-15 and girls are at the highest risk. Zeltzer et al. established a bio-psychosocial model of chronic pain in 1998 to account for all its dimensions and advocated a multidisciplinary management plan. Programs based on their principles target specific symptoms such as anxiety and loss of function, while treating underlying factors and teaching coping skills to patients and their families. They aim for patients to regain autonomy rather than focusing on pain resolution. Such programs, with varied protocols, have existed outside of France for approximately 15 years. The efficacy of these multidisciplinary programs has been shown in studies in Germany, the United Kingdom, the United States, Canada, and Australia. To our knowledge, there are no French studies on this topic; therefore, our aim was to describe a French program. We hypothesized that the program would be effective in reducing chronic pain and its impact. Methods. The aim of this study was to describe the multidisciplinary management of chronic pain in a French pediatric functional rehabilitation center. It is a public health establishment located in the suburbs of Lille, offering care for children aged 0-18 with various conditions. It has 52 hospital beds, can accommodate up to 22 day-hospital visits per day and has comprehensive technical facilities. This prospective study consisted in a chart review of all consecutive patients who were hospitalized in the functional rehabilitation center for chronic pain with significant disability since 2010. We reviewed the treatment protocol for each patient as well as the treatment results for the composite primary endpoint, comprising pain characteristics and the impact of pain on function and schooling after discharge. Results. Twenty-nine patients, aged 9.4-17.8 years, 62.1% of whom were girls, were hospitalized for chronic pain with a significant impact on their daily life between 2010 and August 2014. The most common diagnosis was complex regional pain syndrome type 1 (CRPS1) (37.9%). Pain had major consequences, with total disability in 69% of cases and 100% of children taking pain medications. In 65.5% of cases, patients were hospitalized in an inpatient setting, and 34.5% attended an outpatient program. Treatment lasted from 1 to 68 weeks (mean, 24.3; standard deviation [SD], 21.6). Patients received a combination of medical care, physical therapy (100%), occupational therapy (37.9%), psychological counseling (100%), pain medications (96.6%), and schooling (96.6%). Pain improved significantly in 89.7% of patients (95% confidence interval [95% CI] [0.73-0.98]) and pain medication consumption decreased significantly in 72.4% of children (95% CI [0.53-0.87]). Patients who had stopped walking could ambulate again in 91.7% of cases (95% CI [0.73-0.99]) and 86.4% of patients who had been missing school were back at school full time (95% CI [0.65-0.97]). There were no significant differences for these results between inpatient and out-patient management programs. Improvements were maintained at 3-6 months after discharge in 83.3% of cases. Conclusion. The multidisciplinary pain management program in this French pediatric functional rehabilitation center shows results comparable to the programs described in other countries. Chronic pain should be evaluated with standardized and validated tools, such as the measurement of the pain-related disability with the Functional Disability Index. (C) 2016 Elsevier Masson SAS. All rights reserved. AN - WOS:000382899000006 AU - Roessler, N. AU - Debeaurepaire, C. A. AU - Deprez, A. AU - Tanche, L. AU - Pavageau, V. AU - Hamain, A. AU - Grave, C. AU - Yatzimirsky, A. AU - Vallee, L. AU - Avez-Couturier, J. DA - Aug DO - 10.1016/j.arcped.2016.05.016 IS - 8 N1 - Roessler, N. Debeaurepaire, C. Allen Deprez, A. Tanche, L. Pavageau, V. Hamain, A. Grave, C. Yatzimirsky, A. Vallee, L. Avez-Couturier, J. 1769-664x PY - 2016 SN - 0929-693X SP - 806-814 ST - Multidisciplinary management of children with disabling chronic pain in a French pediatric rehabilitation center: Current management and perspectives T2 - Archives De Pediatrie TI - Multidisciplinary management of children with disabling chronic pain in a French pediatric rehabilitation center: Current management and perspectives UR - ://WOS:000382899000006 VL - 23 ID - 2153 ER - TY - JOUR AB - Objective: To evaluate the effect of a social cognitive theory (SCT)-based intervention on the constructs of situational perception, behavioral capabilities, outcome expectations, outcome expectancies, and self-efficacy concerning over-the-counter (OTC) pain medications among an adolescent population. Design: Pre-posttest control group design. Setting: Rural high school in the southeastern United States, between February and March 2011. Participants: 203 high school students recruited from 10 classrooms. Intervention: Classrooms were randomly assigned to an SCT-based education intervention group or the control group. Pre- and posttest data were collected from each group 2 weeks before and 2 weeks after the intervention was delivered. Main outcome measures: Change in the five selected constructs of SCT. Results: Compared with the control group, significant improvements at posttest were observed in the intervention group for outcome expectations of OTC pain medications (P <= 0.05) and behavioral capabilities (P <= 0.05). Conclusion: The results suggest that lessons based on SCT to improve the outcome expectations that an adolescent population places on the consumption of OTC pain medications may assist in developing the knowledge and skills needed to consume these products properly. AN - WOS:000315937700009 AU - Rogers, E. R. AU - King, S. R. DA - Jan-Feb DO - 10.1331/JAPhA.2013.11231 IS - 1 N1 - Rogers, Erica R. King, Sean R. PY - 2013 SN - 1544-3191 SP - 30-38 ST - Intervention based on social cognitive theory: Evaluating adolescents' knowledge of OTC pain medications T2 - Journal of the American Pharmacists Association TI - Intervention based on social cognitive theory: Evaluating adolescents' knowledge of OTC pain medications UR - ://WOS:000315937700009 VL - 53 ID - 2396 ER - TY - JOUR AB - Objectives: More adolescents report pain now than previously. In Norway, episodic pain problems have been reported by 60% of children and adolescents aged 8-18 years, with 21% reporting duration of pain of more than 3 months. Since adolescents spend much time at school, the attitude and behaviour of teachers play important roles regarding the experience of pain felt by adolescents in everyday life. Yet research on how teachers perceive the pain experienced by adolescents in a school setting is limited. We therefore seek to gain insight to teachers' classroom experiences with (1) adolescent's self-reported pain symptoms; (2) adolescents management of their pain and (3) how to help adolescents manage their pain. Setting: Teachers in 5 junior high schools in Norway representing municipalities in 3 rural areas and 2 cities. Research design: A qualitative study with an explorative design comprising 5 focus group interviews. Each group consisted of 3-8 junior high school teachers. A semistructured interview guide was used to cover the issues. The transcribed text was analysed with qualitative content analysis. Participants: 22 teachers participated (5 men, 17 women; age range 29-62 years) with teaching experience ranging from 3 to nearly 40 years. Results: The main theme describing the experience of teachers with adolescents' pain in everyday life is that pain and management of pain is a social, physical and psychological interwoven phenomenon. Through empirical analyses, 3 subcategories emerged: (1) everyday pain-expressing strenuous life; (2) managing pain-escaping struggle and (3) strategies of teachers-support and normalisation. Conclusions: Teachers have a biopsychosocial understanding and approach to pain experienced by adolescents. This understanding influences the role of teachers as significant others in the lives of adolescents with regard to pain and management of their pain in a school setting. AN - WOS:000360863100034 AU - Rohde, G. AU - Westergren, T. AU - Haraldstad, K. AU - Johannessen, B. AU - Hoie, M. AU - Helseth, S. AU - Fegran, L. AU - Slettebo, A. C7 - e007989 DO - 10.1136/bmjopen-2015-007989 IS - 9 N1 - Rohde, Gudrun Westergren, Thomas Haraldstad, Kristin Johannessen, Berit Hoie, Magnhild Helseth, Solvi Fegran, Liv Slettebo, Ashild fegran, liv/AAW-2160-2020 Westergren, Thomas/0000-0003-4253-1996; Fegran, Liv/0000-0001-5470-8686 PY - 2015 SN - 2044-6055 ST - Teachers' experiences of adolescents' pain in everyday life: a qualitative study T2 - Bmj Open TI - Teachers' experiences of adolescents' pain in everyday life: a qualitative study UR - ://WOS:000360863100034 VL - 5 ID - 2256 ER - TY - JOUR AB - Chronic pain in childhood is common and if untreated may lead to significant pain-related disability, emotional disturbance and poor school attendance. These children and adolescents are often successfully managed outside of specialist paediatric pain management clinics in a wide range of clinical settings. However, some children require the expertise of a multidisciplinary pain management team in a dedicated paediatric centre. Following multidisciplinary assessment an individualized pain management plan is agreed with the family. Treatment options can be classified into pharmacological, physical and psychological therapies. The aim of treatment is to facilitate a restoration of function for the child, working with the family as a whole. AN - WOS:000390864400001 AU - Rolfe, P. M. DA - Nov DO - 10.1016/j.mpaic.2016.08.009 IS - 11 N1 - Rolfe, Paul M. 1878-7584 PY - 2016 SN - 1472-0299 SP - 531-535 ST - Paediatric chronic pain T2 - Anaesthesia and Intensive Care Medicine TI - Paediatric chronic pain UR - ://WOS:000390864400001 VL - 17 ID - 2134 ER - TY - JOUR AB - Chronic pain in childhood is common and if untreated may lead to significant pain-related disability, emotional disturbance and poor school attendance. Many children and adolescents are successfully managed outside of specialist paediatric pain management clinics in a wide range of clinical settings. However, some children require the expertise of a multidisciplinary pain management team in a dedicated paediatric centre. Following multidisciplinary assessment an individualized pain management plan is agreed with the family. Treatment options can be classified into pharmacological, physical and psychological therapies. The aim of treatment is to facilitate a restoration of function for the child, working with the family as a whole. AN - WOS:000489330700001 AU - Rolfe, P. M. DA - Oct DO - 10.1016/j.mpaic.2019.07.010 IS - 10 N1 - Rolfe, Paul M. 1878-7584 PY - 2019 SN - 1472-0299 SP - 539-542 ST - Paediatric chronic pain T2 - Anaesthesia and Intensive Care Medicine TI - Paediatric chronic pain UR - ://WOS:000489330700001 VL - 20 ID - 1880 ER - TY - JOUR AB - Fifteen children (16 years and younger, 10 females, 5 males, mean age 13 years) with juvenile primary fibromyalgia syndrome (JPFS) were seen in a private rheumatology practice over two years. This represented 45 percent of the total number of pediatric rheumatology patients. Symptoms included polymyalgias, polyarthralgias, nonrestorative sleep, difficulty concentrating in school and fatigue. Examination revealed typical tender points, absence of joint swelling, synovitis or nodules and absence of neurological findings. Dolorimetry was abnormal and standard laboratory tests were normal. Most of these patients (67 percent) had seen three or more doctors prior to their rheumatological evaluation and not (60 percent) were told they had juvenile chronic arthritis. Other diagnoses offered were "growing pains" (20 percent), hysteria (7 percent) and psychological problems (7 percent). None of the JPFS patients responded to salicylate or other anti-inflammatory medication. Most (73 percent) responded to cyclobenzaprine, mean dose 12.75 mg. (range 5-25 mg. qhs). JPFS is a very common pediatric rheumatologic problem and is confused with other disorders. Reassurance is very important in the therapy since many parents are fearful that their children may have a potentially crippling disorder. Medication, especially with tricyclics, moderate exercise and proper sleep are also mainstays of therapy. AN - 2031345 AU - Romano, T. J. DA - Mar DP - NLM ET - 1991/03/01 IS - 3 KW - Adolescent Amitriptyline/administration & dosage/analogs & derivatives Antidepressive Agents/administration & dosage Child Diagnosis, Differential Drug Therapy, Combination Female Fibromyalgia/*diagnosis/drug therapy Humans Male *Muscle Relaxants, Central LA - eng N1 - Romano, T J Journal Article United States W V Med J. 1991 Mar;87(3):112-4. PY - 1991 SN - 0043-3284 (Print) 0043-3284 SP - 112-4 ST - Fibromyalgia in children; diagnosis and treatment T2 - W V Med J TI - Fibromyalgia in children; diagnosis and treatment VL - 87 ID - 3258 ER - TY - JOUR AB - OBJECTIVE: The relationship between abuse and violence and the care of neurological patients is an important topic not often addressed, and studies suggest that most neurologists do not routinely screen patients for abuse. In this pilot study, our aim was to demonstrate a simple and effective strategy for screening patients for exposure to abuse. METHODS: A total of 103 consecutive patients reporting to an academic neurology clinic specializing in autonomic and movement disorders were screened for a history of abuse and violence. A set of 6 questions were included in the standard patient intake questionnaire. The questions were then repeated verbally during the physician history taking. All patients were provided with information on available local resources for abuse counseling during the visit. Retrospective chart review analysis was performed to determine the prevalence of history of abuse in the population, the most common type of abuse suffered, and the number of individuals reporting current abuse. RESULTS: Twenty-two of the 103 patients (21%) screened for abuse reported exposure to abuse or violence. Two patients with ongoing issues with abuse were identified. The most commonly reported abuse was being a witness to violence (65%), followed by physical abuse (41%), sexual and emotional abuse (36% each), and financial abuse (23%). The neurological disorders most frequently observed in these patients were chronic pain, neuropathy, autonomic dysfunction, headache, and Parkinson disease. CONCLUSIONS: Patients with neurological disorders may have been exposed to abuse and violence. It is important to recognize these issues and address them routinely in the neurological evaluation. A simple, effective way to accomplish screening in the outpatient setting is through the use of an intake questionnaire combined with verbal clarification. AD - Department of Neurology, Boston University School of Medicine, Boston, MA 02118, USA. AN - 23269099 AU - Roque, A. M. AU - Weinberg, J. AU - Hohler, A. D. DA - Jan DO - 10.1097/NRL.0b013e31827c6c26 DP - NLM ET - 2012/12/28 IS - 1 KW - Autonomic Nervous System Diseases/epidemiology/*psychology Child Child Abuse/psychology Female Humans Male Mass Screening Middle Aged Movement Disorders/epidemiology/*psychology Pilot Projects Retrospective Studies Sex Offenses/psychology Spouse Abuse/psychology Surveys and Questionnaires Violence/*psychology/statistics & numerical data LA - eng N1 - 2331-2637 Roque, Ashley M Weinberg, Janice Hohler, Anna Depold Journal Article United States Neurologist. 2013 Jan;19(1):7-10. doi: 10.1097/NRL.0b013e31827c6c26. PY - 2013 SN - 1074-7931 SP - 7-10 ST - Evaluating exposure to abuse and violence in neurological patients T2 - Neurologist TI - Evaluating exposure to abuse and violence in neurological patients VL - 19 ID - 4138 ER - TY - JOUR AB - PURPOSE: To identify baseline characteristics of adults with chronic low back pain (cLBP) that predict response (i.e., a clinically important improvement) and/or modify treatment effect across three nonpharmacologic interventions. DESIGN: Secondary analysis of a randomized controlled trial. SETTING: Academic safety net hospital and seven federally qualified community health centers. SUBJECTS: Adults with cLBP (N = 299). METHODS: We report patient characteristics that were predictors of response and/or modified treatment effect across three 12-week treatments: yoga, physical therapy [PT], and a self-care book. Using preselected characteristics, we used logistic regression to identify predictors of "response," defined as a ≥30% improvement in the Roland Morris Disability Questionnaire. Then, using "response" as our outcome, we identified baseline characteristics that were treatment effect modifiers by testing for statistical interaction (P < 0.05) across two comparisons: 1) yoga-or-PT vs self-care and 2) yoga vs PT. RESULTS: Overall, 39% (116/299) of participants were responders, with more responders in the yoga-or-PT group (42%) than the self-care (23%) group. There was no difference in proportion responding to yoga (48%) vs PT (37%, odds ratio [OR] = 1.5, 95% confidence interval = 0.88 - 2.6). Predictors of response included having more than a high school education, a higher income, employment, few depressive symptoms, lower perceived stress, few work-related fear avoidance beliefs, high pain self-efficacy, and being a nonsmoker. Effect modifiers included use of pain medication and fear avoidance beliefs related to physical activity (both P = 0.02 for interaction). When comparing yoga or PT with self-care, a greater proportion were responders among those using pain meds (OR = 5.3), which differed from those not taking pain meds (OR = 0.94) at baseline. We also found greater treatment response among those with lower (OR = 7.0), but not high (OR = 1.3), fear avoidance beliefs around physical activity. CONCLUSIONS: Our findings revealed important subgroups for whom referral to yoga or PT may improve cLBP outcomes. AD - Department of Family Medicine, Boston University School of Medicine and Boston Medical Center, Boston, Massachusetts, USA. Department of Rehabilitation Science, Massachusetts General Hospital Institute of Health Professions, Boston, Massachusetts, USA. Slone Epidemiology Center, Boston University School of Medicine, Boston, Massachusetts, USA. Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, Massachusetts, USA. School of Health and Rehabilitation Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. Kaiser Permanente Washington Health Research Institute, Seattle, Washington, USA. Department of Epidemiology, University of Washington, Seattle, Washington, USA. AN - 32662833 AU - Roseen, E. J. AU - Gerlovin, H. AU - Felson, D. T. AU - Delitto, A. AU - Sherman, K. J. AU - Saper, R. B. C2 - PMC7861465 DA - Feb 4 DO - 10.1093/pm/pnaa153 DP - NLM ET - 2020/07/15 IS - 1 KW - Adult Books Humans *Low Back Pain/therapy Physical Therapy Modalities Self Care Treatment Outcome *Yoga *Chronic Low Back Pain *Effect Modification *Health Disparities *Physical Therapy *Predictor of Response *Primary Care LA - eng N1 - 1526-4637 Roseen, Eric J Gerlovin, Hanna Felson, David T Delitto, Anthony Sherman, Karen J Saper, Robert B F32 AT009272/AT/NCCIH NIH HHS/United States K23 AT010487/AT/NCCIH NIH HHS/United States R01 AT005956/AT/NCCIH NIH HHS/United States UL1 TR001430/TR/NCATS NIH HHS/United States Journal Article Randomized Controlled Trial Research Support, N.I.H., Extramural Pain Med. 2021 Feb 4;22(1):165-180. doi: 10.1093/pm/pnaa153. PY - 2021 SN - 1526-2375 (Print) 1526-2375 SP - 165-180 ST - Which Chronic Low Back Pain Patients Respond Favorably to Yoga, Physical Therapy, and a Self-care Book? Responder Analyses from a Randomized Controlled Trial T2 - Pain Med TI - Which Chronic Low Back Pain Patients Respond Favorably to Yoga, Physical Therapy, and a Self-care Book? Responder Analyses from a Randomized Controlled Trial VL - 22 ID - 4167 ER - TY - JOUR AB - OBJECTIVES: To describe the characteristics and attitudes toward complementary and alternative medicine (CAM) use among primary care patients with chronic pain disorders and to determine if CAM use is associated with better pain control. DESIGN: Cross-sectional survey. SUBJECTS: Four hundred sixty-three patients suffering from chronic, nonmalignant pain receiving primary care at 12 U.S. academic medical centers. OUTCOME MEASURE: Self-reported current CAM usage by patients with chronic pain disorders. RESULTS: The survey had an 81% response rate. Fifty-two percent reported current use of CAM for relief of chronic pain. Of the patients that used CAM, 54% agreed that nontraditional remedies helped their pain and 14% indicated that their individual alternative remedy entirely relieved their pain. Vitamin and mineral supplements were the most frequently used CAM modalities. There was no association between reported use of CAM and pain severity, functional status, or perceived self-efficacy. Patients who reported having at least a high school education (odds ratio [OR] 1.1, 95% confidence interval [CI] 1.02-1.19, P = 0.016) and high levels of satisfaction with their health care (OR 1.47, 95% CI 1.13-1.91, P = 0.004) were significantly more likely to report using CAM. CONCLUSIONS: Complementary and alternative therapies were popular among patients with chronic pain disorders surveyed in academic primary care settings. When asked to choose between traditional therapies or CAM, most patients still preferred traditional therapies for pain relief. We found no association between reported CAM usage and pain severity, functional status, or self-efficacy. AD - Division of Internal Medicine, Department of Medicine, University of Florida, Gainesville, Florida 32610-0277, USA. rosenei@medicine.ufl.edu AN - 18564996 AU - Rosenberg, E. I. AU - Genao, I. AU - Chen, I. AU - Mechaber, A. J. AU - Wood, J. A. AU - Faselis, C. J. AU - Kurz, J. AU - Menon, M. AU - O'Rorke, J. AU - Panda, M. AU - Pasanen, M. AU - Staton, L. AU - Calleson, D. AU - Cykert, S. DA - Nov DO - 10.1111/j.1526-4637.2008.00477.x DP - NLM ET - 2008/06/21 IS - 8 KW - Adult Aged Complementary Therapies/*statistics & numerical data Cross-Sectional Studies Female *Health Knowledge, Attitudes, Practice Humans Middle Aged *Pain Management Pain Measurement Physician-Patient Relations *Primary Health Care Self Medication/statistics & numerical data Surveys and Questionnaires United States LA - eng N1 - 1526-4637 Rosenberg, Eric I Genao, Inginia Chen, Ian Mechaber, Alex J Wood, Jo Ann Faselis, Charles J Kurz, James Menon, Madhu O'Rorke, Jane Panda, Mukta Pasanen, Mark Staton, Lisa Calleson, Diane Cykert, Sam 1-D14-HP00169-01/PHS HHS/United States D14-HP-00182/PHS HHS/United States Journal Article Multicenter Study Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. England Pain Med. 2008 Nov;9(8):1065-72. doi: 10.1111/j.1526-4637.2008.00477.x. Epub 2008 Jun 18. PY - 2008 SN - 1526-2375 SP - 1065-72 ST - Complementary and alternative medicine use by primary care patients with chronic pain T2 - Pain Med TI - Complementary and alternative medicine use by primary care patients with chronic pain VL - 9 ID - 3770 ER - TY - JOUR AB - BACKGROUND AND OBJECTIVES: Pediatric procedural pain management (PPPM) is best practice but was inconsistent in our large multisite general academic medical center. We hypothesized that quality improvement (QI) methods would improve and standardize PPPM in our health system within inpatient pediatric units. We aimed to increase topical anesthetic use from 10% to 40%, improve nursing pediatric pain knowledge, and increase parent satisfaction around procedures for children admitted to a general tertiary academic medical center. METHODS: We used QI methods including needs assessment, self-identified champions, small tests of change, leadership accountability, data transparency, and a train-the-peer-trainer approach to implement PPPM. We measured inpatient use of topical anesthetic (goal of 40% of admissions), nursing pain knowledge, and parent satisfaction with child comfort during procedures. We used statistical process control and basic statistics to analyze data in this interrupted time series design. RESULTS: Over 18 months, use of topical lidocaine rose from 10% to 36.5% for all inpatient admissions, resulting in a centerline shift. Nursing pain knowledge scores increased 7%. Mean parent satisfaction around procedural comfort increased from 83% to 88%. CONCLUSIONS: A child-focused QI initiative around PPPM can succeed in a multisite general academic medical center. Key success factors for this effort included accountability, multidisciplinary core leadership, housewide training in a novel educational evidence-based framework, and use of data and champions to promote nurse and physician engagement. Future work will focus on sustaining and monitoring change. AD - Department of Pediatrics, New York University School of Medicine, New York, New York; NYU Langone Medical Center, New York, New York; rebecca.rosenberg@nyumc.org. Department of Pharmacy, Westchester Medical Center, Valhalla, New York; St. Luke's Medical Center, New York, New York; and. NYU Langone Medical Center, New York, New York; NYU Langone Medical Center, New York, New York; New York University School of Nursing, New York, New York. AN - 27173738 AU - Rosenberg, R. E. AU - Klejmont, L. AU - Gallen, M. AU - Fuller, J. AU - Dugan, C. AU - Budin, W. AU - Olsen-Gallagher, I. DA - Jun DO - 10.1542/hpeds.2015-0240 DP - NLM ET - 2016/05/14 IS - 6 KW - Administration, Cutaneous Anesthetics, Local/*administration & dosage Child Health Care Surveys Health Knowledge, Attitudes, Practice Hospitals, University Humans *Inpatients Interrupted Time Series Analysis Lidocaine/*administration & dosage Needs Assessment *Nurse's Role Pain/etiology/*nursing/prevention & control Pain Management/nursing Parents *Patient Satisfaction *Pediatrics *Quality Improvement Surveys and Questionnaires LA - eng N1 - Rosenberg, Rebecca E Klejmont, Liana Gallen, Meghan Fuller, Jackie Dugan, Christina Budin, Wendy Olsen-Gallagher, Ingrid Journal Article Research Support, Non-U.S. Gov't United States Hosp Pediatr. 2016 Jun;6(6):359-68. doi: 10.1542/hpeds.2015-0240. Epub 2016 May 12. PY - 2016 SN - 2154-1663 (Print) 2154-1671 SP - 359-68 ST - Making Comfort Count: Using Quality Improvement to Promote Pediatric Procedural Pain Management T2 - Hosp Pediatr TI - Making Comfort Count: Using Quality Improvement to Promote Pediatric Procedural Pain Management VL - 6 ID - 3700 ER - TY - JOUR AN - WOS:000408250700003 AU - Rosenbloom, B. N. AU - Rabbitts, J. A. AU - Palermo, T. M. DA - Sep DO - 10.1097/j.pain.0000000000000888 IS - 9 N1 - Rosenbloom, Brittany N. Rabbitts, Jennifer A. Palermo, Tonya M. Rabbitts, Jennifer/0000-0003-4800-1080 1872-6623 PY - 2017 SN - 0304-3959 SP - 1629-1632 ST - A developmental perspective on the impact of chronic pain in late adolescence and early adulthood: implications for assessment and intervention T2 - Pain TI - A developmental perspective on the impact of chronic pain in late adolescence and early adulthood: implications for assessment and intervention UR - ://WOS:000408250700003 VL - 158 ID - 2079 ER - TY - JOUR AB - Background. There is a need for increased palliative care training during pediatric residency. Objective. In this pilot study, we created a comprehensive experiential model to teach palliative care skills to pediatric residents. Our Comfort Care Modules (CCMs) address pediatric palliative care (PPC) topics of breaking bad news, dyspnea, anxiety, pain management, and the dying child. We also evaluated a scoring system and gathered qualitative data. Methods. The CCMs are part of the University of California San Diego pediatric residency's second-year curriculum. Comparisons were made for statistical trends between residents exposed to the modules (n = 15) and those not exposed (n = 4). Results. Nineteen of 36 residents (52%) completed surveys to self-rate their preparedness, knowledge, and confidence about PPC before and after the intervention. Resident scores increased in all areas. All improvements reached statistical significance except confidence when breaking bad news. Overall, the resident feedback about the CCMs was positive. Conclusions. This study demonstrates that the CCMs can be performed effectively in an academic setting and can benefit residents' self-perception of preparedness, confidence, and knowledge about pediatric palliative care. In the future, we plan to implement the modules on a larger scale. We encourage their use in interprofessional settings and across institutions. AD - Division of Pediatric Pulmonary and Sleep Medicine, University of California, Los Angeles (UCLA), Los Angeles, CA, USA. Division of Hospitalist Medicine, UCSD, Rady Children's Hospital, San Diego, CA, USA. Rady Children's Hospital, San Diego, CA, USA. Division of Pediatric Infectious Disease, UCLA, Los Angeles, CA, USA; Department of Pediatrics, UCSD, Rady Children's Hospital, San Diego, CA, USA. UCSD Clinical and Translational Research Institute, San Diego, CA, USA. Pediatrics, UCSD School of Medicine, San Diego, CA, USA. AN - 28286527 AU - Ross, M. K. AU - Doshi, A. AU - Carrasca, L. AU - Pian, P. AU - Auger, J. AU - Baker, A. AU - Proudfoot, J. A. AU - Pian, M. S. C2 - PMC5329665 DO - 10.1155/2017/7568091 DP - NLM ET - 2017/03/14 LA - eng N1 - 1687-9759 Ross, Mindy K Orcid: 0000-0001-7974-4309 Doshi, Ami Carrasca, London Pian, Patricia Auger, JoAnne Baker, Amira Proudfoot, James A Pian, Mark S UL1 TR000100/TR/NCATS NIH HHS/United States Journal Article Int J Pediatr. 2017;2017:7568091. doi: 10.1155/2017/7568091. Epub 2017 Feb 12. PY - 2017 SN - 1687-9740 (Print) 1687-9740 SP - 7568091 ST - Interactive Palliative and End-of-Life Care Modules for Pediatric Residents T2 - Int J Pediatr TI - Interactive Palliative and End-of-Life Care Modules for Pediatric Residents VL - 2017 ID - 4179 ER - TY - JOUR AB - Poor emotional awareness (EA) seems to play an important role in the aetiology of functional somatic complaints featuring pain as a form of somatisation. The aim of this study was to shed more light on this relationship by investigating the links between pain, somatisation, and emotional awareness in a nonclinical population of 445 children aged 6-10. Assessing pain through the Children's Somatisation Inventory (CSI), a very high percentage of the entire sample complained of experiencing pain at least one site (84.07%) over the preceding 2 weeks. Although no difference in the prevalence of pain (whole) was found when the sample was subdivided by Levels of Emotional Awareness Scale-Children (LEAS-C), a relationship between low level of LEAS-Self and prevalence of headache (H) was detected (chi 2=7.69, p=0.02). LEAS (Self) was correlated with the intensity of back pain (BP) (r=-0.12; p<0.05), H(r=-0.12; p<0.05) but not with abdominal pain (AP). Pain worsened QoL, and the greatest negative correlation with total KidScreen-10 was found for abdominal pain (r=-0.14; p<0.01). Our results suggest that low EA is a predictor of somatisation, BP severity, H, and severity of pain in general, but not AP. AN - WOS:000451206000001 AU - Rossi, M. AU - Bruno, G. AU - Chiusalupi, M. AU - Ciaramella, A. C7 - 4316234 DO - 10.1155/2018/4316234 N1 - Rossi, M. Bruno, G. Chiusalupi, M. Ciaramella, A. 2090-1550 PY - 2018 SN - 2090-1542 ST - Relationship between Pain, Somatisation, and Emotional Awareness in Primary School Children T2 - Pain Research and Treatment TI - Relationship between Pain, Somatisation, and Emotional Awareness in Primary School Children UR - ://WOS:000451206000001 VL - 2018 ID - 2044 ER - TY - JOUR AB - OBJECTIVE: This study examined the relationship of level of educational (LOE) achievement to pain experience, affective disturbance, and perceived disability among women with chronic pelvic pain presenting for pain treatment. METHODS: 187 patients completed a battery of self-report inventories assessing pain, psychological status, and functional ability. Educational attainment was stratified across five levels from "less than high school" to "graduate/professional school." RESULTS: Significant inverse associations were found between lower educational achievement and more severe pain, somatic preoccupation, emotional suffering and guardedness, and functional impairment. No differences were obtained across the groups for age, duration of pain, or symptoms of depression. CONCLUSIONS: These data provide support for the importance of socioeconomic factors, particularly LOE, in furthering our understanding of the morbidity observed among women suffering chronic pelvic pain. AD - Department of Physical Medicine and Rehabilitation, University of Michigan Health System, Ann Arbor, MI 48109, USA. randyr@umich.edu AN - 11595244 AU - Roth, R. S. AU - Punch, M. R. AU - Bachman, J. E. DA - Oct DO - 10.1016/s0022-3999(01)00242-2 DP - NLM ET - 2001/10/12 IS - 4 KW - Adult Affective Symptoms/diagnosis/psychology Chronic Disease *Disability Evaluation *Educational Status Female Humans Pelvic Pain/*psychology Personality Inventory Risk Factors Socioeconomic Factors LA - eng N1 - Roth, R S Punch, M R Bachman, J E Journal Article England J Psychosom Res. 2001 Oct;51(4):563-9. doi: 10.1016/s0022-3999(01)00242-2. PY - 2001 SN - 0022-3999 (Print) 0022-3999 SP - 563-9 ST - Educational achievement and pain disability among women with chronic pelvic pain T2 - J Psychosom Res TI - Educational achievement and pain disability among women with chronic pelvic pain VL - 51 ID - 3589 ER - TY - JOUR AB - Pain in children and adolescents has been identified in the international literature as an important public health problem. According to international estimates, 15-25% of all children and adolescents suffer from recurrent or chronic pain. Headaches, musculoskeletal pain and abdominal pain account for most of the recurrent pain complaints reported by children and adolescents; pain in multiple localizations is frequent. Children and adolescents affected by pain complaints report interference with their hobbies, day-to-day activities, absence from school, and the use of healthcare services due to pain. There is an urgent need for development of (1) preventive strategies to reduce the prevalence of recurrent and/or persistent pain in children and (2) therapeutic strategies aimed at avoiding chronicity of pain complaints of children and adolescents in adulthood. AN - WOS:000240776300002 AU - Roth-Isigkeit, A. DA - Aug DO - 10.1007/s00112-006-1374-8 IS - 8 N1 - Roth-Isigkeit, A. 1433-0474 PY - 2006 SN - 0026-9298 SP - 741-+ ST - On epidemiology of persistent and/or recurrent pain T2 - Monatsschrift Kinderheilkunde TI - On epidemiology of persistent and/or recurrent pain UR - ://WOS:000240776300002 VL - 154 ID - 2726 ER - TY - JOUR AB - Factors that have led to the increasing prevalence of back pain amongst children and adolescents living in industrialized nations are mostly unknown. The following literature review was aimed at determining. the risk factors for back pain amongst children and adolescents. We searched both PUBMED and MEDLINE between the years 1985 and 2003 for the keywords "children or adolescents" and "back pain" Only data published in original articles were used. The risk for suffering back pain is influenced by physical, behavioural, emotional and social factors. The effects of physical activity, sitting, muscle status, weight of schoolbags, exercise, television and computer use, as well as age and gender on the development of back pain in children and adolescents were examined. Associations between continuous or recurring back pain and psychosocial factors (lifestyle, emotional factors, social relationships) could be demonstrated. There was no relationship between changes of the spine seen by radiological tests and the development of chronic back pain. Longitudinal epidemiological studies are urgently needed to delineate the risk factors for the development as well as the natural history of chronic back pain in the young. AN - WOS:000234097800011 AU - Roth-Isigkeit, A. AU - Schwarzenberger, J. AU - Baumeier, W. AU - Meier, T. AU - Lindig, M. AU - Schmucker, P. DA - Nov DO - 10.1007/s00482-004-0379-2 IS - 6 N1 - Roth-Isigkeit, A Schwarzenberger, J Baumeier, W Meier, T Lindig, M Schmucker, P 1432-2129 PY - 2005 SN - 0932-433X SP - 535-543 ST - Risk factors for back pain in children and adolescents T2 - Schmerz TI - Risk factors for back pain in children and adolescents UR - ://WOS:000234097800011 VL - 19 ID - 2752 ER - TY - JOUR AB - AIM: The aim of this study was to investigate the prevalence of pain and characteristics of pain (frequency, duration, intensity) among children and adolescents and to compare them across different age and gender groups. METHODS: 735 children and adolescents aged 10-18 y from schools in the Luebeck region of Germany were surveyed using a modified German version of the self-completion pain questionnaire of Perquin and co-workers. RESULTS: 715 out of 735 questionnaires (97.3%) were returned completed. Pain during the preceding 3 mo was reported by 85.3% (n = 610) of the respondent children and adolescents. The prevalence of pain increased with age. The most common complaints were headache (65.6%), abdominal pain (47.7%), limb pain (46.4%) and back pain (38.6%). A pain duration of longer than 3 mo was reported by 45.5% (35.4% for longer than 6 mo). Pain once a week or more frequently was reported by 33.7% of children and adolescents. CONCLUSION: Almost half of the surveyed children and adolescents had suffered complaints for longer than 3 mo. The experience of pain in general and especially pain with a duration of longer than 3 mo is very common in children and adolescents, and requires further attention. Further studies are necessary to investigate the natural course, functional implications and prognosis due to pain complaints in children and adolescents. AD - University of Schleswig-Holstein, Campus Luebeck, Department of Anaesthesia, Ratzeburger Allee 160, D-23538 Luebeck, Germany. isigkeit@medinf.mu-luebeck.de AN - 15046285 AU - Roth-Isigkeit, A. AU - Thyen, U. AU - Raspe, H. H. AU - Stöven, H. AU - Schmucker, P. DA - Feb DP - NLM ET - 2004/03/30 IS - 2 KW - Adolescent Age Distribution Child Female Germany/epidemiology Humans Male Pain/*epidemiology/etiology Pain Measurement Periodicity Prevalence Recurrence Severity of Illness Index Surveys and Questionnaires LA - eng N1 - Roth-Isigkeit, A Thyen, U Raspe, H H Stöven, H Schmucker, P Journal Article Norway Acta Paediatr. 2004 Feb;93(2):258-63. PY - 2004 SN - 0803-5253 (Print) 0803-5253 SP - 258-63 ST - Reports of pain among German children and adolescents: an epidemiological study T2 - Acta Paediatr TI - Reports of pain among German children and adolescents: an epidemiological study VL - 93 ID - 3266 ER - TY - JOUR AB - Objectives. Pain among children and adolescents has been identified as an important public health problem. Most studies evaluating recurrent or chronic pain conditions among children have been limited to descriptions of pain intensity and duration. The effects of pain states and their impact on daily living have rarely been studied. The objective of this study was to investigate the impact of perceived pain on the daily lives and activities of children and adolescents. In addition, we sought to delineate self-perceived triggers of pain among children and adolescents. In this study, we ( 1) document the 3-month prevalence of painful conditions among children and adolescents, ( 2) delineate their features ( location, intensity, frequency, and duration), ( 3) describe their consequences ( restrictions and health care utilization), and ( 4) elucidate factors that contribute to the occurrence of pain episodes among young subjects. Methods. The study was conducted in 1 elementary school and 2 secondary schools in the district of Ostholstein, Germany. Children and adolescents, as well as their parents/ guardians, were contacted through their school administrators. The teachers distributed an information leaflet, explaining the conduct and aim of the study, to the parents a few days before the official enrollment of the youths in the study. Parents of children in grades 1 to 4 of elementary school were asked to complete the pain questionnaire for their children at home, whereas children from grade 5 upward completed the questionnaire on their own during class, under the supervision of their teachers. The response rate was 80.3%. As previously stated, chronic pain was defined as any prolonged pain that lasted a minimum of 3 months or any pain that recurred throughout a minimal period of 3 months. The children and adolescents were surveyed with the Luebeck Pain-Screening Questionnaire, which was specifically designed for an epidemiologic study of the characteristics and consequences of pain among children and adolescents. The questionnaire evaluates the prevalence of pain in the preceding 3 months. The body area, frequency, intensity, and duration of pain are addressed by the questionnaire. In addition, the questionnaire inquires about the private and public consequences of pain among young subjects. Specifically, the questionnaire aims to delineate the self-perceived factors for the development and maintenance of pain and the impact of these conditions on daily life. Results. Of the 749 children and adolescents, 622 (83%) had experienced pain during the preceding 3 months. A total of 30.8% of the children and adolescents stated that the pain had been present for > 6 months. Headache (60.5%), abdominal pain (43.3%), limb pain (33.6%), and back pain (30.2) were the most prevalent pain types among the respondents. Children and adolescents with pain reported that their pain caused the following sequelae: sleep problems (53.6%), inability to pursue hobbies (53.3%), eating problems (51.1%), school absence (48.8%), and inability to meet friends (46.7%). The prevalence of restrictions in daily living attributable to pain increased with age. A total of 50.9% of children and adolescents with pain sought professional help for their conditions, and 51.5% reported the use of pain medications. The prevalence of doctor visits and medication use increased with age. Weather conditions (33%), illness (30.7%), and physical exertion (21.9%) were the most frequent self-perceived triggers for pain noted by the respondents. A total of 30.4% of study participants registered headache as the most bothersome pain, whereas 12.3% cited abdominal pain, 10.7% pain in the extremities, 8.9% back pain, and 3.9% sore throat as being most bothersome. A total of 35.2% of children and adolescents reported pain episodes occurring > 1 time per week or even more often. Health care utilization because of pain differed among children and adolescents according to the location of pain. Children and adolescents with back pain (56.7%), limb pain (55.0%), and abdominal pain ( 53.3%) visited a doctor more often than did those with headache (32.5%). In contrast, children and adolescents with headache (59.2%) reported taking medication because of pain more often than did those with back pain (16.4%), limb pain (22.5%), and abdominal pain (38.0%). The prevalence of self-reported medication use and doctor visits because of pain increased significantly with age (chi(2) test). The prevalence of self-reported medication use was significantly higher among girls than among boys of the same age, except between the ages of 4 and 9 years (chi(2) test). The prevalence of restrictions in daily activities varied among children and adolescents with different pain locations; 51.1% of children and adolescents with abdominal pain and 43.0% with headache but only 19.4% with back pain reported having been absent from school because of pain. The prevalence of restrictions attributable to pain was significantly higher among girls than among boys of the same age, except between the ages of 4 and 9 years (chi(2) test). The self-reported triggers for pain varied between girls and boys. Girls stated more often than boys that their pain was triggered by weather conditions (39% vs 25%), illness (eg, common cold or injury) (35.9% vs 23.9%), anger/disputes (20.9% vs 11.9%), family conditions (12.1% vs 5.2%), and sadness (11.9% vs 3.4%). In contrast, boys stated more often than girls that their pain was triggered by physical exertion (28% vs 17.2%). We used a logistic regression model to predict the likelihood of a child paying a visit to the doctor and/or using pain medication. Health care utilization was predicted by increasing age, greater intensity of pain, and longer duration of pain but not by the frequency of pain. We used a logistic regression model to predict restrictions in daily activities. Only the intensity of pain was predictive of the degree of restrictions in daily life attributable to pain; the duration of pain and the frequency of pain episodes had no bearing on the degree to which Conclusions. More than two thirds of the respondents reported restrictions in daily living activities attributable to pain. However, 30 to 40% of children and adolescents with pain reported moderate effects of their pain on school attendance, participation in hobbies, maintenance of social contacts, appetite, and sleep, as well as increased utilization of health services because of their pain. Restrictions in daily activities in general and health care utilization because of pain increased with age. Girls greater than or equal to 10 years of age reported more restrictions in daily living and used more medications for their pain than did boys of the same age. We found gender-specific differences in self-perceived triggers for pain. Pain intensity was the most robust variable for predicting functional impairment in greater than or equal to 1 areas of daily life. Increasing age of the child and increasing intensity and duration of pain had effects in predicting health care utilization ( visiting a doctor and/or taking medication), whereas restrictions in daily activities were predicted only by the intensity of pain. Our results underscore the relevance of pediatric pain for public health policy. Additional studies are necessary and may enhance our knowledge about pediatric pain, to enable parents, teachers, and health care professionals to assist young people with pain management, allowing the young people to intervene positively in their conditions before they become recurrent or persistent. AN - WOS:000226725000006 AU - Roth-Isigkeit, A. AU - Thyen, U. AU - Stoven, H. AU - Schwarzenberger, J. AU - Schmucker, P. DA - Feb DO - 10.1542/peds.2004-0682 IS - 2 N1 - Roth-Isigkeit, A Thyen, U Stoven, H Schwarzenberger, J Schmucker, P 1098-4275 PY - 2005 SN - 0031-4005 SP - E152-E162 ST - Pain among children and adolescents: Restrictions in daily living and triggering factors T2 - Pediatrics TI - Pain among children and adolescents: Restrictions in daily living and triggering factors UR - ://WOS:000226725000006 VL - 115 ID - 2774 ER - TY - JOUR AN - WOS:000256194900065 AU - Rothner, A. D. AU - Tepper, S. DA - May N1 - Rothner, A. D. Tepper, S. 50th Annual Scientific Meeting of the American-Headache-Society Jun 26-29, 2008 Boston, MA Amer Headache Soc 1 PY - 2008 SN - 0017-8748 SP - S28-S28 ST - A comparison of medication overuse and school absences in children and adolescents with chronic daily headache versus new daily persistent headache T2 - Headache TI - A comparison of medication overuse and school absences in children and adolescents with chronic daily headache versus new daily persistent headache UR - ://WOS:000256194900065 VL - 48 ID - 2651 ER - TY - JOUR AB - Objective: This study explored direct and indirect associations between adolescents' somatization, parenting stress, and three parenting dimensions (warmth, psychological control, and harsh punishment). First, the associations were explored cross-sectionally. Second, significant cross-sectional links were further examined longitudinally in order to decide upon temporality. Method: A total of 1499 adolescents and one of their parents (mostly the mother) agreed to participate. Questionnaires were administered when the child was respectively 12-13 (T1), 13-14 (T2), and 14-15 (T3) years old. Adolescents reported on their somatization, parents on their parenting behavior and parenting stress. Results: Cross-sectionally, indirect links were found between all parenting dimensions and adolescents' somatization, through parenting stress. Longitudinal examination revealed two key aspects. First, parenting stress significantly predicted somatization. Higher T1 parenting stress was predictive for higher T2 and T3 somatization. When controlled for T1 parenting stress, higher T2 parenting stress (or in other words increased parenting stress at T2) was predictive for lower T3 somatization. Second, parenting stress was found to significantly predict parenting behaviors. Higher T1 parenting stress was predictive for higher T2 and T3 harsh punishment but increased parenting stress at T2 was predictive for lower harsh punishment one year later. Higher T1 parenting stress significantly predicted higher T2 psychological control. Conclusions: Clinicians should be aware that parenting stress may be a risk factor for the development of somatization in early adolescence. However, in later adolescence, increased parenting stress might be protective. AN - WOS:000331050700002 AU - Rousseau, S. AU - Grietens, H. AU - Vanderfaeillie, J. AU - Hoppenbrouwers, K. AU - Wiersema, J. R. AU - Van Leeuwen, K. DO - 10.2190/PM.46.3.b IS - 3 N1 - Rousseau, Sofie Grietens, Hans Vanderfaeillie, Johan Hoppenbrouwers, Karel Wiersema, Jan Roelf Van Leeuwen, Karla Rousseau, Sofie/AAD-9473-2020; Grietens, Hans/AAF-3465-2019; Van Leeuwen, Karla/AAF-6095-2020 Van Leeuwen, Karla/0000-0002-6628-3483; Vanderfaeillie, Johan/0000-0002-1504-1185 1541-3527 PY - 2013 SN - 0091-2174 SP - 243-270 ST - PARENTING STRESS AND DIMENSIONS OF PARENTING BEHAVIOR: CROSS-SECTIONAL AND LONGITUDINAL LINKS WITH ADOLESCENTS' SOMATIZATION T2 - International Journal of Psychiatry in Medicine TI - PARENTING STRESS AND DIMENSIONS OF PARENTING BEHAVIOR: CROSS-SECTIONAL AND LONGITUDINAL LINKS WITH ADOLESCENTS' SOMATIZATION UR - ://WOS:000331050700002 VL - 46 ID - 2390 ER - TY - JOUR AB - Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex disease that affects children and adolescents as well as adults. The etiology has not been established. While many pediatricians and other health-care providers are aware of ME/CFS, they often lack essential knowledge that is necessary for diagnosis and treatment. Many young patients experience symptoms for years before receiving a diagnosis. This primer, written by the International Writing Group for Pediatric ME/CFS, provides information necessary to understand, diagnose, and manage the symptoms of ME/CFS in children and adolescents. ME/CFS is characterized by overwhelming fatigue with a substantial loss of physical and mental stamina. Cardinal features are malaise and a worsening of symptoms following minimal physical or mental exertion. These post- exertional symptoms can persist for hours, days, or weeks and are not relieved by rest or sleep. Other symptoms include cognitive problems, unrefreshing or disturbed sleep, generalized or localized pain, lightheadedness, and additional symptoms in multiple organ systems. While some young patients can attend school, on a full or part-time basis, many others are wheelchair dependent, housebound, or bedbound. Prevalence estimates for pediatric ME/CFS vary from 0.1 to 0.5%. Because there is no diagnostic test for ME/CFS, diagnosis is purely clinical, based on the history and the exclusion of other fatiguing illnesses by physical examination and medical testing. Co-existing medical conditions including orthostatic intolerance (OI) are common. Successful management is based on determining the optimum balance of rest and activity to help prevent post-exertional symptom worsening. Medications are helpful to treat pain, insomnia, OI and other symptoms. The published literature on ME/CFS and specifically that describing the diagnosis and management of pediatric ME/CFS is very limited. Where published studies are lacking, recommendations are based on the clinical observations and practices of the authors. AN - WOS:000403746100001 AU - Rowe, P. C. AU - Underhill, R. A. AU - Friedman, K. J. AU - Gurwitt, A. AU - Medow, M. S. AU - Schwartz, M. S. AU - Speight, N. AU - Stewart, J. M. AU - Vallings, R. AU - Rowe, K. S. C7 - 121 DA - Jun DO - 10.3389/fped.2017.00121 N1 - Rowe, Peter C. Underhill, Rosemary A. Friedman, Kenneth J. Gurwitt, Alan Medow, Marvin S. Schwartz, Malcolm S. Speight, Nigel Stewart, Julian M. Vallings, Rosamund Rowe, Katherine S. PY - 2017 SN - 2296-2360 ST - Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Diagnosis and Management in Young People: A Primer T2 - Frontiers in Pediatrics TI - Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Diagnosis and Management in Young People: A Primer UR - ://WOS:000403746100001 VL - 5 ID - 2092 ER - TY - JOUR AB - The successful treatment of pediatric FBD begins during the initial interaction among the patient, family, and physician. It is important that the physician establish a trusting relationship with the family. An early introduction of the concept of functional pain in the differential diagnosis avoids later problems convincing the family that further diagnostic testing is unnecessary. If diagnostic testing is warranted to exclude an organic disorder, it is useful to explain that these tests are being performed to rule out disorders that can present similarly to FBD. Thus, the patient and family recognize that the most likely diagnosis is FBD, and treatment can begin following negative testing. Physicians must account for the role of psychosocial and medical factors that contribute to the expression of illness so as to optimize diagnosis and care. Exploration into the child's psychosocial history can identify a comorbid condition such as anxiety or depression and help guide, specific therapy with psychological interventions, medication, or both. In cases where the abdominal pain is affecting the child's activities of daily living, such as school performance, referral to a psychologist skilled in the use of techniques such as cognitive behavioral therapy may be useful. Symptom-directed pharmacologic therapy can be useful in selected cases. AD - Medical College of Wisconsin, Children's Hospital of Wisconsin, USA. AN - 14999943 AU - Rudolph, C. D. AU - Miranda, A. DA - Feb DO - 10.3928/0090-4481-20040201-09 DP - NLM ET - 2004/03/06 IS - 2 KW - Abdominal Pain/classification/diagnosis/physiopathology/*therapy Behavior Therapy Child Chronic Disease Complementary Therapies Diet Family Therapy Humans LA - eng N1 - Rudolph, Colin D Miranda, Adrian Journal Article Review United States Pediatr Ann. 2004 Feb;33(2):105-12. doi: 10.3928/0090-4481-20040201-09. PY - 2004 SN - 0090-4481 (Print) 0090-4481 SP - 105-12 ST - Treatment options for functional abdominal pain T2 - Pediatr Ann TI - Treatment options for functional abdominal pain VL - 33 ID - 3142 ER - TY - JOUR AB - Ulcerative colitis (UC) and Crohn disease (CD) are chronic intestinal inflammatory diseases that can present as bloody diarrhea, abdominal pain, and malnutrition. Collectively, these disorders are referred to as inflammatory bowel disease (IBD). All patients with IBD share a common pathophysiology. However, there are a number of developmental, psychosocial, and physiologic issues that are unique to the approximate, equals 20% of patients that present during childhood or adolescence. These include the possibility of disease-induced delays in linear growth or physical development, differences in drug dosing, and the changes in social and cognitive development that occur as children move from school-age years into adolescence and early adulthood. Gastroenterologists caring for these children must therefore develop an optimal regimen of pharmacologic therapies, nutritional management, psychologic support, and properly timed surgery (when necessary) that will maintain disease remission, minimize disease and drug-induced adverse effects, and optimize growth and development. This article reviews current approaches to the management of patients with UC and CD and highlights issues specific to the treatment of children with IBD. The principal medical therapies used to induce disease remission in patients with UC are aminosalicylates (for mild disease), corticosteroids (for moderate disease), and cyclosporine (ciclosporin) (for severe disease). If a patient responds to the induction regimen, maintenance therapies that are used to prevent disease relapse include aminosalicylates, mercaptopurine, and azathioprine. Colectomy with creation of an ileal pouch anal anastomosis (J pouch) has become the standard of care for patients with severe or refractory colitis and results in an improved quality of life in most patients. Therefore, the risks associated with using increasingly potent immunosuppressant agents must be balanced in each case against a patient's desire to retain their colon and avoid a temporary or potentially permanent ileostomy. Decisions about drug therapy in the management of patients with CD are more complex and depend on both the location (e.g. gastroduodenal vs small intestinal vs colonic), as well as the behavior of the disease (inflammatory/mucosal vs stricturing vs perforating) in a given patient. Induction therapies for CD typically include aminosalicylates and antibiotics (for mild mucosal disease), nutritional therapy (including elemental or polymeric formulas), corticosteroids (for moderate disease), and infliximab (for corticosteroid-resistant or fistulizing disease). Aminosalicylates, mercaptopurine, azathioprine, methotrexate, and infliximab can be used as maintenance therapies. Because surgical treatment of CD is not curative, it is typically reserved for those patients either with persistent symptoms and disease limited to a small section of the intestine (e.g. the terminal ileum and cecum) or for the management of complications of the disease including stricture or abdominal abscess. When surgery is necessary, maintenance medications administered postoperatively will postpone recurrence. Patients with UC and CD are at risk for the development of micronutrient deficiencies (including folate, iron, and vitamin D deficiencies) and require close nutritional monitoring. In addition, patients with UC and CD involving the colon are at increased risk of developing colon cancer, and should be enrolled into a colonoscopy surveillance program after 8-10 years of disease duration. AD - Center for Inflammatory Bowel Diseases, Combined Program in Gastroenterology and Nutrition, Children's Hospital, Boston, Massachusetts 02115, USA. paul.rufo@childrens.harvard.edu AN - 17037946 AU - Rufo, P. A. AU - Bousvaros, A. DO - 10.2165/00148581-200608050-00002 DP - NLM ET - 2006/10/14 IS - 5 KW - Anti-Inflammatory Agents/therapeutic use Child Colitis, Ulcerative/diagnosis/epidemiology/physiopathology/therapy Crohn Disease/diagnosis/epidemiology/physiopathology/therapy Female Gastrointestinal Agents/therapeutic use Humans Immunosuppressive Agents/therapeutic use Inflammatory Bowel Diseases/diagnosis/epidemiology/*therapy Nutrition Disorders/complications Probiotics/therapeutic use LA - eng N1 - Rufo, Paul A Bousvaros, Athos Journal Article Research Support, Non-U.S. Gov't Review Switzerland Paediatr Drugs. 2006;8(5):279-302. doi: 10.2165/00148581-200608050-00002. PY - 2006 SN - 1174-5878 (Print) 1174-5878 SP - 279-302 ST - Current therapy of inflammatory bowel disease in children T2 - Paediatr Drugs TI - Current therapy of inflammatory bowel disease in children VL - 8 ID - 4003 ER - TY - JOUR AB - Migraine is one of the most common pain symptoms in children. Indeed, a high percentage of adult migraine patients report to have suffered from recurrent headache during the childhood. In particular, children could experience the so-called childhood periodic syndromes (such as cyclic vomiting, abdominal migraine, and benign paroxysmal vertigo) that have been usually considered precursors of migraine or they could develop overt migraine headaches. However, typical cohort of migraine symptoms could be absent and children could not achieve all clinical features necessary for a migraine attack diagnosis according to classification criteria. Nevertheless, migraine is characterized also in childhood by a significant negative impact on the quality of life and a high risk of developing chronic and persistent headache in adulthood. Several studies have emphasized the role of different risk factors for migraine in children. Among these, obesity and overweight, particular food or the regular consumption of alcohol or caffeine, dysfunctional family situation, low level of physical activity, physical or emotional abuse, bullying by peers, unfair treatment in school, and insufficient leisure time seem to be strictly related to migraine onset or progression. Consequently, both identification and avoidance of triggers seem to be mandatory in children with migraine and could represent an alternative approach to the treatment of migraine abstaining from pharmacologic therapies. AN - WOS:000370812300002 AU - Russo, A. AU - Bruno, A. AU - Trojsi, F. AU - Tessitore, A. AU - Tedeschi, G. C7 - 9 DA - Feb DO - 10.1007/s11916-016-0539-y IS - 2 N1 - Russo, Antonio Bruno, Antonio Trojsi, Francesca Tessitore, Alessandro Tedeschi, Gioacchino Bruno, Antonio/AAN-4462-2021 Bruno, Antonio/0000-0003-0976-3410 1534-3081 PY - 2016 SN - 1531-3433 ST - Lifestyle Factors and Migraine in Childhood T2 - Current Pain and Headache Reports TI - Lifestyle Factors and Migraine in Childhood UR - ://WOS:000370812300002 VL - 20 ID - 2185 ER - TY - JOUR AB - Background: This systematic review is the first step in a study investigating the resilience methods and processes in families of children with juvenile idiopathic arthritis. In particular, this review will focus on chronic or persistent pain, as a common symptom of juvenile idiopathic arthritis, which is the most common rheumatic disease in childhood. The experience of persistent pain can add to the functional disability associated with juvenile idiopathic arthritis. Resilience has relevance to all areas of paediatric psychology, and targeted attention to child, sibling, and parent strengths within the context of paediatric chronic pain and juvenile idiopathic arthritis in particular will augment the field on numerous levels. The objective is to determine which resilience processes are associated with a favourable quality of life in terms of academic, communication, emotional, interpersonal, physical, psychological, and social well-being in families of children with chronic pain associated with JIA. Methods/design: This systematic review will be conducted and reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement and the PRESS (Peer Review of Electronic Search Strategies) guideline. Longitudinal, cross-sectional, and treatment studies written in English will be included, as will grey literature (i.e. conference abstracts and dissertations). Studies involving participants who are 6-18 years of age, have been diagnosed with juvenile idiopathic arthritis, are experiencing chronic pain, and are currently undergoing treatment will be included regardless of sex, arthritis type, and type of treatment. Studies including siblings who are 6-18 years of age and the patient's parents will be included. Discussion: Research exploring resilience within the adult population is accruing. Shifting our focus to protective factors of resilience in the context of paediatric chronic pain, specifically juvenile idiopathic arthritis, is a novel and promising pursuit that has the potential to optimize and inform future clinical practice and interventions. A better understanding of the role of reliance in family adaptation will facilitate the development of more effective treatment approaches and lay the foundation for more effective self-management in paediatric chronic pain. Systematic review registration: This protocol is registered with the International Prospective Register of Systematic Reviews (PROSPERO) database (registration: CRD42016047226). AN - WOS:000453154500221 AU - Saetes, S. AU - Hynes, L. AU - McGuire, B. E. AU - Caes, L. C7 - 221 DO - 10.1186/s13643-017-0619-z N1 - Saetes, Sophia Hynes, Lisa McGuire, Brian E. Caes, Line 2046-4053 PY - 2017 ST - Family resilience and adaptive coping in children with juvenile idiopathic arthritis: protocol for a systematic review T2 - Systematic Reviews TI - Family resilience and adaptive coping in children with juvenile idiopathic arthritis: protocol for a systematic review UR - ://WOS:000453154500221 VL - 6 ID - 2124 ER - TY - JOUR AB - BACKGROUND AND AIM: The prevalence of functional gastrointestinal disorders (FGID) in adolescents and their relationship to quality of school life (QOSL) are not fully understood. This study investigated the relationship between FGID and QOSL. METHODS: Adolescents (10-17 years) were recruited from 40 schools. FGID diagnoses were based on the Questionnaire on Pediatric Gastrointestinal Symptoms-Rome III version (QPGS-RIII). QOSL was evaluated by a questionnaire and calculated as the QOSL score. RESULTS: Five hundred and fifty-two of the 3976 students (13.9%) met the FGID criteria for one or more diagnoses according to the QPGS-RIII: 12.3% met the criteria for one, 1.5% for two or more. Irritable bowel syndrome (IBS) was the most common diagnosis (5.9%) followed by functional abdominal pain (3.1%). The prevalence of FGID was significantly higher in the female students in comparison to male students (P < 0.01). The prevalence of FGID was 9.5% in elementary school, 15.4% in junior high school, 26.0% in high school students, respectively. The prevalence of FGID was significantly increased with age (P < 0.01). The QOSL score of the patients with FGID was 10.9 ± 4.5 and that without FGID was 8.2 ± 2.8, respectively. The QOSL score of the patients with FGID was significantly worse than those without FGID (P < 0.01). The QOSL scores with IBS, aerophagia, and cyclic vomiting syndrome were significantly worse among the FGID (P < 0.01). CONCLUSIONS: The prevalence of FGID in adolescents was relatively high. The presences of FGID worsen the QOSL score. Medical intervention and/or counseling are needed for such students to improve the QOSL. AD - Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan. AN - 22988951 AU - Sagawa, T. AU - Okamura, S. AU - Kakizaki, S. AU - Zhang, Y. AU - Morita, K. AU - Mori, M. DA - Feb DO - 10.1111/j.1440-1746.2012.07257.x DP - NLM ET - 2012/09/20 IS - 2 KW - Abdominal Pain/epidemiology/psychology Adolescent Aerophagy/epidemiology/psychology Age Factors Analysis of Variance Child Cost of Illness Female Gastrointestinal Diseases/diagnosis/epidemiology/*psychology Humans Irritable Bowel Syndrome/epidemiology/psychology Japan/epidemiology Male Prevalence *Quality of Life Severity of Illness Index Sex Factors Students/*psychology Surveys and Questionnaires Vomiting/epidemiology/psychology LA - eng N1 - 1440-1746 Sagawa, Toshihiko Okamura, Shinichi Kakizaki, Satoru Zhang, Yajing Morita, Kyoko Mori, Masatomo Comparative Study Journal Article Research Support, Non-U.S. Gov't Australia J Gastroenterol Hepatol. 2013 Feb;28(2):285-90. doi: 10.1111/j.1440-1746.2012.07257.x. PY - 2013 SN - 0815-9319 SP - 285-90 ST - Functional gastrointestinal disorders in adolescents and quality of school life T2 - J Gastroenterol Hepatol TI - Functional gastrointestinal disorders in adolescents and quality of school life VL - 28 ID - 3713 ER - TY - JOUR AB - Magnitude of recurrent headache (RHA) is not well explored among school-children (schoolers) particularly in developing countries like Bangladesh, though recent literature reveals that RHA connotes serious public health implication(s) particularly in schoolers in resource constraint countries. To study age and gender-dependent correlates of RHA among secondary-level schoolers and to determine if these remains its risk-factors. Cross-sectional population based respondent-dependent study employing direct interviews using pre-tested open and closed-ended questionnaire following ICHD-II (2004) diagnostic criteria. Overall, 17% RHA was observed among 1499 schoolers surveyed initially, being more in pubertal/adolescents (13-15 years) than pre-pubertal (11-12 years) ones. Of screened-out 255 RHA positive cases, migraine (MHA) was observed in 55.3% while tension-type-headache (TTH) in 19.6% schoolers. RHA demonstrated a steady-inclining trend with schooler's age. Gender difference was obvious in MHA (p<0.001) but not in TTH (p<0.31). Pubertal schoolers (OR=8.75) and boys (OR=1.8) remained at greater risk for migraine but less risky for TTH. Mass-awareness program is imperative to prevent RHA among schoolers towards progressing it into chronicity, psycho-socially handicapped and economically burdened. Further in-depth studies warrant prudent data to examine its long-term risks/underlying factors involving more diverse population (school-children) from different geographical areas and cultural contexts. AD - Dr Narayan Chandra Saha, Associate Professor, Child Neurology Division, Institute of Neurological Sciences, Agargaon, Dhaka, Bangladesh. AN - 29208872 AU - Saha, N. C. AU - Anwar, K. S. AU - Mollah, A. H. AU - Akhter, S. AU - Amin, M. R. AU - Mollah, A. A. DA - Oct DP - NLM ET - 2017/12/07 IS - 4 KW - Adolescent Bangladesh Child Cross-Sectional Studies Headache Humans Male *Migraine Disorders/epidemiology Risk Factors *Tension-Type Headache/epidemiology LA - eng N1 - 2408-8757 Saha, N C Anwar, K S Mollah, A H Akhter, S Amin, M R Mollah, A A Journal Article Bangladesh Mymensingh Med J. 2017 Oct;26(4):831-839. PY - 2017 SN - 1022-4742 SP - 831-839 ST - Age and Gender-dependent Correlates as Risk Factors of Recurrent Headache among Bangladeshi Secondary School Children T2 - Mymensingh Med J TI - Age and Gender-dependent Correlates as Risk Factors of Recurrent Headache among Bangladeshi Secondary School Children VL - 26 ID - 3090 ER - TY - JOUR AB - INTRODUCTION: Dental pain is a major public health problem and one of the consequences of oral diseases which requires significant adjustments in life management leading to decreased quality of life. OBJECTIVE: To assess prevalence of dental pain and its impact on daily life and to explore its relationship with oral health behavior and clinical oral status among 10-15 year old school children attending oral health promoting schools. METHOD: This cross sectional study was conducted in 6 schools serving low -middle socio economic strata in Bangalore, India. A total of 1237 children were surveyed for history of dental pain during past 3 month. Participants who reported dental pain completed self-reported oral health behaviour and Child dental pain questionnaire. Clinical oral examination included assessment of dental caries, periodontal status. Data was analyzed using t - test, Chi-square test, ANOVA and Regression Analysis. RESULTS: Prevalence of dental pain was 15.6% (n = 194). Among children with pain, 17%, 43% and 40% reported mild, moderate and severe pain. Impact on daily activities was reported by 66%. Mean DMFT and DMFS was 1.80 and 2.11 Mean deft and defs was 2.47 and 3.41. Multiple logistic regression revealed that severity and impact of dental pain was associated with gender, frequency of tooth brushing, consumption of sweets and deciduous dental caries experience. CONCLUSION: Prevalence of Dental pain is associated with brushing behavior, consumption of sweets and deciduous dental caries experience, showing need for further attention to these conditions and a need to strengthen preventive and therapeutic dental services. AU - Saheer, Abdul AU - Kousalya, Pallavi Swami AU - Raju, Rekha AU - Gubbihal, Radha DA - 2015/12// DO - 10.4103/2231-0762.172948 DP - PubMed IS - Suppl 2 J2 - J Int Soc Prev Community Dent KW - Children dental pain oral health LA - eng PY - 2015 SN - 2231-0762 SP - S101-106 ST - Dental pain among 10-15 year old children attending oral health promoting schools T2 - Journal of International Society of Preventive & Community Dentistry TI - Dental pain among 10-15 year old children attending oral health promoting schools: A cross-sectional study UR - http://www.ncbi.nlm.nih.gov/pubmed/26942112 VL - 5 ID - 79 ER - TY - JOUR AB - Objective The aim of this qualitative study was to elucidate the life situation and psychosocial processes of living with chronic pain in children suffering from juvenile chronic arthritis (JCA). Methods Taped open qualitative interviews with 22 children (aged 6-17 years) were transcribed verbatim and analysed using the comparative method for grounded theory. Results A core category, labelled oscillating between hope and despair, was identified and related to four additional categories labelled disturbed order, dependency, ambivalence and uncertainty about the future. There were relationships between the children's subjective experience of pain and their experiences of disturbed order in daily life,dependency on treatment, health care and significant others, ambivalence related to environmental reactions and uncertainty about the future. Chronic pain and disease control the children's lives and lead to restricted participation in social life. Conclusions Chronic pain is a substantial problem for children with JCA, which must be considered in health care. The pain affected and disturbed the children's ordinary way of life. It blocked a number of goals. Psychological and physiological processes interact in the phenomenological experience of pain, and the response of the environment elicits, maintains or decreases the experience of pain. Hopefully,the findings contribute to a deeper understanding of the life situation of children suffering from JCA and can be of importance in developing rehabilitation programmes for these children. AN - WOS:000179573900008 AU - Sallfors, C. AU - Fasth, A. AU - Hallberg, L. R. M. DA - Nov DO - 10.1046/j.1365-2214.2002.00300.x IS - 6 N1 - Sallfors, C Fasth, A Hallberg, LRM Fasth, Anders/I-1109-2019 1365-2214 PY - 2002 SN - 0305-1862 SP - 495-505 ST - Oscillating between hope and despair - a qualitative study T2 - Child Care Health and Development TI - Oscillating between hope and despair - a qualitative study UR - ://WOS:000179573900008 VL - 28 ID - 2818 ER - TY - JOUR AB - From a population of 1,503 schoolchildren, 38 15-year-old children reporting recurrent or continuous low-back pain and 38 asymptomatic controls (34 boys and 42 girls) matched for age. sex, and school class were selected for tests of spinal mobility and trunk muscle strength, and for a magnetic resonance imaging (MRI) study of the lumbar spine. In addition, the subjects were asked about leisure time physical activities in an interview preceding the measurements. Spinal muscular atrophy was the only finding that was more common among physically inactive subjects (p = 0.005). Moreover, increased occurrence of disk degeneration (DD) was observed in the low-activity group. However, the difference was not significant. Neither Scheuermann-type changes nor DD were related to spinal mobility or trunk muscle strength. Children with disk protrusion were, on the average, taller (p = 0.044), and their lumbar flexion measured by flexicurve was decreased (p = 0.043). Our results strengthen further the evidence that MRI is a sensitive measure and that imaging findings must be interpreted carefully with respect to pain and physical impairment of the lumbar spine. Furthermore, no clear evidence of the association between physical activity and early DD could be found. AN - WOS:A1993MA46400003 AU - Salminen, J. J. AU - Erkintalotertti, M. O. AU - Paajanen, H. E. K. DA - Oct DO - 10.1097/00002517-199306050-00003 IS - 5 N1 - Salminen, jj erkintalotertti, mo paajanen, hek PY - 1993 SN - 0895-0385 SP - 386-391 ST - MAGNETIC-RESONANCE-IMAGING FINDINGS OF LUMBAR SPINE IN THE YOUNG - CORRELATION WITH LEISURE-TIME PHYSICAL-ACTIVITY, SPINAL MOBILITY, AND TRUNK MUSCLE STRENGTH IN 15-YEAR-OLD PUPILS WITH OR WITHOUT LOW-BACK-PAIN T2 - Journal of Spinal Disorders TI - MAGNETIC-RESONANCE-IMAGING FINDINGS OF LUMBAR SPINE IN THE YOUNG - CORRELATION WITH LEISURE-TIME PHYSICAL-ACTIVITY, SPINAL MOBILITY, AND TRUNK MUSCLE STRENGTH IN 15-YEAR-OLD PUPILS WITH OR WITHOUT LOW-BACK-PAIN UR - ://WOS:A1993MA46400003 VL - 6 ID - 2952 ER - TY - JOUR AB - Aims: Chronic pain is a notable burden on public health, with past and present factors contributing to it. This study aimed to examine the associations between childhood adversities and chronic pain. Methods: Data on seven childhood adversities, chronic pain and disabling pain were derived from questionnaire surveys conducted in 2000, 2001 and 2002 among 40- to 60-year-old employees (response rate of 67%) of the City of Helsinki, Finland. The study included 8140 employees (80% women). Logistic regression was used in the analyses, and the results are presented as odds ratios (OR) and their 95% confidence intervals (CI). Age, sex, the father's education, the participant's education, marital status, working conditions, sleep problems and common mental disorders were included as covariates. Results: In the age-adjusted models, childhood economic difficulties (OR=1.60, 95% CI 1.41-1.81), childhood illness (OR=1.74, 95% CI 1.45-2.08), parental divorce (OR=1.26, 95% CI 1.07-1.48), parental alcohol problems (OR=1.34, 95% CI 1.18-1.52) and bullying at school or among peers (OR=1.59, 95% CI 1.37-1.89) were associated with chronic pain. Working conditions, sleep problems and common mental disorders each slightly attenuated the associations between childhood adversities and chronic pain. Childhood economic difficulties among women (OR=1.72, 95% CI 1.40-2.10), childhood illness (OR=1.40, 95% CI 1.07-1.82) and bullying at school or by peers (OR=1.91 95% CI 1.48-2.46) were also associated with disabling pain. Conclusions: Childhood adversities were associated with chronic pain in mid-life, and the associations mainly remained after adjustments. Investing in the well-being of children might prevent pain and promote well-being in mid-life. AN - WOS:000629730200001 AU - Salonsalmi, A. AU - Pietilainen, O. AU - Lahelma, E. AU - Rahkonen, O. AU - Lallukka, T. C7 - 1403494820981509 DO - 10.1177/1403494820981509 N1 - Salonsalmi, Aino Pietilainen, Olli Lahelma, Eero Rahkonen, Ossi Lallukka, Tea Pietilainen, Olli/AAO-1700-2021 1651-1905 SN - 1403-4948 ST - Contributions of childhood adversities to chronic pain among mid-life employees T2 - Scandinavian Journal of Public Health TI - Contributions of childhood adversities to chronic pain among mid-life employees UR - ://WOS:000629730200001 ID - 1764 ER - TY - JOUR AB - Aims: Chronic pain is a notable burden on public health, with past and present factors contributing to it. This study aimed to examine the associations between childhood adversities and chronic pain. Methods: Data on seven childhood adversities, chronic pain and disabling pain were derived from questionnaire surveys conducted in 2000, 2001 and 2002 among 40- to 60-year-old employees (response rate of 67%) of the City of Helsinki, Finland. The study included 8140 employees (80% women). Logistic regression was used in the analyses, and the results are presented as odds ratios (OR) and their 95% confidence intervals (CI). Age, sex, the father's education, the participant's education, marital status, working conditions, sleep problems and common mental disorders were included as covariates. Results: In the age-adjusted models, childhood economic difficulties (OR=1.60, 95% CI 1.41-1.81), childhood illness (OR=1.74, 95% CI 1.45-2.08), parental divorce (OR=1.26, 95% CI 1.07-1.48), parental alcohol problems (OR=1.34, 95% CI 1.18-1.52) and bullying at school or among peers (OR=1.59, 95% CI 1.37-1.89) were associated with chronic pain. Working conditions, sleep problems and common mental disorders each slightly attenuated the associations between childhood adversities and chronic pain. Childhood economic difficulties among women (OR=1.72, 95% CI 1.40-2.10), childhood illness (OR=1.40, 95% CI 1.07-1.82) and bullying at school or by peers (OR=1.91 95% CI 1.48-2.46) were also associated with disabling pain. Conclusions: Childhood adversities were associated with chronic pain in mid-life, and the associations mainly remained after adjustments. Investing in the well-being of children might prevent pain and promote well-being in mid-life. AD - Department of Public Health, University of Helsinki, Finland. AN - 33461395 AU - Salonsalmi, A. AU - Pietiläinen, O. AU - Lahelma, E. AU - Rahkonen, O. AU - Lallukka, T. DA - Jan 18 DO - 10.1177/1403494820981509 DP - NLM ET - 2021/01/20 KW - Adverse childhood experiences chronic pain LA - eng N1 - 1651-1905 Salonsalmi, Aino Orcid: 0000-0002-3939-2844 Pietiläinen, Olli Lahelma, Eero Rahkonen, Ossi Lallukka, Tea Orcid: 0000-0003-3841-3129 Journal Article Sweden Scand J Public Health. 2021 Jan 18:1403494820981509. doi: 10.1177/1403494820981509. PY - 2021 SN - 1403-4948 SP - 1403494820981509 ST - Contributions of childhood adversities to chronic pain among mid-life employees T2 - Scand J Public Health TI - Contributions of childhood adversities to chronic pain among mid-life employees ID - 4156 ER - TY - JOUR AB - From 10% to 15% of school-aged children experience recurring abdominal pain. This study evaluated the efficacy of a cognitive-behavioral program for the treatment of nonspecific recurrent abdominal pain (RAP) using a controlled group design. The multicomponent treatment program consisted of differential reinforcement of well behavior, cognitive coping skills training, and various generalization enhancement procedures. Multiple measures of pain intensity and pain behavior were conducted, including children's self-monitoring, parent observation, teacher observation, and observation by independent observers. Results showed that both the experimental and the control groups reduced their levels of pain. However, the treated group improved more quickly, the effects generalized to the school setting, and a larger proportion of subjects were completely pain-free by 3-months follow-up (87.5% vs. 37.5%). There was no evidence for any negative side effects of treatment. AN - 2708618 AU - Sanders, M. R. AU - Rebgetz, M. AU - Morrison, M. AU - Bor, W. AU - Gordon, A. AU - Dadds, M. AU - Shepherd, R. DA - Apr DO - 10.1037//0022-006x.57.2.294 DP - NLM ET - 1989/04/01 IS - 2 KW - *Abdomen Behavior Therapy/*methods Child *Cognition Female *Generalization, Psychological Humans Male Pain/psychology *Pain Management Recurrence LA - eng N1 - Sanders, M R Rebgetz, M Morrison, M Bor, W Gordon, A Dadds, M Shepherd, R Journal Article United States J Consult Clin Psychol. 1989 Apr;57(2):294-300. doi: 10.1037//0022-006x.57.2.294. PY - 1989 SN - 0022-006X (Print) 0022-006x SP - 294-300 ST - Cognitive-behavioral treatment of recurrent nonspecific abdominal pain in children: an analysis of generalization, maintenance, and side effects T2 - J Consult Clin Psychol TI - Cognitive-behavioral treatment of recurrent nonspecific abdominal pain in children: an analysis of generalization, maintenance, and side effects VL - 57 ID - 3416 ER - TY - JOUR AB - OBJECTIVES: Prevalence of chronic migraine in children can reach 7.7%, causing decreased school performance, difficulty with extracurricular activities (including sports, theater, or music), and changes in sleep and mood. Many studies confirm that botulinum toxin type A injections effectively alleviate chronic migraines in adults; however, the literature regarding children is sparse. This study aims to analyze the safety and effectiveness of botulinum type A injections in a group of pediatric patients diagnosed with chronic migraines in a pediatric pain clinic. METHODS: In this retrospective (2013-2018) study, the effects of botulinum toxin type A injections were analyzed using data from 65 pediatric patients diagnosed with chronic migraines. The study group ranged from 11 to 18 years of age. A pediatric pain management physician administered the botulinum using the Phase 3 Research Evaluating Migraine Prophylaxis Therapy program protocol and followed the pain pattern. Dosages, tolerance, and side effects were measured. RESULTS: In this study, 74% of the patients tried more than 6 medications before the injections. There was a decrease in the visual analog scale score of 5.2 ± 2.2 points upon 6-week follow-up. The mean amount of medication used was 173.2 ± 35 units, and patients received an average of 2.8 ± 1.1 units/kg. Adverse events include one patient who developed dizziness and another who had low-grade fevers with enlarged cervical lymph nodes; both resolved within few minutes. CONCLUSIONS: This study supports the use of botulinum type A for chronic migraines in pediatric patients. Multicentered, randomized studies with larger population are needed to evaluate the long-term safety and efficacy of this therapy. AN - 33603578 AU - Santana, L. AU - Liu, C. C2 - PMC7887883 DO - 10.5863/1551-6776-26.2.151 DP - NLM ET - 2021/02/20 IS - 2 KW - botulinum toxin A headache migraine pain pediatric service mentioned in the manuscript, including grants, equipment, medications, employment, gifts, and honoraria. Both authors had full access to all the data and take responsibility for the integrity and accuracy of the data analysis. LA - eng N1 - 2331-348x Santana, Lisgelia Liu, Cherry Journal Article J Pediatr Pharmacol Ther. 2021;26(2):151-156. doi: 10.5863/1551-6776-26.2.151. Epub 2021 Feb 15. PY - 2021 SN - 1551-6776 (Print) 1551-6776 SP - 151-156 ST - Experience of Botulinum Toxin A Injections for Chronic Migraine Headaches in a Pediatric Chronic Pain Clinic T2 - J Pediatr Pharmacol Ther TI - Experience of Botulinum Toxin A Injections for Chronic Migraine Headaches in a Pediatric Chronic Pain Clinic VL - 26 ID - 4063 ER - TY - JOUR AB - OBJECTIVES: Pediatric obesity and chronic pain are 2 of the most significant public health crises affecting youth today. Despite the high number of youth experiencing both chronic pain and obesity, little research has been done examining their relationship. This study aims to both replicate and extend this research base. METHODS: A retrospective chart review of 99 patients presenting for evaluation in a pediatric pain clinic was conducted. Demographic information, including patient weight status, and self-report measures completed by both patients and their parents, including the Pain Frequency-Severity-Duration scale, the Functional Disability Inventory, and the Pain Catastrophizing Scale were examined. RESULTS: Abdominal pain was the most frequently reported primary pain diagnosis category, with headache, diffuse musculoskeletal, localized musculoskeletal, and back pain categories reported from greatest to least frequency. Results show that 29% of our sample was obese. Age was related to weight status such that older children were more likely to have a higher body mass index. Among school-aged children, a higher body mass index percentile was associated with greater parent-reported pain catastrophizing. Obese youth had higher parent-reported Functional Disability Inventory scores than those in the normal weight group. Post hoc comparisons identified that this finding was only significant for girls. Further, obese youth were more likely to have a longer pain duration than those classified as normal weight. DISCUSSION: The results of this study add to the growing literature regarding the importance of taking weight status into account when intervening with youth with chronic pain. AD - *Connecticut Children's Medical Center ‡Trinity College †University of Connecticut School of Medicine, Hartford CT. AN - 27841832 AU - Santos, M. AU - Murtaugh, T. AU - Pantaleao, A. AU - Zempsky, W. T. AU - Guite, J. W. DA - Aug DO - 10.1097/ajp.0000000000000448 DP - NLM ET - 2016/11/15 IS - 8 KW - Adolescent Analysis of Variance Body Mass Index Catastrophization Child Chronic Pain/*complications/*epidemiology Disability Evaluation Female Humans Male Obesity/*complications/*epidemiology Pain Clinics Pain Measurement Patient Care Team Prevalence Retrospective Studies Self Report Sex Factors LA - eng N1 - 1536-5409 Santos, Melissa Murtaugh, Taylor Pantaleao, Ashley Zempsky, William T Guite, Jessica W Journal Article United States Clin J Pain. 2017 Aug;33(8):738-745. doi: 10.1097/AJP.0000000000000448. PY - 2017 SN - 0749-8047 SP - 738-745 ST - Chronic Pain and Obesity Within a Pediatric Interdisciplinary Pain Clinic Setting: A Preliminary Examination of Current Relationships and Future Directions T2 - Clin J Pain TI - Chronic Pain and Obesity Within a Pediatric Interdisciplinary Pain Clinic Setting: A Preliminary Examination of Current Relationships and Future Directions VL - 33 ID - 3179 ER - TY - JOUR AB - BACKGROUND AND AIMS: Functional gastrointestinal disorders (FGIDs) are common in children. Abdominal pain (AP) is the most common gastrointestinal (GI) symptom in children. The severity of AP drives medical consultations and quality of life in adult patients with irritable bowel syndrome (IBS). Thirty-eight percent of 8- to 15-year-old schoolchildren report AP weekly with 24% of those children reporting persistence of AP >8 weeks. Despite the high prevalence of AP, only 2% of school children seek medical attention for AP. Lack of parental knowledge on their child's symptoms may constitute one of the factors affecting the low ratio of consultation in children reporting AP. The aim was to assess parental reports of AP symptoms in a population of healthy community children. METHODS: Data of 5 studies with identical methodology to assess GI symptoms in children with celiac disease (CD), cow's milk allergy (CMA), pyloric stenosis (PS), Henoch-Schönlein purpura (HSP), and stem cell transplant (SC) and their healthy siblings were reviewed: a phone questionnaire on GI symptoms and Pediatric Gastrointestinal Symptoms Rome III version questionnaire (QPGS-RIII). Inclusion criteria were healthy children 4 to 18 years of age with a sibling previously diagnosed with CD, CMA, PS, HSP, or SC. RESULTS: Data on 246 healthy children, mean age (9.8 years, range 3-24, 112 girls) were obtained. Parents reported presence of AP in the last 8 weeks before the telephone contact in 20 (8.1%) children (age range 4-18 years, 11 girls). There was no significant difference in AP prevalence between boys and girls (P = 0.64). Six children (2.4%) met QPGS-RIII diagnostic criteria for FGIDs: 3 functional abdominal pain (FAP) and 3 IBS. CONCLUSIONS: AP was common in community children. FAP was the most common FGID among healthy community children. The prevalence of AP by parental report is lower than the previously published prevalence of AP reported by children. Lack of awareness of children's symptoms may play a role in the low ratio of consultation for AP in symptomatic children. Future prospective studies should confirm our findings and investigate the factors influencing the medical consultation decision including parental awareness of children's symptoms. AD - Department of Pediatric Gastroenterology, Hepatology and Nutrition, Children's Memorial Hospital, Northwestern University, Chicago, IL 60614, USA. msaps@childrensmemorial.org AN - 22744191 AU - Saps, M. AU - Adams, P. AU - Bonilla, S. AU - Chogle, A. AU - Nichols-Vinueza, D. DA - Dec DO - 10.1097/MPG.0b013e3182662401 DP - NLM ET - 2012/06/30 IS - 6 KW - Abdominal Pain/diagnosis/*epidemiology/etiology Adolescent Awareness Celiac Disease/complications Child Child, Preschool Female Health Surveys Humans Interviews as Topic Irritable Bowel Syndrome/complications/diagnosis/*epidemiology Male Milk Hypersensitivity/complications *Parents Prevalence Purpura, Schoenlein-Henoch/complications Pyloric Stenosis/complications Reference Values Siblings Stem Cell Transplantation/adverse effects Surveys and Questionnaires LA - eng N1 - 1536-4801 Saps, Miguel Adams, Papa Bonilla, Silvana Chogle, Ashish Nichols-Vinueza, Diana Journal Article United States J Pediatr Gastroenterol Nutr. 2012 Dec;55(6):707-10. doi: 10.1097/MPG.0b013e3182662401. PY - 2012 SN - 0277-2116 SP - 707-10 ST - Parental report of abdominal pain and abdominal pain-related functional gastrointestinal disorders from a community survey T2 - J Pediatr Gastroenterol Nutr TI - Parental report of abdominal pain and abdominal pain-related functional gastrointestinal disorders from a community survey VL - 55 ID - 3911 ER - TY - JOUR AB - Background: Children with abdominal pain (AP) have worse quality of life and poorer social functioning and school attendance than their healthy peers. This is the first investigation of consultation patterns and costs of AP in South American children. Patients and Methods: All data were collected from Unidad Coronaria Movil in Montevideo, Uruguay. Diagnoses of all house calls during a 4-year period (January 2002 through December 2005) were analyzed. Variances in consultation patterns based on sex and age were investigated. Supply and personnel costs were analyzed and prorated to obtain an accurate estimate of the cost per house call and outpatient visit. Results: A total of 125,945 in-home visits and 1588 outpatient consultations were analyzed. Consultation rates for AP peaked among patients 7 to 9 years of age. Female subjects 9 to 14 years of age consulted significantly more frequently for AP than male subjects in the same age group. The average AP consultation accounted for approximately 3.8% of the per capita health care spending in Uruguay in 2005. Conclusions: AP is a global health problem that is present across ethnicities, nationalities, and geographic locations and is associated with significant health care expenditure. AN - WOS:000252620600006 AU - Saps, M. AU - Bolioli, P. AU - Espana, M. AU - Marshall, B. M. AU - Di Lorenzo, C. DA - Feb DO - 10.1097/MPG.0b013e31812e6b1f IS - 2 N1 - Saps, Miguel Bolioli, Pablo Espana, Magali Marshall, Beth M. Di Lorenzo, Carlo PY - 2008 SN - 0277-2116 SP - 159-163 ST - Cost and consultation patterns of abdominal pain in uruguayan children T2 - Journal of Pediatric Gastroenterology and Nutrition TI - Cost and consultation patterns of abdominal pain in uruguayan children UR - ://WOS:000252620600006 VL - 46 ID - 2663 ER - TY - JOUR AB - Introduction: Functional gastrointestinal disorders (FGIDs) are highly prevalent worldwide and are thought to result from the interplay of multiple factors that can vary from region to region. Nationwide studies can help understand the regional epidemiology and the pathogenesis of FGIDs. The objectives of this study were to determine the prevalence of FGIDs in school-children of Colombia and assess associated factors. Methods: A cross-sectional study was carried out at twelve private and public schools in ten cities distributed through the four main geographic regions of Colombia. School-children completed a validated questionnaire to assess functional gastrointestinal disorders according to Rome III criteria. Demographic information and past medical and family history was obtained from the parents. Results: A total of 4394/5062 (86.8%) children participated in the study, with ages ranging from 8-18 years (mean = 11.9, SD = 2.3). The percentage of children with al least on FGID was 23.7%. Disorders of defecation were the most common category FGID (11.7%) followed by abdominal pain related-functional gastrointestinal disorders (10.4%). Children have increased odds of FGIDs if they have separated parents (OR 1.22, P=0.007), attend private school (OR 1.54, P<0.001), or have nausea (OR 3.16, P<0.001). Conclusions: This large epidemiological study of pediatric FGIDs is the first to evaluate a broad cross-section of children throughout a nation in the Americas. High prevalence of FGIDs and identified associations with their likelihood are relevant when providing medical care and when planning public health efforts. (C) 2017 Hospital Infantil de Mexico Federico Gomez. Published by Masson Doyma Mexico S.A. AN - WOS:000439897100003 AU - Saps, M. AU - Moreno-Gomez, J. E. AU - Ramirez-Hernandez, C. R. AU - Rosen, J. M. AU - Velasco-Benitez, C. A. DA - Nov-Dec DO - 10.1016/j.bmhimx.2017.05.005 IS - 6 N1 - Saps, Miguel Enrique Moreno-Gomez, Jairo Rossy Ramirez-Hernandez, Carmen Rosen, John M. Velasco-Benitez, Carlos A. Rosen, John/ABH-1241-2020 Rosen, John/0000-0003-4291-3214; Velasco-Benitez, Carlos Alberto/0000-0002-4062-5326; Ramirez-Hernandez, Carmen Rossy/0000-0003-1180-9086; Velasco-Benitez, Carlos A/0000-0001-5647-3024 1665-1146 PY - 2017 SN - 0539-6115 SP - 407-412 ST - A nationwide study on the prevalence of functional gastrointestinal disorders in school-children T2 - Boletin Medico Del Hospital Infantil De Mexico TI - A nationwide study on the prevalence of functional gastrointestinal disorders in school-children UR - ://WOS:000439897100003 VL - 74 ID - 2064 ER - TY - JOUR AB - Objectives To determine prevalence for functional gastrointestinal disorders (FGIDs) in Colombian school children using the Questionnaire on Pediatric Gastrointestinal Symptoms-Rome III Version (QPGS-III) and to determine possible risk factors. Study design The QPGS-III was translated into Spanish then reverse translated by a team of bilingual physicians. Focus groups of Colombian children were conducted to assure understanding of the Spanish version. Children at 1 public school and 2 private schools in Pasto, Colombia were invited to participate in a prevalence study using the translated questionnaire. Results A total of 373 children (95 private school, 278 public school), with mean age 9.9 years completed the QPGS-III. Twenty-nine percent of children were diagnosed with FGIDs. FGIDs were more common in females (OR, 1.63; 95% CI, 1.04-2.56). Functional constipation (14%) was the most common FGID. Irritable bowel syndrome was the most common abdominal pain-related FGID (5.4%). Abdominal migraine (1%) and cyclic vomiting syndrome (0.3%) were the least common FGIDs. Conclusion FGIDs are common in Colombian school children. AN - WOS:000331539100023 AU - Saps, M. AU - Nichols-Vinueza, D. X. AU - Rosen, J. M. AU - Velasco-Benitez, C. A. DA - Mar DO - 10.1016/j.jpeds.2013.10.088 IS - 3 N1 - Saps, Miguel Nichols-Vinueza, Diana X. Rosen, John M. Alberto Velasco-Benitez, Carlos Rosen, John/ABH-1241-2020 Velasco-Benitez, Carlos A/0000-0001-5647-3024; Rosen, John/0000-0003-4291-3214; Velasco-Benitez, Carlos Alberto/0000-0002-4062-5326 1097-6833 PY - 2014 SN - 0022-3476 SP - 542-+ ST - Prevalence of Functional Gastrointestinal Disorders in Colombian School Children T2 - Journal of Pediatrics TI - Prevalence of Functional Gastrointestinal Disorders in Colombian School Children UR - ://WOS:000331539100023 VL - 164 ID - 2318 ER - TY - JOUR AB - OBJECTIVE: To determine the prevalence and impact of pediatric abdominal pain (AP). STUDY DESIGN: Prospective cohort study (12/2005-06/2006), with gastrointestinal and other symptoms assessed weekly. Anxiety, depression, functional disability, quality of life, somatization, coping, school absenteeism and medical care were assessed in 237 students in the third through eighth grades (11.8 years; 134 girls) from 2 public schools weekly. Complete data were obtained on 4606 of 5175 (89%) possible questionnaires. RESULTS: Seventy-two percent of children reported >1 somatic symptom weekly, and 45% of children reported >1 gastrointestinal symptom weekly. The weekly prevalence of AP was 38%, and 90% of children reported AP at least once. AP persisted >4 consecutive weeks in 52% of children and was associated with higher anxiety (P < .001) and depression (P < .001) scores and worse quality of life (P < .001). Twenty-three percent of children missed school for AP (average, 2.3 days), and 10% of parents of those children missed work (average, 1.9 days). Presence of AP (P < .001) was independently associated with school absences. Four children (2%) sought medical attention. CONCLUSIONS: AP is common in school-age children and is associated with worse quality of life, psychological co-morbidities, school absenteeism, and parental work absences. AU - Saps, Miguel AU - Seshadri, Roopa AU - Sztainberg, Marcelo AU - Schaffer, Gilda AU - Marshall, Beth M. AU - Di Lorenzo, Carlo DA - 2009/03// DO - 10.1016/j.jpeds.2008.09.047 DP - PubMed IS - 3 J2 - J Pediatr KW - Abdominal Pain Absenteeism Adaptation, Psychological Adolescent Anxiety Chicago Child Comorbidity Cost of Illness Depression Female Humans Male Parents Prevalence Prospective Studies Quality of Life Schools Students Surveys and Questionnaires LA - eng PY - 2009 SN - 1097-6833 SP - 322-326 ST - A prospective school-based study of abdominal pain and other common somatic complaints in children T2 - The Journal of Pediatrics TI - A prospective school-based study of abdominal pain and other common somatic complaints in children UR - http://www.ncbi.nlm.nih.gov/pubmed/19038403 VL - 154 ID - 115 ER - TY - JOUR AB - Introduction: Current knowledge on the prevalence of common gastrointestinal (GI) problems is based on office-based samples or retrospective questionnaires, leading to possible bias and inaccurate estimates. Aims: To examine the prevalence of GI symptoms in schoolage children. Importance: This is the first American prospective community study intended to assess the prevalence of common GI symptoms in children. Patients and Methods: All fourth- and fifth-grade students from a middle-size urban school were invited to participate in a prospective cohort pilot study by completing confidential weekly surveys. The survey included a set of 8 age-appropriate, validated questions assessing the presence and severity of abdominal pain, constipation, diarrhea, nausea, vomiting, chest pain, headaches and limb pain. Results: A total of 48 children (32 boys and 16 girls) participated in the study. Data were obtained for 16 weeks on 690 (90.5%) of 768 possible children per week. Children reported at least 1 symptom in 544 (70%) children per week. Headaches were the most common complaint (55% [range, 40%-72%] children per week). Sixty percent of children (range, 46%-89%) reported at least 1 GI symptom weekly. The overall prevalence of GI symptoms was the following: abdominal pain 46% (range, 28%-72%), nausea 28% (range, 17%-59%), constipation 18% (range, 7%-39%), diarrhea 17% (range, 11%-24%) and vomiting 5% (range, 0%-13%). None of the children missed school because of persistent GI symptoms during the study. Discussion: The investigation demonstrates the feasibility of prospective school studies in children. The high prevalence of GI symptoms not interfering with school attendance in children underscores the benign nature of such symptoms in most children. Conclusion: Gastrointestinal symptoms are common somatic complaints among school-age children. AN - WOS:000241004900011 AU - Saps, M. AU - Sztainberg, M. AU - Di Lorenzo, C. DA - Oct DO - 10.1097/01.mpg.0000235979.41947.f6 IS - 4 N1 - Saps, Miguel Sztainberg, Marcelo Di Lorenzo, Carlo 1536-4801 PY - 2006 SN - 0277-2116 SP - 477-482 ST - A prospective community-based study of gastroenterological symptoms in school-age children T2 - Journal of Pediatric Gastroenterology and Nutrition TI - A prospective community-based study of gastroenterological symptoms in school-age children UR - ://WOS:000241004900011 VL - 43 ID - 2718 ER - TY - JOUR AB - Objectives: The aim of the study was to establish the prevalence of abdominal pain (AP) in school children in Pasto (Colombia) and determine the effect of AP on their daily activities; and compare the prevalence of AP and other gastrointestinal symptoms between school children from Pasto and Chicago. Methods: Fourth-and fifth-grade students from a public school and a private school in Colombia were invited to participate in a prospective study using the same methods and questionnaires (Spanish version) as a previous study conducted in Chicago schools. Children completed weekly confidential surveys for 8 consecutive weeks. Results: A total of 332 children participated in the study (40% girls, mean age 9.97 years, median 10, range 8-12 years): public school (288), private school (44). A total of 2425 surveys were analyzed. Out of 2656 possible weekly surveys (332 children x 8 weeks), 91.3% were completed. Overall weekly prevalence of gastrointestinal symptoms: AP (39%), nausea (29.5%), constipation (14%), diarrhea (10.5%), vomiting (9%). Children with AP reported interference with activities: gym (21.9%), school (17.3%), difficulty sleeping (13.7%), and social activities (12.6%). Out of all children, 8.4% sought medical attention for AP during the study period. Conclusions: Gastrointestinal symptoms are common in school-aged children in Colombia and interfere with both daily activities and school attendance. The prevalence of AP, diarrhea, and vomiting found in the present study was similar to published prevalence of American children using similar methods. AN - WOS:000429814300018 AU - Saps, M. AU - Velasco-Benitez, C. A. AU - Blom, P. J. J. AU - Benninga, M. A. AU - Nichols-Vinueza, D. X. DA - Mar DO - 10.1097/mpg.0000000000001720 IS - 3 N1 - Saps, Miguel Velasco-Benitez, Carlos A. Blom, Puck J. J. Benninga, Marc A. Nichols-Vinueza, Diana X. Velasco-Benitez, Carlos Alberto/0000-0002-4062-5326 1536-4801 PY - 2018 SN - 0277-2116 SP - 391-394 ST - Prospective Study of Gastrointestinal Symptoms in School Children of South America T2 - Journal of Pediatric Gastroenterology and Nutrition TI - Prospective Study of Gastrointestinal Symptoms in School Children of South America UR - ://WOS:000429814300018 VL - 66 ID - 2027 ER - TY - JOUR AB - OBJECTIVES: To assess the prevalence of functional gastrointestinal disorders (FGIDs) in children using Rome IV criteria and to compare the prevalence of FGIDs using Rome IV with Rome III criteria. STUDY DESIGN: This was a cross-sectional study using the same methods as our previous study on FGIDs in Colombia. The Questionnaire of Pediatric Gastrointestinal Symptoms Rome IV version was translated into Spanish, followed by reverse translation. Terms were adjusted to children's language by using focus groups of children. School children aged 8-18 years completed the Spanish version of the Questionnaire of Pediatric Gastrointestinal Symptoms Rome IV. Data were compared with Rome III data. RESULTS: In total, there were 3567 children (from 6 cities): 1071 preadolescents (8-12 years) and 2496 adolescents (13-18 years). Average age 13.7 ± 2.4 years (56.5% girls). A total of 21.2% of children had at least 1 FGID. Prevalence was significantly lower than Rome III (P = .004). Similar to Rome III, disorders of defecation were the most common, followed by abdominal pain, and disorders of nausea and vomiting. Prevalence of abdominal migraine decreased (P = .000) and functional dyspepsia increased (P = .000). The new diagnoses functional vomiting and functional nausea were present in 0.7% of all children. CONCLUSIONS: The application of the Rome IV criteria resulted in a significantly lower prevalence of FGIDs; however, the relative frequency of each subgroup of disorders did not change. New diagnoses of the Rome IV criteria were present in a small percentage of children. AD - Division of Pediatric Gastroenterology, Hepatology & Nutrition, Department of Pediatrics, Miller School of Medicine, University of Miami, Miami, FL. Electronic address: msaps@med.miami.edu. Department of Pediatrics, Universidad del Valle de Cali, Cali, Colombia. Division of Pediatric Gastroenterology, Hepatology & Nutrition, Department of Pediatrics, Miller School of Medicine, University of Miami, Miami, FL. Hospital Regional María Inmaculada de Florencia, Caquetá, Colombia. AN - 29747935 AU - Saps, M. AU - Velasco-Benitez, C. A. AU - Langshaw, A. H. AU - Ramírez-Hernández, C. R. DA - Aug DO - 10.1016/j.jpeds.2018.03.037 DP - NLM ET - 2018/05/12 KW - Adolescent Child Colombia/epidemiology Cross-Sectional Studies Female Gastrointestinal Diseases/diagnosis/*epidemiology Humans Male Prevalence *Severity of Illness Index Translations *Rome IV *children *functional gastrointestinal disorders *school LA - eng N1 - 1097-6833 Saps, Miguel Velasco-Benitez, Carlos Alberto Langshaw, Amber Hamid Ramírez-Hernández, Carmen Rosy Comparative Study Journal Article Observational Study United States J Pediatr. 2018 Aug;199:212-216. doi: 10.1016/j.jpeds.2018.03.037. Epub 2018 May 7. PY - 2018 SN - 0022-3476 SP - 212-216 ST - Prevalence of Functional Gastrointestinal Disorders in Children and Adolescents: Comparison Between Rome III and Rome IV Criteria T2 - J Pediatr TI - Prevalence of Functional Gastrointestinal Disorders in Children and Adolescents: Comparison Between Rome III and Rome IV Criteria VL - 199 ID - 3821 ER - TY - JOUR AB - There have been a few studies regarding detail of back pain in adolescents with idiopathic scoliosis (IS) as prevalence, location, and severity. The condition of back pain in adolescents with IS was clarified based on a cross-sectional study using a questionnaire survey, targeting a total of 43,630 pupils, including all elementary school pupils from the fourth to sixth grade (21,893 pupils) and all junior high pupils from the first to third year (21,737 pupils) in Niigata City (population of 785,067), Japan. 32,134 pupils were determined to have valid responses (valid response rate: 73.7%). In Niigata City, pupils from the fourth grade of elementary school to the third year of junior high school are screened for scoliosis every year. This screening system involves a three-step survey, and the third step of the survey is an imaging and medical examination at the Niigata University Hospital. In this study, the pupils who answered in the questionnaire that they had been advised to visit Niigata University Hospital after the school screening were defined as Scoliosis group (51 pupils; 0.159%) and the others were defined as No scoliosis group (32,083 pupils). The point and lifetime prevalence of back pain, the duration, the recurrence, the severity and the location of back pain were compared between these groups. The severity of back pain was divided into three levels (level 1 no limitation in any activity; level 2 necessary to refrain from participating in sports and physical activities, and level 3 necessary to be absent from school). The point prevalence was 11.4% in No scoliosis group, and 27.5% in Scoliosis group. The lifetime prevalence was 32.9% in No scoliosis group, and 58.8% in Scoliosis group. According to the gender- and school-grade-adjusted odds ratios (OR), Scoliosis group showed a more than twofold elevated odds of back pain compared to No scoliosis group irrespective of the point or lifetime prevalence of back pain (OR, 2.29; P = 0.009 and OR, 2.10; P = 0.012, respectively). Scoliosis group experienced significantly more severe pain, and of a significantly longer duration with more frequent recurrences in comparison to No scoliosis group. Scoliosis group showed significantly more back pain in the upper and middle right back in comparison to No scoliosis group. These findings suggest that there is a relationship between pain around the right scapula in Scoliosis group and the right rib hump that is common in IS. AN - WOS:000286673300016 AU - Sato, T. AU - Hirano, T. AU - Ito, T. AU - Morita, O. AU - Kikuchi, R. AU - Endo, N. AU - Tanabe, N. DA - Feb DO - 10.1007/s00586-010-1657-6 IS - 2 N1 - Sato, Tsuyoshi Hirano, Toru Ito, Takui Morita, Osamu Kikuchi, Ren Endo, Naoto Tanabe, Naohito Ito, Takui/0000-0003-0686-8129 PY - 2011 SN - 0940-6719 SP - 274-279 ST - Back pain in adolescents with idiopathic scoliosis: epidemiological study for 43,630 pupils in Niigata City, Japan T2 - European Spine Journal TI - Back pain in adolescents with idiopathic scoliosis: epidemiological study for 43,630 pupils in Niigata City, Japan UR - ://WOS:000286673300016 VL - 20 ID - 2512 ER - TY - JOUR AB - A cross-sectional study targeted a total of 43,630 pupils in Niigata City, Japan was performed. The objective was to clarify the present incidence of low back pain (LBP) in childhood and adolescence in Japan. It has recently been recognized that LBP in childhood and adolescence is also as common a problem as that for adults and most of these studies have been conducted in Europe, however, none have so far been made in Japan. A questionnaire survey was conducted using 43,630 pupils, including all elementary school students from the fourth to sixth grade (21,893 pupils) and all junior high students from the first to third year (21,737 pupils) in Niigata City (population of 785,067) to examine the point prevalence of LBP, the lifetime prevalence, the gender differences, the age of first onset of LBP in third year of junior high school students, the duration, the presence of recurrent LBP or not, the trigger of LBP, and the influences of sports and physical activities. In addition, the severity of LBP was divided into three levels (level 1: no limitation in any activity; level 2: necessary to refrain from participating in sports and physical activities, and level 3: necessary to be absent from school) in order to examine the factors that contribute to severe LBP. The validity rate was 79.8% and the valid response rate was 98.8%. The point prevalence was 10.2% (52.3% male and 47.7% female) and the lifetime prevalence was 28.8% (48.5% male and 51.5% female). Both increased as the grade level increased and in third year of junior high school students, a point prevalence was seen in 15.2% while a lifetime prevalence was observed in 42.5%. About 90% of these students experienced first-time LBP during the first and third year of junior high school. Regarding the duration of LBP, 66.7% experienced it for less than 1 week, while 86.1% suffered from it for less than 1 month. The recurrence rate was 60.5%. Regarding the triggers of LBP, 23.7% of them reported the influence of sports and exercise such as club activities and physical education, 13.5% reported trauma, while 55.6% reported no specific triggers associated with their LBP. The severity of LBP included 81.9% at level 1, 13.9% at level 2 and 4.2% at level 3. It was revealed that LBP in childhood and adolescence is also a common complaint in Japan, and these findings are similar to previous studies conducted in Europe. LBP increased as the grade level increased and it appeared that the point and lifetime prevalence in adolescence are close to the same levels as those seen in the adulthood and there was a tendency to have more severe LBP in both cases who experienced pain for more than 1 month and those with recurrent LBP. AD - Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan. tsuyoshis1@mac.com AN - 18830637 AU - Sato, T. AU - Ito, T. AU - Hirano, T. AU - Morita, O. AU - Kikuchi, R. AU - Endo, N. AU - Tanabe, N. C2 - PMC2583196 DA - Nov DO - 10.1007/s00586-008-0788-5 DP - NLM ET - 2008/10/03 IS - 11 KW - Activities of Daily Living Adolescent Age Distribution Age of Onset Aging/*physiology Athletic Injuries/*epidemiology Child Chronic Disease/epidemiology Comorbidity Cross-Sectional Studies Disability Evaluation Female Humans Incidence Japan/epidemiology Low Back Pain/*epidemiology Male Physical Fitness/physiology Prevalence Recurrence Severity of Illness Index Sex Distribution LA - eng N1 - 1432-0932 Sato, Tsuyoshi Ito, Takui Hirano, Toru Morita, Osamu Kikuchi, Ren Endo, Naoto Tanabe, Naohito Journal Article Eur Spine J. 2008 Nov;17(11):1441-7. doi: 10.1007/s00586-008-0788-5. Epub 2008 Oct 1. PY - 2008 SN - 0940-6719 (Print) 0940-6719 SP - 1441-7 ST - Low back pain in childhood and adolescence: a cross-sectional study in Niigata City T2 - Eur Spine J TI - Low back pain in childhood and adolescence: a cross-sectional study in Niigata City VL - 17 ID - 3377 ER - TY - JOUR AB - BACKGROUND: Multisomatoform disorder is characterised by severe and disabling bodily symptoms, and pain is one of the most common and impairing of these. Furthermore, these bodily symptoms cannot be explained by an underlying organic disorder. Patients with multisomatoform disorder are commonly found at all levels of healthcare and are typically difficult to treat for physicians as well as for mental health specialists. AIMS: To test whether brief psychodynamic interpersonal therapy (PIT) effectively improves the physical quality of life in patients who have had multisomatoform disorder for at least 2 years. METHOD: We recruited 211 patients (from six German academic outpatient centres) who met the criteria for multisomatoform disorder for a randomised, controlled, 12-week, parallelgroup trial from 1 July 2006 to 1 January 2009 (International Standard Randomised Controlled Trial Number ISRCTN23215121). We randomly assigned the patients to receive either 12 weekly sessions of PIT (n = 107) or three sessions of enhanced medical care (EMC, n = 104). The physical component summary of the Short Form Health Survey (SF-36) was the pre-specified primary outcome at a 9-month follow-up. RESULTS: Psychodynamic interpersonal therapy improved patients' physical quality of life at follow-up better than EMC (mean improvement in SF-36 score: PIT 5.3, EMC 2.2), with a small to medium between-group effect size (d = 0.42, 95% CI 0.15-0.69, P = 0.001). We also observed a significant improvement in somatisation but not in depression, health anxiety or healthcare utilisation. CONCLUSIONS: This trial documents the long-term efficacy of brief PIT for improving the physical quality of life in patients with multiple, difficult-to-treat, medically unexplained symptoms. AD - Department of Psychosomatic Medicine and Psychotherapy, Klinikum rechts der Isar, Technische Universität München, Germany. AN - 22075651 AU - Sattel, H. AU - Lahmann, C. AU - Gündel, H. AU - Guthrie, E. AU - Kruse, J. AU - Noll-Hussong, M. AU - Ohmann, C. AU - Ronel, J. AU - Sack, M. AU - Sauer, N. AU - Schneider, G. AU - Henningsen, P. DA - Jan DO - 10.1192/bjp.bp.111.093526 DP - NLM ET - 2011/11/15 IS - 1 KW - Adolescent Adult Aged Antidepressive Agents/therapeutic use Anxiety Attitude to Health Depressive Disorder, Major/psychology/therapy Germany Humans Middle Aged Outcome Assessment, Health Care/*statistics & numerical data Pain/etiology/*psychology Pain Management/*methods Primary Health Care/*statistics & numerical data Psychotherapy, Brief/*methods Quality of Life Severity of Illness Index Somatoform Disorders/psychology/*therapy Young Adult LA - eng N1 - 1472-1465 Sattel, H Lahmann, C Gündel, H Guthrie, E Kruse, J Noll-Hussong, M Ohmann, C Ronel, J Sack, M Sauer, N Schneider, G Henningsen, P Journal Article Multicenter Study Randomized Controlled Trial Research Support, Non-U.S. Gov't England Br J Psychiatry. 2012 Jan;200(1):60-7. doi: 10.1192/bjp.bp.111.093526. Epub 2011 Nov 10. PY - 2012 SN - 0007-1250 SP - 60-7 ST - Brief psychodynamic interpersonal psychotherapy for patients with multisomatoform disorder: randomised controlled trial T2 - Br J Psychiatry TI - Brief psychodynamic interpersonal psychotherapy for patients with multisomatoform disorder: randomised controlled trial VL - 200 ID - 3743 ER - TY - JOUR AB - Background Having atopic dermatitis (AD) as well as other chronic diseases is often associated with reduced mental health. Adolescents with AD are thought to be especially vulnerable, but few studies have included an ample number of young people. Objectives To study self-reported mental distress among boys and girls 13-19 years of age with AD compared with mental distress among healthy adolescents as well as mental distress among adolescents with other chronic diseases or complaints, such as headache, neck or shoulder pain, asthma, allergy and rhinitis. Methods The Young-HUNT study was conducted as a cross-sectional, population-based survey in 1995-97. All students in Nord-Trondelag County, Norway, aged 13-19 years were invited, and some 89% participated. A questionnaire on mental and somatic health, life-style and social conditions was completed during one school hour. Results A total of 4384 girls and 4433 boys participated. The prevalence of mental distress was higher among older teenagers, and more than every fourth girl aged 17-19 reported mental distress. Although more girls than boys reported mental distress, AD, headache and neck or shoulder pain, the odds for reporting both AD and mental distress were higher for boys [odds ratio (OR) = 2.1 (1.6-2.9)] compared with girls [OR = 1.3 (1.1-1.6)]. A corresponding sex difference in reporting mental distress was also seen for some other chronic diseases or complaints. Conclusions In adolescents aged 13-19 years there was a strong and significant association between self-reported mental distress and AD as well as headache and neck or shoulder pain for both sexes. Although boys reported fewer complaints as AD, they perceived the complaints a heavier burden than did the girls. AN - WOS:000243683100010 AU - Saunes, M. AU - Smidesang, I. AU - Holmen, T. L. AU - Johnsen, R. DA - Feb DO - 10.1111/j.1365-2133.2006.07688.x IS - 2 N1 - Saunes, M. Smidesang, I. Holmen, T. L. Johnsen, R. 1365-2133 PY - 2007 SN - 0007-0963 SP - 283-288 ST - Atopic dermatitis in adolescent boys is associated with greater psychological morbidity compared with girls of the same age: the Young-HUNT study T2 - British Journal of Dermatology TI - Atopic dermatitis in adolescent boys is associated with greater psychological morbidity compared with girls of the same age: the Young-HUNT study UR - ://WOS:000243683100010 VL - 156 ID - 2699 ER - TY - JOUR AB - BACKGROUND: The spine is the most common site of skeletal metastatic disease. Vertebral body metastases (VBM) can cause crippling pain, fractures, and spinal cord compression. Radiofrequency ablation (RFA) is a minimally invasive technique that has proven to be a safe method of targeted tissue destruction. Studies have shown that RFA combined with cement vertebral augmentation is safe and effective and has been associated with significant improvements in pain and quality of life. OBJECTIVES: The purpose of this study was continued evaluation of the safety and efficacy of this technique. STUDY DESIGN: Prospective cohort. SETTING: A single academic medical center. METHODS: Patients undergoing RFA with cement vertebral augmentation for a painful thoracic or lumbar VBM were eligible for inclusion. Additional inclusion criteria included pain concordant with a metastatic lesion on cross-sectional imaging, aged 18 years or older, and considered candidates for spinal tumor ablation by the operating physician. Patients with vertebral metastatic disease in the cervical spine or patients with spinal cord compression from posterior tumor extension were excluded. Ablation within each VBM was performed using a bipolar radiofrequency probe with an extensible electrode and available articulation, permitting vertebral body navigation percutaneously. Patients were evaluated at baseline, 3 days, one week, one month, and 3 months using the Numeric Rating Scale (NRS-11) and Functional Assessment of Cancer Therapy-General 7 (FACT-G7) to assess pain and quality-of-life, respectively. A one-sample t test was performed, and 95% confidence intervals were calculated to assess changes in average NRS-11 and FACT-G7 scores. RESULTS: A total of 30 patients met inclusion criteria and underwent RFA of one or more VBM. Patients with 13 different primary cancers types underwent treatment. Patients received RFA to either one (n = 26; 87%) or 2 vertebral body levels (n = 4; 13%). Of the 34 levels, 13 were thoracic vertebra (38%) and 21 were lumbar vertebra (62%). Average NRS-11 scores decreased from a baseline of 5.77 to 4.65 (3 days; P = 0.16), 3.33 (one week; P < 0.01), 2.64 (one month; P < 0.01), and 2.61 (3 months; P < 0.01). FACT-G7 increased from a baseline average of 13.0 to 14.7 (3 days; P = 0.13), 14.69 (one week; P = 0.15), 14.04 (one month; P = 0.35), and 15.11 (3 months; P = 0.07). No major adverse events were reported. LIMITATIONS: A heterogeneous patient population, small sample size, and potential confounders of concurrent variable adjuvant therapies were limitations. Additionally, most patients received both cement augmentation and targeted RFA, making it difficult to distinguish independent analgesic benefits of the therapies. CONCLUSIONS: This study demonstrates that minimally invasive targeted RFA with cement augmentation of spinal metastatic lesions is an effective treatment for patients with VBM. KEY WORDS: Cancer, cancer pain, spinal metastasis, radiofrequency ablation, tumor ablation, cement augmentation. AD - University of Kansas Medical Center, Kansas City, KS. Department of Anesthesiology, University of Kansas Medical Center, Kansas City, KS. AN - 31561656 AU - Sayed, D. AU - Jacobs, D. AU - Sowder, T. AU - Haines, D. AU - Orr, W. DA - Sep DP - NLM ET - 2019/09/29 IS - 5 KW - Adolescent Adult Aged Bone Cements/*therapeutic use Cancer Pain Catheter Ablation/*methods Combined Modality Therapy Female Humans Lumbar Vertebrae/surgery Male Middle Aged Pain/surgery Pain Measurement Prospective Studies Quality of Life Radio Waves Spinal Neoplasms/*radiotherapy Thoracic Vertebrae/surgery Treatment Outcome LA - eng N1 - 2150-1149 Sayed, Dawood Jacobs, Daniel Sowder, Timothy Haines, Daniel Orr, Walter Journal Article Research Support, Non-U.S. Gov't United States Pain Physician. 2019 Sep;22(5):E441-E449. PY - 2019 SN - 1533-3159 SP - E441-e449 ST - Spinal Radiofrequency Ablation Combined with Cement Augmentation for Painful Spinal Vertebral Metastasis: A Single-Center Prospective Study T2 - Pain Physician TI - Spinal Radiofrequency Ablation Combined with Cement Augmentation for Painful Spinal Vertebral Metastasis: A Single-Center Prospective Study VL - 22 ID - 3740 ER - TY - JOUR AB - BACKGROUND & AIMS: Little is known about the prevalence of functional gastrointestinal disorders (FGIDs) in children from the Mediterranean area of Europe. We aimed to assess the prevalence of FGIDs in children and adolescents in this region. METHODS: We collected data on 13,750 children (4-18 years old) enrolled in the Mediterranean-European Area Project, a school-based health study performed in Croatia, Greece, Israel, Italy, Jordan, Lebanon, Macedonia, Serbia, and Spain. Data were collected from March to June and in September of 2016. We analyzed data from 6602 students 4 to 10 years old (group A; mean age, 7.7 ± 1.9 y), and 7148 subjects 11 to 18 years old (group B; mean age, 13.8 ± 2.1 y). Children with FGIDs were identified based on answers to questionnaires on pediatric gastrointestinal symptoms, selected based on Rome III criteria. RESULTS: In group A, the prevalence of FGIDs was 20.7%. The most frequent disorders were functional constipation (11.7%), irritable bowel syndrome (IBS, 4%), aerophagia (3.5%), and abdominal migraine (3.1%). The prevalence of abdominal migraine was significantly higher in girls than in boys (P = .007). In group B, the overall prevalence of FGIDs was 26.6%. The most frequent disorders were functional constipation (13.1%), abdominal migraine (7.8%), aerophagia (6.3%), and IBS (5.6%). In group B, FGIDs had a higher prevalence among girls than boys (P < .001). In both groups, we found significant differences in the prevalence of specific disorders among specific countries. CONCLUSIONS: In an analysis of data on children 4 to 18 years old from the Mediterranean-European Area Project, we found FGIDs to be more frequent in girls. Functional constipation, aerophagia, abdominal migraine, and IBS are the most common disorders. However, the prevalence of FGIDs varies significantly among countries. AD - Section of Paediatrics, Department of Translational Medical Sciences, University "Federico II," Naples, Italy. Referral Centre for Paediatric Gastroenterology and Nutrition, "University Children's Hospital," Zagreb, Croatia. Department of Paediatrics, Institute for Child and Youth Health Care of Vojvodina, Medical Faculty Novi Sad, Novi Sad, Serbia. Department of Paediatric Gastroenterology, University Hospital Osijek, Osijek, Croatia. Department of Paediatrics, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain. University Children Hospital, Faculty of Medicine, Skopje, Macedonia. Pediatric Department, Jordan University of Science and Technology, Irbid, Jordan. First Department of Paediatrics, University of Athens, Athens Children's Hospital "Agia Sophia," Athens, Greece. Nutrition and Dietetics Department, School of Food Technology and Nutrition, Technological Education Institute, Thessaloniki, Greece. Institute of Gastroenterology, Nutrition and Liver Diseases, Sackler Faculty of Medicine, Tel Aviv University, "Schneider Children's Medical Center of Israel," Petach Tikva, Israel. Makassed University General Hospital, Beirut, Lebanon. Department of Public Health, University "Federico II," Naples, Italy. Pediatric Gastroenterology, Hepatology and Nutrition Unit, Hospital Clìnico Universitario de Santiago, Santiago de Compostela, Spain. Section of Paediatrics, Department of Translational Medical Sciences, University "Federico II," Naples, Italy. Electronic address: staiano@unina.it. AN - 29129667 AU - Scarpato, E. AU - Kolacek, S. AU - Jojkic-Pavkov, D. AU - Konjik, V. AU - Živković, N. AU - Roman, E. AU - Kostovski, A. AU - Zdraveska, N. AU - Altamimi, E. AU - Papadopoulou, A. AU - Karagiozoglou-Lampoudi, T. AU - Shamir, R. AU - Bar Lev, M. R. AU - Koleilat, A. AU - Mneimneh, S. AU - Bruzzese, D. AU - Leis, R. AU - Staiano, A. DA - Jun DO - 10.1016/j.cgh.2017.11.005 DP - NLM ET - 2017/11/14 IS - 6 KW - Adolescent Child Child, Preschool Europe/epidemiology Female Gastrointestinal Diseases/*epidemiology Humans Male Mediterranean Region/epidemiology Prevalence Prospective Studies Risk Factors Sex Factors *Abdominal Pain *Epidemiology *meap *Survey LA - eng N1 - 1542-7714 Scarpato, Elena Kolacek, Sanja Jojkic-Pavkov, Danijela Konjik, Vlatka Živković, Nataša Roman, Enriqueta Kostovski, Aco Zdraveska, Nikolina Altamimi, Eyad Papadopoulou, Alexandra Karagiozoglou-Lampoudi, Thomai Shamir, Raanan Bar Lev, Michal Rozenfeld Koleilat, Aziz Mneimneh, Sirin Bruzzese, Dario Leis, Rosaura Staiano, Annamaria MEAP Group Journal Article Multicenter Study Research Support, Non-U.S. Gov't United States Clin Gastroenterol Hepatol. 2018 Jun;16(6):870-876. doi: 10.1016/j.cgh.2017.11.005. Epub 2017 Nov 9. PY - 2018 SN - 1542-3565 SP - 870-876 ST - Prevalence of Functional Gastrointestinal Disorders in Children and Adolescents in the Mediterranean Region of Europe T2 - Clin Gastroenterol Hepatol TI - Prevalence of Functional Gastrointestinal Disorders in Children and Adolescents in the Mediterranean Region of Europe VL - 16 ID - 3741 ER - TY - JOUR AB - Oral and dental health are integral parts of good overall health, and dental caries is the most common chronic infectious disease of childhood. A child with severe dental caries may experience chronic oral pain and infection, be malnourished, frequently absent from school, and suffer from low self-esteem because of missing or defective teeth. Evidence in the dental literature increasingly suggests that, to be successful in preventing dental disease, clinicians must begin risk-factor determination, preventive counseling, and preventive interventions within the first year of life (infant oral health care is discussed in detail in the article by Nowak and Warren later in this issue). Pediatricians are well positioned to begin this process as they see their patients for well-baby visits and as they provide anticipatory guidance to parents and other caregivers. Pediatricians are also in a good position to see that every child has a dental home in addition to the medical home. This article provides information to pediatricians that will enable them to provide practical, targeted, and effective advice to parents about preventing dental disease. A full review of the pathogenesis of dental caries can be found in the article by Caufield and Griffen earlier in this issue. This article focuses on reviews of etiologic factors, the evidence to support preventive measures for each factor, and recommendations that can be made to parents. Risk factors for dental disease are presented to enable pediatricians to identify infants and toddlers at high risk for caries. The role of fluoride in caries prevention is discussed, with emphasis on dietary fluoride supplements, which are often prescribed by pediatricians. Finally this information is brought together in a section on anticipatory guidance and other interventions that enable pediatricians to begin the process of dental disease prevention before referral for an initial dental evaluation. As explained elsewhere in this issue, transmission of the bacterial etiologic agent for caries, mutans streptococci (MS), occurs in infancy. Thus, true prevention can occur only in infants who have not yet been infected. When the transmission of MS has occurred, pediatricians and dentists must consider ways to suppress the caries activity through the medical management of dental caries.(15) Medical, or nonsurgical, management can be used up to and including the point at which tooth caviation occurs. As illustrated in Table 1, surgical management (i.e., excavation and replacement of carious tooth structure) must be used at some point to deal with the symptoms of dental caries, that is, cavities.(14) This schema also indicates that treatment becomes mole expensive as it becomes more invasive. Prevention and early diagnosis are just as important in managing dental caries as in managing any disease. AN - WOS:000089957300004 AU - Schafer, T. E. AU - Adair, S. M. DA - Oct DO - 10.1016/s0031-3955(05)70256-x IS - 5 N1 - Schafer, TE Adair, SM Schafer, Tara E/J-2273-2018 Schafer, Tara E/0000-0002-8205-2095 1557-8240 PY - 2000 SN - 0031-3955 SP - 1021-+ ST - Prevention of dental disease - The role of the pediatrician T2 - Pediatric Clinics of North America TI - Prevention of dental disease - The role of the pediatrician UR - ://WOS:000089957300004 VL - 47 ID - 2864 ER - TY - JOUR AB - Caring for patients with congenital pelvic anomalies can be challenging in many ways but one crucial aspect is providing longitudinal into adulthood. Newborns with urinary, intestinal or vaginal obstruction require urgent operations to relieve obstruction followed by multiple reconstructive procedures involving the perineum. Openings are created in the pelvic floor musculature that did not exist in development. Adolescence presents further challenges for these postoperative patients while other diagnoses present for the first time in the peri-pubertal teenage years. Young adults can have new symptoms when they become sexually active and are faced with reproductive decisions. During all of these time periods, optimization of function is of paramount importance and patients who are suffering are not able to participate in school, sports or work. This study evaluates the prevalence of pelvic pain in newborns and adolescents with complex congenital pelvic anomalies, associated factors and possible treatment options. AD - Division of Pediatric Surgery, Phoenix Children's Hospital, 1919 E. Thomas Rd., Phoenix, AZ 85016, United States. Division of Pediatric and Adolescent Gynecology, Phoenix Children's Hospital, Phoenix, AZ, United States. Mount Holyoke College, South Hadley, MA, United States. Division of Pediatric Surgery, Phoenix Children's Hospital, 1919 E. Thomas Rd., Phoenix, AZ 85016, United States. Electronic address: ebaimbridge@phoenixchildrens.com. AN - 31668297 AU - Schall, K. AU - Parks, M. AU - Nemivant, S. AU - Hernandez, J. AU - Weidler, E. M. C2 - PMC6936264 C6 - NIHMS1544298 DA - Oct DO - 10.1016/j.sempedsurg.2019.150842 DP - NLM ET - 2019/11/02 IS - 5 KW - 46, XX Disorders of Sex Development/*epidemiology Adolescent Arizona/epidemiology Chronic Pain/epidemiology/etiology Cloaca/*abnormalities Congenital Abnormalities/*epidemiology Depression/etiology Female Humans Kidney/*abnormalities Mullerian Ducts/*abnormalities Pelvic Pain/epidemiology/*etiology Retrospective Studies Vagina/*abnormalities Young Adult Cloaca Cloacal anomalies Mrkh Mayer–Rokitansky–Kuster–Hauser syndrome Ohvira Obstructed hemivagina ipsilateral renal anomaly syndrome Pelvic pain LA - eng N1 - 1532-9453 Schall, Kathy Parks, Melissa Nemivant, Samantha Hernandez, Janett Weidler, Erica M R01 HD093450/HD/NICHD NIH HHS/United States Journal Article Semin Pediatr Surg. 2019 Oct;28(5):150842. doi: 10.1016/j.sempedsurg.2019.150842. Epub 2019 Sep 13. PY - 2019 SN - 1055-8586 (Print) 1055-8586 SP - 150842 ST - Pelvic pain in patients with complex mullerian anomalies including Mayer-Rokitansky-Kuster-Hauser syndrome (MRKH), obstructed hemi-vagina ipsilateral renal anomaly (OHVIRA), and complex cloaca T2 - Semin Pediatr Surg TI - Pelvic pain in patients with complex mullerian anomalies including Mayer-Rokitansky-Kuster-Hauser syndrome (MRKH), obstructed hemi-vagina ipsilateral renal anomaly (OHVIRA), and complex cloaca VL - 28 ID - 3591 ER - TY - JOUR AB - At least four percent of children have recurrent headaches and migraine is the most frequent cause. Migraine and tension-type headaches may co-exist. A variety of factors, specifically dietary and stressors (at home and at school) have been recognized as triggers. We have reviewed the role of the Neurosciences Nurse Clinician in the management of children with recurrent headaches in our Pediatric Neurology Outpatient Clinic. About 150 children with headache are seen in our clinic annually. The Nurse Clinician complements the Pediatric Neurologist's role in the following ways: 1) Provides educational material and reinforces the benign nature of the headache (i.e. absence of serious cause); 2) Discusses potential role for triggers; 3) Provides and emphasizes the importance of keeping a headache diary: teaches children and caregivers how triggers may be identified; 4) Makes follow-up telephone calls to determine changes in headache frequency/ severity. This approach minimizes the need for prophylactic medication (less than 25% of children we see require such treatment) and reduces the number of follow-up visits to Pediatric Neurologist and other physicians, thus minimizing health care costs. AN - 7626436 AU - Scham, I. DA - Jun DP - NLM ET - 1995/06/01 IS - 4 KW - Adolescent Child Child, Preschool Female Headache/*diagnosis/etiology/*therapy Humans Male *Nurse Clinicians Patient Education as Topic Recurrence LA - eng N1 - Scham, I Journal Article Canada Axone. 1995 Jun;16(4):83-6. PY - 1995 SN - 0834-7824 (Print) 0834-7824 SP - 83-6 ST - The role of the nurse clinician in recurrent childhood headache T2 - Axone TI - The role of the nurse clinician in recurrent childhood headache VL - 16 ID - 3379 ER - TY - JOUR AB - Background: Chronic abdominal pain (CAP) in children may be caused by entrapment of cutaneous branches of intercostal nerves (anterior cutaneous nerve entrapment syndrome, or ACNES). Local injection of anesthetics may offer relief, but pain is persistent in some children. This study is the first to describe the results of a 'cutaneous neurectomy' in children with refractory ACNES. Methods: Chronic abdominal pain children with suspected ACNES refractory to conservative treatment received a cutaneous neurectomy in a day care setting. They were interviewed postoperatively using an adapted quality of life questionnaire (testing quality of life in children). Results: All subjects (n = 6; median age, 15 years; range, 9-16 years) were previously healthy school-aged children without prior illness or earlier surgery. Each presented with intense abdominal pain and a positive Carnett sign. Blood, urine tests, and abdominal ultrasound investigations were normal. Delay in seeing a physician was 16 weeks, and school absence was 25 days. Before surgery, quality of life (pain, daily activities, and sports) was greatly diminished. After the neurectomy, all children were free of pain and had resumed their normal daily routine (follow-up at 6 months). Conclusions: The role of the abdominal wall as the source of childhood CAP is underestimated. Some children with CAP have ACNES. Children with refractory ACNES should be offered a cutaneous neurectomy, as this simple technique is effective in the short and long term. (C) 2011 Elsevier Inc. All rights reserved. AN - WOS:000289466100023 AU - Scheltinga, M. R. AU - Boelens, O. B. AU - Ten, Weta AU - Roumen, R. M. DA - Apr DO - 10.1016/j.jpedsurg.2010.08.054 IS - 4 N1 - Scheltinga, Marc R. Boelens, Oliver B. Ten, Walther E. Tjon A. Roumen, Rudi M. 1531-5037 PY - 2011 SN - 0022-3468 SP - 699-703 ST - Surgery for refractory anterior cutaneous nerve entrapment syndrome (ACNES) in children T2 - Journal of Pediatric Surgery TI - Surgery for refractory anterior cutaneous nerve entrapment syndrome (ACNES) in children UR - ://WOS:000289466100023 VL - 46 ID - 2501 ER - TY - CHAP AB - Pain assessment is of high priority in the clinical setting. Facial Pain Scales (FPSs) are pain assessment tools generally used with school-aged children. The implicit theoretical bases for the success of FPSs have seldom been explored. Explanations why and how FPSs work (or do not work) have not been addressed. We support the existence of a universal pain expression - the Primal Face of Pain (PFP), which is present at birth, evolved in nature, and modulated through sociocultural factors. We propose it to be key in understanding the applicability of FPSs. We present here the design of a computer-assisted descriptive study that will observe, quantify and model the PFP as present in newborns. Measurement of the PFP will lead to exploration of the theoretical consequences of its existence, particularly as related to pediatric pain assessment and the valid use of FPSs. Further, this work can lay a foundation for the development of a new generation of FPSs. AN - WOS:000253467002257 AU - Schiavenato, M. AU - Byers, J. AU - Scovanner, P. AU - Windyga, P. AU - Shah, M. AU - Ieee DO - 10.1109/iembs.2007.4353100 N1 - Schiavenato, Martin Byers, Jacqueline Scovanner, Paul Windyga, Piotr Shah, Mubarak 29th Annual International Conference of the IEEE-Engineering-in-Medicine-and-Biology-Society Aug 22-26, 2007 Lyon, FRANCE IEEE Engn Med & Biol Soc 1094-687x PY - 2007 SN - 978-1-4244-0787-3 SP - 3559-+ ST - Is there a primal face of pain? A methodology answer T2 - 2007 Annual International Conference of the Ieee Engineering in Medicine and Biology Society, Vols 1-16 T3 - Proceedings of Annual International Conference of the Ieee Engineering in Medicine and Biology Society TI - Is there a primal face of pain? A methodology answer UR - ://WOS:000253467002257 ID - 2704 ER - TY - JOUR AB - Background The increase in food intolerances poses a burgeoning problem in our society. Food intolerances not only lead to physical impairment of the individual patient but also result in a high socio-economic burden due to factors such as the treatment required as well as absenteeism. The present study aimed to explore whether lactose intolerant (LI) patients exhibit more frequent comorbidities than non-LI patients. Methods The study was conducted on a case-control basis and the results were determined using routine data analysis. Routine data from the IMS Disease Analyzer database were used for this purpose. A total of 6,758 data records were processed and analyzed. Results Th ere were significant correlations between LI and the incidence of osteoporosis, changes in mental status, and the presence of additional food intolerances. Comparing 3,379 LI vs. 3,379 non-LI patients, 34.5% vs. 17.7% (P < 0.0001) suffered from abdominal pain; 30.6% vs. 17.2% (P < 0.0001) from gastrointestinal infections; and 20.9% vs. 16.0% (P = 0.0053) from depression. Adjusted odds ratios (OR) were the highest for fructose intolerance (n = 229 LI vs. n = 7 non-LI; OR 31.06; P < 0.0001), irritable bowel syndrome (n = 247 LI vs. n = 44 non-LI; OR 5.23; P < 0.0001), and bloating (n = 351 LI vs. n = 68 non-LI; OR 4.94; P < 0.0001). Conclusion The study confirms that LI should not be regarded as an isolated illness but considered a possible trigger for further diseases. Additional research is necessary to assert more precise statements. AN - WOS:000378933700010 AU - Schiffner, R. AU - Kostev, K. AU - Gothe, H. DO - 10.20524/aog.2016.0009 IS - 2 N1 - Schiffner, Rebecca Kostev, Karel Gothe, Holger Kostev, Karel/S-4755-2019 Kostev, Karel/0000-0002-2124-7227 1792-7463 PY - 2016 SN - 1108-7471 SP - 174-179 ST - Do patients with lactose intolerance exhibit more frequent comorbidities than patients without lactose intolerance? An analysis of routine data from German medical practices T2 - Annals of Gastroenterology TI - Do patients with lactose intolerance exhibit more frequent comorbidities than patients without lactose intolerance? An analysis of routine data from German medical practices UR - ://WOS:000378933700010 VL - 29 ID - 2197 ER - TY - JOUR AB - Although myofascial pain has often been described as being associated with psychosocial stress, detailed evidence in support of this assumption, either from standardized clinical examination or from validated chronic stress questionnaires, is absent. The hypothesis of the present study was that some stressors lead to higher scores in patients suffering from chronic myofascial pain than in pain-free controls and in patients suffering from chronic facial pain. One hundred and fifty subjects were included in the study, and depending on clinical findings, divided into three groups: exclusively chronic myofascial pain group, controls with chronic facial pain but without temporomandibular disorders (TMD), and controls without pain or TMD. Chronic stress was assessed on nine subscales by use of a validated questionnaire. Myofascial pain patients have a significantly higher stress score for "social isolation" than pain-free controls (t-test, p = 0.003). However, they do not have higher scores than patients suffering from facial pain (t test, p = 0.169). Thus, the hypothesis of this study could not be completely rejected. AD - Department of Prosthodontics, University of Heidelberg, Heidelberg, Germany, Marc_Schmitter@med.uni-heidelberg.de. AN - 19705168 AU - Schmitter, M. AU - Keller, L. AU - Giannakopoulos, N. AU - Rammelsberg, P. DA - Oct DO - 10.1007/s00784-009-0330-0 DP - NLM ET - 2009/08/26 IS - 5 KW - Absenteeism Activities of Daily Living Adolescent Adult Aged Anxiety/psychology Chronic Disease Facial Pain/psychology Female Humans Job Satisfaction Male Middle Aged Pain Measurement Sex Factors Social Environment Social Isolation Stress, Psychological/*psychology Temporomandibular Joint Dysfunction Syndrome/*psychology Time Factors Workload Young Adult LA - eng N1 - 1436-3771 Schmitter, Marc Keller, Livia Giannakopoulos, Nikolaos Rammelsberg, Peter Comparative Study Journal Article Germany Clin Oral Investig. 2010 Oct;14(5):593-7. doi: 10.1007/s00784-009-0330-0. Epub 2009 Aug 25. PY - 2010 SN - 1432-6981 SP - 593-7 ST - Chronic stress in myofascial pain patients T2 - Clin Oral Investig TI - Chronic stress in myofascial pain patients VL - 14 ID - 3147 ER - TY - JOUR AB - Background: The use of the natural product, kratom, has increased significantly in recent years. The active compounds in kratom have been shown to produce both opioid and stimulant-like effects. While kratom is marketed as a safe, non-addictive method to treat pain and opioid withdrawal, there have been reports demonstrating that kratom is physiologically addictive and linked to overdose deaths. A limited number of case-reports are available describing treatment of kratom use disorder in middle-aged adults, generally in the context of chronic pain and in inpatient settings. Our case is unique in that we describe outpatient treatment of kratom use disorder in a young adult with comorbid attention deficit hyperactivity disorder (ADHD) and in the absence of chronic pain. Case: A 20-year-old college student with ADHD presented to an office-based opioid agonist treatment clinic (OBOT) for treatment of kratom use disorder. He was unable to attend inpatient or residential substance use treatment due to work and school obligations. Additionally, he had stopped taking his prescribed stimulant due to cardiac side effects. The OBOT team successfully initiated buprenorphine-naloxone (BUP/NAL) sublingual films via home induction to treat his kratom use disorder. The patient is being monitored monthly with plans to slowly taper his BUP/NAL dose as tolerated. Discussion: We present a case of a young adult male with kratom use disorder, complicated by a diagnosis of ADHD, successfully treated with BUP/NAL via home induction. The patient is currently kratom-free, reports improved mood and sleep patterns since initiating BUP/NAL, and is able to once again tolerate his ADHD stimulant medication. Healthcare providers should be aware of the use of kratom and consider utilizing BUP/NAL to treat dependence to this botanical drug. AN - WOS:000491985700001 AU - Schmuhl, K. K. AU - Gardner, S. M. AU - Cottrill, C. B. AU - Bonny, A. E. DA - Jul DO - 10.1080/08897077.2019.1671945 IS - 3 N1 - Schmuhl, Kelsey K. Gardner, Spencer M. Cottrill, Casey B. Bonny, Andrea E. Bonny, Andrea/0000-0001-5874-1942; Cottrill, Casey/0000-0002-8126-4950 1547-0164 PY - 2020 SN - 0889-7077 SP - 311-314 ST - Home induction and outpatient treatment of kratom use disorder with buprenorphine-naloxone: A case report in a young adult T2 - Substance Abuse TI - Home induction and outpatient treatment of kratom use disorder with buprenorphine-naloxone: A case report in a young adult UR - ://WOS:000491985700001 VL - 41 ID - 1875 ER - TY - JOUR AB - OBJECTIVES: The Pain Catastrophizing Scale-Child version (PCS-C) allows to identify children who are prone to catastrophic thinking. We aimed to adapt the Brazilian version of PCS-C (BPCS-C) to examine scale psychometric properties and factorial structure in children with and without chronic pain. Also, we assessed its correlation with salivary levels of Brain-Derived Neurotrophic factor (BDNF). METHODS: The Brazilian version of PCS-C was modified to adjust it for 7-12 years old children. To assess psychometric properties, 100 children (44 with chronic pain from a tertiary hospital and 56 healthy children from a public school) answered the BPCS-C, the visual analogue pain scale, and questions about pain interference in daily activities. We also collected a salivary sample to measure BDNF. RESULTS: We observed good internal consistency (Cronbach's value = 0.81). Parallel analysis retained 2 factors. Confirmatory factor analysis of our 2-factor model revealed consistent goodness-of-fit (IFI = 0.946) when compared to other models. There was no correlation between visual analogue pain scale and the total BPCS-C score; however, there was an association between pain catastrophizing and difficulty in doing physical activities in school (p = 0.01). BPCS-C total scores were not different between groups. We found a marginal association with BPCS-C (r = 0.27, p = 0.01) and salivary BDNF levels. DISCUSSION: BPCS-C is a valid instrument with consistent psychometric properties. The revised 2-dimension proposed can be used for this population. Children catastrophism is well correlated with physical limitation, but the absence of BPCS-C score differences between groups highlights the necessity of a better understanding about catastrophic thinking in children. AD - Universidade Federal do Rio Grande do Sul (UFRGS), Faculdade de Medicina, Programa de Pós-graduação em Ciências Médicas, Porto Alegre, RS, Brazil; Hospital de Clínicas de Porto Alegre (HCPA), Serviço de Anestesia e Medicina Perioperatória, Porto Alegre, RS, Brazil; Hospital de Clínicas de Porto Alegre (HCPA), Laboratório de Dor e Neuromodulação, Porto Alegre, RS, Brazil. Universidade Federal do Rio Grande do Sul (UFRGS), Departamento de Estatística, Porto Alegre, RS, Brazil. Hospital de Clínicas de Porto Alegre (HCPA), Serviço de Anestesia e Medicina Perioperatória, Porto Alegre, RS, Brazil. Hospital de Clínicas de Porto Alegre (HCPA), Laboratório de Dor e Neuromodulação, Porto Alegre, RS, Brazil. Universidade Federal do Rio Grande do Sul (UFRGS), Faculdade de Medicina, Porto Alegre, RS, Brazil. Hospital de Clínicas de Porto Alegre (HCPA), Serviço de Anestesia e Medicina Perioperatória, Porto Alegre, RS, Brazil; Hospital de Clínicas de Porto Alegre (HCPA), Laboratório de Dor e Neuromodulação, Porto Alegre, RS, Brazil; Universidade Federal do Rio Grande do Sul (UFRGS), Faculdade de Medicina, Departamento de Cirurgia, Porto Alegre, RS, Brazil. Hospital de Clínicas de Porto Alegre (HCPA), Serviço de Anestesia e Medicina Perioperatória, Porto Alegre, RS, Brazil; Hospital de Clínicas de Porto Alegre (HCPA), Laboratório de Dor e Neuromodulação, Porto Alegre, RS, Brazil; Universidade Federal do Rio Grande do Sul (UFRGS), Faculdade de Medicina, Departamento de Cirurgia, Porto Alegre, RS, Brazil. Electronic address: lpstefani@hcpa.edu.br. AN - 33932395 AU - Schneider, L. AU - Castro, S. M. J. AU - Mallman, E. S. AU - Evaldt, C. A. AU - Souza, A. AU - Rodrigues, J. D. S. AU - Mendanha, C. AU - Caumo, W. AU - Stefani, L. C. DA - Apr 28 DO - 10.1016/j.bjane.2021.02.057 DP - NLM ET - 2021/05/02 KW - Brain-Derived Neurotrophic Factor (BDNF) Catastrophizing Children Chronic pain Pain catastrophizing Validation studies as topic LA - eng N1 - 0104-0014 Schneider, Larissa Castro, Stela Maris de Jezus Mallman, Eliza Saggin Evaldt, Cibelle de Abreu Souza, Andressa Rodrigues, Josy da Silva Mendanha, Clarissa Caumo, Wolnei Stefani, Luciana Cadore Journal Article Brazil Braz J Anesthesiol. 2021 Apr 28:S0104-0014(21)00178-0. doi: 10.1016/j.bjane.2021.02.057. PY - 2021 ST - Validation of the Brazilian version of the child pain catastrophizing scale and its relationship with a marker of central sensitization T2 - Braz J Anesthesiol TI - Validation of the Brazilian version of the child pain catastrophizing scale and its relationship with a marker of central sensitization ID - 4195 ER - TY - JOUR AB - While the biopsychosocial nature of inflammatory bowel disease (IBD) is now well accepted by clinicians, the need for integrated multidisciplinary care is not always clear to institutional administrators who serve as decision makers regarding resources provided to clinical programs. In this commentary, we draw on our own experience in building successful integrated care models within a division of pediatric gastroenterology (GI) to highlight key considerations in garnering initial approval, as well as methods to maintain institutional support over time. Specifically, we discuss the importance of making a strong case for the inclusion of a psychologist in pediatric IBD care, justifying an integrated model for delivering care, and addressing finances at the program level. Further, we review the benefit of collecting and reporting program data to support the existing literature and/or theoretical projections, demonstrate outcomes, and build alternative value streams recognized by the institution (e.g., academic, reputation) alongside the value to patients. Ultimately, success in garnering and maintaining institutional support necessitates moving from the theoretical to the practical, while continually framing discussion for a nonclinical/administrative audience. While the process can be time-consuming, ultimately it is worth the effort, enhancing the care experience for both patients and clinicians. AN - WOS:000642920700001 AU - Schurman, J. V. AU - Friesen, C. A. C7 - 286 DA - Apr DO - 10.3390/children8040286 IS - 4 N1 - Schurman, Jennifer Verrill Friesen, Craig A. 2227-9067 PY - 2021 ST - Leveraging Institutional Support to Build an Integrated Multidisciplinary Care Model in Pediatric Inflammatory Bowel Disease T2 - Children-Basel TI - Leveraging Institutional Support to Build an Integrated Multidisciplinary Care Model in Pediatric Inflammatory Bowel Disease UR - ://WOS:000642920700001 VL - 8 ID - 1744 ER - TY - JOUR AB - Background Migraine is one of the most common pain symptoms in childhood, a chronic disease with recurrent symptoms that lead to a reduction of daily activities during the intercritical periods, with an impact of the quality of life. Objective The aim of this publication is to investigate, in which extent migraine affects the quality of life of children and adolescents, how strong they are restricted in everyday life and in which areas such restrictions can be found. Results The parents of children with FSH (frequent or severe headaches) reported that the children had difficulties with emotions, concentration, behaviour, and were unable to get along with others. Children with FSH were significantly more likely to be upset or distressed by their difficulties, while experiencing disappointments, and to have these difficulties interfere with home life, friendships and classroom learning (Strine et al., 2006). Moreover, mothers described children with migraine as evidencing higher levels of internalizing behaviour and symptoms of anxiety and depression. Children with migraine indicated more negative self-perceptions of their physical appearance (Vannatta et al., 2008). Children with migraine lost school activity and performance, household tasks and leisure. Furthermore, it was observed that children with migraine went to school but didn't show a good performance because of physical or mental health problems (Ferracini, Dach & Speciali, 2013). Conclusion Compared to children without migraine, children and adolescents with migraine have generally poorer qualities of life in different areas. AN - 30387969 AU - Schwingshackl, P. AU - Rungger, G. AU - Mantovan, F. DA - Dec DP - NLM ET - 2016/12/01 IS - 12 KW - Activities of Daily Living/classification/psychology Adolescent Child Cross-Sectional Studies Humans Internal-External Control Interpersonal Relations Migraine Disorders/epidemiology/etiology/*nursing/*psychology Parent-Child Relations Quality of Life/*psychology Risk Factors Social Adjustment LA - eng ger N1 - Schwingshackl, Petra Rungger, Gregorio Mantovan, Franco Journal Article Review Germany Kinderkrankenschwester. 2016 Dec;35(12):463-465. OP - Auswirkungen der Migrane auf die Lebens-qualitat von Kindern und Jugendlichen. PY - 2016 SN - 0723-2276 (Print) 0723-2276 SP - 463-465 ST - [Not Available] T2 - Kinderkrankenschwester TI - [Not Available] VL - 35 ID - 2971 ER - TY - JOUR AB - One hundred eighty patients with acute low-back pain (LBP) were compared to 608 age- and sex-matched controls with regard to somatic and personality characteristics. The low-back-pain group had a fourfold increase (median) in sick-leave episodes for reasons other than spinal morbidity during the preceding 2 years. In the same period, the median number of episodes of sick leave for LBP was 1 in the patients and 0 in the controls. The mean number of days off for other reasons was 34 (median = 20.5) in the patients compared to 9 (median = 0) in the controls, and days off for LBP were 20 (median = 5) and 5 (median = 0), respectively. Analysis of other factors than those directly related to LBP disclosed significant differences in marital status and smoking habits between patients and controls. Furthermore, LBP patients estimated their work to be physically heavier. We conclude that medical intervention should focus not only on the spine, but also on a wide range of other aspects of the patient's situation. Even in the acute phase of LBP, the previous sick-leave records should be analyzed to provide adequate measures to prevent future sick leaves. Presently, the sociomedical costs for a subset of the population who repeatedly seek help for LBP are significantly higher than those for the non-LBP population. AD - Department of Orthopedics, Karolinska Hospital, Stockholm, Sweden. AN - 10451042 AU - Seferlis, T. AU - Németh, G. AU - Carlsson, A. M. AU - Gillström, P. DA - Aug DP - NLM ET - 1999/08/18 IS - 4 KW - *Absenteeism Acute Disease Adolescent Adult Case-Control Studies Comorbidity Disability Evaluation Female Humans Low Back Pain/*epidemiology/therapy Male Medical Records Middle Aged Occupations Pain Measurement Personality Inventory Physical Examination Prospective Studies Sciatica/epidemiology Surveys and Questionnaires Sweden/epidemiology Treatment Outcome LA - eng N1 - Seferlis, T Németh, G Carlsson, A M Gillström, P Clinical Trial Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't United States J Spinal Disord. 1999 Aug;12(4):280-6. PY - 1999 SN - 0895-0385 (Print) 0895-0385 SP - 280-6 ST - Acute low-back-pain patients exhibit a fourfold increase in sick leave for other disorders: a case-control study T2 - J Spinal Disord TI - Acute low-back-pain patients exhibit a fourfold increase in sick leave for other disorders: a case-control study VL - 12 ID - 3578 ER - TY - JOUR AB - BACKGROUND: As part of the rural outreach programme and school health programme of Santosh Hospital, medical examination of school children, studying in Government Primary and Middle Schools of the nine villages where the outreach programme was in progress, was carried out. AIMS AND OBJECTIVES: The aim of this study was to find out the morbidity profile, nutritional status and level of personal hygiene of the school children. MATERIAL AND METHODS: A team of doctors examined all the students of the concerned schools on a fixed date. Health status was assessed by detailed clinical history and thorough check-up by resident doctors in Ophthalmology, ENT, Pediatrics and Dentistry. Level of personal hygiene was assessed by checking the cleanliness of clothes, hair, nails, face and freedom from any skin infections. Nutritional status was assessed by calculating Body Mass Index (BMI) and the weight status was then classified according to WHO BMI for AGE classification. The study was conducted between 04 August 2014 to 21 November 2014 and a total of 421 students were examined. RESULTS: Maximum (41.33%) children were found to have dental caries, followed by anemia in 11.64% students. Fever and upper respiratory tract infections were found in 9.5% children and defective vision in 3.09% students. Complaints of pain abdomen was given by 2.38% children and 2.85% of them gave history of worm infestation. A number of students were found to be suffering from skin infections like pyoderma (4.99%), scabies (3.09%) and fungal infections (2.61%). CONCLUSIONS: The government health department should regularly carry out school health check-up as well as health education sessions to educate the children, parents as well as school teachers on various preventive measures including improvement in nutritional status and personal hygiene. AN - WOS:000377777400015 AU - Sehgal, R. K. AU - Garg, R. AU - Anand, S. AU - Dhot, P. S. AU - Singhal, P. DA - Sep DO - 10.14260/jemds/2015/1810 IS - 72 N1 - Sehgal, Ravi Kant Garg, Rinku Anand, Sharmila Dhot, Paramjit Singh Singhal, Parul 2278-4802 PY - 2015 SN - 2278-4748 SP - 12574-12580 ST - A STUDY OF THE MORBIDITY PROFILE, PERSONAL HYGIENE AND NUTRITIONAL STATUS OF SCHOOL CHILDREN IN RURAL AREAS OF DISTRICT GHAZIABAD IN UTTAR PRADESH T2 - Journal of Evolution of Medical and Dental Sciences-Jemds TI - A STUDY OF THE MORBIDITY PROFILE, PERSONAL HYGIENE AND NUTRITIONAL STATUS OF SCHOOL CHILDREN IN RURAL AREAS OF DISTRICT GHAZIABAD IN UTTAR PRADESH UR - ://WOS:000377777400015 VL - 4 ID - 2223 ER - TY - JOUR AB - Objective. To determine prevalence of exposure to bullying in an adolescent/young adult gynecology population, whether pelvic pain is an associated somatic complaint, and if health care providers are viewed as a resource. Methods. An anonymous self-reporting survey about exposure to bullying, somatic and mental health symptoms, and disclosure patterns was given to 224 consecutive gynecology patients aged 15 to 24 years in a suburban practice. Results. Prevalence of exposure as a bully, victim, witness, or combination was 80.5%. Missing school for pelvic pain was significantly greater in the bully-victim-witness and victim-witness groups. Taking medication for depression or anxiety was significantly greater in the bully-victim-witness group. No one disclosed bullying exposure to a health care provider. Conclusions. Gynecologists see large numbers of patients exposed to bullying. Patients exposed in combinations of bully, victim, and witness have increased frequency of pelvic pain, depression, and anxiety. Patients do not disclose exposure to bullying to health care providers. AN - WOS:000314475300007 AU - Seltzer, M. B. AU - Long, R. A. DA - Feb DO - 10.1177/0009922812468207 IS - 2 N1 - Seltzer, Marlene B. Long, Robert A. 1938-2707 PY - 2013 SN - 0009-9228 SP - 156-161 ST - Bullying in an Adolescent and Young Adult Gynecology Population T2 - Clinical Pediatrics TI - Bullying in an Adolescent and Young Adult Gynecology Population UR - ://WOS:000314475300007 VL - 52 ID - 2383 ER - TY - JOUR AB - INTRODUCTION: Worldwide, about 90% of people are infected with the herpes simplex virus, 30% of whom will experience recurrent herpes simplex labialis, commonly referred to as 'cold sores', which can last up to 10 days. The most common treatment is aciclovir cream which reduces healing time by just half a day compared with no specific treatment. This is a protocol for a randomised controlled trial (RCT) to determine the efficacy of medical grade kanuka honey-based topical treatment (Honevo) in reducing the healing time and pain of cold sores, compared with topical aciclovir treatment (Viraban). METHODS AND ANALYSIS: This open-label, parallel-group, active comparator superiority RCT will compare the efficacy of medical grade kanuka honey with 5% aciclovir cream in the treatment of cold sores in the setting of a pharmacy research network of 60 sites throughout New Zealand. Adults presenting with a cold sore (N=950) will be randomised by pharmacy-based investigators. The pharmacy-based investigators will dispense the investigational product to randomised participants and both study groups apply the treatment five times daily until their skin returns to normal or for 14 days, whichever occurs first. In response to a daily SMS message, participants complete an assessment of their cold sore healing, with reference to a visual guide, and transmit it to the investigators by a smartphone eDiary in real time. The primary outcome variable is time (in days) from randomisation to return to normal skin. Secondary endpoints include total healing time stratified by stage of the lesion at onset of treatment, highest pain severity and time to pain resolution. ETHICS AND DISSEMINATION: New Zealand Ethics Registration 15/NTB/93. Results will be published in a peer-reviewed medical journal, presented at academic meetings and reported to participants. TRIAL REGISTRATION NUMBER: Australia New Zealand Clinical Trials Registry: ACTRN12615000648527, pre-results.SCOTT Registration: 15/SCOTT/14 PROTOCOL VERSION: 4.0 (12 June 2017). AD - Medical Research Institute of New Zealand, Wellington, New Zealand. Victoria University Wellington, Wellington, New Zealand. AN - 28775197 AU - Semprini, A. AU - Singer, J. AU - Shortt, N. AU - Braithwaite, I. AU - Beasley, R. C2 - PMC5724166 DA - Aug 3 DO - 10.1136/bmjopen-2017-017766 DP - NLM ET - 2017/08/05 IS - 8 KW - Acyclovir/pharmacology/*therapeutic use Administration, Topical Adolescent Adult Aged Antiviral Agents/pharmacology/*therapeutic use *Apitherapy Herpes Labialis/drug therapy/pathology/virology Herpes Simplex/*drug therapy/pathology/virology *Honey Humans *Kunzea Middle Aged New Zealand Pain/drug therapy/etiology Recurrence Research Design *Simplexvirus Skin/drug effects/virology Treatment Outcome aciclovir cold sore herpes simplex kanuka honey pharmacy research LA - eng N1 - 2044-6055 Semprini, Alex Orcid: 0000-0003-0949-0555 Singer, Joseph Shortt, Nicholas Braithwaite, Irene Orcid: 0000-0001-5327-3027 Beasley, Richard Pharmacy Research Network Comparative Study Journal Article Randomized Controlled Trial BMJ Open. 2017 Aug 3;7(8):e017766. doi: 10.1136/bmjopen-2017-017766. PY - 2017 SN - 2044-6055 SP - e017766 ST - Protocol for a randomised controlled trial of 90% kanuka honey versus 5% aciclovir for the treatment of herpes simplex labialis in the community setting T2 - BMJ Open TI - Protocol for a randomised controlled trial of 90% kanuka honey versus 5% aciclovir for the treatment of herpes simplex labialis in the community setting VL - 7 ID - 3814 ER - TY - JOUR AB - Introduction: There is limited knowledge about the associations of Helicobacter pylori (H. pylori) infections in developing countries. This study aimed to determine the current prevalence and associations of H. pylori infection with breastfeeding practices, nutritional status, and recurrent abdominal pain (RAP) in a group of apparently healthy children and adolescents in Lagos, Nigeria. Methodology: This was a prospective hospital-based study conducted at the Lagos State University Teaching Hospital that involved 118 children who came to the hospital for routine pediatric care. Seroprevalence status of the children was determined by measuring immunoglobulin G antibodies against H. pylori using enzyme-linked immunosorbent assay (ELISA). Results: Seventy-five (63.6%) children were seropositive for H. pylori. The prevalence of H. pylori infection increased significantly from 40.4% in children less than five years of age to 85.1% at six to ten years of age (chi(2) = 20.9, p < 0.001). H. pylori infection was associated with low social class (OR = 3.24; 95% CI = 1.20-8.23, p = 0.016) and with RAP (OR = 3.47; 95% CI = 1.55-7.79, p = 0.002), but no association was observed with exclusive breastfeeding, duration of breastfeeding, and under-nutrition. Conclusions: The prevalence of H. pylori infection is high, particularly among children from low socioeconomic backgrounds in Lagos, Nigeria. It is associated with RAP. The effect of this infection on children's health requires further studies. AN - WOS:000339927900008 AU - Senbanjo, I. O. AU - Oshikoya, K. A. AU - Njokanma, O. F. DA - Apr DO - 10.3855/jidc.3196 IS - 4 N1 - Senbanjo, Idowu O. Oshikoya, Kazeem A. Njokanma, Olisamedua F. Oshikoya, Kazeem/0000-0003-3662-8476 PY - 2014 SN - 1972-2680 SP - 448-453 ST - Helicobacter pylori associated with breastfeeding, nutritional status and recurrent abdominal pain in healthy Nigerian children T2 - Journal of Infection in Developing Countries TI - Helicobacter pylori associated with breastfeeding, nutritional status and recurrent abdominal pain in healthy Nigerian children UR - ://WOS:000339927900008 VL - 8 ID - 2310 ER - TY - JOUR AB - Objectives University students with pain face unique physical, psychological, social and academic challenges, but research on this is limited. The main aim of this study was to examine how pain, disability and perceived social support relate to psychological and academic outcomes in students with pain. It also compared students with pain and students without pain on measures of depression, anxiety and perceived social support. Methods Three hundred and eleven students enrolled in Chinese universities took part in the study, 198 with pain (102 reported acute pain and 96 chronic pain) and 113 without pain. They completed measures of perceived social support, depression, anxiety, pain (intensity, frequency, duration), disability and pain interference with academic functioning. Results Students with chronic pain reported higher levels of anxiety and depression and lower levels of perceived social support than students without pain. There were no significant differences between students with acute and chronic pain, and between students with acute pain and those without pain. In the pain sample (containing both acute and chronic pain group), greater interference with academic functioning was predicted by higher levels of pain and disability, and disability also predicted higher levels of depression. After controlling for effects of pain and disability, lower levels of perceived social support predicted higher levels of both anxiety and depression. Conclusions These results highlight the role of pain and disability in academic functioning and the role of perceived social support in psychological functioning of students with pain. AD - Department of Psychology, Royal Holloway, University of London, Egham, Surrey, TW20 0EX, UK. Department of Psychology, Royal Holloway, University of London, Egham, Surrey, UK. AN - 32562531 AU - Serbic, D. AU - Zhao, J. AU - He, J. DA - Jun 22 DO - 10.1515/ijamh-2019-0032 DP - NLM ET - 2020/06/21 KW - academic functioning at-risk youth pain psychological functioning social support LA - eng N1 - 2191-0278 Serbic, Danijela Zhao, Jun He, Jiafan Journal Article Germany Int J Adolesc Med Health. 2020 Jun 22:/j/ijamh.ahead-of-print/ijamh-2019-0032/ijamh-2019-0032.xml. doi: 10.1515/ijamh-2019-0032. PY - 2020 SN - 0334-0139 ST - The role of pain, disability and perceived social support in psychological and academic functioning of university students with pain: an observational study T2 - Int J Adolesc Med Health TI - The role of pain, disability and perceived social support in psychological and academic functioning of university students with pain: an observational study ID - 4091 ER - TY - JOUR AB - Introduction: Although there are many studies on functional somatic symptoms (FSS), there are few conducted with Spanish samples. The aim of this study was to assess the prevalence of frequent functional somatic symptoms in a Spanish sample, and to look for relationships with psychopathology and parenting styles. Patients and methods: The sample consisted of 672 participants from 6 to 8 years-old attending primary school in the region of Osona (Catalonia, Spain). The parents reported on the presence of FSS in children, school absence, paediatric visits; psychiatric symptoms, and parenting styles. Children who complained of frequent somatic symptoms (four or more in the previous fortnight) were compared with children who did not complain. Results: A total of 429 of the 672 (63.8%) children had at least one physical complaint during the two weeks prior to the study. Almost one quarter (162, 24.1%) of the participants had frequent FSS. Significant relationships were found with, separation anxiety, social phobia, and visits to the paediatrician. A small effect of overprotection/control parenting style on FSS was observed. Conclusions: Functional somatic symptoms are common in a Spanish sample of children between 6 to 8 years-old. These children may be considered a risk group for future emotional distress. It is also important for future research to clarify the nature of the relationship between overprotection and FSS. (C) 2012 Asociacion Espanola de Pediatria. Published by Elsevier Espana, S.L. All rights reserved. AN - WOS:000322861600007 AU - Serra, R. AU - Jane, M. C. AU - Bonillo, A. DA - Aug DO - 10.1016/j.anpedi.2012.09.008 IS - 2 N1 - Serra, R. Claustre Jane, M. Bonillo, A. Bonillo, Albert/H-9927-2015 Bonillo, Albert/0000-0002-6141-9708 PY - 2013 SN - 1695-4033 SP - 101-107 ST - Functional somatic symptoms in a Spanish sample: Psychopathology and educational styles T2 - Anales De Pediatria TI - Functional somatic symptoms in a Spanish sample: Psychopathology and educational styles UR - ://WOS:000322861600007 VL - 79 ID - 2359 ER - TY - JOUR AB - Bruxism is the non-functional clenching or grinding of the teeth that may occur during sleep or less commonly in daytime. The aim of this study was to investigate the association between clinical signs and symptoms, parafunctions and associated factors of sleep bruxism in children. A population-based case-control study was carried out involving 120 children, 8 years of age, with sleep bruxism and 240 children without sleep bruxism. The sample was randomly selected from public and private schools in the city of Belo Horizonte, MG, Brazil. Groups were matched by gender and social class. The Social Vulnerability Index (SVI) drawn up by the city of Belo Horizonte was employed for social classification. Data collection instruments included clinical forms and pre-tested questionnaires. The diagnosis of sleep bruxism was supported by the American Association of Sleep Medicine (AASM) criteria. The McNemar test, binary and multivariate logistic regression models were used for statistical analysis. The risk factors associated with sleep bruxism included: primary canine wear (OR=2.3 IC 95% 1.2-4.3), biting of objects like pencils or pens (OR=2.0 IC 95% 1.2-3.3) and wake-time bruxism (tooth clenching) (OR=2.3 IC 95% 1.2-4.3). Children that present the parafunctions of object biting and wake-time bruxism were more susceptible to sleep bruxism. AD - Department of Pediatric Dentistry and Orthodontics, UFMG - Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil. juniaserranegra@hotmail.com AN - 23338271 AU - Serra-Negra, J. M. AU - Paiva, S. M. AU - Auad, S. M. AU - Ramos-Jorge, M. L. AU - Pordeus, I. A. DO - 10.1590/s0103-64402012000600020 DP - NLM ET - 2013/01/23 IS - 6 KW - Brazil/epidemiology Bruxism/epidemiology Case-Control Studies Child Cuspid/pathology Dental Occlusion, Traumatic/epidemiology Female Headache/epidemiology Humans Male Malocclusion/epidemiology Mouth Breathing/epidemiology Population Surveillance Risk Factors Sleep Bruxism/*epidemiology Social Class Socioeconomic Factors Temporomandibular Joint Disorders/epidemiology Temporomandibular Joint Dysfunction Syndrome/epidemiology Tooth Wear/epidemiology Tooth, Deciduous/pathology Vulnerable Populations/statistics & numerical data LA - eng N1 - 1806-4760 Serra-Negra, Júnia Maria Paiva, Saul Martins Auad, Sheyla Márcia Ramos-Jorge, Maria Letícia Pordeus, Isabela Almeida Comparative Study Journal Article Research Support, Non-U.S. Gov't Brazil Braz Dent J. 2012;23(6):746-52. doi: 10.1590/s0103-64402012000600020. PY - 2012 SN - 0103-6440 SP - 746-52 ST - Signs, symptoms, parafunctions and associated factors of parent-reported sleep bruxism in children: a case-control study T2 - Braz Dent J TI - Signs, symptoms, parafunctions and associated factors of parent-reported sleep bruxism in children: a case-control study VL - 23 ID - 3842 ER - TY - JOUR AB - BACKGROUND: Occupational physical demands are commonly assumed the cause of work-related Low Back Pain (LBP) and absenteeism. OBJECTIVES: To analyse relationships between LBP at work, physical demands and absenteeism. METHODS: Workers filled out a questionnaire on socio-demographic and work-related factors, general health, LBP (number of episodes in a 12-month period, pain severity and intensity), and occupational hazards related with physical demands. RESULTS: 735 workers completed the questionnaire (male n = 359). A high proportion of workers n = 507 (69%), from different occupational backgrounds, reported at least one LBP episode in the previous 12-month period. The highest ratio of subjects with more than 6 episodes of LBP per year was found among public services employees (31.8%) and the lowest ratio among administrative workers (10.3%). The highest ratio of workers (39%) were classified as sedentary workers, 34% of workers having a low or moderate level of physical demands in their work, and 27% reported high levels of physical demands in their work. There was a 4 % absenteeism rate in a 12-month period, which was significantly higher in the group with physically demanding work. Those subjects with higher physical requirements at work have increased odds of having more than 3 episodes of LBP during the previous year (p < 0.05) in comparison with subjects with more sedentary jobs and those with low or moderate physical demands. High intensity work, compared to sedentary work, is associated with an increased probability of being absent of work because of LBP in a previous 12-month period (OR = 3.12; CI 1.23-7.89; p = 0.016). CONCLUSIONS: Our findings suggest there is an association between highly physically demanding jobs, LBP and absenteeism. These results may contribute to the improvement of LBP assessment and prevention programs in Occupational Health Services. AD - CISP - Public Health Research Center, NOVA National School of Public Health, Lisbon, Portugal. Comprehensive Health Research Center (CHRC), Lisbon, Portugal. Clinical Investigator, Occupational Doctor, Lisbon, Portugal. Unidad de la Espalda Kovacs. Hospital Universitario HLA-Moncloa, y Red Española de Investigadores en Dolencias de la Espalda, Madrid, Spain. AN - 32007966 AU - Serranheira, F. AU - Sousa-Uva, M. AU - Heranz, F. AU - Kovacs, F. AU - Sousa-Uva, A. DO - 10.3233/wor-203073 DP - NLM ET - 2020/02/03 IS - 2 KW - *Absenteeism Adolescent Adult Ergonomics Female Humans Low Back Pain/*epidemiology/etiology Male Middle Aged Occupational Diseases/epidemiology/etiology Portugal/epidemiology Risk Factors Sciatica/epidemiology Surveys and Questionnaires Workload/*statistics & numerical data Occupational health occupational disorders LA - eng N1 - 1875-9270 Serranheira, F Sousa-Uva, M Heranz, F Kovacs, F Sousa-Uva, A Journal Article Netherlands Work. 2020;65(2):463-469. doi: 10.3233/WOR-203073. PY - 2020 SN - 1051-9815 SP - 463-469 ST - Low Back Pain (LBP), work and absenteeism T2 - Work TI - Low Back Pain (LBP), work and absenteeism VL - 65 ID - 2969 ER - TY - JOUR AB - Cross-sectional associations were examined between pain catastrophizing and several health indices in 1,164 people with musculoskeletal pain from a Dutch community sample. Health indices included in the present study were specialist consultation, use of medication, and absenteeism or work disability. The results demonstrate that for people with a current episode of musculoskeletal pain, pain catastrophizing, pain intensity, and the presence of multiple pain locations were significantly associated with specialist consultation, use of pain medication, and absenteeism or work disability. The authors conclude that the role of pain itself has perhaps been underestimated in recent models of chronic pain-related disability. Some clinical implications and suggestions for further research are given. AD - Department of Medical Psychology, University Hospital of Maastricht, Maastricht, The Netherlands. r.severeijns@smps.azm.nl AN - 14756603 AU - Severeijns, R. AU - Vlaeyen, J. W. AU - van den Hout, M. A. AU - Picavet, H. S. DA - Jan DO - 10.1037/0278-6133.23.1.49 DP - NLM ET - 2004/02/06 IS - 1 KW - Adolescent Adult Aged Catchment Area, Health Cohort Studies Cross-Sectional Studies Female Humans Male Middle Aged Musculoskeletal Diseases/diagnosis/*epidemiology Netherlands/epidemiology Pain/diagnosis/*epidemiology/*psychology Pain Measurement Severity of Illness Index Surveys and Questionnaires LA - eng N1 - Severeijns, Rudy Vlaeyen, Johan W S van den Hout, Marcel A Picavet, H Susan J Journal Article United States Health Psychol. 2004 Jan;23(1):49-57. doi: 10.1037/0278-6133.23.1.49. PY - 2004 SN - 0278-6133 (Print) 0278-6133 SP - 49-57 ST - Pain catastrophizing is associated with health indices in musculoskeletal pain: a cross-sectional study in the Dutch community T2 - Health Psychol TI - Pain catastrophizing is associated with health indices in musculoskeletal pain: a cross-sectional study in the Dutch community VL - 23 ID - 4118 ER - TY - JOUR AB - STUDY DESIGN: A cross-sectional survey by anonymous self-assessment questionnaire was given to 3600 high school students from 30 high schools. OBJECTIVE: The purpose of this study was to analyze the prevalence of neck and shoulder pain (NSP) and its effects among high school students in Shanghai, China. SUMMARY OF BACKGROUND DATA: NSP has become a problem in many countries in recent years among adolescents. No recent studies have estimated the prevalence of NSP in Chinese school populations. METHODS: A total of 3600 high school students from all 3 grades chosen from 30 random schools participated in this study. Participants were asked to fill out a questionnaire on NSP and to provide information on demographic items, family factors, schooling, and lifestyles. χ tests were used to compare the incidence of NSP, univariate and multivariate logistic regression analyses were used to obtain influencing factors of NSP. RESULTS: In total, 3600 questionnaires were distributed, and 2842 were valid. The cross-sectional prevalence of NSP was 41.1%, with more girls (653 of 1478, i.e., 44.2%) reporting having NSP than boys (514 of 1364, i.e., 37.7%) (odds ratio = 0.764; 95% confidence interval = 0.657-0.888; P < 0.05). The frequency, duration, and degree of NSP in girls were also higher than in boys. For high school years 1, 2, and 3, the incidence of NSP was 40.1%, 40.7%, and 45.4%, respectively. The multivariate logistic regression indicated that sex, family history of NSP, school furniture, long sitting time, computer use, insufficient rest time, sleep time, commuting method, perceived schoolbag weight, and smoking had a significant effect on NSP. CONCLUSION: The incidence of NSP in high school students in Shanghai is quite high. The occurrence of NSP is related to several factors including sex and school year, as well as some factors related to family, schooling, and lifestyles. LEVEL OF EVIDENCE: 3. AU - Shan, Zhi AU - Deng, Guoying AU - Li, Jipeng AU - Li, Yangyang AU - Zhang, Yongxing AU - Zhao, Qinghua DA - 2014/02/15/ DO - 10.1097/BRS.0000000000000124 DP - PubMed IS - 4 J2 - Spine (Phila Pa 1976) KW - Adolescent China Cross-Sectional Studies Female Humans Life Style Male Neck Pain Prevalence Risk Factors Schools Sex Factors Shoulder Pain Students Surveys and Questionnaires LA - eng PY - 2014 SN - 1528-1159 SP - E276-283 ST - How schooling and lifestyle factors effect neck and shoulder pain? T2 - Spine TI - How schooling and lifestyle factors effect neck and shoulder pain? A cross-sectional survey of adolescents in China UR - http://www.ncbi.nlm.nih.gov/pubmed/24253782 VL - 39 ID - 91 ER - TY - JOUR AB - Background: Patients with non-inflamed appendix have been reported to have had more hospitalizations and emotional disorders before and after the operation than patients with acute appendicitis. Objectives: To compare abdominal pain characteristics, as well as demographic and psychosocial data in children with histologically confirmed appendicitis compared to non-inflamed appendices. Methods: Charts of children with suspected appendicitis who had undergone appendectomy were retrospectively reviewed for relevant clinical and laboratory data. The patients or their parents were then contacted by phone and were asked to respond to a detailed questionnaire on abdominal symptoms as well as demographic and psychosocial data. Results: The study group comprised 156 children: 117 with histologically confirmed appendicitis and 39 with normal appendices. Eighty-two patients (53.2%) were located and interviewed: 62 (54%) with appendicitis and 20 (51%) with normal appendices. Of the 82 children, 16 reported recurrent episodes of abdominal pain before or after surgery: 11 (17.7%) in the appendicitis group and 5 (25%) in the normal appendix group. Only six patients fulfilled the formal criteria for the diagnosis of recurrent abdominal pain: 5 (8%) from the appendicitis group and 1 (5%) from the non-inflamed appendix group (not significant). In addition, no significant statistical differences were found between the groups regarding school performance, behavior and social interaction with peers. Conclusions: We could not demonstrate an increased incidence of recurrent abdominal pain, nor could we identify significant psychosocial morbidity in those children undergoing an appendectomy for a non-inflamed appendix. AN - WOS:000261446600017 AU - Shaoul, R. AU - Ghrayeb, N. AU - Hardoff, D. DA - Nov IS - 11 N1 - Shaoul, Ron Ghrayeb, Nabil Hardoff, Daniel Shaoul, Ron/S-7737-2019 Shaoul, Ron/0000-0001-5667-8759 PY - 2008 SN - 1565-1088 SP - 812-815 ST - Recurrent Abdominal Pain Before and After Appendectomy T2 - Israel Medical Association Journal TI - Recurrent Abdominal Pain Before and After Appendectomy UR - ://WOS:000261446600017 VL - 10 ID - 2631 ER - TY - JOUR AB - Some children and adolescents with sickle cell disease experience frequent painful episodes. To gain information about the natural history of the pain and its impact on sleep and school attendance, we developed a home-based diary system. Eighteen children and adolescents completed 4756 diary days, with an average compliance of 75%. Pain was reported on 30% of days and was managed at home nine-tenths of the time. Girls reported more days with pain than did boys, and age was positively correlated with the length of the painful episodes. The pain affected school attendance and sleep. Patients were absent from school on 21% of 3186 school days, with half of the absenteeisms on days with reported pain. Of the pain-associated absenteeisms, two-thirds occurred when pain was managed at home, and one-third when patients were hospitalized. The average consecutive number of school days missed was 2.7. These findings have implications for developmentally critical activities. AN - WOS:A1995QW07700018 AU - Shapiro, B. S. AU - Dinges, D. F. AU - Orne, E. C. AU - Bauer, N. AU - Reilly, L. B. AU - Whitehouse, W. G. AU - Ohenefrempong, K. AU - Orne, M. T. DA - Apr DO - 10.1016/0304-3959(94)00164-a IS - 1 N1 - Shapiro, bs dinges, df orne, ec bauer, n reilly, lb whitehouse, wg ohenefrempong, k orne, mt Dinges, David/P-7183-2019 1872-6623 PY - 1995 SN - 0304-3959 SP - 139-144 ST - HOME MANAGEMENT OF SICKLE CELL-RELATED PAIN IN CHILDREN AND ADOLESCENTS - NATURAL-HISTORY AND IMPACT ON SCHOOL ATTENDANCE T2 - Pain TI - HOME MANAGEMENT OF SICKLE CELL-RELATED PAIN IN CHILDREN AND ADOLESCENTS - NATURAL-HISTORY AND IMPACT ON SCHOOL ATTENDANCE UR - ://WOS:A1995QW07700018 VL - 61 ID - 2940 ER - TY - JOUR AB - Pelvic and lower abdominal pain constitutes more than 30% of the referrals to our adolescent medicine and gastroenterology clinics. These cases are responsible for numerous school absences and significant cost to the healthcare system. This article will review the most common causes of lower abdominal and pelvic pain in adolescents, diagnostic and management issues, as well as prevention. AN - WOS:000242314300012 AU - Shashidhar, H. AU - Omar, H. A. DA - Jan DO - 10.1100/tsw.2005.10 N1 - Shashidhar, Harohalli Omar, Hatim A. PY - 2005 SN - 1537-744X SP - 64-70 ST - Recurrent lower abdominal pain in older children and adolescents: Revised clinical approach T2 - Thescientificworldjournal TI - Recurrent lower abdominal pain in older children and adolescents: Revised clinical approach UR - ://WOS:000242314300012 VL - 5 ID - 2780 ER - TY - JOUR AB - The development, implementation, and qualitative evaluation of smartphone-based pain management applications may provide an opportunity for more optimal management of pediatric pain in the homesetting. The present mixed-method study was conducted to assess a smartphone-based pain management application regarding the feasibility, adherence, participant satisfaction, and effectiveness on pain intensity and quality of life in adolescents with chronic pain. The study was carried out in the quantitative and qualitative stages using a mixed-method approach. The quantitative stage included 128 adolescents who met the ICD-11 criteria of chronic pain. After random allocation, adolescents allocated to the intervention group received a pain management program through a smartphone-based application. No education was given to the adolescents in the control group. The adolescents were assessed regarding pain intensity and different dimensions of quality of life at pre-intervention, post-intervention, and three-month follow-up. The findings in the quantitative stage were explained by qualitative interviews. The findings of the quantitative stage showed significant improvements in the pain intensity, emotional, social, and school functioning but not in the physical functioning of the adolescents. A high level of adherence (78.12%) and satisfaction (Mean=26.45, SD=6.45) with thes martphone-based pain management program was found. Based on the qualitative interviews, adolescents' pain management strategies can be classified in three main categories: physical management, psychological management, and interpersonal resources. The results confirm the positive effect of a smartphone-based pain management program on the pain intensity and different dimensions of quality of life of adolescents with chronic pain. Within the context of chronic pain management, a mobile application incorporating both the psychological and physical management of pain may help adolescents with chronic pain to reduce the negative impacts of pain on their life. AN - WOS:000634964500002 AU - Shaygan, M. AU - Jaberi, A. C7 - 6588 DA - Mar DO - 10.1038/s41598-021-86156-8 IS - 1 N1 - Shaygan, Maryam Jaberi, Azita PY - 2021 SN - 2045-2322 ST - The effect of a smartphone-based pain management application on pain intensity and quality of life in adolescents with chronic pain T2 - Scientific Reports TI - The effect of a smartphone-based pain management application on pain intensity and quality of life in adolescents with chronic pain UR - ://WOS:000634964500002 VL - 11 ID - 1746 ER - TY - JOUR AB - Introduction Chronic pain negatively affects adolescents' quality of life. Therefore, it is important to seek for ways to effectively manage pain, which may, in turn, promote quality-of-life dimensions in this population. However, there are many barriers including geographical distance which prevent most adolescents from receiving an effective treatment for chronic pain. The present study aimed to investigate the effect of a smartphone-based pain management application compared with face-to-face pain management program and wait-list control on the pain intensity and quality-of-life dimensions in adolescents with chronic pain. Methods This study used a cluster double-blinded randomized parallel-group design with school as the unit of randomization. Participants included were 192 adolescents with chronic pain. The questionnaires (pain intensity and quality of life measuring physical, emotional, social, and school dimensions) were completed at the baseline, immediately at the end of pain management program and three months after the end of the program. Results Repeated measures ANOVAs with adjustment for clustering effect showed that there were significant main effects of time on ratings of pain intensity (p < 0.01), physical (p < 0.005), emotional (p < 0.008), social (p < 0.001), and school (p < 0.005) dimensions of quality of life. There was also a significant main effect of group on ratings of emotional (p < 0.001), social (p < 0.009), and school (p < 0.002) dimensions. The interaction of group x time for emotional (p < 0.004), social (p < 0.001), and school (p < 0.005) dimensions of quality of life was statistically significant. Discussion The findings suggest that smartphone-based pain management program, which is a highly accessible and cost-effective intervention, may provide benefits similar to a face-to-face intervention and shows promise for being effective on emotional, social, and school dimensions of quality of life in adolescents with different types of chronic pain. The study was registered within the Iranian Registry of Clinical Trials (IRCT20180808040744N2). AN - WOS:000656512000001 AU - Shaygan, M. AU - Jahandide, Z. AU - Zarifsanaiey, N. DO - 10.1007/s11136-021-02891-5 N1 - Shaygan, Maryam Jahandide, Zahra Zarifsanaiey, Nahid Zarifsanaiey, Nahid/M-8789-2017; Shaygan, Maryam/H-8101-2016 Zarifsanaiey, Nahid/0000-0002-1297-8271; Shaygan, Maryam/0000-0002-1456-9340 1573-2649 SN - 0962-9343 ST - An investigation of the effect of smartphone-based pain management application on pain intensity and the quality-of-life dimensions in adolescents with chronic pain: a cluster randomized parallel-controlled trial T2 - Quality of Life Research TI - An investigation of the effect of smartphone-based pain management application on pain intensity and the quality-of-life dimensions in adolescents with chronic pain: a cluster randomized parallel-controlled trial UR - ://WOS:000656512000001 ID - 1737 ER - TY - JOUR AB - The clinical and psychological findings on 100 children with psychosomatic musculoskeletal pain seen at a major pediatric rheumatology referral center are reported. Most (76%) were female, median age was 13 years, and median duration of symptoms was 1 year. Multiple painful sites were common (66%). The pain was constant (63%) or intermittent (37%); 45% had hyperesthesia, and almost all maintained a cheerful affect when complaining of severe pain. Two predominant abnormal family milieu were seen. One was cohesive, stable, and organized, but intolerant of separation and individuation. The other was chaotic, emotionally unsupportive, with high levels of conflict. Members of the cohesive family type reported significantly less distress than members of chaotic families. Enmeshment between mother and child was common in both family types. Although frequently viewed as bright, most of these children had normal intelligence, and some had unrecognized academic difficulty. These children, compared with those with arthritis, had a significantly lower global well-being score. Clinical depression was unusual (11%). Most (97%) responded favorably to intensive physical and occupational therapy along with individual or family psychotherapy; 78% become symptom free or fully functional. Children with these signs and symptoms should have full psychological evaluations and respond well to treatment directed toward decreasing pain and restoring function. AD - Children's Hospital and Medical Center, University of Washington, Seattle. AN - 1956724 AU - Sherry, D. D. AU - McGuire, T. AU - Mellins, E. AU - Salmonson, K. AU - Wallace, C. A. AU - Nepom, B. DA - Dec DP - NLM ET - 1991/12/01 IS - 6 KW - Adolescent Child Child, Preschool Family Female Humans Male Musculoskeletal Diseases/*psychology Pain/etiology/*psychology Pain Management Psychological Tests Psychophysiologic Disorders/*psychology Psychotherapy Stress, Psychological LA - eng N1 - Sherry, D D McGuire, T Mellins, E Salmonson, K Wallace, C A Nepom, B Case Reports Journal Article United States Pediatrics. 1991 Dec;88(6):1093-9. PY - 1991 SN - 0031-4005 (Print) 0031-4005 SP - 1093-9 ST - Psychosomatic musculoskeletal pain in childhood: clinical and psychological analyses of 100 children T2 - Pediatrics TI - Psychosomatic musculoskeletal pain in childhood: clinical and psychological analyses of 100 children VL - 88 ID - 3491 ER - TY - JOUR AB - Purpose: To report the efficacy of hydroxyurea (HU) in a patient with sickle cell anemia (SCA) associated with systemic lupus erythematosus (SLE). Patients and Methods: An unusual association of SCA with SLE occurred in a 14-year-old black girl. Her medical history was significant for repeated vasoocclusive crises requiring repeated hospitalizations and transfusions, acute chest syndrome, hyperhemolytic crises, multiple transfusions resulting in iron overload, gall stones, avascular necrosis, and significant psychosocial problems. Her lupus activity was controlled with oral prednisone and hydroxychloroquine. Treatment with oral HU was instituted at an initial dose of 20 mg/kg with gradual increment to a maximum of 25 mg/kg daily. Results: A dramatic clinical improvement was noted with HU therapy with no episode of pain crisis or hospitalization for 5 months. There was an increase in fetal hemoglobin (HbF) to 20.9% and mean corpuscular volume to 114.5 fl, but her Hb level remained steady at 7.5 g/dl. No toxicity was noted with HU therapy. In addition, a significant change was also observed in her school performance, social activities, and general quality of life. Conclusions: HU therapy may be beneficial and safe and should be considered for other patients who have SCA with SLE. AN - WOS:000075123600011 AU - Shetty, A. K. AU - Kumar, S. R. AU - Gedalia, A. AU - Warrier, R. P. DA - Jul-Aug DO - 10.1097/00043426-199807000-00011 IS - 4 N1 - Shetty, AK Kumar, SR Gedalia, A Warrier, RP Warrier, Rajasekharan P/D-4512-2011 Shetty, Avinash/0000-0002-4575-8996 PY - 1998 SN - 1077-4114 SP - 335-337 ST - Sickle cell anemia with systemic lupus erythematosus: Response to hydroxyurea therapy T2 - Journal of Pediatric Hematology Oncology TI - Sickle cell anemia with systemic lupus erythematosus: Response to hydroxyurea therapy UR - ://WOS:000075123600011 VL - 20 ID - 2893 ER - TY - JOUR AB - Nasogastric (NG) intubation is a common yet one of the most uncomfortable minor procedures done in children and adults alike. A variety of analgesics, such as ketamine, lidocaine, and nitrous oxide, have been shown to reduce pain in various minor pediatric procedures. This retrospective study explores how often various pain management practices are used, either alone or in combination. The study examines NG intubation in pediatrics in one pediatric academic health system. The comfort measures used include analgesics, distraction, child life, swaddling, nitrous oxide, and others. Pharmacological intervention (analgesics) and distraction were most frequently used. Larger randomized studies should be conducted to determine the best practices for comfort measures for NG intubation in order to achieve maximal pain and anxiety reduction for children of various ages. AN - WOS:000453652400039 AU - Shih, S. AU - Rosen, P. C7 - e3429 DA - Oct DO - 10.7759/cureus.3429 IS - 10 N1 - Shih, Shawn Rosen, Paul 2168-8184 PY - 2018 ST - Pain Management for Nasogastric Intubation in Pediatrics T2 - Cureus TI - Pain Management for Nasogastric Intubation in Pediatrics UR - ://WOS:000453652400039 VL - 10 ID - 1987 ER - TY - JOUR AB - We studied seventy patients, 23 males and 47 females with irritable bowel syndrome in adolescence aged 13-19 yrs, who visited the department of psychosomatic medicine in Takano Hospital during about six year period of April, 1986-July, 1992. Takano Hospital is a coloproctological center in Kumamoto. In the clinical pattern of adolescent patients with irritable bowel syndrome the "gas" pattern was dominant (51.4%). Patients with the gas pattern have severe symptoms of flatus, fullness, rumbling sound and abdominal pain as well as bowel dysfunction, constipation and diarrhea in a classroom. Next, the diarrheal pattern occurred in 20.0%. Diarrheal patients complained of frequent bowel movements and retention feelings before attending school. Recurrent abdominal pain-like pattern was found in 7.1% patients. Clinical symptoms in the adolescent patients seem to derived from a mental tension and stress in a close classroom or before attending school. Many adolescenct patients (67.1%) with irritable bowel syndrome are embarrassed in school-maladjustment; leaving class early, late coming, a long absence, and a withdrawal. AD - Department of Psychosomatic Medicine, Fukuoka Takano Hospital. AN - 1363122 AU - Shimada, A. AU - Takano, M. DA - Nov DP - NLM ET - 1992/11/01 IS - 11 KW - Adolescent Adult Age Factors Anti-Anxiety Agents/therapeutic use Colonic Diseases, Functional/classification/etiology/*physiopathology Female Humans Male Psychotherapy Sex Factors Social Environment Stress, Psychological/complications Trimebutine/therapeutic use LA - jpn N1 - Shimada, A Takano, M English Abstract Journal Article Review Japan Nihon Rinsho. 1992 Nov;50(11):2729-33. PY - 1992 SN - 0047-1852 (Print) 0047-1852 SP - 2729-33 ST - [Irritable bowel syndrome in adolescence] T2 - Nihon Rinsho TI - [Irritable bowel syndrome in adolescence] VL - 50 ID - 3987 ER - TY - JOUR AB - Educator Perceptions and ratings of pain between school age children with and without mental retardation were investigated using written vignettes of three different pain types (acute/procedural; accidental; chronic). Diagnostic/functional information (i.e., mental retardation) was randomized across raters (N = 95). Raters were asked to consider whether the child experienced any pain (yes/no) and if so to rate its intensity on a standardized numeric rating scale. There were no significant differences between groups for the Perception of pain or the rating of pain intensity by diagnostic/functioning information. Additional analyses showed that participants rated pain differently across pain types (p <.05) suggesting that the written vignettes had face validity (i.e., represented different types/sources of pain). Secondary analyses between licensed special education teachers and prospective pre-licensure special education teachers found significant differences (p <.05) between ratings for acute/procedural pain. These results suggest that more experienced (i.e., licensed) teachers may be better 'detectors' of pain/discomfort in children with or without mental retardation than less experienced teachers. Implications of this finding are discussed. Considering the limited research in the area of pain, disability, and education further work appears warranted. AN - WOS:000246717200009 AU - Shinde, S. K. AU - Symons, F. DA - Jun IS - 2 N1 - Shinde, Satomi K. Symons, Frank PY - 2007 SN - 1547-0350 SP - 224-229 ST - Educator perceptions and ratings of pain in school-age children with mental retardation and developmental disabilities T2 - Education and Training in Developmental Disabilities TI - Educator perceptions and ratings of pain in school-age children with mental retardation and developmental disabilities UR - ://WOS:000246717200009 VL - 42 ID - 2687 ER - TY - JOUR AB - BACKGROUND: Although neurologic sequela is a recognized complication after interscalene brachial plexus block (ISB), there is a paucity of information on how severe and persistent neuropathy occurs and develops. CASE PRESENTATION: A healthy high school soccer goalkeeper was scheduled for an arthroscopic Bankart repair. After continuous ISB for 2 days, sensation in the C5 and C6 areas and motor function did not return. With symptomatic drug treatment for neuropathic pain and rigorous rehabilitation, recovery of sensory loss and muscle weakness were gradually observed around 1 to 2 months after surgery. He returned to sport 1 year after surgery. CONCLUSION: This report is the first detailed description of a case who incurred severe and persistent nerve injury after continuous ISB yet recovered nearly fully to return to being an athlete. The present case should also underscore the importance of close observation after surgery in cases where a patient receives continuous ISB. AD - Department of Anesthesiology, Shimane University Faculty of Medicine, 89-1 Enya-Cho, Izumo City, Shimane, 693-8501, Japan. h.shio@hotmail.co.jp. Surgical Operation Center, Shimane University Hospital, 89-1 Enya-Cho, Izumo City, Shimane, 693-8501, Japan. Department of Anesthesiology, Shimane University Faculty of Medicine, 89-1 Enya-Cho, Izumo City, Shimane, 693-8501, Japan. Department of Rehabilitation Medicine, Shimane University Faculty of Medicine, 89-1 Enya-Cho, Izumo City, Shimane, 693-8501, Japan. AN - 32062710 AU - Shio, H. AU - Sakura, S. AU - Motooka, A. AU - Sakai, Y. AU - Saito, Y. C2 - PMC7024071 DA - Feb 15 DO - 10.1186/s40981-020-0315-1 DP - NLM ET - 2020/02/18 IS - 1 KW - Continuous interscalene brachial plexus block Magnetic resonance imaging Neurological complication Neurophysiological measurements Rehabilitation LA - eng N1 - 2363-9024 Shio, Hisashi Sakura, Shinichi Motooka, Akihiro Sakai, Yasuo Saito, Yoji Journal Article JA Clin Rep. 2020 Feb 15;6(1):15. doi: 10.1186/s40981-020-0315-1. PY - 2020 SN - 2363-9024 SP - 15 ST - Severe and persistent nerve palsy after ultrasound-guided continuous interscalene brachial plexus block in a teenager undergoing shoulder surgery: a case report T2 - JA Clin Rep TI - Severe and persistent nerve palsy after ultrasound-guided continuous interscalene brachial plexus block in a teenager undergoing shoulder surgery: a case report VL - 6 ID - 4184 ER - TY - JOUR AB - It is well known that children need solicitous parenting and a nurturing rearing environment to ensure their normal behavioral development. Early adversity often negatively impacts emotional and mental well-being, but it is less clearly established how much the maturation and regulation of physiological systems is also compromised. The following research investigated the effect of 2 different types of adverse childhood experiences, early deprivation through institutionalization and physical abuse, on a previously unexplored outcome: the containment of herpes simplex virus (HSV). The presence of HSV-specific antibody in salivary specimens was determined in 155 adolescents, including 41 postinstitutionalized, 34 physically-abused, and 80 demographically-similar control youth. Across 4 school and home days, HSV antibody was higher in both postinstitutionalized and physically-abused adolescents when compared with control participants. Because the prevalence of HSV infection was similar across the groups, the elevated antibody was likely indicative of viral recrudescence from latency. Total secretory Ig-A secretion was associated with HSV, but did not account for the group differences in HSV-specific antibody. These findings are likely caused by a failure of cellular immune processes to limit viral reactivation, indicating a persistent effect of early rearing on immune functioning. The fact that antibody profiles were still altered years after adoption into a more benevolent setting with supportive families suggests these results were not caused by contemporaneous factors, but rather reflect a lingering influence of earlier life experiences. AN - WOS:000263652900088 AU - Shirtcliff, E. A. AU - Coe, C. L. AU - Pollak, S. D. DA - Feb DO - 10.1073/pnas.0806660106 IS - 8 N1 - Shirtcliff, Elizabeth A. Coe, Christopher L. Pollak, Seth D. Pollak, Seth D/G-2345-2011 PY - 2009 SN - 0027-8424 SP - 2963-2967 ST - Early childhood stress is associated with elevated antibody levels to herpes simplex virus type 1 T2 - Proceedings of the National Academy of Sciences of the United States of America TI - Early childhood stress is associated with elevated antibody levels to herpes simplex virus type 1 UR - ://WOS:000263652900088 VL - 106 ID - 2614 ER - TY - JOUR AB - Background: Primary headaches are remarkably prevalent worldwide and are increasingly reported among children. However, the exact trend in this age group, particularly in the Gulf region, remains largely unknown. Aims and Objectives: To examine the prevalence of primary headache disorders among primary and middle school students in Kuwait. Methods: We conducted a cross-sectional study that included Kuwaiti primary and middle school children and adolescents of both genders in randomly selected schools located in two governorates in Kuwait in the 2018/2019 academic year. Prevalence and attributable burden of headaches, definite and probable migraines, definite and probable tension-type headaches, chronic headaches (>= 15 days/month), and probable medication-overuse headaches were assessed using the Headache-Attributed Restriction, Disability, Social Handicap, and Impaired Participation (HARDSHIP) questionnaire for children and adolescents. Results: Of 1,485 questionnaires that were distributed, 1,089 students completed the questionnaire with a respondent rate of 73.4%. The study population consisted of 420 boys (38.56%) and 669 girls (61.43%) students with a mean age of 11.5 +/- 2.11 years. The 1-year prevalence of primary headache disorders was 42.78%, with more middle schoolers reporting headaches than primary schoolers (50.37 vs. 30.48%; p < 0.02). The mean age of students with primary headaches was 11.98 +/- 2.03 years in both genders. When stratified according to diagnostic criteria, migraine headaches were the most frequently reported (20.75%), followed by tension type headaches (18.8%), chronic headaches (2.75%), and probable medication-overuse headaches (0.46%). Primary headaches were significantly higher in girls compared to boys among middle schoolers (66.46 vs. 38.49%; p < 0.001); however, no significant difference between genders was noted among primary school students (33.12 vs. 22.33%; p < 0.118). Conclusion: Primary headaches are remarkably common in Kuwaiti school students, with migraine headaches being the most frequently reported type. Age and female gender may play a role in the development of primary headaches. These findings necessitate the direction of health services and research efforts toward this age group and warrant the need for further epidemiological studies. AN - WOS:000618224000001 AU - Shuaibi, S. AU - AlAshqar, A. AU - Ahmed, S. F. AU - Alroughani, R. AU - AlThufairi, H. AU - Owayed, S. AU - AlHamdan, F. AU - Al-Hashel, J. C7 - 621017 DA - Feb DO - 10.3389/fneur.2021.621017 N1 - Shuaibi, Sameera AlAshqar, Abdelrahman Ahmed, Samar Farouk Alroughani, Raed AlThufairi, Hawraa Owayed, Shaikhah AlHamdan, Fajer Al-Hashel, Jasem AlAshqar, Abdelrahman/ABB-2545-2020 AlAshqar, Abdelrahman/0000-0002-1283-7460 PY - 2021 SN - 1664-2295 ST - Primary Headache Disorder Among School Students in Kuwait T2 - Frontiers in Neurology TI - Primary Headache Disorder Among School Students in Kuwait UR - ://WOS:000618224000001 VL - 12 ID - 1756 ER - TY - JOUR AB - Purpose: To examine the effectiveness of intensive interdisciplinary pain treatment for improving disability in children with chronic headache using the International Classification of Functioning, Disability and Health model as a conceptual framework for disability assessment.Materials and methods: Children with chronic headache (n = 50; ages 10-19 years; 62% female) attended an intensive interdisciplinary pain treatment program 8 h/day, 5 times/week for 2-7 weeks. Disability measures were administered at admission, discharge, and 6-8 week follow-up. Disability outcomes were analyzed retrospectively. Wilcoxon signed rank tests and Friedman's analyses of variance were used to compare scores across two and three longitudinal time points, respectively.Results: After rehabilitation, disability reduced on the Headache Impact Test-6 from severe impact at admission to some impact at follow-up (p < 0.001). Median time on the modified Bruce protocol increased from 13.1 min (interquartile range = 12.6-14.1) to 14.4 min (interquartile range = 12.9-16.3), p < 0.001, with gains maintained at follow-up. Improvements in pain and disability were associated with improvements in school participation.Conclusions: Findings of this study support the effectiveness of intensive interdisciplinary pain treatment for improving disability in children with chronic headache.Implication for rehabilitationIntensive interdisciplinary pain treatment is effective for improving pain and disability in children with chronic headaches.Application of the ICF model to disability assessment suggests that children with chronic headaches may experience significant disability, even when standardized assessments of physical capacity are normal.The modified Bruce protocol, Pediatric Evaluation of Disability Inventory - Computerized Adaptive Tests, and Headache Impact Test-6 appear particularly valuable in understanding the nature of disability in children with chronic headaches. AD - Department of Physical and Occupational Therapy, Boston Children's Hospital, Boston, MA, USA. MGH Institute of Health Professions, Boston, MA, USA. Mayo Family Pediatric Pain Rehabilitation Center, Boston Children's Hospital, Boston, MA, USA. Department of Psychiatry, Harvard Medical School, Boston, MA, USA. Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, MA, USA. Department of Psychology, West Virginia University, Morgantown, WV, USA. Department of Neurology, Boston Children's Hospital, Boston, MA, USA. Department of Anesthesiology, Harvard Medical School, Boston, USA. AN - 32406759 AU - Shulman, J. AU - Conroy, C. AU - Cybulski, A. AU - Smith, K. R. AU - Jervis, K. AU - Johnson, H. AU - Zurakowski, D. AU - Sethna, N. F. DA - May 14 DO - 10.1080/09638288.2020.1762125 DP - NLM ET - 2020/05/15 KW - Headache chronic pain disability evaluation interdisciplinary health team rehabilitation LA - eng N1 - 1464-5165 Shulman, Julie Orcid: 0000-0002-5530-9692 Conroy, Caitlin Cybulski, Anna Smith, Kelly R Jervis, Kelsey Johnson, Hannah Zurakowski, David Sethna, Navil F Journal Article England Disabil Rehabil. 2020 May 14:1-8. doi: 10.1080/09638288.2020.1762125. PY - 2020 SN - 0963-8288 SP - 1-8 ST - Does intensive interdisciplinary pain treatment improve pediatric headache-related disability? T2 - Disabil Rehabil TI - Does intensive interdisciplinary pain treatment improve pediatric headache-related disability? ID - 4169 ER - TY - JOUR AB - PURPOSE AND PATIENTS AND METHODS: Lyme disease is a major clinical problem in a number of endemic areas in the United States. In areas where anxiety about the disease is high, patients and physicians often ascribe clinical concerns to Lyme disease. Incorrect diagnosis often leads to unnecessary antibiotic treatment (often prolonged or repeated intravenous therapy). This report summarizes the cases of the first 100 patients referred to the Lyme Disease Center at Robert Wood Johnson Medical School. RESULTS: In only 37 of the patients referred was Lyme disease, either current or preceding, the explanation for the complaints. Many of the patients had another definable arthropathy. Twenty-five of the patients had fibromyalgia, which has not previously been reported in Lyme disease. Three of these patients had active Lyme disease at the time of evaluation, and 17 had a history suggesting preceding Lyme disease. Approximately half of the 91 courses of antibiotic therapy given to these 100 patients before referral were probably unwarranted. CONCLUSIONS: Anxiety about possible late manifestations of Lyme disease has made Lyme disease a "diagnosis of exclusion" in many endemic areas. Persistence of mild to moderate symptoms after adequate therapy and misdiagnosis of fibromyalgia and fatigue may incorrectly suggest persistence of infection, leading to further antibiotic therapy. Attention to patient anxiety and increased awareness of these musculoskeletal problems after therapy should decrease unnecessary therapy of previously treated Lyme disease. AD - Department of Medicine, Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903-0019. AN - 2346158 AU - Sigal, L. H. DA - Jun DO - 10.1016/0002-9343(90)90520-n DP - NLM ET - 1990/06/01 IS - 6 KW - Adolescent Adult Aged Anti-Bacterial Agents/therapeutic use Antibodies, Bacterial/analysis Arthritis, Infectious/diagnosis Borrelia burgdorferi Group/immunology Child Child, Preschool Diagnosis, Differential Erythema Chronicum Migrans/diagnosis Female Fibromyalgia/diagnosis Humans Lyme Disease/blood/*diagnosis/drug therapy Male Middle Aged Referral and Consultation Retrospective Studies LA - eng N1 - Sigal, L H Journal Article United States Am J Med. 1990 Jun;88(6):577-81. doi: 10.1016/0002-9343(90)90520-n. PY - 1990 SN - 0002-9343 (Print) 0002-9343 SP - 577-81 ST - Summary of the first 100 patients seen at a Lyme disease referral center T2 - Am J Med TI - Summary of the first 100 patients seen at a Lyme disease referral center VL - 88 ID - 3623 ER - TY - JOUR AB - Previous studies indicate that childhood sexual abuse can have extensive and serious consequences. The aim of this research was to do a qualitative study of the consequences of childhood sexual abuse for Icelandic mens health and well-being. Phenomenology was the methodological approach of the study. Totally 14 interviews were conducted, two per individual, and analysed based on the Vancouver School of Phenomenology. The main results of the study showed that the men describe deep and almost unbearable suffering, affecting their entire life, of which there is no alleviation in sight. The men have lived in repressed silence most of their lives and have come close to taking their own lives. What stopped them from committing suicide was revealing to others what happened to them which set them free in a way. The men experienced fear- or rage-based shock at the time of the trauma and most of them endured the attack by dissociation, disconnecting psyche and body and have difficulties reconnecting. They had extremely difficult childhoods, living with indisposition, bullying, learning difficulties and behavioural problems. Some have, from a young age, numbed themselves with alcohol and elicit drugs. They have suffered psychologically and physically and have had relational and sexual intimacy problems. The consequences of the abuse surfaced either immediately after the shock or many years later and developed into complex post-traumatic stress disorder. Because of perceived societal prejudice, it was hard for the men to seek help. This shows the great need for professionals to be alert to the possible consequences of childhood sexual abuse in their practice to reverse the damaging consequences on their health and well-being. We conclude that living in repressed silence after a trauma, like childhood sexual abuse, can be dangerous for the health, well-being and indeed the very life of the survivor. AN - WOS:000310791200009 AU - Sigurdardottir, S. AU - Halldorsdottir, S. AU - Bender, S. S. DA - Dec DO - 10.1111/j.1471-6712.2012.00981.x IS - 4 N1 - Sigurdardottir, Sigrun Halldorsdottir, Sigridur Bender, Soley S. Halldorsdottir, Sigridur/B-7165-2016; Sigurdardottir, Sigrun/J-4326-2019 Halldorsdottir, Sigridur/0000-0003-0629-4428; Sigurdardottir, Sigrun/0000-0003-2898-3240; Bender, Soley Sesselja/0000-0001-6205-7131 1471-6712 PY - 2012 SN - 0283-9318 SP - 688-697 ST - Deep and almost unbearable suffering: consequences of childhood sexual abuse for men's health and well-being T2 - Scandinavian Journal of Caring Sciences TI - Deep and almost unbearable suffering: consequences of childhood sexual abuse for men's health and well-being UR - ://WOS:000310791200009 VL - 26 ID - 2407 ER - TY - JOUR AB - BackgroundChildhood sexual abuse (CSA) survivors deal with complex mental, physical and relationship problems in adulthood which negatively affects their well-being and health. The aim of the present paper was to present a description of the Wellness-Program for female CSA survivors, the participating women's evaluation of the different therapies in the program as well as a qualitative study on their experience of the program's effects on their life, health and well-being. MethodThe Wellness-Program lasted for 10weeks with organised schedule 20hours per week. A team of health professionals used a holistic approach and provided traditional and complementary individual and group therapy focusing on both mind and body. In-depth phenomenological interviews with ten women, 22-53years old, were conducted 1week before and 1week after the program as well as 15months later. Data collection and data analysis were guided by the Vancouver School of doing phenomenology. ResultsPrior to participating in the program, the women were unable to work or attend school, were on disability allowance, were socially isolated and had complex health problems. After the Wellness-Program, all the women, except one, were back to work, school or in further rehabilitation. Furthermore, the in-depth interviews showed that their health and well-being, personal life and relationship with partners, family and friends improved. They felt empowered, more in control and had developed increased trust towards others. Six themes were constructed from the in-depth interviews. They were: feeling totally lost, releasing experiences, developing trusting relationships, gaining control, experiencing positive changes in physical and mental health and, finally, feeling of empowerment. The overriding theme of the study was personal resurrection. ConclusionsThe Wellness-Program contributed considerably to improved health and well-being of the women. However, further assessment of the program is recommended before making it available within the healthcare system. AN - WOS:000371477400019 AU - Sigurdardottir, S. AU - Halldorsdottir, S. AU - Bender, S. S. AU - Agnarsdottir, G. DA - Mar DO - 10.1111/scs.12238 IS - 1 N1 - Sigurdardottir, Sigrun Halldorsdottir, Sigridur Bender, Soley S. Agnarsdottir, Gudrun Sigurdardottir, Sigrun/J-4326-2019; Halldorsdottir, Sigridur/B-7165-2016 Sigurdardottir, Sigrun/0000-0003-2898-3240; Halldorsdottir, Sigridur/0000-0003-0629-4428; Bender, Soley Sesselja/0000-0001-6205-7131 1471-6712 PY - 2016 SN - 0283-9318 SP - 175-186 ST - Personal resurrection: female childhood sexual abuse survivors' experience of the Wellness-Program T2 - Scandinavian Journal of Caring Sciences TI - Personal resurrection: female childhood sexual abuse survivors' experience of the Wellness-Program UR - ://WOS:000371477400019 VL - 30 ID - 2182 ER - TY - JOUR AB - Study Objective: Pain management in emergency department (ED) patients is challenging. Although both pharmacological and nonpharmacological therapies exist, they are often suboptimal. Immersive virtual reality (VR) uses distraction and possible other methods to reduce perceptions of pain. The purpose of the study is to evaluate the usability and acceptability of VR applications in ED patients by assessing patient-reported changes in pain, anger, and anxiety levels. Methods: This is a prospective cohort study at a single academic urban tertiary care center among ED patients with a pain score ≥3 on a numeric rating scale (0-10 integers) for any reason. Patients with stroke, epilepsy, dementia, or other diseases that may prevent use of VR were excluded. Enrolled patients in the intervention cohort spent 20 min using VR applications. A paired t test was used to analyze the change of pain, anger, and anxiety scores between pre- and postintervention. Analysis of variance and linear regression were used to assess the impact of other subject variables (including gender, age, race, and education) on pre-post intervention changes. Results: One hundred (N = 100) patients were enrolled in this study and 93 experienced the VR intervention. Of these, 57 (61.3%) were women, and mean age was 38 ± 14. Mean anger (2.28 ± 0.8 to 1.92 ± 0.7, p < 0.0001), anxiety (2.06 ± 0.8 to 1.81 ± 0.8, p < 0.0001), and pain (7.16 ± 2.5 to 6.49 ± 2.7, p < 0.0001) levels dropped significantly from pre- to postintervention. Outcomes of the VR intervention were impacted by subject variables, including education and ethnicity. Pain (1.86 ± 3.3, p = 0.03) and anger (1.03 ± 1.4, p = 0.02) levels dropped most for those with less than high school education. Linear regression analysis revealed that patients with higher levels of health/quality of life (QOL) had larger mean drop per unit predictor for anger (0.29 [0.09], p = 0.0013) and anxiety (0.22 [0.07], p = 0.001). Conclusions: VR applications are feasible for ED patients and may lead to reduced pain, anger, and anxiety levels. These outcomes are affected by subject ethnicity, educational status, and health/QOL although independent of the chief complaint. AD - Department of Emergency Medicine, School of Medicine and Health Sciences, George Washington University, Washington, District of Columbia. Department of Surgery, School of Medicine and Health Sciences, George Washington University, Washington, District of Columbia. AN - 30785860 AU - Sikka, N. AU - Shu, L. AU - Ritchie, B. AU - Amdur, R. L. AU - Pourmand, A. DA - Dec DO - 10.1089/tmj.2018.0273 DP - NLM ET - 2019/02/21 IS - 12 KW - Adult *Anger Management Therapy *Emergency Service, Hospital Female Humans Male *Pain Management Pain Measurement Prospective Studies Psychiatric Status Rating Scales Quality of Life *Virtual Reality Exposure Therapy *anger *anxiety *e-Health *emergency department *pain *telehealth *telemedicine *virtual reality LA - eng N1 - 1556-3669 Sikka, Neal Shu, Liqi Ritchie, Brandon Amdur, Richard L Pourmand, Ali Journal Article United States Telemed J E Health. 2019 Dec;25(12):1207-1215. doi: 10.1089/tmj.2018.0273. Epub 2019 Feb 20. PY - 2019 SN - 1530-5627 SP - 1207-1215 ST - Virtual Reality-Assisted Pain, Anxiety, and Anger Management in the Emergency Department T2 - Telemed J E Health TI - Virtual Reality-Assisted Pain, Anxiety, and Anger Management in the Emergency Department VL - 25 ID - 3820 ER - TY - JOUR AB - BACKGROUND: Cancer incidence in Middle Eastern countries, most categorized as low- and middle-income, is predicted to double in the next 10 years, greater than in any other part of the world. While progress has been made in cancer diagnosis/treatment, much remains to be done to improve palliative care for the majority of patients with cancer who present with advanced disease. OBJECTIVE: To determine knowledge, beliefs, barriers, and resources regarding palliative care services in Middle Eastern countries and use findings to inform future educational and training activities. DESIGN: Descriptive survey. SETTING/SUBJECTS: Fifteen Middle Eastern countries; convenience sample of 776 nurses (44.3%), physicians (38.3%) and psychosocial, academic, and other health care professionals (17.4%) employed in varied settings. MEASUREMENTS: Palliative care needs assessment. RESULTS: Improved pain management services are key facilitators. Top barriers include lack of designated palliative care beds/services, community awareness, staff training, access to hospice services, and personnel/time. The nonexistence of functioning home-based and hospice services leaves families/providers unable to honor patient wishes. Respondents were least satisfied with discussions around advance directives and wish to learn more about palliative care focusing on communication techniques. Populations requiring special consideration comprise: patients with ethnic diversity, language barriers, and low literacy; pediatric and young adults; and the elderly. CONCLUSIONS: The majority of Middle Eastern patients with cancer are treated in outlying regions; the community is pivotal and must be incorporated into future plans for developing palliative care services. Promoting palliative care education and certification for physicians and nurses is crucial; home-based and hospice services must be sustained. AD - 1 Middle East Cancer Consortium, Technion-Israel Institute of Technology , Haifa, Israel . AN - 25302525 AU - Silbermann, M. AU - Fink, R. M. AU - Min, S. J. AU - Mancuso, M. P. AU - Brant, J. AU - Hajjar, R. AU - Al-Alfi, N. AU - Baider, L. AU - Turker, I. AU - ElShamy, K. AU - Ghrayeb, I. AU - Al-Jadiry, M. AU - Khader, K. AU - Kav, S. AU - Charalambous, H. AU - Uslu, R. AU - Kebudi, R. AU - Barsela, G. AU - Kuruku, N. AU - Mutafoglu, K. AU - Ozalp-Senel, G. AU - Oberman, A. AU - Kislev, L. AU - Khleif, M. AU - Keoppi, N. AU - Nestoros, S. AU - Abdalla, R. F. AU - Rassouli, M. AU - Morag, A. AU - Sabar, R. AU - Nimri, O. AU - Al-Qadire, M. AU - Al-Khalaileh, M. AU - Tayyem, M. AU - Doumit, M. AU - Punjwani, R. AU - Rasheed, O. AU - Fallatah, F. AU - Can, G. AU - Ahmed, J. AU - Strode, D. DA - Jan DO - 10.1089/jpm.2014.0194 DP - NLM ET - 2014/10/11 IS - 1 KW - Adult Health Care Surveys *Health Knowledge, Attitudes, Practice *Health Personnel Hospice Care/*organization & administration Humans Middle East *Needs Assessment Neoplasms/*therapy Palliative Care/*organization & administration LA - eng N1 - 1557-7740 Silbermann, Michael Fink, Regina M Min, Sung-Joon Mancuso, Mary P Brant, Jeannine Hajjar, Ramzi Al-Alfi, Nesreen Baider, Lea Turker, Ibrahim ElShamy, Karima Ghrayeb, Ibtisam Al-Jadiry, Mazin Khader, Khaled Kav, Sultan Charalambous, Haris Uslu, Ruchan Kebudi, Rejin Barsela, Gil Kuruku, Nilgün Mutafoglu, Kamer Ozalp-Senel, Gulsin Oberman, Amitai Kislev, Livia Khleif, Mohammad Keoppi, Neophyta Nestoros, Sophia Abdalla, Rasha Fahmi Rassouli, Maryam Morag, Amira Sabar, Ron Nimri, Omar Al-Qadire, Mohammad Al-Khalaileh, Murad Tayyem, Mona Doumit, Myrna Punjwani, Rehana Rasheed, Osaid Fallatah, Fatimah Can, Gulbeyaz Ahmed, Jamila Strode, Debbie Evaluation Study Journal Article Research Support, Non-U.S. Gov't United States J Palliat Med. 2015 Jan;18(1):18-25. doi: 10.1089/jpm.2014.0194. PY - 2015 SN - 1557-7740 SP - 18-25 ST - Evaluating palliative care needs in Middle Eastern countries T2 - J Palliat Med TI - Evaluating palliative care needs in Middle Eastern countries VL - 18 ID - 4219 ER - TY - JOUR AB - A representative epidemiological study on the occurrence of migraine and other headaches in Finnish schoolchildren 14 years of age is presented. The investigation covered 3863 pupils, accounting for 94.2% of the total of 4101 mentally normal children, who went to school in two big Finnish cities. There were 1954 boys and 1909 girls in the study. They were given a one-page questionnaire with four questions concerning the frequency and the nature of headache in themselves and their family members. Considerable attention was paid to the wording and unambiguity of each question. The forms were filled in under the control of the home-room teacher, whose check-up of the answers was intended to remove discrepancies between the filled-in forms and the children's complaints. For the clinically working physician, especially the general practitioner, it is worthwhile noticing that during the last 12 months not less than 68% of the 14-year-old schoolchildren had suffered from headache. Headache had been less frequent in the boys (65%) than in the girls (71%). In 10.2% of the schoolchildren migraine attacks had occurred. Again, the boys had migraine less frequently (6.7%) than the girls (13.8%). The combination of individual migraine factors, which occurred in one third of the cases, was unilateral pain and migraine in other family members. The figures are similar to those in another investigation of headaches in schoolchildren. AN - 6545051 AU - Sillanpää, M. AU - Piekkala, P. DA - Feb DO - 10.3109/02813438409017698 DP - NLM ET - 1984/02/01 IS - 1 KW - Adolescent Female Finland Headache/*epidemiology Humans Male Migraine Disorders/*epidemiology *Puberty Recurrence LA - eng N1 - Sillanpää, M Piekkala, P Journal Article Research Support, Non-U.S. Gov't United States Scand J Prim Health Care. 1984 Feb;2(1):27-32. doi: 10.3109/02813438409017698. PY - 1984 SN - 0281-3432 (Print) 0281-3432 SP - 27-32 ST - Prevalence of migraine and other headaches in early puberty T2 - Scand J Prim Health Care TI - Prevalence of migraine and other headaches in early puberty VL - 2 ID - 3330 ER - TY - JOUR AB - INTRODUCTION AND OBJECTIVE: Benign paroxysmal positional vertigo is one of the most common vestibular disorders, with a lifetime prevalence of 2.4%. This study aimed to assess age, gender, lesion type and site, association with other vestibular diseases, progression and recurrence in a Portuguese population. METHODS: This was a retrospective observational study of 101 patients diagnosed with benign paroxysmal positional vertigo by the same senior doctor, in a tertiary academic hospital, between January 2009 and May 2011. RESULTS: A total of 101 cases were pooled, with a mean age of 56.57±15.33 years (15-90 years). From these, 72.3% were women. The posterior canal was affected in 72.3%, the lateral in 24.7%, the anterior in 2% and multiple canals in 1%. Unilateral canal and left labyrinth involvement were more frequent. The therapeutic maneuver used most was Epley's. Recurrence was observed in 10.9% of the cases. It was idiopathic in 83.2% of cases. No association was found between the number of maneuvers necessary to treat benign paroxysmal positional vertigo and etiology. CONCLUSION: Benign paroxysmal positional vertigo is more frequent in female subjects, in the 6th decade and involves preferably the posterior semicircular canal of the right labyrinth. In most cases it is idiopathic and treatment with repositioning maneuvers has a mean success of 90%. Our results were in accordance with the literature; nevertheless, in this study the left labyrinth was most affected and the follow-up period was variable. AD - Otorhinolaryngology and Head and Neck Surgery Department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal. Electronic address: claranetosilva@gmail.com. Otorhinolaryngology and Head and Neck Surgery Department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal. AN - 25865125 AU - Silva, C. AU - Amorim, A. M. AU - Paiva, A. DA - Jul-Aug DO - 10.1016/j.otorri.2014.09.003 DP - NLM ET - 2015/04/14 IS - 4 KW - Adolescent Adult Aged Aged, 80 and over Benign Paroxysmal Positional Vertigo/*epidemiology/etiology/therapy Cardiovascular Diseases/epidemiology Craniocerebral Trauma/complications Female Humans Male Meniere Disease/complications Middle Aged Migraine Disorders/complications Patient Positioning/*methods Recurrence Retrospective Studies Risk Factors Semicircular Canals/physiopathology Treatment Outcome Young Adult *Laberinto *Labyrinth *Nistagmo *Nystagmus *Vertigo *Vértigo LA - eng spa N1 - 1988-3013 Silva, Clara Amorim, Ana Margarida Paiva, António Journal Article Observational Study Spain Acta Otorrinolaringol Esp. 2015 Jul-Aug;66(4):205-9. doi: 10.1016/j.otorri.2014.09.003. Epub 2015 Apr 9. PY - 2015 SN - 0001-6519 SP - 205-9 ST - Benign paroxysmal positional vertigo--a review of 101 cases T2 - Acta Otorrinolaringol Esp TI - Benign paroxysmal positional vertigo--a review of 101 cases VL - 66 ID - 3918 ER - TY - JOUR AB - BACKGROUND: Irritable bowel syndrome is a clinical condition presenting pain, distension and abdominal fullness, diarrhea, constipation, and other symptoms. It generates significant impacts on the quality of life of those affected. The pathophysiology is uncertain, but the role of various food types has been established in bowel sensitivity and its clinical manifestations. Carbohydrate intolerance, particularly to lactose, generates similar and sometimes indistinguishable symptoms from irritable bowel syndrome, and in clinical practice is both a frequent and underdiagnosed condition. Carbohydrate intolerance is related to enzymatic deficiencies, alterations of intestinal microbiota and even genetic change. The principal test for a diagnosis of lactose intolerance is the breath test, which measures hydrogen emission (produced only by bacteria), after ingestion of the corresponding substrate. OBJECTIVE: The present work aims to verify the prevalence of lactose intolerance in university students, presenting gastrointestinal symptoms suggestive of irritable bowel syndrome. METHODS: In a transversal study, to screen for those with suggestive symptoms, 124 medicine students participated by responding to a form. Those with abdominal pain were referred for anti-parasite treatment in order to exclude intestinal parasites as a secondary cause. Subsequently, using the hydrogen breath test, bacterial overgrowth was investigated, and if negative, lactose intolerance testing would be performed. Patients presenting high hydrogen concentrations of ≥20 ppm above the basal level were considered lactose intolerant. RESULTS: Of the total of students researched (n=124), 7 were excluded because they did not completing all study phases. From those 117 individuals effectively included in the survey; 8 (6.8%) were diagnosed with lactose intolerance and 2 (1.7%) with bacterial overgrowth. Intolerance was more frequent in; female individuals (75%), age range 18 to 25 years (62.5%), being colored (50%), and in their 5th semester of studies (37.5%). The presence of at least one gastrointestinal symptom among those presenting intolerance (100%), and those not presenting intolerance (42.2%) was found (P=0.002). In addition to abdominal pain (100%) (P<0.001), the most recurrent gastrointestinal symptom in the lactose intolerant students was the distension/flatulence (62.5%) (P=0.026). In relation to life habits and food patterns, there was no statistical difference between lactose tolerant and intolerant individuals, or for symptom frequencies. The more advanced students, completing more periods towards graduation, demonstrated more occurrences of gastrointestinal symptoms, yet without presenting significant statistical discrepancies. CONCLUSION: In view of the test sample quantity (n=21), a high prevalence of lactose intolerance (6.8%) in the academic environment, with epidemiological characteristics compatible to those found the literature is demonstrated, generating knowledge with understanding to prevent, diagnose, alleviate and treat lactose intolerant university students, and generate positive impacts towards well-being, improving the quality of life of these individuals. AD - Faculdade de Medicina da Universidade Federal Do Vale do São Francisco, Paulo Afonso, BA, Brasil. AN - 31633730 AU - Silva, C. J. AU - Leite, I. D. S. AU - Rodrigues, J. W. AU - Almeida, S. P. AU - Nóbrega, B. P. AU - Sampaio Filho, J. D. R. DO - 10.1590/s0004-2803.201900000-57 DP - NLM ET - 2019/10/22 IS - 3 KW - Adolescent Adult Breath Tests Female Humans Irritable Bowel Syndrome/*complications Lactose Intolerance/*epidemiology/etiology Male Middle Aged Quality of Life Students Young Adult LA - eng N1 - 1678-4219 Silva, Cleise de Jesus Orcid: 0000-0001-8456-3721 Leite, Ingrid Dantas Sampaio Orcid: 0000-0002-3550-9937 Rodrigues, José Weberton Orcid: 0000-0003-0859-4854 Almeida, Samara Pereira de Orcid: 0000-0001-6849-3743 Nóbrega, Bruna Pessoa Orcid: 0000-0003-4363-7813 Sampaio Filho, Jarbas Delmoutiez Ramalho Orcid: 0000-0002-3637-3242 Journal Article Brazil Arq Gastroenterol. 2019 Sep 30;56(3):304-311. doi: 10.1590/S0004-2803.201900000-57. eCollection 2019. PY - 2019 SN - 0004-2803 SP - 304-311 ST - ANALYSIS OF LACTOSE INTOLERANCE IN STUDENTS WITH SUGGESTIVE SYMPTOMS OF IRRITABLE BOWEL SYNDROME T2 - Arq Gastroenterol TI - ANALYSIS OF LACTOSE INTOLERANCE IN STUDENTS WITH SUGGESTIVE SYMPTOMS OF IRRITABLE BOWEL SYNDROME VL - 56 ID - 3730 ER - TY - JOUR AB - OBJECTIVE: To quantify and compare direct costs, utilization, and the rate of comorbidities in a sample of patients with fibromyalgia (FM), a poorly understood illness associated with chronic widespread pain that is commonly treated by rheumatologists, to patients with rheumatoid arthritis (RA), a well studied rheumatologic illness associated with inflammatory joint pain. Patients with both illnesses were isolated and reported as a third group. A secondary analysis of work loss was performed for an employed subset of these patients. RESEARCH DESIGN AND METHODS: Retrospective cohort analysis of Thomson Reuters MarketScan administrative healthcare claims and employer-collected absence and disability data for adult patients with a diagnosis of FM (ICD-9-CM 729.1) and/or RA (ICD-9-CM 714.0x,-714.3x) on at least one inpatient or two outpatient claims during 2001-2004. MAIN OUTCOME MEASURES: The 12-month healthcare utilization, expenditures, and rates of comorbidities were quantified for all study-eligible patients; absence and short-term disability days and costs were quantified for an employed subset. RESULTS: The sample included 14034 FM, 7965 RA, and 331 FM+RA patients. Patients with FM had a higher prevalence of several comorbidities and greater emergency department (ED) utilization than those with RA. Mean annual expenditures for FM patients were $10911 (SD=$16075). RA patient annual expenditures were similar to FM: $10716 (SD= $16860). Annual expenditures were almost double in patients with FM+RA ($19395, SD= $25440). A greater proportion of patients with FM had any short-term disability days than those with RA (20 vs. 15%); and a greater proportion of patients with RA had any absence days (65 vs. 80%). Mean costs for absence from work and short-term disability in the FM and RA groups were substantial and similar. The FM+RA group was of insufficient sample size to report on work loss. LIMITATIONS: The availability of newer and more expensive FDA-approved medications since 2004 is not reflected in our findings. This analysis was restricted to commercially insured patients and therefore may not be generalizable to the entire U.S. population. CONCLUSIONS: The burden of illness in FM is substantial and comparable to RA. Patients with FM incurred direct costs approximately equal to RA patients. Patients with FM had more ED, physician, and physical therapy visits than RA patients. Patients in both groups had several comorbidities. Patients with FM+RA incurred direct costs almost double those of the patients with either diagnosis alone. FM and RA patients incurred similar overall absence and short-term disability costs. AD - University of California, Los Angeles, CA, USA. AN - 19220165 AU - Silverman, S. AU - Dukes, E. M. AU - Johnston, S. S. AU - Brandenburg, N. A. AU - Sadosky, A. AU - Huse, D. M. DA - Apr DO - 10.1185/03007990902728456 DP - NLM ET - 2009/02/18 IS - 4 KW - Absenteeism Adolescent Adult Arthritis, Rheumatoid/complications/*economics Cohort Studies Cost of Illness Fibromyalgia/complications/*economics *Health Care Costs Health Services/*economics Humans Middle Aged Predictive Value of Tests Prescription Drugs/economics Retrospective Studies Young Adult LA - eng N1 - 1473-4877 Silverman, Stuart Dukes, Ellen M Johnston, Stephen S Brandenburg, Nancy A Sadosky, Alesia Huse, Dan M Journal Article Research Support, Non-U.S. Gov't England Curr Med Res Opin. 2009 Apr;25(4):829-40. doi: 10.1185/03007990902728456. PY - 2009 SN - 0300-7995 SP - 829-40 ST - The economic burden of fibromyalgia: comparative analysis with rheumatoid arthritis T2 - Curr Med Res Opin TI - The economic burden of fibromyalgia: comparative analysis with rheumatoid arthritis VL - 25 ID - 3408 ER - TY - JOUR AB - The relationship between depression and somatic symptoms such as headache has never been explained. Both depression and headache appear to become more prevalent among women than among men only for cohorts that reach adolescence during periods of great change in opportunities for a female's academic achievement. In Studies 1a and 1b, the same pattern was found to apply to the correlation between depression and headache. In Studies 2a and 2b, self-report measures of depression and headache were found to share significant variance only among female adolescents who reported concerns regarding the limited achievements of their mothers. These females may view the roles of adult women as being limited and may experience stress and low self-esteem associated with depressive and somatic symptomatology. AN - WOS:A1995QF39600003 AU - Silverstein, B. AU - McKoy, E. AU - Clauson, J. AU - Perdue, L. AU - Raben, J. DA - Jan DO - 10.1111/j.1559-1816.1995.tb01582.x IS - 1 N1 - Silverstein, b mckoy, e clauson, j perdue, l raben, j PY - 1995 SN - 0021-9029 SP - 35-48 ST - THE CORRELATION BETWEEN DEPRESSION AND HEADACHE - THE ROLE PLAYED BY GENERATIONAL CHANGES IN FEMALE ACHIEVEMENT T2 - Journal of Applied Social Psychology TI - THE CORRELATION BETWEEN DEPRESSION AND HEADACHE - THE ROLE PLAYED BY GENERATIONAL CHANGES IN FEMALE ACHIEVEMENT UR - ://WOS:A1995QF39600003 VL - 25 ID - 2942 ER - TY - JOUR AB - BACKGROUND: Educating patients on factual information related to chronic pain and self-management improves knowledge, pain outcomes, and compliance. The current study assesses changes in pain knowledge among veterans who attended a 12-week "Pain Education School" and examines whether or not the addition of an active learning component (i.e., use of an audience response system [ARS]) leads to greater increases in pain knowledge. MATERIALS AND METHODS: A sample of 102 veterans 24-84 years of age who elected to participate in the 12-week pain education program was evaluated. Only a subgroup of veterans (n=69) had access to the ARS. RESULTS: A 2×2 repeated-measures multivariate analyses of variance was conducted to examine changes in pain knowledge, pain beliefs, stage of readiness to adopt a self-management approach, and depressive symptoms over time and to explore the impact of ARS use on pain knowledge acquisition. Participants reported a statistically significant difference between their pre- and posttest measures of pain beliefs (p=0.04), stage of readiness to adopt a self-management approach (p=0.00), and depressive symptoms (p=0.00). Veterans who used the ARS demonstrated significantly greater increases in pain knowledge acquisition after completing the pain education program than those who did not (p=0.03). CONCLUSIONS: Findings provide support for the incorporation of ARS in pain education programming to facilitate active learning and to increase knowledge acquisition. Findings also provide evidence for the effectiveness of pain education programs in improving veterans' attitudes about their pain, increasing readiness to engage in self-management, and decreasing depressive symptoms. AD - Jesse Brown VA Medical Center , Chicago, Illinois. AN - 25734588 AU - Simmons, E. B. AU - Cosio, D. AU - Lin, E. H. DA - Jul DO - 10.1089/tmj.2014.0160 DP - NLM ET - 2015/03/04 IS - 7 KW - Adolescent Adult Aged Chronic Pain/*therapy Female *Health Knowledge, Attitudes, Practice Humans Male Middle Aged Patient Education as Topic/*methods Surveys and Questionnaires *Veterans Young Adult behavioral health e-health education military medicine telehealth LA - eng N1 - 1556-3669 Simmons, Elizabeth B Cosio, David Lin, Erica H Evaluation Study Journal Article United States Telemed J E Health. 2015 Jul;21(7):557-63. doi: 10.1089/tmj.2014.0160. Epub 2015 Mar 3. PY - 2015 SN - 1530-5627 SP - 557-63 ST - Using Audience Response Systems to Enhance Chronic, Noncancer Pain Knowledge Acquisition Among Veterans T2 - Telemed J E Health TI - Using Audience Response Systems to Enhance Chronic, Noncancer Pain Knowledge Acquisition Among Veterans VL - 21 ID - 3529 ER - TY - JOUR AB - Objectives Pediatric appendicitis remains a challenging diagnosis in the emergency department (ED). Available risk prediction algorithms may contribute to excessive ED imaging studies. Incorporation of physician gestalt assessment could help refine predictive tools and improve diagnostic imaging decisions. Methods This study was a subanalysis of a parent study that prospectively enrolled patients ages 5 to 20.9 years with a chief complaint of abdominal pain presenting to 11 community EDs within an integrated delivery system between October 1, 2016, and September 30, 2018. Prior to diagnostic imaging, attending emergency physicians enrolled patients with <= 5 days of right-sided or diffuse abdominal pain using a Web-based application embedded in the electronic health record. Predicted risk (gestalt) of acute appendicitis was prospectively entered using a sliding scale from 1% to 100%. As a planned secondary analysis, we assessed the performance of gestalt via c-statistics of receiver operating characteristic (ROC) curves; tested associations between gestalt performance and patient, physician, and facility characteristics; and examined clinical characteristics affecting gestalt estimates. Results Of 3,426 patients, 334 (9.8%) had confirmed appendicitis. Physician gestalt had excellent ROC curve characteristics (c-statistic = 0.83, 95% confidence interval = 0.81 to 0.85), performing particularly well in the low-risk strata (appendicitis rate = 1.1% in gestalt 1%-10% range, negative predictive value of 98.9% for appendicitis diagnosis). Physicians with >= 5 years since medical school graduation demonstrated improved gestalt performance over those with less experience (p = 0.007). All clinical characteristics tested, except pain <24 hours, were significantly associated with physician gestalt value (p < 0.05). Conclusion Physician gestalt for acute appendicitis diagnosis performed well, especially in low-risk patients and when employed by experienced physicians. AN - WOS:000523293200001 AU - Simon, L. E. AU - Kene, M. V. AU - Warton, E. M. AU - Rauchwerger, A. S. AU - Vinson, D. R. AU - Reed, M. E. AU - Chettipally, U. K. AU - Mark, D. G. AU - Sax, D. R. AU - McLachlan, D. I. AU - Cotton, D. M. AU - Lin, J. S. AU - Vazquez-Benitez, G. AU - Kharbanda, A. B. AU - Kharbanda, E. O. AU - Ballard, D. W. DA - Sep DO - 10.1111/acem.13931 IS - 9 N1 - Simon, Laura E. Kene, Mamata, V Warton, E. Margaret Rauchwerger, Adina S. Vinson, David R. Reed, Mary E. Chettipally, Uli K. Mark, Dustin G. Sax, Dana R. McLachlan, D. Ian Cotton, Dale M. Lin, James S. Vazquez-Benitez, Gabriela Kharbanda, Anupam B. Kharbanda, Elyse O. Ballard, Dustin W. Vinson, David R/AAK-3227-2020 Vinson, David R/0000-0001-6559-1858; Rauchwerger, Adina/0000-0002-6329-6836 1553-2712 PY - 2020 SN - 1069-6563 SP - 821-831 ST - Diagnostic Performance of Emergency Physician Gestalt for Predicting Acute Appendicitis in Patients Age 5 to 20 Years T2 - Academic Emergency Medicine TI - Diagnostic Performance of Emergency Physician Gestalt for Predicting Acute Appendicitis in Patients Age 5 to 20 Years UR - ://WOS:000523293200001 VL - 27 ID - 1828 ER - TY - JOUR AB - OBJECTIVES: To further our understanding of social functioning in children with chronic pain, and particularly how social functioning relates to school impairment in this population. METHODS: This study involved 126 adolescents (12 to 17 y) evaluated at a multidisciplinary pain clinic. Adolescents completed measures assessing social functioning, pain, physical limitations, somatic symptoms, and school impairment. RESULTS: Lower social functioning scores were significantly associated with pain, physical limitations, somatic symptoms, and school impairment. Social functioning mediated the relations between adolescents' pain experience (ie, pain, physical symptoms, physical limitations) and school impairment. DISCUSSIONS: These findings highlight the importance of assessing and addressing social functioning in youth with chronic pain. Future research targeting school impairment should include evaluating the potential role that peer difficulties may play. AU - Simons, Laura E. AU - Logan, Deirdre E. AU - Chastain, Laura AU - Stein, Michelle DA - 2010/01// DO - 10.1097/AJP.0b013e3181b511c2 DP - PubMed IS - 1 J2 - Clin J Pain KW - Adolescent Child Chronic Disease Female Humans Male Pain Pain Measurement Social Adjustment Statistics as Topic Students Surveys and Questionnaires LA - eng PY - 2010 SN - 1536-5409 SP - 16-22 ST - The relation of social functioning to school impairment among adolescents with chronic pain T2 - The Clinical Journal of Pain TI - The relation of social functioning to school impairment among adolescents with chronic pain UR - http://www.ncbi.nlm.nih.gov/pubmed/20026948 VL - 26 ID - 106 ER - TY - JOUR AB - IMPORTANCE: Although attachment is associated with sensory modulation among children and adolescents and insecure attachment is associated with pain severity among adolescents, relationships among sensory modulation, attachment, and function have not previously been demonstrated in a clinical sample of children and adolescents with complex persistent pain. OBJECTIVE: To investigate relationships among sensory modulation, attachment, function, and quality of life (QOL) in a pediatric population with persistent pain. DESIGN: Cross-sectional quantitative design. From October 2015 to July 2017, all children, adolescents, and parents attending a clinic for assessment completed questionnaires and were provided information and consent forms. Those who consented completed sensory modulation and attachment questionnaires. SETTING: Tertiary pain management clinic. PARTICIPANTS: Children (ages 8-12 yr) and adolescents (ages 13-18 yr) with persistent pain (pain of >3 mo duration or a specific pain disorder) and the capacity to answer questionnaires independently. MEASURES: Standardized sensory modulation, attachment, pain intensity, functional disability, and QOL questionnaires. Hypotheses were generated before data collection. RESULTS: Of 152 children and adolescents, 114 children (30 girls, 9 boys) and adolescents (68 girls, 7 boys) met study criteria and consented to participate. Hierarchical multiple regression analyses revealed that sensory sensitivity predicted disability for children and adolescents, and attachment anxiety mediated the relationship between low registration and poorer school-related QOL. CONCLUSION AND RELEVANCE: Behaviors related to insecure attachment patterns provide a mediating pathway from sensory modulation to functional disability; addressing such behaviors clinically may facilitate engagement in daily activities for children and adolescents with persistent pain. WHAT THIS ARTICLE ADDS: Results support the need to consider the interactions between sensory modulation and attachment when addressing functional abilities with occupational therapy treatment. AD - Cate Sinclair, B. App Sci. O.T., M. Art Therapy, PhD, is Director, Allied Services, Pain Specialists Australia, Richmond, Victoria, Australia, and Honorary Member, Murdoch Children's Research Institute, Parkville, Victoria, Australia; catherine.sinclair@uq.net.au. Pamela Meredith, PhD, is Head of Occupational Therapy, School of Health, Medical and Applied Sciences, University of Central Queensland, Rockhampton, Queensland, Australia. Jenny Strong, PhD, is Emeritus Professor, School of Health and Rehabilitation, University of Queensland, Brisbane, Queensland, Australia. AN - 32204782 AU - Sinclair, C. AU - Meredith, P. AU - Strong, J. DA - Mar/Apr DO - 10.5014/ajot.2020.033308 DP - NLM ET - 2020/03/25 IS - 2 KW - Adolescent Anxiety/psychology Child Cross-Sectional Studies Female Humans Male *Pain *Quality of Life Surveys and Questionnaires LA - eng N1 - Sinclair, Cate Meredith, Pamela Strong, Jenny Journal Article United States Am J Occup Ther. 2020 Mar/Apr;74(2):7402205040p1-7402205040p11. doi: 10.5014/ajot.2020.033308. PY - 2020 SN - 0272-9490 (Print) 0272-9490 SP - 7402205040p1-7402205040p11 ST - Pediatric Persistent Pain: Associations Among Sensory Modulation, Attachment, Functional Disability, and Quality of Life T2 - Am J Occup Ther TI - Pediatric Persistent Pain: Associations Among Sensory Modulation, Attachment, Functional Disability, and Quality of Life VL - 74 ID - 3628 ER - TY - JOUR AB - OBJECTIVE: To determine whether patients with cluster headache have more sickness absence and disability pension days compared to matched references and possible associations with sociodemographic characteristics. METHODS: We performed a registry study of all patients who had received specialized health care for cluster headache (ICD-10 code G44.0) aged 16-64 years and living in Sweden in 2010 (n = 3,240; 34% women) and matched references from the total population (n = 16,200) regarding their sickness absence and disability pension days in 2010. RESULTS: Mean number of sickness absence days in 2010 was 16.13 (95% confidence interval, 14.05-18.20) among patients with cluster headache and 6.54 (5.97-7.11) among references. When combining sickness absence and disability pension days, patients with cluster headache had 63.15 (58.84-67.45) days, references 34.08 (32.59-35.57) days. Among patients, women had twice as many sickness absence days than men: 23.71 (19.36-28.06) vs 12.41 (10.19-14.63). When adding disability pension days, those numbers were 83.71 (75.57-91.84) vs 52.56 (47.62-57.51). Patients with cluster headache had significantly more sickness absence days in all ages compared to the reference group. Patients with elementary education had more sickness absence/disability pension days (85.88 [75.34-96.42]) compared to those with high school (64.89 [58.82-70.97]) and college/university (41.42 [34.70-48.15]) education. CONCLUSION: This nationwide study shows that patients with cluster headache have significantly more sickness absence and disability pension days compared to matched references. Furthermore, among patients, women had more sickness absence and disability pension days than men. AD - From the Divisions of Neurology (C.S., A.S.) and Insurance Medicine (K.A., P.J.), Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden. christina.sjostrand@ki.se. From the Divisions of Neurology (C.S., A.S.) and Insurance Medicine (K.A., P.J.), Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden. AN - 32024674 AU - Sjöstrand, C. AU - Alexanderson, K. AU - Josefsson, P. AU - Steinberg, A. DA - May 26 DO - 10.1212/wnl.0000000000009016 DP - NLM ET - 2020/02/07 IS - 21 KW - Adolescent Adult Age Factors Case-Control Studies Cluster Headache/*epidemiology *Disability Evaluation Female Humans Male Middle Aged Pensions/*statistics & numerical data Prospective Studies *Registries Risk Factors Sex Factors Sick Leave/*statistics & numerical data Sweden/epidemiology Young Adult LA - eng N1 - 1526-632x Sjöstrand, Christina Alexanderson, Kristina Josefsson, Pontus Steinberg, Anna Journal Article Research Support, Non-U.S. Gov't United States Neurology. 2020 May 26;94(21):e2213-e2221. doi: 10.1212/WNL.0000000000009016. Epub 2020 Feb 5. PY - 2020 SN - 0028-3878 SP - e2213-e2221 ST - Sickness absence and disability pension days in patients with cluster headache and matched references T2 - Neurology TI - Sickness absence and disability pension days in patients with cluster headache and matched references VL - 94 ID - 3819 ER - TY - JOUR AB - BACKGROUND: Chronic pain is a major health problem globally with severe personal and economic consequences. Maternal chronic pain is associated with their children's pain. Family pain models and shared environmental aspects are important in the understanding of chronic pain among adolescents. Pain in itself impairs the quality of life (QoL). However, satisfaction in the aspects of health and functioning, social and economic, psychological, and family life will together constitute a person's subjective experience of QoL. On this background, we considered it important to gain an understanding of the QoL of mothers who have children with chronic pain. We aimed to gain a broader understanding of the QoL in mothers of children with chronic pain and to investigate how they managed their children's pain. METHODS: This study had a qualitative design with face-to-face, in-depth interviews. The concept of QoL was used as a framework for developing a thematic, semi-structured interview guide. Eight mothers of adolescents with chronic pain (two boys and six girls) participated with signed consent. RESULTS: Socio-economic difficulties and health complaints were common. Psychological stress, because of their children's physical pain and other stressful experiences such as bullying, dominated everyday life. Lack of predictability and of responsible involvement from the fathers' side increased the mothers' burden considerably. Experiencing not being helped by others such as health professionals resulted in feelings of helplessness. CONCLUSIONS: These mothers had reduced QoL caused by their own health problems, concern for the child's well-being and lack of social support, which affected the child's upbringing and pain management. By improving these mothers' QoL, family-based shared pain management strategies could help in health promotion, leading to a more positive QoL circle. Elements of family and cognitive therapy could be applied when supporting the mothers and children and improving their QoL. AD - Faculty of Health and Science, Oslo Metropolitan University, Postboks 4, St. Olavs plass, 0130, Oslo, Norway. siv.skarstein@oslomet.no. Faculty of Health and Science, Oslo Metropolitan University, Postboks 4, St. Olavs plass, 0130, Oslo, Norway. AN - 32546203 AU - Skarstein, S. AU - Bergem, A. K. AU - Helseth, S. C2 - PMC7298795 DA - Jun 16 DO - 10.1186/s40359-020-00430-4 DP - NLM ET - 2020/06/18 IS - 1 KW - Adolescent Adult *Child Welfare *Chronic Pain Fathers Female Humans Interviews as Topic Male Mothers/*psychology Pain Management *Quality of Life Stress, Psychological/etiology Adolescents Chronic pain Mothers Non-prescript pain medicine Over-the-counter analgesics Quality of life declare that they have no competing interests. LA - eng N1 - 2050-7283 Skarstein, S Orcid: 0000-0003-2856-3801 Bergem, A K Helseth, S Journal Article BMC Psychol. 2020 Jun 16;8(1):64. doi: 10.1186/s40359-020-00430-4. PY - 2020 SN - 2050-7283 SP - 64 ST - How do mothers of adolescents with chronic pain experience their own quality of life? T2 - BMC Psychol TI - How do mothers of adolescents with chronic pain experience their own quality of life? VL - 8 ID - 3013 ER - TY - JOUR AB - BACKGROUND: Being bullied and socially excluded interferes with the fundamental need for humans to belong to a social group, which is necessary for well-being. This might underpin pain and the use of non-prescription analgesics. AIM: The aim of the study was to gain insight into how social exclusion and bullying affect well-being in adolescents reporting frequent pain and high use of non-prescription analgesics. METHODS: A phenomenological hermeneutical method based on in-depth interviews was used. Nineteen teenagers, 14-16 years of age voluntarily participated in the study. Those included had frequent pain and used non-prescription analgesics daily or several times a week. RESULTS: Bullying and social exclusion affects thoughts, feelings and attitudes and thereby the quality of life of the adolescents we interviewed. They described feelings such as sadness, loneliness and depression, and a sense of being an outsider among peers was common. It also appears that bullying has significant potential to spread in a school environment. CONCLUSION: The adolescents were self-aware and well-articulated. They conceptualised their experiences of being socially excluded and bullied. They described being socially excluded and bullied by peers as painful and they used non-prescription analgesics to alleviate pain. Teachers and health professionals should be aware of frequent pain and high use of non-prescribed analgesic medication as signs of psychosocial stress caused by social exclusion and bullying. Social exclusion and bullying should be systematically mapped, and targeted interventions implemented. AD - Faculty of Health and Science, Oslo Metropolitan University, St. Olavs Plass, P.O. Box 4, 0130, Oslo, Norway. siv.skarstein@oslomet.no. Faculty of Health and Science, Oslo Metropolitan University, St. Olavs Plass, P.O. Box 4, 0130, Oslo, Norway. AN - 33115532 AU - Skarstein, S. AU - Helseth, S. AU - Kvarme, L. G. C2 - PMC7592354 declare that they have no competing interests. DA - Oct 28 DO - 10.1186/s40359-020-00478-2 DP - NLM ET - 2020/10/30 IS - 1 KW - Adolescent Analgesics/*administration & dosage/*therapeutic use Bullying/*psychology Female Humans Male *Pain Pain Management/*statistics & numerical data *Psychological Distance *Qualitative Research Quality of Life LA - eng N1 - 2050-7283 Skarstein, Siv Orcid: 0000-0003-2856-3801 Helseth, Sølvi Kvarme, Lisbeth Gravdal Journal Article BMC Psychol. 2020 Oct 28;8(1):112. doi: 10.1186/s40359-020-00478-2. PY - 2020 SN - 2050-7283 SP - 112 ST - It hurts inside: a qualitative study investigating social exclusion and bullying among adolescents reporting frequent pain and high use of non-prescription analgesics T2 - BMC Psychol TI - It hurts inside: a qualitative study investigating social exclusion and bullying among adolescents reporting frequent pain and high use of non-prescription analgesics VL - 8 ID - 3575 ER - TY - JOUR AB - Background: Use of over-the-counter analgesics among adolescents has increased markedly. High consumption of over-the-counter analgesics among adolescents is associated with frequent pain, lower self-esteem, reduced sleep, lower educational ambition, binge drinking, higher caffeine consumption, and part-time employment. Knowledge about life experiences of adolescents who frequently use over-the-counter analgesics may be useful to prevent health problems. The purpose of the study was to increase knowledge about adolescents who suffer from frequent pain and have a high consumption of over-the-counter analgesics. Methods: A qualitative study, employing one-on-one, in-depth interviews using a thematic interview guide. Data were collected in Norway in 2013-2014. Three boys and sixteen girls; aged 14-16 years, who continuously consumed over-the-counter analgesics were recruited from ten high schools in urban and suburban districts. Candidate participants were excluded if they were medically diagnosed with an acute or chronic illness, requiring extended use of over-the-counter analgesics within the last year. The interviews were taped, transcribed and analysed as text according to Kvale's three contexts of interpretation: self-understanding, common sense and theory. Results: All participants disclosed unresolved physical and psychosocial distress characterized as pain. Frequent pain from various body parts made everyday life challenging. Methods of pain self-appraisal and over-the-counter analgesics use often mimicked maternal patterns. Participants reported being raised under unpredictable circumstances that contributed to long lasting family conflicts and peer-group problems. Participants wanted to feel appreciated and to be socially and academically successful. However, pain reduced their ability to manage everyday life, hampered experienced possibilities for success, and made social settings difficult. Conclusions: Childhood experiences influence how adolescents experience pain and use over-the-counter analgesics. Coping with difficult situations or attempting to mask symptoms with over-the-counter analgesics can perpetuate and amplify underlying problems. High consumption of over-the-counter analgesics and frequent pain may be warning signs of adolescents with possible health threatening conditions and reduced quality of life. These adolescent might be in need of support from school nurses and General Practitioners. This study identifies new perspectives that may lead to novel approaches to identify, guide, and support adolescents with frequent pain and high consumption of over-the-counter analgesics. AN - WOS:000377516100001 AU - Skarstein, S. AU - Lagerlov, P. AU - Kvarme, L. G. AU - Helseth, S. C7 - 16 DA - Mar DO - 10.1186/s12912-016-0135-9 N1 - Skarstein, Siv Lagerlov, Per Kvarme, Lisbeth Gravdal Helseth, Solvi Skarstein, Siv/0000-0003-2856-3801 PY - 2016 SN - 1472-6955 ST - High use of over-the-counter analgesic; possible warnings of reduced quality of life in adolescents - a qualitative study T2 - Bmc Nursing TI - High use of over-the-counter analgesic; possible warnings of reduced quality of life in adolescents - a qualitative study UR - ://WOS:000377516100001 VL - 15 ID - 2179 ER - TY - JOUR AB - Aims and objectivesThis study aims to describe conditions that may influence the development of identity in adolescents frequently using over-the-counter analgesics. BackgroundFrequent self-medication with analgesics among adolescents is associated with several physical pain points, low self-esteem and low ambitions for the future. Continuous use of over-the-counter analgesics can keep adolescents from learning healthier coping strategies. DesignQualitative individual interviews with adolescents and their mothers were conducted and transcribed. Furthermore, they were analysed as dyads. Setting and participantsStudents aged 14-16years in 9th and 10th grades in 10 Norwegian junior high schools self-reporting at least weekly use of analgesics were asked to participate. Those who wanted to take part took a consent letter to their parents, also inviting the parent to participate. ResultsSix girls, two boys and their mothers were included. The teenagers were highly dependent on their mothers. They had often been bullied, lacked good relationships with peers, avoided conflicts and strived to be accepted. Their mothers felt solely responsible for their upbringing and showed great concern for all the pain experienced by their child. A close relationship between mother and child influenced how the adolescent managed their pain, including their use of over-the-counter analgesics. Three main themes were identified in the stories of mother and child: Vulnerable adolescents, Mother knows best and Pain is a shared project. ConclusionsPain among adolescents may be amplified by a difficult family situation and insecure relationships with peers. Strategies within the family may sustain pain as a shared project keeping the adolescent and main caregiver close together, and this might be hampering identity development. To help adolescents with pain and high consumption of over-the-counter analgesics, the adolescents' relationship with parents must be considered in designing an intervention. Guidance on pain assessment, pain management, including appropriate use of over-the-counter analgesics, should be included. AN - WOS:000444077000016 AU - Skarstein, S. AU - Lagerlov, P. AU - Kvarme, L. G. AU - Helseth, S. DA - Oct DO - 10.1111/jocn.14513 IS - 19-20 N1 - Skarstein, Siv Lagerlov, Per Kvarme, Lisbeth Gravdal Helseth, Solvi Skarstein, Siv/0000-0003-2856-3801 1365-2702 PY - 2018 SN - 0962-1067 SP - 3583-3591 ST - Pain and development of identity in adolescents who frequently use over-the-counter analgesics: A qualitative study T2 - Journal of Clinical Nursing TI - Pain and development of identity in adolescents who frequently use over-the-counter analgesics: A qualitative study UR - ://WOS:000444077000016 VL - 27 ID - 1993 ER - TY - JOUR AB - Seven pediatric patients (aged 11-16 years) with chronic abdominal wall pain are presented who gained significant relief from a rectus sheath block (RSB). We describe the case histories and review the relevant literature for this technique. The etiology of the abdominal wall pain was considered to be abdominal cutaneous nerve entrapment, iatrogenic peripheral nerve injury, myofascial pain syndrome or was unknown. All patients showed significant initial improvement in pain and quality of life. Three patients required only the RSB to enable them to be pain-free and return to normal schooling and physical activities. Two children received complete relief for more than 1 year. In the majority of cases, the procedure was carried out under general anesthesia as a daycase procedure. Local anesthetic and steroids were used. This is the first report of the successful use of this technique in the chronic pain management setting in children. AN - WOS:000250648300013 AU - Skinner, A. V. AU - Lauder, G. R. DA - Dec DO - 10.1111/j.1460-9592.2007.02345.x IS - 12 N1 - Skinner, Adam V. Lauder, Gillian R. Lauder, Gillian/0000-0001-6774-6120 1460-9592 PY - 2007 SN - 1155-5645 SP - 1203-1211 ST - Rectus sheath block: successful use in the chronic pain management of pediatric abdominal wall pain T2 - Pediatric Anesthesia TI - Rectus sheath block: successful use in the chronic pain management of pediatric abdominal wall pain UR - ://WOS:000250648300013 VL - 17 ID - 2675 ER - TY - JOUR AB - STUDY DESIGN: Cross-sectional sample with longitudinal information. OBJECTIVE: To estimate the relationship between the occurrence of low back pain (LBP) and various types of school furniture and anthropometric dimensions in schoolchildren, and physical loading by school bag carrying. SUMMARY OF BACKGROUND DATA: Some types of school furniture may be hypothesized to prevent or cause LBP. Despite strong opinions in the public debate about a possible relationship between use of various types of school furniture and LBP, scientific research on this matter is sparse. METHODS: Five hundred forty-six schoolchildren aged 14 to 17 years answered a questionnaire about sitting positions during school hours and the presence and severity of LBP. Furthermore, the anthropometric dimensions and the weight of the school bags were measured. The types and dimensions of the school furniture were described and measured. In multivariate analyses was adjusted for physical activity and other possible risk factors. RESULTS: More than half of the adolescents experienced LBP during the preceding 3 months, and 24.2% reported reduced daily function or care seeking because of LBP. LBP occurrence was not associated with the types or dimensions of the school furniture or body dimensions, but was positively associated with carrying the school bag on 1 shoulder [OR: 2.06 (1.29-3.31)]. CONCLUSION: The present study does not support the hypothesis of different types of school furniture being a causative or preventing factor for LBP. Carrying the school bag in an asymmetric manner may play a role. AU - Skoffer, Birgit DA - 2007/11/15/ DO - 10.1097/BRS.0b013e31815a5a44 DP - PubMed IS - 24 J2 - Spine (Phila Pa 1976) KW - Activities of Daily Living Adaptation, Psychological Adolescent Anthropometry Cross-Sectional Studies Ergonomics Female Humans Interior Design and Furnishings Lifting Logistic Models Low Back Pain Male Motor Activity Multivariate Analysis Posture Risk Factors Schools Weight-Bearing LA - eng PY - 2007 SN - 1528-1159 SP - E713-717 ST - Low back pain in 15- to 16-year-old children in relation to school furniture and carrying of the school bag T2 - Spine TI - Low back pain in 15- to 16-year-old children in relation to school furniture and carrying of the school bag UR - http://www.ncbi.nlm.nih.gov/pubmed/18007232 VL - 32 ID - 114 ER - TY - BOOK A2 - Wells, J. C. D. AB - Background and aims: The inpatient Pediatric Pain Rehabilitation Program at the Kennedy Krieger Institute, Baltimore, MD, USA approaches chronic pain using a biopsychosocial rehabilitation model. Behavioral and cognitive behavioral procedures are integrated into a coordinated interdisciplinary treatment protocol. The interdisciplinary team collaborates to address physical, educational and social deficits resulting from activity avoidance and deconditioning. It teaches and reinforces child coping, self-management and wellness behavior while avoiding reinforcement of anxiety, distress, helplessness and illness behavior. Therapy activities are task analyzed into short-term objectives that are measured, and their attainment positively reinforced. Parent training, individual, and family therapy are provided as well as consultation for family, school, and community re-integration. In 2008 we conducted a retrospective review of 41consecutive patients (8-21 years of age) who were treated in our program in order to assess their school attendance, sleep, medication usage, functional disability, physical mobility, and pain ratings [1]. As a group, significant improvements were observed in these clinical outcomes. These results provided preliminary support for the efficacy of our inpatient interdisciplinary behavioral rehabilitation approach to the treatment of pediatric pain-associated disability. Methods: Retrospective data analysis of 70 pediatric patients with chronic pain treated in our program. Results: Updated outcome data for our cumulative sample of patients are presented along with post-discharge follow-up data from the sample for which these measures are available. Conclusion: The results appear to provide additional support for the efficacy of our inpatient interdisciplinary behavioral rehabilitation approach to the treatment of pediatric pain-associated disability. However, experimentally controlled clinical trials of our protocol are needed to definitively establish it as an empirically supported treatment for pediatric pain associated disability. AN - WOS:000321893400025 AU - Slifer, K. J. AU - Ward, C. M. AU - Amari, A. AU - Bierenbaum, M. AU - McLean, H. AU - Pidcock, F. AU - Kost-Byerly, S. N1 - Slifer, K. J. Ward, C. M. Amari, A. Bierenbaum, M. McLean, H. Pidcock, F. Kost-Byerly, S. Wspc 2012 15th World Congress of Pain Clinicians Jun 27-30, 2012 World Soc Pain Clinicians (WSPC), Granada, SPAIN PY - 2012 SN - 978-88-7587-665-4 SP - 113-115 ST - Interdisciplinary Behavioral Rehabilitation of Pediatric Pain-associated Disability T2 - 15th World Congress of Pain Clinicians TI - Interdisciplinary Behavioral Rehabilitation of Pediatric Pain-associated Disability UR - ://WOS:000321893400025 ID - 2451 ER - TY - JOUR AB - OBJECTIVE: To show whether a difference in fine motor control exists between patients with chronic, undiagnosed wrist pain (CUWP) and healthy controls. Furthermore, a method to assess fine motor function of the wrist is evaluated. DESIGN: A case-control study. SETTING: The Academic Medical Center in Amsterdam, the Netherlands. SUBJECTS: Twenty-seven CUWP patients were compared with 50 healthy control subjects. INTERVENTIONS: Subjects performed horizontal stroke patterns on a digital writing tablet connected to a computer. The control subjects were tested twice to obtain test-retest reliability. A visual analogue scale was used to assess subjective pain. MAIN OUTCOME MEASURES: Fluency of movement and average velocity were measured. Intraclass correlation, ANOVA repeated measures statistics and Pearson correlation were calculated. RESULTS: There is a significant difference in fluency of motion between patients and controls, possibly due to a disturbed motor control, since there is no relationship between pain and test score, nor do CUWP patients have any abnormality in the wrist that can explain the disturbance in motor function. The test method is reliable (ICC = 0.78) and valid. CONCLUSIONS: The disturbed fine motor control in CUWP patients is suggested to maintain chronic wrist pain through 'strain injury, causing' pain evasive adaptation of the motor control system. This might lead to new perspectives regarding treatment of CUWP patients. AD - Department of Plastic, Reconstructive and Hand Surgery, Academic Medical Center, Amsterdam, The Netherlands. AN - 11330758 AU - Smeulders, M. J. AU - Kreulen, M. AU - Bos, K. E. DA - Apr DO - 10.1191/026921501672958566 DP - NLM ET - 2001/05/02 IS - 2 KW - Adaptation, Physiological Adolescent Adult Analysis of Variance Attention Case-Control Studies Chronic Disease Diagnosis, Computer-Assisted/*methods/standards Female Functional Laterality Humans Male Middle Aged *Motor Skills Pain/*diagnosis/*physiopathology Pain Measurement Physical Examination/*methods/standards Range of Motion, Articular *Wrist LA - eng N1 - Smeulders, M J Kreulen, M Bos, K E Journal Article Research Support, Non-U.S. Gov't Validation Study England Clin Rehabil. 2001 Apr;15(2):133-41. doi: 10.1191/026921501672958566. PY - 2001 SN - 0269-2155 (Print) 0269-2155 SP - 133-41 ST - Fine motor assessment in chronic wrist pain: the role of adapted motor control T2 - Clin Rehabil TI - Fine motor assessment in chronic wrist pain: the role of adapted motor control VL - 15 ID - 3666 ER - TY - JOUR AB - Study Objective: Enhanced recovery after surgery (ERAS) protocols have been successfully implemented in adult gynecology as well as adult and pediatric colorectal and urologic surgery with reduction in narcotic use, complications, return to the system (RTS), length of stay (LOS), and improved patient satisfaction. There are no studies evaluating the use of ERAS in pediatric and adolescent gynecology (PAG). The goals of this study are to present initial patient outcomes using ERAS in PAG patients undergoing intra-abdominal gynecologic surgery to prove efficacy, patient satisfaction, and decreased narcotic use. Design: As a quality improvement measure in perioperative care, an ERAS protocol including preoperative, intraoperative, and post-operative components and a follow-up patient telephone call for pain assessment was implemented for all intra-abdominal gynecologic procedures. A retrospective study on implementation of ERAS components, outcomes, and patient satisfaction was then performed in participants meeting inclusion criteria. Setting: Large academic children's hospital. Participants: Patients !25 years of age who underwent laparoscopic (LSC) or open abdominal (XLAP) gynecologic surgery using an ERAS protocol by the PAG service over a 12-month period. Interventions: An ERAS protocol including preoperative, intraoperative, and postoperative components and follow-up patient telephone call for pain assessment was implemented for all major gynecologic surgeries performed by the PAG service. Main Outcome Measures: Patient satisfaction with the perioperative ERAS protocol along with components including pain management, narcotic use, LOS, RTS, and postoperative complications for various intra-abdominal gynecologic procedures. Results: A total of 40 participants met inclusion criteria for the study. Thirty-four (85%) participants underwent LSC procedures and six (15%) underwent XLAP. Of the LSC patients, 95% were discharged on postoperative day 0, and all XLAP patients and one LSC patient were discharged on postoperative day 1. In all, 95% of patients were discharged from the hospital requiring only non-narcotic ERAS medications. There were no readmissions or postoperative complications. All patients were satisfied with their postoperative pain control at their follow-up telephone call and clinic visit. Conclusion: Implementation of a pediatric-specific ERAS protocol in children and adolescents undergoing gynecologic surgery is feasible and safe, and leads to less narcotic use without an increase in complications or decrease in patient satisfaction. AN - WOS:000560474000016 AU - Smith, A. E. AU - Heiss, K. AU - Childress, K. J. DA - Aug DO - 10.1016/j.jpag.2020.02.001 IS - 4 N1 - Smith, Abigail E. Heiss, Kurt Childress, Krista J. American-College-of-Surgeons (ACS) Quality and Safety Conference Jul 19-22, 2019 Washington, DC Amer Coll Surg 1873-4332 PY - 2020 SN - 1083-3188 SP - 403-409 ST - Enhanced Recovery After Surgery in Pediatric and Adolescent Gynecology: A Pilot Study T2 - Journal of Pediatric and Adolescent Gynecology TI - Enhanced Recovery After Surgery in Pediatric and Adolescent Gynecology: A Pilot Study UR - ://WOS:000560474000016 VL - 33 ID - 1805 ER - TY - JOUR AB - BACKGROUND: Elite-level women's fastpitch softball players place substantial biomechanical strains on the elbow that can result in medial elbow pain and ulnar neuropathic symptoms. There is scant literature reporting the expected outcomes of the treatment of these injuries. This study examined the results of treatment in a series of these patients. METHODS: We identified 6 female softball pitchers (4 high school and 2 collegiate) with medial elbow pain and ulnar neuropathic symptoms. Trials of conservative care failed in all 6, and they underwent surgical treatment with subcutaneous ulnar nerve transposition. These patients were subsequently monitored postoperatively to determine outcome. RESULTS: All 6 female pitchers had early resolution of elbow pain and neuropathic symptoms after surgical treatment. Long-term follow-up demonstrated that 1 patient quit playing softball because of other injuries but no longer reported elbow pain or paresthesias. One player was able to return to pitching at the high school level but had recurrent forearm pain and neuritis 1 year later while playing a different sport and subsequently stopped playing competitive sports. Four patients continued to play at the collegiate level without further symptoms. CONCLUSIONS: Medial elbow pain in women's softball pitchers caused by ulnar neuropathy can be treated effectively with subcutaneous ulnar nerve transposition if nonsurgical options fail. Further study is necessary to examine the role of overuse, proper training techniques, and whether pitching limits may be necessary to avoid these injuries. AD - West Tennessee Bone and Joint Clinic, Jackson, TN, USA. Electronic address: amsmith.md@gmail.com. West Tennessee Bone and Joint Clinic, Jackson, TN, USA. AN - 28964676 AU - Smith, A. M. AU - Butler, T. H. th AU - Dolan, M. S. DA - Dec DO - 10.1016/j.jse.2017.08.013 DP - NLM ET - 2017/10/02 IS - 12 KW - Adolescent Baseball/*injuries Biomechanical Phenomena Elbow Female Humans Neuralgia/etiology/*surgery Retrospective Studies Return to Sport Ulnar Nerve/*injuries/surgery Ulnar Neuropathies/etiology/*surgery Young Adult Ulnar neuropathy medial elbow pain pitcher softball ulnar nerve subluxation ulnar neuritis windmill LA - eng N1 - 1532-6500 Smith, Adam M Butler, Thomas H 4th Dolan, Michael S Journal Article United States J Shoulder Elbow Surg. 2017 Dec;26(12):2220-2225. doi: 10.1016/j.jse.2017.08.013. Epub 2017 Sep 28. PY - 2017 SN - 1058-2746 SP - 2220-2225 ST - Ulnar neuropathy and medial elbow pain in women's fastpitch softball pitchers: a report of 6 cases T2 - J Shoulder Elbow Surg TI - Ulnar neuropathy and medial elbow pain in women's fastpitch softball pitchers: a report of 6 cases VL - 26 ID - 3576 ER - TY - JOUR AB - Introduction: Cancer for adolescents and young adults (AYA) differs from younger and older patients; AYA face medical challenges while navigating social and developmental transitions. Research suggests that these patients are under or inadequately served by current support services, which may affect health-related quality of life (HRQOL). Methods:We examined unmet service needs and HRQOL in the National Cancer Institute's Adolescent and Young Adult Health Outcomes and Patient Experience (AYA HOPE) study, a population-based cohort (n=484), age 15-39, diagnosed with cancer 6-14 months prior, in 2007-2009. Unmet service needs were psychosocial, physical, spiritual, and financial services where respondents endorsed that they needed, but did not receive, a listed service. Linear regression models tested associations between any or specific unmet service needs and HRQOL, adjusting for demographic, medical, and health insurance variables. Results: Over one-third of respondents reported at least one unmet service need. The most common were financial (16%), mental health (15%), and support group (14%) services. Adjusted models showed that having any unmet service need was associated with worse overall HRQOL, fatigue, physical, emotional, social, and school/work functioning, and mental health (p's < 0.0001). Specific unmet services were related to particular outcomes [e.g., needing pain management was associated with worse overall HRQOL, physical and social functioning (p's < 0.001)]. Needing mental health services had the strongest associations with worse HRQOL outcomes; needing physical/occupational therapy was most consistently associated with poorer functioning across domains. Discussion: Unmet service needs in AYAs recently diagnosed with cancer are associated with worse HROOL. Research should examine developmentally appropriate, relevant practices to improve access to services demonstrated to adversely impact HRQOL, particularly physical therapy and mental health services. AN - WOS:000218338900042 AU - Smith, A. W. AU - Parsons, H. M. AU - Kent, E. E. AU - Bellizzi, K. AU - Zebrack, B. J. AU - Keel, G. AU - Lynch, C. F. AU - Rubenstein, M. B. AU - Keegan, T. H. M. AU - Grp, Aya Hope Study Collaborative C7 - 75 DO - 10.3389/fonc.2013.00075 N1 - Smith, Ashley Wilder Parsons, Helen M. Kent, Erin E. Bellizzi, Keith Zebrack, Brad J. Keel, Gretchen Lynch, Charles F. Rubenstein, Mara B. Keegan, Theresa H. M. Kent, Erin/B-8585-2018 Kent, Erin/0000-0003-2503-2191 PY - 2013 SN - 2234-943X ST - Unmet support service needs and health-related quality of life among adolescents and young adults with cancer: the AYA HOPE study T2 - Frontiers in Oncology TI - Unmet support service needs and health-related quality of life among adolescents and young adults with cancer: the AYA HOPE study UR - ://WOS:000218338900042 VL - 3 ID - 2399 ER - TY - JOUR AB - This article is concerned with the efforts used by Black male adoptive children to cope with systemic White racial oppression when raised by White adoptive families, specifically the emotional labor expended through the use of cool pose. Drawing from theoretical concepts and frameworks from the social and behavior sciences, this article analyzes the "cool" element as a protective factor and posits this phenomenon is more than esthetic, but instead a fundamental aspect of Black male survival no matter the context. The central aim of this paper is to provide information to White adoptive parents, social workers, psychologist, academics, and other childcare advocates or professionals with cognitive tools to understand the behavior of Black male adoptees, as they search for meaning in their lives and find ways to manage the pain and frustration they often hide deep beneath the skin. AN - WOS:000436690300004 AU - Smith, D. T. DO - 10.1179/1053078915z.00000000026 IS - 2 N1 - Smith, Darron T. 1573-658x Si PY - 2015 SN - 1053-0789 SP - 93-108 ST - The emotional labor of playing cool: How Black male transracial adoptees find ways to cope within predominately White settings T2 - Journal of Social Distress and the Homeless TI - The emotional labor of playing cool: How Black male transracial adoptees find ways to cope within predominately White settings UR - ://WOS:000436690300004 VL - 24 ID - 2268 ER - TY - JOUR AB - STUDY OBJECTIVE: To inform the development of interventions that could improve patient engagement around the risks and benefits of alternative approaches to pain management in the emergency department (ED), we seek to capture the perspectives and experiences of patients treated for pain in this setting. METHODS: Three trained interviewers conducted semistructured open-ended telephone interviews with patients discharged from a single urban academic ED after presenting with acute pain related to fracture, renal colic, or musculoskeletal back injury. We recruited subjects until achieving thematic saturation according to periodic review of the interview transcripts. Interviews were audio recorded, professionally transcribed, and uploaded into QSR NVivo (version 10.0) for coding and analysis using modified grounded theory. An interdisciplinary team double coded the data and convened to review emerging themes, ensure interrater reliability, and establish consensus on discrepancies. RESULTS: We had 23 completed subject interviews, the majority of which were women. Interrater reliability for coding exceeded 90%. The major themes elicited centered on domains of patient awareness of the potential for opioid dependence and patient-provider communication relating to pain management. From the patient perspective, emergency physicians typically do not present alternative pain management options or discuss the risks of opioid dependence. Patients with negative experiences related to pain management describe deficiencies in patient-provider communication leading to misunderstanding of clinical diagnoses, fragmentation of care among their health care providers, and a desire to be involved in the decisionmaking process around their pain management. Patients with positive experiences commented on regular communication with their care team, rapid pain management, and the empathetic nature of their care providers. Patients communicate fears about the risks of opioid addiction, beliefs that following a prescribed opioid regimen is protective of developing opioid dependence, and an understanding of the broader tensions that providers face relating to the prescription of opioid therapy. CONCLUSION: Patients identified a deficit of communication around opioid risk and pain management options in the ED. AD - Center for Emergency Care Policy & Research, Department of Emergency Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA. Center for Emergency Care Policy & Research, Department of Emergency Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA. Center for Emergency Care Policy & Research, Department of Emergency Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Division of Medical Toxicology, Department of Emergency Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA. Center for Emergency Care Policy & Research, Department of Emergency Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA. Electronic address: zfm@upenn.edu. AN - 25865093 AU - Smith, R. J. AU - Rhodes, K. AU - Paciotti, B. AU - Kelly, S. AU - Perrone, J. AU - Meisel, Z. F. DA - Sep DO - 10.1016/j.annemergmed.2015.03.025 DP - NLM ET - 2015/04/14 IS - 3 KW - Acute Pain/*drug therapy Adolescent Adult Aged Communication Decision Making Emergency Service, Hospital Female Grounded Theory Humans Interviews as Topic Male Middle Aged Opioid-Related Disorders/etiology/prevention & control Pain Management/adverse effects/*methods Patient Participation/psychology Young Adult LA - eng N1 - 1097-6760 Smith, Robert J Rhodes, Karin Paciotti, Breah Kelly, Sheila Perrone, Jeanmarie Meisel, Zachary F Journal Article Research Support, Non-U.S. Gov't United States Ann Emerg Med. 2015 Sep;66(3):246-252.e1. doi: 10.1016/j.annemergmed.2015.03.025. Epub 2015 Apr 9. PY - 2015 SN - 0196-0644 SP - 246-252.e1 ST - Patient Perspectives of Acute Pain Management in the Era of the Opioid Epidemic T2 - Ann Emerg Med TI - Patient Perspectives of Acute Pain Management in the Era of the Opioid Epidemic VL - 66 ID - 3661 ER - TY - JOUR AB - This review seeks to provide a current overview of musculoskeletal pain in overweight and obese children. Databases searched were Academic Search Complete, CINAHL, Medline, Proquest Health and Medical Complete, Scopus, Google Scholar, SPORTDiscuss and Trove for studies published between 1 January 2000 and 30 December 2012. We used a broad definition of children within a 3- to 18-year age range. The search strategy included the following terms: obesity, morbid obesity, overweight, pain, musculoskeletal pain, child, adolescent, chronic pain, back pain, lower back pain, knee pain, hip pain, foot pain and pelvic pain. Two authors independently assessed each record, and any disagreement was resolved by the third author. Data were analysed using a narrative thematic approach owing to the heterogeneity of reported outcome measures. Ninety-seven records were initially identified using a variety of terms associated with children, obesity and musculoskeletal pain. Ten studies were included for thematic analysis when predetermined inclusion criteria were applied. Bone deformity and dysfunction, pain reporting and the impact of children being overweight or obese on physical activity, exercise and quality of life were the three themes identified from the literature. Chronic pain, obesity and a reduction in physical functioning and activity may contribute to a cycle of weight gain that affects a child's quality of life. Future studies are required to examine the sequela of overweight and obese children experiencing chronic musculoskeletal pain. AD - 1] Family and Community Health Research Group, School of Nursing and Midwifery, University of Western Sydney, Campbelltown, NSW, Australia [2] Centre for Pharmacology and Therapeutics, Imperial College, Chelsea and Westminster Campus, London, UK. Family and Community Health Research Group, School of Nursing and Midwifery, University of Western Sydney, Campbelltown, NSW, Australia. AN - 24077005 AU - Smith, S. M. AU - Sumar, B. AU - Dixon, K. A. C2 - PMC3884137 DA - Jan DO - 10.1038/ijo.2013.187 DP - NLM ET - 2013/10/01 IS - 1 KW - Activities of Daily Living Adolescent Child Child, Preschool Diet Female Humans Male *Motor Activity Musculoskeletal Pain/*epidemiology/*etiology/prevention & control Pediatric Obesity/*complications/*epidemiology/prevention & control *Quality of Life LA - eng N1 - 1476-5497 Smith, S M Sumar, B Dixon, K A Journal Article Review Int J Obes (Lond). 2014 Jan;38(1):11-5. doi: 10.1038/ijo.2013.187. Epub 2013 Sep 30. PY - 2014 SN - 0307-0565 (Print) 0307-0565 SP - 11-5 ST - Musculoskeletal pain in overweight and obese children T2 - Int J Obes (Lond) TI - Musculoskeletal pain in overweight and obese children VL - 38 ID - 3843 ER - TY - JOUR AB - BACKGROUND: Migraine is associated with significant negative impact, including reduced quality of life, impaired functioning, and comorbid psychiatric disorders. However, the impact of migraine on university students is understudied, despite their high prevalence of migraine and psychiatric disorders and their frequent use in research studies. OBJECTIVES: The aim of this cross-sectional study was to evaluate the impact of migraine among college students on quality of life, functional impairment, and comorbid psychiatric symptoms. METHODS: Three hundred and ninety-one students (76.73% female, mean age = 19.43 ± 2.80 years) completed well-validated measures of migraine and migraine-related disability, quality of life, and comorbid psychiatric symptoms. They also quantified impairment in school attendance and home functioning and reported the number of medical visits during the preceding 3 months. RESULTS: One hundred and one (25.83%) met conservative screening criteria for episodic migraine; their mean score on the Migraine Disability Assessment Questionnaire was 9.98 ± 12.10. Compared to those not screening positive for migraine, the migraine-positive group reported reduced quality of life on 5 of 6 domains, as well as a higher frequency of missed school days (2.74 vs 1.36), impaired functioning at home (2.84 vs 1.21 days), and medical visits (1.86 vs 0.95). They also reported more symptoms of both depression and anxiety than controls, although differences in functional impairment remained after controlling for these comorbid psychiatric symptoms. These differences were highly statistically significant and corroborated by evidence of clinically significant impairment; the corresponding effect sizes were modest but non-trivial. CONCLUSIONS: Episodic migraine is associated with negative impact in numerous domains among university students. These findings replicate and extend those of studies on other samples and have implications for future research studies with this population. AD - Department of Psychology, University of Mississippi, Oxford, MS, USA. AN - 21457242 AU - Smitherman, T. A. AU - McDermott, M. J. AU - Buchanan, E. M. DA - Apr DO - 10.1111/j.1526-4610.2011.01857.x DP - NLM ET - 2011/04/05 IS - 4 KW - Adolescent Adult Comorbidity Cross-Sectional Studies Female Health Surveys/methods Humans Male Mental Disorders/*epidemiology/*psychology Middle Aged Migraine Disorders/*epidemiology/*psychology Quality of Life/psychology Young Adult LA - eng N1 - 1526-4610 Smitherman, Todd A McDermott, Michael J Buchanan, Erin M Journal Article United States Headache. 2011 Apr;51(4):581-9. doi: 10.1111/j.1526-4610.2011.01857.x. PY - 2011 SN - 0017-8748 SP - 581-9 ST - Negative impact of episodic migraine on a university population: quality of life, functional impairment, and comorbid psychiatric symptoms T2 - Headache TI - Negative impact of episodic migraine on a university population: quality of life, functional impairment, and comorbid psychiatric symptoms VL - 51 ID - 3600 ER - TY - JOUR AB - Purpose of review The regulation of strong emotions has important implications for health, particularly among individuals with chronic illness. We focus this brief review on effective psychosocial interventions that emphasize and teach skills to improve emotion regulation in the context of health-related outcomes. Recent findings Recent work in the area of emotion-regulation interventions has tested the effects of emotion-regulation family therapy, group-based emotion-regulation psychotherapy, expressive writing, and school-based prevention programs. Emotion-regulation psychotherapy for families shows some benefits for both patients and their family members. Group emotion-regulation interventions and expressive writing result in physical and psychosocial improvement for patients with medical or psychiatric illness. School-based programs show improved emotion knowledge, emotion regulation, and emotional competence, relative to standard academic curricula and existing prevention programs. Summary Evidence generally supports the use of a variety of emotion-regulation interventions to improve health and well being in at-risk and clinical populations, although factors related to treatment response warrant additional research. AN - WOS:000264365900013 AU - Smyth, J. M. AU - Arigo, D. DA - Mar DO - 10.1097/YCO.0b013e3283252d6d IS - 2 N1 - Smyth, Joshua M. Arigo, Danielle Smyth, Joshua/0000-0002-0904-5390 PY - 2009 SN - 0951-7367 SP - 205-210 ST - Recent evidence supports emotion-regulation interventions for improving health in at-risk and clinical populations T2 - Current Opinion in Psychiatry TI - Recent evidence supports emotion-regulation interventions for improving health in at-risk and clinical populations UR - ://WOS:000264365900013 VL - 22 ID - 2608 ER - TY - JOUR AB - As an increase in pain symptoms among children has been shown in the last decades, the aim of this study was to describe perceptions of recurrent pain, measured physical fitness and levels of reported physical activity (PA) in children, and to investigate if any associations between PA, fitness and recurrent pain could be identified. A school-based study comprised 206 Swedish children 8-12 years old, 114 boys, 92 girls. A questionnaire with questions about perceived pain, self-reported PA and lifestyle factors was used. Health-related fitness was assessed by 11 physical tests. A physical index was calculated from these tests as a z score. High physical index indicated high fitness and low physical index indicated low fitness. ANOVA test, chi-square test and logistic regression analysis were used to compare active and inactive children. The prevalence of one pain location (head, abdomen or back) was 26%, two 11% and three 4% (n=206). Female gender, living in single-parent families, low PA and low subjective health were associated with reported recurrent pain. Children reporting high levels of PA had high physical index and reported low prevalence of pain symptoms. The physical index and level of self-reported PA decreased gradually the more pain locations. Physically active children had higher fitness levels and reported less pain symptoms than inactive peers. Coping with pain is an integral part of PA, and active children learn to cope with unpleasant body sensations which together with high fitness may reduce the perception of pain. AD - a School of Education and Environment , Kristianstad University , Kristianstad , Sweden. AN - 24050478 AU - Sollerhed, A. C. AU - Andersson, I. AU - Ejlertsson, G. DO - 10.1080/17461391.2013.767946 DP - NLM ET - 2013/09/21 IS - 5 KW - Body Mass Index Child Exercise Test/*adverse effects Female Humans Male Motor Activity/*physiology Pain/diagnosis/*etiology Pain Measurement Physical Education and Training Physical Fitness/*physiology Recurrence *Schools Self Report Surveys and Questionnaires LA - eng N1 - 1536-7290 Sollerhed, Ann-Christin Andersson, Ingemar Ejlertsson, Göran Journal Article England Eur J Sport Sci. 2013;13(5):591-8. doi: 10.1080/17461391.2013.767946. Epub 2013 Feb 8. PY - 2013 SN - 1536-7290 SP - 591-8 ST - Recurrent pain and discomfort in relation to fitness and physical activity among young school children T2 - Eur J Sport Sci TI - Recurrent pain and discomfort in relation to fitness and physical activity among young school children VL - 13 ID - 3176 ER - TY - JOUR AB - Migraine is an expensive disorder in terms of lost productivity and its deleterious impact on health-related quality of life (QOL). In addition to lost wages and productivity due to absenteeism, many patients with migraine also experience reduced productivity while at work and disruption of their family, social, and leisure activities. Even a migraine of moderate intensity can impair function and productivity, which emphasizes the importance of therapy that achieves complete, as opposed to partial, pain relief. Rapid onset of complete relief with abatement of migraine-associated symptoms has been reported to be most relevant for patient QOL and satisfaction with migraine therapy. Several instruments have been developed for measuring health-related QOL. Both general and migraine-specific instruments have been useful in assessing the impact of migraine and migraine therapy on health-related QOL; migraine-specific instruments may be more sensitive in measuring the effects of pharmacologic intervention. Compared with placebo, rizatriptan improved productivity in migraine patients. Compared with usual care, rizatriptan had favorable effects on all five domains of the 24-Hour Migraine Quality of Life questionnaire. AN - WOS:000165313100007 AU - Solomon, G. D. AU - Santanello, N. DA - Nov IS - 9 N1 - Solomon, GD Santanello, N 1526-632x 2 PY - 2000 SN - 0028-3878 SP - S29-S35 ST - Impact of migraine and migraine therapy on productivity and quality of life T2 - Neurology TI - Impact of migraine and migraine therapy on productivity and quality of life UR - ://WOS:000165313100007 VL - 55 ID - 2862 ER - TY - JOUR AB - PURPOSE: This study aims to characterize the symptom burden and life challenges that chordoma patients and their caregivers experience. METHODS: In this cross-sectional study, we analyzed data from the Chordoma Foundation online community survey conducted in 2014. Frequency counts and percentages were calculated to determine the prevalence of self-reported symptoms and life challenges in the sample. We used Fisher's exact test to compare self-reported symptoms among subgroups with different disease status, tumor locations, and treatments received. RESULTS: Among the survey participants, 358 identified themselves as chordoma patients and 208 as caregivers. The majority of the patients were over 45 years (72%), male (56%), educated beyond high school degree (87%), and from North America (77%). Skull base was the most prevalent tumor location (40%). Chronic pain (38%) was the most commonly reported symptom followed by depression or severe anxiety (35%), and chronic fatigue (34%). Among patients, the most commonly-reported challenges included delayed diagnosis (37%), long-term disability (33%), and change in career or reduced ability to work (33%). For caregivers, grief (55%), delayed diagnosis (47%), and difficulty helping the patient cope with his or her disease (45%) were most common. CONCLUSIONS: Our study findings suggest a high symptom burden and life challenges among chordoma patients and their caregivers. This study provides preliminary, limited estimates of the prevalence of a wide range of self-reported symptoms and challenges that will inform the assessment of patient-reported outcomes in future clinical trials and help clinicians better manage chordoma patients' symptoms. AD - Department of Health Policy and Management, The University of North Carolina at Chapel Hill, 1105A McGavran-Greenberg Hall, CB #7411, Chapel Hill, NC, 27599-7411, USA. psong@unc.edu. Department of Health Policy and Management, The University of North Carolina at Chapel Hill, 1105A McGavran-Greenberg Hall, CB #7411, Chapel Hill, NC, 27599-7411, USA. Chordoma Foundation, Durham, NC, USA. AN - 28315176 AU - Song, P. H. AU - Beyhaghi, H. AU - Sommer, J. AU - Bennett, A. V. C2 - PMC5509836 DA - Aug DO - 10.1007/s11136-017-1544-2 DP - NLM ET - 2017/03/21 IS - 8 KW - Adolescent Adult Aged Aged, 80 and over Caregivers Chordoma/*psychology Cross-Sectional Studies Female Humans Male Middle Aged Quality of Life/*psychology Young Adult *Chordoma *Patient-reported outcomes *Quality of life *Symptom burden Josh Sommer is the executive director of the Chordoma Foundation. Hadi Beyhaghi has no conflict of interest relevant to this manuscript. Antonia V. Bennett has no conflict of interest relevant to this manuscript. ETHICAL APPROVAL: This article does not contain any studies with human participants performed by any of the authors. The authors analyzed data from the Chordoma Foundation community survey. The authors also sought IRB approval early on, and the study was determined to be exempt. LA - eng N1 - 1573-2649 Song, Paula H Beyhaghi, Hadi Sommer, Josh Bennett, Antonia V Journal Article Qual Life Res. 2017 Aug;26(8):2237-2244. doi: 10.1007/s11136-017-1544-2. Epub 2017 Mar 17. PY - 2017 SN - 0962-9343 (Print) 0962-9343 SP - 2237-2244 ST - Symptom burden and life challenges reported by adult chordoma patients and their caregivers T2 - Qual Life Res TI - Symptom burden and life challenges reported by adult chordoma patients and their caregivers VL - 26 ID - 4070 ER - TY - JOUR AB - Background and aims: Persistent (chronic) pain is a common phenomenon in adolescents. When young people are referred to a pain clinic, they usually have amplified pain signals, with pain syndromes of unconfirmed ethology, such as fibromyalgia and complex regional pain syndrome (CRPS). Pain is complex and seems to be related to a combination of illness, injury, psychological distress, and environmental factors. These young people are found to have higher levels of distress, anxiety, sleep disturbance, and lower mood than their peers and may be in danger of entering adulthood with mental and physical problems. In order to understand the complexity of persistent pain in adolescents, there seems to be a need for further qualitative research into their lived experiences. The aim of this study was to explore adolescents' experiences of complex persistent pain and its impact on everyday life. Methods: The study has an exploratory design with individual in-depth interviews with six youths aged 12-19, recruited from a pain clinic at a main referral hospital in Norway. A narrative approach allowed the informants to give voice to their experiences concerning complex persistent pain. A hermeneutic analysis was used, where the research question was the basis for a reflective interpretation. Results: Three main themes were identified: (1) a life with pain and unpleasant bodily expressions; (2) an altered emotional wellbeing; and (3) the struggle to keep up with everyday life. The pain was experienced as extremely strong, emerging from a minor injury or without any obvious causation, and not always being recognised by healthcare providers. The pain intensity increased as the suffering got worse, and the sensation was hard to describe with words. Parts of their body could change in appearance, and some described having pain-attacks or fainting. The feeling of anxiety was strongly connected to the pain. Despair and uncertainty contributed to physical disability, major sleep problems, school absence, and withdrawal from leisure activities. Their parents were supportive, but sometimes more emotionally affected than themselves. The adolescents described how they strived for normality and to not become an outsider. Being met with necessary facilitation from school was important, as well as keeping up with friends. These adolescents had all been treated by an interdisciplinary pain team, and stated that they had an optimistic view of the future, despite still having some symptoms. Conclusions: The study provides new insights into adolescents' own experiences of complex persistent pain occurring unexpectedly, developing dramatically over time, and influencing all parts of their everyday lives. The adolescents entered vicious cycles, with despair and decreased physical and social functioning, with the risk of isolation and role-loss. However, these young people seem to have a strong motivation to strive for normalcy. (C) 2017 Scandinavian Association for the Study of Pain. Published by Elsevier B.V. All rights reserved. AN - WOS:000405971800024 AU - Sorensen, K. AU - Christiansen, B. DA - Apr DO - 10.1016/j.sjpain.2017.02.002 N1 - Sorensen, Kari Christiansen, Bjorg 1877-8879 PY - 2017 SN - 1877-8860 SP - 106-112 ST - Adolescents' experience of complex persistent pain T2 - Scandinavian Journal of Pain TI - Adolescents' experience of complex persistent pain UR - ://WOS:000405971800024 VL - 15 ID - 2104 ER - TY - JOUR AB - OBJECTIVE: The purpose of this study is to provide an expanded description of Danish chiropractic patients and to compare characteristics seen in a survey from 1999 with those seen in 2002. METHODS: All chiropractic clinics in Denmark were asked to collect information on new patients during 1 randomly assigned week in 2002 using a survey questionnaire. All 52 weeks of the year 2002 were represented with an even dispersion of weeks (182 clinics participated). Outcome measures included age, sex, education, occupation, location and duration of chief complaint, pain intensity, limitation of activities of daily living, mode of referral, duration of sick leave, previous treatments, comorbidity, SF-12, smoking habits, and use of x-ray. RESULTS: Eighty-five percent of all chiropractic clinics in Denmark participated in the study, and 1595 patients (81%) filled out a self-administered questionnaire. As in 1999, the most frequent area of complaint was pain related to the lower back and pelvis (49%). Contrary to the 1999 survey, most of the patients (64%) had complaints of less than 4 weeks of duration. Twenty-nine percent of the patients had been off work because of their symptoms; most of these for less than 1 week. Fifty-one percent of all patients were referred to chiropractors in 2002 (doubling since 1999). Referrals from general medical practitioners rose from 11% in 1999 to 17% in 2002. Sixty percent of all patients had similar symptoms in the past, and approximately half had previously received treatment of the same or a similar problem. Thirty percent of first-time chiropractic patients were x-rayed. Compared with general population measures, Danish chiropractic patients had significantly worse physical health status measured by the SF-12. CONCLUSIONS: Most Danish chiropractic patients complain of pain related to the spine, especially the lower back, with duration of symptoms of less than 4 weeks, and many with recurrent back pain. Referrals from general medical practitioners have increased since 1999. AD - Private Practice of Chiropractic, Aarhus, Denmark. linepress@hotmail.com AN - 16904487 AU - Sorensen, L. P. AU - Stochkendahl, M. J. AU - Hartvigsen, J. AU - Nilsson, N. G. DA - Jul-Aug DO - 10.1016/j.jmpt.2006.06.001 DP - NLM ET - 2006/08/15 IS - 6 KW - Absenteeism Activities of Daily Living Adolescent Adult Aged Aged, 80 and over Back Pain/complications/diagnostic imaging/physiopathology/*therapy Child Child, Preschool Comorbidity Denmark Female Health Status Indicators Humans Infant Infant, Newborn Male Manipulation, Chiropractic Middle Aged *Patients Pelvic Pain/complications/diagnostic imaging/physiopathology/*therapy Radiography Recurrence Referral and Consultation/statistics & numerical data Smoking Surveys and Questionnaires Time Factors LA - eng N1 - 1532-6586 Sorensen, Line Press Stochkendahl, Mette Jensen Hartvigsen, Jan Nilsson, Niels Grunnet Comparative Study Journal Article Research Support, Non-U.S. Gov't United States J Manipulative Physiol Ther. 2006 Jul-Aug;29(6):419-24. doi: 10.1016/j.jmpt.2006.06.001. PY - 2006 SN - 0161-4754 SP - 419-24 ST - Chiropractic patients in Denmark 2002: an expanded description and comparison with 1999 survey T2 - J Manipulative Physiol Ther TI - Chiropractic patients in Denmark 2002: an expanded description and comparison with 1999 survey VL - 29 ID - 3453 ER - TY - JOUR AB - OBJECTIVE: Low back pain (LBP) is a common cause of disability among people of working age. We investigated the incidence of consultation for work related LBP and of work absence, and determined the prevalence of continued work disability due to LBP in Argentina. METHODS: Our study population comprised 139,740 fulltime workers (mean age 34.4 yrs, range 17-79). An episode of work related LBP was defined as patient consulting because of acute LBP while at work or while traveling to/from work. RESULTS: In a 6 month period 360 episodes of acute LBP were reported in 69,329 worker-years of exposure to risk; thus the episode incidence rate was 5.2/1000 worker-years. This was the third most frequent work related injury. Twenty-one patients (5.8% of episodes) were lost to followup. Those with LBP were significantly older than the population at risk (p < 0.001) and were predominantly men (p < 0.001). In 244 episodes (72%) pain onset was related to heavy physical work and in 46 (13.6%) it followed trauma to the back. Surgery was performed in 9 (2.7%) cases. In total, 322 (98%) patients were absent beyond the day of the injury (median number of days of work absence, 7 days; range 0-422 days). Surgical patients lost significantly more days of work (p < 0.01). Seven patients (2%) remained off work more than 180 days: 2 were declared disabled, 3 moved to lighter jobs, and only 2 (28.5%) returned to their previous job. CONCLUSION: The incidence of consultation for work related LBP was 5.2/1000 worker-years. This was the third most frequent work related injury. Most patients had some work absenteeism. Surgery did not shorten recovery times. Only a minority of patients off work for 6 months or more were able to return to their previous job. AD - Rheumatology Section, Medical Services, Hospital Italiano de Buenos Aires, Capital Federal, Argentina. AN - 12022319 AU - Soriano, E. R. AU - Zingoni, C. AU - Lucco, F. AU - Catoggio, L. J. DA - May DP - NLM ET - 2002/05/23 IS - 5 KW - Absenteeism Adolescent Adult Aged Argentina/epidemiology Disability Evaluation Follow-Up Studies Humans Incidence Low Back Pain/*epidemiology Middle Aged Occupational Diseases/*epidemiology Prevalence Recurrence Referral and Consultation/*statistics & numerical data Sick Leave/statistics & numerical data LA - eng N1 - Soriano, Enrique R Zingoni, Carolina Lucco, Florencio Catoggio, Luis J Journal Article Research Support, Non-U.S. Gov't Canada J Rheumatol. 2002 May;29(5):1029-33. PY - 2002 SN - 0315-162X (Print) 0315-162x SP - 1029-33 ST - Consultations for work related low back pain in Argentina T2 - J Rheumatol TI - Consultations for work related low back pain in Argentina VL - 29 ID - 3325 ER - TY - JOUR AB - Context: To our knowledge, no population study examining psychosocial and psychiatric risk factors associated with cyberbullying among adolescents exists. Objective: To study cross-sectional associations between cyberbullying and psychiatric and psychosomatic problems among adolescents. Design: Population-based cross-sectional study. Setting: Finland. Participants: The sample consists of 2215 Finnish adolescents aged 13 to 16 years with complete information about cyberbullying and cybervictimization. Main Outcome Measures: Self-reports of cyberbullying and cybervictimization during the past 6 months. Results: In the total sample, 4.8% were cybervictims only, 7.4% were cyberbullies only, and 5.4% were cyberbully-victims. Cybervictim-only status was associated with living in a family with other than 2 biological parents, perceived difficulties, emotional and peer problems, headache, recurrent abdominal pain, sleeping difficulties, and not feeling safe at school. Cyberbully-only status was associated with perceived difficulties, hyperactivity, conduct problems, low prosocial behavior, frequent smoking and drunkenness, headache, and not feeling safe at school. Cyberbully-victim status was associated with all of these risk factors. Among cybervictims, being cyberbullied by a same-sex or opposite-sex adult, by an unknown person, and by a group of people were associated with fear for safety, indicating possible trauma. Conclusions: Both cyberbullying and cybervictimization are associated with psychiatric and psychosomatic problems. The most troubled are those who are both cyberbullies and cybervictims. This indicates the need for new strategies for cyberbullying prevention and intervention. AN - WOS:000279517800008 AU - Sourander, A. AU - Klomek, A. B. AU - Ikonen, M. AU - Lindroos, J. AU - Luntamo, T. AU - Koskelainen, M. AU - Ristkari, T. AU - Helenius, H. DA - Jul DO - 10.1001/archgenpsychiatry.2010.79 IS - 7 N1 - Sourander, Andre Klomek, Anat Brunstein Ikonen, Maria Lindroos, Jarna Luntamo, Terhi Koskelainen, Merja Ristkari, Terja Helenius, Hans Sourander, Andre/0000-0003-0361-7244 1538-3636 PY - 2010 SN - 0003-990X SP - 720-728 ST - Psychosocial Risk Factors Associated With Cyberbullying Among Adolescents A Population-Based Study T2 - Archives of General Psychiatry TI - Psychosocial Risk Factors Associated With Cyberbullying Among Adolescents A Population-Based Study UR - ://WOS:000279517800008 VL - 67 ID - 2545 ER - TY - JOUR AB - Back Pain is a common problem for adolescents and adults. it has high social but also economic importance in medicine and public health. Material and methods: A total of 2368 adolescents (1137 male, 1231 female; age 14.5 +/- 0.65, 13-18 years) who had undergone obligatory public health examination were included into the study. In the beginning the adolescents had to answer a questionnaire. Here were asked frequency and localisation of muscolu-skeletal and back pain but also social status and consumption of tobacco and alcoholic beverages. The clinical examination was performed by 4 well experienced school-doctors. At the beginning the doctors were instructed by an orthopaedic surgeon and the criteria for clinical signs of back pathologies were standardized. Results: The overall prevalence of LBP was 45.5%. From these 38.2% adolescents had occasional back pain, 4% during physical activity, and 3.3% reported permanent pain. The prevalence of back pathologies was 28.1%. The prevalence of back pain without concomitant back pathologies was 29%. In 11.7% of the adolescents pathologies of the back were detected without any symptoms. The combination of back pain and back pathology was observed in 16.5%. Metaanalysis revealed the following significant risk factors (p < 0.05) for developing LBP: Female gender (OR = 1.6), visit of a middle school (OR=1.5) or visit of a high school (OR = 1.7), smoking (OR = 1.5), scoliosis (OR = 1.8), round back (OR=1.6), and inclined pelvic tilting pelvis (OR=1.4). Conclusions: In our adolescent population back pain is a common problem with an overall life time prevalence of 45,5%. Objective pathological changes as detected by clinical examination are only found in 28.1% of these children. Other factors such as female gender, alcohol or smoking seem to be related to a higher prevalence of LBP as well. Therefore, early preventive programs for this age group may reduce the prevalence of LBP. AN - WOS:000246691400002 AU - Spahn, G. AU - Hell, A. AU - Klinger, H. M. AU - Langlotz, A. AU - Muckley, T. AU - Schiele, R. DA - Apr DO - 10.1055/s-2007-961798 IS - 2 N1 - Spahn, G. Hell, A. Klinger, H. M. Langlotz, A. Mueckley, T. Schiele, R. PY - 2007 SN - 0940-6689 SP - 81-87 ST - Prevalence and associated factors of lower back pain in 2368 adolescents T2 - Physikalische Medizin Rehabilitationsmedizin Kurortmedizin TI - Prevalence and associated factors of lower back pain in 2368 adolescents UR - ://WOS:000246691400002 VL - 17 ID - 2697 ER - TY - JOUR AB - This study was designed to determine the effects of two teaching methods on children's ability to demonstrate and recall their mastery of proper lifting techniques. Seventy-six third and fifth grade public school children were divided by grade into three groups. Two of the groups (experimental) were taught the correct method for lifting a heavy object, either by lecture demonstration or guided discovery teaching format; one group (control) was not taught. The students' knowledge was measured pretest, one-week posttest, and eight-week posttest with a written and practical test. The students in the experimental groups in both grades significantly (p less than or equal to .001) increased their scores on the written portion of the test over those of the control groups on the one-week posttest. No group, however, showed significant gains on the practical portion. No differences were found between teaching methods. Results of this study stress the importance of evaluating verbally learned motor skills in a practical application format in school settings and in clinical patient education. AN - 6739547 AU - Spence, S. M. AU - Jensen, G. M. AU - Shepard, K. F. DA - Jul DO - 10.1093/ptj/64.7.1055 DP - NLM ET - 1984/07/01 IS - 7 KW - Child Educational Measurement Health Education/*methods Humans Intervertebral Disc Displacement/prevention & control *Movement *Posture Sciatica/prevention & control LA - eng N1 - Spence, S M Jensen, G M Shepard, K F Comparative Study Journal Article United States Phys Ther. 1984 Jul;64(7):1055-61. doi: 10.1093/ptj/64.7.1055. PY - 1984 SN - 0031-9023 (Print) 0031-9023 SP - 1055-61 ST - Comparison of methods of teaching children proper lifting techniques T2 - Phys Ther TI - Comparison of methods of teaching children proper lifting techniques VL - 64 ID - 3718 ER - TY - JOUR AB - Schoolbag weight in schoolchildren is a recurrent and contentious issue within the educational and health sphere. Excessive schoolbag weight can lead to back pain in children, which increases the risk of chronic back pain in adulthood. There is limited research regarding this among the Maltese paediatric population. A cross-sectional study was undertaken across all schools in Malta among students aged 8-13 years (inclusive). Data were collected using a questionnaire detailing schoolbag characteristics, self-reported pain and demographic variables, such as age and gender. Structured interviews with participants were also carried out by physiotherapists. A total of 4005 participants were included in the study, with 20% of the total Malta schoolchildren population. Over 70% of the subjects had a schoolbag that exceeded the recommended 10% bag weight to body ratio. A total of 32% of the sample complained of back pain, with 74% of these defining it as low in intensity on the face pain scale-revised. The presence of back pain was statistically related to gender, body mass index (BMI), school and bag weight to body weight ratio. After adjusting for other factors, self-reported back pain in schoolchildren is independently linked to carrying heavy schoolbags. This link should be addressed to decrease the occurrence of back pain in this age group. AU - Spiteri, Karl AU - Busuttil, Maria-Louisa AU - Aquilina, Samuel AU - Gauci, Dorothy AU - Camilleri, Erin AU - Grech, Victor DA - 2017/05// DO - 10.1177/2049463717695144 DP - PubMed IS - 2 J2 - Br J Pain KW - Back pain national obesity schoolbags schoolchildren LA - eng PY - 2017 SN - 2049-4637 SP - 81-86 ST - Schoolbags and back pain in children between 8 and 13 years T2 - British Journal of Pain TI - Schoolbags and back pain in children between 8 and 13 years: a national study UR - http://www.ncbi.nlm.nih.gov/pubmed/28491300 VL - 11 ID - 71 ER - TY - JOUR AB - The most common causes of serious low back pain in children include spondylolysis, Scheuermann disease and musculoligamentous injury. Questions should be asked about the mechanism of onset and exacerbating factors, and the frequency, duration and severity of the pain. The examination should check gait and alignment, flexibility, strength and reflexes, and localize and evaluate the pain. Warning signs of serious problems include constant pain in a child younger than 11 years of age that lasts for several weeks or occurs spontaneously at night, repeatedly interferes with school, play or sports, or is associated with marked stiffness and limitation of motion, fever or neurologic abnormalities. Pain at the lumbosacral junction may suggest spondylolysis or spondylolisthesis. Scheuermann disease is diagnosed by the observance of wedging, irregularity or growth disturbance of three successive vertebrae. Musculoligamentous pain may result from injury to or overuse of muscles or joints of the back. Rare causes include discitis, tuberculosis, bone or spinal cord tumor, pyelonephritis and retroperitoneal infection. AN - WOS:A1996VR60700018 AU - Sponseller, P. D. DA - Nov IS - 6 N1 - Sponseller, PD PY - 1996 SN - 0002-838X SP - 1933-1941 ST - Evaluating the child with back pain T2 - American Family Physician TI - Evaluating the child with back pain UR - ://WOS:A1996VR60700018 VL - 54 ID - 2917 ER - TY - JOUR AB - For children with Cystic Fibrosis (CF) suffering from acute recurrent pancreatitis (ARP), abdominal pain can be severe, difficult to treat, impair their quality of life, affect participation at school, and can lead to chronic opioid dependence. Total pancreatectomy with islet autotransplantation (TPIAT) is an uncommon treatment that is reserved for refractory cases of ARP. We present a case of a 4 year old female with pancreatic-sufficient CF. refractory ARP, frequent hospital admissions for abdominal pain, and continued growth failure despite gastrostomy tube and parenteral nutrition. One year after successful TPIAT, the patient is insulin-independent, growing well, and has not been re-hospitalized for abdominal pain. To our knowledge, this is the youngest patient with CF to undergo TPIAT for debilitating ARP. With CFTR modulators restoring some pancreatic function, CF clinicians should have increased vigilance for the development of ARP. (C) 2019 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved. AN - WOS:000542303600005 AU - St Onge, I. AU - Nathan, J. D. AU - Abu-El-Haija, M. AU - Chini, B. A. DA - Sep DO - 10.1016/j.jcf.2019.07.009 IS - 5 N1 - St Onge, Ina Nathan, Jaimie D. Abu-El-Haija, Maisam Chini, Barbara A. 1873-5010 PY - 2019 SN - 1569-1993 SP - E53-E55 ST - Total pancreatectomy with islet autotransplantation in a pancreatic-sufficient cystic fibrosis patient T2 - Journal of Cystic Fibrosis TI - Total pancreatectomy with islet autotransplantation in a pancreatic-sufficient cystic fibrosis patient UR - ://WOS:000542303600005 VL - 18 ID - 1885 ER - TY - BOOK A2 - Dobe, M. A2 - Zernikow, B. AB - Chronic pain is common and affects approximately one-quarter to one-third of all children and adolescents. Older age, female sex and stress could be identified as risk factors. Overall, 5% of all children and adolescents suffer severely from chronic pain and are in need of an interdisciplinary pain treatment. AN - WOS:000550989700005 AU - Stahlschmidt, L. DO - 10.1007/978-3-030-19201-3_1 N1 - Stahlschmidt, Lorin PY - 2019 SN - 978-3-030-19201-3; 978-3-030-19200-6 SP - 3-6 ST - Epidemiology of Chronic Pain in Children and Adolescents T2 - Practical Treatment Options for Chronic Pain in Children and Adolescents: An Interdisciplinary Therapy Manual, 2nd Edition TI - Epidemiology of Chronic Pain in Children and Adolescents UR - ://WOS:000550989700005 ID - 1960 ER - TY - JOUR AB - Combining written and video material could increase the impact of health education for people with less education, but more evidence is needed about the impact of combined materials in different formats, especially in the context of chronic pain self-management. This study tested the impact of combining written information about self-managing chronic joint pain, which used language at a high reading level, with a DVD containing narrative video material presented directly by patients, using language at a lower reading level. Physical and mental health-related quality of life (36-Item Short Form Health Survey) was measured among 107 men with hemophilia before and 6 months after being randomly assigned to receive an information booklet alone or the booklet plus the DVD. Analysis of covariance was used to compare health outcomes between randomized groups at follow-up, using the baseline measures as covariates, with stratified analyses for groups with different levels of education. The DVD significantly improved mental health-related quality of life among those with only high school education. Video material could therefore supplement written information to increase its impact on groups with less education, and combined interventions of this type could help to achieve health benefits for disadvantaged groups who are most in need of intervention. AD - Centre for Psychological Research, Department of Life Sciences, University of Derby, Derby, UK. AN - 26316809 AU - Stalker, C. AU - Elander, J. C2 - PMC4548759 DO - 10.2147/jpr.S85741 DP - NLM ET - 2015/09/01 KW - Dvd hemophilia video intervention LA - eng N1 - 1178-7090 Stalker, Carol Elander, James Journal Article J Pain Res. 2015 Aug 20;8:581-90. doi: 10.2147/JPR.S85741. eCollection 2015. PY - 2015 SN - 1178-7090 (Print) 1178-7090 SP - 581-90 ST - Effects of a pain self-management intervention combining written and video elements on health-related quality of life among people with different levels of education T2 - J Pain Res TI - Effects of a pain self-management intervention combining written and video elements on health-related quality of life among people with different levels of education VL - 8 ID - 4209 ER - TY - JOUR AB - Recurrent pains are a complex set of conditions that cause great discomfort and impairment in children and adults. The objectives of this study were to (a) describe the frequency of headache, stomachache, and backache in a representative Canadian adolescent sample and (b) determine whether a set of psychosocial factors, including background factors (i.e., sex, pubertal status, parent chronic pain), external events (i.e., injury, illness/hospitalization, stressful-life events), and emotional factors(i.e., anxiety/depression, self-esteem) were predictive of these types of recurrent pain. Statistics Canada's National Longitudinal Survey of Children and Youth was used to assess a cohort of 2488 10- to 11-year-old adolescents up to five times, every 2 years. Results showed that, across 12-19 years of age, weekly or more frequent rates ranged from 26.1%-31.8% for headache, 13.5-22.2% for stomachache, and 17.6-25.8% for backache. Chi-square tests indicated that girls had higher rates of pain than boys for all types of pain, at all time points. Structural equation modeling using latent growth curves showed that sex and anxiety/depression at age 10-11 years was predictive of the start- and end-point intercepts (i.e., trajectories that indicated high levels of pain across time) and/or slopes (i.e., trajectories of pain that increased over time) for all three types of pain. Although there were also other factors that predicted only certain pain types or certain trajectory types, overall the results of this study suggest that adolescent recurrent pain is very common and that psychosocial factors can predict trajectories of recurrent pain over time across adolescence. (c) 2007 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved. AN - WOS:000258746100005 AU - Stanford, E. A. AU - Chambers, C. T. AU - Biesanz, J. C. AU - Chen, E. DA - Aug DO - 10.1016/j.pain.2007.10.032 IS - 1 N1 - Stanford, Elizabeth A. Chambers, Christine T. Biesanz, Jeremy C. Chen, Edith Chambers, Christine T./ABA-9257-2020 Chambers, Christine T./0000-0002-7138-916X PY - 2008 SN - 0304-3959 SP - 11-21 ST - The frequency, trajectories and predictors of adolescent recurrent pain: A population-based approach T2 - Pain TI - The frequency, trajectories and predictors of adolescent recurrent pain: A population-based approach UR - ://WOS:000258746100005 VL - 138 ID - 2639 ER - TY - JOUR AB - OBJECTIVE: To estimate the prevalence of comorbidity among people with arthritis in the US adult population and to determine the role of comorbidity in accounting for the association of arthritis with days out of role (a measure of inability to work or carry out normal activities). METHODS: Data come from the National Comorbidity Survey Replication (NCS-R), a nationally representative household survey of 9,282 respondents ages 18 and older carried out in 2001 to 2003. Arthritis was assessed by self-report in a chronic-conditions checklist, along with a wide range of other physical conditions. Mental and substance use disorders were ascertained with the World Health Organization Composite International Diagnostic Interview (CIDI). Number of days out of role was assessed for the 30 days before the interview. RESULTS: Arthritis was reported by 27.3% of respondents, 80.9% of whom also reported at least one other physical or mental disorder, including 45.6% with another chronic pain condition, 62.3% with another chronic physical condition, and 24.3% with a 12-month mental disorder. Arthritis was significantly associated with days out of role, but comorbidity explained more than half of this association. No significant interactions were found between arthritis and the other conditions in predicting days out of role. CONCLUSION: Comorbidity is the rule rather than the exception among people with arthritis. Comorbidity accounts for most of the days out of role associated with arthritis. The societal burden of arthritis needs to be understood and managed within the context of these comorbid conditions. AD - Department of Health, West Chester University and Galt Associates West Chester, PA, USA. pstang@galt-assoc.com AN - 16449426 AU - Stang, P. E. AU - Brandenburg, N. A. AU - Lane, M. C. AU - Merikangas, K. R. AU - Von Korff, M. R. AU - Kessler, R. C. C2 - PMC1941781 C6 - NIHMS22866 DA - Jan-Feb DO - 10.1097/01.psy.0000195821.25811.b4 DP - NLM ET - 2006/02/02 IS - 1 KW - Absenteeism Activities of Daily Living Adolescent Adult Arthritis/*epidemiology/psychology Chronic Disease/epidemiology Comorbidity Employment Female Humans Male Mental Disorders/*epidemiology Middle Aged Prevalence United States/epidemiology LA - eng N1 - 1534-7796 Stang, Paul E Brandenburg, Nancy A Lane, Michael C Merikangas, Kathleen R Von Korff, Michael R Kessler, Ronald C R01 DA016558/DA/NIDA NIH HHS/United States R01-AG022232/AG/NIA NIH HHS/United States U01-MH60220/MH/NIMH NIH HHS/United States R01 MH069864/MH/NIMH NIH HHS/United States R01-MH069864/MH/NIMH NIH HHS/United States K05 DA015799/DA/NIDA NIH HHS/United States U01 MH060220/MH/NIMH NIH HHS/United States R13-MH066849/MH/NIMH NIH HHS/United States U13 MH066849/MH/NIMH NIH HHS/United States R01-TW006481/TW/FIC NIH HHS/United States R13 MH066849/MH/NIMH NIH HHS/United States K08 AG022232/AG/NIA NIH HHS/United States Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Psychosom Med. 2006 Jan-Feb;68(1):152-8. doi: 10.1097/01.psy.0000195821.25811.b4. PY - 2006 SN - 0033-3174 (Print) 0033-3174 SP - 152-8 ST - Mental and physical comorbid conditions and days in role among persons with arthritis T2 - Psychosom Med TI - Mental and physical comorbid conditions and days in role among persons with arthritis VL - 68 ID - 3721 ER - TY - JOUR AB - Data from the 1989 National Health Interview Survey concerning migraine occurrence and impairment were analyzed to assess the impact of migraine on the US population. About four of every one hundred persons in the United States were found to have migraine, accounting for nearly 10 million individuals. Migraine was most prevalent in those aged 25 to 44 years and was about 2.5 times more frequent in females than males. Migraine was most common in whites (85%) and those with low household income. In women, migraine prevalence increased with the level of education. About 10% of migrainous children missed at least one day of school over a two-week period due to migraine; nearly 1% missed four days. Migraineurs were bedridden for about three million days per month and had an estimated 74.2 million days per year of restricted activity due to migraine. The potential cost of lost productivity was estimated at $1.4 billion per year for the estimated 6,196,378 migraineurs who worked outside the home. It is difficult to derive similar estimates for costs of lost productivity in housewives; however, housewives experienced an estimated 38 million days per year of restricted activity. Eighty-five percent of females and 77% of males reported a physician visit at some point for their migraine. Migraine is a relatively common disease whose social and financial impact has been poorly understood. AD - Pharmacoeconomic Research, Glaxo Research Institute, Research Triangle Park, NC 27709. AN - 8436495 AU - Stang, P. E. AU - Osterhaus, J. T. DA - Jan DO - 10.1111/j.1526-4610.1993.hed3301029.x DP - NLM ET - 1993/01/01 IS - 1 KW - Activities of Daily Living Adolescent Adult Aged Child Child, Preschool Demography Female Health Services/statistics & numerical data *Health Surveys Humans Infant Male Middle Aged Migraine Disorders/*epidemiology/physiopathology Prevalence United States/epidemiology LA - eng N1 - Stang, P E Osterhaus, J T Journal Article United States Headache. 1993 Jan;33(1):29-35. doi: 10.1111/j.1526-4610.1993.hed3301029.x. PY - 1993 SN - 0017-8748 (Print) 0017-8748 SP - 29-35 ST - Impact of migraine in the United States: data from the National Health Interview Survey T2 - Headache TI - Impact of migraine in the United States: data from the National Health Interview Survey VL - 33 ID - 3471 ER - TY - JOUR AB - The purpose of this study was to compare the effect of the McKenzie method of treatment with patient education in "mini back school" in patients with acute low-back pain. The study included 100 patients, 23 women and 77 men with the average age 34.4 +/- 9.7 (range 18-61) years. The study included only those who were employed. The patients were randomly allocated to two groups, one group receiving treatment according to the McKenzie technique and the other group receiving education in a "mini back school." Assessments were made after 3 weeks by an independent observer and after 52 weeks they were seen by one of the authors. Patients were assessed on seven variables: return to work, sick-leave during the initial episode, sick-leave during recurrences, recurrences of pain during the year of observation, patients' ability to self-help, pain and movement. Although the effect of attention placebo cannot be ruled out, the results demonstrated that the McKenzie method of treatment for patients with acute low-back pain was superior for five out of seven variables studied. The only variables that did not show any statistically significant differences were sick-leave during recurring episodes of pain and patients' ability to self-help. AD - Department of Orthopaedics, Malmö General Hospital, Lund University, Sweden. AN - 2139241 AU - Stankovic, R. AU - Johnell, O. DA - Feb DP - NLM ET - 1990/02/01 IS - 2 KW - Absenteeism Acute Disease Adolescent Adult Back Pain/physiopathology/*therapy Female Humans Lumbosacral Region Male Middle Aged Movement *Patient Education as Topic *Physical Therapy Modalities Prospective Studies Randomized Controlled Trials as Topic Recurrence Spine/physiopathology LA - eng N1 - Stankovic, R Johnell, O Clinical Trial Comparative Study Journal Article Randomized Controlled Trial United States Spine (Phila Pa 1976). 1990 Feb;15(2):120-3. PY - 1990 SN - 0362-2436 (Print) 0362-2436 SP - 120-3 ST - Conservative treatment of acute low-back pain. A prospective randomized trial: McKenzie method of treatment versus patient education in "mini back school" T2 - Spine (Phila Pa 1976) TI - Conservative treatment of acute low-back pain. A prospective randomized trial: McKenzie method of treatment versus patient education in "mini back school" VL - 15 ID - 3441 ER - TY - JOUR AB - BACKGROUND: Pain and agitation are common experiences of patients in pediatric cardiac intensive care units. Variability in assessments by health care providers, communication, and treatment of pain and agitation creates challenges in management of pain and sedation. OBJECTIVES: To develop guidelines for assessment and treatment of pain, agitation, and delirium in the pediatric cardiac intensive unit in an academic children's hospital and to document the effects of implementation of the guidelines on the interprofessional team's perception of care delivery and team function. METHODS: Before and after implementation of the guidelines, interprofessional team members were surveyed about the members' perception of analgesia, sedation, and delirium management RESULTS: Members of the interprofessional team felt more comfortable with pain and sedation management after implementation of the guidelines. Team members reported improvements in team communication on patients' comfort. Members thought that important information was less likely to be lost during transfer of care. They also noted that the team carried out comfort management plans and used pharmacological and nonpharmacological therapies better after implementation of the guidelines than they did before implementation. CONCLUSIONS: Guidelines for pain and sedation management were associated with perceived improvements in team function and patient care by members of the interprofessional team. AD - Sandra L. Staveski is an assistant professor at Cincinnati Children's Hospital Medical Center, Department of Research in Patient Services, and the Heart Institute, Cincinnati, Ohio. sandra.staveski@cchmc.org. May Wu is a clinical pharmacist at Lucile Packard Children's Hospital Stanford, Palo Alto, California. sandra.staveski@cchmc.org. Tiffany M. Tesoro is a clinical pharmacist in the cardiovascular intensive care unit and coordinates the PGY-1 pharmacy residency program at Lucile Packard Children's Hospital-Stanford. She is also an assistant clinical professor, School of Pharmacy, University of California, San Francisco, California. sandra.staveski@cchmc.org. Stephen J. Roth is chief of the division of pediatric cardiology and professor of pediatrics (cardiology), Stanford University School of Medicine, Stanford, California, and the director of the children's heart center at Lucile Packard Children's Hospital Stanford. sandra.staveski@cchmc.org. Michael J. Cisco is a clinical assistant professor of pediatrics, Pediatric Critical Care Medicine, University of San Francisco School of Medicine, San Francisco, California, and an attending physician in the pediatric cardiac intensive care unit, University of California San Francisco-Benioff Children's Hospital, San Francisco, California. sandra.staveski@cchmc.org. Sandra L. Staveski is an assistant professor at Cincinnati Children's Hospital Medical Center, Department of Research in Patient Services, and the Heart Institute, Cincinnati, Ohio. May Wu is a clinical pharmacist at Lucile Packard Children's Hospital Stanford, Palo Alto, California. Tiffany M. Tesoro is a clinical pharmacist in the cardiovascular intensive care unit and coordinates the PGY-1 pharmacy residency program at Lucile Packard Children's Hospital-Stanford. She is also an assistant clinical professor, School of Pharmacy, University of California, San Francisco, California. Stephen J. Roth is chief of the division of pediatric cardiology and professor of pediatrics (cardiology), Stanford University School of Medicine, Stanford, California, and the director of the children's heart center at Lucile Packard Children's Hospital Stanford. Michael J. Cisco is a clinical assistant professor of pediatrics, Pediatric Critical Care Medicine, University of San Francisco School of Medicine, San Francisco, California, and an attending physician in the pediatric cardiac intensive care unit, University of California San Francisco-Benioff Children's Hospital, San Francisco, California. AN - 28572103 AU - Staveski, S. L. AU - Wu, M. AU - Tesoro, T. M. AU - Roth, S. J. AU - Cisco, M. J. DA - Jun DO - 10.4037/ccn2017538 DP - NLM ET - 2017/06/03 IS - 3 KW - Adolescent Cardiovascular Nursing/*standards Child Child, Preschool Critical Care/*standards Female Humans Hypnotics and Sedatives/*standards/therapeutic use Infant Infant, Newborn Intensive Care Units, Pediatric/*standards Interprofessional Relations Male Pain/*drug therapy Pain Management/*standards Pediatric Nursing/*standards Practice Guidelines as Topic LA - eng N1 - 1940-8250 Staveski, Sandra L Wu, May Tesoro, Tiffany M Roth, Stephen J Cisco, Michael J Journal Article United States Crit Care Nurse. 2017 Jun;37(3):66-76. doi: 10.4037/ccn2017538. PY - 2017 SN - 0279-5442 SP - 66-76 ST - Interprofessional Team's Perception of Care Delivery After Implementation of a Pediatric Pain and Sedation Protocol T2 - Crit Care Nurse TI - Interprofessional Team's Perception of Care Delivery After Implementation of a Pediatric Pain and Sedation Protocol VL - 37 ID - 3574 ER - TY - JOUR AB - BACKGROUND: Homeopathy use continues to grow in many European countries, and some studies have examined the characteristics of patients using homeopathy within the general population. The aim of this study was to identify predictors for homeopathy use among internal medicine patients. PATIENTS AND METHODS: A cross-sectional analysis was conducted among all patients being referred to the Department of Internal and Integrative Medicine at Essen, Germany, over a 3-year period. The analysis examined whether patients had used homeopathy for their primary medical complaint before, the perceived benefit, and the perceived harm of homeopathy use. Odds ratios with 95% confidence intervals were calculated using multiple logistic regression analysis. RESULTS: Of 2,045 respondents, 715 (35.0%) reported having used homeopathy for their primary medical complaint (diagnosis according to the International Statistical Classification of Diseases and Related Health Problems), with 359 (50.2%) reporting perceived benefits and 15 (2.1%) reporting harm. Homeopathy use was positively associated with female gender, high school level education, suffering from fibromyalgia or subthreshold depression, and being fast food abstinent, while patients with osteoarthritis, spinal or other pain, smokers, and patients with a high external-social health locus of control were less likely to use homeopathy. CONCLUSION: Personal characteristics and health status may impact on the use and the perceived helpfulness of homeopathy. AD - Office of Research, Endeavour College of Natural Health, Brisbane, Australia. AN - 27811465 AU - Steel, A. AU - Cramer, H. AU - Leung, B. AU - Lauche, R. AU - Adams, J. AU - Langhorst, J. AU - Dobos, G. DO - 10.1159/000450818 DP - NLM ET - 2016/11/05 IS - 5 KW - Adult Age Factors Aged Attitude to Health Chronic Disease/*psychology/*therapy Chronic Pain/*psychology/*therapy Delivery of Health Care, Integrated Evidence-Based Medicine Female Health Behavior Health Services Research Humans *Internal Medicine Internal-External Control Male Materia Medica/*therapeutic use Middle Aged Patient Satisfaction Sex Factors Surveys and Questionnaires LA - eng N1 - 1661-4127 Steel, Amie Cramer, Holger Leung, Brenda Lauche, Romy Adams, Jon Langhorst, Jost Dobos, Gustav Journal Article Switzerland Forsch Komplementmed. 2016;23(5):284-289. doi: 10.1159/000450818. Epub 2016 Oct 7. PY - 2016 SN - 1661-4119 SP - 284-289 ST - Characteristics of Homeopathy Users among Internal Medicine Patients in Germany T2 - Forsch Komplementmed TI - Characteristics of Homeopathy Users among Internal Medicine Patients in Germany VL - 23 ID - 3257 ER - TY - JOUR AB - CONTEXT: Studies suggest that yoga is effective for moderate to severe chronic low back pain (cLBP) in diverse predominantly lower socioeconomic status populations. However, little is known about factors associated with benefit from the yoga intervention. OBJECTIVE: Identify factors at baseline independently associated with greater efficacy among participants in a study of yoga for cLBP. DESIGN: From September-December 2011, a 12-week randomized dosing trial was conducted comparing weekly vs. twice-weekly 75-minute hatha yoga classes for 95 predominantly low-income minority adults with nonspecific cLBP. Participant characteristics collected at baseline were used to determine factors beyond treatment assignment (reported in the initial study) that predicted outcome. We used bivariate testing to identify baseline characteristics associated with improvement in function and pain, and included select factors in a multivariate linear regression. SETTING: Recruitment and classes occurred in an academic safety-net hospital and five affiliated community health centers in Boston, Massachusetts. PARTICIPANTS: Ninety-five adults with nonspecific cLBP, ages ranging from 20-64 (mean 48) years; 72 women and 23 men. OUTCOME MEASURES: Primary outcomes were changes in back-related function (modified Roland-Morris Disability Questionnaire, RMDQ; 0-23) and mean low back pain intensity (0-10) in the previous week, from baseline to week 12. RESULTS: Adjusting for group assignment, baseline RMDQ, age, and gender, foreign nationality and lower baseline SF36 physical component score (PCS) were independently associated with improvement in RMDQ. Greater than high school education level, cLBP less than 1 year, and lower baseline SF36 PCS were independently associated with improvement in pain intensity. Other demographics including race, income, gender, BMI, and use of pain medications were not associated with either outcome. CONCLUSIONS: Poor physical health at baseline is associated with greater improvement from yoga in back-related function and pain. Race, income, and body mass index do not affect the potential for a person with low back pain to experience benefit from yoga. AD - Boston University School of Medicine, USA ; Department of Family Medicine, University of Virginia Medical Center, USA. Department of Biostatistics, Boston University School of Public Health, USA. Group Health Research Institute, Group Health Cooperative, Seattle, WA and Department of Epidemiology, University of Washington, Seattle, WA, USA. Boston University School of Medicine, USA ; Department of Family Medicine, Boston University School of Medicine and Boston Medical Center, USA. Boston University School of Medicine, USA. AN - 25401042 AU - Stein, K. M. AU - Weinberg, J. AU - Sherman, K. J. AU - Lemaster, C. M. AU - Saper, R. C2 - PMC4228962 C6 - NIHMS604476 DA - Jan 11 DO - 10.4172/2157-7595.1000151 DP - NLM ET - 2014/11/18 IS - 1 KW - Alternative medicine Back pain Chronic pain Complementary medicine Hatha yoga Integrative medicine Low back pain Socioeconomic status Yoga LA - eng N1 - 2157-7595 Stein, Kim M Weinberg, Janice Sherman, Karen J Lemaster, Chelsey M Saper, Robert R01 AT005956/AT/NCCIH NIH HHS/United States Journal Article J Yoga Phys Ther. 2014 Jan 11;4(1):151. doi: 10.4172/2157-7595.1000151. PY - 2014 SN - 2157-7595 (Print) 2157-7595 SP - 151 ST - Participant Characteristics Associated with Symptomatic Improvement from Yoga for Chronic Low Back Pain T2 - J Yoga Phys Ther TI - Participant Characteristics Associated with Symptomatic Improvement from Yoga for Chronic Low Back Pain VL - 4 ID - 4093 ER - TY - JOUR AB - CASE: Jonny is a 13 year old boy with spastic quadriparesis and severe mental retardation following Haemophilus influenza type B (HIB) meningitis at 2-months of age. Signs of meningitis started on the evening of his 2-month immunizations that included the HIB vaccine. He presented to his pediatrician with left hip pain that occurred intermittently for a few years and more frequently in the past six months. His parents initially attributed the pain to whizzing around the back yard in a motorized wheelchair. An earlier evaluation of hip pain led to bilateral femoral osteotomies for hip dysplasia. Obesity, associated with inactivity and a tendency to consume fatty foods, complicates Jonny's disabilities. His only activity is a modest amount of physical therapy at school and "floor time" for about one hour each day at home. In the office of his pediatrician, Jonny is friendly, smiling, and verbalizing a few words with his limited expressive vocabulary. He is resistant to a hip examination and grimaces with manipulation of his left hip. Spasticity of the left leg appears increased compared to previous examinations. He has nonpitting edema of his lower legs and feet, a cryptorchid left testicle, and a somewhat tender left inguinal area. Jonny lives with his mother and father in a small house on a busy street less than one-half mile from the pediatrician's office. Jonny's pediatrician often sees him in his wheelchair, accompanied by his mother or grandmother, and waves or stops to chat. He has van services to school, and there is a Hoyer lift in the home, but his parents do not own a van. Recently, Jonny's father finds it more difficult to lift him. The family has also been challenged by the mental health problems of Jonny's two older brothers, and a serious eye injury suffered by his middle brother in a motor-vehicle accident. Jonny's pediatrician has cared for him and his two bothers since birth. Although the parents continue to believe that the HIB vaccine caused his catastrophic illness, they remain with the pediatrician. In general, they are satisfied with the individualized educational plan at a local public school. When he was 6.5 years old, Jonny's school aid reported that he attempted to touch her in the genital area. The pediatrician attended the meeting to review this incident and successfully advocated for Jonny by pointing out that this was an isolated incident; it did not occur again. At 6 years old Jonny functioned in the 1.5-2.5 year old range with motor skills in the 6-12 month level according to the Bayley Scales of Infant Development and the Vineland Adaptive Behavior Scales. In the past a neurologist and a physiatrist saw Jonny, but both of these individuals moved from the community. He had prior evaluations at a children's orthopedic clinic at a small community hospital and at the local Shriner's hospital. He had a tonsillectomy and adenoidectomy at 7 years old. He is currently treated for constipation and receives dental care at a clinic for people with disabilities. His pediatrician has always respected the parents for their care and obvious love for their disabled child. However, parental resistance to addressing major issues such as obesity has frustrated his pediatrician. When the pediatrician suggested that Jonny was eligible for the state's managed care program, which would convert Medicaid coverage to a state sponsored program with more extensive services and case management, Jonny's mother repeatedly said that she would "think it over." At the current visit, the pediatrician recommended an adjustment of Jonny's wheelchair, a hip x-ray, a referral to Shriner's Hospital, and an appointment with a pediatric surgeon to address the undescended testicle and possible hernia. Jonny's mother mentioned that he had been to Shriner's Hospital for hip pain two years earlier but was told nothing could be done "because nothing was wrong with his bone." The hip x-ray was normal as well as a complete blood count and a C-reactive protein. The pediatric surgeon did not find a hernia and deferred treatment of the cryptorchid testicle. His parents contacted the wheelchair company to arrange adjustments. The pediatrician called the medical director at the Shriner's Hospital to discuss Jonny's case, but 2 months after the initial visit, the parents had not arranged for an appointment at the Shriner's Hospital. Jonny's hip pain persisted. The pediatrician now wonders how he can more effectively address Jonny's current problems and improve overall care for him and his family. AN - WOS:000277185500024 AU - Stein, M. T. AU - Gottsegen, D. AU - Blasco, P. A. AU - Wolraich, M. AU - Hennessy, M. J. DA - Apr DO - 10.1097/DBP.0b013e3181d86e09 IS - 3 N1 - Stein, Martin T. Gottsegen, David Blasco, Peter A. Wolraich, Mark Hennessy, Michael J. S PY - 2010 SN - 0196-206X SP - S86-S91 ST - Chronic Hip Pain in a Boy With Mental Retardation and Cerebral Palsy T2 - Journal of Developmental and Behavioral Pediatrics TI - Chronic Hip Pain in a Boy With Mental Retardation and Cerebral Palsy UR - ://WOS:000277185500024 VL - 31 ID - 2559 ER - TY - JOUR AB - Report of chronic headache amongst children with shunted hydrocephalus is frequent, and often leads to investigation for raised intra-cranial pressure and shunt malfunction, and much debate has appeared in the literature concerning possible cause. However headache is a common neurological symptom amongst children, and studies of prevalence indicate incidence of frequent non-migrainous headache to be 6.8%, and migrainous headache 4% in the general child population. A relationship between stress and anxiety and headache is recognised, and the hydrocephalic child has many reasons above those of his/her peers to be subject to stress. It is also hypothesised that this group may be more vulnerable than peers to developing a migraine-like condition in the face of adequate shunt function. The clinician dealing with complaint of chronic headache in a hydrocephalic child must therefore be wary of over-investigation in a child with a working shunt, or missing possible shunt malfunction when the only symptom is chronic headache. It was speculated therefore that incidence of non-shunt related chronic headache in this group would be high, and an attempt was made to document incidence of migrainous and non-migrainous headache in the medical notes, and in replies to postal questionnaire sent to a sample of 130 children with shunted hydrocephalus of varying aetiology. Incidence of migrainous headache was documented in the medical notes in 8.5% of cases, with incidence rising to 21.5% using self-report. Incidence of non-migrainous headache was also very high (15.4%) and the overlap between migraine and tension headache, combined with difficulty of diagnosis in children may indicate migraine to be more frequent still. The concept of "Shunt Migraine" is therefore worthy of consideration. Report of chronic headache led to investigation in a large proportion of cases, but symptomatology often continued. Even when shunt malfunction was indicated, shunt revision did not "cure" complaint of headache. Headache was not found to be related to diagnosis associated with hydrocephalus, to presence of seizure disorder, or to the sex of the child, although in common with other studies, there was a strong trend towards girls being statistically more likely to experience headache than boys. There was a relationship however between report of chronic headache, and the sort of school a child was likely to attend; children who attended mainstream school without the support of a Statement of Special Educational Need were more likely to report headache than their peers, and it is hypothesised that these children may be suffering sufficient stress to contribute to maintenance of headache. The importance of the multi-disciplinary team in assessment of children's physical, intellectual and emotional status is stressed, in order that medical interventions have the greatest chance of success. AN - WOS:000072150400004 AU - Stellman-Ward, G. R. AU - Bannister, C. M. AU - Lewis, M. A. AU - Shaw, J. DA - Dec DO - 10.1055/s-2008-1071201 N1 - Stellman-Ward, GR Bannister, CM Lewis, MA Shaw, J 41st Annual Meeting of the Society-for-Research-into-Hydrocephalus-and-Spina-Bifida 1997 Manchester, england Soc Res Hydrocephalus & Spina Bifida 1439-359x 1 PY - 1997 SN - 0939-7248 SP - 12-14 ST - The incidence of chronic headache in children with shunted hydrocephalus T2 - European Journal of Pediatric Surgery TI - The incidence of chronic headache in children with shunted hydrocephalus UR - ://WOS:000072150400004 VL - 7 ID - 2901 ER - TY - JOUR AB - Background: Recurrent headache is the most common and disabling pain condition in adolescence. Co-occurrence of psychosocial adversity is associated with increased risk of chronification and functional impairment. Exposure to interpersonal violence seems to constitute an important etiological factor. Thus, knowledge of the multiple pathways linking interpersonal violence to recurrent headache could help guide preventive and clinical interventions. In the present study we explored a hypothetical causal model where the link between exposure to interpersonal violence and recurrent headache is mediated in parallel through loneliness and psychological distress. Higher level of family cohesion and male sex is hypothesized to buffer the adverse effect of exposure to interpersonal violence on headache. Methods: The model was assessed using data from the cross-sectional, population-based Young-HUNT 3 study of Norwegian adolescents, conducted from 2006-2008. A cohort of 10 464 adolescents were invited. The response rate was 73% (7620), age ranged from 12 and 20 years, and 50% (3832) were girls. The study comprised self-report measures of exposure to interpersonal violence, loneliness, psychological distress and family cohesion, in addition to a validated interview on headache, meeting the International Classification of Headache Disorders criteria. Recurrent headache was defined as headache recurring at least monthly during the past year, and sub-classified into monthly and weekly headache, which served as separate outcomes. Results: In Conditional Process Analysis, loneliness and psychological distress consistently posed as parallel mediating mechanisms, indirectly linking exposure to interpersonal violence to recurrent headache. We found no substantial moderating effect of family cohesion or sex. Conclusions: Loneliness and psychological distress seem to play crucial roles in the relationship between exposure to interpersonal violence and recurrent headache. To facilitate coping and recovery, it may be helpful to account for these factors in preventive and clinical interventions. Trauma-informed, social relationship-based interventions may represent a major opportunity to alter trajectories of recurrent headache. AN - WOS:000347986500001 AU - Stensland, S. O. AU - Thoresen, S. AU - Wentzel-Larsen, T. AU - Zwart, J. A. AU - Dyb, G. C7 - 35 DA - Jun DO - 10.1186/1129-2377-15-35 N1 - Stensland, Synne Oien Thoresen, Siri Wentzel-Larsen, Tore Zwart, John-Anker Dyb, Grete 1129-2377 PY - 2014 SN - 1129-2369 ST - Recurrent headache and interpersonal violence in adolescence: the roles of psychological distress, loneliness and family cohesion: the HUNT study T2 - Journal of Headache and Pain TI - Recurrent headache and interpersonal violence in adolescence: the roles of psychological distress, loneliness and family cohesion: the HUNT study UR - ://WOS:000347986500001 VL - 15 ID - 2304 ER - TY - JOUR AB - Objective: Functional dystonia (FD) is a disabling and diagnostically challenging functional movement disorder (FMD). We sought to identify historical predictors of FD vs. other primary dystonias (ODs) and develop a practical prediction algorithm to guide neurologists. Methods: 1475 consecutive new patient medical records were reviewed at an adult/pediatric tertiary-referral dystonia clinic from 2005 to 2017. Ninety-nine met criteria for clinically established FD (85 adults and 14 pediatric), paired with 99 age/dystonia distribution-matched OD. Univariate and multivariate regression analyses were performed to identify predictors of FD and disability. We formed a prediction algorithm, assessed using the area under the receiver operating curve (AUC). Results: Multivariate logistic regression analysis investigating independent predictors of FD (P < 0.001) followed by development of a prediction algorithm showed that the most robust predictors included abrupt onset, spontaneous resolution/recurrence, pain, cognitive complaints, being on or pursuing disability, lifetime mood/anxiety disorder, comorbid functional somatic disorders, and having >= 3 medication allergies. The prediction algorithm had utility for both adult and pediatric FD, with excellent sensitivity/specificity (89%/92%) and an area under the curve (AUC) 0.95 (0.92-0.98). Greater disability (modified Rankin Scale) independently correlated with a number of functional examination features, unemployment/not attending school, number of medication allergies, and younger age of presentation. FD patients were high health-care utilizers and were more frequently prescribed opiates/opioids and benzodiazepines (P < 0.003). Interpretation: This case-control study provides an algorithm to guide clinicians in gauging their index of suspicion for a FD, with diagnostic confirmation subsequently informed by neurological examination. While this algorithm requires prospective validation, health-care utilization data underscore the importance and need for more research in FD. AN - WOS:000629303400001 AU - Stephen, C. D. AU - Perez, D. L. AU - Chibnik, L. B. AU - Sharma, N. DA - Apr DO - 10.1002/acn3.51307 IS - 4 N1 - Stephen, Christopher D. Perez, David L. Chibnik, Lori B. Sharma, Nutan Perez, David/0000-0003-2721-583X PY - 2021 SN - 2328-9503 SP - 732-748 ST - Functional dystonia: A case-control study and risk prediction algorithm T2 - Annals of Clinical and Translational Neurology TI - Functional dystonia: A case-control study and risk prediction algorithm UR - ://WOS:000629303400001 VL - 8 ID - 1748 ER - TY - JOUR AB - Measuring patient satisfaction scores and interpreting factors that impact their variation is of importance as scores influence various aspects of health care administration. Our objective was to evaluate if Press Ganey scores differ between medical specialties.New patient visits between January 2014 and December 2016 at a single tertiary academic center were included in this study. Press Ganey scores were compared between specialties using a multivariable logistic mixed effects model. Secondary outcomes included a comparison between surgical versus non-surgical specialties, and pediatric versus adult specialties. Due to the survey's high ceiling effect, satisfaction was defined as a perfect total score.Forty four thousand four hundred ninety six patients met inclusion criteria. Compared to internal medicine, plastic surgery, general surgery, dermatology, and family medicine were more likely to achieve a perfect overall score, as, with odds ratios of 1.46 (P = .02), 1.29 (P = .002), 1.22 (P = .004), and 1.16 (P = .02) respectively. Orthopaedics, pediatric medicine, pediatric neurology, neurology, and pain management were less likely to achieve satisfaction with odds ratios of 0.85 (P = .047), 0.71 (P < .001), 0.63 (P = .005), 0.57 (P < .001), and 0.51 (P = .006), respectively. Compared to pediatric specialties, adult specialties were more likely to achieve satisfaction (OR 1.73; P < .001). There were no significant differences between surgical versus non-surgical specialties.Press Ganey scores systematically differ between specialties within the studied institution. These differences should be considered by healthcare systems that use patient satisfaction data to modify provider reimbursement. AD - Department of Orthopaedics, University of Utah, 590 Wakara Way. University of Utah, School of Medicine, 30N 1900E. University of Utah, Division of Public Health, 375 Chipeta Way, Salt Lake City, UT. AN - 33761706 AU - Stephens, A. R. AU - Presson, A. P. AU - Chen, D. AU - Tyser, A. R. AU - Kazmers, N. H. DA - Mar 26 DO - 10.1097/md.0000000000025211 DP - NLM ET - 2021/03/26 IS - 12 KW - Adult Age Factors Aged Data Collection Female Health Care Surveys Humans Male *Medicine/classification/statistics & numerical data Outpatients/*statistics & numerical data Patient Reported Outcome Measures Patient Satisfaction/*statistics & numerical data Quality of Health Care/standards Research Design United States LA - eng N1 - 1536-5964 Stephens, Andrew R Orcid: 0000-0003-3877-7723 Presson, Angela P Chen, Danli Tyser, Andrew R Kazmers, Nikolas H UL1TR002538/TR/NCATS NIH HHS/United States UL1TR002538/RR/NCRR NIH HHS/United States Journal Article United States Medicine (Baltimore). 2021 Mar 26;100(12):e25211. doi: 10.1097/MD.0000000000025211. PY - 2021 SN - 0025-7974 SP - e25211 ST - Inter-specialty variation of the Press Ganey Outpatient Medical Practice Survey T2 - Medicine (Baltimore) TI - Inter-specialty variation of the Press Ganey Outpatient Medical Practice Survey VL - 100 ID - 4198 ER - TY - JOUR AB - PURPOSE/OBJECTIVES: To compare the effects of partner-delivered foot reflexology and usual care plus attention on patients' perceived pain and anxiety. DESIGN: The experimental pretest/post-test design included patient-partner dyads randomly assigned to an experimental or control group. SETTING: Four hospitals in the southeastern United States. SAMPLE: 42 experimental and 44 control subjects comprised 86 dyads of patients with metastatic cancer and their partners, representing 16 different types of cancer; 23% of patients had lung cancer, followed by breast, colorectal, and head and neck cancer and lymphoma. The subjects had a mean age of 58.3 years, 51% were female, 66% had a high school education or less, and 58% were Caucasian, 40% were African American, and 1% were Filipino. METHODS: The intervention included a 15- to 30-minute teaching session on foot reflexology to the partner by a certified reflexologist, an optional 15- to 30-minute foot reflexology session for the partner, and a 30-minute, partner-delivered foot reflexology intervention for the patient. The control group received a 30-minute reading session from their partners. MAIN RESEARCH VARIABLES: Pain and anxiety. FINDINGS: Following the initial partner-delivered foot reflexology, patients experienced a significant decrease in pain intensity and anxiety. CONCLUSIONS: A nurse reflexologist taught partners how to perform reflexology on patients with metastatic cancer pain in the hospital, resulting in an immediate decrease in pain intensity and anxiety; minimal changes were seen in the control group, who received usual care plus attention. IMPLICATIONS FOR NURSING: Hospitals could have qualified professionals offer reflexology as a complementary therapy and teach interested partners the modality. AD - School of Nursing, East Carolina University, Greenville, NC, USA. stephensonn@mail.ecu.edu AN - 17562639 AU - Stephenson, N. L. AU - Swanson, M. AU - Dalton, J. AU - Keefe, F. J. AU - Engelke, M. DA - Jan DO - 10.1188/07.Onf.127-132 DP - NLM ET - 2007/06/15 IS - 1 KW - Anxiety/diagnosis/etiology/psychology/*rehabilitation Female Humans Male Massage/methods/*psychology Middle Aged Neoplasm Metastasis Neoplasms/*complications Pain/diagnosis/etiology/psychology/*rehabilitation Pain Measurement Spouses/*psychology LA - eng N1 - 1538-0688 Stephenson, Nancy L N Swanson, Melvin Dalton, Joann Keefe, Frances J Engelke, Martha R21 CA105432/CA/NCI NIH HHS/United States Journal Article Randomized Controlled Trial Research Support, N.I.H., Extramural United States Oncol Nurs Forum. 2007 Jan;34(1):127-32. doi: 10.1188/07.ONF.127-132. PY - 2007 SN - 0190-535x SP - 127-32 ST - Partner-delivered reflexology: effects on cancer pain and anxiety T2 - Oncol Nurs Forum TI - Partner-delivered reflexology: effects on cancer pain and anxiety VL - 34 ID - 4182 ER - TY - JOUR AB - Objective: To assess the baseline global health status and quality of life (QOL) in children with tonsil and adenoid disease. Design: Cross-sectional multicenter survey series. Settings: A tertiary academic pediatric specialty hospital and a tertiary academic hospital in 2 different cities. Patients and Other Participants: Consecutive series of 55 parents of children who were seen for tonsil and adenoid disease. Intervention and Method: Cross-sectional survey of the health status of affected children to assess their QOL and its relationship to tonsil and adenoid disease. Main Outcome Measures: Quality-of-life subscale scores: of affected children on the Child Health Questionnaire version PF28 (CHQ-PF28); comparisons of population data from healthy normal children and children with asthma and juvenile rheumatoid arthritis. Results: The overall health status and QOL of children with tonsil and adenoid disease is significantly worse than those of healthy normal children, as demonstrated by lower mean scores on several CHQ-PF28 subscales, including general health, physical functioning, behavior, bodily pain, and parental impact (emotional). In addition, the general health perception of children with tonsil and adenoid disease is similar to the perceptions of children with asthma and juvenile rheumatoid arthritis, but several aspects of health status, as measured by CHQ-PF28 subscale scores, were significantly worse in children with tonsil and adenoid disease. Conclusion: The health status impact of tonsil and adenoid disease appears to be quite significant, particularly in aspects related to the parental impact of the child's disease. AN - WOS:000084630700008 AU - Stewart, M. G. AU - Friedman, E. M. AU - Sulek, M. AU - Hulka, G. F. AU - Kuppersmith, R. B. AU - Harrill, W. C. AU - Bautista, M. H. DA - Jan DO - 10.1001/archotol.126.1.45 IS - 1 N1 - Stewart, MG Friedman, EM Sulek, M Hulka, GF Kuppersmith, RB Harrill, WC Bautista, MH 13th Annual Meeting of the American-Society-of-Pediatric-Otolaryngology May 12-14, 1998 Palm beach, florida Amer Soc Pediatr Otolaryngol Harrill, MD FACS, Willard/0000-0003-4782-1343 PY - 2000 SN - 0886-4470 SP - 45-48 ST - Quality of life and health status in pediatric tonsil and adenoid disease T2 - Archives of Otolaryngology-Head & Neck Surgery TI - Quality of life and health status in pediatric tonsil and adenoid disease UR - ://WOS:000084630700008 VL - 126 ID - 2871 ER - TY - JOUR AB - In a population-based telephone interview survey of 9,380 residents aged 12 to 29 yr in Washington County, Maryland, who reported having had a headache, 60% of females and 41% of males had had one or more headaches during the previous week; 14.4% of females and 6.0% of males in the study group had consulted a physician in the previous 12 months for a headache problem. The likelihood of consulting a physician differed according to the type of headache. Subjects with headache during the week before the interview meeting the criteria for certain migraine or certain mixed tension--migraine were twice as likely as subjects with all other types of headaches to consult a physician during the previous 12 months. Females with tension headache were considerably more likely than males with the tension headache to have consulted a physician during the previous 12 months. On the other hand, males with migraine headache during the previous week were more likely than females with migraine to consult a physician. Disability (defined as being absent from school or from work for all or part of the day) was relatively common among those subjects with a headache during the previous week (13.7% of females and 7.9% of males). However, even among those reporting disability as a result of their headache during the previous week, only 31% of females and 18% of males reported consulting a physician during the previous 12 months.(ABSTRACT TRUNCATED AT 250 WORDS) AD - Department of Epidemiology, Johns Hopkins University School of Hygiene and Public Health, Baltimore, MD. AN - 2640911 AU - Stewart, W. F. AU - Celentano, D. D. AU - Linet, M. S. DO - 10.1016/0753-3322(89)90159-5 DP - NLM ET - 1989/01/01 IS - 10 KW - *Absenteeism Adolescent Adult Age Factors Child Drug Prescriptions/*statistics & numerical data Female Headache/drug therapy/*epidemiology Humans Male Maryland Migraine Disorders/drug therapy/epidemiology Patient Acceptance of Health Care/*statistics & numerical data Random Allocation Sex Factors LA - eng N1 - Stewart, W F Celentano, D D Linet, M S NS 19381/NS/NINDS NIH HHS/United States Journal Article Research Support, U.S. Gov't, P.H.S. France Biomed Pharmacother. 1989;43(10):711-8. doi: 10.1016/0753-3322(89)90159-5. PY - 1989 SN - 0753-3322 (Print) 0753-3322 SP - 711-8 ST - Disability, physician consultation, and use of prescription medications in a population-based study of headache T2 - Biomed Pharmacother TI - Disability, physician consultation, and use of prescription medications in a population-based study of headache VL - 43 ID - 3445 ER - TY - JOUR AB - Data from population-based studies are summarized to characterize the full range and variability of the impact migraine has on the individual. Despite differences in methods and data collection in population-based studies describing disability, pain intensity, and attack frequency as well as the duration of migraine and other headaches, several patterns emerge. On average, migraine headaches are more disabling, more painful, and longer in duration than other types of headaches. Females report more pain and disability with headache than do males. Although disability measurements are important in demonstrating the effect of headache on both the individual and society, actual measurements often fall short. Most studies use only workdays lost as the sole measure of disability. Most migraineurs do not miss work while experiencing a headache; instead, they attempt to function on the job, with considerably reduced effectiveness. Computing only workdays lost does not account for impairment at work nor does it show the impact of migraine on other aspects of life. In addition, evidence suggests the presence of a pain intensity threshold for disability. Headache-related pain intensity below the threshold is not associated with disability. Despite the threshold of pain intensity for disability, a significant proportion of migraine sufferers report levels of pain intensity above the threshold in the absence of work-related disability. The grading of headache severity should be a composite that would permit a more complete image of the heterogeneity of migraine's effects and a more accurate idea of the need for healthcare services. This composite should include two areas: (1) more complete measures of life impact, encompassing daily activities in a number of domains, including work, family, and social activities; and (2) an assessment of pain intensity and attack frequency. AN - WOS:A1994NU44200005 AU - Stewart, W. F. AU - Schechter, A. AU - Lipton, R. B. DA - Jun IS - 6 N1 - Stewart, wf schechter, a lipton, rb Symposium on the Impact of Migraine Jan 28-31, 1993 Coral gables, fl Lipton, Richard B/B-5060-2011 4 PY - 1994 SN - 0028-3878 SP - 24-39 ST - MIGRAINE HETEROGENEITY - DISABILITY, PAIN INTENSITY, AND ATTACK FREQUENCY AND DURATION T2 - Neurology TI - MIGRAINE HETEROGENEITY - DISABILITY, PAIN INTENSITY, AND ATTACK FREQUENCY AND DURATION UR - ://WOS:A1994NU44200005 VL - 44 ID - 2948 ER - TY - JOUR AB - BACKGROUND: Pain is one of the most common and distressing symptoms reported by adolescents with cancer. Despite advancements in pain assessment and management research, pain due to cancer and/or its treatments continues to be poorly managed. Our research group has developed a native iPhone application (app) called Pain Squad to tackle the problem of poorly managed pain in the adolescent with cancer group. The app functions as an electronic pain diary and is unique in its ability to collect data on pain intensity, duration, location, and the impact pain has on an adolescent's life (ie, relationships, school work, sleep, mood). It also evaluates medications and other physical and psychological pain management strategies used. Users are prompted twice daily at configurable times to complete 20 questions characterizing their pain and the app transmits results to a database for aggregate reporting through a Web interface. Each diary entry represents a pain case filed by an adolescent with cancer and a reward system (ie, moving up through law-enforcement team ranks, built-in videotaped acknowledgements from fictitious officers) encourages consistent use of the diary. OBJECTIVE: Our objective was to design, develop, and test the usability, feasibility, compliance, and satisfaction of a game-based smartphone pain assessment tool for adolescents with cancer. METHODS: We used both low- and high-fidelity qualitative usability testing with qualitative semi-structured, audio-taped interviews and iterative cycles to design and refine the iPhone based Pain Squad app. Qualitative thematic analysis of interviews using constant comparative methodology captured emergent themes related to app usability. Content validity was assessed using question importance-rating surveys completed by participants. Compliance and satisfaction data were collected following a 2-week feasibility trial where users were alarmed to record their pain twice daily on the app. RESULTS: Thematic analysis of usability interviews showed the app to be appealing overall to adolescents. Analyses of both low- and high-fidelity testing resulted in minor revisions to the app to refine the theme and improve its usability. Adolescents resoundingly endorsed the game-based nature of the app and its virtual reward system. The importance of app pain diary questions was established by content validity analysis. Compliance with the app, assessed during feasibility testing, was high (mean 81%, SD 22%) and adolescents from this phase of the study found the app likeable, easy to use, and not bothersome to complete. CONCLUSIONS: A multifaceted usability approach demonstrated how the Pain Squad app could be made more appealing to children and adolescents with cancer. The game-based nature and built-in reward system of the app was appealing to adolescents and may have resulted in the high compliance rates and satisfaction ratings observed during clinical feasibility testing. AD - The Hospital for Sick Children, Toronto, ON, Canada. jennifer.stinson@sickkids.ca AN - 23475457 AU - Stinson, J. N. AU - Jibb, L. A. AU - Nguyen, C. AU - Nathan, P. C. AU - Maloney, A. M. AU - Dupuis, L. L. AU - Gerstle, J. T. AU - Alman, B. AU - Hopyan, S. AU - Strahlendorf, C. AU - Portwine, C. AU - Johnston, D. L. AU - Orr, M. C2 - PMC3636147 DA - Mar 8 DO - 10.2196/jmir.2350 DP - NLM ET - 2013/03/12 IS - 3 KW - Adolescent *Cell Phone Feasibility Studies Female Humans Male *Microcomputers Neoplasms/*complications Pain/*etiology/physiopathology Pain Measurement/*methods Patient Compliance Patient Satisfaction LA - eng N1 - 1438-8871 Stinson, Jennifer N Jibb, Lindsay A Nguyen, Cynthia Nathan, Paul C Maloney, Anne Marie Dupuis, L Lee Gerstle, J Ted Alman, Benjamin Hopyan, Sevan Strahlendorf, Caron Portwine, Carol Johnston, Donna L Orr, Mike Journal Article Research Support, Non-U.S. Gov't J Med Internet Res. 2013 Mar 8;15(3):e51. doi: 10.2196/jmir.2350. PY - 2013 SN - 1439-4456 (Print) 1438-8871 SP - e51 ST - Development and testing of a multidimensional iPhone pain assessment application for adolescents with cancer T2 - J Med Internet Res TI - Development and testing of a multidimensional iPhone pain assessment application for adolescents with cancer VL - 15 ID - 4102 ER - TY - JOUR AB - IMPORTANCE: Monitoring trends in prescription analgesic use among adults with musculoskeletal conditions provides insight into how changing prescribing practices, guidelines, and policy measures may affect those who need pain management. OBJECTIVE: To evaluate trends in prescription opioid use and nonopioid analgesic use among adults with functional limitations attributable to musculoskeletal conditions. DESIGN, SETTING, AND PARTICIPANTS: This repeated cross-sectional study uses data from the National Health and Nutrition Examination Study from 1999 to 2016. Data were analyzed from January to July 2019. The participants were adults aged 30 to 79 years who reported functional limitations due to back or neck problems and/or arthritis or rheumatism. MAIN OUTCOMES AND MEASURES: Any use of a prescription opioid or exclusive use of a prescription nonopioid analgesic. RESULTS: In this population of 7256 adults with 1 or more functional limitations attributable to a musculoskeletal condition (4226 women [59.9%]; 3508 [74.4%] non-Hispanic white individuals; median [interquartile range] age, 63 [53-70] years), opioid use and exclusive nonopioid analgesic use exhibited approximately reciprocal patterns of change from 1999 to 2016. Opioid use increased significantly (difference in prevalence for 2015-2016 vs 1999-2000, 7.2%; 95% CI, 1.3% to 13%; P for trend = .002), and exclusive use of nonopioid analgesics decreased significantly (difference in prevalence for 2015-2016 vs 1999-2000, -13%; 95% CI, -19% to -7.5%; P for trend < .001) during this period. The increase in any opioid use was driven by long-term rather than short-term use. A crossover in the prevalence of opioid use and exclusive use of nonopioid analgesics occurred between 2003 and 2006, after which opioid use was more prevalent. Between 2013 and 2016, decreases in opioid use were observed among men (difference in prevalence for 2015-2016 vs 2013-2014, -11%; 95% CI, -21% to 1.8%) and participants with less than a high school education (difference, -15%; 95% CI, -24% to -6.1%). During this same period, exclusive nonopioid analgesic use also decreased markedly across the population (difference, -5.3%; 95% CI, -9.1% to -1.5%). CONCLUSIONS AND RELEVANCE: The substitution of opioids for nonopioid analgesics between 2003 and 2006 may have occurred as evidence emerged on the cardiovascular risks associated with nonopioid analgesics. Reductions in opioid use between 2013 and 2016 were most substantial among those with low socioeconomic status, who may encounter barriers in accessing alternatives. Despite those decreases, opioid use remained more prevalent in 2015 to 2016 than in 1999 to 2000, suggesting a potentially long tail for the opioid epidemic. AD - Department of Global Health, Boston University School of Public Health, Boston, Massachusetts. Division of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis. Robert Wood Johnson Foundation, Princeton, New Jersey. Department of Medicine, Boston University School of Medicine, Boston, Massachusetts. Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts. AN - 31825504 AU - Stokes, A. AU - Berry, K. M. AU - Hempstead, K. AU - Lundberg, D. J. AU - Neogi, T. C2 - PMC6991204 Ethicon Endo-Surgery outside of the submitted work. Dr Neogi reported receiving personal fees from Pfizer and Regeneron. No other disclosures were reported. DA - Dec 2 DO - 10.1001/jamanetworkopen.2019.17228 DP - NLM ET - 2019/12/12 IS - 12 KW - Adult Aged Analgesics/*therapeutic use Analgesics, Opioid/therapeutic use Cross-Sectional Studies Drug Utilization/*trends Female Humans Male Middle Aged Musculoskeletal Pain/*drug therapy Nutrition Surveys Opioid Epidemic Practice Patterns, Physicians'/*trends United States/epidemiology LA - eng N1 - 2574-3805 Stokes, Andrew Berry, Kaitlyn M Hempstead, Katherine Lundberg, Dielle J Neogi, Tuhina K24 AR070892/AR/NIAMS NIH HHS/United States P2C HD041023/HD/NICHD NIH HHS/United States P30 AR072571/AR/NIAMS NIH HHS/United States T32 HD095134/HD/NICHD NIH HHS/United States Journal Article Observational Study Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't JAMA Netw Open. 2019 Dec 2;2(12):e1917228. doi: 10.1001/jamanetworkopen.2019.17228. PY - 2019 SN - 2574-3805 SP - e1917228 ST - Trends in Prescription Analgesic Use Among Adults With Musculoskeletal Conditions in the United States, 1999-2016 T2 - JAMA Netw Open TI - Trends in Prescription Analgesic Use Among Adults With Musculoskeletal Conditions in the United States, 1999-2016 VL - 2 ID - 4223 ER - TY - JOUR AB - A girl, born in 1973, started having headache in preschool age. After a head trauma in 1985, there was a clear worsening of the headache, and the headache became chronic at around 14 years, making regular school attendance impossible. The headache was ''symptom poor,'' bilateral-occipital, but with a clear left-sided preponderance and occasionally spreading to the forehead. The headache was always worst in the morning hours, easing up by noontime. Neck rotation to the right could provoke long-lasting exacerbations. Neck movement was restricted on rotation to the left. A sore bony structure was discovered on palpation just underneath the mastoid process of the left side. This proved to correspond to a bony ''bridge'' with an extra joint between the first vertebra on the left side and the skull, medially to the mastoid process that could be demonstrated on x-ray tomography and CT scanning. This bony bridge was removed surgically more than 2 years ago, and the pain disappeared on the day of operation and has not recurred in the intervening time. Such bony bridges have in the past been considered to be innocuous and not symptom producing. Although this may be the general rule, the present case tends to show that even to this rule, there are exceptions. AN - WOS:A1995QF33800011 AU - Stoltnielsen, A. AU - Fredriksen, T. A. AU - Sjaastad, O. DA - Jan DO - 10.1111/j.1526-4610.1995.hed3501044.x IS - 1 N1 - Stoltnielsen, a fredriksen, ta sjaastad, o PY - 1995 SN - 0017-8748 SP - 44-47 ST - HEADACHE DUE TO AN EXTRA JOINT BETWEEN HEAD AND NECK T2 - Headache TI - HEADACHE DUE TO AN EXTRA JOINT BETWEEN HEAD AND NECK UR - ://WOS:A1995QF33800011 VL - 35 ID - 2941 ER - TY - JOUR AB - To explore the long-term prognosis for children referred for recurrent abdominal pain (RAP), 44 children investigated for RAP 5 y ago were compared to a group of controls (n = 88). The former RAP patients reported RAP, headache and school absence more frequently than controls. Conclusion: A high proportion of children referred with RAP have persistent symptoms, with more headache and school absence than controls. The diagnostic subgroup did not predict persistence of abdominal pain. AN - WOS:000227783700021 AU - Stordal, K. AU - Nygaard, E. A. AU - Bentsen, B. S. DA - Feb DO - 10.1080/08035250410025104 IS - 2 N1 - Stordal, K Nygaard, EA Bentsen, BS 1651-2227 PY - 2005 SN - 0803-5253 SP - 234-236 ST - Recurrent abdominal pain: A five-year follow-up study T2 - Acta Paediatrica TI - Recurrent abdominal pain: A five-year follow-up study UR - ://WOS:000227783700021 VL - 94 ID - 2773 ER - TY - JOUR AB - BACKGROUND CONTEXT: To date, most reports on the incidence of adverse events (AEs) in spine surgery have been retrospective and dependent on data abstraction from hospital-based administrative databases. To our knowledge, there have been no previous rigorously performed prospective analysis of all AEs occurring in the entire population of patients presenting to an academic quaternary referral center. PURPOSE: To determine the mortality and true incidence and severity of morbidity (major and minor, medical and surgical) in adults undergoing complex spinal surgery, both trauma and elective, in a quaternary referral center. To examine the influence of the introduction of a dedicated weekly multidisciplinary rounds, and a formal abstraction tool, on the recording of this prospective perioperative morbidity data. To examine the validity and inter- and intraobserver reliability of a dedicated Spine AdVerse Events Severity system, version 2 (SAVES V2) AE abstraction tool. STUDY DESIGN: Ours is an academic quaternary referral center serving a population of 4.5 million people. Beginning in April 2008, a spine-specific AE-recording instrument, entitled SAVES V2, was introduced at our center for reporting, categorization, and classification of AEs. The use of this system remains an ongoing prospective study. PATIENT SAMPLE: All adult patients admitted to the spine service of a quaternary referral center for a 12-month period. OUTCOME MEASURES: A validity and an inter- and intraobserver reliability examination of the SAVES V2 system, as used at our institution. Morbidity and inhospital deaths, unplanned second surgeries during index admission, wound infections requiring reoperation, and readmissions during the same calendar year. We also examined in detail all intraoperative and nonsurgical postoperative AEs, as well as hospital length of stay (LOS). METHODS: Data on all patients undergoing surgery over a 12-month period were prospectively collected using a perioperative morbidity abstraction tool at weekly dedicated mortality and morbidity rounds. This tool allows identification of each specific AE and grades the severity. Before the introduction of this system, and using the hospital inpatient database, our documented perioperative morbidity rate (major and minor, medical and surgical) was 23%. Diagnosis, operative data, hospital data, major and minor complications both medical and surgical, and deaths were recorded. RESULTS: One hundred percent of all patients discharged from the unit had complete data available for analysis. Nine hundred forty-two patients with an age range of 16 to 90 years (mean, 54 years; mode, 38 years) were identified. There were 552 males and 390 females. Around 58.5% of patients had undergone elective surgery. Thirty percent of patients were American Spinal Injury Association class D or worse on admission. The average LOS was 13.5 days (range, 1-221 days). Eight hundred twenty-two (87%) patients had at least one documented complication. Thirty-nine percent of these adversely affected hospital LOS. There were 14 mortalities during the study period. The rate of intraoperative surgical complication was 10.5% (4.5% incidental durotomy and 1.9% hardware malposition requiring revision and 2.2% blood loss >2 L). The incidence of postoperative complication was 73.5% (wound complications, 13.5%; delerium, 8%; pneumonia, 7%; neuropathic pain, 5%; dysphagia, 4.5%; and neurological deterioration, 3%). CONCLUSIONS: Major spinal surgery in the adult is associated with a high incidence of intra- and postoperative complications. We identified a very high rate of previously unrecognized postoperative complications, which adversely affect LOS. Without strict adherence to a prospective data collection system, the true complexity of this surgery may be greatly underestimated. AD - Combined Neurosurgical and Orthopedic Spine Program, Vancouver General Hospital, University of British Columbia, Floor 6, Blusson Spinal Cord Center, 818 West 10th Ave., Vancouver, British Columbia, Canada. john.street@vch.ca AN - 22209243 AU - Street, J. T. AU - Lenehan, B. J. AU - DiPaola, C. P. AU - Boyd, M. D. AU - Kwon, B. K. AU - Paquette, S. J. AU - Dvorak, M. F. AU - Rampersaud, Y. R. AU - Fisher, C. G. DA - Jan DO - 10.1016/j.spinee.2011.12.003 DP - NLM ET - 2012/01/03 IS - 1 KW - Adolescent Adult Aged Aged, 80 and over Canada Cohort Studies Female Humans Incidence Intraoperative Complications/*epidemiology Length of Stay Male Middle Aged Orthopedic Procedures/*adverse effects/*mortality Postoperative Complications/*epidemiology Spine/*surgery Young Adult LA - eng N1 - 1878-1632 Street, John T Lenehan, Brian J DiPaola, Christian P Boyd, Michael D Kwon, Brian K Paquette, Scott J Dvorak, Marcel F S Rampersaud, Y Raja Fisher, Charles G Journal Article United States Spine J. 2012 Jan;12(1):22-34. doi: 10.1016/j.spinee.2011.12.003. Epub 2011 Dec 29. PY - 2012 SN - 1529-9430 SP - 22-34 ST - Morbidity and mortality of major adult spinal surgery. A prospective cohort analysis of 942 consecutive patients T2 - Spine J TI - Morbidity and mortality of major adult spinal surgery. A prospective cohort analysis of 942 consecutive patients VL - 12 ID - 4146 ER - TY - JOUR AB - Background: Although caffeine is the most widely used mood-altering drug in the world, few studies have operationalized and characterized Diagnostic and Statistical Manual IV (DSM-IV) substance dependence criteria applied to caffeine. Methods: As a part of a nosological study of substance use disorders funded by the National Institute on Drug Abuse, we assessed caffeine use and dependence symptoms among high school and college students, drug treatment patients, and pain clinic patients who reported caffeine use in the last 7 days and also reported use of alcohol, nicotine, or illicit drugs within the past year (n=167). Results: Thirty-five percent met the criteria for dependence when all seven of the adopted DSM dependence criteria were used. Rates of endorsement of several of the most applicable diagnostic criteria were as follows: 26% withdrawal, 23% desire to cut down or control use, and 44% continued use despite harm. In addition, 34% endorsed craving, 26% said they needed caffeine to function, and 10% indicated that they talked to a physician or counselor about problems experienced with caffeine. There was a trend towards increased caffeine dependence among those dependent on nicotine or alcohol. Within a subgroup that had used caffeine, alcohol, and nicotine in the past year, 28% fulfilled criteria for caffeine dependence compared to 50% for alcohol and 80% for nicotine. Conclusion: The present study adds to a growing literature suggesting the reliability, validity, and clinical utility of the caffeine dependence diagnosis. Recognition of caffeine dependence in the DSM-V may be clinically useful. AD - Department of Epidemiology, College of Public Health and Health Professions, College of Medicine, University of Florida , Gainesville, Florida. Department of Psychiatry and Behavioral Sciences, Department of Neuroscience, Johns Hopkins University School of Medicine , Baltimore, Maryland. AN - 24761264 AU - Striley, C. L. AU - Griffiths, R. R. AU - Cottler, L. B. C2 - PMC3621326 DA - Dec DO - 10.1089/jcr.2011.0029 DP - NLM ET - 2011/12/01 IS - 4 LA - eng N1 - 2156-5368 Striley, Catherine L W Griffiths, Roland R Cottler, Linda B R01 DA003890/DA/NIDA NIH HHS/United States Journal Article J Caffeine Res. 2011 Dec;1(4):219-225. doi: 10.1089/jcr.2011.0029. PY - 2011 SN - 2156-5783 (Print) 2156-5368 SP - 219-225 ST - Evaluating Dependence Criteria for Caffeine T2 - J Caffeine Res TI - Evaluating Dependence Criteria for Caffeine VL - 1 ID - 4227 ER - TY - JOUR AB - BACKGROUND AND OBJECTIVES: The purpose of the present study was to evaluate the results of diagnostic laparoscopy in children with chronic recurrent abdominal pain. PATIENTS AND METHODS: Thirteen children with chronic recurrent abdominal pain were subjected to diagnostic laparoscopy. Ages varied from 10 to 17 years. There were six males and seven females. Abdominal pain was present from 3 weeks to 12 months (mean, 2 months). Extensive laboratory and imaging studies did not contribute to the diagnosis. In all patients, the pain was disabling and severe enough to warrant repeated visits to the pediatrician, emergency room visits, or hospital admissions, as well as absence from school. RESULTS: All children recovered uneventfully. Laparoscopic findings that identified the cause of abdominal pain were obtained in 12 of 13 patients. Laparoscopic appendectomy was done in all patients. There were no operative complications. One child presented three months later with incomplete small bowel obstruction, which resolved with conservative management. There were no other postoperative complications. Follow-up varied from six months to three years. Abdominal pain resolved in ten patients. One patient presented eight months later with biliary dyskinesia. She improved following laparoscopic cholecystectomy and later on sphincterotomy, but her pain has not yet completely resolved. One patient presented six months later with abdominal pain secondary to intestinal adhesions. Her pain completely resolved after laparoscopic lysis of adhesions. A third patient who developed lower abdominal pain six months after laparoscopy improved with conservative management and antibiotics for pelvic inflammatory disease. CONCLUSIONS: Diagnostic laparoscopy is a valuable procedure in the management of children with chronic recurrent abdominal pain. In the present study, laparoscopic examination revealed the cause of abdominal pain in most patients, and this pain resolved in most cases. Based on our experience, we recommend diagnostic laparoscopy early in the course of debilitating chronic recurrent abdominal pain in children. Appendectomy should be done when no other significant cause of abdominal pain has been identified, even if the appendix looks normal. AD - Department of Surgery, New York Medical College, Westchester County Medical Center, Valhalla 10594, USA. AN - 10527334 AU - Stringel, G. AU - Berezin, S. H. AU - Bostwick, H. E. AU - Halata, M. S. C2 - PMC3113158 DA - Jul-Sep DP - NLM ET - 1999/10/20 IS - 3 KW - Abdominal Pain/*diagnosis/*surgery Adolescent Appendectomy/*methods Appendicitis/diagnosis/surgery Child Chronic Disease Female Follow-Up Studies Humans Laparoscopy/*methods Male Treatment Outcome LA - eng N1 - 1938-3797 Stringel, G Berezin, S H Bostwick, H E Halata, M S Clinical Trial Journal Article JSLS. 1999 Jul-Sep;3(3):215-9. PY - 1999 SN - 1086-8089 (Print) 1086-8089 SP - 215-9 ST - Laparoscopy in the management of children with chronic recurrent abdominal pain T2 - Jsls TI - Laparoscopy in the management of children with chronic recurrent abdominal pain VL - 3 ID - 3488 ER - TY - JOUR AB - Editors' Summary Background Worldwide, more than a billion people are infected with soil-transmitted helminths (STHs), parasitic worms that live in the human intestine (gut). These intestinal worms, including roundworm, hookworm, and whipworm, mainly occur in tropical and subtropical regions and are most common in developing countries, where personal hygiene is poor, there is insufficient access to clean water, and sanitation (disposal of human feces and urine) is inadequate or absent. STHs colonize the human intestine and their eggs are shed in feces and enter the soil. Humans ingest the eggs, either by touching contaminated ground or eating unwashed fruit and vegetables grown in such soil. Hookworm may enter the body by burrowing through the skin, most commonly when bare-footed individuals walk on infected soil. Repeated infection with STHs leads to a heavy parasite infestation of the gut, causing chronic diarrhea, intestinal bleeding, and abdominal pain. In addition the parasites compete with their human host for nutrients, leading to malnutrition, anemia, and, in heavily infected children, stunting of physical growth and slowing of mental development. Why Was This Study Done? ? While STH infections can be treated in the short-term with deworming medication, rapid re-infection is common, therefore a more comprehensive program of improved water, sanitation, and hygiene (WASH) is needed. WASH strategies include improvements in water access (e.g., water quality, water quantity, and distance to water), sanitation access (e.g., access to improved latrines, latrine maintenance, and fecal sludge management), and hygiene practices (e.g., handwashing before eating and/or after defecation, water treatment, soap use, wearing shoes, and water storage practices). WASH strategies have been shown to be effective for reducing rates of diarrhea and other neglected tropical diseases, such as trachoma; however, there is limited evidence linking specific WASH access or practices to STH infection rates. In this systematic review and meta-analysis, the researchers investigate whether WASH access or practices lower the risk of STH infections. A systematic review uses predefined criteria to identify all the research on a given topic; a meta-analysis is a statistical method that combines the results of several studies. What Did the Researchers Do and Find? ? The researchers identified 94 studies that included measurements of the relationship between WASH access and practices with one or more types of STHs. Meta-analyses of the data from 35 of these studies indicated that overall people with access to WASH strategies or practices were about half as likely to be infected with any STH. Specifically, a lower odds of infection with any STH was observed for those people who use treated water (odd ratio [OR] of 0.46), have access to sanitation (OR of 0.66), wear shoes (OR of 0.30), and use soap or have soap availability (OR of 0.53) compared to those without access to these practices or strategies. In addition, infection with roundworm was less than half as likely in those who practiced handwashing both before eating and after defecating than those who did not practice handwashing (OR of 0.38 and 0.45, respectively). What Do These Findings Mean? ? The studies included in this systematic review and meta-analysis have several shortcomings. For example, most were cross-sectional surveys-studies that examined the effect of WASH strategies on STH infections in a population at a single time point. Given this study design, people with access to WASH strategies may have shared other characteristics that were actually responsible for the observed reductions in the risk of STH infections. Consequently, the overall quality of the included studies was low and there was some evidence for publication bias (studies showing a positive association are more likely to be published than those that do not). Nevertheless, these findings confirm that WASH access and practices provide an effective control measure for STH. Controlling STHs in developing countries would have a huge positive impact on the physical and mental health of the population, especially children, therefore there should be more emphasis on expanding access to WASH as part of development guidelines and targets, in addition to short-term preventative chemotherapy currently used. Additional Information Please access these websites via the online version of this summary at http://dx.doi.org/10.1371/journal.pmed.1001620. The US Centers for Disease Control and Prevention also provides detailed information on roundworm, whipworm, and hookworm infections The World Health Organization provides information on soil-transmitted helminths, including a description of the current control strategy Children Without Worms (CWW) partners with Johnson & Johnson, GlaxoSmithKline, the World Health Organization, national ministries of health and education, non-governmental organizations, and others to promote treatment and prevention of soil-transmitted helminthiasis. CWW advocates a four-pronged, comprehensive control strategy-Water, Sanitation, Hygiene Education, and Deworming (WASHED) to break the cycle of reinfection The Global Network for Neglected Tropical Diseases, an advocacy initiative dedicated to raising the awareness, political will, and funding necessary to control and eliminate the most common neglected tropical diseases, provides information on infections with roundworm (ascariasis), whipworm (trichuriasis), and hookworm WASH for the Neglected Tropical Diseases is a repository of information on WASH and the neglected tropical diseases (NTDs) such as soil-transmitted helminthiasis, and features a resource titled "WASH and the NTDs: A Manual for WASH Implementers." Two international programs promoting water sanitation are the World Health Organization Water Sanitation and Health program and the World Health Organization/United Nations Childrens Fund Joint Monitoring Programme for Water Supply and Sanitation Background Preventive chemotherapy represents a powerful but short-term control strategy for soil-transmitted helminthiasis. Since humans are often re-infected rapidly, long-term solutions require improvements in water, sanitation, and hygiene (WASH). The purpose of this study was to quantitatively summarize the relationship between WASH access or practices and soil-transmitted helminth (STH) infection. Methods and Findings We conducted a systematic review and meta-analysis to examine the associations of improved WASH on infection with STH (Ascaris lumbricoides, Trichuris trichiura, hookworm [Ancylostoma duodenale and Necator americanus], and Strongyloides stercoralis). PubMed, Embase, Web of Science, and LILACS were searched from inception to October 28, 2013 with no language restrictions. Studies were eligible for inclusion if they provided an estimate for the effect of WASH access or practices on STH infection. We assessed the quality of published studies with the Grades of Recommendation, Assessment, Development and Evaluation (GRADE) approach. A total of 94 studies met our eligibility criteria; five were randomized controlled trials, whilst most others were cross-sectional studies. We used random-effects meta-analyses and analyzed only adjusted estimates to help account for heterogeneity and potential confounding respectively. Use of treated water was associated with lower odds of STH infection (odds ratio [OR] 0.46, 95% CI 0.36-0.60). Piped water access was associated with lower odds of A. lumbricoides (OR 0.40, 95% CI 0.39-0.41) and T. trichiura infection (OR 0.57, 95% CI 0.45-0.72), but not any STH infection (OR 0.93, 95% CI 0.28-3.11). Access to sanitation was associated with decreased likelihood of infection with any STH (OR 0.66, 95% CI 0.57-0.76), T. trichiura (OR 0.61, 95% CI 0.50-0.74), and A. lumbricoides (OR 0.62, 95% CI 0.44-0.88), but not with hookworm infection (OR 0.80, 95% CI 0.61-1.06). Wearing shoes was associated with reduced odds of hookworm infection (OR 0.29, 95% CI 0.18-0.47) and infection with any STH (OR 0.30, 95% CI 0.11-0.83). Handwashing, both before eating (OR 0.38, 95% CI 0.26-0.55) and after defecating (OR 0.45, 95% CI 0.35-0.58), was associated with lower odds of A. lumbricoides infection. Soap use or availability was significantly associated with lower infection with any STH (OR 0.53, 95% CI 0.29-0.98), as was handwashing after defecation (OR 0.47, 95% CI 0.24-0.90). Observational evidence constituted the majority of included literature, which limits any attempt to make causal inferences. Due to underlying heterogeneity across observational studies, the meta-analysis results reflect an average of many potentially distinct effects, not an average of one specific exposure-outcome relationship. Conclusions WASH access and practices are generally associated with reduced odds of STH infection. Pooled estimates from all meta-analyses, except for two, indicated at least a 33% reduction in odds of infection associated with individual WASH practices or access. Although most WASH interventions for STH have focused on sanitation, access to water and hygiene also appear to significantly reduce odds of infection. Overall quality of evidence was low due to the preponderance of observational studies, though recent randomized controlled trials have further underscored the benefit of handwashing interventions. Limited use of the Joint Monitoring Program's standardized water and sanitation definitions in the literature restricted efforts to generalize across studies. While further research is warranted to determine the magnitude of benefit from WASH interventions for STH control, these results call for multi-sectoral, integrated intervention packages that are tailored to social-ecological contexts. Please see later in the article for the Editors' Summary AN - WOS:000333408000007 AU - Strunz, E. C. AU - Addiss, D. G. AU - Stocks, M. E. AU - Ogden, S. AU - Utzinger, J. AU - Freeman, M. C. DA - Mar DO - 10.1371/journal.pmed.1001620 IS - 3 N1 - Strunz, Eric C. Addiss, David G. Stocks, Meredith E. Ogden, Stephanie Utzinger, Juerg Freeman, Matthew C. Freeman, Matthew/ABE-6245-2020 Freeman, Matthew/0000-0002-1517-2572 1549-1676 PY - 2014 SN - 1549-1277 ST - Water, Sanitation, Hygiene, and Soil-Transmitted Helminth Infection: A Systematic Review and Meta-Analysis T2 - Plos Medicine TI - Water, Sanitation, Hygiene, and Soil-Transmitted Helminth Infection: A Systematic Review and Meta-Analysis UR - ://WOS:000333408000007 VL - 11 ID - 2319 ER - TY - JOUR AB - CONTEXT AND OBJECTIVE: Primary headaches may be responsible for absenteeism and a fall in the yield and productivity of work. The aim of this study was to establish the presence and frequency of primary headache among employees of a rubber shoe sole company, and its link to absenteeism. DESIGN AND SETTING: Cross-sectional study carried out with help from the staff of the medical and social department of a rubber factory located in the municipality of Franca, São Paulo. METHOD: A questionnaire on headache characteristics was distributed to all employees. The returned and completed questionnaires were divided into two groups: with and without reports of headache. The headaches were classified into four main groups: migraine, tension-type headache (TTH), cluster headache and others. In terms of the reported frequency, headaches were also classified as chronic daily headache (CDH). RESULTS: The number of valid questionnaires was 392 (59%); 80.9% were from male and 19.1% from female employees. Headaches were reported by 120 subjects (30.6%), with 17.4% belonging to the migraine group and 8.9% to the TTH group. Migraine was more frequent (p < 0.001) among all participants and also among the women (p < 0.05). TTH was more frequent among the men (p < 0.05). CDH was identified in 14 individuals (3.6%). CONCLUSIONS: Headache was a common problem among the employees of this company and was a cause of absenteeism for 8.7% of the respondents to the questionnaire. AD - Department of Neurosciences, Universidade de São Paulo (FMRP-USP), Ribeirão Preto, Brazil. juliana.dentista@gmail.com AN - 21603782 AU - Stuginski-Barbosa, J. AU - Speciali, J. G. DA - Mar DO - 10.1590/s1516-31802011000200003 DP - NLM ET - 2011/05/24 IS - 2 KW - Absenteeism Adolescent Adult Age Distribution Brazil/epidemiology Cluster Headache/epidemiology Cross-Sectional Studies Female Headache Disorders, Primary/classification/*epidemiology Humans Male Middle Aged Migraine Disorders/epidemiology Occupational Diseases/*epidemiology Occupational Health Pain Measurement Prevalence Sex Distribution Shoes Statistics, Nonparametric Surveys and Questionnaires Tension-Type Headache/epidemiology Young Adult LA - eng N1 - 1806-9460 Stuginski-Barbosa, Juliana Speciali, José Geraldo Journal Article Brazil Sao Paulo Med J. 2011 Mar;129(2):66-72. doi: 10.1590/s1516-31802011000200003. PY - 2011 SN - 1516-3180 SP - 66-72 ST - Frequency of headache among the employees of a rubber company in the state of São Paulo, Brazil T2 - Sao Paulo Med J TI - Frequency of headache among the employees of a rubber company in the state of São Paulo, Brazil VL - 129 ID - 3233 ER - TY - JOUR AB - Background: Child abuse is a public health and human rights issue that is prevalent worldwide. All forms of abuse against children can have negative physical and mental health consequences. Under post-disaster situations, where there is a potential for increased stress and decreased social support among caregivers, the risk of child abuse may be higher. Objective: To explore the association between earthquake-related losses (family-related and property-related) and the experience of emotional, physical, and severe physical child abuse in the household for children aged 2-14 in Hail. Methods: A nationally representative sample of Haitian households from the 2012 Demographic and Health Survey (DHS) was used. Descriptive analyses were summarized using frequencies and measures of central tendency. Associations between earthquake-related loss and child abuse was assessed using log-binomial regression modelling. Results: Two years following the earthquake, and after considering potentially confounding variables, death of a household member was associated with a higher likelihood of a child being victim to emotional (RR = 1.11, 95 % CI: 1.05 -1.17) and severe physical abuse (RR = 1.50, 95 % CI: 1.15 -1.96). Conversely, injury of a household member was associated with a lower likelihood of a child experiencing emotional abuse (RR = 0.93, 95 % CI: 0.87 - 0.99). Conclusions: There were associations between earthquake-related losses and some forms of child abuse; the results were not consistent across all exposures and outcomes. The high prevalence of reported child abuse indicates a need for interventions to reduce child abuse in homes overall. There is also need for further research into the aetiology and influences specific to different types of abuse. AN - WOS:000543362000013 AU - Subedi, S. AU - Davison, C. AU - Bartels, S. C7 - 104509 DA - Aug DO - 10.1016/j.chiabu.2020.104509 N1 - Subedi, Sony Davison, Colleen Bartels, Susan 1873-7757 PY - 2020 SN - 0145-2134 ST - Analysis of the relationship between earthquake-related losses and the frequency of child-directed emotional, physical, and severe physical abuse in Haiti T2 - Child Abuse & Neglect TI - Analysis of the relationship between earthquake-related losses and the frequency of child-directed emotional, physical, and severe physical abuse in Haiti UR - ://WOS:000543362000013 VL - 106 ID - 1807 ER - TY - CHAP A2 - Sultan, C. AB - Primary dysmenorrhea, which affects from 43 to 91% of adolescent girls, is defined as painful uterine cramps that precede and accompany menses. Primary dysmenorrhea is related to an overproduction of uterine prostaglandins which induces myometrium hypercontractility and arterioral vasoconstriction, both involved in painful menstrual cramps. In addition, headache, nausea, asthenia, irritability and school absenteeism are frequently reported and need to be quantified through a clinical score. Despite its relevant impact on adolescent quality of life and availability of efficacious medication such as non-steroidal anti-inflammatory drugs, only 15% of affected adolescents consult a physician for this pain syndrome. Pediatricians and gynecologists should thus be more actively involved in the diagnosis and treatment of adolescent primary dysmenorrhea. Copyright (C) 2012 S. Karger AG, Basel AN - WOS:000310771800012 AU - Sultan, C. AU - Gaspari, L. AU - Paris, F. N1 - Sultan, Charles Gaspari, Laura Paris, Francoise Paris, Francoise/AAC-6553-2019 1421-7082 PY - 2012 SN - 978-3-8055-9336-6 SP - 171-180 ST - Adolescent Dysmenorrhea T2 - Pediatric and Adolescent Gynecology: Evidence-Based Clinical Practice, 2nd Edition T3 - Endocrine Development TI - Adolescent Dysmenorrhea UR - ://WOS:000310771800012 VL - 22 ID - 2453 ER - TY - JOUR AB - Background: Cancer has become increasingly prevalent in China over the past few decades. Among the factors that determine the quality of life of cancer patients, pain has commonly been recognized as a most critical one; it could also lead to the ineffective treatment of the cancer. Driven by the need for better pain management for cancer patients, our research team developed a mobile-based Intelligent Pain Management System (IPMS). Objective: Our objective was to design, develop, and test the IPMS to facilitate real-time pain recording and timely intervention among cancer patients with pain. The system's usability, feasibility, compliance, and satisfaction were also assessed. Methods: A sample of 46 patients with cancer pain symptoms were recruited at the Oncology Center of Xinhua Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Chongming Branch (hereinafter referred to as "the Oncology Center"). In a pretest, participants completed a pain management knowledge questionnaire and were evaluated using the baseline cancer pain assessment and Karnofsky Performance Status (KPS) evaluation. The participants were then randomly assigned into two groups (the trial group and the control group). After a 14-day trial period, another round of cancer pain assessment, KPS evaluation and pain management knowledge assessment were repeated. In the trial group, the data were fully automatically collected by the IPMS. In the control group, the data were collected using conventional methods, such as phone interviews or door-to-door visits by physicians. The participants were also asked to complete a satisfaction questionnaire on the use of the IPMS. Results: All participants successfully completed the trial. First, the feasibility of IPMS by observing the number of daily pain assessments recorded among patients was assessed. Second, the users' satisfaction, effectiveness of pain management, and changes in the quality of their lives were evaluated. All the participants gave high satisfaction score after they used IMPS. Both groups reported similar pain scores and KPS scores at the baseline. At the end of the trial, the mean pain score of the trial group was significantly lower than of the control group (P<. 001). The ending KPS score of the trial group was significantly higher than of the control group (P<. 001). The improvement of pain management knowledge score in the trial group was more pronounced than that in the control group (P<. 001). Conclusions: This study provided preliminary data to support the potentials of using IPMS in cancer pain communication between patients and doctors and to provide real-time supportive intervention on a convenient basis at a low cost. Overall, the IPMS can serve as a reliable and effective approach to control cancer pain and improve quality of life for patients with cancer pain. AN - WOS:000431849300014 AU - Sun, Y. H. AU - Jiang, F. AU - Gu, J. J. AU - Wang, Y. K. AU - Hua, H. W. AU - Li, J. AU - Cheng, Z. J. AU - Liao, Z. J. AU - Huang, Q. AU - Hu, W. W. AU - Ding, G. C7 - e108 DA - Jul DO - 10.2196/mhealth.7178 IS - 7 N1 - Sun, Yunheng Jiang, Feng Gu, Juan J. Wang, Y. Ken Hua, Hongwei Li, Jing Cheng, Zhijun Liao, Zhijun Huang, Qian Hu, Weiwei Ding, Gang Sun, Yunheng/0000-0003-2931-2641; Wang, Y. Ken/0000-0003-2829-3776 PY - 2017 SN - 2291-5222 ST - Development and Testing of an Intelligent Pain Management System (IPMS) on Mobile Phones Through a Randomized Trial Among Chinese Cancer Patients: A New Approach in Cancer Pain Management T2 - Jmir Mhealth and Uhealth TI - Development and Testing of an Intelligent Pain Management System (IPMS) on Mobile Phones Through a Randomized Trial Among Chinese Cancer Patients: A New Approach in Cancer Pain Management UR - ://WOS:000431849300014 VL - 5 ID - 2086 ER - TY - JOUR AB - Background: Studies on school students are indicating that somatic complaints and pain have increased during the past decades. Throughout this period there has been a change in methodology from proxy reports by parents to having the students themselves act as the respondents, possible explaining some of the increase in prevalence. The aim of this study was to compare the agreement of answers from students with answers given by their parents regarding the students' medical background and subjective rating of perceived health with specific focus on frequency of headache, musculoskeletal pain and tiredness. Methods: The participating students came from eleven different schools in Sweden. The schools were a sub sample of randomly selected schools originally participating in a larger multidisciplinary base study. Those 8th grade students present at school on the test date became the subjects of the investigation. A total of 232 students answered, assisted by the test leader, a specially designed self-complete questionnaire at school. Their parents were, at the same time, contacted and 200 answered a similar mailed-out questionnaire. One hundred and eighty-six ( 186) corresponding student-same parent questionnaires were registered for which comparisons of answers could be made and analysis conducted. Results: When a child is in good health, in absence of diseases, pain and injuries, his or her assessment matches up with their parent. Children and parents also showed agreement in cases of severe injuries and frequent ( daily) complaints of knee pain. Less frequent headaches, back-and musculoskeletal pain and other complaints of minor injuries and less wellbeing, such as students' tiredness, were all under-reported and under-rated by their parents. Conclusion: When assessing the perceived health and wellbeing of students, their own expressions should be the basis for the data collection and analysis rather than relying entirely on parental reports. AN - WOS:000242162700001 AU - Sundblad, G. M. B. AU - Saartok, T. AU - Engstrom, L. M. T. C7 - 276 DA - Nov DO - 10.1186/1471-2458-6-276 N1 - Sundblad, Gunilla M. Brun Saartok, Tonu Engstrom, Lars-Magnus T. 1471-2458 PY - 2006 ST - Child-parent agreement on reports of disease, injury and pain T2 - Bmc Public Health TI - Child-parent agreement on reports of disease, injury and pain UR - ://WOS:000242162700001 VL - 6 ID - 2713 ER - TY - JOUR AB - AIM: The aim of this study was to validate the Pain Catastrophizing Scale (PCS) in the Turkish population and to investigate its correlation with the demographic and clinical characteristics of patients. MATERIALS AND METHODS: Volunteer patients, who were scheduled for elective surgery and who applied to the Outpatient Clinic of Anesthesiology for preoperative evaluation, were asked to complete a PCS form. The patient's age, sex, educational level, marital status, presence of chronic pain, and American Society of Anesthesiologists score were recorded, and PCS scores and demographic variables were compared statistically. RESULTS: Of the 257 patients enrolled in the study, 136 were male, 121 female, and the median age was 40. The 3 subscales in the Turkish version of the PCS consisted of rumination, magnification, and helplessness. Internal consistency of PCS was found to be congruent with Cronbach's alpha = 0.90. Significantly higher PCS scores were found in women with chronic pain. In addition, patients who graduated from primary school had statistically higher scores compared to those who graduated from high school. CONCLUSION: In accordance with the original scale, demographic specifications of the Turkish version of the PCS were found congruent. PCS scores in our population were found compatible with the literature review. AD - Department of Anesthesiology, Gaziosmanpaşa University, Tokat, Turkey. mustafasuren@yahoo.com AN - 25558568 AU - Süren, M. AU - Okan, I. AU - Gökbakan, A. M. AU - Kaya, Z. AU - Erkorkmaz, U. AU - Arici, S. AU - Karaman, S. AU - Kahveci, M. DO - 10.3906/sag-1206-67 DP - NLM ET - 2015/01/07 IS - 1 KW - Adult Catastrophization/*diagnosis Educational Status Female Humans Male Middle Aged Pain Perception LA - eng N1 - Süren, Mustafa Okan, Ismail Gökbakan, Aziz Mehmet Kaya, Ziya Erkorkmaz, Unal Arici, Semih Karaman, Serkan Kahveci, Mürsel Journal Article Validation Study Turkey Turk J Med Sci. 2014;44(1):104-8. doi: 10.3906/sag-1206-67. PY - 2014 SN - 1300-0144 (Print) 1300-0144 SP - 104-8 ST - Factors associated with the pain catastrophizing scale and validation in a sample of the Turkish population T2 - Turk J Med Sci TI - Factors associated with the pain catastrophizing scale and validation in a sample of the Turkish population VL - 44 ID - 4193 ER - TY - JOUR AB - Background Recurrent abdominal pain is common among adolescents. School absenteeism and lower quality of life are associated with severity of symptoms. Lansoprazole has been used to treat recurrent abdominal pain. Objective To investigate the effectiveness of lansoprazole as a treatment for recurrent abdominal pain in adolescents. Methods We conducted a randomized, double-blind, controlled trial from August 2009 to October 2009. Adolescents suffering recurrent abdominal pain were eligible for the study. Simple randomization was done to divide subjects into two groups. Groups received 30 mg of lansoprazole or placebo, once a day for 14 days. Before treatment, we performed laboratory and physical examinations. Pain frequency was measured in number of abdominal pain episodes per month. Duration was measured in minutes and pain intensity was measured by a pain rating scale. Drug efficacy was measured before, during and after intervention. Data was analyzed using Mann-Whitney U-test and t-test. Results One hundred sixteen recurrent abdominal pain patients were randomized into two groups of 58 patients. There were no statistically significant differences in pain frequency before and after treatment for either the lansoprazole group or the placebo group (P=0.083, 95% CI, -0.033 to 0.021 and P=0.096, 95% CI -0.376 to 0.031, respectively). In addition, there were no significant differences in frequency, duration, and degree of abdominal pain at baseline and after 1, 2 and 3 months of treatment between the two groups. Conclusion Lansoprazole was not more effective than the placebo for treatment of recurrent abdominal pain among adolescents. AN - WOS:000217015300010 AU - Surya, A. S. AU - Nafianti, S. AU - Deliana, M. AU - Supriatmo AU - Sinuhaji, A. B. DA - Jul DO - 10.14238/pi51.4.2011.234-40 IS - 4 N1 - Surya, Ade Saifan Nafianti, Selvi Deliana, Melda Supriatmo Sinuhaji, Atan Baas 2338-476x PY - 2011 SN - 0030-9311 SP - 234-240 ST - Lansoprazole for recurrent abdominal pain in adolescents T2 - Paediatrica Indonesiana TI - Lansoprazole for recurrent abdominal pain in adolescents UR - ://WOS:000217015300010 VL - 51 ID - 2487 ER - TY - JOUR AB - OBJECTIVES: The purpose of this study was to evaluate a multidisciplinary, interventional, ergonomic education program designed to reduce the risk of musculoskeletal problems by reducing schoolbag weight and correcting poor sitting posture. METHODS: Data were collected twice before and twice following intervention using the Standardized Nordic Body Map Questionnaire, a rapid upper limb assessment for posture evaluation, and schoolbag weight measurement in children aged 8 and 11 years attending two schools within the central region of Malaysia. RESULTS: Students who received the ergonomic intervention reported significant improvements in their sitting posture in a classroom environment and reduction of schoolbag weight as compared with the controls. CONCLUSION: A single-session, early intervention, group ergonomics education program for children aged 8 and 11 years is appropriate and effective, and should be considered as a strategy to reduce musculoskeletal pain among schoolchildren in this age group. AU - Syazwan, Ai AU - Azhar, Mn Mohamad AU - Anita, Ar AU - Azizan, Hs AU - Shaharuddin, Ms AU - Hanafiah, J. Muhamad AU - Muhaimin, Aa AU - Nizar, Am AU - Rafee, B. Mohd AU - Ibthisham, A. Mohd AU - Kasani, Adam DA - 2011 DO - 10.2147/JPR.S22281 DP - PubMed J2 - J Pain Res KW - assessment awareness education ergonomic intervention musculoskeletal pain school children LA - eng PY - 2011 SN - 1178-7090 SP - 287-296 ST - Poor sitting posture and a heavy schoolbag as contributors to musculoskeletal pain in children T2 - Journal of Pain Research TI - Poor sitting posture and a heavy schoolbag as contributors to musculoskeletal pain in children: an ergonomic school education intervention program UR - http://www.ncbi.nlm.nih.gov/pubmed/22003301 VL - 4 ID - 97 ER - TY - JOUR AB - Consumption of sugary drinks is associated with the development of obesity and cardiometabolic diseases among children and adolescents. In addition to high added sugar content, many sugary drinks also contain caffeine. However, whether the combination of sugar and caffeine uniquely influences children's sugary drink intake is presently unknown. This study aimed to evaluate contextual factors surrounding children's sugary drink consumption and investigate reasons for sugary drink intake among children and adolescents, with a specific focus on caffeinated sodas and sweet tea. We also evaluated how sugary drink consumption makes children feel and how they anticipated that they would respond if sugary drinks were restricted. Focus group discussions (n = 9, 2-8 participants per group) were conducted with 37 predominantly AfricanAmerican children and adolescents, ages 8-14 years, who consumed >= 1 caffeine-containing sugary drink(s) daily, based on parental report. Focus groups were audio-recorded and transcribed verbatim. Transcripts were independently coded by two coders, after which emergent themes were identified. Reported reasons for sugary drink consumption encompassed five themes: 1) perceived need (e.g., satisfy cravings, quench thirst); 2) physical and cognitive benefits (e.g., provide energy, improve attention); 3) emotional and interpersonal benefits (e.g., relieve anger, facilitate socializing); 4) sensory properties (e.g., taste, carbonation); and, 5) external cues (e.g., family/peer modeling, availability). Negative consequences resulting from excess intake were also reported, including gastrointestinal symptoms, headaches, fatigue, hyperactivity, and chronic disease. Perceived physical, cognitive, emotional, and interpersonal benefits encourage sugary drink consumption and exacerbate well-described challenges of sugary drink reduction, including their palatability, accessibility, and affordability. Findings also suggest that incorporation of strategies to enhance physical, cognitive, and emotional health may hold promise in reducing sugary drink consumption among children and adolescents. AN - WOS:000573294600006 AU - Sylvetsky, A. C. AU - Visek, A. J. AU - Halberg, S. AU - Rhee, D. K. AU - Ongaro, Z. AU - Essel, K. D. AU - Dietz, W. H. AU - Sacheck, J. C7 - 104826 DA - Dec DO - 10.1016/j.appet.2020.104826 N1 - Sylvetsky, Allison C. Visek, Amanda J. Halberg, Sabrina Rhee, Dong Keun Ongaro, Zoe Essel, Kofi D. Dietz, William H. Sacheck, Jennifer Essel, Kofi/0000-0002-7320-9855; Rhee, Dong Keun/0000-0001-5027-1384 1095-8304 PY - 2020 SN - 0195-6663 ST - Beyond taste and easy access: Physical, cognitive, interpersonal, and emotional reasons for sugary drink consumption among children and adolescents T2 - Appetite TI - Beyond taste and easy access: Physical, cognitive, interpersonal, and emotional reasons for sugary drink consumption among children and adolescents UR - ://WOS:000573294600006 VL - 155 ID - 1781 ER - TY - JOUR AB - Musculoskeletal pain is one of the most common pains of adolescence, along with headache and abdominal pain, and arthralgia is the single most common reason for referral to the pediatric rheumatologist.(1) Not surprisingly,the pediatric rheumatologist is frequently called to distinguish organic from functional symptoms. During the past decade, the pediatric rheumatology community has been evaluating increasing numbers of adolescents and preadolescents who experience musculoskeletal symptoms presumable as a defense against emotional stress from achievement either in academic work or in sports. To complicate the challenge further, coexistence organic and psychologic disturbance is not rare. Clearly, organic illness does not protect a patient from emotional pain, and it may be most difficult to differentiate nonorganic pain in a patient with a known organic illness. Conversely, adolescents with organic illness may use their disease for secondary gain. Fear of misdiagnosis of physical illness as psychiatric and the notion that all of the patient's complaints should be explained by a unifying diagnosis cause diagnostic error in both psychogenic illness with physical manifestations and physical illness with psychogenic symptoms. AN - WOS:A1996UZ02200015 AU - Szer, I. S. DA - Jul DO - 10.1001/archpedi.1996.02170320086015 IS - 7 N1 - Szer, IS PY - 1996 SN - 1072-4710 SP - 740-747 ST - Musculoskeletal pain syndromes that affect adolescents T2 - Archives of Pediatrics & Adolescent Medicine TI - Musculoskeletal pain syndromes that affect adolescents UR - ://WOS:A1996UZ02200015 VL - 150 ID - 2924 ER - TY - JOUR AB - There is increasing evidence that non-specific low back pain (LBP) is common among children and adolescents, but there are few longitudinal studies on this subject. This is a longitudinal prospective study aimed at finding factors associated with the prediction of low back pain in schoolchildren aged 9-12 years, which is a younger age group than has previously been studied. This study was performed on school children in the city of Antwerp, Belgium. A total of 287 children filled out a questionnaire and were examined at the beginning of the study (T1) and 2 years later (T2). The questionnaire asked about back pain, general health, health perceptions, quality of life perceptions, sports, leisure, daily life, school life (weight of satchel.) and some issues related to parents (smoking, LBP). The questionnaire reliability was tested. Logistic regression was used to analyse the data. No predictors for LBP in children could be identified. Using logistic regression techniques, we analysed the children who reported no lifetime episode of LBP at both T1 and T2, the children who did report a lifetime episode at both T1 and T2 and also those who reported a history of LBP at T2 only (New LBP). At T2 there were 51 children (17.8%) reporting suffering at least one lifetime episode of LBP who had not reported such an episode at T1. Only one parameter showed a statistical difference: New LBP was observed significantly more frequently in children who do not walk to school ( P<0.0001). An interesting point of this study is that a number of children who had reported a history of LBP at T1 did not do so at T2. It may be that LBP in children is so benign and its natural history so favourable that the memory of the episode fades away. It is extremely interesting to note that among the few significant variables, those related to general well-being and self-perception of health, are prominent. It appears, therefore, that psychological factors play a role in the experience of LBP in a similar way to what has been reported in adults. Poor self-perception of health (health belief) could be a factor behind the reporting of LBP. Some variables linked to consequences of LBP (absence from school or from gym and visit to a doctor) play a significant role in reporting LBP, which suggests that those "health care" factors may reinforce a feeling of disease severity. AU - Szpalski, M. AU - Gunzburg, R. AU - Balagué, F. AU - Nordin, M. AU - Mélot, C. DA - 2002/10// DO - 10.1007/s00586-002-0385-y DP - PubMed IS - 5 J2 - Eur Spine J KW - Causality Child Female Health Status Humans Longitudinal Studies Low Back Pain Male Medical History Taking Physical Fitness Predictive Value of Tests Prospective Studies Quality of Life Reproducibility of Results Risk Factors Surveys and Questionnaires Weight-Bearing LA - eng PY - 2002 SN - 0940-6719 SP - 459-464 ST - A 2-year prospective longitudinal study on low back pain in primary school children T2 - European Spine Journal: Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society TI - A 2-year prospective longitudinal study on low back pain in primary school children UR - http://www.ncbi.nlm.nih.gov/pubmed/12384754 VL - 11 ID - 126 ER - TY - JOUR AB - PURPOSE OF REVIEW: This article reviews the approach to a child or adolescent with headache, the criteria for common diagnoses, and the evidence base for treatments. RECENT FINDINGS: The guidelines for acute and preventive treatment of migraine were updated in 2019. These guidelines summarize the available evidence and outline the questions that should be addressed in future research. The US Food and Drug Administration (FDA) approval of several new classes of drugs and devices to treat adult migraine in the past few years has resulted in ongoing or planned pediatric trials. SUMMARY: Headache is a common symptom in children, and it is important to take a detailed history and perform a thorough physical examination to make the diagnosis. Nearly 1 in 10 children experience recurrent headaches due to migraine, which cause significant impairment in school performance and quality of life. The acute and preventive treatments that are currently available will help at least two-thirds of children with migraine, and several trials of new therapies offer hope for the future. AN - 34048400 AU - Szperka, C. DA - Jun 1 DO - 10.1212/con.0000000000000993 DP - NLM ET - 2021/05/29 IS - 3 LA - eng N1 - 1538-6899 Szperka, Christina Journal Article United States Continuum (Minneap Minn). 2021 Jun 1;27(3):703-731. doi: 10.1212/CON.0000000000000993. PY - 2021 SN - 1080-2371 SP - 703-731 ST - Headache in Children and Adolescents T2 - Continuum (Minneap Minn) TI - Headache in Children and Adolescents VL - 27 ID - 4186 ER - TY - JOUR AB - HYPOTHESIS: Even with improved diagnostic modalities, the optimum management strategy for iliopsoas abscess (IPA) is not uniform, and a better understanding of treatment options is needed. DESIGN: Retrospective case series. SETTING: Academic center. PATIENTS: Sixty-one consecutive patients diagnosed as having IPA at the Mount Sinai Medical Center, New York, New York, from August 1, 2000, to December 30, 2007. MAIN OUTCOME MEASURES: Development and cause of IPA, the need for additional interventions, morbidity, and mortality. RESULTS: The mean age of the patients was 53 years. Most patients were initially seen with pain (95% [58 of 61]), gastrointestinal tract complaints (43% [26 of 61]), and lower extremity pain (30% [18 of 61]). Primary and secondary abscesses occurred in 11% (7 of 61) and 89% (54 of 61), respectively. The most frequent underlying cause of secondary abscesses was inflammatory bowel disease. Broad-spectrum antibiotics were prescribed in all patients. Computed tomography was the most common diagnostic modality used. Abscesses were larger than 6 cm in 39% of patients (24 of 61), bilateral in 13% (8 of 61), and multiple in 25% (15 of 61). Nine patients were treated using antibiotics alone, with a success rate of 78% (7 of 9). Forty-eight patients initially underwent percutaneous drainage, which was successful in 40% (19 of 48). Among those with unresolved IPAs, 71% of patients ultimately required surgery, and the IPAs were typically associated with underlying gastrointestinal tract causes. Seven percent (4 of 61) of patients directly underwent exploratory surgery and drainage, and all of these interventions were successful. The overall mortality was 5% (3 of 61). CONCLUSIONS: Iliopsoas abscess remains a therapeutic challenge. Gastrointestinal tract disease is the most common cause, with computed tomography as the diagnostic modality of choice. Percutaneous drainage remains the initial treatment modality but is rarely the sole therapy required. Patients with inflammatory bowel disease are likely to require ultimate operative management. AD - Division of General Surgery, Department of Surgery, Mount Sinai Medical Center, 5 E 98th St, New York, NY 10029, USA. AN - 19841363 AU - Tabrizian, P. AU - Nguyen, S. Q. AU - Greenstein, A. AU - Rajhbeharrysingh, U. AU - Divino, C. M. DA - Oct DO - 10.1001/archsurg.2009.144 DP - NLM ET - 2009/10/21 IS - 10 KW - Adolescent Adult Aged Aged, 80 and over Anti-Bacterial Agents/therapeutic use Cohort Studies Combined Modality Therapy Drainage Escherichia coli Infections/*diagnosis/etiology/*therapy Female Humans Male Middle Aged Psoas Abscess/*diagnosis/etiology/*therapy Retrospective Studies Staphylococcal Infections/*diagnosis/etiology/*therapy Treatment Outcome Young Adult LA - eng N1 - 1538-3644 Tabrizian, Parissa Nguyen, Scott Q Greenstein, Alexander Rajhbeharrysingh, Uma Divino, Celia M Journal Article United States Arch Surg. 2009 Oct;144(10):946-9. doi: 10.1001/archsurg.2009.144. PY - 2009 SN - 0004-0010 SP - 946-9 ST - Management and treatment of iliopsoas abscess T2 - Arch Surg TI - Management and treatment of iliopsoas abscess VL - 144 ID - 4095 ER - TY - JOUR AB - BackgroundNegative experiences with school-based immunizations can contribute to vaccine hesitancy in youth and adulthood. We developed an evidence-based, multifaceted and customizable intervention to improve the immunization experience at school called the CARD (TM) (C-Comfort, A-Ask, R-Relax, D-Distract) system. We evaluated the feasibility of CARD (TM) implementation for school-based immunizations in Calgary, Canada.MethodsIn a mixed methods study, two Community Health Centres providing immunization services, including 5 schools each with grade 9 students (aged approximately 14years), were randomized to CARD (TM) or control (usual care). In the CARD (TM) group, public health staff and students were educated about coping strategies prior to immunization clinics. Clinics were organized to reduce fear and to support student's choices for coping strategies. Public health staff in the CARD (TM) group participated in a focus group discussion afterwards. We sought a recruitment rate of 80% for eligible schools, an external stakeholder focus group (e.g., school staff) with 6 or more individuals, 85% of individual injection-related data acquisition (student and immunizer surveys), and 80% absolute agreement between raters for a subset of data that were double-coded. Across focus groups, we examined perceptions of acceptability, appropriateness, feasibility and fidelity of CARD (TM) .ResultsNine (90%) of eligible schools participated. Of 219 students immunized, injection-related student and immunizer data forms were acquired for 195 (89.0%) and 196 (89.5%), respectively. Reliability of data collection was high. Fifteen public health and 5 school staff participated in separate focus groups. Overall, attitudes towards CARD (TM) were positive and compliance with individual components of CARD (TM) was high. Public health staff expressed skepticism regarding the value of student participation in the CARD (TM) system. Suggestions were made regarding processes to refine implementation.ConclusionWhile most outcome criteria were satisfied and overall perceptions of implementation outcomes were positive, some important challenges and opportunities were identified. Feedback is being used to inform a large cluster trial that will evaluate the impact of CARD (TM) during school-based immunizations.Trial registrationThe trial is registered at ClinicalTrials.gov (NCT03948633); Submitted April 24, 2019. AN - WOS:000616571000004 AU - Taddio, A. AU - Coldham, J. AU - Logeman, C. AU - McMurtry, C. M. AU - Little, C. AU - Samborn, T. AU - Bucci, L. M. AU - MacDonald, N. E. AU - Shah, V. AU - Dribnenki, C. AU - Snider, J. AU - Stephens, D. C7 - 260 DA - Feb DO - 10.1186/s12889-021-10247-4 IS - 1 N1 - Taddio, Anna Coldham, Joanne Logeman, Charlotte McMurtry, C. Meghan Little, Cheri Samborn, Tracy Bucci, Lucie M. MacDonald, Noni E. Shah, Vibhuti Dribnenki, Cindy Snider, Joanne Stephens, Derek 1471-2458 PY - 2021 ST - Feasibility of implementation of CARD (TM) for school-based immunizations in Calgary, Alberta: a cluster trial T2 - Bmc Public Health TI - Feasibility of implementation of CARD (TM) for school-based immunizations in Calgary, Alberta: a cluster trial UR - ://WOS:000616571000004 VL - 21 ID - 1758 ER - TY - JOUR AB - Objective School-based vaccination programs can be a source of distress for many students due to the pain from the needle injection and related fears. We created a multifaceted Knowledge Translation (KT) intervention to address vaccination and pain, fear, and fainting called The CARD System. The objectives were to document acceptability of key tools included in the multifaceted KT intervention and their effectiveness in improving knowledge and attitudes about vaccination pain and fear. Methods Quantitative and qualitative methods were used. Students, school staff, public health nurses, and parents participated in separate focus groups whereby they independently completed a knowledge and attitudes survey and provided structured and qualitative feedback on key KT tools of the multifaceted KT intervention. They then repeated the knowledge and attitudes survey. Results Altogether, 22 students (grade 6 and 7), 16 school staff (principals, grade 7 and 8 teachers, resource teachers, secretaries), 10 nurses (injecting, charge, and school nurses), and 3 parents participated. Knowledge test scores increased post-KT tool review: 8.5 (2.1) versus 7.3 (1.9); P<0.001. Attitudes were more positive about the individual nature of pain and fear experience during vaccination. Student fear scores were lower post-tool review: 5.1 (2.9) versus 4.6 (3.0); P<0.001. The majority of the participants reported they understood all the information, the amount was just right and that the information was useful. Discussion The KT tools were demonstrated to be acceptable and to improve knowledge. Future research is warranted to determine their impact on student experience during school vaccinations. AN - WOS:000464947400004 AU - Taddio, A. AU - Freedman, T. AU - Wong, H. AU - McMurtry, C. M. AU - MacDonald, N. AU - Ilersich, A. N. T. AU - Ilersich, A. L. T. AU - McDowall, T. AU - Wilson, E. AU - Robson, K. AU - Filipovic, S. AU - Schmidt, C. AU - DeVlaming-Kot, C. AU - Alderman, L. AU - Alfieri-Maiolo, A. AU - Bucci, L. M. AU - Halpert, C. AU - Cortes, J. AU - Badali, M. AU - Hirji, M. M. AU - Pain Pain Go Away, Team DA - Apr DO - 10.1093/pch/pxz018 N1 - Taddio, Anna Freedman, Tamlyn Wong, Horace McMurtry, C. Meghan MacDonald, Noni Ilersich, Anthony N. T. Ilersich, Angelo L. T. McDowall, Tori Wilson, Evelyn Robson, Kate Filipovic, Srdjana Schmidt, Cathryn deVlaming-Kot, Christene Alderman, Leslie Alfieri-Maiolo, Angela Bucci, Lucie M. Halpert, Christine Cortes, Jocelyn Badali, Melanie Hirji, M. Mustafa 1918-1485 1 PY - 2019 SN - 1205-7088 SP - S29-S34 ST - Stakeholder feedback on The CARD System to improve the vaccination experience at school T2 - Paediatrics & Child Health TI - Stakeholder feedback on The CARD System to improve the vaccination experience at school UR - ://WOS:000464947400004 VL - 24 ID - 1936 ER - TY - JOUR AB - Background Students experience fear, pain, and fainting during vaccinations at school. While evidence-based interventions exist, no Knowledge Translation (KT) interventions have been developed to mitigate these symptoms. A multidisciplinary teamthe Pain Pain Go Away Teamwas assembled to address this knowledge-to-care gap. This manuscript provides an overview of the methodology, knowledge products, and impact of an evidence-based KT program developed and implemented to improve the vaccination experience at school. Methods We adapted knowledge and assessed the barriers to knowledge use via focus group interviews with key stakeholder groups involved in school-based vaccinations: students, nurses, school staff, and parents. Next, we developed project-specific goals and data collection tools and collected baseline data. We then created a multifaceted KT intervention called The CARD System (C-Comfort, A-Ask, R-Relax, D-Distract) to provide a framework for planning and delivering vaccinations using a student-centred approach. Selected KT tools from this framework were reviewed in additional focus groups held in all stakeholder groups. The multifaceted KT intervention was then finalized and implemented in stages in two projects including grade 7 students undergoing school vaccinations and impact on student outcomes (e.g., symptoms of fear, pain, dizziness) and process outcomes (e.g., utilization of interventions that reduce student symptoms, vaccination rate) were assessed. Results Participants reported that improving the vaccination experience is important. Based on participant feedback, an evidence-based multifaceted KT intervention called The CARD System was developed that addresses user needs and preferences. Selected KT tools of this intervention were demonstrated to be acceptable and to improve knowledge and attitudes about vaccination in the stakeholder groups. In two separate implementation projects, CARD helped grade 7 students prepare for vaccinations and positively impacted on their vaccination experiences. CARD improved vaccination experiences for other stakeholder groups as well. There was no evidence of an impact on school vaccination rates. Conclusion We developed and implemented a promising multifaceted KT intervention called The CARD System to address vaccination-associated pain, fear, and fainting. Future research is recommended to determine impact in students of different ages and in different geographical regions and clinical contexts. AN - WOS:000464947400002 AU - Taddio, A. AU - McMurtry, C. M. AU - Bucci, L. M. AU - MacDonald, N. AU - Ilersich, A. N. T. AU - Ilersich, A. L. T. AU - Alfieri-Maiolo, A. AU - deVlaming-Kot, C. AU - Alderman, L. AU - Freedman, T. AU - McDowall, T. AU - Wong, H. AU - Robson, K. AU - Halpert, C. AU - Wilson, E. AU - Cortes, J. AU - Hirji, M. M. AU - Schmidt, C. AU - Filipovic, S. AU - Badali, M. AU - Pain Pain Go Away, Team DA - Apr DO - 10.1093/pch/pxz025 N1 - Taddio, Anna McMurtry, C. Meghan Bucci, Lucie M. MacDonald, Noni Ilersich, Anthony N. T. Ilersich, Angelo L. T. Alfieri-Maiolo, Angela deVlaming-Kot, Christene Alderman, Leslie Freedman, Tamlyn McDowall, Tori Wong, Horace Robson, Kate Halpert, Christine Wilson, Evelyn Cortes, Jocelyn Hirji, M. Mustafa Schmidt, Cathryn Filipovic, Srdjana Badali, Melanie 1918-1485 1 PY - 2019 SN - 1205-7088 SP - S3-S18 ST - Overview of a Knowledge Translation (KT) Project to improve the vaccination experience at school: The CARD System T2 - Paediatrics & Child Health TI - Overview of a Knowledge Translation (KT) Project to improve the vaccination experience at school: The CARD System UR - ://WOS:000464947400002 VL - 24 ID - 1937 ER - TY - JOUR AB - PURPOSE: The aim of this study was the assessment of the quality of life of children and adolescents with tension headaches in comparison with healthy peers. MATERIAL AND METHODS: The study was conducted on 135 middle school and high school students in Poznań and on 86 children with tension headaches, that were treated in the out-patient clinic of The Chair and Clinic of Development Age Neurology of Karol Marcinkowski University of Medical Sciences in Poznań. The research tool for both groups was Pediatric Quality of Life Inventory, version 4.0 (PedsQL 4.0) questionnaire. RESULTS: In the analysed groups dominated 14- and 16-year-old children. Among children with tension headaches, the ailments usually appeared once or twice a week in 39 (45%) of them. With the use of the PedsQL 4.0 questionnaire the following fields of activity were analyzed: biological, emotional, social functioning and mood. CONCLUSIONS: The biggest discrepancies between the group of healthy children and those with headaches were noted in the field of emotional functioning and mood. Adolescents with tension headaches more frequently reported the feeling of fear and sleep disorders in comparison to healthy students. Children with headaches look at the future in a more pessimistic way and are less satisfied with their lives. AD - Faculty of Health Sciences, Karol Marcinkowski University of Medical Sciences, Poznań, Poland. pati.talarska@neostrada.pl AN - 16119645 AU - Talarska, D. DP - NLM ET - 2005/08/27 KW - Adolescent Child Female Humans Male Quality of Life Tension-Type Headache/*psychology LA - eng N1 - Talarska, D Journal Article Poland Rocz Akad Med Bialymst. 2005;50 Suppl 1:126-8. PY - 2005 SP - 126-8 ST - Quality of life in healthy children and in children with tension headaches--a comparative analysis T2 - Rocz Akad Med Bialymst TI - Quality of life in healthy children and in children with tension headaches--a comparative analysis VL - 50 Suppl 1 ID - 3406 ER - TY - JOUR AB - Multidisciplinary treatment programs for chronic pain typically emphasize the importance of decreasing maladaptive and encouraging adaptive coping responses. The Chronic Pain Coping Inventory (CPCI), developed to assess coping strategies targeted for change in multidisciplinary pain treatment, is a 64-item instrument that contains 8 subscales: Guarding, Resting, Asking for Assistance, Relaxation, Task Persistence, Exercising/Stretching, Coping Self-Statements, and Seeking Social Support. A previous validation study with 210 patients in a Canadian academic hospital setting supported an 8-factor structure for the CPCI. The current study was undertaken to validate the CPCI among 564 veterans with a more extended history of chronic pain. Patients completed the study questionnaires before multidisciplinary treatment.-A confirmatory factor analysis was used to examine the factor structure of the 64-item CPCI. A series of hierarchical multiple regression analyses were performed with depression, pain interference, general activity level, disability, and pain severity as the criterion variables and the 8 CPCI factors as the predictor variables, controlling for pain severity and demo-graphic variables. The confirmatory factor analysis results strongly supported an 8-factor model, and the regression analyses supported the predictive validity of the CPCI scales, as indicated by their association with measures of patient adjustment to chronic pain. Perspective: This article validated the 8-factor structure of the CPCI by using a confirmatory factor analysis and a series of linear regressions. The results support the applicability and utility of the CPCI in a heterogeneous population of veterans with severe chronic pain treated in a tertiary teaching hospital. The CPCI provides an important clinical and research tool for the assessment of behavioral pain coping strategies that might have an impact on patient outcomes. AN - WOS:000226462100006 AU - Tan, G. AU - Nguyen, Q. AU - Anderson, K. O. AU - Jensen, M. AU - Thornby, J. DA - Jan DO - 10.1016/j.jpain.2004.09.006 IS - 1 N1 - Tan, G Nguyen, Q Anderson, KO Jensen, M Thornby, J PY - 2005 SN - 1526-5900 SP - 29-40 ST - Further validation of the chronic pain coping inventory T2 - Journal of Pain TI - Further validation of the chronic pain coping inventory UR - ://WOS:000226462100006 VL - 6 ID - 2776 ER - TY - JOUR AB - Laparoscopic appendectomy has not been uniformly adopted by pediatric surgeons. Our children's hospital adopted laparoscopic appendectomy due to perceived benefits to patients and their families. We hypothesized that laparoscopic appendectomy in children resulted in less social morbidity than those undergoing open appendectomy. A questionnaire focused on a set of postoperative variables affecting the patient's and the family's return to normal activities. Families expressed their answers as a range of days. Five different ranges were assigned a numerical value for 10 different social morbidity variables. The numerical values were analyzed using Pearson X-2 test; statistical significance was defined as P < 0.05. The response rate was 55 per cent (134 of 244). Seventy-four had open and 47 laparoscopic appendectomy with a comparable incidence of acute and perforated appendicitis. Children undergoing laparoscopic appendectomy had shorter hospital stays and earlier resumption of feeding, return to school, return to pain-free walking and stair climbing, and resumption of normal activities including gym. Additionally, they had fewer wound problems, shorter duration of oral pain medication usage, and their parents returned to work quicker than the open group. All these were statistically significant. Laparoscopic appendectomy results in significantly reduced social morbidity for children and their families. AN - WOS:000224111000010 AU - Tantoco, J. G. AU - Levitt, M. A. AU - Hollands, C. M. AU - Brisseau, G. F. AU - Caty, M. G. AU - Glick, P. L. DA - Sep IS - 9 N1 - Tantoco, JG Levitt, MA Hollands, CM Brisseau, GF Caty, MG Glick, PL Annual Scientific Meeting of the Southeastern-Surgical-Congress Jan 31-feb 03, 2004 Atlanta, GA SE Surg Congress 1555-9823 PY - 2004 SN - 0003-1348 SP - 779-782 ST - Reduced social morbidity of laparoscopic appendectomy in children T2 - American Surgeon TI - Reduced social morbidity of laparoscopic appendectomy in children UR - ://WOS:000224111000010 VL - 70 ID - 2784 ER - TY - JOUR AB - INTRODUCTION: A growing body of literature has shown an association between somatic symptoms and insecure "attachment style." In a recent study, we found a relationship between migraine severity, ambivalent attachment style, and psychological symptoms in children/adolescents. There is evidence that caregivers' attachment styles and their way of management/expression of emotions can influence children's psychological profile and pain expression. To date, data dealing with headache are scarce. Our aim was to study the role of maternal alexithymia and attachment style on their children's migraine severity, attachment style, and psychological profile. MATERIALS AND METHODS: We enrolled 84 consecutive patients suffering from migraine without aura (female: 45, male: 39; mean age 11.8 ± 2.4 years). According to headache frequency, children/adolescents were divided into two groups: (1) high frequency (patients reporting from weekly to daily attacks), and (2) low frequency (patients having ≤3 episodes per month). We divided headache attacks intensity into two groups (mild and severe pain). SAFA "Anxiety," "Depression," and "Somatization" scales were used to explore children's psychological profile. To evaluate attachment style, the semi-projective test SAT for patients and ASQ Questionnaire for mothers were employed. Maternal alexithymia traits were assessed by TAS-20. RESULTS: We found a significant higher score in maternal alexithymia levels in children classified as "ambivalent," compared to those classified as "avoiding" (Total scale: p = 0.011). A positive correlation has been identified between mother's TAS-20 Total score and the children's SAFA-A Total score (p = 0.026). In particular, positive correlations were found between maternal alexithymia and children's "Separation anxiety" (p = 0.009) and "School anxiety" (p = 0.015) subscales. Maternal "Externally-oriented thinking" subscale correlated with children's school anxiety (p = 0.050). Moreover, we found a correlation between TAS-20 Total score and SAFA-D "Feeling of guilt" subscale (p = 0.014). Our data showed no relationship between TAS-20 and ASQ questionnaires and children's migraine intensity and frequency. CONCLUSION: Maternal alexithymia and attachment style have no impact on children's migraine severity. However, our results suggest that, although maternal alexithymic traits have no causative roles on children's migraine severity, they show a relationship with patients' attachment style and psychological symptoms, which in turn may impact on migraine severity. AD - Division of Neurology, Headache Center, Bambino Gesù Ospedale Pediatrico (IRCCS), Rome, Italy. Unit of Clinical Psychology, Ospedale Pediatrico Bambino Gesù (IRCCS), Rome, Italy. Center for Sensory-Motor Interaction, Aalborg University, Aalborg, Denmark. AN - 29403425 AU - Tarantino, S. AU - Papetti, L. AU - De Ranieri, C. AU - Boldrini, F. AU - Rocco, A. M. AU - D'Ambrosio, M. AU - Valeriano, V. AU - Battan, B. AU - Paniccia, M. F. AU - Vigevano, F. AU - Gentile, S. AU - Valeriani, M. C2 - PMC5786507 DO - 10.3389/fneur.2017.00751 DP - NLM ET - 2018/02/07 KW - alexithymia attachment style children migraine severity mothers psychological factors LA - eng N1 - 1664-2295 Tarantino, Samuela Papetti, Laura De Ranieri, Cristiana Boldrini, Francesca Rocco, Angela Maria D'Ambrosio, Monica Valeriano, Valeria Battan, Barbara Paniccia, Maria Francesca Vigevano, Federico Gentile, Simonetta Valeriani, Massimiliano Journal Article Front Neurol. 2018 Jan 22;8:751. doi: 10.3389/fneur.2017.00751. eCollection 2017. PY - 2017 SN - 1664-2295 (Print) 1664-2295 SP - 751 ST - Maternal Alexithymia and Attachment Style: Which Relationship with Their Children's Headache Features and Psychological Profile? T2 - Front Neurol TI - Maternal Alexithymia and Attachment Style: Which Relationship with Their Children's Headache Features and Psychological Profile? VL - 8 ID - 4108 ER - TY - JOUR AB - Introduction: A growing body of literature has shown an association between somatic symptoms and insecure "attachment style." In a recent study, we found a relationship between migraine severity, ambivalent attachment style, and psychological symptoms in children/adolescents. There is evidence that caregivers' attachment styles and their way of management/expression of emotions can influence children's psychological profile and pain expression. To date, data dealing with headache are scarce. Our aim was to study the role of maternal alexithymia and attachment style on their children's migraine severity, attachment style, and psychological profile. Materials and methods: We enrolled 84 consecutive patients suffering from migraine without aura (female: 45, male: 39; mean age 11.8 +/- 2.4 years). According to headache frequency, children/adolescents were divided into two groups: (1) high frequency (patients reporting from weekly to daily attacks), and (2) low frequency (patients having <= 3 episodes per month). We divided headache attacks intensity into two groups (mild and severe pain). SAFA "Anxiety," "Depression," and "Somatization" scales were used to explore children's psychological profile. To evaluate attachment style, the semi-projective test SAT for patients and ASQ Questionnaire for mothers were employed. Maternal alexithymia traits were assessed by TAS-20. Results: We found a significant higher score in maternal alexithymia levels in children classified as "ambivalent," compared to those classified as "avoiding" (Total scale: p = 0.011). A positive correlation has been identified between mother's TAS-20 Total score and the children's SAFA-A Total score (p = 0.026). In particular, positive correlations were found between maternal alexithymia and childrens "Separation anxiety" (p = 0.009) and "School anxiety" (p = 0.015) subscales. Maternal "Externally-oriented thinking" subscale correlated with childrens school anxiety (p = 0.050). Moreover, we found a correlation between TAS-20 Total score and SAFA-D "Feeling of guilt" subscale (p = 0.014). Our data showed no relationship between TAS-20 and ASQ questionnaires and childrens migraine intensity and frequency. Conclusion: Maternal alexithymia and attachment style have no impact on childrens migraine severity. However, our results suggest that, although maternal alexithymic traits have no causative roles on childrens migraine severity, they show a relationship with patients' attachment style and psychological symptoms, which in turn may impact on migraine severity. AN - WOS:000422993800001 AU - Tarantino, S. AU - Papetti, L. AU - De Ranieri, C. AU - Boldrini, F. AU - Rocco, A. M. AU - D'Ambrosio, M. AU - Valeriano, V. AU - Battan, B. AU - Paniccia, M. F. AU - Vigevano, F. AU - Gentile, S. AU - Valeriani, M. C7 - 751 DA - Jan DO - 10.3389/fneur.2017.00751 N1 - Tarantino, Samuela Papetti, Laura De Ranieri, Cristiana Boldrini, Francesca Rocco, Angela Maria D'Ambrosio, Monica Valeriano, Valeria Battan, Barbara Paniccia, Maria Francesca Vigevano, Federico Gentile, Simonetta Valeriani, Massimiliano Gentile, Simonetta/AAA-7410-2020; Papetti, Laura LP/B-1262-2013; Valeriani, Massimiliano/K-5736-2016; Vigevano, Federico/K-9466-2016 Gentile, Simonetta/0000-0003-2429-689X; Papetti, Laura LP/0000-0002-3336-9205; Valeriani, Massimiliano/0000-0001-6602-103X; Vigevano, Federico/0000-0001-7513-0051 PY - 2018 SN - 1664-2295 ST - Maternal Alexithymia and Attachment Style: Which relationship with Their Children's Headache Features and Psychological Profile? T2 - Frontiers in Neurology TI - Maternal Alexithymia and Attachment Style: Which relationship with Their Children's Headache Features and Psychological Profile? UR - ://WOS:000422993800001 VL - 8 ID - 2036 ER - TY - JOUR AB - We report the case of an 11-year-old girl who presented to our multidisciplinary pain center with the chief complaint of chronic bilateral foot pain because of a rare congenital keratin disorder. This patient had been diagnosed with pachyonychia congenita, an extremely rare genetic disorder primarily affecting the skin and nails. The child had bilateral foot pain for years because of the characteristic blisters and calluses on the soles of her feet. Chronic pain was negatively impacting her quality of life; she was severely limited in her activities of daily living secondary to pain. Furthermore, she reported absenteeism from school, lack of social activities, and frequent nighttime awakenings. We discuss the successful management of her chronic foot pain using a multimodal, multidisciplinary approach. AN - WOS:000376776500005 AU - Tariq, S. AU - Schmitz, M. L. AU - Kanjia, M. K. DA - May DO - 10.1213/xaa.0000000000000301 IS - 10 N1 - Tariq, Sarah Schmitz, Michael L. Kanjia, Megha Karkera PY - 2016 SN - 2325-7237 SP - 305-307 ST - Chronic Foot Pain due to Pachyonychia Congenita in a Pediatric Patient: A Successful Management Strategy T2 - A & a Case Reports TI - Chronic Foot Pain due to Pachyonychia Congenita in a Pediatric Patient: A Successful Management Strategy UR - ://WOS:000376776500005 VL - 6 ID - 2166 ER - TY - JOUR AB - STUDY DESIGN: Prospective study. OBJECTIVE: To assess the timing and predictors of return to short-term functional activity in patients with adolescent idiopathic scoliosis (AIS) after posterior spinal fusion (PSF). SUMMARY OF BACKGROUND DATA: Few studies have examined the timing and rate of return to short-term functional activity in patients with AIS after PSF. No study has yet evaluated the timing and factors that predict a delayed return to school/college--a topic relevant to patients who have had or anticipate having spinal fusion, and their treating surgeons. METHODS: Seventy-seven eligible subjects with AIS who underwent PSF and correction (January 2010 to April 2012) were followed up until return to the functional outcomes under analysis. Timing of return to school/college and physical activity, as per the patients' preoperative level or better, was assessed. Binary logistic regression analysis was used to determine predictors of delayed return to school/college full-time (>16 wk) and unrestricted physical activity (>32 wk) relative to sociodemographic, anthropometric, radiographical, clinical, and surgical factors. In the present study, a "delayed" return to all the functional outcomes recorded was defined as "greater than the 75th percentile" of the continuous distribution. RESULTS: Mean follow-up was 12.8 months (SD, 5.7). Mean age was 15.04 years (SD, 1.89). The median time to return to school/college full-time (n = 75) was 10 weeks; the majority returned by 16 weeks (77.3%). Preoperative curves greater than 70° (relative risk, 3.38; P = 0.008), postoperative weight loss greater than 5 kg (relative risk, 3.02; P = 0.012), and minor perioperative respiratory complication incidence (relative risk, 2.89; P = 0.024) independently predicted delayed return to school/college full-time. By 24 and 52 weeks, 51.4% and 88.5% of subjects, respectively, returned to unrestricted physical activity. At final follow-up, nonreturn to unrestricted physical activity was identified in only 3 subjects (4.3%) because of chronic back pain. CONCLUSION: The majority of patients with AIS can expect to return to school/college full-time by 16 weeks and unrestricted physical activity by 52 weeks after PSF. Preoperative curves greater than 70°, postoperative weight loss greater than 5 kg, and minor perioperative respiratory complication incidence independently predicted a delayed return to school/college full-time. These findings add to the current knowledge base regarding actual versus anticipated timing of return to short-term functional outcomes in this population. LEVEL OF EVIDENCE: 3. AD - *Department of Orthopaedic Surgery, Our Lady's Children's Hospital, Crumlin, Dublin 12, Ireland †National Children's Research Centre, Crumlin, Dublin 12, Ireland ‡Department of Anaesthetics, Our Lady's Children's Hospital, Crumlin, Dublin 12, Ireland; and §Blackrock Clinic, Blackrock, Dublin, Ireland. AN - 24875955 AU - Tarrant, R. C. AU - OʼLoughlin, P. F. AU - Lynch, S. AU - Queally, J. M. AU - Sheeran, P. AU - Moore, D. P. AU - Kiely, P. J. DA - Aug 15 DO - 10.1097/brs.0000000000000452 DP - NLM ET - 2014/05/31 IS - 18 KW - *Activities of Daily Living Adolescent Female Follow-Up Studies Humans Logistic Models Male Prognosis Prospective Studies Psychomotor Performance/*physiology Schools Scoliosis/*physiopathology/*surgery Spinal Fusion/*methods Time Factors Treatment Outcome Universities LA - eng N1 - 1528-1159 Tarrant, Roslyn C OʼLoughlin, Padhraig F Lynch, Sam Queally, Joseph M Sheeran, Padraig Moore, David P Kiely, Patrick J Journal Article Multicenter Study Research Support, Non-U.S. Gov't United States Spine (Phila Pa 1976). 2014 Aug 15;39(18):1471-8. doi: 10.1097/BRS.0000000000000452. PY - 2014 SN - 0362-2436 SP - 1471-8 ST - Timing and predictors of return to short-term functional activity in adolescent idiopathic scoliosis after posterior spinal fusion: a prospective study T2 - Spine (Phila Pa 1976) TI - Timing and predictors of return to short-term functional activity in adolescent idiopathic scoliosis after posterior spinal fusion: a prospective study VL - 39 ID - 4085 ER - TY - JOUR AB - BACKGROUND: Medical treatment for eliminating the side effects of cancer therapy may not always be efficacious. Acupuncture is one of the most widely accepted alternative and complementary therapies in use today. In this study, we investigated the efficacy of acupuncture in patients experiencing cancer treatment side effects, including nausea, vomiting, pain, poor sleep quality and anxiety. MATERIALS AND METHODS: A total of 45 inpatients who underwent chemotherapy between February and April 2013 in the Oncology Department of Numune Hospital were included in our study. Acupuncture was administered to the patients one day prior to chemotherapy, on the day of chemotherapy and one day after chemotherapy. The patients were evaluated on nausea, vomiting, pain, sleep quality and anxiety before the chemotherapy and on the 4th day of chemotherapy. RESULTS: Of the 45 patients included in the study, 18 (40%) were female and 27 (60%) were male. A total of 25 (55.6%) had an elementary school education; 32 patients (71%) had stage 4 cancer and were treated with palliative chemotherapy (the patient characteristics are shown in Table 1). Statistically significant decreases (p<0.001) in pain, nausea, vomiting, insomnia and anxiety scores were observed after the acupuncture treatment compared to baseline. There were no differences in the age, gender, education level, stage or metastasis levels between the patient groups whose symptoms improved or were unchanged. CONCLUSIONS: Our study showed that acupuncture has positive effects in cancer treatment patients who experience nausea, vomiting, pain, poor sleep quality and anxiety as side effects of chemotherapy. Chemotherapy-related side effects in cancer patients could be decreased by the concurrent use of acupuncture. AD - Traditional, Complementary and Alternative Medicine Department, Ministry of Health, Ankara, Turkey E-mail : demettas19691@hotmail.com. AN - 24815460 AU - Tas, D. AU - Uncu, D. AU - Sendur, M. A. AU - Koca, N. AU - Zengin, N. DO - 10.7314/apjcp.2014.15.7.3139 DP - NLM ET - 2014/05/13 IS - 7 KW - *Acupuncture Therapy Adult Aged Antineoplastic Agents/*adverse effects/therapeutic use Anxiety/therapy Female Humans Male Middle Aged Nausea/therapy Neoplasms/drug therapy/*therapy Pain Management/*methods Sleep Initiation and Maintenance Disorders/therapy Turkey Vomiting/therapy Young Adult LA - eng N1 - 2476-762x Tas, Demet Uncu, Dogan Sendur, Mehmet Ali Koca, Nuran Zengin, Nurullah Journal Article Thailand Asian Pac J Cancer Prev. 2014;15(7):3139-44. doi: 10.7314/apjcp.2014.15.7.3139. PY - 2014 SN - 1513-7368 SP - 3139-44 ST - Acupuncture as a complementary treatment for cancer patients receiving chemotherapy T2 - Asian Pac J Cancer Prev TI - Acupuncture as a complementary treatment for cancer patients receiving chemotherapy VL - 15 ID - 3815 ER - TY - JOUR AB - Objective: Headache is one of the most common neurologic problems in children and adolescents. Primary headache including migraine and tension-type headache comprises the vast majority of headaches and are associated with marked incidence, prevalence, and individual and social cost. We aimed to assess demographic characteristics and to compare some factors related to primary headaches in children/adolescents presented to neurology clinics of Tabriz University of Medical Sciences. Methods Children from 4 to 15 years of age with the diagnosis of primary headache (migraine or tension-type headaches) who presented to the neurology clinics affiliated to Tabriz University of Medical Sciences, Tabriz, Iran from March 2009 to October 2011 are included in this cross-sectional study. Data regarding the type of headache, history of atopy, peripartum asphyxia, and breast feeding, family history of headache and the socioeconomic status of the family were collected. The diagnosis was based on the international headache society diagnostic criteria for the primary headache disorders. Findings: One hundred ninety children (107 females) with primary headache (88 patients with migraine and 102 patients with tension type headache) enrolled in the study. Peripartum asphyxia, history of atopy, family history of headache and low socioeconomic status (SES) were more common in patients with migraine (P-values: 0.007, 0.01, 0.001, 0.003; respectively). Conclusion: Physicians need to extent their knowledge regarding the primary headaches. Peripartum asphyxia, history of atopy, headache in parents and low SES have been shown in the present study to be more prevalent in patients with migraine as compared to tension-type headache. AN - WOS:000326244800008 AU - Tavasoli, A. AU - Aghamohammadpoor, M. AU - Taghibeigi, M. DA - Oct IS - 5 N1 - Tavasoli, Azita Aghamohammadpoor, Mehran Taghibeigi, Meygol Tavasoli, Azita/0000-0002-9215-7077 2008-2150 PY - 2013 SN - 2008-2142 SP - 536-540 ST - Migraine and Tension-Type Headache in Children and Adolescents Presenting to Neurology Clinics T2 - Iranian Journal of Pediatrics TI - Migraine and Tension-Type Headache in Children and Adolescents Presenting to Neurology Clinics UR - ://WOS:000326244800008 VL - 23 ID - 2342 ER - TY - JOUR AB - There are currently no clinic-level quality of care metrics for outpatient pediatric oncology. We sought to develop a list of quality of care metrics for a leukemia-lymphoma (LL) clinic using a consensus process that can be adapted to other clinic settings. Medline-Ovid was searched for quality indicators relevant to pediatric oncology. A provisional list of 27 metrics spanning 7 categories was generated and circulated to a Consensus Group (CG) of LL clinic medical and nursing staff. A Delphi process comprising 2 rounds of ranking generated consensus on a final list of metrics. Consensus was defined as Z70% of CG members ranking a metric within 2 consecutive scores. In round 1, 19 of 27 (70%) metrics reached consensus. CG members' comments resulted in 4 new metrics and revision of 8 original metrics. All 31 metrics were included in round 2. Twenty-four of 31 (77%) metrics reached consensus after round 2. Thirteen were chosen for the final list based on highest scores and eliminating redundancy. These included: patient communication/education; pain management; delay in access to clinical psychology, documentation of chemotherapy, of diagnosis/extent of disease, of treatment plan and of follow-up scheme; referral to transplant; radiation exposure during follow-up; delay until chemotherapy; clinic cancellations; and school attendance. This study provides a model of quality metric development that other clinics may use for local use. The final metrics will be used for ongoing quality improvement in the LL clinic. AN - WOS:000394572000017 AU - Teichman, J. AU - Punnett, A. AU - Gupta, S. DA - Mar DO - 10.1097/mph.0000000000000656 IS - 2 N1 - Teichman, Jennifer Punnett, Angela Gupta, Sumit Gupta, Sumit/0000-0003-1334-3670; Teichman, Jennifer/0000-0002-7538-5772 1536-3678 PY - 2017 SN - 1077-4114 SP - 90-96 ST - Development of Quality Metrics to Evaluate Pediatric Hematologic Oncology Care in the Outpatient Setting T2 - Journal of Pediatric Hematology Oncology TI - Development of Quality Metrics to Evaluate Pediatric Hematologic Oncology Care in the Outpatient Setting UR - ://WOS:000394572000017 VL - 39 ID - 2106 ER - TY - JOUR AB - Patient Scenario: The patient presented is a high school baseball pitcher who was unable to throw because of shoulder pain. He subsequently failed nonoperative management but was able to return to pitching after surgery and successful rehabilitation. Clinical Outcomes Assessment: The Disabilities of Arm, Shoulder and Hand (DASH) and the Pennsylvania Shoulder Score (PENN) were selected as clinical outcome assessment tools to quantify the patient's perceived ability to perform common daily tasks and sport tasks and current symptoms such as pain and patient satisfaction. Clinical Decision Making: The DASH and PENN provide important information that can be used to target specific interventions, set appropriate patient goals, assess between-sessions changes in patient status, and quantify patients' functional loss. Clinical Bottom Line: Best clinical practice involves the use of clinical outcome assessment tools to garner an objective measure of the impact of a patient's disease process on functional expectations. This process should facilitate a patient-centered approach by clinicians while they select the optimal intervention strategies and establish prognostic timelines. AN - WOS:000287172700007 AU - Thigpen, C. AU - Shanley, E. DA - Feb DO - 10.1123/jsr.20.1.61 IS - 1 N1 - Thigpen, Charles Shanley, Ellen Si PY - 2011 SN - 1056-6716 SP - 61-73 ST - Clinical Assessment of Upper Extremity Injury Outcomes T2 - Journal of Sport Rehabilitation TI - Clinical Assessment of Upper Extremity Injury Outcomes UR - ://WOS:000287172700007 VL - 20 ID - 2509 ER - TY - JOUR AB - BACKGROUND: Nontraumatic low back pain (LBP) is a common emergency department (ED) complaint and can be caused by serious pathologies that require immediate intervention or that lead to death. OBJECTIVE: The primary goal of this study is to identify risk factors associated with serious pathology in adult nontraumatic ED LBP patients. METHODS: We conducted a health records review and included patients aged ≥ 16 years with nontraumatic LBP presenting to an academic ED from November 2009 to January 2010. We excluded those with previously confirmed nephrolithiasis and typical renal colic presentation. We collected 56 predictor variables and outcomes within 30 days. Outcomes were determined by tracking computerized patient records and performance of univariate analysis and recursive partitioning. RESULTS: There were 329 patients included, with a mean age of 49.3 years; 50.8% were women. A total of 22 (6.7%) patients suffered outcomes, including one death, five compression fractures, four malignancies, four disc prolapses requiring surgery, two retroperitoneal bleeds, two osteomyelitis, and one each of epidural abscess, cauda equina, and leaking abdominal aortic aneurysm graft. Risk factors identified for outcomes were: anticoagulant use (odds ratio [OR] 15.6; 95% confidence interval [CI] 4.2-58.5), decreased sensation on physical examination (OR 6.9; CI 2.2-21.2), pain that is worse at night (OR 4.3; CI 0.9-20.1), and pain that persists despite appropriate treatment (OR 2.2; CI 0.8-5.6). These four predictors identified serious pathology with 91% sensitivity (95% CI 70-98%) and 55% specificity (95% CI 54-56%). CONCLUSION: We successfully identified risk factors associated with serious pathology among ED LBP patients. Future prospective studies are required to derive a robust clinical decision rule. AD - Department of Emergency Medicine, University of Ottawa, Ottawa, Ontario, Canada; Ottawa Hospital Research Institute, The Ottawa Hospital, Ottawa, Ontario, Canada; Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada. Department of Emergency Medicine, University of Ottawa, Ottawa, Ontario, Canada. Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada. Ottawa Hospital Research Institute, The Ottawa Hospital, Ottawa, Ontario, Canada. Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada. AN - 24725822 AU - Thiruganasambandamoorthy, V. AU - Turko, E. AU - Ansell, D. AU - Vaidyanathan, A. AU - Wells, G. A. AU - Stiell, I. G. DA - Jul DO - 10.1016/j.jemermed.2013.08.140 DP - NLM ET - 2014/04/15 IS - 1 KW - Adolescent Adult Aged Aged, 80 and over Anastomotic Leak/diagnosis Anticoagulants/*adverse effects Aortic Aneurysm/surgery Emergency Service, Hospital Female Fractures, Compression/complications/diagnosis Hemorrhage/*chemically induced/complications/diagnosis Humans Hypesthesia/*etiology Intervertebral Disc Displacement/complications/diagnosis Low Back Pain/*etiology Male Middle Aged Neoplasms/*complications/diagnosis Osteomyelitis/complications/diagnosis Pain, Intractable/*etiology Polyradiculopathy/complications/diagnosis Retroperitoneal Space Risk Factors Sensitivity and Specificity Spinal Fractures/complications/diagnosis Vascular Grafting/adverse effects Young Adult emergency department low back pain nontraumatic outcomes risk stratification LA - eng N1 - Thiruganasambandamoorthy, Venkatesh Turko, Ekaterina Ansell, Dominique Vaidyanathan, Aparna Wells, George A Stiell, Ian G Journal Article Research Support, Non-U.S. Gov't United States J Emerg Med. 2014 Jul;47(1):1-11. doi: 10.1016/j.jemermed.2013.08.140. Epub 2014 Apr 13. PY - 2014 SN - 0736-4679 (Print) 0736-4679 SP - 1-11 ST - Risk factors for serious underlying pathology in adult emergency department nontraumatic low back pain patients T2 - J Emerg Med TI - Risk factors for serious underlying pathology in adult emergency department nontraumatic low back pain patients VL - 47 ID - 3810 ER - TY - JOUR AB - BACKGROUND: The frequency of chronic postsurgical pain (CPSP) after knee replacement remains high, but might be decreased by improvements to prevention. OBJECTIVES: To identify pre- and postsurgical factors predictive of CPSP 6 months after knee replacement. STUDY DESIGN: Single-center prospective observational study. SETTING: An orthopedic unit in a French hospital. METHODS: Consecutive patients referred for total or unicompartmental knee arthroplasty from March to July 2013 were prospectively invited to participate in this study. For each patient, we recorded preoperative pain intensity, anxiety and depression levels, and sensitivity and pain thresholds in response to an electrical stimulus. We analyzed OPRM1 and COMT single-nucleotide polymorphisms. Acute postoperative pain (APOP) in the first 5 days after surgery was modeled by a pain trajectory. Changes in the characteristics and consequences of the pain were monitored 3 and 6 months after surgery. Bivariate analysis and multivariate logistic regression were conducted to identify predictors of CPSP. RESULTS: We prospectively evaluated 104 patients in this study, 74 (28.8%) of whom reported CPSP at 6 months. Three preoperative factors were found to be associated with the presence of CPSP in multivariate logistic regression analysis: high school diploma level (OR = 3.83 [1.20 - 12.20]), consequences of pain in terms of walking ability, as assessed with the Brief Pain Inventory short form "walk" item (OR = 4.06 [1.18 - 13.94]), and a lack of physical activity in adulthood (OR = 4.01 [1.33 - 12.10]). One postoperative factor was associated with the presence of CPSP: a high-intensity APOP trajectory. An association of borderline statistical significance was found with the A allele of the COMT gene (OR = 3.4 [0.93 - 12.51]). Two groups of patients were identified on the basis of their APOP trajectory: high (n = 28, 26%) or low (n = 80, 74%) intensity. Patients with high-intensity APOP trajectory had higher anxiety levels and were less able to walk before surgery (P < 0.05). LIMITATIONS: This was a single-center study and the sample may have been too small for the detection of some factors predictive of CPSP or to highlight the role of genetic factors. CONCLUSION: Our findings suggest that several preoperative and postoperative characteristics could be used to facilitate the identification of patients at high risk of CPSP after knee surgery. All therapeutic strategies decreasing APOP, such as anxiety management or performing knee replacement before the pain has a serious effect on ability to walk, may help to decrease the risk of CPSP. Further prospective studies testing specific management practices, including a training program before surgery, are required. AD - Unité INSERM 987, Physiopathology et clinical pain pharmacology, Ambroise Paré Hospital, Boulogne Billancourt F-92100; Assistance Publique-Hôpitaux de Paris, Lariboisière Hospital, Unit of Therapeutic Research, Department of Internal Medicine, Paris F-75010, France. Assistance Publique-Hôpitaux de Paris, Hôtel Dieu Hospital, Biostatistics and Epidemiology Department; INSERM, U1178, Mental Health and Public Health, Paris-Sud and Paris Descartes Universities, Paris-75005, France. Unité INSERM 987, Physiopathology et clinical pain pharmacology, Ambroise Paré Hospital, Boulogne Billancourt; Center for the Evaluation and Treatement of Pain, Hôtel Dieu Hospital, Paris-F75001, France. Anesthesia-reanimation Unit, Lariboisiere Hospital, Paris-F75010, France. INSERM U1144, Variability of the response to psychotropic drugs, Paris Descartes University and Paris Diderot University, Paris-75005, France. Orthopaedic and Traumatology Unit, Lariboisière Hospital, Paris-F75010, France. Assistance Publique-Hôpitaux de Paris, Lariboisière Hospital, Unit of Therapeutic Research, Department of Internal Medicine, Paris F-75010, France; INSERM U1144, Variability of the response to psychotropic drugs, Paris Descartes University and Paris Diderot University, Paris-75005, France. Unité INSERM 987, Physiopathology et clinical pain pharmacology, Ambroise Paré Hospital, Boulogne Billancourt F-92100, France; Center for the Evaluation and Treatement of Pain, Hôtel Dieu Hospital, Paris-F75001, France. AN - 27389116 AU - Thomazeau, J. AU - Rouquette, A. AU - Martinez, V. AU - Rabuel, C. AU - Prince, N. AU - Laplanche, J. L. AU - Nizard, R. AU - Bergmann, J. F. AU - Perrot, S. AU - Lloret-Linares, C. DA - Jul DP - NLM ET - 2016/07/09 IS - 5 KW - Aged Arthroplasty, Replacement, Knee/*adverse effects *Chronic Pain/diagnosis/etiology/genetics Female Humans Male Middle Aged *Pain, Postoperative/diagnosis/etiology/genetics Prospective Studies Risk Factors LA - eng N1 - 2150-1149 Thomazeau, Josephine Rouquette, Alexandra Martinez, Valeria Rabuel, Christophe Prince, Natalie Laplanche, Jean-Louis Nizard, Remy Bergmann, Jean-Francois Perrot, Serge Lloret-Linares, Celia Journal Article Observational Study United States Pain Physician. 2016 Jul;19(5):E729-41. PY - 2016 SN - 1533-3159 SP - E729-41 ST - Predictive Factors of Chronic Post-Surgical Pain at 6 Months Following Knee Replacement: Influence of Postoperative Pain Trajectory and Genetics T2 - Pain Physician TI - Predictive Factors of Chronic Post-Surgical Pain at 6 Months Following Knee Replacement: Influence of Postoperative Pain Trajectory and Genetics VL - 19 ID - 3650 ER - TY - JOUR AB - BACKGROUND: Race differences in chronic conditions and disability are well established; however, little is known about the association between specific chronic conditions and disability in African Americans. This is important because African Americans have higher rates and earlier onset of both chronic conditions and disability than white Americans. METHODS: We examined the relationship between chronic conditions and disability in 602 African Americans aged 50 years and older in the Baltimore Study of Black Aging. Disability was measured using self-report of difficulty in activities of daily living (ADL). Medical conditions included diagnosed self-reports of asthma, depressive symptoms, arthritis, cancer, diabetes, cardiovascular disease (CVD), stroke, and hypertension. RESULTS: After adjusting for age, high school graduation, income, and marital status, African Americans who reported arthritis (women: odds ratio (OR)=4.87; 95% confidence interval(CI): 2.92-8.12; men: OR=2.93; 95% CI: 1.36-6.30) had higher odds of disability compared to those who did not report having arthritis. Women who reported major depressive symptoms (OR=2.59; 95% CI: 1.43-4.69) or diabetes (OR=1.83; 95% CI: 1.14-2.95) had higher odds of disability than women who did not report having these conditions. Men who reported having CVD (OR=2.77; 95% CI: 1.03-7.41) had higher odds of disability than men who did not report having CVD. CONCLUSIONS: These findings demonstrate the importance of chronic conditions in understanding disability in African Americans and how it varies by gender. Also, these findings underscore the importance of developing health promoting strategies focused on chronic disease prevention and management to delay or postpone disability in African Americans. PUBLICATION INDICES: Pubmed, Pubmed Central, Web of Science database. AD - Hopkins Center for Health Disparities Solutions, Johns Hopkins Bloomberg School of Public Health, Department of Health, Behavior, and Society, Johns Hopkins Bloomberg School of Public Health, Center for Biobehavioral Health Disparities Research, Duke University. Electronic address: rthorpe@jhu.edu. Hopkins Center for Health Disparities Solutions, Johns Hopkins Bloomberg School of Public Health. Johns Hopkins School of Nursing, Johns Hopkins University. Duke University School of Nursing, Duke University. Hopkins Center for Health Disparities Solutions, Johns Hopkins Bloomberg School of Public Health, Center for Biobehavioral Health Disparities Research, Duke University, Johns Hopkins School of Nursing, Johns Hopkins University. Center for Biobehavioral Health Disparities Research, Duke University, Department of Psychology and Neuroscience, Duke University. AN - 26928493 AU - Thorpe, R. J., Jr. AU - Wynn, A. J. AU - Walker, J. L. AU - Smolen, J. R. AU - Cary, M. P. AU - Szanton, S. L. AU - Whitfield, K. E. C2 - PMC5809332 C6 - NIHMS939903 DA - Feb DO - 10.1016/j.jnma.2015.12.012 DP - NLM ET - 2016/03/02 IS - 1 KW - *Activities of Daily Living African Americans/psychology/*statistics & numerical data Aging/physiology/psychology Baltimore Chronic Disease/epidemiology/*ethnology/psychology Chronic Pain/*complications/epidemiology/psychology Comorbidity Depressive Disorder, Major/epidemiology *Disabled Persons European Continental Ancestry Group Female Humans Male Middle Aged United States *African Americans *chronic conditions *disability *health disparities *men LA - eng N1 - 1943-4693 Thorpe, Roland J Jr Wynn, Anastasia J Walker, Janiece L Smolen, Jenny R Cary, Michael P Szanton, Sarah L Whitfield, Keith E P60 MD000214/MD/NIMHD NIH HHS/United States R01 AG024108/AG/NIA NIH HHS/United States Journal Article Research Support, N.I.H., Extramural J Natl Med Assoc. 2016 Feb;108(1):90-8. doi: 10.1016/j.jnma.2015.12.012. PY - 2016 SN - 0027-9684 (Print) 0027-9684 SP - 90-8 ST - Relationship Between Chronic Conditions and Disability in African American Men and Women T2 - J Natl Med Assoc TI - Relationship Between Chronic Conditions and Disability in African American Men and Women VL - 108 ID - 3163 ER - TY - JOUR AB - Introduction The 2011 IOM report stated that pain management in children is often lacking especially during routine medical procedures. The purpose of this review is to bring a developmental lens to the challenges in assessment and non-pharmacologic treatment of pain in young children. Method: A synthesis of the findings from an electronic search of PubMed and the university library using the keywords pain, assessment, treatment, alternative, complementary, integrative, infant, toddler, preschool, young, pediatric, and child was completed. A targeted search identified additional sources for best evidence. Results: Assessment of developmental cues is essential. For example, crying, facial expression, and body posture are behaviors in infancy that indicate pain: however in toddlers these same behaviors are not necessarily indicative of pain. Preschoolers need observation scales in combination with self-report while for older children self-report is the gold standard. Pain management in infants includes swaddling and sucking. However for toddlers, preschoolers and older children, increasingly sophisticated distraction techniques such as easily implemented non-pharmacologic painmanagement strategies include reading stories, watching cartoons, or listening to music. Discussion: A developmental approach to assessing and treating pain is critical. Swaddling, picture books, or blowing bubbles are easy and effective when used at the appropriate developmental stage and relieve both physical and emotional pain. Untreated pain in infants and young childrenmay lead to increased pain perception and chronic pain in adolescents and adults. Continued research in the non-pharmacological treatment of pain is an important part of the national agenda. (C) 2016 Elsevier Inc. All rights reserved. AN - WOS:000368560700002 AU - Thrane, S. E. AU - Wanless, S. AU - Cohen, S. M. AU - Danford, C. A. DA - Jan-Feb DO - 10.1016/j.pedn.2015.09.002 IS - 1 N1 - Thrane, Susan E. Wanless, Shannon Cohen, Susan M. Danford, Cynthia A. Thrane, Susan/E-9888-2016 Cohen, Susan/0000-0002-3860-4681; Thrane, Susan/0000-0001-6654-9133; Wanless, Shannon/0000-0003-1766-6418 PY - 2016 SN - 0882-5963 SP - E23-E32 ST - The Assessment and Non-Pharmacologic Treatment of Procedural Pain From Infancy to School Age Through a Developmental Lens: A Synthesis of Evidence With Recommendations T2 - Journal of Pediatric Nursing-Nursing Care of Children & Families TI - The Assessment and Non-Pharmacologic Treatment of Procedural Pain From Infancy to School Age Through a Developmental Lens: A Synthesis of Evidence With Recommendations UR - ://WOS:000368560700002 VL - 31 ID - 2194 ER - TY - JOUR AB - According studies run during four years (1992-1995) in the Pediatric Unit of Libreville Hospital, to determine importance and features of sickle-cell disease in children in Gabon, profit and mode of regular follow-up, data of hospitalisation and management of children with sickle-cell disease were found as follow: Sickle-cell disease is third rank of admission motivations (13% of total admissions), and first after 4 years. Mortality is 8.4% of total mortality. Main causes of hospitalisation were acute anemia, painful crisis, and bacterial infections. Half of children had no medical follow-up, third was regularly checked, the remaining very irregularly, 80% of died children had no medical follow-up. A survey with an ambulatory taking-care which concerned 210 kids regularly checked, shows theses outcomes: the social families background was either medium or disavow. More than half of children were detected before one year, mainly by complication. Third had splenomegaly, 70% hepatomegaly and 40% were icteric. Based on 103 children tested for HIV, only 2 were found positive, but 22% were positive for HBs Ag. Growth, puberty and school retardation is a supplementary social handicap. A comparative with other cohorts must headlight genetic and personal environing matters. Unit of management of sickle-cell disease, annexed to a Pediatric Unit, provided that official acknowledgement, seems to be the best solution, as regards cost/efficiency, in the local context. AD - Service de pédiatrie B, Centre Hospitalier de Libreville, Gabon. AN - 9432415 AU - Thuilliez, V. AU - Vierin, Y. DA - Mar DP - NLM ET - 1997/03/01 IS - 1 KW - Africa, Central Anemia, Sickle Cell/*epidemiology/mortality/therapy Child Child, Preschool Female Hospitals Humans Infant Infant, Newborn Male *Pediatrics LA - fre N1 - Thuilliez, V Vierin, Y English Abstract Journal Article Research Support, Non-U.S. Gov't France Sante Publique. 1997 Mar;9(1):45-60. OP - Le poids de la drépanocytose en milieu pédiatrique au Gabon. PY - 1997 SN - 0995-3914 (Print) 0995-3914 SP - 45-60 ST - [The importance of sickle cell anemia in a pediatric environment in Gabon] T2 - Sante Publique TI - [The importance of sickle cell anemia in a pediatric environment in Gabon] VL - 9 ID - 3813 ER - TY - JOUR AB - OBJECTIVE: To evaluate the frequency of menorrhagia and endometriosis in female migraineurs compared to age-matched women without headache. BACKGROUND: Migraine predominantly affects women of childbearing age and is often associated with the menstrual period, yet there is a paucity of data regarding the relationship of migraine and menstrual disorders. METHODS: Women diagnosed with migraine, using International Headache Society criteria and an age- and sex-matched control group, were administered a semistructured questionnaire regarding migraine and migraine-related disability, menstrual history, other bleeding history, vascular event history, and vascular risk factors. RESULTS: Fifty female migraineurs between the ages of 22 and 50 years and 52 age-matched women (mean age 37 years) were enrolled in the study. Similar proportions of women in each group reported using hormone contraceptives (30% vs. 33%, P = .77) and hormone replacement therapy (12% vs. 8%, P = .69). The proportions presently menstruating (64 % vs. 80%, P = .20) and status after hysterectomy were similar (24% vs. 14%, P = .84). Menorrhagia (defined as at least three consecutive heavy periods), both current and prior, was more commonly reported in migraineurs (63% vs. 37%, P = .009), with higher likelihood of staining clothes by menses (35% vs. 8%, P = .003), and significant impact of menses on activities of daily living (on a 10-point Likert scale) with work/school participation (P = .02), family activities (P < .0001), sleep (P = .003), life enjoyment (P = .001), mood (P = .02), and overall quality of life (P = .003). Endometriosis, which may be associated with menorrhagia, was also more commonly diagnosed in the migraineurs (30% vs. 4%, P = .001). The migraineurs more frequently described bruising (40% vs. 10%, P < .001) and rectal bleeding (18% vs. 2%, P = .017) but not more serious bleeding problems. Nonsteroidal anti-inflammatory drug (NSAID) use was more frequent in the migraine group (28% vs. 12%, P = .036), and significance for increased menorrhagia, endometriosis, menstrual interference, and bruising was maintained, even when controlling for the use of NSAIDs. With logistic regression, menorrhagia was significantly associated with migraine, adjusted odds ratio (OR) = 2.8 (95% CI 1.2 to 6.5), and with endometriosis, adjusted OR = 10.5 (95% CI 2.2 to 51.4). There were no differences in vascular events and risk factors, except for trends of increased hypertension (25% vs. 10%, P = .05), transient ischemic attack/stroke (10% vs. 2%, P = .08), and Raynaud's disease (10% vs. 2%, P = .08) in the migraineurs. CONCLUSION: Women with migraine have a higher frequency of menorrhagia, endometriosis, and associated psychosocial consequences. These findings suggest that there should be further study of factors influencing endometriosis and menstrual blood flow, such as eicosanoids and platelet function, in migraineurs. AD - Department of Neurology, Medical College of Ohio, Toledo 43614, USA. AN - 16618258 AU - Tietjen, G. E. AU - Conway, A. AU - Utley, C. AU - Gunning, W. T. AU - Herial, N. A. DA - Mar DO - 10.1111/j.1526-4610.2006.00290.x DP - NLM ET - 2006/04/19 IS - 3 KW - Adult Endometriosis/*complications Female Humans Menorrhagia/*complications Middle Aged Migraine Disorders/*complications LA - eng N1 - Tietjen, Gretchen E Conway, Anita Utley, Christine Gunning, William T Herial, Nabeel A Journal Article United States Headache. 2006 Mar;46(3):422-8. doi: 10.1111/j.1526-4610.2006.00290.x. PY - 2006 SN - 0017-8748 (Print) 0017-8748 SP - 422-8 ST - Migraine is associated with menorrhagia and endometriosis T2 - Headache TI - Migraine is associated with menorrhagia and endometriosis VL - 46 ID - 3861 ER - TY - CHAP A2 - Adam, M. P. A2 - Ardinger, H. H. A2 - Pagon, R. A. A2 - Wallace, S. E. A2 - Bean, L. J. H. A2 - Mirzaa, G. A2 - Amemiya, A. AB - CLINICAL DESCRIPTION: In adults, X-linked spondyloepiphyseal dysplasia tarda (X-linked SEDT) is characterized by disproportionately short stature with short trunk and arm span significantly greater than height. At birth, affected males are normal in length and have normal body proportions. Affected males exhibit linear growth deficiency beginning around age six to eight years. Final adult height is typically 137-163 cm. Progressive joint and back pain with osteoarthritis ensues; hip, knee, and shoulder joints are commonly involved but to a variable degree. Hip replacement is often required as early as age 40 years. Interphalangeal joints are typically spared. Motor and cognitive milestones are normal. DIAGNOSIS/TESTING: The clinical diagnosis of X-linked SEDT can be established in a male proband with characteristic radiographic findings (which typically appear prior to puberty) including: multiple epiphyseal abnormalities, platyspondyly with characteristic superior and inferior "humping" seen on lateral view, scoliosis, hypoplastic odontoid process, short femoral necks, and coxa vara; evidence of premature osteoarthritis appears in young adulthood. The molecular diagnosis of X-linked SEDT can be established in a male proband with suggestive findings and a hemizygous pathogenic variant in TRAPPC2 identified by molecular genetic testing. The molecular diagnosis of X-linked SEDT can be established in a female proband with osteoarthritis and a heterozygous pathogenic variant in TRAPPC2 identified by molecular genetic testing. MANAGEMENT: Treatment of manifestations: Treatment for scoliosis and kyphoscoliosis per orthopedic surgeon; surgical intervention may include spine surgery (correction of scoliosis or kyphosis). Pain management as needed for osteoarthritis; joint replacement (hip, knee, shoulder) as needed. Surveillance: Cervical spine films prior to school age and before any surgical procedure involving general anesthesia to assess for clinically significant odontoid hypoplasia. Annual follow up for assessment scoliosis and joint pain. Agents/circumstances to avoid: Extreme neck flexion and extension in individuals with odontoid hypoplasia. Activities and occupations that place undue stress on the spine and weight-bearing joints. Evaluation of relatives at risk: Presymptomatic testing in males at risk may obviate unnecessary diagnostic testing for other causes of short stature and/or osteoarthritis. GENETIC COUNSELING: By definition, X-linked SEDT is inherited in an X-linked manner. When performed, molecular genetic testing of all mothers of affected sons determined that regardless of family history all were carriers of a pathogenic variant in TRAPPC2. Carrier females are at a 50% risk of transmitting the TRAPPC2 pathogenic variant in each pregnancy: males who inherit the pathogenic variant will be affected; females who inherit the pathogenic variant will be carriers and will not be affected. None of the sons of an affected male will be affected; all daughters will be carriers of the TRAPPC2 pathogenic variant. Carrier testing of at-risk female relatives and prenatal testing for pregnancies at increased risk are possible if the pathogenic variant in the family has been identified. AD - Department of Genetics, Southern California Permanente Medical Group, Los Angeles, California AN - 20301324 AU - Tiller, G. E. CY - Seattle (WA) LA - eng N1 - Adam, Margaret P Ardinger, Holly H Pagon, Roberta A Wallace, Stephanie E Bean, Lora JH Mirzaa, Ghayda Amemiya, Anne Tiller, George E Review Book Chapter NBK1145 [bookaccession] PB - University of Washington, Seattle Copyright © 1993-2021, University of Washington, Seattle. GeneReviews is a registered trademark of the University of Washington, Seattle. All rights reserved. PY - 1993 ST - X-Linked Spondyloepiphyseal Dysplasia Tarda T2 - GeneReviews(®) TI - X-Linked Spondyloepiphyseal Dysplasia Tarda ID - 4228 ER - TY - JOUR AB - Background: Patients with concussion may present with cervical spine impairments, therefore accurate characterization of cervical post-concussion impairments is needed to develop targeted physical therapy interventions. Purpose: To characterize the type, frequency and severity of cervical impairments in children and adolescents referred for physical therapy after concussion. Study design: Retrospective, descriptive study Methods: A retrospective analysis was conducted for 73 consecutive children and adolescents who received cervical physical therapy following a concussion. Data was classified into six broad categories. The frequency and intensity of cervical impairments within and across the categories was reported. Results: Ninety percent of patients demonstrated impairments in at least three out of five assessment categories whereas 55% demonstrated impairments in at least four out five assessment categories. Of the five assessment categories, posture (99%) and myofascial impairment (98%) demonstrated highest impairment frequency followed by joint mobility (86%) and muscle strength (62%). Cervical joint proprioception was the least commonly evaluated assessment category. Conclusion: High prevalence of cervical spine impairments was observed in the subjects included in this study with muscle tension, joint mobility, and muscle strength being most commonly affected. The categories of impairments examined in this cohort were consistent with the recommendations of the most recent clinical practice guidelines for neck pain. This study provides preliminary data to support the framework for a cervical spine evaluation tool in children and adolescents following concussion. AN - WOS:000470023600013 AU - Tiwari, D. AU - Goldberg, A. AU - Yorke, A. AU - Marchetti, G. F. AU - Alsalaheen, B. DA - Apr DO - 10.26603/ijspt20190282 IS - 2 N1 - Tiwari, Devashish Goldberg, Allon Yorke, Amy Marchetti, Gregory F. Alsalaheen, Bara Yorke, Amy/Q-4091-2019 Yorke, Amy/0000-0003-4998-0313 PY - 2019 SN - 2159-2896 SP - 282-295 ST - CHARACTERIZATION OF CERVICAL SPINE IMPAIRMENTS IN CHILDREN AND ADOLESCENTS POST-CONCUSSION T2 - International Journal of Sports Physical Therapy TI - CHARACTERIZATION OF CERVICAL SPINE IMPAIRMENTS IN CHILDREN AND ADOLESCENTS POST-CONCUSSION UR - ://WOS:000470023600013 VL - 14 ID - 1934 ER - TY - JOUR AB - BACKGROUND: Surgical treatment of patellofemoral instability can successfully diminish episodes of subluxation and dislocation, as well as symptoms of pain and instability. HYPOTHESIS: Surgical treatment of lateral patellar instability in a strictly athletic population will facilitate return to sports. STUDY DESIGN: Case series; Level of evidence, 4. METHODS: From 1999 to 2004, 41 Fulkerson osteotomies combined with an arthroscopic lateral release were performed in 34 athletes for patellofemoral instability. Three patients were lost to follow-up. All patients participated in sports at least 3 times per week in at least one sport for 4 months of the year. There were 4 male and 30 female patients; 7 patients underwent bilateral, staged procedures. There were 14 high school, 12 collegiate, and 8 recreational athletes. Results were obtained by an independent examiner. RESULTS: The mean age was 20.05 years (range, 14-54 years) with a mean follow-up of 46 months (range, 22-71 months). Patients averaged 1.3 dislocations before reconstruction (range, 0-6). The average Lysholm score was 91.8 (range, 67-100) at follow-up. The International Knee Documentation Committee (IKDC) scores were A (normal) in 27 knees, B (near normal) in 12, and C (abnormal) in 2. Seventeen patients had symptomatic hardware removed at an average of 8 months. There were 2 complications: one saphenous neuroma that resolved, and one recurrent dislocation in a patient later diagnosed with Ehlers-Danlos syndrome. CONCLUSION: This series is the largest to date documenting the successful treatment of patellofemoral instability in athletes with concomitant Fulkerson osteotomy and arthroscopic lateral release. Forty-nine percent of patients in our series required removal of screws from the osteotomy site. AD - Department of Orthopaedic Surgery, Hospital of the University of Pennsylvania, Penn Sports Medicine, Philadelphia, Pennsylvania 15203, USA. AN - 20212100 AU - Tjoumakaris, F. P. AU - Forsythe, B. AU - Bradley, J. P. DA - May DO - 10.1177/0363546509357682 DP - NLM ET - 2010/03/10 IS - 5 KW - Adolescent Adult Arthroscopy/methods Athletic Injuries/*surgery Ehlers-Danlos Syndrome/diagnosis Female Humans Joint Instability/*surgery Male Middle Aged Orthopedic Procedures/*methods Osteotomy/*methods Patellar Dislocation/diagnosis Patellofemoral Joint/*surgery Postoperative Complications/diagnosis Prospective Studies Range of Motion, Articular Reconstructive Surgical Procedures/*methods Recovery of Function Recurrence Treatment Outcome Young Adult LA - eng N1 - 1552-3365 Tjoumakaris, Fotios Paul Forsythe, Brian Bradley, James P Journal Article United States Am J Sports Med. 2010 May;38(5):992-9. doi: 10.1177/0363546509357682. Epub 2010 Mar 8. PY - 2010 SN - 0363-5465 SP - 992-9 ST - Patellofemoral instability in athletes: treatment via modified Fulkerson osteotomy and lateral release T2 - Am J Sports Med TI - Patellofemoral instability in athletes: treatment via modified Fulkerson osteotomy and lateral release VL - 38 ID - 4075 ER - TY - JOUR AB - AIMS OF THE STUDY: Given the long history of underestimating chronic pain in children and adolescents, we lack valid data on its assessment and treatment. The psychological and economic burden for patients, their families and society is substantial. The aim of this study was to assess patient characteristics of the first ambulatory interdisciplinary clinic for children and adolescents with chronic pain in Switzerland and compare them with data from other international centres. METHODS: All patients of the ambulatory interdisciplinary pain clinic at the University Children's Hospital in Basel during the period from 4 January 2012 to 4 July 2016 were included in this retrospective study. Data were collected from the patients' medical records and from a questionnaire, which the patients and their parents received and completed in advance of their first visit. Demographic information, pain, referral, social environment, therapies and school absences of the patients were statistically analysed with means, percentages, 95% confidence intervals (CIs) and standard deviations (SDs). RESULTS: Of the 135 patients included in this study, 80% were female and the mean age of all patients was 13.95 years (95% CI 13.5-14.4). The commonest pain presentations were: musculoskeletal (38%, 95% CI 0.30-0.46), back (25%, 95% CI 0.18-0.33), multiple regions (21%, 95% CI 0.15-0.28) and headache (7%, 95% CI 0.03-0.12). Mean duration of pain until the patients came to the clinic was 24.5 months (95% CI 19.82-29.22). Physiotherapy (71%, 95% CI 0.63-0.79) and non-opioids (50%, 95% CI 0.42-0.59) were the most used therapies before the first meeting. Psychotherapy (52%, 95% CI 0.44-0.61), most often using a psychosomatic therapeutic approach (psychosomatic therapy) 34% (95% CI 0.26-0.42), physiotherapy (36%, 95% CI 0.27-0.44) and non-opioids (33%, 95% CI 0.25-0.42) afterwards. The mean number of school absences during the last month before the first visit was 5.1 days per month (95% CI 3.48-6.73). The parents of our study participants suffered more often from psychiatric diseases than the mean Swiss population. CONCLUSIONS: The average of more than 2 years of pain before referral to the clinic seems to be a long time. Assuming that specialised support is mandatory for young patients with complex pain syndromes, the referral time should be reduced. Furthermore, patients with headache were underrepresented in Basel compared with other centres. Interestingly, in our study, patients' parents suffered more often from psychiatric diseases than the mean Swiss population. AN - WOS:000465026000005 AU - Tobias, S. AU - Dominik, P. AU - Andreas, W. AU - Wilhelm, R. C7 - w20073 DA - Apr DO - 10.4414/smw.2019.20073 N1 - Tobias, Schneider Dominik, Pfister Andreas, Woerner Wilhelm, Ruppen 1424-3997 PY - 2019 SN - 1424-7860 ST - Characteristics of children and adolescents at the Switzerland-wide first ambulatory interdisciplinary pain clinic at the University Children's Hospital Basel - a retrospective study T2 - Swiss Medical Weekly TI - Characteristics of children and adolescents at the Switzerland-wide first ambulatory interdisciplinary pain clinic at the University Children's Hospital Basel - a retrospective study UR - ://WOS:000465026000005 VL - 149 ID - 1929 ER - TY - JOUR AB - S1 Health literacy and health education in adolescence Catarina Cardoso Tomás S2 The effect of a walking program on the quality of life and well-being of people with schizophrenia Emanuel Oliveira, D. Sousa, M. Uba-Chupel, G. Furtado, C. Rocha, A. Teixeira, P. 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César, Mariana Poço, David Ventura, Raquel Loura, Pedro Gomes, Catarina Gomes, Cláudia Silva, Elsa Melo, João Lindo P58 Dating violence among young adolescents Joana Domingos, Zaida Mendes, Susana Poeta, Tiago Carvalho, Catarina Tomás, Helena Catarino, Mª Anjos Dixe P59 Physical activity and motor memory in pedal dexterity André Ramalho, António Rosado, Pedro Mendes, Rui Paulo, Inês Garcia, João Petrica P60 The effects of whole body vibration on the electromyographic activity of thigh muscles Sandra Rodrigues, Rui Meneses, Carlos Afonso, Luís Faria, Adérito Seixas P61 Mental health promotion in the workplace Marina Cordeiro, Paulo Granjo, José C. Gomes P62 Influence of physical exercise on the self-perception of body image in elderly women: A systematic review of qualitative studies Nelba R. Souza, Guilherme E. Furtado, Saulo V. Rocha, Paula Silva, Joana Carvalho O109 Psychometric properties of the Portuguese version of the Éxamen Geronto-Psychomoteur (P-EGP) Marina Ana Morais, Sofia Santos, Paula Lebre, Ana Antunes O110 Symptoms of depression in the elderly population of Portugal, Spain and Italy António Calha O111 Emotion regulation strategies and psychopathology symptoms: A comparison between adolescents with and without deliberate self-harm Ana Xavier, Marina Cunha, José Pinto-Gouveia O112 Prevalence of physical disability in people with leprosy Liana Alencar, Madalena Cunha, António Madureira O113 Quality of life and self-esteem in type 1 and type 2 diabetes mellitus patients Ilda Cardoso, Ana Galhardo, Fernanda Daniel, Vítor Rodrigues O114 Cross-cultural comparison of gross motor coordination in children from Brazil and Portugal Leonardo Luz, Tatiana Luz, Maurício R. Ramos, Dayse C. Medeiros, Bruno M. Carmo, André Seabra, Cristina Padez, Manuel C. Silva O115 Electrocardiographic differences between African and Caucasian people António Rodrigues, Patrícia Coelho, Alexandre Coelho O116 Factors associated with domestic, sexual and other types of violence in the city of Palhoça - Brazil Madson Caminha, Filipe Matheus, Elenice Mendes, Jony Correia, Marcia Kretzer O117 Tinnitus prevalence study of users of a hospital of public management - Spain Francisco J. Hernandez-Martinez, Juan F. Jimenez-Diaz, Bienvendida C. Rodriguez-De-Vera, Carla Jimenez-Rodriguez, Yadira Armas-Gonzalez O118 Difficulties experienced by parents of children with diabetes mellitus of preschool age in therapeutic and nutritional management Cátia Rodrigues, Rosa Pedroso O119 E-mental health - “nice to have” or “must have”? Exploring the attitudes towards e-mental health in the general population Jennifer Apolinário-Hagen, Viktor Vehreschild O120 Violence against children and adolescents and the role of health professionals: Knowing how to identify and care Milene Veloso, Celina Magalhães, Isabel Cabral, Maira Ferraz O121 Marital violence. A study in the Algarve population Filipe Nave, Emília Costa, Filomena Matos, José Pacheco O122 Clinical factors and adherence to treatment in ischemic heart disease António Dias, Carlos Pereira, João Duarte, Madalena Cunha, Daniel Silva O123 Can religiosity improve optimism in participants in states of illness, when controlling for life satisfaction? Lisete M. Mónico, Valentim R. Alferes, Mª São João Brêda, Carla Carvalho, Pedro M. Parreira O124 Empowerment, knowledge and quality of life of people with diabetes type 2 in the Alto Minho Health Local Unit Mª Carminda Morais, Pedro Ferreira, Rui Pimenta, José Boavida O125 Antihypertensive therapy adherence among hypertensive patients from Bragança county, Portugal Isabel C. Pinto, Tânia Pires, Catarina Silva O126 Subjective perception of sexual achievement - An exploratory study on people with overweight Maria Ribeiro, Maria Viega-Branco, Filomena Pereira, Ana Mª Pereira O127 Physical activity level and associated factors in hypertensive individuals registered in the family health strategy of a basic health unit from the city of Palhoça, Santa Catarina, Brazil Fabrícia M. Almeida, Gustavo L. Estevez, Sandra Ribeiro, Marcia R. Kretzer O128 Perception of functional fitness and health in non-institutionalised elderly from rural areas Paulo V. João, Paulo Nogueira, Sandra Novais, Ana Pereira, Lara Carneiro, Maria Mota O129 Medication adherence in patients with type 2 diabetes mellitus treated at primary health care in Coimbra Rui Cruz, Luiz Santiago, Carlos Fontes-Ribeiro O130 Multivariate association between body mass index and multi-comorbidities in elderly people living in low socio-economic status context Guilherme Furtado, Saulo V. Rocha, André P. Coutinho, João S. Neto, Lélia R. Vasconcelos, Nelba R. Souza, Estélio Dantas O131 Metacognition, rumination and experiential avoidance in Borderline Personality Disorder Alexandra Dinis, Sérgio Carvalho, Paula Castilho, José Pinto-Gouveia O132 Health issues in a vulnerable population: nursing consultation in a public bathhouse in Lisbon Alexandra Sarreira-Santos, Amélia Figueiredo, Lurdes Medeiros-Garcia, Paulo Seabra O133 The perception of quality of life in people with multiple sclerosis accompanied in External Consultation of the Local Health Unit of Alto Minho Rosa Rodrigues, Mª Carminda Morais, Paula O. Fernandes O134 Representation of interaction established between immigrant women and nurse during pregnancy to postpartum, from the perspective of immigrant women Conceição Santiago, Mª Henriqueta Figueiredo, Marta L. Basto O135 Illness perceptions and medication adherence in hypertension Teresa Guimarães, André Coelho, Anabela Graça, Ana M. Silva, Ana R. Fonseca O136 A Portuguese study on adults’ intimate partner violence, interpersonal trust and hope Luz Vale-Dias, Bárbara Minas, Graciete Franco-Borges P63 QOL’ predictors of people with intellectual disability and general population Cristina Simões, Sofia Santos P64 Content validation of the Communication Disability Profile (CDP) - Portuguese Version Ana Serra, Maria Matos, Luís Jesus P65 Study of biochemical and haematological changes in football players Ana S. Tavares, Ana Almeida, Céu Leitão, Edna Varandas, Renato Abreu, Fernando Bellém P66 Body image dissatisfaction in inflammatory bowel disease: exploring the role of chronic illness-related shame Inês A. Trindade, Cláudia Ferreira, José Pinto-Gouveia, Joana Marta-Simões P67 Obesity and sleep in the adult population - a systematic review Odete Amaral, Cristiana Miranda, Pedro Guimarães, Rodrigo Gonçalves, Nélio Veiga, Carlos Pereira P68 Frequency of daytime sleepiness and obstructive sleep apnea risk in COPD patients Tânia C. Fleig, Elisabete A. San-Martin, Cássia L. Goulart, Paloma B. Schneiders, Natacha F. Miranda, Lisiane L. Carvalho, Andrea G. Silva P69 Working with immigrant-origin clients: discourses and practices of health professionals Joana Topa, Conceição Nogueira, Sofia Neves P70 Systemic Lupus Erythematosus – what are audiovestibular changes? Rita Ventura, Cristina Nazaré P71 Mental disorders in the oldest old: findings from the Portuguese national hospitalization database Daniela Brandão, Alberto Freitas, Óscar Ribeiro, Constança Paúl P72 Recurrence analysis in postural control in children with cerebral palsy Cristiana Mercê, Marco Branco, Pedro Almeida, Daniela Nascimento, Juliana Pereira, David Catela P73 The experience of self-care in the elderly with COPD: contributions to reflect proximity care Helga Rafael P74 Culturally competent nurses: managing unpredictability in clinical practice with immigrants Alcinda C. Reis O137 Paediatric speech and language screening: An instrument for health professionals Ana Mendes, Ana R. Valente, Marisa Lousada O138 Anthropometric and nutritional assessment in bodybuilders Diana Sousa, Ana L. Baltazar, Mª Helena Loureiro O139 Computerized adventitious respiratory sounds in children with lower respiratory tract infections Ana Oliveira, José Aparício, Alda Marques O140 Role of computerized respiratory sounds as a marker in LRTI Alda Marques, Ana Oliveira, Joana Neves, Rodrigo Ayoub O141 Confirmatory factor analysis of the Personal Wellbeing Index in people with chronic kidney disease Luís Sousa, Cristina Marques-Vieira, Sandy Severino, Helena José O142 Phonological awareness skills in school aged children Inês Cadorio, Marisa Lousada O143 Assessment of early memories of warmth and safeness in interaction with peers: its relationship with psychopathology in adolescence Marina Cunha, Diogo Andrade, Ana Galhardo, Margarida Couto O144 The molecular effects induced by single shot irradiation on a diffuse large B cell lymphoma cell line Fernando Mendes, Cátia Domingues, Susann Schukg, Ana M. Abrantes, Ana C. Gonçalves, Tiago Sales, Ricardo Teixo, Rita Silva, Jéssica Estrela, Mafalda Laranjo, João Casalta-Lopes, Clara Rocha, Paulo C. Simões, Ana B. Sarmento-Ribeiro, Mª Filomena Botelho, Manuel S. Rosa O145 Morpho-functional characterization of cardiac chambers by Transthoracic Echocardiography, in young athletes of gymnastics competition Virgínia Fonseca, Diogo Colaço, Vanessa Neves O146 Prevalence of the antibodies of the new histo-blood system – FORS system Carlos Jesus, Camilla Hesse, Clara Rocha, Nádia Osório, Ana Valado, Armando Caseiro, António Gabriel, Lola Svensson, Fernando Mendes, Wafa A. Siba, Cristina Pereira, Jorge Tomaz O147 Assessment of the war-related perceived threat in Portuguese Colonial War Veterans Teresa Carvalho, José Pinto-Gouveia, Marina Cunha O148 Pulse transit time estimation for continuous blood pressure measurement: A comparative study Diana Duarte, Nuno V. Lopes, Rui Fonseca-Pinto O149 Blood pressure assessment during standard clinical manoeuvres: A non-invasive PPT based approach Diana Duarte, Nuno V. Lopes, Rui Fonseca-Pinto O150 Development and initial validation of the Activities and Participation Profile related to Mobility (APPM) Anabela C. Martins O151 MEASYCare-2010 Standard–A geriatric evaluation system in primary health care: Reliability and validity of the latest version in Portugal Piedade Brandão, Laura Martins, Margarida Cardoso O152 Interrater and intrarater reliability and agreement of the range of shoulder flexion in the standing upright position through photographic assessment Nuno Morais, Joana Cruz O153 Three-dimensional biofabrication techniques for tissue regeneration Nuno Alves, Paula Faria, Artur Mateus, Pedro Morouço O154 A new computer tool for biofabrication applied to tissue engineering Nuno Alves, Nelson Ferreira, Artur Mateus, Paula Faria, Pedro Morouço O155 Development and psychometric qualities of a scale to measure the functional independence of adolescents with motor impairment Isabel Malheiro, Filomena Gaspar, Luísa Barros O156 Organizational Trust in Health services: Exploratory and Confirmatory factor analysis of the Organizational Trust Inventory- Short Form (OTI-SF) Pedro Parreira, Andreia Cardoso, Lisete Mónico, Carla Carvalho, Albino Lopes, Anabela Salgueiro-Oliveira O157 Thermal symmetry: An indicator of occupational task asymmetries in physiotherapy Adérito Seixas, Valter Soares, Tiago Dias, Ricardo Vardasca, Joaquim Gabriel, Sandra Rodrigues O158 A study of ICT active monitoring adoption in stroke rehabilitation Hugo Paredes, Arsénio Reis, Sara Marinho, Vítor Filipe, João Barroso O159 Paranoia Checklist (Portuguese Version): Preliminary studies in a mixed sample of patients and healthy controls Carolina Da Motta, Célia B. Carvalho, José Pinto-Gouveia, Ermelindo Peixoto O160 Reliability and validity of the Composite Scale on Morningness: European Portuguese version, in adolescents and young adults Ana A. Gomes, Vanessa Costa, Diana Couto, Daniel R. Marques, José A. Leitão, José Tavares, Maria H. Azevedo, Carlos F. Silva O161 Evaluation scale of patient satisfaction with nursing care: Psychometric properties evaluation João Freitas, Pedro Parreira, João Marôco O162 Impact of fibromyalgia on quality of life: Comparing results from generic instruments and FIQR Miguel A. Garcia-Gordillo, Daniel Collado-Mateo, Gang Chen, Angelo Iezzi, José A. Sala, José A. Parraça, Narcis Gusi O163 Preliminary study of the adaptation and validation of the Rating Scale of Resilient Self: Resilience, self-harm and suicidal ideation in adolescents Jani Sousa, Mariana Marques, Jacinto Jardim, Anabela Pereira, Sónia Simões, Marina Cunha O164 Development of the first pressure ulcer in inpatient setting: Focus on length of stay Pedro Sardo, Jenifer Guedes, João Lindo, Paulo Machado, Elsa Melo O165 Forms of Self-Criticizing and Self-Reassuring Scale: Adaptation and early findings in a sample of Portuguese children Célia B. Carvalho, Joana Benevides, Marina Sousa, Joana Cabral, Carolina Da Motta O166 Predictive ability of the Perinatal Depression Screening and Prevention Tool – Preliminary results of the dimensional approach Ana T. Pereira, Sandra Xavier, Julieta Azevedo, Elisabete Bento, Cristiana Marques, Rosa Carvalho, Mariana Marques, António Macedo O167 Psychometric properties of the BaSIQS-Basic Scale on insomnia symptoms and quality of sleep, in adults and in the elderly Ana M. Silva, Juliana Alves, Ana A. Gomes, Daniel R. Marques, Mª Helena Azevedo, Carlos Silva O168 Enlightening the human decision in health: The skin melanocytic classification challenge Ana Mendes, Huei D. Lee, Newton Spolaôr, Jefferson T. Oliva, Wu F. Chung, Rui Fonseca-Pinto O169 Test-retest reliability household life study and health questionnaire Pomerode (SHIP-BRAZIL) Keila Bairros, Cláudia D. Silva, Clóvis A. Souza, Silvana S. Schroeder O170 Characterization of sun exposure behaviours among medical students from Nova Medical School Elsa Araújo, Helena Monteiro, Ricardo Costa, Sara S. Dias, Jorge Torgal O171 Spirituality in pregnant women Carolina G. Henriques, Luísa Santos, Elisa F. Caceiro, Sónia A. Ramalho O172 Polypharmacy in older patients with cancer Rita Oliveira, Vera Afreixo, João Santos, Priscilla Mota, Agostinho Cruz, Francisco Pimentel O173 Quality of life of caregivers of people with advanced chronic disease: Translation and validation of the quality of life in life threatening illness - family carer version (QOLLTI-C-PT) Rita Marques, Mª Anjos Dixe, Ana Querido, Patrícia Sousa O174 The psychometric properties of the brief Other as Shamer Scale for Children (OAS-C): preliminary validation studies in a sample of Portuguese children Joana Benevides, Carolina Da Motta, Marina Sousa, Suzana N. Caldeira, Célia B. Carvalho O175 Measuring emotional intelligence in health care students – Revalidation of WLEIS-P Ana Querido, Catarina Tomás, Daniel Carvalho, João Gomes, Marina Cordeiro O176 Health indicators in prenatal assistance: The impact of computerization and of under-production in basic health centres Joyce O. Costa, Frederico C. Valim, Lígia C. Ribeiro O177 Hope genogram: Assessment of resources and interaction patterns in the family of the child with cerebral palsy Zaida Charepe, Ana Querido, Mª Henriqueta Figueiredo O178 The influence of childbirth type in postpartum quality of life Priscila S. Aquino, Samila G. Ribeiro, Ana B. Pinheiro, Paula A. Lessa, Mirna F. Oliveira, Luísa S. Brito, Ítalo N. Pinto, Alessandra S. Furtado, Régia B. Castro, Caroline Q. Aquino, Eveliny S. Martins O179 Women’s beliefs about pap smear test and cervical cancer: influence of social determinants Ana B Pinheiro, Priscila S. Aquino, Lara L. Oliveira, Patrícia C. Pinheiro, Caroline R. Sousa, Vívien A. Freitas, Tatiane M. Silva, Adman S. Lima, Caroline Q. Aquino, Karizia V. Andrade, Camila A. Oliveira, Eglidia F. Vidal O180 Validity of the Portuguese version of the ASI-3: Is anxiety sensitivity a unidimensional or multidimensional construct? Ana Ganho-Ávila, Mariana Moura-Ramos, Óscar Gonçalves, Jorge Almeida O181 Lifestyles of higher education students: the influence of self-esteem and psychological well-being Armando Silva, Irma Brito, João Amado P75 Assessing the quality of life of persons with significant intellectual disability: Portuguese version of Escala de San Martín António Rodrigo, Sofia Santos, Fernando Gomes P76 Childhood obesity and breastfeeding - A systematic review Marlene C. Rosa, Silvana F. Marques P77 Cross-cultural adaptation of the Foot and Ankle Ability Measure (FAAM) for the Portuguese population Sara Luís, Luís Cavalheiro, Pedro Ferreira, Rui Gonçalves P78 Cross-cultural adaptation of the Patient-Rated Wrist Evaluation score (PRWE) for the Portuguese population Rui S. Lopes, Luís Cavalheiro, Pedro Ferreira, Rui Gonçalves P79 Cross-cultural adaptation of the Myocardial Infraction Dimensional Assessment Scale (MIDAS) for Brazilian Portuguese language Bruno H. Fiorin, Marina S. Santos, Edmar S. Oliveira, Rita L. Moreira, Elizabete A. Oliveira, Braulio L. Filho P80 The revised Portuguese version of the Three-Factor Eating Questionnaire: A confirmatory factor analysis Lara Palmeira, Teresa Garcia, José Pinto-Gouveia, Marina Cunha P81 Assessing weight-related psychological inflexibility: An exploratory factor analysis of the AAQW’s Portuguese version Sara Cardoso, Lara Palmeira, Marina Cunha; José Pinto-Gouveia P82 Validation of the Body Appreciation Scale-2 for Portuguese women Joana Marta-Simões, Ana L. Mendes, Inês A. Trindade, Sara Oliveira, Cláudia Ferreira P83 The Portuguese validation of the Dietary Intent Scale Ana L. Mendes, Joana Marta-Simões, Inês A. Trindade, Cláudia Ferreira P84 Construction and validation of the Inventory of Marital Violence (IVC) Filipe Nave P85 Portable continuous blood pressure monitor system Mariana Campos, Iris Gaudêncio, Fernando Martins, Lino Ferreira, Nuno Lopes, Rui Fonseca-Pinto P86 Construction and validation of the Scale of Perception of the Difficulties in Caring for the Elderly (SPDCE) Rogério Rodrigues, Zaida Azeredo, Corália Vicente P87 Development and validation of a comfort rating scale for the elderly hospitalized with chronic illness Joana Silva, Patrícia Sousa, Rita Marques P88 Construction and validation of the Postpartum Paternal Quality of Life Questionnaire (PP-QOL) Isabel Mendes, Rogério Rodrigues, Zaida Azeredo, Corália Vicente P89 Infrared thermal imaging: A tool for assessing diabetic foot ulcers Ricardo Vardasca, Ana R. Marques, Adérito Seixas, Rui Carvalho, Joaquim Gabriel P90 Pressure ulcers in an intensive care unit: An experience report Paulo P. Ferreira, Michelle T. Oliveira, Anderson R. Sousa, Ana S. Maia, Sebastião T. Oliveira, Pablo O. Costa, Maiza M. Silva P91 Validation of figures used in evocations: instrument to capture representations Cristina Arreguy-Sena, Nathália Alvarenga-Martins, Paulo F. Pinto, Denize C. Oliveira, Pedro D. Parreira, Antônio T. Gomes, Luciene M. Braga P92 Telephone assistance to decrease burden in informal caregivers of stroke older people: Monitoring and diagnostic evaluation Odete Araújo, Isabel Lage, José Cabrita, Laetitia Teixeira P93 Hope of informal caregivers of people with chronic and advanced disease Rita Marques, Mª Anjos Dixe, Ana Querido, Patrícia Sousa P94 Functionality and quality information from the Portuguese National Epidemiological Surveillance System Sara Silva, Eugénio Cordeiro, João Pimentel P95 Resting metabolic rate objectively measured vs. Harris and Benedict formula Vera Ferro-Lebres, Juliana A. Souza, Mariline Tavares O182 Characteristics of non-urgent patients: Cross-sectional study of an emergency department Mª Anjos Dixe, Pedro Sousa, Rui Passadouro, Teresa Peralta, Carlos Ferreira, Georgina Lourenço O183 Physical fitness and health in children of the 1st Cycle of Education João Serrano, João Petrica, Rui Paulo, Samuel Honório, Pedro Mendes O184 The impact of physical activity on sleep quality, in children Alexandra Simões, Lucinda Carvalho, Alexandre Pereira O185 What is the potential for using Information and Communication Technologies in Arterial Hypertension self-management? Sara Silva, Paulino Sousa, José M. Padilha O186 Exploring psychosocial factors associated with risk of falling in older patients undergoing haemodialysis Daniela Figueiredo, Carolina Valente, Alda Marques O187 Development of pressure ulcers on the face in patients undergoing non-invasive ventilation Patrícia Ribas, Joana Sousa, Frederico Brandão, Cesar Sousa, Matilde Martins O188 The elder hospitalized: Limiting factors of comfort Patrícia Sousa, Rita Marques O189 Physical activity and health state self-perception by Portuguese adults Francisco Mendes, Rosina Fernandes, Emília Martins, Cátia Magalhães, Patrícia Araújo O190 Satisfaction with social support in the elderly of the district of Bragança Carla Grande, Mª Augusta Mata, Juan G. Vieitez O191 Prevalence of death by traumatic brain injury and associated factors in intensive care unit of a general hospital, Brazil Bruna Bianchini, Nazare Nazario, João G. Filho, Marcia Kretzer O192 Relation between family caregivers burden and health status of elderly dependents Tânia Costa, Armando Almeida, Gabriel Baffour O193 Phenomena sensitive to nursing care in day centre Armando Almeida, Tânia Costa, Gabriel Baffour O194 Frailty: what do the elderly think? Zaida Azeredo, Carlos Laranjeira, Magda Guerra, Ana P. Barbeiro O195 The therapeutic self-care as a nursing-sensitive outcome: A correlational study Regina Ferreira O196 Phonetic-phonological acquisition for the European Portuguese from 18 months to 6 years and 12 months Sara Lopes, Liliana Nunes, Ana Mendes O197 Quality of life of patients undergoing liver transplant surgery Julian Martins, Dulcineia Schneider, Marcia Kretzer, Flávio Magajewski O198 Professional competences in health: views of older people from different European Countries Célia Soares, António Marques O199 Life satisfaction of working adults due to the number of hours of weekly exercise Marco Batista, Ruth J. Castuera, Helena Mesquita, António Faustino, Jorge Santos, Samuel Honório O200 Therapeutic itinerary of women with breast cancer in Santa Maria City/RS Betina P. Vizzotto, Leticia Frigo, Hedioneia F. Pivetta O201 The breastfeeding prevalence at 4 months: Maternal experience as a determining factor Dolores Sardo O202 The impact of the transition to parenthood in health and well-being Cristina Martins, Wilson Abreu, Mª Céu Figueiredo P96 Self-determined motivation and well-being in Portuguese active adults of both genders Marco Batista, Ruth Jimenez-Castuera, João Petrica, João Serrano, Samuel Honório, Rui Paulo, Pedro Mendes P97 The geriatric care: ways and means of comforting Patrícia Sousa, Rita Marques P98 The influence of relative age, subcutaneous adiposity and physical growth on Castelo Branco under-15 soccer players 2015 António Faustino, Paulo Silveira, João Serrano, Rui Paulo, Pedro Mendes, Samuel Honório P99 Data for the diagnostic process focused on self-care – managing medication regime: An integrative literature review Catarina Oliveira, Fernanda Bastos, Inês Cruz P100 Art therapy as mental health promotion for children Cláudia K. Rodriguez, Márcia R. Kretzer, Nazaré O. Nazário P101 Chemical characterization of fungal chitosan for industrial applications Pedro Cruz, Daniela C. Vaz, Rui B. Ruben, Francisco Avelelas, Susana Silva, Mª Jorge Campos P102 The impact of caring older people at home Maria Almeida, Liliana Gonçalves, Lígia Antunes P103 Development of the first pressure ulcer in an inpatient setting: Focus on patients’ characteristics Pedro Sardo, Jenifer Guedes, João Simões, Paulo Machado, Elsa Melo P104 Association between General Self-efficacy and Physical Activity among Adolescents Susana Cardoso, Osvaldo Santos, Carla Nunes, Isabel Loureiro O203 Characterization of the habits of online acquisition of medicinal products in Portugal Flávia Santos, Gilberto Alves O204 Waiting room – A space for health education Cláudia Soar, Teresa O. Marsi O205 Safey culture evaluation in hospitalized children Ernestina Silva, Dora Pedrosa, Andrea Leça, Daniel Silva O206 Sexual Self-awareness and Body Image Ana Galvão, Maria Gomes, Paula Fernandes, Ana Noné O207 Perception of a Portuguese population regarding the acquisition and consumption of functional foods Jaime Combadão, Cátia Ramalhete, Paulo Figueiredo, Patrícia Caeiro O208 The work process in primary health care: evaluation in municipalities of southern Brazil Karine C. Fontana, Josimari T. Lacerda, Patrícia O. Machado O209 Exploration and evaluation of potential probiotic lactic acid bacteria isolated from Amazon buffalo milk Raphaelle Borges, Flávio Barbosa, Dayse Sá O210 Road safety for children: Using children’s observation, as a passenger Germana Brunhoso, Graça Aparício, Amâncio Carvalho O211 Perception and application of quality-by-design by the Pharmaceutical industry in Portugal Ana P. Garcia, Paula O. Fernandes, Adriana Santos O212 Oral health among Portuguese children and adolescents: a public health issue Nélio Veiga, Carina Brás, Inês Carvalho, Joana Batalha, Margarida Glória, Filipa Bexiga, Inês Coelho, Odete Amaral, Carlos Pereira O213 Plant species as a medicinal resource in Igatu-Chapada Diamantina (Bahia, Brazil) Cláudia Pinho, Nilson Paraíso, Ana I. Oliveira, Cristóvão F. Lima, Alberto P. Dias O214 Characterization of cognitive and functional performance in everyday tasks: Implications for health in institutionalised older adults Pedro Silva, Mário Espada, Mário Marques, Ana Pereira O215 BMI and the perception of the importance given to sexuality in obese and overweight people Ana Mª Pereira, Mª Veiga-Branco, Filomena Pereira, Maria Ribeiro O216 Analysis and comparison of microbiological contaminations of two different composition pacifiers Vera Lima, Ana I. Oliveira, Cláudia Pinho, Graça Cruz, Rita F. Oliveira, Luísa Barreiros, Fernando Moreira O217 Experiences of couple relationships in the transition to retirement Ana Camarneiro, Mª Helena Loureiro, Margarida Silva O218 Preventive and corrective treatment of drug-induced calcium deficiency: an analysis in a community pharmacy setting Catarina Duarte, Ângelo Jesus, Agostinho Cruz O219 Profile of mood states in physically active elderly subjects: Is there a relation with health perception? Maria Mota, Sandra Novais, Paulo Nogueira, Ana Pereira, Lara Carneiro, Paulo V. João O220 (Un)Safety behaviour at work: the role of education towards a health and safety culture Teresa Maneca Lima O221 Analysis of the entrepreneurial profile of students attending higher education in Portugal: the Carland Entrepreneurship Index application Anabela Salgueiro-Oliveira, Marina Vaquinhas, Pedro Parreira, Rosa Melo, João Graveto, Amélia Castilho, José H. Gomes O222 Evaluation of welfare and quality of life of pregnant working women regarding the age of the pregnant María S. Medina, Valeriana G. Blanco O223 Psychological wellbeing protection among unemployed and temporary workers: Uncovering effective community-based interventions with a Delphi panel Osvaldo Santos, Elisa Lopes, Ana Virgolino, Alexandra Dinis, Sara Ambrósio, Inês Almeida, Tatiana Marques, Mª João Heitor O224 Chilean population norms derived from the Health-related quality of life SF-6D Miguel A. Garcia-Gordillo, Daniel Collado-Mateo, Pedro R. Olivares, José A. Parraça, José A. Sala O225 Motivation of college students toward Entrepreneurship: The influence of social and economic instability Amélia Castilho, João Graveto, Pedro Parreira, Anabela Oliveira, José H. Gomes, Rosa Melo, Marina Vaquinhas O226 Use of aromatic and medicinal plants, drugs and herbal products in Bragança city Mónia Cheio, Agostinho Cruz, Olívia R. Pereira O227 Edible flowers as new novel foods concept for health promotion Sara Pinto, Adriana Oliveira, M. Conceição Manso, Carla Sousa, Ana F. Vinha O228 The influence of leisure activities on the health and welfare of older people living in nursing homes Mª Manuela Machado, Margarida Vieira O229 Risk of falling, fear of falling and functionality in community-dwelling older adults Beatriz Fernandes, Teresa Tomás, Diogo Quirino O230 Musculoskeletal pain and postural habits in children and teenage students Gustavo Desouzart, Rui Matos, Magali Bordini, Pedro Mouroço O231 What's different in Southern Europe? The question of citizens’ participation in health systems Ana R. Matos, Mauro Serapioni O232 Occupational stress in Portuguese police officers Teresa Guimarães, Virgínia Fonseca, André Costa, João Ribeiro, João Lobato O233 Is occupational therapy culturally relevant to promote mental health in Burkina Faso? Inmaculada Z. Martin, Anita Björklund P105 Pay-for-performance satisfaction and quality in primary care Aida I. Tavares, Pedro Ferreira, Rui Passadouro P106 Economic development through life expectancy lenses Sónia Morgado P107 What is the effectiveness of exercise on smoking cessation to prevent clinical complications of smoking? Nuno Tavares, João Valente, Anabela C. Martins P108 A systematic review of the effects of yoga on mental health Patrícia Araújo, Rosina Fernandes, Francisco Mendes, Cátia Magalhães, Emília Martins P109 Healthy lifestyle: comparison between higher education students that lived until adult age in rural and urban environment Pedro Mendes, Rui Paulo, António Faustino, Helena Mesquita, Samuel Honório, Marco Batista P110 Evaluation of the Mobile Emergency Care Service (SAMU) in Brazil Josimari T. Lacerda, Angela B. Ortiga, Mª Cristina Calvo, Sônia Natal P111 Bioactive compounds - antioxidant activity of tropical fruits Marta Pereira P112 Use of non-pharmacological methods to relieve pain in labour Manuela Ferreira, Ana R. Prata, Paula Nelas, João Duarte P113 Mechanical safety of pacifiers sold in Portuguese pharmacies and childcare stores Juliana Carneiro, Ana I. Oliveira, Cláudia Pinho, Cristina Couto, Rita F. Oliveira, Fernando Moreira P114 The importance of prenatal consultation: Information to pregnant women given on a unit of primary care Ana S. Maia, Michelle T. Oliveira, Anderson R. Sousa, Paulo P. Ferreira, Géssica M. Souza, Lívia F. Almada, Milena A. Conceição, Eujcely C. Santiago P115 Influence of different backpack loading conditions on neck and lumbar muscles activity of elementary school children Sandra Rodrigues, Gabriela Domingues, Irina Ferreira, Luís Faria, Adérito Seixas P116 Efficacy and safety of dry extract Hedera helix in the treatment of productive cough Ana R. Costa, Ângelo Jesus, Américo Cardoso, Alexandra Meireles, Armanda Colaço, Agostinho Cruz P117 A portrait of the evaluation processes of education groups in primary health care Viviane L. Vieira, Kellem R. Vincha, Ana Mª Cervato-Mancuso P118 Benefits of vitamins C and E in sensorineural hearing loss: a review Melissa Faria, Cláudia Reis P119 BODY SNAPSHOT – a web-integrated anthropometric evaluation system Marco P. Cova, Rita T. Ascenso, Henrique A. Almeida, Eunice G. Oliveira P120 Anthropometric evaluation and variation during pregnancy Miguel Santana, Rafael Pereira, Eunice G. Oliveira, Henrique A. Almeida, Rita T. Ascenso P121 Knowledge of college students on the amendments of their eating habits and physical activity index in the transition to higher education Rita Jesus, Rodrigo Tapadas, Carolina Tim-Tim, Catarina Cezanne, Matilde Lagoa, Sara S. Dias, Jorge Torgal P122 Muscular activity of a rally race car driver João Lopes, Henrique Almeida, Sandra Amado, Luís Carrão O234 Literacy and results in health Madalena Cunha, Luís Saboga-Nunes, Carlos Albuquerque, Olivério Ribeiro O235 Literacy promotion and empowerment of type 2 diabetics elderly in four family health units of the group of health centers of Dão Lafões Suzete Oliveira, Mª Carminda Morais O236 Mediterranean diet, health and life quality among Portuguese children Emília Martins, Francisco Mendes, Rosina Fernandes, Cátia Magalhães, Patrícia Araújo O237 Health literacy, from data to action - translation, validation and application of the European Health Literacy Survey in Portugal (HLS-EU-PT) Ana R. Pedro, Odete Amaral, Ana Escoval O238 Oral health literacy evaluation in a Portuguese military population Victor Assunção, Henrique Luís, Luís Luís O239 Preferences to Internet-based cognitive behavioural therapy – do attachment orientations matter? Jennifer Apolinário-Hagen, Viktor Vehreschild O240 A comparative transnational study in health literacy between Austria and Portugal Ulrike Fotschl, Gerald Lirk, Anabela C. Martins, Isabel Andrade, Fernando Mendes O241 Health literacy and social behaviours: relationship with sexually transmitted diseases? Verónica Mendonça, Sandra Antunes, Isabel Andrade, Nádia Osório, Ana Valado, Armando Caseiro, António Gabriel, Anabela C. Martins, Fernando Mendes O242 Parenting styles and attachment to parents: what relationships? Paula A. Silva, Lisete M. Mónico, Pedro M. Parreira, Carla Carvalho O243 Work-life balance in health professionals and professors: comparative study of workers with shift work and fixed schedule Carla Carvalho, Pedro M. Parreira, Lisete M. Mónico, Joana Ruivo O244 Technology literacy in self-management of diabetes Vânia Silva, Paulino Sousa, José M. Padilha O245 Satisfaction with therapeutic education and its relationship with clinical variables in children with type 1 diabetes Vera Ferraz, Graça Aparício, João Duarte O246 Nutrition-related knowledge in middle-age and older patients with type 2 diabetes Carlos Vasconcelos, António Almeida, Joel Neves, Telma Correia, Helena Amorim, Romeu Mendes O247 Validating the HLS-EU-(PT) questionnaire to measure health literacy in adolescents (CrAdLiSa project: HLS-EU-PT) Luís Saboga-Nunes, Madalena Cunha, Carlos Albuquerque O248 Health education in people with coronary heart disease: Experience of the cardiology department of a hospital on the outskirts of Lisbon Elsa S. Pereira, Leonino S. Santos, Ana S. Reis, Helena R. Silva, João Rombo, Jorge C. Fernandes, Patrícia Fernandes O249 Information and training needs of informal caregivers of individuals with stroke sequelae: a qualitative survey Jaime Ribeiro, Catarina Mangas, Ana Freire O250 Prevention of psychoactive substances consumption in students from 6th grade of Albergaria-a-Velha´s School Group Sara Silva, Irene Francisco, Ana Oliveira O251 Promoting healthy sexuality: shared responsibility for family, youth and educators Helena Catarino, Mª Anjos Dixe, Mª Clarisse Louro O252 Sexual risk behaviour in adolescents and young people Saudade Lopes, Anjos Dixe O253 Knowledge of school staff on type 1 diabetes Mª Anjos Dixe, Eva Menino, Helena Catarino, Fátima Soares, Ana P. Oliveira, Sara Gordo, Teresa Kraus O254 Sexual health in adolescents: the impact of information search in literacy Catarina Tomás, Paulo Queirós, Teresa Rodrigues P123 Improving basic life support skills in adolescents through a training programme Pedro Sousa, João G. Frade, Catarina Lobão P124 Difficulties in sexual education reported by basic education teachers in the city of Foz do Iguaçu - Brazil Cynthia B. Moura, Laysa C. Dreyer, Vanize Meneghetti, Priscila P. Cabral P125 Breast cancer survivors: subjects and resources for information. A qualitative systematic review Francisca Pinto, Paulino Sousa, Mª Raquel Esteves P126 Relationship between health literacy and prevalence of STI in Biomedical Laboratory Science students Sofia Galvão, Ite Tytgat, Isabel Andrade, Nádia Osório, Ana Valado, Armando Caseiro, António Gabriel, Anabela C. Martins, Fernando Mendes P127 Health literacy, risk behaviours and sexually transmitted diseases among blood donors Mónica Casas-Novas, Helena Bernardo, Isabel Andrade, Gracinda Sousa, Ana P. Sousa, Clara Rocha, Pedro Belo, Nádia Osório, Ana Valado, Armando Caseiro, António Gabriel, Anabela C. Martins, Fernando Mendes P128 Promoting literacy in pregnancy health-care Fátima Martins, Montserrat Pulido-Fuentes P129 The lifestyles of the operating assistants of education Isabel Barroso, Gil Cabral, M. João Monteiro, Conceição Rainho P130 Experiences of service-learning health and the literary art: reflections about the health education Alessandro Prado, Yara M. Carvalho P131 Life long swimming – a European Erasmus + project Maria Campos, Liliana Moreira, José Ferreira, Ana Teixeira, Luís Rama AD - Health Sciences Research Unit: Nursing, Collegue of College of Health Technology of Coimbra, Coimbra, Portugal Sisters Hospitallers of the Sacred Heart of Jesus, Casa de Saúde Rainha Santa Isabel, Coimbra, Portugal Research Unit for Sport and Physical Activity, Faculty of Sport Sciences and Physical Education, University of Coimbra, Coimbra, Portugal Complementary Sciences- INESCC, Coimbra, Portugal CUF Hospitals, Lisbon, Portugal Breast Unit, Champalimaud Clinical Center, Lisbon, Portugal Swiss Centre for Medical Simulation & Swiss Association of Simulation in Healthcare, 4031 Basel, Switzerland Basel University Hospital, 4056 Basel, Switzerland HELPO Association, 2750-318 Cascais, Portugal Centro de Linguística, Universidade de Lisboa, Lisboa, Portugal Centro Superior de Estudios Universitarios La Salle, Madrid, Spain Universidade da Madeira, 9000-082 Funchal, Portugal Serviço de Saúde da Região Autónoma da Madeira, E.P.E., 9004-514 Funchal, Portugal Escola Superior de Enfermagem de Lisboa, 1700-063 Lisboa, Portugal Instituto Superior Miguel Torga, Coimbra, 3000-132 Coimbra Portugal Centro de Investigação do Núcleo de Estudos e Intervenção Cognitivo Comportamental, Universidade de Coimbra, Coimbra, 3001-802 Portugal Escola Superior de Saúde de Leiria & Unidade de Investigação em Saúde, Instituto Politécnico de Leiria, 2411-901 Leiria, Portugal National School of Public Health & Centro de Investigação em Saúde Pública, Universidade Nova de Lisboa, 1600-560 Lisboa, Portugal Agrarian Superior School, Polytechnic Institute of Viseu, 3500-606 Viseu, Portugal Laboratory of Microbiology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal Unit for Multidisciplinary Biomedical Research, Institute of Biomedical Sciences Abel Salazar, University of Porto, 4050-313 Porto, Portugal Agrupamento de Centros de Saúde (ACES) Baixo Mondego, 3080-199 Figueira da Foz, Portugal Universidade de Trás-os-Montes e Alto Douro, Vila Real, 5001-801 Portugal Centro de Salud La Paz, Badajoz, 06011 Badajoz España Centro de Salud San Fernando, Badajoz, 06006 Badajoz España Complejo Hospitalario Universitario de Badajoz, Badajoz, 06080 Badajoz España Hospital Don Benito-Villanueva, Don Benito, 06400 Badajoz España Centro de Salud Villanueva Norte, Villanueva de la Serena, 06700 Badajoz España Centro de Salud Gevora, 06180 Gévora, Badajoz España Universidade Fernando Pessoa, Porto, 4249-004 Portugal Centro de Salud La Paz, Badajoz, 06011 España Universidad de Extremadura, Badajoz, 06071 Badajoz España Faculty of Psychology and Education Sciences, University of Coimbra, Coimbra, 3001-802 Coimbra Portugal Universidade Federal de Viçosa, Viçosa, Minas Gerais 36570-900 Brasil Escola Superior de Enfermagem de Coimbra, 3046-851 Coimbra, Portugal Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais 36036-330 Brasil Centro Hospitalar e Universitário de Coimbra, 3000-075 Coimbra, Portugal School of Health Sciences, University of Aveiro, 3810-193 Aveiro, Portugal Universidade Fernando Pessoa, 4249-004 Porto, Portugal Escola Superior de Saúde Dr. Lopes Dias, Instituto Politécnico de Castelo Branco, 6000-767 Castelo Branco, Portugal Cabildo de Lanzarote, 35500 Arrecife, Lanzarote, Las Palmas España Servicio Canario de la Salud, 35500 Arrecife, Lanzarote, Las Palmas España Universidad de Las Palmas de Gran Canaria, 35001 Las Palmas de Gran Canaria, Las Palmas España Escola Superior de Saúde, Instituto Politécnico de Bragança, 5300-121 Bragança, Portugal Escola Superior de Saúde de Santarém, Santarém, 2005-075 Portugal Escola Superior de Enfermagem de Coimbra, Coimbra, 3046-851 Portugal Escola Superior de Enfermagem de Lisboa, Lisboa, 1700-063 Portugal Hospital Distrital de Santarém, EPE, Santarém, 2005-177 Portugal Universidade de Coimbra, 3004-504 Coimbra, Portugal Federal University of Rio Grande do Sul, Porto Alegre Rio Grande do Sul, 90050-170 Brasil Universidade Federal de Santa Catarina, Florianópolis, 88040-900 Brasil Instituto Superior de Serviço Social do Porto, 44600-362 Sra. da Hora, Portugal Escola Superior de Tecnologia da Saúde de Coimbra, São Martinho do Bispo, 3046-854 Coimbra, Portugal Escola Superior de Saúde, Instituto Politécnico de Viseu, 3504-510 Viseu, Portugal Universidade Federal de Alagoas, Maceió, Alagoas, 57072-900 Brasil Faculdade de Ciências do Desporto e Educação Física, Universidade de Coimbra, 3040-248 Coimbra, Portugal Faculty of Psychology and Education Sciences, University of Coimbra, Coimbra, 3000-115 Portugal Escola Superior da Saúde da Cruz Vermelha Portuguesa, Lisboa, 1300-125 Portugal Universidade de Santa Cruz do Sul, Santa Cruz do Sul, Rio Grande do Sul 96815-900 Brasil Instituto Politécnico de Portalegre, 7301-901 Portalegre, Portugal Instituto Politécnico de Bragança, Bragança, 5300-121 Portugal Universidade do Sul de Santa Catarina, Palhoça, Santa Catarina 88137-270 Brasil Secretaria Municipal de Saúde de Palhoça, Palhoça, Santa Catarina 88132-149 Brasil Cabildo de Lanzarote, 35500 Lanzarote, Las Palmas España Universidade de Aveiro, 3810-193 Aveiro, Portugal Escola Superior de Saúde Dr. Lopes Dias, Castelo Branco, 6000-767 Portugal Centro de estudos em educação, tecnologias e saúde, Instituto Politécnico de Viseu, 3504-510 Viseu, Portugal Casa de Saúde de São Mateus, Viseu, 3500-106 Portugal Universidade Católica Portuguesa, Viseu, 3504-505 Portugal Escola Nacional de Saúde Pública, Lisboa, 1600-560 Portugal Research Centre Sports Sciences, Health Sciences and Human Development, University of Trás-os-Montes e Alto Douro, Vila Real, 5001-801 Portugal Polytechnic Institute of Viseu, Viseu, 3504-510 Portugal Unidade de Saúde Pública do ACES Douro I—Marão e Douro Norte, Administração Regional de Saúde do Norte, IP, 5000-524 Vila Real, Portugal Núcleo de Investigação e Intervenção no Idoso, Departamento de Tecnologias de Diagnóstico e Terapêutica, Escola Superior de Saúde, Instituto Politécnico de Bragança, Bragança, 5300-253 Portugal Centro de Investigação de Montanha, Escola Superior Agrária, Instituto Politécnico de Bragança, 5300-253 Bragança, Portugal Escola Superior de Saúde, Instituto Politécnico de Bragança, 5300-253 Bragança, Portugal Programa de Prevenção e Controlo de Infeções e de Resistência aos Antimicrobianos, Unidade Local de Saúde do Nordeste, Bragança, 5301-852 Portugal Departamento de Urgência e Emergência Unidade, Unidade Local de Saúde do Nordeste, Bragança, 5301-852 Portugal Departamento de Enfermagem, Escola Superior de Saúde, Instituto Politécnico de Bragança, 5300-121 Bragança, Portugal Centro de Investigação em Desporto, Saúde e Desenvolvimento Humano, Departamento de Enfermagem, Escola Superior de Saúde, Instituto Politécnico de Bragança, 5300-121 Bragança, Portugal Health Superior School of Alto Ave, 4830-345 Póvoa de Lanhoso, Portugal Unidade de Investigação e Formação sobre Adultos e Idosos, Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, 4050-313 Porto, Portugal Center for Health Technology and Services Research, Faculdade de Medicina, Universidade do Porto, 4200-450 Porto, Portugal Escola Superior de Enfermagem, Universidade do Minho, Braga, 4710-057 Portugal Faculty of Medicine, University of Coimbra, 3000-354 Coimbra, Portugal Centro de responsabilidade integrado, Serviço Psiquiatria, Centro Hospitalar e Universitário de Coimbra, 3000-354 Coimbra, Portugal University of Trás-os-Montes e Alto Douro, Vila Real, 5001-801 Portugal Unidade de Saúde Pública, ACES Douro I, Marão e Douro Norte, Administração Regional de Saúde do Norte, 5000-524 Vila Real, Portugal Faculdade Nobre, Feira de Santana, Bahia 44001-008 Brasil Secretaria de Saúde do Estado da Bahia, Salvador, Bahia 41745-900 Brasil Hospital Estadual da Criança, Vila Valqueire, Rio de Janeiro Brasil Escola Superior de Tecnologia da Saúde, Instituto Politécnico do Porto, 4400-330 Vila Nova de Gaia, Portugal Centro Hospitalar de São João, EPE, Porto, 4200-319 Porto Portugal Unidade Local de Saúde de Matosinhos, EPE, 4454 509 Senhora da Hora, Portugal College of Health Technology, Polytechnic Institute of Coimbra, São Martinho do Bispo, 3046-854 Coimbra, Portugal Escola Superior de Saúde de Leiria, Instituto Politécnico de Leiria, 2411-901 Leiria, Portugal School of Health Sciences, Polytechnic institute of Leiria, 2411-901 Leiria, Portugal Unidade de Investigação Inclusão e Acessibilidade em Acção “iACT” e Escola Superior Educação e Ciências Sociais, Instituto Politécnico de Leiria, 2411-901 Leiria, Portugal Unidade de Investigação em Saúde, Escola Superior de Saúde de Leiria eCADR& Centro de Investigação Didática e Tecnologia na Formação de Formadores, Universidade de Aveiro, 3810-193 Aveiro, Portugal Instituto Politécnico de Leiria, 2411-901 Leiria, Portugal Universidade da Beira Interior, Covilhã, 6201-001 Portugal Unidade de Saúde Pública, Agrupamento de Centros de Saúde Cova da Beira, 6200-251 Covilhã, Portugal Centre of Studies on Geography and Spatial Planning, University of Coimbra, 3000-043 Coimbra, Portugal Research Centre for Geography and Regional Planning, Universidade Nova de Lisboa, 1069-061 Lisboa, Portugal Biomedical Sciences Department, Paulista University, São Paulo, 04026-002 Brazil Pharmacy Department, Paulista University, São Paulo, 04026-002 Brazil Molecular Laboratory of Diagnosis, ABC Medical School, Santo André, São Paulo 09080-650 Brazil Biomedical Science Department, College of Health Technology of Coimbra, Polytechnic Institute of Coimbra, São Martinho do Bispo, 3046-854 Coimbra, Portugal Hospital Sousa Martins, 6300-858 Guarda, Portugal Instituto de Medicina Preventiva e Saúde Pública, Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisboa, Portugal Instituto de Saúde Ambiental, Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisboa, Portugal Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisboa, Portugal Oslo and Akershus University College of Applied Sciences, 0167 Oslo, Norway Newcastle University Institute for Ageing, Newcastle upon Tyne, NE4 5PL United Kingdom Hospital de Santo André, Centro Hospitalar de Leiria, 2410-197 Leiria, Portugal Secção Autónoma das Ciências da Saúde, Universidade de Aveiro, 3810-193 Aveiro, Portugal Faculdade de Medicina da Universidade do Porto, 4200-450 Porto, Portugal Escola Superior de Educação de Viseu, 3504-501 Viseu, Portugal Research in Education and Community Intervention, Escola Superior de Saúde Jean Piaget, Silves, 8300-025 Portugal Escola Superior de Saúde Jean Piaget, Silves, 8300-025 Portugal Cognitive and Behavioural Centre for Research and Intervention, Faculty of Psychology and Education Sciences, University of Coimbra, 3000-115 Coimbra, Portugal Centro de Investigação do Núcleo de Estudos e Intervenção Cognitivo-Comportamental, Faculdade de Psicologia e Ciências da Educação, Universidade de Coimbra, 3001-802 Coimbra, Portugal Instituto Superior Miguel Torga, Coimbra, 3000-132 Portugal Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul 90050-170 Brasil Municipality of Nordeste, 9630 Nordeste, Azores Portugal University of Brasilia, Brasília, Distrito Federal 70910-900 Brasil Universidad de Extremadura, Badajoz, 06071 España Chrononutrition Laboratory, Department of Physiology, Faculty of Science, University of Extremadura, Badajoz, 06071 España Department of Anestesiology, Complejo Hospitalario Universitario de Badajoz, 06080 Badajoz, España Aragon Institute for Health Research, Zaragoza, 50009 España ABC Medical School, Santo André, São Paulo 09210-180 Brazil Department of Complementary Sciences, College of Health Technology of Coimbra, Polytechnic Institute of Coimbra, São Martinho do Bispo, 3046-854 Coimbra, Portugal Federal University of São Paulo, Diadema campus, Diadema, São Paulo 09913-030 Brazil Centro Hospitalar Cova da Beira, Covilhã, 6200-251 Portugal Departamento de Ciências da Saúde, Universidade Católica Portuguesa, Viseu, 3504-505 Portugal Centro de Investigação Interdisciplinar em Saúde, Universidade Católica Portuguesa, 3504-505 Viseu, Portugal Unidade de Saúde Familiar Grão Vasco, Viseu, 3500-177 Portugal School of Health Sciences, Polytechnic Institute of Guarda, 6301-559 Guarda, Portugal Research Unit for Inland Development, Polytechnic Institute of Guarda, 6301-559 Guarda, Portugal Centro de Ciências da Saúde, Departamento de Saúde Pública, Universidade Federal de Santa Catarina, Florianópolis, Santa Catarina 88040-900 Brasil College of Health Technology, Polytechnic Institute of Coimbra, 340-162 Coimbra, Portugal Oporto Portuguese Institute of Oncology FG, EPE, 4200-072 Porto, Portugal Porto Nursing School, 4200-072 Porto, Portugal Oporto Central Hospital, 4099-001 Porto, Portugal Escola Superior Escola Superior de Enfermagem do Porto, 4200-072 Porto, Portugal Centro Hospitalar do Porto, 4099-001 Porto, Portugal Instituto de Ciências da Saúde, Universidade Católica Portuguesa, 1649-023 Lisboa, Portugal Escola Superior de Enfermagem de S. João de Deus, Universidade de Évora, 7004-516 Évora, Portugal Health Research Unit & School of Health Sciences, Polytechnic institute of Leiria, 2411-901 Leiria, Portugal Escola Superior de Enfermagem do Porto, Porto, 4200-072 Portugal Faculdade de Economia, Universidade de Coimbra, 3004-512 Coimbra, Portugal Centro Hospitalar de Trás-os-Montes e Alto Douro, Vila Real, 5000-508 Portugal Escola Superior de Saúde, Instituto Politécnico de Viana do Castelo, 4900-347 Viana do Castelo, Portugal Centro de Estudos e Investigação em Saúde, Universidade de Coimbra, 3004-512 Coimbra, Portugal Escola Superior de Tecnologia da Saúde do Porto, Instituto Politécnico do Porto, Vila Nova de Gaia, 4400-330 Portugal Research in Education and Community Intervention, Escola Superior de Saúde Jean Piaget, 4405-678 Gulpilhares, Vila Nova de Gaia Portugal Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, 4050-313 Porto, Portugal Escola Superior de Saúde, Instituto Politécnico de Santarém, Santarém, 2005-075 Portugal Escola Superior de Enfermagem S. João de Deus, Universidade de Évora, 7000-811 Évora, Portugal Faculdade de Psicologia e Ciências da Educação, Universidade de Coimbra, 3001-802 Coimbra, Portugal Instituto Politécnico de Viana do Castelo, 4900-347 Viana do Castelo, Portugal Escola Superior de Saúde, Instituto Politécnico de Santarém, 2005-075 Santarém, Portugal Unidade de Investigação do Instituto Politécnico de Santarém, 2001-904 Santarém, Portugal Unidade de Monitorização de Indicadores em Saúde, Instituto Politécnico de Santarém, 2005-075 Santarém, Portugal Life Quality Research Centre, Instituto Politécnico de Santarém, 2001-904 Santarém, Portugal Hospital Prof. Doutor Fernando Fonseca E.P.E., Amadora, 2720-276 Portugal Instituto Politécnico de Bragança, Bragança, 5300-121 Bragança Portugal Universidad de León, 24004 León, España Instituto de Ciências da Saúde, Universidade Católica Portuguesa, Lisboa, 1649-023 Portugal Instituto Universitário de Ciências Psicológicas, Sociais e da Vida, 1149-041 Lisboa, Portugal Escola Superior de Enfermagem da Cruz Vermelha Portuguesa de Oliveira de Azeméis,, 3720-126 Oliveira de Azeméis, Portugal Oulu University of Applied Sciences, 90250 Oulu, Finlândia Unidade de Saúde Familiar - Espaço Saúde, Porto, 4100-503 Portugal Escola Superior de Enfermagem da Cruz Vermelha Portuguesa, 3720-126 Oliveira de Azeméis, Portugal Administração Regional de Saúde de Lisboa e Vale do Tejo, 1749-096 Lisboa, Portugal Departamento de Saúde Pública & Centro de Estudos de Doenças Crónicas, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, 1169-056 Lisboa, Portugal Faculdade de Medicina, Universidade José do Rosario Vellano, Divinópolis, Minas Gerais 35502-634 Brasil Pontifícia Universidade Católica de Campinas, Campinas, São Paulo 13086-900 Brasil Secção Autónoma das Ciências da Saúde, Universidade de Aveiro, Aveiro, 3810-193 Portugal Escola Superior de Enfermagem do Porto, 4200-072 Porto, Portugal Universidade de São Paulo, 05403-000 São Paulo, Brasil Universidade Católica Portuguesa, Lisboa, 1649-023 Portugal Escola Superior de Enfermagem da Cruz Vermelha Portuguesa de Oliveira de Azeméis, 3720-126 Oliveira de Azeméis, Portugal Academia de Teatro, 4465-095 S. Mamede de Infesta, Portugal Escola Superior de Tecnologia da Saúde de Lisboa, 1990-096 Lisboa, Portugal Unidade de Investigação em Saúde, Escola Superior de Saúde de Leiria, 2411-901 Leiria, Portugal Hospital Santa Maria Maior de Barcelos, 4754-909 Barcelos, Portugal Centro de Estudos e Investigação em Saúde, Faculdade de Economia, Universidade de Coimbra, 3004-512 Coimbra, Portugal Universidade Católica Portuguesa/Porto, 4202-401 Porto, Portugal Instituto de Medicina Molecular, Universidade de Lisboa, 1649-028 Lisboa, Portugal Faculdade de Motricidade Humana, Universidade de Lisboa, Cruz quebrada, 1499-002 Lisboa Portugal Faculdade de Medicina, Universidade de Porto, 4200-319 Porto, Portugal Escola Superior de Tecnologias de Saúde, Instituto Politécnico de Lisboa, 1990-096 Lisboa, Portugal Escola Superior de Saúde, Universidade Atlântica, 2745-615 Barcarena, Portugal Instituto de Telecomunicações, Lisboa, 1049-001 Portugal Universidade Federal de Santa Catarina, Florianópolis, Santa Catarina 88040-900 Brasil Farmácia Outeiro do Linho, 4440-762 Valongo, Portugal Hospital Militar Regional n.°1, Porto, 4150-113 Portugal Universidade Católica Portuguesa, Porto, 4202-401 Portugal Administração Regional de Saúde do Norte, Porto, 4000-447 Portugal Centro Hospitalar De São João, E.P.E., Porto, 4200-319 Portugal Escola Superior de Saúde, Instituto Politécnico de Setúbal, 2910-761 Setúbal, Portugal Ordem dos Enfermeiros da zona Centro, Coimbra, 3000-076 Portugal Research Centre in Physical Activity, Health and Leisure, Faculty of Sports, University of Porto, 4200-450 Porto, Portugal Lab 3R – Respiratory Research and Rehabilitation Laboratory, School of Health Sciences, University of Aveiro, 3810-193 Aveiro, Portugal Unidade de Surdos, Escola de Referência para a Educação Bilingue, 3830-195 Ílhavo, Portugal Center for Research and Development in Mathematics and Applications, University of Aveiro, 3810-193 Aveiro, Portugal Department of Mathematics, University of Aveiro, 3810-193 Aveiro, Portugal School of Health Care, Polytechnic Institute of Setúbal, 2910-761 Setúbal, Portugal Centro de Linguística da Universidade de Lisboa, Faculdade de Letras, Universidade de Lisboa, 1600-214 Lisboa, Portugal Center for Health Technology and Services Research, School of Health Sciences, University of Aveiro, Aveiro, 3810-193 Portugal Unidade de Investigação em Ciências da Saúde: Enfermagem, Escola Superior de Enfermagem de Coimbra, 3046-851 Coimbra, Portugal School of Health Sciences, University of Aveiro, Aveiro, 3810-193 Aveiro, Portugal Peroneo Centro Terapêutico Lda, Amieiro, Montemor-o-velho, 3140-021 Arazede Portugal Institute for Research in Biomedicine, University of Aveiro, Aveiro, 3810-292 Portugal Department of Physiotherapy, North Polytechnic Institute of Health, Gandra, 4585-116 Portugal Center for Health Technology and Services Research, University of Aveiro, Aveiro, 3810-193 Portugal Irmandade da Misericórdia de Albergaria-a-Velha, 3850-069 Albergaria-a-Velha, Portugal Gabinete de Apoio Psicológico, Instituto Superior Miguel Torga, Coimbra, 3000-132 Portugal Rehabilitation Science Institute and Department of Physical Therapy, University of Toronto, Toronto, Ontario M5S 1A1 Canada Unidade de Investigação & Desenvolvimento em Enfermagem, Escola Superior de Enfermagem de Lisboa, Lisboa, 1700-063 Portugal Centro de Tratamento Internacional VillaRamadas, 2460-355 Cela, Alcobaça, Portugal Faculdade de Economia, Universidade do Porto, 4200-464 Porto, Portugal Complejo Hospitalario Universitario de Badajoz, Badajoz, 06080 España Centro de Salud San Fernando, Badajoz, 06006 España Faculdade de Psicologia, Universidade de Lisboa, 1649-013 Lisboa, Portugal Centro de Investigação do Desporto e da Atividade Física, Faculdade de Ciências do Desporto e Educação Física, 3040-156 Coimbra, Portugal Fundação Capes, Ministério da Educação, 70.040-020 Brasília, Distrito Federal Brasil Faculty of Medicine, University of Porto, Porto, 4200-450 Portugal School of Education and Social Sciences, Polytechnic Institute of Leiria, Leiria, 2411-901 Portugal Life Quality Research Centre – IPLeiria Branch, Polytechnic Institute of Leiria, Leiria, 2411-901 Portugal Universidad de Las Palmas de Gran Canaria, 35001 Las Palmas de Gran Canaria, España Unidade de Cuidados na Comunidade da Ponte da Barca, 4980-620 Ponte da Barca, Portugal Escola Superior de Educação, Instituto Politécnico de Castelo Branco, 6000-767 Castelo Branco, Portugal Centro de Estudos em Educação, Tecnologias e Saúde, Escola Superior de Saúde, Instituto Politécnico de Viseu, 3504-510 Viseu, Portugal Studio Osteopatico Franchi, 6512 Giubiasco, Switzerland Faculty of Human Kinetics, University of Lisbon, 1649-028 Lisboa, Portugal Escola Superior de Tecnologia da Saúde de Lisboa, Instituto Politécnico de Lisboa, 1549-020 Lisboa, Portugal Escola Superior Desporto De Rio Maior, Instituto Politécnico de Santarém, 2040-413 Rio Maior, Portugal Department of Legal Medicine and Forensic Sciences, Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal Portugal & Pharmaceutical Services, Centro Hospitalar de Vila Nova de Gaia/Espinho, EPE, Vila Nova de Gaia, 4400-129 Portugal Núcleo de Investigação e Intervenção em Farmácia, Centro de Investigação em Saúde e Ambiente, Instituto Politécnico do Porto, Vila Nova de Gaia, 4400-330 Portugal Secção Autónoma de Ciências da Saúde, Universidade de Aveiro, 3810-193 Aveiro, Portugal Hospital SAMS – Serviços de Assistência Médico-social do Sindicato dos Bancários, 1849-017 Lisboa, Portugal North Tyneside General Hospital, Tyne and Wear, NE29 8NH Newcastle UK Life Quality Research Centre, Instituto Politécnico de Castelo Branco, 6000-767 Castelo Branco, Portugal School of Education and Social Sciences, Polytechnic Institute of Leiria, 2411-901 Leiria, Portugal Unidade de Saúde Pública, ACES Pinhal Litoral, ARS Centro, 3100-462 Pombal, Portugal Health Research Unit, School of Health Sciences, Polytechnic institute of Leiria, 2411-901 Leiria, Portugal Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, 1649-035 Lisboa, Portugal Associação Portuguesa de Pais e Amigos do Cidadão Deficiente Mental, 6200-050 Covilhã, Portugal Unidade de Cuidados na Comunidade, Centro de Saúde de Anadia, 3780-780 Anadia, Portugal Fisiatris - Recuperação Física, Lda, Sacavém, 2685-010 Portugal Research Centre of Sports Sciences, Health Sciences and Human Development, Universidade da Beira Interior, Covilhã, 6201-001 Covilhã Portugal Escola Superior de Desporto de Rio Maior, Instituto Politécnico de Santarém, 2040-413 Rio Maior, Portugal Research, Education and Community Intervention, Instituto Piaget, 3515-776 Galifonge, Viseu Portugal Centro Interdisciplinar de Estudo da Performance Humana, Faculdade de Motricidade Humana, Universidade Nova de Lisboa, 1499-002 Cruz Quebrada, Portugal Centro de Investigação e Qualidade de Vida, Instituto Politécnico de Santarém, 2040-413 Rio Maior, Portugal Research Centre in Sports Sciences, Health and Human Development, University of Trás-os-Montes and Alto Douro, Vila Real, 5001-801 Portugal Lar Cantinho dos Avós - Santa Casa da Misericórdia de Melgaço, 4960-570 Melgaço, Portugal Unidade Local de Saúde do Alto Minho, EPE, 4904-858 Viana do Castelo, Portugal Fundação de amparo à pesquisa e inovação do Espírito Santo, Vitória, Esprito Santo 29066-380 Brasil Universidade Estadual de Feira de Santana, Feira de Santana, Bahia 44036-900 Brasil Centro de Investigação em Saúde e Ambiente, Instituto Politécnico do Porto, Vila Nova de Gaia, 4400-330 Portugal Hospital de Santo Antonio, Centro Hospitalar do Porto, EPE, 4099-001 Porto, Portugal Pharmaceutical Services, Centro Hospitalar de Vila Nova de Gaia/Espinho, EPE, Vila Nova de Gaia, 4400-129 Portugal Centro Hospitalar de São João, EPE, Porto, 4200-319 Portugal Escola Superior de Saúde, Instituto Politécnico de Bragança, Bragança, 5300-253 Portugal Unidade Local de Saúde da Guarda, E.P.E, 6300-858 Guarda, Portugal Clínica Espregueira-Mendes Sports Centre, FIFA Medical Centre of Excellence, 4350-415 Porto, Portugal Faculdade de Desporto, Universidade do Porto, 4200-450 Porto, Portugal Centro de Ação Social do Concelho de Ílhavo, 3830-201 Ílhavo, Portugal Zelar, Serviços de Apoio Domiciliário, 3810-232 Aveiro, Portugal Walk’In Clinics, Esgueira, 3800-042 Aveiro, Portugal São João de Deus Clinic, 1749-098 Lisboa, Portugal Arrabida Hospital, 4400-346 Vila Nova de Gaia, Portugal Yasmin Residence, 2500-064 Caldas da Rainha, Portugal Faro unit, Algarve Hospital, 8000-386 Faro, Portugal School of Health Sciences, University of Aveiro, Aveiro, 3810-193 Portugal School of Health Sciences, Polytechnic institute of Leiria, Leiria, 2411-901 Portugal Health Research Unit, Polytechnic institute of Leiria, Leiria, 2411-901 Portugal Instituto de Ciências Sociais da Universidade de Lisboa, Universidade de Lisboa, 1600-189 Lisboa, Portugal Núcleo de Estudos em Saúde da População, Universidade Estadual do Sudoeste da Bahia, Itapetinga, Bahia 45700-000 Brasil Casa de Saúde da Idanha, Instituto das Irmãs Hospitaleiras, 2605-077 Belas, Portugal Cognitive-Behavioural Research Centre, Faculty of Psychology and Education Sciences, University of Coimbra, 3001-802 Coimbra, Portugal Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal Centro de Investigação do Núcleo de Estudos e Intervenção Cognitivo Comportamental, Universidade de Coimbra, 3001-802 Coimbra, Portugal Centre for Health Studies and Research, University of Coimbra, 3004-512 Coimbra, Portugal Universidade Federal de Alagoas, Maceió, 57072-900 Alagoas Brasil Instituto Federal de Alagoas, Maceió, 57035-660 Alagoas Brasil Centro Universitário Cesmac, Maceió, 57051-160 Alagoas Brasil Universidade do Porto, Porto, 4099-002 Portugal Universidade de Coimbra, Coimbra, 3004-504 Portugal Escola Superior de Saúde Dr. Lopes Dias, Instituto Politécnico de Castelo Branco, Castelo Branco, 6000-767 Portugal Department for Health Psychology, FernUniversität in Hagen, 58084 Hagen, Germany Universidade Federal do Pará, Belém, Pará 66075-110 Brasil Escola Superior de Saúde, Universidade do Algarve, Faro, 8000-510 Portugal Centro de Estudos e Investigação em Saúde, Faculdade de Economia,, Universidade de Coimbra, 3004-512 Coimbra, Portugal Direção geral de Saúde (DGS), 1049-005 Lisboa, Portugal Instituto Politécnico de Bragança, Bragança, 5300-253 Portugal Centro de Investigação de Montanha, Escola Superior Agrária, 5300-253 Bragança, Portugal Escola Superior Agrária, Instituto Politécnico de Bragança, 5300-253 Bragança, Portugal Centro de Estudos Transdisciplinares para o Desenvolvimento, Universidade de Trás-os-Montes e Alto Douro, 5000-801 Vila Real, Portugal Research Centre for Sports Sciences, Health Sciences and Human Development, University of Trás-os-Montes e Alto Douro, Vila Real, 5001-801 Portugal Department of Sport Sciences, Exercise and Health, University of Trás-os-Montes e Alto Douro, Vila Real, 5001-801 Portugal Polytechnic Institute of Setúbal, 2910-761 Setúbal, Portugal College of Health Technology of Coimbra, Polytechnic Institute of Coimbra, São Martinho do Bispo, 3046-854 Coimbra Portugal Departamento de Farmacologia e Terapêutica, Faculdade de Medicina, Universidade de Coimbra, Coimbra, 3000-548 Portugal Universidade Estadual do Sudoeste da Bahia, Itapetinga, Bahia 45700-000 Brasil Universidade Tiradentes, Aracaju, Sergipe & Laboratório de Biociências da Motricidade Humana, 49030-620 Aracaju, Brazil Escola Superior de Tecnologia e Gestão, Instituto Politécnico de Bragança, 5300-253 Bragança, Portugal Universidade de Lisboa, 1649-003 Lisboa, Portugal Universidade de Aveiro, Aveiro, 3810-193 Portugal Instituto Superior da Maia, 4475-690 Avioso São Pedro, Portugal Centro Interdisciplinar de Estudos de Género, Instituto Superior de Ciências Sociais e Políticas, 1300-663 Lisboa, Portugal College of Health Technology, Polytechnic Institute of Coimbra, São Martinho do Bispo, 3046-854 Coimbra Portugal Universidade de Aveiro, 3810–193 Aveiro, Portugal e Instituto Superior De Serviço Social Do Porto, 44600-362 Sra. da Hora, Portugal School of Health Sciences, Polytechnic Institute of Setúbal, 2910-761 Setúbal, Portugal Institute of Electronics and Informatics Engineering of Aveiro, 3810-193 Aveiro, Portugal Department of Education, University of Aveiro, 3810-193 Aveiro, Portugal Center for Health Technology and Services Research & School of Health Sciences, University of Aveiro, 3810-193 Aveiro, Portugal Pediatrics Emergency Department, Hospital Lusíadas, Porto, 4050 113 Portugal Centro Hospitalar do Baixo Vouga, Aveiro, 3814-501 Portugal Hospital Curry Cabral, Centro Hospitalar Lisboa Central, 1069-166 Lisboa, Portugal Centro de Formação Multiperfil, Luanda, PR - 56Q Angola Center for Health Technology and Services Research, University of Aveiro, Aveiro, 3810-193 Aveiro Portugal Centre of Investigation in Environment, Genetics and Oncobiology, Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal Biomedical Laboratory Sciences Department, University of Gothenburg, S-405 30 Gothenburg, Sweden Biophysics and Biomathematics Institute, Institute for Biomedical Imaging and Life Sciences, Faculty of Medicine, University of Coimbra, 3000-354 Coimbra, Portugal Oncobiology and Haematology Laboratory of Applied Molecular Biology & Clinical University of Hematology, Faculty of Medicine, University of Coimbra, 3000-354 Coimbra, Portugal Radiation Oncology Department, Coimbra Hospital and Universitary Centre, 3000-075 Coimbra, Portugal Clinical University of Hematology, Coimbra Hospital and Universitary Centre, 3000-075 Coimbra, Portugal Imunology Institute, Faculty of Medicine, University of Coimbra, 3000-354 Coimbra, Portugal Escola Superior de Tecnologia da Saúde de Lisboa, Instituto Politécnico de Lisboa, Lisboa, 1549-020 Portugal Department of Clinical Chemistry and Transfusion Medicine, Sahlgrenska University Hospital, Göteborg, 413 45 Göteborg Switzerland Complementary Sciences Department, College of Health Technology of Coimbra, Polytechnic Institute of Coimbra, São Martinho do Bispo, 3046-854 Coimbra, Portugal Medical Laboratory Sciences Department, Al-Quds University, Abu Dis, P.O Box 89, Abu Dis, Palestinian National Authority Blood Bank Service, Coimbra Hospital and Universitary Center, 3000-075 Coimbra, Portugal Escola Superior de Tecnologia e Gestão, Instituto Politécnico de Leiria, 2411-901 Leiria, Portugal Centre for the Research and Technology of Agro-Environmental and Biological Sciences, University of Trás-os-Montes and Alto Douro, 5001-801 Vila Real, Portugal Instituto de Telecomunicações, Instituto Politécnico de Leiria, 2411-901 Leiria, Portugal Escola Superior de Tecnologia da Saúde de Coimbra, São Martinho do Bispo, 3046-854 Coimbra Portugal Escola Superior de Saúde, Universidade de Aveiro, 3810-193 Aveiro, Portugal Center for Health Technology and Services Research, Universidade do Porto, 4200-450 Porto, Portugal Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Porto, 4050-313 Porto Portugal Interdisciplinary Centre of Marine and Environmental Research, Universidade do Porto, 4050-123 Porto, Portugal Centre for Rapid and Sustainable Product Development, Polytechnic Institute of Leiria, 2430-028 Marinha Grande, Portugal Birmingham Hospitals, Birmingham, B15 2GW United Kingdom Instituto Superior de Ciências Sociais e Políticas, 1300-663 Lisboa, Portugal Universidade Fernando Pessoa, Porto, 4249-004 Porto Portugal Faculdade de Engenharia, Universidade do Porto, 4200-465 Porto, Portugal Universidade de Trás-os-Montes e Alto Douro, Vila Real, 5001-801 Vila Real, Portugal Instituto de Engenharia de Sistemas e Computadores, Tecnologia e Ciência, 4200-465 Porto, Portugal Centro de Medicina de Reabilitação da Região Centro - Rovisco Pais, 3064-908 Tocha, Portugal Azores University, São Miguel, 9501-855 Ponta Delgada Portugal Department of Education and Psychology, University of Aveiro, Aveiro, 3810-193 Aveiro Portugal Center for Health Technology and Services Research, Faculty of Medicine, University of Porto, Porto, 4200-450 Porto Portugal Faculty of Psychology and Education Sciences, University of Coimbra, Coimbra, 3000-115 Coimbra Portugal Centro de investigação em educação e ciências do comportamento, Universidade de Aveiro, Aveiro, 3810-193 Aveiro Portugal Instituto de Imagem Biomédica e Ciências da Vida, Faculdade de Medicina, Universidade de Coimbra, Coimbra, 3000-548 Coimbra Portugal Centro de Investigação do Núcleo de Estudos e Intervenção Cognitivo Comportamental, Universidade de Coimbra, Coimbra, 3001-802 Coimbra Portugal Instituto de Ciências da Saúde, Universidade Católica Portuguesa, Lisboa, 1649-023 Lisboa Portugal University of Extremadura, Badajoz, 06071 Badajoz España Flinders Health Economics Group, Flinders University, Adelaide, 5001 Australia Centre for Health Economics, Monash University, Victoria, 3800 Australia Universidade de Évora, 7004-516 Évora, Portugal Centro de Literaturas e Culturas Lusófonas e Europeias, Universidade de Lisboa, 1600-214 Lisboa, Portugal School of Health Sciences, University of Aveiro, Aveiro, 3810-193 Aveiro Portugal Centro Hospitalar do Baixo Vouga, Aveiro, 3814-501 Aveiro, Portugal Escola Superior de Enfermagem do Porto, Porto, 4200-072 Porto Portugal Department of Psychological Medicine, Faculty of Medicine, University of Coimbra, 3000-354 Coimbra, Portugal Unidade de Saúde Familiar – Topázio, Eiras, 3020-171 Coimbra Portugal Instituto Superior Miguel Torga, Coimbra, 3000 Coimbra Portugal University of Aveiro, Aveiro, 3810-193 Aveiro Portugal Instituto de Imagem Biomédica e Ciências da Vida, Faculdade de Medicina, Universidade de Coimbra, 3000-548 Coimbra, Portugal Laboratory of Bioinformatics, Graduate Program in Engineering and Computing, West Paraná State University, Cascavel, Paraná 85819-110 Brasil Universidade Estadual de Campinas, Campinas, São Paulo 13083-970 Brasil Fundação Universidade Regional de Blumenau, Blumenau, Santa Catarina 89012-900 Brasil Departamento de Saúde Pública, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, 1169-056 Lisboa, Portugal Centro de Estudos de Doenças Crónicas, Universidade Nova de Lisboa, 1150-082 Lisboa, Portugal Health Research Unit, Polytechnic institute of Leiria, 2411-901 Leiria, Portugal Universidade Católica Portuguesa, Lisboa, 1649-023 Lisboa Portugal Centro Interdisciplinar de Ciências Sociais, Universidade dos Açores, São Miguel, 9501-855 Ponta Delgada, Região Autónoma dos Açores Portugal Faculdade de Medicina, Universidade José do Rosario Vellano, Divinópolis, Minas Gerais, 35502-634 Brasil Universidade Católica Portuguesa, Lisboa, 1649-023 Lisboa, Portugal Federal University of Ceará, Fortaleza, Ceará 60020-181 Brazil Federal University of Piauí, Teresina, Piauí, 64049-550 Brazil Federal Institute of Education, Science and Technology of Ceará, Fortaleza, Ceará, 60040-531 Brazil Federal University of Cariri, Juazeiro do Norte, Ceará, 63048-080 Brazil Federal University of Cariri, Juazeiro do Norte, Ceará 63048-080 Brazil Centro de Investigação em Psicologia, Escola de Psicologia, Universidade do Minho, 4710-057 Braga, Portugal Cognitive and Behavioural Centre for Research and Intervention, Faculty of Psychology and Educational Sciences, University of Coimbra, 3000-115 Coimbra, Portugal PROACTION Laboratory, 3001-802 Coimbra, Portugal Universidade Católica Portuguesa, Porto, 4202-401 Porto Portugal Cáritas Diocesana de Coimbra - Centro Rainha Santa Isabel, 3030-382 Coimbra, Portugal Cáritas Diocesana de Coimbra, Centro Rainha Santa Isabel, 3030-382 Coimbra Portugal Fundação Mário da Cunha Brito, 3360-908 S. Pedro de Alva, Portugal Escola Superior de Tecnologia da Saúde de Coimbra, Instituto Politécnico de Coimbra, São Martinho do Bispo, 3046-854 Coimbra, Portugal Centro de Estudos e Investigação em Saúde da Universidade Coimbra, Faculdade de Economia, Universidade de Coimbra, 3004-512 Coimbra, Portugal Universidade Federal de São Paulo, São Paulo, 04021-001 Brasil Escola superior de Ciências da Santa Casa de Misericórdia de Vitória, Vitória- Esprito Santo, 29045-402 Brasil Faculdade Católica Salesiana do Espírito Santo, Vitória- Esprito Santo, 29017-950 Brasil Cognitive-Behavioural Research Centre, Faculty of Psychology and Education Sciences, University of Coimbra, Coimbra, 3001-802 Coimbra Portugal Cognitive and Behavioural Centre for Research and Intervention, Faculty of Psychology and Education Sciences, University of Coimbra, Coimbra, 3000-115 Coimbra Portugal Centro de Estudos em Saúde, Escola Superior de Saúde, Universidade do Algarve, 8000-510 Faro, Portugal Escola Superior de Enfermagem de Coimbra, Coimbra, 3046-851 Coimbra Portugal Centro Hospitalar do Porto, Porto, 4099-001 Porto Portugal Universidade do Estado do Rio de Janeiro, Rio de Janeiro, 20550-900 Brasil Faculdade de Farmácia, Universidade de Lisboa, 1649-003 Lisboa, Portugal Unidade de Saúde Pública, Centro Hospitalar do Baixo Vouga, Aveiro, 3814-501 Portugal Centro Hospitalar do Porto, Porto, 4099-001 Portugal Center for Health Technology and Services Research, Faculty of Medicine, University of Porto, Porto, 4099-002 Portugal Centro Hospitalar Tâmega e Sousa, Penafiel, 4564-007 Portugal Centro de Investigação em Desporto, Saúde e Desenvolvimento Humano, Escola Superior de Saúde, Instituto Politécnico de Bragança, Bragança, 5300-253 Portugal Centro de Estudos em Educação, Tecnologias e Saúde, Escola Superior de Educação de Viseu, 3504-501 Viseu, Portugal Universidade Católica Portuguesa – Porto, 4202-401 Porto, Portugal Unidade Local de Saúde do Nordeste, Bragança, 5301-852 Portugal Instituto de Ciências da Saúde, Universidade Católica Portuguesa, Porto, 4202-401 Porto Portugal Escola Superior de Saúde, Instituto Politécnico de Santarém, Santarém, 2005-075 Santarém, Portugal Instituto Politécnico de Castelo Branco, 6000-767 Castelo Branco, Portugal Research in Education and Community Intervention, Instituto Piaget, 3515-776 Galifonge, Viseu Portugal Universidad de Extremadura, 10003 Cáceres, España Centro Universitário Franciscano, Santa Maria, Rio Grande do Sul 97010-032 Brasil Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul 97105-900 Brasil Unidade de Transplante Hepático e Pancreático, Centro Hospitalar do Porto, 4099-001 Porto, Portugal Universidade Estadual Paulista ‘Júlio de Mesquita Filho”, 01049-010 São Paulo, Brazil Universidade do Sul de Santa Catarina, Palhoça, Santa Catarina 88137-270 Brazil Coimbra Chemistry Centre, Chemistry Department, University of Coimbra, 3004-535 Coimbra, Portugal MARE, Instituto Politécnico de Leiria, Peniche, 2520-641 Portugal Hospital Arcebispo João Crisóstomo, Cantanhede, 3060 Cantanhede Portugal Hospital José Luciano de Castro, Anadia, 3780-226 Anadia Portugal Hospital de Aveiro, Centro Hospitalar do Baixo Vouga E.P.E., Aveiro, 3814-501 Portugal Instituto de Medicina Preventiva, Faculdade de Medicina de Lisboa, Universidade de Lisboa, 1649-028 Lisboa, Portugal Faculty of Health Sciences, University of Beira Interior, Covilhã, 6200-506 Covilhã Portugal Health Sciences Research Centre, University of Beira Interior, Covilhã, 6200-506 Covilhã Portugal Centre for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal Universidade do Vale do Paraíba, São José dos Campos, São Paulo 12244-000 Brasil Maternidade Daniel de Matos, Centro Hospitalar e Universitário de Coimbra, 3000-075 Coimbra, Portugal Hospital Dr. Nélio Mendonça, Região Autónoma da Madeira, Funchal, 9004-514 Portugal Universidade New Atlântica, 2745-615 Barcarena, Portugal Universidade Federal do Amapá, Macapá, Amapá 68903-419 Brasil Universidade Federal do Sergipe, São Cristóvão, Sergipe 49100-000 Brasil Centro Hospitalar de Trás –os-Montes e Alto Douro, Vila Real, 5000-508 Portugal Escola Superior de Enfermagem de Vila Real, Universidade de Trás –os-Montes e Alto Douro, Vila Real, 5000-232 Lordelo Portugal Health Sciences Research Centre, Faculty of Health Sciences, University of Beira Interior, Covilhã, 6201-001 Portugal Unidade de Investigação Aplicada em Gestão, Instituto Politécnico de Bragança, Bragança, 5300-253 Portugal Research Unit in Business Sciences, University of Beira Interior, Covilhã, 6201-001 Portugal Escola Superior de Tecnologia da Saúde do Porto, Instituto Politécnico do Porto, Vila Nova de Gaia, 4400-330 Vila Nova de Gaia, Portugal Universidade Federal da Bahia, Salvador da Bahia, 0170-115 Brazil Centro de Investigação e de Tecnologias Agro-Ambientais e Biológicas, Universidade de Trás-os-Montes e Alto Douro, 5001-801 Vila Real, Portugal & Universidade do Minho, 4704-553 Braga, Portugal Universidade da Beira Interior, Covilhã, 6201-001 Covilhã, Portugal Associação de Melhoramentos Pró Outeiro, Oliveira de Azeméis, 3720-514 Santiago de Riba-Ul Portugal School of Education, Polytechnic Institute of Setúbal, 2910-761 Setúbal, Portugal Centro Interdisciplinar da Performance Humana, Faculdade de Motricidade Humana, Universidade de Lisboa, 1499-002 Cruz Quebrada, Portugal Research Centre Sports Sciences, Health Sciences and Human Development, University of Trás-os-Montes e Alto Douro, Vila Real, 5001-801 Vila Real, Portugal Escola Superior de Saúde de Bragança, Instituto Politécnico de Bragança, 5300-121 Bragança, Portugal Centro de Investigação em Saúde e Ambiente, Instituto Politécnico do Porto, Vila Nova de Gaia, 4400-330 Vila Nova de Gaia, Portugal Secção Autónoma das Ciências da Saúde, Universidade de Aveiro, Aveiro, 3810-193 Aveiro, Portugal UCBIO-REQUIMTE Rede de Química e Tecnologia, 4051-401 Porto, Portugal Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Porto, 4050-313 Porto Portugal Department of Legal Medicine and Forensic Sciences, Faculty of Medicine, University of Porto, Porto, 4200-319 Porto Portugal Pharmaceutical Services, Centro Hospitalar de Vila Nova de Gaia/Espinho, EPE, Vila Nova de Gaia, 4400-129 Vila Nova de Gaia, Portugal Escola Superior de Tecnologia da Saúde do Porto, Instituto Politécnico do Porto, Vila Nova de Gaia, 4400-330 Vila Nova de Gaia Portugal Research Centre for Sports Sciences, Health Sciences and Human Development, University of Trás-os-Montes e Alto Douro, Vila Real, 5001-801 Vila Real Portugal Department of Sport Sciences, Exercise and Health, University of Trás-os-Montes e Alto Douro, Vila Real, 5001-801 Vila Real Portugal Centro de Estudos Sociais, Universidade de Coimbra, 3000-995 Coimbra, Portugal GyM Prevención, Burgos, 09007 Burgos, España Universidad de Burgos, 09001 Burgos, España Faculdade de Medicina da Universidade de Lisboa, Lisboa, 1649-028 Lisboa Portugal Hospital Beatriz Ângelo, Loures, 2674-514 Loures Portugal Universidad Autonoma de Chile, Talca, 1670 Talca Chile Escola Superior de Saúde, Instituto Politécnico de Bragança, Bragança, 5300-121 Bragança Portugal Unidade de Investigação UFP em Energia, Ambiente e Saúde & Centro de Estudos em Biomedicina, Fundação Fernando Pessoa, Porto, 4249-004 Porto Portugal REQUIMTE/LAQV, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, 4050-313 Porto, Portugal Escola Superior de Enfermagem, Universidade do Minho, Braga, 4710-057 Braga Portugal Life Quality Research Centre, Polytechnic Institute of Santarém, 2001-904 Santarém, Portugal Polytechnic Institute of Leiria, 2411-901 Leiria, Portugal Jönköping University Foundation, 551 11 Jönköping, Sweden ACES Pinhal Litoral, ARS Centro, Coimbra, 3001-553 Coimbra Portugal Instituto Superior de Ciências Policiais e Segurança Interna, 1349-040 Lisboa, Portugal Escola Superior de Tecnologia da Saúde de Coimbra, Instituto Politécnico de Coimbra, São Martinho do Bispo, 3046-854 Coimbra Portugal Secretaria de estado da saúde de Santa Catarina, Florianópolis, Santa Catarina 88015-130 Brasil Hospital Pêro da Covilhã, Centro Hospitalar Cova da Beira EPE, 6200-251 Covilhã, Portugal Centro de Investigação em Saúde e Ambiente, Instituto Politécnico do Porto, Vila Nova de Gaia, 4400-330 Vila Nova de Gaia Portugal Serviços farmacêuticos, Hospital Pedro Hispano, Unidade Local de Saúde de Matosinhos, EPE, 4454 509 Senhora da Hora, Portugal Faculdade Nobre, Feira de Santana, Bahia, 44001-008 Brasil Secretaria de Saúde do Estado da Bahia, Salvador, Bahia, 41745-900 Brasil Escola Superior de Tecnologia da Saúde, Instituto Politécnico do Porto, Vila Nova de Gaia, 4400-330 Vila Nova de Gaia Portugal Instituto Português de Oncologia do Porto FG, EPE, Porto, 4200-072 Porto Portugal Centro Hospitalar São João, Porto, 4200-319 Porto Portugal Universidade de São Paulo, São Paulo, 05403-000 Brasil VOID – Software Development, 2415-767 Leiria, Portugal Centre for Research in Informatics and Communications, Polytechnic Institute of Leiria, 2411-901 Leiria, Portugal Instituto de Engenharia de Sistemas e Computadores de Coimbra, 3000-033 Coimbra, Portugal Nova Medical School, Universidade Nova de Lisboa, 1169-056 Lisboa, Portugal Escola Nacional de Saúde Publica, Lisboa, 1600-560 Lisboa Portugal Escola Superior de Tecnologia e Saúde, Instituto Politécnico do Porto, 4400-330 Vila Nova de Gaia, Portugal Escola Nacional de Saúde Pública, Lisboa, 1600-560 Lisboa Portugal Escola Superior de Saúde, Instituto Politécnico de Portalegre, Portalegre, 7301-901 Portalegre Portugal Faculdade de Medicina Dentária, Universidade de Lisboa, Lisboa, 1649-003 Lisboa Portugal Escola Superior de Saúde, Instituto Politécnico de Leiria, 2411-901 Leiria, Portugal Department of Biomedical Sciences, University of Applied Sciences Salzburg, A-5412 Puch, Salzburg Austria Department of Medical and Bioinformatics, University of Applied Sciences Upper Austria, Hagenberg, A-4232 Hagenberg Austria Center for Health Technology and Services Research, Faculty of Medicine, University of Porto, 4099-002 Porto, Portugal Centro Hospitalar de Trás–os-Montes e Alto Douro, Vila Real, 5000-508 Portugal Centro de Investigação em Saúde Pública, Escola Nacional de Saúde Publica, 1600-560 Lisboa, Portugal Escola Superior de Saúde de Leiria eCADR& Centro de Investigação Didática e Tecnologia na Formação de Formadores, Universidade de Aveiro, 3810-193 Aveiro, Portugal Unidade de Saúde Pública - ACES Pinhal Litoral, ARS Centro, 3100-462 Pombal, Portugal Consulta Externa de Pediatria, Centro Hospitalar de Leiria, 2410-197 Leiria, Portugal Universidade do Oeste do Paraná, Foz do Iguaçu, Paraná 85851-100 Brasil Centro de Investigação Interdisciplinar em Saúde, Universidade Católica Portuguesa/Porto, 4202-401 Porto, Portugal Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Cooperativa De Ensino Superior Politécnico Universitário, Instituto Politécnico de Saúde do Norte, 4585-116 Gandra, Portugal Escola Superior de Enfermagem do Porto, Porto, 4200-072 Porto, Portugal Centre for Health Technology and Services Research, Faculdade de Medicina da Universidade do Porto, 4200-450 Porto, Portugal University Thomas More, B - 2800 Mechelen, Belgium Instituto Português do Sangue e da Transplantação, Lisboa, 1000-208 Portugal Facultad de Terapia Ocupacional, Logopedia y Enfermería, Universidad de Castilla-La Mancha, 45600 Talavera de la Reina, Toledo España AN - 27409075 AU - Tomás, C. 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C2 - PMC4943498 DA - Jul 6 DO - 10.1186/s12913-016-1423-5 DP - NLM ET - 2016/07/15 IS - Suppl 3 LA - eng N1 - 1472-6963 Tomás, Catarina Cardoso Oliveira, Emanuel Sousa, D Uba-Chupel, M Furtado, G Rocha, C Teixeira, A Ferreira, P Alves, Celeste Gisin, Stefan Catarino, Elisabete Carvalho, Nelma Coucelo, Tiago Bonfim, Luís Silva, Carina Franco, Débora González, Jesús Alcoba Jardim, Helena G Silva, Rita Baixinho, Cristina L Presado, Mª Helena Marques, Mª Fátima Cardoso, Mário E Cunha, Marina Mendes, Joana Xavier, Ana Galhardo, Ana Couto, Margarida Frade, João G Nunes, Carla Mesquita, João R Nascimento, Maria S Gonçalves, Guilherme Castro, Conceição Mártires, Alice Monteiro, Mª João Rainho, Conceição Caballero, Francisco P Monago, Fatima M Guerrero, Jose T Monago, Rocio M Trigo, Africa P Gutierrez, Milagros L Milanés, Gemma M Reina, Mercedes G Villanueva, Ana G Piñero, Ana S Aliseda, Isabel R Ramirez, Francisco B Ribeiro, Andrea Quelhas, Ana Manso, Conceição Santos, Rafael B Jimenez, Nuria R Nuñez, Cristina G Gomez, Inmaculada R Fernandez, Mª Jose L Marquez, Laura A Moreno, Ana L Huertas, Mª Jesus Tena Seabra, Daniel Salvador, Mª Céu Braga, Luciene Parreira, Pedro Salgueiro-Oliveira, Anabela Arreguy-Sena, Cristina Oliveira, Bibiana F Henriques, Mª Adriana Santos, Joana Lebre, Sara Marques, Alda Festas, Clarinda Rodrigues, Sandra Lumini, José Figueiredo, Ana G Hernandez-Martinez, Francisco J Campi, Liliana Quintana-Montesdeoca, Mª Pino Jimenez-Diaz, Juan F Rodriguez-De-Vera, Bienvenida C Parente, Alexandra Mata, Mª Augusta Pereira, Ana Mª Fernandes, Adília Brás, Manuel Pinto, Mª Rosário Basto, Marta L Rei, Ana C Mónico, Lisete M Sousa, Gilberta Morna, Clementina Freitas, Otília Freitas, Gregório Jardim, Ana Vasconcelos, Rita Horta, Lina G Rosa, Roger S Kranz, Luís F Nugem, Rita C Siqueira, Mariana S Bordin, Ronaldo Kniess, Rosiane Lacerda, Josimari T Guedes, Joana Machado, Idalina Almeida, Sidalina Zilhão, Adriano Alves, Helder Ribeiro, Óscar Amaral, Ana P Santos, Ana Monteiro, Joana Rocha, Mª Clara Cruz, Rui Lourenço, Marina Antunes, Sandra Mendonça, Verónica Andrade, Isabel Osório, Nádia Valado, Ana Caseiro, Armando Gabriel, António Martins, Anabela C Mendes, Fernando Cabral, Lídia Ferreira, Manuela Gonçalves, Amadeu Luz, Tatiana D Luz, Leonardo Martins, Raul Morgado, Alice Vale-Dias, Maria L Porta-Nova, Rui Fleig, Tânia C Reuter, Éboni M Froemming, Miriam B Guerreiro, Sabrina L Carvalho, Lisiane L Guedelha, Daniel Coelho, P Pereira, A Calha, António Cordeiro, Raul Gonçalves, Ana Certo, Ana Galvão, Ana Welter, Aline Pereira, Elayne Ribeiro, Sandra Kretzer, Marcia Jiménez-Díaz, Juan-Fernando Jiménez-Rodríguez, Carla Hernández-Martínez, Francisco-José Rodríguez-De-Vera, Bienvenida-Del-Carmen Marques-Rodrigues, Alexandre Coelho, Patrícia Bernardes, Tiago Pereira, Alexandre Sousa, Patrícia Filho, João G Nazario, Nazare Amaral, Odete Garrido, António Veiga, Nélio Pedro, Ana R Pereira, Carlos Almeia, António Fernandes, Helder M Vasconcelos, Carlos Sousa, Nelson Reis, Victor M Monteiro, M João Mendes, Romeu Pinto, Isabel C Pires, Tânia Gama, João Preto, Vera Silva, Norberto Magalhães, Carlos Martins, Matilde Duarte, Mafalda Paúl, Constança Martín, Ignácio Pinheiro, Arminda A Xavier, Sandra Azevedo, Julieta Bento, Elisabete Marques, Cristiana Marques, Mariana Macedo, António Pereira, Ana T Almeida, José P Almeida, António Alves, Josiane Saavedra, Francisco Maia, Ana S Oliveira, Michelle T Sousa, Anderson R Ferreira, Paulo P Lopes, Luci S Santiago, Eujcely C Monteiro, Sílvia Jesus, Ângelo Colaço, Armanda Carvalho, António Silva, Rita P Cruz, Agostinho Ferreira, Ana Marques, Catarina Figueiredo, João P Paixão, Susana Lopes, Carla Moreira, Fernando Ribeiro, Diana Fernandes, Telma Amado, Diogo Leal, Jéssica Azevedo, Marcelo Ramalho, Sónia Mangas, Catarina Ribeiro, Jaime Gonçalves, Rita Nunes, Amélia F Tuna, Ana R Martins, Carlos R Forte, Henriqueta D Costa, Cláudia Tenedório, José A Santana, Paula Andrade, J A Pinto, J L Campofiorito, C Nunes, S Carmo, A Kaliniczenco, A Alves, B Mendes, F Jesus, C Fonseca, F Gehrke, F Albuquerque, Carlos Batista, Rita Cunha, Madalena Madureira, António Ribeiro, Olivério Martins, Rosa Madeira, Teresa Peixoto-Plácido, Catarina Santos, Nuno Santos, Osvaldo Bergland, Astrid Bye, Asta Alarcão, Violeta Goulão, Beatriz Mendonça, Nuno Nicola, Paulo Clara, João G Gomes, João Querido, Ana Tomás, Catarina Carvalho, Daniel Cordeiro, Marina Rosa, Marlene C Brandão, Daniela Araújo, Lia Minghelli, Beatriz Richaud, Sylvina Mendes, Ana L Marta-Simões, Joana Trindade, Inês A Ferreira, Cláudia Carvalho, Teresa Pinto-Gouveia, José Fernandes, Morgana C Medeiros, Anabela Pimentel, Rafaela Fernandes, Andreia Mendonça, Carlos Andrade, Susana Menezes, Ruth L Bravo, Rafael Miranda, Marta Ugartemendia, Lierni Tena, José Mª Pérez-Caballero, Francisco L Fuentes-Broto, Lorena Rodríguez, Ana B Carmen, Barriga Carneiro, M A Domingues, J N Paixão, S Figueiredo, J Nascimento, V B Azzalis, L Martins, Ana R Nunes, Amélia Jorge, Arminda Amorim, Ana Silva, André Martinho, Liliana Monteiro, Luís Silva, Rafael Coelho, Carina Coelho, Inês Correia, André Rodrigues, Diana Marante, Nídia Silva, Pedro Carvalho, Sara Araujo, André Rts Ribeiro, Maximiano Coutinho, Paula Ventura, Sandra Roque, Fátima Calvo, Cristina Reses, Manoela Conde, Jorge Figueiredo, João Silva, David Seiça, Luís Soares, Raquel Mourão, Ricardo Kraus, Teresa Abreu, Ana C Padilha, José M Alves, Júlia M Sousa, Paulino Oliveira, Manuel Sousa, Joana Novais, Sónia Mendes, Felismina Pinto, Joana Cruz, Joana Duarte, Hugo Dixe, Maria Dos Anjos Sousa, Pedro Cruz, Inês Bastos, Fernanda Pereira, Filipe Carvalho, Francisco L Oliveira, Teresa T Raposo, Vítor R Ribeiro, José C Barroso, Isabel Rodrigues, Vítor Neves, Carmo Oliveira, Teresa C Oliveira, Bárbara Morais, Mª Carminda Baylina, Pilar Rodrigues, Rogério Azeredo, Zaida Vicente, Corália Dias, Hélia Sim-Sim, Margarida Castilho, Amélia Melo, Rosa Graveto, João Gomes, José Vaquinhas, Marina Carvalho, Carla Mónico, Lisete Brito, Nuno Sarroeira, Cassilda Amendoeira, José Cunha, Fátima Cândido, Anabela Fernandes, Patrícia Silva, Helena R Silva, Elsa Lapa, Leila Antunes, Cristina Gomes, Mª José Escanciano, Susana R Freitas, Maria Marôco, João Fernandes, Ana R Cabral, Cremilde Alves, Samuel Ferreira, António Príncipe, Fernanda Seppänen, Ulla-Maija Ferreira, Margarida Carvalhais, Maribel Silva, Marilene Silva, Joana Neves, Jéssica Costa, Diana Santos, Bruno Duarte, Soraia Marques, Sílvia Mendes, Isabel Louro, Clarisse Menino, Eva Dixe, Maria Dias, Sara S Valim, Frederico C Costa, Joyce O Bernardes, Lúcia G Prebianchi, Helena Rosa, Marlene Cristina Gonçalves, Narcisa Martins, Maria M Kurcgant, Paulina Vieira, André Bento, Sandrina Deodato, Sérgio Rabiais, Isabel Reis, Laura Torres, Ana Soares, Sérgio Graça, Pedro Leitão, Céu Abreu, Renato Bellém, Fernando Almeida, Ana Ribeiro-Varandas, Edna Tavares, Ana Henriques, Carolina Jordão, Célia Neco, Sofia Morais, Carminda Ferreira, Pedro Silva, Carla R Brito, Alice Silva, Antónia Postolache, Gabriela Oliveira, Raul Moreira, Isabel Pedro, Luísa Vicente, Sónia Domingos, Samuel Postolache, Octavian Silva, Darlen Schneider, Dulcineia Marques, Fátima M Pinto, Carlos Vicente, Sara Breda, São João Gomes, José H Salgueiro, Anabela Duarte, Nuno Lopes, José C Nunes, Hélder Braga, Luciene M Araújo, Beatriz Alves, José M Sousa, Ana S Ferrito, Cândida Ferreira, Pedro L Rodrigues, Alexandre Oliveira, Isabel Martins, Cristina Macedo, Ana P Araújo, Odete Augusto, Cláudia Braga, Fátima Gomes, Lisa Silva, Maria A Rosário, Rafaela Pimenta, Luís Carreira, Diana Teles, Patrícia Barros, Teresa Jácome, Cristina Capelas, Sylvie Hall, Andreia Alves, Dina Lousada, Marisa Loureiro, Mª Helena Camarneiro, Ana Silva, Margarida Mendes, Aida Pedreiro, Ana G.Silva, Anne Coelho, Elza S Melo, Flávio Ribeiro, Fernando Torres, Rui Costa, Rui Pinho, Tânia Cruz, Bárbara Carreiras, Diogo Ventura, Maria Cruz, x Brooks, Dina Pinto, M Rosário Lima-Basto, Marta Neves, Miguel Bizarro, Carla Margarida, Couto Amorim, Ana P Silva, Eduardo Cruz, Susana Valente, Jorge Guerrero, José T Gonzalez, Estefania P Monago, Fátima M Ugalde, Lierni U Vélez, Marta M Tena, Maria J Becerra, Isabel A Agudelo, Mª Elizabeth Acedo, Guadalupe Bajo, Roberto Malheiro, Isabel Gaspar, Filomena Barros, Luísa Furtado, Guilherme Uba-Chupel, Mateus Rama, Luís Braga, Margarida Ferreira, José P Teixeira, Ana Mª Cruz, João Barbosa, Tiago Simões, Ângela Coelho, Luís Martinez-Hernandez, Francisco Rodriguez-De-Vera, Bienvenida Rodrigues, Alexandrina Ramalho, André Petrica, João Mendes, Pedro Serrano, João Santo, Inês Rosado, António Mendonça, Paula Freitas, Kátia Ferreira, Dora Brito, António Fernandes, Renato Gomes, Sofia Pinho, Cláudia Oliveira, Rita Oliveira, Ana I Casimiro, Ana P Martins, Patrícia Silva, Iryna Evangelista, Diana Leitão, Catarina Velosa, Fábia Carecho, Nélio Dixe, Anjos Catarino, Helena Soares, Fátima Gama, Ester Gordo, Clementina Moreira, Eliana Midões, Cristiana Santos, Marlene Machado, Sara Oliveira, Vânia P Marques, Rita Charepe, Zaida Antunes, Ana Santos, Sofia Marques, Silvana F CaroMinghelli, Eulália Luís, Mª José Brandão, Teresa Marinho, Daniel Monteiro, Diogo Paulo, Rui Monteiro, Lina Ramalho, Fátima Santos-Rocha, Rita Morgado, Sónia Bento, Teresa Silva, Isabel Azevedo, Tatiana Soares, Salete Pisco, Jacinta Olszewer, Efrain O Oliveira, Sebastião T Santos, Erica Maia, Carla Mendes, Maria F Oliveira, Rita F Barreira, Eduarda Pereira, Ana Vaz, Josiana A Novo, André Silva, Luís D Maia, Bruno Ferreira, Eduardo Pires, Filipa Andrade, Renato Camarinha, Luís César, Ana F Poço, Mariana Ventura, David Loura, Raquel Gomes, Pedro Gomes, Catarina Silva, Cláudia Melo, Elsa Lindo, João Domingos, Joana Mendes, Zaida Poeta, Susana Carvalho, Tiago Dixe, Mª Anjos Garcia, Inês Meneses, Rui Afonso, Carlos Faria, Luís Seixas, Adérito Granjo, Paulo Gomes, José C Souza, Nelba R Furtado, Guilherme E Rocha, Saulo V Silva, Paula Carvalho, Joana Morais, Marina Ana Lebre, Paula Alencar, Liana Cardoso, Ilda Daniel, Fernanda Luz, Tatiana Ramos, Maurício R Medeiros, Dayse C Carmo, Bruno M Seabra, André Padez, Cristina Silva, Manuel C Rodrigues, António Coelho, Alexandre Caminha, Madson Matheus, Filipe Mendes, Elenice Correia, Jony Rodriguez-De-Vera, Bienvendida C Jimenez-Rodriguez, Carla Armas-Gonzalez, Yadira Rodrigues, Cátia Pedroso, Rosa Apolinário-Hagen, Jennifer Vehreschild, Viktor Veloso, Milene Magalhães, Celina Cabral, Isabel Ferraz, Maira Nave, Filipe Costa, Emília Matos, Filomena Pacheco, José Dias, António Duarte, João Silva, Daniel Alferes, Valentim R Brêda, Mª São João Parreira, Pedro M Pimenta, Rui Boavida, José Silva, Catarina Ribeiro, Maria Viega-Branco, Maria Pereira, Filomena Almeida, Fabrícia M Estevez, Gustavo L Kretzer, Marcia R João, Paulo V Nogueira, Paulo Novais, Sandra Carneiro, Lara Mota, Maria Santiago, Luiz Fontes-Ribeiro, Carlos Coutinho, André P Neto, João S Vasconcelos, Lélia R Dantas, Estélio Dinis, Alexandra Carvalho, Sérgio Castilho, Paula Sarreira-Santos, Alexandra Figueiredo, Amélia Medeiros-Garcia, Lurdes Seabra, Paulo Rodrigues, Rosa Fernandes, Paula O Santiago, Conceição Figueiredo, Mª Henriqueta Guimarães, Teresa Coelho, André Graça, Anabela Silva, Ana M Fonseca, Ana R Vale-Dias, Luz Minas, Bárbara Franco-Borges, Graciete Simões, Cristina Serra, Ana Matos, Maria Jesus, Luís Tavares, Ana S Varandas, Edna Miranda, Cristiana Guimarães, Pedro Gonçalves, Rodrigo San-Martin, Elisabete A Goulart, Cássia L Schneiders, Paloma B Miranda, Natacha F Silva, Andrea G Topa, Joana Nogueira, Conceição Neves, Sofia Ventura, Rita Nazaré, Cristina Freitas, Alberto Mercê, Cristiana Branco, Marco Almeida, Pedro Nascimento, Daniela Pereira, Juliana Catela, David Rafael, Helga Reis, Alcinda C Mendes, Ana Valente, Ana R Sousa, Diana Baltazar, Ana L Oliveira, Ana Aparício, José Neves, Joana Ayoub, Rodrigo Sousa, Luís Marques-Vieira, Cristina Severino, Sandy José, Helena Cadorio, Inês Andrade, Diogo Domingues, Cátia Schukg, Susann Abrantes, Ana M Gonçalves, Ana C Sales, Tiago Teixo, Ricardo Estrela, Jéssica Laranjo, Mafalda Casalta-Lopes, João Rocha, Clara Simões, Paulo C Sarmento-Ribeiro, Ana B Botelho, Mª Filomena Rosa, Manuel S Fonseca, Virgínia Colaço, Diogo Neves, Vanessa Jesus, Carlos Hesse, Camilla Svensson, Lola Siba, Wafa A Pereira, Cristina Tomaz, Jorge Duarte, Diana Lopes, Nuno V Fonseca-Pinto, Rui Brandão, Piedade Martins, Laura Cardoso, Margarida Morais, Nuno Alves, Nuno Faria, Paula Mateus, Artur Morouço, Pedro Ferreira, Nelson Cardoso, Andreia Lopes, Albino Soares, Valter Dias, Tiago Vardasca, Ricardo Gabriel, Joaquim Paredes, Hugo Reis, Arsénio Marinho, Sara Filipe, Vítor Lains, Jorge Barroso, João Da Motta, Carolina Carvalho, Célia B Peixoto, Ermelindo Gomes, Ana A Costa, Vanessa Couto, Diana Marques, Daniel R Leitão, José A Tavares, José Azevedo, Maria H Silva, Carlos F Freitas, João Garcia-Gordillo, Miguel A Collado-Mateo, Daniel Chen, Gang Iezzi, Angelo Sala, José A Parraça, José A Gusi, Narcis Sousa, Jani Jardim, Jacinto Pereira, Anabela Simões, Sónia Sardo, Pedro Guedes, Jenifer Machado, Paulo Benevides, Joana Sousa, Marina Cabral, Joana Carvalho, Rosa Alves, Juliana Azevedo, Mª Helena Silva, Carlos Lee, Huei D Spolaôr, Newton Oliva, Jefferson T Chung, Wu F Bairros, Keila Silva, Cláudia D Souza, Clóvis A Schroeder, Silvana S Araújo, Elsa Monteiro, Helena Costa, Ricardo Torgal, Jorge Henriques, Carolina G Santos, Luísa Caceiro, Elisa F Ramalho, Sónia A Afreixo, Vera Santos, João Mota, Priscilla Pimentel, Francisco Caldeira, Suzana N Ribeiro, Lígia C Aquino, Priscila S Ribeiro, Samila G Pinheiro, Ana B Lessa, Paula A Oliveira, Mirna F Brito, Luísa S Pinto, Ítalo N Furtado, Alessandra S Castro, Régia B Aquino, Caroline Q Martins, Eveliny S Oliveira, Lara L Pinheiro, Patrícia C Sousa, Caroline R Freitas, Vívien A Silva, Tatiane M Lima, Adman S Andrade, Karizia V Oliveira, Camila A Vidal, Eglidia F Ganho-Ávila, Ana Moura-Ramos, Mariana Gonçalves, Óscar Almeida, Jorge Silva, Armando Brito, Irma Amado, João Rodrigo, António Gomes, Fernando Luís, Sara Cavalheiro, Luís Gonçalves, Rui Lopes, Rui S Fiorin, Bruno H Santos, Marina S Oliveira, Edmar S Moreira, Rita L Oliveira, Elizabete A Filho, Braulio L Palmeira, Lara Garcia, Teresa Cardoso, Sara Oliveira, Sara Campos, Mariana Gaudêncio, Iris Martins, Fernando Ferreira, Lino Lopes, Nuno Marques, Ana R Carvalho, Rui Costa, Pablo O Silva, Maiza M Alvarenga-Martins, Nathália Pinto, Paulo F Oliveira, Denize C Parreira, Pedro D Gomes, Antônio T Lage, Isabel Cabrita, José Teixeira, Laetitia Silva, Sara Cordeiro, Eugénio Pimentel, João Ferro-Lebres, Vera Souza, Juliana A Tavares, Mariline Passadouro, Rui Peralta, Teresa Ferreira, Carlos Lourenço, Georgina Honório, Samuel Simões, Alexandra Carvalho, Lucinda Figueiredo, Daniela Valente, Carolina Ribas, Patrícia Brandão, Frederico Sousa, Cesar Mendes, Francisco Fernandes, Rosina Martins, Emília Magalhães, Cátia Araújo, Patrícia Grande, Carla Vieitez, Juan G Bianchini, Bruna Costa, Tânia Almeida, Armando Baffour, Gabriel Laranjeira, Carlos Guerra, Magda Barbeiro, Ana P Ferreira, Regina Lopes, Sara Nunes, Liliana Martins, Julian Magajewski, Flávio Soares, Célia Marques, António Batista, Marco Castuera, Ruth J Mesquita, Helena Faustino, António Santos, Jorge Vizzotto, Betina P Frigo, Leticia Pivetta, Hedioneia F Sardo, Dolores Abreu, Wilson Figueiredo, Mª Céu Jimenez-Castuera, Ruth Silveira, Paulo Oliveira, Catarina Rodriguez, Cláudia K Kretzer, Márcia R Nazário, Nazaré O Cruz, Pedro Vaz, Daniela C Ruben, Rui B Avelelas, Francisco Silva, Susana Campos, Mª Jorge Almeida, Maria Gonçalves, Liliana Antunes, Lígia Simões, João Cardoso, Susana Loureiro, Isabel Santos, Flávia Alves, Gilberto Soar, Cláudia Marsi, Teresa O Silva, Ernestina Pedrosa, Dora Leça, Andrea Gomes, Maria Fernandes, Paula Noné, Ana Combadão, Jaime Ramalhete, Cátia Figueiredo, Paulo Caeiro, Patrícia Fontana, Karine C Machado, Patrícia O Borges, Raphaelle Barbosa, Flávio Sá, Dayse Brunhoso, Germana Aparício, Graça Carvalho, Amâncio Garcia, Ana P Santos, Adriana Brás, Carina Carvalho, Inês Batalha, Joana Glória, Margarida Bexiga, Filipa Paraíso, Nilson Lima, Cristóvão F Dias, Alberto P Espada, Mário Marques, Mário Veiga-Branco, Mª Lima, Vera Cruz, Graça Barreiros, Luísa Duarte, Catarina Lima, Teresa Maneca Medina, María S Blanco, Valeriana G Lopes, Elisa Virgolino, Ana Ambrósio, Sara Almeida, Inês Marques, Tatiana Heitor, Mª João Olivares, Pedro R Oliveira, Anabela Cheio, Mónica Pereira, Olívia R Pinto, Sara Oliveira, Adriana Manso, M Conceição Sousa, Carla Vinha, Ana F Machado, Mª Manuela Vieira, Margarida Fernandes, Beatriz Tomás, Teresa Quirino, Diogo Desouzart, Gustavo Matos, Rui Bordini, Magali Mouroço, Pedro Matos, Ana R Serapioni, Mauro Costa, André Ribeiro, João Lobato, João Martin, Inmaculada Z Björklund, Anita Tavares, Aida I Tavares, Nuno Valente, João Ortiga, Angela B Calvo, Mª Cristina Natal, Sônia Pereira, Marta Prata, Ana R Nelas, Paula Carneiro, Juliana Couto, Cristina Souza, Géssica M Almada, Lívia F Conceição, Milena A Domingues, Gabriela Ferreira, Irina Costa, Ana R Cardoso, Américo Meireles, Alexandra Vieira, Viviane L Vincha, Kellem R Cervato-Mancuso, Ana Mª Faria, Melissa Reis, Cláudia Cova, Marco P Ascenso, Rita T Almeida, Henrique A Oliveira, Eunice G Santana, Miguel Pereira, Rafael Jesus, Rita Tapadas, Rodrigo Tim-Tim, Carolina Cezanne, Catarina Lagoa, Matilde Lopes, João Almeida, Henrique Amado, Sandra Carrão, Luís Saboga-Nunes, Luís Oliveira, Suzete Escoval, Ana Assunção, Victor Luís, Henrique Luís, Luís Fotschl, Ulrike Lirk, Gerald Silva, Paula A Ruivo, Joana Silva, Vânia Ferraz, Vera Neves, Joel Correia, Telma Amorim, Helena Pereira, Elsa S Santos, Leonino S Reis, Ana S Rombo, João Fernandes, Jorge C Freire, Ana Francisco, Irene Louro, Mª Clarisse Lopes, Saudade Oliveira, Ana P Gordo, Sara Queirós, Paulo Rodrigues, Teresa Lobão, Catarina Moura, Cynthia B Dreyer, Laysa C Meneghetti, Vanize Cabral, Priscila P Pinto, Francisca Esteves, Mª Raquel Galvão, Sofia Tytgat, Ite Casas-Novas, Mónica Bernardo, Helena Sousa, Gracinda Sousa, Ana P Belo, Pedro Martins, Fátima Pulido-Fuentes, Montserrat Cabral, Gil Prado, Alessandro Carvalho, Yara M Campos, Maria Moreira, Liliana Ferreira, José Teixeira, Ana Journal Article BMC Health Serv Res. 2016 Jul 6;16 Suppl 3(Suppl 3):200. doi: 10.1186/s12913-016-1423-5. PY - 2016 SN - 1472-6963 SP - 200 ST - Proceedings of the 3rd IPLeiria's International Health Congress : Leiria, Portugal. 6-7 May 2016 T2 - BMC Health Serv Res TI - Proceedings of the 3rd IPLeiria's International Health Congress : Leiria, Portugal. 6-7 May 2016 VL - 16 Suppl 3 ID - 3577 ER - TY - JOUR AB - This pilot study evaluated the effect of computer animated relaxation therapy in children between 7 and 13 years with tension-type headache and the children's experiences with the therapy. The therapy consisted of an uncontrolled nine-session course in modified progressive relaxation therapy assisted by computer animated surface EMG provided from the trapezius muscles and with the physiotherapist as a participant observer. Outcome measures were (a) headache frequency and intensity, (b) pericranial tenderness, (c) tension patterns, and (d) evaluations assessed at baseline and at 3 months follow up. Nine children, mean age 10.9 (SD 1.7) years, diagnosed with frequent episodic or chronic tension-type headache completed the course. The results showed a mean improvement of 45% for headache frequency at 3 months follow up versus baseline and a significant reduction in headache frequency for all participants and in Total Tenderness Score for children with frequent episodic tension-type headache. The children expressed a growing understanding of body reactions and an acquired ability to deactivate and regulate these reactions. Computer animated SEMG seems an applicable learning strategy for young headache sufferers. This study suggests that children below the age of 13 need both the dialog and guidance from a participant observer in order to achieve body awareness. AN - WOS:000303876500005 AU - Tornoe, B. AU - Skov, L. DA - Mar DO - 10.1007/s10484-011-9173-y IS - 1 N1 - Tornoe, Birte Skov, Liselotte Skov, Liselotte/0000-0002-2137-0735 1573-3270 PY - 2012 SN - 1090-0586 SP - 35-44 ST - Computer Animated Relaxation Therapy in Children Between 7 and 13 Years with Tension-Type Headache: A Pilot Study T2 - Applied Psychophysiology and Biofeedback TI - Computer Animated Relaxation Therapy in Children Between 7 and 13 Years with Tension-Type Headache: A Pilot Study UR - ://WOS:000303876500005 VL - 37 ID - 2446 ER - TY - JOUR AB - OBJECTIVE: The studies about autonomic nervous system (ANS) disorders in adult migraineurs show conflicting results with limited data on ANS function in childhood and adolescence. This study aimed to investigate ANS function in childhood migraine. PATIENTS AND METHODS: The migraine and control groups consisted of 35 migraineurs and 30 healthy children, respectively. In both groups, heart rate interval variation (RRIV) and sympathetic skin response (SSR) were used as noninvasive ANS function tests. RESULTS: No significant differences in age and gender distribution were found between the study and control groups. A family history of migraine was seen in 65% patients in the study group and 20% in the control group. The duration, quality, frequency, and location of pain were variable; only 14.1% of the patients had sensory and visual aural symptoms. There was neither a significant difference in RRIV and SSR between migraine and control groups (p > 0.05) nor in heart rate responses to deep breathing (p = 0.83). The mean amplitude of SSR in children with migraine was smaller than that in the control group, but it did not reach a level of statistical significance. CONCLUSIONS: In children with migraine, our results demonstrate no abnormal ANS function related to either the sympathetic or the parasympathetic nervous system. AD - Department of Pediatrics, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey. AN - 23771848 AU - Torun, E. AU - Gursoy, E. AU - Guler, S. AU - Kolukisa, M. AU - Tatli, B. DA - Oct DO - 10.1055/s-0033-1347934 DP - NLM ET - 2013/06/19 IS - 5 KW - Adolescent Autonomic Nervous System/physiopathology Autonomic Nervous System Diseases/*complications Child Female Galvanic Skin Response/physiology Heart Rate/*physiology Humans Male Migraine Disorders/complications/*diagnosis/physiopathology Reaction Time/physiology LA - eng N1 - 1439-1899 Torun, Emel Gursoy, Esra Guler, Serhat Kolukisa, Mehmet Tatli, Burak Journal Article Randomized Controlled Trial Germany Neuropediatrics. 2013 Oct;44(5):252-6. doi: 10.1055/s-0033-1347934. Epub 2013 Jun 14. PY - 2013 SN - 0174-304x SP - 252-6 ST - Characteristic features of migraine in schoolchildren and adolescents and its relationship with autonomic nervous system disorders T2 - Neuropediatrics TI - Characteristic features of migraine in schoolchildren and adolescents and its relationship with autonomic nervous system disorders VL - 44 ID - 3171 ER - TY - JOUR AB - Television viewing and its effect on physical health of schoolage children. Obesity is an increasing health problem all over the world. In addition to genetic and many environmental factors, television is also thought to be a risk factor. This study examined the effects of television viewing on obesity and other physical complaints among Turkish children. From two different socioeconomic class primary schools, 886 second- and third-grade children were visited at their schools, and their weight, height and triceps skin fold thickness (TST) were measured and body mass index (BMI) calculated. Television viewing behavior of the children, parental weight and height, and physical complaints of children were investigated by a questionnaire sent to parents. A subgroup of children was also called to the hospital, and their blood lipid profile and visual acuity were measured. According to the questionnaires, children were found to watch television 2.1 +/- 1.2 hours/day (hr/d) during the weekdays, 3.4 +/- 2.1 hr/d at the weekend and 2.5 +/- 1.3 hr/d generally. Children were also grouped according to the amount of time they watch television. Group 1 (n = 298) children watched television less than 2 hr/d, Group 2 (n = 323) watched 2-4 hr/d, and Group 3 (n = 68) more than 4 hr/d. The prevalence of obesity was 10.9% according to BMI, 11.8% according to TST and 6.4% according to both criteria. Obese girls were found to watch television longer than their peers (2.9 +/- 1.2 hr/d vs 2.3 +/- 1.3 hr/d, respectively, p = 0.034), but no other relation was found between television viewing and obesity. Headache, back pain, eye symptoms and sleep problems were found to be more often among children who watched television longer (p < 0.05). It was concluded that television viewing is related to many physical complaints, which may have lifelong consequences (obesity). Thus, pediatricians should give appropriate guidance to families about television habits and health consequences. AN - WOS:000178859700002 AU - Toyran, M. AU - Ozmert, E. AU - Yurdakok, K. DA - Jul-Sep IS - 3 N1 - Toyran, M Ozmert, E Yurdakok, K Toyran, Muge/AAC-2275-2020 Yurdakok, Kadriye/0000-0003-3672-3115 PY - 2002 SN - 0041-4301 SP - 194-203 ST - Television viewing and its effect on physical health of schoolage children T2 - Turkish Journal of Pediatrics TI - Television viewing and its effect on physical health of schoolage children UR - ://WOS:000178859700002 VL - 44 ID - 2829 ER - TY - JOUR AB - Research in adult populations indicates that several sociodemographic and environmental variables increase risk for pain and poor outcomes. There is little research exploring the impact of household income, health insurance coverage, barriers to health care, neighborhood and school safety, violence experienced, and neighborhood isolation on pediatric chronic pain. Data from the Add Health Study, a longitudinal examination of a nationally-representative adolescent sample were analyzed. The relationships between demographic variables, risk factors, chronic pain, and long-term health outcomes were examined. Adolescents with chronic pain had lower income, more health care barriers, greater safety concerns, and experienced more violence compared to those without pain. In a model together, female sex, White race/ethnicity, and greater health care barriers, safety concerns, and violence exposure conferred significant risk for chronic pain. Additional analyses revealed nuances in the strength of risk factors between racial/ethnic groups. Systemic health care barriers were significantly associated with chronic pain and may delay symptom alleviation and return to functioning. Considering access to care is necessary in prevention efforts. Among adolescents with chronic pain, greater safety concerns predicted poor mental health outcomes, particularly for White females. The cumulative stress of environmental concerns, such as safety, and managing chronic pain may worsen functioning. Perspective: Adolescents with chronic pain had lower income, and more health care barriers, safety concerns, and violence exposure compared to those without chronic pain. Access to care is a significant problem in youth with chronic pain. The relationships between race/ethnicity, risk factors, and health outcomes are complex and require additional research. (C) 2020 U.S. Association for the Study of Pain. Published by Elsevier Inc. All rights reserved. AN - WOS:000553361300014 AU - Tran, S. T. AU - Koven, M. L. AU - Castro, A. S. AU - Arce, A. B. G. AU - Carter, J. S. DA - Jan-Feb DO - 10.1016/j.jpain.2019.06.007 IS - 1-2 N1 - Tran, Susan T. Koven, Marissa L. Castro, Ashley S. Arce, Ana B. Goya Carter, Jocelyn S. Tran, Susan/0000-0001-5501-6825; Castro, Ashley/0000-0001-7266-0153 PY - 2020 SN - 1526-5900 SP - 170-181 ST - Sociodemographic and Environmental Factors are Associated with Adolescents' Pain and Longitudinal Health Outcomes T2 - Journal of Pain TI - Sociodemographic and Environmental Factors are Associated with Adolescents' Pain and Longitudinal Health Outcomes UR - ://WOS:000553361300014 VL - 21 ID - 1854 ER - TY - JOUR AB - Background: Previous studies of healthy children have indicated a link between autonomic nervous system (ANS) reactivity and health outcomes, but there is limited research on whether ANS reactivity is similar for children with chronic conditions. Objective: The aim of this study was to determine if ANS reactivity differs for children with sickle cell disease (SCD) compared with a community sample of children without SCD. Method: In two cross-sectional, descriptive studies, 32 public school children without chronic health problems were compared with 33 children with SCD. The children were 5-8 years old and they completed standardized protocols measuring ANS responses (respiratory sinus arrhythmia and preejection period) during rest and challenge conditions in social, cognitive, sensory, and emotion domains. Reactivity was calculated as the difference between challenge response minus rest for each domain and overall. Results: There were differences in the distributions of the samples in parent education and child age, so these variables were adjusted for in subsequent analyses. The community sample showed parasympathetic withdrawal (low respiratory sinus arrhythmia scores) and greater parasympathetic reactivity (low respiratory sinus arrhythmia difference scores and percentage of negative scores) compared with the children with SCD in the social (p<.05) and sensory (p<.05) domains. The children with SCD showed greater sympathetic reactivity (low preejection period difference scores) compared with the community children in the cognitive domain (p<.05), and a greater percentage of children with SCD versus the community children showed negative preejection period difference scores (sympathetic reactivity) in the social domain (p<.05). The community sample, but not the children with SCD, showed changes in respiratory sinus arrhythmia across domains (p<.05). Discussion: Children with SCD may display a different pattern of ANS responses to laboratory challenges compared with children without SCD from the same community. AN - WOS:000290201400007 AU - Treadwell, M. J. AU - Alkon, A. AU - Styles, L. AU - Boyce, W. T. DA - May-Jun DO - 10.1097/NNR.0b013e3182186a21 IS - 3 N1 - Treadwell, Marsha J. Alkon, Abbey Styles, Lori Boyce, W. Thomas 1538-9847 PY - 2011 SN - 0029-6562 SP - 197-207 ST - Autonomic Nervous System Reactivity Children With and Without Sickle Cell Disease T2 - Nursing Research TI - Autonomic Nervous System Reactivity Children With and Without Sickle Cell Disease UR - ://WOS:000290201400007 VL - 60 ID - 2494 ER - TY - JOUR AB - This study examined the relations between attachment styles and pain severity/depression in adolescents. Analyses examined whether anxiety and the 3 dimensions of pain catastrophizing mediated the associations between attachment styles, pain severity and depression. A total of 382 high-school students completed questionnaires assessing attachment styles, catastrophizing, depression, anxiety and, for those who reported pain during the last month, pain severity. Results revealed that secure attachment was associated with lower levels of pain severity, depression, pain catastrophizing and anxiety. Preoccupied and fearful attachment styles were associated with heightened pain severity, depression, pain catastrophizing and anxiety. Dismissing attachment style was only associated with high levels of depression and anxiety. Regression analyses revealed that anxiety and the helplessness dimension of pain catastrophizing mediated the relations between secure, preoccupied and fearful attachment styles and pain severity. Moreover, anxiety and the rumination dimension of pain catastrophizing mediated the relation between secure, preoccupied and fearful attachment styles and depression. These findings suggest that anxiety, pain catastrophizing and attachment styles are related processes but nevertheless make independent contributions to the prediction of pain severity and depression. In addition, these findings suggest that attachment styles and cognitive-affective factors might increase the risk of problematic outcomes in adolescents with pain conditions. Theoretical and clinical implications of these results are discussed. Perspective: The results of this study revealed that anxiety and the helplessness dimension of pain catastrophizing mediated the relation between attachment and pain severity whereas anxiety and rumination mediated the relation between attachment and depression. Attachment style and cognitive-affective factors might increase vulnerability for problematic pain outcomes in adolescents. (C) 2010 by the American Pain Society AN - WOS:000277092000007 AU - Tremblay, I. AU - Sullivan, M. J. L. DA - Feb DO - 10.1016/j.jpain.2009.06.015 IS - 2 N1 - Tremblay, Isabelle Sullivan, Michael J. L. PY - 2010 SN - 1526-5900 SP - 160-171 ST - Attachment and Pain Outcomes in Adolescents: The Mediating Role of Pain Catastrophizing and Anxiety T2 - Journal of Pain TI - Attachment and Pain Outcomes in Adolescents: The Mediating Role of Pain Catastrophizing and Anxiety UR - ://WOS:000277092000007 VL - 11 ID - 2567 ER - TY - JOUR AB - BACKGROUND: Somatization symptoms are a clinical reality in our environment. However, many pediatricians have little information about this condition or experience of its management. OBJECTIVE: To determine the clinical and differential characteristics of these patients. The early identification of these patients and initiation of therapy in the initial stages of the process would improve prognosis. MATERIAL AND METHOD: A retrospective review was performed of the children admitted to the short-stay unit of a tertiary hospital because of somatic complaints and whose final diagnosis was that of a somatization disorder. RESULTS: Sixty medical records were analyzed, of which 38 (63 %) corresponded to girls, with a mean age of 11 years at presentation. The most frequent reasons for consultation were related to the digestive and neurological systems. Thirty-four patients (57 %) had previously consulted for the same reason. In the sample analyzed, the most frequent personality trait was anxiety. The main triggers were familial and school factors. The most frequent diagnosis was pain disorder in 42 children (70 %). All patients received psychotherapy and 39 received complementary pharmacological treatment. CONCLUSIONS: The data analyzed in this study indicate that somatization symptoms most frequently occur in anxious, prepubescent girls, with migraine or non-specific abdominal pain of approximately one month's duration. Patients have usually made several previous visits and no organic causes are discovered on physical examination. AD - Sección de Urgencias. Servicio de Pediatría. Unidad Integrada Hospital Sant Joan de Déu-Hospital Clínic. Universidad de Barcelona. España. AN - 12628116 AU - Trenchs Sáinz de la Maza, V. AU - Hernández Bou, S. AU - Carballo Ruano, E. AU - García García, J. J. AU - Macià Rieradevall, E. AU - Alda Díez, J. A. AU - Luaces Cubells, C. DA - Jan DP - NLM ET - 2003/03/12 IS - 1 KW - Adolescent Child Child, Preschool Female Humans Male Retrospective Studies Somatoform Disorders/*diagnosis LA - spa N1 - Trenchs Sáinz de la Maza, V Hernández Bou, S Carballo Ruano, E García García, J J Macià Rieradevall, E Alda Díez, J A Luaces Cubells, C English Abstract Journal Article Spain An Pediatr (Barc). 2003 Jan;58(1):34-8. OP - Trastornos somatomorfos: una entidad emergente en pediatría. PY - 2003 SN - 1695-4033 (Print) 1695-4033 SP - 34-8 ST - [Somatization symptoms. An emerging pediatric entity] T2 - An Pediatr (Barc) TI - [Somatization symptoms. An emerging pediatric entity] VL - 58 ID - 3775 ER - TY - JOUR AB - Back pain is now recognised to occur early in childhood and is associated with high prevalence rates when estimated by survey. This review paper considers the risk factors associated with back pain in children aged 11-14 years, and particularly those present in a school setting. The risk factors most significantly associated with back pain are primarily characteristics of the individual with less strong associations with factors present in the school environment. The majority of intervention studies undertaken in a school setting have focussed on the effect of school furniture On posture and comfort and were of short-term duration. There is a need for further research in order to achieve a better understanding of the risk factors present in a school environment and to address ways to reduce the Currently recognised perceived problem of back pain among school children. A strategy for an evidence-based longitudinal intervention Study is proposed, with the content outlined under the headings: policy, school equipment and furniture, individual and family. (c) 2005 Elsevier Ltd. All rights reserved. AN - WOS:000233473300005 AU - Trevelyan, F. C. AU - Legg, S. J. DA - Jan DO - 10.1016/j.apergo.2004.02.008 IS - 1 N1 - Trevelyan, FC Legg, SJ 1872-9126 PY - 2006 SN - 0003-6870 SP - 45-54 ST - Back pain in school children - Where to from here? T2 - Applied Ergonomics TI - Back pain in school children - Where to from here? UR - ://WOS:000233473300005 VL - 37 ID - 2744 ER - TY - JOUR AB - Eight hundred and two subjects employed in N.W. England have been interviewed and examined after episodes of back or sciatic pain, using a standardized procedure. Data on recurrence of symptoms leading to further treatment or absence from work in the following two 12-month periods were obtained by postal questionary. Residual pain in the leg and a number of positive clinical signs of return to work, longer sickness--absence for the current attack, and two or more previous attacks were all associated with recurrence or persistence of symptoms. The prognosis also varied according to the cause of back pain, falls being associated not only with longer periods of absence in the current attack but with a higher rate of recurrence. The results have underlined the significance of a thorough examination on return to work after back pain for the industrial medical officer, as well as the epidemiological importance of this phase in the natural history of back and sciatic pain. AN - 6451938 AU - Troup, J. D. AU - Martin, J. W. AU - Lloyd, D. C. DA - Jan-Feb DO - 10.1097/00007632-198101000-00014 DP - NLM ET - 1981/01/01 IS - 1 KW - Absenteeism Adolescent Adult Aged *Back Pain/physiopathology Female Humans Male Middle Aged *Occupational Diseases/physiopathology Prospective Studies Recurrence LA - eng N1 - Troup, J D Martin, J W Lloyd, D C Journal Article Research Support, Non-U.S. Gov't United States Spine (Phila Pa 1976). 1981 Jan-Feb;6(1):61-9. doi: 10.1097/00007632-198101000-00014. PY - 1981 SN - 0362-2436 (Print) 0362-2436 SP - 61-9 ST - Back pain in industry. A prospective survey T2 - Spine (Phila Pa 1976) TI - Back pain in industry. A prospective survey VL - 6 ID - 3439 ER - TY - JOUR AB - Objectives. To study the prevalence of back pain and spinal alignment abnormalities in children aged 10 to 14 years; to define subsets of subjects with similar clinical profiles; and to identify factors associated with pain in the thoracic or lumbar spine. Patients and methods. 972 five- and nine-graders completed a back pain questionnaire at school and were examined by a school physician for spinal alignment abnormalities and for motion range limitation in the spine and/or lower limbs. Multivariate analysis was used to define clinical subsets and to identify factors associated with back pain. Results. The point prevalence of back pain increased with age. from 14.3% in the ten-year-olds to 24% in the 14-year-olds. Girls were more likely than boys to report back pain, which was usually located in the low back. The prevalence of scoliosis increased with age and was higher in the girls. Multivariate analysis identified five clinical profiles: no spinal pain; nonserious spinal pain with no impact on medical service utilization or physical activities; spinal pain unrelated to an injury: injury-related spinal pain not treated by drugs or physical therapy; and injury-related spinal pain treated by drugs and physical therapy. Several factors associated with spinal pain were identified. with variations across the five groups. AN - WOS:000082854200003 AU - Troussier, B. AU - Marchou-Lopez, S. AU - Pironneau, S. AU - Alais, E. AU - Grison, J. AU - Prel, G. AU - Pequegnot, C. AU - Degaudemaris, R. AU - Phelip, X. DA - Jul-Sep IS - 7-9 N1 - Troussier, B Marchou-Lopez, S Pironneau, S Alais, E Grison, J Prel, G Pequegnot, C Degaudemaris, R Phelip, X PY - 1999 SN - 1169-8446 SP - 370-380 ST - Back pain and spinal alignment abnormalities in schoolchildren T2 - Revue Du Rhumatisme TI - Back pain and spinal alignment abnormalities in schoolchildren UR - ://WOS:000082854200003 VL - 66 ID - 2881 ER - TY - JOUR AB - Background: This study examined relationships between adiposity, physical functioning, and physical activity. Methods: Obese (N = 107) and healthy-weight (N = 132) children aged 10-13 years underwent assessments of percent body fat (%BF, dual energy X-ray absorptiometry); knee extensor strength (KE, isokinetic dynamometry); cardiorespiratory fitness (CRF, peak oxygen uptake by cycle ergometry); physical health-related quality of life (HRQOL); and worst pain intensity and walking capacity [six-minute walk (6MWT)]. Structural equation modelling was used to assess relationships between variables. Results: Moderate relationships were observed between %BF and (1) 6MWT, (2) KE strength corrected for mass, and (3) CRF relative to mass (r -0.36 to -0.69, p <= 0.007). Weak relationships were found between %BF and physical HRQOL (r -0.27, p = 0.008); CRF relative to mass and physical HRQOL (r -0.24, p = 0.003); physical activity and 6MWT (r 0.17, p = 0.004). Squared multiple correlations showed that 29.6% variance in physical HRQOL was explained by %BF, pain, and CRF relative to mass; while 28.0% variance in 6MWT was explained by %BF and physical activity. Conclusions: It appears that children with a higher body fat percentage have poorer KE strength, CRF, and overall physical functioning. Reducing percent fat appears to be the best target to improve functioning. However, a combined approach to intervention, targeting reductions in body fat percentage, reductions in pain, and improvements in physical activity and CRF may assist physical functioning. AN - WOS:000372932700006 AU - Tsiros, M. D. AU - Buckley, J. D. AU - Olds, T. AU - Howe, P. R. C. AU - Hills, A. P. AU - Walkley, J. AU - Wood, R. AU - Kagawa, M. AU - Shield, A. AU - Taylor, L. AU - Shultz, S. P. AU - Grimshaw, P. N. AU - Grigg, K. AU - Coates, A. M. DA - Apr DO - 10.1089/chi.2015.0123 IS - 2 N1 - Tsiros, Margarita D. Buckley, Jonathan D. Olds, Timothy Howe, Peter R. C. Hills, Andrew P. Walkley, Jeff Wood, Rachel Kagawa, Masaharu Shield, Anthony Taylor, Lara Shultz, Sarah P. Grimshaw, Paul N. Grigg, Kaine Coates, Alison M. Olds, Tim/A-1223-2008; Howe, Peter/A-5006-2008; Howe, Peter/AAM-4972-2021; Grimshaw, Paul N/E-7695-2018; Hills, Andrew P/ABE-6408-2020; Coates, Alison M/A-3988-2009; Tsiros, Margarita/F-4205-2013; Kagawa, Masaharu/H-4326-2019 Olds, Tim/0000-0001-6894-5519; Howe, Peter/0000-0001-6546-7742; Howe, Peter/0000-0001-6546-7742; Grimshaw, Paul N/0000-0002-3359-1375; Hills, Andrew P/0000-0002-7787-7201; Coates, Alison M/0000-0003-1031-2545; Tsiros, Margarita/0000-0001-5359-3776; Kagawa, Masaharu/0000-0002-3842-7160; Buckley, Jonathan/0000-0003-0298-2186; Wood, Rachel/0000-0003-0208-6330; Wood, Rachel/0000-0001-7053-6319; Shield, Anthony/0000-0002-0393-2466 2153-2176 PY - 2016 SN - 2153-2168 SP - 126-134 ST - Impaired Physical Function Associated with Childhood Obesity: How Should We Intervene? T2 - Childhood Obesity TI - Impaired Physical Function Associated with Childhood Obesity: How Should We Intervene? UR - ://WOS:000372932700006 VL - 12 ID - 2174 ER - TY - JOUR AB - Educating the general public about chronic pain and its care is a national health priority. We evaluated knowledge, attitudes, and beliefs (KAB) of a 5-state, population-based sample of Hispanic individuals aged 35 to 75 years without chronic pain, representing more than 8.8 million persons. A Web-based survey assessed KAB using an adapted version of the Survey of Pain Attitudes-Brief and self-reported knowledge about chronic pain (nothing, a little, a lot). In unweighted analyses of participants (N = 349), the mean age was 52.0 (±10.6) years, 54% were women, 53% preferred Spanish, and 39% did not graduate from high school. More participants reported knowing nothing about chronic pain (24%) than a lot (12%). In weighted logistic models with knowing nothing as the reference, knowing a lot was associated with greater KAB for chronic pain-related emotions, functioning, and cure (all P < .01) but poorer KAB about pain medications (P < .001). Associations were similar for those knowing a little. Men and women preferring Spanish had poorer KAB about pain medications than men preferring English (both P < .001). In view of Hispanic individuals' disparities in chronic pain care, these data underscore the need for effective public educational campaigns about chronic pain. PERSPECTIVE: In this 5-state representative sample of Hispanic individuals without chronic pain, one-quarter reported knowing nothing about chronic pain and had poorer KAB about multiple aspects of this disease. This study reinforces the need to evaluate and address gaps in the general public's knowledge about chronic pain. AD - Department of Medicine, University of Texas Health San Antonio, San Antonio, Texas; Center for Research to Advance Community Health (ReACH), University of Texas Health San Antonio, San Antonio, Texas. Electronic address: turner@uthscsa.edu. Center for Research to Advance Community Health (ReACH), University of Texas Health San Antonio, San Antonio, Texas; Department of Epidemiology and Biostatistics, University of Texas Health San Antonio, San Antonio, Texas. Center for Research to Advance Community Health (ReACH), University of Texas Health San Antonio, San Antonio, Texas. Center for Research to Advance Community Health (ReACH), University of Texas Health San Antonio, San Antonio, Texas; Department of Health Promotion and Behavioral Science, University of Texas School of Public Health in San Antonio, San Antonio, Texas. Department of Psychiatry, University of Texas Health San Antonio, San Antonio, Texas. Center for Research to Advance Community Health (ReACH), University of Texas Health San Antonio, San Antonio, Texas; South Central Area Health Education Center, University of Texas Health San Antonio, San Antonio, Texas. AN - 28088505 AU - Turner, B. J. AU - Liang, Y. AU - Rodriguez, N. AU - Valerio, M. A. AU - Rochat, A. AU - Potter, J. S. AU - Winkler, P. C2 - PMC6023619 C6 - HRAMS965039 DA - Jun DO - 10.1016/j.jpain.2016.12.019 DP - NLM ET - 2017/01/16 IS - 6 KW - Adult Aged Chronic Pain/*etiology Female Health Knowledge, Attitudes, Practice/*ethnology Hispanic Americans/*psychology Humans Male Middle Aged Pain Management Regression Analysis Self Report Socioeconomic Factors United States Chronic pain Hispanic knowledge attitudes beliefs representative sample LA - eng N1 - 1528-8447 Turner, Barbara J Liang, Yuanyuan Rodriguez, Natalia Valerio, Melissa A Rochat, Andrea Potter, Jennifer S Winkler, Paula ME-1303-5729/Patient-Centered Outcomes Research Institute/United States ME-1303-5729/Patient-Centered Outcomes Research Institute/ Journal Article J Pain. 2017 Jun;18(6):628-636. doi: 10.1016/j.jpain.2016.12.019. Epub 2017 Jan 12. PY - 2017 SN - 1526-5900 (Print) 1526-5900 SP - 628-636 ST - Gaps in the Public's Knowledge About Chronic Pain: Representative Sample of Hispanic Residents From 5 States T2 - J Pain TI - Gaps in the Public's Knowledge About Chronic Pain: Representative Sample of Hispanic Residents From 5 States VL - 18 ID - 3301 ER - TY - JOUR AB - Introduction Chronic pain, defined as persistent or recurring pain or pain lasting longer than 3 months, is a common childhood problem and can profoundly impact children's physical, psychological and social functioning. The last comprehensive systematic review estimating the prevalence of chronic pain in children and adolescents was published in 2011. Since then, the literature on paediatric chronic pain has grown substantially. This manuscript outlines a protocol for an updated systematic review to provide updated estimates of the prevalence of various forms of chronic pain in children and adolescence. The review will also examine the relationship between sociodemographic and psychosocial factors related to chronic pain prevalence. Methods and analysis This review will follow Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. We will search EMBASE, PubMed, CINAHL and PsycINFO for observational studies published in English between 2009 and 2020 reporting population-based estimates of chronic non-disease-related pain prevalence in children or adolescents (age <= 19 years). Two independent reviewers will screen the titles and abstracts retrieved from the search based on predefined eligibility criteria. The full texts of relevant studies will then be assessed by two reviewers. Studies meeting inclusion criteria will be categorised according to the type of pain investigated: headache only, abdominal pain only, back pain only, musculoskeletal pain, combined pain, general pain and other pain. Data will be extracted using customised forms and studies will be assessed for risk of bias using a 10-item tool developed by Hoy et al (2012). A narrative synthesis will summarise the prevalence estimates of paediatric chronic pain and associated sociodemographic and psychosocial correlates. Meta-analyses and meta-regressions will be performed if the data permit. Ethics and dissemination Ethical approval is not required. Findings will be disseminated through publication in an academic journal, presentations at conferences and in various media. PROSPERO registration number CRD42020198690. AN - WOS:000621082800017 AU - Tutelman, P. R. AU - Langley, C. L. AU - Chambers, C. T. AU - Parker, J. A. AU - Finley, G. A. AU - Chapman, D. AU - Jones, G. T. AU - Macfarlane, G. J. AU - Marianayagam, J. C7 - e043675 DO - 10.1136/bmjopen-2020-043675 IS - 2 N1 - Tutelman, Perri R. Langley, Charlotte L. Chambers, Christine T. Parker, Jennifer A. Finley, G. Allen Chapman, Darlene Jones, Gareth T. Macfarlane, Gary J. Marianayagam, Justina ; Macfarlane, Gary/I-9521-2014; Chambers, Christine/I-2811-2014 Finley, G. Allen/0000-0003-4579-7749; Jones, Gareth/0000-0003-0016-7591; Macfarlane, Gary/0000-0003-2322-3314; Chambers, Christine/0000-0002-7138-916X PY - 2021 SN - 2044-6055 ST - Epidemiology of chronic pain in children and adolescents: a protocol for a systematic review update T2 - Bmj Open TI - Epidemiology of chronic pain in children and adolescents: a protocol for a systematic review update UR - ://WOS:000621082800017 VL - 11 ID - 1769 ER - TY - JOUR AB - OBJECTIVE: To determine the prevalence of functional gastrointestinal disorders (FGIDs) in a primary care setting and to assess the usefulness of pediatric Rome criteria. METHODS: The Questionnaire on Pediatric Gastrointestinal Symptoms (QPGS) assessing the pediatric Rome criteria was administered to 243 school-age children visiting a general pediatric clinic for annual school physicals. Pearson chi statistics were used to determine the association of various demographic factors with FGIDs. RESULTS: All children were African American, 47.7% were girls, and the mean +/- standard deviation age of the group was 10.7 +/- 3.9 years. QPGS detected 52 children (21.4%) with FGID. Diagnoses included aerophagia (6), abdominal migraine (1), cyclic vomiting syndrome (2), functional dyspepsia (2), functional abdominal pain syndrome (1), functional constipation (39) and functional fecal retention (1). Thorough clinical evaluation identified 47 (19.3%) children with FGIDs. Five of the children (2.1%) identified as having FGID on QPGS were felt not to have FGID by the examining physician. Children with FGIDs were not different from healthy children in age, insurance, parent's education, employment or number of children in the family. FGIDs were more common in girls (29/47 girls, P = 0.028). Children with FGIDs tended to live in single-parent households and miss school more often than children without FGIDs (P = 0.08). CONCLUSIONS: Functional gastrointestinal disorders are common among African American children and adolescents in a primary care setting and predominantly affect girls. Symptom-based criteria are useful in the diagnosis of pediatric FGIDs. AD - Division of Pediatric Gastroenterology, Department of Pediatrics, University of Iowa, Carver College of Medicine, Iowa City, IA 52242, USA. aliye-uc@uiowa.edu AN - 16540795 AU - Uc, A. AU - Hyman, P. E. AU - Walker, L. S. C2 - PMC3232040 C6 - NIHMS338108 DA - Mar DO - 10.1097/01.mpg.0000189371.29911.68 DP - NLM ET - 2006/03/17 IS - 3 KW - Abdominal Pain/diagnosis/epidemiology Adolescent African Americans/*statistics & numerical data Child Child, Preschool Constipation/diagnosis/epidemiology Diagnosis, Differential Dyspepsia/diagnosis/epidemiology Female Gastrointestinal Diseases/*diagnosis/*epidemiology Humans Male Prevalence *Primary Health Care Severity of Illness Index Sex Factors Single-Parent Family Surveys and Questionnaires Vomiting/diagnosis/epidemiology LA - eng N1 - 1536-4801 Uc, Aliye Hyman, Paul E Walker, Lynn S R01 HD023264/HD/NICHD NIH HHS/United States R01 HD023264-18/HD/NICHD NIH HHS/United States Journal Article J Pediatr Gastroenterol Nutr. 2006 Mar;42(3):270-4. doi: 10.1097/01.mpg.0000189371.29911.68. PY - 2006 SN - 0277-2116 (Print) 0277-2116 SP - 270-4 ST - Functional gastrointestinal disorders in African American children in primary care T2 - J Pediatr Gastroenterol Nutr TI - Functional gastrointestinal disorders in African American children in primary care VL - 42 ID - 3804 ER - TY - JOUR AB - OBJECTIVES: To determine the prevalence, pattern, and predisposing factors of abdominal pain-predominant functional gastrointestinal disorders (AP-FGIDs) in adolescent Nigerians. METHODS: A cross-sectional study was conducted in 2 states in the southern part of Nigeria in June 2014. Adolescents of age 10 to 18 years were recruited from 11 secondary schools using a stratified random sampling technique. A validated self-administered questionnaire on Rome III criteria for diagnosing AP-FGIDs and its determinants were filled by the participants in a classroom setting. RESULTS: A total of 874 participants filled the questionnaire. Of this, 818 (93.4%) filled it properly and were included in the final analysis. The mean age of the participants was 14.6 ± 2.0 years with 409 (50.0%) being boys. AP-FGIDs were present in 81 (9.9%) participants. Forty six (5.6%) of the study participants had irritable bowel syndrome (IBS), 21 (2.6%) functional abdominal pain, 15 (1.8%) abdominal migraine while 3 (0.4%) had functional dyspepsia. The difference in AP-FGIDs between adolescents residing in rural and urban areas was not statistically significant (P = 0.22). Intestinal and extra-intestinal symptoms occurred more frequently in those with AP-FGIDs. Nausea was the only symptom independently associated with AP-FGIDs (p = 0.015). Multiple regression analysis showed no significant association between stressful life events and AP-FGIDs. CONCLUSIONS: AP-FGIDs are a significant health problem in Nigerian adolescents. In addition to the intestinal symptoms, most of the affected children and others also had extraintestinal symptoms. None of the stressful life events evaluated was significantly associated with FGIDs. AD - *Department of Paediatrics, University of Uyo Teaching Hospital, Uyo, Nigeria †Department of Physiology, Faculty of Medicine ‡Department of Paediatrics, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka §Department of Paediatrics, University of Calabar Teaching Hospital, Calabar, Nigeria ||Department of Paediatrics Gastroenterology and Nutrition, Emma Children's Hospital, Academic Medical Centre, Amsterdam, The Netherlands. AN - 26465793 AU - Udoh, E. AU - Devanarayana, N. M. AU - Rajindrajith, S. AU - Meremikwu, M. AU - Benninga, M. A. DA - Apr DO - 10.1097/mpg.0000000000000994 DP - NLM ET - 2015/10/16 IS - 4 KW - Abdominal Pain/*etiology Adolescent Age Factors Child Cross-Sectional Studies Dyspepsia/diagnosis/epidemiology/physiopathology Female Gastrointestinal Diseases/diagnosis/epidemiology/*physiopathology Gastrointestinal Tract/*physiopathology Humans Irritable Bowel Syndrome/diagnosis/epidemiology/physiopathology Logistic Models Male Migraine Disorders/diagnosis/epidemiology/physiopathology Nausea/etiology Nigeria/epidemiology Pain Measurement Prevalence Risk Factors Rural Health Self Report Urban Health LA - eng N1 - 1536-4801 Udoh, Ekong Devanarayana, Niranga Manjuri Rajindrajith, Shaman Meremikwu, Martin Benninga, Marc Alexander Journal Article United States J Pediatr Gastroenterol Nutr. 2016 Apr;62(4):588-93. doi: 10.1097/MPG.0000000000000994. PY - 2016 SN - 0277-2116 SP - 588-93 ST - Abdominal Pain-predominant Functional Gastrointestinal Disorders in Adolescent Nigerians T2 - J Pediatr Gastroenterol Nutr TI - Abdominal Pain-predominant Functional Gastrointestinal Disorders in Adolescent Nigerians VL - 62 ID - 3552 ER - TY - JOUR AB - OBJECTIVE: Human papillomavirus (HPV) vaccination has proven to be effective for prevention of HPV infection and HPV-associated precancerous cervical lesions.(1) However, HPV vaccination rates have remained flat, and whether or not to vaccinate has become a social issue. In the United States in 2013, HPV vaccine coverage for girls ages 13-17 years was only 57%.(2) A notable inhibitory factor to getting vaccinated has been reports of possible adverse effects. Safety concerns among US parents have increased (4.5% in 2008 to 16.4% in 2010), as have intentions not to vaccinate their daughters against HPV (39.8% in 2008 to 43.9% in 2010; odds ratio for trend, 1.08; 95% confidence interval, 1.04-1.13).(3) STUDY DESIGN: In Japan, financial support of the government was initiated from 2011, and recommendation was initiated in April 2013. However, Japan has failed to capitalize on the HPV vaccine's potential for cervical cancer prevention. Japanese media reports in May and June 2013 concerning the vaccine's potential for adverse effects including complex regional pain syndrome and suspension of the government's recommendation for the vaccination on June 14, 2013, have led to public distrust and a dramatic decrease in HPV vaccination rates.(4) To demonstrate the depth of the problem, we analyzed the HPV vaccine coverage for 7th-grade girls in Sakai, Japan. We looked at those who had initiated their 3-dosage series either before or after the negative media reports ran. Girls from 7-11th grade were vaccination targets, with vaccinations at the 7th-grade level being the most desirable. RESULTS: The first trimester of the Japanese school year runs from April 1 through late July; the summer break is about 6 weeks. The adverse Japanese media reports and the Ministry of Health, Labor, and Welfare suspension announcement occurred about 40 days prior to summer vacation, during which the girls in Sakai were expected to go to a clinic for HPV vaccination. During the summer vacation period of 2012, nearly half of the 7th-grade girls got an inoculation. However, in 2013, the number of girls vaccinated in May began to decrease following the news reports, and by late June it was almost 0 (Figure, A). The vaccination rates of the 7-10th graders who had an opportunity for vaccination prior to the media reports were between 57.8-74.8% (2012). However, following the adverse reports, the rate plunged from 65.4% (2012) to 3.9% (2013) (incidence rate ratio, 0.060; 95% confidence interval, 0.051-0.071) (Figure, B). The girls received HPV vaccination mostly in the 7th grade. The rate of the number of those vaccinated in 7th grade was 70.4% (7th grade: 2632; and 8-10th grade: 1105) in 2012. In 2013, not only the number of those vaccinated in 7th grade but also those in 8-10th grades decreased significantly (7th grade: 158; and 8-10th grade: 90). CONCLUSION: Improved education around the critical importance of HPV vaccine and screening for cervical cancer prevention is needed worldwide. AN - WOS:000350377500048 AU - Ueda, Y. AU - Enomoto, T. AU - Sekine, M. AU - Egawa-Takata, T. AU - Morimoto, A. AU - Kimura, T. DA - Mar DO - 10.1016/j.ajog.2014.11.037 IS - 3 N1 - Ueda, Yutaka Enomoto, Takayuki Sekine, Masayuki Egawa-Takata, Tomomi Morimoto, Akiko Kimura, Tadashi 1097-6868 PY - 2015 SN - 0002-9378 SP - 405-406 ST - Japan's failure to vaccinate girls against human papillomavirus T2 - American Journal of Obstetrics and Gynecology TI - Japan's failure to vaccinate girls against human papillomavirus UR - ://WOS:000350377500048 VL - 212 ID - 2248 ER - TY - JOUR AB - The objectives of this study were to determine the prevalence and characteristics of recurrent headaches and to investigate the sociodemographic differences between high school students with or without recurrent headaches from Izmir, Turkey. Multistep, stratified, cluster sampling method was used in this analytic, school-based cross-sectional study. Twenty-one schools were selected randomly, and 2384 preparatory, first-, second-, and third-grade high school students from 84 different classrooms constituted the study cohort. The prevalence of recurrent headaches was 45.7% (1090/ 2384). Female students had a significantly higher headache frequency than males (P = 0.000). No significant relationship was evident between age and headache (P = 0.065). Also, there were no significant differences between the adolescents with or without headache for variables such as parental divorce (P = 0.052), existence of a step parent (P = 0.32), people with whom the students live at home (P = 0.186), number of siblings (P = 0.37), and maternal and paternal educational levels (P = 0.62 and P = 0.15, respectively). Headache frequency was higher when the income level of the student's family was lower (P = 0.016). Among the students who had headaches, 53.3% had a medication, 37.3% were referred to a physician, and in 27.2% of them a diagnosis was established. School absenteeism with a ratio of 26.5% was a common problem among the students with headaches. These results indicate that approximately one half of Turkish high school students have recurrent headaches which reduce the quality of their lives. (c) 2006 by Elsevier Inc. All rights reserved. AN - WOS:000235417000005 AU - Unalp, A. AU - Dirik, E. AU - Kurul, S. DA - Feb DO - 10.1016/j.pediatrneurol.2005.08.001 IS - 2 N1 - Unalp, A Dirik, E Kurul, S Hiz, Semra/O-4943-2018 1873-5150 PY - 2006 SN - 0887-8994 SP - 110-115 ST - Prevalence and characteristics of recurrent headaches in Turkish adolescents T2 - Pediatric Neurology TI - Prevalence and characteristics of recurrent headaches in Turkish adolescents UR - ://WOS:000235417000005 VL - 34 ID - 2743 ER - TY - JOUR AB - BACKGROUND: The majority of previous studies on headache in children and adolescents have focused mainly on migraine. There is a paucity of population-based studies investigating the prevalence of tension-type headache (TTH). The objectives of the present study were to estimate the prevalence of migraine and TTH in adolescents using the 2004 International Headache Society (IHS) criteria and to determine the sociodemographic and clinical differences between the migraine and TTH. METHODS: Stratified group sampling was used in the present analytic, school-based, cross-sectional study. From the city of Izmir, 2384 students aged 14-18 years were invited to complete a questionnaire. RESULTS: Migraine was found to be more common than TTH (21.3% vs 5.1%). The prevalence increased considerably to 29.9 and 15%, respectively, when the criteria defining the number and duration of headaches were excluded. All types of headaches were more frequent in female subjects but no significant difference was found in gender between the headache groups (P= 0.073). Headache in temples, number of siblings (more than one sibling), mother's and father's education (at least high school graduation) were more commonly seen in students with TTH. Absenteeism rate due to the headache was found to be higher in the migraine group than in the TTH group (P= 0.000). CONCLUSIONS: Migraine and TTH were found to be common types of headaches in adolescents. It was thought that, with the use of modified IHS criteria, the number of undiagnosed patients with headache will decrease. AD - Department of Pediatric Neurology, Dokuz Eylül University Faculty of Medicine, Izmir, Turkey. aycanunalp@mynet.com AN - 18045302 AU - Unalp, A. AU - Dirik, E. AU - Kurul, S. DA - Dec DO - 10.1111/j.1442-200X.2007.02484.x DP - NLM ET - 2007/11/30 IS - 6 KW - Adolescent Cross-Sectional Studies Educational Status Family Characteristics Female Humans Male Migraine Disorders/*epidemiology Precipitating Factors Prevalence Sex Distribution Surveys and Questionnaires Tension-Type Headache/*epidemiology Turkey/epidemiology LA - eng N1 - Unalp, Aycan Dirik, Eray Kurul, Semra Journal Article Australia Pediatr Int. 2007 Dec;49(6):943-9. doi: 10.1111/j.1442-200X.2007.02484.x. PY - 2007 SN - 1328-8067 (Print) 1328-8067 SP - 943-9 ST - Prevalence and clinical findings of migraine and tension-type headache in adolescents T2 - Pediatr Int TI - Prevalence and clinical findings of migraine and tension-type headache in adolescents VL - 49 ID - 3641 ER - TY - JOUR AB - OBJECTIVES: To identify characteristics of randomized controlled trial participants which predict greater benefits from physical treatments for low back pain. If successful, this would allow more appropriate selection of patients for different treatments. METHODS: We did a secondary analysis of the UK Back pain Exercise And Manipulation trial (UK BEAM n = 1334) dataset to identify baseline characteristics predicting response to manipulation, exercise and manipulation followed by exercise (combined treatment). Rather than simply identifying factors associated with overall outcome, we tested for the statistical significance of the interaction between treatment allocation, baseline characteristics and outcome to identify factors that predicted response to treatment. We also did a post-hoc subgroup analysis to present separate results for trial participants with subacute and chronic low back pain to inform future evidence synthesis. RESULTS: Age, work status, age of leaving school, 'pain and disability', 'quality of life' and 'beliefs' at baseline all predicted overall outcome. None of these predicted response to treatment. In those allocated to combined treatment, there was a suggestion that expecting treatment to be helpful might improve outcome at 1 yr. Episode length at study entry did not predict response to treatment. CONCLUSION: Baseline participant characteristics did not predict response to the UK BEAM treatment packages. Using recognized prognostic variables to select patients for different treatment packages, without first demonstrating that these factors affect response to treatment, may be inappropriate. In particular, this analysis suggests that the distinction between subacute and chronic low back pain may not be useful when considering treatment choices. AD - Centre for Health Sciences, Barts and The London, Queen Mary's School of Medicine and Dentistry, Abernethy Building, 2 Newark Street, Whitechapel, London E1 2AT, UK. m.underwood@qmul.ac.uk AN - 17522096 AU - Underwood, M. R. AU - Morton, V. AU - Farrin, A. DA - Aug DO - 10.1093/rheumatology/kem113 DP - NLM ET - 2007/05/25 IS - 8 KW - Adolescent Adult Age Factors Exercise Therapy Humans Low Back Pain/psychology/*rehabilitation Manipulation, Spinal Middle Aged Pain Measurement/methods Patient Selection *Physical Therapy Modalities Prognosis Quality of Life Severity of Illness Index Time Factors Treatment Outcome LA - eng N1 - Underwood, M R Morton, V Farrin, A UK BEAM Trial Team Journal Article Multicenter Study Randomized Controlled Trial England Rheumatology (Oxford). 2007 Aug;46(8):1297-302. doi: 10.1093/rheumatology/kem113. Epub 2007 May 23. PY - 2007 SN - 1462-0324 (Print) 1462-0324 SP - 1297-302 ST - Do baseline characteristics predict response to treatment for low back pain? Secondary analysis of the UK BEAM dataset [ISRCTN32683578] T2 - Rheumatology (Oxford) TI - Do baseline characteristics predict response to treatment for low back pain? Secondary analysis of the UK BEAM dataset [ISRCTN32683578] VL - 46 ID - 4039 ER - TY - JOUR AB - Objective: To examine, in children, relationships between self-reported recurrent pain and emotion regulation indicated by rated internalizing and externalizing problem behaviors and adjustment. Method. Finnish 11-12-year-old schoolchildren (N = 414) completed a questionnaire measuring recurrent pain. Emotion regulation was assessed by a Multidimensional Peer Nomination Inventory, Teacher Rating Form. Relationships between recurrent pain and emotion regulation were examined in logistic regression analyses, after controlling for past injuries and chronic illnesses. Results: Independent of injuries and chronic illnesses, externalizing and internalizing problem behaviors related to recurrent pain, and more so together than separately. Gender differences were found; constructive behavior associated with recurrent pain only in girls. Conclusions. Low self-control of emotions, indicated by internalizing and externalizing problem behaviors, was related to pain in both boys and girls; high self-control of emotions, indicated by constructive behavior, associated with pain only in girls. AN - WOS:000174986300004 AU - Vaalamo, I. AU - Pulkkinen, L. AU - Kinnunen, T. AU - Kaprio, J. AU - Rose, R. J. DA - Apr-May DO - 10.1093/jpepsy/27.3.245 IS - 3 N1 - Vaalamo, I Pulkkinen, L Kinnunen, T Kaprio, J Rose, RJ Kaprio, Jaakko/A-1820-2008 Kaprio, Jaakko/0000-0002-3716-2455; Vaalamo, Inka/0000-0003-2612-5197; Pulkkinen, Lea/0000-0002-4290-6690 1465-735x PY - 2002 SN - 0146-8693 SP - 245-257 ST - Interactive effects of internalizing and externalizing problem behaviors on recurrent pain in children T2 - Journal of Pediatric Psychology TI - Interactive effects of internalizing and externalizing problem behaviors on recurrent pain in children UR - ://WOS:000174986300004 VL - 27 ID - 2834 ER - TY - JOUR AB - A questionnaire was sent to 967 schoolchildren, in two age groups, in northern Finland in order to investigate the prevalence of chronic knee pain. A response rate of 88.5% was achieved. Adolescents (aged 14-15 years) had significantly more knee pain (p < 0.0001) than children (aged 9-10 years). The total prevalence of chronic knee pain at the time of the evaluation was 18.5% among adolescents and 3.9% among children. There was no significant difference in the prevalence of chronic knee pain between boys and girls in these age groups. Overweight was not a predisposing factor in chronic knee pain. AN - WOS:A1995RJ49600019 AU - Vahasarja, V. DA - Jul DO - 10.1111/j.1651-2227.1995.tb13760.x IS - 7 N1 - Vahasarja, v 1651-2227 PY - 1995 SN - 0803-5253 SP - 803-805 ST - PREVALENCE OF CHRONIC KNEE PAIN IN CHILDREN AND ADOLESCENTS IN NORTHERN FINLAND T2 - Acta Paediatrica TI - PREVALENCE OF CHRONIC KNEE PAIN IN CHILDREN AND ADOLESCENTS IN NORTHERN FINLAND UR - ://WOS:A1995RJ49600019 VL - 84 ID - 2934 ER - TY - JOUR AB - Background: This study aimed to explore the prevalence of chronic specific-site and multisite pain in adolescents and to investigate how it can possibly be determined by school-related factors. Methods: A population-based cross-sectional study was conducted in 2014 in Lithuania as a Health Behavior in School-Aged Children (HBSC) survey. The sample consisted of 5730 school children, aged 11, 13, and 15 years. The analyzed data focused on the school-related context (relations with family, peers, and teachers; school demand, satisfaction, and bullying) of adolescents and subjective health complaints. The relationships between social support and health complaint variables were estimated using multivariate analyses. Results: The most common subjective health complaint among respondents was a headache. Backache, headache, and stomachache were more common among girls than boys. All somatic complaints were expressed more in younger ages. Multisite complaints were more common among girls and were associated with ageolder ones reported more complaints. School-related bullying, school demand, satisfaction, and social support were the most relevant and independent factors for multisite somatic complaints among adolescents. AN - WOS:000469517300102 AU - Vaiciunas, T. AU - Smigelskas, K. C7 - 1577 DA - May DO - 10.3390/ijerph16091577 IS - 9 N1 - Vaiciunas, Tomas Smigelskas, Kastytis Smigelskas, Kastytis/0000-0001-5371-9500 1660-4601 PY - 2019 SN - 1661-7827 ST - The Role of School-Related Well-Being for Adolescent Subjective Health Complaints T2 - International Journal of Environmental Research and Public Health TI - The Role of School-Related Well-Being for Adolescent Subjective Health Complaints UR - ://WOS:000469517300102 VL - 16 ID - 1924 ER - TY - JOUR AB - INTRODUCTION: Children born very preterm display altered pain thresholds. Little is known about the neonatal clinical and psychosocial factors associated with their later pain perception. OBJECTIVE: We aimed to examine whether the number of neonatal invasive procedures, adjusted for other clinical and psychosocial factors, was associated with self-ratings of pain during a blood collection procedure at school age in children born very preterm. MATERIALS AND METHODS: 56 children born very preterm (24 to 32 weeks gestational age), followed longitudinally from birth, and free of major neurodevelopmental impairments underwent a blood collection by venipuncture at age 7.5 years. The children's pain was self-reported using the Coloured Analog Scale and the Facial Affective Scale. Parents completed the Child Behavior Checklist and the State-Trait Anxiety Inventory. Pain exposure (the number of invasive procedures) and clinical factors from birth to term-equivalent age were obtained prospectively. Multiple linear regression was used to predict children's pain self-ratings from neonatal pain exposure after adjusting for neonatal clinical and concurrent psychosocial factors. RESULTS: A greater number of neonatal invasive procedures and higher parent trait-anxiety were associated with higher pain intensity ratings during venipuncture at age 7.5 years. Fewer surgeries and lower concurrent child externalizing behaviors were associated with a higher pain intensity. CONCLUSIONS: In very preterm children, exposure to neonatal pain was related to altered pain self-ratings at school age, independent of other neonatal factors. Neonatal surgeries and concurrent psychosocial factors were also associated with pain ratings. AU - Valeri, Beatriz O. AU - Ranger, Manon AU - Chau, Cecil M. Y. AU - Cepeda, Ivan L. AU - Synnes, Anne AU - Linhares, Maria Beatriz M. AU - Grunau, Ruth E. DA - 2016/12// DO - 10.1097/AJP.0000000000000353 DP - PubMed IS - 12 J2 - Clin J Pain KW - Anxiety Child Female Follow-Up Studies Humans Infant, Extremely Premature Infant, Newborn Intensive Care, Neonatal Linear Models Longitudinal Studies Male Pain Pain Management Pain Threshold Parents Phlebotomy Prospective Studies Self Report LA - eng PY - 2016 SN - 1536-5409 SP - 1086-1093 ST - Neonatal Invasive Procedures Predict Pain Intensity at School Age in Children Born Very Preterm T2 - The Clinical Journal of Pain TI - Neonatal Invasive Procedures Predict Pain Intensity at School Age in Children Born Very Preterm UR - http://www.ncbi.nlm.nih.gov/pubmed/26783986 VL - 32 ID - 84 ER - TY - JOUR AB - Noroviruses, along with Sapoviruses are human pathogenic representatives of the family Caliciviridae. They are widely distributed. Their high resistance in the external environment, their great content in feces and vomit, and the very low infective dose of 10-100 virus particles, explain their high ability to cause outbreaks of gastroenteritis. The transmission of the infection takes place by fecal-oral route. Initial clinical symptoms occur after an incubation period of between 6-48 h. The first symptoms to appear are nausea and abdominal pain followed by persistent vomiting and intense nonbloody diarrhea. The reverse - transcriptase polymerase chain reaction RT-PCR is the method of choice to set the diagnosis. As an alternative method ELISA could be used in order to search for a viral antigen in material from feces or vomit. After recovery has taken place partial immunity appears for a short time - about two months. Our aim was to analyse the major epidemiological, clinical and laboratory characteristics in the hospitalized patients with norovirus gastroenteritis. The study included a group of 22 students from the Vocational School of Computer Systems and Technology in Pravets, Bulgaria, who got momentarily ill with severe gastroenteritis. They had a mean age of 16 years, in the range of 14-18 years, 17 boys (77%) and 5 girls (23%). The beginning was acute with fever (in all subjects), 12 of them (54%) had low-grade fever (temperature up to 38 degrees C) and three patients were febrile. Vomiting was observed in all patients and in 17 (77%) it was accompanied by nausea. Abdominal pain was present in 11 patients (50%). Diarrhea was present in seven patients (31%). Microbiological diagnosis included examination of a fecal sample for intestinal pathogenic bacteria and viruses, and in nine (41%) patients norovirus infection was demonstrated by PCR. The therapeutic approach included oral and parenteral rehydration, symptomatic treatment and diet. The patients analysed developed second degree of dehydration and had a very good response to the treatment. It was performed within 24-72 h after admission. This indicates that it should be initiated as soon as possible with regards to any early complains. Infections with noroviruses should always be suspected in cases of gastroenteritis with group character on the basis of data of eating common food in closed groups. AN - WOS:000496718200006 AU - Valkov, T. K. AU - Strashimirov, D. T. AU - Donkov, G. O. AU - Yancheva, N. S. AU - Mitova-Mineva, Y. I. AU - Doycheva, V. C. AU - Kayrakova, B. G. AU - Tomova, II AU - Tiholova, M. M. AU - Chervenyakova, T. P. DO - 10.7546/crabs.2019.10.06 IS - 10 N1 - Valkov, Trifon K. Strashimirov, Dimitar T. Donkov, George O. Yancheva, Nina S. Mitova-Mineva, Yordanka I. Doycheva, Viktoriya C. Kayrakova, Bojidarka G. Tomova, Ivelina I. Tiholova, Mayda M. Chervenyakova, Tatyana P. PY - 2019 SN - 1310-1331 SP - 1343-1350 ST - CLINICAL AND EPIDEMIOLOGICAL INVESTIGATIONS OF AN OUTBREAK OF GASTROENTERITIS WITH NOROVIRUS ETIOLOGY IN PRAVETS, BULGARIA, MARCH 2016 T2 - Comptes Rendus De L Academie Bulgare Des Sciences TI - CLINICAL AND EPIDEMIOLOGICAL INVESTIGATIONS OF AN OUTBREAK OF GASTROENTERITIS WITH NOROVIRUS ETIOLOGY IN PRAVETS, BULGARIA, MARCH 2016 UR - ://WOS:000496718200006 VL - 72 ID - 1964 ER - TY - JOUR AB - Background Percutaneous laser disc decompression (PLDD) for patients with lumbar disc herniation is believed to be cheaper than surgery. However, cost-effectiveness has never been studied. Materials and Methods A cost utility analysis was performed alongside a randomized controlled trial comparing PLDD and conventional surgery. Patients reported their quality of life using the EuroQol five dimensions questionnaire (EQ-5D), 36-item short form health survey (SF-36 and derived SF-6D) and a visual analogue scale (VAS). Using cost diaries patients reported health care use, non-health care use and hours of absenteeism from work. The 1-year societal costs were compared with 1-year quality adjusted life years (QALYs) based on the United States (US) EQ-5D. Sensitivity analyses were carried out on the use of different utility measures (Netherland (NL) EQ-5D, SF-6D, or VAS) and on the perspective (societal or healthcare). Results On the US EQ-5D, conventional surgery provided a non-significant gain in QALYs of 0.033 (95% confidence interval (CI) -0.026 to 0.093) in the first year. PLDD resulted in significantly lower healthcare costs (difference €1771, 95% CI €303 to €3238) and non-significantly lower societal costs (difference €2379, 95% CI -€2860 to €7618). For low values of the willingness to pay for a QALY, the probability of being cost-effective is in favor of PLDD. For higher values of the willingness to pay, between €30,000 and €70,000, conventional microdiscectomy becomes favorable. Conclusions From a healthcare perspective PLDD, followed by surgery when needed, results in significantly lower 1-year costs than conventional surgery. From a societal perspective PLDD appears to be an economically neutral innovation. AD - 1 Leiden University Medical Center, Leiden, Netherlands. 2 Karolinska University Hospital, Solnavägen, Stockholm, Sweden. 3 Erasmus University Medical Center, Rotterdam, Netherlands. AN - 28679342 AU - van den Akker-van Marle, M. E. AU - Brouwer, P. A. AU - Brand, R. AU - Koes, B. AU - van den Hout, W. B. AU - van Buchem, M. A. AU - Peul, W. C. C2 - PMC5624405 DA - Oct DO - 10.1177/1591019917710297 DP - NLM ET - 2017/07/07 IS - 5 KW - Adolescent Adult Aged Cost-Benefit Analysis Decompression, Surgical/economics/*methods *Diskectomy/economics Female Humans Intervertebral Disc Displacement/*complications/*surgery Laser Therapy/economics/*methods Male Middle Aged Pain Measurement Quality of Life Sciatica/*etiology/*prevention & control Surveys and Questionnaires Treatment Outcome Disk herniation laser percutaneous spinal intervention LA - eng N1 - 2385-2011 van den Akker-van Marle, M Elske Brouwer, Patrick A Brand, Ronald Koes, Bart van den Hout, Wilbert B van Buchem, Mark A Peul, Wilco C Comparative Study Journal Article Randomized Controlled Trial Interv Neuroradiol. 2017 Oct;23(5):538-545. doi: 10.1177/1591019917710297. Epub 2017 Jul 5. PY - 2017 SN - 1591-0199 (Print) 1591-0199 SP - 538-545 ST - Percutaneous laser disc decompression versus microdiscectomy for sciatica: Cost utility analysis alongside a randomized controlled trial T2 - Interv Neuroradiol TI - Percutaneous laser disc decompression versus microdiscectomy for sciatica: Cost utility analysis alongside a randomized controlled trial VL - 23 ID - 3785 ER - TY - JOUR AB - OBJECTIVE: To determine whether the faster recovery after early surgery for sciatica compared with prolonged conservative care is attained at reasonable costs. DESIGN: Cost utility analysis alongside a randomised controlled trial. SETTING: Nine Dutch hospitals. PARTICIPANTS: 283 patients with sciatica for 6-12 weeks, caused by lumbar disc herniation. INTERVENTIONS: Six months of prolonged conservative care compared with early surgery. MAIN OUTCOME MEASURES: Quality adjusted life years (QALYs) at one year and societal costs, estimated from patient reported utilities (UK and US EuroQol, SF-6D, and visual analogue scale) and diaries on costs (healthcare, patient's costs, and productivity). RESULTS: Compared with prolonged conservative care, early surgery provided faster recovery, with a gain in QALYs according to the UK EuroQol of 0.044 (95% confidence interval 0.005 to 0.083), the US EuroQol of 0.032 (0.005 to 0.059), the SF-6D of 0.024 (0.003 to 0.046), and the visual analogue scale of 0.032 (-0.003 to 0.066). From the healthcare perspective, early surgery resulted in higher costs (difference euro1819 (pound1449; $2832), 95% confidence interval euro842 to euro2790), with a cost utility ratio per QALY of euro41 000 (euro14,000 to euro430 000). From the societal perspective, savings on productivity costs led to a negligible total difference in cost (euro-12, euro-4029 to euro4006). CONCLUSIONS: Faster recovery from sciatica makes early surgery likely to be cost effective compared with prolonged conservative care. The estimated difference in healthcare costs was acceptable and was compensated for by the difference in absenteeism from work. For a willingness to pay of euro40,000 or more per QALY, early surgery need not be withheld for economic reasons. Trial registration Current Controlled Trials ISRCTN 26872154. AD - Department of Medical Decision Making, Leiden University Medical Center, PO Box 9600, 2300RC Leiden, Netherlands. hout@lumc.nl AN - 18502912 AU - van den Hout, W. B. AU - Peul, W. C. AU - Koes, B. W. AU - Brand, R. AU - Kievit, J. AU - Thomeer, R. T. C2 - PMC2427123 DA - Jun 14 DO - 10.1136/bmj.39583.709074.BE DP - NLM ET - 2008/05/27 IS - 7657 KW - Adolescent Adult Aged Cost-Benefit Analysis Health Care Costs Humans Intervertebral Disc Displacement/complications/economics/*surgery Middle Aged Netherlands Quality-Adjusted Life Years Sciatica/economics/etiology/*surgery LA - eng N1 - 1756-1833 van den Hout, Wilbert B Peul, Wilco C Koes, Bart W Brand, Ronald Kievit, Job Thomeer, Ralph T W M Leiden-The Hague Spine Intervention Prognostic Study Group Comparative Study Journal Article Multicenter Study Randomized Controlled Trial Research Support, Non-U.S. Gov't BMJ. 2008 Jun 14;336(7657):1351-4. doi: 10.1136/bmj.39583.709074.BE. Epub 2008 May 23. PY - 2008 SN - 0959-8138 (Print) 0959-8138 SP - 1351-4 ST - Prolonged conservative care versus early surgery in patients with sciatica from lumbar disc herniation: cost utility analysis alongside a randomised controlled trial T2 - Bmj TI - Prolonged conservative care versus early surgery in patients with sciatica from lumbar disc herniation: cost utility analysis alongside a randomised controlled trial VL - 336 ID - 3702 ER - TY - JOUR AB - Intensive group training using principles of graded activity has been proven to be effective in occupational care for workers with chronic low back pain. Objective of the study was to compare the effects of an intensive group training protocol aimed at returning to normal daily activities and guideline physiotherapy for primary care patients with non-specific chronic low back pain. The study was designed as pragmatic randomised controlled trial with a setup of 105 primary care physiotherapists in 49 practices and 114 patients with non-specific low back pain of more than 12 weeks duration participated in the study. In the intensive group training protocol exercise therapy, back school and operant-conditioning behavioural principles are combined. Patients were treated during 10 individual sessions along 20 group sessions. Usual care consisted of physiotherapy according to the Dutch guidelines for Low Back Pain. Main outcome measures were functional disability (Roland Morris disability questionnaire), pain intensity, perceived recovery and sick leave because of low back pain assessed at baseline and after 6, 13, 26 and 52 weeks. Both an intention-to-treat analysis and a per-protocol analysis were performed. Multilevel analysis did not show significant differences between both treatment groups on any outcome measures during the complete follow-up period, with one exception. After 26 weeks the protocol group showed more reduction in pain intensity than the guideline group, but this difference was absent after 52 weeks. We finally conclude that an intensive group training protocol was not more effective than usual physiotherapy for chronic low back pain. AD - EMGO-Institute, VU University Medical Center, Amsterdam, The Netherlands. AN - 18663487 AU - van der Roer, N. AU - van Tulder, M. AU - Barendse, J. AU - Knol, D. AU - van Mechelen, W. AU - de Vet, H. C2 - PMC2527421 DA - Sep DO - 10.1007/s00586-008-0718-6 DP - NLM ET - 2008/07/30 IS - 9 KW - Activities of Daily Living Adolescent Adult Aged Chronic Disease Cost-Benefit Analysis Female Follow-Up Studies *Guidelines as Topic Health Surveys Humans Low Back Pain/*therapy Male Middle Aged *Occupational Health Outcome Assessment, Health Care *Physical Therapy Modalities/economics Primary Health Care *Psychotherapy, Group/economics Treatment Outcome Young Adult LA - eng N1 - 1432-0932 van der Roer, Nicole van Tulder, Maurits Barendse, Johanna Knol, Dirk van Mechelen, Willem de Vet, Henrica Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't Eur Spine J. 2008 Sep;17(9):1193-200. doi: 10.1007/s00586-008-0718-6. Epub 2008 Jul 29. PY - 2008 SN - 0940-6719 (Print) 0940-6719 SP - 1193-200 ST - Intensive group training protocol versus guideline physiotherapy for patients with chronic low back pain: a randomised controlled trial T2 - Eur Spine J TI - Intensive group training protocol versus guideline physiotherapy for patients with chronic low back pain: a randomised controlled trial VL - 17 ID - 3584 ER - TY - JOUR AB - OBJECTIVES: Children with functional abdominal pain (FAP) frequently report comorbid complaints such as anxiety and activity limitations. Their parents often experience heightened levels of anxiety, depression, and somatization. The aim of the present study was to investigate whether these comorbid complaints in children and their parents are specific for FAP or can also be found in a community sample. PATIENTS AND METHODS: Six hundred sixty-five schoolchildren (ages 7-18 years) filled out questionnaires concerning AP, activity limitations, somatic complaints, quality of life, and symptoms of anxiety and depression. A total of 391 of their parents filled out questionnaires concerning parental anxiety, depression, and somatization. Pearson correlations and multiple regression analyses were performed. RESULTS: A total of 56.5% of the children reported AP at least once in a 2-week period. Univariate relations with AP were found for activity limitations (r = 0.392), somatic complaints (r = 0.408), 3 of 5 domains of quality of life (r ranging from -0.120 to -0.209), and symptoms of anxiety and depression (r, respectively, 0.329 and 0.361). Multivariate analyses showed only significant relations for female sex (β = 0.230), younger age (β = -0.077), activity limitations (β = 0.247), somatic complaints (β = 0.170), and depressive symptoms (β = 0.093). CONCLUSIONS: Activity limitations, somatic complaints, and depressive symptoms are related to AP in the general population, whereas a reduced quality of life, anxiety, and parental internalizing problems seem specific comorbid complaints for FAP. Future research on parental internalizing problems, quality of life, and anxiety as risk factors for FAP is warranted. AU - van der Veek, Shelley M. C. AU - Derkx, H. H. F. AU - de Haan, Else AU - Benninga, Marc A. AU - Boer, Frits DA - 2010/10// DO - 10.1097/MPG.0b013e3181d51a59 DP - PubMed IS - 4 J2 - J Pediatr Gastroenterol Nutr KW - Abdominal Pain Adolescent Age Distribution Anxiety Disorders Child Comorbidity Cross-Sectional Studies Depressive Disorder Female Health Status Humans Male Mental Disorders Motor Activity Netherlands Parents Quality of Life Sex Distribution Somatoform Disorders Surveys and Questionnaires LA - eng PY - 2010 SN - 1536-4801 SP - 481-487 ST - Abdominal pain in Dutch schoolchildren T2 - Journal of Pediatric Gastroenterology and Nutrition TI - Abdominal pain in Dutch schoolchildren: relations with physical and psychological comorbid complaints in children and their parents UR - http://www.ncbi.nlm.nih.gov/pubmed/20562723 VL - 51 ID - 105 ER - TY - JOUR AB - Objective: Physical symptoms, such as musculoskeletal pain, dizziness, or headache, are common. People with more symptoms are reported to use more healthcare and have higher sickness absenteeism. We studied the impact of the number of symptoms on perceived health in a community sample. Methods: Between June 2005 and March 2006, a random sample of 4741 adults was selected from the records of five general practices in The Netherlands. They were sent a questionnaire regarding the frequency and impact of physical symptoms, and other factors that may influence health (potential confounders or modifiers), including lifestyle factors, childhood illness experiences, and psychological factors. We studied the association between increasing number of physical symptoms and perceived health using the SF-36 as the outcome measure. Results: Response rate was 53.5% (n=2447). Fatigue was the most commonly reported symptom with a prevalence of 57%, followed by headache (40%) and back pain (39%). More than half of responders reported three symptoms or more. Responders with multiple symptoms were more often female, had lower educational level, less often paid work, higher body mass index, more negative childhood health experiences, and higher scores for anxiety and depression. Multiple symptoms were strongly associated with perceived health, especially among responders with negative illness perceptions, more anxiety, or those reporting family members with a chronic illness during childhood. Conclusion: Physical symptoms are common and often seem to be mild. However, increasing number of symptoms is strongly associated with poorer physical, emotional, and social functioning. Different somatization processes may explain our findings. (C) 2008 Elsevier Inc. All rights reserved. AN - WOS:000253789600004 AU - van der Windt, Dawm AU - Dunn, K. M. AU - Spies-Dorgelo, M. N. AU - Mallen, C. D. AU - Blankenstein, A. H. AU - Stalman, W. A. B. DA - Mar DO - 10.1016/j.jpsychores.2007.10.003 IS - 3 N1 - van der Windt, Danielle A. W. M. Dunn, Kate M. Spies-Dorgelo, Marinda N. Mallen, Christian D. Blankenstein, Antoinette H. Stalman, Wim A. B. Dunn, kate/a-8712-2008 Mallen, Christian/0000-0002-2677-1028 1879-1360 PY - 2008 SN - 0022-3999 SP - 265-274 ST - Impact of physical symptoms on perceived health in the community T2 - Journal of Psychosomatic Research TI - Impact of physical symptoms on perceived health in the community UR - ://WOS:000253789600004 VL - 64 ID - 2661 ER - TY - JOUR AB - BACKGROUND: Despite significant progress in the epidemiology of chronic pain in adults, major gaps remain in our understanding of the epidemiology of chronic pain in children. In particular, the incidence, prevalence and sensory characteristics of many types of pain in Canadian children are unknown. OBJECTIVES: A study to obtain the lifetime and point prevalence of common acute pains, recurrent pain syndromes and chronic pains was conducted in a cohort of 495 school children, nine to 13 years of age, in eastern Ontario. METHODS: Children reported their pain experiences and described the intensity, affect and duration of the pains experienced over the previous month by completing the Pain Experience Interview -- Short Form. RESULTS: The majority of children (96%) experienced some acute pain over the previous month, with headache (78%) being most frequently reported. Lifetime prevalence for certain acute pains differed significantly by sex (P<0.05). Fifty-seven per cent of children reported experiencing at least one recurrent pain, while 6% were identified as having had or currently having chronic pain. DISCUSSION: The prevalence of acute pain in this Canadian cohort is consistent with international estimates of acute pain experiences (ie, headache) and recurrent pain problems (ie, recurring headache, abdominal pain and growing pains). However, 6% of children reported chronic pain. The self-completed Pain Experience Interview--Short Form provides a feasible administration technique for obtaining population estimates of childhood pain, and for conducting longitudinal studies to identify risk and prognostic factors for chronic pain. AU - van Dijk, Adam AU - McGrath, Patricia A. AU - Pickett, William AU - VanDenKerkhof, Elizabeth G. DA - 2006 DO - 10.1155/2006/835327 DP - PubMed IS - 4 J2 - Pain Res Manag KW - Adolescent Child Cross-Sectional Studies Female Humans Interviews as Topic Male Ontario Pain Pain Measurement Prevalence Schools Sex Factors Students Surveys and Questionnaires LA - eng PY - 2006 SN - 1203-6765 SP - 234-240 ST - Pain prevalence in nine- to 13-year-old schoolchildren T2 - Pain Research & Management TI - Pain prevalence in nine- to 13-year-old schoolchildren UR - http://www.ncbi.nlm.nih.gov/pubmed/17149456 VL - 11 ID - 109 ER - TY - JOUR AB - Objective: To release a newly protocolized behavioral intervention program for children with chronic constipation aged 4-18 years with guidance from literature about underlying theories from which the treatment techniques follow. Methods: Articles until July 2006 were identified through electronic searches in Medline, PsychInfo and Picarta. There was no limit placed on the time periods searched. Following keywords were used: constipation, encopresis, fecal incontinence, psychotherapy, emotions, randomized controlled trials, parent-child relations, parents, family, psychology, behavioral, behavioral problems, psychopathology, toilet, social, psychosocial, pain, retentive posturing. stool withholding, stool toileting refusal, shame, stress, anxiety. A filter was used to select literature referring to children 0-18 years old. Key constructs and content of sessions for a protocolized behavioral intervention program are derived from literature. Results: Seventy-one articles on chronic childhood constipation are critically reviewed and categorized into sections on epidemiology, symptomatology, etiology and consequences, treatment and effectivity, and follow-up on chronic childhood constipation. This is followed by an extensive description of our protocolized behavioral intervention program. Conclusion: This is the first article on childhood constipation presenting a full and transparent description of a behavioral intervention program embedded in literature. In addition, a theoretical framework is provided that can serve as a trial paradigm to evaluate intervention effectiveness. Practice implications: This article can serve as an extensive guideline in routine practice to treat chronically constipated children. By releasing our protocolized behavioral intervention program and by offering a theoretical framework we expect to provide a good opportunity to evaluate clinical effectivity by both randomized controlled trials and qualitative research methods. Findings will contribute to the implementation of an effective treatment for chronic constipation in childhood. (C) 2007 Elsevier Ireland Ltd. All rights reserved. AN - WOS:000248014200011 AU - van Dijk, M. AU - Benninga, M. A. AU - Grootenhuis, M. A. AU - Onland-van Niettwenhuizen, A. M. AU - Last, B. F. DA - Jul DO - 10.1016/j.pec.2007.02.002 IS - 1-2 N1 - van Dijk, Marieke Benninga, Marc A. Grootenhuis, Martha A. Onland-van Niettwenhuizen, Anne-Martine Last, Bob F. PY - 2007 SN - 0738-3991 SP - 63-77 ST - Chronic childhood constipation: A review of the literature and the introduction of a protocolized behavioral intervention program T2 - Patient Education and Counseling TI - Chronic childhood constipation: A review of the literature and the introduction of a protocolized behavioral intervention program UR - ://WOS:000248014200011 VL - 67 ID - 2685 ER - TY - JOUR AB - Potentially painful procedures are only one of many distressing aspects related to hospital stay. Any child hospitalized for extended periods of time at an early age is deprived of normal daily care by parents or caretakers. The detrimental effects of hospitalization, however, may be diminished by optimal care, including the best possible pain treatment and, preferably, pain prevention. This optimal care may be achieved by a combination of pharmacologic treatment such as analgesics and/or sedatives and nonpharmacologic treatment such as massage, swaddling, and optimal environmental conditions. Especially in preverbal infants with a limited ability to express themselves, it may be helpful to use standardized pain assessment approaches to guide pain treatment. Two groups of preverbal infants who require special attention are critically ill infants (of which the very prematurely born neonates may be considered a subgroup) and neurologically impaired and/or cognitively impaired infants. When an infant is critically ill, too tired to respond vigorously to treatment, or mechanically ventilated and, occasionally, chemically paralyzed, other cues are needed to determine their level of pain and distress. Especially during invasive procedures, premature neonates show considerable discomfort, without the consolation, for example, of being held by a parent. It remains difficult to ascertain, however, whether they are in pain or distress. In another group of children-the cognitively or neurologically impaired infants-one can feel powerless because it is so difficult to discriminate "normal" behavior from pain-specific behavior in these infants. These examples illustrate the problem of pain assessment in children with special health care needs or developmental disabilities. This issue was recently underlined by a publication of the American Academic of Pediatrics in collaboration with the American Pain Society [1]. Based on the authors' review of the literature on pediatric postoperative pain assessment with special attention to groups of vulnerable infants, this article (1) reports on type of surgery and its relationship to postoperative pain intensity; (2) reviews the characteristics of existing postoperative pain instruments for neonates, infants, and toddlers; (3) discusses timing, duration, and who should assess postoperative pain; (4) reviews the specific literature on pain assessment in critically ill infants, including the extremely low birth weight (ELBW) and the cognitively and/or neurologically impaired infant, and (5) discusses the role of parents in postoperative pain assessment. Finally, the authors draw some conclusions and make recommendations concerning postoperative pain assessment for future research. AN - WOS:000178353300009 AU - van Dijk, M. AU - Peters, J. W. B. AU - Bouwmeester, N. J. AU - Tibboel, D. C7 - Pii s0095-5108(02)00015-5 DA - Sep DO - 10.1016/s0095-5108(02)00015-5 IS - 3 N1 - van Dijk, M Peters, JWB Bouwmeester, NJ Tibboel, D van Dijk, Monique/B-6327-2009 van Dijk, Monique/0000-0002-9856-0318 1557-9840 PY - 2002 SN - 0095-5108 SP - 469-+ ST - Are postoperative pain instruments useful for specific groups of vulnerable infants? T2 - Clinics in Perinatology TI - Are postoperative pain instruments useful for specific groups of vulnerable infants? UR - ://WOS:000178353300009 VL - 29 ID - 2823 ER - TY - JOUR AB - STUDY DESIGN: A cross-sectional study of 745 young adolescents in the area of two Regional Health Centers in the Netherlands. OBJECTIVES: To assess the occurrence of neck and/or shoulder and back complaints in young adolescents and examine relationships with type and weight of schoolbags and other physical and psychologic risk factors. SUMMARY OF BACKGROUND DATA: The occurrence of back pain in children and adolescents varies from 8% to 74% in the literature. Age, gender, and certain psychological factors appear to be important risk factors. An association with heavy schoolbags has been presumed but without clear scientific evidence. METHODS: A questionnaire was used, asking about complaints of back, neck, and/or shoulders and about potential risk factors including psychosomatic factors. Length and weight of the children were determined. Schoolbags were weighed, and the relative weight of the schoolbag was calculated. RESULTS: Neck and/or shoulder complaints and also back complaints were reported by about 45% of young adolescents. Severe complaints of neck and/or shoulder were reported by 6%, and severe back complaints by 7% of the schoolchildren. The (relative) weight of schoolbags was not related to complaints of neck and/or shoulder and back. Psychosomatic factors showed the strongest association with the occurrence of neck and/or shoulder and back complaints. CONCLUSION: Psychosomatic factors appear to be more strongly related to the occurrence of neck and/or shoulder and back complaints than the type and weight of the schoolbag and other physical factors. The role of psychosomatic factors should be further explored in future longitudinal research. AU - van Gent, Charlotte AU - Dols, Joselien J. C. M. AU - de Rover, Carolien M. AU - Hira Sing, Remy A. AU - de Vet, Henrica C. W. DA - 2003/05/01/ DO - 10.1097/01.BRS.0000058721.69053.EC DP - PubMed IS - 9 J2 - Spine (Phila Pa 1976) KW - Adolescent Back Pain Body Weight Causality Child Comorbidity Cross-Sectional Studies Female Health Surveys Humans Male Neck Pain Netherlands Risk Factors Schools Shoulder Pain Students Surveys and Questionnaires Weight-Bearing LA - eng PY - 2003 SN - 1528-1159 SP - 916-921 ST - The weight of schoolbags and the occurrence of neck, shoulder, and back pain in young adolescents T2 - Spine TI - The weight of schoolbags and the occurrence of neck, shoulder, and back pain in young adolescents UR - http://www.ncbi.nlm.nih.gov/pubmed/12942008 VL - 28 ID - 125 ER - TY - JOUR AB - Background Having Juvenile idiopathic Arthritis (JIA) has widespread implications for a person's life. Patients have to deal with recurring arthritis, characterized by pain often accompanied by a loss of energy. Since JIA often persists into adulthood, patients with JIA are likely to encounter difficulties in their working life. We expect that the experiences in school life may be comparable to the barriers and opportunities which patients affected by JIA encounter in adult working life. Therefore, the aim of this study was to elicit the experiences during school life and the perspectives and expectations regarding future work participation of adolescents with JIA. Methods This study used individual, semi-structured interviews and followed a predefined interview guide. Participants between 14 and 18 years of age (n = 22) were purposively selected to achieve a broad range of participant characteristics. Open coding was performed, followed by axial coding and selective coding. Results Great differences were seen in the support and understanding that adolescents received in dealing with JIA at school, leisure activities and work. Varying approaches were mentioned on how to pursue a desired vocation. Perspectives regarding disclosure varied. Participants wished to be approached like any other healthy adolescent. Expectations regarding work participation were positively expressed. Conclusion This study showed that participants often disregarded having JIA when making plans for their future career. Facilitating an open discussion about the possible limitations accompanying JIA with educators and employers might prevent overburden and increase the chance of starting a career which would accommodate the patient with JIA in the near and distant future. AN - WOS:000528697200003 AU - van Gulik, E. C. AU - Verkuil, F. AU - Barendregt, A. M. AU - Schonenberg-Meinema, D. AU - Rashid, A. N. S. AU - Kuijpers, T. W. AU - van den Berg, J. M. AU - Hoving, J. L. C7 - 33 DA - Apr DO - 10.1186/s12969-020-00429-6 IS - 1 N1 - van Gulik, E. Charlotte Verkuil, Floris Barendregt, Anouk M. Schonenberg-Meinema, Dieneke Rashid, Amara Nassar-Sheikh Kuijpers, Taco W. van den Berg, J. Merlijn Hoving, Jan L. Hoving, Jan L/O-2235-2013 Hoving, Jan L/0000-0002-0461-4013; van den Berg, J.Merlijn/0000-0001-9431-5457 1546-0096 PY - 2020 ST - Experiences, perspectives and expectations of adolescents with juvenile idiopathic arthritis regarding future work participation; a qualitative study T2 - Pediatric Rheumatology TI - Experiences, perspectives and expectations of adolescents with juvenile idiopathic arthritis regarding future work participation; a qualitative study UR - ://WOS:000528697200003 VL - 18 ID - 1827 ER - TY - JOUR AB - Objectives: Pain disorders tend to run in families, and children of individuals with chronic pain have been found to report lower functioning. Drawing upon a social learning perspective, the current study examined how diverse maternal pain coping responses (ie, pain catastrophizing and distraction) may, via corresponding child pain coping responses, act as a vulnerability or protective factor for child functioning in the context of parental chronic pain (CP). Methods: A cross-sectional study was conducted in mothers with CP and their pain-free child (N=100) and mothers without CP and their pain-free child (N=74). Moderated mediation analyses were performed to test whether associations between maternal coping responses and child functioning (ie, somatic symptoms, physical functioning, and psychosocial health) were mediated by corresponding child coping responses and whether these associations were moderated by the presence or absence of maternal CP. Results: Maternal pain catastrophizing was indirectly related to more somatic symptoms, lower physical functioning, and lower psychosocial health in their child via child pain catastrophizing. Relationships were moderated by the presence or absence of maternal CP, such that mediated relationships were only found in mothers without CP and their child. No (in)direct relationships between maternal distraction, child distraction, and child functioning were observed. Discussion: The current findings demonstrated that child functioning was associated with maternal and child pain catastrophizing, but only in children of mothers without CP. No evidence was found in support of maternal pain coping responses as vulnerability or protective factors in the context of parental CP. AN - WOS:000525468200002 AU - Van Lierde, E. AU - Goubert, L. AU - Lammens, T. AU - Ben Brahim, L. AU - Van den Bussche, E. AU - Vervoort, T. DA - Apr DO - 10.1097/ajp.0000000000000801 IS - 4 N1 - Van Lierde, Elke Goubert, Liesbet Lammens, Tim Ben Brahim, Lamia Van den Bussche, Eva Vervoort, Tine ; Goubert, Liesbet/J-9607-2012; Van den Bussche, Eva/E-7977-2010 Vervoort, Tine/0000-0002-9601-8525; Goubert, Liesbet/0000-0002-7657-5148; Van den Bussche, Eva/0000-0003-1894-9380 1536-5409 PY - 2020 SN - 0749-8047 SP - 238-248 ST - The Interplay of Parent and Child Coping Responses in Understanding Child Functioning in the Context of Living With a Parent With or Without Chronic Pain T2 - Clinical Journal of Pain TI - The Interplay of Parent and Child Coping Responses in Understanding Child Functioning in the Context of Living With a Parent With or Without Chronic Pain UR - ://WOS:000525468200002 VL - 36 ID - 1830 ER - TY - JOUR AB - BACKGROUND: Children of individuals with chronic pain have an increased vulnerability to experience pain problems, possibly through observation of pain in their parents. As pain-related fear (PRF) is a critical factor in the development and maintenance of chronic pain, the current experimental study examined the acquisition of PRF through observational learning and subsequent extinction after first-hand experience of the feared stimulus. METHODS: Healthy children (8-16 years) observed either their mother or a stranger performing two cold pressor tasks (CPT) filled with coloured water. In a differential conditioning procedure, one colour (CS+) was combined with genuine painful facial expressions and the other colour (CS-) with neutral facial expressions. Following this observation phase, children performed both CPTs (10°C) themselves. RESULTS: Children expected the CS+ to be more painful than the CS- and they reported being more afraid and hesitant to immerse in the CS+ compared to the CS-. Moreover, this fear was reflected in children's level of arousal in anticipation of CPT performance. This learned association extinguished after performing both CPTs. Effects were not moderated by whether the child observed their mother or a stranger, by the child's pain catastrophizing, trait PRF or trait anxiety. Remarkably, learning effects increased when the child perceived a larger difference between the model's painful and neutral facial expressions. CONCLUSIONS: This study provides evidence for observational learning of PRF and subsequent extinction in schoolchildren. This acquisition of PRF by observing parental pain may contribute to vulnerabilities in children of parents with chronic pain. SIGNIFICANCE: Children may acquire pain-related fear by observing pain in others and this learned fear can diminish after first-hand experience. Remarkably, observational learning did not depend on the children's relationship with the model, but it did depend on the intensity of pain that is perceived. A better understanding of the impact of observing (parental) pain may help clarify the intergenerational transmission of risk for pain and inform the development of preventive programs. AD - Department of Experimental-Clinical and Health Psychology, Ghent University, Ghent, Belgium. Department of Experimental and Applied Psychology, Vrije Universiteit Brussel, Brussels, Belgium. Department of Psychology, University of Essex, Colchester, UK. Brain & Cognition, KU Leuven, Leuven, Belgium. AN - 31886912 AU - Van Lierde, E. AU - Goubert, L. AU - Vervoort, T. AU - Hughes, G. AU - Van den Bussche, E. DA - Apr DO - 10.1002/ejp.1529 DP - NLM ET - 2019/12/31 IS - 4 KW - *Catastrophization Child Extinction, Psychological Facial Expression *Fear Humans Learning *Pain/psychology Pain Measurement LA - eng N1 - 1532-2149 Van Lierde, Elke Orcid: 0000-0001-7303-6854 Goubert, Liesbet Vervoort, Tine Hughes, Gethin Van den Bussche, Eva 11ZY917N/Fund for Scientific Research - Flanders/International Journal Article Research Support, Non-U.S. Gov't England Eur J Pain. 2020 Apr;24(4):791-806. doi: 10.1002/ejp.1529. Epub 2020 Jan 22. PY - 2020 SN - 1090-3801 SP - 791-806 ST - Learning to fear pain after observing another's pain: An experimental study in schoolchildren T2 - Eur J Pain TI - Learning to fear pain after observing another's pain: An experimental study in schoolchildren VL - 24 ID - 3993 ER - TY - JOUR AB - Chronic recurrent abdominal pain is a common complaint evaluated by pediatricians, and a cause of concern for children and parents. Population and school based studies have reported that approximately 8% of children experience chronic abdominal pain. About half of these children will contact a physician about their pain. These children report reduced quality of life and interferences with school and play due to their pain. The large majority of children will not have a readily identified cause for their symptoms, and chronic abdominal pain is frequently classified as a functional gastrointestinal disorder (FGID). The below case study illustrates the presentation, evaluation, and clinical management of a child with chronic abdominal pain. AD - Department of Gastroenterology, University of North Carolina School of Medicine, UNC Center for Functional GI and Motility Disorders, Chapel Hill, NC, USA. AN - 20440238 AU - Van Tilburg, M. A. AU - Chitkara, D. K. DA - Apr DP - NLM ET - 2010/05/05 IS - 2 KW - Abdominal Pain/*etiology Adolescent Female Humans Irritable Bowel Syndrome/*complications/diagnosis/therapy LA - eng N1 - Van Tilburg, M A L Chitkara, D K Case Reports Journal Article Italy Minerva Pediatr. 2010 Apr;62(2):179-87. PY - 2010 SN - 0026-4946 (Print) 0026-4946 SP - 179-87 ST - The clinical approach to chronic abdominal pain and irritable bowel syndrome in children T2 - Minerva Pediatr TI - The clinical approach to chronic abdominal pain and irritable bowel syndrome in children VL - 62 ID - 4006 ER - TY - JOUR AB - OBJECTIVE: This study was designed to develop and to test a home-based, guided imagery treatment protocol, using audio and video recordings, that is easy for health care professionals and patients to use, is inexpensive, and is applicable to a wide range of health care settings. METHODS: Thirty-four children, 6 to 15 years of age, with a physician diagnosis of functional abdominal pain were assigned randomly to receive 2 months of standard medical care with or without home-based, guided imagery treatment. Children who received only standard medical care initially received guided imagery treatment after 2 months. Children were monitored for 6 months after completion of guided imagery treatment. RESULTS: All treatment materials were reported to be self-explanatory, enjoyable, and easy to understand and to use. The compliance rate was 98.5%. In an intention-to-treat analysis, 63.1% of children in the guided imagery treatment group were treatment responders, compared with 26.7% in the standard medical care-only group (P = .03; number needed to treat: 3). Per-protocol analysis showed similar results (73.3% vs 28.6% responders). When the children in the standard medical care group also received guided imagery treatment, 61.5% became treatment responders. Treatment effects were maintained for 6 months (62.5% responders). CONCLUSION: Guided imagery treatment plus medical care was superior to standard medical care only for the treatment of abdominal pain, and treatment effects were sustained over a long period. AD - Center for Functional Gastrointestinal and Motility Disorders, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA. tilburg@med.unc.edu AN - 19822590 AU - van Tilburg, M. A. AU - Chitkara, D. K. AU - Palsson, O. S. AU - Turner, M. AU - Blois-Martin, N. AU - Ulshen, M. AU - Whitehead, W. E. DA - Nov DO - 10.1542/peds.2009-0028 DP - NLM ET - 2009/10/14 IS - 5 KW - Abdominal Pain/psychology/*therapy Absenteeism Adolescent Child Chronic Disease Female Humans *Imagery, Psychotherapy Male Pain Measurement Quality of Life *Tape Recording LA - eng N1 - 1098-4275 van Tilburg, Miranda A L Chitkara, Denesh K Palsson, Olafur S Turner, Marsha Blois-Martin, Nanette Ulshen, Martin Whitehead, William E R24 DK067674/DK/NIDDK NIH HHS/United States RR00046/RR/NCRR NIH HHS/United States Journal Article Randomized Controlled Trial Research Support, N.I.H., Extramural United States Pediatrics. 2009 Nov;124(5):e890-7. doi: 10.1542/peds.2009-0028. Epub 2009 Oct 12. PY - 2009 SN - 0031-4005 SP - e890-7 ST - Audio-recorded guided imagery treatment reduces functional abdominal pain in children: a pilot study T2 - Pediatrics TI - Audio-recorded guided imagery treatment reduces functional abdominal pain in children: a pilot study VL - 124 ID - 3424 ER - TY - JOUR AB - OBJECTIVE: To evaluate the effect of fremanezumab on the functional status on headache-free days in phase 2 episodic migraine (EM) and chronic migraine (CM) studies. METHODS: Functional status data were collected prospectively via the electronic headache diary on all headache-free days by patients answering questions regarding work/school/household chore performance, speed of work completion, concentration, and feeling of fatigue. Individuals with EM receiving monthly doses of fremanezumab 225 mg (n = 96) or 675 mg (n = 97) or placebo (n = 104) were compared. Individuals with CM receiving fremanezumab 675 mg followed by monthly 225 mg (n = 88) and 900 mg (n = 86) were also independently compared to those receiving placebo (n = 89). RESULTS: In patients with EM, compared to patients receiving placebo, those receiving fremanezumab experienced an increased number of headache-free days with normal function in work/school/household chore performance and concentration/mental fatigue measures compared to their baseline over the entire treatment period (all p < 0.005). An increased number of headache-free days with normal functional performance for some measures was also found in the CM group in those treated with fremanezumab. CONCLUSION: There was an increased number of headache-free days with normal functional performance on all measures for the patients with EM and some measures for patients with CM in the fremanezumab-treated groups. Further research is required to confirm these findings in a prospective study and to clarify the underlying mechanism(s). CLINICALTRIALSGOV IDENTIFIER: NCT02025556 and NCT02021773. CLASSIFICATION OF EVIDENCE: This study provides Class II evidence that for patients with migraine, fremanezumab increases normal functional performance on headache-free days. AD - From the Mayo Clinic (J.V., D.W.D.), Phoenix, AZ; Montefiore Headache Center (R.B.L.), Albert Einstein College of Medicine, New York, NY; Teva Pharmaceuticals Ltd (Y.M., P.S.L.), Netanya, Israel; and Teva Pharmaceuticals Ltd (M.E.B.), Frazer, PA. Dr. Bigal is now at Purdue Pharma, Stamford, CT. VanderPluym.Juliana@mayo.edu. From the Mayo Clinic (J.V., D.W.D.), Phoenix, AZ; Montefiore Headache Center (R.B.L.), Albert Einstein College of Medicine, New York, NY; Teva Pharmaceuticals Ltd (Y.M., P.S.L.), Netanya, Israel; and Teva Pharmaceuticals Ltd (M.E.B.), Frazer, PA. Dr. Bigal is now at Purdue Pharma, Stamford, CT. AN - 30120138 AU - VanderPluym, J. AU - Dodick, D. W. AU - Lipton, R. B. AU - Ma, Y. AU - Loupe, P. S. AU - Bigal, M. E. C2 - PMC6161555 DA - Sep 18 DO - 10.1212/01.wnl.0000544321.19316.40 DP - NLM ET - 2018/08/19 IS - 12 KW - *Academic Performance Adolescent Adult Aged Antibodies, Monoclonal/adverse effects/*therapeutic use Clinical Trials, Phase II as Topic/*statistics & numerical data Drug Administration Schedule Fatigue/complications/drug therapy Female Humans Male Medical Records Middle Aged Migraine Disorders/complications/drug therapy/*prevention & control *Physical Functional Performance Prospective Studies *Work Performance Young Adult LA - eng N1 - 1526-632x VanderPluym, Juliana Dodick, David W Lipton, Richard B Ma, Yuju Loupe, Pippa S Bigal, Marcelo E Journal Article Research Support, Non-U.S. Gov't Neurology. 2018 Sep 18;91(12):e1152-e1165. doi: 10.1212/01.wnl.0000544321.19316.40. Epub 2018 Aug 17. PY - 2018 SN - 0028-3878 (Print) 0028-3878 SP - e1152-e1165 ST - Fremanezumab for preventive treatment of migraine: Functional status on headache-free days T2 - Neurology TI - Fremanezumab for preventive treatment of migraine: Functional status on headache-free days VL - 91 ID - 3049 ER - TY - JOUR AB - Background.-To use a case-control design to evaluate the emotional and behavioral functioning of children with migraine. Method.-Research has indicated that children with migraine are at increased risk for emotional and behavioral problems such as depression and anxiety; however, methodological limitations in sample definitions, measurement strategies, and comparison groups remain problematic. Results.-Forty-seven participants diagnosed with migraine at a pediatric headache center participated in a home-based study of child functioning using standardized measures. Mothers and fathers of these children participated, as did control families recruited from among classmates. Results.-Indications of increased emotional and behavioral difficulties for children with migraine were found, primarily from the perspective of mothers. Exploratory analyses found several associations between mother and child perceptions of difficulties and persistence of headache symptoms following initiation of multidisciplinary headache treatment. Conclusions.-Continued concern regarding emotional well-being of children with migraine is warranted, but more work is needed to understand the differing perspectives of family members. Particular attention to emotional well-being is needed for children whose headache symptoms persist despite multidisciplinary treatment. AN - WOS:000257483200002 AU - Vannatta, K. AU - Getzoff, E. A. AU - Powers, S. W. AU - Noll, R. B. AU - Gerhardt, C. A. AU - Hershey, A. D. DA - Jul-Aug DO - 10.1111/j.1526-4610.2007.01051.x IS - 7 N1 - Vannatta, Kathryn Getzoff, Elizabeth A. Powers, Scott W. Noll, Robert B. Gerhardt, Cynthia A. Hershey, Andrew D. Vannatta, Kathryn/E-4237-2011; Gerhardt, Cynthia/E-3109-2011; Hershey, Andrew D./K-1245-2019 Hershey, Andrew D./0000-0002-1598-7536; Powers, Scott/0000-0002-5348-9650 PY - 2008 SN - 0017-8748 SP - 994-1004 ST - Multiple perspectives on the psychological functioning of children with and without migraine T2 - Headache TI - Multiple perspectives on the psychological functioning of children with and without migraine UR - ://WOS:000257483200002 VL - 48 ID - 2642 ER - TY - JOUR AB - Objective. The Pediatric Quality of Life Inventory (PedsQL) is a modular instrument designed to measure health-related quality of life (HRQOL) in children and adolescents ages 2-18 years. The 23-item PedsQL 4.0 Generic Core Scales are multidimensional child self-report and parent proxy-report scales developed as the generic core measure to be integrated with the PedsQL disease-specific modules. The 22-item PedsQL 3.0 Rheumatology Module was designed to measure pediatric rheumatology-specific HRQOL. This study was undertaken to demonstrate the reliability, validity, and responsiveness of the PedsQL 4.0 Generic Core Scales and the PedsQL 3.0 Rheumatology Module in pediatric rheumatology. Methods. The 4 PedsQL 4.0 Generic Core Scales (physical, emotional, social, and school functioning) and the 5 PedsQL 3.0 Rheumatology Module scales (pain and hurt, daily activities, treatment, worry, an communication) were administered to 231 children and 244 parents (271 subjects accrued overall) recruited from a pediatric rheumatology clinic. Results. Internal consistency reliability for the PedsQL Generic Core total scale score (alpha = 0.91 for child self report, alpha = 0.93 for parent proxy report), physical health summary score (alpha = 0.87 for child self report, alpha = 0.89 for parent proxy, report), and psychosocial health summary score (alpha = 0.86 for child self report, alpha = 0.90 for parent proxy report) were acceptable for group comparisons. The Rheumatology Module scales also demonstrated acceptable reliability for group comparisons (alpha = 0.75-0.86 for child self report, alpha = 0.82-0.91 for parent proxy, report). Validity was demonstrated using the known-groups method. The PedsQL distinguished between healthy children and children with rheumatic diseases as a group. The responsiveness of the PedsQL was demonstrated through patient change over time as a result of clinical intervention. Conclusion. The results demonstrate the reliability, validity, and responsiveness of the PedsQL 4.0 Generic Core Scales and the PedsQL 3.0 Rheumatology Module in pediatric rheumatology. AN - WOS:000174409200018 AU - Varni, J. W. AU - Seid, M. AU - Knight, T. S. AU - Burwinkle, T. AU - Brown, J. AU - Szer, I. S. DA - Mar DO - 10.1002/art.10095 IS - 3 N1 - Varni, JW Seid, M Knight, TS Burwinkle, T Brown, J Szer, IS PY - 2002 SN - 0004-3591 SP - 714-725 ST - The PedsQL (TM) in pediatric rheumatology - Reliability, validity, and responsiveness of the Pediatric Quality of Life Inventory (TM) generic core scales and rheumatology module T2 - Arthritis and Rheumatism TI - The PedsQL (TM) in pediatric rheumatology - Reliability, validity, and responsiveness of the Pediatric Quality of Life Inventory (TM) generic core scales and rheumatology module UR - ://WOS:000174409200018 VL - 46 ID - 2835 ER - TY - JOUR AB - The PedsQL(TM) 4.0 (Pediatric Quality of Life Inventory(TM)) Generic Core Scales are child self-report and parent proxy-report scales developed to measure health-related quality of life (HRQOL) in children and adolescents ages 2-18. The PedsQL(TM) 4.0 Generic Core Scales consist of 23 items applicable for healthy school and community populations and pediatric populations with acute and chronic health conditions. The 4 PedsQL(TM) 4.0 Generic Core Scales (Physical, Emotional, Social., School) were administered to 209 children and 269 parents (289 subjects accrued overall) recruited from pediatric cardiology, orthopedics, and rheumatology clinics. Sensitivity, responsiveness, and the impact on clinical decision-making were determined. The PedsQL(TM) was differentially sensitive to increasing degrees of cardiac disease severity in the cardiology clinic setting and responsive to clinical change over time in the pediatric orthopedics clinic setting. In the pediatric rheumatology clinic setting, the PedsQL(TM) demonstrated an impact on clinical decision-making, resulting in subsequent increases in HRQOL. AN - WOS:000175034200005 AU - Varni, J. W. AU - Seid, M. AU - Knight, T. S. AU - Uzark, K. AU - Szer, I. S. DA - Apr DO - 10.1023/a:1014836921812 IS - 2 N1 - Varni, JW Seid, M Knight, TS Uzark, K Szer, IS PY - 2002 SN - 0160-7715 SP - 175-193 ST - The PedsQL (TM) 4.0 Generic Core Scales: Sensitivity, responsiveness, and impact on clinical decision-making T2 - Journal of Behavioral Medicine TI - The PedsQL (TM) 4.0 Generic Core Scales: Sensitivity, responsiveness, and impact on clinical decision-making UR - ://WOS:000175034200005 VL - 25 ID - 2833 ER - TY - JOUR AB - BACKGROUND. The PedsQL (Pediatric Qualify of Life Inventory) (Children's Hospital and Health Center, San Diego, California) is a modular instrument for measuring health-related quality of life (HRQOL) in children and adolescents ages 2 to I8. The PedsQL 4.0 Generic Core Scales are multidimensional child self-report and parent proxy-report scales developed as the generic care measure to be integrated with fine PedsQL Disease-Specific Modules. The PedsQL 4.0 Generic Core Scales consist of 23 items applicable for healthy school and community populations, as well as pediatric populations with acute and chronic health conditions. METHODS. The 4 PedsQL 4.0 Generic Core Scales (Physical, Emotional, Social, School) were administered to 963 children and 1,629 parents (1,677 subjects accrued overall) recruited from pediatric health care settings. Item-level and scale-Level measurement properties were computed. RESULTS. Infernal consistency reliability for the Total Scale Score (alpha = 0.88 child, 0.90 parent report), Physical Health Summary Score (alpha = 0.80 child, 0.88 parent), and Psychosocial Health Summary Score (alpha = 0.83 child, 0.86 parent) were acceptable for group comparisons. Validity was demonstrated using the known-groups method, correlations with indicators of morbidity and illness burden, and factor analysis. The PedsQL distinguished between healthy children and pediatric patients with acute or chronic health conditions, was related to indicators of morbidity and illness burden, and displayed a factor-derived solution largely consistent with the a priori conceptually-derived scales. CONCLUSION. The results demonstrate the reliabiity and validity of the PedsQL 4.0 Generic Care Scales. The PedsQL 4.0 Generic Core Scales may be applicable in clinical trials, research, clinical practice, school health settings, and community populations. AN - WOS:000170238200006 AU - Varni, J. W. AU - Seid, M. AU - Kurtin, P. S. DA - Aug DO - 10.1097/00005650-200108000-00006 IS - 8 N1 - Varni, JW Seid, M Kurtin, PS Fahimifar, Sepideh/M-5303-2019 PY - 2001 SN - 0025-7079 SP - 800-812 ST - PedsQL (TM) 4.0: Reliability and validity of the pediatric quality of life Inventory (TM) Version 4.0 generic core scales in healthy and patient populations T2 - Medical Care TI - PedsQL (TM) 4.0: Reliability and validity of the pediatric quality of life Inventory (TM) Version 4.0 generic core scales in healthy and patient populations UR - ://WOS:000170238200006 VL - 39 ID - 2847 ER - TY - JOUR AB - OBJECTIVE: To study the frequency of borderline mental disorders in children of secondary general education schools. MATERIAL AND METHODS: We examined 1013 male and female schoolchildren, aged 12-14 and 15-17 years. In the first stage, the they completed a screening questionnaire to estimate the presence of a range of psychosomatic syndromes. An analysis of medical history and clinical examination were performed as well. The second stage included medical examination using DAWBA for the children with total scores on The Strengths and Difficulty questionnaire ≥ 16; with the score ≥ 6 on the emotional scale and with the score ≤ 5 on the social scale. RESULTS AND CONCLUSION: Generalized anxiety and depression were recorded more often in girls than in boys. Every 4-th adolescent (26.1%), regardless of gender, had problems in communication with peers. At the same time, boys showed conduct disturbances more often (p = 0.005) than girls (23.3% and 16.3%, respectively). Depression syndrome was 6.1 times more frequent in adolescents of the older group as compared with younger children (p = 0.024). Depression was associated with chronic headache (68.6% of children, mostly in girls and in the older group), abdominal pain (37.3%, mostly in girls) and back pain (39.2%). AD - Research Institute for Medical Problems of the North, Krasnoyarsk. AN - 26288282 AU - Vasilieva, L. V. AU - Evert, L. S. AU - Tereshchenko, S. Y. AU - Gorbacheva, N. N. AU - Mochalkina, I. M. DO - 10.17116/jnevro20151154116-19 DP - NLM ET - 2015/08/20 IS - 4 KW - Abdominal Pain/epidemiology Adolescent Anxiety/*epidemiology Back Pain Borderline Personality Disorder/*epidemiology Child Depression/*epidemiology Female Headache Disorders/epidemiology Humans Male Russia Sex Factors Surveys and Questionnaires LA - rus N1 - Vasilieva, L V Evert, L S Tereshchenko, S Yu Gorbacheva, N N Mochalkina, I M English Abstract Journal Article Russia (Federation) Zh Nevrol Psikhiatr Im S S Korsakova. 2015;115(4):16-19. doi: 10.17116/jnevro20151154116-19. PY - 2015 SN - 1997-7298 (Print) 1997-7298 SP - 16-19 ST - [Borderline mental disorders in schoolchildren] T2 - Zh Nevrol Psikhiatr Im S S Korsakova TI - [Borderline mental disorders in schoolchildren] VL - 115 ID - 3185 ER - TY - JOUR AB - The purpose of this study was to evaluate the influence of stress and anxiety on the pressure pain threshold (PPT) of masticatory muscles and on the subjective pain report. Forty-five women, students, with mean age of 19.75 years, were divided into two groups: group 1:29 presenting with masticatory myofascial pain (MFP), according to the Research Diagnostic Criteria for Temporomandibular Disorders and group 2: 16 asymptomatic controls. An electronic algometer registered the pain thresholds on four different occasions throughout the academic year. To measure levels of stress, anxiety and pain, the Beck Anxiety Inventory, Lipp Stress Symptoms Inventory and Visual Analog Scale (VAS) were used. Three-way anova and Tukey's tests were used to verify differences in PPT between groups, times and sites. Levels of anxiety and VAS were compared using Mann-Whitney test, while Friedman's test was used for the within-groups comparison at different times (T1 to T4). The chi-squared and Cochran tests were performed to compare groups for the proportion of subjects with stress (alpha = 0.05). Differences in PPT recordings between time (P = 0.001) and sites (P < 0.001) were detected. Higher levels of anxiety and lower PPT figures were detected at T2 (academic examination) (P = 0.001). There was no difference between groups for anxiety and stress at any time (P > 0.05). The MFP group also has shown significant increase of VAS at the time of academic examination (P < 0.001). External stressors such as academic examinations have a potential impact on masticatory muscle tenderness, regardless of the presence of a previous condition such as masticatory myofascial pain. AD - Department of Prosthodontics, Bauru School of Dentistry, University of São Paulo, Bauru, Brazil. AN - 19210679 AU - Vedolin, G. M. AU - Lobato, V. V. AU - Conti, P. C. AU - Lauris, J. R. DA - May DO - 10.1111/j.1365-2842.2008.01932.x DP - NLM ET - 2009/02/13 IS - 5 KW - Adolescent Anxiety/*psychology Educational Measurement Female Humans Pain Measurement/instrumentation/methods Pain Threshold/*psychology Psychiatric Status Rating Scales Psychometrics Stress, Psychological/*psychology Temporomandibular Joint Dysfunction Syndrome/*psychology Young Adult LA - eng N1 - 1365-2842 Vedolin, G M Lobato, V V Conti, P C R Lauris, J R P Journal Article Research Support, Non-U.S. Gov't England J Oral Rehabil. 2009 May;36(5):313-21. doi: 10.1111/j.1365-2842.2008.01932.x. Epub 2009 Feb 6. PY - 2009 SN - 0305-182x SP - 313-21 ST - The impact of stress and anxiety on the pressure pain threshold of myofascial pain patients T2 - J Oral Rehabil TI - The impact of stress and anxiety on the pressure pain threshold of myofascial pain patients VL - 36 ID - 3715 ER - TY - JOUR AB - INTRODUCTION: Few pediatric studies classify the irritable bowel syndrome (IBS) subtypes. OBJECTIVE: To describe the characteristics and subtypes of IBS in children from Panama, Ecuador, El Salvador, Nicaragua and Mexico. MATERIAL AND METHODS: Prevalence study performed in children between 8 and 18 years of age with a diagnosis of IBS. The children answered the Questionnaire for Pediatric Gastrointestinal Symptoms Roma III for Schoolchildren and Adolescents (QPGS-III) to identify functional gastrointestinal disorders. Variables such as age and sex were taken into account. The subtypes of IBS were classified in IBS with constipation (IBS-c), with diarrhea (IBS-d), mixed (IBS-m) and without subtype (IBS-ss). Statistical analysis included measures of central tendency, two-tailed student t-test, chi-square test, and Fisher's exact test, with a significant p<0.05. RESULTS: We included 79 children (54.4% female, 12.1±2.1 years) presenting IBS-ss in 55.7%, IBS-c in 15.2%, IBS-m in 15.2% and SII-d in 13.9%. Severe pain predominated most of the day and with mucous stools; possible associations for IBS-d school and sex. CONCLUSION: After IBS-ss, the IBS-e, IBS-d and IBS-m are similar, being the possible risk factors for IBS-d, the public school and the female gender. AD - Universidad del Valle. Cali, Colombia. Hospital del Niño. Ciudad de Panamá, Panamá. Universidad Central del Ecuador. Quito, Ecuador; Universidad de la Frontera. Temuco, Chile. Departamento de Gastroenterología y Endoscopía, Hospital Nacional de Niños Benjamín Bloom. San Salvador, El Salvador. Hospital Nacional de Niños de Nicaragua. Managua, Nicaragua. Instituto Mexicano del Seguro Social. Monterrey, México; Hospital de Especialidades Clínica No. 25 IMSS. Monterrey, México. Servicios de Gastroenterología, Hospital del Niño y del Adolescente Morelense en Cuernavaca. Morelos, México. AN - 30118458 AU - Velasco-Benítez, C. A. AU - Chanís, R. AU - Játiva, E. AU - Zablah, R. AU - Mejía, M. AU - Rodriguez Reynosa, L. AU - Leyva Jimenez, S. A. DA - Apr-Jun DP - NLM ET - 2018/08/18 IS - 2 KW - Adolescent Child Ecuador/epidemiology El Salvador/epidemiology Female Humans Irritable Bowel Syndrome/*classification/diagnosis/*epidemiology Male Mexico/epidemiology Nicaragua/epidemiology Prevalence Risk Factors LA - spa N1 - 1609-722x Velasco-Benítez, Carlos Alberto Chanís, Ricardo Játiva, Edgar Zablah, Roberto Mejía, Milton Rodriguez Reynosa, Laura Leyva Jimenez, Sofia Araceli Journal Article Peru Rev Gastroenterol Peru. 2018 Apr-Jun;38(2):131-137. OP - Caracterización y subtipos del síndrome de intestino irritable en niños de Panamá, Ecuador, El Salvador, Nicaragua y México. PY - 2018 SN - 1022-5129 SP - 131-137 ST - [Irritable bowel syndrome subtypes and characteristics in children from Panama, Ecuador,El Salvador, Nicaragua and Mexico] T2 - Rev Gastroenterol Peru TI - [Irritable bowel syndrome subtypes and characteristics in children from Panama, Ecuador,El Salvador, Nicaragua and Mexico] VL - 38 ID - 3825 ER - TY - JOUR AB - Introduction: There are few studies on overlapping Functional Gastrointestinal Disorders (FGIDs). Objective: To describe the prevalence and possible risk factors in Latin American children (Latam) to present overlapping FGIDs. Patients and Method: Prevalence study in Latam schoolchildren between 8-18 years of age. Sociodemographic variables were included; the Rome III Criteria in Spanish were used, and overlapping FGIDs were considered when two, three or four and more FGIDs were presented in the same child. The statistical analysis included Student's T-test, chi-square test, Fisher's exact test, univariate and multivariate analysis, and calculation of ORs and 95% CI, being considered a significant p < 0.05. Results: 6,193 Latam children were analyzed (11.8 +/- 2.2 years, 62.2% between 8-12 years of age, 50.4% girls, 68.0% public school), and 23.4% with a diagnosis of some kind of FGIDs. There was overlap of FGIDs in the same child, in 8.4% (5.5% with 2 FGIDs, 2.1% with 3 FGIDs and 0.9% with 4 or more FGIDs), the main overlaps were irritable bowel syndrome (IBS) + functional abdominal pain (FAP) (2.6%), and IBS + FAP + functional constipation (1.1%). There was predominance of the female gender. Conclusion: There is a low prevalence of overlapping FGIDs in Latam schoolchildren and adolescents, with a predominance in females and of very variable presentation. AN - WOS:000458428000001 AU - Velasco-Benitez, C. A. AU - Ramirez-Hernandez, C. R. AU - Moreno-Gomez, J. E. AU - Jativa-Marino, E. AU - Zablah, R. AU - Rodriguez-Reynosa, L. L. AU - Leyva-Jimenez, S. A. AU - Chanish, R. AU - Mejia-Castro, M. DA - Dec IS - 6 N1 - Alberto Velasco-Benitez, Carlos Rossy Ramirez-Hernandez, Carmen Enrique Moreno-Gomez, Jairo Jativa-Marino, Edgar Zablah, Roberto Leticia Rodriguez-Reynosa, Laura Araceli Leyva-Jimenez, Sofia Chanish, Ricardo Mejia-Castro, Milton 0717-6228 PY - 2018 SN - 0370-4106 ST - Overlapping of functional gastrointestinal disorders in latinamerican schoolchildren and adolescents T2 - Revista Chilena De Pediatria-Chile TI - Overlapping of functional gastrointestinal disorders in latinamerican schoolchildren and adolescents UR - ://WOS:000458428000001 VL - 89 ID - 1977 ER - TY - JOUR AB - Introduction: Although results show an association between the presence of generalised joint hypermobility (GJH) and functional gastrointestinal disorders (FGIDs) in children, they are limited and controversial. Objective: To determine the association between GJH and FGIDs and the search for risk factors for GJH in girls from a Public Educational Institution of Tulua, Colombia. Patients and methods: The students completed the Rome IV Questionnaire to identify FGIDs. Each girl with a diagnosis of some FGIDs was matched with a healthy control of the same age. Joint laxity was assessed according to the Beighton score and was considered as GJH when it was >= 4. The prevalence of GJH was compared in girls with and without FGIDs. Results: Out of a total of 921 girls between 10 and 18 years of age that participated in the study, 219 (23.8%) of them had some FGIDs. The analysis was performed on a total of 169 girls with FGIDs and 169 healthy control girls. There were no significant differences in GJH between girls with and without a diagnosis of some FGIDs (OR=1.12: 95% CI; 0.71-1.77, P=.5838), nor were there any risk factors. Conclusion: In this study, no relationship or any risk factor was found between GJH and the presence of FGIDs. (C) 2019 Asociacion Espanola de Pediatria. Published by Elsevier Espana, S.L.U. AN - WOS:000500759500007 AU - Velasco-Benitez, C. A. AU - Ruiz-Extremera, A. AU - Saps, M. DA - Dec DO - 10.1016/j.anpedi.2019.04.006 IS - 6 N1 - Alberto Velasco-Benitez, Carlos Ruiz-Extremera, Angeles Saps, Miguel Ruiz-Extremera, Angeles o Angela/0000-0001-7978-1708 1696-4608 PY - 2019 SN - 1695-4033 SP - 401-407 ST - Case-Control Study On Generalised Joint Hypermobility In Schoolchildren With Functional Gastrointestinal Disorders According To Rome IV Criteria In Spanish T2 - Anales De Pediatria TI - Case-Control Study On Generalised Joint Hypermobility In Schoolchildren With Functional Gastrointestinal Disorders According To Rome IV Criteria In Spanish UR - ://WOS:000500759500007 VL - 91 ID - 1867 ER - TY - JOUR AB - Recurrent abdominal pain (RAP) is associated with increased health care visits and school absences. In adults suffering from functional pain, psychosocial factors determine illness behavior and we aimed to investigate its role among children. A community sample of 40 RAP consulters, 41 RAP nonconsulters, and 36 pain-free controls and their mothers completed questionnaires on GI and non-GI symptoms, school absences, psychological symptoms, coping, self-esteem, and behavioral and cognitive responses to RAP. T-tests showed significant differences between RAP and controls in (1) GI and non-GI symptoms and school absences, (2) child distress and passive coping, and (3) mother's IBS severity, somatization, and fears about RAP. RAP consulters reported the same levels of GI symptoms and psychological distress as nonconsulters but missed significantly more school and their mothers reported more fears about RAP. Severity of symptoms and psychological distress did not predict consulting behavior. Only maternal fears about abdominal symptoms differentiated consulters from nonconsulters. AN - WOS:000234602300036 AU - Venepalli, N. K. AU - Van Tilburg, M. A. L. AU - Whitehead, W. E. DA - Jan DO - 10.1007/s10620-006-3107-1 IS - 1 N1 - Venepalli, NK Van Tilburg, MAL Whitehead, WE van tilburg, miranda/0000-0002-0504-9829 1573-2568 PY - 2006 SN - 0163-2116 SP - 192-201 ST - Recurrent abdominal pain: What determines medical consulting behavior? T2 - Digestive Diseases and Sciences TI - Recurrent abdominal pain: What determines medical consulting behavior? UR - ://WOS:000234602300036 VL - 51 ID - 2748 ER - TY - CHAP AB - Sickle cell disease, the most common hemoglobin disorder, affects major organ systems with symptoms of pain, anemia and a multitude of chronic conditions. For adolescents, the disease adversely affects school attendance, academic progress and social activity. To effectively study the relationship among school attendance and other factors like demographics and academic performance, studies have relied on self-reporting and school records, all of which have some bias. In this study we design and prototype a system, called SickleSAM (Sickle cell School attendance and Activity Monitoring system), for automatically monitoring school attendance and daily activity of adolescents with sickle cell disease. SickleSAM intends to remove human bias and inaccuracies. The system uses built-in GPS to collect data which will be recorded into a cloud database using Short Messaging Service technology. SickleSAM is developed by Georgia Institute of Technology in conjunction with Children's Healthcare of Atlanta (CHOA). System effectiveness is being evaluated using a trial of 10 adolescents with the disease. AN - WOS:000313296502169 AU - Venugopalan, J. AU - Brown, C. AU - Cheng, C. W. AU - Stokes, T. H. AU - Wang, M. D. AU - Ieee N1 - Venugopalan, Janani Brown, Clark Cheng, Chihwen Stokes, Todd H. Wang, May D. Embc 34th Annual International Conference of the IEEE Engineering-in-Medicine-and-Biology-Society (EMBS) Aug 28-sep 01, 2012 San Diego, CA IEEE, Engn Med & Biol Soc (EMBS), CAS, SMC, PubMed, MEDLINE Wang, May Dongmei/AAF-2065-2021 Wang, May Dongmei/0000-0003-3961-3608 1557-170x PY - 2012 SN - 978-1-4577-1787-1 SP - 2456-2459 ST - Activity and School Attendance Monitoring System for Adolescents with Sickle Cell Disease T2 - 2012 Annual International Conference of the Ieee Engineering in Medicine and Biology Society T3 - IEEE Engineering in Medicine and Biology Society Conference Proceedings TI - Activity and School Attendance Monitoring System for Adolescents with Sickle Cell Disease UR - ://WOS:000313296502169 ID - 2452 ER - TY - JOUR AB - Objective To ascertain whether the frequency of pelvic pain recurrence is reduced and time to symptoms recurrence is prolonged in women with symptomatic endometriosis undergoing conservative surgery and post-operative hormonal therapy compared with women treated with surgery only. Pregnancy rates and time to conception in women wanting children were also evaluated. Design A multicentre, prospective, randomised controlled study. Setting Nineteen Italian academic departments and teaching hospitals specialising in reparative and reconstructive surgery. Population A total of 269 women undergoing conservative surgery for mild to severe symptomatic endometriosis. Methods After surgery the women were assigned to treatment with subcutaneous goserelin depot injections for six months or to expectant management. Dysmenorrhoea, deep dyspareunia, nonmenstrual pain and general discomfort were graded according to a verbal rating scale from 0 (absent) to 3 (severe) and the scores summed to give a total symptoms score. Only patients with at least one preoperative moderate or severe symptom were enrolled. The women were evaluated regularly for two years. Main outcome measures Post-operative pain recurrences (total symptoms scores greater than or equal to 5), time to recurrence, pregnancy rates and time to conception in the two study groups. Results At one- and two-year follow up visits, 14/107 (13.1%) and 19/81(23.5%) patients had moderate or severe symptoms recurrence in the goserelin group compared with, respectively, 22/103 (21.4%) and 27/74 (36.5%) in the expectant management group (P = 0.143 at 1 year and 0.082 at 2 years). Time to symptoms recurrence was significantly longer in the goserelin group according to survival analysis (Wilcoxon test, P = 0.041). Among women wanting children, few conceptions occurred in both the goserelin (8/69, 11.6%) and the expectant management group (14/76, 18.4%). There was no significant difference at survival analysis (Wilcoxon test, P = 0.427). Conclusion Post-operative treatment with goserelin significantly prolonged the pain-free interval after conservative surgery for symptomatic endometriosis and did not influence reproductive prognosis. AN - WOS:000081320500011 AU - Vercellini, P. AU - Crosignani, P. G. AU - Fadini, R. AU - Radici, E. AU - Belloni, C. AU - Sismondi, P. DA - Jul DO - 10.1111/j.1471-0528.1999.tb08366.x IS - 7 N1 - Vercellini, P Crosignani, PG Fadini, R Radici, E Belloni, C Sismondi, P Vercellini, Paolo/K-5295-2016 Vercellini, Paolo/0000-0003-4195-0996; Sismondi, Piero/0000-0002-2505-5716 PY - 1999 SN - 0306-5456 SP - 672-677 ST - A gonadotrophin-releasing hormone agonist compared with expectant management after conservative surgery for symptomatic endometriosis T2 - British Journal of Obstetrics and Gynaecology TI - A gonadotrophin-releasing hormone agonist compared with expectant management after conservative surgery for symptomatic endometriosis UR - ://WOS:000081320500011 VL - 106 ID - 2879 ER - TY - JOUR AB - Distraction is an intuitive way of coping with pain and is often used in children's pain treatment programs. However, empirical evidence concerning the effectiveness of distraction is equivocal. One potential explanation might be that distraction does not work for everyone in every situation. In the current series of studies, we examined the role of pain catastrophizing as an influencing factor of distraction effectiveness. In the first study, we investigated the use of pain coping strategies (including distraction) in schoolchildren (N = 828, aged 8-18 years) by means of a questionnaire. Results indicated that children with higher levels of pain catastrophizing reported using less distraction strategies in daily life than children with lower levels of pain catastrophizing. In the second study, a subsample (N = 81, aged 9-18 years) performed a painful cold pressor task (CPT) (12 °C). Participants were randomly assigned to a distraction group, in which an attention-demanding tone-detection task was performed during the CPT, or a control group, in which no distraction task was performed. Results showed that participants in the distraction group were engaged in the distraction task, and reported to have paid less attention to pain than participants in the control group. However, distraction was ineffective in reducing cold pressor pain, and even intensified the pain experience in high catastrophizing children. Caution may be warranted in using distraction as a 'one size fits all' method, especially in high catastrophizing children. AD - Department of Experimental-Clinical and Health Psychology, Ghent University, Belgium. kat.verhoeven@ugent.be AN - 22323378 AU - Verhoeven, K. AU - Goubert, L. AU - Jaaniste, T. AU - Van Ryckeghem, D. M. AU - Crombez, G. DA - Feb DO - 10.1016/j.ejpain.2011.06.015 DP - NLM ET - 2012/02/11 IS - 2 KW - Adaptation, Psychological/*physiology Adolescent Analgesia/*psychology Catastrophization/physiopathology/*psychology Child Chronic Pain/physiopathology/*psychology/*therapy Female Humans Male Random Allocation LA - eng N1 - 1532-2149 Verhoeven, K Goubert, L Jaaniste, T Van Ryckeghem, D M L Crombez, G Journal Article Research Support, Non-U.S. Gov't England Eur J Pain. 2012 Feb;16(2):256-67. doi: 10.1016/j.ejpain.2011.06.015. PY - 2012 SN - 1090-3801 SP - 256-67 ST - Pain catastrophizing influences the use and the effectiveness of distraction in schoolchildren T2 - Eur J Pain TI - Pain catastrophizing influences the use and the effectiveness of distraction in schoolchildren VL - 16 ID - 3213 ER - TY - JOUR AB - The present study examined existing communal and operant accounts of children's pain behavior by looking at the impact of parental presence and parental attention upon children's pain expression as a function of child pain catastrophizing. Participants were 38 school children and 1 of their parents. Children completed a cold pressor pain task (CPT) twice, first when told that no one was observing (alone condition) and subsequently when told that they were being observed by their parent (parent-present condition). A 3-minute parent-child interaction occurred between the 2 CPT immersions, allowing measurement of parental attention to their child's pain (ie, parental pain-attending talk vs non-pain-attending talk). Findings showed that child pain catastrophizing moderated the impact of parental presence upon facial displays of pain. Specifically, low-catastrophizing children expressed more pain in the presence of their parent, whereas high-catastrophizing children showed equally pronounced pain expression when alone or in the presence of a parent. Furthermore, children's catastrophizing moderated the impact of parental attention upon facial displays and self-reports of pain; higher levels of parental nonpain talk were associated with increased facial expression and self-reports of pain among high-catastrophizing children; for low-catastrophizing children, facial and self-report of pain was independent of parental attention to pain. The findings are discussed in terms of possible mechanisms that may drive and maintain pain expression in high-catastrophizing children, as well as potential limitations of traditional theories in explaining pediatric pain expression. AU - Vervoort, Tine AU - Caes, Line AU - Trost, Zina AU - Sullivan, Michael AU - Vangronsveld, Karoline AU - Goubert, Liesbet DA - 2011/07// DO - 10.1016/j.pain.2011.02.048 DP - PubMed IS - 7 J2 - Pain KW - Analysis of Variance Attention Catastrophization Cold Temperature Facial Pain Female Humans Male Observation Pain Measurement Parent-Child Relations Parents Pressure Regression Analysis Self Report LA - eng PY - 2011 SN - 1872-6623 SP - 1591-1599 ST - Social modulation of facial pain display in high-catastrophizing children T2 - Pain TI - Social modulation of facial pain display in high-catastrophizing children: an observational study in schoolchildren and their parents UR - http://www.ncbi.nlm.nih.gov/pubmed/21459512 VL - 152 ID - 99 ER - TY - JOUR AB - We investigated the role of the child's pain catastrophizing in explaining (1) children's self-reported tendency to verbally share their pain experience with others and (2) different dimensions of pain expression, as described by the mother and the father, including non-verbal and verbal communicative pain behaviour and protective pain behaviour. Participants were school children, children with chronic or recurrent pain, and their parents. The results showed that: (1) Pain catastrophizing was associated with children's greater self-acknowledged tendency to verbally share their pain experience with others. (2) Mothers and fathers perceived highly catastrophizing children to be more communicative about their pain. (3) The role of pain catastrophizing in the child's verbal sharing of pain experiences and in explaining expressive behaviour as rated by parents did not differ between the school children and children with recurrent and chronic pain. (4) Nevertheless, findings indicated marked differences between school children and the clinical sample. Children of the clinical sample experienced more severe pain, more pain catastrophizing, more protective pain behaviour, but less verbal communications about their pain. These results further corroborate the position that catastrophic thoughts about pain have interpersonal consequences. Findings are discussed in terms of the possible functions and effects upon others of pain catastrophizing and associated categories of pain behaviour. AU - Vervoort, T. AU - Craig, K. D. AU - Goubert, L. AU - Dehoorne, J. AU - Joos, R. AU - Matthys, D. AU - Buysse, A. AU - Crombez, G. DA - 2008/01// DO - 10.1016/j.pain.2007.03.038 DP - PubMed IS - 1-2 J2 - Pain KW - Adolescent Adult Child Communication Cross-Sectional Studies Emotions Female Humans Male Middle Aged Pain Pain Measurement Students LA - eng PY - 2008 SN - 1872-6623 SP - 59-68 ST - Expressive dimensions of pain catastrophizing T2 - Pain TI - Expressive dimensions of pain catastrophizing: a comparative analysis of school children and children with clinical pain UR - http://www.ncbi.nlm.nih.gov/pubmed/17493753 VL - 134 ID - 118 ER - TY - JOUR AB - Catastrophic thinking about pain has been identified as an important determinant of adjustment to pain, in both adults and children. No study has investigated the prospective and unique role of catastrophizing in explaining later pain and disability in children. The aim of the present study was to investigate the prospective roles of catastrophic thinking about pain, pain intensity, and trait anxiety and their putative relationship with pain and disability tested 6 months later. Participants were 323 schoolchildren. Analyses revealed that the child's pain catastrophizing at baseline had a small but unique contribution to the prediction of pain and disability 6 months later, even when controlling for the initial pain and disability levels. In line with expectations, moderation analyses revealed that the effects of catastrophizing upon pain and disability at follow-up were only true for those children reporting low levels intensity of pain at baseline. The variability in disability and pain complaint could not be explained by trait anxiety. instead anxious disposition might be best conceived of as a precursor of catastrophizing in children; i.e. children with higher levels of trait anxiety at baseline were more inclined to report higher levels of catastrophizing at follow-up. The findings are discussed in terms of potential mechanisms through which catastrophizing might exert its negative impact upon pain and disability outcomes in children. (C) 2009 European Federation of International Association for the Study of Pain Chapters. Published by Elsevier Ltd. All rights reserved. AN - WOS:000274481800015 AU - Vervoort, T. AU - Eccleston, C. AU - Goubert, L. AU - Buysse, A. AU - Crombez, G. DA - Jan DO - 10.1016/j.ejpain.2009.03.001 IS - 1 N1 - Vervoort, T. Eccleston, C. Goubert, L. Buysse, A. Crombez, G. Crombez, Geert/O-2268-2013; Goubert, Liesbet/J-9607-2012 Crombez, Geert/0000-0002-4744-8561; Goubert, Liesbet/0000-0002-7657-5148; Vervoort, Tine/0000-0002-9601-8525; Eccleston, Christopher/0000-0003-0698-1543 PY - 2010 SN - 1090-3801 SP - 90-96 ST - Children's catastrophic thinking about their pain predicts pain and disability 6 months later T2 - European Journal of Pain TI - Children's catastrophic thinking about their pain predicts pain and disability 6 months later UR - ://WOS:000274481800015 VL - 14 ID - 2573 ER - TY - JOUR AB - OBJECTIVE: To investigate the value of pain catastrophizing in explaining pain, disability, and somatic complaints, beyond negative affectivity (NA). METHOD: Two cross-sectional studies, one in a sample of school children (n = 193) and a second in a clinical sample of children with recurrent or chronic pain (n = 43), were conducted. In both studies, measures of pain catastrophizing and NA were examined for their ability to explain pain, disability, and somatic complaints. RESULTS: In both studies, pain catastrophizing significantly accounted for the variance of pain, disability, and somatic complaints, beyond the effects of age, sex, and NA. Furthermore, pain catastrophizing significantly mediated the relationship between NA and somatic complaints in both studies and between NA and functional disability in study 1. CONCLUSIONS: Results suggest the importance of assessing for pain catastrophizing in children. Pain catastrophizing is further discussed in terms of communicating distress to significant others. AD - Department of Experimental-Clinical and Health Psychology, Ghent University, Henri Dunantlaan 2, B-9000, Ghent, Belgium. tine.vervoort@ugent.be AN - 16093515 AU - Vervoort, T. AU - Goubert, L. AU - Eccleston, C. AU - Bijttebier, P. AU - Crombez, G. DA - Aug DO - 10.1093/jpepsy/jsj059 DP - NLM ET - 2005/08/12 IS - 7 KW - Child Chronic Disease *Disability Evaluation Female Humans Male Pain/*diagnosis/*psychology Pain Measurement Predictive Value of Tests Severity of Illness Index Somatoform Disorders/*diagnosis/*epidemiology *Thinking LA - eng N1 - Vervoort, Tine Goubert, Liesbet Eccleston, Christopher Bijttebier, Patricia Crombez, Geert Journal Article United States J Pediatr Psychol. 2006 Aug;31(7):674-83. doi: 10.1093/jpepsy/jsj059. Epub 2005 Aug 10. PY - 2006 SN - 0146-8693 (Print) 0146-8693 SP - 674-83 ST - Catastrophic thinking about pain is independently associated with pain severity, disability, and somatic complaints in school children and children with chronic pain T2 - J Pediatr Psychol TI - Catastrophic thinking about pain is independently associated with pain severity, disability, and somatic complaints in school children and children with chronic pain VL - 31 ID - 3303 ER - TY - JOUR AB - The current cross-sectional study examined child and adolescent pain severity in relation to various domains of school functioning and, in line with self-determination theory, the potentially protective role of perceived teacher support of child/adolescent autonomy and competence. Data from a large representative sample of Flemish school children and adolescents (N=10650; 50.8% boys; age range 10-21years; mean age=14.33) was collected as part of the World Health Organization (WHO) collaborative Health Behaviour in School-Aged Children (HBSC) survey. Child/adolescent pain severity was graded based on a pediatric pain classification system adapted from that of Von Korff et al. The current study thus provided insight regarding the prevalence of pain among Flemish children/adolescents and, extending the limitations of existing literature, examined the specific role of pain severity across various domains of school functioning. Findings indicated that a sizeable proportion of children reported moderate to severe pain problems (ie, about 14% of children and adolescents were classified in the highest pain grades: ie, grade III or IV). Furthermore, higher pain grades were associated with poorer outcomes across all indices of school functioning (ie, school absenteeism, school-related pressure and satisfaction, and bullying experiences), with the exception of academic performance. However, the association between pain grade and school absenteeism was less pronounced when children perceived their teachers to be highly supportive of competence and autonomy. Furthermore, teacher support of competence appeared to buffer against the harmful effects of severe pain upon instances of bullying experiences at school. Future research directions and implications for school-based interventions are discussed. AU - Vervoort, Tine AU - Logan, Deirdre E. AU - Goubert, Liesbet AU - De Clercq, Bart AU - Hublet, Anne DA - 2014/06// DO - 10.1016/j.pain.2014.02.021 DP - PubMed IS - 6 J2 - Pain KW - Adolescent Child Children Cross-Sectional Studies Faculty Female Humans Male Pain Pain severity Prevalence School functioning Schools Self Report Self-determination theory Severity of Illness Index Social Support Support Teacher Young Adult LA - eng PY - 2014 SN - 1872-6623 SP - 1118-1127 ST - Severity of pediatric pain in relation to school-related functioning and teacher support T2 - Pain TI - Severity of pediatric pain in relation to school-related functioning and teacher support: an epidemiological study among school-aged children and adolescents UR - http://www.ncbi.nlm.nih.gov/pubmed/24631587 VL - 155 ID - 78 ER - TY - JOUR AB - BACKGROUND: Pediatric chronic pain is very common and results in significant health care costs. Pediatric chronic pain is both an individual and a public health concern. The primary objective of this study was to generate a descriptive clinical profile of the patients referred to an anesthesiology-based pediatric chronic pain medicine program. This patient profile was intended to serve as a surrogate for a more formal population needs assessment. METHODS: A quantitative observational study design was applied. The independent study variables included the primary pain-related diagnosis, duration of pain symptoms, patient age, patient sex, insurance status, an intact biological family unit, fulltime school attendance, home schooling, and comorbid depression and/or anxiety. Using a series of previously well-vatidated measurement instruments, the dependent study variables included self-reported chronic pain intensity, self-reported and parent proxy-reported health-related quality of life, adverse family impact, and parental satisfaction. Study data collection occurred at the time of the first visit to the pediatric chronic pain medicine clinic but before interacting with any health care provider. RESULTS: The enrolled patients (n = 100) were predominantly adolescent females, whose chronic pain had persisted for >1 yr and whose pain was frequently accompanied by clinically significant anxiety and depression. As compared with national and state norms, a significantly disproportionate percentage had a nonintact biological family unit (P < 0.001), was not attending school fulltime (P < 0.001), and was intentionally being home-schooled (P < 0.001). Ninety-five percent of the present cohort of patients had previously been under the care of at least one other subspecialist for their chronic pain condition. The mean initial patient self-reported and initial parent proxy-reported health-related quality of life scores (PedsQL Total Score) were also significantly lower than the PedsQL Total Score values previously observed in pediatric rheumatology patients (P < 0.0001), pediatric migraine patients (P < 0.0001), and pediatric cancer patients (P < 0.0001). CONCLUSIONS: Pediatric chronic pain patients previously under the care of another subspecialist and subsequently referred to an anesthesiology-based pediatric chronic pain medicine program seemed to be experiencing significantly worse health-related quality of life. The routine assessment of chronic pain-related pediatric health-related quality of life seems feasible and worthwhile. Attention also needs to be focused on consistently addressing the strength of a patient's coping mechanisms, the presence of pain-promoting versus pain-reducing parental behaviors, and preexisting parental pain and disability. AN - WOS:000253393900015 AU - Vetter, T. R. DA - Mar DO - 10.1213/ane.0b013e3181609483 IS - 3 N1 - Vetter, Thomas R. Annual Meeting of the American-Society-of-Anesthesiologists Oct 13-17, 2007 San Francisco, CA Amer Soc Anesthesiologists PY - 2008 SN - 0003-2999 SP - 786-794 ST - A clinical profile of a cohort of patients referred to an anesthesiology-based pediatric chronic pain medicine program T2 - Anesthesia and Analgesia TI - A clinical profile of a cohort of patients referred to an anesthesiology-based pediatric chronic pain medicine program UR - ://WOS:000253393900015 VL - 106 ID - 2656 ER - TY - JOUR AB - BACKGROUND: It has been estimated that about 10 per cent of children between 6 and 20 years of age suffer from migraine, and that children with migraine lose one and a half weeks more schooling per year than their peers. Prophylactic drugs can be prescribed when children suffer from frequent or disabling headaches. OBJECTIVES: To describe and assess the evidence from controlled trials on the efficacy and tolerability of pharmacological agents taken on a regular basis to prevent the occurrence of migraine attacks and/or reduce the intensity of such attacks in children with migraine. SEARCH METHODS: The Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, and EMBASE were searched from 1966 through 2002. Additional strategies for identifying trials included searching the reference lists of review articles and included studies and searching books related to headache. SELECTION CRITERIA: Prospective randomised controlled trials (RCTs) of self‐ or parent‐administered drug treatments in children (under 18 years of age) who had received a diagnosis of migraine were included. DATA COLLECTION AND ANALYSIS: Two investigators extracted, assessed, and coded separately all data for each study, using a form that was designed specifically for the review. Any disagreement was resolved by discussion. Headache frequency standardised over 28 days was used as the primary outcome measure. Headache intensity, headache duration, amount of symptomatic treatment used, and headache indices were used as secondary outcome measures. Data were extracted from both parallel‐group and crossover trials. Continuous and dichotomous data were used to calculate standardised mean differences (SMDs) and odds ratios (ORs), respectively. Numbers‐needed‐to‐treat (NNTs) and numbers‐needed‐to‐harm (NNHs) were also calculated. MAIN RESULTS: Thirty‐eight studies were selected. Eighteen were excluded. Eleven preventive drugs were compared with placebo in a total of 15 studies. Drug‐drug comparisons were made in just six studies. For only four drugs (L‐5‐hydroxytryptophan [L‐5HTP], flunarizine, clonidine, and propranolol) were two or more studies selected. For only six drugs (trazodone, L‐5HTP, propranolol, flunarizine, papaverine, and nimodipine) were data reported for effect on frequency. For no individual drug were comparable data reported in more than one study, thus meta‐analysis was not possible. Two placebo‐controlled studies showed a beneficial effect on the primary outcome measure, headache frequency. They were for the drugs propranolol and flunarizine. The propranolol study reported a dichotomous outcome (proportion of children responding), and it was possible to calculate a number‐needed‐to‐treat to produce a two‐thirds reduction in headache frequency (NNT = 1.5, 95%CI 1.15 to 2.1). The flunarizine study produced a SMD of 1.51 (95% confidence interval, ‐2.21 to ‐0.82), which was statistically significant in favour of flunarizine (p < 0.001). Nimodipine, timolol, papaverine, pizotifen, trazodone, L‐5HTP, clonidine, metoclopramide, and domperidone showed no efficacy in reduction of frequency of attacks. The available studies on cyproheptadine, phenobarbitone, phenytoin, amitriptyline, carbamazepine, metoprolol, and piracetam were excluded for various reasons. AUTHORS' CONCLUSIONS: Only one study each for propranolol and flunarizine were identified showing efficacy of these drugs as prophylactics of paediatric migraine. Nimodipine, timolol, papaverine, pizotifen, trazodone, L‐5HTP, clonidine, metoclopramide, and domperidone showed no efficacy in reduction of frequency of attacks. Available studies on other commonly used drugs failed to meet our inclusion criteria. The quality of evidence available for the use of drug prophylaxis in paediatric migraine was poor. Studies were generally small, with no planning of sample size, so that for many drugs, despite the negative findings of this review, we do not have conclusive evidence of 'no effect'. There is a clear and urgent need for methodologically sound RCTs for the use of prophylactic drugs in paediatric migraine, starting with propranolol. These studies need to be adequately powered to investigate meaningful reductions in pain and suffering from a patient's perspective. This systematic review evaluated studies of drug treatments for preventing migraine headaches in children. Twenty randomised controlled trials were included. Two studies showed a beneficial effect on the primary outcome measure, headache frequency. These were trials of the drugs propranolol and flunarizine. Nimodipine, timolol, papaverine, pizotifen, trazodone, L‐5‐hydroxytryptophan (L‐5HTP), clonidine, metoclopramide, and domperidone showed no efficacy in reduction of frequency of attacks. Available studies on other commonly used drugs failed to meet our inclusion criteria. The quality of evidence available for the use of drug prophylaxis in paediatric migraine is poor. Studies have generally been small, with no planning of sample size, so that for many drugs, despite the negative findings of this review, we do not have conclusive evidence of 'no effect'. More research is needed on this important topic. eng AD - Maternal and Fetal Health Research Group, Neonatal Medical Unit, 5th Floor, St Mary's Hospital, Whitworth Park, Manchester, UK, M13 0JH. AN - 25019292 AU - Victor, S. AU - Ryan, S. C2 - PMC6464504 DA - Jul 11 DO - 10.1002/14651858.CD002761.pub2 DP - NLM ET - 2014/07/16 IS - 7 KW - Adolescent Child Humans Migraine Disorders/*drug therapy/prevention & control Randomized Controlled Trials as Topic LA - eng N1 - 1469-493x Victor, Suresh Ryan, Steven Journal Article Research Support, Non-U.S. Gov't Review Systematic Review Cochrane Database Syst Rev. 2014 Jul 11;2014(7):CD002761. doi: 10.1002/14651858.CD002761.pub2. PY - 2014 SN - 1361-6137 SP - Cd002761 ST - WITHDRAWN: Drugs for preventing migraine headaches in children T2 - Cochrane Database Syst Rev TI - WITHDRAWN: Drugs for preventing migraine headaches in children VL - 2014 ID - 3219 ER - TY - JOUR AB - BACKGROUND: It has been estimated that about ten per cent of children between six and 20 years of age suffer from migraine. It is estimated that children with migraine lose one and a half weeks more schooling per year than their peers. Prophylactic drugs can be prescribed when children suffer from frequent or disabling headaches. OBJECTIVES: We aimed to describe and assess the evidence from controlled trials on the efficacy and tolerability of pharmacological agents taken on a regular basis to prevent the occurrence of migraine attacks and/or reduce the intensity of such attacks in children with migraine. SEARCH STRATEGY: The Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, and EMBASE were searched from 1966 through 2002. Additional strategies for identifying trials included searching the reference lists of review articles and included studies and searching books related to headache. SELECTION CRITERIA: Prospective randomised controlled trials (RCTs) of self- or parent-administered drug treatments in children (under 18 years of age) who had received a diagnosis of migraine were included. DATA COLLECTION AND ANALYSIS: Two investigators extracted, assessed, and coded separately all data for each study, using a form that was designed specifically for the review. Any disagreement was resolved by discussion. Headache frequency standardised over 28 days was used as the primary outcome measure. Headache intensity, headache duration, amount of symptomatic treatment used, and headache indices were used as secondary outcome measures. Data were extracted from both parallel-group and crossover trials. Continuous and dichotomous data were used to calculate standardised mean differences (SMDs) and odds ratios (ORs), respectively. Numbers-needed-to-treat (NNTs) and numbers-needed-to-harm (NNHs) were also calculated. MAIN RESULTS: Thirty-eight studies were selected. Eighteen were excluded. Eleven preventive drugs were compared with placebo in a total of 15 studies. Drug-drug comparisons were made in just six studies. For only four drugs (L-5-hydroxytryptophan [L-5HTP], flunarizine, clonidine, and propranolol) were two or more studies selected. For only six drugs (trazodone, L-5HTP, propranolol, flunarizine, papaverine, and nimodipine) were data reported for effect on frequency. For no individual drug were comparable data reported in more than one study, thus meta-analysis was not possible. Two placebo-controlled studies showed a beneficial effect on the primary outcome measure, headache frequency. They were for the drugs propranolol and flunarizine. The propranolol study reported a dichotomous outcome (proportion of children responding), and it was possible to calculate a number-needed-to-treat to produce a two-thirds reduction in headache frequency (NNT = 1.5, 95%CI 1.15 to 2.1). The flunarizine study produced a SMD of 1.51 (95% confidence interval, -2.21 to -0.82), which was statistically significant in favour of flunarizine (p < 0.001). Nimodipine, timolol, papaverine, pizotifen, trazodone, L-5HTP, clonidine, metoclopramide, and domperidone showed no efficacy in reduction of frequency of attacks. The available studies on cyproheptadine, phenobarbitone, phenytoin, amitriptyline, carbamazepine, metoprolol, and piracetam were excluded for various reasons. REVIEWER'S CONCLUSIONS: Only one study each for propranolol and flunarizine were identified showing efficacy of these drugs as prophylactics of paediatric migraine. Nimodipine, timolol, papaverine, pizotifen, trazodone, L-5HTP, clonidine, metoclopramide, and domperidone showed no efficacy in reduction of frequency of attacks. Available studies on other commonly used drugs failed to meet our inclusion criteria. The quality of evidence available for the use of drug prophylaxis in paediatric migraine was poor. Studies were generally small, with no planning of sample size, so that for many drugs, despite the negative findings of this review, we do not have conclusive evidence of 'no effect'. There is a clear and urgent need for methodologically sound RCTs for the use of pings of this review, we do not have conclusive evidence of 'no effect'. There is a clear and urgent need for methodologically sound RCTs for the use of prophylactic drugs in paediatric migraine, starting with propranolol. These studies need to be adequately powered to investigate meaningful reductions in pain and suffering from a patient's perspective. AN - 14583952 AU - Victor, S. AU - Ryan, S. W. DO - 10.1002/14651858.Cd002761 DP - NLM ET - 2003/10/30 IS - 4 KW - Adolescent Child Humans Migraine Disorders/*drug therapy/prevention & control Randomized Controlled Trials as Topic LA - eng N1 - 1469-493x Victor, S Ryan, S W Journal Article Review Systematic Review England Cochrane Database Syst Rev. 2003;(4):CD002761. doi: 10.1002/14651858.CD002761. PY - 2003 SN - 1361-6137 SP - Cd002761 ST - Drugs for preventing migraine headaches in children T2 - Cochrane Database Syst Rev TI - Drugs for preventing migraine headaches in children ID - 3234 ER - TY - JOUR AB - PURPOSE: Population based studies have demonstrated that children and adolescents often complain of low back pain. A group-randomized controlled trial was carried out to investigate the effects of a postural education program on school backpack habits related to low back pain in children aged 10-12 year. METHODS: The study sample included 137 children aged 10.7 years (SD = 0.672). Six classes from two primary schools were randomly allocated into experimental group (EG) (N = 63) or control group (CG) (N = 74). The EG received a postural education program over 6 weeks consisting of six sessions, while the CG followed the usual school curriculum. A questionnaire was fulfilled by the participants at pre-test, post-test, and 3 months after the intervention finished. The outcomes collected were: (1) try to load the minimum weight possible, (2) carry school backpack on two shoulders, (3) belief that school backpack weight does not affect to the back, and (4) the use of locker or something similar at school. A sum score was computed from the four items. RESULTS: Single healthy items mostly improved after the intervention and remained improved after 3-month follow-up in EG, while no substantial changes were observed in the CG. Healthy backpack use habits score was significantly increased at post-test compared to baseline in the EG (P < 0.000), and remained significantly increased after 3-month, compared to baseline (P = 0.001). No significant changes were observed in the CG (P > 0.2). CONCLUSIONS: The present study findings confirm that children are able to learn healthy backpack habits which might prevent future low back pain. AU - Vidal, Josep AU - Borràs, Pere A. AU - Ponseti, Francisco J. AU - Cantallops, Jaume AU - Ortega, Francisco B. AU - Palou, Pere DA - 2013/04// DO - 10.1007/s00586-012-2558-7 DP - PubMed IS - 4 J2 - Eur Spine J KW - Child Female Health Education Humans Incidence Low Back Pain Male Outcome Assessment, Health Care Posture Schools Spain Students Surveys and Questionnaires Weight-Bearing LA - eng PY - 2013 SN - 1432-0932 SP - 782-787 ST - Effects of a postural education program on school backpack habits related to low back pain in children T2 - European Spine Journal: Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society TI - Effects of a postural education program on school backpack habits related to low back pain in children UR - http://www.ncbi.nlm.nih.gov/pubmed/23143093 VL - 22 ID - 95 ER - TY - JOUR AN - WOS:000209928800594 AU - Vila, M. AU - Kramer, T. AU - Garralda, E. DA - Jun IS - 1 N1 - Vila, Mar Kramer, Tami Garralda, Elena 1435-165x S PY - 2011 SN - 1018-8827 SP - S194-S194 ST - Recurrent abdominal pains in British secondary school children: impairment and associations with psychological factors T2 - European Child & Adolescent Psychiatry TI - Recurrent abdominal pains in British secondary school children: impairment and associations with psychological factors UR - ://WOS:000209928800594 VL - 20 ID - 2492 ER - TY - JOUR AB - Objective To present normative and psychometric data on somatic symptoms using the Children's Somatization Inventory (CSI) in a nonclinical sample of British young people, and to assess associations with stress and functional impairment. Methods A total of 1,173 students (11- to 16-years old) completed the CSI and self-report psychopathology measures. Results The median CSI total score was 12 (5, 23). Headaches, feeling low in energy, sore muscles, faintness, and nausea were most frequent. Girls scored higher than boys, and respondents aged 13-14 years lower than younger children. The CSI showed good internal consistency and exploratory factor analysis yielded three factors: pain/weakness, gastrointestinal, and pseudoneurological. A quarter of respondents reported somatic symptoms were made worse by stress. CSI scores were moderately significantly correlated with impairment and emotional symptoms. Conclusions The CSI, complemented by information on functional impairment and stress is an appropriate measure of recent somatic symptoms and somatization risk in young people for use in the UK. AN - WOS:000269997800008 AU - Vila, M. AU - Kramer, T. AU - Hickey, N. AU - Dattani, M. AU - Jefferis, H. AU - Singh, M. AU - Garralda, M. E. DA - Oct DO - 10.1093/jpepsy/jsp005 IS - 9 N1 - Vila, Mar Kramer, Tami Hickey, Nicole Dattani, Meera Jefferis, Helen Singh, Mandeep Garralda, M. Elena 1465-735x PY - 2009 SN - 0146-8693 SP - 989-998 ST - Assessment of Somatic Symptoms in British Secondary School Children Using the Children's Somatization Inventory (CSI) T2 - Journal of Pediatric Psychology TI - Assessment of Somatic Symptoms in British Secondary School Children Using the Children's Somatization Inventory (CSI) UR - ://WOS:000269997800008 VL - 34 ID - 2588 ER - TY - JOUR AB - Background. Nonspecific back pain in children is nearly as common as in adults but is associated with a number of age-specific risk factors including female gender, a family history of low back pain, a high level of physical activity, and prolonged sitting. Objective. To investigate potential school-related risk factors for back pain in children, most notably schoolbag weight expressed as a percentage of body weight (relative schoolbag weight), whether the schoolbag is carried by hand or by a shoulder harness, how the child travels to and from school, and sitting positions. Patients and Methods. 123 eighth-graders, 58 girls and 65 boys, with a mean age of 14+/-0.6 years, completed an anonymous self-questionnaire during a school day involving six hours of classes. Their schoolbag was weighed on the same day. Results. Most respondents traveled to and from school in a vehicle (70%), made one trip in each direction each day (75%), and carried their schoolbag by the shoulder harness (92%). The prevalence of back pain on the study day was 27.6%, whereas the cumulative prevalence for the last 12 months was 82.9% with 16.3% of respondents reporting a single episode of pain, 57.7% recurrent pain, and 8.9% chronic pain. A need for a physician visit for back pain was reported in 18.7% of cases, and 14.6% of respondents had missed school and/or sporting activities because of back pain. Female gender was associated with current back pain (odds ratio [OR], 2.7: 95% confidence interval [CI], 1.2-6.1). A relative schoolbag weight of 20% or more was associated with a history of back pain (OR, 3.1; 95% CI, 1.0-9.2), and this effect was larger in children who traveled to and from school on foot and in those who carried their schoolbag in their hand. Sitting on the edge of the chair while completing the questionnaire was significantly associated with a history of a physician visit for back pain (OR, 3.1; 95% CI, 1.0-9.5). Neither handedness nor the position of the questionnaire on the table were significantly associated with back pain in our study population. Conclusions. The findings from this cross-sectional study indicate a need for a longitudinal prospective study designed to identify etiologic and prognostic factors of back pain in adolescents, with the goal of devising preventive strategies likely to reduce the risk of low back pain in adulthood. AN - WOS:000082854200004 AU - Viry, P. AU - Creveuil, C. AU - Marcelli, C. DA - Jul-Sep IS - 7-9 N1 - Viry, P Creveuil, C Marcelli, C CREVEUIL, Christian/L-7215-2015 CREVEUIL, Christian/0000-0002-5506-5296 PY - 1999 SN - 1169-8446 SP - 381-388 ST - Nonspecific back pain in children - A search for associated factors in 14-year-old schoolchildren T2 - Revue Du Rhumatisme TI - Nonspecific back pain in children - A search for associated factors in 14-year-old schoolchildren UR - ://WOS:000082854200004 VL - 66 ID - 2882 ER - TY - JOUR AB - STUDY OBJECTIVE: The primary goal of this study was to determine if the addition of clonidine to ropivacaine prolonged periumbilical numbness compared to ropivacaine alone in pediatric patients receiving ultrasound guided rectus sheath nerve blocks for laparoscopic appendectomy. The secondary goals were to evaluate differences in perioperative pain scores, analgesic consumption, sedation, anxiolysis, and hemodynamic effects from clonidine. DESIGN: This was a single center, randomized, double-blinded prospective study. SETTING: This study was conducted within the pediatric operating rooms at the Children's Hospital of Pittsburgh, a large university-based academic medical center. PATIENTS: Fifty pediatric patients (ages 10-17 years old) without pre-existing cognitive impairment, developmental delay or chronic pain undergoing laparoscopic appendectomy during weekday hours were enrolled and randomized to control versus intervention groups. INTERVENTION: Ultrasound guided rectus sheath nerve block injections were performed at the beginning of surgery with either ropivacaine 0.5% plus normal saline or ropivacaine 0.5% plus clonidine (2 mcg/kg, maximum of 100 mcg). MEASUREMENTS: The duration of periumbilical numbness, Numeric Pain Rating Scale scores, University of Michigan Sedation Scale, State-Trait Anxiety Inventory for Children, analgesic consumption, heart rate, blood pressure, and mean arterial pressures, were recorded for each patient at several time points in the perioperative setting. MAIN RESULTS: There were no significant differences in demographic characteristics between groups. The median duration of periumbilical numbness did not significantly differ between the ropivacaine only and the ropivacaine plus clonidine groups 540.0 minutes [360.0 -1015.0] (median [interquartile range (IQR)]) versus 823.5 minutes [509.5- 1080.0], p = 0.451. There were no significant differences in perioperative analgesic consumption, pain and anxiety scores, PACU sedation, or hemodynamic instability. CONCLUSIONS: The addition of clonidine did not significantly prolong rectus sheath nerve block duration and was well tolerated in pediatric patients. Perioperative analgesia, hemodynamics, anxiety, and PACU sedation did not differ between groups. TRIAL REGISTRATION: Clinical Trials NCT02439281. AD - UPMC Children's Hospital of Pittsburgh, Department of Anesthesiology and Perioperative Medicine, 4401 Penn Avenue, Pittsburgh, PA 15224, USA. Electronic address: visoium@upmc.edu. UPMC Children's Hospital of Pittsburgh, Department of Pediatric General and Thoracic Surgery, 4401 Penn Avenue, Pittsburgh, PA 15224, USA. UPMC Children's Hospital of Pittsburgh, Department of Anesthesiology and Perioperative Medicine, 4401 Penn Avenue, Pittsburgh, PA 15224, USA. AN - 33752119 AU - Visoiu, M. AU - Scholz, S. AU - Malek, M. M. AU - Carullo, P. C. DA - Aug DO - 10.1016/j.jclinane.2021.110254 DP - NLM ET - 2021/03/23 KW - Analgesia Anesthesia Clonidine Nerve blocks LA - eng N1 - 1873-4529 Visoiu, Mihaela Scholz, Stefan Malek, Marcus M Carullo, Philip C Journal Article United States J Clin Anesth. 2021 Aug;71:110254. doi: 10.1016/j.jclinane.2021.110254. Epub 2021 Mar 19. PY - 2021 SN - 0952-8180 SP - 110254 ST - The addition of clonidine to ropivacaine in rectus sheath nerve blocks for pediatric patients undergoing laparoscopic appendectomy: A double blinded randomized prospective study T2 - J Clin Anesth TI - The addition of clonidine to ropivacaine in rectus sheath nerve blocks for pediatric patients undergoing laparoscopic appendectomy: A double blinded randomized prospective study VL - 71 ID - 4137 ER - TY - JOUR AB - OBJECTIVE: To survey the prevalence, types, and characteristics of headache in junior high school students. MATERIAL AND METHOD: A two-stage study was conducted in seventh grade students in Bangkok, Thailand. A screening self-administered check-list questionnaire and a face-to-face interview followed by physical examination were performed. Headache was diagnosed and classified according to the Second Edition of the Classification of Headache Disorder criteria. RESULTS: 953 students (448 boys and 505 girls, mean-age 13.2 years) in seventh grade, participated in the present study. Eight hundred thirty three students (87.4%) reported of having five episodes of headache in the past three months. After person-to-person interview; there were 121 (12.6%), 116 (12.1%), nine (0.9%), and seven (0.7%) students who had headache attributing to rhinosinusitis/upper respiratory tract infections, migraine, nonspecific headache with upper-limit systolic blood pressure, and tension-type headache respectively. Lack of sleep and stress related to daily school-activities were reported as headache precipitator in 25 and 23 students with migraine, respectively. School absenteeism was documented in four students with migraine. Only one student received migraine prophylactic treatment. CONCLUSION: Headache was common in Thai grade seven schoolchildren. Awareness of its high prevalence in these age-group children will lead to early identification of students who may need intervention and specific treatment. AD - Department ofPediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. raavs@mahidol.ac.th AN - 20524440 AU - Visudtibhan, A. AU - Boonsopa, C. AU - Thampratankul, L. AU - Nuntnarumit, P. AU - Okaschareon, C. AU - Khongkhatithum, C. AU - Chiemchanya, S. AU - Visudhiphan, P. DA - May DP - NLM ET - 2010/06/09 IS - 5 KW - Adolescent Age Distribution Asian Continental Ancestry Group Child Cross-Sectional Studies Female Headache/classification/*epidemiology Health Surveys Humans Interviews as Topic Male Migraine Disorders/*epidemiology Prevalence Sex Distribution Students/*statistics & numerical data Surveys and Questionnaires Thailand/epidemiology LA - eng N1 - Visudtibhan, Anannit Boonsopa, Chompoonoot Thampratankul, Lunliya Nuntnarumit, Pracha Okaschareon, Chusak Khongkhatithum, Chaiyos Chiemchanya, Surang Visudhiphan, Pongsakdi Journal Article Thailand J Med Assoc Thai. 2010 May;93(5):550-7. PY - 2010 SN - 0125-2208 (Print) 0125-2208 SP - 550-7 ST - Headache in junior high school students: types & characteristics in Thai children T2 - J Med Assoc Thai TI - Headache in junior high school students: types & characteristics in Thai children VL - 93 ID - 3184 ER - TY - JOUR AB - OBJECTIVES. Many pediatric patients use complementary and alternative medicine, especially when facing a chronic illness for which treatment options are limited. So far, research on the use of complementary and alternative medicine in patients with functional gastrointestinal disease has been scarce. This study was designed to assess complementary and alternative medicine use in children with different gastrointestinal diseases, including functional disorders, to determine which factors predicted complementary and alternative medicine use and to assess the willingness of parents to participate in future studies on complementary and alternative medicine efficacy and safety. PATIENTS AND METHODS. The prevalence of complementary and alternative medicine use was assessed by using a questionnaire for 749 children visiting pediatric gastroenterology clinics of 9 hospitals in the Netherlands. The questionnaire consisted of 35 questions on the child's gastrointestinal disease, medication use, health status, past and future complementary and alternative medicine use, reasons for its use, and the necessity of complementary and alternative medicine research. RESULTS. In this study population, the frequency of complementary and alternative medicine use was 37.6%. A total of 60.3% of this group had used complementary and alternative medicine specifically for their gastrointestinal disease. This specific complementary and alternative medicine use was higher in patients with functional disorders than organic disorders (25.3% vs 17.2%). Adverse effects of allopathic medication, school absenteeism, age <= 11 years, and a low effect of conventional treatment were predictors of specific complementary and alternative medicine use. Almost all (93%) of the parents considered it important that pediatricians initiate complementary and alternative medicine research, and 51% of parents were willing to participate in future complementary and alternative medicine trials. CONCLUSIONS. Almost 40% of parents of pediatric gastroenterology patients are turning to complementary and alternative medicine for their child. Lack of effectiveness of conventional therapy, school absenteeism, and adverse effects of allopathic medication are more important predictors of complementary and alternative medicine use than the type of gastrointestinal disease. Because evidence on most complementary and alternative medicine modalities in children with gastrointestinal disorders is lacking, there is an urgent need for research in this field. AN - WOS:000258142500065 AU - Vlieger, A. M. AU - Blink, M. AU - Tromp, E. AU - Benninga, M. A. DA - Aug DO - 10.1542/peds.2008-0266 IS - 2 N1 - Vlieger, Arine M. Blink, Marjolein Tromp, Ellen Benninga, Marc A. PY - 2008 SN - 0031-4005 SP - E446-E451 ST - Use of complementary and alternative medicine by pediatric patients with functional and organic gastrointestinal diseases: Results from a multicenter survey T2 - Pediatrics TI - Use of complementary and alternative medicine by pediatric patients with functional and organic gastrointestinal diseases: Results from a multicenter survey UR - ://WOS:000258142500065 VL - 122 ID - 2640 ER - TY - JOUR AB - OBJECTIVES: We previously showed that gut-directed hypnotherapy (HT) is highly effective in the treatment of children with functional abdominal pain (FAP) and irritable bowel syndrome (IBS). Aim of this follow-up study was to investigate the long-term effects of HT vs. standard medical treatment plus supportive therapy (SMT). METHODS: All 52 participants of our previous randomized controlled trial (RCT) were invited to complete a standardized abdominal pain diary, on which pain frequency and pain intensity were scored. Furthermore, the Children's Somatization Inventory (CSI) and a general quality of life (QOL) questionnaire were filled out. Clinical remission was defined as > 80% improvement in pain scores compared with baseline. RESULTS: All 27 HT patients and 22 out of 25 SMT patients participated in this study. Two patients of the SMT group were lost to follow-up and one refused to participate. After a mean duration of 4.8 years follow-up (3.4-6.7), HT was still highly superior to conventional therapy with 68 vs. 20% of the patients in remission after treatment (P = 0.005). Pain intensity and pain frequency scores at follow-up were 2.8 and 2.3, respectively, in the HT group compared with 7.3 and 7.1 in the SMT group (P < 0.01). Also, somatization scores were lower in the HT group (15.2 vs. 22.8; P = 0.04). No differences were found in QOL, doctors' visits, and missed days of school or work between the two groups. CONCLUSIONS: The beneficial effects of gut-directed HT are long lasting in children with FAP or IBS with two thirds still in remission almost 5 years after treatment, making it a highly valuable therapeutic option. AD - Department of Pediatrics, St Antonius Hospital, Nieuwegein, The Netherlands. a.vlieger@antoniusziekenhuis.nl AN - 22310221 AU - Vlieger, A. M. AU - Rutten, J. M. AU - Govers, A. M. AU - Frankenhuis, C. AU - Benninga, M. A. DA - Apr DO - 10.1038/ajg.2011.487 DP - NLM ET - 2012/02/09 IS - 4 KW - Abdominal Pain/psychology/*therapy Adolescent Chi-Square Distribution Child Female Follow-Up Studies Humans *Hypnosis Irritable Bowel Syndrome/psychology/*therapy Male Pain Measurement Quality of Life Randomized Controlled Trials as Topic Surveys and Questionnaires Treatment Outcome LA - eng N1 - 1572-0241 Vlieger, Arine M Rutten, Juliette M T M Govers, Anita M A P Frankenhuis, Carla Benninga, Marc A Journal Article United States Am J Gastroenterol. 2012 Apr;107(4):627-31. doi: 10.1038/ajg.2011.487. Epub 2012 Feb 7. PY - 2012 SN - 0002-9270 SP - 627-31 ST - Long-term follow-up of gut-directed hypnotherapy vs. standard care in children with functional abdominal pain or irritable bowel syndrome T2 - Am J Gastroenterol TI - Long-term follow-up of gut-directed hypnotherapy vs. standard care in children with functional abdominal pain or irritable bowel syndrome VL - 107 ID - 3909 ER - TY - JOUR AB - Recurrent pains in childhood are those that occur at least three times within three months and interfere with daily activities. The most common reasons for pain are headaches and abdominal pain, and the great majority of these have no serious or treatable physical cause. Instead, a functional analysis of the antecedents and consequences of the pain for the child is needed. This requires time, trust, rapport and acceptance, as well as the development of a shared biopsychosocial understanding of the pain. Some interview questions are Suggested for this purpose. These include questions about the physical and social triggers of pain episodes, such as stress at school or at home, and modelling of pain behaviour by family members. Also included are questions about the adverse consequences of pain, Such as steep problems, difficulty in concentration, avoidance of responsibility and of feared situations, and inadvertent reinforcement of pain behaviour by solicitous behaviour on the part of parents. Among the numerous interventions for recurrent pain, those that promote learning of relaxation skills are the best established. A cognitive-behavioural, biopsychosocial approach to treating recurrent pain is well supported by research evidence. Primary care physicians and paediatric consultants can help to prevent and relieve children's recurrent pain. AN - WOS:000254512000008 AU - von Baeyer, C. L. DA - Feb DO - 10.1093/pch/12.2.121 IS - 2 N1 - von Baeyer, Carl L. von Baeyer, Carl/0000-0002-6308-1966 1918-1485 PY - 2007 SN - 1205-7088 SP - 121-125 ST - Understanding and managing children's recurrent pain in primary care: A biopsychosocial perspective T2 - Paediatrics & Child Health TI - Understanding and managing children's recurrent pain in primary care: A biopsychosocial perspective UR - ://WOS:000254512000008 VL - 12 ID - 2702 ER - TY - JOUR AB - Research criteria proposed by Apley for identification of children with recurrent abdominal pain (RAP) have been widely adopted, but many researchers have deviated from the original definition. Ambiguities in Apley's criteria and problems caused by departures from his definition are discussed in this article. Many inconsistencies in research results may have been created by the decision of some researchers to exclude children with presumed organic causes for their pain from RAP study samples. Further precision and comparability of research results may be gained by using the two-stage approach to classification that is proposed in this article. The first stage requires no medical evaluation but is based strictly on the correspondence of RAP symptoms to temporal and severity criteria. At the second stage, subgroups of RAP are specified by using results from medical assessments or detailed patterns of symptoms. It is also suggested that researchers specify the temporal features of RAP and provide measures of impairment. Like Apley's criteria, the revised approach to classification allows the comparison of community- and school-based samples with children who have undergone medical evaluation for RAP. AN - WOS:000083117600001 AU - von Baeyer, C. L. AU - Walker, L. S. DA - Oct DO - 10.1097/00004703-199910000-00001 IS - 5 N1 - von Baeyer, CL Walker, LS von Baeyer, Carl/0000-0002-6308-1966 1536-7312 PY - 1999 SN - 0196-206X SP - 307-313 ST - Children with recurrent abdominal pain: Issues in the selection and description of research participants T2 - Journal of Developmental and Behavioral Pediatrics TI - Children with recurrent abdominal pain: Issues in the selection and description of research participants UR - ://WOS:000083117600001 VL - 20 ID - 2875 ER - TY - JOUR AB - AIM: Abdominal pain symptoms and incontinence are common in childhood. The aim of this study was to analyse abdominal pain symptoms and their associations with incontinence and symptoms of anxiety and depression in young children. METHODS: We examined 1130 children during the school entry check-up (mean age 6.2 years) and 951 participated in the study. Parents completed a questionnaire contained 11 items regarding Rome-III functional gastrointestinal disorders (FGIDs) and incontinence and 14 items from the anxious/depressed scale of the Child Behavior Checklist (CBCL). RESULTS: Of the 951 children (55.6% boys) we recruited, 30.1% had experienced abdominal pain symptoms in the past two months and 14% had complained of them at least once a week. In addition, 2.6% had irritable bowel syndrome, 11.3% had childhood functional abdominal pain, 2.4% were affected by faecal incontinence, 2.1% were affected by daytime urinary incontinence, and 5.5% were affected by nocturnal enuresis. One in ten (10.6%) had symptoms of anxiety and depression, and these were significantly higher in the children with FGIDs, particularly if they were also incontinent. CONCLUSION: Nearly a third of the children (30.1%) had abdominal pain symptoms, and FGIDs were associated with significantly higher symptoms of anxiety and depression, especially if children were also incontinent. AD - Department of Child and Adolescent Psychiatry, Saarland University Hospital, Homburg, Germany. Institute for Community Health, Saarpfalz Kreis, Homburg, Germany. Department of Clinical Psychology and Psychotherapy, Saarland University, Saarbrücken, Germany. AN - 26194632 AU - von Gontard, A. AU - Moritz, A. M. AU - Thome-Granz, S. AU - Equit, M. DA - Nov DO - 10.1111/apa.13134 DP - NLM ET - 2015/07/22 IS - 11 KW - Abdominal Pain/*complications/*diagnosis/etiology/psychology Anxiety/*complications Child Child, Preschool Cross-Sectional Studies Depression/*complications Fecal Incontinence/complications Female Gastrointestinal Diseases/complications Humans Male Urinary Incontinence/complications Abdominal pain Anxiety Child behavior checklist Depression Incontinence LA - eng N1 - 1651-2227 von Gontard, Alexander Moritz, Anne-Michaela Thome-Granz, Sigrid Equit, Monika Journal Article Norway Acta Paediatr. 2015 Nov;104(11):1156-63. doi: 10.1111/apa.13134. Epub 2015 Sep 30. PY - 2015 SN - 0803-5253 SP - 1156-63 ST - Abdominal pain symptoms are associated with anxiety and depression in young children T2 - Acta Paediatr TI - Abdominal pain symptoms are associated with anxiety and depression in young children VL - 104 ID - 3951 ER - TY - JOUR AB - OBJECTIVE: This article estimates lost work days and lost work day equivalents in a population sample of migraineurs, differentiating work loss due to headache episodes that met criteria for migraine from migrainous headaches not meeting full criteria and nonmigrainous headaches. METHODS: A random digit dialing survey of 5,071 adults identified 800 subjects with migraine headaches. By clinical examination, a subsample of 225 met migraine diagnostic criteria; 174 of these patients completed at least 11 weeks of daily diaries. This report concerns the subgroup of 122 individuals with regular paid employment. Subjects completed a daily diary over a 3-month period to assess the occurrence of headaches and International Headache Society (IHS) criteria for each headache occurrence. We report estimates of lost work days and lost work day equivalents by type of headache. RESULTS: Participants reported headaches on 8.1 work days, of which 2.2 headache days met criteria for migraine (IHS 1.1, 1.2), and an additional 2.1 headache days were migrainous without meeting full migraine criteria (IHS 1.7). On average, migraineurs missed 1.1 days of work due to headache in 3 months, of which 0.7 lost work days were due to migraine and 0.3 were due to migrainous headaches. When at work with headache, work effectiveness was reduced 41% for migraine headaches, 28% for migrainous headaches, and 24% for other headaches. Over 3 months, migraineurs experienced an average of 3.0 lost work day equivalents, of which 1.4 were due to migraine and an additional 0.7 were due to migrainous headaches. The most disabled 20% of the participants accounted for 77% of the lost work days; 40% of subjects accounted for 75% of the lost work day equivalents. CONCLUSIONS: Employed migraine sufferers experienced considerable work loss and reduced work performance due to headache. The most severely affected migraineurs accounted for most of the reduced work performance. Targeting the most severely affected persons may be necessary to reduce work loss among migraineurs substantially. AD - Center for Health Studies, Group Health Cooperative of Puget Sound, Seattle, WA 98101, USA. AN - 9633720 AU - Von Korff, M. AU - Stewart, W. F. AU - Simon, D. J. AU - Lipton, R. B. DA - Jun DO - 10.1212/wnl.50.6.1741 DP - NLM ET - 1998/06/20 IS - 6 KW - Absenteeism Adolescent Aged Female Headache/epidemiology/physiopathology Humans Incidence Male Medical Records Middle Aged Migraine Disorders/epidemiology/*physiopathology Task Performance and Analysis *Work LA - eng N1 - Von Korff, M Stewart, W F Simon, D J Lipton, R B Journal Article Research Support, Non-U.S. Gov't United States Neurology. 1998 Jun;50(6):1741-5. doi: 10.1212/wnl.50.6.1741. PY - 1998 SN - 0028-3878 (Print) 0028-3878 SP - 1741-5 ST - Migraine and reduced work performance: a population-based diary study T2 - Neurology TI - Migraine and reduced work performance: a population-based diary study VL - 50 ID - 3287 ER - TY - JOUR AB - Background and aims: A targeted pain program may prevent the progression and subsequent occurrence of chronic pain in adolescents. This study tested the effectiveness of a new acceptance and commitment therapy-based pain management intervention, using physical and psychological functions as the outcomes. The objective was also to determine whether Pediatric Pain Screening Tool risk profiles function as outcome moderator in the current sample. A valid screening tool would enable the program development. Methods: Thirty-two consecutive adolescent patients (13-17 years old) with idiopathic recurrent musculoskeletal pain completed the study. The intervention comprised acceptance and commitment therapy-oriented multidisciplinary treatment. Pediatric Pain Screening Tool, pain frequency, functional disability, school attendance, physical endurance, depressive symptoms, and catastrophizing coping style were measured before treatment (baseline) and again at 6 and 12 months after the initiation of treatment. To test the effectiveness of the new program, we also determined whether the original risk classification of each patient remained constant during the intervention. Results: The intervention was effective for high-risk patients. In particular, the pain frequency decreased, and psychosocial measures improved. In post-intervention, the original risk classification of seven patients in the high-risk category changed to medium-risk. PPST classification acted as a moderator of the outcome of the current program. Conclusions: The categorization highlighted the need to modify the program content for the medium-risk patients. The categorization is a good tool to screen adolescent patients with pain. AN - WOS:000463370000008 AU - Vuorimaa, H. AU - Leppanen, L. AU - Kautiainen, H. AU - Mikkelsson, M. AU - Hietanen, M. AU - Vilen, H. AU - Pohjankoski, H. DA - Apr DO - 10.1515/sjpain-2018-0312 IS - 2 N1 - Vuorimaa, Hanna Leppanen, Leena Kautiainen, Hannu Mikkelsson, Marja Hietanen, Maiju Vilen, Hell Pohjankoski, Heini 1877-8879 PY - 2019 SN - 1877-8860 SP - 287-298 ST - Risk severity moderated effectiveness of pain treatment in adolescents T2 - Scandinavian Journal of Pain TI - Risk severity moderated effectiveness of pain treatment in adolescents UR - ://WOS:000463370000008 VL - 19 ID - 1938 ER - TY - JOUR AB - We aimed to determine the economic impact of absenteeism and presenteeism from five conditions potentially comorbid with depressive symptoms-back or neck disorders, depression, anxiety, or emotional disorders, chronic headaches, stomach or bowel disorders, and insomnia-among Japanese workers aged 18-59 yr. Participants from 19 workplaces anonymously completed Stanford Presenteeism Scale questionnaires. Participants identified one primary health condition and determined the resultant performance loss (0-100%) over the previous 4-wk period. We estimated the wage loss by gender, using 10-yr age bands. A total of 6,777 participants undertook the study. Of these, we extracted the data for those in the 18-59 yr age band who chose targeted primary health conditions (males, 2,535; females 2,465). The primary health condition identified was back or neck disorders. We found that wage loss due to presenteeism and absenteeism per 100 workers across all 10-yr age bands was high for back or neck disorders. Wage loss per person was relatively high among those identifying depression, anxiety, or emotional disorders. These findings offer insight into developing strategies for workplace interventions on increasing work performance. AD - Bureau of International Cooperation, National Center for Global Health and Medicine (NCGM), Japan. AN - 23892900 AU - Wada, K. AU - Arakida, M. AU - Watanabe, R. AU - Negishi, M. AU - Sato, J. AU - Tsutsumi, A. C2 - PMC4202740 DO - 10.2486/indhealth.2013-0016 DP - NLM ET - 2013/07/31 IS - 5 KW - *Absenteeism Adolescent Adult Age Factors Back Pain/economics/epidemiology Comorbidity Efficiency, Organizational/*economics Female Headache Disorders/economics/epidemiology Humans Intestinal Diseases/economics/epidemiology Japan/epidemiology Male Mental Disorders/*economics/*epidemiology Middle Aged Neck Pain/economics/epidemiology Salaries and Fringe Benefits/*statistics & numerical data Sex Factors Sleep Initiation and Maintenance Disorders/economics/epidemiology Stomach Diseases/economics/epidemiology Surveys and Questionnaires Young Adult LA - eng N1 - 1880-8026 Wada, Koji Arakida, Mikako Watanabe, Rika Negishi, Motomi Sato, Jun Tsutsumi, Akizumi Journal Article Research Support, Non-U.S. Gov't Ind Health. 2013;51(5):482-9. doi: 10.2486/indhealth.2013-0016. Epub 2013 Jul 26. PY - 2013 SN - 0019-8366 (Print) 0019-8366 SP - 482-9 ST - The economic impact of loss of performance due to absenteeism and presenteeism caused by depressive symptoms and comorbid health conditions among Japanese workers T2 - Ind Health TI - The economic impact of loss of performance due to absenteeism and presenteeism caused by depressive symptoms and comorbid health conditions among Japanese workers VL - 51 ID - 3478 ER - TY - JOUR AB - BACKGROUND: Pelvic pain is common in adolescent girls in day-to-day practice. Severity, Affect, Family and Environment (SAFE) is a recent interview strategy to approach these patients and their families. AIM: 1. To find the prevalence of pelvic pain in adolescent girls. 2. To find out the feasibility and acceptability of "SAFE" approach in evaluating chronic pelvic pain in adolescent girls. SETTINGS & DESIGN: 200 adolescent girls aged 13-23 years were selected at random from school and colleges nearby hospital campus. METHOD: A questionnaire method was adopted. Adolescent girls selected were divided into two groups, group I (with pain) and group II (without pain). STATISTICAL ANALYSIS: It was performed using chi-square and Fischer tests with significance of p value being taken at 0.05. RESULTS: Out of 200 adolescent girls selected for interview, prevalence of pelvic pain was found to be 37.0%. Dysmenorrhoea was also found to have significant relationship with pelvic pain. Depression and anxiety, school absences and loss of weight were found to have significant association with pain. Pelvic pain was found to be more in adolescent girls with large family size (> 4 members), single parent, both parents working, ongoing marital problems at home and was less reported when there was good parent-child communication about sex and when the teenager was well prepared for menarche by the parents and the association with the above mentioned factors was found to be significant. CONCLUSION: "SAFE" approach contributes in identifying health problems in adolescent girls with chronic pelvic pain. AD - Dept of Obstetric and Gynecology, Maulana Azad Medical College, Associated Lok Nayak Hospital, New Delhi - 110 002, India. drleena_123@yahoo.co.in AN - 15286418 AU - Wadhwa, L. AU - Sharma, J. B. AU - Arora, R. AU - Malhotra, M. AU - Sharma, S. DA - Jul DP - NLM ET - 2004/08/03 IS - 7 KW - Adolescent Adult Chronic Disease Cross-Sectional Studies Family Female Humans Pelvic Pain/*diagnosis/etiology/psychology Quality of Life Surveys and Questionnaires LA - eng N1 - Wadhwa, Leena Sharma, J B Arora, R Malhotra, M Sharma, S Journal Article India Indian J Med Sci. 2004 Jul;58(7):275-82. PY - 2004 SN - 0019-5359 (Print) 0019-5359 SP - 275-82 ST - Severity, affect, family and environment (SAFE) approach to evaluate chronic pelvic pain in adolescent girls T2 - Indian J Med Sci TI - Severity, affect, family and environment (SAFE) approach to evaluate chronic pelvic pain in adolescent girls VL - 58 ID - 3283 ER - TY - BOOK A2 - Dobe, M. A2 - Zernikow, B. AB - By definition, a pain disorder is a biopsychosocial disease. Irrespective of their individual proportion, diagnostics in pain disorders must always assess biological, psychological and social factors. Medical diagnostic procedures explore whether, for example, physical diseases have contributed to the development and maintenance of the pain disorder or whether they have a negative impact on it. Psychological diagnostics assess emotional determinants, the appearance of dysfunctional cognitions or coping strategies, and the degree of pain-related impairment of the child's life. Diagnostics of social factors investigate possible dysfunctional behaviours within the family system or elsewhere, and the interaction between the pain disorder and dysfunctional behaviours within the family, school or peer group. Additionally, it is important to identify the child's and his/her family's specific resources. This chapter describes the procedures necessary for a comprehensive assessment. AN - WOS:000550989700007 AU - Wager, J. AU - Kriszio, H. AU - Frosch, M. AU - Dobe, M. AU - Stahlschmidt, L. AU - Zernikow, B. DO - 10.1007/978-3-030-19201-3_3 N1 - Wager, Julia Kriszio, Holger Frosch, Michael Dobe, Michael Stahlschmidt, Lorin Zernikow, Boris PY - 2019 SN - 978-3-030-19201-3; 978-3-030-19200-6 SP - 35-50 ST - Diagnostics of Chronic Pain in Children and Adolescents T2 - Practical Treatment Options for Chronic Pain in Children and Adolescents: An Interdisciplinary Therapy Manual, 2nd Edition TI - Diagnostics of Chronic Pain in Children and Adolescents UR - ://WOS:000550989700007 ID - 1961 ER - TY - JOUR AB - The aim of the present thesis was to investigate different aspects of temporomandibular disorders (TMD) and pain such as prevalence, diagnostics, and treatment among adolescents. The reliability of a questionnaire and the clinical examination and diagnoses according to the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) were assessed. Overall, we found it possible to assess and diagnose TMD in adolescents in a reliable way. The prevalence of TMD pain, gender differences, and the need for treatment were investigated among 864 adolescents from a Public Dental Service clinic. Seven percent of the subjects received a pain diagnosis according to the RDC/TMD, and the prevalence was higher among girls than boys. More subjects with TMD pain reported school absence and analgesic consumption compared to controls. Approximately every second subject who reported TMD pain also perceived a need for treatment. In an evaluation of psychosocial and dental factors, the following were found to play an important role in adolescents with TMD: stress, somatic complaints, and emotional problems. Three treatment methods were compared in a randomized controlled trial: brief information only, brief information and occlusal appliance, and brief information and relaxation therapy. In the brief information and occlusal appliance group, 60%--significantly more than in the other two groups--experienced a reduction of at least 50% in TMD pain. The influence of somatic and emotional stimuli was evaluated, and we found that adolescents with TMD pain were significantly more sensitive to not only aversive somatic but also pleasant somatic stimuli compared with healthy controls. The results suggest that not only nociceptive but also cognitive processes are implicated in chronic pain states in young TMD subjects. In conclusion, TMD pain is more common in girls than in boys and affects daily life. TMD pain in adolescents can best be improved by traditional treatment with occlusal appliance combined with brief information. AD - Department of Stomatognathic Physiology, Faculty of Odontology, Malmö University, Malmö Sweden. AN - 14717039 AU - Wahlund, K. DP - NLM ET - 2004/01/14 IS - 164 KW - Adolescent Facial Pain/etiology/therapy Female Humans Male Multivariate Analysis Occlusal Splints Patient Education as Topic Prevalence Relaxation Therapy Sex Ratio Sweden/epidemiology Temporomandibular Joint Disorders/diagnosis/*epidemiology/psychology/*therapy LA - eng N1 - Wahlund, Kerstin Clinical Trial Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't Review Sweden Swed Dent J Suppl. 2003;(164):inside front cover, 2-64. PY - 2003 SN - 0348-6672 (Print) 0348-6672 SP - inside front cover, 2-64 ST - Temporomandibular disorders in adolescents. Epidemiological and methodological studies and a randomized controlled trial T2 - Swed Dent J Suppl TI - Temporomandibular disorders in adolescents. Epidemiological and methodological studies and a randomized controlled trial ID - 4019 ER - TY - JOUR AB - AIMS: To compare the effects of occlusal appliance therapy (OA) and therapist-guided relaxation training (RT) on temporomandibular disorder (TMD) pain in adolescents, thereby replicating a previous randomized controlled trial, and to explore whether additional therapy administered in a crossover sequential design improves treatment outcomes. METHODS: The study involved 64 adolescents, aged 12 to 19 years, experiencing TMD pain at least once a week and diagnosed with myofascial pain in accordance with the Research Diagnostic Criteria for TMD. For phase 1 of the study, subjects were randomly assigned to OA or RT; nonresponders were offered the other treatment in phase 2. Self-reports of TMD pain and clinical assessments were performed before and after treatment in each phase and 6 months after the last treatment phase. Differences in outcomes between treatment groups across the different phases were analyzed by analysis of covariance (ANCOVA), and for differences in proportions, the chi-square test was used. RESULTS: After phase 1, a significantly higher proportion of adolescents treated with OA (62.1%) than those treated with RT (17.9%) responded to treatment, defined as a subjective report of "Completely well/Very much improved" or "Much improved." Similar differences in self- report of treatment effect occurred after phase 2. About two-thirds of all adolescents in both phases reported such an improvement level at the 6-month follow-up, including a somewhat higher proportion of phase 1 responders (79.2%) than phase 1 nonresponders (60%). CONCLUSION: The findings suggest that, for adolescents with TMD pain, use of standardized clinical treatment with OA is more effective than RT on self-evaluation of treatment improvement. For nonresponders, subsequent crossover treatment might be useful to improve subjective TMD pain. AN - 25635959 AU - Wahlund, K. AU - Nilsson, I. M. AU - Larsson, B. DA - Winter DO - 10.11607/ofph.1285 DP - NLM ET - 2015/01/31 IS - 1 KW - Absenteeism Adolescent Analgesics/therapeutic use Attitude to Health Breathing Exercises Child Cross-Over Studies Female Follow-Up Studies Humans Male Medical Records Motivation Muscle Contraction/physiology *Occlusal Splints Pain Measurement Patient Compliance Patient Satisfaction Range of Motion, Articular/physiology Relaxation Relaxation Therapy/*methods Self Report Temporomandibular Joint Dysfunction Syndrome/*therapy Treatment Outcome Young Adult LA - eng N1 - Wahlund, Kerstin Nilsson, Ing-Marie Larsson, Bo Comparative Study Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't United States J Oral Facial Pain Headache. 2015 Winter;29(1):41-50. doi: 10.11607/ofph.1285. PY - 2015 SN - 2333-0384 (Print) SP - 41-50 ST - Treating temporomandibular disorders in adolescents: a randomized, controlled, sequential comparison of relaxation training and occlusal appliance therapy T2 - J Oral Facial Pain Headache TI - Treating temporomandibular disorders in adolescents: a randomized, controlled, sequential comparison of relaxation training and occlusal appliance therapy VL - 29 ID - 3333 ER - TY - JOUR AB - INTRODUCTION: Chronic pain in adolescents is a significant medical condition, affecting the physical and psychological well-being of youth and their families. Pain-related stigma is a significant psychosocial factor in adolescents with chronic pain that has been understudied, despite its implications for negative health outcomes, poor quality of life, and increased healthcare utilization. OBJECTIVES: To examine pain-related stigma in the literature documenting pediatric and adult health-related stigma and present preliminary findings from a focus group of adolescents with chronic pain. METHODS: In this narrative review, we explored pain-related stigma research and conceptualized the literature to address pain-related stigma among adolescents with chronic pain. Additionally, we conducted a focus group of four adolescent females with chronic pain and using content analyses, coded the data for preliminary themes. RESULTS: We propose a pain-related stigma model and framework based on our review and the findings from our focus group. Findings suggest that medical providers, school personnel (ie, teachers and school nurses), peers and even family members enact pain-related stigma toward adolescents with chronic pain. CONCLUSIONS: Based on this narrative review, there is preliminary evidence of pain-related stigma among adolescents with chronic pain and future research is warranted to better understand the nature and extent of this stigma within this population. AD - Division of Pain and Palliative Medicine, Connecticut Children's Medical Center, University of Connecticut School of Medicine, Hartford, CT, USA. Department of Human Development and Family Studies, Rudd Center for Food Policy and Obesity, University of Connecticut, Hartford, CT, USA. Division of Behavioral Sciences and Community Health, University of Connecticut Health Center, Hartford, CT, USA. AN - 30324171 AU - Wakefield, E. O. AU - Zempsky, W. T. AU - Puhl, R. M. AU - Litt, M. D. C2 - PMC6172824 DA - Sep DO - 10.1097/pr9.0000000000000679 DP - NLM ET - 2018/10/17 IS - Suppl 1 KW - Adolescents Chronic pain Stigma the end of this article. LA - eng N1 - 2471-2531 Wakefield, Emily O Zempsky, William T Puhl, Rebecca M Litt, Mark D Journal Article Pain Rep. 2018 Sep 11;3(Suppl 1):e679. doi: 10.1097/PR9.0000000000000679. eCollection 2018 Sep. PY - 2018 SN - 2471-2531 SP - e679 ST - Conceptualizing pain-related stigma in adolescent chronic pain: a literature review and preliminary focus group findings T2 - Pain Rep TI - Conceptualizing pain-related stigma in adolescent chronic pain: a literature review and preliminary focus group findings VL - 3 ID - 4047 ER - TY - JOUR AB - The association between tension-type headache and cognitive ability was assessed among 971 members of a longitudinal birth cohort study. Primary headache status was determined at age 32 years according to 2004 International Headache Society criteria, frequent childhood headaches were identified from parent report from ages 7 to 13 years, and data relating to cognitive and academic performance from ages 3 to 32 years were analyzed. Adult study members with tension-type headache did not score worse on any of the cognitive measures relative to headache-free controls or headache-free tinnitus sufferers. Instead, a consistent relation was found between childhood headache (regardless of headache diagnosis in adulthood) and lower scores on most cognitive measures from age 3 years through adolescence (verbal and performance IQ, receptive language, and reading scores). The data indicate that cognitive performance deficits in childhood headache sufferers can probably be attributed to factors stemming from utero or early childhood. AD - Department of Psychology, University of Auckland, Private Bag 92101, Auckland, 1042, New Zealand. k.waldie@auckland.ac.nz AN - 18173981 AU - Waldie, K. E. AU - Welch, D. DA - Dec DO - 10.1007/s11916-007-0233-1 DP - NLM ET - 2008/01/05 IS - 6 KW - Adolescent Adult Analysis of Variance Child Child, Preschool Cognition/*physiology Cognition Disorders/*etiology/*psychology Data Interpretation, Statistical Educational Status Female Humans Intelligence Tests Longitudinal Studies Male New Zealand/epidemiology Reading Sex Factors Socioeconomic Factors Tension-Type Headache/*complications/epidemiology/*psychology Tinnitus/psychology Verbal Behavior/physiology LA - eng N1 - Waldie, Karen E Welch, David MH45070/MH/NIMH NIH HHS/United States Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't United States Curr Pain Headache Rep. 2007 Dec;11(6):454-60. doi: 10.1007/s11916-007-0233-1. PY - 2007 SN - 1531-3433 (Print) 1534-3081 SP - 454-60 ST - Cognitive function in tension-type headache T2 - Curr Pain Headache Rep TI - Cognitive function in tension-type headache VL - 11 ID - 3518 ER - TY - JOUR AB - Background There is increasing evidence for the use of bisphosphonates to treat Complex Regional Pain Syndrome in adults. However, there are scarce data for their use in children with Complex Regional Pain Syndrome. Aim This retrospective case series aimed to analyze the effects of intravenous bisphosphonate use in children and adolescents with Complex Regional Pain Syndrome enrolled in a multidimensional pain treatment program. Methods We analyzed the data of 16 patients (15 females and 1 male, mean age 14 +/- 3 years) who received infusions of zoledronic acid (0.015 +/- 0.0044mg/kg), pamidronate (0.72 +/- 0.17mg/kg), or both depending on their initial response between October 2014 and December 2019. The primary endpoint of the study was the patient's global impression of change. Secondary outcomes included pain intensity, physical function, role function (school attendance), need for pain medications, and adverse effects. Results Nine of 16 patients reported meaningful improvements (global impressions of change of 84% or higher) at a median follow-up time of 16 (8-21) months after their last infusion of bisphosphonates. There were also meaningful reductions in pain intensity and the need for pain medications. There was an increase in the proportion of patients with minimal or without physical disability, and almost all patients normalized their school activities. Thirteen patients (81%) reported adverse effects, mostly flu-like symptoms, for a few days after the infusion. Conclusion The use of bisphosphonate infusions may represent an effective treatment option for children with Complex Regional Pain Syndrome, not responding to multidisciplinary pain treatment programs. AN - WOS:000657392700001 AU - Walfish, L. AU - Sbrocchi, A. M. AU - Rivera, G. AU - Gracia, L. E. R. AU - Mohamed, N. AU - Cardenas, V. H. G. AU - Stoopler, M. AU - Ingelmo, P. DO - 10.1111/pan.14207 N1 - Walfish, Laurel Sbrocchi, Anne Marie Rivera, Gonzalo Ricaurte Gracia, Laura E. Mohamed, Nada Gonzalez Cardenas, Victor Hugo Stoopler, Michelle Ingelmo, Pablo 1460-9592 SN - 1155-5645 ST - Use of bisphosphonates in a retrospective case series of children and adolescents with complex regional pain syndrome T2 - Pediatric Anesthesia TI - Use of bisphosphonates in a retrospective case series of children and adolescents with complex regional pain syndrome UR - ://WOS:000657392700001 ID - 1735 ER - TY - JOUR AB - BACKGROUND: There is increasing evidence for the use of bisphosphonates to treat Complex Regional Pain Syndrome in adults. However, there are scarce data for their use in children with Complex Regional Pain Syndrome. AIM: This retrospective case series aimed to analyze the effects of intravenous bisphosphonate use in children and adolescents with Complex Regional Pain Syndrome enrolled in a multidimensional pain treatment program. METHODS: We analyzed the data of 16 patients (15 females and 1 male, mean age 14 ± 3 years) who received infusions of zoledronic acid (0.015 ± 0.0044mg/kg), pamidronate (0.72 ± 0.17mg/kg), or both depending on their initial response between October 2014 and December 2019. The primary endpoint of the study was the patient's global impression of change. Secondary outcomes included pain intensity, physical function, role function (school attendance), need for pain medications, and adverse effects. RESULTS: Nine of 16 patients reported meaningful improvements (global impressions of change of 84% or higher) at a median follow-up time of 16 (8-21) months after their last infusion of bisphosphonates. There were also meaningful reductions in pain intensity and the need for pain medications. There was an increase in the proportion of patients with minimal or without physical disability, and almost all patients normalized their school activities. Thirteen patients (81%) reported adverse effects, mostly flu-like symptoms, for a few days after the infusion. CONCLUSION: The use of bisphosphonate infusions may represent an effective treatment option for children with Complex Regional Pain Syndrome, not responding to multidisciplinary pain treatment programs. AD - Faculty of Medicine, McGill University, Montreal, QC, Canada. Department of Endocrinology, Montreal Children's Hospital, McGill University Health Center, Montreal, QC, Canada. Chronic Pain Unit, Department of Anesthesia, Clínica Las Condes, Santiago, Chile. School of Medicine, Fundación Universitaria de Ciencias de la Salud (FUCS), Bogotá, Colombia. Department of Pediatric Anesthesia, Edwards Family Interdisciplinary Centre for Chronic Pain, Montreal Children's Hospital, McGill University Health Center, Montreal, QC, Canada. Department of Anesthesia, Department of Anesthesia, Pain & Palliative Care, Los Cobos Medical Center, Hospital Universitario de la Samaritana, Bogotá, Colombia. The Alan Edward Centre for Research on Pain, McGill University, Montreal, QC, Canada. AN - 33999470 AU - Walfish, L. AU - Sbrocchi, A. M. AU - Rivera, G. AU - Ricaurte Gracia, L. E. AU - Mohamed, N. AU - González Cárdenas, V. H. AU - Stoopler, M. AU - Ingelmo, P. DA - May 17 DO - 10.1111/pan.14207 DP - NLM ET - 2021/05/18 KW - adolescent bisphosphonates child chronic pain complex regional pain syndromes LA - eng N1 - 1460-9592 Walfish, Laurel Sbrocchi, Anne Marie Rivera, Gonzalo Ricaurte Gracia, Laura E Mohamed, Nada González Cárdenas, Víctor Hugo Stoopler, Michelle Orcid: 0000-0002-9296-5103 Ingelmo, Pablo Orcid: 0000-0001-6888-0102 Montreal Children's Hospital Foundation/ Journal Article France Paediatr Anaesth. 2021 May 17. doi: 10.1111/pan.14207. PY - 2021 SN - 1155-5645 ST - Use of bisphosphonates in a retrospective case series of children and adolescents with complex regional pain syndrome T2 - Paediatr Anaesth TI - Use of bisphosphonates in a retrospective case series of children and adolescents with complex regional pain syndrome ID - 4155 ER - TY - JOUR AB - Prior investigations of the relation between stressors and symptoms in children with recurrent abdominal pain (RAP) have focused on major negative life events. This study used consecutive daily telephone interviews to assess daily stressors and symptoms in 154 pediatric patients with RAP and 109 well children. Results showed that patients with RAP reported more frequent daily stressors than well children reported both at home and at school. Idiographic (within-subject) analyses indicated that the association between daily stressors and somatic symptoms was significantly stronger for patients with RAP than for well children. In contrast, the relation between daily stressors and negative affect did not differ between the groups. The relation between daily stressors and somatic symptoms was stronger for patients with RAP who had higher levels of trait negative affectivity. AN - WOS:000170876300010 AU - Walker, L. S. AU - Garber, J. AU - Smith, C. A. AU - Van Slyke, D. A. AU - Claar, R. L. DA - Feb DO - 10.1037//0022-006x.69.1.85 IS - 1 N1 - Walker, LS Garber, J Smith, CA Van Slyke, DA Claar, RL Smith, Craig A./AAE-2844-2020 Smith, Craig A./0000-0001-6624-2684 PY - 2001 SN - 0022-006X SP - 85-91 ST - The relation of daily stressors to somatic and emotional symptoms in children with and without recurrent abdominal pain T2 - Journal of Consulting and Clinical Psychology TI - The relation of daily stressors to somatic and emotional symptoms in children with and without recurrent abdominal pain UR - ://WOS:000170876300010 VL - 69 ID - 2855 ER - TY - JOUR AB - Assessed attributions and responses to descriptions of the misbehavior of children with symptoms of physical and emotional illnesses. Subjects (160 mothers; 160 fathers) read a vignette about a child in one of four illness conditions (medically explained pain with organic etiology; medically unexplained pain, depression, well) who was described as misbehaving at home and school. Within each illness condition, the child protagonist varied by age (8 vs. 16) and gender. A between-subjects design was used in which subjects made judgments regarding causes and responsibility for the child's misbehavior, affective reactions to the child, and the consequences that should be administered to the child. Results indicated that, in comparison to subjects' perceptions of the misbehavior of children in the other conditions, subjects viewed the misbehavior of children with medically explained pain as less intentional, more excusable, and due to causes that were less internal to the child. Subjects held children with medically explained pain less responsible for their misbehavior and indicated that they would respond to them with less anger, disappointment, blame, and punishment than to children in the other conditions. Subjects did not hold children with symptoms of depression and children with unexplained pain complaints less responsible for their misbehavior, but indicated that they would respond to them with less anger, disappointment, and punishment than to well children. AD - Division of Adolescent Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA. AN - 7595820 AU - Walker, L. S. AU - Garber, J. AU - Van Slyke, D. A. DA - Jun DO - 10.1093/jpepsy/20.3.329 DP - NLM ET - 1995/06/01 IS - 3 KW - Adolescent Adult Analysis of Variance Causality Child *Child Behavior Depressive Disorder/psychology Female Humans Internal-External Control Male Pain/psychology *Parent-Child Relations *Sick Role United States LA - eng N1 - Walker, L S Garber, J Van Slyke, D A HD23264/HD/NICHD NIH HHS/United States R29-MH4545801A1/MH/NIMH NIH HHS/United States Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. United States J Pediatr Psychol. 1995 Jun;20(3):329-45. doi: 10.1093/jpepsy/20.3.329. PY - 1995 SN - 0146-8693 (Print) 0146-8693 SP - 329-45 ST - Do parents excuse the misbehavior of children with physical or emotional symptoms? An investigation of the pediatric sick role T2 - J Pediatr Psychol TI - Do parents excuse the misbehavior of children with physical or emotional symptoms? An investigation of the pediatric sick role VL - 20 ID - 3894 ER - TY - JOUR AB - Investigated somatic and emotional symptoms, functional disability, and health service utilization in 31 former RAP patients and 31 former well patients who had originally been interviewed 5 to 6 years earlier. Both former patients and their mothers were interviewed for this follow-up study. Medical records were obtained for those patients who reported receiving new diagnoses for abdominal pain since their initial assessment. Results indicated that only one of the former RAP patients was later diagnosed with organic disease that clearly accounted for his earlier abdominal pain. Nonetheless, at follow-up former RAP patients reported significantly higher levels of abdominal pain, other somatic symptoms, and functional disability (including school/work absence) than did former well patients. Mothers reported higher levels of internalizing emotional symptoms in former RAP patients than in former well patients. AD - Division of Adolescent Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-3571, USA. AN - 7760222 AU - Walker, L. S. AU - Garber, J. AU - Van Slyke, D. A. AU - Greene, J. W. DA - Apr DO - 10.1093/jpepsy/20.2.233 DP - NLM ET - 1995/04/01 IS - 2 KW - Abdominal Pain/diagnosis/*psychology Adaptation, Psychological Adolescent Adult Female Health Services/statistics & numerical data Humans *Long-Term Care Male Recurrence Severity of Illness Index Somatoform Disorders/diagnosis/psychology LA - eng N1 - Walker, L S Garber, J Van Slyke, D A Greene, J W HD23264/HD/NICHD NIH HHS/United States Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. United States J Pediatr Psychol. 1995 Apr;20(2):233-45. doi: 10.1093/jpepsy/20.2.233. PY - 1995 SN - 0146-8693 (Print) 0146-8693 SP - 233-45 ST - Long-term health outcomes in patients with recurrent abdominal pain T2 - J Pediatr Psychol TI - Long-term health outcomes in patients with recurrent abdominal pain VL - 20 ID - 3383 ER - TY - JOUR AB - Assessed attributions and responses to descriptions of the misbehavior of children with symptoms of physical and emotional illnesses. Subjects (160 mothers; 160 fathers) read a vignette about a child in one of four illness conditions (medically explained pain with organic etiology; medically unexplained pain, depression, well) who was described as misbehaving at home and school. Within each illness condition, the child protagonist varied by age (8 vs. 16) and gender. A between-subjects design was used in which subjects made judgments regarding causes and responsibility for the child's misbehavior, affective reactions to the child, and the consequences that should be administered to the child. Results indicated that, in comparison to subjects' perceptions of the misbehavior of children in the other conditions, subjects viewed the misbehavior of children with medically explained pain as less intentional, more excusable, and due to causes that were less internal to the child. Subjects held children with medically explained pain less responsible for their misbehavior and indicated that they would respond to them with less anger, disappointment, blame, and punishment than to children in the other conditions. Subjects did not hold children with symptoms of depression and children with unexplained pain complaints less responsible for their misbehavior, but indicated that they would respond to them with less anger, disappointment, and punishment than to well children. AN - WOS:A1995QY99500006 AU - Walker, L. S. AU - Garber, J. AU - Vanslyke, D. A. DA - Jun DO - 10.1093/jpepsy/20.3.329 IS - 3 N1 - Walker, ls garber, j vanslyke, da PY - 1995 SN - 0146-8693 SP - 329-345 ST - DO PARENTS EXCUSE THE MISBEHAVIOR OF CHILDREN WITH PHYSICAL OR EMOTIONAL SYMPTOMS - AN INVESTIGATION OF THE PEDIATRIC SICK ROLE T2 - Journal of Pediatric Psychology TI - DO PARENTS EXCUSE THE MISBEHAVIOR OF CHILDREN WITH PHYSICAL OR EMOTIONAL SYMPTOMS - AN INVESTIGATION OF THE PEDIATRIC SICK ROLE UR - ://WOS:A1995QY99500006 VL - 20 ID - 2936 ER - TY - JOUR AB - Investigated somatic and emotional symptoms, functional disability and health service utilization in 31 former RAP patients and 32 former well patients who had originally been interviewed 5 to 6 years earlier. Both former patients and their mothers were interviewed for this follow-up study. Medical records were obtained for those patients who reported receiving new diagnoses for abdominal pain since their initial assessment. Results indicated that only one of the former RAP patients was later diagnosed with organic disease that clearly accounted for his earlier abdominal pain. Nonetheless, at follow-lip former RAP patients reported significantly higher levels of abdominal pain, other somatic symptoms, and functional disability (including school/work absence) than did former well patients. Mothers reported higher levels of internalizing emotional symptoms in former RAP patients than in former well patients. AN - WOS:A1995QV80100007 AU - Walker, L. S. AU - Garber, J. AU - Vanslyke, D. A. AU - Greene, J. W. DA - Apr DO - 10.1093/jpepsy/20.2.233 IS - 2 N1 - Walker, ls garber, j vanslyke, da greene, jw PY - 1995 SN - 0146-8693 SP - 233-245 ST - LONG-TERM HEALTH OUTCOMES IN PATIENTS WITH RECURRENT ABDOMINAL-PAIN T2 - Journal of Pediatric Psychology TI - LONG-TERM HEALTH OUTCOMES IN PATIENTS WITH RECURRENT ABDOMINAL-PAIN UR - ://WOS:A1995QV80100007 VL - 20 ID - 2939 ER - TY - JOUR AB - Objectives: To assess symptoms of irritable bowel syndrome (IBS) in patients with recurrent abdominal pain (RAP) 5 years after their initial evaluation, to identify the relation of IBS symptoms to functional disability and health service use, and to determine the extent to which IBS symptoms are associated with life stress and poor psychosocial adjustment. Methods: Patients with RAP (n = 76) and control subjects (n = 49) completed a telephone interview; measures included the Bowel Disease Questionnaire, the Functional Disability Inventory, the Life Events Questionnaire, the Family Inventory of Life Events, the Center for Epidemiological Studies Depression Scale, the Self-Perception Profile for Adolescents, and the Health Resources Inventory. Results: Five years after the initial evaluation, patients with RAP reported significantly more episodes of abdominal pain than did control subjects, as well as significantly higher levels of functional disability school absence, and clinic visits for abdominal distress. Female patients with RAP were more likely than female control subjects to meet the Manning criteria for IBS. Among patients with RAP, higher levels of IBS symptoms were associated with significantly greater functional disability, more clinic visits, more life stress, higher levels of depression, and lower academic and social competence. Conclusion: Female patients with a history of RAP may be at increased risk of IBS during adolescence and young adulthood. Among adolescents and young adults with a history of RAP, IBS symptoms are likely to be associated with high levels of disability and health service use. AN - WOS:000074065100020 AU - Walker, L. S. AU - Guite, J. W. AU - Duke, M. AU - Barnard, J. A. AU - Greene, J. W. DA - Jun DO - 10.1016/s0022-3476(98)70400-7 IS - 6 N1 - Walker, LS Guite, JW Duke, M Barnard, JA Greene, JW Guite, Jessica/AAP-9947-2021 Guite, Jessica/0000-0003-1038-3386 1097-6833 PY - 1998 SN - 0022-3476 SP - 1010-1015 ST - Recurrent abdominal pain: A potential precursor of irritable bowel syndrome in adolescents and young adults T2 - Journal of Pediatrics TI - Recurrent abdominal pain: A potential precursor of irritable bowel syndrome in adolescents and young adults UR - ://WOS:000074065100020 VL - 132 ID - 2896 ER - TY - JOUR AB - Significant advances in the assessment and management of acute pain in children have been made, and are supported by an increase in the availability and accessibility of evidence-based data. However, methodological and practical issues in the design and performance of clinical paediatric trials limit the quantity, and may influence the quality, of current data, which lags behind that available for adult practice. Collaborations within research networks, which incorporate both preclinical and clinical studies, may increase the feasibility and specificity of future trials. In early life, the developing nervous system responds differently to pain, analgesia, and injury, resulting in effects not seen in later life and which may have long-term consequences. Translational laboratory studies further our understanding of developmental changes in nociceptor pathway structure and function, analgesic pharmacodynamics, and the impact of different forms of injury. Chronic pain in children has a negative impact on quality of life, resulting in social and emotional consequences for both the child and the family. Despite age-related differences in many chronic pain conditions, such as neuropathic pain, management in children is often empirically based on data from studies in adults. There is a major need for further clinical research, training of health-care providers, and increased resources, to improve management and outcomes for children with chronic pain. AN - WOS:000256757700015 AU - Walker, S. M. DA - Jul DO - 10.1093/bja/aen097 IS - 1 N1 - Walker, S. M. Annual Meeting of the Royal-College-of-Anaesthetists Apr, 2007 Fac Pain Med, London, ENGLAND Royal Coll Anaesthet Walker, Suellen M/I-6080-2012 Walker, Suellen/0000-0002-6086-9459 1471-6771 PY - 2008 SN - 0007-0912 SP - 101-110 ST - Pain in children: recent advances and ongoing challenges T2 - British Journal of Anaesthesia TI - Pain in children: recent advances and ongoing challenges UR - ://WOS:000256757700015 VL - 101 ID - 2641 ER - TY - JOUR AB - Nociceptive pathways are functional following birth. In addition to physiological and behavioral responses, neurophysiological measures and neuroimaging evaluate nociceptive pathway function and quantify responses to noxious stimuli in preterm and term neonates. Intensive care and surgery can expose neonates to painful stimuli when the developing nervous system is sensitive to changing input, resulting in persistent impacts into later childhood. Early pain experience has been correlated with increased sensitivity to subsequent painful stimuli, impaired neurodevelopmental outcomes, and structural changes in brain development. Parallel preclinical studies have elucidated underlying mechanisms and evaluate preventive strategies to inform future clinical trials. AN - WOS:000324898200012 AU - Walker, S. M. DA - Sep DO - 10.1016/j.clp.2013.05.002 IS - 3 N1 - Walker, Suellen M. Walker, Suellen M/I-6080-2012 Walker, Suellen/0000-0002-6086-9459 1557-9840 PY - 2013 SN - 0095-5108 SP - 471-+ ST - Biological and Neurodevelopmental Implications of Neonatal Pain T2 - Clinics in Perinatology TI - Biological and Neurodevelopmental Implications of Neonatal Pain UR - ://WOS:000324898200012 VL - 40 ID - 2351 ER - TY - JOUR AB - Pain experienced during neonatal intensive care management can influence neurodevelopmental outcome and the somatosensory and/or emotional components of pain response in later life. Alterations in biological factors (e.g. peripheral and central somatosensory function and modulation, brain structure and connectivity) and psychosocial factors (e.g. gender, coping style, mood, parental response) that influence pain have been identified in children and young adults born very preterm or extremely preterm. Earlier gestational age at birth and cumulative pain exposure from tissue-breaking procedures and/or neonatal surgery influence the degree of change. In neonatal rodents, repeated needle insertion or hindpaw incision identify developmentally-regulated and activity-dependent long term alterations in nociceptive processing, and the efficacy of novel or current analgesic interventions can be compared. As prior neonatal experience and sex may influence current pain experience or the risk of persistent pain, these factors should be considered within the biopsychosocial assessment and formulation of pain in later life. AN - WOS:000485212200010 AU - Walker, S. M. C7 - 101005 DA - Aug DO - 10.1016/j.siny.2019.04.005 IS - 4 N1 - Walker, Suellen M. Walker, Suellen/0000-0002-6086-9459 1878-0946 PY - 2019 SN - 1744-165X ST - Long-term effects of neonatal pain T2 - Seminars in Fetal & Neonatal Medicine TI - Long-term effects of neonatal pain UR - ://WOS:000485212200010 VL - 24 ID - 1891 ER - TY - JOUR AB - Research provides ample evidence that children with chronic and debilitating medical illnesses are at increased risk for psychological and psychosocial maladjustment. Functional impairment is believed to contribute to psychosocial distress in pediatric populations, yet little is known about the specific factors that predict increased risk. Results from the total sample (N = 73) supported a conceptual model specifying that restriction of normal activities (e.g., playing with friends, attending school) would mediate the association between chronic pain and symptoms of depression. However, this process differed somewhat in preadolescent and adolescent patients. That is, among younger children (5-12 years of age), pain predicted activity restriction, which, in turn, predicted depressed affect, and activity restriction mediated the association between pain and depressed affect. In contrast, among older children (ages 13-18), activity restriction did not serve an analogous mediating role because pain was not associated with symptoms of depression in this group. Instead, pain exerted direct effects on activity restriction, and activity restriction exerted direct effects on depressed affect. AN - WOS:000078731400003 AU - Walters, A. S. AU - Williamson, G. M. DA - Win DO - 10.1207/s15326888chc2801_3 IS - 1 N1 - Walters, AS Williamson, GM PY - 1999 SN - 0273-9615 SP - 33-50 ST - The role of activity restriction in the association between pain and depression: A study of pediatric patients with chronic pain T2 - Childrens Health Care TI - The role of activity restriction in the association between pain and depression: A study of pediatric patients with chronic pain UR - ://WOS:000078731400003 VL - 28 ID - 2873 ER - TY - JOUR AB - Migraine in pediatric is a common neurological disease, and its prevalence is varying widely. The medication for the acute attack of pediatric migraine is various. we take advantage of network meta-analysis to address the efficacy and rank of these medications. Database including Pubmed and Cochrane Library were queried using a specific searching strategy. The quality of trials enrolled was assessed according to the Cochrane collaboration'tool for assessing risk of bias. The data analysis was conducted by using the core software for Cochrane reviews (Rev Man 5.3) and the Aggregate Data Drug Information System (Addis v1.16.8). The outcomes were pain-free and pain relief at 2 hours post-dose. Totally, twenty trials with high quality including 6029 migraineurs with 6912 attacks randomly assigned to 14 different drugs. The data of ketorolac and prochlorperazine were missing. We found that sumatriptan nasal spray and zolmitriptan nasal spray were superior to placebo in the two efficacy outcomes, whereas almotriptan, rizatriptan, sumatriptan with naproxen sodium, ibuprofen and ibuprofen suspension were superior to placebo only in one of the efficacy outcomes. And in network meta-analysis, we found the best 3 treatments were ibuprofen, sumatriptan with naproxen sodium and ibuprofen suspension in achieving pain-free. Meanwhile, the best 3 treatments were ibuprofen suspension, ibuprofen, and rizatriptan in achieving pain relief. In conclusion, in acute treatments of pediatric migraine, most triptans and NSAIDS were effective to achieve pain-free or pain-relief. And the most effective treatment to achieve pain-free is sumatriptan with naproxen sodium. Ibuprofen and ibuprofen suspension were the most effective treatments to achieve painrelief. AN - WOS:000601362100019 AU - Wang, G. H. AU - Tan, T. L. AU - Liu, Y. AU - Hong, P. W. C7 - 105853 DA - Aug DO - 10.1016/j.clineuro.2020.105853 N1 - Wang, Guihua Tan, Tianlin Liu, Yao Hong, Peiwei 1872-6968 PY - 2020 SN - 0303-8467 ST - Drugs for Acute Attack of Pediatric Migraine: A Network Meta-analysis of Randomized Controlled Trials T2 - Clinical Neurology and Neurosurgery TI - Drugs for Acute Attack of Pediatric Migraine: A Network Meta-analysis of Randomized Controlled Trials UR - ://WOS:000601362100019 VL - 195 ID - 1804 ER - TY - JOUR AB - BACKGROUND: Awareness is growing among clinicians of the importance of suicidal ideation in adolescents. OBJECTIVES: To investigate the relationship between migraine and suicidal ideation in a nonreferred sample of adolescents. METHODS: This study surveyed migraine and depression in three middle schools in Taitung County, Taiwan. All students completed the questionnaires, including demographics, a validated headache questionnaire, the Adolescent Depression Inventory (ADI), and the Pediatric Migraine Disability Assessment (PedMIDAS) questionnaire. This study used the presence or absence of suicidal ideation as indicated by the ADI for the analysis. RESULTS: A total of 3,963 (2,040 male and 1,923 female; mean age 14.0 +/- 0.9 years) adolescents (93% of the target cohort) completed this study. Suicidal ideation was reported in 8.5% of the study group. Compared with nonmigraine subjects (6.2%), subjects with migraine displayed a higher frequency of suicidal ideation (16.1%; odds ratio [OR] = 2.9, 95% confidence interval [CI] 2.3-3.6; p < 0.001), especially those with migraine with aura (23.9%; OR = 4.6 [95% CI 3.0-7.0]; p < 0.001). Suicidal ideation was associated with higher headache frequency and headache-related disability as measured by the PedMIDAS. After controlling for depression score and sociodemographic characteristics, the association remained only for migraine with aura (adjusted OR = 1.79 [95% CI 1.07-2.99]; p = 0.025) and high headache frequency (>7 days/month; adjusted OR = 1.69 [95% CI 1.12-2.56]; p = 0.013) but not for migraine without aura or probable migraine or PedMIDAS score. CONCLUSIONS: This study identified a higher frequency of suicidal ideation in younger adolescents with migraine with aura or high headache frequency. These associations were independent of depressive symptoms. ADI = Adolescent Depression Inventory; AOR = adjusted odds ratio; CI = confidence interval; 5-HT = serotonin; ICHD-2 = International Classification of Headache Disorders, Second Edition; MINI-Kid = Mini-International Neuropsychiatric Interview-Kid; OR = odds ratio; PedMIDAS = Pediatric Migraine Disability Assessment. AD - The Neurological Institute, Taipei Veterans General Hospital, Taipei, 112, Taiwan. sjwang@vghtpe.gov.tw AN - 19332691 AU - Wang, S. J. AU - Fuh, J. L. AU - Juang, K. D. AU - Lu, S. R. DA - Mar 31 DO - 10.1212/01.wnl.0000345362.91734.b3 DP - NLM ET - 2009/04/01 IS - 13 KW - Adolescent Age Factors Cross-Sectional Studies Data Collection/methods Depressive Disorder/complications/*epidemiology/*psychology Female Humans Male Migraine Disorders/complications/*epidemiology/*psychology Prospective Studies Risk Factors Suicide/*psychology LA - eng N1 - 1526-632x Wang, Shuu-Jiun Fuh, Jong-Ling Juang, Kai-Dih Lu, Shiang-Ru Comparative Study Journal Article Research Support, Non-U.S. Gov't United States Neurology. 2009 Mar 31;72(13):1146-52. doi: 10.1212/01.wnl.0000345362.91734.b3. PY - 2009 SN - 0028-3878 SP - 1146-52 ST - Migraine and suicidal ideation in adolescents aged 13 to 15 years T2 - Neurology TI - Migraine and suicidal ideation in adolescents aged 13 to 15 years VL - 72 ID - 3636 ER - TY - JOUR AN - 12439031 AU - Wang, W. C. DA - Nov DO - 10.1097/00043426-200211000-00003 DP - NLM ET - 2002/11/20 IS - 8 KW - Absenteeism Adolescent Adult Analgesia Anemia, Sickle Cell/*complications/therapy Biomarkers Child Home Nursing Humans Hydroxyurea/therapeutic use *Medical Records Pain/*epidemiology/etiology Pain Management Quality of Life Reproducibility of Results LA - eng N1 - Wang, Winfred C Comment Editorial United States J Pediatr Hematol Oncol. 2002 Nov;24(8):610-2. doi: 10.1097/00043426-200211000-00003. PY - 2002 SN - 1077-4114 (Print) 1077-4114 SP - 610-2 ST - Pain at home in sickle cell disease: an underrecognized problem T2 - J Pediatr Hematol Oncol TI - Pain at home in sickle cell disease: an underrecognized problem VL - 24 ID - 3324 ER - TY - JOUR AB - QUESTIONS UNDER STUDY/PRINCIPLES: Non-pharmacologic analgesia has been demonstrated to alleviate pain and distress in invasive procedures. Nevertheless, the practice has not been adopted widely in paediatric departments because nurses are often too busy to perform a time consuming procedure. METHODS: Three hundred patients (8-9 years) requiring venepuncture for intravenous treatment were randomized into audiovisual distraction group (n = 100, watching cartoon films), intervention group (n = 100, receiving psychological intervention) and control group (n = 100, without any intervention). RESULTS: There was no significant difference (P>0.05) between the audiovisual distraction and the intervention groups for cooperation, venepuncture times and pain intensity (assessed with visual analogue scale, VAS). However, cooperation in the control group was more passive than in the intervention group (P <0.05) but not apparently different to the audiovisual distraction group (P >0.05). Venepuncture time was significantly higher in the control group than in the other two groups (P <0.05). Venepuncture caused moderate pain in children (VAS score: 5.22 +/- 2.53 in the control group). VAS scores indicated that procedures were more painful in the control group than in the audiovisual distraction or the intervention group (VAS score: 4.55 +/- 2.26 and 4.38 +/- 2.32 in the audiovisual distraction and intervention groups respectively, P <0.05). CONCLUSIONS: Audiovisual distraction was demonstrated to be effective in reducing self-reported pain, improving patient cooperation and increasing success rate in venepuncture procedures and was as successful as routine psychological intervention. It is highly recommended as an effective, labour saving and easy to administer analgesia and should be used to help prevent pain from venepuncture in school age children. AU - Wang, Zi-Xuan AU - Sun, Li-Hui AU - Chen, Ai-Ping DA - 2008/10/04/ DO - 2008/39/smw-12224 DP - PubMed IS - 39-40 J2 - Swiss Med Wkly KW - Child Child, Hospitalized Cooperative Behavior Female Humans Infusions, Intravenous Male Nurse-Patient Relations Patient Compliance Phlebotomy Television LA - eng PY - 2008 SN - 1424-7860 SP - 579-584 ST - The efficacy of non-pharmacological methods of pain management in school-age children receiving venepuncture in a paediatric department T2 - Swiss Medical Weekly TI - The efficacy of non-pharmacological methods of pain management in school-age children receiving venepuncture in a paediatric department: a randomized controlled trial of audiovisual distraction and routine psychological intervention UR - http://www.ncbi.nlm.nih.gov/pubmed/18853287 VL - 138 ID - 110 ER - TY - JOUR AB - Questions under study/principles: Non-pharmacologic analgesia has been demonstrated to alleviate pain and distress in invasive procedures. Nevertheless, the practice has not been adopted widely in paediatric departments because nurses are often too busy to perform a time consuming procedure. Methods: Three hundred patients (8-9 years) requiring venepuncture for intravenous treatment were randomized into audiovisual distraction group (n = 100, watching cartoon films), intervention group (n = 100, receiving psychological intervention) and control group (n = 100, without any intervention). Results: There was no significant difference (P >0.05) between the audiovisual distraction and the intervention groups for cooperation, venepuncture times and pain intensity (assessed with visual analogue scale, VAS). However, cooperation in the control group was more passive than in the intervention group (P <0.05) but not apparently different to the audiovisual distraction group (P >0.05). Venepuncture time was significantly higher in the control group than in the other two groups (P <0.05). Venepuncture caused moderate pain in children (VAS score: 5.22 +/- 2.53 in the control group). VAS scores indicated that procedures were more painful in the control group than in the audiovisual distraction or the intervention group (VAS score: 4.55 +/- 2.26 and 4.38 +/- 2.32 in the audiovisual distraction and intervention groups respectively, P <0.05). Conclusions: Audiovisual distraction was demonstrated to be effective in reducing self-reported pain, improving patient cooperation and increasing success rate in venepuncture procedures and was as successful as routine psychological intervention. It is highly recommended as an effective, labour saving and easy to administer analgesia and should be used to help prevent pain from venepuncture in school age children. AN - WOS:000259834700004 AU - Wang, Z. X. AU - Sun, L. H. AU - Chen, A. P. DA - Oct IS - 39-40 N1 - Wang, Zi-Xuan Sun, Li-Hui Chen, Ai-Ping Wang, Zi Xuan/AAT-6855-2020 Wang, Zi Xuan/0000-0002-0854-5895 1424-3997 PY - 2008 SN - 1424-7860 SP - 579-584 ST - The efficacy of non-pharmacological methods of pain management in school age children receiving venepuncture in a paediatric department: a randomized controlled trial of audiovisual distraction and routine psychological intervention T2 - Swiss Medical Weekly TI - The efficacy of non-pharmacological methods of pain management in school age children receiving venepuncture in a paediatric department: a randomized controlled trial of audiovisual distraction and routine psychological intervention UR - ://WOS:000259834700004 VL - 138 ID - 2633 ER - TY - JOUR AB - Objective. To compare sleep disturbances and neurobehavioral function in children. with juvenile idiopathic arthritis (JIA) to age- and sex-matched control children. Methods. Children (n = 116) ages 6-11 years with (n = 70) and without (n = 46) JIA and their parents participated. Parents completed questionnaires on sleep habits, sleep behavior, and school competence of their children; children completed computerized neurobehavioral performance tests. Results. Compared to control children, children with JIA had a statistically significant (P < 0.001) greater mean overall sleep disturbance score and higher scores on 6 of 8 subscales (all P < 0.03) of the Children's Sleep Habits Questionnaire (CSHQ). There were no group differences on neurobehavioral performance test scores. However, regardless of group, children with an overall CSHQ score above an established cutoff for clinically significant sleep disturbances had slower mean simple reaction time (t = -2.2, P < 0.03) and mean 5-choice reaction time (t = -2.3, P < 0.02) compared to those below the cutoff score. The CHSQ overall sleep disturbance score predicted reaction time (P < 0.009) after controlling for age, intelligence quotient, medication, and group. Conclusion. Children with JIA have more parent-reported sleep disturbances, but performed as well as control children on a series of standardized computer tests of neurobehavioral performance. Children with more disturbed sleep had slower reaction times. AN - WOS:000292809200012 AU - Ward, T. M. AU - Ringold, S. AU - Metz, J. AU - Archbold, K. AU - Lentz, M. AU - Wallace, C. A. AU - Landis, C. A. DA - Jul DO - 10.1002/acr.20469 IS - 7 N1 - Ward, Teresa M. Ringold, Sarah Metz, Jonika Archbold, Kristen Lentz, Martha Wallace, Carol A. Landis, Carol A. Hash, Jonika/AAV-1235-2020 Hash, Jonika/0000-0001-7710-5220 2151-4658 PY - 2011 SN - 2151-464X SP - 1006-1012 ST - Sleep Disturbances and Neurobehavioral Functioning in Children With and Without Juvenile Idiopathic Arthritis T2 - Arthritis Care & Research TI - Sleep Disturbances and Neurobehavioral Functioning in Children With and Without Juvenile Idiopathic Arthritis UR - ://WOS:000292809200012 VL - 63 ID - 2485 ER - TY - JOUR AB - Although essential for providing optimal adolescent patient support, knowledge of the impact of Marfan syndrome in adolescence is limited. To explore adolescents' perceived impact of Marfan syndrome on (physical) functioning (activities, participation), disability (limitations, restrictions), contextual factors and support needs, we interviewed 19 adolescents with Marfan syndrome. Audio-recordings were transcribed, coded and analysed using thematic analysis. Identified themes were "difficulties in keeping up with peers" and "being and feeling different from peers". Furthermore, an adolescent Marfan syndrome-specific International Classification of Functioning, Disability and Health for Children and Youth (ICF-CY) model derived from the data describing the adolescent perceived impact of Marfan syndrome on functioning, disability and its contextual factors. Adolescents perceived problems in keeping up with peers in school, sports, leisure and friendships/relationships, and they could not meet work requirements. Moreover, participants perceived to differ from peers due to their appearance and disability. Contextual factors: coping with Marfan syndrome, self-esteem/image, knowledge about Marfan syndrome, support from family/friends/teachers, ability to express needs and peer-group acceptation acted individually as barrier or facilitator for identified themes. Conclusion: Adolescents with Marfan syndrome perceived limitations and restrictions in (physical) functioning. They perceived problems in keeping up with peers and perceived to differ from peers due to their appearance and disability. This warrants awareness and tailored physical, psychosocial, educational and environmental support programmes to improve (physical) functioning and empowerment of adolescents with Marfan syndrome.What is known:center dot Marfan syndrome is a hereditary connective tissue disorder.center dot Marfan syndrome affects multiple systems.What is new:center dot Adolescents with Marfan syndrome perceive (1) problems in keeping up with peers in school, sports, leisure, friendships/relationships and work (2) to differ from peers due to their appearance and disability.center dot An adolescent Marfan syndrome-specific International Classification of Functioning, Disability and Health for Children and Youth model derived from the data describing the adolescent perceived impact of Marfan syndrome on functioning, disability and contextual factors. AN - WOS:000490890000001 AU - Warnink-Kavelaars, J. AU - Beelen, A. AU - Goedhart, Tmhj AU - de Koning, L. E. AU - Nollet, F. AU - Alsem, M. W. AU - Menke, L. A. AU - Engelbert, R. H. H. DA - Dec DO - 10.1007/s00431-019-03469-7 IS - 12 N1 - Warnink-Kavelaars, Jessica Beelen, Anita Goedhart, Tine M. H. J. de Koning, Lisanne E. Nollet, Frans Alsem, Mattijs W. Menke, Leonie A. Engelbert, Raoul H. H. Warnink-Kavelaars, Jessica/0000-0002-7597-3443 1432-1076 PY - 2019 SN - 0340-6199 SP - 1883-1892 ST - Marfan syndrome in adolescence: adolescents' perspectives on (physical) functioning, disability, contextual factors and support needs T2 - European Journal of Pediatrics TI - Marfan syndrome in adolescence: adolescents' perspectives on (physical) functioning, disability, contextual factors and support needs UR - ://WOS:000490890000001 VL - 178 ID - 1877 ER - TY - JOUR AB - BACKGROUND: Low back pain (LBP) and motion alterations can occur in athletes who engage in high-speed throwing motions. The relationship between LBP and shooting motion in lacrosse players is not yet known. PURPOSE: To quantify the effects of LBP on key kinematic parameters of the lacrosse shot and determine the contribution of the severity of LBP on specific kinematic parameters of the shooting motion. STUDY DESIGN: Controlled laboratory study. METHODS: High school and collegiate players (N = 24) were stratified into 2 groups based on back pain symptoms (LBP or no pain). Three-dimensional motion capture of overhead throws was used to collect data on knee, pelvis, trunk, and shoulder kinematics as well as crosse stick (the stick capped with a strung net) and ball speed. RESULTS: Mean low back numeric pain rating scale (NRSpain) score was 2.9. Knee flexion at ball release was greater in the LBP than no pain group, indicating a more bent knee (P = .04). The LBP group demonstrated less angular velocity transfer from pelvis to trunk than the no pain group (P = .05). Total range of motion of the pelvis and shoulders during the shot and follow-through were less in the LBP group than the no pain group (83.6° ± 24.5° vs 75.9° ± 24.5°, P = .05). Age- and sex-adjusted regression analyses revealed that the low back NRSpain rating contributed 6.3% to 25.0% of the variance to the models of shoulder transverse rotation range of motion, trunk and shoulder rotation angular velocities, and knee flexion angle (P < .05). CONCLUSION: LBP severity significantly contributes to trunk and shoulder motion restriction during lacrosse shooting. Inclusion of lumbopelvic and core training and prehabilitation programs for high school and collegiate players may reduce pain in affected players as well as help them to attain appropriate motion parameters and avoid secondary musculoskeletal injuries. CLINICAL RELEVANCE: This research identified a prehabilitation need in the understudied lacrosse population. Therapeutic strategies can be developed to strengthen the throwing motion, which could control mechanical loading patterns on the low back and minimize pain symptoms in players with chronic LBP. AD - Department of Orthopaedics and Rehabilitation, Division of Research, Interdisciplinary Center for Musculoskeletal Training and Research, University of Florida, Gainesville, Florida, USA. AN - 27504465 AU - Wasser, J. G. AU - Chen, C. AU - Vincent, H. K. C2 - PMC4962339 DA - Jul DO - 10.1177/2325967116657535 DP - NLM ET - 2016/08/10 IS - 7 KW - biomechanics lacrosse lumbar motion analysis/kinesiology publication of this contribution. LA - eng N1 - 2325-9671 Wasser, Joseph G Chen, Cong Vincent, Heather K Journal Article Orthop J Sports Med. 2016 Jul 25;4(7):2325967116657535. doi: 10.1177/2325967116657535. eCollection 2016 Jul. PY - 2016 SN - 2325-9671 (Print) 2325-9671 SP - 2325967116657535 ST - Kinematics of Shooting in High School and Collegiate Lacrosse Players With and Without Low Back Pain T2 - Orthop J Sports Med TI - Kinematics of Shooting in High School and Collegiate Lacrosse Players With and Without Low Back Pain VL - 4 ID - 4145 ER - TY - JOUR AB - The aim of this thesis was to investigate a consecutive series of patients with craniomandibular disorders (CMD), mainly functional disturbances of the masticatory system, in order to evaluate symptoms, the treatment outcome and the long-term prognosis in relation to different background factors. All 350 patients who came to a TMJ-clinic during a specific time period were included. 68% of the patients were women. The ages of the patients ranged between 12 and 80 years, with a mean of 39.9 years for the women and 38.3 for the men. At the first visit, the patients were given a self-administered questionnaire with 25 standardised questions. After 2 1/2 years, the records of the patients were examined for clinical findings, diagnoses and treatment. After about 4 years, a questionnaire, similar to the original one, was sent to a young and an old group of the patients to register present symptoms and need of treatment. Finally a clinical follow-up was performed in those who had reported that they wanted more treatment and, for comparison, in a group who had reported that they did not. The symptomatology was extremely varied in this group of 350 CMD patients. Headache, pain on mandibular movements and TMJ sounds were the most frequently reported symptoms. The significant correlation found between the severity of reported symptoms and the clinical dysfunction index (Di) was best explained by muscle tenderness on palpation. The dental status varied greatly among the patients and it was not significantly correlated to Di. The number of visits and length of the treatment period, factors that varied widely, were correlated to variables indicating severity of signs and symptoms at the first visit. Otherwise it was difficult to predict the treatment outcome, even when patients were divided into subgroups. Only one variable from the original questionnaire, duration of initial symptoms, and none from the first clinical examination, was significantly correlated to the treatment outcome at the 4-year follow-up. The mean number of days of sick-leave in the patients was correlated to Di, and it decreased after stomatognathic treatment. This series of studies has shown that patients with CMD are extremely heterogeneous in many respects, e.g. regarding symptoms, diagnosis and outcome of treatment. AD - Department of Stomatognathic Physiology, Faculty of Odontology, University of Göteborg, Sweden. AN - 3194852 AU - Wedel, A. DP - NLM ET - 1988/01/01 KW - Absenteeism Adolescent Adult Aged Aged, 80 and over Child Female Follow-Up Studies Humans Longitudinal Studies Male Middle Aged Prognosis Temporomandibular Joint Dysfunction Syndrome/diagnosis/*physiopathology/therapy LA - eng N1 - Wedel, A Comparative Study Journal Article Research Support, Non-U.S. Gov't Sweden Swed Dent J Suppl. 1988;55:1-51. PY - 1988 SN - 0348-6672 (Print) 0348-6672 SP - 1-51 ST - Heterogeneity of patients with craniomandibular disorders. A longitudinal study T2 - Swed Dent J Suppl TI - Heterogeneity of patients with craniomandibular disorders. A longitudinal study VL - 55 ID - 3460 ER - TY - JOUR AB - BACKGROUND: A small minority of sickle cell disease patients accounts for the majority of inpatient hospital days. Admitted as often as several times a month, over successive years, this cohort of patients has not been studied in depth despite their disproportionate contribution to inpatient hospital costs in sickle cell disease. OBJECTIVE: To characterize the subjective experience of extremely high hospital use in patients with sickle cell disease, and generate hypotheses about the antecedents and consequences of this phenomenon. DESIGN: Qualitative study involving in-depth, open-ended interviews using a standardized interview guide. SETTING: A single urban academic medical center. PARTICIPANTS: Eight individuals, of varying age and gender, identified as the sickle cell disease patients who are among the highest hospital use patients over a 3-year period. RESULTS: A common narrative emerged from the interview transcripts. Participants were exposed to the hospital environment and intravenous (IV) opioids at a young age, and this exposure was associated with extremely high hospital use in adulthood, evident in descriptions of multiple dimensions of their lives: pain and opioid medication use, interpersonal relationships, and personal development. CONCLUSIONS: Our results suggest a systematic, self-reinforcing process of isolation from mainstream society, support structures, and caregivers, based on increasing hospitalization, growing dependency on opioid medications, as well as missed developmental milestones. Further study and interventions should be geared towards breaking this spiraling cycle with long-term strategies in disease management and social integration. Journal of Hospital Medicine 2013. (c) 2012 Society of Hospital Medicine AN - WOS:000313121800008 AU - Weisberg, D. AU - Balf-Soran, G. AU - Becker, W. AU - Brown, S. E. AU - Sledge, W. DA - Jan DO - 10.1002/jhm.1987 IS - 1 N1 - Weisberg, Daniel Balf-Soran, Gabriela Becker, William Brown, Shan-Estelle Sledge, William Becker, William/0000-0002-0788-1467 1553-5606 PY - 2013 SN - 1553-5592 SP - 42-46 ST - "I'm Talking About Pain": Sickle cell disease patients with extremely high hospital use T2 - Journal of Hospital Medicine TI - "I'm Talking About Pain": Sickle cell disease patients with extremely high hospital use UR - ://WOS:000313121800008 VL - 8 ID - 2400 ER - TY - JOUR AB - Disrupted somatosensory processing characterized by over- or under- responsiveness to environmental stimuli plays an important, yet often overlooked, role in typical development and is aberrant in various neurodevelopmental disorders. These dysfunctional somatosensory processes have been conceptualized as an entity termed somatosensory dysregulation (SMD). Since Tourette syndrome (TS) is a prototypical example of developmental psychopathological disorder, we hypothesised that SMD would be a feature found in children suffering from the disorder. Ninety-two subjects representing consecutive admissions to a tertiary paediatric Tourette syndrome clinic were admitted to the study. Comorbid conditions included ADHD, depression, anxiety disorder, and OCD. For purposes of the study, patients completed a battery of self-, caregiver-, and clinician-rated psychological instruments measuring TS core symptoms and comorbidities and quality of life. Sensory modulation was measured by self-report and by objective measures such as stimulation with Von Frey filaments. Almost 50% of the cohort had no SMD. Of the remainder, 14 (15%) had suspected SMD and 32 (34.8%) had SMD. SMD was significantly more common and severe when there were comorbidities. The presence of SMD was associated with more severe impairments in quality of life and less participation in daily activities. The SMD, as measured by subjective measures but not by objective, is probably more associated with central processing rather than peripheral perception. AN - WOS:000435405600008 AU - Weisman, H. AU - Parush, S. AU - Apter, A. AU - Fennig, S. AU - Benaroya-Milshtein, N. AU - Steinberg, T. DA - Jul DO - 10.1007/s00702-018-1858-4 IS - 7 N1 - Weisman, Hana Parush, Shula Apter, Alan Fennig, Silvana Benaroya-Milshtein, Noa Steinberg, Tamar 1435-1463 PY - 2018 SN - 0300-9564 SP - 1077-1085 ST - A study of sensory dysregulation in children with tic disorders T2 - Journal of Neural Transmission TI - A study of sensory dysregulation in children with tic disorders UR - ://WOS:000435405600008 VL - 125 ID - 2010 ER - TY - JOUR AB - Background: Medical rehabilitation aims at an improvement in function, capacity and participation. For the rehabilitation of spinal deformities, the goal is to maintain function and prevent secondary symptoms in the short and long-term. In patients with scoliosis, predictable signs and symptoms include pain and reduced pulmonary function. Materials and methods: A Pub Med review was completed in order to reveal substantial evidence for inpatient rehabilitation as performed in Germany. No evidence has been found in general to support claims for actual inpatient rehabilitation programmes as used today. Nevertheless, as there is some evidence that inpatient rehabilitation may be beneficial to patients with spinal deformities complicated by certain additional conditions, the body of evidence there is for conservative treatment of spinal deformities has been reviewed in order to allow suggestions for outpatient conservative treatment and inpatient rehabilitation. Discussion: Today, for both children and adolescents, we are able to offer intensive rehabilitation programmes lasting three to five days, which enable the patients to acquire the skills necessary to prevent postures fostering scoliosis in everyday life without missing too much of school teaching subjects at home. The secondary functional impairments adult scoliosis patients might have, as in the opinion of the author, still today require the time of 3-4 weeks in the clinical in-patient setting. Time to address psychosocial as well as somatic limitations, namely chronic pains and cardiorespiratory malfunction is needed to preserve the patients working capability in the long-term. Conclusion: Outpatient treatment/rehabilitation is sufficient for adolescents with spinal deformities. Inpatient rehabilitation is recommended for patients with spinal deformities and pain or severe restrictive ventilation disorder. AN - WOS:000214917600028 AU - Weiss, H. R. C7 - 28 DO - 10.1186/1748-7161-5-28 N1 - Weiss, Hans-Rudolf PY - 2010 SN - 2397-1789 ST - Spinal deformities rehabilitation - state of the art review T2 - Scoliosis and Spinal Disorders TI - Spinal deformities rehabilitation - state of the art review UR - ://WOS:000214917600028 VL - 5 ID - 2580 ER - TY - JOUR AB - Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease in childhood. Persistent pain is the most common and distressing symptom of JIA, and pain in childhood arthritis is multifactorial. Children and adolescents with persistent pain due to JIA experience significantly more problems with physical, emotional, social, and school functioning than healthy individuals. Assessment of pain at each office visit is the cornerstone of effective pain management and should include an evaluation of pain intensity, interference, and coping. Following the biopsychosocial model of pain management, a multi-modal approach is recommended for pain control in children with arthritis. Pharmacologic strategies for the treatment of pain in JIA include aggressive treatment of the underlying disease as well as the use of acetaminophen and systemic and topical non-steroidal anti-inflammatory drugs for persistent mild pain. Opioids can be considered in the case of moderate to severe persistent pain. Physical therapies and psychological interventions such as cognitive behavioral therapy are also key components of pain management in JIA. AN - WOS:000345750800003 AU - Weiss, J. E. AU - Luca, N. J. C. AU - Boneparth, A. AU - Stinson, J. DA - Dec DO - 10.1007/s40272-014-0094-0 IS - 6 N1 - Weiss, Jennifer E. Luca, Nadia J. C. Boneparth, Alexis Stinson, Jennifer Weiss, Jennifer E./AAT-8797-2020 1179-2019 PY - 2014 SN - 1174-5878 SP - 473-481 ST - Assessment and Management of Pain in Juvenile Idiopathic Arthritis T2 - Pediatric Drugs TI - Assessment and Management of Pain in Juvenile Idiopathic Arthritis UR - ://WOS:000345750800003 VL - 16 ID - 2275 ER - TY - JOUR AB - Chronic musculoskeletal pain (CMP) is one of the main reasons for referral to a pediatric rheumatologist and is the third most common cause of chronic pain in children and adolescents. Causes of CMP include amplified musculoskeletal pain, benign limb pain of childhood, hypermobility, overuse syndromes, and back pain. CMP can negatively affect physical, social, academic, and psychological function, so it is essential that clinicians know how to diagnose and treat these conditions. This article provides an overview of the epidemiology and impact of CMP, the steps in a comprehensive pain assessment, and the management of the most common CMPs. AN - WOS:000442707600012 AU - Weiss, J. E. AU - Stinson, J. N. DA - Aug DO - 10.1016/j.pcl.2018.04.004 IS - 4 N1 - Weiss, Jennifer E. Stinson, Jennifer N. Weiss, Jennifer E./AAT-8797-2020 1557-8240 PY - 2018 SN - 0031-3955 SP - 801-+ ST - Pediatric Pain Syndromes and Noninflammatory Musculoskeletal Pain T2 - Pediatric Clinics of North America TI - Pediatric Pain Syndromes and Noninflammatory Musculoskeletal Pain UR - ://WOS:000442707600012 VL - 65 ID - 1999 ER - TY - JOUR AB - BACKGROUND: Knee injuries are prevalent among a variety of competitive sports and can impact an athlete's ability to continue to participate in their sport or, in the worst case, end an athlete's career. OBJECTIVE: The aim was to evaluate biomechanics associated with both patellofemoral pain syndrome (PFPS) and anterior cruciate ligament (ACL) injuries (in sports involving landing, change in direction, or rapid deceleration) across the three time points frequently reported in the literature: pre-injury, at the time of injury, and following injury. METHODS: A search of the literature was conducted for research evaluating biomechanics associated with ACL injury and PFPS. The Web of Science, SPORTDiscus, EBSCO, PubMed, and CINAHL databases, to March 2015, were searched, and journal articles focused on ACL injuries and PFPS in sports that met the inclusion criteria were reviewed. The search methodology was created with the intent of extracting case-control, case, and cohort studies of knee injury in athletic populations. The search strategy was restricted to only full-text articles published in English. These articles were included in the review if they met all of the required selection criteria. The following inclusion criteria were used: (1) The study must report lower extremity biomechanics in one of the following settings: (a) a comparison of currently injured and uninjured participants, (b) a prospective study evaluating risk factors for injury, or (c) a study reporting on the injury event itself. (2) The study must include only currently active participants who were similar at baseline (i.e. healthy, high school level basketball players currently in-season) and include biomechanical analysis of either landing, change in direction, or rapid deceleration. (3) The study must include currently injured participants. The studies were graded on the basis of quality, which served as an indication of risk of bias. An adapted version of the 'Strengthening the Reporting of Observational Studies in Epidemiology' (STROBE) guidelines was used to rate observational research. RESULTS: Fifteen journal articles focusing on ACL injuries and PFPS in sports met the inclusion criteria. These included three associated with both ACL injuries and PFPS across multiple time points. There was limited evidence for an association between ankle biomechanics and knee injury, with only one ACL injury study identifying decreased plantar flexion in association with injury. LIMITATIONS: Only prospective studies can determine biomechanical risk factors associated with ACL injuries and PFPS. Case studies and case-control studies do not allow for the determination of risk factors associated with both ACL injuries and PFPS as there is no certainty regarding the presence of the observed biomechanics prior to the onset of injury. Further, each study design has its own set of limitations. Lastly, the majority of the studies included in this review had adult female participants. CONCLUSION: By evaluating several different study designs looking at knee injuries during high-risk manoeuvres, we were able to obtain a holistic perspective of biomechanics associated with PFPS and ACL injuries. Looking at different biomechanical research approaches allowed us to assess not only the mechanism of injury, but also to look for commonalities in biomechanics (in particular, altered frontal plane mechanics at the knee and altered sagittal plane mechanics at the knee and hip) between injured and uninjured participants pre-injury, at the time of injury, and following injury, to better understand potential causes of PFPS and ACL injury. Development of injury prevention programmes should focus on correcting these mechanics observed across the three time points during high-risk manoeuvres as this may help decrease the prevalence of ACL injury and PFPS. Programmes focusing not only on neuromuscular training, but also skill-specific training focused on correcting mechanics during these high-risk manoeuvres may be of greatest benefit regarding prevention. Future research should consider the impact of cumulative loading on knee injury risk. Additionally, better techniques for assessing mechanics in-game are needed in order to facilitate injury prevention and screening strategies. AD - Faculty of Health and Environmental Science, Sports Performance Research Institute New Zealand (SPRINZ), School of Sport and Recreation, Auckland University of Technology, Auckland, New Zealand. kweiss@aut.ac.nz. Faculty of Health and Environmental Science, Sports Performance Research Institute New Zealand (SPRINZ), School of Sport and Recreation, Auckland University of Technology, Auckland, New Zealand. AN - 26130304 AU - Weiss, K. AU - Whatman, C. DA - Sep DO - 10.1007/s40279-015-0353-4 DP - NLM ET - 2015/07/02 IS - 9 KW - Adolescent Adult *Anterior Cruciate Ligament Injuries Athletic Injuries/*physiopathology Biomechanical Phenomena Female Humans Knee Injuries/*physiopathology Male Middle Aged Patellofemoral Pain Syndrome/*physiopathology Young Adult LA - eng N1 - 1179-2035 Weiss, Kaitlyn Orcid: 0000-0002-4224-6522 Whatman, Chris Journal Article Review New Zealand Sports Med. 2015 Sep;45(9):1325-1337. doi: 10.1007/s40279-015-0353-4. PY - 2015 SN - 0112-1642 SP - 1325-1337 ST - Biomechanics Associated with Patellofemoral Pain and ACL Injuries in Sports T2 - Sports Med TI - Biomechanics Associated with Patellofemoral Pain and ACL Injuries in Sports VL - 45 ID - 4089 ER - TY - JOUR AB - Objectives The aims of this study were: (1) investigate relations between pain acceptance, depressive symptoms, catastrophizing, and functional disability in pediatric patients in an interdisciplinary chronic pain rehabilitation program, (2) examine changes in acceptance from pre- to posttreatment, and (3) test if changes in acceptance predict changes in depressive symptoms, catastrophizing, and functional disability from pre- to posttreatment. Methods 112 participants, ages 11-18 years, completed the Chronic Pain Acceptance Questionnaire, Adolescent Version, Center for Epidemiological Studies-Depression-Children's Scale, Pain Catastrophizing Scale for Children, and Functional Disability Inventory on admission to and completion of the program. Results Significant and strong relations between acceptance, depression, catastrophizing, and functional disability were demonstrated. Participants demonstrated significant increases in acceptance and decreases in depression, catastrophizing, and functional disability. Finally, changes in acceptance significantly predicted changes in depressive symptoms, catastrophizing, and functional disability. Conclusions Pain acceptance is an important variable in the treatment of pediatric chronic pain. AN - WOS:000322574100007 AU - Weiss, K. E. AU - Hahn, A. AU - Wallace, D. P. AU - Biggs, B. AU - Bruce, B. K. AU - Harrison, T. E. DA - Aug DO - 10.1093/jpepsy/jst028 IS - 7 N1 - Weiss, Karen E. Hahn, Amy Wallace, Dustin P. Biggs, Bridget Bruce, Barbara K. Harrison, Tracy E. Wallace, Dustin P/L-6401-2016 Wallace, Dustin P/0000-0002-1592-9686 1465-735x PY - 2013 SN - 0146-8693 SP - 756-765 ST - Acceptance of Pain: Associations With Depression, Catastrophizing, and Functional Disability Among Children and Adolescents in an Interdisciplinary Chronic Pain Rehabilitation Program T2 - Journal of Pediatric Psychology TI - Acceptance of Pain: Associations With Depression, Catastrophizing, and Functional Disability Among Children and Adolescents in an Interdisciplinary Chronic Pain Rehabilitation Program UR - ://WOS:000322574100007 VL - 38 ID - 2361 ER - TY - JOUR AB - Objective. Despite ample research documenting deficits in executive functioning for adults with chronic pain, the literature on pediatric patients with chronic pain is limited and provides mixed results. The current study sought to further investigate the nature of executive dysfunction in this population and also examine the relationships between pain intensity, duration, and catastrophizing with sustained attention, working memory, and self-and parent-report of executive functioning. Settings. Pediatric pain clinic and rehabilitation program. Participants. Forty adolescents with chronic pain and their parents participated in this study. Methods. Participants completed neuropsychological measures and standardized self-report questionnaires during a 45-to 60-minute testing session. Results. Fifty percent of this sample of adolescents with chronic pain demonstrated significant difficulties on at least one measure, with nine participants indicating difficulties on multiple measures. Pain significantly increased during the testing session. Pain variables of intensity, duration, and catastrophizing are related to sustained attention and working memory. Conclusions. This study adds support to previous findings suggesting subclinical struggles with executive functioning for adolescents with chronic pain. One-half of the sample indicated difficulties in either sustained attention and/or working memory. Future studies that would more thoroughly examine more complex executive functioning skills in this population would be helpful to further guide multi-disciplinary treatment of these patients, particularly regarding whether or not school accommodations are warranted. AN - WOS:000422842800008 AU - Weiss, K. E. AU - Harbeck-Weber, C. AU - Zaccariello, M. J. AU - Kimondo, J. N. AU - Harrison, T. E. AU - Bruce, B. K. DA - Jan DO - 10.1093/pm/pnx020 IS - 1 N1 - Weiss, Karen E. Harbeck-Weber, Cynthia Zaccariello, Michael J. Kimondo, Jacqueline N. Harrison, Tracy E. Bruce, Barbara K. 1526-4637 PY - 2018 SN - 1526-2375 SP - 60-67 ST - Executive Functioning in Pediatric Chronic Pain: Do Deficits Exist? T2 - Pain Medicine TI - Executive Functioning in Pediatric Chronic Pain: Do Deficits Exist? UR - ://WOS:000422842800008 VL - 19 ID - 2054 ER - TY - JOUR AB - A meta-analysis of child and adolescent psychotherapy outcome research tested previous findings using a new sample of 150 outcome studies and weighted least squares methods. The overall mean effect of therapy was positive and highly significant. Effects were more positive for behavioral than for nonbehavioral treatments, and samples of adolescent girls showed better outcomes than other Age X Gender groups. Paraprofessionals produced larger overall treatment effects than professional therapists or students, but professionals produced larger effects than paraprofessionals in treating overcontrolled problems (e.g., anxiety and depression). Results supported the specificity of treatment effects: Outcomes were stronger for the particular problems targeted in treatment than for problems not targeted. The findings shed new light on previous results and raise significant issues for future study. AN - WOS:A1995QX81500007 AU - Weisz, J. R. AU - Weiss, B. AU - Han, S. S. AU - Granger, D. A. AU - Morton, T. DA - May DO - 10.1037/0033-2909.117.3.450 IS - 3 N1 - Weisz, jr weiss, b han, ss granger, da morton, t Fahimifar, Sepideh/M-5303-2019; White, Howard D/A-7034-2009; Espinosa, Daniel/B-7285-2012 1939-1455 PY - 1995 SN - 0033-2909 SP - 450-468 ST - EFFECTS OF PSYCHOTHERAPY WITH CHILDREN AND ADOLESCENTS REVISITED - A METAANALYSIS OF TREATMENT OUTCOME STUDIES T2 - Psychological Bulletin TI - EFFECTS OF PSYCHOTHERAPY WITH CHILDREN AND ADOLESCENTS REVISITED - A METAANALYSIS OF TREATMENT OUTCOME STUDIES UR - ://WOS:A1995QX81500007 VL - 117 ID - 2938 ER - TY - JOUR AB - BACKGROUND: Soft tissue musculoskeletal injuries make up a high proportion of all work-related injuries in construction. Data from Workers' Compensation claims indicate that strains and sprains are the leading compensable injury for construction workers. This study describes the consequences of soft tissue musculoskeletal injuries for construction workers, and assesses the persistence of symptoms after an injury and the impact of that injury on return to work. METHODS: Through an Emergency Department surveillance system [Hunting et al., 1994a], we recorded 176 construction worker visits, from 5/01/93 through 2/28/95, for strains, sprains, joint injury or pain, tendinitis, dislocations, hernias, or other musculoskeletal injuries excluding fractures. Telephone interviews were conducted several months after workers had visited the emergency room for a musculoskeletal injury. RESULTS: Seventy individuals were interviewed about the long-term impacts of 72 incidents that had resulted in work-related musculoskeletal injuries. For 46 (62%) of the 74 diagnoses, problems continued beyond two months. The likelihood of problems continuing more than two months varied considerably by body location of injury. Hispanic workers and older workers were more likely to have continuing symptoms. Eleven of the 45 construction workers with symptoms persisting longer than two months were not employed at the time of the interview. Only 11 of the 45 workers with ongoing symptoms told us that modifications had been made to their jobs to accommodate their symptoms. About one-quarter of these 45 subjects reported substantial effects on home or work life. CONCLUSIONS: Acute musculoskeletal injuries in construction workers frequently result in chronic symptoms, and those with chronic symptoms report substantial effects of the injury on their quality of life. Job accommodations were made in a minority of these injuries. These findings point to the need for heightened efforts for injury prevention in this industry. AD - Section of Occupational and Environmental Medicine, Department of Medicine, Washington Hospital Center, Washington, DC 20010, USA. lxw6@mhg.edu AN - 10506735 AU - Welch, L. S. AU - Hunting, K. L. AU - Nessel-Stephens, L. DA - Nov DO - 10.1002/(sici)1097-0274(199911)36:5<532::aid-ajim5>3.0.co;2-9 DP - NLM ET - 1999/10/03 IS - 5 KW - Absenteeism Adolescent Adult Age Factors Arthralgia/epidemiology Bone and Bones/*injuries Chronic Disease District of Columbia/epidemiology Emergency Service, Hospital/statistics & numerical data Employment Female Follow-Up Studies Hernia/epidemiology Hispanic Americans/statistics & numerical data Humans Joint Dislocations/epidemiology Joints/injuries Male Middle Aged Muscle, Skeletal/*injuries Occupational Diseases/*epidemiology Population Surveillance Quality of Life Soft Tissue Injuries/*epidemiology Sprains and Strains/epidemiology Tendinopathy/epidemiology LA - eng N1 - Welch, L S Hunting, K L Nessel-Stephens, L CCU306169/PHS HHS/United States Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. United States Am J Ind Med. 1999 Nov;36(5):532-40. doi: 10.1002/(sici)1097-0274(199911)36:5<532::aid-ajim5>3.0.co;2-9. PY - 1999 SN - 0271-3586 (Print) 0271-3586 SP - 532-40 ST - Chronic symptoms in construction workers treated for musculoskeletal injuries T2 - Am J Ind Med TI - Chronic symptoms in construction workers treated for musculoskeletal injuries VL - 36 ID - 3618 ER - TY - JOUR AB - Obesity has been identified as an epidemic in the United States for more than two decades and yet the numbers of overweight and obese adults and children continue to grow. Currently, the rates of both overweight and obesity in the US are 61% and 14% in adults and children, respectively. Among US adults aged 20-74 years, the prevalence of overweight (defined as BMI 25.0-29.9) has increased from 33% in 1980 to 35% of the population in 1999. In the same population, obesity (defined as BMI greater than or equal to 30) has nearly doubled from approximately 15% in 1980 to an estimated 27% in 1999. The percentage of children and adolescents who are defined as overweight has more than doubled since the early 1970s. About 14% of children and adolescents are now seriously overweight. Obesity burdens the health care system, strains economic resources, and has far reaching social consequences. The disease is associated with several serious health conditions including: type 2 diabetes mellitus, heart disease, high blood pressure and stroke. It is also linked to higher rates of certain types of cancer. Obesity is an independent risk factor for heart disease, hypoxia, sleep apnea, hernia, and arthritis. Obesity is the seventh leading cause of death in the US. The total cost of overweight and obesity by some estimates is $100 billion annually. Others put the cost of health care for obesity alone at $70 billion. Other annual costs associated with obesity are 40 million workdays of productivity lost, 63 million doctors' office visits made, and 239 million restricted activity days and 90 million bed-bound days. Emotional suffering may be among the most painful aspects of obesity. American society emphasizes physical appearance and often equates attractiveness with slimness, especially for women. Such messages may be devastating to overweight people. Many think that obese individuals are gluttonous, lazy, or both, even though this is not true. As a result, obese people often face prejudice or discrimination in the job market, at school, and in social situations. Feelings of rejection, shame, or depression are common. Since the 1950s, national dietary recommendations have come to acknowledge obesity as a significant societal trend. The Surgeon General's 2001 Call To Action, Healthy People 2010, and the Dietary Guidelines for Americans 2000 all emphasize the importance of healthy weight. There are some new tools available to help in the fight against overweight and obesity: Weight Control Information Network, The Third National Cholesterol Education Program's Adult Treatment Panel, and The Practical Guide: Identification, Evaluation, & Treatment of Overweight & Obesity in Adults from the National Institutes of Health and National Heart Lung and Blood Institute. AN - WOS:000180908100009 AU - Wellman, N. S. AU - Friedberg, B. DO - 10.1046/j.1440-6047.11.s8.6.x N1 - Wellman, NS Friedberg, B Symposium on Forging Effective Strategies for Prevention and Management of Overweight and Obesity in Asia: Research Education and Partnerships Apr 22-24, 2002 Singapore FENTON, MIRIAM C/B-6430-2011; Robles-Sardin, Alma E/M-7714-2015 Robles-Sardin, Alma E/0000-0003-2044-7793 1440-6047 PY - 2002 SN - 0964-7058 SP - S705-S709 ST - Causes and consequences of adult obesity: health, social and economic impacts in the United States T2 - Asia Pacific Journal of Clinical Nutrition TI - Causes and consequences of adult obesity: health, social and economic impacts in the United States UR - ://WOS:000180908100009 VL - 11 ID - 2838 ER - TY - JOUR AB - Our objective was to determine patterns, reasons for, and correlates of complementary and alternative medicine (CAM) use in US adults with common neurological conditions. We compared CAM use between adults with and without common neurological conditions (regular headaches, migraines, back pain with sciatica, strokes, dementia, seizures, or memory loss) using the 2007 National Health Interview Survey of 23,393 sampled US adults. Adults with common neurological conditions used CAM more frequently than those without (44.1 vs. 32.6%, p < 0.0001); differences persisted after adjustment. For each CAM modality, adults with common neurological conditions were more likely to use CAM than those without these conditions. Nearly half of adults with back pain with sciatica, memory loss, and migraines reported use of CAM. Mind/body therapies were used the most; alternative medical systems were used the least. Over 50% of adults with common neurological conditions who used CAM had not discussed their use with their health care provider. Those with neurological conditions used CAM more often than those without because of provider recommendation, or because conventional treatments were perceived ineffective or too costly. Significant correlates of CAM use among adults with common neurological conditions include higher than high school education, anxiety in the prior year, living in the west, being a former smoker, and light alcohol use. CAM is used more frequently among adults with common neurological conditions than those without. More research on the efficacy of CAM use for common neurological conditions is warranted. AD - Division for Research and Education in Complementary and Integrative Medical Therapies, Osher Research Center, Harvard Medical School, Landmark Center, Suite 22A-West, Boston, MA 02215, USA. Rebecca_Wells@hms.harvard.edu AN - 20535493 AU - Wells, R. E. AU - Phillips, R. S. AU - Schachter, S. C. AU - McCarthy, E. P. C2 - PMC3050588 C6 - NIHMS260102 DA - Nov DO - 10.1007/s00415-010-5616-2 DP - NLM ET - 2010/06/11 IS - 11 KW - Adolescent Adult Age Distribution Aged Complementary Therapies/*statistics & numerical data Female Humans Male Middle Aged Nervous System Diseases/*therapy United States Young Adult LA - eng N1 - 1432-1459 Wells, Rebecca Erwin Phillips, Russell S Schachter, Steven C McCarthy, Ellen P K24AT000589/AT/NCCIH NIH HHS/United States R03AT002236/AT/NCCIH NIH HHS/United States T32 AT000051/AT/NCCIH NIH HHS/United States K24 AT000589/AT/NCCIH NIH HHS/United States R03 AT002236/AT/NCCIH NIH HHS/United States T32AT000051/AT/NCCIH NIH HHS/United States K23 AT008406/AT/NCCIH NIH HHS/United States Journal Article Research Support, N.I.H., Extramural J Neurol. 2010 Nov;257(11):1822-31. doi: 10.1007/s00415-010-5616-2. Epub 2010 Jun 11. PY - 2010 SN - 0340-5354 (Print) 0340-5354 SP - 1822-31 ST - Complementary and alternative medicine use among US adults with common neurological conditions T2 - J Neurol TI - Complementary and alternative medicine use among US adults with common neurological conditions VL - 257 ID - 4054 ER - TY - JOUR AB - AIM: The aim of this study was to investigate parent perspectives on how heritable disorders of connective tissue (HDCT) affect a child's everyday life. In addition, this study aimed to determine if parents seeking health professional services perceive their children with HDCT to have difficulties with activities reliant on hand function. METHODS: This cross-sectional study used a questionnaire for parents to explore the impact of an HDCT on a child's ability to carry out everyday activities. Parents of children (8-18 years) attending a tertiary connective tissue dysplasia clinic, over a 12-month period, were invited to participate. RESULTS: We analysed 100 surveys completed by parents. Children with Ehlers-Danlos syndrome-hypermobile type, joint hypermobility syndrome (48%) and osteogenesis imperfecta (42%) were the largest diagnostic groups represented. Pain (73%) and fatigue (68%) were the most common symptoms parents perceived to affect day-to-day activities. More parents were satisfied with their child's self-care (61%) than school participation (33%). Keeping up with handwriting (71%) and gross motor activities (70%) were the most frequently reported difficulties at school. Most parents (65%) reported leisure activity difficulties, with pain (64%) and fatigue (60%) as the main contributing factors. CONCLUSIONS: This study has provided new knowledge about the concerns of parents with their child's engagement in everyday life including the impact of HDCT on hand function. Further research is needed on effective management strategies to reduce symptoms and improve hand function for these children. AD - Faculty of Medicine and Health Sydney, The University of Sydney, Sydney, Australia. Occupational Therapy Department, The Children's Hospital at Westmead, Sydney, Australia. Institute of Diabetes and Endocrinology, The Children's Hospital at Westmead, Sydney, Australia. Department of Health Professions, Macquarie University, Sydney, Australia. AN - 33244831 AU - Wesley, A. AU - Bray, P. AU - Munns, C. F. AU - Pacey, V. DA - May DO - 10.1111/jpc.15284 DP - NLM ET - 2020/11/28 IS - 5 KW - Child Connective Tissue Cross-Sectional Studies *Ehlers-Danlos Syndrome Fatigue Humans Parents Surveys and Questionnaires allied health daily activity heritable disorder of connective tissue hypermobility parent perspective LA - eng N1 - 1440-1754 Wesley, Alison Orcid: 0000-0003-4801-9264 Bray, Paula Munns, Craig F Pacey, Verity Journal Article Australia J Paediatr Child Health. 2021 May;57(5):626-630. doi: 10.1111/jpc.15284. Epub 2020 Nov 26. PY - 2021 SN - 1034-4810 SP - 626-630 ST - Impact of heritable disorders of connective tissue on daily life of children: Parent perspectives T2 - J Paediatr Child Health TI - Impact of heritable disorders of connective tissue on daily life of children: Parent perspectives VL - 57 ID - 3967 ER - TY - JOUR AB - Background: Chronic pain and fatigue are both common complaints in childhood and adolescence and often persist over time. The aim of the study was to investigate whether chronic pain/fatigue persists during adulthood and how former patients function and participate in society as adults. Methods: This historical cohort study used questionnaires to gather the data. Predictors for social participation in adulthood were also identified. Differences in functioning and health care use between young adults with current pain/fatigue complaints and those without were also discussed. Results: Ninety-four young adults responded; their mean age was 26.6 years and 91.5% were women. The average time since treatment was 10.2 years. 63.4% reported ongoing or new pain/fatigue complaints. 72.0% had a paid job; of those who worked, 22.1% reported taking sick leave in the past month. 78.7% of them reported having one or more chronic diseases. A higher level of pain/fatigue measured pre-treatment was identified as a predictor for more impaired social participation in adulthood. Young adults with current pain/fatigue complaints reported more healthcare utilization, lower levels of physical functioning and limitations in daily activities due to physical problems. Conclusions: A considerable number of these young adults still have pain/fatigue complaints in adulthood. More pain/fatigue pre-treatment during adolescence predict impaired functioning in the work-educational domain in young adulthood. What does this study add?: This study examines the social participation of young adults who suffered from severe chronic pain/fatigue during adolescence. Predictors for social participation are reported, as are the differences between young adults with and without persistent pain/fatigue complaints. AN - WOS:000379839200009 AU - Westendorp, T. AU - Verbunt, J. A. AU - Remerie, S. C. AU - de Blecourt, A. C. E. AU - van Baalen, B. AU - Smeets, Rjem DA - Aug DO - 10.1002/ejp.836 IS - 7 N1 - Westendorp, T. Verbunt, J. A. Remerie, S. C. de Blecourt, A. C. E. van Baalen, B. Smeets, R. J. E. M. Smeets, Rob JEM/D-1522-2011 Smeets, Rob JEM/0000-0002-9503-366X 1532-2149 PY - 2016 SN - 1090-3801 SP - 1121-1130 ST - Social functioning in adulthood: Understanding long-term outcomes of adolescents with chronic pain/fatigue treated at inpatient rehabilitation programs T2 - European Journal of Pain TI - Social functioning in adulthood: Understanding long-term outcomes of adolescents with chronic pain/fatigue treated at inpatient rehabilitation programs UR - ://WOS:000379839200009 VL - 20 ID - 2155 ER - TY - JOUR AB - OBJECTIVE: To assess the value of colorectal physiological tests in patients with functional disorders of defecation. DESIGN: Prospective study. SETTING: Academic hospital. SUBJECTS: 308 consecutive patients. INTERVENTIONS: Routine history and physical examination, followed by colonic transit study, and manometry, cinedefecography, electromyography of the anal sphincter, and assessment of terminal motor latency of the pudendal nerve. MAIN OUTCOME MEASURES: Number of diagnoses made after physiological tests compared with routine history and examination alone. RESULTS: Definitive diagnoses were made after history and physical examination alone in 15/180 (8%) with constipation, 9/80 (11%) with incontinence, and 11/48 (23%) with intractable rectal pain. The figures after physiological tests were 135/180 (75%), 53/80 (66%), and 20/48 (42%), respectively. Among the diagnoses made by physiological testing alone were: in patients with constipation, paradoxical puborectalis contraction (n = 59), colonic inertia (n = 31), rectocele (n = 19), and intussusception (n = 18); in those with incontinence, loss of muscle fiber (n = 21), neuropathy (n = 10), and both (n = 15); and in those with rectal pain, neuropathy (n = 6) and paradoxical puborectalis contraction (n = 3). The numbers of patients that remained undiagnosed in the three groups were 45 (25%), 27 (34%), and 28 (58%), respectively. Treatable conditions were diagnosed by physiological testing in 120/180 patients with constipation (67%) and 44 patients with incontinence (55%). Only 9 patients with rectal pain had treatable causes identified by physiologic testing. CONCLUSION: The value of colorectal physiological tests is greatest in patients who present with constipation or incontinence; they are of little value in those with chronic intractable rectal pain. AD - Department of Colorectal Surgery, Cleveland Clinic Florida, Fort Lauderdale, Florida. AN - 8003569 AU - Wexner, S. D. AU - Jorge, J. M. DA - Mar DP - NLM ET - 1994/03/01 IS - 3 KW - Adolescent Adult Aged Aged, 80 and over Anal Canal/physiopathology Child Colon/*physiopathology Colonic Diseases, Functional/diagnosis/physiopathology Constipation/*diagnosis/physiopathology Electromyography Fecal Incontinence/*diagnosis/physiopathology Female Gastrointestinal Transit Humans Male Manometry Medical History Taking *Medical Laboratory Science Middle Aged Motion Pictures Pain, Intractable/diagnosis/physiopathology Physical Examination Prospective Studies Rectal Diseases/diagnosis/physiopathology Rectum/*physiopathology LA - eng N1 - Wexner, S D Jorge, J M Journal Article England Eur J Surg. 1994 Mar;160(3):167-74. PY - 1994 SN - 1102-4151 (Print) 1102-4151 SP - 167-74 ST - Colorectal physiological tests: use or abuse of technology? T2 - Eur J Surg TI - Colorectal physiological tests: use or abuse of technology? VL - 160 ID - 3506 ER - TY - JOUR AB - OBJECTIVE: Migraine affects approximately 4%-11% of elementary school children; yet reaching a diagnosis in this age group can be challenging. The goal of this study was to develop a screening migraine questionnaire that could be easily implemented by a general pediatrician and validate its use in diagnosing migraine in children 5-12 years old. METHODS: A questionnaire, the McMaster Migraine Tool, was developed using the International Classification of Headache Disorders-II criteria for migraine. The validity of the questionnaire was assessed by comparing the diagnosis based on the results of the questionnaire compared with the diagnosis made by a pediatric neurologist. RESULTS: The questionnaire was used to assess a cohort of 69 children referred to the Pediatric Neurology Clinic for headache. The sensitivity and specificity of the McMaster Migraine Tool were determined to be 84% and 69%, respectively. Families graded its ease of use to be 9 of 10 (10 being easy to use). CONCLUSION: The McMaster Migraine Tool may be useful in diagnosing migraine in 5-12-year-old children, as it is readily completed and regarded as easy to use. Application of this tool could lead to expedited diagnosis and management of migraine. AD - Division of Pediatric Neurology, Department of Pediatrics, McMaster Children's Hospital, McMaster University, Hamilton, Ontario, Canada. Electronic address: robyn.whitney@medportal.ca. Division of Pediatric Neurology, Department of Pediatrics, McMaster Children's Hospital, McMaster University, Hamilton, Ontario, Canada. Department of Pediatrics, McMaster Children's Hospital, McMaster University, Hamilton, Ontario, Canada. AN - 25693584 AU - Whitney, R. AU - Borys, O. AU - Callen, D. J. AU - Latchman, A. DA - Feb DO - 10.1016/j.pediatrneurol.2014.09.011 DP - NLM ET - 2015/02/20 IS - 2 KW - Child Child, Preschool Female Humans Male Migraine Disorders/*diagnosis Outcome Assessment, Health Care *Pediatrics Prospective Studies Sensitivity and Specificity *Surveys and Questionnaires children diagnosis migraine questionnaire sensitivity specificity validation LA - eng N1 - 1873-5150 Whitney, Robyn Borys, Oksana Callen, David J A Latchman, Andrew Journal Article Validation Study United States Pediatr Neurol. 2015 Feb;52(2):214-7.e7. doi: 10.1016/j.pediatrneurol.2014.09.011. Epub 2014 Sep 28. PY - 2015 SN - 0887-8994 SP - 214-7.e7 ST - The McMaster Pediatric Migraine Questionnaire: a prospective validation study T2 - Pediatr Neurol TI - The McMaster Pediatric Migraine Questionnaire: a prospective validation study VL - 52 ID - 3599 ER - TY - JOUR AB - Aim: The aim of this paper is to present an update of the Back School concept including recent randomised controlled Studies, systematic reviews and guidelines. Method: After definition and classification of the origins of the Back School concept, results Of randomised controlled studies and systematic reviews within the framework of the Cochrane Collaboration Back Review Group are presented with their consequences with regard to German and International guidelines for the rehabilitation and prevention of low-back pain. Results: The Back School, integrated into a multi-disciplinary programme, is effective in the rehabilitation and prevention of recurrent and chronic low-back pain. It is not effective for acute back problems when compared to other treatment modalities. There is moderate evidence suggesting that back schools in an occupational setting reduce pain and improve function and return to work status. Conclusion: The classic Structure of the Back School with information, back protection exercises and gymnastics can be practiced successfully for chronic low-back pain and in all occupational setting. Insurance companies should consider the low-cost technology. For children, adolescents and for older people with osteoporosis and lumbar spinal stenosis, a special age-orientated design of the Back School is necessary. AN - WOS:000265649600017 AU - Wiese, M. AU - Kramer, J. AU - Becker, C. AU - Nentwig, V. AU - Theodoridis, T. AU - Teske, W. DA - Mar-Apr DO - 10.1055/s-2008-1039234 IS - 2 N1 - Wiese, M. Kraemer, J. Becker, C. Nentwig, V. Theodoridis, T. Teske, W. 1864-6743 PY - 2009 SN - 1864-6697 SP - 194-198 ST - Back School - An Update T2 - Zeitschrift Fur Orthopadie Und Unfallchirurgie TI - Back School - An Update UR - ://WOS:000265649600017 VL - 147 ID - 2613 ER - TY - JOUR AB - Background: Negative trends in adolescent mental and subjective health are a challenge to public health work in Sweden and worldwide. Self-reported mental and subjective health complaints such as pain, sleeping problems, anxiety, and various stress-related problems seem to have increased over time among older adolescents, especially girls. The aim of this study has therefore been to investigate perceived stress, mental and subjective health complaints among older adolescents in Northern Sweden. Methods: Data were derived from a cross-sectional school-based survey with a sample consisting of 16-18 year olds (n = 1027), boys and girls, in the first two years of upper secondary school, from different vocational and academic programmes in three public upper secondary schools in a university town in northern Sweden. Prevalence of perceived stress, subjective health complaints, general self-rated health, anxiety, and depression were measured using a questionnaire, including the Hospital Anxiety and Depression Scale (HADS). Results: A large proportion of both girls and boys reported health complaints and perceived stress. There was a clear gender difference: two to three times as many girls as boys reported subjective health complaints, such as headache, tiredness and sleeping difficulties and musculoskeletal pain, as well as sadness and anxiety. High pressure and demands from school were experienced by 63.6% of girls and 38.5% of boys. Perceived stress in the form of pressure and demands correlated strongly with reported health complaints (r = 0.71) and anxiety (r = 0.71). Conclusions: The results indicate that mental and subjective health complaints are prevalent during adolescence, especially in girls, and furthermore, that perceived stress and demands may be important explanatory factors. Future studies should pay attention to the balance between gender-related demands, perceived control and social support, particularly in the school environment, in order to prevent negative strain and stress-related ill-health. The gender gap in subjective adolescent health needs to be further explored. AN - WOS:000313105400001 AU - Wiklund, M. AU - Malmgren-Olsson, E. B. AU - Ohman, A. AU - Bergstrom, E. AU - Fjellman-Wiklund, A. C7 - 993 DA - Nov DO - 10.1186/1471-2458-12-993 N1 - Wiklund, Maria Malmgren-Olsson, Eva-Britt Ohman, Ann Bergstrom, Erik Fjellman-Wiklund, Anncristine 1471-2458 PY - 2012 ST - Subjective health complaints in older adolescents are related to perceived stress, anxiety and gender - a cross-sectional school study in Northern Sweden T2 - Bmc Public Health TI - Subjective health complaints in older adolescents are related to perceived stress, anxiety and gender - a cross-sectional school study in Northern Sweden UR - ://WOS:000313105400001 VL - 12 ID - 2410 ER - TY - JOUR AU - Williams, N. AU - Jackson, D. AU - Lambert, P. C. AU - Johnstone, J. M. DA - 1999/05/29/ DP - PubMed IS - 7196 J2 - BMJ KW - Abdominal Pain Adolescent Appendicitis Child Child, Preschool England Hospitalization Humans Incidence School Health Services Time Factors LA - eng PY - 1999 SN - 0959-8138 SP - 1455 ST - Incidence of non-specific abdominal pain in children during school term T2 - BMJ (Clinical research ed.) TI - Incidence of non-specific abdominal pain in children during school term: population survey based on discharge diagnoses UR - http://www.ncbi.nlm.nih.gov/pubmed/10346771 VL - 318 ID - 120 ER - TY - JOUR AB - Objectives: Obesity is associated with functional disability in adults with chronic pain, but less is known about obesity among youth with chronic pain. The purpose of this study was to (1) identify the prevalence of overweight and obesity in children and adolescents receiving treatment for chronic pain, and (2) examine associations between Body Mass Index (BMI), pain intensity, and activity limitations in this population. Methods: Data were obtained from records of 118 patients, ages 8 to 18, seen in a multidisciplinary pediatric pain clinic. Information about age, sex, pain problem, duration and severity, medical diagnoses, medications, height, and weight were collected from medical records and intake questionnaires. The CDC's pediatric BMI calculator was used to obtain percentile and category (underweight, healthy weight, overweight, obese). Children and parents completed the Child Activity Limitations Interview-21 (CALI-21), a self-report measure of activity limitations. Results: A significantly higher rate of overweight and obesity was observed among youth with chronic pain compared with a normative sample. BMI percentile was predictive of concurrent limitations in vigorous activities, according to parent report. Discussion: BMI percentile and weight status may contribute to activity limitations among children and adolescents with chronic pain. Weight status is an important factor to consider in the context of treatment of chronic pain and disability in children and adolescents. AN - WOS:000281818200009 AU - Wilson, A. C. AU - Samuelson, B. AU - Palermo, T. M. DA - Oct IS - 8 N1 - Wilson, Anna C. Samuelson, Bethany Palermo, Tonya M. Samuelson Bannow, Bethany/0000-0002-9981-8990 1536-5409 PY - 2010 SN - 0749-8047 SP - 705-711 ST - Obesity in Children and Adolescents With Chronic Pain: Associations With Pain and Activity Limitations T2 - Clinical Journal of Pain TI - Obesity in Children and Adolescents With Chronic Pain: Associations With Pain and Activity Limitations UR - ://WOS:000281818200009 VL - 26 ID - 2534 ER - TY - JOUR AB - In 1988 the International Headache Society presented new criteria for the diagnosis of migraine. We used these criteria in a questionnaire to assist in the diagnosis of migraine. The questionnaire was answered by 230 patients in four general practices. We found a migraine prevalence of 11.7%. More than 70% of migraine patients had 12 or more attacks per year, and the length of attack varied between 4 and 24 h in 80% of them. The majority of migraineurs went to bed during the attack and 55% had stayed away from work due to migraine during the last year. The results of this study are in agreement with others. Migraine is an appreciable economic concern due to frequent short absenteeism from work. AN - 1384985 AU - Winnem, J. DA - Oct DO - 10.1046/j.1468-2982.1992.1205300.x DP - NLM ET - 1992/10/01 IS - 5 KW - Absenteeism Adolescent Adult Aged *Family Practice Female Humans Male Middle Aged Migraine Disorders/*epidemiology/physiopathology/therapy Palliative Care Prevalence Surveys and Questionnaires Time Factors LA - eng N1 - Winnem, J Journal Article England Cephalalgia. 1992 Oct;12(5):300-3. doi: 10.1046/j.1468-2982.1992.1205300.x. PY - 1992 SN - 0333-1024 (Print) 0333-1024 SP - 300-3 ST - Prevalence of adult migraine in general practice T2 - Cephalalgia TI - Prevalence of adult migraine in general practice VL - 12 ID - 3457 ER - TY - JOUR AB - A 7-year-old boy presented with a 4-week history of daily headache. His parents reported that he was unable to attend school the week prior to presentation. Intermittent nausea without vomiting was reported, but no blurred vision, photophobia, or diplopia were described. There was no history of trauma or recent systemic illness. The physical examination showed mild neck discomfort, no papilledema, and normal cranial nerve, motor and sensory functioning. Both a CT scan of the sinuses and an MRI of the brain were normal. Although the opening pressure was elevated, the cerebrospinal fluid was also normal. In previous accounts of idiopathic intracranial hypertension in children, concomitant papilledema, visual symptoms and/or palsy of the sixth cranial nerve are described. This case demonstrates that idiopathic intracranial hypertension in a young child can present as a daily headache without any visual symptoms or signs. AD - Palm Beach Headache Center, West Palm Beach, Fla. 33407, USA. AN - 8916568 AU - Winner, P. AU - Bello, L. DA - Oct DO - 10.1046/j.1526-4610.1996.3609574.x DP - NLM ET - 1996/10/01 IS - 9 KW - Acetazolamide/therapeutic use Carbonic Anhydrase Inhibitors/therapeutic use Child Headache/drug therapy/*etiology/physiopathology Humans Intracranial Pressure Male Pseudotumor Cerebri/*complications/drug therapy/physiopathology Vision Disorders/etiology LA - eng N1 - Winner, P Bello, L Case Reports Journal Article United States Headache. 1996 Oct;36(9):574-6. doi: 10.1046/j.1526-4610.1996.3609574.x. PY - 1996 SN - 0017-8748 (Print) 0017-8748 SP - 574-6 ST - Idiopathic intracranial hypertension in a young child without visual symptoms or signs T2 - Headache TI - Idiopathic intracranial hypertension in a young child without visual symptoms or signs VL - 36 ID - 4104 ER - TY - JOUR AB - AIM: To evaluate the contribution of certain parafunctional activities to the presence of temporomandibular disorder (TMD) symptoms among teenage girls, with special emphasis to gum chewing and jaw play. METHODS: A total of 323 girls, aged 15-16 years, were randomly selected from a religious junior high school. The girls responded to a questionnaire on oral habits and TMD symptoms. RESULTS: Gum chewing was a very prevalent habit (62.4%), performed daily (mean chewing time 3.95 h day-1). Girls who chewed intensively (more than 4 h day-1) showed associations with pain in the ear area during function and at rest, as well as with joint noises. Jaw play, although reported by only 14.3%, was significantly associated with pain in the ear area during function and at rest, feeling of tiredness of the jaw while chewing, joint noises, catch and lock. All oral parafunctions, except chewing gum, were associated with jaw play and with each other. CONCLUSIONS: Jaw play was the most detrimental habit in TMD; intensive gum chewing was a potentially contributing factor for joint noises and pain. Oral parafunctions (except chewing gum) were significantly associated between themselves and suggest a behavioural pattern of "jaw hyperactivity". AD - Department of Occlusion and Behavioral Sciences, The Maurice and Gabriela Goldschleger School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel. AN - 11422693 AU - Winocur, E. AU - Gavish, A. AU - Finkelshtein, T. AU - Halachmi, M. AU - Gazit, E. DA - Jul DO - 10.1046/j.1365-2842.2001.00708.x DP - NLM ET - 2001/06/26 IS - 7 KW - Adolescent *Adolescent Behavior Bruxism/complications Chewing Gum/*adverse effects Chi-Square Distribution Feeding Behavior Female Habits Humans Mandible/physiology Mastication Movement Statistics, Nonparametric Surveys and Questionnaires Temporomandibular Joint Dysfunction Syndrome/*etiology/psychology LA - eng N1 - Winocur, E Gavish, A Finkelshtein, T Halachmi, M Gazit, E Journal Article England J Oral Rehabil. 2001 Jul;28(7):624-9. doi: 10.1046/j.1365-2842.2001.00708.x. PY - 2001 SN - 0305-182X (Print) 0305-182x SP - 624-9 ST - Oral habits among adolescent girls and their association with symptoms of temporomandibular disorders T2 - J Oral Rehabil TI - Oral habits among adolescent girls and their association with symptoms of temporomandibular disorders VL - 28 ID - 3612 ER - TY - JOUR AB - Background: Although adolescent spinal pain increases the risk for chronic back pain in adulthood, most adolescents can be regarded as healthy. The aim of the present study was to provide data on localization, intensity and frequency of adolescent spinal pain and to investigate which physical and psycho-social parameters predict these pain characteristics. Method: On the occasion of Spine Day, an annual event where children and adolescents are examined by chiropractors on a voluntary basis for back problems, 412 adolescents (10 to 16 years) were tested (by questionnaire and physical examination). Pain characteristics (localization, intensity, and frequency) were identified and evaluated using descriptive statistics. Regression analyses were performed to investigate possible influencing psycho-social and physical influence factors. Results: Adolescents who suffered from pain in more than one spinal area reported higher pain intensity and frequency than those with pain in only one spinal area. Sleep disorders were a significant predictor for pain in more than one spinal area (p < 0.01) as well as a trend for frequent pain (p = 0.06). Adolescents with frequent pain showed impaired balance on one leg standing with closed eyes (p = 0.02). Conclusions: Studies on adolescent spinal pain should report data on pain frequency, intensity and localization. Adolescents who present with pain in more than one spinal area or report frequent pain should be followed carefully. Reduced balance with visual deprivation might be a physical indicator of a serious back problem. AN - WOS:000353439300001 AU - Wirth, B. AU - Humphreys, B. K. C7 - 42 DA - Apr DO - 10.1186/s12887-015-0344-5 N1 - Wirth, Brigitte Humphreys, B. Kim PY - 2015 SN - 1471-2431 ST - Pain characteristics of adolescent spinal pain T2 - Bmc Pediatrics TI - Pain characteristics of adolescent spinal pain UR - ://WOS:000353439300001 VL - 15 ID - 2239 ER - TY - JOUR AB - BACKGROUND: The key to a better understanding of the immense problem of spinal pain seems to be to investigate its development in adolescents. Based on the data of Spine Day 2012 (an annual action day where Swiss school children were examined by chiropractors on a voluntary basis for back problems), the aim of the present study was to gain systematic epidemiologic data on adolescent spinal pain in Switzerland and to explore risk factors per gender and per spinal area. METHOD: Data (questionnaires and physical examinations) of 836 school children were descriptively analyzed for prevalence, recurrence and severity of spinal pain. Of those, 434 data sets were included in risk factor analysis. Using logistic regression analysis, psycho-social parameters (presence of parental back pain, parental smoking, media consumption, type of school bag) and physical parameters (trunk symmetry, posture, mobility, coordination, BMI) were analyzed per gender and per spinal area. RESULTS: Prevalence of spinal pain was higher for female gender in all areas apart from the neck. With age, a steep increase in prevalence was observed for low back pain (LBP) and for multiple pain sites. The increasing impact of spinal pain on quality of life with age was reflected in an increase in recurrence, but not in severity of spinal pain. Besides age and gender, parental back pain (Odds ratio (OR)=3.26, p=0.011) and trunk asymmetry (OR=3.36, p=0.027) emerged as risk factors for spinal pain in girls. Parental smoking seemed to increase the risk for both genders (boys: OR=2.39, p=0.020; girls: OR=2.19, p=0.051). Risk factor analysis per spinal area resulted in trunk asymmetry as risk factor for LBP (OR=3.15, p=0.015), while parental smoking increased the risk for thoracic spinal pain (TSP) (OR=2.83, p=0.036) and neck pain (OR=2.23, p=0.038). The risk for TSP was further enhanced by a higher BMI (OR=1.15, p=0.027). CONCLUSION: This study supports the view of adolescent spinal pain as a bio-psycho-social problem that should be investigated per spinal area, age and gender. The role of trunk asymmetry and passive smoking as risk factors as well as the association between BMI and TSP should be further investigated, preferably in prospective studies. AU - Wirth, Brigitte AU - Knecht, Christina AU - Humphreys, Kim DA - 2013/10/05/ DO - 10.1186/1471-2431-13-159 DP - PubMed J2 - BMC Pediatr KW - Adolescent Back Pain Body Mass Index Child Chiropractic Female Humans Male Pain Measurement Physical Examination Prevalence Risk Factors Sex Factors Surveys and Questionnaires Switzerland Tobacco Smoke Pollution LA - eng PY - 2013 SN - 1471-2431 SP - 159 ST - Spine Day 2012 T2 - BMC pediatrics TI - Spine Day 2012: spinal pain in Swiss school children- epidemiology and risk factors UR - http://www.ncbi.nlm.nih.gov/pubmed/24094041 VL - 13 ID - 89 ER - TY - JOUR AB - Background: The aim of the study was to identify familial and community environmental risk factors associated with Helicobacter pylori infection in a pediatric population. Methods: Children requiring diagnostic upper endoscopy were included in the study during a 2-year period. During endoscopy, five gastric biopsies were per-formed for the histologic or bacteriologic diagnosis, or both, of H. pylori infection. Epidemiologic data collected by a questionnaire were analyzed using the chi-square test or Fisher test and stepwise logistic regression. Results: The authors included 436 patients (242 boys), aged 2 days to 17.9 years (median, 2.7 years). H. pylori prevalence was 7.3%. Univariate analysis found H. pylori was more common in older patients (P < 0.00001), in children who had at least one parent born in a developing country (P < 0.02) or with a low socioeconomic status (P < 0.02), and in those living in crowded conditions (P < 0.02). Children whose mother worked at home were more frequently infected than children whose mother worked outside the home (P < 0.02). Attendance at nursery or school before the age of 6 years was not associated with infection. Logistic regression showed a strong association with H. pylori only for age and number of persons at home. Conclusions: The Source of H. pylori is intrafamilial rather than from a community, such as nursery and school attended at a young age. The number of persons in the home influences the infection status of children but not by the presence of the mother in home. These data suggest that H. pylori infection transmission occurs from siblings or the father rather than from mother. AN - WOS:000170145800010 AU - Wizla-Derambure, N. AU - Michaud, L. AU - Ategbo, S. AU - Vincent, P. AU - Ganga-Zandzou, S. AU - Turck, D. AU - Gottrand, F. DA - Jul DO - 10.1097/00005176-200107000-00010 IS - 1 N1 - Wizla-Derambure, N Michaud, L Ategbo, S Vincent, P Ganga-Zandzou, S Turck, D Gottrand, F gottrand, frederic F/G-7370-2015; Michaud, Laurent/S-2041-2018; Turck, Dominique/S-2382-2018 gottrand, frederic F/0000-0002-5290-0436; Michaud, Laurent/0000-0002-5020-1367; Turck, Dominique/0000-0003-1370-4667 PY - 2001 SN - 0277-2116 SP - 58-63 ST - Familial and community environmental risk factors for Helicobacter pylori infection in children and adolescents T2 - Journal of Pediatric Gastroenterology and Nutrition TI - Familial and community environmental risk factors for Helicobacter pylori infection in children and adolescents UR - ://WOS:000170145800010 VL - 33 ID - 2848 ER - TY - JOUR AB - BACKGROUND: Headache is a leading disabler in adults worldwide. In children and adolescents, the same may be true but the evidence is much poorer. It is notable that published epidemiological studies of these age groups have largely ignored headaches not fulfilling any specific set of ICHD criteria, although such headaches appear to be common. A new approach to these is needed: here we introduce, and investigate, a diagnostic category termed "undifferentiated headache" (UdH), defined in young people as recurrent mild-intensity headache of < 1 h's duration. METHODS: We conducted a nationwide cross-sectional survey in 31 schools in six regions of Turkey selected by mixed convenience-based and purposive modified cluster-sampling. A validated, standardised self-completed structured questionnaire was administered by a physician-investigator to entire classes of pupils aged 6-17 years. RESULTS: Of the identified sample of 7889 pupils, 7088 (89.8%) participated. The 1-year prevalence of UdH was 29.2%, of migraine (definite and probable) 26.7%, and of tension-type headache (TTH) (definite and probable) 12.9%. UdH differed with respect to almost all headache features and associated symptoms from both migraine and TTH. Burden of headache and use of acute medication were lower in UdH than in migraine and TTH. Headache yesterday was less common in UdH than migraine (OR 0.32; 95% CI 0.28-0.37) and TTH (OR 0.64; 95% CI 0.56-0.77). Quality of life (QoL) was better in UdH (33.6 ± 5.2) than in migraine (30.3 ± 5.6; p < 0.001) and TTH (32.4 ± 5.3; p < 0.001), but worse than in pupils without headache (35.7 ± 4.7; p < 0.001). CONCLUSIONS: This large nationwide study in Turkey of pupils aged 6-17 years has shown that many children and adolescents have a headache type that does not conform to existing accepted diagnostic criteria. This new diagnostic category of presumably still-evolving headache (undifferentiated headache) is common. UdH differs in almost all measurable respects from both migraine and TTH. Although characterised by mild headaches lasting < 1 h, UdH is associated with significant adverse impact on QoL. Longitudinal cohort studies are needed to evaluate the prognosis of UdH but, meanwhile, recognition of UdH and its distinction from migraine and TTH has implications for epidemiological studies, public-health policy and routine clinical practice. AU - Wöber, Christian AU - Wöber-Bingöl, Çiçek AU - Uluduz, Derya AU - Aslan, Tuna Stefan AU - Uygunoglu, Uğur AU - Tüfekçi, Ahmet AU - Alp, Selen Ilhan AU - Duman, Taşkın AU - Sürgün, Fidan AU - Emir, Gülser Karadaban AU - Demir, Caner Feyzi AU - Balgetir, Ferhat AU - Özdemir, Yeliz Bahar AU - Auer, Tanja AU - Siva, Aksel AU - Steiner, Timothy J. DA - 2018/02/27/ DO - 10.1186/s10194-018-0847-1 DP - PubMed IS - 1 J2 - J Headache Pain KW - Adolescent Adolescents Burden of headache Child Children Cross-Sectional Studies Female Global Campaign against Headache Headache Headache yesterday Humans Longitudinal Studies Male Migraine Nationwide Population-based study Prevalence Quality of life Schools Surveys and Questionnaires Tension-type headache Turkey Undifferentiated headache LA - eng PY - 2018 SN - 1129-2377 SP - 18 ST - Undifferentiated headache T2 - The Journal of Headache and Pain TI - Undifferentiated headache: broadening the approach to headache in children and adolescents, with supporting evidence from a nationwide school-based cross-sectional survey in Turkey UR - http://www.ncbi.nlm.nih.gov/pubmed/29484508 VL - 19 ID - 52 ER - TY - JOUR AB - [Purpose] Spine disorders affect various sections of the spine and have a variety of causes. Most pain occurs in the lumbo-sacral and cervical regions. Dance is associated with exercise. High levels of physical activity predispose to back pain occurrence. [Subjects and Methods] The subjects were 237 ballet learners; 80 children (primary school level), mean age 11.24±0.77, mean of years of training ballet 2.14±0.74; 93 students (junior high school level), mean age 14.01±0.84, mean of years of learning ballet 4.64±1.24; 64 students (high school) mean age 17.01±0.77, mean of years of learning ballet 7.47±1.54. Numeric rating scale was used to determine spine pain. [Results] Feelings of pain were analyzed on the basis of "now" and "before" between levels education by using point statistics and statistical tests to compare groups. "Now" exhibited weaker back pain feelings than "before" at all the education levels. There were statistically significant differences in pain feeling for "before" (at any time of learning) and "now" (the day of survey). [Conclusion] All patients reported pain "before" and "now" in cervical, thoracic and lumbar spine. At all levels of education there were statistically significant differences in feelings of pain between "before" and "now". AU - Wójcik, Małgorzata AU - Siatkowski, Idzi DA - 2015/04// DO - 10.1589/jpts.27.1103 DP - PubMed IS - 4 J2 - J Phys Ther Sci KW - Back pain Ballet LA - eng PY - 2015 SN - 0915-5287 SP - 1103-1106 ST - Assessment of spine pain presence in children and young persons studying in ballet schools T2 - Journal of Physical Therapy Science TI - Assessment of spine pain presence in children and young persons studying in ballet schools UR - http://www.ncbi.nlm.nih.gov/pubmed/25995566 VL - 27 ID - 82 ER - TY - JOUR AB - OBJECTIVE: Fibromyalgia (FM) is a controversial construct. Recently suggested survey criteria identify persons with FM characteristics without physical examination or clinical diagnosis, thereby obviating many of the objections to FM. Little is known about FM among patients with rheumatoid arthritis (RAF). We used the survey definition to characterize persons with RAF and to obtain insight into possible pathogenic mechanisms. METHODS: A total of 11,866 patients with RA completed the Regional Pain Scale (RPS) and a 0-10 visual analog scale (VAS) for fatigue. FM was diagnosed in patients with an RPS score > or = 8 and a VAS fatigue score > or = 6. RESULTS: Altogether 1731 (17.1%) patients with RA fulfilled the criteria. Fewer RAF patients were married (64.9% vs 69.8%) and more were divorced (14.8% vs 10.4%); fewer were college graduates (19.7% vs 28.1%) and more did not finish high school (15.0% vs 8.9%). We found 35.8% of patients with FM but only 21.5% of those without FM had incomes less than 185% of the US poverty guidelines. Patients with RAF had higher validated hospitalization rates for major comorbid conditions and received treatment for comorbid conditions more often (expressed as odds ratios and 95% confidence interval): hypertension (1.5, 1.4-1.7), cardiovascular (1.8, 1.6-2.0), diabetes (1.9, 1.6-2.3), and depression (2.7, 1.8-4.2). RAF were 3.3 (3.0-3.7) times more likely to have been work-disabled (54.5% vs 26.4%) or to have total joint replacement (14.0% vs 11.2%; OR 1.3, 1.1-1.5), and incurred greater direct 6-month medical costs (6477 vs 4687 US dollars). RAF patients had more severe symptoms across all scales, including the Health Assessment Questionnaire (1.8 vs 1.0), pain (6.7 vs 3.4), Medical Outcomes Study Short Form-36 (SF-36) physical component score (23.5 vs 33.5), SF-36 mental component score (29.5 vs 46.1), and quality of life assessed by EuroQol mapped utilities (0.33 vs 0.65). CONCLUSION: FM exists in a substantial number of patients with RA (17.1%), who have more severe RA by subjective and objective measures, greater medical costs, worse outcomes, more comorbidities, sociodemographic disadvantage, and substantially worse quality of life. We hypothesize that illness severity and sociodemographic disadvantage both play a role in producing the clinical picture of FM. AD - National Data Bank for Rheumatic Diseases, Arthritis Research Center Foundation, University of Kansas School of Medicine, Wichita, Kansas 67214, USA. fwolfe@arthritis-research.org AN - 15088293 AU - Wolfe, F. AU - Michaud, K. DA - Apr DP - NLM ET - 2004/04/17 IS - 4 KW - Arthritis, Rheumatoid/epidemiology/etiology/*physiopathology Comorbidity Demography Disability Evaluation Fatigue/physiopathology Female Fibromyalgia/epidemiology/etiology/*physiopathology Health Status Humans Male Middle Aged Pain/physiopathology Pain Measurement Quality of Life Severity of Illness Index *Socioeconomic Factors Surveys and Questionnaires United States LA - eng N1 - Wolfe, Frederick Michaud, Kaleb Journal Article Research Support, Non-U.S. Gov't Canada J Rheumatol. 2004 Apr;31(4):695-700. PY - 2004 SN - 0315-162X (Print) 0315-162x SP - 695-700 ST - Severe rheumatoid arthritis (RA), worse outcomes, comorbid illness, and sociodemographic disadvantage characterize ra patients with fibromyalgia T2 - J Rheumatol TI - Severe rheumatoid arthritis (RA), worse outcomes, comorbid illness, and sociodemographic disadvantage characterize ra patients with fibromyalgia VL - 31 ID - 3587 ER - TY - JOUR AB - Objective The aim was to investigate the concurrent and longitudinal associations of chronic pain with behavioral and emotional problems in toddlers, as it is not known which comes first in life. Methods The study was embedded in the Generation R Study, a prospective population-based cohort study. Parents of 3,751 toddlers completed questionnaires of their child's health and development. Behavioral and emotional problems were measured at 1.5 and 3 years, chronic pain was measured at 2 and 3 years. Results There were concurrent associations between chronic pain and internalizing problems, e.g. anxiety/depression symptoms. However, chronic pain did not precede the development of new behavioral and emotional problems. Also, behavioral and emotional problems did not precede new-onset chronic pain, except for somatic symptoms, which increased the likelihood of chronic pain. Conclusions Chronic pain was associated with concurrent internalizing problems. Somatic complaints were not only concurrently related to pain but also predicted new-onset pain. AN - WOS:000304540900012 AU - Wolff, N. J. AU - Darlington, A. S. E. AU - Hunfeld, J. A. M. AU - Jaddoe, V. W. V. AU - Hofman, A. AU - Raat, H. AU - Verhulst, F. C. AU - Passchier, J. AU - Tiemeier, H. DA - Jun DO - 10.1093/jpepsy/jsr122 IS - 5 N1 - Wolff, Noor J. Darlington, Anne-Sophie E. Hunfeld, Joke A. M. Jaddoe, Vincent W. V. Hofman, Albert Raat, Hein Verhulst, Frank C. Passchier, Jan Tiemeier, Henning Tiemeier, Henning/H-6534-2019 Tiemeier, Henning/0000-0002-4395-1397; Darlington, Anne-Sophie/0000-0003-4387-7278 PY - 2012 SN - 0146-8693 SP - 546-556 ST - Concurrent and Longitudinal Bidirectional Relationships Between Toddlers' Chronic Pain and Mental Health: The Generation R Study T2 - Journal of Pediatric Psychology TI - Concurrent and Longitudinal Bidirectional Relationships Between Toddlers' Chronic Pain and Mental Health: The Generation R Study UR - ://WOS:000304540900012 VL - 37 ID - 2432 ER - TY - JOUR AB - There is evidence in humans and animals that neonatal and early infant pain and stress may sensitize excitatory pain pathways. Possibly such experiences may result in long-term diminished activation of phasic endogenous pain inhibitory mechanisms. We studied stress-induced activation of endogenous pain inhibitory mechanisms in school-aged children (10-16 years) who had suffered moderate (N= =12) or severe (N=10) burn injuries in infancy (6-24 months of age) and 20 controls. Before and after the stress phase, pain threshold and pain tolerance (heat, pressure, ischemic pain) were assessed. Stress was successfully induced in all children as reflected by increases in heart rate, blood pressure and perceived stress. In the controls, there was evidence for stress-induced hypoalgesia as reflected by significant increases in heat pain threshold, heat pain tolerance and pressure pain tolerance. Pressure pain thresholds were not significantly altered. A similar pattern was observed in the moderately burned children. By contrast, children with severe burn injuries failed to show significant stress-related changes in heat and pressure pain sensitivity. In all groups, ischemic pain sensitivity was elevated post stress. The children reported being more distressed by the perceived loss of strength than by pain and had difficulties differentiating between the two. It is possible that ischemic pain may be less suitable for measuring pain sensitivity in children. The present study provides first evidence that pain and stress exposure due to severe burns in infancy may be associated with an attenuated stress-induced activation of phasic endogenous pain inhibitory mechanisms later in childhood and adolescence. AU - Wollgarten-Hadamek, Iris AU - Hohmeister, Johanna AU - Zohsel, Katrin AU - Flor, Herta AU - Hermann, Christiane DA - 2011/04// DO - 10.1016/j.ejpain.2010.09.001 DP - PubMed IS - 4 J2 - Eur J Pain KW - Adolescent Anticipation, Psychological Blood Pressure Burns Child Electrocardiography Female Heart Rate Hot Temperature Humans Infant Ischemia Male Pain Pain Measurement Pain Threshold Paternal Age Pressure Speech Stress, Psychological Surveys and Questionnaires LA - eng PY - 2011 SN - 1532-2149 SP - 423.e1-10 ST - Do school-aged children with burn injuries during infancy show stress-induced activation of pain inhibitory mechanisms? T2 - European Journal of Pain (London, England) TI - Do school-aged children with burn injuries during infancy show stress-induced activation of pain inhibitory mechanisms? UR - http://www.ncbi.nlm.nih.gov/pubmed/20934358 VL - 15 ID - 104 ER - TY - JOUR AB - INTRODUCTION: Placebo effects can be very effective in certain pain conditions, but their use is still highly controversial. Several studies show that patients would accept a placebo treatment under certain circumstances, particularly when they are informed prior to the treatment or when there are no effective treatment alternatives. This study examines the question, which factors influence the degree of acceptability of a hypothetical placebo application. METHODS: Patients filled in a questionnaire dealing with placebo applications. Moreover general data, diagnosis, duration of pain, pain ratings and anxiety/depression/stress scores, sleep disorders and opioid intake were collected from the patients` charts. 129 patients (44 men / 85 women, mean age 51.5 years, 18.0-80.9 years) entered the study. All patients had chronic pain syndromes and were treated in an universitary academic interdisciplinary pain center. Mean duration of pain was 14.7 years. RESULTS: The study did not show significant differences in placebo acceptability among patients with different pain diagnoses or accompanying psychological diagnoses or disorders. Hidden placebo application was considered much more unacceptable for the patients than the enhanced placebo or the open placebo application. An improved condition was associated with less feeling of deception, more trust and less negative mood than an unchanged or worsened condition. CONCLUSION: Acceptance of placebo as pain therapy is much more dependent on the way of application (hidden or open) or on the resulting condition (improved, unchanged or worsened) than on factors inherent in the individual patients. AD - University Hospital Freiburg, Interdisciplinary Pain Centre, Freiburg, Germany. AN - 30399194 AU - Wolter, T. AU - Kleinmann, B. C2 - PMC6219799 DO - 10.1371/journal.pone.0206968 DP - NLM ET - 2018/11/07 IS - 11 KW - Adolescent Adult Aged Aged, 80 and over Chronic Pain/*therapy Deception Female Humans Male Middle Aged Pain Management/*statistics & numerical data *Patient Acceptance of Health Care *Placebo Effect Surveys and Questionnaires Trust Young Adult LA - eng N1 - 1932-6203 Wolter, Tilman Orcid: 0000-0001-8184-3381 Kleinmann, Barbara Journal Article PLoS One. 2018 Nov 6;13(11):e0206968. doi: 10.1371/journal.pone.0206968. eCollection 2018. PY - 2018 SN - 1932-6203 SP - e0206968 ST - Placebo acceptability in chronic pain patients: More dependent on application mode and resulting condition than on individual factors T2 - PLoS One TI - Placebo acceptability in chronic pain patients: More dependent on application mode and resulting condition than on individual factors VL - 13 ID - 3172 ER - TY - JOUR AB - Background: Primary dysmenorrhoea is common in girls who have begun menstruating. However few studies have examined its effect on the quality of life of a young population. The study aimed to evaluate the quality of life of adolescent girls with dysmenorrhoea in Hong Kong. Methods: The study adopted a cross-sectional descriptive approach. A convenience sample of 653 girls aged 13 to 19 years old was recruited from three secondary schools in Hong Kong. The 36-item Short-Form Health Survey was used to examine the health-related quality of life of the participants. The severity of dysmenorrhoea was assessed using a 10 point visual analog scale. Results: Girls suffering from dysmenorrhoea reported high pain prevalence and intensity. However the majority of girls with dysmenorrhoea did not seek medical advice (93.2%) or self-medicate (82%). The role-physical bodily pain general health and social functioning domain scores of girls with dysmenorrhoea were significantly lower than those without dysmenorrhoea. Moreover girls with severe dysmenorrhoea had a significantly lower quality of life in the bodily pain domain than those with mild and moderate forms of condition. Conclusions: Findings suggest that dysmenorrhoea is highly prevalent among adolescent girls in Hong Kong. Girls may suffer severe pain which degrades their quality of life. AN - WOS:000432812300001 AU - Wong, C. L. C7 - 80 DA - May DO - 10.1186/s12978-018-0540-5 N1 - Wong, Cho Lee Wong, Cho Lee/A-4612-2015 Wong, Cho Lee/0000-0001-6640-1323 PY - 2018 SN - 1742-4755 ST - Health-related quality of life among Chinese adolescent girls with Dysmenorrhoea T2 - Reproductive Health TI - Health-related quality of life among Chinese adolescent girls with Dysmenorrhoea UR - ://WOS:000432812300001 VL - 15 ID - 2016 ER - TY - JOUR AB - Objective, To evaluate aspects of reliability and validity of the Juvenile Arthritis Functional Status Index (JASI). We developed this questionnaire to assess a variety of daily living and functional mobility tasks in children with juvenile rheumatoid arthritis (JRA). JASI Part I consists of 100 functional items divided into 5 activity categories (self-care, domestic, mobility, school, extracurricular). A 7 point degree of difficulty rating scale is used for responses. JASI Part II is a priority function section within which the child identifies and scores important activities for improvement. Methods, The JASI was administered to 30 children with JRA 8 to 19 years of age at baseline, 3 weeks, and 3 months to determine test-retest reliability. Various rheumatology measures were used to evaluate the JASI construct validity. Results, Reliability of JASI Part I was excellent (intraclass correlation coefficients greater than or equal to 0.95) for both retest intervals. Reliability was lower for respondents with mild disease than those with polyarticular disease. JASI Part I scores correlated strongly with rheumatology measures including joint count, grip strength, hip synovitis, timed walk and run, ACR functional class, and range of motion (r > 0.50), indicating construct validity. There was fair to good agreement between scores from the child's self-report and those from therapist observation of the child's abilities on the same activities. This provides evidence that children as young as 8 years of age can realistically report on function on their own. In JASI Part II, respondents identified a mean of 5.9 functional items in the baseline priority activity list, Test-retest reliability for JASI Part II was fair (kappa = 0.57). Further work is needed to determine the most reliable and sensitive response sequence for evaluating change in priority functions with JASI Part II. Conclusion, JASI Part I is a reliable and valid functional measure for school age children and adolescents with JRA. Research is under way to evaluate responsiveness to change. Comparisons will be made with shorter JRA functional measures to determine differences in sensitivity. AN - WOS:A1996UP53900022 AU - Wright, F. V. AU - Kimber, J. L. AU - Law, M. AU - Goldsmith, C. H. AU - Crombie, V. AU - Dent, P. DA - Jun IS - 6 N1 - Wright, FV Kimber, JL Law, M Goldsmith, CH Crombie, V Dent, P Wright, F Virginia/0000-0002-9713-4536 PY - 1996 SN - 0315-162X SP - 1066-1079 ST - The juvenile arthritis functional status index (JASI): A validation study T2 - Journal of Rheumatology TI - The juvenile arthritis functional status index (JASI): A validation study UR - ://WOS:A1996UP53900022 VL - 23 ID - 2928 ER - TY - JOUR AB - CONTEXT: Despite the growing popularity of qigong in the West, few well-controlled studies using a sham master to assess the clinical efficacy of qigong have been conducted. OBJECTIVE: To study the effect of qigong on treatment-resistant patients with late-stage complex regional pain syndrome type I. DESIGN: Block-random placebo-controlled clinical trial. SETTING: Pain Management Center at New Jersey Medical School. PATIENTS: 26 adult patients (aged 18 to 65 years) with complex regional pain syndrome type I. INTERVENTIONS: The experimental group received qi emission and qigong instruction (including home exercise) by a qigong master. The control group received a similar set of instructions by a sham master. The experimental protocol included 6 forty-minute qigong sessions over 3 weeks, with reevaluation at 6 and 10 weeks. Assessment included comprehensive medical history, physical exam, psychological evaluation, necessary diagnostic testing. Symptom Check List 90, and the Carleton University Responsiveness to Suggestion Scale. MAIN OUTCOME MEASURES: Thermography, swelling, discoloration, muscle wasting, range of motion, pain intensity rating, medication usage, behavior assessment (activity level and domestic disability), frequency of pain awakening, mood assessment, and anxiety assessment. RESULTS: 22 subjects completed the protocol. Among the genuine qigong group, 82% reported less pain by the end of the first training session compared to 45% of control patients. By the last training session, 91% of qigong patients reported analgesia compared to 36% of control patients. Anxiety was reduced in both groups over time, but the reduction was significantly greater in the experimental group than in the control group. CONCLUSIONS: Using a credible placebo to control for nonspecific treatment effects, qigong training was found to result in transient pain reduction and long-term anxiety reduction. The positive findings were not related to preexperimental differences between groups in hypnotizability. Future studies of qigong should control for possible confounding influences and perhaps use clinical disorders more responsive to psychological intervention. AD - Pain Management Center, Newark, NJ, USA. AN - 9893315 AU - Wu, W. H. AU - Bandilla, E. AU - Ciccone, D. S. AU - Yang, J. AU - Cheng, S. C. AU - Carner, N. AU - Wu, Y. AU - Shen, R. DA - Jan DP - NLM ET - 1999/01/20 IS - 1 KW - Adolescent Adult Aged *Breathing Exercises Humans Middle Aged Reflex Sympathetic Dystrophy/*therapy Time Factors Treatment Outcome LA - eng N1 - Wu, W H Bandilla, E Ciccone, D S Yang, J Cheng, S C Carner, N Wu, Y Shen, R R21 00-93-002/PHS HHS/United States Clinical Trial Journal Article Randomized Controlled Trial Research Support, U.S. Gov't, P.H.S. United States Altern Ther Health Med. 1999 Jan;5(1):45-54. PY - 1999 SN - 1078-6791 (Print) 1078-6791 SP - 45-54 ST - Effects of qigong on late-stage complex regional pain syndrome T2 - Altern Ther Health Med TI - Effects of qigong on late-stage complex regional pain syndrome VL - 5 ID - 3536 ER - TY - JOUR AB - OBJECTIVE: To determine the efficacy of laparoscopic excision of visually diagnosed endometriosis in the treatment of chronic pelvic pain. STUDY DESIGN: Sixty-two women with chronic pelvic pain and who underwent laparoscopic excision of visually diagnosed peritoneal lesions suggestive of endometriosis returned postal questionnaires. The main outcomes measures were change in pelvic pain symptoms measured on a continuous and ordinal scale and patient satisfaction following treatment. Secondary outcomes were quality of life, time off work and use of health service resources. RESULTS: 42/62 (68%) women with an average follow up time of 13 months (range 6-38 months) returned completed outcome questionnaires. The mean amount of pelvic pain was reduced following surgery compared to immediately prior to treatment, regardless of the nature of the pain (P<0.05). Overall, 67% (95% CI 50-80%) of women reported improvement in pain symptoms and 71% (95% CI 55-84%) were satisfied with the results of treatment. Satisfaction with treatment was comparable whether the visual diagnosis of peritoneal endometriosis was confirmed histologically or not (62% versus 64%, P=1.0). CONCLUSION: Laparoscopic excision of visually diagnosed endometriosis appears to be efficacious in the treatment of women with chronic pelvic pain. The launch of a long-term randomised controlled trial to confirm these provisional results is now required. AD - Academic Department of Obstetrics & Gynaecology, Birmingham Women's Hospital, Birmingham B15 2TG, UK. AN - 16169150 AU - Wykes, C. B. AU - Clark, T. J. AU - Chakravati, S. AU - Mann, C. H. AU - Gupta, J. K. DA - Mar 1 DO - 10.1016/j.ejogrb.2005.08.008 DP - NLM ET - 2005/09/20 IS - 1 KW - Absenteeism Adolescent Adult Cohort Studies Endometriosis/complications/*surgery Female Humans Laparoscopy/*methods Patient Satisfaction Pelvic Pain/etiology/*surgery Peritoneal Diseases/complications/*surgery Prospective Studies Quality of Life Recurrence *Treatment Outcome LA - eng N1 - Wykes, Catherine B Clark, T Justin Chakravati, Swati Mann, Christopher H Gupta, Janesh K Evaluation Study Journal Article Ireland Eur J Obstet Gynecol Reprod Biol. 2006 Mar 1;125(1):129-33. doi: 10.1016/j.ejogrb.2005.08.008. Epub 2005 Sep 15. PY - 2006 SN - 0301-2115 (Print) 0301-2115 SP - 129-33 ST - Efficacy of laparoscopic excision of visually diagnosed peritoneal endometriosis in the treatment of chronic pelvic pain T2 - Eur J Obstet Gynecol Reprod Biol TI - Efficacy of laparoscopic excision of visually diagnosed peritoneal endometriosis in the treatment of chronic pelvic pain VL - 125 ID - 3392 ER - TY - JOUR AB - Background and AimA strong association between family function and irritable bowel syndrome (IBS) has been observed. Parental rearing styles, as a comprehensive mark for family function, may provide new clues to the etiology of IBS. This study aimed to explore which dimensions of parental rearing styles were risk factors or protective factors for IBS in adolescents. MethodsTwo thousand three hundred twenty adolescents were recruited from one middle school and one high school randomly selected from Jiangan District (an urban district in Wuhan City). Data were collected using two Chinese versions of validated self-report questionnaires including the Rome III diagnostic criteria for pediatric IBS and the Egna Minnen Betraffande Uppfostran: One's Memories of Upbringing for perceived parental rearing styles. ResultsNinety-six subjects diagnosed as pediatric IBS were compared with 1618 controls. The IBS patients reported less both paternal and maternal emotional warmth (all P<0.01) and more both paternal and maternal punishment, overinterference, rejection, and overprotection (only for father) (all P<0.01) than the controls. Furthermore, the IBS patients had higher total scores of parental rearing styles (all P<0.001) than the controls. With univariate logistic regression, standardized regression coefficients and odds ratios of parental rearing variables were calculated. Multivariate logistic regression revealed that paternal rejection (P=0.001) and maternal overinterference (P=0.002) were independent risk factors for IBS in adolescents. ConclusionsParental emotional warmth is a protective factor for IBS in adolescents and parental punishment, overinterference, rejection, and overprotection are risk factors for IBS in adolescents. AN - WOS:000331469400011 AU - Xing, Z. X. AU - Hou, X. H. AU - Zhou, K. AU - Qin, D. Y. AU - Pan, W. DA - Mar DO - 10.1111/jgh.12388 IS - 3 N1 - Xing, Zhouxiong Hou, Xiaohua Zhou, Kan Qin, Diyuan Pan, Wen 1440-1746 PY - 2014 SN - 0815-9319 SP - 463-468 ST - The impact of parental-rearing styles on irritable bowel syndrome in adolescents: A school-based study T2 - Journal of Gastroenterology and Hepatology TI - The impact of parental-rearing styles on irritable bowel syndrome in adolescents: A school-based study UR - ://WOS:000331469400011 VL - 29 ID - 2316 ER - TY - JOUR AB - BACKGROUND Menstruation is unique phenomenon in girls. However, even in today's time in India, it is associated with many taboos and myths that affect many socio-cultural and economic aspects of life and is a hindrance in the overall development of a girl to women and becoming empowered. Besides the taboos, there are menstrual problems which a girl has to suffer. A woman's reproductive health is determined by her menstrual health. The prevalence of menstrual disorders is highest in the 20 to 24-year-old age group and decreases progressively thereafter. They affect not only the woman, but also family, social, and national economics as well. Even girls from good socioeconomic background and education are unable to dispel the taboos and are unable to discuss their menstrual issues and problems due to lack of menstrual education. Information on a woman's menstrual pattern will aid in clinical evaluation of gynaecological problems and will make womanhood easier for adolescent women and adults(1). However, studies on menstrual pattern, menstrual disorders, associated factors and taboos affecting the girls of medical students of university of rural North India are very few. We wanted to determine the menstrual pattern, menstrual disorders, information regarding menstruation and taboos associated with menstruation among female medical students of university of rural North India. METHODS A self-descriptive cross-sectional study was carried out among female medical students between the ages 17-22 years. A total of 235 questionnaires was administered to postmenarcheal Indian adolescent girls attending medical college in SGT University, Gurugram, and Haryana India. Participants were asked to respond to a semi-structured questionnaire on menstrual health awareness. The questionnaire included questions on age at menarche, menstrual cycle length and regularity, duration, and amount of flow, type and severity of pain related to menstruation, need for analgesia, and symptoms suggestive of premenstrual syndrome (PMS), and impact of menstrual pain on academic and social activities and taboos associated with menstruation. The main outcome measure was information regarding menarche, description of menstrual patterns, disorders and impact of the disorder on academic and social activities and taboos regarding menstruation. RESULTS Out of the 235 questionnaires distributed, 200 were retrieved and the information contained in each questionnaire was analysed. The mean age of menarche was 12.59 +/- 1.25 years with a range of 10 to 16 years. The mean age of girls was 19.45 +/- 2.5 years. Mean duration of menstrual flow was 4.77 +/- 1.06 days. It was observed that 146 (72%) respondents had regular length of menstrual cycle whereas 54 (28%) respondents had irregular menstrual cycle, which showed its peak at the age group of 17-19 yrs. (33.3%) between age groups. Of the 146 students with regular menstrual cycle, 88 (60.27%) had average flow while in 40 (27.39%) had scanty, and 18 (12.32%) had heavy menstrual cycle. Of the 54 students who had irregular cycle, prolonged cycles were reported by 42 (77.77%) students, and frequent cycles were reported by 12 (22.22%) students. Dysmenorrhoea was reported in 140 (70%) respondents. Of these, 70 (50%) had mild, 48 (34.28%) had moderate and 22 (15.72%) had severe pain. Premenstrual syndrome was mentioned by 64 (32%) girls. 65 (53.27%) of the dysmenorrheic girls reported that their working ability was affected. 130 (65%) of the girls were aware of menstruation prior to menarche. Mothers, sisters and friends were the main sources of information 148 (74%). 29% missed social activities, and 12.5% missed college, due to menstrual problems. 110 (55%) needed drugs to treat menstrual disorders. 82.5% girls had misconceptions and taboos related to menstruation. CONCLUSIONS Mean age at menarche is in sync with global trend with gradual fall in the age of menarche. There is high prevalence of dysmenorrhoea, PMS, and abnormal menstrual length which requires attention and treatment. These disorders are affecting the working ability, lead to college absenteeism and social withdrawal. Also, even though they are medical students, they still have taboos related to menstruation, which they believe in, and consider many menstrual disorders as normal and are hesitant to come out and discuss with the physician. They are mostly either bearing the problem, or self-medicating. There are many menstrual taboos which are affecting their socio-cultural and economic aspects. Increasing the awareness through educational programs at early age will definitely help the girl in developing confidence and increases self-esteem. AN - WOS:000468630600007 AU - Yadav, B. AU - Taneja, P. DA - Apr DO - 10.14260/jemds/2019/273 IS - 15 N1 - Yadav, Bindoo Taneja, Poonam Yadav, Bindoo/AAK-6654-2021 2278-4802 PY - 2019 SN - 2278-4748 SP - 1232-1236 ST - QUESTIONNAIRE BASED STUDY ON MENSTRUAL PATTERNS AMONG FEMALE MEDICAL UNIVERSITY STUDENTS OF RURAL NORTH INDIA T2 - Journal of Evolution of Medical and Dental Sciences-Jemds TI - QUESTIONNAIRE BASED STUDY ON MENSTRUAL PATTERNS AMONG FEMALE MEDICAL UNIVERSITY STUDENTS OF RURAL NORTH INDIA UR - ://WOS:000468630600007 VL - 8 ID - 1930 ER - TY - JOUR AB - Background Children with JIA may experience difficulty with health related quality of life (HRQOL). The Patient Reported Outcomes Measurement Information System (PROMIS) a patient related outcome (PRO) measure, covers HRQOL domains that include physical function, mental health, and social interactions. During initial use, we found PROMIS identified children with symptoms of depression, sometimes before they shared those feelings with parents or members of the clinic team. We studied the use of PROMIS for this purpose, and to determine what demographic, clinical, and other characteristics might be related to higher depressive symptom scores. Methods From March 2014 - February 2017, at each visit, all JIA patients having met ILAR classification criteria seen by M.L.M. received the PROMIS Short Form 35 v.1.0, as part of routine care. T scores were calculated from raw scores for mobility, anxiety, depressive symptoms, fatigue, peer relationships, and pain interference domains. Data extracted by optical mark recognition software were merged with electronic medical record (EMR data), extracted by Extract/Transform/Load software, including joint counts, visit age, ANA, RF, and HLA-B27 status. Mixed effects models were used to identify significant associations of independent variables with depression T scores. Results Data from 148 patients were analyzed (114 females for 435 visits, 34 males for 118 visits; 13.8 +/- 2.8 years): 70 persistent oligoarthritis, 9 extended oligoarthritis, 19 ERA, 21 polyarthritis (RF-), 5 polyarthritis (RF+), 11 undifferentiated arthritis, 3 psoriatic arthritis, 10 systemic arthritis). T scores showed wide ranges within individual JIA categories, with similar mean scores for all groups. Univariate linear mixed effects models showed significant relationships to depression T scores of gender and race (males and Asian patients with lower T scores, p < .0001, p = 0.091, respectively), joint count (p = 0.002), pain interference score (p = 0.0004), and Patient and Physician Global Assessment (p = 0.004, p < .0001, respectively). No particular JIA category was associated with Depression T scores. HRQOL domains were interrelated (p < .0001), including patients reporting symptoms of depression tending also to report symptoms of anxiety. PROMIS identified 15 patients who did not otherwise report depressive symptoms, but needed referral for counseling; eight did not endorse depressive symptoms until the 2nd or 3rd visit. Only 3 patients had disease flare. Concerns besides arthritis such as parental conflict or school bullying were elicited in 7 patients during interviews with the social worker. All patients expressed being worried about their arthritis. Conclusion PROMIS is useful in screening JIA patients for symptoms of depression, particularly to identify patients who might not otherwise report these symptoms. The other PROMIS domain scores are related to reporting of symptoms of depression, as is Patient and Physician Global Assessment. Future studies will use PROMIS questionnaires incorporated into the EMR, permitting data entry by tablets and an online patient portal. This will make possible comparisons of HRQOL in children with JIA to those with other chronic rheumatic and non-rheumatic diseases. AN - WOS:000592002000001 AU - Yan, Y. F. AU - Rychlik, K. L. AU - Rosenman, M. B. AU - Miller, M. L. C7 - 92 DA - Dec DO - 10.1186/s12969-020-00482-1 IS - 1 N1 - Yan, Yufan Rychlik, Karen L. Rosenman, Marc B. Miller, Michael L. 1546-0096 PY - 2020 ST - Use of PROMIS (R) to screen for depression in children with arthritis T2 - Pediatric Rheumatology TI - Use of PROMIS (R) to screen for depression in children with arthritis UR - ://WOS:000592002000001 VL - 18 ID - 1777 ER - TY - JOUR AB - Soil-transmitted helminth (STH) infections are common. Indeed, more than 1 billion people are affected, mainly in the developing world where poverty prevails and hygiene behavior, water supply, and sanitation are often deficient(1,2). Ascaris lumbricoides, Trichuris trichiura, and the two hookworm species, Ancylostoma duodenale and Necator americanus, are the most prevalent STHs(3). The estimated global burden due to hookworm disease, ascariasis, and trichuriasis is 22.1, 10.5, and 6.4 million disability-adjusted life years (DALYs), respectively(4). Furthermore, an estimated 30-100 million people are infected with Strongyloides stercoralis, the most neglected STH species of global significance which arguably also causes a considerable public health impact(5,6). Multiple-species infections (i.e., different STHs harbored in a single individual) are common, and infections have been linked to lowered productivity and thus economic outlook of developing countries(1,3). For the diagnosis of common STHs, the World Health Organization (WHO) recommends the Kato-Katz technique(7,8), which is a relatively straightforward method for determining the prevalence and intensity of such infections. It facilitates the detection of parasite eggs that infected subjects pass in their feces. With regard to the diagnosis of S. stercoralis, there is currently no simple and accurate tool available. The Baermann technique is the most widely employed method for its diagnosis. The principle behind the Baermann technique is that active S. stercoralis larvae migrate out of an illuminated fresh fecal sample as the larvae are phototactic(9). It requires less sophisticated laboratory materials and is less time consuming than culture and immunological methods(5). Morbidities associated with STH infections range from acute but common symptoms, such as abdominal pain, diarrhea, and pruritus, to chronic symptoms, such as anemia, under-and malnutrition, and cognitive impairment(10). Since the symptoms are generally unspecific and subtle, they often go unnoticed, are considered a normal condition by affected individuals, or are treated as symptoms of other diseases that might be more common in a given setting. Hence, it is conceivable that the true burden of STH infections is underestimated by assessment tools relying on self-declared signs and symptoms as is usually the case in population-based surveys. In the late 1980s and early 1990s, Stephenson and colleagues highlighted the possibility of STH infections lowering the physical fitness of boys aged 6-12 years(11,12). This line of scientific inquiry gained new momentum recently(13,14,15). The 20-meter (m) shuttle run test was developed and validated by Leger et al.(16) and is used worldwide to measure the aerobic fitness of children(17). The test is easy to standardize and can be performed wherever a 20-m long and flat running course and an audio source are available, making its use attractive in resource-constrained settings(13). To facilitate and standardize attempts at assessing whether STH infections have an effect on the physical fitness of school-aged children, we present methodologies that diagnose STH infections or measure physical fitness that are simple to execute and yet, provide accurate and reproducible outcomes. This will help to generate new evidence regarding the health impact of STH infections. AN - WOS:000209225000015 AU - Yap, P. AU - Furst, T. AU - Muller, I. AU - Kriemler, S. AU - Utzinger, J. AU - Steinmann, P. C7 - e3966 DA - Aug DO - 10.3791/3966 IS - 66 N1 - Yap, Peiling Fuerst, Thomas Mueller, Ivan Kriemler, Susi Utzinger, Juerg Steinmann, Peter Muller, Ivan/B-6496-2017 Muller, Ivan/0000-0002-6397-9979 PY - 2012 SN - 1940-087X ST - Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children T2 - Jove-Journal of Visualized Experiments TI - Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children UR - ://WOS:000209225000015 ID - 2422 ER - TY - JOUR AB - BACKGROUND: The aim of this study is to investigate the associations between migraine related disability and somatosensory amplification, depression, anxiety, and stress. METHOD: Fifty-five migraine patients who applied to the outpatient unit of the Neurology Department of Acibadem University School of Medicine, Maslak Hospital in Istanbul, Turkey, and twenty-eight subjects without migraine were recruited for the study. The participants were asked to complete a sociodemographic form, Migraine Disability Assessment Scale (MIDAS), Depression Anxiety Stress Scale, Somatosensory Amplification Scale (SSAS). RESULTS: Somatosensory amplification scores were significantly higher in the migraineurs than in the control group (29.85+/-6.63 vs 26.07+/-7.1; p=0.027). Somatosensory amplification scores and depression scores were significantly higher in migraineurs with moderate and severe disability than in patients with minimal and mild disability (31.7+/-6.4 vs 27.71+/-5.49; p=0.01, 11.27+/-8.7 vs 7.38+/-8.11; p=0.04, respectively). A significant positive correlation was found between the frequency of migraine attacks for at least three consecutive months (MIDAS A scores) and the SSAS scores (r=0.363, p=0.007) in migraineurs. The MIDAS total scores were also significantly correlated with the DASS depression subcale scores (r=0.267, p=0.04), and the DASS stress subscale scores (r=0.268, p=0.05). CONCLUSION: Psychological factors, and vulnerability to bodily sensations may incease the burden of migraine. We point out that the timely assessing of somatic amplification and the evaluation of mental status would help improve the quality of life of in migraineurs. AD - Department of Psychiatry, Acibadem University School of Medicine, Istanbul, Turkey. burcugoksan@gmail.com AN - 23799958 AU - Yavuz, B. G. AU - Aydinlar, E. I. AU - Dikmen, P. Y. AU - Incesu, C. C2 - PMC3695888 DA - Jun 25 DO - 10.1186/1129-2377-14-53 DP - NLM ET - 2013/06/27 IS - 1 KW - Adolescent Adult Anxiety/*complications Depression/*complications Female Humans Male Middle Aged Migraine Disorders/complications/*psychology Sensation Disorders/*complications Stress, Psychological/*complications Surveys and Questionnaires Turkey Young Adult LA - eng N1 - 1129-2377 Yavuz, Burcu Goksan Aydinlar, Elif Ilgaz Dikmen, Pinar Yalinay Incesu, Cem Journal Article J Headache Pain. 2013 Jun 25;14(1):53. doi: 10.1186/1129-2377-14-53. PY - 2013 SN - 1129-2369 (Print) 1129-2369 SP - 53 ST - Association between somatic amplification, anxiety, depression, stress and migraine T2 - J Headache Pain TI - Association between somatic amplification, anxiety, depression, stress and migraine VL - 14 ID - 3716 ER - TY - JOUR AB - Objective: To investigate the effect of alexithymic personality characteristics, and associated mental problems on somatization in adolescents. Methods: This research was conducted on 773 students (49% female, n=376; 51% male, n=397) aged between 11 and 17. The students were recruited from two state schools in Istanbul. DSM-5 Level 2 Somatic Symptom Scale Child Form, 20 item Toronto Alexithymia Scale (TAS-20), and Strengths and Difficulties Questionnaire (SDQ) self-report form were used as measures. The mean scores of the scales between female and male groups were compared with independent sample t test. The correlations between the scales were analyzed with Pearson's product moment correlation test. The predictability of total scores of TAS-20 and SDQ, and SDQ subscale scores on somatization scores was evaluated with multivariate linear regression analysis. Results: The somatization scores of females were higher than males, significantly. Somatization scores were positively correlated with alexithymia, SDQ total scores, emotional problems, behavior problems, inattention/hyperactivity, and peer relation problems scores, significantly. The results of regression analysis indicated that alexithymia, emotional problems, behavior problems and age significantly predict the somatization levels. Conclusion: It is suggested that therapeutic interventions aiming to improve of emotional identification and expressions may help us to increase the success of somatization treatment in adolescents. Additionally, focusing on emotional problems such as depressive symptoms and elevated anxiety levels, and behavioral problems may also increase the success of treatment. AN - WOS:000466904700012 AU - Yavuz, M. AU - Erdur, B. AU - Isik, M. AU - Bogday, H. AU - Ince, H. E. AU - Kok, O. AU - Onal Sonmez, A. DA - Jun DO - 10.5455/apd.3992 IS - 3 N1 - Yavuz, Mesut Erdur, Burcu Isik, Merve Bogday, Hayat Ince, Hazal Ezgi Kok, Ozlem Onal Sonmez, Arzu Yavuz, Mesut/ABG-8440-2020 Yavuz, Mesut/0000-0002-8957-6510 PY - 2019 SN - 1302-6631 SP - 321-326 ST - The associations between somatization, alexithymia, and mental problems in adolescents T2 - Anadolu Psikiyatri Dergisi-Anatolian Journal of Psychiatry TI - The associations between somatization, alexithymia, and mental problems in adolescents UR - ://WOS:000466904700012 VL - 20 ID - 1920 ER - TY - JOUR AB - OBJECTIVES: Primary dysmenorrhea is a common problem among menstruating adolescents and young women. It may cause physical distress and result in school absenteeism and reduced physical activity. This study aimed to evaluate the effects of auricular acupressure on menstrual pain and distress in adolescents with dysmenorrhea. DESIGN: A single-blind, placebo-controlled design was used. SETTING/LOCATION: Participants were obtained from one senior high school in northern Taiwan. SUBJECTS: One hundred and thirteen (113) adolescent participants with primary dysmenorrhea were recruited and assigned to the experimental or control group by a coin toss. INTERVENTION: The experimental group received auricular acupressure applied to six true acupoints (shenmen, Kidney, Liver, Internal Genitals, Central Rim, and Endocrine). The control group received six sham acupoints without effects on dysmenorrhea. All participants were instructed to press each acupoint for 1 minute, 4 times a day for 2 days. OUTCOME MEASURES: The outcomes were assessed by rating dysmenorrhea severity on a visual analogue scale (VAS) and using the Short-Form McGill Pain Questionnaire (SF-MPQ) and Menstrual Distress Questionnaire (MDQ). RESULTS: Between-group differences were found in VAS and MDQ after the interventions. Within-group differences were found in the score changes of VAS, MDQ, and SF-MPQ during the interventions for both groups. CONCLUSIONS: Auricular acupressure relieves menstrual pain and distress in high-school adolescents. The findings may serve as a basis for using auricular acupressure to treat dysmenorrhea in adolescents. There was pain reduction with sham as well as with true acupoint acupressure, but the latter was significantly greater. The sham acupoint may not be used as a control for auricular acupoint and qualitative evaluation of dysmenorrhea should be added to the evaluation by SF-MPQ in future studies. AD - School of Nursing, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan, ROC. AN - 23130943 AU - Yeh, M. L. AU - Hung, Y. L. AU - Chen, H. H. AU - Wang, Y. J. DA - Apr DO - 10.1089/acm.2011.0665 DP - NLM ET - 2012/11/08 IS - 4 KW - Acupressure/*methods *Acupuncture Points Adolescent Dysmenorrhea/*therapy *Ear Female Humans Pain Management/*methods Severity of Illness Index Single-Blind Method Surveys and Questionnaires LA - eng N1 - 1557-7708 Yeh, Mei-Ling Hung, Yu-Ling Chen, Hsing-Hsia Wang, Yu-Jen Journal Article Randomized Controlled Trial United States J Altern Complement Med. 2013 Apr;19(4):313-8. doi: 10.1089/acm.2011.0665. Epub 2012 Nov 6. PY - 2013 SN - 1075-5535 SP - 313-8 ST - Auricular acupressure for pain relief in adolescents with dysmenorrhea: a placebo-controlled study T2 - J Altern Complement Med TI - Auricular acupressure for pain relief in adolescents with dysmenorrhea: a placebo-controlled study VL - 19 ID - 3656 ER - TY - JOUR AB - The prevalence of chronic pain is well described in various parts of the world; primarily in Western societies such as Europe, America and Australia. Little is known of the prevalence of chronic pain within Asia or Southeast Asia. In view of the cultural and genetic variation in pain causation, manifestation and reporting, the findings of previous studies cannot be translated to Asian countries. Prevalence studies needed to be carried out to quantify the magnitude and impact of chronic pain within Asian countries to properly allocate precious health funds to deal with this important healthcare issue. We report the findings of the prevalence study within one Asian country: Singapore. OBJECTIVE: To determine the prevalence and impact of chronic pain in adult Singaporeans. MATERIALS AND METHODS: Two sets of questionnaires were designed. The first, a screening questionnaire, to identify the prevalence of chronic pain, and should there be chronic pain; the second, a detailed questionnaire was administered, to characterise the features and the impact of pain. A cross-sectional sampling of Singapore adults were achieved using a computer-based multi-step random sampling of listed telephones numbers. The questionnaires were administered via telephone by a trained interviewer with the aid of a computer-assisted telephone interview system. RESULTS: A total of 4141 screening and 400 detailed questionnaires were completed. The prevalence of chronic pain, defined as pain of at least 3 months' duration over the last 6 months was 8.7% (n = 359). There was a higher prevalence in females (10.9%) and with increasing age. In particular, pain prevalence increased steeply beyond the age of 65 years old. There was a significant impact on work and daily function of those with chronic pain. CONCLUSION: Though the prevalence of chronic pain was marginally lower compared other studies, the impact of pain was just as significant. In a rapidly ageing population such as Singapore, chronic pain is an important emerging healthcare problem which will likely exert increasing toll on the existing social infrastructure within the next 5 to 10 years. AD - The Pain Specialists, Mount Elizabeth Hospital, Singapore. AN - 19956814 AU - Yeo, S. N. AU - Tay, K. H. DA - Nov DP - NLM ET - 2009/12/04 IS - 11 KW - Absenteeism Adolescent Adult Aged Aged, 80 and over Cross-Sectional Studies Female Humans Income Male Middle Aged Pain, Intractable/*epidemiology/physiopathology Singapore/epidemiology Surveys and Questionnaires Young Adult LA - eng N1 - Yeo, Sow Nam Tay, Kwang Hui Journal Article Research Support, Non-U.S. Gov't Singapore Ann Acad Med Singap. 2009 Nov;38(11):937-42. PY - 2009 SN - 0304-4602 (Print) 0304-4602 SP - 937-42 ST - Pain prevalence in Singapore T2 - Ann Acad Med Singap TI - Pain prevalence in Singapore VL - 38 ID - 3130 ER - TY - JOUR AB - This study aims to elucidate the effects of BMI (Body Mass Index), age, gender, personality traits, sleep problems, family history of headache, and hobbies on primary headaches in school children in Mugla. The study also intends to discuss the association of headaches with the courses and tests using monthly follow-up forms. A cross-sectional school-based study was performed on 511 school children (aged 8-15) between January and May 2012 in Mugla. Potential triggering and aggravating demographic and social variables were investigated based on a diagnosis of ICHD-II migraine. The prevalence of recurrent headache was found to be 31.7% in Mugla. Of the studied population, 17.6% had tension-type headache (TTH), 8.84% had migraine, and 5.3% had mixed headache symptoms suggesting both TTH and migraine. Headaches were found to be more common among girls. Using logistic regression analysis, we found that increasing age, increased BMI values, presence of siblings, family history of headache (especially maternal), sensitive personality traits (especially vulnerable children), and sleep problems had a statistically significant effect on headaches in children. Additionally, Mondays and particularly math test dates were found to increase the occurrence on headache in school children. In contrast, hobbies were found not to have any significant effects on headaches. As a common healthcare problem, migraine and TTH are prevalent among school children. Primary headache disorders of school children included family history of headache, personality traits, school life, increased values of BMI, sleep problems, but not hobbies in our study population. Lifestyle-coping strategies are essential for school children. AN - WOS:000337927200014 AU - Yilmaz, M. AU - Picakciefe, M. AU - Ozge, A. AU - Palali, I. IS - 3 N1 - Yilmaz, Mustafa Picakciefe, Metin Ozge, Aynur Palali, Irfan PY - 2013 SN - 0393-6384 SP - 419-424 ST - MIGRAINE AND TENSION-TYPE HEADACHE IN SCHOOLCHILDREN IN WESTERN OF TURKEY T2 - Acta Medica Mediterranea TI - MIGRAINE AND TENSION-TYPE HEADACHE IN SCHOOLCHILDREN IN WESTERN OF TURKEY UR - ://WOS:000337927200014 VL - 29 ID - 2389 ER - TY - JOUR AB - Juvenile fibromyalgia (JFM) is a disease in which patients complain of acute and chronic severe pain, an overt primary cause for which cannot be found or surmised. Although patients with JFM mainly complain of systemic pain or allodynia in the medical interview and physical examination, the concept of the disease is the total sum of painful illness, chronic fatigue, hypothermia and many other autonomic symptoms and signs. Many issues are interacting including individual traits (personality, temperament, sensitivity, memory of pain; age: early adolescence), individual states (self-esteem, anxiety, developmental level), and external stressors (parent especially mother, school environment). JFM is diagnosed on the combination of disease history, physical examination to determine the 18 tender points and allodynia, pain from gently touching their hair, and negative results of blood tests (inflammatory markers, thyroid function, myogenic enzymes). The goals of treatment are the following: restoration of function and relief of pain. Psychological support is advocated. Although the exact number of patients with JFM is still to be elucidated, it seems to be growing because pediatric rheumatologists in Japan encounter children with a wide variety of musculoskeletal pains. This guideline describes how to diagnose JFM in children and how to treat them appropriately. AD - Department of Pediatrics, Yokohama City University School of Medicine, Yokohama, Japan. syokota@med.yokohama-cu.ac.jp AN - 23758613 AU - Yokota, S. AU - Kikuchi, M. AU - Miyamae, T. DA - Aug DO - 10.1111/ped.12155 DP - NLM ET - 2013/06/14 IS - 4 KW - Diagnosis, Differential *Disease Management Fibromyalgia/*diagnosis/*therapy Humans *Practice Guidelines as Topic allodynia central pain child fibromyalgia tender points LA - eng N1 - 1442-200x Yokota, Shumpei Kikuchi, Masako Miyamae, Takako Journal Article Review Australia Pediatr Int. 2013 Aug;55(4):403-9. doi: 10.1111/ped.12155. PY - 2013 SN - 1328-8067 SP - 403-9 ST - Juvenile fibromyalgia: Guidance for management T2 - Pediatr Int TI - Juvenile fibromyalgia: Guidance for management VL - 55 ID - 3026 ER - TY - JOUR AB - Objective: Non-cardiac chest pain is a common and persistent problem for children; yet, typically, there is no clear medical cause. To date, no behavioural and/or psychological factors have been studied to explain chest pain in a pre-school paediatric sample. We hypothesized that pre-school children with medically unexplained chest pain would have higher rates of behavioural problems compared to healthy controls. Methods: We assessed 41 pre-school children with non-cardiac chest pain and 68 age matched children with benign heart murmurs as the control group using the Child Behaviour Check List-1 1/2-5 to evaluate emotional and behavioural problems. Results: Internalizing problem scores comprising emotionally reactive, anxiety/depression, and somatic complaints were higher in children with non-cardiac chest pain than in the control group. Among the possible factors, the factor that is related to behaviour problem scores, in univariate analysis, was a significant and inverse correlation between maternal education and behaviour problem scores. Also, maternal employment status was associated with behavioural problems. Children with a housewife mother were more susceptible to having such behavioural problems. Based on multiple regression analyses, being in the non-cardiac chest pain group was found to be significantly related to internalizing problems in our total sample. Conclusions: These results suggest that pre-school children with non-cardiac chest pain may experience increased levels of certain behavioural comorbidities. Systematic behavioural screening could increase the detection of behavioural problems and improve care for this population. Future studies of non-cardiac chest pain in pre-school children should include larger samples and comprehensive diagnostic assessments as well as long-term follow-up evaluations. AN - WOS:000612796400007 AU - Yoldas, T. AU - Yoldas, T. C. AU - Beyazal, M. AU - Sayici, U. I. AU - Orun, U. A. C7 - Pii s1047951120001948 DA - Sep DO - 10.1017/s1047951120001948 IS - 9 N1 - Yoldas, Tamer Yoldas, Tuba Celen Beyazal, Meryem Sayici, Ufuk I. Orun, Utku A. Yoldemir, Tevfik/AAA-3506-2019; ATASAYAN, KEMAL/B-7102-2019 Yoldemir, Tevfik/0000-0001-6925-4154; ATASAYAN, KEMAL/0000-0002-4862-4352 1467-1107 PY - 2020 SN - 1047-9511 SP - 1261-1265 ST - Relationship between non-cardiac chest pain and internalizing problems in pre-school aged children T2 - Cardiology in the Young TI - Relationship between non-cardiac chest pain and internalizing problems in pre-school aged children UR - ://WOS:000612796400007 VL - 30 ID - 1798 ER - TY - JOUR AB - Background/Ainis: The role of ultrasonography in diagnosing non-perforated appendicitis:in young children is reviewed. Methodology: Between, January 1997 and September 1999, three children with abdominal pain due to non-perforated appendicitis were, admitted to the Nippon Medical School Hospital. Ultrasonography of the right lower quadrant was performed using a: 7.5-MHz curved array transducer with, the graded compression technique. Results: Edema of the appendix was detected in all cases. The appendiceal diameter Was 9 to 18 mm, and the thickness of the muscular Wall was 3.5 to 6mm. An echogenic submucosal layer, increased periappendiceal echogenicity, and the acoustic shadow of the proximal appendix was detected in each case. Localized fluid collection was not observed in any patient. Surgical and. histopathological findings were nonperforated gangrenous appendicitis with fecal stone in all three cases. Conclusions: Ultrasonography provides valuable clinical information about, the ileocecal region in children with acute abdominal pain. Even when the clinical diagnosis seems well established, performing ultrasonography routinely may help reduce the rate of perforation by decreasing the time required to establish the diagnosis. AN - WOS:000177965800027 AU - Yoshida, H. AU - Onda, M. AU - Tajiri, T. AU - Mamada, Y. AU - Taniai, N. AU - Koizumi, M. AU - Yoshimura, K. AU - Takasaki, H. AU - Furukawa, K. DA - Sep-Oct IS - 47 N1 - Yoshida, H Onda, M Tajiri, T Mamada, Y Taniai, N Koizumi, M Yoshimura, K Takasaki, H Furukawa, K PY - 2002 SN - 0172-6390 SP - 1293-1295 ST - Ultrasonography of non-perforated appendicitis in young children T2 - Hepato-Gastroenterology TI - Ultrasonography of non-perforated appendicitis in young children UR - ://WOS:000177965800027 VL - 49 ID - 2824 ER - TY - JOUR AB - INTRODUCTION: Medial malleolar stress fractures are relatively uncommon. This report describes the successful treatment of nonunion of a medial malleolar stress fracture due to chronic lateral ankle instability. PRESENTATION OF CASE: A 13-year-old middle school student who belonged to a football club presented to our clinic with chronic medial left ankle pain lasting over a year. He had sprained his left ankle several times 6 years earlier. A plain anteroposterior ankle radiograph showed a vertical fracture line in the medial malleolus involving the epiphyseal plate, and computed tomography demonstrated the vertical fracture seen on the plain radiographs and bone sclerosis at the fracture site. We performed internal fixation for nonunion of the medial malleolar stress fracture with arthroscopic modified Brostrom for lateral ankle instability. Two years after surgery, the Self-Administered Foot Evaluation Questionnaire improved in all parameters, and both the anterior drawer and varus stress tests were negative. DISCUSSION: Early diagnosis of medial malleolar stress fracture is important for a rapid return to sports. Magnetic resonance imaging is helpful for early diagnosis. Because lateral ankle instability can cause medial malleolar stress fracture, arthroscopic modified Brostrom procedure is meaningful for medial malleolar stress fracture with lateral ankle instability. CONCLUSION: Internal fixation and the arthroscopic modified Brostrom procedure could achieve good clinical outcomes for medial malleolar stress fractures with lateral ankle instability. (C) 2020 The Authors. Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. This is an open access article under the CC BY-NC-ND license (http://creative commons.org/licenses/by-nc-nd/4.0/). AN - WOS:000608403500033 AU - Yoshimoto, K. AU - Noguchi, M. AU - Maruki, H. AU - Ishibashi, M. AU - Okazaki, K. DO - 10.1016/j.ijscr.2020.12.043 N1 - Yoshimoto, Kensei Noguchi, Masahiko Maruki, Hideyuki Ishibashi, Mina Okazaki, Ken Okazaki, Ken/0000-0003-1274-8406; xian sheng, ji ben/0000-0003-0658-5727 PY - 2021 SN - 2210-2612 SP - 235-240 ST - Nonunion of a medial malleolar stress fracture in an adolescent athlete secondary to lateral ankle instability: A case report T2 - International Journal of Surgery Case Reports TI - Nonunion of a medial malleolar stress fracture in an adolescent athlete secondary to lateral ankle instability: A case report UR - ://WOS:000608403500033 VL - 78 ID - 1770 ER - TY - JOUR AB - OBJECTIVES: Although pediatric patients with chronic pain often turn to complementary therapies, little is known about patients who seek academic integrative pediatric care. DESIGN: The study design comprised abstraction of intake forms and physician records from new patients whose primary concern was pain. SETTING/LOCATION: The study setting was an academic pediatric clinic between January 2010 and December 2011. SUBJECTS: Of the 110 new patients, 49 (45%) had a primary concern about headache (20), abdominal pain (18), or musculoskeletal pain (11). RESULTS: The average age was 13±4 years, and 37% were male. Patients reported an average pain level of 6±3 on a 10-point scale, and most reported more than one kind of pain; parents had an average of 7±3 health concerns per child, including fatigue (47%), mood or anxiety (45%), constipation/diarrhea (41%), and/or sleep problems (35%). Most patients (57%) were referred by specialists; 71% were taking prescription medications; and 53% were taking one or more dietary supplements at intake. Of those tested, most (61%) had suboptimal vitamin D levels. All families wanted additional counseling about diet (76%), exercise (66%), sleep (58%), and/or stress management (81%). In addition to encouraging continued medical care (100%) and referral to other medical specialists (16%), frequent advice included continuing or initiating dietary supplements such as vitamins/minerals (80%), omega-3 fatty acids (67%), and probiotics (31%). Stress-reducing recommendations included biofeedback (33%), gratitude journals (16%), and yoga/t'ai chi (8%). Other referrals included acupuncture (24%) and massage (20%). DISCUSSION: Patients who have chronic pain and who present to an integrative clinic frequently have complex conditions and care. They are interested in promoting a healthy lifestyle, reducing stress, and using selected complementary therapies. CONCLUSION: Patients with chronic pain who seek integrative care may benefit from the kind of coordinated, integrated, comprehensive care provided in a medical home. AD - Center for Integrative Medicine, Pediatrics, Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA. AN - 23448120 AU - Young, L. AU - Kemper, K. J. DA - Jul DO - 10.1089/acm.2012.0368 DP - NLM ET - 2013/03/02 IS - 7 KW - Abdominal Pain/epidemiology/therapy Adolescent Child Chronic Pain/epidemiology/*therapy Cohort Studies Combined Modality Therapy Comorbidity *Complementary Therapies *Cooperative Behavior Cross-Sectional Studies Female Headache/epidemiology/therapy Humans *Integrative Medicine *Interdisciplinary Communication Male Musculoskeletal Pain/epidemiology/therapy Pain Measurement *Patient Care Team Quality of Life LA - eng N1 - 1557-7708 Young, Lari Kemper, Kathi J Journal Article United States J Altern Complement Med. 2013 Jul;19(7):627-32. doi: 10.1089/acm.2012.0368. Epub 2013 Feb 28. PY - 2013 SN - 1075-5535 SP - 627-32 ST - Integrative care for pediatric patients with pain T2 - J Altern Complement Med TI - Integrative care for pediatric patients with pain VL - 19 ID - 3127 ER - TY - JOUR AB - Background: Femoroacetabular Impingement (FAI) is a common cause of hip pain in adolescent patients. Clinical exam and radiographic markers, such as alpha angle and lateral center edge angle (LCEA), are commonly used to aid in the diagnosis of this condition. The purpose of this study was to correlate preoperative alpha angle and LCEA with preoperative symptoms, intraoperative findings, and preoperative and postoperative patient reported outcomes (PROs) in the adolescent patient. Methods: A retrospective analysis of prospectively collected data was conducted for all patients who underwent operative intervention for FAI at an academic institution over an 11-year period. Preoperative imaging was obtained and measured for LCEA and alpha angle. PROs (modified Harris Hip Score, Hip Disability and Osteoarthritis Outcome Score, and UCLA score) were collected preoperatively, as well as 1, 2, and 5 years postoperatively. Operative intervention was either open surgical hip dislocation or arthroscopic, and intraoperative disease was graded using the Beck Classification system. Patients with minimum 1-year follow-up were included in statistical analysis. Results: There were 86 hips (64 female hips) included with an average age of 16.3 years (range, 10.4 to 20.5 y), with an average of 37 months of follow-up. There was no correlation between severity of preoperative symptoms or difference between pre and postoperative PROs for both alpha angle and LCEA. Overall, significant improvement was noted in modified Harris Hip Score, Hip Disability and Osteoarthritis Outcome Score, and UCLA Score (P<0.001 for each). Independent of preoperative symptoms, increased alpha angle correlated with more severe intraoperative labral disease (P<0.001), and longer length of labral tear (Corr 0.295, P<0.01). Femoral head and acetabular articular cartilage damage did not correlate with alpha angle or LCEA, nor did overall severity of disease. Conclusions: In adolescent patients with FAI, increased alpha angle was found to significantly correlate with labral pathology, including increased length of tear and severity of disease, irrespective of preoperative symptoms or postoperative patient reported outcomes. AN - WOS:000609618900004 AU - Youngman, T. R. AU - Wagner, K. J. AU - Montanez, B. AU - Johnson, B. L. AU - Wilson, P. L. AU - Morris, W. Z. AU - Sucato, D. J. AU - Podeszwa, D. A. AU - Ellis, H. B. DA - Feb DO - 10.1097/bpo.0000000000001703 IS - 2 N1 - Youngman, Tyler R. Wagner, K. John, III Montanez, Benjamin Johnson, Benjamin L. Wilson, Phillip L. Morris, William Z. Sucato, Daniel J. Podeszwa, David A. Ellis Jr, Henry B. Morris, William/AAK-9818-2021 Youngman, Tyler/0000-0002-7009-284X 1539-2570 PY - 2021 SN - 0271-6798 SP - 88-92 ST - The Association of alpha Angle on Disease Severity in Adolescent Femoroacetabular Impingement T2 - Journal of Pediatric Orthopaedics TI - The Association of alpha Angle on Disease Severity in Adolescent Femoroacetabular Impingement UR - ://WOS:000609618900004 VL - 41 ID - 1762 ER - TY - JOUR AB - Background & Aims: Abdominal pain is common in adolescence. The aim of this study was to determine the prevalence of depressive symptoms in a large cohort of patients with frequent abdominal pain. Methods: A prospective, cross-sectional, nationally representative sample of children aged 13 to 18 years (mean age, 16.2 +/- 1.7 y; 49% male) completed in-home interviews and separate in-school questionnaires for the National Longitudinal Study in Adolescent Health (the Add Health Study). Depressed mood was assessed with the Center for Epidemiologic Studies Depression Scale. Subjective measures of abdominal pain were reported by 20,745 adolescents from wave 1 of the Add Health Study. Frequency of abdominal pain over the previous I year was rated as rare (0-1 episode/wk), moderate (2-3 episodes/wk), or daily (>= 4 episodes/wk). Results : Daily pain is reported in 3.2% of adolescents' with an additional 14% reporting pain as moderate in frequency. Sixteen percent of all adolescents are at risk for developing depression. The risk for depression goes from 16% to 45% (P < .001) when the pain is daily. Compared with rare pain, children with daily pain were more likely to miss school 10 or more times per year (46% vs 19%, P < .001), cry (12.1% vs 1%, P < .001), feel sad (25.2% vs 5.3%, P < .001), and lonely (25.2% vs 6.4%, P < .001). Children with daily pain were likely to consider life a failure versus those with no pain (10.2% vs 3.3%, P < .001). Conclusions: Adolescents with frequent abdominal pain are at increased risk for depressive symptoms, social isolation, and missing school. AN - WOS:000253961100014 AU - Youssef, N. N. AU - Atienza, K. AU - Langseder, A. L. AU - Strauss, R. S. DA - Mar DO - 10.1016/j.cgh.2007.12.019 IS - 3 N1 - Youssef, Nader N. Atienza, Katherine Langseder, Annette L. Strauss, Richard S. 1542-7714 PY - 2008 SN - 1542-3565 SP - 329-332 ST - Chronic abdominal pain and depressive symptoms: Analysis of the national longitudinal study of adolescent health T2 - Clinical Gastroenterology and Hepatology TI - Chronic abdominal pain and depressive symptoms: Analysis of the national longitudinal study of adolescent health UR - ://WOS:000253961100014 VL - 6 ID - 2657 ER - TY - JOUR AB - Objective: The aim of this study was to assess the efficacy of a cognitive-behavioral approach to the treatment of recurrent abdominal pain caused by childhood functional gastrointestinal disorders (FGIDs). Methods: From September 2001 to December 2002, 18 patients (12 male; mean age, 12.1 +/- 4.9 years) with chronic abdominal pain (mean duration, 11.8 +/- 13.3 months) caused by FGIDs were referred to our facility's mind-body institute (MBI). Treatment included guided imagery and progressive relaxation techniques. The mean number of sessions per patient was 4.3 +/- 3.4. Outcomes included change in abdominal pain and quality of life, evaluated by the Pediatric Quality of Life Scale (PedsQL(R)). Follow-up was 10.6 +/- 2.3 months after the last MBI session. Results: Abdominal pain improved in 89% of patients; weekly pain episodes decreased from 5.5 +/- 0.9 to 2.0 +/- 2.7 (P < 0.05); pain intensity (0 to 3 scale) decreased from 2.7 +/- 0.6 to 0.6 +/- 0.7 (P < 0.04); missed school days/month decreased from 4.6 +/- 1.7 to 1.4 +/- 3.2 (P < 0.05); social activities/week increased from 0.3 +/- 0.6 to 1.3 +/- 0.6 (P < 0.05); physician office contacts/year decreased from 24 +/- 10.2 to 8.7 +/- 13.1 (P = 0.07). PedsQL(R) scores (0 to 100 scale) improved from 55.3 +/- 11.9 to 80.0 +/- 10.7 (P < 0.03). Conclusions: Guided imagery and progressive relaxation can safely and effectively reduce chronic abdominal pain in children with FGIDs. This treatment also improved social functioning and school attendance. (C) 2004 Lippincott Williams Wilkins. AN - WOS:000222973900013 AU - Youssef, N. N. AU - Rosh, J. R. AU - Loughran, M. AU - Schuckalo, S. G. AU - Cotter, T. N. AU - Verga, B. G. AU - Mones, R. L. DA - Aug DO - 10.1097/00005176-200408000-00013 IS - 2 N1 - Youssef, NN Rosh, JR Loughran, M Schuckalo, SG Cotter, TN Verga, BG Mones, RL 1536-4801 PY - 2004 SN - 0277-2116 SP - 192-196 ST - Treatment of functional abdominal pain in childhood with cognitive behavioral strategies T2 - Journal of Pediatric Gastroenterology and Nutrition TI - Treatment of functional abdominal pain in childhood with cognitive behavioral strategies UR - ://WOS:000222973900013 VL - 39 ID - 2788 ER - TY - JOUR AB - Study Objective: To determine the cross-sectional characteristics of menstruating girls, dysmenorrhea, and the frequencies of related problems. Design: Descriptive, cross-sectional study. Setting: Randomly selected primary, junior, and high schools in the city center of Kayseri. Participants: Two thousand female adolescents of ages between 9 and 18 years. Main Outcome Measures: We used a questionnaire addressing the epidemiological characteristics of menstruation, such as age at menarche, duration of menstrual intervals, average days of bleeding, and any menstrual problems and their frequencies. Results: This study consists of a sufficient number of participants from all age groups. Of the participant (n = 2000) girls, 63.7% (n = 1274) had started menstruating. The mean age at menarche was 12.74 (+/- 1.03) years. With a prevalence of 84.8% (n 5 1080), dysmenorrhea was the most prevalent menstrual problem and the average pain score was 5.87 (+/- 2.45). Of the menstruating girls, 34% (n = 439) used painkillers, the most commonly used was acetaminophen; during their period the prevalence of nonmedical methods to relieve pain was 35.2%; the rate of seeking medical help for dysmenorrhea was 9.3% (n = 119). In menstruating participants, 90.8% discussed their menstrual problems with their mothers. The rate of school absenteeism in menstruating girls was 15.9% in general and 18% in those with dysmenorrhea. Conclusion: Problems related to menstruation are common in adolescents and these problems affect their social life. In adolescent girls, the most common menstrual problem is dysmenorrhea and it affects school performance and attendance. Girls with menstrual problems showed a low rate of seeking medical help. AN - WOS:000434973600005 AU - Yucel, G. AU - Kendirci, M. AU - Gul, U. DA - Aug DO - 10.1016/j.jpag.2018.03.002 IS - 4 N1 - Yucel, Gul Kendirci, Mustafa Gul, Ulku Siraz, Ulku Gul/AAL-1515-2021 Siraz, Ulku Gul/0000-0001-7708-3498 1873-4332 PY - 2018 SN - 1083-3188 SP - 350-355 ST - Menstrual Characteristics and Related Problems in 9-to 18-Year-Old Turkish School Girls T2 - Journal of Pediatric and Adolescent Gynecology TI - Menstrual Characteristics and Related Problems in 9-to 18-Year-Old Turkish School Girls UR - ://WOS:000434973600005 VL - 31 ID - 2004 ER - TY - JOUR AB - Primary fibromyalgia syndrome (PFS) is a common and characteristic rheumatologic condition manifested by diffuse musculoskeletal aches, pains, and stiffness frequently modulated by various factors, e.g., weather, physical activity, sleep quality, and anxiety/stress, and accompanied by discrete tender points at typical soft tissue sites. Although well-recognized in adults, this entity has not been reported separately in juveniles. This study documents PFS in 33 juveniles who presented at age 17 or younger and compares their findings with those in age- and sex-matched normal control subjects. As in adult PFS patients, associated non-musculoskeletal symptoms were common, including fatigue, poor sleep, anxiety/stress, headaches, and paresthesias. Physical examination revealed multiple tender points at characteristic soft tissue sites and no objective evidence of arthritis. Routine laboratory test results were normal or negative. Juvenile PFS is often misdiagnosed. Recognition of this common rheumatologic condition in juveniles is important in order to avoid unwarranted investigations and improper management. AN - 3871615 AU - Yunus, M. B. AU - Masi, A. T. DA - Feb DO - 10.1002/art.1780280205 DP - NLM ET - 1985/02/01 IS - 2 KW - Absenteeism Adolescent Age Factors Antibodies, Antinuclear/analysis Autoantibodies/immunology Bone and Bones/diagnostic imaging Child Circadian Rhythm Disability Evaluation Female Fibromyalgia/physiopathology Follow-Up Studies Humans Male Muscular Diseases/*physiopathology Pain Radionuclide Imaging Syndrome LA - eng N1 - Yunus, M B Masi, A T AM-25663/AM/NIADDK NIH HHS/United States Journal Article Research Support, U.S. Gov't, P.H.S. United States Arthritis Rheum. 1985 Feb;28(2):138-45. doi: 10.1002/art.1780280205. PY - 1985 SN - 0004-3591 (Print) 0004-3591 SP - 138-45 ST - Juvenile primary fibromyalgia syndrome. A clinical study of thirty-three patients and matched normal controls T2 - Arthritis Rheum TI - Juvenile primary fibromyalgia syndrome. A clinical study of thirty-three patients and matched normal controls VL - 28 ID - 3370 ER - TY - JOUR AB - Background: We studied the epidemiology of functional gastrointestinal disorders (FGIDs) in school-aged Salvadoran children using standardized diagnostic criteria. Aims: To determine the prevalence of FGIDs in school-aged children in El Salvador. Material and methods: A total of 395 children participated in the study (one public school and one private school). School children completed the Spanish version of the Questionnaire on Pediatric Gastrointestinal Symptoms-Rome III (QPGS-III), an age-appropriate and previously validated instrument for diagnosing FGIDs according to the Rome III criteria. Sociodemographic (age, sex, type of school) and familial (family structure and size, family history of gastrointestinal disorders) data were obtained. Results: The mean age of the sample was 11.8 years +/- 1.6 SD (median 10, range 8-15) and 59% of the participants were female. Eighty-one children met the diagnostic criteria for a FG ID (20%). Defecation disorders were the most common group of FGIDs. Functional constipation was diagnosed in 10% of the children and 9.25% were diagnosed with abdominal pain-related FGIDs (most commonly IBS, 3.75%). IBS overlapped with functional dyspepsia in 11% of the cases. Children with FGIDs frequently reported nausea. Children attending private school and older children had significantly more FGIDs than children in public school and younger children. Conclusions: FGIDs are common in school-aged Salvadoran children. (C) 2015 Asociacion Mexicana de Gastroenterologia. Published by Masson Doyma Mexico S.A. AN - WOS:000437268900004 AU - Zablah, R. AU - Velasco-Benitez, C. A. AU - Merlos, I. AU - Bonilla, S. AU - Saps, M. DA - Jul-Sep DO - 10.1016/j.rgmx.2015.03.008 IS - 3 N1 - Zablah, R. Velasco-Benitez, C. A. Merlos, I. Bonilla, S. Saps, M. Zablah, Roberto/AAM-3835-2020 Zablah, Roberto/0000-0003-2799-2225; Velasco-Benitez, Carlos A/0000-0001-5647-3024; Velasco-Benitez, Carlos Alberto/0000-0002-4062-5326 PY - 2015 SN - 0375-0906 SP - 186-191 ST - Prevalence of functional gastrointestinal disorders in school-aged children in El Salvador T2 - Revista De Gastroenterologia De Mexico TI - Prevalence of functional gastrointestinal disorders in school-aged children in El Salvador UR - ://WOS:000437268900004 VL - 80 ID - 2230 ER - TY - JOUR AB - The purpose of the study was to assess the association of bullying and being bullied with indicators of subjective health and problem behaviors among schoolchildren aged 11-15 years. Material and methods. The data of the anonymous survey of 5645 filth-, seventh-, and ninth-grade students (aged 11, 13, and 15 years, respectively), conducted in the spring of 2002, were analyzed. The students completed the World Health Organization's Health Behavior in School-aged Children questionnaire that included self-report of involvement in bullying and being bullied by others as well as subjective health and well-being estimates, health complains (headache, stomachache, back pain, anxiety, etc.), and problem behaviors (smoking, alcohol and drug use, suicidal ideation). The response rate was 95%. Results. More than half (52.3%) of students were involved in bullying process at least two times per month: 17.9% were involved as bullies ("victims"), 18.3% were bullied ("aggressors"), and 16.1% bullied others and were bullied themselves. A significant association between experiencing bullying and adverse health outcomes was found. Perpetrating bullying increased the odds of smoking, alcohol and drug use. Perpetrating and/or experiencing bullying increased the risk of high suicidal ideation that had cumulative effect. The established associations varied between genders and groups of students defined as "victims," "aggressors," and "victims/aggressors." Conclusions. In Lithuania, school bullying is extremely prevalent and is associated with health disorders, poorer well-being, and problem behavior of schoolchildren. Urgent antibullying efforts, including both research and preventive measures, are needed in order to deal with this social phenomenon. AN - WOS:000255049100009 AU - Zaborskis, A. AU - Vareikiene, I. DO - 10.3390/medicina44030030 IS - 3 N1 - Zaborskis, Apolinaras Vareikiene, Inga 1648-9144 PY - 2008 SN - 1010-660X SP - 232-239 ST - School bullying and its association with health and lifestyle among schoolchildren T2 - Medicina-Lithuania TI - School bullying and its association with health and lifestyle among schoolchildren UR - ://WOS:000255049100009 VL - 44 ID - 2670 ER - TY - JOUR AB - Chronic pain is frequently experienced in adolescents; it affects functionality and requires interventions to decrease the impairments caused by pain. Cognitive behavioral therapy (CBT) has been analyzed in numerous studies that evaluated its effects on reducing the different types of chronic pain in children and adolescents. Interestingly, the outcome of CBT was initially focused on pain intensity, but, because there is no correspondence between children's pain intensity and level of disability, the ability to participate in school and social and recreational activities have been the primary focus of recent studies. There are innovative methods of CBT (such as the third generation of CBT) with and without the use of technology that facilitates the availability of this psychological treatment to adolescents with chronic pain, optimizing its accessibility and comprehensiveness, and maintaining its effectiveness. In the future, specific types of CBT could be specific to the diagnosis of chronic pain in the adolescent, sociodemographics, and other unique features. Parents of children with chronic pain are usually included in these programs, either as coaches in the intervention or as recipients of psychological therapies (including CBT) to optimize benefits. CBT has no adverse effect on chronic pain in adolescents, and there is no literature that makes reference to the effectiveness of CBT in preventing chronic pain in adolescents. A review of the role of CBT in chronic pain in adolescents via a PubMed database search was performed to identify the role of CBT in the management of chronic pain in adolescents. AN - WOS:000323594500010 AU - Zagustin, T. K. DA - Aug DO - 10.1016/j.pmrj.2013.05.009 IS - 8 N1 - Zagustin, Tamara K. 1934-1563 PY - 2013 SN - 1934-1482 SP - 697-704 ST - The Role of Cognitive Behavioral Therapy for Chronic Pain in Adolescents T2 - Pm&R TI - The Role of Cognitive Behavioral Therapy for Chronic Pain in Adolescents UR - ://WOS:000323594500010 VL - 5 ID - 2358 ER - TY - JOUR AB - Pain is a major health problem among U.S. adults. Surprisingly little, however, is known about educational disparities in pain, especially among the nonelderly. In this study, we analyze disparities in pain across levels of educational attainment. Using data from the 2010 to 2017 National Health Interview Survey among adults aged 30 to 49 (N = 74,051), we estimate logistic regression models of pain prevalence using a dichotomous summary pain index and its 5 constituent pain sites (low back, joint, neck, headache/migraine, and facial/jaw). We find a significant and steep pain gradient: greater levels of educational attainment are associated with less pain, with 2 important exceptions. First, adults with a high-school equivalency diploma (GED) and those with "some college" have significantly higher pain levels than high school graduates despite having an equivalent or higher attainment, respectively. Second, the education-pain gradient is absent for Hispanic adults. After taking into account important covariates including employment, economic resources, health behaviors, physical health conditions, and psychological wellbeing, educational disparities in pain are no longer statistically significant except for the GED and "some college" categories, which still show significantly higher pain levels than high school graduates. We thus document the overall education-pain gradient in most younger U.S. adult populations, and identify groups where pain is higher than expected (certain educational categories) or lower than expected (eg, less-educated Hispanics). Understanding the causes of these anomalous findings could clarify factors shaping pain prevalence and disparities therein. PERSPECTIVE: Over 50% of U.S. adults age 30 to 49 report pain. Overall, more educated Americans report substantially less pain than the less educated. However, adults with a GED and "some college" report more pain than other groups. Understanding the causes could help illuminate the mechanisms through which social factors influence pain. AD - Department of Sociology, University of Western Ontario, London, Canada. Electronic address: anna.zajacova@uwo.ca. Department of Sociology and Institute of Behavioral Science, University of Colorado Boulder. Department of Sociology, University of Wisconsin Madison. Department of Sociology, University at Buffalo, State University of New York. AN - 32574784 AU - Zajacova, A. AU - Rogers, R. G. AU - Grodsky, E. AU - Grol-Prokopczyk, H. C2 - PMC7722114 C6 - NIHMS1619384 DA - Nov-Dec DO - 10.1016/j.jpain.2020.03.005 DP - NLM ET - 2020/06/24 IS - 11-12 KW - *Educational attainment *National Health Interview Survey *U.S. adults *disparities *pain *population LA - eng N1 - 1528-8447 Zajacova, Anna Rogers, Richard G Grodsky, Eric Grol-Prokopczyk, Hanna P2C HD047873/HD/NICHD NIH HHS/United States P30 AG017266/AG/NIA NIH HHS/United States R03 AG050130/AG/NIA NIH HHS/United States Journal Article Research Support, N.I.H., Extramural J Pain. 2020 Nov-Dec;21(11-12):1270-1280. doi: 10.1016/j.jpain.2020.03.005. Epub 2020 Jun 20. PY - 2020 SN - 1526-5900 (Print) 1526-5900 SP - 1270-1280 ST - The Relationship Between Education and Pain Among Adults Aged 30-49 in the United States T2 - J Pain TI - The Relationship Between Education and Pain Among Adults Aged 30-49 in the United States VL - 21 ID - 4187 ER - TY - JOUR AB - While the relationship between education and general health has been firmly established in the literature, surprisingly little research has analyzed individual components of the global health judgments, such as chronic conditions or pain. We present a systematic account of the health gradient for multiple health outcomes by detailed educational categories among U.S. working-age adults. Using the 1997-2010 National Health Interview Surveys (N = 204,764), we analyze individual health outcomes ranging from cardiovascular disease to vision problems with a series of logistic regression models. The results at the presecondary and baccalaureate levels are consistent with the health gradient. An unexpected finding occurs among adults with some college but no degree, and those with technical/vocational associate degrees: these groups report more pain and a higher prevalence of a broad range of conditions than high school graduates who never attended college. We discuss several explanations for the observed patterns. The findings challenge the broadly accepted educational gradient in health: additionally, the lower postsecondary groups comprise a quarter of American adults. jointly, there is a clear research and policy impetus to understand the source of this 'glitch' in the health gradient. (C) 2012 Elsevier Ltd. All rights reserved. AN - WOS:000310385200012 AU - Zajacova, A. AU - Rogers, R. G. AU - Johnson-Lawrence, V. DA - Dec DO - 10.1016/j.socscimed.2012.07.036 IS - 11 N1 - Zajacova, Anna Rogers, Richard G. Johnson-Lawrence, Vicki Johnson-Lawrence, Vicki/G-8539-2014 Johnson-Lawrence, Vicki/0000-0002-8582-3916 PY - 2012 SN - 0277-9536 SP - 2007-2012 ST - Glitch in the gradient: Additional education does not uniformly equal better health T2 - Social Science & Medicine TI - Glitch in the gradient: Additional education does not uniformly equal better health UR - ://WOS:000310385200012 VL - 75 ID - 2409 ER - TY - JOUR AB - Recurrent abdominal pain (RAP) syndrome is described by Apley 40 years ago. The definition of condition, still generally accepted, is at least three episodes of abdominal pain over a period of three months, with pain of intensity which affects the behaviour of the child. The prevalence of condition among school children is 10-15%. Apley's classic studies demonstrated organic disease in only 10% of the children. Apley's conclusions have dominated pediatric writing through present era. In recent years, however, a number of reports have appeared in the medical literature that have suggested that careful investigation of children with RAP may reveal previously unsuspected functional or morphologic abnormalities of the gastrointestinal tract. These have included reports of peptic disease and Helicobacter Pylori infection, abnormal antro-duodenal motility, lactase malabsorption, gastro-esophageal reflux. Nevertheless these abnormalities cannot be correlated always with specific complaints. Therefore pathogenetic background is not clarified. Despite greater understanding of these disorders the enigme remains. There is a need for controlled studies in non selected patients. AD - Dipartimento di Pediatria, Università di Padova, Italia. AN - 8685027 AU - Zancan, L. AU - Guariso, G. AU - Gobber, D. DA - Jan-Feb DP - NLM ET - 1996/01/01 IS - 1 KW - Abdominal Pain/etiology/*physiopathology Adolescent Age Factors Child Female Gastroesophageal Reflux/complications Helicobacter Infections/complications Humans Malabsorption Syndromes/complications Male Recurrence Syndrome LA - ita N1 - Zancan, L Guariso, G Gobber, D English Abstract Journal Article Italy Pediatr Med Chir. 1996 Jan-Feb;18(1):65-6. OP - La sindrome del dolore addominale ricorrente 40 anni dopo: revisione critica. PY - 1996 SN - 0391-5387 (Print) 0391-5387 SP - 65-6 ST - [Abdominal pain syndrome recurring after 40 years: critical revision] T2 - Pediatr Med Chir TI - [Abdominal pain syndrome recurring after 40 years: critical revision] VL - 18 ID - 3440 ER - TY - JOUR AB - BACKGROUND: Irritable bowel syndrome (IBS) is a common chronic medical condition, in both children and adults. Despite the availability of effective (non)pharmacological treatments, symptoms persist in a significant amount of patients with IBS. Faecal microbiota transplantation (FMT) may be an effective alternative treatment in adolescents with refractory IBS through manipulation of the intestinal microbiota. METHODS AND ANALYSIS: This randomised, placebo-controlled single-centre pilot study will assess feasibility and efficacy of FMT in 30 adolescents (16-21 years) with refractory IBS. Patients will be randomly allocated (1:1) to receive two allogeneic (healthy donor) or two autologous (own) faecal infusions at baseline and after 6 weeks. Primary outcomes will assess feasibility, including patient and donor recruitment, adherence and incidence rates of adverse events. To evaluate clinical efficacy, secondary outcomes will include the proportion of patients with at least >50% reduction of their abdominal pain intensity and frequency 12 weeks after the first FMT, and after 6-month and 12-month follow-up. Other outcomes comprise changes in faecal gut microbiota composition, quality of life, depression and anxiety, school or work absenteeism and adequate relief, measured directly after FMTs and after 6 and 12 months of follow-up. DISCUSSION: This randomised controlled trial will investigate the feasibility and effectiveness of repetitive FMTs in adolescents with refractory IBS. ETHICS AND DISSEMINATION: The study is approved by the Medical Research Ethics Committees AMC (MEC-AMC) in the Netherlands. TRIAL REGISTRATION NUMBER: NCT03074227. AD - Paediatric Gastroenterology, Emma Childrens Hospital AMC, Amsterdam, North Holland, The Netherlands. Amsterdam UMC, University of Amsterdam, Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam, the Netherlands. Amsterdam University Medical Centers, Location Academic Medical Center/Emma Children's Hospital, Amsterdam Reproduction & Development Research Institute, Amsterdam, the Netherlands. Department of Paediatrics, Sint Antonius Hospital, Nieuwegein, The Netherlands. Department of Internal Medicine, Amsterdam UMC-Locatie AMC, Amsterdam, North Holland, Netherlands. Paediatric Gastroenterology and Nutrition, Emma Kinderziekenhuis AMC, Amsterdam, North Holland, Netherlands. AN - 32864480 AU - Zeevenhooven, J. AU - de Bruijn, C. M. A. AU - Vlieger, A. AU - Nieuwdorp, M. AU - Benninga, M. A. C2 - PMC7443263 DO - 10.1136/bmjpo-2020-000689 DP - NLM ET - 2020/08/31 IS - 1 KW - gastroenterology Kaleido BioSciences however, none of these are directly related to the current manuscript. LA - eng N1 - 2399-9772 Zeevenhooven, Judith de Bruijn, Clara Marieke Andrea Orcid: 0000-0001-6259-9918 Vlieger, Arine Nieuwdorp, Max Benninga, Marc Alexander Journal Article BMJ Paediatr Open. 2020 Aug 20;4(1):e000689. doi: 10.1136/bmjpo-2020-000689. eCollection 2020. PY - 2020 SN - 2399-9772 SP - e000689 ST - Protocol for a pilot randomised, double-blind, placebo-controlled trial for assessing the feasibility and efficacy of faecal microbiota transplantation in adolescents with refractory irritable bowel syndrome: FAIS Trial T2 - BMJ Paediatr Open TI - Protocol for a pilot randomised, double-blind, placebo-controlled trial for assessing the feasibility and efficacy of faecal microbiota transplantation in adolescents with refractory irritable bowel syndrome: FAIS Trial VL - 4 ID - 4141 ER - TY - JOUR AB - Benign Joint Hypermobility Syndrome (BJHS) is a major source of morbidity in children and adolescents. Due to fatigue and pain, activities of daily living may be limited. Aim of the work: To investigate the relationship between fatigue and health related quality of life in adolescents with BJHS. Patients and methods: Thirty adolescents with BJHS and 30 controls were enrolled in the study. All participants were subjected to clinical and laboratory assessment to exclude other causes of fatigue. All were requested to complete self assessment Pediatric Quality of Life (PedsQL) and multidimensional fatigue scale questionnaires. Pain was assessed by Visual Analogue Scale (VAS). Results: Compared to healthy adolescents, patients with BJHS had a significant lower total score for PedsQL scale (52.56 +/- 8.40 and 87.63 +/- 4.68 for patients and controls respectively, p < 0.001) and a significant lower total score for multidimensional fatigue scale (66.09 +/- 13.05 and 91.32 +/- 3.97 for patients and controls respectively, p < 0.001). General and cognitive fatigue that accompanied BJHS, were the only significant predictors of lower health related quality of life in patients' group. Among patients with BJHS; general fatigue was a significant predictor for emotional and social function impairment, while cognitive fatigue was a significant predictor for school function reduction. Total multidimensional fatigue scale score, general and cognitive fatigue were predictors of physical function impairment in patients and controls. VAS was highly correlated to PedsQL (r = -0.88, p = < 0.001) and multidimensional fatigue (r = -0.99, p = < 0.001) scales. Conclusion: This study highlights the importance of fatigue as a significant predictor of poor health related quality of life in adolescents with BJHS. (C) 2012 Egyptian Society for Joint Diseases and Arthritis. Production and hosting by Elsevier B.V. Open access under CC BY-NC-ND license. AN - WOS:000408959600006 AU - Zekry, A. AU - Ahmed, M. A. AU - Elwahid, Haea DA - Apr DO - 10.1016/j.ejr.2012.12.002 IS - 2 N1 - Zekry, Osama Ali Ahmed, Manal Ali Elwahid, Hassan Ali Elsayed Abd Zekry, Abdelhalim/AAJ-3544-2021 2090-2433 PY - 2013 SN - 1110-1164 SP - 77-85 ST - The impact of fatigue on health related quality of life in adolescents with benign joint hypermobility syndrome T2 - Egyptian Rheumatologist TI - The impact of fatigue on health related quality of life in adolescents with benign joint hypermobility syndrome UR - ://WOS:000408959600006 VL - 35 ID - 2378 ER - TY - JOUR AB - ObjectivesAnxiety modulates symptom perception in adults following concussion, prolonging the time to full recovery. The authors sought to determine whether parental anxiety was associated with persistent postconcussive symptoms (PCS) in their children following concussion. MethodsA prospective observational cohort with 98 children aged 5 to 17years following concussion participated from a tertiary pediatric emergency department (ED). The main exposure was parental anxiety at the time of acute presentation following pediatric concussion, measured using the self-administered, validated Spielberger State-Trait Anxiety Inventory-State Anxiety Scale (STAI-S). The primary outcome measured was presence of PCS in the child at 1month, per the validated Post-Concussive Symptom Inventory (PCSI). Secondary outcome measures included parental anxiety score over time, school absenteeism, and return to sports. Data were collected during the initial ED visit and at 3-day, 7-day, 2-week, 1-month, and 3-month follow-ups. ResultsOf 98 children enrolled, 27% (95% confidence interval [CI]=19% to 36%) developed PCS at 1month. No significant associations were detected between parental anxiety at the index visits and the number of previous pediatric concussions (p=0.73), sex (p=0.61), loss of consciousness (p=0.43), history of migraines (p=0.31), or history of anxiety diagnosed in the patients (p=0.09). A significant association was noted between patient diagnosis of attention deficit hyperactivity disorder (ADHD) and parental anxiety at the index visits (p=0.001). Parental anxiety at acute presentation was not associated with children's prolonged symptoms at 1month (p=0.63). Parental anxiety remained elevated in parents whose children had prolonged symptoms compared to those parents whose children's symptoms resolved (median=30, interquartile range [IQR]=22 to 44; and median=21, IQR=20 to 25, respectively; p<0.001). Initial parental anxiety presentation was not associated with school absenteeism (p=0.23) or not returning to sport or gym class (p=0.89). There were no significant effects involving ADHD alone (p=0.44) or together with baseline parental anxiety (p=0.36 for ADHD and p=0.55 for anxiety) using logistic regression analysis to examine potential predictive effects of child's ADHD combined with parental anxiety at the index visit on persistent symptoms at 1month. ConclusionsParental anxiety at time of acute presentation does not appear to be associated with prolongation of postconcussive symptoms in their children. However, parents of persistently symptomatic children remain significantly more anxious than those whose children's symptoms have resolved. Future research should attempt to reduce the familial burden of concussion through expectation management strategies. AN - WOS:000326023700010 AU - Zemek, R. AU - Clarkin, C. AU - Farion, K. J. AU - Vassilyadi, M. AU - Anderson, P. AU - Irish, B. AU - Goulet, K. AU - Barrowman, N. AU - Osmond, M. H. DA - Oct DO - 10.1111/acem.12220 IS - 10 N1 - Zemek, Roger Clarkin, Chantalle Farion, Ken J. Vassilyadi, Michael Anderson, Peter Irish, Brendan Goulet, Kristian Barrowman, Nick Osmond, Martin H. Barrowman, Nick/AAL-3166-2020; Zemek, Roger/H-1039-2018; Meijer, Anna/K-5118-2016 Barrowman, Nick/0000-0002-4704-9595; Osmond, Martin/0000-0001-8275-8381 1553-2712 PY - 2013 SN - 1069-6563 SP - 1041-1049 ST - Parental Anxiety at Initial Acute Presentation Is Not Associated With Prolonged Symptoms Following Pediatric Concussion T2 - Academic Emergency Medicine TI - Parental Anxiety at Initial Acute Presentation Is Not Associated With Prolonged Symptoms Following Pediatric Concussion UR - ://WOS:000326023700010 VL - 20 ID - 2343 ER - TY - JOUR AB - Background To date only few studies have addressed the level of intelligence of children and adolescents with chronic pain. The few currently available studies suggest a cognitive performance of pediatric pain patients in the average range (IQ 85-115); however, only little is known about the relationship between pain characteristics and cognitive skills. Objective The aim of the study was to retrospectively examine the intelligence scores of severely impaired pediatric chronic pain patients to improve the knowledge about the association of pain and cognitive performance and to create a basis for further prospective studies. Material and methods In the exploratory evaluation data from N= 180 children and adolescents who were treated as inpatients at the German Pediatric Pain Center in Datteln in 2016 were included. Due to the standardization of the IQ scores a comparison within the sample was possible as well as a comparison to the norm sample. Results The intelligence level of severely impaired pediatric pain patients fell within the normal range (M= 99.32; SD= 14.13). Neither the main pain location nor the emotional variables or pain parameters (e.g. pain intensity) had a significant association with the IQ scores. Compared to the norm sample, pediatric pain patients had a higher processing speed. Intraindividual comparisons showed a significantly lower verbal IQ than performance IQ and a lower verbal comprehension compared to perceptual organization and processing speed. Moreover, there was a negative association between pain intensity, the verbal IQ and verbal comprehension. Conclusion The results support the assumption that the intellectual performance of pediatric pain patients lies within the average range; however, the results indicate a limited competence in verbal abstraction and expressiveness of pediatric pain patients, which are negatively related to pain intensity. Further studies to examine causal relationships are needed. AN - WOS:000478886200004 AU - Zepp, B. AU - Grothus, S. AU - Zernikow, B. AU - Wager, J. DA - Aug DO - 10.1007/s00482-019-0382-2 IS - 4 N1 - Zepp, Britta Grothus, Susanne Zernikow, Boris Wager, Julia Wager, Julia/0000-0003-4493-6356 1432-2129 PY - 2019 SN - 0932-433X SP - 303-311 ST - The association between intelligence and pain in children and adolescents with severely impairing chronic pain A retrospective analysis T2 - Schmerz TI - The association between intelligence and pain in children and adolescents with severely impairing chronic pain A retrospective analysis UR - ://WOS:000478886200004 VL - 33 ID - 1893 ER - TY - JOUR AB - OBJECTIVE: To explore the prevalence and characteristics of chronic headache in children and adolescents in Shanghai and to collect messages concerning the impact and compliance of medication for migraine. METHODS: A population-based questionnaire study was conducted among subjects 6 - 15 years of age sampled from primary and junior high schools in Shanghai and the subjects were followed up. RESULTS: (1) The prevalence: 8701 (88.6%) out of 9857 pupils responded to the questionnaire; 17% of the respondents had headache and in 86.4% of them the reason of headache was unknown. The prevalence of chronic headache in Shanghai children and adolescents was 7.8%, there was no significant difference between both genders (chi(2) = 0.010, P > 0.05). (2) The prevalence of chronic headache increased with age, the incidence was higher in boys before 12 years of age, while higher in girls after 12 years of age. (3) Characteristics of chronic headache: the proportion of unilateral, bilateral and headache of unknown site was similar; in most of the cases headache was localized in the temple (35.2%) and forehead region (25.6%), the duration of headache was short, always accompanied by gastrointestinal symptoms. Half of the patients reported that the headache had affected their study and daily life. (4) The status of using health care facilities: 24% of the students sought medical assistance during their headache episodes and among them only 30.9% took medicine. (5) Over-fatigue (51.4%), followed by insufficient sleep (40.4%), emotional changes (38.5%) were the main aggravating factors. The headache was also associated with positive family history and stress in studying. CONCLUSIONS: Headache is a common complaints of children, affecting the patients' study and daily life. But many patients with headache were not treated properly, therefore, the medical and educational sectors and the society should pay more attention to this problem. AD - Department of Neurology, Children's Hospital, Fudan University, Shanghai 200032, China. AN - 17706062 AU - Zhang, L. M. AU - Zhou, S. Z. AU - Chai, Y. M. AU - Yang, J. D. AU - Xue, J. AU - Liang, J. DA - Apr DP - NLM ET - 2007/08/21 IS - 4 KW - Adolescent Child China/epidemiology Female Headache Disorders/*epidemiology Humans Male Prevalence *Surveys and Questionnaires LA - chi N1 - Zhang, Lin-Mei Zhou, Shui-Zhen Chai, Yi-Ming Yang, Jiang-Ding Xue, Jing Liang, Ji English Abstract Journal Article China Zhonghua Er Ke Za Zhi. 2007 Apr;45(4):262-6. PY - 2007 SN - 0578-1310 (Print) 0578-1310 SP - 262-6 ST - [Prevalence of chronic headache in Shanghai children and adolescents: a questionnaire-based study] T2 - Zhonghua Er Ke Za Zhi TI - [Prevalence of chronic headache in Shanghai children and adolescents: a questionnaire-based study] VL - 45 ID - 3128 ER - TY - JOUR AB - Introduction Pre-emptive scalp infiltration with local anaesthetics is the simplest and most effective method to prevent postoperative incisional pain. However, local infiltration of an anaesthetic only provides relatively short-term pain relief. Methylprednisolone (MP) treatment, administered as an adjuvant at the wound site, has been shown to provide satisfactory pain management after lumbar laminectomy. However, there is no evidence regarding the efficacy of MP infiltration for the relief of postoperative pain after craniotomy. Currently, postoperative pain after craniotomy in children is undertreated. Therefore, we aim to investigate whether pre-emptive scalp infiltration with ropivacaine (RP) plus MP is superior to RP alone to improve postoperative pain after craniotomy in children. Methods and analysis The RP/MP versus RP trial is a prospective, single-centre, randomised, parallel-group study of 100 children aged 8-18 years undergoing intracranial surgery. Participants will be randomly allocated to receive pre-emptive scalp infiltration with either RP plus MP or RP alone. The primary outcome will be the cumulative fentanyl dose administered by patient-controlled intravenous analgesia within 24 hours postoperatively. The secondary outcomes will include postoperative Numerical Rating Scale scores, pain control satisfaction scores, length of stay and adverse events. Data will be analysed by the intention-to-treat principle. Ethical approval and dissemination The study protocol has been approved by the Institutional Review Board of Beijing Tiantan Hospital Affiliated to Capital Medical University (Approval Number: KY 2018-066-02). The results will be disseminated in international academic meetings and published in peer-reviewed journals. AN - WOS:000562117100146 AU - Zhao, C. M. AU - Jia, Y. T. AU - Jia, Z. P. AU - Xiao, X. AU - Luo, F. C7 - e027864 DA - Jun DO - 10.1136/bmjopen-2018-027864 IS - 6 N1 - Zhao, Chunmei Jia, Yitong Jia, Zipu Xiao, Xiong Luo, Fang PY - 2019 SN - 2044-6055 ST - Pre-emptive scalp infiltration with ropivacaine plus methylprednisolone versus ropivacaine alone for relief of postoperative pain after craniotomy in children (RP/MP vs RP): a study protocol for a randomised controlled trial T2 - Bmj Open TI - Pre-emptive scalp infiltration with ropivacaine plus methylprednisolone versus ropivacaine alone for relief of postoperative pain after craniotomy in children (RP/MP vs RP): a study protocol for a randomised controlled trial UR - ://WOS:000562117100146 VL - 9 ID - 1917 ER - TY - JOUR AB - BACKGROUND: Stress is a common contributing factor for irritable bowel syndrome (IBS). This study was to evaluate the efficacy of the centralized health education program in improving the quality of life (QOL) of middle school students with IBS who experienced the Wenchuan earthquake on May 12, 2008. METHODS: A multi-center, randomized and open evaluation study design was adopted. A total of 584 students who met the Rome III criteria for IBS in four middle schools were identified. Of these students, 29 were excluded for various reasons, and the remaining 555 students were randomly assigned to either the health education group (n = 277) or the control group (n = 278, received no health education). De-identified data were collected via the IBS quality of life (IBS-QOL) questionnaire and abdominal pain was assessed during the 5-year follow-up survey. RESULTS: The IBS-QOL mean total score was comparable at baseline between no-education group and education group no matter in quake-unaffected areas or quake-affected areas (52.27 vs 51.43, t = 1.15, P > 0.05; 51.02 vs 50.64, t = 1.98, P > 0.05). During the 5-year study period, 84 students opted out during follow-up. After 5 years, a significant difference of the IBS-QOL mean total score was observed between the no-education group and education group in quake-unaffected areas (80.53 vs 93.67, t = - 55.45, P < 0.01), which was also observed in quake-affected areas (64.23 vs 93.80, t = - 188.10, P < 0.01). In addition, there was a reciprocal action between factor 1(health education or not) and factor 2(affected by the earthquake or not) regarding IBS-QOL for dysphoria(Q1), interference with activity(Q2), food avoidance(Q5) and relationships(Q8)(P < 0.001) at year 1, 3 and 5. In all students, abdominal pain scores gradually reduced from baseline in each subgroup over 5 years (P < 0.001).The improvement was greater in the education group than in the control group no matter in quake-unaffected area and in quake-affected areas(P < 0.001). There was a reciprocal action between factor 1(health education or not) and factor 2(duration of follow-up) regarding the mean abdominal pain symptom score irrespective of quake-unaffected or quake-affected areas (P = 0.029 and P < 0.001). CONCLUSION: The health education program improved quality of life and abdominal pain in middle school IBS students in Wenchuan quake-affected areas. AD - Department of Gastroenterology, The First People's Hospital of Longquanyi District, Chengdu & West China Longquan Hospital Sichuan University, Sichuan Province, Chengdu, 610100, China. zsc333-007@163.com. Department of Gastroenterology, The First People's Hospital of Longquanyi District, Chengdu & West China Longquan Hospital Sichuan University, Sichuan Province, Chengdu, 610100, China. Department of Gastroenterology, West China Hospital, Sichuan University, Sichuan Province, Chengdu, 610041, China. West China School of Public Health, Sichuan University, Chengdu, 610041, Sichuan Province, China. Qingchuan Middle School, Qingchuan County, 628100, Sichuan Province, China. Wenchuan First Middle School, Wenchuan County, 638100, Sichuan Province, China. Tongji Middle School, Pengzhou City, 611900, Sichuan Province, China. Longquan District of Chengdu Maternity and Child Health Care Hospital, Sichuan Province, Chengdu, 610100, China. AN - 30053840 AU - Zheng, S. C. AU - Gong, H. AU - Wang, Y. P. AU - Zhang, Q. AU - Wang, L. L. AU - Liao, X. F. AU - He, D. W. AU - Wu, J. C2 - PMC6062936 DA - Jul 27 DO - 10.1186/s12876-018-0845-4 DP - NLM ET - 2018/07/29 IS - 1 KW - Abdominal Pain/psychology Adolescent China *Earthquakes Female Follow-Up Studies *Health Education Humans Irritable Bowel Syndrome/*psychology Male *Quality of Life *Stress, Psychological Earthquake Health education Irritable bowel syndrome Middle school students Quality of life The centralized health education program Institutional Review Board of The First People’s Hospital of Longquanyi District, Chengdu/ West China Longquan Hospital Sichuan University. Written informed consent was obtained from the participants’ parents prior to the study. CONSENT FOR PUBLICATION: Not applicable. COMPETING INTERESTS: The authors declare that they have no competing interests. PUBLISHER’S NOTE: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. LA - eng N1 - 1471-230x Zheng, Shi-Cheng Gong, Hui Wang, Yi-Ping Zhang, Qiang Wang, Li-Li Liao, Xue-Fen He, Dai-Wen Wu, Jing 090103/the Science Research Project of the Sichuan Provincial Department of Health,China/ Journal Article Multicenter Study Randomized Controlled Trial BMC Gastroenterol. 2018 Jul 27;18(1):119. doi: 10.1186/s12876-018-0845-4. PY - 2018 SN - 1471-230x SP - 119 ST - Health education program improves QOL in students with irritable bowel syndrome after the Wenchuan earthquake: a five-year multi-center study T2 - BMC Gastroenterol TI - Health education program improves QOL in students with irritable bowel syndrome after the Wenchuan earthquake: a five-year multi-center study VL - 18 ID - 4021 ER - TY - JOUR AB - PURPOSE: This study aimed to determine whether functional gastrointestinal disorders are more common among adolescents with self-reported poor sleep. METHODS: Junior middle school and senior high school students (n = 1,362) were recruited from schools in Shanghai. Students completed two questionnaires: the questionnaire for irritable bowel syndrome (IBS) in adolescents and the Pittsburgh Sleep Quality Index. RESULTS: The prevalence of poor sleep was 34.29% [95% confidence interval (CI) = 31.77-36.81] and there was no significant difference between genders (P = 0.991). The tendency towards poor sleep increased with age, with age group yielding a significant effect (P = 0.001). In junior middle school and senior high school students, the propensity towards poor sleep was 30.10% (95% CI = 27.08-33.12%) and 42.11% (95% CI = 37.67-46.55%), respectively. Among students with poor sleep, the prevalence of IBS was 19.70% (95% CI = 16.09-23.31). After adjusting for age, sex, night pain, and psychological factors, IBS was significantly more common in students with poor sleep (odds ratio = 1.92; 95% CI = 1.07-2.58). CONCLUSION: We conclude that IBS is prevalent in students with poor sleep. Poor sleep was independently associated with IBS among adolescents in Shanghai China. AD - Department of Gastroenterology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200092, China. hq.zhou@yahoo.com.cn AN - 22203339 AU - Zhou, H. Q. AU - Yao, M. AU - Chen, G. Y. AU - Ding, X. D. AU - Chen, Y. P. AU - Li, D. G. DA - Dec DO - 10.1007/s11325-011-0635-5 DP - NLM ET - 2011/12/29 IS - 4 KW - Adolescent China Constipation/diagnosis/epidemiology Cross-Sectional Studies *Developing Countries Diarrhea/diagnosis/epidemiology Female Gastrointestinal Diseases/diagnosis/*epidemiology Health Surveys Humans Irritable Bowel Syndrome/diagnosis/epidemiology Male Quality of Life Risk Factors Sleep Deprivation/diagnosis/*epidemiology Sleep Initiation and Maintenance Disorders/diagnosis/*epidemiology Statistics as Topic LA - eng N1 - 1522-1709 Zhou, Hui-Qing Yao, Min Chen, Guang-Yu Ding, Xiao-Dong Chen, Yan-Ping Li, Ding-Guo Journal Article Germany Sleep Breath. 2012 Dec;16(4):1211-8. doi: 10.1007/s11325-011-0635-5. Epub 2011 Dec 22. PY - 2012 SN - 1520-9512 SP - 1211-8 ST - Functional gastrointestinal disorders among adolescents with poor sleep: a school-based study in Shanghai, China T2 - Sleep Breath TI - Functional gastrointestinal disorders among adolescents with poor sleep: a school-based study in Shanghai, China VL - 16 ID - 4050 ER - TY - JOUR AB - To determine the prevalence and risk factors of IBS in children 8-13 years of age in Suzhou city, a cross-sectional study was conducted on children in grades 1 through 6 in public elementary schools in three districts of Suzhou. A multistage stratified random-sampling survey was conducted in a primary investigation using standardized questionnaires. Rome II criteria were used to confirm IBS and their risk factors were analyzed. Of 8,000 questionnaires 7,472 responded satisfactorily for a response rate of 93.4%. IBSwas diagnosed in 10.81%. A decrease in the prevalence of IBS was significantly associated with advancing age and grade in school (trend test,P < 0.05). The prevalence of IBS in females was higher but not significantly different than males. The significant risk factors for IBS included young age (OR = 0.94), food allergy (OR = 1.53), gastroenteritis during childhood (OR = 1.29), eating fried food (OR = 1.62), anxiety (OR = 1.49), psychological insults in early childhood (OR = 1.47), and parental history of constipation (OR = 1.81; all P < 0.05). IBS prevalence of 10.81% in study population warrants preventive measures such as encouraging dietary changes, preventing gastroenteritis and childhood psychological insults. AN - WOS:000336295200001 AU - Zhu, X. P. AU - Chen, W. C. AU - Zhu, X. L. AU - Shen, Y. P. C7 - 198461 DO - 10.1155/2014/198461 N1 - Zhu, Xueping Chen, Weichang Zhu, Xiaoli Shen, Yueping Chen, Wei-Chang/0000-0001-8849-6204 1687-630x PY - 2014 SN - 1687-6121 ST - A Cross-Sectional Study of Risk Factors for Irritable Bowel Syndrome in Children 8-13 Years of Age in Suzhou, China T2 - Gastroenterology Research and Practice TI - A Cross-Sectional Study of Risk Factors for Irritable Bowel Syndrome in Children 8-13 Years of Age in Suzhou, China UR - ://WOS:000336295200001 VL - 2014 ID - 2324 ER - TY - JOUR AB - Purpose Victimization by peers is known to have a detrimental effect on emotional and educational adjustment. Yet, there is also a sparser research literature on the potential negative effects of peer victimization on physical health. Our purpose was to draw from meta-analyses and studies of peer victimization and physical health (including psychosomatic symptoms, sleep, and body weight) to highlight key findings and future directions in the area. We also briefly summarize research findings that associate peer victimization with stress physiology. Method Narrative research summary. Results Peer victimization is associated with poorer physical health among youth, including more somatic complaints (e.g., health concerns, pain) and disrupted sleep. Also, victimized youth are at more risk than other youth for increasing weight problems. These effects seem to be both immediate and long-term, with associations found into later adolescence and even adulthood. Conclusion Future directions for research are proposed that take a biopsychosocial perspective, by integrating the domains of physiology, mental health, and physical health, in order to test holistic models that better illuminate the negative effects of peer victimization. Additionally, future research should continue to address potential mechanisms, such as neurophysiological reactions and recovery from stressful events. AN - WOS:000472757500005 AU - Zimmer-Gembeck, M. J. AU - Duffy, A. L. AU - Stuart, J. C7 - e12162 DA - Jun DO - 10.1111/jabr.12162 IS - 2 N1 - Zimmer-Gembeck, Melanie J. Duffy, Amanda L. Stuart, Jaimee Duffy, Amanda/ABF-9509-2020; Stuart, Jaimee/B-5844-2018; Zimmer-Gembeck, Melanie/H-3031-2015 Duffy, Amanda/0000-0001-6241-8443; Stuart, Jaimee/0000-0002-4376-1913; Zimmer-Gembeck, Melanie/0000-0001-9100-010X 1751-9861 Si PY - 2019 SN - 1071-2089 ST - Let's get physical: Recent research on relations of adolescent peer victimization with psychosomatic symptoms, sleep, and body weight T2 - Journal of Applied Biobehavioral Research TI - Let's get physical: Recent research on relations of adolescent peer victimization with psychosomatic symptoms, sleep, and body weight UR - ://WOS:000472757500005 VL - 24 ID - 1911 ER - TY - JOUR AB - In the past the view has often been expressed that children are less sensitive to pain than adults as a result of the assumption that their nervous system is not as well developed. According to this theory, newborns were not supposed to feel pain at all, and for this reason minor surgery was often performed with inadequate anesthesia. Evidence in the more recent literature and the regular choice of "pain in children" as a topic for congresses exemplify the more and more widespread belief that children of all ages can feel pain and, relative to their developmental stage, suffer accordingly. However, there are significant differences in the way children experience and react to pain in comparison to adults, e.g., because of the difference in ability to evaluate acute or chronic pain cognitively. At birth, all human sensory organs have developed far enough to be full functional-as a result of the long gestational period, which is far longer than most other mammalian species. The results of animal experiments and observations in newborns have led to the conclusion that in humans and other mammals, the sensory pain system is fully developed at birth. Pain-related reactions can be seen in the motor, vegetative and endocrine pain parameters, and in the infant's crying. As the experience of pain increases, conditioned avoidance reactions can be noted, as can the child's experience of psychosomatic pain reinforcement by the care-givers, e.g., when a crying child in pain receives more attention from the persons around it. In pre-school children, the level of pain can be measured using appropriate instruments, as demonstrated in cases of chronic arthritis. As cognition develops further, the patient's own concept of health and sickness changes, as does the ability to express feelings of pain. In the pathogenesis of pain in children, the dominant types are nociceptor pain (e.g., as a result of trauma or infection) and pain resulting from malfunction (e.g., physical malposition, migraine), whereas nervous pain occurs less frequently. Pediatricians should pay particular attention to the treatment of acute and chronic pain in children. AD - Abteilung für Physiologie des Zentralnervensystems, II. Physiologisches Institut der Universität, Im Neuenheimer Feld 326, D-6900, Heidelberg. AN - 18415362 AU - Zimmermann, M. DA - Jun DO - 10.1007/bf02527482 DP - NLM ET - 1989/06/01 IS - 2 LA - ger N1 - Zimmermann, M English Abstract Journal Article Germany Schmerz. 1989 Jun;3(2):73-9. doi: 10.1007/BF02527482. OP - Neuro- und Psychophysiologie des Schmerzes bei Kindern. PY - 1989 SN - 0932-433X (Print) 0932-433x SP - 73-9 ST - [Neuro- and psychophysiology of pain in children.] T2 - Schmerz TI - [Neuro- and psychophysiology of pain in children.] VL - 3 ID - 4130 ER - TY - JOUR AB - Although controversial, opioid analgesics have been prescribed for patients with chronic facial pain. Based primarily on survey data and a few well-controlled clinical trials, long-term opioid treatment provides adequate pain reduction in 41% to 100% of patients with chronic nonmalignant pain. However, only 25% of chronic Facial pain patients reported adequate pain relief with chronic opioid treatment. Work, home, and school function are generally reestablished or maintained during chronic opioid treatment, but 25% to 38% of patients remain dysfunctional, and one study indicated that 20% of patients became dysfunctional during treatment. Chronic opioid treatment is associated with many transient side effects; constipation, dizziness, nausea, vomiting, itching, and fatigue have been reported in 5% to 42% of patients taking opioids over 1 year. Although survey studies suggest that the risks of addiction are low in typical patients, drug abuse rates up to 17.3% and prescription abuse rates up to 27.6% were reported within groups of chronic opioid users. Chronic opioid use induces analgesic tolerance and physical dependence, which may result in a serious abstinence syndrome in users and children born to users. Chronic opioid use also may induce harmful immune system changes, diminish cognitive and motor Function, and produce nociceptive hyperexcitability This article shows that the use of long-term opioids for chronic facial pain is not justified based on the available data. Despite these perceived problems, there is anecdotal evidence that chronic facial pain patients will respond positively to opioid analgesics. In our experience, the pain assessment scale and a modification of the World Health Organization's three-step analgesic ladder, which prescribes nonopioid analgesics, can be the starting point for the successful management of chronic facial pain. AN - WOS:000075669400016 AU - Zuniga, J. R. DA - Sep DO - 10.1016/s0278-2391(98)90260-9 IS - 9 N1 - Zuniga, JR zuniga, john/0000-0002-8602-2811 PY - 1998 SN - 0278-2391 SP - 1075-1080 ST - The use of nonopioid drugs in management of chronic orofacial pain T2 - Journal of Oral and Maxillofacial Surgery TI - The use of nonopioid drugs in management of chronic orofacial pain UR - ://WOS:000075669400016 VL - 56 ID - 2892 ER - TY - JOUR AB - Just U, Oelkers R, Bender S, Parzer P, Ebinger F, Weisbrod M, Resch F. Emotional and behavioral problems in children and adolescents with primary headache. Cephalalgia. 2003;23:206-213. Psychiatric co-morbidity is an important risk factor for chronification of primary headache into adulthood. The aim of this study was to investigate the extent and clinical relevance of emotional and behavioral problems in children and adolescents with primary headache. Children and adolescents (n = 128) with primary headache (International Headache Society, codes 1.1, 1.2, 2.1) and 83 matched controls aged 6-18 years were examined by standardized dimensional psychometric tests (Child Behavior Checklist, Depression Inventory for Children and Adolescents, Anxiety Questionnaire for Pupils). Children and adolescents with primary headache suffer more often from internalizing problems (depression, anxiety, and somatization) than healthy controls. The detected emotional and behavioral problems are clinically relevant and require particular therapy in every third child suffering from headache. Two out of three children and adolescents with primary headache do not show clinically relevant psychopathology and may benefit from minimal therapeutic intervention. One of three examined headache patients needs additional psychiatric therapy. Smith MS, Martin-Herz SP, Womack WM, Marsigan JL. Comparative study of anxiety, depression, somatization, functional disability, and illness attribution in adolescents with chronic fatigue or migraine. Pediatrics. 2003;111(4 Pt 1):e376-e381. Objective: To compare adolescents with migraine, unexplained profound chronic fatigue of >6 months duration, and normal school controls on measures of anxiety, depression, somatization, functional disability, and illness attribution. Methods: Adolescents referred to Children's Hospital and Regional Medical Center for behavioral treatment of migraine (n = 179) or evaluation of chronic fatigue (n = 97) were compared with a group of healthy controls of similar age and sex from a middle school (n = 32). Subjects completed the Spielberger State-Trait Anxiety Inventory-Trait Form, the Children's Depression Inventory, the Childhood Somatization Inventory, and estimated the number of school days missed in the past 6 months because of illness. Migraine and fatigued subjects completed an illness attribution questionnaire. Results: Subjects in the 3 groups were 56% to 70% female and ranged from 11 to 18 years old with a mean age of 14.0 ± 2.0. Forty-six of the 97 chronically fatigued adolescents met 1994 Centers for Disease Control and Prevention (CDC) criteria for chronic fatigue syndrome (CDC-CFS), while 51 had idiopathic chronic fatigue syndrome (I-CFS) that did not meet full CDC criteria. Adolescents with migraine had significantly higher anxiety scores than those with I-CFS or controls and higher somatization scores than controls. Adolescents with CDC-CFS had significantly higher anxiety scores than those with I-CFS or controls, and higher depression and somatization scores than all other groups. There were significant differences between all groups for school days missed with CDC-CFS more than I-CFS more than migraine more than controls. Parents of adolescents with unexplained I-CFS had significantly lower attribution scores relating illness to possible psychological or stress factors than parents of adolescents with CDC-CFS or migraine. Conclusions: Adolescents referred to an academic center for evaluation of unexplained chronic fatigue had greater rates of school absenteeism than adolescents with migraine or healthy controls. Those meeting CDC-CFS criteria had higher anxiety scores than controls and higher depression and somatization scores than migraineurs or controls. Parents of adolescents with I-CFS were less likely to endorse psychological factors as possibly contributing to their symptoms than parents of adolescents with CDC-CFS or migraine. Comment: I included these two studies because of the comorbidity of migraine, depression, and anxiety. Note that migraine alone w s associated with less school absenteeism than in fatigue patients, while teens with fatigue had higher anxiety scores than migraine patients. However, the migraine patients had more 'internalizing problems (depression, anxiety, and somatization) than healthy controls,' with one-third meriting psychiatric intervention. Stewart J. Tepper Migraine studies in children often have a high-placebo response rate, which makes it difficult to demonstrate the therapeutic benefit or gain for a new therapy over and above placebo. The high prevalence of psychiatric comorbidity may explain the high-placebo response rate and confounding therapeutic benefits of specific therapies such as the triptans which have little or no known direct effects on depression, anxiety or somatization. This is in contrast to the use of SSRIs as prophylactic treatments which have may many nonspecific effects on the serotonerigc systems. David S. Millson Hershey AD. Chronic daily headaches in children. Expert Opin Pharmacother. 2003;4:485-491. Chronic daily headache (CDH) or highly frequent headaches are being recognized as an increasing problem. In adults it is estimated that up to 4% of the population has CDH, however, this number appears to be lower in children. The actual prevalence of CDH in children, however, has not been determined. The simplest definition of CDH is >15 headache days per month. In the international headache society (IHS) criteria, only chronic tension-type headaches and chronic cluster headaches are recognized as CDH. Criteria for CDH have been suggested for adults that mirror the IHS criteria. In children, the majority of CDH appear to be migraine-related. The next revision of the IHS criteria has been proposed to include chronic migraine as one of the CDH. Evaluation of CDH needs to include a complete history and physical examination to identify any possibility of the headache representing secondary headaches. Treatment and management involves a multitiered approach, which includes abortive therapy when the headache becomes more severe. With the precaution of avoiding overuse of analgesic medication, prophylactic therapy is used to help reduce the characteristics of the headache as well as the frequency and mild behavioral therapy. Comment: What is the prevalence of CDH in children? We do not have the data on this group, unlike the 4% found in the general population in both the studies by Scher AI, Stewart WF, Liberman J, Lipton RB. Prevalence of Frequent Headache in a Poulation Sample. Headache. 1998;38:497-506 and by Castillo J, Munoz P, Guitera V, Pascual J. Epidemiology of chronic daily headache in the general population. Headache. 1999;38:190-196. Stewart J. Tepper AN - 106028937. Language: English. Entry Date: 20070101. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical DB - cin20 DP - EBSCOhost IS - 6 N1 - Peer Reviewed; USA. NLM UID: 2985091R. PY - 2004 SN - 0017-8748 SP - 627-628 ST - Pediatric migraine T2 - Headache: The Journal of Head & Face Pain TI - Pediatric migraine UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106028937&site=ehost-live&scope=site VL - 44 ID - 769 ER - TY - JOUR AB - Recurrent abdominal pain of childhood affects up to 15% of school-age children, who face significant psychosocial consequences, including school absence. Because assessment of recurrent abdominal pain is frequently made at the school nurse level, a questionnaire was sent to 425 school nurses to evaluate perceptions about recurrent abdominal pain. Among the responses, 47.1% believed children were taking or seeking attention; 3.6% considered it a serious disease, 77.9% stated that affected children should see a physician, 51.5% believed they should relax, and 25.0% believed they needed medicine. Results indicated that school nurses were unclear on epidemiologic and etiologic features of recurrent abdominal pain and had negative views that may inadvertently contribute to the anxiety felt by affected children. Education of school nurses and communication from physicians may advance strategies designed to reduce the fiscal and social costs associated with this common childhood condition. AN - 105869197. Language: English. Entry Date: 20080321. Revision Date: 20200708. Publication Type: Journal Article DB - cin20 DO - 10.1177/0009922806296396 DP - EBSCOhost IS - 4 KW - Abdominal Pain -- Etiology Attitude to Health Interprofessional Relations Perception Physicians Schools, Nursing -- Education Abdominal Pain -- Psychosocial Factors Adult Child Female Male Malingering -- Psychosocial Factors Recurrence School Health Services Sex Factors Surveys Human N1 - research. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Peer Reviewed; USA. NLM UID: 0372606. PMID: NLM17475993. PY - 2007 SN - 0009-9228 SP - 340-344 ST - School nurse knowledge and perceptions of recurrent abdominal pain: opportunity for therapeutic alliance? T2 - Clinical Pediatrics TI - School nurse knowledge and perceptions of recurrent abdominal pain: opportunity for therapeutic alliance? UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105869197&site=ehost-live&scope=site VL - 46 ID - 709 ER - TY - JOUR AB - BACKGROUND: Health-related quality of life (HRQL) is frequently used as an outcome criterion to evaluate the quality and effect of different therapies. However, little is known about the HRQL of the general population, the prevalence of specific HRQL problems and about which factors have an impact on HRQL assessments. OBJECTIVE: To examine children's HRQL from their own and their parents' perspectives. The study sample consisted of children attending the third and fourth grades of elementary school in the capital of Austria, Europe. METHODS: One thousand four hundred twelve children and 1185 parents completed child- and parent-versions of the Pediatric Quality of Life Inventorytrade mark (PedsQLtrade mark). In addition to the PedsQL questions, children and parents were asked a number of questions with regard to sociodemographic information and specific problems that were hypothesized to be associated with the children's HRQL. RESULTS: Altogether, the children demonstrated a good HRQL and their PedsQL scores were similar to those of children from other developed countries. About 15% of children showed a notably low HRQL, and two-thirds of these children were from financially less privileged families. Multivariate regression analyses identified the following factors associated with the children's HRQL: the family's perceived financial situation, parents' quality of life, children's school performance, medical and/or psychologic problems (eg, dyslexia, recurrent stomachache or headaches), chronic disease, a recent life-event (eg, divorce/separation of parents), and parents' satisfaction with school. CONCLUSIONS: Assessing children's HRQL may be helpful to take preventive action and to identify those who are in urgent need of special services. AN - 105737236. Language: English. Entry Date: 20080606. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical DB - cin20 DP - EBSCOhost IS - 4 KW - Child Behavior Parents -- Psychosocial Factors Quality of Life Austria Child Female Health Status Interpersonal Relations Male Mental Health Socioeconomic Factors N1 - Peer Reviewed; USA. NLM UID: 0230027. PMID: NLM18362824. PY - 2008 SN - 0025-7079 SP - 432-439 ST - Health-related quality of life in Austrian elementary school children T2 - Medical Care TI - Health-related quality of life in Austrian elementary school children UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105737236&site=ehost-live&scope=site VL - 46 ID - 687 ER - TY - JOUR AN - 105320471. Language: English. Entry Date: 20091016. Revision Date: 20150711. Publication Type: Journal Article DB - cin20 DP - EBSCOhost IS - 1 KW - Academic Achievement Adult Child Chronic Pain -- Prevention and Control Clinical Assessment Tools Depression Family Role Female Grief Male Nicotine -- Therapeutic Use Pressure Ulcer Spinal Cord Injuries -- Psychosocial Factors Spinal Cord Injuries -- Rehabilitation Veterans -- Psychosocial Factors N1 - abstract. Journal Subset: Allied Health; Blind Peer Reviewed; Editorial Board Reviewed; Peer Reviewed; USA. NLM UID: 9215067. PY - 2008 SN - 1543-1088 SP - 47-54 ST - Selected abstracts from the 2007 AASCIPSW conference T2 - SCI Psychosocial Process TI - Selected abstracts from the 2007 AASCIPSW conference UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105320471&site=ehost-live&scope=site VL - 21 ID - 689 ER - TY - JOUR AN - 107988611. Language: English. Entry Date: 20130315. Revision Date: 20150712. Publication Type: Journal Article DB - cin20 DP - EBSCOhost IS - 7 KW - Absenteeism Parent-Child Relations Parents Sick Role Adolescence Adult Child Chronic Pain -- Rehabilitation Schools N1 - brief item. Journal Subset: Nursing; USA. Special Interest: Pain and Pain Management; Pediatric Care. PY - 2012 SN - 1048-3896 SP - 6-7 ST - Hurts Too Much to Attend School T2 - School Health Alert TI - Hurts Too Much to Attend School UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=107988611&site=ehost-live&scope=site VL - 27 ID - 561 ER - TY - JOUR AB - The article discusses some of the successes achieved by different trail campaigns for helping people caring with people with disabilities. It mentions that British medical research charity firm BackCare has released a "Carer's Guide" with a free DVD that features safe moving and handling techniques and started the "Global Schoolbag Campaign" to protect children's spines. It highlights that "Builder's Back Pain" was the theme of the 2012 Awareness Week for those suffering from chronic back pain. AN - 88002649. Language: English. Entry Date: 20130612. Revision Date: 20190620. Publication Type: Article DA - Spring2013 DB - cin20 DP - EBSCOhost KW - Back Pain Health Education Lobbying Back Injuries -- Prevention and Control Construction Industry Congresses and Conferences United Kingdom United States Back Pain -- Prevention and Control Backpacks -- In Infancy and Childhood School Health -- Legislation and Jurisprudence -- United States Child N1 - pictorial. Journal Subset: Consumer Health; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. Special Interest: Pain and Pain Management. PY - 2013 SN - 0144-3798 SP - 14-14 ST - Campaign trail update T2 - BackCare Journal TI - Campaign trail update UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=88002649&site=ehost-live&scope=site ID - 531 ER - TY - JOUR AB - The article reports on the U.S. Food and Drug Administration's (FDA) approval of the migraine preventing drug Topamax for teenagers. It mentions the potential of the medication in handling seizures and headaches which affect the social interaction, family life and school performance of adolescents. Furthermore, the agency's Division of Neurology Products deputy director Eric Bastings notes the benefits of dosage and safety information in treatment decisions. AN - 98806516. Language: English. Entry Date: 20141015. Revision Date: 20141016. Publication Type: Article DB - cin20 DP - EBSCOhost IS - 4 KW - Adolescence Migraine -- Drug Therapy Topiramate -- Administration and Dosage Drug Approval United States Food and Drug Administration N1 - pictorial. Journal Subset: Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Pain and Pain Management; Pediatric Care. NLM UID: 100956395. PY - 2014 SN - 1080-7543 SP - 19-19 ST - FDA approves Topamax for migraine prevention in adolescents T2 - School Nurse News TI - FDA approves Topamax for migraine prevention in adolescents UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=98806516&site=ehost-live&scope=site VL - 31 ID - 476 ER - TY - JOUR AB - The article focuses on a Norwegian study, published in "BMC Nursing," which revealed that school nurses interpret chronic pain in adolescents as a social, physical and psychological phenomenon. AN - 127519234. Language: English. Entry Date: 20180131. Revision Date: 20180131. Publication Type: Article DB - cin20 DP - EBSCOhost IS - 12 KW - Chronic Pain -- Etiology -- In Infancy and Childhood Pain -- Psychosocial Factors Nurse Attitudes -- Norway Child N1 - brief item; pictorial. Supplement Title: Dec2017/Jan2018. Journal Subset: Blind Peer Reviewed; Core Nursing; Europe; Nursing; Peer Reviewed; Public Health; UK & Ireland. NLM UID: 9809060. PY - 2017 SN - 1462-2815 SP - 11-11 ST - School nurses say pain has complex causes T2 - Community Practitioner TI - School nurses say pain has complex causes UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=127519234&site=ehost-live&scope=site VL - 90 ID - 333 ER - TY - JOUR AB - Background: Migraine is the most common type of episodic headache. Migraine can affect the pediatric patients' life through absence from school and restricting inside-home and social activities. Objective: This study was done with the objective of investigating the prophylactic effect of levetiracetam on pediatric migraine headaches. Materials and Methods: In this before-after clinical trial, 30 children aged 4–14 years with migraine headache were included and followed for 6 months. The required data were gathered through observation, examination, paraclinical studies, and interview. The data were entered into a checklist. Furthermore, the Pediatric Migraine Disability Assessment (PedMIDAS) questionnaire was used to assess disability. Levetiracetam tablet was administered for 6 months. The frequency and duration of migraine headaches as well as migraine-related symptoms and possible side effects were documented. The data were then analyzed by the SPSS software (ver. 20.0, IBM Company). Results: The frequency of headaches, their severity, and duration decreased significantly at the end of the study (P < 0.001). After 6 months of treatment, migraine attacks were recovered completely in six patients (20%). Only three patients (10%) showed side effects such as nagging and negotiating, poor sleep, and lack of appetite which neither resulted in cessation of the medication. Furthermore, the PedMIDAS score decreased significantly at the end of the study (P < 0.001). Conclusion: Levetiracetam had acceptable efficacy and tolerability to be used for prophylaxis of migraine headache in children and can be a good substitute in such patients. AN - 133737430. Language: English. Entry Date: 20190102. Revision Date: 20190619. Publication Type: Article DB - cin20 DO - 10.4103/ATMPH.ATMPH_499_17 DP - EBSCOhost IS - 6 KW - Anticonvulsants -- Therapeutic Use Migraine -- Drug Therapy -- In Infancy and Childhood Human Child, Preschool Child Adolescence Clinical Trials Interviews Checklists Anticonvulsants -- Administration and Dosage Disease Duration Migraine -- Symptoms Anticonvulsants -- Adverse Effects Severity of Illness Descriptive Statistics Recovery Negotiation Sleep Appetite Diaries Physical Examination Data Analysis Software Data Analysis, Statistical Paired T-Tests Effect Size Male Female Time Factors Fisher's Exact Test Headache -- Psychosocial Factors Nausea Photophobia Repeated Measures Analysis of Variance Questionnaires N1 - clinical trial; research; tables/charts. Journal Subset: Asia; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; Public Health. Instrumentation: Pediatric Migraine Disability Assessment (PedMIDAS) questionnaire. NLM UID: 101491477. PY - 2017 SN - 1755-6783 SP - 1547-1551 ST - Prophylactic efficacy of levetiracetam on migraine headaches in children aged 4–14-year-old T2 - Annals of Tropical Medicine & Public Health TI - Prophylactic efficacy of levetiracetam on migraine headaches in children aged 4–14-year-old UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=133737430&site=ehost-live&scope=site VL - 10 ID - 336 ER - TY - CASE A4 - Patra, Suravi A2 - Patnaik, Ashis AB - The article presents a case study of a 14‑year‑old younger son of a school teacher, has brought with chief complaints of not being able to focus in studies. Topics include moyamoya disease has a rare progressive cerebrovascular condition resulting in bilateral stenosis of internal carotid artery; and domains of cognitive functioning such as intelligence, memory, and executive functioning have affected. AD - Departments of Psychiatry, AIIMS, Bhubaneswar, Odisha, India Departments of Neurosurgery, AIIMS, Bhubaneswar, Odisha, India DB - cin20 DO - 10.4103/psychiatry.IndianJPsychiatry_403_18 DP - EBSCOhost J2 - Indian Journal of Psychiatry KW - Moyamoya Disease -- Diagnosis -- In Adolescence Attention Deficit Hyperactivity Disorder Adolescence Male Behavioral Symptoms Electroencephalography Magnetic Resonance Imaging Angiography, Digital Subtraction Moyamoya Disease -- Surgery Seizures -- Drug Therapy Phenytoin -- Therapeutic Use Carbamazepine -- Therapeutic Use Atomoxetine -- Therapeutic Use Headache -- Prevention and Control N1 - Accession Number: 138924803. Language: English. Entry Date: 20191007. Revision Date: 20200227. Publication Type: Case Study; case study; diagnostic images; letter. Journal Subset: Asia; Biomedical. NLM UID: 0013255. PB - Wolters Kluwer India Pvt Ltd PY - 2019 SP - 544-545 ST - Pediatric moyamoya disease presenting as attention deficit hyperactivity disorder: Time to pay attention TI - Pediatric moyamoya disease presenting as attention deficit hyperactivity disorder: Time to pay attention UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=138924803&site=ehost-live&scope=site VL - 61 ID - 220 ER - TY - JOUR AB - Objectives: Between 4% and 25% of school-aged children complain of recurrent abdominal pain (RAP) severe enough to interfere with their daily activities.Methods: We carried out a systematic review of randomised controlled trials (RCTs) in eleven databases and 2 trials registries from inception to June 2016. An update search was run in November 2017. All screening was performed by 2 independent reviewers. Included studies were appraised using the Cochrane risk of bias tool and the evidence assessed using GRADE. We included any dietary, pharmacological or psychosocial intervention for RAP, defined by Apley or an abdominal pain-related functional gastrointestinal disorder, as defined by the Rome III criteria, in children and adolescents.Results: We included 55 RCTs, involving 3572 children with RAP (21 dietary, 15 pharmacological, 19 psychosocial, and 1 multiarm). We found probiotic diets, cognitive-behavioural therapy (CBT) and hypnotherapy were reported to reduce pain in the short-term and there is some evidence of medium term effectiveness. There was insufficient evidence of effectiveness for all other dietary interventions and psychosocial therapies. There was no robust evidence of effectiveness for pharmacological interventions.Conclusions: Overall the evidence base for treatment decisions is poor. These data suggest that probiotics, CBT, and hypnotherapy could be considered as part of holistic management of children with RAP. The evidence regarding relative effectiveness of different strains of probiotics is currently insufficient to guide clinical practice. The lack of evidence of effectiveness for any drug suggests that there is little justification for their use outside of well-conducted clinical trials. There is an urgent need for high-quality RCTs to provide evidence to guide management of this common condition. AD - NIHR CLAHRC South West Peninsula (PenCLAHRC), University of Exeter Medical School, Exeter, Exeter, UK Bristol Royal Hospital for Children, Bristol, Exeter, UK University of Exeter Medical School, Exeter, UK NIHR CLAHRC South West Peninsula (PenCLAHRC), University of Exeter Medical School, Exeter AN - 130376543. Language: English. Entry Date: 20180914. Revision Date: 20191027. Publication Type: journal article AU - Abbott, Rebecca A. AU - Martin, Alice E. AU - Newlove-Delgado, Tamsin V. AU - Bethel, Alison AU - Whear, Rebecca S. AU - Coon, Jo Thompson AU - Logan, Stuart AU - Thompson Coon, Jo DB - cin20 DO - 10.1097/MPG.0000000000001922 DP - EBSCOhost IS - 1 KW - Abdominal Pain -- Therapy -- In Infancy and Childhood Chronic Pain -- Therapy Recurrence Treatment Outcomes Human Child Systematic Review Meta Analysis AMED Database CINAHL Database Embase ERIC Database Medline Psycinfo N1 - meta analysis; research; systematic review; tables/charts. Journal Subset: Allied Health; USA. Special Interest: Evidence-Based Practice. NLM UID: 8211545. PMID: NLM29470291. PY - 2018 SN - 0277-2116 SP - 23-33 ST - Recurrent Abdominal Pain in Children: Summary Evidence From 3 Systematic Reviews of Treatment Effectiveness T2 - Journal of Pediatric Gastroenterology & Nutrition TI - Recurrent Abdominal Pain in Children: Summary Evidence From 3 Systematic Reviews of Treatment Effectiveness UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=130376543&site=ehost-live&scope=site VL - 67 ID - 299 ER - TY - JOUR AB - The prevalence and clinical features of migraine headache and abdominal migraine were studied in the well defined population of Aberdeen schoolchildren. Ten per cent of all children (2165) aged 5-15 years were given a questionnaire inquiring, among other symptoms, about the history of headache and abdominal pain over the past year. A total of 1754 children (81%) responded. Children with at least two episodes of severe headache and/or sever abdominal pain, attributed by the parents either to unknown causes or to migraine, were invited to attend for clinical interview and examination. After interview, 159 children fulfilled the International Headache Society's criteria for the diagnosis of migraine and 58 children had abdominal migraine giving estimated prevalence rates of 10.6% and 4.1% respectively. Children with abdominal migraine had demographic and social characteristics similar to those of children with migraine. They also had similar patterns of associated recurrent painful conditions, trigger and relieving factors, and associated symptoms during attacks. The similarities between the two conditions are so close as to suggest that they have a common pathogenesis. AD - Department of Medical Paediatrics, Royal Aberdeen Children's Hospital, Foresterhill AN - 66463585. Language: English. Entry Date: 19970901. Revision Date: 20190505. Publication Type: journal article AU - Abu-Arafeh, Ishaq AU - Russell, George AU - Abu-Arafeh, I. AU - Russell, G. DB - cin20 DP - EBSCOhost IS - 5 KW - Abdominal Pain -- Epidemiology Migraine -- Epidemiology Male Recurrence Adolescence Child, Preschool Migraine -- Therapy Abdominal Pain -- Therapy Abdominal Pain -- Etiology Demography Human Scotland Child Female Prevalence Migraine -- Etiology Validation Studies Comparative Studies Evaluation Research Multicenter Studies Scales Social Readjustment Rating Scale N1 - research. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Instrumentation: Clinical Decision Making in Nursing Scale (CDMNS) (Jenkins); Social Readjustment Rating Scale (SRRS) (Holmes and Rahe). NLM UID: 0372434. PMID: NLM7618907. PY - 1995 SN - 0003-9888 SP - 413-417 ST - Prevalence and clinical features of abdominal migraine compared with those of migraine headache T2 - Archives of Disease in Childhood TI - Prevalence and clinical features of abdominal migraine compared with those of migraine headache UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=66463585&site=ehost-live&scope=site VL - 72 ID - 850 ER - TY - JOUR AB - Background: Children with cerebral palsy (CP) face particular challenges, e.g. daily pain that threaten their participation in school activities. This study focuses on how teachers, personal assistants, and clinicians in two countries with different cultural prerequisites, Sweden and South Africa, manage the pain of children in school settings. Method: Participants' statements collected in focus groups were analysed using a directed qualitative content analysis framed by a Frequency of attendance-Intensity of involvement model, which was modified into a Knowing-Doing model. Results: Findings indicated that pain management focused more on children's attendance in the classroom than on their involvement, and a difference between countries in terms of action-versus-reaction approaches. Swedish participants reported action strategies to prevent pain whereas South African participants primarily discussed interventions when observing a child in pain. Conclusion: Differences might be due to school- and healthcare systems. To provide effective support when children with CP are in pain in school settings, an action-and-reaction approach would be optimal and the use of alternative and augmentative communication strategies would help to communicate children's pain. As prevention of pain is desired, structured surveillance and treatment programs are recommended along with trustful collaboration with parents and access to "hands-on" pain management when needed. AD - CHILD, Jönköping University, Jönköping, Sweden School of Education and Communication, Jönköping University, Jönköping, Sweden Swedish Institute of Disability Research, Jönköping University, Jönköping, Sweden Centre for Augmentative and Alternative Communication, University of Pretoria, Pretoria, South Africa Institute of Health and Care Sciences, University of Gothenburg, Gothenburg, Sweden AN - 130496724. Language: English. Entry Date: 20180709. Revision Date: 20200224. Publication Type: Article AU - Adolfsson, Margareta AU - Johnson, Ensa AU - Nilsson, Stefan DB - cin20 DO - 10.1080/09638288.2017.1327987 DP - EBSCOhost IS - 18 KW - Pain Management -- In Infancy and Childhood -- Sweden Cerebral Palsy -- Sweden Cerebral Palsy -- South Africa Pain Management -- In Infancy and Childhood -- South Africa Human Convenience Sample Purposive Sample Sweden South Africa Child Schools -- Sweden Qualitative Studies Focus Groups Content Analysis Models, Theoretical Schools -- South Africa Parents N1 - research; tables/charts. Journal Subset: Allied Health; Europe; Peer Reviewed; UK & Ireland. NLM UID: 9207179. PY - 2018 SN - 0963-8288 SP - 2152-2162 ST - Pain management for children with cerebral palsy in school settings in two cultures: action and reaction approaches T2 - Disability & Rehabilitation TI - Pain management for children with cerebral palsy in school settings in two cultures: action and reaction approaches UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=130496724&site=ehost-live&scope=site VL - 40 ID - 289 ER - TY - JOUR AB - Migraines occur in young children, but may be challenging to diagnose. Migraines can have a great impact on pediatric patients' quality of life with school absence and limitations on extracurricular activities. Treatment of pediatric migraines or possible migraines is difficult secondary to the lack of evidence for effective therapies in pediatric patients. Treatment includes traditional therapy with dopamine receptor antagonists (DRAs), nonsteroidal anti-inflammatory drugs (NSAIDs), triptans, and combination therapies. Newer therapies include magnesium, valproic acid (VPA), and peripheral nerve blocks. The authors review the clinical presentation of migraines in children, guidelines for diagnosis, and therapeutic options. AN - 135516333. Language: English. Entry Date: 20190327. Revision Date: 20190711. Publication Type: Article AU - Ahc, Media DB - cin20 DP - EBSCOhost IS - 4 KW - Pediatric Care Migraine -- Therapy Headache -- Therapy Child Migraine -- Epidemiology Quality of Life Migraine -- Physiopathology Migraine -- Diagnosis Neuroradiography Migraine -- Symptoms Migraine -- Classification Ibuprofen -- Administration and Dosage Acetaminophen -- Administration and Dosage Dopamine Antagonists -- Administration and Dosage Antiinflammatory Agents, Non-Steroidal -- Administration and Dosage Magnesium -- Administration and Dosage Dihydroergotamine -- Administration and Dosage Analgesics, Opioid -- Administration and Dosage Nerve Block Valproic Acid -- Administration and Dosage Adrenal Cortex Hormones -- Administration and Dosage Propofol -- Administration and Dosage N1 - algorithm; tables/charts. Journal Subset: Biomedical; USA. NLM UID: 9889703. PY - 2019 SN - 1082-3344 SP - 0-0 ST - Acute Treatment of Pediatric Migraine T2 - Pediatric Emergency Medicine Reports TI - Acute Treatment of Pediatric Migraine UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=135516333&site=ehost-live&scope=site VL - 24 ID - 256 ER - TY - JOUR AB - Background: Back pain is an important public health problem and the leading cause of adult disability worldwide and is rising among schoolchildren populations. Despite numerous studies reporting on back care interventions in pediatric population; there is currently no existing theory-based instrument to assess impact and outcome of these programs. This paper reports on development and psychometric testing of a theory based back-care behavior instrument for use among elementary schoolchildren.Methods: This was a three-phases study that included the following steps: a) a literature research to review existing instruments that assess healthy spine-related behavior in elementary schoolchildren; b) development of a new instrument namely the Back-care Behavior Assessment Questionnaire (BABAQ) based on the Social Cognitive Theory and existing instruments, and c) conducting a cross sectional study to test psychometric properties of the BABAQ by estimating the content validity ratio (CVR), the content validity index (CVI), performing confirmatory factor analysis (CFA), reliability analysis, and convergent validity as estimated by the Average Variance Extracted (AVE).Results: First, a questionnaire (the BABAQ) was developed. It contained of 49 items tapping into 5 pre-defined constructs (skills, knowledge, self-efficacy, expectation beliefs, and behavior). Then, 610 fifth-grade female schoolchildren were entered into a cross sectional study and they completed the BABAQ. The CVR and the CVI of the questionnaire was found to be ≥0.54 and > 0.7, respectively. The CFA confirmed the five constructs and showed good fit for the data. The intraclass correlation (ICC) and the Cronbach's alpha coefficients for the BABAQ were 0.84 (P < 0.001) and 0.93, respectively. The convergent validity as measured by the AVE also showed satisfactory results.Conclusion: The findings suggest that the Back-care Behavior Assessment Questionnaire (BABAQ) is a valid instrument for measuring healthy spine-related behaviors among schoolchildren. AD - Department of Health Education, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran Health Metrics Research Center, Iranian Institutes for Health Sciences Research, ACECR, Tehran, Iran Faculty of Humanity Sciences, University of Science &Culture, ACECR, Tehran, Iran AN - 145300480. Language: English. Entry Date: In Process. Revision Date: 20201203. Publication Type: journal article. Journal Subset: Biomedical AU - Akbari-Chehrehbargh, Zahra AU - Sadat Tavafian, Sedigheh AU - Montazeri, Ali DB - cin20 DO - 10.1186/s12889-020-09318-9 DP - EBSCOhost IS - 1 KW - Psychometrics -- Methods Back Pain -- Psychosocial Factors Students -- Psychosocial Factors Back Pain -- Therapy Students -- Statistics and Numerical Data Reproducibility of Results Female Child Iran Cross Sectional Studies Factor Analysis Impact of Events Scale Social Readjustment Rating Scale N1 - Europe; Public Health; UK & Ireland. Instrumentation: Impact of Events Scale (IES); Social Readjustment Rating Scale (SRRS) (Holmes and Rahe). NLM UID: 100968562. PMID: NLM32842995. PY - 2020 SN - 1471-2458 SP - N.PAG-N.PAG ST - The Back-care Behavior Assessment Questionnaire (BABAQ) for schoolchildren: development and psychometric evaluation T2 - BMC Public Health TI - The Back-care Behavior Assessment Questionnaire (BABAQ) for schoolchildren: development and psychometric evaluation UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=145300480&site=ehost-live&scope=site VL - 20 ID - 175 ER - TY - JOUR AB - To define the learning needs of patients with gynecological oncology. The study was performed as a descriptive study. A total of 92 patients were participated. Data were collected using Patient Learning Needs Scale (PLNS). The Pearson correlation test, independent sample t test, and analysis of one-way of variance (ANOVA) followed by Tukey's-B post hoc tests were used for statistical analyses by the SPSS 15.0 software package. The mean age of women's was 50.37 ± 12.20 years. The women's diagnoses were cervical (45.7 %), ovarian (27.2 %), and endometrial (19.6 %) cancers. The most frequently stated learning needs topics were coping with pain (47.8 %), daily living activities (46.2 %), and psychological support (44.6 %). The mean PLNS score of women was 212.56 ± 35.83. The mean subscales scores of PLNS were 34.06 ± 7.29 for medicines, 38.34 ± 6.74 for daily living activities, and 24.68 ± 5.41 for community subscales. Women who graduated from elementary school needed more education than the women with higher education (p < 0.001). Learning needs level of the women are high and related to increase quality of life, medicine usage, complications of treatment, skin problems, pain management, and supportive care. As a healthcare professional, we should plan and develop educational programs in order to adequately inform patients about their learning needs. AD - Department of Nursing, Faculty of Health Sciences, Baskent University, Ankara, Turkey Department of Obstetrics and Gynecology Nursing, Gulhane School of Nursing, University of Health Sciences, Ankara, Turkey Nursing Services Directorate of Adult Hospital, Hacettepe University, Ankara, Turkey Obstetrics and Gynecology Service, Gazi University Hospital, Ankara, Turkey Department of Obstetrics and Gynecology, Faculty of Medicine, Baskent University, Ankara, Turkey AN - 129594356. Language: English. Entry Date: 20191002. Revision Date: 20210110. Publication Type: journal article AU - Akkuzu, Gulcihan AU - Kurt, Gonul AU - Guvenc, Gulten AU - Kok, Gulsah AU - Simsek, Sevgi AU - Dogrusoy, Safiye AU - Ayhan, Ali DB - cin20 DO - 10.1007/s13187-016-1118-y DP - EBSCOhost IS - 3 KW - Patient Education -- Administration Genital Neoplasms, Female -- Psychosocial Factors Aged Socioeconomic Factors Adaptation, Psychological Adult Female Activities of Daily Living Quality of Life Pain -- Psychosocial Factors Pain -- Therapy Middle Age Learning N1 - research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Health Promotion/Education; Peer Reviewed; USA. NLM UID: 8610343. PMID: NLM27743314. PY - 2018 SN - 0885-8195 SP - 544-550 ST - Learning Needs of Gynecologic Cancer Survivors T2 - Journal of Cancer Education TI - Learning Needs of Gynecologic Cancer Survivors UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=129594356&site=ehost-live&scope=site VL - 33 ID - 304 ER - TY - JOUR AB - Background: Migraine prevalence and disability imprints on Kuwaiti population are underreported. We aimed to measure the prevalence of migraine and to assess its burden in Kuwait. Methods: A cross-sectional community-based study was conducted which included biologically unrelated Kuwaiti adult population aged 18-65 years. They were randomly recruited from all six governments of Kuwait using stratified multistage cluster sampling. Trained interviewers visited the samples in door-to-door approach. The Headache-Attributed Restriction, Disability, and Social Handicap and Impaired Participation (HARDSHIP) questionnaire was used to collect the data. Demographic enquires were followed by diagnostic and disability questions. Results: A total of 15,523 subjects were identified; of whom 3588 (23%) were diagnosed as episodic migraine and 845 (5.4%) as chronic headache. Prevalence of episodic migraine was 31.71% in female versus 14.88% in males ( P < 0.01) with a mean age of 34.56 ± 10.17 years. Most of migraine cohort (64.4%) sought medical advice with respect to their migraine headaches and the majority (62.4%) were seen by general practitioners (GPs) while 17.2% were assessed by neurologists and 3.7% was seen by other specialties. Tension type headache and sinus-related headaches were diagnosed in 8.9% and 2.1% of migraine subjects respectively. The majority (94.6%) of migraine subjects used symptomatic drugs for headache attacks, whereas 39.9% were taking preventive medication. In the preceding 3 months to the survey, subjects with episodic migraine had lost a mean of 1.97 days from their paid work or school attendance compared to 6.62 days in chronic headache sufferers ( P < 0.001). Additionally, subjects with episodic migraine lost a mean of 1.40 days from household work compared to 5.35 days in subjects with chronic headache ( P < 0.001). Participants with episodic migraine and chronic headache missed a mean of 2.81 and 3.85 days on social occasions, in the preceding 3 months ( P < 0.001). Conclusions: Migraine in Kuwait is highly prevalent and it has a significant impact on activity of daily living, schooling/ employment and social occasions of patients. Accurate diagnosis, effective abortive and preventive treatments of migraine are paramount to improve quality of life and as well as cost saving. AD - Division of Neurology, Department of Medicine , Amiri Hospital , Sharq Kuwait AN - 125694827. Language: English. Entry Date: 20171019. Revision Date: 20171019. Publication Type: Article AU - Al-Hashel, Jasem AU - Ahmed, Samar AU - Alroughani, Raed DB - cin20 DO - 10.1186/s10194-017-0814-2 DP - EBSCOhost IS - 1 KW - Migraine -- Complications Surveys Population Human Kuwait Geographic Locations Migraine -- Diagnosis Cross Sectional Studies Adult Adolescence Middle Age Research Subject Recruitment Headache -- Complications Prevalence Physicians, Family Migraine -- Therapy Migraine -- Prevention and Control Migraine -- Epidemiology Data Analysis Software Male Female N1 - research; tables/charts. Journal Subset: Biomedical; Continental Europe; Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. NLM UID: 100940562. PY - 2017 SN - 1129-2369 SP - 1-6 ST - Burden of migraine in a Kuwaiti population: a door-to-door survey T2 - Journal of Headache & Pain TI - Burden of migraine in a Kuwaiti population: a door-to-door survey UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=125694827&site=ehost-live&scope=site VL - 18 ID - 338 ER - TY - JOUR AB - Background: Primary headache disorders have being increasingly reported in younger populations. They can have significant effects on their quality of life and academic achievement and may cause significant distress to their families. Aims and objectives: To assess the burden of primary headache disorder and its impact on the quality of life on school student in Kuwait. Methods: A cross-sectional study was conducted among Kuwaiti primary and middle school students of both genders in randomly selected schools located in two governorates in 2018/2019 academic year. Headache-Attributed Restriction, Disability, Social Handicap and Impaired Participation (HARDSHIP) questionnaire for children and adolescents was used to assess the impact of primary headaches on the quality of life. Results: One thousand and ninety-one questionnaires were completed by primary and middle school students of both genders; of whom 466 students (girls 321 (68.88%) were diagnosed with primary headache disorders with mean age 11.98 ± 2.03 years. In the month prior to the survey, the effect of the headache was variable. The students lost a mean of 1.99 ± 2.015 days of school while they could not perform their usual activities for a mean of 2.84 ± 4.28 days. Their parents lost a mean of 2 ± 2.03 days of work because of headaches of their children and parents prohibited 5.7% of the students to engage in any activity due to their headaches. Difficulties in concentrations were reported as never sometimes (39.1%), often (24.8%), and always (26%). Majority of the students (51.5%) experienced a feeling of sadness ranging from sometimes to always. Most of the students (67.3%) struggled to cope with the headache and 22.4% were never able to cope. Additionally, 19.4% of students reported they did not want others noticing their headache. Conclusion: Primary headache disorder can have a significant impact on the quality of life in children. It can affect their engagement in activities and academic achievement. Implementing strategies to properly manage schoolchildren with primary headaches can have profound effects on their quality of life. AD - Neurology Department, Ibn Sina Hospital, P.O. Box 25427, Safat, 13115, Kuwait City, Kuwait Department of Medicine, Faculty of Medicine, Health Sciences Centre, Kuwait University, P.O. Box 24923, Safat, 13110, Kuwait City, Kuwait Division of Neurology, Department of Medicine, Amiri Hospital, Arabian Gulf Street, 11013, Sharq, Kuwait Internal Medicine Department, Ministry of Health, Kuwait City, Kuwait Obstetrics and Gynecology Department, Ministry of Health, Kuwait City, Kuwait Neuropsychiatry department, Faculty of Medicine, Al-Minia University, P.O. Box 61519, 61111, Minia City, Minia, Egypt AN - 144220109. Language: English. Entry Date: 20200627. Revision Date: 20200629. Publication Type: Article AU - Al-Hashel, Jasem Y. AU - Alroughani, R. AU - Shauibi, S. AU - AlAshqar, A. AU - AlHamdan, F. AU - AlThufairi, H. AU - Owayed, S. AU - Ahmed, Samar F. DB - cin20 DO - 10.1186/s10194-020-01124-3 DP - EBSCOhost IS - 1 KW - Headache, Primary -- Diagnosis -- Kuwait Headache, Primary -- Psychosocial Factors -- Kuwait Quality of Life -- Evaluation -- Kuwait Students, Elementary -- Psychosocial Factors -- Kuwait Students, Middle School -- Psychosocial Factors -- Kuwait Kuwait Human Cross Sectional Studies Questionnaires Male Female Child Adolescence Surveys Sadness Coping Academic Achievement Random Sample N1 - research; tables/charts. Journal Subset: Biomedical; Continental Europe; Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. Instrumentation: Headache-Attributed Restriction, Disability, Social Handicap and Impaired Participation (HARDSHIP). NLM UID: 100940562. PY - 2020 SN - 1129-2369 SP - 1-6 ST - Impact of primary headache disorder on quality of life among school students in Kuwait T2 - Journal of Headache & Pain TI - Impact of primary headache disorder on quality of life among school students in Kuwait UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=144220109&site=ehost-live&scope=site VL - 21 ID - 183 ER - TY - JOUR AB - Background: Temporomandibular disorders (TMD) in children and adolescents is prevalent with pain as a common component, and has a comorbidity with psychosocial problems such as stress, depression, anxiety as well as somatic complaints. Therefore, the aim of the study was to investigate if psychosocial problems in children and adolescents are associated with TMD with pain (TMD-pain) and TMD without pain (TMD-painfree) when compared to children and adolescents without TMD. Methods: This cross-sectional study consisted of 456 randomly selected children and adolescents, enrolled from 10 boy's- and 10 girl's- schools in Jeddah, between 10 and 18 years of age. On the examination day, prior to the clinical examination according to Research Diagnostic Criteria for TMD Axis I and II, the participants first answered two validated questions about TMD pain, and after that the Arabic version of the Youth Self Report scale. According to their clinical examination and diagnosis the participants were divided into three groups; non-TMD group, TMD-pain group, and TMD-painfree group. Results: The TMD-pain group presents a higher frequency of the internalizing problems anxiety, depression and somatic complaints than non-TMD group ( p < 0.05). Regarding externalizing problems the only significant association found was for aggressive behavior in the TMD-pain group ( p < 0.05). The TMD-pain group also shows a higher frequency of social problems than the non-TMD group. However, no such difference was found when compared to the TMD-painfree group. There was also a significant association with a higher frequency of thought problems in the TMD-pain group ( p < 0.05). The children's and adolescents' physical activities were within border line clinical range for all three groups, whereas the social competence was within the normal range. There were no significant associations between any of the groups in this respect. Conclusions: TMD-pain in children and adolescents does not seem to affect the social activities. However, TMD-pain seem to have a strong association to emotional, behavior and somatic functioning, with higher frequencies of anxiety, depression, somatic problems, aggressive behavior and thought problems, than children and adolescents without TMD-pain. With respect to the biopsychosocial model the present study indicates that there are significant associations to psychosocial, somatic and behavioral comorbidities and TMD-pain in children and adolescents in the Middle East region. AD - Cariology, Department of Dental Medicine, Karolinska Institutet, SE-141 04 Huddinge Sweden Orofacial Pain and Jaw Function, Department of Dental Medicine, Karolinska Institutet, SE-141 04 Huddinge Sweden Dental Speciality Center, Ministry of Health, Jeddah Saudi Arabia Pediatric Dentistry and Orthodontics Department, College of Dentistry, King Saud University, Riyadh Saudi Arabia AN - 114246016. Language: English. Entry Date: 20171011. Revision Date: 20190308. Publication Type: Article AU - Al-Khotani, Amal AU - Naimi-Akbar, Aron AU - Gjelset, Mattias AU - Albadawi, Emad AU - Bello, Lanre AU - Hedenberg-Magnusson, Britt AU - Christidis, Nikolaos DB - cin20 DO - 10.1186/s10194-016-0622-0 DP - EBSCOhost IS - 1 KW - Temporomandibular Joint Diseases -- Psychosocial Factors -- In Infancy and Childhood Temporomandibular Joint Diseases -- Psychosocial Factors -- In Adolescence Pain Human Child Adolescence Male Female Cross Sectional Studies Saudi Arabia Temporomandibular Joint Diseases -- Complications Pain -- Etiology Pain -- Psychosocial Factors Mental Disorders Scales Clinical Assessment Tools P-Value N1 - research; tables/charts. Journal Subset: Biomedical; Continental Europe; Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. Special Interest: Pediatric Care. Instrumentation: Youth Self-Report (YSR) [Arabic]. NLM UID: 100940562. PY - 2016 SN - 1129-2369 SP - 1-10 ST - The associations between psychosocial aspects and TMD-pain related aspects in children and adolescents T2 - Journal of Headache & Pain TI - The associations between psychosocial aspects and TMD-pain related aspects in children and adolescents UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=114246016&site=ehost-live&scope=site VL - 17 ID - 411 ER - TY - JOUR AB - Background: Although dysmenorrhea is not a life-threatening condition, it can cause a substantial burden on individuals and communities. There is no data on the prevalence of dysmenorrhea in Kuwait. This study aimed to estimate the prevalence of dysmenorrhea among female public high-school students in Kuwait and investigate factors associated with dysmenorrhea.Methods: A cross-sectional study using multistage cluster sampling with probability proportional to size method was conducted on 763 twelfth grade female public high-school students (aged 16-21 years). We used face-to-face interview with a structured questionnaire to collect data on dysmenorrhea and presumed risk factors. Weight and height of the students were measured using appropriate weight and height scales in a standardized manner. The association between dysmenorrhea and potential risk factors was assessed using multiple logistic regression.Results: The one-year prevalence of dysmenorrhea was found to be 85.6% (95%CI: 83.1-88.1%). Of the participants with dysmenorrhea, 26% visited a public or a private clinic for their pain and 4.1% were hospitalized for their menstrual pain. Furthermore, 58.2% of students with dysmenorrhea missed at least one school day and 13.9% missed at least one exam. Age of menarche (p-value = 0.005), regularity and flow of the menstrual period (p-value = 0.025, p-value = 0.009; respectively), and drinking coffee (p-value = 0.004) were significantly associated with dysmenorrhea in multivariable analysis.Conclusion: Dysmenorrhea seems to be highly prevalent among female high-school students in Kuwait, resembling that of high-income countries. Because of the scale of the problem, utilizing school nurses to reassure and manage students with primary dysmenorrhea and referring suspected cases of secondary dysmenorrhea is recommended. AD - Department of Community Medicine and Behavioural Sciences, Faculty of Medicine, Kuwait University, Box: 24923, 13110, Safat, Kuwait AN - 135400398. Language: English. Entry Date: In Process. Revision Date: 20200312. Publication Type: journal article. Journal Subset: Biomedical AU - Al-Matouq, Sharefah AU - Al-Mutairi, Hessah AU - Al-Mutairi, Ohood AU - Abdulaziz, Fatima AU - Al-Basri, Dana AU - Al-Enzi, Mona AU - Al-Taiar, Abdullah DB - cin20 DO - 10.1186/s12887-019-1442-6 DP - EBSCOhost IS - 1 KW - Dysmenorrhea -- Epidemiology Dysmenorrhea -- Etiology Students Female Interviews Multivariate Analysis Menstrual Cycle Adolescence Coffee -- Adverse Effects Risk Factors Cross Sectional Studies Prevalence Young Adult Kuwait Menarche Socioeconomic Factors N1 - Europe; Peer Reviewed; UK & Ireland. Instrumentation: Longitudinal Interval Follow-Up Evaluation (LIFE). NLM UID: 100967804. PMID: NLM30885151. PY - 2019 SN - 1471-2431 SP - N.PAG-N.PAG ST - Dysmenorrhea among high-school students and its associated factors in Kuwait T2 - BMC Pediatrics TI - Dysmenorrhea among high-school students and its associated factors in Kuwait UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=135400398&site=ehost-live&scope=site VL - 19 ID - 258 ER - TY - JOUR AB - Headache is considered one of the most common complaints affecting all ages: children, adolescents, and adults. A school-based, cross-sectional study was conducted to assess primary headache among high school students aged 16–18 in Grades 11–12, over a period of 3 weeks (May 2017). A questionnaire was designed, in accordance with the International Headache Society's criteria. The Pearson's χ2 test was computed to show the differences between the variables. Nearly two thirds of the students reported having headache (19.0% tension-type headache, 8.8% migraine, and 39.0% unknown type). Nearly a quarter sought help for headache, and the most frequently used analgesic was acetaminophen (82.2%) followed by aspirin (5.1%). The current study revealed that the prevalence of headache and migraine was initially high and increased with age. Moreover, headache is one of the major public health problems among high school students. An education program conducted by school nurses and other health-care providers regarding headache and migraine is needed. AD - Community and Mental Health Department, Princess Salma Faculty of Nursing, Al al-Bayt University, Mafraq, Jordan Adult Healthcare Nursing Department, Faculty of Nursing, Al al-Bayt University, Mafraq, Jordan Faculty of Nursing, Al al-Bayt University, Mafraq, Jordan Adult Health Nursing, Faculty of Nursing, Al al-Bayt University, Mafraq, Jordan Mental Health Nursing, Faculty of Nursing, Al al-Bayt University, Mafraq, Jordan Adult Health Nursing, Faculty of Nursing, Philadelphia University, Amman, Jordan Faculty of Nursing, Philadelphia University, Amman, Jordan Princess Salma Faculty of Nursing, Al al-Bayt University, Mafraq, Jordan AN - 135388017. Language: English. Entry Date: 20190320. Revision Date: 20190325. Publication Type: Article AU - Albashtawy, Mohammed AU - Al Qadire, Mohammad AU - Aloush, Sami AU - Tawalbeh, Loai AU - AlAzzam, Manar AU - Suliman, Mohammad AU - Batiha, Abdul-Monim AU - Alhalaiqa, Fadwa AU - Alshakh, Hind AU - Abd Al-Rahman, Areej DB - cin20 DO - 10.1177/1059840517734613 DP - EBSCOhost IS - 2 KW - Headache -- Epidemiology -- Jordan Students, High School School Health Nursing Human Female Male Adolescence Jordan Cross Sectional Studies Questionnaires Pearson's Correlation Coefficient Chi Square Test Prevalence Headache -- Drug Therapy Public Health Headache -- Education School Health Pilot Studies Content Validity Descriptive Statistics Data Analysis Software N1 - research; tables/charts. Journal Subset: Nursing; Peer Reviewed; USA. NLM UID: 9206498. PY - 2019 SN - 1059-8405 SP - 88-95 ST - Assessment of Headache Among High School Students in Jordan T2 - Journal of School Nursing TI - Assessment of Headache Among High School Students in Jordan UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=135388017&site=ehost-live&scope=site VL - 35 ID - 255 ER - TY - JOUR AB - OBJECTIVES: To investigate the prospective value of the transitional and dynamic patterns of pain disability over time on sick leave in chronic recurrent back/neck pain cases. METHODS: The material used was based on a longitudinal study with three repeated measurements. The graded Chronic Pain Scale was used to assess levels of pain disability. The relationship between the transitional patterns of the pain disability score (ten defined states of decrease, increase or no change, between two time points) and sick leave was analyzed for 909 chronic/recurrent cases in three different models using logistic regression. RESULTS: Those with high level of pain disability have a more transitional pattern and their pain level changed during the time period studied. When adjusting for age, gender, education and previous sick leave, the final model indicated that the current level of pain disability was a risk factor in taking sick leave. The likelihood of sick leave was highest in the transition of pain into the highest levels of disability, independent of past disability level of pain. Earlier sick leave remained as an important predictor of sick leave. CONCLUSIONS: From a clinical and prognostic perspective the probability of sick leave will be different and can be predicted based on previous sick leave but not from former history of pain disability level or its transitional pattern. AD - Division of Intervention and Implementation Research, Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden AN - 104233530. Language: English. Entry Date: 20131009. Revision Date: 20200708. Publication Type: Journal Article AU - Alipour, Akbar AU - Bodin, Lennart AU - Bergstrom, Gunnar AU - Jensen, Irene DB - cin20 DO - 10.3233/BMR-130400 DP - EBSCOhost IS - 4 KW - Chronic Pain -- Physiopathology Back Pain -- Physiopathology Neck Pain -- Physiopathology Sick Leave Absenteeism Human Prospective Studies Scales Logistic Regression Sweden Occupational Health Questionnaires Male Female Descriptive Statistics Adult Odds Ratio Confidence Intervals Data Analysis Software Adolescence Middle Age Funding Source N1 - research; tables/charts. Journal Subset: Allied Health; Biomedical; Continental Europe; Europe; Peer Reviewed. Special Interest: Pain and Pain Management. Instrumentation: Graded Chronic Pain Scale (GCPS). Grant Information: This study was made possible by a grant from AFA insurance company.. NLM UID: 9201340. PMID: NLM23948828. PY - 2013 SN - 1053-8127 SP - 411-419 ST - The transitional pattern of pain and disability, from perceived pain to sick leave. Experience from a longitudinal study T2 - Journal of Back & Musculoskeletal Rehabilitation TI - The transitional pattern of pain and disability, from perceived pain to sick leave. Experience from a longitudinal study UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104233530&site=ehost-live&scope=site VL - 26 ID - 514 ER - TY - JOUR AB - Background: People living with cystic fibrosis experience pain that is associated with decreased quality of life, poorer health outcomes, and increased mortality. Though pain is highly prevalent as a symptom, it is currently unknown how persons with CF describe their pain experiences or the ways those experiences impact their lives. Aims: To explore and describe ways adolescents and adults with CF experience pain. Design/Setting/Subjects/Methods: An exploratory descriptive design was implemented to perform interviews with 10 individuals with CF and self-reported moderate to severe pain. The interviews explored their pain experiences within five domains: Pain Characteristics, Activities, Relationships, Work/School Life, and Health Care Team. Transcribed interviews underwent a content analysis with team-based constant comparisons. Results: Individuals with CF identify the disease as being painful; express how pain negatively affects all aspects of their lives, including loss of functionality and productivity; and are able to disclose their pain to those with whom they have relationships. Adolescents feel an emotional toll from the loss of socialization as a result of pain and feel their health care team adequately supports their pain. Adults express a unique emotional pain component to CF and feel stigmatized and unsupported by their health care team when asking for pain management solutions. Conclusion: There are differences in how pain is perceived by adolescents and adults with CF that have otherwise not been reported in the current literature. Further explorations of pain across the lifespan and health care provider attitudes toward pain management are needed to guide the development of effective pain management interventions for those with CF. AD - Division of Pulmonary, Critical Care, and Sleep, Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland Department of Acute and Chronic Care, School of Nursing, Johns Hopkins University, Baltimore, Maryland Children's Hospital Vanderbilt, Nashville, Tennessee AN - 131070962. Language: English. Entry Date: 20180807. Revision Date: 20180807. Publication Type: Article AU - Allgood, Sarah J. AU - Kozachik, Sharon AU - Alexander, Kamila A. AU - Thaxton, Abigail AU - Vera, Marc AU - Lechtzin, Noah DB - cin20 DO - 10.1016/j.pmn.2017.11.011 DP - EBSCOhost IS - 4 KW - Cystic Fibrosis -- Complications -- In Adolescence Cystic Fibrosis -- Complications -- In Adulthood Pain -- Etiology Human Adolescence Adult Exploratory Research Descriptive Research Interviews Self Report Content Analysis Socialization Quality of Life Pain -- Complications Pain Management Attitude of Health Personnel Patient Attitudes N1 - research. Journal Subset: Blind Peer Reviewed; Core Nursing; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Pain and Pain Management. NLM UID: 100890606. PY - 2018 SN - 1524-9042 SP - 340-347 ST - Descriptions of the Pain Experience in Adults and Adolescents with Cystic Fibrosis T2 - Pain Management Nursing TI - Descriptions of the Pain Experience in Adults and Adolescents with Cystic Fibrosis UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=131070962&site=ehost-live&scope=site VL - 19 ID - 296 ER - TY - JOUR AB - Aims: To critically synthesize empirical studies on the impact of chronic pain on adolescents' school functioning and school personnel responses to managing pain in schools. Design: Mixed method systematic review. Data sources: Medline, CINAHL, PsycINFO, ERIC, ScienLO, Cochrane Library, and EMBASE were searched for published articles from inception to December 2018. Review methods: Fourteen studies met the inclusion criteria. Data from the qualitative and quantitative studies were synthesized using parallel-results convergent integrated design. The Critical Appraisal Skills Programme and Mixed Methods Appraisal Tool version 2018 were used for assessing the quality of included studies. Results: Chronic pain appears to have a significant negative influence on adolescents' school attendance, academic performance/achievement, academic competence, physical activities, and social functioning. However, other studies indicated that adolescents with chronic pain had better academic performance and competence than healthy peers and that chronic pain did not affect older adolescents' social functioning. There is limited guidelines and resources for how school personnel can help adolescents to manage pain in schools. Conclusion: This review supports the need for future research on the impact of adolescents' chronic pain on the full dimensions of school functioning and to identify the effective responses of school personnel to managing adolescents' pain in schools. Impact: Although findings are somewhat conflicting, overall adolescent's chronic pain appears to have a negative influence on school functioning. Yet limited guidelines exist for how school personnel should respond effectively to manage adolescents' pain in schools. The review indicates the importance of written policies to guide teachers on how to facilitate optimal pain management in schools. It also highlights the significance of clear communication between healthcare professionals and school personnel, adolescents with chronic pain and their parents to support optimal school functioning. AD - School of Nursing and Midwifery, Trinity College Dublin, Dublin, Ireland Nursing College, King Abdulaziz University, Jeddah, Saudi Arabia AN - 145182495. Language: English. Entry Date: 20200826. Revision Date: 20200826. Publication Type: Article AU - Alsaggaf, Fatimah AU - Coyne, Imelda DB - cin20 DO - 10.1111/jan.14404 DP - EBSCOhost IS - 8 KW - Chronic Pain -- In Adolescence School Health -- In Adolescence Academic Performance -- In Adolescence Pain Management -- In Adolescence School Health Services Human Systematic Review Empirical Research Multimethod Studies Medline CINAHL Database Psycinfo Cochrane Library Embase Clinical Competence Physical Activity Adolescence Male Female Funding Source N1 - research; systematic review; tables/charts. Special Interest: Evidence-Based Practice. Grant Information: The first author holds a doctoral scholarship from the King AbdulAziz University, Saudi Arabia.. PY - 2020 SN - 0309-2402 SP - 2005-2022 ST - A systematic review of the impact of chronic pain on adolescents' school functioning and school personnel responses to managing pain in the schools T2 - Journal of Advanced Nursing (John Wiley & Sons, Inc.) TI - A systematic review of the impact of chronic pain on adolescents' school functioning and school personnel responses to managing pain in the schools UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=145182495&site=ehost-live&scope=site VL - 76 ID - 177 ER - TY - JOUR AB - Problem: The absence of facilitating stimuli in the environment in which the adolescent coexists is usually related to a delay in his development. Objective: To analyze the association of factors related to the "Development Delay" diagnostic proposal among adolescents in the school environment. Method: Transversal study performed with 385 adolescents in a city in Northeastern Brazil. The study was approved by the Ethics in Research Committee of the responsible institution, under opinion nº 1.662.528 and the Certificate of Presentation for Ethical Consideration nº 57945016.4.0000.5537. Outcomes: The prevalence of the diagnostic proposition for delay in development was of 18.26%. Related factors that showed significant statistical association were social marginalization, chronic pain, refusal to accept body changes taking place during puberty and psychological trauma. Discussion: One can perceive the relation between the studied variables and human development when considering the literature available. Conclusion: The knowledge of the associated factors most present in this population facilitates the understanding of the diagnostic proposal by the nurse. Besides, it contributes to the identification of the different aspects capable of causing harm to the adolescent and, consequently sequels in the adult life. AD - Federal University of Rio Grande do Norte Federal University of Ceará AN - 148191365. Language: English. Entry Date: 20210122. Revision Date: 20210122. Publication Type: Article AU - Alves Nogueira, Isadora Lorenna AU - Gomes Gabriel, Maynara Caroline AU - Batista Lúcio, Kadyjina Daiane AU - Costa Carino, Ana Carolina AU - de Oliveira Lopes, Marcos Venícios AU - Brandão de Carvalho Lira, Ana Luisa DB - cin20 DO - 10.17665/1676-4285.20206346 DP - EBSCOhost IS - 4 KW - Developmental Disabilities -- Psychosocial Factors -- In Adolescence Adolescent Development Learning Environment Human Adolescence Schools, Elementary -- Brazil Schools, Secondary -- Brazil Brazil Data Analysis Software Fisher's Exact Test Chi Square Test Descriptive Statistics N1 - research; tables/charts. Journal Subset: Double Blind Peer Reviewed; Editorial Board Reviewed; Mexico & Central/South America; Nursing; Peer Reviewed. PY - 2020 SN - 1676-4285 SP - 1-8 ST - Factors related to the "Development Delay" diagnostic proposition among adolescents going to school: transversal study T2 - Online Brazilian Journal of Nursing TI - Factors related to the "Development Delay" diagnostic proposition among adolescents going to school: transversal study UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=148191365&site=ehost-live&scope=site VL - 19 ID - 159 ER - TY - JOUR AB - Aim: The aim of this study was to examine the course of headache diagnosis, headache frequency, anxiety, comorbid depressive symptoms and school absenteeism in adolescents with migraine and tension-type headaches five years after baseline.Methods: We followed a group of 122 children with a mean age of 10.1 (±1.3) years, with headache from a paediatric migraine centre in Paris who had taken part in a previous study from September 2007 to June 2008. This five-year longitudinal study took place in January to June 2012. The measures that were used included demographic variables, headache diagnosis, headache data and a psychological assessment.Results: At the five-year point, about 22% of the children had become headache free, 34% had little to no disability, and 36% had a changed diagnosis. Moreover, a longer history of headache at baseline was associated with a worse evolution of headache at follow-up. Lastly, high depression scores, but not anxiety, were a predictor of more headache disability at follow-up.Conclusion: High depression scores in childhood were a risk factor that was associated with persistence and worsening of headaches in adolescence. This suggests that mental health assessments should be carried out in paediatric headache pain clinics. AD - Family and Development Research Centre, Institute of Psychology, Lausanne Switzerland Paediatric Haematology and Oncology, Armand Trousseau Hospital, Assistance Publique des Hôpitaux de Paris (APHP), Paris France Addictions Unit, Trois Cyprès Hospital, La Penne sur Huveaunne, France Paediatric Migraine Centre, Armand Trousseau Hospital, APHP, Paris France AN - 126133740. Language: English. Entry Date: 20180228. Revision Date: 20181203. Publication Type: journal article AU - Amouroux, Rémy AU - Rousseau‐Salvador, Céline AU - Pillant, Magdeleine AU - Antonietti, Jean‐Philippe AU - Tourniaire, Barbara AU - Annequin, Daniel DB - cin20 DO - 10.1111/apa.13990 DP - EBSCOhost IS - 12 KW - Anxiety -- Complications Absenteeism Migraine -- Etiology Tension Headache -- Etiology Depression -- Complications Male Prospective Studies Adolescence Female Risk Factors Child Human N1 - research; tables/charts. Journal Subset: Biomedical; Continental Europe; Europe; Peer Reviewed. NLM UID: 9205968. PMID: NLM28708256. PY - 2017 SN - 0803-5253 SP - 1961-1965 ST - Longitudinal study shows that depression in childhood is associated with a worse evolution of headaches in adolescence T2 - Acta Paediatrica TI - Longitudinal study shows that depression in childhood is associated with a worse evolution of headaches in adolescence UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=126133740&site=ehost-live&scope=site VL - 106 ID - 331 ER - TY - JOUR AB - PURPOSE: To examine the association between smoking, drunkenness, and medicine use for headache, stomachache, difficulties in getting to sleep, and nervousness in a representative sample of 11- to 15-year-old school-aged children. METHODS: Design: Cross-sectional school-based survey. Setting: A random sample of schools in Denmark in 2002. Participants: All students in the fifth, seventh and ninth grades in these schools, n = 4824. Measurements: Self-reported medicine use for headache, stomachache, difficulties in getting to sleep, and nervousness within the last month; self-reported experience of drunkenness; self-reported smoking. RESULTS: There was a strong and graded association between drunkenness and medicine use, even in models adjusted for the symptom for which the medicine was taken. There was a similar association between medicine use and smoking. CONCLUSIONS: The findings suggest that medicine use can be regarded as part of a cluster of risk behaviors among young people. AD - Department of Social Medicine, University of Copenhagen, Institute of Public Health, Copenhagen, Denmark. anette.andersen@socmed.ku.dk AN - 106371337. Language: English. Entry Date: 20061208. Revision Date: 20200708. Publication Type: Journal Article AU - Andersen, A. AU - Holstein, B. E. AU - Hansen, E. H. DB - cin20 DO - 10.1016/j.jadohealth.2005.12.023 DP - EBSCOhost IS - 3 KW - Alcoholic Intoxication -- In Adolescence Drugs Health Behavior -- In Adolescence Smoking -- In Adolescence Adolescence Anxiety Checklists Child Cluster Sample Confidence Intervals Cross Sectional Studies Data Analysis Software Denmark Female Funding Source Headache Male Odds Ratio Questionnaires Random Sample Schools Self Report Sleep Disorders Human N1 - research; tables/charts. Journal Subset: Allied Health; Nursing; Peer Reviewed; Public Health; USA. Instrumentation: HBSC Symptom Check List (HBSC-SCL). Grant Information: Health Insurance Fund in Denmark (file no. 2003B071). NLM UID: 9102136. PMID: NLM16919797. PY - 2006 SN - 1054-139X SP - 362-366 ST - Is medicine use in adolescence risk behavior? Cross-sectional survey of school-aged children from 11 to 15 T2 - Journal of Adolescent Health TI - Is medicine use in adolescence risk behavior? Cross-sectional survey of school-aged children from 11 to 15 UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106371337&site=ehost-live&scope=site VL - 39 ID - 724 ER - TY - JOUR AB - A survey in the London Borough of Croydon was conducted among an entire school cohort, aged about 9 years, to describe the current morbidity from wheezing illness, its relation to social and family factors, and its effects on social and educational development. A postal screening questionnaire was sent to 5100 parents, and 11.1% of the children were reported to have had wheezing illness over the previous 12 months. A sample of 284 parents were subsequently interviewed at home about their child's illness. School absence over the past year caused by wheezing illness was reported by 58%; and in 12% of children this amounted to more than 30 school days. School absence was strongly associated with all other indicators of morbidity-- short and long term. The proportion described as having "asthma' rose from 22% in those with no absence, to 50% in those with more than 30 days absence. Compared with 92 randomly selected controls with no history of wheezing, wheezy children had more atopic conditions, recurrent headaches, and abdominal pains. School absence was associated with parental separation, non-manual occupation of the mother, more than three children in the household, poor maternal mental health, lack of access to a car, and renting of accommodation. The child's illness had substantial effects on the activities of the mother and the rest of the family, but not on the child's social and recreational activities. Children with over 6 weeks' school absence scored appreciably worse on a teacher's assessment of their social, psychological, and educational adjustment. AN - 66657045. Language: English. Entry Date: 20190505. Revision Date: 20190505. Publication Type: journal article AU - Anderson, H. R. AU - Bailey, P. A. AU - Cooper, J. S. AU - Palmer, J. C. AU - West, S. DB - cin20 DP - EBSCOhost IS - 10 KW - Schools Asthma -- Epidemiology Absenteeism Socioeconomic Factors Asthma -- Complications Child Female Activities of Daily Living England Family Male Respiratory Sounds Reading Human Validation Studies Comparative Studies Evaluation Research Multicenter Studies Questionnaires Short Portable Mental Status Questionnaire Social Readjustment Rating Scale N1 - research. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Instrumentation: Maternal Confidence Questionnaire (MCQ) (Parker and Zahr); Home Observation for Measurement of the Environment (HOME) (Bradley and Caldwell); Short Portable Mental Status Questionnaire (SPMSQ) (Pfeiffer); Defining Issues Test (DIT) (Rest); Social Readjustment Rating Scale (SRRS) (Holmes and Rahe). NLM UID: 0372434. PMID: NLM6639124. PY - 1983 SN - 0003-9888 SP - 777-784 ST - Morbidity and school absence caused by asthma and wheezing illness T2 - Archives of Disease in Childhood TI - Morbidity and school absence caused by asthma and wheezing illness UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=66657045&site=ehost-live&scope=site VL - 58 ID - 861 ER - TY - JOUR AB - Context: Previous researchers have examined factor structures for common concussion symptom inventories. However, they failed to discriminate between the acute (<72 hours) and subacute (3 days-3 months) periods after concussion. The Sport Concussion Assessment Tool (SCAT) is an acute assessment that, when compared with other concussion symptom inventories, includes or excludes symptoms that may result in different symptom factors. Objective: The primary purpose was to investigate the symptom factor structure of the 22-item SCAT symptom inventory in healthy, uninjured and acutely concussed high school and collegiate athletes. The secondary purpose was to document the frequency of the unique SCAT symptom inventory items. Design: Case series. Setting: High school and college. Patients or Other Participants: A total of 1334 healthy, uninjured and 200 acutely concussed high school and collegiate athletes. Main Outcome Measure(s): Healthy, uninjured participants completed the SCAT symptom inventory at a single assessment. Participants in the acutely concussed sample completed the SCAT symptom inventory within 72 hours after concussion. Two separate exploratory factor analyses (EFAs) using a principal component analysis and varimax extraction method were conducted. Results: A 3-factor solution accounted for 48.1% of the total variance for the healthy, uninjured sample: cognitive-fatigue (eg, feeling "in a fog" and "don't feel right"), migraine (eg, neck pain and headache), and affective (eg, more emotional and sadness) symptom factors. A 3-factor solution accounted for 55.0% of the variance for the acutely concussed sample: migraine-fatigue (eg, headache and "pressure in the head"), affective (eg, sadness and more emotional), and cognitive-ocular (eg, difficulty remembering and balance problems) symptom factors. Conclusions: The inclusion of unique SCAT symptom inventory items did not alter the symptom factor structure for the healthy, uninjured sample. For the acutely concussed sample, all but 1 unique SCAT symptom inventory item (neck pain) loaded onto a factor. AD - Department of Kinesiology, Michigan State University, East Lansing Penn Injury Science Center, University of Pennsylvania, Philadelphia Office for Sport Related Concussion, Department of Health, Human Performance and Recreation, University of Arkansas, Fayetteville AN - 147241791. Language: English. Entry Date: 20201201. Revision Date: 20201209. Publication Type: Article AU - Anderson, Morgan AU - Petit, Kyle M. AU - Bretzin, Abigail C. AU - Elbin, R. J. AU - Stephenson, Katie L. AU - Covassin, Tracey DB - cin20 DO - 10.4085/1062-6050-393-19 DP - EBSCOhost IS - 10 KW - Brain Concussion Athletic Injuries Athletes, College Clinical Assessment Tools Human Brain Injuries Checklists Male Female Factor Analysis Child Adolescence Young Adult United States Descriptive Statistics T-Tests Chi Square Test N1 - research; tables/charts. Journal Subset: Allied Health; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Instrumentation: Sport Concussion Assessment Tool (SCAT). NLM UID: 9301647. PY - 2020 SN - 1062-6050 SP - 1046-1053 ST - Sport Concussion Assessment Tool Symptom Inventory: Healthy and Acute Postconcussion Symptom Factor Structures T2 - Journal of Athletic Training (Allen Press) TI - Sport Concussion Assessment Tool Symptom Inventory: Healthy and Acute Postconcussion Symptom Factor Structures UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=147241791&site=ehost-live&scope=site VL - 55 ID - 168 ER - TY - JOUR AB - Aims: To determine obstacles for return-to-work in disability management of low back pain patients sicklisted for 3-4 months.Methods: A cohort of 467 low back pain patients sicklisted for 3-4 months was recruited. A questionnaire was sent to their occupational physicians (OPs) concerning the medical management, obstacles to return-to-work, and the communication with treating physicians.Results: The OPs of 300 of 467 patients participated in this study. In many cases OPs regarded the clinical waiting period (43%), duration of treatment (41%), and view (25%) of the treating physicians as obstacles for return-to-work. Psychosocial obstacles for return-to-work such as mental blocks, a lack of job motivation, personal problems, and conflicts at work were all mentioned much less frequently by OPs. In only 19% of the patients was there communication between OP and treating physician. Communication almost always entailed an exchange of information, and less frequently an attempt to harmonise the management policy. Surprisingly communication was also limited, when OPs felt that the waiting period (32%), duration of treatment (30%), and view (28%) of treating physicians inhibited return-to-work. Communication was significantly associated with the following obstacles for return-to-work: passivity with regard to return-to-work and clinical waiting period; adjusted odds ratios were 3.35 and 2.23, respectively.Conclusions: Medical management of treating physicians is often an obstacle for return to work regarding low back pain patients sicklisted for 3-4 months, in the opinion of OPs. Nevertheless communication between OPs and the treating physicians in disability management of these patients is limited. More attention to prevention of absenteeism and bilateral communication is needed in medical courses. AD - TNO Work and Employment, Netherlands IWI, formerly AS/tri, Netherlands EMGO-Institute and Department of Social Medicine, VU Medical Centre, Amsterdam, Netherlands TNO Work and Employment, PO Box 718, 2130 AS Hoofddorp, Netherlands; h.anema@arbeid.tno.nl AN - 106829938. Language: English. Entry Date: 20030509. Revision Date: 20200708. Publication Type: journal article AU - Anema, J. R. AU - van der Giezen, A. M. AU - Buijs, P. C. AU - van Mechelen, W. AU - Anema, J. R. AU - Van Der Giezen, A. M. AU - Buijs, P. C. AU - Van Mechelen, W. DB - cin20 DO - 10.1136/oem.59.11.729 DP - EBSCOhost IS - 11 KW - Physician Attitudes Low Back Pain -- Rehabilitation Family Practice -- Standards Job Re-Entry Physicians, Family Male Female Adolescence Adult Middle Age Clinical Competence Sick Leave Questionnaires Prospective Studies Interprofessional Relations Occupational Health Services -- Standards Research Subject Recruitment Odds Ratio Confidence Intervals Data Analysis Software Multiple Logistic Regression Human N1 - research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. NLM UID: 9422759. PMID: NLM12409530. PY - 2002 SN - 1351-0711 SP - 729-733 ST - Ineffective disability management by doctors is an obstacle for return-to-work: a cohort study on low back pain patients sicklisted for 3-4 months T2 - Occupational & Environmental Medicine TI - Ineffective disability management by doctors is an obstacle for return-to-work: a cohort study on low back pain patients sicklisted for 3-4 months UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106829938&site=ehost-live&scope=site VL - 59 ID - 791 ER - TY - JOUR AB - This study aimed to explore the experiences of adolescents from Singapore, aged 10–18 years old, living with cancer and their perceptions on how their psychosocial outcomes can be improved. A descriptive qualitative study design was used. Convenience sampling was used to recruit 10 participants from a pediatric oncology ward in a Singapore hospital. Individual semi-structured interviews were conducted. Thematic analysis was used to analyze the data. Five major themes emerged: (1) experience of physical symptoms, (2) emotional response to their condition, (3) changes in social dynamics, and (4) falling behind in academics. The psychosocial outcomes of Singaporean adolescents with cancer could be improved by thorough pain assessments and creating a more conducive hospital environment. AD - Division of Nursing, KK Women's and Children's Hospital, Singapore, Singapore Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore KK Women's and Children's Hospital, Singapore, Singapore AN - 133531565. Language: English. Entry Date: 20181217. Revision Date: 20181231. Publication Type: Article AU - Ang, Sin Hui AU - Koh, Serena Siew Lin AU - Lee, Xiu Hua Hideka Tamamura AU - Shorey, Shefaly DB - cin20 DO - 10.1177/1367493518763109 DP - EBSCOhost IS - 4 KW - Cancer Patients -- Psychosocial Factors -- In Adolescence Patient Attitudes Psychological Well-Being Adolescent Health Human Funding Source Singapore Male Female Child Adolescence Descriptive Research Qualitative Studies Convenience Sample Semi-Structured Interview Thematic Analysis Academic Failure Emotions Pain Measurement Health Facility Environment Audiorecording Triangulation Audit Trail Open-Ended Questionnaires Interview Guides Chemotherapy, Cancer -- Adverse Effects Cancer Pain Cancer Fatigue Interpersonal Relations Family Relations Support, Psychosocial Social Behavior N1 - research; tables/charts. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Nursing; Peer Reviewed; UK & Ireland. Grant Information: This work was supported by the National University of Singapore.. NLM UID: 9806360. PY - 2018 SN - 1367-4935 SP - 532-544 ST - Experiences of adolescents living with cancer: A descriptive qualitative study T2 - Journal of Child Health Care TI - Experiences of adolescents living with cancer: A descriptive qualitative study UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=133531565&site=ehost-live&scope=site VL - 22 ID - 277 ER - TY - JOUR AB - Headache is one of the most common disorders in childhood, with an estimated 75% of children reporting significant headache by the age of 15 years. Pediatric migraine is the most frequent recurrent headache disorder, occurring in up to 28% of older teenagers. Headaches rank third among the illness-related causes of school absenteeism and result in substantial psychosocial impairment among pediatric patients. The aim of this study was to clarify the evolution of the clinical features of primary headache in the transition from childhood to adulthood through a review of relevant data available in the PubMed and Google Scholar databases for the period 1988 to July 2013. The search strategy identified 15 published articles which were considered eligible for inclusion in the analysis (i.e. relevant to the investigation of pediatric headache outcome). All were carried out after the publication of the first version of the International Classification of Headache Disorders (ICHD-I). The availability of data on the evolution of primary headaches over a period of time is important from both a clinical and a public health perspective. The identification of prognostic factors of the evolution of headache (remission or evolution into another headache form) over time should be an objective of future headache research for the development of prevention strategies. Given that headache is a major factor contributing to school absenteeism and poorer quality of life not only in childhood but also in adolescence, understanding the natural history and the management of the different headache forms is vital for our future. AD - Headache Center, C. Mondino National Institute of Neurology Foundation, IRCCS, University of Pavia, Pavia, Italy. State Medical and Pharmaceutical University “Nicolae Testemitanu”, Chișinău, Republic of Moldova.; University of Pavia, Pavia, Italy. C. Mondino National Institute of Neurology Foundation, IRCCS, Pavia, Italy. Department of Neurology, Mersin University School of Medicine, Mersin, Turkey. Headache Center, C. Mondino National Institute of Neurology Foundation, IRCCS, University of Pavia, Pavia, Italy.; Child Neurology and Psychiatry Department, C. Mondino National Institute of Neurology Foundation, IRCCS, University of Pavia, Pavia, Italy. AN - 109694508. Language: English. Entry Date: 20140228. Revision Date: 20150923. Publication Type: Journal Article. Journal Subset: Biomedical AU - Antonaci, Fabio AU - Voiticovschi-Iosob, Cristina AU - Di Stefano, Anna Luisia AU - Galli, Federica AU - Ozge, Aynur AU - Balottin, Umberto DB - cin20 DO - 10.1186/1129-2377-15-15 DP - EBSCOhost IS - 1 N1 - Continental Europe; Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. Special Interest: Pain and Pain Management. NLM UID: 100940562. PY - 2014 SN - 1129-2369 SP - 1-11 ST - The evolution of headache from childhood to adulthood: a review of the literature T2 - Journal of Headache & Pain TI - The evolution of headache from childhood to adulthood: a review of the literature UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=109694508&site=ehost-live&scope=site VL - 15 ID - 500 ER - TY - JOUR AB - Background Children living with juvenile idiopathic arthritis (JIA) have swollen, painful and stiff joints, which may have an impact on all spheres of their life, as well as their family. While children diagnosed in their preschool years may be at risk for worse physical outcomes than children diagnosed later in life, it is not clear whether they have worse psychological outcomes and whether these outcomes have an impact on their everyday life. The aim of this study was to examine the association between age at diagnosis and health outcomes in families of children with JIA. Methods Parents of children with JIA ( n = 182) who attended rheumatology clinics at the Montreal Children's Hospital and British Columbia Children's Hospital completed measures assessing socio-demographic attributes, their child's health status, health-related quality of life and pain level, as well as their own level of psychological distress and coping behaviours. Regression models explored the association between age at diagnosis and health outcomes while adjusting for sex, age, severity and duration of the disease. Results Parents of children diagnosed with JIA before 5 years of age found their child to have a better health-related quality of life in terms of psychosocial functioning than parents of children diagnosed later [β = −0.91 (−1.63, −0.19)]. Children diagnosed younger were also found to be less limited in schoolwork or activities with friends because of emotional or behavioural problems than children diagnosed later [odds ratio = 0.07 (0.01, 0.42)]. Conclusions Children diagnosed younger seem to show good psychosocial adjustment, which may also be true for their caregivers. Perhaps more attention to psychosocial adjustment should be given to families of children who are diagnosed with the disease at an older age. AD - Department of Epidemiology and Community Medicine, University of Ottawa; Centre for Global Health, Institute of Population Health, University of Ottawa, Ottawa, ON Département de médecine sociale et préventive and Institut de recherche en santé publique de l'Université de Montréal (IRSPUM), Université de Montréal and Department of Occupational Therapy, Montreal Children's Hospital of the McGill University Health Centre École de Réadaptation and Institut de recherche en santé publique de l'Université de Montréal (IRSPUM), Université de Montréal, Centre de recherche interdisciplinaire en réadaptation (CRIR), Montreal, QC, Canada AN - 104266958. Language: English. Entry Date: 20130412. Revision Date: 20200708. Publication Type: Journal Article AU - April, K. Toupin AU - Cavallo, S. AU - Feldman, D. Ehrmann DB - cin20 DO - 10.1111/j.1365-2214.2012.01386.x DP - EBSCOhost IS - 3 KW - Arthritis, Juvenile Rheumatoid -- Diagnosis Health Status -- In Infancy and Childhood Age Factors -- In Infancy and Childhood Psychological Well-Being -- In Infancy and Childhood Human Canada Funding Source Child, Preschool Child Child Health Adolescence Adolescent Health Child, Disabled Quality of Life -- Evaluation Pain Measurement Stress, Psychological Parents of Disabled Children Adult Coping Descriptive Statistics Arthritis, Juvenile Rheumatoid -- Psychosocial Factors Psychosocial Aspects of Illness Odds Ratio Child Behavior Disorders Adaptation, Psychological Symptom Checklist-90-Revised Questionnaires Psychological Tests Reliability and Validity Summated Rating Scaling T-Tests Chi Square Test Multivariate Analysis Regression Logistic Regression Linear Regression Confidence Intervals Male Female Severity of Illness -- Evaluation N1 - research; tables/charts. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Pediatric Care; Psychiatry/Psychology. Instrumentation: Symptom Checklist-90-Revised (SCL-90-R); Child Health Questionnaire (CHQ-PF50); Juvenile Arthritis Quality of Life Questionnaire (JAQQ) (Duffy et al); Child Health Inventory for parents (CHIP) (McCubbin et al); Economic Hardship Questionnaire. Grant Information: This study was funded by the Canadian Institutes of Health Research, the Sick Kids Foundation, the Canadian Arthritis Network and the Arthritis Society of Canada.. NLM UID: 7602632. PMID: NLM22676178. PY - 2013 SN - 0305-1862 SP - 442-448 ST - Children with juvenile idiopathic arthritis: are health outcomes better for those diagnosed younger? T2 - Child: Care, Health & Development TI - Children with juvenile idiopathic arthritis: are health outcomes better for those diagnosed younger? UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104266958&site=ehost-live&scope=site VL - 39 ID - 524 ER - TY - JOUR AB - Background: A scarcity of studies on the role of resilience resources (RRs) and vulnerability risk (VR) in children and adolescents with primary headache hampers the development of a risk‐resilience model for pediatric headaches. Objective: To examine the extent to which headache frequency and diagnosis are associated with RRs and VR and explore possible predictors of low RRs and high VR in a cross‐sectional population‐based study in adolescents. Methods: This is a cross‐sectional population study conducted in a small city in Brazil (Delfinópolis). Consents and analyzable data were obtained from 339/378 adolescents (89.7%). RRs and VR were assessed using the validated Brazilian version of the Resiliency Scales for Children and Adolescents, completed by the adolescents. Parents filled a structured questionnaire assessing sociodemographic and headache characteristics, as well as the Brazilian‐validated version of the Strengths and Difficulties Questionnaire added to the impact supplement to evaluate the adolescent's psychosocial adjustment skills. Teachers completed a structured questionnaire about the students' school performance. Results: A higher frequency of headache was associated with lower RRs (F3,335 = 2.99, p = 0.031) and higher VR (F3,335 = 4.05, p = 0.007). Headache diagnosis did not significantly influence the risk of having lower RRs or higher VR. In the exploratory analyses, females (OR 3.07; 95% CI: 1.16–9.3) and individuals with psychosocial adjustment problems (OR 7.5; 95% CI: 2.51–22.4) were predictors of low RRs, and prenatal exposure to tobacco (OR 5.6; 95% CI: 1.57–20.9) was a predictor of high VR in adolescents with primary headache. Conclusions: The risk of low RRs and high VR was associated with a higher headache frequency, but not with headache diagnosis. These findings may contribute to the development of a risk‐resilience model of headaches in the pediatric population and help identify novel targets and develop effective resources for successful interventions. AD - Department of Neuroscience, Glia Institute, Ribeirão Preto, Brazil Department of Neuroscience and Behavioral Sciences, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil Department of Psychology, Pontifical Catholic University, Rio de Janeiro, Brazil Ventus Therapeutics, Montreal QC,, Canada AN - 149452519. Language: English. Entry Date: 20210329. Revision Date: 20210401. Publication Type: Article AU - Arruda, Marco Antônio AU - Arruda, Renato AU - Landeira‐Fernandez, J. AU - Anunciação, Luis AU - Bigal, Marcelo Eduardo DB - cin20 DO - 10.1111/head.14078 DP - EBSCOhost IS - 3 KW - Headache -- In Adolescence Hardiness Vulnerability Risk Assessment Human Cross Sectional Studies Adolescence Brazil Scales Questionnaires Exploratory Research Descriptive Statistics Odds Ratio Confidence Intervals Male Female Sex Factors N1 - research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. Instrumentation: Resiliency Scales for Children and Adolescents [Brazil]. NLM UID: 2985091R. PY - 2021 SN - 0017-8748 SP - 546-557 ST - Resilience and vulnerability in adolescents with primary headaches: A cross‐sectional population‐based study T2 - Headache: The Journal of Head & Face Pain TI - Resilience and vulnerability in adolescents with primary headaches: A cross‐sectional population‐based study UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=149452519&site=ehost-live&scope=site VL - 61 ID - 144 ER - TY - JOUR AB - OBJECTIVES: To conduct a population-based study describing school performance in children with episodic migraine (EM), chronic migraine (CM), and probable migraine (PM), relative to controls. METHODS: Children (n = 5,671) from 87 cities and 18 Brazilian states were interviewed by their teachers (n = 124). First, teachers were asked to provide information on the performance of the students while at school, which consisted of the same information provided to the educational board, with measurements of the overall achievement of competencies for the school year. The MTA-SNAP-IV scale was then used to capture symptoms of attention-deficit/hyperactivity disorder, and to provide objective information on the performance of the students. Parents were interviewed using a validated headache questionnaire and the Strengths and Difficulties Questionnaire, which measures behavior in 5 domains. Multivariate models estimated determinants of school performance as a function of headache status. RESULTS: EM occurred in 9% of the children, PM in 17.6%, and CM in 0.6%. Poor performance at school was significantly more likely in children with EM and CM, relative to children without headaches, and was significantly influenced by severity (p < 0.001) and duration (p < 0.001) of headache attacks, by abnormal scores of mental health (p < 0.001), and by nausea (p < 0.001), as well as by headache frequency, use of analgesics, and gender. CONCLUSION: Children with migraine are at an increased risk of having impairments in their school performance and factors associated with impairment have been mapped. Future studies should address the directionality of the association and putative mechanisms to explain it. AD - From the Glia Institute (M.A.A.), Ribeirao Preto, SP, Brazil; Global Center for Scientific Affairs, Office of the Chief Medical Officer (M.E.B.), Merck & Co., Inc., West Point, PA; and Department of Neurology (M.E.B.), Albert Einstein College of Medicine, Bronx, NY. AN - 108074098. Language: English. Entry Date: 20130201. Revision Date: 20150712. Publication Type: Journal Article AU - Arruda, M. A. AU - Bigal, M. E. DB - cin20 DO - 10.1212/WNL.0b013e318271f812 DP - EBSCOhost IS - 18 KW - Educational Status Headache -- Epidemiology Migraine -- Classification Migraine -- Epidemiology Tension Headache -- Epidemiology Child Child, Preschool Female Headache -- Classification Human Male Questionnaires -- Standards Risk Factors Severity of Illness Indices Tension Headache -- Classification Questionnaires N1 - research. Journal Subset: Biomedical; Peer Reviewed; USA. Instrumentation: Strengths and Difficulties Questionnaire (SDQ). NLM UID: 0401060. PMID: NLM23109652. PY - 2012 SN - 0028-3878 SP - 1881-1888 ST - Migraine and migraine subtypes in preadolescent children: Association with school performance T2 - Neurology TI - Migraine and migraine subtypes in preadolescent children: Association with school performance UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=108074098&site=ehost-live&scope=site VL - 79 ID - 544 ER - TY - JOUR AB - Objectives Primary headache syndromes (eg, migraine and tension-type headache [TTH]) and attention-deficit/hyperactivity disorder (ADHD) are prevalent in childhood and may cause impairment in social and academic functioning. We tested if ADHD or its symptoms are associated with specific headache syndromes or with headache frequency. Study design Cross-sectional epidemiological study with direct interviews to parents and teachers using validated and standardized questionnaires. Setting Populational study. Participants Children aged 5 to 11 years (n = 1856). Outcome measures Prevalence of ADHD as a function of headache status in crude and adjusted analyses. Results The prevalence of migraine was 3.76%. Infrequent episodic TTH occurred in 2.3% of the sample, and frequent episodic TTH occurred in 1.6%. The prevalence of ADHD was 6.1%. The prevalence of ADHD was not significantly different by headache category. For hyperactivity-impulsivity symptoms, the prevalence was 8.1% in children without headache, 23.7% in children with migraine (relative risk [RR], 2.6; 95% confidence interval [CI], 1.6-4.2), and 18.4% in children with probable migraine (RR, 2.1; 95% CI, 1.4-3.2). For inattention, no significant differences were seen. In multivariate analyses, ADHD or inattention symptoms were not predicted by headache subtypes or headache frequency. Hyperactivity-impulsivity symptoms were significantly associated with any headache (P < 0.01), TTH (P < 0.01), or migraine (P < 0.001). Conclusion Migraine and TTH are not comorbid to ADHD overall, but are comorbid to hyperactive-impulsive behavior. Providers and educators should be aware of the association. AD - Director, Glia Institute, Braz Olaia Acosta, 727, s. 310, Ribeirao Preto, Sao Paulo, Brazil, 14026-040. arruda@institutoglia.com.br. AN - 105105477. Language: English. Entry Date: 20101119. Revision Date: 20150711. Publication Type: Journal Article AU - Arruda, M. A. AU - Guidetti, V. AU - Galli, F. AU - Albuquerque, R. C. AU - Bigal, M. E. DB - cin20 DO - 10.3810/pgm.2010.09.2197 DP - EBSCOhost IS - 5 KW - Attention Deficit Hyperactivity Disorder -- Epidemiology Migraine -- Epidemiology Tension Headache -- Epidemiology Age Factors Brazil Child Child, Preschool Cross Sectional Studies Female Human Behavior -- Epidemiology Income Male Multivariate Analysis Prevalence Sex Factors N1 - research. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 0401147. PMID: NLM20861584. PY - 2010 SN - 0032-5481 SP - 18-26 ST - Migraine, tension-type headache, and attention-deficit/hyperactivity disorder in childhood: a population-based study T2 - Postgraduate Medicine TI - Migraine, tension-type headache, and attention-deficit/hyperactivity disorder in childhood: a population-based study UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105105477&site=ehost-live&scope=site VL - 122 ID - 618 ER - TY - JOUR AB - Purpose: Shoulder problems are frequent among senior elite handball players. The objective of this study was to assess the prevalence of shoulder problems among adolescent elite handball players and to investigate potential differences in gender, school grade, playing position and playing level.Methods: During the 2014 and 2015 pre-season periods, 471 players (age 15-18 years, 54% female) completed a comprehensive baseline questionnaire regarding history of any shoulder pain and shoulder problems experienced during the past season. The players were monitored weekly for one competition season (September-April) regarding shoulder problems and the amount of match and training. Generalised linear models with a binomial link function were used to calculate a prevalence ratio (PR) with 95% confidence interval (CI) to compare the subgroups of players.Results: In total, 110 players (23%) reported having substantial shoulder problems (defined as moderate/severe reduction in training volume, or moderate/severe reduction in performance, or complete inability to participate) at some point during the follow-up season, of which almost half reported complete inability to participate. Of those players reporting substantial problems, 43% (95% CI 39-48) did so for at least 3 consecutive weeks during the season. The prevalence was significantly higher in female players (PR 1.46, 95% 1.04-2.06) and in backcourt players (PR 1.58, 95% CI 1.08-2.32), but no differences were found for school grade (PR 1.21 95% CI 0.88-1.67) or playing level (PR 1.09 95% CI 0.76-1.56).Conclusions: The prevalence of substantial shoulder problems in adolescent elite handball players is high, especially among females, and this warrants further studies on risk factors for shoulder injury and the development of prevention strategies in handball players already before the age of 15. These findings also highlight the importance of introducing a clinical monitoring programme on a routine basis and improving the medical support, taking gender-related aspects into consideration, at handball-profiled secondary schools.Level Of Evidence: II. AD - Musculoskeletal and Sports Injury Epidemiology Center, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden Naprapathögskolan-Scandinavian College of Naprapathic Manual Medicine, Stockholm, Sweden Department of Monitoring and Evaluation, Public Health Agency of Sweden, Solna, Sweden Division of Community Medicine, Department of Medical and Health Sciences, Linköping University, Linköping, Sweden Department of Orthopaedics, Hässleholm-Kristianstad-Ystad Hospitals, Hässleholm, Sweden AN - 130553142. Language: English. Entry Date: In Process. Revision Date: 20190701. Publication Type: journal article AU - Asker, Martin AU - Holm, Lena W. AU - Källberg, Henrik AU - Waldén, Markus AU - Skillgate, Eva DB - cin20 DO - 10.1007/s00167-018-4857-y DP - EBSCOhost IS - 7 KW - Athletic Injuries -- Epidemiology Prevalence Retrospective Design Female Male Human Risk Factors Shoulder Sports Shoulder Joint -- Injuries Disease Susceptibility Shoulder Pain -- Etiology Sweden Adolescence Validation Studies Comparative Studies Evaluation Research Multicenter Studies Scales N1 - research. Journal Subset: Biomedical; Blind Peer Reviewed; Continental Europe; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. Instrumentation: Clinical Decision Making in Nursing Scale (CDMNS) (Jenkins). Grant Information: CIF 2015/11, CIF 2016/6//Centrum for Idrottsforskning/. NLM UID: 9314730. PMID: NLM29427220. PY - 2018 SN - 0942-2056 SP - 1892-1900 ST - Female adolescent elite handball players are more susceptible to shoulder problems than their male counterparts T2 - Knee Surgery, Sports Traumatology, Arthroscopy TI - Female adolescent elite handball players are more susceptible to shoulder problems than their male counterparts UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=130553142&site=ehost-live&scope=site VL - 26 ID - 301 ER - TY - JOUR AB - Objective: This is a descriptive study to determine patient satisfaction of pain relief exercises in trauma patients.Material and Methods: The study group consisted of patients who presented with trauma to the emergency units of two hospitals in Istanbul. A total of 418 patients aged 18-65 years were included. A 13-item individual properties form, shortened wound assessment with visual analog scale and forth section of McGill-Melzack pain question form were used to collect data. Data were expressed as percentage, median, and standart deviation, and One-way Anova Test, Student's t Test, and Pearson Corelation Analysis methods were used for statistical analyses.Results: Of the patients, 25.4% (n= 106) was in the 28-37 years age range, 69.9% (n= 292) was male, 70.8% (n= 296) was graduate of elementary school, 44.5% (n= 186) was self-employed, 94.5% (n= 395) had blunt trauma and 75.4% (n= 315) had limb trauma. All (n= 418) patients were administered nonsteroid antiinflammatory drugs; 95.5% (n= 416) by intramuscular injection; in 62.9% (n= 293) the paint did not relieve.Conclusion: The pain perceived after trauma until interview time was defined as 'very severe' by 51.7% (n= 216) of the patients. The pain relief exercises were considered not satisfactory by 63.4% (n= 265) of the cases; the degree of satisfaction for patient care in the emergency unit was medium (4.35 +/- 2.78; 5.18 +/- 2.07). As a result, pain severity increased parallel to trauma severity and the degree of satisfaction for pain relief exercises and emergency care for patients who had very severe pain severity was low.The data obtained suggest that pain is still not managed as a serious problem in the emergency trauma units and that most trauma patients are not satisfied with the emergency care and pain relieving approaches. AN - 105865636. Language: Turkish. Entry Date: 20080321. Revision Date: 20150711. Publication Type: Journal Article AU - Aslan, F. E. AU - Aygin, D. AU - Sariyildiz, D. DB - cin20 DP - EBSCOhost IS - 5 KW - Pain -- Therapy Patient Satisfaction Trauma -- Complications Adolescence Adult Aged Antiinflammatory Agents, Non-Steroidal -- Therapeutic Use Descriptive Research Descriptive Statistics Emergency Service Female Male McGill Pain Questionnaire Middle Age One-Way Analysis of Variance Pain -- Drug Therapy Pearson's Correlation Coefficient Questionnaires T-Tests Visual Analog Scaling Human N1 - abstract; equations & formulas; research; tables/charts. Journal Subset: Biomedical; Middle East; Peer Reviewed. Instrumentation: McGill Pain Questionnaire; Forth section of McGill-Melzack pain question form. PY - 2007 SN - 1300-0292 SP - 687-694 ST - The satisfaction level of patients with trauma on pain management T2 - Turkiye Klinikleri Journal of Medical Sciences TI - The satisfaction level of patients with trauma on pain management UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105865636&site=ehost-live&scope=site VL - 27 ID - 701 ER - TY - JOUR AB - One of the most common problems in children that pain can not be managed adequately by the health workers. Knowledge level of nurses is an important factor in effective pain management. This study was designed to determine intern nursing students' level of pediatric pain management knowledge (PPMK) and the affecting factors. The study used a descriptive, comparative, correlational, and cross-sectional design. Research was conducted at a Nursing School of a State University. The study was carried out on 72 pediatric nursing internship students. Data were collected using a demographic data form for affecting factors such as grade point averages, age, gender, previous pain education, and self-sufficiency, and a pain management knowledge questionnaire consisting of six subdimensions: awareness of pain, pain physiopathology, barriers to pain management, pain diagnosis, pain assessment, and pain control. Data were analyzed using quartiles, correlation, regression analysis, and the Structural Equation Model. The mean age of the participants was 22.64 ± 1.02, and 63.9% of them self-evaluated their current knowledge as inadequate. The PPMK score was 67.58 ± 7.37 and the students got medium level scores from the overall subdimensions. On the other hand, they got the lowest scores from the pain control (29.35 ± 4.29) and the highest scores from the pain assessment (5.49 ± 1.55). A moderate level of significant relationship was found in the Structural Equation Model (p <.05). The students were determined to have a moderate PPMK level and get the lowest scores, particularly from the pain control. AD - Faculty of Nursing, Dokuz Eylul University, Inciraltı, Izmir, Turkey AN - 143365212. Language: English. Entry Date: 20200527. Revision Date: 20200528. Publication Type: Article AU - Aydın, Bahise AU - Bektaş, Murat DB - cin20 DO - 10.1016/j.pmn.2019.06.012 DP - EBSCOhost IS - 3 KW - Pediatric Care Pain Management Nursing Knowledge Interns and Residents Students, Nursing Human Descriptive Research Comparative Studies Correlational Studies Cross Sectional Studies Age Factors Sex Factors Pain -- Education Questionnaires Pain -- Physiology Pain -- Diagnosis Pain Measurement Regression Structural Equation Modeling Descriptive Statistics Adult Data Analysis Software Educational Status Content Validity Pilot Studies Kuder-Richardson Coefficient Internal Consistency Socioeconomic Factors N1 - research; tables/charts. Journal Subset: Blind Peer Reviewed; Core Nursing; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Instrumentation: Pain Management Knowledge Questionnaire. NLM UID: 100890606. PY - 2020 SN - 1524-9042 SP - 290-298 ST - Pediatric Pain Management Knowledge Levels of Intern Nursing Students T2 - Pain Management Nursing TI - Pediatric Pain Management Knowledge Levels of Intern Nursing Students UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=143365212&site=ehost-live&scope=site VL - 21 ID - 186 ER - TY - JOUR AB - In addition to its high frequency and relevant individual and social impact, chronic pain (CP) has been shown to be a major contributor to increased healthcare utilisation, reduced labour productivity, and consequently large direct and indirect costs. In the context of a larger nationwide study, we aimed to assess the total annual direct and indirect costs associated with CP in Portugal. A population-based study was conducted in a representative sample of the Portuguese adult population. The 5,094 participants were selected using random digit dialling and contacted by computer-assisted telephone interviews. Questionnaires included the brief pain inventory and pain disability index. Estimates were adequately weighted for the population. From all CP subjects identified, a subsample (n = 562) accepted to participate in this economic study. Mean total annualised costs per CP subject of €1,883.30 were observed, amounting to €4,611.69 million nationally, with 42.7% direct and 57.3% indirect costs, and corresponding to 2.71% of the Portuguese annual GDP in 2010. Only socio-demographic variables were significantly and independently associated with CP costs, and not CP severity, raising the possibility of existing inequalities in the distribution of healthcare in Portugal. The high economic impact of CP in Portugal was comprehensively demonstrated. Given the high indirect costs observed, restricting healthcare services is not a rational response to these high societal costs; instead improving the quality of CP prevention and management is recommended. AD - Centro Nacional de Observação em Dor (OBSERVDOR, Portuguese National Pain Observatory), Porto Portugal Department of Health Information and Decision Sciences (CIDES), Faculty of Medicine, University of Porto, Rua Dr. Plácido da Costa, s/n, 4200-319, Porto, Portugal Centre for Research in Health Technologies and Information Systems (CINTESIS), University of Porto, Porto, Portugal Centro Nacional de Observação em Dor (OBSERVDOR, Portuguese National Pain Observatory), Porto, Portugal Department of Experimental Biology, Faculty of Medicine, University of Porto, Porto, Portugal Institute for Molecular and Cell Biology (IBMC), University of Porto, Porto, Portugal AN - 112155900. Language: English. Entry Date: 20180720. Revision Date: 20190308. Publication Type: journal article AU - Azevedo, Luís AU - Costa-Pereira, Altamiro AU - Mendonça, Liliane AU - Dias, Cláudia AU - Castro-Lopes, José AU - Azevedo, Luís Filipe AU - Mendonça, Liliane AU - Dias, Cláudia Camila AU - Castro-Lopes, José M. DB - cin20 DO - 10.1007/s10198-014-0659-4 DP - EBSCOhost IS - 1 KW - Economic Aspects of Illness Disabled -- Statistics and Numerical Data Chronic Pain -- Economics Health Services -- Utilization Socioeconomic Factors Retirement -- Economics Female Models, Statistical Adolescence Middle Age Male Portugal Young Adult Absenteeism Health Services -- Economics Adult Cross Sectional Studies Aged Health Care Costs -- Statistics and Numerical Data Brief Pain Inventory Questionnaires Human N1 - research. Journal Subset: Biomedical; Continental Europe; Double Blind Peer Reviewed; Europe; Health Services Administration; Peer Reviewed. Instrumentation: Brief Pain Inventory (BPI). NLM UID: 101134867. PMID: NLM25416319. PY - 2016 SN - 1618-7598 SP - 87-98 ST - The economic impact of chronic pain: a nationwide population-based cost-of-illness study in Portugal T2 - European Journal of Health Economics TI - The economic impact of chronic pain: a nationwide population-based cost-of-illness study in Portugal UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=112155900&site=ehost-live&scope=site VL - 17 ID - 431 ER - TY - JOUR AB - Objective: To characterize and assess the prevalence of chronic gynecologic pain and, more specifically, chronic vulvar pain.Study Design: A questionnaire was mailed to women aged 18-80 years who were ambulatory patients at an academic multidisciplinary practice. Quality of life, health history, obstetric and gynecologic history, and pain symptoms were assessed.Results: Of the 4,872 surveys mailed to deliverable addresses, 36.8% were returned. The population was primarily Caucasian (83%), with an average age of 50.2 years. Approximately 4% of respondents reported a history of vulvar pain in the 6 months preceding the survey, and 17% reported other types of chronic gynecologic pain. Women reporting vulvar and nonvulvar pain were 2 times as likely as asymptomatic women to report a history of depression and vaginal infections, a poorer quality of life (p < 0.001) and greater stress. Dyspareunia and pain with daily activities were reported more frequently by women with vulvar pain than by women with non-vulvar gynecologic pain.Conclusion: The prevalence of vulvar pain in this study was lower than previously reported. Chronic gynecologic pain, and vulvar pain in particular, affects quality of life on both intimate and social levels. Self-reported stress and vaginal infections were the strongest correlates of chronic vulvar pain. AD - Department of Obstetrics and Gynecology, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, New Brunswick, USA Department of Obstetrics and Gynecology, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, New Brunswick, USA. gloria.bachmann@umdnj.edu AN - 106262847. Language: English. Entry Date: 20070406. Revision Date: 20161114. Publication Type: journal article AU - Bachmann, G. A. AU - Rosen, R. AU - Arnold, L. D. AU - Burd, I. AU - Rhoads, G. G. AU - Leiblum, S. R. AU - Avis, N. AU - Bachmann, Gloria A. AU - Rosen, Raymond AU - Arnold, Lauren Denise AU - Burd, Irina AU - Rhoads, George G. AU - Leiblum, Sandra R. AU - Avis, Nancy DB - cin20 DP - EBSCOhost IS - 1 KW - Chronic Pain -- Etiology Genital Diseases, Female Vulvar Diseases Academic Medical Centers Adolescence Adult Aged Aged, 80 and Over Chronic Pain -- Psychosocial Factors Confidence Intervals Data Analysis Software Depression -- Etiology Descriptive Statistics Female Funding Source Logistic Regression Middle Age Odds Ratio Prevalence Quality of Life Questionnaires Self Report Stress, Psychological Surveys Univariate Statistics Vaginitis -- Complications Vulvar Diseases -- Psychosocial Factors Vulvar Diseases -- Risk Factors Human N1 - research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Instrumentation: Ladder of Life Quality of Life (QOL). Grant Information: R01 HD040119/HD/NICHD NIH HHS/United States. NLM UID: 0173343. PMID: NLM16482769. PY - 2006 SN - 0024-7758 SP - 3-9 ST - Chronic vulvar and other gynecologic pain: prevalence and characteristics in a self-reported survey T2 - Journal of Reproductive Medicine® TI - Chronic vulvar and other gynecologic pain: prevalence and characteristics in a self-reported survey UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106262847&site=ehost-live&scope=site VL - 51 ID - 738 ER - TY - JOUR AB - OBJECTIVES: Frequent hospitalizations for sickle cell disease (SCD) vaso-occlusive crises (VOCs) are associated with school absenteeism, emotional distress, and financial hardships. Our goal was to decrease hospital days for VOC admissions by 40% over a 5-year period. METHODS: From October 2011 to September 2016, a multidisciplinary quality-improvement project was conducted with a plan-do-study-act methodology. Five key drivers were identified and 9 interventions implemented. Interventions included individualized home pain plans, emergency department and inpatient order sets, an inpatient daily schedule, psychoeducation, and a biofeedback program. High users ($4 admissions per year) received an individualized SCD plan and assigned mental health provider. We expanded the high-use group to include atrisk patients (3 admissions per year). Data were analyzed for patients ages 0 to 21 years admitted for VOC. Hospital days were the primary measure; the 30-day readmission rate was the balancing measure. RESULTS: A total of 216 SCD pediatric patients were managed in 2011 with a 14% increase over 5 years. A total of 122 patients were admitted for VOC. Hospital days decreased by 61% from 59.6 days per month in the preintervention period to 23.2 days per month in the postintervention period (P, .0001). Length of stay decreased from 4.78 (SD = 4.08) to 3.84 days (SD = 2.10; P = .02). Among high users, hospital days decreased from 35.4 to 15.5 days per month. The thirty-day readmission rate decreased from 33.9% to 19.4%. Overall savings in direct hospital costs per year were $555 120. CONCLUSIONS: A dedicated team effort with simple interventions can have a significant impact on the well-being of a patient population and hospital costs. AD - Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut AN - 136246614. Language: English. Entry Date: 20190508. Revision Date: 20190510. Publication Type: Article AU - Balsamo, Lyn AU - Shabanova, Veronika AU - Carbonella, Judith DB - cin20 DO - 10.1542/peds.2018-2218 DP - EBSCOhost IS - 5 KW - Anemia, Sickle Cell Vascular Diseases Quality Improvement Pediatric Care Multidisciplinary Care Team Length of Stay Patient Admission Research, Interdisciplinary Home Health Care Emergency Service Psychoeducation Biofeedback Infant, Newborn Infant Child, Preschool Child Adolescence Young Adult Human N1 - research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 0376422. PY - 2019 SN - 0031-4005 SP - 1-8 ST - Improving Care for Sickle Cell Pain Crisis Using a Multidisciplinary Approach T2 - Pediatrics TI - Improving Care for Sickle Cell Pain Crisis Using a Multidisciplinary Approach UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=136246614&site=ehost-live&scope=site VL - 143 ID - 247 ER - TY - JOUR AB - The purpose of this open-label study was to compare rizatriptan with usual non-triptan therapy for migraine in patients who had never received a triptan. Patient-reported outcomes were examined for a prestudy migraine attack and after three consecutive study attacks, the first and third treated with rizatriptan 10 mg wafer and the second with usual non-triptan therapy. A total of 97 patients (83% women; mean age 39 years) completed the study. Two-thirds of patients reported severe or total disability during migraine attacks. All comparisons between rizatriptan therapy and usual non-triptan therapy significantly favoured rizatriptan (p < or = 0.01). Headache relief by 2 hours was reported by 78-83% of patients after rizatriptan and by 46-48% of patients after usual therapy; 41-47% and 12-18%, respectively, were pain free at 2 hours. Patient satisfaction and migraine-specific quality-of-life scores were also significantly better for attacks treated with rizatriptan. At study end, 62% and 17% of patients were very or completely satisfied with rizatriptan and usual non-triptan therapy, respectively. Among those patients who worked for pay, therapy with rizatriptan significantly reduced absenteeism and improved the amount and quality of time at work compared with usual non-triptan therapy. Allowing patients to have experience with rizatriptan may improve the level of medical care for migraine attacks. AD - Healthcare Clinic, Collado Villalba, Madrid, Spain AN - 106727740. Corporate Author: I-MAX Study Group. Language: English. Entry Date: 20040423. Revision Date: 20150711. Publication Type: Journal Article AU - Baos, V. AU - Serrano, A. AU - Torrecilla, M. AU - Bertral, C. AU - Caloto, M. T. AU - Nocea, G. AU - Gerth, W. C. DB - cin20 DP - EBSCOhost IS - 9 KW - Migraine -- Drug Therapy Rizatriptan -- Therapeutic Use Self Report -- Evaluation Treatment Outcomes Absenteeism -- Evaluation Adolescence Adult Aged Analysis of Variance Chi Square Test Descriptive Statistics Diaries Female Fisher's Exact Test Funding Source Male Mann-Whitney U Test McNemar's Test Patient Satisfaction Productivity Quality of Life Questionnaires T-Tests Two-Tailed Test Human N1 - research; tables/charts. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Grant Information: Supported by a grant from Merck Sharpe & Dohme de España, SA. NLM UID: 9712381. PMID: NLM14686564. PY - 2003 SN - 1368-5031 SP - 761-768 ST - Patient-reported benefits of rizatriptan compared with usual non-triptan therapy for migraine in a primary care setting T2 - International Journal of Clinical Practice TI - Patient-reported benefits of rizatriptan compared with usual non-triptan therapy for migraine in a primary care setting UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106727740&site=ehost-live&scope=site VL - 57 ID - 777 ER - TY - JOUR AB - The risk of adjustment problems increases when a child has a serious life-threatening illness. This article estimates the frequency of adjustment problems across multiple domains for children and adolescents with sickle cell anemia (SCA). Parents provided information of the social, emotional, academic, and family adjustment of 327 children with SCA who were being treated at a comprehensive sickle cell clinic serving a predominately poor and urban population. More than 25 percent of these children had emotional adjustment problems in the form of internalizing symptoms such as anxiety and depression. In addition, at least one child in five had problems related to social functioning and academic performance. These impairments were related significantly to the frequency of serious pain episodes but not to absolute family income. No significant differences in the data were found based on family income. The data also showed that the disruptive effects of the illness were related to gender and age. AD - Univ Ctr Child Family, School Social Work, Univ Michigan, 1007 East Huron, Ann Arbor MI 48104-1690 AN - 107447491. Language: English. Entry Date: 19940801. Revision Date: 20200708. Publication Type: Journal Article AU - Barbarin, O. A. AU - Whitten, C. F. AU - Bonds, S. M. DB - cin20 DO - 10.1093/hsw/19.2.112 DP - EBSCOhost IS - 2 KW - Anemia, Sickle Cell -- Psychosocial Factors -- In Infancy and Childhood Anemia, Sickle Cell -- Psychosocial Factors -- In Adolescence Parents -- Psychosocial Factors Social Adjustment Sibling Relations Black Persons Poverty Areas Diagnosis, Psychosocial Pain Interpersonal Relations Child, Preschool Child Adolescence Male Female Human N1 - research; tables/charts. Journal Subset: Allied Health; Peer Reviewed; USA. NLM UID: 7611528. PMID: NLM8045444. PY - 1994 SN - 0360-7283 SP - 112-119 ST - Estimating rates of psychosocial problems in urban and poor children with sickle cell anemia T2 - Health & Social Work TI - Estimating rates of psychosocial problems in urban and poor children with sickle cell anemia UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=107447491&site=ehost-live&scope=site VL - 19 ID - 854 ER - TY - JOUR AB - Parents play an important role in supporting school functioning in youth with chronic pain, but no validated tools exists to assess parental responses to child and adolescent pain behaviors in the school context. Such a tool would be useful in identifying targets of change to reduce pain-related school impairment. The goal of this study was to develop and preliminarily validate the Parent Responses to School Functioning Questionnaire (PRSF), a parent self-report measure of this construct. After initial expert review and pilot testing, the measure was administered to 418 parents of children (ages 6-17 years) seen for initial multidisciplinary chronic pain clinic evaluation. The final 16-item PRSF showed evidence of good internal consistency (α = .82) and 2-week test-retest reliability (intraclass correlation coefficient = .87). Criterion validity was demonstrated by significant correlations with school absence rates and overall school functioning, and construct validity was demonstrated by correlations with general parental responses to pain. Three subscales emerged capturing parents' personal distress, parents' level of distrust of the school, and parents' expectations and behaviors related to their child's management of challenging school situations. These results provide preliminary support for the PRSF as a psychometrically sound tool to assess parents' responses to child pain in the school setting.Perspective: The 16-item PRSF measures parental responses to their child's chronic pain in the school context. The clinically useful measure can inform interventions aimed reducing functional disability in children with chronic pain by enhancing parents' ability to respond adaptively to child pain behaviors. AD - Helen DeVos Children’s Hospital, Departments of Pediatric Psychology and Pediatric Pain and Palliative Medicine and Michigan State University College of Human Medicine, Grand Rapids, Michigan Sheikh Zayed Institute's Pain Medicine Care Complex, Division of Anesthesiology, Pain and Perioperative Medicine at Children's National Health System George Washington University, Washington, DC Department of Anesthesiology, Pain, and Perioperative Medicine, Boston Children's Hospital, Boston, Massachusetts Department of Psychiatry, Harvard Medical School, Boston, Massachusetts AN - 125312414. Language: English. Entry Date: 20180522. Revision Date: 20190211. Publication Type: journal article AU - Barber Garcia, Brittany N. AU - Gray, Laura S. AU - Simons, Laura E. AU - Logan, Deirdre E. DB - cin20 DO - 10.1016/j.jpain.2017.06.011 DP - EBSCOhost IS - 10 KW - Pain -- Diagnosis Schools Parents Adolescence Factor Analysis Child Human Reproducibility of Results Pilot Studies Validation Studies Questionnaires N1 - research. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Pediatric Care. Instrumentation: Parent Responses to School Functioning Questionnaire (PRSF). NLM UID: 100898657. PMID: NLM28729215. PY - 2017 SN - 1526-5900 SP - 1277-1286 ST - Development of the Parent Responses to School Functioning Questionnaire T2 - Journal of Pain TI - Development of the Parent Responses to School Functioning Questionnaire UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=125312414&site=ehost-live&scope=site VL - 18 ID - 344 ER - TY - JOUR AB - Cross, field study that aimed to characterize the population with lumbago treated in the clinic of orthopedics, according to the social, demographic and behavioral variables, and identify the improvement and worsening of pain factors. 29 customers have been interviewed, registered in the orthopedic clinic of a public, academic hospital in Minas Gerais, Brazil. It showed that 58.6% were male, with a mean age of 47. Most were white skinned color (68.9%), was married (55.2%), had overweight and obesity (60.0%) and were ex-smokers (51.7%). The moment when the pain was first felt ranged from one week to 30 years, with an average of 6.8 years. It was found that only 72.4% adopted drug treatment and 31.4%, complementary therapies. As to the factors of improvement, the 'lie down' was cited by 72.4% of respondents and, among the factors of deterioration, 'to remain in the same position for too long' and 'carry weight', reported by 44, 8% of respondents. It is concluded that the factors of improvement and deterioration for lumbago are similar among the subjects studied and the majority only takes medication to control the pain. These findings suggest the need for implementing new programs to promote health so that additional measures may be adopted in the control of pain in this population. AN - 104842792. Language: Portuguese. Entry Date: 20110513. Revision Date: 20150711. Publication Type: Journal Article AU - Barbosa, Maria Helena AU - Silveira, Talita Braga AU - Lemos, Rejane Cussi Assuncao AU - Zuffi, Fernanda Bonato DB - cin20 DP - EBSCOhost IS - 47 KW - Low Back Pain -- Epidemiology -- Brazil Low Back Pain -- Therapy Outcomes (Health Care) Academic Medical Centers Adolescence Adult Aged Alternative Therapies Analgesics -- Therapeutic Use Body Mass Index Brazil Chronic Pain Cross Sectional Studies Data Analysis Software Descriptive Statistics Educational Status Employment Status Epidemiological Research Female Field Studies Hospitals, Public Human Intervertebral Disk Displacement Interviews Low Back Pain -- Drug Therapy Low Back Pain -- Etiology Low Back Pain -- Risk Factors Male Marital Status Middle Age Nutritional Status Obesity Outpatients Pain Measurement Patient Education Smoking N1 - pictorial; research; tables/charts. Journal Subset: Blind Peer Reviewed; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Mexico & Central/South America; Public Health. PY - 2011 SN - 1806-3365 SP - 18-23 ST - Lumbago: factors of improvement and worsening among customers treated in outpatient orthopedics T2 - Saude Coletiva TI - Lumbago: factors of improvement and worsening among customers treated in outpatient orthopedics UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104842792&site=ehost-live&scope=site VL - 8 ID - 599 ER - TY - JOUR AB - Objective: Generalized joint hypermobility (GJH) and fibromyalgia syndrome (FMS) are two clinical conditions that may cause common musculoskeletal pain during childhood. Our study aimed to evaluate the frequency of juvenile FMS and GJH in children aged 11-18 years in the province Trabzon as well as to evaluate the correlation between these two conditions. Material and Methods: This cross-sectional study was conducted in 437 students aged 11-18 years who received education in Trabzon. Questionnaire forms were filled, and each student was examined. The children reported to have any disease were excluded from the study. GJH was diagnosed according to criteria of Beighton diagnosis. The presence of FMS was determined according to the 1990 American College of Rheumatology classification criteria. A total of 437 students [209 girls (52.2%) and 228 (47.8%) boys] participated in the study. The mean age was 14.3±1.7 years for girls and 14.7±1.79 years for boys. Results: The frequency of GJH was found to be 9.1% and that of FMS was found to be 5.9% for children included in the study. Although significant difference was observed among the female and male participants in terms of the frequency of GJH (p=0.023), no such difference was detected in of the frequency of FMS (p=0.065). A statistically significant and highly negative correlation was found between age and Beighton score (r=-0.187, p<0.001). A statistically significant and highly negative correlation was found between body mass index and Beighton score (r=- 0.097, p<0.05). There was a correlation between success level at school and tender points. Both FMS and GJH were detected in one patient. No correlation was detected between Beighton score and tender points. Conclusion: Similar to children in other countries, GJH and FMS are also non-rare clinical conditions in Turkey. AD - Department of Physical Medicine and Rehabilitation, Karadeniz Teknik University Faculty of Medicine, Trabzon, Turkey Department of Pediatric, Karadeniz Teknik University Faculty of Medicine, Trabzon, Turkey Department of Orthopedics and Traumatology, Bezmialem Vakıf University, İstanbul, Turkey AN - 109825648. Language: English. Entry Date: 20150827. Revision Date: 20200708. Publication Type: Journal Article AU - BarÇAk, Ömer Faruk AU - Karkucak, Murat AU - ÇApkin, Erhan AU - KaragÜZel, Gülay AU - DİLber, Beril AU - DedeoĞLu, Süleyman Semih DB - cin20 DO - 10.5152/tftrd.2015.65002 DP - EBSCOhost IS - 1 KW - Fibromyalgia -- Epidemiology -- In Infancy and Childhood Joint Instability -- Epidemiology -- Turkey Turkey Human Cross Sectional Studies Child Adolescence Questionnaires Male Female Descriptive Statistics Goodness of Fit Chi Square Test T-Tests Analysis of Variance Post Hoc Analysis Chi Square Test Pearson's Correlation Coefficient Spearman's Rank Correlation Coefficient N1 - research; tables/charts. Journal Subset: Allied Health; Biomedical; Blind Peer Reviewed; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Middle East; Peer Reviewed. Special Interest: Pediatric Care; Physical Therapy. Instrumentation: Beighton Score. NLM UID: 100961627. PY - 2015 SN - 1302-0234 SP - 6-11 ST - Prevalence of Generalized Joint Hypermobility and Fibromyalgia Syndrome in the Children Population of Trabzon: A Turkish Study T2 - Turkish Journal of Physical Medicine & Rehabilitation / Turkiye Fiziksel Tip ve Rehabilitasyon Dergisi TI - Prevalence of Generalized Joint Hypermobility and Fibromyalgia Syndrome in the Children Population of Trabzon: A Turkish Study UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=109825648&site=ehost-live&scope=site VL - 61 ID - 461 ER - TY - JOUR AB - BACKGROUND: The role of psycho-educational interventions in facilitating adaptation to chronic disease has received growing recognition and is in keeping with policy developments advocating greater involvement of patients in their own care. The purpose of this paper is to provide an overview of the current literature regarding the effectiveness of psycho-educational interventions for children and adolescents with chronic disease, their parents and siblings. METHODS: Electronic searches were conducted using AMED, CINAHL, Cochrane Database, DARE, HTA, MEDLINE, NHS EED, PsycLIT, PsycINFO, and PubMED. Inclusion criteria were systematic reviews, meta-analyses and overviews based on traditional reviews of published literature. The titles of papers were reviewed, abstracts were obtained and reviewed, and full copies of selected papers were obtained. RESULTS: No reviews of psycho-educational interventions were found for either parents or siblings. Twelve reviews of interventions for children and adolescents were identified: chronic disease in general (three); chronic pain (one); asthma (three); chronic fatigue syndrome (CFS)/myalgic encephalomyelitis (ME) (one); diabetes (two); juvenile idiopathic arthritis (JIA) (one) and one informational intervention for paediatric cancer patients. The main focus was on disease management (particularly in asthma and diabetes) with less attention being paid to psychosocial aspects of life with a chronic condition. Overall, there is evidence of effectiveness for interventions incorporating cognitive-behavioural techniques on variables such as self-efficacy, self-management of disease, family functioning, psychosocial well-being, reduced isolation, social competence, knowledge, hope, pain (for chronic headache), lung function (asthma), days absent from school (asthma), visits to A & E (asthma), fatigue (CFS), and metabolic control (diabetes). A number of gaps and limitations were identified across all disease categories, such as inadequate description of interventions, small sample sizes, and lack of evidence regarding cost-effectiveness. CONCLUSION: This overview has highlighted the need to extend the evidence base for psycho-educational interventions, particularly in a UK context. It is essential that effective interventions are implemented and embedded in service provision in order to maximize empowerment through self-care for children, adolescents and their parents. AD - Interdisciplinary Research Centre in Health, School of Health and Social Sciences, Coventry University, Priory Street, Coventry, CV1 5FB, UK; j.barlow@coventry.ac.uk AN - 106602334. Language: English. Entry Date: 20050401. Revision Date: 20200708. Publication Type: Journal Article AU - Barlow, J. H. AU - Ellard, D. R. DB - cin20 DO - 10.1111/j.1365-2214.2004.00474.x DP - EBSCOhost IS - 6 KW - Chronic Disease -- Therapy -- In Infancy and Childhood Psychoeducation -- In Infancy and Childhood Self Care -- In Infancy and Childhood Adolescence Arthritis, Juvenile Rheumatoid -- Therapy Asthma -- Therapy -- In Infancy and Childhood Child Chronic Pain -- Therapy -- In Infancy and Childhood CINAHL Database Cochrane Library Diabetes Mellitus -- Therapy -- In Infancy and Childhood Funding Source Medline Psycinfo Human N1 - research; systematic review. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Grant Information: Department of Health. NLM UID: 7602632. PMID: NLM15527474. PY - 2004 SN - 0305-1862 SP - 637-645 ST - Psycho-educational interventions for children with chronic disease, parents and siblings: an overview of the research evidence base T2 - Child: Care, Health & Development TI - Psycho-educational interventions for children with chronic disease, parents and siblings: an overview of the research evidence base UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106602334&site=ehost-live&scope=site VL - 30 ID - 759 ER - TY - JOUR AB - Headache is a potentially disabling condition involving enduring pain that negatively influences the quality of family life. Behavioural problems are more common in children with headache and are potentially associated with higher levels of parental stress. The aim of this study was to evaluate the extent to which children's behavioural problems were associated with maternal stress and how the child's perception of security in the maternal attachment relationship moderates this association. Seventy-one school-aged children with headache (headache group (HG), age M = 9.8 years old, SD = 1.3) and 71 children from a low-risk normative population (control group (CG), age M = 9.2 years old, SD = 1) and their mothers were involved in the study. Mothers' reports of children's behavioural problems were associated with higher maternal stress in the caring task both in the HG and in the CG. Results also showed that the HG was more at risk for behavioural problems, whereas no difference between groups was detected for parenting stress and for attachment insecurity. In children with headache, perception of attachment security decreased the strength of the association between maternal stress and externalizing behavioural problems. Secure attachment may provide children with headache and their parents with support in managing the negative emotions that arise in the context of significant health issues. Implications for practice are discussed. Copyright © 2015 John Wiley & Sons, Ltd. AD - Department of Brain and Behavioral Sciences, University of Pavia, Pavia Italy Department of Health Sciences, University of Milan, Milan Italy Child Neuropsychiatry Unit, C. Mondino National Neurological Institute, Pavia Italy AN - 120039171. Language: English. Entry Date: 20161216. Revision Date: 20200507. Publication Type: Article AU - Barone, Lavinia AU - Lionetti, Francesca AU - Dellagiulia, Antonio AU - Galli, Federica AU - Molteni, Silvia AU - Balottin, Umberto DB - cin20 DO - 10.1002/icd.1950 DP - EBSCOhost IS - 6 KW - Child Behavior Disorders -- Risk Factors Headache -- Complications -- In Infancy and Childhood Stress, Psychological Mothers Mother-Child Relations Human Attitude Child N1 - research; tables/charts. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 100887625. PY - 2016 SN - 1522-7227 SP - 502-515 ST - Behavioural Problems in Children with Headache and Maternal Stress: Is Children's Attachment Security a Protective Factor? T2 - Infant & Child Development TI - Behavioural Problems in Children with Headache and Maternal Stress: Is Children's Attachment Security a Protective Factor? UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=120039171&site=ehost-live&scope=site VL - 25 ID - 385 ER - TY - JOUR AB - Background: Assessing disparities in health-related quality of Life (HRQoL) is important as a part of health-related disparities in the society. The aim of this study was to explore HRQoL among 12-year-olds in Sweden in terms of differences between years 2005 and 2009 and disparities related to sociodemographic background.Methods: During the school years 2005 and 2009, a total of 18,325 sixth grade students in Sweden were invited to a celiac disease screening study; 13,279 agreed to participate. Jointly with the celiac screening, the children answered a questionnaire that included EuroQol 5 Dimensions-youth (EQ-5D-Y) and their parents responded to separate questionnaires about their own and their child's country of birth, family structure, their employment status, occupation, and education. In total 11,009 child-parent questionnaires were collected. Logistic regression was used to study differences in HRQoL between 2005 and 2009, and between various sociodemographic subgroups.Results: Compared with 2005, children in 2009 reported more pain (OR: 1.20, 95% CI: 1.1-1.3) and more mood problems (OR: 1.35, 95% CI: 1.2-1.5). In general, girls reported more pain and mood problems and had more disparities than boys. There were no significant differences based on parents' occupation, however, children of parents with low or medium education levels reported less "mood problems" than those of parents with high education levels (OR: 0.65, 95% CI: 0.46-0.92) and (OR: 0.84, 95% CI: 0.73-0.96), respectively. A slight variation was seen in HRQoL between children with different migration background. Girls living in small municipalities reported more pain (OR: 1.51, 95% CI: 1.14-2.01), and problems performing usual activities (OR: 3.77, 95% CI: 2.08-6.84), compared to girls living in large municipalities. In addition, children living with two parents had less mood problems than children living in other family constellations.Conclusion: More children reported pain and mood problems in 2009 compared with 2005. To study future trends, health outcomes among children in Sweden should continue to be reported periodically. More efforts should be invested to increase the awareness of health-related disparities as highlighted in this study especially for girls living in small municipalities and children of parents with high education level. AD - Department of Epidemiology and Global Health, Umeå University, Umeå, Sweden Department of Historical, Philosophical and Religious Studies, Umeå University, Umeå, Sweden Department of Pediatrics, Clinical Sciences, Skåne University Hospital, Lund University, Lund, Sweden AN - 134404931. Language: English. Entry Date: In Process. Revision Date: 20190612. Publication Type: journal article. Journal Subset: Biomedical AU - Baroudi, Mazen AU - Petersen, Solveig AU - Namatovu, Fredinah AU - Carlsson, Annelie AU - Ivarsson, Anneli AU - Norström, Fredrik DB - cin20 DO - 10.1186/s12889-019-6429-6 DP - EBSCOhost IS - 1 KW - Quality of Life Health Status Disparities Female Socioeconomic Factors Sweden Male Child Scales N1 - Europe; Public Health; UK & Ireland. Instrumentation: Health-Related Hardiness Scale (HRHS). Grant Information: 521-2004-7093 and 521-2007-2953//The Swedish Research Council/. NLM UID: 100968562. PMID: NLM30704442. PY - 2019 SN - 1471-2458 SP - 1-10 ST - Preteen children's health related quality of life in Sweden: changes over time and disparities between different sociodemographic groups T2 - BMC Public Health TI - Preteen children's health related quality of life in Sweden: changes over time and disparities between different sociodemographic groups UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=134404931&site=ehost-live&scope=site VL - 19 ID - 265 ER - TY - JOUR AB - Objective. Our objective is to describe the use of the PRECEDE model (predisposing, reinforcing, and enabling causes in educational diagnosis and evaluation) to organize needs assessment data in order to define self-management behaviors and plan an educational intervention for children with juvenile rheumatoid arthritis (JRA) and their families. Methods. Analysis was done of needs assessment data collected from several sources 1) literature review, 2) survey of parents of 51 children with JRA, 3) group interview of seven parents of children with JRA, 4) results of pilot programs, and 5) clinical experience of an interdisciplinary pediatric rheumatology team. Results. Two sets of interrelated behavioral factors were identified through the needs assessment: 1) those related to managing the school environment to facilitate optimal participation and to minimize school-related disability, and 2) those related to treating pain and stiffness, intervening in the disease process, and preserving joint function. Conclusion. Both of these sets of behavioral factors may be related to the optimization of children's mobility, joint function, and autonomy of activities of daily living and should be targets of an educational intervention. AD - Department of Health Education, Texas Children's Hospital, and Department of Pediatrics, Baylor College of Medicine AN - 107417014. Language: English. Entry Date: 19950801. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical AU - Bartholomew, L. K. AU - Koenning, G. AU - Dahlquist, L. AU - Barron, K. DB - cin20 DP - EBSCOhost IS - 3 KW - Arthritis, Juvenile Rheumatoid Needs Assessment Health Education Conceptual Framework Program Planning Interviews Surveys Models, Theoretical Convenience Sample Absenteeism Funding Source Quality of Life Learning Environment Psychosocial Aspects of Illness Health Behavior Family Child, Preschool Child Adolescence N1 - Peer Reviewed; USA. Grant Information: This work was supported in part by Project MCJ 485070 from the Maternal and Child Health Bureau, HRSA, DHHS. NLM UID: 8809082. PMID: NLM7727553. PY - 1994 SN - 0893-7524 SP - 136-143 ST - An educational needs assessment of children with juvenile rheumatoid arthritis T2 - Arthritis Care & Research (08937524) TI - An educational needs assessment of children with juvenile rheumatoid arthritis UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=107417014&site=ehost-live&scope=site VL - 7 ID - 853 ER - TY - JOUR AB - Background: The experience of persistent pain in multiple locations is common in youth. Based on current literature, youth with multiple pain sites (MPS) are at risk of experiencing poorer emotional outcomes and a spread of symptoms into late adolescence and adulthood. Little is known regarding the association between MPS with physical and school functioning domains, particularly after initiation of multidisciplinary pain treatment. Therefore, the objective of this study was to examine the association of MPS with disability and school functioning among youth with chronic pain.Methods: A total of 195 patients with chronic pain, aged 8-17, and their parents completed measures assessing patient distress and functioning at a multidisciplinary pain clinic evaluation and at 4-month follow-up.Results: At evaluation, 63% of patients presented with MPS; 25% reporting MPS endorsed pain in five or more locations. When controlling for relevant demographic and emotional distress factors, MPS were associated with lower school functioning at evaluation with a persistent trend at follow-up. Although MPS were not a significant predictor of pain-related disability at evaluation, it emerged as significant at follow-up.Conclusions: Potentially due to the MPS load and the inverse effects that such a pain state has on function, such patients may be at risk for poorer health and school-related outcomes. The mechanisms influencing these relationships appear to extend beyond psychological/emotional factors and warrant further investigation in order to aid in our understanding of youth with MPS.Significance: Youth with MPS may be at risk for experiencing poorer physical and school functioning in comparison with single-site peers, despite treatment initiation. Further research is warranted to inform assessment and treatment approaches for this subgroup of patients. AD - Division of Pain Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children's Hospital, USA Center for Pain and the Brain, Boston Children's and Massachusetts General Hospital, USA Department of Psychiatry, Harvard Medical School, Boston, USA Department of Anesthesiology, Harvard Medical School, Boston, USA Department of Anesthesiology, Perioperative, and Pain Medicine, Stanford University Medical School, Palo Alto, USA AN - 130105003. Language: English. Entry Date: 20181215. Revision Date: 20190809. Publication Type: journal article AU - Basch, M. C. AU - Chow, E. T. AU - Logan, D. E. AU - Borsook, D. AU - Schechter, N. L. AU - Simons, L. E. DB - cin20 DO - 10.1002/ejp.1201 DP - EBSCOhost IS - 6 KW - Emotions Stress, Psychological -- Psychosocial Factors Chronic Pain -- Psychosocial Factors Parents -- Psychosocial Factors Child Male Human Female Adolescence Pain Measurement Child, Disabled -- Psychosocial Factors Validation Studies Comparative Studies Evaluation Research Multicenter Studies N1 - research. Journal Subset: Biomedical; Blind Peer Reviewed; Continental Europe; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. Grant Information: K23 HD067202/HD/NICHD NIH HHS/United States. NLM UID: 9801774. PMID: NLM29436161. PY - 2018 SN - 1090-3801 SP - 1134-1141 ST - Cumulative effects of multiple pain sites in youth with chronic pain T2 - European Journal of Pain TI - Cumulative effects of multiple pain sites in youth with chronic pain UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=130105003&site=ehost-live&scope=site VL - 22 ID - 298 ER - TY - JOUR AD - University of Cincinnati, Cincinnati, Ohio AN - 127983516. Language: English. Entry Date: 20191116. Revision Date: 20180215. Publication Type: Article. Supplement Title: Mar2018 Supplement. Journal Subset: Biomedical AU - Beckmann, E. AU - Gibler, R. AU - Kashikar-Zuck, S. AU - Lynch-Jordan, A. AU - Mano, K. Jastrowski DB - cin20 DO - 10.1016/j.jpain.2017.12.119 DP - EBSCOhost N1 - Peer Reviewed; USA. NLM UID: 100898657. PY - 2018 SN - 1526-5900 SP - S51-S51 ST - (205) - Heightened school anxiety among adolescents with chronic pain T2 - Journal of Pain TI - (205) - Heightened school anxiety among adolescents with chronic pain UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=127983516&site=ehost-live&scope=site VL - 19 ID - 312 ER - TY - JOUR AB - Background: Thirty percent of children with acute otitis media (AOM) experience symptoms < 7 days after initiating treatment, highlighting the importance of comprehensive discharge instructions. Methods: We randomized caregivers of children 6 months to 17 years presenting to the emergency department (ED) with AOM to discharge instructions using a video on management of pain and fever to a paper handout. The primary outcome was the AOM Severity of Symptom (AOM‐SOS) score at 72 hours postdischarge. Secondary outcomes included caregiver knowledge (10‐item survey), absenteeism, recidivism, and satisfaction (5‐item Likert scale). Results: A total of 219 caregivers were randomized and 149 completed the 72‐hour follow‐up (72 paper and 77 video). The median (IQR) AOM‐SOS score for the video was significantly lower than paper, even after adjusting for preintervention AOM‐SOS score and medication at home (8 [7–11] vs. 10 [7–13], respectively; p = 0.004). There were no significant differences between video and paper in mean (±SD) knowledge score (9.2 [±1.3] vs. 8.8 [±1.8], respectively; p = 0.07), mean (±SD) number of children that returned to a health care provider (8/77 vs. 10/72, respectively; p = 0.49), mean (±SD) number of daycare/school days missed by child (1.2 [±1.5] vs. 1.1 [±2.1], respectively; p = 0.62), mean (±SD) number of workdays missed by caregiver (0.5 [±1] vs. 0.8 [±2], respectively; p = 0.05), or median (IQR) satisfaction score (5 [4–5] vs. 5 [4–5], respectively; p = 0.3). Conclusions: Video discharge instructions in the ED are associated with less perceived AOM symptomatology compared to a paper handout. AD - From the, Department of Pediatrics, Division of Paediatric Emergency Medicine, Schulich School of Medicine & Dentistry, Western University, London Ontario the, Department of Pediatrics, Division of Paediatric Emergency Medicine, University of Alberta, Edmonton Alberta Women and Children's Health Research Institute, Edmonton Alberta the, Children's Health Research Institute, London Health Sciences Centre, London Ontario and the, Department of Family Medicine, Cumming School of Medicine, University of Calgary, Calgary Alberta, Canada AN - 140232307. Language: English. Entry Date: 20191211. Revision Date: 20201130. Publication Type: Article AU - Belisle, Sheena AU - Dobrin, Andrei AU - Elsie, Sharlene AU - Ali, Samina AU - Brahmbhatt, Shaily AU - Kumar, Kriti AU - Jasani, Hardika AU - Miller, Michael AU - Ferlisi, Frank AU - Poonai, Naveen AU - Macy, Michelle L. DB - cin20 DO - 10.1111/acem.13839 DP - EBSCOhost IS - 12 KW - Emergency Service Teaching Materials Audiovisuals Parents -- Education Caregivers -- Education Otitis Media with Effusion -- Education Otitis Media with Effusion -- Therapy -- In Infancy and Childhood Otitis Media with Effusion -- Therapy -- In Adolescence Human Randomized Controlled Trials Education, Continuing (Credit) Infant Child, Preschool Child Adolescence Pain Management Scales Severity of Illness Indices Otitis Media with Effusion -- Diagnosis Health Knowledge -- Evaluation Absenteeism -- Evaluation Recidivism -- Evaluation Personal Satisfaction -- Evaluation Caregiver Attitudes Health Personnel Acute Disease Child Day Care Congresses and Conferences N1 - CEU; proceedings; research; tables/charts; randomized controlled trial. Note: For CE see www.wileyhealthlearning.com/aem. Journal Subset: Biomedical; Peer Reviewed; USA. Instrumentation: 5-item Likert scale; AOM Severity of Symptom (AOM-SOS) score. NLM UID: 9418450. PY - 2019 SN - 1069-6563 SP - 1326-1335 ST - Video Discharge Instructions for Acute Otitis Media in Children: A Randomized Controlled Open‐label Trial...Pediatric Academic Societies Annual Meeting, Toronto, Ontario, May 2018 T2 - Academic Emergency Medicine TI - Video Discharge Instructions for Acute Otitis Media in Children: A Randomized Controlled Open‐label Trial...Pediatric Academic Societies Annual Meeting, Toronto, Ontario, May 2018 UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=140232307&site=ehost-live&scope=site VL - 26 ID - 205 ER - TY - JOUR AB - To investigate the associations of various types of employment with six self reported health indicators, taking into account the part played by demographic variables, individual working conditions and four ecological indicators at the country level. Cross sectional survey (structured interview) of a sample of the active population of 15 European countries aged 15 years or over. Main independent variables were nine types of employment categorised as follows: small employers, full and part time permanent employees, full and part time fixed term employees, full and part time sole traders and full and part time temporary contracts. Main outcome measures were three self reported health related outcomes (job satisfaction, health related absenteeism, and stress) and three self reported health problems (overall fatigue, backache, and muscular pains). Logistic regression and multilevel models were used in the analyses. 15 countries of the European Union. 15 146 employed persons aged 15 or over. Precarious employment was consistently and positively associated with job dissatisfaction but negatively associated with absenteeism and stress (as compared with full time permanent workers). Fatigue, backache and muscular pains also tended to be positively associated with precarious employment, particularly with full time precarious employment. Small employers reported high percentages of stress and fatigue, but absenteeism was relatively low. Sole traders generally reported high percentages of all outcomes, except for absenteeism, which was low. For each type of employment (except temporary contracts), full time workers tended to report worse health outcomes than part time workers. Patterns were generally consistent across countries. Associations persisted after adjustment for individual level working conditions and were not modified by country level variables. This study is the first to examine the relations between various types of employment and six health related indicators for all 15 member states of the European Union. Suggestive patterns worthy of further exploration have been found. Standardised definitions of types of underemployment and health related outcomes, more potent epidemiological designs and the inclusion of socioeconomic information (for example, social security systems, incapacity benefit schemes) at the regional level are proposed for inclusion in further research. AD - Occupational Health Research Unit, Department of Experimental Sciences and Health, Universitat Pompeu Fabra, Barcelona, Spain. fernando.benavides@cexs.upf.es AN - 104721242. Language: English. Entry Date: 20110610. Revision Date: 20150711. Publication Type: Journal Article AU - Benavides, F. G. AU - Benach, J. AU - Diez-Roux, A. V. AU - Roman, C. DB - cin20 DO - 10.1136/jech.54.7.494 DP - EBSCOhost KW - Employment -- Psychosocial Factors Health Status Indicators Job Satisfaction Adolescence Adult Back Pain -- Epidemiology Back Pain -- Etiology Cross Sectional Studies Employment -- Classification Employment -- Trends Europe Fatigue -- Epidemiology Fatigue -- Etiology Female Human Logistic Regression Male Middle Age Muscular Diseases -- Epidemiology Muscular Diseases -- Etiology Odds Ratio Sick Leave -- Statistics and Numerical Data Stress, Psychological -- Epidemiology Stress, Psychological -- Etiology N1 - research. Journal Subset: Biomedical; Blind Peer Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; Public Health; UK & Ireland. NLM UID: 7909766. PMID: NLM10846191. PY - 2000 SN - 0143-005X SP - 494-501 ST - How do types of employment relate to health indicators? Findings from the second European survey on working conditions T2 - Journal of Epidemiology & Community Health TI - How do types of employment relate to health indicators? Findings from the second European survey on working conditions UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104721242&site=ehost-live&scope=site ID - 820 ER - TY - JOUR AB - Objective.-The aim of this study was to find the prevalence of migraine and headache in schoolchildren in the United Arab Emirates and to determine the genetic and environmental factors associated with these conditions. Methods.-A cross-sectional population study was performed from October 1995 to June 1996. Subjects were selected by a multistage stratified sampling procedure. Data were collected by screening questionnaires followed by clinical interviews. Twelve primary schools and 1400 schoolchildren of United Arab Emirates nationality resident in the Al Ain City, Dubai, and Sharjah emirates were recruited for this study. A total of 1159 (82.7%) schoolchildren gave their consent to the study. Results.-The estimated prevalence rates for headache and migraine were 36.9% and 13.7%, respectively. The prevalence of headache is increased with age, the highest prevalence being in 13-year-old children (17.5%). Of the 159 children who fulfilled the diagnostic criteria for migraine, 76 were boys whose mean age (± SD) was 10.3 years ± 2.8 years, and 83 were girls (mean age 9.9 ± 2.5 years). Of the children who had migraine, 20 (12.6%) had migraine without aura, and 13 (8.2%) had migraine with aura. The most common migraine symptoms in schoolchildren had been aggravated by physical activity (47.2%) and a positive family history of migraine (46.5%). The most common illnesses were infectious illnesses (41.5%). There was a strong relationship between migraine and the timing of examinations (46.5%). The most common environmental exposure for migraine was found to be playing on a computer (45.9%), followed by loud noise (41.5%), and a hot climate (37.1%). In familial occurrence of headache among immediate relatives, the most frequently affected relative was the mother (17.6%). Conclusion.-Headache and migraine are common in childhood and may be influenced by social, familial, environmental, and psychological factors. AN - 106095147. Language: English. Entry Date: 20081219. Revision Date: 20200708. Publication Type: Journal Article AU - Bener, A. AU - Uduman, S. AU - Qassimi, E. AU - Khalaily, G. AU - Sztriha, L. AU - Kilpelainen, H. AU - Obineche, E. DB - cin20 DO - 10.1046/j.1526-4610.2000.00021.x DP - EBSCOhost IS - 2 KW - Environment Migraine -- Etiology Migraine Students -- Statistics and Numerical Data Adolescence Child Cross Sectional Studies Demography Female Headache -- Epidemiology Headache -- Etiology Male Migraine -- Epidemiology Prevalence United Arab Emirates Human N1 - research. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 2985091R. PMID: NLM10759915. PY - 2000 SN - 0017-8748 SP - 152-157 ST - Genetic and environmental factors associated with migraine in schoolchildren T2 - Headache: The Journal of Head & Face Pain TI - Genetic and environmental factors associated with migraine in schoolchildren UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106095147&site=ehost-live&scope=site VL - 40 ID - 824 ER - TY - JOUR AB - Background: Patients with autism spectrum disorder and developmental delay or encephalopathy rarely demonstrate no or negligible hair and nail growth, suggesting a biotin-responsive clinical disorder.Methods: A ten-year-old girl presented with features of autism spectrum disorder, isolated headaches, and episodes of headaches and limb shaking. Her medical history revealed that her hair and nails did not grow. Administration of biotin restored her nail and hair growth and improved intellectual ability and school performance. Her episodes of headaches, single limb shaking, and loss of consciousness responded to administration of acetazolamide, and her school performance and social skills further improved.Results: A de novo c.1091 C > T, p.T364M pathogenic variant was found in the ATP1A2 gene by whole-exome sequencing, but a genetic etiology in the biotin-responsive metabolic pathways was not identified.Conclusions: The combination of biotin and acetazolamide treatment was successful in restoring normal mental function and school performance. Poor or no clinical nail and hair growth in any child with a developmental delay-autism spectrum disorder presentation should be considered as evidence for a biotin-responsive genetic disorder even when exome testing is negative. AD - Genetics Division, Joe DiMaggio Children's Hospital, and Charles E. Schmidt College of Medicine, Hollywood, Florida Neurology Division, Nicklaus Children's Hospital, Miami, Florida GeneDx, Gaithersburg, Maryland AN - 127589636. Language: English. Entry Date: 20190426. Revision Date: 20191029. Publication Type: journal article AU - Benke, Paul J. AU - Duchowny, Michael AU - McKnight, Dianalee DB - cin20 DO - 10.1016/j.pediatrneurol.2017.10.013 DP - EBSCOhost KW - Anticonvulsants -- Therapeutic Use Vitamin B Complex -- Therapeutic Use Acetazolamide -- Therapeutic Use Biotin -- Therapeutic Use Nail Diseases -- Diagnosis Nail Diseases -- Drug Therapy Adenosine Triphosphatase Nail Diseases Hair Diseases Hair Diseases -- Drug Therapy Migraine -- Drug Therapy Human Child Female Hair Diseases -- Diagnosis Migraine -- Diagnosis Migraine Validation Studies Comparative Studies Evaluation Research Multicenter Studies N1 - research. Journal Subset: Biomedical; USA. NLM UID: 8508183. PMID: NLM29413639. PY - 2018 SN - 0887-8994 SP - 61-64 ST - Biotin and Acetazolamide for Treatment of an Unusual Child With Autism Plus Lack of Nail and Hair Growth T2 - Pediatric Neurology TI - Biotin and Acetazolamide for Treatment of an Unusual Child With Autism Plus Lack of Nail and Hair Growth UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=127589636&site=ehost-live&scope=site VL - 79 ID - 321 ER - TY - JOUR AB - Headache is a highly prevalent condition and is the leading cause for school absences. Despite the rich literature supporting behavioral treatments for headache, many child psychologists mistakenly perceive that they lack appropriate training to treat children with headache. Likewise, many physicians feel underprepared to refer the child for behavioral treatments. This article serves as a primer, providing tools for the general child psychologist or mental health provider by answering frequently asked questions. First, we provide a concise background on pathophysiology and medical care for headache. We then detail aspects of behavioral interventions for headache, including a case example. We included a limited list of up-to-date references most relevant to the child psychologist who does not treat headache on a regular basis to support further reading. By reviewing this primer, local mental health professionals can provide children with headache access to high-quality, evidence-based clinical care closer to home. AD - Cleveland Clinic, Cleveland, OH, USA Kent State University, OH, USA AN - 120237905. Language: English. Entry Date: 20161221. Revision Date: 20161228. Publication Type: Article AU - Benore, Ethan AU - Monnin, Kara DB - cin20 DO - 10.1177/0009922816638665 DP - EBSCOhost IS - 1 KW - Headache -- Therapy -- In Infancy and Childhood Behavior Therapy Psychologists Headache -- Physiopathology Comorbidity Headache -- Diagnosis Headache -- Etiology Adolescence Female Child N1 - case study; forms. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Peer Reviewed; USA. NLM UID: 0372606. PY - 2017 SN - 0009-9228 SP - 71-76 ST - Behavioral Treatment for Headaches in Children: A Practical Guide for the Child Psychologist T2 - Clinical Pediatrics TI - Behavioral Treatment for Headaches in Children: A Practical Guide for the Child Psychologist UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=120237905&site=ehost-live&scope=site VL - 56 ID - 378 ER - TY - JOUR AB - Background: Many children suffering from chronic headache and migraine present with comorbid functional disability, including physical, social, emotional, and academic activities. For children severely impaired by headache, intensive interdisciplinary pain rehabilitation treatment (IIPT) can improve functioning. However, there are limited data evaluating children's response to rehabilitation across several time points. Objective: This study aims to evaluate the trajectory of recovery for children undergoing IIPT for chronic headache, as well as to examine the proposed assumption that physical and psychosocial functioning improves prior to a reported reduction in pain. Methods: A retrospective analysis of patient‐reported outcomes in a clinical database of 135 children admitted to an IIPT program between the years 2008 and 2014 was analyzed. Available data across 5 separate time points (up to 1‐year post‐discharge) were reviewed. Results: One hundred and thirty‐five children of mean age 15.2 (SD = 2.2) and 74% female provided data for review. Linear mixed model demonstrated a statistically significant improvement in pain‐specific measures of functioning, including daily functioning (change estimate = −14.53) emotional functioning (change estimate = −14.63), family functioning (change estimate = −5.78), and school absences (change estimate = −11.47) over a 12‐month period (all P's ≤ .01). A more general measure of quality of life improved during the program, based upon child (change estimate = +10.07) and parent report (change estimate = +15.31); although these gains did not continue to improve post‐discharge. As expected, although children did not report a reduction in pain during rehabilitation (change estimate = +0.07), they did report a significant drop in perceived pain in the 12 months following discharge from the program (change estimate = −2.12, P ≤ .01). Conclusions: Children with chronic headache and migraine who are severely functionally impaired demonstrated linear improvement in pain‐specific patient‐reported outcomes over time; however, there remains a need for improved methodology in analyzing response to IIPT programs. AD - Cleveland Clinic ‐ Pediatric Behavioral Health, Cleveland OH, USA Cleveland Clinic Children's Hospital ‐ Quantitative Health Sciences, Cleveland OH, USA AN - 133235684. Language: English. Entry Date: 20181130. Revision Date: 20191101. Publication Type: Article AU - Benore, Ethan AU - Webster, Erin E. AU - Wang, Lu AU - Banez, Gerard DB - cin20 DO - 10.1111/head.13389 DP - EBSCOhost IS - 10 KW - Patient-Reported Outcomes Pediatric Care Migraine -- Rehabilitation -- In Adolescence Headache -- Rehabilitation -- In Adolescence Program Evaluation Recovery Functional Assessment Human Prospective Studies Retrospective Design Patient Discharge Adolescence Female Male Data Analysis, Statistical Emotions Family Functioning Pain Management Severity of Disability N1 - research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 2985091R. PY - 2018 SN - 0017-8748 SP - 1556-1567 ST - Longitudinal Analysis of Patient‐Reported Outcomes From an Interdisciplinary Pediatric Pain Rehabilitation Program for Children With Chronic Migraine and Headache T2 - Headache: The Journal of Head & Face Pain TI - Longitudinal Analysis of Patient‐Reported Outcomes From an Interdisciplinary Pediatric Pain Rehabilitation Program for Children With Chronic Migraine and Headache UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=133235684&site=ehost-live&scope=site VL - 58 ID - 279 ER - TY - JOUR AB - This study investigated the late effects of childhood cancer on participation and quality of life. Ninety-two percent of survivors (9 to 18 years of age) reported living with late effects of lower extremity pain and numbness, memory and attention deficits, and fatigue, depression, or both. Semistructured interviews with 25 survivors using the Canadian Occupational Performance Measure and the Adolescent Activity Card Sort captured frequencies, interests, and barriers for a range of activities. Survivors reported diminished engagement in vigorous leisure activities, chores, and community activities. Lower engagement in social activities was correlated with lower quality of life scores, as measured by the Pediatric Cancer Quality of Life Inventory-32. Despite these findings of significant cognitive and physical problems, none of the 25 survivors had individualized education programs in school, nor were any receiving occupational therapy at the time the survey was completed. The findings emphasize the importance of advocacy for occupational therapy services for survivors of childhood cancer and examination of adolescent survivor participation in, and goals for, typical activities. AD - Instructor, Program in Occupational Therapy, Washington University School of Medicine, St. Louis, MO; cberg@wustl.edu AN - 105432659. Language: English. Entry Date: 20090925. Revision Date: 20200708. Publication Type: Journal Article AU - Berg, C. AU - Neufeld, P. AU - Harvey, J. AU - Downes, A. AU - Hayashi, R. J. DA - Summer2009 DB - cin20 DO - 10.3928/15394492-20090611-04 DP - EBSCOhost IS - 3 KW - Cancer Survivors Childhood Neoplasms Quality of Life Activities of Daily Living Adolescence Adolescent Development Child Childhood Neoplasms -- Therapy Clinical Assessment Tools Cognition Disorders Convenience Sample Depression Fatigue Female Goal-Setting Headache Interpersonal Relations Male Occupational Therapy Pain Physical Activity Human N1 - research; tables/charts. Journal Subset: Allied Health; Peer Reviewed; USA. Instrumentation: Canadian Occupational Performance Measure (COPM); Short Blessed Cognitive Screening Tool; Pediatric Cancer Quality of Life Inventory-32 (PCQL-32) (Varni et al). NLM UID: 101144015. PY - 2009 SN - 1539-4492 SP - 116-124 ST - Late effects of childhood cancer, participation, and quality of life of adolescents T2 - OTJR: Occupation, Participation & Health TI - Late effects of childhood cancer, participation, and quality of life of adolescents UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105432659&site=ehost-live&scope=site VL - 29 ID - 657 ER - TY - JOUR AB - Objective: This population-based study on school-aged girls aimed to estimate the rate of peri-menstrual headache, evaluate headache pain pattern during the menstrual cycle, and verify its relationships with physical, psychosocial and life-style factors.Methods: The students (n = 4973) fulfilled a self-administered questionnaire on demographic and behavioral characteristics, menarche, menstrual pattern and features including headache and dysmenorrhea. The prevalence of headache and the mean pain intensity score at the three menstrual cycle phases (premenstrual, menstrual, in-between period) were estimated, both overall and by gynecological year. Furthermore, the prevalence of three different patterns of headache (peri menstrual/mid-cycle/acyclic) was evaluated, together with the mean pain intensity score.Results: The overall prevalence of headache at least once at any time during the menstrual cycle was 64.4%. At multivariable logistic analysis, gynecological age (OR 1.07; 95%CI 1.03-1.12), middle social level (1.24; 1.01-1.55, compared to high social level), physical activity (0.67; 0.51-0.89), oral contraceptive use (1.34; 1.04-1.73) and dysmenorrhea (2.30; 1.54-3.42) were significantly associated with headache. Among girls with headache, 83.4% had peri-menstrual headache (44.6% premenstrual, 38.8% menstrual), 3.5% mid-cycle headache and 13.2% acyclic headache. The gynaecological age and dysmenorrhea were significantly associated with the headache pattern (p = 0.03 and p < 0.0001, respectively).Conclusions: This study suggests that peri-menstrual headache is highly prevalent among adolescents. In girls, the headache rate linearly raises with higher gynecological age; menses-related painful syndromes, such as headache and dysmenorrhea, are strongly interrelated. The anamnesis and monitoring of menstrual health should be mandatory when taking care of girls with headache. AD - Child Psychiatric Unit, Local Health and Social Care Services - ULSS 6 Euganea, Padua, Italy Internal Medicine and Therapeutics, Section of Childhood and Adolescence, Foundation IRCCS San Matteo, University of Pavia, Pavia, Italy Department of Woman's and Child Health, University of Padua, Padua, Italy Department of Pediatrics, University of Parma, Parma, Italy Division of Pediatrics, Department of Mother and Child Health, Azienda Ospedaliero-Universitaria Maggiore della Carità, Novara, Italy Department of Pediatrics, "Carlo Poma" Hospital, Mantova, Italy Department of Pediatric Endocrinology, Ospedale Infantile Regina Margherita, Turin, Italy Private Accredited Hospital Quisisana, Pediatric and Adolescent Outpatients Clinic, Ferrara, Italy University of Trieste, Trieste, Italy Department of Pediatrics, Regional Hospital of Bolzano, Bolzano, Italy Unit of Biostatistics, Epidemiology Public Health, Department of Cardiac, Thoracic, Vascular Science and Public Health, University of Padua, Padua, Italy AN - 134673238. Language: English. Entry Date: 20191128. Revision Date: 20200102. Publication Type: journal article. Supplement Title: Jan2019 Supplement 1. Journal Subset: Asia AU - Bianchin, Luigi AU - Bozzola, Mauro AU - Battistella Pier, Antonio AU - Bernasconi, Sergio AU - Bona, Gianni AU - Buzi, Fabio AU - De Sanctis, Carlo AU - De Sanctis, Vincenzo AU - Tonini, Giorgio AU - Radetti, Giorgio AU - Rigon, Franco AU - Perissinotto, Egle DB - cin20 DO - 10.1007/s12098-018-2829-3 DP - EBSCOhost IS - 1 KW - Headache -- Etiology Menstrual Cycle -- Psychosocial Factors Headache -- Epidemiology Menstrual Cycle -- Physiology Menstruation Female Prevalence Life Style Chi Square Test Dysmenorrhea -- Etiology Adolescence Young Adult Age of Onset Menarche Logistic Regression Adult Schools Students -- Statistics and Numerical Data Exercise Multivariate Analysis Psychosocial Adjustment to Illness Scale Social Readjustment Rating Scale N1 - Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed. Instrumentation: Psychosocial Adjustment to Illness Scale (PAIS); Longitudinal Interval Follow-Up Evaluation (LIFE); Social Readjustment Rating Scale (SRRS) (Holmes and Rahe). NLM UID: 0417442. PMID: NLM30637681. PY - 2019 SN - 0019-5456 SP - 25-33 ST - Menstrual Cycle and Headache in Teenagers T2 - Indian Journal of Pediatrics TI - Menstrual Cycle and Headache in Teenagers UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=134673238&site=ehost-live&scope=site VL - 86 ID - 268 ER - TY - JOUR AB - Objective.-To determine the prevalence of migraine and episodic tension-type headache (ETTH) among university students as well as its impact on academic performance and quality of life. Background.-Headache is a very common symptom in clinical practice. The reduced capacities due to migraine can be profound, and more studies are needed to evaluate, in particular, school performance. Few studies have been conducted to evaluate the impact of tension-type headache on work productivity, quality of life, and the impact of headache on school performance. Methods.-A total of 1022 students were interviewed. Two questionnaires were utilized, a standard one that permitted a diagnosis of migraine or ETTH according to the criteria of the International Headache Society and a second one consisting of a battery of tests on quality of life. Results.-A total of 256 students (25%) had migraine and 336 (32.9%) reported ETTH. When in pain, migraineurs demonstrated a 62.7% decrease in productivity while studying, compared with a 24.4% decrease in those with ETTH. Fifty percent of migraineurs tried to study despite the pain, compared with 53.2% of those with ETTH. With respect to all other items tested, there was a significantly higher impairment in the presence of migraine than in the presence of ETTH and in the presence of the latter compared with a control situation. Conclusions.-The present study confirms the profound impact of headache on the performance of university students, with this impact much more evident among migraineurs but also important among students with ETTH. AN - 106094091. Language: English. Entry Date: 20081219. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical AU - Bigal, M. E. AU - Bigal, J. M. AU - Betti, M. AU - Bordini, C. A. AU - Speciali, J. G. DB - cin20 DP - EBSCOhost IS - 7 KW - Migraine -- Physiopathology Migraine -- Psychosocial Factors Quality of Life Students Success Tension Headache -- Physiopathology Tension Headache -- Psychosocial Factors Adult Female Male N1 - Peer Reviewed; USA. NLM UID: 2985091R. PMID: NLM11554960. PY - 2001 SN - 0017-8748 SP - 710-719 ST - Evaluation of the Impact of Migraine and Episodic Tension-type Headache on the Quality of Life and Performance of a University Student Population T2 - Headache: The Journal of Head & Face Pain TI - Evaluation of the Impact of Migraine and Episodic Tension-type Headache on the Quality of Life and Performance of a University Student Population UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106094091&site=ehost-live&scope=site VL - 41 ID - 812 ER - TY - JOUR AD - Head of Fundraising and Communications, The Migraine Trust AN - 104449590. Language: English. Entry Date: 20120601. Revision Date: 20150711. Publication Type: Journal Article AU - Bloomfield, Tony DB - cin20 DP - EBSCOhost IS - 10 KW - Academic Performance Health Services Needs and Demand Migraine Students Absenteeism Confidence Consumer Advocacy England Health Information Migraine -- Drug Therapy Pamphlets Prevalence -- England School Accommodation Support, Psychosocial N1 - pictorial. Journal Subset: Europe; Nursing; Peer Reviewed; UK & Ireland. NLM UID: 101297722. PY - 2009 SN - 1752-2803 SP - 475-476 ST - Understanding the needs of migraineurs in schools T2 - British Journal of School Nursing TI - Understanding the needs of migraineurs in schools UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104449590&site=ehost-live&scope=site VL - 4 ID - 641 ER - TY - JOUR AB - Most athletes who experience a sports-related concussion recover from the acute effects within a few weeks. However, some children and adolescents with concussion experience symptoms for many weeks, or even months after the injury. Subacute and chronic symptoms related to concussion are particularly concerning in children, because cognitive deficits, headache or neck pain, sleep dysfunction, and emotional dysregulation can affect school performance and social function at a critical period of development and maturation. This article reviews the epidemiology of subacute symptoms after pediatric concussion and the current recommendations for the assessment and management of these symptoms in children and adolescents. AD - Division of Pediatric Neurology, Seattle Children's Hospital, B-5552 Sand Point Way Northeast, Seattle, WA 98105, USA. AN - 108200431. Language: English. Entry Date: 20120413. Revision Date: 20150712. Publication Type: Journal Article. Journal Subset: Allied Health AU - Blume, H. K. AU - Lucas, S. AU - Bell, K. R. DB - cin20 DP - EBSCOhost IS - 4 KW - Athletic Injuries -- Complications Postconcussion Syndrome -- Epidemiology Postconcussion Syndrome -- Therapy Adolescence Child Cognition Disorders -- Diagnosis Cognition Disorders -- Etiology Cognition Disorders -- Therapy Headache -- Diagnosis Headache -- Etiology Headache -- Therapy Affective Disorders -- Diagnosis Affective Disorders -- Etiology Affective Disorders -- Therapy Postconcussion Syndrome -- Diagnosis Postconcussion Syndrome -- Etiology Balance, Postural Sex Factors Sleep Disorders -- Diagnosis Sleep Disorders -- Etiology Sleep Disorders -- Therapy N1 - Peer Reviewed; USA. Special Interest: Physical Therapy. NLM UID: 9102787. PMID: NLM22050942. PY - 2011 SN - 1047-9651 SP - 665-681 ST - Subacute concussion-related symptoms in youth T2 - Physical Medicine & Rehabilitation Clinics of North America TI - Subacute concussion-related symptoms in youth UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=108200431&site=ehost-live&scope=site VL - 22 ID - 572 ER - TY - JOUR AB - Context: Medical educators are seeking improved measures to assess the clinical competency of residents as they complete their graduate medical education.Objective: To assess residents' perceptions of their preparedness to provide common clinical services during their last year of graduate medical education.Design, Setting, and Participants: A 1998 national survey of residents completing their training in 8 specialties (internal medicine, pediatrics, family practice, obstetrics/gynecology, general surgery, orthopedic surgery, psychiatry, and anesthesiology) at academic health centers in the United States. A total of 2626 residents responded (response rate, 65%).Main Outcome Measures: Residents' reports of their preparedness to perform clinical and nonclinical tasks relevant to their specialties.Results: Residents in all specialties rated themselves as prepared to manage most of the common conditions they would encounter in their clinical career. However, more than 10% of residents in each specialty reported that they felt unprepared to undertake 1 or more tasks relevant to their disciplines, such as caring for patients with human immunodeficiency virus/acquired immunodeficiency syndrome or substance abuse (family practice) or nursing home patients (internal medicine); performance of spinal surgery (orthopedic surgery) or abdominal aortic aneurysm repair (general surgery); and management of chronic pain (anesthesiology).Conclusions: Overall, residents in their last year of training at academic health centers rate their clinical preparedness as high. However, opportunities for improvement exist in preparing residents for clinical practice. AD - Institute for Health Policy, Massachusetts General Hospital, 50 Staniford St, 9th Floor, Suite 901, Boston, MA 02114, USA Institute for Health Policy, Massachusetts General Hospital, 50 Staniford St, 9th Floor, Suite 901, Boston, MA 02114; dblumenthal@partners.org AN - 106981720. Language: English. Entry Date: 20021129. Revision Date: 20200701. Publication Type: journal article AU - Blumenthal, D. AU - Gokhale, M. AU - Campbell, E. G. AU - Weissman, J. S. AU - Blumenthal, D. AU - Gokhale, M. AU - Campbell, E. G. AU - Weissman, J. S. DB - cin20 DO - 10.1001/jama.286.9.1027 DP - EBSCOhost IS - 9 KW - Interns and Residents Clinical Competence Physician Attitudes Education, Continuing (Credit) Academic Medical Centers United States Surveys Self Assessment Specialties, Medical Stratified Random Sample Descriptive Statistics Internship and Residency Education, Medical Students, Medical Funding Source Human N1 - CEU; research; tables/charts. Commentary: Merrill D, Rathmell J P, Lema M J. Graduating residents' perceptions of their preparedness for practice. (JAMA) 12/5/2001; 286 (21): 2666-2667. Journal Subset: Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Grant Information: Supported by a grant from the Commonwealth Fund Task Force on Academic Health Centers of New York. NLM UID: 7501160. PMID: NLM11559286. PY - 2001 SN - 0098-7484 SP - 1027-1110 ST - Preparedness for clinical practice: reports of graduating residents at academic health centers T2 - JAMA: Journal of the American Medical Association TI - Preparedness for clinical practice: reports of graduating residents at academic health centers UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106981720&site=ehost-live&scope=site VL - 286 ID - 807 ER - TY - JOUR AB - Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder defined by impairing levels of inattention, disorganization, and/or hyperactivity-impulsivity. ADHD often persists into adulthood, with resultant impairments of social, academic and occupational functioning. ADHD is a very common disease during childhood and, the pooled overall prevalence of ADHD was found to be 5.29%. When screening for ADHD, clinicians should try to develop rapport with patients and their caregivers to increase the likelihood that they will follow the diagnostic process and treatment. The current drugs that have received Food and Drug Administration-approval for ADHD include stimulants (methylphenidate and dextroamphetamine) and non-stimulants (atomoxetine, guanfacine, and clonidine). Stimulants improve inattention, hyperactivity, and impulsivity in addition to decreasing disruptive behaviors and promoting academic achievement and the maintenance of appropriate friendships. In order to enhance drug compliance, the use of long-acting stimulants is increasing. Atomoxetine is a selective norepinephrine reuptake blocker, the effects of which may take 2 to 6 weeks to be noticeable. Furthermore, α2 agonists may help to improve behavioral side effects, tics, and sleep problems during stimulant or atomoxetine use. Common side effects of stimulants and atomoxetine include headache, stomachache, and loss of appetite. Routine electorcardiography before medication is not recommended unless there is a specific indication. Methylphenidate and atomoxetine are safe as first line therapies, and their side effects are well tolerated. AD - Department of Psychiatry, Inje University Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea AN - 134304253. Language: Korean. Entry Date: 20190130. Revision Date: 20191121. Publication Type: Article AU - Bongseog, Kim DB - cin20 DO - 10.5124/jkma.2019.62.1.49 DP - EBSCOhost IS - 1 KW - Attention Deficit Hyperactivity Disorder -- Drug Therapy Attention Deficit Hyperactivity Disorder -- Diagnosis Caregivers United States Food and Drug Administration Methylphenidate -- Therapeutic Use Dextroamphetamine -- Therapeutic Use Atomoxetine -- Therapeutic Use Antihypertensive Agents -- Therapeutic Use Clonidine -- Therapeutic Use Impulsive Behavior Disruptive Behavior Academic Achievement Friendship Medication Compliance Norepinephrine -- Therapeutic Use Adverse Drug Event Headache Appetite Drug Tolerance N1 - tables/charts. Journal Subset: Asia; Biomedical; Peer Reviewed. NLM UID: 100957048. PY - 2019 SN - 1975-8456 SP - 49-55 ST - Pharmacotherapy for attention-deficit/ hyperactivity disorder T2 - Journal of the Korean Medical Association / Taehan Uisa Hyophoe Chi TI - Pharmacotherapy for attention-deficit/ hyperactivity disorder UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=134304253&site=ehost-live&scope=site VL - 62 ID - 272 ER - TY - JOUR AB - The purpose of the paper is to analyse the associations between learning health promotion from the health dialogue and socio-demographic and psycho-social variables. The theoretial framework is based on empowerment and health promotion and on experiential learning theory. The study is the Danish contribution to the WHO-collaborative study Health Behaviour in Schoolchildren. In 1991, a nationwide random sample of pupils 11, 13, 15-year-olds (n=1860) answered a standardised questionnaire about perceived health, health behaviour social situation as well as the health dialogue with the school health nurse. Pupils from lower social classes reported a high proportion of learning health promotion. Among the study population, 31% had learned health promotion, mostly the 11-year-old pupils, and more girls than boys. Learning health promotion was associated with school satisfaction, unhappiness, nervousness, tiredness, physical exercise, puberty-related issues, headache and backache. Weekly recurring needs predicted the highest proportion of learning health promotion. Headache was the main reason for spontaneous contact. The second reason was problems with social relations. Pupils who were inclined to spontaneous visits had a positive attitude to school. Age, school satisfaction and headaches may be essential predictors of learning health promotion. Three steps in a learning spiral were applied: concrete experience (CE), reflective observation (RO), abstract conceptualization (AC). AN - 107172244. Language: English. Entry Date: 19990301. Revision Date: 20150820. Publication Type: Journal Article AU - Borup, I. K. DB - cin20 DP - EBSCOhost IS - 3 KW - School Health Education Health Promotion -- In Adolescence Empowerment -- In Adolescence Attitude to Health -- Evaluation -- In Adolescence Students, High School -- Psychosocial Factors Students, Elementary -- Psychosocial Factors Conceptual Framework Random Sample Questionnaires Socioeconomic Factors Denmark Experiential Learning Learning Theory School Health Nursing Kolb's Experiential Learning Theory Bivariate Statistics Chi Square Test Data Analysis Software Multivariate Analysis of Variance Statistical Significance Child Adolescence Male Female Human N1 - research; tables/charts. Journal Subset: Blind Peer Reviewed; Continental Europe; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Nursing; Peer Reviewed. NLM UID: 8700224. PY - 1998 SN - 0107-4083 SP - 26-31 ST - Adolescents learning health promotion: pupils' evaluation of contacts with the school health nurse T2 - Nordic Journal of Nursing Research & Clinical Studies / Vård i Norden TI - Adolescents learning health promotion: pupils' evaluation of contacts with the school health nurse UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=107172244&site=ehost-live&scope=site VL - 18 ID - 833 ER - TY - JOUR AB - Objective: To examine if students who re-visit the school nurse use medicines differently than other students when exposed to aches and psychological problems.Methods: The study includes all 11-, 13- and 15-year-old students from a random sample of schools in Denmark, response rate 87 per cent, n = 5,205. The data collection followed the internationally standardized HBSC questionnaire. This study includes an item about students’ re-visits to the school nurse, items about frequency of four complaints (headache, stomach-ache, difficulties in getting to sleep, and nervousness) and medicine use in the past month for these four complaints.Results: In total, 8.6 per cent of the students had re-visited the school nurse. There was a strong and graded association between frequency of complaints and medicine use for the relevant complaint. Students who re-visited the school nurse had higher odds for medicine use than other students. The association between frequency of complaints and medicine use was stronger among students who had not re-visited the school nurse as compared to the students who had re-visited the school nurse. One example is the OR (95 per cent CI) for medicine use for headache among students who experienced headache monthly vs. seldom/never and at least weekly vs. seldom/never. Among students who did not re-visit the school nurse, the OR estimates were 5.32 (4.61–6.14) and 13.6 (10.5–17.6) and among students who did, OR estimates were 3.65 (2.32–5.75) and 7.07 (3.58–14.0).Conclusion: The school nurse may reduce the students’ proneness to use medicine when they experience complaints. AD - Nordic School of Public Health, Gothenburg, Sweden ina.borup@nhv.se National Institute of Public Health at the University of Southern Denmark, Copenhagen, Denmark National Institute of Public Health at the University of Southern Denmark, Copenhagen, Denmark, Institute of Public Health, University of Copenhagen, Denmark AN - 65219842. Language: English. Entry Date: 20111006. Revision Date: 20111129. Publication Type: Article AU - Borup, Ina K. AU - Andersen, Anette AU - Holstein, Bjørn E. DB - cin20 DO - 10.1177/0017896910375884 DP - EBSCOhost IS - 3 KW - School Health Nursing Health Behavior -- In Adolescence Health Resource Utilization -- In Adolescence Drugs, Non-Prescription -- In Adolescence Human Funding Source Child Adolescence Random Sample Denmark Questionnaires Odds Ratio Confidence Intervals Headache -- Drug Therapy Abdominal Pain -- Drug Therapy Insomnia -- Drug Therapy Anxiety -- Drug Therapy Health Promotion Nursing Role Focus Groups Students, Elementary Students, Middle School Male Female Chi Square Test Descriptive Statistics Cross Sectional Studies N1 - research; tables/charts. Journal Subset: Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Health Promotion/Education; Peer Reviewed; UK & Ireland. Special Interest: Pediatric Care. Grant Information: Health Insurance Foundation and the Nordea Foundation. NLM UID: 0374646. PY - 2011 SN - 0017-8969 SP - 274-284 ST - Re-visit to the school nurse and adolescents’ medicine use T2 - Health Education Journal TI - Re-visit to the school nurse and adolescents’ medicine use UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=65219842&site=ehost-live&scope=site VL - 70 ID - 575 ER - TY - JOUR AB - Objective.- Clinical trials concerning cervical spine manipulation and mobilization in children and adolescents with cervicogenic headache are lacking. Methods.- We performed a multicenter, prospective, randomized, placebo-controlled, and blinded trial in 52 children and adolescents (21 boys, 31 girls) aged 7-15. After prospective baseline documentation for 2 months patients were either assigned to placebo or true manipulation with another 2-month follow-up. Main outcome measures were defined as: percentage of days with headache, total duration of headache, days with school absence due to headache, consume of analgesics, intensity of headache. Results.- We did not find a significant difference comparing the groups with placebo and true manipulation with respect to the defined main outcome measures. Conclusions.- We were not able to show an efficacy of cervical spine manipulation in 52 children and adolescents. AD - Zentrum für Kinder- und Jugendmedizin, Helios Klinikum Wuppertal, Heusnerstr. 40, D-42283 Wuppertal, Germany AN - 105302343. Language: English. Entry Date: 20100326. Revision Date: 20200708. Publication Type: Journal Article AU - Borusiak, P. AU - Biedermann, H. AU - Boßerhoff, S. AU - Opp, J. DB - cin20 DO - 10.1111/j.1526-4610.2009.01550.x DP - EBSCOhost IS - 2 KW - Headache -- Therapy -- In Infancy and Childhood Manual Therapy -- Evaluation -- In Infancy and Childhood Adolescence Chi Square Test Child Clinical Trials Descriptive Statistics Female Funding Source Human Male P-Value Paired T-Tests Prospective Studies Scales Visual Analog Scaling N1 - clinical trial; research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. Grant Information: Wagner-Stiftung (Wagener Foundation). NLM UID: 2985091R. PMID: NLM19845788. PY - 2010 SN - 0017-8748 SP - 224-230 ST - Lack of efficacy of manual therapy in children and adolescents with suspected cervicogenic headache: results of a prospective, randomized, placebo-controlled, and blinded trial T2 - Headache: The Journal of Head & Face Pain TI - Lack of efficacy of manual therapy in children and adolescents with suspected cervicogenic headache: results of a prospective, randomized, placebo-controlled, and blinded trial UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105302343&site=ehost-live&scope=site VL - 50 ID - 635 ER - TY - JOUR AB - Subjective health complaints are common among adolescents. There is evidence that girls are more likely to register complaints than boys. This study examines gender differences in the relationship between daily smoking and recurrent subjective health complaints in school-aged adolescents in the USA. A cross-sectional design with a multistage probability sample was used to survey 13 339 middle and high school students (grades 6 through 10) with the US 2001-2002 Health Behavior in School-Aged Children Survey. Recurrent subjective health complaints were higher for adolescents who smoke daily and experiment with cigarettes than for those who never smoke. In logistic regression analyses, the odds of daily smoking increased twofold for both boys and girls who report recurrent irritability/bad temper. For girls, the odds of daily smoking were higher among those who reported recurrent headache, stomachache and backache compared with never smokers. For boys only recurrent backache and feeling dizzy were associated with increased odds of daily smoking. The relationship between recurrent subjective health complaints and daily smoking provides new insights into both conditions for school-aged adolescents. Findings from this study suggest different patterns of association between daily smoking and recurrent subjective health complaints occur for girls and boys. Further studies are needed to explore causes and treatment of daily smoking and recurrent health complaints among school-aged children. AD - The EMMES Corporation NICHD (Eunice Kennedy Shriver National Institute of Child Health and Human Development), Rockville, and Department of General Pediatrics and Adolescent Medicine, Johns Hopkins University, Baltimore, MD, USA AN - 104801053. Language: English. Entry Date: 20110705. Revision Date: 20200708. Publication Type: Journal Article AU - Botello-Harbaum, M. AU - Haynie, D. L. AU - Murray, K. W. AU - Iannotti, R. J. DB - cin20 DO - 10.1111/j.1365-2214.2010.01147.x DP - EBSCOhost IS - 4 KW - Smoking Health Behavior Human United States Adolescence Students Cross Sectional Studies Surveys Self Report Questionnaires Checklists Chi Square Test Logistic Regression N1 - research; tables/charts. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Pediatric Care. NLM UID: 7602632. PMID: NLM20825423. PY - 2011 SN - 0305-1862 SP - 551-558 ST - Cigarette smoking status and recurrent subjective health complaints among US school-aged adolescents T2 - Child: Care, Health & Development TI - Cigarette smoking status and recurrent subjective health complaints among US school-aged adolescents UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104801053&site=ehost-live&scope=site VL - 37 ID - 579 ER - TY - JOUR AB - Objective: To describe the prevalence of depression in children with chronic fatigue syndrome (CFS)/myalgic encephalomyelitis (ME) and investigate the relationship between depression in CFS/ME and clinical symptoms such as fatigue, disability, pain and school attendance.Design: Cross-sectional survey data using the Hospital Anxiety and Depression Scale (HADS) collected at assessment.Setting: Specialist paediatric CFS/ME service in the South West.Patients: Children aged 12-18 years with CFS/ME.Main Outcome Measure: Depression was defined as scoring >9 on the HADS depression scale.Results: 542 subjects had complete data for the HADS and 29% (156/542) (95% CI 25% to 33%) had depression. In a univariable analysis, female sex, poorer school attendance, and higher levels of fatigue, disability, pain, and anxiety were associated with higher odds of depression. Age of child and duration of illness were not associated with depression. In a multivariable analysis, the factors most strongly associated with depression were disability, with higher scores on the physical function subscale of the 36 item Short Form (SF-36).Conclusions: Depression is commonly comorbid with CFS/ME, much more common than in the general population, and is associated with markers of disease severity. It is important to screen for, identify and treat depression in this population. AD - Centre for Child and Adolescent Health, School for Social and Community Medicine, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK; esther.crawley@bristol.ac.uk. AN - 104284007. Language: English. Entry Date: 20130719. Revision Date: 20200708. Publication Type: journal article AU - Bould, Helen AU - Collin, Simon M. AU - Lewis, Glyn AU - Rimes, Katharine AU - Crawley, Esther DB - cin20 DO - 10.1136/archdischild-2012-303396 DP - EBSCOhost IS - 6 KW - Depression -- Etiology Fatigue Syndrome, Chronic -- Complications Severity of Illness Indices Adolescence Child Cross Sectional Studies Depression -- Epidemiology Depression -- Psychosocial Factors Fatigue Syndrome, Chronic -- Epidemiology Fatigue Syndrome, Chronic -- Psychosocial Factors Fatigue -- Etiology Fatigue -- Psychosocial Factors Female Human Male Pain -- Etiology Pain -- Psychosocial Factors Prevalence Psychological Tests Questionnaires Scales Schools Students -- Psychosocial Factors N1 - research. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Pediatric Care. Instrumentation: Hospital Anxiety and Depression Scale (HADS). Grant Information: CS/08/08/06//Department of Health/United Kingdom. NLM UID: 0372434. PMID: NLM23619200. PY - 2013 SN - 0003-9888 SP - 425-428 ST - Depression in paediatric chronic fatigue syndrome T2 - Archives of Disease in Childhood TI - Depression in paediatric chronic fatigue syndrome UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104284007&site=ehost-live&scope=site VL - 98 ID - 520 ER - TY - JOUR AB - Background: This study describes how painful events affect the health-related quality of life (HRQL) of children with sickle cell disease (SCD) and determines the responsiveness of a generic HRQL measure in SCD. Our hypotheses were twofold: (1) HRQL is significantly impaired at presentation to the emergency department for a painful event and (2) PedsQL 4.0 Acute Version Generic Core Scales is responsive to change in the evolution of a painful event.Procedure: This prospective cohort study included 57 children with SCD. HRQL was measured with the Acute Version of the PedsQL 4.0 Generic Core Scales, completed by child (self-report) and caregiver (proxy report) at presentation and 7 days post-discharge. Independent comparisons of HRQL scores were made between children in the study cohort and a published reference sample of children with SCD in baseline health (historical SCD controls).Results: Median PedsQL scores at presentation were significantly lower than historical SCD controls in all domains for child self-report and all domains except social and school functioning in parent-proxy. Clinically and statistically significant changes in HRQL between presentation and post-discharge resulted in similar HRQL scores at 7 days post-discharge to historical SCD controls.Conclusions: The PedsQL is responsive to change; thus a useful tool to measure the impact of interventions in future SCD clinical trials. Painful events significantly diminish all domains of HRQL and this improves 7 days post-discharge. AD - Department of Pediatric Hematology/Oncology, Medical College of Wisconsin, The Children's Research Institute of the Children's Hospital of Wisconsin, Milwaukee, WI 53226, USA Department of Pediatric Hematology/Oncology, Medical College of Wisconsin, The Children's Research Institute of the Children's Hospital of Wisconsin, Milwaukee, WI 53226, USA. abrandow@mcw.edu AN - 105276895. Language: English. Entry Date: 20100129. Revision Date: 20200708. Publication Type: journal article AU - Brandow, A. M. AU - Brousseau, D. C. AU - Pajewski, N. M. AU - Panepinto, J. A. AU - Brandow, Amanda M. AU - Brousseau, David C. AU - Pajewski, Nicholas M. AU - Panepinto, Julie A. DB - cin20 DO - 10.1002/pbc.22222 DP - EBSCOhost IS - 1 KW - Anemia, Sickle Cell -- Complications Anemia, Sickle Cell -- Psychosocial Factors Health Status Pain -- Etiology Quality of Life Vascular Diseases -- Etiology Adolescence Adult Child Child, Preschool Female Human Male Pain Measurement Prospective Studies Scales Young Adult N1 - research. Journal Subset: Biomedical; Peer Reviewed; USA. Instrumentation: Acute Version of the PedsQL 4.0 Generic Core Scales. Grant Information: K23 HL080092/HL/NHLBI NIH HHS/United States. NLM UID: 101186624. PMID: NLM19653296. PY - 2010 SN - 1545-5009 SP - 92-97 ST - Vaso-occlusive painful events in sickle cell disease: impact on child well-being T2 - Pediatric Blood & Cancer TI - Vaso-occlusive painful events in sickle cell disease: impact on child well-being UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105276895&site=ehost-live&scope=site VL - 54 ID - 640 ER - TY - JOUR AB - Background: Sickle cell disease (SCD) pain is acute or chronic, leads to school absenteeism, impaired health-related quality of life and early mortality. Given that little is known about children with SCD and chronic pain, we (1) described characteristics of these children and (2) evaluated the impact of a multidisciplinary pain management model on health care utilization.Procedure: A retrospective cohort study of children with SCD evaluated and treated in our institution's multidisciplinary pain clinic between 1999 and 2008 was conducted. Referrals occur when children require chronic opioids and/or have frequent pain hospitalizations. Descriptive statistics evaluated patient characteristics and Wilcoxon-Signed Rank evaluated change in median number of pain hospitalizations 1 year before and after referral.Results: Median age of 19 children identified was 15 years (IQR 11-17); significantly more were female (78.9% vs. 21.1%; P = 0.012). At time of referral, all patients reported taking opioids, 68.4% were taking hydroxyurea, half of those not on hydroxyurea started it (n = 3), none were chronically transfused and one initiated transfusions upon referral. Majority (89.5%) learned non-pharmacologic pain management techniques. Median number of pain hospitalizations between the year before and after referral significantly decreased [5(IQR 3-6) to 1(IQR 0-4); P = 0.006]. To further delineate the pain clinic's effect, analysis was repeated after removing children initiating hydroxyurea/transfusions upon referral. The significant decrease in hospitalizations persisted [5(IQR 3-6) to 1(IQR 0-4; P = 0.022].Conclusions: A multidisciplinary pain management model appears to have decreased SCD pain hospitalizations. Results of this retrospective study will need to be tested in a prospective randomized trial. AD - Section of Pediatric Hematology/Oncology, Milwaukee, Wisconsin, USA Section of Pediatric Hematology/Oncology, Milwaukee, Wisconsin; Medical College of Wisconsin/Children's Research Institute of the Children's Hospital of Wisconsin, Milwaukee, Wisconsin. abrandow@mcw.edu. AN - 104570477. Language: English. Entry Date: 20120323. Revision Date: 20200708. Publication Type: journal article AU - Brandow, A. M. AU - Weisman, S. J. AU - Panepinto, J. A. AU - Brandow, Amanda M. AU - Weisman, Steven J. AU - Panepinto, Julie A. DB - cin20 DO - 10.1002/pbc.22874 DP - EBSCOhost IS - 5 KW - Anemia, Sickle Cell -- Complications Pain -- Etiology Adolescence Anemia, Sickle Cell -- Psychosocial Factors Child Child, Preschool Prospective Studies Female Hospitalization Male Pain -- Psychosocial Factors Pain Clinics Pain Measurement Prognosis Quality of Life Retrospective Design Funding Source Human Scales N1 - research. Journal Subset: Biomedical; Peer Reviewed; USA. Instrumentation: Health-Related Quality of Life (HRQOL). Grant Information: K23 HL80092/HL/NHLBI NIH HHS/United States. NLM UID: 101186624. PMID: NLM21370412. PY - 2011 SN - 1545-5009 SP - 789-793 ST - The impact of a multidisciplinary pain management model on sickle cell disease pain hospitalizations T2 - Pediatric Blood & Cancer TI - The impact of a multidisciplinary pain management model on sickle cell disease pain hospitalizations UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104570477&site=ehost-live&scope=site VL - 56 ID - 585 ER - TY - JOUR AB - For children with chronic abdominal pain, the early introduction of stress as a potential cause is likely to improve outcome. Parents underestimate their child's awareness of and capacity to worry about everyday events. Parents, children, and teachers need to be convinced that functional symptoms are a normal feature of life. The need for empathy and quality discussion between doctor, parents, and child concerning potential causes of stress is critical. All reinforcement should be removed including insistence on continued school attendance. Cognitive behavioural therapy appears to be helpful in resistant cases. Medication such as antidepressants should be avoided unless prescribed by a child psychiatrist. AD - The University of Notre Dame Australia, Fremantle, Australia. AN - 108132480. Language: English. Entry Date: 20121019. Revision Date: 20150712. Publication Type: Journal Article. Journal Subset: Biomedical AU - Brett, T. AU - Rowland, M. AU - Drumm, B. DB - cin20 DP - EBSCOhost IS - 600 KW - Abdominal Pain -- Etiology Abdominal Pain -- Therapy Adolescence Child Family Practice Patient History Taking -- Methods Parent-Child Relations Parents -- Education Physical Examination -- Methods Referral and Consultation N1 - Europe; Peer Reviewed; UK & Ireland. NLM UID: 9005323. PMID: NLM22781991. PY - 2012 SN - 0960-1643 SP - 386-387 ST - An approach to functional abdominal pain in children and adolescents T2 - British Journal of General Practice TI - An approach to functional abdominal pain in children and adolescents UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=108132480&site=ehost-live&scope=site VL - 62 ID - 550 ER - TY - JOUR AB - OBJECTIVE: To examine possible risk and protective factors for school absenteeism among adolescents referred to a hospital-based behavioral treatment program. DESIGN: Data obtained from intake interviews, screening questionnaires, and baseline headache diaries of 283 consecutive adolescents referred for behavioral treatment of recurrent headache were reviewed for demographics, length of headache history, headache type, current headache activity, symptoms of anxiety and depression, perceived self-efficacy regarding headache control, school performance, participation in extracurricular activities, and school absenteeism. The study population was divided into 2 groups at the median number of days missed due to headache in the previous 6 months that school was in session. Adolescents who missed 2 or less days of school due to headache (low absenteeism) were compared with those who missed more than 2 days (high absenteeism). RESULTS: Compared with the low absenteeism group, the high absenteeism group had higher scores on the Children's Depression Inventory (8.7 +/- 6.5 versus 6.8 +/- 6.2, P <.05) and lower academic performance (2.1 +/- 1.0 versus 1.7 +/- 0.8, P <.0001). The 2 groups were not statistically different in age, sex, length of headache history, type of headache, current headache frequency or intensity scores, anxiety scores, self-efficacy ratings, or participation in extracurricular activities. CONCLUSIONS: In a referred population, students who missed more school due to headache had higher depression scores and lower academic performance than students who missed less school. A directional relationship, however, cannot be implied from these results. Future studies should investigate the complex relationship between recurrent adolescent headache, potential risk or protective factors, and school absenteeism. AD - University of Washington, Children's Hospital and Regional Medical Center, 4800 Sand Point Way NE, Seattle, WA 98105 AN - 106783093. Language: English. Entry Date: 20081219. Revision Date: 20200708. Publication Type: Journal Article AU - Breuner, C. C. AU - Smith, M. S. AU - Womack, W. M. DB - cin20 DO - 10.1111/j.1526-4610.2004.04050.x DP - EBSCOhost IS - 3 KW - Absenteeism -- In Adolescence Headache -- Epidemiology -- In Adolescence School Health Adolescence Chi Square Test Descriptive Statistics Female Interviews Male P-Value Psychological Tests Questionnaires Record Review Research Instruments Retrospective Design State-Trait Anxiety Inventory T-Tests Human N1 - research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. Instrumentation: Children's Depression Inventory (CDI) (Kovacs and Beck); State-Trait Anxiety Inventory (STAI) (Spielberger). NLM UID: 2985091R. PMID: NLM15012658. PY - 2004 SN - 0017-8748 SP - 217-222 ST - Factors related to school absenteeism in adolescents with recurrent headache T2 - Headache: The Journal of Head & Face Pain TI - Factors related to school absenteeism in adolescents with recurrent headache UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106783093&site=ehost-live&scope=site VL - 44 ID - 772 ER - TY - JOUR AB - Background: An increasing number of children with complex health needs are being educated in mainstream classes. CFS/ME is a complex and disabling condition, and there is little guidance on how primary school teachers can support younger children with this condition. To improve care, it is important to understand what these children need in the school setting, and the barriers and facilitators to teachers providing this support. The aims for this qualitative study were to explore teachers' views about CFS/ME, their experiences of supporting a pupil with CFS/ME and their perspectives on the barriers and facilitators to providing support.Methods: We recruited families from an NHS specialist paediatric CFS/ME service and families were eligible if the child was aged between 5 and 11 years and had a diagnosis of CFS/ME. We gained written consent/assent from families to invite the child's teacher to participate in a qualitative interview. We contacted these teachers, gained written consent and then carried out semi-structured qualitative interviews. Interviews were audio-recorded, transcribed, anonymised and analysed thematically. Interviews took place between July 2018 and December 2018.Results: We interviewed 11 teachers; their pupil's age ranged from 5 to 11 years and school attendance ranged from 0 to 80%. Theme 1: Most teachers provided rich descriptions of their pupil's CFS/ME; they consistently described cognitive dysfunction and significant fatigue, but beyond this the symptoms varied from one account to the next (from mobility problems, to aches and pains, digestive problems, headaches, nausea and hypersensitivity). These teachers noted the ripple effects on their pupil's social, emotional and academic functioning. Two of the eleven teachers said that they did not observe symptoms of CFS/ME, expressing a degree of scepticism about the diagnosis. Theme 2: Teachers described a close relationship with their pupil. They said they understood the individual needs of the child and portrayed positive and proactive attitudes towards providing support. The type of support provided included facilitating rest breaks and limiting strenuous activities; using practical strategies to address cognitive, physical, social and emotional difficulties; maintaining a connection with the child during their absences from school; and encouraging the child to talk about their health and wellbeing. Teachers noted that receiving formal confirmation of the child's diagnosis enabled them to put this support in place. Theme 3: The adaptations they described were often intuitive, rather than being based on a knowledge of CFS/ME. Teachers wanted more resources to increase their understanding of the condition and its management.Conclusions: Primary school teachers want to provide effective support for children with CFS/ME. Clinical services should consider working in collaboration with teachers to equip them with evidence-based strategies for CFS/ME management in the primary school setting. AD - Population Health Sciences, Bristol Medical School, University of Bristol, 1-5 Whiteladies Road, BS8 1NU, Bristol, UK AN - 147906959. Language: English. Entry Date: In Process. Revision Date: 20210214. Publication Type: journal article. Journal Subset: Biomedical AU - Brigden, Amberly AU - Shaw, Alison AU - Crawley, Esther DB - cin20 DO - 10.1186/s12887-020-02461-7 DP - EBSCOhost IS - 1 N1 - Europe; Peer Reviewed; UK & Ireland. Grant Information: DRF-2017-10-169/DH_/Department of Health/United Kingdom. NLM UID: 100967804. PMID: NLM33397331. PY - 2021 SN - 1471-2431 SP - 1-9 ST - "it's a medical condition … you need to support as much as possible": a qualitative analysis of teachers' experiences of chronic fatigue syndrome / myalgic encephalomyelitis (CFS/ME) T2 - BMC Pediatrics TI - "it's a medical condition … you need to support as much as possible": a qualitative analysis of teachers' experiences of chronic fatigue syndrome / myalgic encephalomyelitis (CFS/ME) UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=147906959&site=ehost-live&scope=site VL - 21 ID - 151 ER - TY - JOUR AB - This is a report of the successful use of hypnotic suggestions aimed at encouraging self-assertion and self-acceptance in 51 children aged from 6-15 seen in a general medical practice with psychogenic enuresis or abdominal pain, school phobias, behavioural problems or chronic anxiety. All children treated were passive, timid and unassertive. The psychodynamics of passivity and of assertive therapy are discussed. Thirty-nine children were rated at a two-year follow-up as completely recovered; twelve made no permanent improvement. The average total time spent on treatment was only one and a half hours so this approach to hypnotherapy may be of interest to general medical practitioners as well as child psychiatrists and therapists. AN - 107302645. Language: English. Entry Date: 19981201. Revision Date: 20150711. Publication Type: Journal Article AU - Browne, S. E. DB - cin20 DP - EBSCOhost IS - 1 KW - Hypnosis -- In Infancy and Childhood Psychotherapy -- In Infancy and Childhood Pediatric Care Prospective Studies Interviews Self Concept -- In Infancy and Childhood Child Adolescence Male Female Human N1 - research; tables/charts. Journal Subset: Alternative/Complementary Therapies; Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 9108980. PY - 1997 SN - 0960-5290 SP - 59-62 ST - Brief hypnotherapy with passive children T2 - Contemporary Hypnosis (John Wiley & Sons, Inc.) TI - Brief hypnotherapy with passive children UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=107302645&site=ehost-live&scope=site VL - 14 ID - 843 ER - TY - JOUR AB - Objective: This study examined key functional outcomes following a 3-week interdisciplinary pediatric pain rehabilitation program for adolescents with chronic pain. Maintenance of gains was evaluated at 3-month follow-up.Methods: Participants included 171 adolescents (12 to 18 y of age) with chronic pain who completed a hospital-based outpatient pediatric pain rehabilitation program. Participants completed measures of functional disability, depressive symptoms, pain catastrophizing, opioid use, school attendance, and pain severity at admission, discharge, and at 3-month follow-up.Results: Similar to other interdisciplinary pediatric pain rehabilitation program outcome studies, significant improvements were observed at the end of the program. These improvements appeared to be maintained or further improved at 3-month follow-up. Nearly 14% of the patients were taking daily opioid medication at admission to the program. All adolescents were completely tapered off of these medications at the end of the 3-week program and remained abstinent at 3-month follow-up.Discussion: This study adds to the available data supporting interdisciplinary pediatric pain rehabilitation as effective in improving functioning and psychological distress even when discontinuing opioids. Implications for future research and limitations of the study are discussed. AD - Department of Psychiatry & Psychology, Mayo Clinic Pediatric Pain Rehabilitation Center. Department of Psychiatry & Psychology, Mayo Clinic, Jacksonville, FL. Department of Anesthesiology, Mayo Clinic, Rochester, MN. Department of Nursing, Mayo Clinic, Rochester, MN. Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN. AN - 122879602. Language: English. Entry Date: 20180720. Revision Date: 20190212. Publication Type: journal article AU - Bruce, Barbara K. AU - Ale, Chelsea M. AU - Harrison, Tracy E. AU - Bee, Susan AU - Luedtke, Connie AU - Geske, Jennifer AU - Weiss, Karen E. DB - cin20 DO - 10.1097/AJP.0000000000000433 DP - EBSCOhost IS - 6 KW - Chronic Pain -- Rehabilitation Pain -- Therapy Schools Chronic Pain -- Psychosocial Factors Ambulatory Care Pain Measurement Prospective Studies Disability Evaluation Child Male Treatment Outcomes Adolescence Analgesics, Opioid -- Therapeutic Use Depression -- Rehabilitation Female Human N1 - research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 8507389. PMID: NLM27584815. PY - 2017 SN - 0749-8047 SP - 535-542 ST - Getting Back to Living: Further Evidence for the Efficacy of an Interdisciplinary Pediatric Pain Treatment Program T2 - Clinical Journal of Pain TI - Getting Back to Living: Further Evidence for the Efficacy of an Interdisciplinary Pediatric Pain Treatment Program UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=122879602&site=ehost-live&scope=site VL - 33 ID - 361 ER - TY - JOUR AB - This study examines an 11-year-old boy with a known history of a large previously asymptomatic arachnoid cyst (AC) presenting with acute onset of right facial droop, hemiplegia, and expressive aphasia. Shortly after arrival to the emergency department, the patient exhibited complete resolution of right-sided hemiplegia but developed headache and had persistent word-finding difficulties. Prior to symptom onset while in class at school, there was an absence of reported jerking movements, headache, photophobia, fever, or trauma. At the time of neurology consultation, the physical exam showed mildly delayed cognitive processing but was otherwise unremarkable. The patient underwent MRI scanning of the brain, which revealed left convexity subdural hematohygroma and perirolandic cortex edema resulting from ruptured left frontoparietal AC. He was evaluated by neurosurgery and managed expectantly. He recovered uneventfully and was discharged two days after presentation remaining asymptomatic on subsequent outpatient visits. The family express concerns regarding increased anxiety and mild memory loss since hospitalization. AD - Department of Neurology and Pediatrics, University of Louisville SOM, Louisville, KY 40202, USA Department of Neurology and Pediatrics, Vanderbilt University, Nashville, TN 37420, USA Department of Neurology and Pediatrics, University of Louisville, Louisville, KY 40202, USA Department of Neurological Surgery and Pediatrics, University of Louisville, Louisville, KY 40202, USA AU - Bryden, Anne AU - Majors, Natalie AU - Puri, Vinay AU - Moriarty, Thomas DB - cin20 DO - 10.3390/children8020078 DP - EBSCOhost IS - 2 N1 - Accession Number: 149094699. Language: English. Entry Date: In Process. Revision Date: 20210313. Publication Type: Article. PY - 2021 SN - 2227-9067 SP - 1-5 ST - A Rare Case of Spontaneous Arachnoid Cyst Rupture Presenting as Right Hemiplegia and Expressive Aphasia in a Pediatric Patient T2 - Children TI - A Rare Case of Spontaneous Arachnoid Cyst Rupture Presenting as Right Hemiplegia and Expressive Aphasia in a Pediatric Patient UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=149094699&site=ehost-live&scope=site VL - 8 ID - 146 ER - TY - JOUR AB - Tourette's syndrome (TS) is a neuropsychiatric disorder of childhood onset characterized by multiple motor and phonic tics that fluctuate over time. Tic symptoms often improve by late adolescence, but some children and adults with TS may experience significant tic-related morbidity, including social and family problems, academic difficulties, and pain. When more conservative interventions are not successful, and when certain psychiatric co-morbidities further complicate the clinical profile, treating TS with an atypical antipsychotic medication may be a reasonable second-tier approach. However, the evidence supporting efficacy and safety of the atypical antipsychotics for treatment of tics is still very limited. The objective of this paper is to provide an updated overview of the role of atypical antipsychotics for treatment of TS, with evidence-based guidance on their use. Evidence for efficacy of different typical and atypical antipsychotics for treatment of tics was examined by conducting a systematic, keyword-related search of 'atypical antipsychotics' and 'Tourette's syndrome' in PubMed (National Library of Medicine, Washington, DC, USA). Four recent treatment consensus publications were also reviewed. This review focused on literature published from 2000 to 2013 and on available randomized controlled trials in TS. Evidence supporting the use of atypical antipsychotics for treatment of TS is limited. There are few randomized medication treatment trials in TS (i.e. risperidone, aripiprazole, ziprasidone), which employed varying methodologies, thereby restricting meaningful comparisons among studies. Future collaborations among clinical sites with TS expertise employing high-quality study design may better elucidate the role of atypical antipsychotics for treatment of TS. AD - Department of Psychiatry, North Shore-LIJ Health System, Hofstra University School of Medicine, 400 Community Drive Manhasset 11030 USA AN - 103978242. Language: English. Entry Date: 20140723. Revision Date: 20200708. Publication Type: Journal Article AU - Budman, Cathy DB - cin20 DO - 10.1007/s40265-014-0254-0 DP - EBSCOhost IS - 11 KW - Tourette Syndrome -- Drug Therapy Antipsychotic Agents -- Therapeutic Use Human Systematic Review -- Utilization Tourette Syndrome -- Epidemiology Genomics Randomized Controlled Trials -- Utilization Double-Blind Studies -- Utilization Databases -- Utilization N1 - research; systematic review; tables/charts. Journal Subset: Australia & New Zealand; Biomedical; Peer Reviewed. Special Interest: Evidence-Based Practice; Pediatric Care; Psychiatry/Psychology. NLM UID: 7600076. PMID: NLM25034359. PY - 2014 SN - 0012-6667 SP - 1177-1193 ST - The Role of Atypical Antipsychotics for Treatment of Tourette's Syndrome: An Overview T2 - Drugs TI - The Role of Atypical Antipsychotics for Treatment of Tourette's Syndrome: An Overview UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=103978242&site=ehost-live&scope=site VL - 74 ID - 478 ER - TY - JOUR AB - Background: Chronic, recurrent abdominal pain is common among children and adolescents. It interferes with everyday life, causes absence from school, and leads to frequent medical consultations, often involving burdensome diagnostic testing and protracted attempts at treatment. Method: Selective review of the literature. Results: Organic causes should be ruled out with a thorough medical history and physical examination and a small number of laboratory tests. The pediatric Rome III criteria include valid diagnostic criteria for functional abdominal pain in childhood. The available data imply that this condition is best treated with cognitive behavioral therapy, rather than with medications or dietary measures. Conclusion: A systematic approach to chronic recurrent abdominal pain in children and adolescents is key to ruling out organic diseases while avoiding unnecessary tests and treatments. AD - Abteilung für Pädiatrische Gastroenterologie und Hepatologie Dr. von Haunersches Kinderspital Ludwig-Maximilians-Universität München Lindwurmstr. 4 80337 München AN - 104590024. Language: English. Entry Date: 20120619. Revision Date: 20200708. Publication Type: Journal Article AU - Bufler, Philip AU - Gross, Martina AU - Uhlig, Holm H. DB - cin20 DO - 10.3238/arztebl.2011.0295 DP - EBSCOhost IS - 17 KW - Abdominal Pain -- In Infancy and Childhood Recurrence Education, Continuing (Credit) Child Abdominal Pain -- Etiology Abdominal Pain -- Symptoms Abdominal Pain -- Diagnosis Abdominal Pain -- Diet Therapy Abdominal Pain -- Psychosocial Factors Abdominal Pain -- Drug Therapy Abdominal Pain -- Therapy Severity of Illness Indices Unnecessary Procedures Dyspepsia Irritable Bowel Syndrome Patient History Taking Algorithms Cognitive Therapy N1 - algorithm; CEU; exam questions; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Continental Europe; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. PY - 2011 SN - 1866-0452 SP - 295-303 ST - Recurrent Abdominal Pain in Childhood T2 - Deutsches Aerzteblatt International TI - Recurrent Abdominal Pain in Childhood UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104590024&site=ehost-live&scope=site VL - 108 ID - 587 ER - TY - JOUR AD - Migraine Association, Kragujevac UK Royal Sussex Hospital, Kragujevac UK Forth valley Royal Hospital, Kragujevac UK AN - 104100522. Language: English. Entry Date: 20140718. Revision Date: 20200708. Publication Type: Journal Article AU - Burn, D. AU - Markham, R. AU - Lipscombe, S. AU - Abu-Arafeh, I. DB - cin20 DO - 10.1186/1129-2377-14-S1-P31 DP - EBSCOhost KW - Migraine -- Psychosocial Factors -- In Infancy and Childhood Migraine -- Symptoms -- In Infancy and Childhood Human Child Adolescence Random Sample Migraine -- Organizations Questionnaires Data Analysis Software Male Female Child, Preschool Infant Absenteeism Patient Attitudes Academic Performance Quality of Life N1 - abstract; research. Supplement Title: Feb2013 Supplement. Journal Subset: Biomedical; Continental Europe; Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. Special Interest: Pain and Pain Management; Pediatric Care. NLM UID: 100940562. PY - 2013 SN - 1129-2369 SP - 1-1 ST - Me and my migraine: impact survey for children and young people...The European Headache and Migraine Trust International Congress, London, UK, 20-23 September 2012 T2 - Journal of Headache & Pain TI - Me and my migraine: impact survey for children and young people...The European Headache and Migraine Trust International Congress, London, UK, 20-23 September 2012 UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104100522&site=ehost-live&scope=site VL - 14 ID - 533 ER - TY - JOUR AB - Objective: To assess the impact of parental migraine on adolescents (aged 13‐21 years) living within the parental home from the adolescent's perspective. Background: Family members are affected by their parent's migraine. We surveyed adolescents on the social, academic, and emotional effects of their parent's migraine. Methods: The Chronic Migraine Epidemiology and Outcomes (CaMEO) study was a longitudinal Web‐based study with cross‐sectional modules designed to assess migraine symptoms, severity, frequency, and disability; migraine‐related consulting practices, healthcare utilization, medication use, comorbid health conditions, and family related burden associated with migraine. The Family Burden Module (adolescent version; FBM‐A) from the CaMEO study assessed parents with migraine and adolescent household members (dyads). Adolescents ranged in age from 13‐21 years and were living at home with their parent. The initial FBM‐A survey included 52 items covering five domains, which was refined and reduced by confirmatory factor analysis to 36 items covering four domains. Depression (9‐item Patient Health Questionnaire) and anxiety (7‐item Generalized Anxiety Disorder scale) were assessed. Item responses were stratified by parent migraine status (episodic migraine [EM], <15 headache days/month; chronic migraine [CM], ≥15 headache days/month). Frequencies of activities/events missed because of parental headache were categorized as ≥1 time or ≥4 times/previous 30 days. Results: The sample included 1,411 parent‐adolescent dyads (parent with EM, n = 1,243 [88.1%]; parent with CM, n = 168 [11.9%]). Burden due to a parent's migraine was reported in four domains based on 36 items including: Loss of Parental Support and Reverse Caregiving (5 items); Emotional Experience (13 items); Interference with School (4 items); and Missed Activities and Events (14 items). Across domains, perceived burden was greater for adolescents of parents with CM vs EM. Rates of moderate‐to‐severe anxiety symptoms were higher among adolescents of parents with CM (6.2 vs 11.3%, P = .01), while moderate‐to‐severe depression symptom rates were similar (5.5 vs 8.9%, P = .08). More adolescents of CM vs EM parents reported having a headache within the previous 3 months (P < .001). Conclusions: Parental migraine negatively impacts adolescent children, extending our understanding of the family burden of migraine and emphasizing the potential benefit to children of optimizing migraine care. AD - Montefiore Medical Center, Bronx, NY, USA Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA Headache Center and Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital, Cincinnati, OH, USA University of Cincinnati College of Medicine, Cincinnati, OH, USA UCSF Pediatric Headache Center and Division of Child Neurology, San Francisco, CA, USA Mayo Clinic, Phoenix, AZ, USA Vedanta Research, Chapel Hill, NC, USA Allergan plc, Irvine, CA, USA Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA AN - 128865141. Language: English. Entry Date: 20180405. Revision Date: 20190401. Publication Type: Article AU - Buse, Dawn C. AU - Powers, Scott W. AU - Gelfand, Amy A. AU - VanderPluym, Juliana H. AU - Fanning, Kristina M. AU - Reed, Michael L. AU - Adams, Aubrey Manack AU - Lipton, Richard B. DB - cin20 DO - 10.1111/head.13254 DP - EBSCOhost IS - 4 KW - Migraine Parental Attitudes Human Adolescence Adult Cross Sectional Studies Surveys Factor Analysis Questionnaires Scales Economic Aspects of Illness N1 - research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. Instrumentation: Depression (9-item Patient Health Questionnaire); (7-item Generalized Anxiety Disorder scale). NLM UID: 2985091R. PY - 2018 SN - 0017-8748 SP - 512-524 ST - Adolescent Perspectives on the Burden of a Parent's Migraine: Results from the CaMEO Study T2 - Headache: The Journal of Head & Face Pain TI - Adolescent Perspectives on the Burden of a Parent's Migraine: Results from the CaMEO Study UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=128865141&site=ehost-live&scope=site VL - 58 ID - 309 ER - TY - JOUR AB - Background: Fibromyalgia syndrome (FMS), a chronic widespread pain disorder, has been associated with various models of stress, including those that are workplace-related. In a previous study, we have documented the significantly increased prevalence of FMS among schoolteachers, as well as correlating symptoms with stressful workplace-related factors. In the current study, we have focused on the specific population of kindergarten teachers and attempted to document both the prevalence of FMS symptoms among this group and the association with stress and symptoms of posttrauma.Methods: All participants in the study were working as kindergarten teachers in Israel at the time of the study. Participants responded to a questionnaire documenting FMS symptom, which included the widespread pain index (WPI) and symptom severity scale (SSS), which together constitute the suggested American College of Rheumatology (ACR) FMS diagnostic criteria. Additional items on the questionnaire documented work motivation and performance, the occurrence of workplace-related stressful events, and the presence of posttraumatic symptoms.Results: 242 participants were recruited to the current study, including 239 (98.8%) females and 3 (1.2%) males. 62 individuals (25.6%) were found to fulfill ACR FMS criteria. Significant differences in work performance were found between teachers fulfilling FMS criteria compared with those not fulfilling criteria. Thus, FMS-positive teachers reported significantly higher rates of missing workdays, leaving work early, and a lower quality of interaction with children in the kindergarten and with peers and supervisors. Motivation to work was also significantly lower among these individuals. The widespread pain index (WPI) and symptom severity scale (SSS), which together constitute the components of the FMS diagnostic criteria, were positively correlated with both stress and posttraumatic symptoms. In addition, widespread pain, disordered sleep, difficulty with concentration, and other FMS symptoms were strongly correlated with many specific stressful factors at the workplace, including the number of children in the kindergarten, interaction with parents, lack of optimal physical conditions in the classrooms, and various demands on behalf of the educational system.Conclusion: FMS symptoms were found to be highly prevalent among Israeli kindergarten teachers, at a rate that greatly exceeds the prevalence in the general Israeli population. Stressful work-related events appear to be positively associated with the occurrence of FMS symptoms and may serve as triggers for their development. Healthcare professionals treating individuals engaged in this occupation should be vigilant for the occurrence of symptoms that are clinically associated with FMS and overlapping functional disorders. AD - Orot Israel College of Education, Rehovot, Israel Ben Gurion University of the Negev, Beersheeba, Israel Internal Medicine F, Sourasky Medical Center, Tel Aviv & Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel Internal Medicine H, Sourasky Medical Center, Tel Aviv & Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel AN - 146606121. Language: English. Entry Date: In Process. Revision Date: 20201219. Publication Type: journal article. Journal Subset: Biomedical AU - Buskila, Yafa AU - Chen-Levi, Tamar AU - Buskila, Dan AU - Jacob, Giris AU - Ablin, Jacob J. DB - cin20 DO - 10.1155/2020/3864571 DP - EBSCOhost N1 - Canada. NLM UID: 9612504. PMID: NLM33149798. PY - 2020 SN - 1203-6765 SP - 1-8 ST - Effects of Workplace-Related Factors on the Prevalence of Fibromyalgia among Israeli Kindergarten Teachers T2 - Pain Research & Management TI - Effects of Workplace-Related Factors on the Prevalence of Fibromyalgia among Israeli Kindergarten Teachers UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=146606121&site=ehost-live&scope=site ID - 165 ER - TY - JOUR AB - OBJECTIVE: To quantify the influence that workers' satisfaction with the firm's treatment of their disability claim and their health care provider has on workers' return to work (RTW) following onset of occupational LBP. METHODS: Using a prospective survey on back pain, medical treatment, and workers' satisfaction, we employ nonparametric and logistic analyses to see how satisfaction affects RTW. RESULTS: Workers' satisfaction with their employer's treatment of their disability claim is more important in explaining RTW than satisfaction with health care providers or expectations about recovery. Dissatisfied workers have worse return to work outcomes because they are more likely to have time lost claims and are more likely to have multiple spells of joblessness. CONCLUSIONS: Workers' RTW is more responsive to their satisfaction with how the firm treated their disability claim than with their satisfaction with the health care provider. Satisfaction of both types plays an important role in determining RTW. AD - Department of Economics, 183 FOB, Brigham Young University, Provo, UT 84602 AN - 106141915. Language: English. Entry Date: 20070831. Revision Date: 20150711. Publication Type: Journal Article AU - Butler, R. J. AU - Johnson, W. G. AU - Côté, P. DB - cin20 DP - EBSCOhost IS - 2 KW - Absenteeism Accidents, Occupational -- Psychosocial Factors Back Pain -- Psychosocial Factors Back Pain -- Rehabilitation Disability Evaluation Employer-Employee Relations Personal Satisfaction Worker's Compensation Accidents, Occupational -- Economics Adolescence Adult Aged Back Pain -- Economics Descriptive Statistics Health Services Research Insurance Kaplan-Meier Estimator Middle Age Occupational Diseases -- Economics Occupational Diseases -- Therapy Odds Ratio P-Value Prospective Studies Research Instruments Human N1 - research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. Instrumentation: Short Form 12 Health Survey (SF-12); Roland-Morris Disability Questionnaire (RDQ). NLM UID: 9504688. PMID: NLM17293761. PY - 2007 SN - 1076-2752 SP - 214-225 ST - It pays to be nice: employer-worker relationships and the management of back pain claims T2 - Journal of Occupational & Environmental Medicine TI - It pays to be nice: employer-worker relationships and the management of back pain claims UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106141915&site=ehost-live&scope=site VL - 49 ID - 712 ER - TY - JOUR AB - Background: The number of neuroimaging studies that examine chronic pain are relatively small, and it is clear that different chronic pain conditions activate diverse regions of the brain. Objective: Cancer patients presenting for diagnostic positron emission tomography (PET) imaging were asked to rate their spontaneous baseline pain score. Twenty patients with either no pain (NRS = 0) or with moderate to severe pain (NRS = 4) were invited to participate in this study to determine the difference in brain activity in cancer patients with moderate to severe chronic pain versus no pain. Study Design: Prospective, non-randomized, observational report. Setting: Academic medical center. Methods: Patients had a 2-D PET scan with the radionuclide 18F-fluoro-2-deoxyglucose (FDG) at a dose of approximately 20 mCi. Each individual raw PET scan was coregistered and normalized to standard stereotactic space. Differences in regional glucose metabolism were then statistically compared between patients with moderate-to-severe pain and patients with no pain. Results: The NRS pain score in the patients with moderate to severe pain (n = 11) was 4.5 [4.0-6.0] (median [interquartile range]) versus 0.0 [0.0-0.0] (p < 0.001) in the group with no pain (n = 9). Compared to patients with no pain, patients with moderate to severe pain had increased glucose metabolism bilaterally in the prefrontal cortex, BA 9-11. Unilateral activation was found in the right parietal precuneus cortex, BA 7. There were no areas of the brain in which there was decreased activity due to moderate to severe pain. Conclusions: Our results showing a preferential activation of the prefrontal cortex are consistent with results from studies showing that affective pain perception and negative emotions play an important part in the chronic pain experience. Limitations: This was not a randomized clinical trial. Patient medication was not controlled. AD - Department of Anesthesiology, Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA Rush University Medical Center, Chicago, IL. AN - 104925046. Language: English. Entry Date: 20110114. Revision Date: 20180914. Publication Type: journal article AU - Buvanendran, A. AU - Ali, A. AU - Stoub, T. R. AU - Kroin, J. S. AU - Tuman, K. J. AU - Buvanendran, Asokumar AU - Ali, Amjad AU - Stoub, Travis R. AU - Kroin, Jeffrey S. AU - Tuman, Kenneth J. DB - cin20 DP - EBSCOhost IS - 5 KW - Brain -- Radiography Brain Mapping Neoplasms -- Complications Pain -- Radiography Adolescence Adult Aged Chronic Disease Female Fludeoxyglucose F 18 -- Diagnostic Use Male Middle Age Pain -- Etiology Tomography, Emission-Computed Radioisotopes -- Diagnostic Use Young Adult Human N1 - research. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 100954394. PMID: NLM20859325. PY - 2010 SN - 1533-3159 SP - E337-42 ST - Brain activity associated with chronic cancer pain T2 - Pain Physician TI - Brain activity associated with chronic cancer pain UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104925046&site=ehost-live&scope=site VL - 13 ID - 616 ER - TY - JOUR AB - Objective: To study the prevalence of headache in a population of presumed healthy children, spanning Kindergarten through Grade 8. By contrast, the majority of previous studies focused on children who sought medical care for headache. Methodology: Questionnaires were administered to 245 school children and their parents to elicit the characteristics of the headaches from the children's and the parents' perspectives. In addition, a 'Draw-A Headache' was completed by each child. Results: The drawings confirmed the answers on the questionnaires that 89.4 percent of the children reported having headaches. About 55.5 percent of the parents recognized that their child had headaches, but 33.9 percent of children suffer headaches without their parents realizing the problem. A diagnosis of migraine was reported by parents of 4.9 percent of the children, yet 4.5 percent had symptoms of migraine (International Headache Society 1988) without a diagnosis. Conclusions: Headache is more prevalent among school children than predicted. The criteria used by physicians to diagnose pediatric headache may need to be expanded. A description by the child, whether verbal or artistic, communicates to the physician the disability produced by the headache more graphically than a parent's report. The disability of the headache, that is, what the child is prevented from doing, needs to be the focus rather than whether the headache features an aura or if the headache disappears with sleep. AD - Headache Care Center, Springfield, Missouri AN - 107314375. Language: English. Entry Date: 19970301. Revision Date: 20150711. Publication Type: Journal Article AU - Cady, R. K. AU - Farmer, K. U. AU - Griesemer, K. AU - Sable, J. DB - cin20 DP - EBSCOhost IS - 4 KW - Headache -- Epidemiology -- In Infancy and Childhood Questionnaires Descriptive Statistics Drawing Convenience Sample Headache -- Etiology Headache -- Symptoms Migraine Child, Preschool Child Human N1 - questionnaire/scale; research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 9010726. PY - 1996 SN - 1059-7565 SP - 312-318 ST - Prevalence of headache in children T2 - Headache Quarterly, Current Treatment & Research TI - Prevalence of headache in children UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=107314375&site=ehost-live&scope=site VL - 7 ID - 845 ER - TY - JOUR AB - Recent research has demonstrated that parental behaviors have an important impact upon child and adolescent pain outcomes. At present, however, we do not know which parents engage in particular behaviors and why. In 2 studies, the impact of parental catastrophizing about their child's pain upon parental tendency to stop their child's pain-inducing activity was investigated. Further, the mediating role of parental distress was explored. In study 1, a sample of schoolchildren (n=62; M=12.48 years; SD=1.72) took part in a cold-pressor task. In study 2, a clinical sample of adolescents with chronic pain (n=36; M=15.68 years; SD=1.85) performed a 2-min walking task designed as a pain-inducing activity. In both studies, the accompanying parent was asked to watch their child performing the pain task. Findings revealed, for both studies, that parents with a high level of catastrophic thinking about their child's pain experienced more distress and a greater behavioral tendency of wanting to stop their child's pain-inducing activity. Further, parental feelings of distress mediated the relationship between parental catastrophic thinking and parents' tendency to restrict their child's activity. The findings are discussed in light of an affective-motivational conceptualization of pain and pain behavior. Parental catastrophizing was associated with parental tendency to restrict their child's engagement in a painful test, and this relationship was mediated by parental distress. AD - Department of Experimental-Clinical and Health Psychology, Ghent University, Belgium Research Institute for Psychology & Health, Utrecht, The Netherlands Centre for Pain Research, The University of Bath, Bath, UK Department of Experimental-Clinical and Health Psychology, Ghent University, Belgium. line.caes@ubent.be AN - 104982937. Language: English. Entry Date: 20110429. Revision Date: 20210115. Publication Type: journal article AU - Caes, L. AU - Vervoort, T. AU - Eccleston, C. AU - Vandenhende, M. AU - Goubert, L. AU - Caes, L. AU - Vervoort, T. AU - Eccleston, C. AU - Vandenhende, M. AU - Goubert, L. DB - cin20 DO - 10.1016/j.pain.2010.10.037 DP - EBSCOhost IS - 1 KW - Anxiety -- Psychosocial Factors Anxiety -- Rehabilitation Negotiation -- Methods Pain -- Psychosocial Factors Parent-Child Relations Parents -- Psychosocial Factors Adolescence Child Cold -- Adverse Effects Female Male Pain Measurement -- Methods Pain -- Etiology Pressure -- Adverse Effects Statistics Stress, Psychological -- Etiology Stress, Psychological -- Psychosocial Factors Stress, Psychological -- Rehabilitation N1 - research. Journal Subset: Biomedical; Continental Europe; Europe; Peer Reviewed. NLM UID: 7508686. PMID: NLM21126822. PY - 2011 SN - 0304-3959 SP - 212-222 ST - Parental catastrophizing about child's pain and its relationship with activity restriction: the mediating role of parental distress T2 - PAIN TI - Parental catastrophizing about child's pain and its relationship with activity restriction: the mediating role of parental distress UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104982937&site=ehost-live&scope=site VL - 152 ID - 598 ER - TY - JOUR AB - Objectives: This study aims to determine the frequency of juvenile fibromyalgia syndrome (JFMS) among children and adolescents in Çorum Province, Turkey, and its impact by comparing the levels of academic success, depression and quality of life (QoL) in individuals with and without JFMS. Patients and methods: This was a cross-sectional study on 476 children and adolescents (245 boys, 231 girls; mean age 13.81±2.3 years; range, 9 to 17 years). The control group (non-JFMS group) consisted of 105 age- and sex-matched healthy participants (75 girls, 30 boys; mean age 14.1±1.8 years; range; 9 to 17 years). Participants' sociodemographic data, parental information, and school achievement in addition to data on chronic illness and drug use were collected via questionnaires (depression and QoL). A tender point (TP) examination was performed on each participant. Results: Thirty-five (7.35%) of the participants (girls, n=25; boys, n=10) were diagnosed with JFMS. The number of minor JFMS diagnostic criteria, number of TPs, depression level and number of days the participants were absent from school were significantly higher in the JFMS group compared with the non-JFMS group (p<0.05). The mean grade point scores of the JFMS group were significantly lower than those of the non-JFMS group (p<0.05). The QoL subgroup scores as assessed by physical functioning, emotional functioning, social functioning and school-related problems of the JFMS group were significantly lower than the non-JFMS group (p<0.05). Age had a statistically significant negative correlation with QoL and school-related problems (r= -0.421, r= -0.494; p<0.05, respectively). Depression was negatively correlated with QoL and school-related problems (r= -0.672, r= -0.731; p<0.05, respectively). Conclusion: Juvenile fibromyalgia syndrome affects QoL and can lead to school absenteeism, poor academic performance, depression and anxiety among the school-age population. Early identification of JFMS and early intervention may be the most effective strategy for preventing problems in later life. AD - Department of Physical Medicine and Rehabilitation, Hitit University Faculty of Medicine, Çorum, Turkey Department of Physical Medicine and Rehabilitation, Pamukkale University, Faculty of Medicine, Denizli, Turkey AN - 142415988. Language: English. Entry Date: 20200403. Revision Date: 20200403. Publication Type: Article AU - ÇAgliyan TÜRk, Ayla AU - ŞAhİN, Füsun DB - cin20 DO - 10.5606/ArchRheumatol.2020.7458 DP - EBSCOhost IS - 1 KW - Fibromyalgia -- Epidemiology -- Turkey Fibromyalgia -- Complications -- In Infancy and Childhood Fibromyalgia -- Complications -- In Adolescence Academic Achievement Depression Quality of Life Human Turkey Male Female Child Adolescence Cross Sectional Studies Matched Case Control Prevalence Descriptive Statistics Questionnaires Physical Examination Functional Status Age Factors Students, Middle School Students, High School Early Diagnosis Early Intervention N1 - research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Middle East; Peer Reviewed. NLM UID: 101639000. PY - 2020 SN - 2618-6500 SP - 68-77 ST - Prevalence of Juvenile Fibromyalgia Syndrome Among Children and Adolescents and its Relationship With Academic Success, Depression and Quality of Life, Çorum Province, Turkey T2 - Archives of Rheumatology TI - Prevalence of Juvenile Fibromyalgia Syndrome Among Children and Adolescents and its Relationship With Academic Success, Depression and Quality of Life, Çorum Province, Turkey UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=142415988&site=ehost-live&scope=site VL - 35 ID - 193 ER - TY - JOUR AB - Neurofibromatosis type 1 (NF1) is one of the most common autosomal dominant disorders with a prevalence of one in 4,000 people worldwide, associated with many neurological comorbidities, such as headache. Despite the high prevalence of headache in this population, little data exist regarding the classification of headaches experienced by patients with NF1. Aim of this study is to verify the efficacy and safety of a nutraceutical complex containing Ginkgolide B/Coenzyme Q10/Riboflavin/Magnesium for prophylaxis in a sample of children affected by NF1 presenting migraine without aura. Ginkgolide B/Coenzyme Q10/Riboflavin/Magnesium complex was orally administered twice a day for 6 months, to 18 school-aged patients with NF1 and presenting symptoms of migraine without aura (10 M, mean age 8.4 ± 1.65). Each patient kept a journal to record: number, intensity (according VAS scale), duration of attacks and concomitant symptoms. In addition, the PedMIDAS scale was administered to assess migraine-related disability. To verify the efficacy of the association, we tested the starting frequency (T0) of headache after 6 months (T1) and then we calculated the migraine frequency delta percentage to express the decrease in monthly frequency. After treatment, a reduction was reported (p < 0.001) in all migraine outcomes (frequency, duration, intensity, and grade of disability). In conclusion, the present study should be considered as the first report on the efficacy and safety of nutraceutical complex containing Ginkgolide B/Coenzyme Q10/Riboflavin/Magnesium for the prophylaxis of migraine in children affected by NF1. Our findings suggest that headache symptoms should be considered a therapeutic target independent of primary disorder. AD - Clinic of Child and Adolescent Neuropsychiatry, Department of Mental Health, Physical and Preventive Medicine, Center for Childhood Headache, Second University of Naples, Via Sergio Pansini 5 PAD XI, 80131, Naples, Italy, marco.carotenuto@unina2.it. AN - 104112134. Language: English. Entry Date: 20140711. Revision Date: 20200708. Publication Type: journal article AU - Carotenuto, Marco AU - Esposito, Maria DB - cin20 DO - 10.1007/s10072-013-1403-z DP - EBSCOhost IS - 11 KW - Dietary Supplements -- Adverse Effects Migraine -- Diet Therapy Neurofibromatosis 1 -- Complications Child Female Hydrocarbons -- Therapeutic Use Human Organic Chemicals -- Therapeutic Use Magnesium -- Therapeutic Use Male Migraine -- Etiology Riboflavin -- Therapeutic Use Coenzyme Q Coenzyme Q -- Therapeutic Use N1 - research. Journal Subset: Biomedical; Continental Europe; Europe. NLM UID: 100959175. PMID: NLM23532548. PY - 2013 SN - 1590-1874 SP - 1905-1909 ST - Nutraceuticals safety and efficacy in migraine without aura in a population of children affected by neurofibromatosis type I T2 - Neurological Sciences TI - Nutraceuticals safety and efficacy in migraine without aura in a population of children affected by neurofibromatosis type I UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104112134&site=ehost-live&scope=site VL - 34 ID - 508 ER - TY - JOUR AB - Unlabelled: Pain-related self-efficacy and pain-related fear have been proposed as opposing predictors of pain-related functional outcomes in youth with chronic pain. Self-efficacy is a potential resiliency factor that can mitigate the influence that pain-related fear has on outcomes in youth with chronic pain. Drawing from theoretical assertions tested among adults with chronic pain, this study aimed to determine whether pain-related self-efficacy mediates the adverse influence of pain-related fear on functional outcomes in a sample of youth with chronic headache. In a cross-sectional design of 199 youth with headache, self-efficacy was strongly associated with fear, disability, school impairment, and depressive symptoms. Pain intensity and self-efficacy were only modestly related, indicating that level of pain has less influence on one's confidence functioning with pain. Self-efficacy partially mediated relationships between pain-related fear and both functional disability and school functioning but did not mediate the relationship between pain-related fear and depressive symptoms. These results suggest that confidence in the ability to function despite pain and fear avoidance each uniquely contributes to pain-related outcomes in youth with chronic headache. These results further suggest that treatment for chronic headache in youth must focus not only on decreasing pain-related fear but also on enhancing a patient's pain-related self-efficacy.Perspective: Pain-related self-efficacy is an important resiliency factor impacting the influence of pain-related fear on functional disability and school functioning in youth with headache. Enhancing self-efficacy may be a key mechanism for improving behavioral outcomes. Clinicians can reduce pain-related fear and enhance pain-related self-efficacy through interventions that encourage accomplishment and self-confidence. AD - Division of Pain Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts. Division of Pain Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts; Department of Psychiatry, Harvard Medical School, Boston, Massachusetts; PAIN Group, Boston Children's Hospital & Harvard Medical School, Boston, Massachusetts. Division of Pain Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts; PAIN Group, Boston Children's Hospital & Harvard Medical School, Boston, Massachusetts. Division of Pain Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts; Department of Psychiatry, Harvard Medical School, Boston, Massachusetts; PAIN Group, Boston Children's Hospital & Harvard Medical School, Boston, Massachusetts. Electronic address: Laura.Simons@childrens.harvard.edu. AN - 103821503. Language: English. Entry Date: 20150116. Revision Date: 20200708. Publication Type: journal article AU - Carpino, Elizabeth AU - Segal, Sharon AU - Logan, Deirdre AU - Lebel, Alyssa AU - Simons, Laura E. DB - cin20 DO - 10.1016/j.jpain.2014.01.493 DP - EBSCOhost IS - 5 KW - Fear Headache -- Physiopathology Headache -- Psychosocial Factors Pain -- Psychosocial Factors Self-Efficacy Achievement Adolescence Child Chronic Disease Cross Sectional Studies Depression -- Psychosocial Factors Female Human Male Models, Psychological Pain Measurement Psychological Tests Schools Severity of Illness Indices N1 - research. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Pain and Pain Management. Grant Information: K23 HD067202/HD/NICHD NIH HHS/United States. NLM UID: 100898657. PMID: NLM24462790. PY - 2014 SN - 1526-5900 SP - 527-534 ST - The interplay of pain-related self-efficacy and fear on functional outcomes among youth with headache T2 - Journal of Pain TI - The interplay of pain-related self-efficacy and fear on functional outcomes among youth with headache UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=103821503&site=ehost-live&scope=site VL - 15 ID - 488 ER - TY - JOUR AB - Students with chronic health conditions miss more school days than their peers and are at increased risk for performing worse on standardized tests and not completing a high school degree. University-based researchers, state government leaders, and a local county school system collaborated to use existing health and academic data to (1) evaluate the strength of the relationship between health status and school performance (absenteeism, grades) and (2) describe the health status of students who are chronically absent. Analyses included descriptive statistics, chi-square tests, negative binomial regression models, and estimated marginal means. The most common health conditions among the 3,663 kindergarten through Grade 12 students were ADD (attention deficit disorder)/ADHD (attention deficit hyperactivity disorder), asthma, migraine headaches, mental health conditions, and eczema/psoriasis/skin disorders. After controlling for covariates, having asthma or a mental health diagnosis was positively associated with absences; and having an ADD/ADHD or mental health diagnosis was negatively associated with GPA (grade point average). Chronically absent students had significantly lower GPAs, and a higher number of health conditions than other students. The success of this demonstration project encourages strengthening existing collaborations and establishing new multidisciplinary partnerships to analyze existing data sources to learn more about the relationship between student health and academic achievement. Moreover, connecting health status to academic achievement might be a chief tactic for advocating for additional resources to improve the care and management of chronic disease conditions among students. AD - University of Maryland School of Public Health, College Park, MD, USA Garrett County Board of Education, Oakland, MD, USA Garrett County Public Schools, Accident, MD, USA AN - 148516931. Language: English. Entry Date: 20210216. Revision Date: 20210216. Publication Type: Article AU - Carter-Pokras, Olivia D. AU - Bugbee, Brittany A. AU - Gold, Robert S. AU - Lauver, Phillip E. AU - Aiken, Rebecca AU - Arria, Amelia M. DB - cin20 DO - 10.1177/1524839919862796 DP - EBSCOhost IS - 2 KW - Health Status School Health Services Academic Achievement Human Absenteeism Students, Elementary Descriptive Statistics Chi Square Test Students, Middle School Students, High School Attention Deficit Hyperactivity Disorder Asthma Migraine Mental Disorders Eczema Child Adolescence Child, Preschool Chronic Disease N1 - research; tables/charts. Journal Subset: Biomedical; Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Health Promotion/Education; Nursing; Peer Reviewed; Public Health; USA. NLM UID: 100890609. PY - 2021 SN - 1524-8399 SP - 193-203 ST - Utilizing Student Health and Academic Data: A County-Level Demonstration Project T2 - Health Promotion Practice TI - Utilizing Student Health and Academic Data: A County-Level Demonstration Project UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=148516931&site=ehost-live&scope=site VL - 22 ID - 145 ER - TY - JOUR AB - BACKGROUND: Headache has been described as a factor with significant negative impact on the quality of life of school-aged children with a high risk of developing in chronic and persistent form in adulthood. Among other headache associated triggers or aggravating factors, lifestyle and obesity has been investigated, but results are still conflicting. OBJECTIVE: To evaluate the prevalence of headache in school-aged children and its relationship to anthropometric characteristics, lifestyle, and quality of life. METHODS: A cross-sectional study was conducted in six schools located in two cities in southern Brazil, involving 750 students aged 7 to 14 years. Information was collected on sociodemographic characteristics, clinical variables (presence of headache and menarche), anthropometric data, lifestyle, and quality of life. RESULTS: A total of 185 (24.7%) students reported having headache crises in the last 3 months. Among students aged 10 to 14 years, presence of headache was associated with female sex, affecting 32.2% of girls vs. 23.3% of boys (p = 0.042, chi-square test). Anthropometric parameters (data on overweight/obesity) were consistent with national prevalence rates, and there was no association between Body Mass Index (BMI) and headache. Regarding lifestyle, 2.0% of students reported smoking and 1.6% consuming alcohol occasionally, and neither was associated with headache. Quality of life, especially aspects of social life, appeared to be affected by the presence of headache. CONCLUSION: This study found a high prevalence of headache in school-aged children, which was associated with female students aged 10-14 years and quality of life. AD - Food and Nutrition Research Center. Hospital de Clínicas de Porto Alegre. Universidade Federal do Rio Grande do Sul. Porto Alegre. Rio Grande do Sul. Brazil. AN - 104123572. Language: English. Entry Date: 20141010. Revision Date: 20150710. Publication Type: Journal Article AU - Castro, Kamila AU - Rockett, Fernanda C. AU - Billo, Maira AU - Oliveira, Gabriela T. AU - Klein, Luciana S. AU - Parizotti, Cristiane S. AU - Perla, Alexandre S. AU - Perry, Ingrid D. S. DB - cin20 DO - 10.3305/nh.2013.28.5.6729 DP - EBSCOhost IS - 5 KW - Headache -- Epidemiology Life Style Nutritional Status Quality of Life Adolescence Body Height Body Mass Index Body Weight Brazil Child Cross Sectional Studies Female Human Male Prevalence N1 - research. Journal Subset: Biomedical; Continental Europe; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. Special Interest: Nutrition. NLM UID: 9100365. PMID: NLM24160214. PY - 2013 SN - 0212-1611 SP - 1546-1551 ST - Lifestyle, quality of life, nutritional status and headache in school-age children T2 - Nutricion Hospitalaria TI - Lifestyle, quality of life, nutritional status and headache in school-age children UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104123572&site=ehost-live&scope=site VL - 28 ID - 517 ER - TY - JOUR AB - Background: Headache is a widespread disorder in children, but little is known about the headache prevalence in northwest Italy, on less frequent migraine equivalents, family history, and treatment habits in children.Method: This is an epidemiologic population-based study of a representative sample of children aged 3 to 11 years, conducted in Alba, Italy. We used a self-administered questionnaire to acquire information on gender, age, headache, possible migraine equivalents, family history for various diseases, and treatment habits.Results: We distributed the questionnaire to 1152 children, and a total of 649 questionnaires were successfully completed. In the preschool age, 10.3% (seven boys and nine girls) of children suffered from headache. In school-age children, the prevalence of headache was 31.4% (75 boys and 80 girls; 27% in 6 year olds and 41% at age 9 years). We found a significant correlation between headache and abdominal pain in the entire sample and with cyclic vomiting syndrome and dizziness in school-age children only. Headache correlated significantly with a family history of headache, thyroid diseases, diabetes, hypertension, and vascular diseases. Headache was treated with drugs, primarily paracetamol, in 60 of the 171 (35%) children who reported headache and in 61% of the children with migraine; no subjects were treated with triptans.Conclusions: Headache is widespread in children, with a high prevalence of associated symptoms and family history for many other headache-related disorders. AN - 109676956. Language: English. Entry Date: 20150923. Revision Date: 20160406. Publication Type: journal article. Journal Subset: Biomedical AU - Cavestro, Cinzia AU - Montrucchio, Francesca AU - Benci, Paola AU - Pompilio, Domenica AU - Mandrino, Silvia AU - Cencio, Pier Giuseppe AU - Frigeri, Maria Cristina AU - Di Pietrantonj, Carlo DB - cin20 DO - 10.1016/j.pediatrneurol.2014.05.022 DP - EBSCOhost IS - 3 N1 - USA. Special Interest: Pediatric Care. NLM UID: 8508183. PMID: NLM24993247. PY - 2014 SN - 0887-8994 SP - 348-353 ST - Headache prevalence and related symptoms, family history, and treatment habits in a representative population of children in Alba, Italy T2 - Pediatric Neurology TI - Headache prevalence and related symptoms, family history, and treatment habits in a representative population of children in Alba, Italy UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=109676956&site=ehost-live&scope=site VL - 51 ID - 475 ER - TY - JOUR AB - This study presents a method for quantitative evaluation of the congruence between patients' representations and teachers' scientific knowledge, which is used as the standard of assessment. First, the patients' knowledge and the teachers' scientific concepts before a back school (BS) programme were compared (T0). Then the evolution of patients' knowledge at 1 month (T1) and 1 year (T2) after the teaching was evaluated. Patients' knowledge was assessed blind by a multidisciplinary panel of nine independent judges. Mean scores were computed for each set of data (T0,T1,T2); these scores were then submitted to an analysis of variance. The results showed an important gap between patients and teachers before BS with an improvement after the teaching. Knowledge referring to know-how and/or attitudes evolved differently when compared to theoretical knowledge. AD - Division of Rheumatology, Hôpital Beau-Séjour, Geneva, Switzerland Division of Rheumatology, Hopital Beau-Sejour, 1211 Geneva 14, Switzerland AN - 107376253. Language: English. Entry Date: 19960701. Revision Date: 20190923. Publication Type: journal article AU - Cedraschi, C. AU - Reust, P. AU - Lorenzi-Cioldi, F. AU - Vischer, T. L. AU - Cedraschi, C. AU - Reust, P. AU - Lorenzi-Cioldi, F. AU - Vischer, T. L. DB - cin20 DP - EBSCOhost IS - 3 KW - Patient Education Health Knowledge -- Evaluation Low Back Pain Chronic Pain Low Back Pain -- Therapy Time Factors Discriminant Analysis Coefficient Alpha Analysis of Variance Adolescence Adult Middle Age Aged Male Female Human N1 - research; tables/charts. Journal Subset: Core Nursing; Europe; Health Promotion/Education; Nursing; Peer Reviewed; UK & Ireland. NLM UID: 8406280. PMID: NLM8788352. PY - 1996 SN - 0738-3991 SP - 235-246 ST - The gap between back pain patients' prior knowledge and scientific knowledge and its evolution after a back school teaching programme: a quantitative evaluation T2 - Patient Education & Counseling TI - The gap between back pain patients' prior knowledge and scientific knowledge and its evolution after a back school teaching programme: a quantitative evaluation UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=107376253&site=ehost-live&scope=site VL - 27 ID - 847 ER - TY - JOUR AB - Background: Lumbar disc disease is one of the most important cause of lumbar radiculopathy. Even a normal healthy disc may rupture by sudden heavy load if it is beyond the tensile limit of annulus fibrous. The lumbo-sacral radicular pain due to lumbar disc herniation, is responsible for DALY loss in terms of work absenteeism and disability. For a developing country like ours it's a major health issue often ignored as patients don't require hospitalization. In a developing country a cost effective method which is not increasing any out of pocket expenditure for the patient for relief from the lumbar disc disease suffering must be hailed as a boon considering its effectiveness as well as feasibility of administration everywhere. Method Starting March 18 till Dec 19 records of patients coming as per our eligibility criteria after IEC clearance were evaluated for the effectiveness of straight leg raising technique with data being analyzed using the measures of central tendency and other appropriate tests. Results Out of 72 patients 69 achieved improvement in pain while 68 achieved improvement in their ability to move along. Conclusion Given the zero cost of exercise technique this technique is an easy to master technique. if larger studies can validate our findings this can be taken at grass root levels to bolster the health care systems and train frontline health care service givers so that last mile beneficiary too gets the benefit and relief from chronic pain owing to lumbar disease. AD - Assistant Professor, Department of Physical Medicine and Rehabilitation, Rajendra Institute of Medical Sciences, Ranchi Assistant Professor, Department of Preventive and Social Medicine, Patliputra Medical College and Hospital, Dhanbad AN - 145647384. Language: English. Entry Date: 20200929. Revision Date: 20201002. Publication Type: Article AU - Chaitanya, Amit AU - Rana, Rishabh Kumar DB - cin20 DO - 10.47203/ijch.2020.v32i02.013 DP - EBSCOhost IS - 2 KW - Lumbar Vertebrae -- Pathology Spinal Diseases -- Epidemiology -- India Spinal Diseases -- Therapy Stretching -- Economics Lower Extremity Exercises -- Economics Cost Benefit Analysis Treatment Outcomes Human Child Adolescence Adult Middle Age Aged Male Female India Retrospective Design Record Review Nonexperimental Studies Descriptive Research N1 - research; tables/charts. Journal Subset: Asia; Health Promotion/Education; Peer Reviewed; Public Health. PY - 2020 SN - 2248-9509 SP - 371-377 ST - Evaluating the Lumbar Nerve Root Stretching using Straight Leg Raising Technique A cost effective treatment option for patients of lumbar disc disease T2 - Indian Journal of Community Health TI - Evaluating the Lumbar Nerve Root Stretching using Straight Leg Raising Technique A cost effective treatment option for patients of lumbar disc disease UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=145647384&site=ehost-live&scope=site VL - 32 ID - 191 ER - TY - JOUR AB - Importance: Sinusitis is the most common otolaryngologic complaint in children with cystic fibrosis (CF). However, basic knowledge about the effect of sinusitis on these children is lacking.Objective: To evaluate the incidence and quality-of-life impact of chronic rhinosinusitis (CRS) in an unbiased cohort of children with CF.Design, Setting, and Participants: Survey study of consecutive pediatric patients with CF presenting for routine quarterly evaluation at a tertiary CF clinic at an academic pediatric hospital. Surveys were completed during the period from December 2012 to January 2013.Main Outcomes and Measures: Surveys designed to assess major criteria for diagnosis of CRS and a validated pediatric sinonasal quality-of-life instrument, the Sinonasal-5 (SN-5). Statistical analysis was performed to evaluate association between demographic features and survey responses.Results: Of the 102 consecutive eligible patients, 47 children (46%) aged 2 to 20 years (mean [SD] age, 12.9 [5.6] years; 24 [51%] female) completed the surveys. Depending on the exact diagnostic criteria used, 5 (11%) to 18 (38%) of children with CF had CRS. Mean domain (2.16; 95% CI, 2.02-2.30) and overall visual-analog scale (8.26; 95% CI, 8.01-8.51) scores on the SN-5 were consistent with minimal effect on quality of life and comparable to historical posttreatment scores. Mean scores on nasal obstruction (3.07; 95% CI, 2.80-3.34) and sinusitis (2.68;; 95% CI, 2.42-2.94) were the most affected domains, whereas allergy (1.83; 95% CI, 1.65-2.01), emotional disturbance (1.76; 95% CI, 1.56-1.96), and activity restriction (1.43; 95% CI, 1.31-1.57) were minimally affected. Children with a diagnosis of CRS had higher mean SN-5 scores (2.60; 95% CI, 2.31-2.89 vs 2.05; 95% CI, 1.90-2.20; difference of 0.55; 95% CI, 0.29-0.80). Twenty-five patients (53%) had undergone some treatment for sinusitis. There was no association between SN-5 score and CRS treatment history.Conclusions and Relevance: In this study, the incidence of symptomatic CRS was high, but quality-of-life impact was relatively low among children with CF. Use of standardized assessment scales, including consensus diagnostic criteria and validated quality-of-life surveys, may be helpful to guide referral and management decisions. AD - Division of Pediatric Otolaryngology, Department of Otolaryngology-Head and Neck Surgery, University of California, San Francisco Division of Pulmonary and Sleep Medicine, Seattle Children's Hospital, Seattle, Washington Division of Pediatric Otolaryngology, Seattle Children's Hospital, Seattle, Washington AN - 117565502. Language: English. Entry Date: 20170710. Revision Date: 20180502. Publication Type: journal article AU - Chan, Dylan K. AU - McNamara, Sharon AU - Park, Jason S. AU - Vajda, Jame AU - Gibson, Ronald L. AU - Parikh, Sanjay R. DB - cin20 DO - 10.1001/jamaoto.2016.0979 DP - EBSCOhost IS - 8 KW - Rhinitis -- Complications Sinusitis -- Complications Quality of Life Cystic Fibrosis -- Complications Child, Preschool Child Nasal Obstruction -- Etiology Prospective Studies Olfaction Disorders -- Etiology Young Adult Visual Analog Scaling Adolescence Female Facial Pain -- Etiology Age Factors Chronic Disease Male Human N1 - pictorial; research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 101589542. PMID: NLM27228505. PY - 2016 SN - 2168-6181 SP - 743-749 ST - Sinonasal Quality of Life in Children With Cystic Fibrosis T2 - JAMA Otolaryngology-Head & Neck Surgery TI - Sinonasal Quality of Life in Children With Cystic Fibrosis UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=117565502&site=ehost-live&scope=site VL - 142 ID - 397 ER - TY - JOUR AB - Objective: To assess dietary compliance to Gluten Free Diet (GFD), to identify barriers to compliance and to study the impact of diet on the psychosocial behavior of children with celiac disease.Methods: Children diagnosed with celiac disease and followed up for more than 6 months, were assessed for dietary compliance. After this assessment, patients were subjected to an interview, consisting of self administered questionnaire, by the investigator who was blinded to initial results of initial assessment. Psychosocial parameters were assessed by standard Pediatric Symptom Checklist (PSC) containing 35 items. Dietary compliant and non-compliant groups were compared for assessed factors affecting the dietary compliance. Cases were also compared to healthy controls for psychosocial parameters.Results: A total of 70 patients were assessed for dietary compliance: 53(75%) were found to be dietary compliant, 13(18%) dietary non-compliant while 4 had doubtful dietary compliance. Final analysis was done for 64 patients who had complete assessment; 4 patients with doubtful dietary compliance and 2 patients who had incomplete assessment, were excluded. Dietary compliance was higher in younger children (>80%) compared to adolescents (44%); in children with higher maternal education; in parents having better knowledge and understanding of disease. Compliance was better in nuclear families; with less number of siblings (68.3% of compliant had <2 siblings compared to 23% in non-compliant); in families with higher per capita income. Dietary compliance was also better in children who presented with typical symptoms of celiac disease (72% of dietary compliant presented with loose motion as presenting symptom compared to only 15% in non-compliant). Celiac children had problems related to adjustment such as difficulty in maintaining diet at school, restaurants, trips, etc.45% patients complained that their teachers don't understand the nature of their disease. Pediatric Symptom Checklist (PSC) score was above cut-off in 4 children of dietary non-compliant group. Few individual PSC items such as complaints of aches and pains; is irritable, angry; does not listen to the rules, blames other for mistakes; teases others; refuses to share, were more common in celiac children than control.Conclusions: Noncompliance to gluten free dietary regimen is seen in 18 % of cases. Dietary noncompliance is more common in the adolescent age group, in joint families and those who have more number of siblings. Dietary restrictions have impact on child's social activities and thus psychosocial parameters (PSC score) are better in the dietary compliant group. AD - Division of Gastroenterology, Department of Pediatrics, Lady Hardinge Medical College and Associated Kalawati Saran Children Hospital, New Delhi, India Division of Gastroenterology, Department of Pediatrics, Lady Hardinge Medical College and Associated Kalawati Saran Children Hospital, New Delhi, India. AN - 105039479. Language: English. Entry Date: 20101029. Revision Date: 20200708. Publication Type: journal article AU - Chauhan, J. C. AU - Kumar, P. AU - Dutta, A. K. AU - Basu, S. AU - Kumar, A. AU - Chauhan, J. C. AU - Kumar, Praveen AU - Dutta, A. K. AU - Basu, Srikanta AU - Kumar, Arun DB - cin20 DO - 10.1007/s12098-010-0092-3 DP - EBSCOhost IS - 6 KW - Celiac Disease -- Diet Therapy Celiac Disease -- Psychosocial Factors Diet, Gluten-Free Patient Compliance Adolescence Case Control Studies Celiac Disease -- Diagnosis Child Child, Preschool Human India Poverty Questionnaires Risk Assessment Risk Factors N1 - research. Journal Subset: Asia; Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed. NLM UID: 0417442. PMID: NLM20532683. PY - 2010 SN - 0019-5456 SP - 649-654 ST - Assessment of dietary compliance to gluten free diet and psychosocial problems in Indian children with celiac disease T2 - Indian Journal of Pediatrics TI - Assessment of dietary compliance to gluten free diet and psychosocial problems in Indian children with celiac disease UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105039479&site=ehost-live&scope=site VL - 77 ID - 626 ER - TY - JOUR AB - Background: Recent evidence has demonstrated a high rate of return to running after hip arthroscopy for femoroacetabular impingement at short-term follow-up. The midterm outcomes and rates of continued running of these patients are unknown. Purpose: To evaluate midterm rates of return to running and outcomes after hip arthroscopy. Study Design: Case series; Level of evidence, 4. Methods: Data were prospectively collected for patients who underwent hip preservation surgery between July 2008 and November 2011. Patients were excluded for preoperative Tönnis osteoarthritis grade ≥2, previous ipsilateral hip conditions or hip surgery, or workers' compensation status. All patients who participated in mid- to long-distance running before their surgery and intended on returning after their operation were considered for inclusion. Preoperative and minimum 5-year postoperative measures for the following patient-reported outcome scores (PROs) were necessary for inclusion in the final cohort: the modified Harris Hip Score, Non-arthritic Hip Score, Hip Outcome Score–Sports Specific Subscale, and visual analog scale (VAS) for pain. All patients were counseled about the risks of continued running after hip arthroscopy. Results: Sixty patients (62 hips) were eligible for inclusion, of which 50 (83.3%; 52 hips) had minimum 5-year follow-up. There were 10 male hips and 42 female hips. Mean ± SD age at surgery was 32.4 ± 12.4 years (range, 14.9-62.4), and mean body mass index was 22.9 ± 3.2 (range, 17.7-30.1). Latest follow-up was recorded at a mean 69.3 ± 8.5 months (range, 60.0-92.1 months). Level of competition included 39 recreational, 7 high school, 4 collegiate, and 2 professional athletes. There were significant improvements in all PROs and VAS scores preoperatively to latest follow-up. Mean modified Harris Hip Score improved from 67.5 to 88.2; mean Non-arthritic Hip Score, from 65.9 to 88.3; mean Hip Outcome Score–Sports Specific Subscale, from 49.5 to 81.0; and mean VAS, from 5.2 to 1.5. At latest follow-up, patient satisfaction was 8.4. Thirty-nine patients (78.0%, 41 hips) had returned to running postoperatively. When stratified by level of competition, 79% (31 of 39) of recreational, 100% (7 of 7) of high school, 50% (2 of 4) of collegiate, and 50% (1 of 2) of professional athletes returned to running. Conclusion: Hip arthroscopy for all levels of runners is associated with a significant increase in PROs and a low risk of complications. The rate of return to running is moderately high after hip arthroscopy at midterm follow-up. Hip arthroscopy may be considered for runners presenting with symptoms of femoroacetabular impingement that fail nonoperative treatments. Patients should be educated on the rate of return to running over time and the risks of continued running after hip arthroscopy. AD - BoulderCenter for Orthopedics, Boulder, Colorado, USA University of Illinois at Chicago, Chicago, Illinois, USA Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA Sovereign Medical Group, Glen Rock, New Jersey, USA American Hip Institute, Des Plaines, Illinois, USA AN - 136492913. Language: English. Entry Date: 20190521. Revision Date: 20190529. Publication Type: Article AU - Chen, Austin W. AU - Craig, Matthew J. AU - Yuen, Leslie C. AU - Ortiz-Declet, Victor AU - Maldonado, David R. AU - Domb, Benjamin G. DB - cin20 DO - 10.1177/0363546519836429 DP - EBSCOhost IS - 6 KW - Treatment Outcomes -- Evaluation Sports Re-Entry -- Evaluation Running Arthroscopy Hip Labram Tear -- Surgery Femoracetabular Impingement -- Surgery Funding Source Human Running Injuries Prospective Studies Patient-Reported Outcomes Male Female Descriptive Statistics Adolescence Adult Middle Age Patient Satisfaction Athletes Sporting Events Patient Assessment Rehabilitation Two-Tailed Test T-Tests Wilcoxon Signed Rank Test Chi Square Test Fisher's Exact Test Hip Labram Tear -- Diagnosis Acetabuloplasty Surgical Debridement Postoperative Complications Reoperation Scales N1 - research; tables/charts. Journal Subset: Allied Health; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Instrumentation: Modified Harris Hip Score (MHHS); Non-Arthritic Hip Score (NAHS); Visual Analog Scale (VAS) for pain; Hip Outcome Score - Sports Specific Subscale (HOS-SSS). Grant Information: This study was supported by Arthrex, DJO, ATI, Kaufman Foundation, Pacira Pharmaceuticals.. NLM UID: 7609541. PY - 2019 SN - 0363-5465 SP - 1459-1466 ST - Five-Year Outcomes and Return to Sport of Runners Undergoing Hip Arthroscopy for Labral Tears With or Without Femoroacetabular Impingement T2 - American Journal of Sports Medicine TI - Five-Year Outcomes and Return to Sport of Runners Undergoing Hip Arthroscopy for Labral Tears With or Without Femoroacetabular Impingement UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=136492913&site=ehost-live&scope=site VL - 47 ID - 243 ER - TY - JOUR AB - This study examined how maternal chronic illnesses may affect children’s academic achievement through parental involvement. A total of 189 mothers diagnosed with chronic illnesses, such as multiple sclerosis, diabetes, cancer, HIV/AIDS, chronic pain, asthma, myelodysplasic syndrome, and fibromyalgia, and with a child in middle school or high school (age 10-18 years) completed questionnaires assessing the demands of illness on family functioning, parental involvement, and the child’s academic functioning. The results suggested that the majority of children of mothers with chronic illness were able to function adequately in terms of academic achievement. However, children’s academic functioning might be at risk when family functioning was more disrupted as the result of maternal illness. Children’s grades were negatively related to levels of demands of illness on family functioning. Levels of illness demands were negatively related to parental self-efficacy. Moreover, parental self-efficacy attenuated the effects of disruption in normal family functioning on children’s academic achievement. AD - The Graduate Center, The City University of New York, New York, NY, USA Queens College, The City University of New York, Flushing, NY, USA AN - 86975018. Language: English. Entry Date: 20130417. Revision Date: 20200507. Publication Type: Article AU - Chen, Yung-Chi AU - Fish, Marian C. DB - cin20 DO - 10.1177/0192513X12444081 DP - EBSCOhost IS - 5 KW - Mother-Child Relations Maternal Behavior Parenting Chronic Disease Academic Performance -- In Infancy and Childhood Human New York Female Child Adolescence Young Adult Adult Family Functioning Family Systems Theory Attitude to Illness Self-Efficacy Descriptive Statistics Chronic Disease -- Classification Clinical Assessment Tools Summated Rating Scaling Interview Guides Multiple Regression N1 - research; tables/charts. Journal Subset: Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Pediatric Care. Instrumentation: Demands of Illness Inventory (DOII); Parent Involvement in School Interview. NLM UID: 8005417. PY - 2013 SN - 0192-513X SP - 583-606 ST - Parental Involvement of Mothers With Chronic Illness and Children’s Academic Achievement T2 - Journal of Family Issues TI - Parental Involvement of Mothers With Chronic Illness and Children’s Academic Achievement UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=86975018&site=ehost-live&scope=site VL - 34 ID - 526 ER - TY - JOUR AB - Aim and objectives: To determine whether the virtual reality as a distracting intervention could reduce pain and fear in school‐age children receiving intravenous injections at an emergency department. Background: An intravenous injection is the most common invasive procedure that paediatric patients encounter in emergency department. School‐age children seldom show their fear or discomfort during the procedure which may be ignored. Design: A randomised controlled trial was conducted from December 2017–May 2018 and performed according to the CONSORT guidelines. Methods: One hundred and thirty‐six children aged 7–12 years were randomly allocated to receive either a routine intravenous injection procedure or one with an immersive virtual reality experience. Children were asked to rate their pain and fear along with their caregivers and nurses on the Wong–Baker FACES Pain Rating Scale and Children's Fear Scale, respectively. The time required for successful intravenous insertion was also assessed in the emergency department. Clinical trial registration was done (ClinicalTrials.gov.: NCT04081935). Results: Pain and fear scores were significantly lower in the virtual reality group, as were the children's ratings as perceived by their caregivers and nurses. The children's ratings of pain and fear were positively correlated with the caregivers' ratings and the nurses' ratings as well. The time required for successful intravenous insertion was significantly lower in the virtual reality group. Conclusion: Visual reality intervention can effectively reduce the pain and fear during intravenous procedure in school‐age children in emergency department. Relevance to clinical practice: The results of this study indicate the feasible clinical value of virtual reality interventions during the administration of intravenous injections in school‐age children in emergency departments. AD - Department of Nursing, National Yang‐Ming University Hospital, Yilan Taiwan School of Nursing, National Yang‐Ming University, Taipei Taiwan Department of Allied Health Education and Digital Learning, National Taipei University of Nursing and Health Sciences, Taipei Taiwan Department of Pediatrics, Taipei Veterans General Hospital, Taipei Taiwan AN - 141095709. Language: English. Entry Date: 20200111. Revision Date: 20210526. Publication Type: Article AU - Chen, Yen‐Ju AU - Cheng, Su‐Fen AU - Lee, Pi‐Chang AU - Lai, Chi‐Hsiu AU - Hou, I‐Ching AU - Chen, Chi‐Wen DB - cin20 DO - 10.1111/jocn.15088 DP - EBSCOhost IS - 3/4 KW - Emergency Service Injections, Intravenous -- Psychosocial Factors -- In Infancy and Childhood Distraction -- Methods Virtual Reality Fear -- Prevention and Control Pain -- Prevention and Control Treatment Outcomes Human Randomized Controlled Trials Random Assignment Child Wong-Baker FACES Pain Rating Scale Scales Taiwan Power Analysis Data Analysis Software Pearson's Correlation Coefficient T-Tests Male Female N1 - research; tables/charts; randomized controlled trial. Journal Subset: Peer Reviewed. Instrumentation: Wong-Baker FACES Pain Rating Scale; Children's Fear Scale (CFS). PY - 2020 SN - 0962-1067 SP - 503-510 ST - Distraction using virtual reality for children during intravenous injections in an emergency department: A randomised trial T2 - Journal of Clinical Nursing (John Wiley & Sons, Inc.) TI - Distraction using virtual reality for children during intravenous injections in an emergency department: A randomised trial UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=141095709&site=ehost-live&scope=site VL - 29 ID - 197 ER - TY - JOUR AD - Department of Psychiatry, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Taiwan; Department of Psychiatry, Faculty of Medicine, and Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Taiwan Department of Psychology, College of Humanities and Social Science, Kaohsiung Medical University, Taiwan Department of Psychiatry, Tainan Municipal Hospital, Taiwan Department of Psychology, National Cheng Kung University, Taiwan AN - 103978188. Language: English. Entry Date: 20140724. Revision Date: 20200708. Publication Type: Journal Article AU - Cheng-Fang, Yen AU - Lin, I. Mei AU - Tai-Ling, Liu AU - Huei-Fan, Hu AU - Chung-Ping, Cheng DB - cin20 DO - 10.1016/j.comppsych.2014.05.006 DP - EBSCOhost IS - 6 KW - Depression -- Psychosocial Factors -- In Adolescence Anxiety -- Psychosocial Factors -- In Adolescence Bullying Pain -- Psychosocial Factors -- In Adolescence Victims -- Psychosocial Factors -- In Adolescence Human Adolescence Taiwan Students, High School Questionnaires Structural Equation Modeling Self Report Summated Rating Scaling Scales Chi Square Test Male Female Descriptive Statistics Funding Source N1 - research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Psychiatry/Psychology. Instrumentation: Chinese version of the School Bullying Experience Questionnaire (C-SBEQ); Taiwanese Quality of Life Questionnaire for Adolescents (TQOLQA); Mandarin Chinese version of the Center for Epidemiological Studies-Depression Scale (MC-CES-D); Taiwanese version of the Multidimensional Anxiety Scale for Children (MASC-T). Grant Information: This study was partially supported by grants NSC 98- 2410-H-037-005-MY3 and 99-2314-B-037-028-MY2 awarded by the National Science Council, Taiwan (ROC) and grant KMUH 100-0R48 awarded by Kaohsiung Medical University Hospital.. NLM UID: 0372612. PMID: NLM24939705. PY - 2014 SN - 0010-440X SP - 1415-1421 ST - Mediating effects of depression and anxiety on the relationship between bullying involvement and pain problems among adolescents in Taiwan T2 - Comprehensive Psychiatry TI - Mediating effects of depression and anxiety on the relationship between bullying involvement and pain problems among adolescents in Taiwan UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=103978188&site=ehost-live&scope=site VL - 55 ID - 477 ER - TY - JOUR AB - Objective: Adolescents in Taiwan generally have a low level of knowledge concerning medications. This study evaluates a school-pharmacist partnership in Taiwan and describes the impact this association has on enhancing teachers' medication literacy and on their compliance with imparting this information to their students. Method: In 2013, the results from baseline and follow-up self-administered online structured questionnaire surveys received from 358 teachers in intervention primary and middle schools were compared with those received from 452 teachers in comparative primary and middle schools. Generalized Estimating Equation (GEE), regression analyses, and logistic regression analyses were conducted to examine the effects. Results: The results indicated that the partnership between schools and pharmacists had significantly enhanced teachers' knowledge, attitudes, self-efficacy, and skills concerning correct medication usage and pain medication literacy. In addition, the implementation of the school-pharmacist partnership had also significantly increased teachers' participation in the teaching of the proper uses of medication and in their implementation of school campaigns. Conclusion: The school-pharmacist partnership had a positive impact on enhancing teachers' medication literacy and participation in medication teaching in Taiwan. AD - Department of Health Developing and Marketing, Kainan University, Taoyuan, Taiwan Department of Health Promotion and Health Education, National Taiwan Normal University, Taipei, Taiwan Department of Pharmacy, Chia Nan University of Pharmacy and Science, Tainan, Taiwan Tri-Service General Hospital, Taiwan, Taipei, Taiwan Ministry of Health and Welfare, Taipei, Taiwan AN - 133587392. Language: English. Entry Date: 20181220. Revision Date: 20200525. Publication Type: Article AU - Chi, Hsueh-Yun AU - Chang, Fong-Ching AU - Huang, Li-Jung AU - Lee, Chun-Hsien AU - Pan, Ying-Chun AU - Yeh, Ming-Kung DB - cin20 DO - 10.1080/09687637.2017.1321620 DP - EBSCOhost IS - 6 KW - Health Literacy Pharmacists Collaboration -- Taiwan Education, Pharmacy -- Taiwan Professional Compliance Faculty-Student Relations Human Taiwan Prospective Studies Structured Questionnaires Surveys Schools, Middle Schools, Elementary Logistic Regression Professional Knowledge Faculty Attitudes Self-Efficacy Professional Competence Health Promotion Pain Management N1 - research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 9515845. PY - 2018 SN - 0968-7637 SP - 491-499 ST - Enhancing teachers' medication literacy and teaching through school-pharmacist partnership in Taiwan T2 - Drugs: Education, Prevention & Policy TI - Enhancing teachers' medication literacy and teaching through school-pharmacist partnership in Taiwan UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=133587392&site=ehost-live&scope=site VL - 25 ID - 275 ER - TY - JOUR AB - STUDY DESIGN.: A regionally representative telephone survey using a 2-stage randomization process. OBJECTIVE.: (1) To investigate the prevalence and consequence of neck pain in terms of disability and rate of absenteeism from work. (2) To describe the health services utilization pattern of neck pain subjects and to analyse the factors associated with neck pain and health services utilization pattern. SUMMARY OF BACKGROUND DATA.: There has been a lack of reliable information on the health service utilization pattern of neck pain subjects, the consequences and the patient perceived effectiveness of neck pain management in Hong Kong and Asian countries. METHODS.: Subjects were interviewed on the sociodemographic characteristics, occurrence and consequences of neck pain, and the health utilization pattern. A random sample of the respondents was re-interviewed 7 to 10 days after the initial interview, by an independent interviewer for the reliability check. RESULTS.: A total of 4640 subjects were interviewed. The 12-month prevalence was 64.6% (95% CI: 63.2%-66.0%). About 38.0% of these patients suffered from moderate to severe pain. Moreover, 17.7% of these subjects had to limit their social activities and 19% had to limit their work. About 25% of those subjects had consulted medical or health practitioners. Medical consultation is the majority and physiotherapy came second. Self-massage was the most preferred (83.3%) mode of self-care. Physiotherapy was regarded as the most effective health service, with 60% of the respondents' neck pain completely removed. Although most people chose self-massage to be the most effective self-care treatment, only one-third (30.2%) of them had their neck pain improved by less than a half. CONCLUSION.: Neck pain is highly prevalent with an increasing impact in Hong Kong. More than one-third of neck pain patients suffered from moderate to severe pain and around 20% of them had to limit their work. About 25% of neck pain patient have consulted medical or health professionals. Physiotherapy and private medical clinic were the 2 service providers with high percentage of perceived complete improvement. There was a general trend that more neck pain patients used complementary therapies. AD - From the *Department of Rehabilitation Sciences, Hong Kong Polytechnic University, Hung Hom, Hong Kong; and tHospital Authority Hong Kong. AN - 104927495. Language: English. Entry Date: 20110819. Revision Date: 20200708. Publication Type: Journal Article AU - Chiu, T. T. AU - Leung, A. S. AU - Lam, P. DB - cin20 DO - 10.1097/BRS.0b013e3181e219fd DP - EBSCOhost IS - 21 KW - Health Status Interviews -- Methods Neck Pain -- Epidemiology Neck Pain -- Therapy Patient Attitudes Surveys Absenteeism Adolescence Adult Aged Asians Community Health Services -- Utilization Female Hong Kong Hong Kong -- Ethnology Human Male Middle Age Neck Pain -- Ethnology Randomized Controlled Trials Referral and Consultation -- Trends Young Adult N1 - research; randomized controlled trial. Journal Subset: Allied Health; Biomedical; Peer Reviewed; USA. NLM UID: 7610646. PMID: NLM20838266. PY - 2010 SN - 0362-2436 SP - E1088-95 ST - Neck pain in Hong Kong: a telephone survey on consequences and health service utilization T2 - Spine (03622436) TI - Neck pain in Hong Kong: a telephone survey on consequences and health service utilization UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104927495&site=ehost-live&scope=site VL - 35 ID - 612 ER - TY - JOUR AB - Objective: The objective of this study was to identify patient‐reported school barriers and their associated impact in juvenile idiopathic arthritis (JIA). Methods: A cross‐sectional observational study of children aged 8 to 17, diagnosed with JIA, and followed in the rheumatology clinic/Alberta Children's Hospital was performed. Demographics, diagnosis, and disease course were obtained from health records. A questionnaire was administered to the child to assess the barriers experienced by JIA patients at school. The questionnaire collected information about school attendance/performance, impact of JIA symptoms (eg, pain and fatigue), physical challenges and accommodations, communication, participation and peers, and school support. Descriptive statistics were used to analyze the data. Results: A total of 98 children with JIA were recruited into the study. The median age of participants was 13 years (interquartile range 11‐15). The JIA subtypes in this cohort reflected the normal JIA distribution. Physical challenges at school (eg, gym, writing, and sitting for long periods of time) were reported by 42.1% of patients. Accommodations (eg, modified gym, accommodation letter, and computer access) were used by 23% of patients. The inability to participate in activities in class or outside with their peers occurred for 32.2% of patients and in gym for 40.7% of patients. Social concerns included embarrassment from talking about their illness, worry regarding being treated differently, and being told they were fabricating their illness. Conclusion: Children with JIA experienced barriers at school, especially physical challenges, with a need for accommodations in a proportion of children. Decreased participation and increased social anxiety were additional key barriers. AD - University of Calgary, Calgary Alberta, Canada AU - Chomistek, Kelsey AU - Johnson, Nicole AU - Stevenson, Rebeka AU - Luca, Nadia AU - Miettunen, Paivi AU - Benseler, Susanne M. AU - Veeramreddy, Dwaraka AU - Schmeling, Heinrike DB - cin20 DO - 10.1002/acr2.1023 DP - EBSCOhost IS - 3 N1 - Accession Number: 137359438. Language: English. Entry Date: In Process. Revision Date: 20190709. Publication Type: Article. PY - 2019 SN - 2578-5745 SP - 182-187 ST - Patient‐Reported Barriers at School for Children with Juvenile Idiopathic Arthritis T2 - ACR Open Rheumatology TI - Patient‐Reported Barriers at School for Children with Juvenile Idiopathic Arthritis UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=137359438&site=ehost-live&scope=site VL - 1 ID - 242 ER - TY - JOUR AB - Unlabelled: Accumulating evidence supports the concurrent association between parent distress and behavior and child functioning in the context of chronic pain, with existing longitudinal studies limited to a pediatric surgical context that identify parent catastrophizing as influential. In this study, we examined how parent factors assessed at a multidisciplinary pediatric pain clinic evaluation affect child psychological and functional outcomes over time. A cohort of 195 patients with chronic pain (ages 8-17 years) and their parents who presented for a multidisciplinary evaluation completed measures at baseline and at 4-month follow-up. Patients completed measures of pain catastrophizing, pain-related fear and avoidance, generalized anxiety, depressive symptoms, and functional disability. Parents completed measures of pain catastrophizing, pain-related fear and avoidance, and protective responses to child pain. Parent-reported child school functioning was also collected. Parent distress and behavior was concurrently associated with child distress and functioning at evaluation. After controlling for baseline child functioning, baseline parent avoidance and protective behavior emerged as significant predictors of child functioning at 4-month follow-up. Parent distress and behavior influence child distress and functioning over time and these findings identify key parent domains to target in the context of a child's pain treatment.Perspective: Parent behavior, specifically avoidance and protective responses, influence child distress and functioning over time. Child pain treatment interventions should include influential parent factors to ensure successful outcomes. AD - Division of Pain Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts Boston University School of Medicine, Boston, Massachusetts Research Division, VA Boston Healthcare System, Boston, Massachusetts Department of Psychiatry, Boston University School of Medicine, Boston, Massachusetts Department of Psychological and Brain Sciences, Boston University, Boston, Massachusetts Department of Psychiatry, Harvard Medical School, Boston, Massachusetts P.A.I.N. Group, Boston Children's Hospital and Center for Pain and the Brain, Boston, Massachusetts AN - 115742669. Language: English. Entry Date: 20180725. Revision Date: 20190113. Publication Type: journal article AU - Chow, Erika T. AU - Otis, John D. AU - Simons, Laura E. DB - cin20 DO - 10.1016/j.jpain.2016.02.014 DP - EBSCOhost IS - 6 KW - Parents -- Psychosocial Factors Stress, Psychological -- Psychosocial Factors Parent-Child Relations Chronic Pain -- Psychosocial Factors Anxiety -- Psychosocial Factors Young Adult Male Prospective Studies Retrospective Design Child Anxiety -- Etiology Depression -- Psychosocial Factors Adolescence Sex Factors Female Fear Child, Disabled -- Psychosocial Factors Disability Evaluation Depression -- Etiology Funding Source N1 - research. Journal Subset: Biomedical; Peer Reviewed; USA. Grant Information: UL1 TR000170/TR/NCATS NIH HHS/United States. NLM UID: 100898657. PMID: NLM26993960. PY - 2016 SN - 1526-5900 SP - 729-738 ST - The Longitudinal Impact of Parent Distress and Behavior on Functional Outcomes Among Youth With Chronic Pain T2 - Journal of Pain TI - The Longitudinal Impact of Parent Distress and Behavior on Functional Outcomes Among Youth With Chronic Pain UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=115742669&site=ehost-live&scope=site VL - 17 ID - 405 ER - TY - JOUR AB - OBJECTIVE: To establish a profile of sports hand injuries requiring treatment in an urban accident and emergency (A&E) department, and to determine the extent to which these injuries resulted in morbidity. METHODS: A one year prospective observational study at the Royal Victoria Infirmary, Newcastle upon Tyne. All patients presenting to the A&E department between 29 July 1995 and 28 July 1996 with a hand injury sustained during sporting activity and who received follow up by A&E or plastic surgery units were enrolled. Patients were contacted by telephone or post at median of four months after injury (range two to 13) for their assessment of the outcome. RESULTS: 262 cases were enrolled into the study. The median age for males was 21 years (range 7 to 55) and for females 16 (range 9 to 40). Follow up data were obtained by telephone in 206 (79%), and by letter in a further 26 (10%). Fractures were the commonest injury (68%), followed by soft tissue injuries (20%) and dislocations (11%). The thumb was the site affected most commonly overall, and in 10 of 17 ski related injuries; next most frequent sites were little and ring fingers. Males sustained 79% of the injuries, and 54% of these occurred during football. Netball/basketball caused 63% of female injuries. Follow up indicated that mild impairment in terms of pain, stiffness, or deformity was common (45%), while the incidence of moderate pain or serious problems was 11%. CONCLUSIONS: Sporting injuries to the hand commonly require treatment in the A&E department. Telephone/postal follow up of such injuries indicates that significant short term and longer term impairment of function may result. Suitable target areas for injury prevention are secondary schools, football (in males), and netball/basketball. AD - Accident and Emergency Department, Middlesbrough General Hospital, Newcastle upon Tyne, UK AN - 107088580. Language: English. Entry Date: 20000201. Revision Date: 20200708. Publication Type: Journal Article AU - Choyce, M. Q. AU - Potts, M. AU - Maitra, A. K. DB - cin20 DO - 10.1136/emj.15.1.35 DP - EBSCOhost IS - 1 KW - Athletic Injuries -- Epidemiology -- United Kingdom Emergency Service Hand Injuries -- Epidemiology -- United Kingdom Athletic Injuries -- Prevention and Control Hand Injuries -- Prevention and Control Male Female Child Adolescence Adult Outcome Assessment Prospective Studies Record Review Questionnaires Telephone Semi-Structured Interview Data Analysis Software Chi Square Test P-Value Age Factors Sex Factors Descriptive Statistics United Kingdom Human N1 - research; tables/charts. Journal Subset: Allied Health; Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. NLM UID: 9433751. PMID: NLM9475221. PY - 1998 SN - 1351-0622 SP - 35-38 ST - A profile of sports hand injuries in an accident and emergency department T2 - Journal of Accident & Emergency Medicine TI - A profile of sports hand injuries in an accident and emergency department UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=107088580&site=ehost-live&scope=site VL - 15 ID - 839 ER - TY - JOUR AB - Chronic Pain without an identifiable organic basis represents a substantial element of referrals to both medical and mental health professionals. Chronic pain can compromise independence, school attendance, physical and social activities. The tendency to label 'nonorganic' pain as having a psychological origin is usually strongly resisted by parents and young people with treatment creating a significant challenge for health care professionals. Collaborative, multidisciplinary treatment programmes encourage families to find ways of getting on with their lives by taking a proactive approach to challenging pain. The family is invited to join with the team in the task of challenging the pain through the use of physiotherapy to increase strength, stamina and suppleness alongside a range of individual and group activities that can include relaxation training, hypnotherapy, systemic and cognitive-behavioural approaches. This article describes how drama and movement therapy was introduced as an additional component of the treatment programme of two adolescents who had been long-term inpatients on a medical adolescent ward. The experiences of adding a complementary therapy to the programme are described to illustrate a creative way of contributing to established treatment programmes through the use of sound, movement and gesture in order to provide a space to explore new ways of being and expanding abilities. Copyright © 2006 SAGE Publications Ltd. AD - University College London and Middlesex Hospitals, UK AN - 106236095. Language: English. Entry Date: 20070216. Revision Date: 20200708. Publication Type: Journal Article AU - Christie, D. AU - Hood, D. AU - Griffin, A. DB - cin20 DO - 10.1177/1359104506067878 DP - EBSCOhost IS - 4 KW - Chronic Pain -- Therapy -- In Adolescence Drama Movement Somatoform Disorders -- Therapy -- In Adolescence Adolescence Female Hypnosis Low Back Pain Neck Pain Occupational Therapy Physical Therapy Psychotherapy Shoulder Pain N1 - case study. Journal Subset: Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. NLM UID: 9604507. PMID: NLM17163225. PY - 2006 SN - 1359-1045 SP - 569-577 ST - Thinking, feeling and moving: drama and movement therapy as an adjunct to a multidisciplinary rehabilitation approach for chronic pain in two adolescent girls T2 - Clinical Child Psychology & Psychiatry TI - Thinking, feeling and moving: drama and movement therapy as an adjunct to a multidisciplinary rehabilitation approach for chronic pain in two adolescent girls UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106236095&site=ehost-live&scope=site VL - 11 ID - 719 ER - TY - JOUR AB - Objectives: The aim of study was to evaluate the trigger points [TrPs] in young university students. Methods: University students from both sexes were randomly evaluated and divided in two groups: students with myofascial pain syndrome [MPS] and without MPS as a control group matched with the MPS subjects' characteristics such as age, body mass, and sex. Average pain, fatigue severity on the visual analog scale [0-10 cm], postural abnormalities, morning stiffness, paresthesia, pain, fatigue, and number of TrPs were evaluated. Results: There were 54 subjects in the MPS group and 60 subjects in the control group. The highest postural misalignment in both groups was found in forward head and pectoral muscle shortening. Control group male and female subjects' general evaluation score, fatigue, and number of TrPs were observed to be statistically lower than MPS group's male and female subjects [P < 0.001]. Four TrPs [M: 33.3 percent, F: 36.7 percent] in MPS subjects and one or no TrPs [M: 66.7 percent, F: 70.0 percent] in control groups subjects were found the highest frequencies. Most of TrPs were observed on the trapezium muscle. General evaluation score and academic achievement were found higher in subjects who suffer from pain six to 11 months than in subjects who suffer from pain zero to five months [P < 0.05]. In addition, general evaluation score and TrPs were observed higher in subjects suffering pain 12 or more months than subjects suffering from pain zero to five months [P < 0.001]. Conclusions: Trigger points that developed during the school years can become chronic and seem to become more symptomatic with time. Further research is required to prevent and successfully manage TrPs that develop in young subjects. AD - Assistant Professor, Dumlupinar University Health Institution of Higher Education, Department of Physical Therapy and Rehabilitation, 43100 Kutahya, Turkey; alicimbiz@yahoo.com AN - 106146187. Language: English. Entry Date: 20070907. Revision Date: 20200624. Publication Type: Journal Article AU - Cimbiz, A. AU - Beydemir, F. AU - Manisaligil, U. DB - cin20 DO - 10.1300/j094v14n04_04 DP - EBSCOhost IS - 4 KW - Students, College Trigger Point -- Diagnosis Academic Achievement Adolescence Adult Biomechanics Body Height Body Weight Comparative Studies Data Analysis Software Descriptive Statistics Fatigue Female Male Matched Case Control P-Value Posture Random Sample T-Tests Trapezius Muscles -- Physiopathology Turkey Visual Analog Scaling Human N1 - questionnaire/scale; research; tables/charts. Journal Subset: Biomedical; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 9302330. PY - 2006 SN - 1058-2452 SP - 27-35 ST - Evaluation of trigger points in young subjects T2 - Journal of Musculoskeletal Pain TI - Evaluation of trigger points in young subjects UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106146187&site=ehost-live&scope=site VL - 14 ID - 716 ER - TY - JOUR AB - Objectives: To explore how adolescents' pain coping profiles relate to their expectations regarding psychological treatment recommendations, and to examine patients' functioning and engagement in psychological treatment three months following a multidisciplinary pain clinic evaluation.Methods: Adolescents and their parents completed measures of pain coping strategies, treatment expectations, pain ratings, somatic symptoms, school absences and functional disability. Parents also reported whether patients followed through with psychological treatment recommendations.Results: Adaptive copers and their parents were more likely to expect psychological treatments to be helpful; however, at follow-up, there were no significant group differences in patients' participation in psychological treatment. Patients in both groups experienced significantly lower levels of somatic symptoms and functional disability, and had fewer school absences from the initial evaluation to the follow-up.Discussion: The results of the present study identify preliminary clinical implications for the way in which practitioners in multidisciplinary pain clinics present recommendations for psychological treatment to patients and their families. AD - Department of Anesthesiology, Perioperative and Pain Medicine, Harvard Medical School, Boston, MA, USA AN - 108242720. Language: English. Entry Date: 20110923. Revision Date: 20200708. Publication Type: journal article AU - Claar, R. L. AU - Simons, L. E. AU - Claar, Robyn Lewis AU - Simons, Laura E. DB - cin20 DO - 10.1155/2011/652853 DP - EBSCOhost IS - 3 KW - Adaptation, Psychological Behavior Therapy -- Methods Pain -- Physiopathology Pain -- Psychosocial Factors Pain -- Therapy Patient Compliance Adolescence Disability Evaluation Female Male Pain Clinics Pain Measurement Parents -- Psychosocial Factors Prospective Studies Retrospective Design Somatosensory Disorders -- Diagnosis Somatosensory Disorders -- Etiology Treatment Outcomes N1 - research. Journal Subset: Biomedical; Canada. NLM UID: 9612504. PMID: NLM21766070. PY - 2011 SN - 1203-6765 SP - 192-196 ST - Adolescents' pain coping profiles: expectations for treatment, functional outcomes and adherence to psychological treatment recommendations T2 - Pain Research & Management TI - Adolescents' pain coping profiles: expectations for treatment, functional outcomes and adherence to psychological treatment recommendations UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=108242720&site=ehost-live&scope=site VL - 16 ID - 584 ER - TY - JOUR AB - Objective: Identifying factors contributing to high medical utilization and productivity loss is important, given the high cost of pediatric chronic pain. The current study examined chronic pain acceptance as a predictor of medical utilization and school absenteeism in adolescents with chronic pain.Methods: In all, 122 adolescents (aged 12-21 years) with chronic pain and their parents/guardians completed questionnaires assessing medical visits (past 6 months), medication usage, and number of school absences (past month). Homebound school status was also reported. Adolescents completed the Chronic Pain Acceptance Questionnaire and pain intensity ratings, and underwent a diagnostic psychological evaluation.Results: Multivariate generalized linear model analyses indicated lower pain acceptance predicted increased inpatient hospitalizations and higher number of opioid and nonopioid prescription medications, controlling for pain intensity, age, and sex. Pain acceptance was not associated with outpatient consultations or number of nonprescription medications. Exploratory moderation analyses indicated lower pain acceptance significantly predicted increased emergency department visits and inpatient hospitalizations for patients diagnosed with an internalizing psychological disorder. Patients in homebound schooling reported low pain acceptance and for those in school full-time, linear regression indicated lower pain acceptance significantly predicted higher number of school absences.Conclusions: Findings suggest that lower pain acceptance contributes to the use of higher-level medical care (especially for adolescents with internalizing disorders) and increased productivity loss owing to school absences or homebound school status. Clinical implications exist for recommending acceptance-based interventions for pain acceptance promotion and continued development of cost-effective, easily disseminated acceptance-based therapy modules to curb the economic burden of chronic pain. AD - Department of Psychology, University of Houston Psychology Section, Baylor College of Medicine Department of Anesthesiology, Baylor College of Medicine AN - 128635751. Language: English. Entry Date: 20190927. Revision Date: 20190927. Publication Type: journal article. Journal Subset: Biomedical AU - Clementi, Michelle A. AU - Kao, Grace S. AU - Monico, Evelyn DB - cin20 DO - 10.1093/jpepsy/jsx125 DP - EBSCOhost IS - 3 KW - Patient Attitudes Absenteeism Adolescent Behavior Chronic Pain -- Psychosocial Factors Schools Child Male Young Adult Female Adolescence Adult Scales N1 - Peer Reviewed; USA. Instrumentation: Productivity Environmental Preference Survey (PEPS); Clinical Decision Making in Nursing Scale (CDMNS) (Jenkins). NLM UID: 7801773. PMID: NLM29048520. PY - 2018 SN - 0146-8693 SP - 294-302 ST - Pain Acceptance as a Predictor of Medical Utilization and School Absenteeism in Adolescents With Chronic Pain T2 - Journal of Pediatric Psychology TI - Pain Acceptance as a Predictor of Medical Utilization and School Absenteeism in Adolescents With Chronic Pain UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=128635751&site=ehost-live&scope=site VL - 43 ID - 310 ER - TY - JOUR AB - A number of adolescents with chronic pain have clinically significant disability across physical, social, and academic activities, and pain severity only explains a portion of the variance in functioning. Thus, it is important to identify therapeutic options to improve adolescents' functioning. In contrast to studies with adults with chronic pain, research in pediatric pain has not consistently found anxiety to be a good predictor of pain-related disability. The present study evaluated pain, anxiety, and functioning in 222 adolescents with chronic pain. Results indicated that pain was consistently and linearly related to disability across measures of physical and social functioning, school attendance, and physician visits. The relation between anxiety and functioning was complex; increased anxiety was related to poorer physical and social functioning and was related to fewer physician visits, although it was not associated with school attendance. Additional analyses revealed that anxiety serves to moderate the relation between pain and functioning. Specifically, at high anxiety, pain was not related to functioning, but at low anxiety, pain consistently predicted disability. In other words, highly anxious adolescents were functioning poorly regardless of the level of pain. The moderating role of anxiety highlights a number of research and clinical possibilities to explore with adolescents with chronic pain-related disability. PERSPECTIVE: Data suggest that high anxiety is associated with poor functioning irrespective of pain intensity. At low anxiety, higher pain predicted greater disability. Anxiety is important to assess when investigating potential reasons for pain-related disability. AD - Department of Psychology, Georgia State University, Atlanta, Georgia; Centre for Pain Research, School for Health, University of Bath, Bath, UK. AN - 104940652. Language: English. Entry Date: 20111007. Revision Date: 20150711. Publication Type: Journal Article. Journal Subset: Biomedical AU - Cohen, L. L. AU - Vowles, K. E. AU - Eccleston, C. DB - cin20 DO - 10.1016/j.jpain.2009.09.009 DP - EBSCOhost IS - 11 KW - Activities of Daily Living -- Psychosocial Factors Anxiety Disorders -- Epidemiology Anxiety Disorders -- Psychosocial Factors Child, Disabled -- Psychosocial Factors Pain -- Epidemiology Pain -- Psychosocial Factors Adolescence Child Chronic Disease Comorbidity Female Male N1 - Peer Reviewed; USA. NLM UID: 100898657. PMID: NLM20015706. PY - 2010 SN - 1526-5900 SP - 1039-1046 ST - The impact of adolescent chronic pain on functioning: disentangling the complex role of anxiety T2 - Journal of Pain TI - The impact of adolescent chronic pain on functioning: disentangling the complex role of anxiety UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104940652&site=ehost-live&scope=site VL - 11 ID - 608 ER - TY - JOUR AB - The amount of time missed from school in two small town school populations was estimated by measuring absence from school and attendance at sickbay, and stated causes were analysed. School absence related to headache (expressed as percentage of pupil days missed out of possible pupil days, during two 12 week periods) in children aged 5 to 14 years, was 0.05%. This represented approximately 1% of all school absence, and was recorded (usually only once) in 3.7% of children. The duration of absence was one day or less on 85% of occasions. This low absence rate was in contrast with the high prevalence of headache reported by children aged 9 to 14 of between 76 and 94% according to age and sex. Attendance at school sick bay because of headache was recorded in 3.6% of children aged 5 to 19 (only 0.5% then left school early because of headache) in one 12 week period. It is concluded that although headache prevalence is high in the age groups studied, it is not a prominent cause of time missed from school. AN - 66682153. Language: English. Entry Date: 20190505. Revision Date: 20190505. Publication Type: journal article AU - Collin, C. AU - Hockaday, J. M. AU - Waters, W. E. DB - cin20 DP - EBSCOhost IS - 3 KW - Students Absenteeism Headache -- Epidemiology England Child, Preschool Human Prospective Studies Child Female Adolescence Male Validation Studies Comparative Studies Evaluation Research Multicenter Studies N1 - research. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 0372434. PMID: NLM3985656. PY - 1985 SN - 0003-9888 SP - 245-247 ST - Headache and school absence T2 - Archives of Disease in Childhood TI - Headache and school absence UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=66682153&site=ehost-live&scope=site VL - 60 ID - 860 ER - TY - JOUR AB - * SYNOPSIS: One of the key aspects of good health care for children and young people is the prevention and management of pain. The experience of persistent pain in children and adolescents not only has a major impact on physical, emotional, social, and developmental well-being, but also impacts the broader world, which includes family, school, and social networks. The multidisciplinary pediatric pain clinic adopts a holistic approach to care through a biopsychosocial model. One outcome of an initial pediatric pain clinic review is the creation of a pain management plan that addresses the pharmacological, physical, psychological, and other domains of care. Pediatric pain clinics are improving access by embracing technology through tele-health and internet-based treatment options. Outcome measurement will guide the development of models of care in the future. AD - Department of Pain Medicine, The Children's Hospital at Westmead, Westmead, Australia AN - 125905048. Language: English. Entry Date: 20171103. Revision Date: 20180101. Publication Type: Article AU - Collins, John AU - Haynes, Natasha AU - Klingberg, Hannah AU - Nicholas, Heather AU - Pounder, M. E. G. AU - Sandells, Renee DB - cin20 DO - 10.2519/jospt.2017.7355 DP - EBSCOhost IS - 10 KW - Chronic Pain -- Therapy -- In Infancy and Childhood Chronic Pain -- Therapy -- In Adolescence Pain Clinics Health Care Delivery -- Methods -- In Infancy and Childhood Health Care Delivery -- Methods -- In Adolescence Patient Care -- Methods Multidisciplinary Care Team Patient Assessment Australia Professional Role Nurse Practitioners Physical Therapists Psychologists Physicians Outcome Assessment -- Methods Chronic Pain -- Epidemiology -- In Infancy and Childhood Chronic Pain -- Epidemiology -- In Adolescence Chronic Pain -- Physiopathology -- In Infancy and Childhood Chronic Pain -- Physiopathology -- In Adolescence Chronic Pain -- Psychosocial Factors -- In Infancy and Childhood Chronic Pain -- Psychosocial Factors -- In Adolescence Child Adolescence N1 - tables/charts. Journal Subset: Allied Health; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Pain and Pain Management; Pediatric Care. NLM UID: 7908150. PY - 2017 SN - 0190-6011 SP - 806-813 ST - The Management of Complex Pain in Children Referred to a Pain Clinic at a Tertiary Childrens Hospital in Australia T2 - Journal of Orthopaedic & Sports Physical Therapy T3 - Musculoskeletal Conditions in Children TI - The Management of Complex Pain in Children Referred to a Pain Clinic at a Tertiary Childrens Hospital in Australia UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=125905048&site=ehost-live&scope=site VL - 47 ID - 343 ER - TY - JOUR AB - The present study used electronic diaries to examine how parent responses to their child's pain predict daily adjustment of children with juvenile idiopathic arthritis (JIA). Nine school-aged children with JIA along with one of their parents completed thrice-daily assessments of pain-related variables, activity participation, and mood using handheld computers (Palm pilots) for 14 days, yielding a potential of 42 child and parent assessments for each dyad. Children provided information on current pain level, mood, and participation in social, physical, and school activities. Parents independently rated their own mood as well as their behavioral responses to their child's pain at the same time points using a separate handheld computer. Results of multilevel modeling analyses demonstrated that use of "protective" pain responses by parents significantly predicted decreases in child activity and positive mood, with an even stronger inverse relationship between protective pain response and positive mood observed in children with higher than average disease severity. Protective pain responses were not found to be significantly predictive of daily negative mood in children. The use of "distracting" responses by parents significantly predicted less child activity restrictions but only in children having higher disease severity. There also was an unexpected trend in which parent use of more distracting pain responses tended to be associated with lower child positive mood. These preliminary findings suggest the importance of the parent in influencing adjustment in children with JIA and lend support to the incorporation of parents into comprehensive pain management approaches. The potential benefits of using electronic daily diaries as a strategy to examine pain and adjustment in children with JIA pain are discussed. AD - Children's Mercy Hospitals and Clinics, Kansas City, Missouri 64108, USA Children's Mercy Hospitals and Clinics, Kansas City, Missouri 64108, USA. mconnelly1@cmh.edu AN - 105154332. Language: English. Entry Date: 20100702. Revision Date: 20200708. Publication Type: journal article AU - Connelly, M. AU - Anthony, K. K. AU - Sarniak, R. AU - Bromberg, M. H. AU - Gil, K. M. AU - Schanberg, L. E. AU - Connelly, Mark AU - Anthony, Kelly K. AU - Sarniak, Rebecca AU - Bromberg, Maggie H. AU - Gil, Karen M. AU - Schanberg, Laura E. DB - cin20 DO - 10.1016/j.jpainsymman.2009.07.013 DP - EBSCOhost IS - 3 KW - Activities of Daily Living Affect Arthritis, Juvenile Rheumatoid -- Psychosocial Factors Medical Records Pain -- Psychosocial Factors Parents -- Psychosocial Factors Adaptation, Psychological Adolescence Adult Caregivers Child Female Human Male Predictive Value of Tests Prognosis Social Behavior N1 - research. Journal Subset: Biomedical; Core Nursing; Nursing; Peer Reviewed; USA. Grant Information: R55 AR045238/AR/NIAMS NIH HHS/United States. NLM UID: 8605836. PMID: NLM20303032. PY - 2010 SN - 0885-3924 SP - 579-590 ST - Parent pain responses as predictors of daily activities and mood in children with juvenile idiopathic arthritis: the utility of electronic diaries T2 - Journal of Pain & Symptom Management TI - Parent pain responses as predictors of daily activities and mood in children with juvenile idiopathic arthritis: the utility of electronic diaries UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105154332&site=ehost-live&scope=site VL - 39 ID - 632 ER - TY - JOUR AB - Migraine is a common health problem in youth that is ranked highest for disability among neurological conditions and is one of the leading reasons for school absences. Children with migraines frequently are seen by the school nurse for care, sometimes before ever being seen by another healthcare provider for evaluation and treatment. As such, school nurses have the unique opportunity to provide education and resources to children with migraines and their family. This article provides information on the Headache Action Plan Program for Youth (HAPPY), a project involving the provision of live and online migraine education and management resources to school nurses, children, families, and primary care providers in an effort to improve migraine recognition and care in the community. AD - Professor of Pediatrics, Kansas City, MO Medical Director and Chief of the Headache Section in Neurology, Kansas City, MO Advanced Practice Nurse, Kansas City, MO Health Services Consultant, Olathe, KS AN - 126841251. Language: English. Entry Date: 20180102. Revision Date: 20191107. Publication Type: Article AU - Connelly, Mark AU - Bickel, Jennifer AU - Wingert, Tammie AU - Galemore, Cynthia DB - cin20 DO - 10.1177/1942602X17719300 DP - EBSCOhost IS - 1 KW - Migraine -- Prevention and Control Program Implementation Migraine -- Education School Health Nursing Nursing Role Pediatric Care Migraine -- Diagnosis Migraine -- Therapy Family -- Education Students Child Physicians, Family -- Education Nurses -- Education Health Education Teaching Methods Internet Outcomes (Health Care) Quality of Life Migraine -- Nursing N1 - pictorial; tables/charts. Journal Subset: Editorial Board Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Pediatric Care. PY - 2018 SN - 1942-602X SP - 40-47 ST - The Headache Action Plan Project for Youth (HAPPY): School Nurses as Facilitators of System Change in Pediatric Migraine Care T2 - NASN School Nurse TI - The Headache Action Plan Project for Youth (HAPPY): School Nurses as Facilitators of System Change in Pediatric Migraine Care UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=126841251&site=ehost-live&scope=site VL - 33 ID - 329 ER - TY - JOUR AB - Background: Associations between the quality of nursing care and patient outcomes have been demonstrated globally. However, translation and application of this evidence to robust measurement in pediatric specialty nursing care has been limited. Objectives: To test the feasibility and performance of nurse-sensitive measures in pediatric cardiovascular programs. Methods: Ten nurse-sensitive measures targeting nursing workforce, care process, and patient outcomes were implemented, and measurement data were collected for 6 months across 9 children's hospitals in the Consortium of Congenital Cardiac Care–Measurement of Nursing Practice (C4-MNP). Participating sites evaluated the feasibility of collecting data and the usability of the data. Results: Variations in nursing workforce characteristics were reported across sites, including proportion of registered nurses with 0 to 2 years of experience, nursing education, and nursing certification. Clinical measurement data on weight gain in infants who have undergone cardiac surgery, unplanned transfer to the cardiac intensive care unit, and pain management highlighted opportunities for improvement in care processes. Overall, each measure received a score of 75% or greater in feasibility and usability. Conclusions: Collaborative evaluation of measurement performance, feasibility, and usability provided important information for continued refinement of the measures, development of systems to support data collection, and selection of benchmarks across C4-MNP. Results supported the development of target benchmarks for C4-MNP sites to compare performance, share best practices for improving the quality of pediatric cardiovascular nursing care, and inform nurse staffing models. AD - Jean Connor is director of nursing research, Cardiovascular and Critical Care Services, Department of Nursing Patient Services, Boston Children's Hospital, and an assistant professor of pediatrics, Harvard Medical School, Boston, Massachusetts. Lauren Hartwell is project manager III, Population Health, Tufts Health Plan, Watertown, Massachusetts. Jennifer Baird is director, Institute for Nursing and Interprofessional Research, Children's Hospital Los Angeles, California. Benjamin Cerrato is project coordinator, Cardiovascular and Critical Care Services, Boston Children's Hospital. Araz Chiloyan is a quality improvement consultant, Department of Cardiology, Boston Children's Hospital. Courtney Porter is program manager, Center for Healthy Adolescent Transition, Children's Hospital Los Angeles. Patricia Hickey is vice president, Cardiovascular and Critical Care Services, associate chief nursing officer, Department of Nursing Patient Services, Boston Children's Hospital, and an assistant professor of pediatrics, Harvard Medical School. AN - 146653059. Language: English. Entry Date: 20201106. Revision Date: 20210311. Publication Type: Article AU - Connor, Jean AU - Hartwell, Lauren AU - Baird, Jennifer AU - Cerrato, Benjamin AU - Chiloyan, Araz AU - Porter, Courtney AU - Hickey, Patricia DB - cin20 DO - 10.4037/ajcc2020884 DP - EBSCOhost IS - 6 KW - Clinical Indicators Benchmarking Cardiovascular Nursing Registered Nurses Pediatric Cardiology Program Evaluation Ambulatory Care Facilities -- United States Human Workforce Nursing Staff, Hospital United States Nursing Role Job Performance Competency Assessment Collaboration Clinical Competence Quality of Nursing Care Quality Improvement Funding Source N1 - research; tables/charts. Journal Subset: Blind Peer Reviewed; Core Nursing; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Grant Information: This work was funded by the Congenital Heart Disease Coalition, American Association of Critical-Care Nurses Research Impact Award, and Boston Children’s Hospital Program for Patient Safety and Quality Grant.. NLM UID: 9211547. PY - 2020 SN - 1062-3264 SP - 468-478 ST - Nurse-Sensitive Quality Metrics to Benchmark in Pediatric Cardiovascular Care T2 - American Journal of Critical Care TI - Nurse-Sensitive Quality Metrics to Benchmark in Pediatric Cardiovascular Care UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=146653059&site=ehost-live&scope=site VL - 29 ID - 160 ER - TY - JOUR AB - Objective: The use of acupuncture in the United States has consistently grown over the last two decades, and the National Center for Complementary and Integrative Health has recently called for greater understanding of 'real life outcomes and use' by complementary and alternative medicine users. This study assesses the demographics and utilization patterns of 'super-users' treated at the Oregon College of Oriental Medicine intern clinic. Methods: This was a retrospective chart review at the Oregon College of Oriental Medicine (OCOM) intern clinic, a large acupuncture and oriental medicine (AOM) school in Portland, Oregon. Participants were patients who were treated 100+ times at the OCOM between August 6, 2002, and 2012. The outcome measures were demographic and treatment characteristics, including sex, age, chief complaint, income, medication use, and visit patterns. Results: The super-user cohort comprised approximately 1.5% of the total annual patient population and 8% of total visits at the OCOM in any given year, with an average treatment duration of 4 years from visit 1 to visit 100, and a visit frequency of 32 visits per year. Similar to other studies, the super-user cohort consisted predominantly of older, female patients seeking treatment primarily for pain (57.3%). Prescription medication use (45.2%) was also similar to other acupuncture cohorts. In contrast to typical AOM patients, OCOM super-users were older, with 64% being age ≥50 years when initiating treatment, and a majority reported low-income status (92%). Conclusions: Super-users represent a small yet real subset of AOM patients. They tend to be older, report lower income, and exhibit greater visit frequency than more typical AOM users. The factors motivating AOM super-user behavior may be different from those in other medical domains, notably emergency medicine, and likely include long-term management of chronic pain and other chronic conditions. Future studies into the long-term health outcomes of AOM super-users, as well as the economic impact on other health services, are warranted. AN - 121839217. Language: English. Entry Date: 20170320. Revision Date: 20180301. Publication Type: Article AU - Cooper, Forrest AU - Marx, Benjamin L. AU - Lee, Tamsin L. AU - Espesete, Deborah DB - cin20 DO - 10.1089/acm.2016.0419 DP - EBSCOhost IS - 3 KW - Acupuncture -- Utilization Medicine, East Asian Traditional Demography Socioeconomic Factors Patients -- Psychosocial Factors Human Female Alternative Therapies Chronic Disease Pain Income Oregon Retrospective Design Record Review Schools, Health Occupations Ambulatory Care Facilities Prospective Studies Male Adolescence Young Adult Adult Middle Age Aged, 80 and Over N1 - research; tables/charts. Journal Subset: Alternative/Complementary Therapies; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 9508124. PY - 2017 SN - 1075-5535 SP - 222-226 ST - Super-Users at an Acupuncture and Oriental Medicine Teaching Clinic: Demographics and Unique Clinical Characteristics T2 - Journal of Alternative & Complementary Medicine TI - Super-Users at an Acupuncture and Oriental Medicine Teaching Clinic: Demographics and Unique Clinical Characteristics UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=121839217&site=ehost-live&scope=site VL - 23 ID - 369 ER - TY - JOUR AB - Stickler syndrome is a group of rare genetic conditions (incidence, 1/7500 births) related to mutations in the collagen genes. Both the mutations and the clinical features vary widely across affected patients. The main manifestations are craniofacial birth defects, bone and joint symptoms, ocular abnormalities, and hearing loss. Stickler syndrome may be revealed at birth (25% of cases) by a combination of cleft palate, retrognathism, and micrognathism known as Pierre Robin sequence, which may cause neonatal respiratory problems. The ocular abnormalities include severe myopia, abnormalities of the vitreous, and a high risk of retinal detachment (60% of cases), which may cause blindness (4% of cases). Severe hearing loss with onset in early childhood may impair performance at school. Osteoarthritis (75% of patients) with onset before 30 years of age is a severe manifestation that causes chronic hip and low back pain and functional impairments. Joint replacement surgery is often required. The risk associated with multiple anesthesias is highest in patients with craniofacial defects. The bone status may deserve to be evaluated, as the combination of genetic abnormalities and physical impairments may promote bone loss. Clinicians should be cognizant of Stickler syndrome so that they can detect the disease in patients and their family members, prevent functional impairments, organize a multidisciplinary management strategy, and arrange for genetic counseling. AD - Service de rhumatologie, centre hospitalier de Cholet, 1, rue de Marengo, 49300 Cholet, France Service de rhumatologie, centre hospitalier de Cholet, 1, rue de Marengo, 49300 Cholet, France. AN - 104988562. Language: English. Entry Date: 20110520. Revision Date: 20200708. Publication Type: journal article AU - Couchouron, T. AU - Masson, C. AU - Couchouron, Tifenn AU - Masson, Charles DB - cin20 DO - 10.1016/j.jbspin.2010.03.012 DP - EBSCOhost IS - 1 KW - Osteoarthritis -- Epidemiology Pierre Robin Syndrome -- Epidemiology Age of Onset Arthritis Arthritis -- Epidemiology Arthritis -- Radiography Hearing Loss, Sensorineural Hearing Loss, Sensorineural -- Epidemiology Hearing Loss, Sensorineural -- Radiography Incidence Osteoarthritis Osteoarthritis -- Radiography Pierre Robin Syndrome Pierre Robin Syndrome -- Radiography Retinal Detachment Retinal Detachment -- Epidemiology Retinal Detachment -- Radiography Risk Factors Stickler Syndrome -- Epidemiology Stickler Syndrome -- Radiography N1 - review. Journal Subset: Biomedical; Continental Europe; Europe; Peer Reviewed. NLM UID: 100938016. PMID: NLM20462780. PY - 2011 SN - 1297-319X SP - 45-49 ST - Early-onset progressive osteoarthritis with hereditary progressive ophtalmopathy or Stickler syndrome T2 - Joint Bone Spine TI - Early-onset progressive osteoarthritis with hereditary progressive ophtalmopathy or Stickler syndrome UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104988562&site=ehost-live&scope=site VL - 78 ID - 597 ER - TY - JOUR AB - Meares-Irlen syndrome can be defined as the inability to see comfortably due to visual perceptual distortions. The condition is also known as visual stress or scotopic sensitivity syndrome. The condition is difficult to diagnose as the child or young person is often unaware of it. However, it can have serious consequences on educational achievement and it is crucial that educationalists and school nurses are aware of the symptoms. AD - School Nursing, Leeds Metropolitan University, Leeds, U. K. AN - 61778835. Language: English. Entry Date: 20110715. Revision Date: 20190514. Publication Type: Article AU - Crabtree, Elaine DB - cin20 DO - 10.12968/bjsn.2011.6.4.182 DP - EBSCOhost IS - 4 KW - Vision Disorders -- In Infancy and Childhood Visual Perception Vision Disorders -- Symptoms Reading Disorders -- Etiology Vision Disorders -- Diagnosis Diagnostic Reasoning Color Therapy Professional Practice, Evidence-Based Dyslexia Comorbidity Migraine Epilepsy Academic Performance Child N1 - pictorial. Journal Subset: Europe; Nursing; Peer Reviewed; UK & Ireland. NLM UID: 101297722. PY - 2011 SN - 1752-2803 SP - 182-187 ST - Educational implications of Meares-Irlen syndrome T2 - British Journal of School Nursing TI - Educational implications of Meares-Irlen syndrome UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=61778835&site=ehost-live&scope=site VL - 6 ID - 582 ER - TY - JOUR AB - OBJECTIVES: Recurrent abdominal pain (RAP) affects up to 15% of children. A biopsychosocial approach to the treatment of children with RAP has been proposed as an alternative to the traditional medical model. The aim of this study was to examine whether the parental conceptual model of illness is a factor in the long-term outcome of children with severe RAP. METHODS: The study was undertaken in 2 parts: 1) a review of the medical and psychiatric records (including Child Behavior Checklist [CBCL]) of all children with RAP of sufficient severity to necessitate hospitalization during a 5-year period and 2) a structured telephone interview to collect information on ongoing abdominal pain, other somatic symptoms, school attendance, and the parents' opinion as to the cause of the child's pain. RESULTS: Twenty-eight of 30 children who were identified were available for follow-up. Twenty-three (82%) were tertiary referrals from other pediatric services, and 20 had pain for >6 months. On admission 7 (25%) of 28 had a depressive disorder, and 8 (29%) had an anxiety/depressive disorder. Twenty-one of 28 parents completed the CBCL, and on analysis of the CBCL, 11 (52%) children had scores in the clinical range (>65). At follow-up (mean: 3.56 years; standard deviation: 1.59), 14 (50%) of 28 continued to complain of pain. These children also complained of multiple other somatic complaints and had repeated school absences. Only 1 (7%) of 14 parents of children with ongoing pain believed that there was a psychological cause for their child's pain, whereas 11 (78%) of 14 parents of the children who had recovered believed that the cause was attributable to psychological factors (odds ratio: 47.67; 95% confidence interval: 3.56-1511.6). CONCLUSIONS: The acceptance by parents of a biopsychosocial model of illness is important for the resolution of recurrent abdominal pain in children. AD - Department of Paediatrics, Conway Institute for Biomolecular and Biomedical Research, University College, Dublin, Ireland AN - 106525707. Language: English. Entry Date: 20051014. Revision Date: 20200708. Publication Type: Journal Article AU - Crushell, E. AU - Rowland, M. AU - Doherty, M. AU - Gormally, S. AU - Harty, S. AU - Bourke, B. AU - Drumm, B. DB - cin20 DO - 10.1542/peds.112.6.1368 DP - EBSCOhost IS - 6 KW - Abdominal Pain -- Etiology -- In Infancy and Childhood Abdominal Pain -- Physiopathology -- In Infancy and Childhood Abdominal Pain -- Psychosocial Factors -- In Infancy and Childhood Abdominal Pain -- Therapy -- In Infancy and Childhood Models, Psychological Parents -- Psychosocial Factors Psychophysiologic Disorders -- Diagnosis -- In Infancy and Childhood Psychophysiologic Disorders -- Physiopathology -- In Infancy and Childhood Psychophysiologic Disorders -- Psychosocial Factors -- In Infancy and Childhood Behavior Rating Scales Child Child Behavior Checklist Child Psychiatry Child, Hospitalized Child, Preschool Confidence Intervals Female Funding Source Infant Interviews Male Odds Ratio Prospective Studies Questionnaires Record Review Recurrence Stress, Psychological -- In Infancy and Childhood Human N1 - research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Instrumentation: Child Behavior Checklist (CBCL) (Achenbach and Edelbrock). Grant Information: Children's Medical and Research Foundation, Our Lady's Hospital for Sick Children, Crumlin, Dublin. NLM UID: 0376422. PMID: NLM14654611. PY - 2003 SN - 0031-4005 SP - 1368-1372 ST - Importance of parental conceptual model of illness in severe recurrent abdominal pain T2 - Pediatrics TI - Importance of parental conceptual model of illness in severe recurrent abdominal pain UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106525707&site=ehost-live&scope=site VL - 112 ID - 775 ER - TY - JOUR AB - Background: Functional abdominal pain (FAP) is associated with significant anxiety and impairment. Prior investigations of child anxiety in youth with FAP are generally limited by small sample sizes, based on child report, and use lengthy diagnostic tools. It is unknown whether a brief anxiety-screening tool is feasible, whether parent and child reports of anxiety are congruent, and whether parent and child agreement of child anxiety corresponds to increased impairment. The purpose of this investigation was to examine anxiety characteristics in youth with FAP using parent and child reports. Parent-child agreement of child anxiety symptoms was examined in relation to pain and disability.Methods: One hundred patients with FAP (8-18 years of age) recruited from pediatric gastroenterology clinics completed measures of pain intensity (Numeric Rating Scale) and disability (Functional Disability Inventory). Patients and caregivers both completed a measure of child anxiety characteristics (Screen for Child Anxiety and Related Disorders).Results: Clinically significant anxiety symptoms were more commonly reported by youth (54%) than their parents (30%). Panic/somatic symptoms, generalized anxiety, and separation anxiety were most commonly endorsed by patients, whereas generalized anxiety, separation anxiety, and school avoidance were most commonly reported by parents. The majority (65%) of parents and children agreed on the presence (26%) or absence (39%) of clinically significant anxiety. Parent-child agreement of clinically significant anxiety was related to increased impairment.Conclusions: A brief screening instrument of parent and child reports of anxiety can provide clinically relevant information for comprehensive treatment planning in children with FAP. AN - 109704509. Language: English. Entry Date: 20150605. Revision Date: 20200708. Publication Type: journal article AU - Cunningham, Natoshia R. AU - Cohen, Mitchell B. AU - Farrell, Michael K. AU - Mezoff, Adam G. AU - Lynch-Jordan, Anne AU - Kashikar-Zuck, Susmita DB - cin20 DO - 10.1097/MPG.0000000000000625 DP - EBSCOhost IS - 3 N1 - research. Journal Subset: Allied Health; USA. Grant Information: K24 AR056687/AR/NIAMS NIH HHS/United States. NLM UID: 8211545. PMID: NLM25714575. PY - 2015 SN - 0277-2116 SP - 312-317 ST - Concordant parent-child reports of anxiety predict impairment in youth with functional abdominal pain T2 - Journal of Pediatric Gastroenterology & Nutrition TI - Concordant parent-child reports of anxiety predict impairment in youth with functional abdominal pain UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=109704509&site=ehost-live&scope=site VL - 60 ID - 459 ER - TY - JOUR AB - Objective: The purpose of this case report is to describe the chiropractic care of a 10-year-old boy who presented with developmental delay syndromes, asthma, and chronic neck and head pain and to present an overview of his muscular imbalances during manual muscle testing evaluation that guided the interventions offered to this child. Clinical Features: The child was a poor reader, suffered eye strain while reading, had poor memory for classroom material, and was unable to move easily from one line of text to another during reading. He was using 4 medications for the asthma but was still symptomatic during exercise. Intervention and Outcome: Chiropractic care, using applied kinesiology, guided evaluation, and treatment. Following spinal and cranial treatment, the patient showed improvement in his reading ability, head and neck pain, and respiratory distress. His ability to read improved (in 3 weeks, after 5 treatments), performing at his own grade level. He has remained symptom free for 2 years. Conclusion: The care provided to this patient seemed to help resolve his chronic musculoskeletal dysfunction and pain and improve his academic performance. AD - Chiropractic Health Center, PC, Pueblo, CO; cranialdc@hotmail.com AN - 105101601. Language: English. Entry Date: 20101022. Revision Date: 20150820. Publication Type: Journal Article AU - Cuthbert, S. AU - Rosner, A. DB - cin20 DO - 10.1016/j.jcm.2010.05.002 DP - EBSCOhost IS - 3 KW - Asthma -- Therapy -- In Infancy and Childhood Chiropractic Headache -- Therapy -- In Infancy and Childhood Kinesiology Neck Pain -- Therapy -- In Infancy and Childhood Reading Disorders -- Therapy -- In Infancy and Childhood Child Male Physical Examination Reading N1 - case study; pictorial. Journal Subset: Alternative/Complementary Therapies; Blind Peer Reviewed; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. PY - 2010 SN - 1556-3707 SP - 138-145 ST - Applied kinesiology methods for a 10-year-old child with headaches, neck pain, asthma, and reading disabilities T2 - Journal of Chiropractic Medicine TI - Applied kinesiology methods for a 10-year-old child with headaches, neck pain, asthma, and reading disabilities UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105101601&site=ehost-live&scope=site VL - 9 ID - 613 ER - TY - JOUR AB - Objectives: A significant proportion of children with functional abdominal pain develop chronic pain. Identifying clinical characteristics predicting pain persistence is important in targeting interventions. We examined whether child anxiety and/or pain-stooling relations were related to maintenance of abdominal pain frequency and compared the predictive value of 3 methods for assessing pain-stooling relations (ie, diary, parent report, child report).Methods: Seventy-six children (7-10 years old at baseline) who presented for medical treatment of functional abdominal pain were followed up 18 to 24 months later. Baseline anxiety and abdominal pain-stooling relations based on pain and stooling diaries and child- and parent questionnaires were examined in relationship to the persistence of abdominal pain frequency.Results: Children's baseline anxiety was not related to persistence of pain frequency. Children who, however, displayed irritable bowel syndrome (IBS) symptoms at baseline maintained pain frequency at follow-up, whereas in children in whom there was no relationship between pain and stooling, pain frequency decreased. Pain and stool diaries and parent report of pain-stooling relations were predictive of pain persistence but child-report questionnaires were not.Conclusions: The presence of IBS symptoms in school-age children with functional abdominal pain appears to predict persistence of abdominal pain over time, whereas anxiety does not. Prospective pain and stooling diaries and parent report of IBS symptoms were predictors of pain maintenance, but child report of symptoms was not. AD - Department of Pediatrics, Baylor College of Medicine, Houston, Texas Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, Texas Texas Children's Hospital, Houston, Texas Indiana University School of Medicine & Riley Child and Adolescent Psychiatry Clinic, Indianapolis Children's Nutrition Research Center, Houston, Texas George Washington School of Medicine and Health Sciences, Washington, DC AN - 113453887. Language: English. Entry Date: 20160625. Revision Date: 20190619. Publication Type: journal article AU - Czyzewski, Danita I. AU - Self, Mariella M. AU - Williams, Amy E. AU - Weidler, Erica M. AU - Blatz, Allison M. AU - Shulman, Robert J. DB - cin20 DO - 10.1097/MPG.0000000000000947 DP - EBSCOhost IS - 3 KW - Abdominal Pain -- Diagnosis Irritable Bowel Syndrome -- Diagnosis Child Human Female Defecation Prospective Studies Pain Measurement -- Methods Irritable Bowel Syndrome -- Psychosocial Factors Anxiety Disorders -- Diagnosis Male Abdominal Pain -- Psychosocial Factors Validation Studies Comparative Studies Evaluation Research Multicenter Studies Funding Source N1 - research. Journal Subset: Allied Health; USA. Grant Information: P30 DK56338/DK/NIDDK NIH HHS/United States. NLM UID: 8211545. PMID: NLM26301615. PY - 2016 SN - 0277-2116 SP - 393-398 ST - Maintenance of Pain in Children With Functional Abdominal Pain T2 - Journal of Pediatric Gastroenterology & Nutrition TI - Maintenance of Pain in Children With Functional Abdominal Pain UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=113453887&site=ehost-live&scope=site VL - 62 ID - 419 ER - TY - JOUR AB - OBJECTIVES: To determine the suitability of the Migraine Disability Assessment (MIDAS) Questionnaire for assessing disability in children and adolescents with headache and to obtain preliminary information about disability in different primary headaches. BACKGROUND: During the last decade, researchers have begun to employ standardized methodologies to investigate the global impact of primary headaches. Disease-specific instruments have been developed to measure headache-related disability. The MIDAS Questionnaire, which is the most extensively studied of these instruments, was designed to assess the overall impact of headaches over the 3 months before compilation. The MIDAS Questionnaire is an optimal tool to assess headache-related disability in adults. METHODS: Ninety-five patients aged 7 to 17 years with tension-type headache, migraine, or both completed the validated Italian form of the MIDAS questionnaire on 2 occasions. Test-retest reliability was assessed by the Spearman rank correlation test. The Cronbach alpha assessed internal consistency. The patients answered questions about the adequacy of the questionnaire. RESULTS: The Cronbach alpha was.8. Correlation coefficients were generally high for the overall MIDAS score and for the items investigating disability in school and in family/leisure activities; they were lower for the items about housework. Most patients thought that the MIDAS Questionnaire was useful (98.9%) and that it captured the impact of their headaches (58.9%); 41% thought that questions about disability in housework were useless, 44.2% suggested adding questions regarding inability to do homework. All primary headaches had a considerable impact on daily activities, but patients with migraine tended to have lower headache frequencies and lower total disability time; those with tension-type headache suffered more days in which activities, although performed, were substantially impaired. CONCLUSIONS: The MIDAS Questionnaire is useful for assessing disability in children and adolescents with different primary headaches. Minimal changes in the phrasing and content of the items would be sufficient to render the MIDAS specific for the younger population with headache. AD - Headache Center, C Besta National Neurological Institute, Via Celoria, 11, 20133 Milan, Italy AN - 106768541. Language: English. Entry Date: 20081219. Revision Date: 20200708. Publication Type: Journal Article AU - D'Amico, D. AU - Grazzi, L. AU - Usai, S. AU - Andrasik, F. AU - Leone, M. AU - Rigamonti, A. AU - Bussone, G. DB - cin20 DO - 10.1046/j.1526-4610.2003.03134.x DP - EBSCOhost IS - 7 KW - Headache -- Diagnosis -- In Infancy and Childhood Instrument Validation Adolescence Child Coefficient Alpha Descriptive Statistics Female Internal Consistency Italy Male P-Value Research Instruments Spearman's Rank Correlation Coefficient Test-Retest Reliability Validation Studies Human N1 - research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. Instrumentation: Migraine Disability Assessment Score (MIDAS) Questionnaire. NLM UID: 2985091R. PMID: NLM12890131. PY - 2003 SN - 0017-8748 SP - 767-773 ST - Use of the Migraine Disability Assessment Questionnaire in children and adolescents with headache: an Italian pilot study T2 - Headache: The Journal of Head & Face Pain TI - Use of the Migraine Disability Assessment Questionnaire in children and adolescents with headache: an Italian pilot study UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106768541&site=ehost-live&scope=site VL - 43 ID - 784 ER - TY - JOUR AB - Background: Pediatric health-related quality of life (HRQOL) questionnaires have been validated in children with sickle cell disease (SCD), but small sample sizes in these studies have limited clinical comparisons. We used the baseline clinical data from the Collaborative Data (C-Data) Project of the Comprehensive Sickle Cell Centers (CSCC) Clinical Trial Consortium to perform a detailed, descriptive study of HRQOL using the PedsQL version 4.0 generic core and fatigue scales.Methods: Retrospective clinical data were obtained via medical record abstraction. Staff-administered health history, psychosocial, and health behavior interviews were completed by a parent or guardian. PedsQL forms were completed separately by the child and a parent/guardian.Results: The study enrolled 1,772 subjects (53% boys) with a mean age of 9.6 years (SD 4.7). SS or Sbeta(0) thalassemia occurred in 68% and 32% had SC or Sbeta(+) thalassemia. The occurrences of pain, priapism, avascular necrosis of hips/shoulders (AVN), or asthma were the most common complications/conditions reported. Multiple regression models controlling for hemoglobinopathies, gender, and age suggested that parent reports of physical functioning and sleep/rest fatigue declined in response to pain or AVN, while school functioning scales declined in response to pain or asthma. Sickle pain, and to a lesser extent asthma, negatively influenced child reports on almost all functioning and fatigue scales.Conclusions: While longitudinal studies will be necessary to determine sensitivity to change, the current study suggests the potential utility of several PedsQL HRQOL scales as patient-reported outcome measures for observational or interventional treatment studies of children and adolescents with SCD. AD - Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia. AN - 105063486. Corporate Author: Comprehensive Sickle Cell Centers (CSCC) Clinical Trial Consortium (CTC) Site Investigators. Language: English. Entry Date: 20100827. Revision Date: 20200708. Publication Type: journal article AU - Dampier, C. AU - Lieff, S. AU - Lebeau, P. AU - Rhee, S. AU - McMurray, M. AU - Rogers, Z. AU - Smith-Whitley, K. AU - Wang, W. AU - Dampier, Carlton AU - Lieff, Susan AU - LeBeau, Petra AU - Rhee, Seungshin AU - McMurray, Marsha AU - Rogers, Zora AU - Smith-Whitley, Kim AU - Wang, Winfred DB - cin20 DO - 10.1002/pbc.22497 DP - EBSCOhost IS - 3 KW - Anemia, Sickle Cell -- Complications Quality of Life Activities of Daily Living Adolescence Asthma -- Complications Child Child, Preschool Fatigue -- Complications Female Hospitalization Human Male Pain Parents -- Psychosocial Factors Questionnaires Scales N1 - research. Journal Subset: Biomedical; Peer Reviewed; USA. Instrumentation: Health-Related Quality of Life (HRQOL); Health Behavior Scale (HBS). Grant Information: U54 HL070585-01/HL/NHLBI NIH HHS/United States. NLM UID: 101186624. PMID: NLM20658620. PY - 2010 SN - 1545-5009 SP - 485-494 ST - Health-related quality of life in children with sickle cell disease: a report from the Comprehensive Sickle Cell Centers Clinical Trial Consortium T2 - Pediatric Blood & Cancer TI - Health-related quality of life in children with sickle cell disease: a report from the Comprehensive Sickle Cell Centers Clinical Trial Consortium UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105063486&site=ehost-live&scope=site VL - 55 ID - 617 ER - TY - JOUR AB - Objectives: The study objective was to evaluate the effectiveness of homeopathic medicines for the prevention and treatment of migraine in children. Design: This was an observational, prospective, open, nonrandomized, noncomparative, multicenter study. Setting/location: The study was conducted in 12 countries worldwide. Subjects: Fifty-nine (59) physicians trained in the prescription of homeopathic medicines and 168 children, aged 5-15 years, with definite or probable migraine diagnosed using International Headache Society 2004 criteria were the subjects in this study. Interventions: Physicians were given complete freedom in terms of treatment prescription; thus, prescriptions were individualized for each patient. Outcome measures: The frequency, intensity, and duration of migraine attacks in the 3 months prior to inclusion were compared with those during the 3-month follow-up period. Pertinent data were collected using questionnaires completed by the doctor and the patient or his/her parent/guardian. The secondary outcome measure was the impact of homeopathic medicines on education, measured as absence from school. Results: The frequency, severity, and duration of migraine attacks decreased significantly during the 3-month follow-up period (all p<0.001). Preventive treatment during this time consisted of homeopathic medicines in 98% of cases (mean=2.6 medicines/patient). Children spent significantly less time off school during follow-up than before inclusion (2.0 versus 5.5 days, respectively; p<0.001). The most common preventive medicines used were Ignatia amara (25%; mainly 9C), Lycopodium clavatum (22%), Natrum muriaticum (21%), Gelsemium (20%), and Pulsatilla (12%; mainly 15C). Homeopathy alone was used for the treatment of migraine attacks in 38% of cases. The most commonly used medicines were Belladonna (32%; mainly 9C), Ignatia amara (11%; mainly 15C), Iris versicolor (10%; mainly 9C), Kalium phosphoricum (10%; mainly 9C), and Gelsemium (9%; mainly 15C and 30C). Conclusions: The results of this study demonstrate the interest of homeopathic medicines for the prevention and treatment of migraine attacks in children. A significant decrease in the frequency, severity, and duration of migraine attacks was observed and, consequently, reduced absenteeism from school. AN - 104315826. Language: English. Entry Date: 20130215. Revision Date: 20200708. Publication Type: Journal Article AU - Danno, Karine AU - Colas, Aurélie AU - Masson, Jean-Louis AU - Bordet, Marie-France DB - cin20 DO - 10.1089/acm.2011.0821 DP - EBSCOhost IS - 2 KW - Migraine -- Therapy -- In Infancy and Childhood Homeopathy -- In Infancy and Childhood Migraine -- Prevention and Control -- In Infancy and Childhood Human Funding Source France Child Child Health Adolescence Adolescent Health Child, Preschool Treatment Outcomes Descriptive Statistics Male Female Nonexperimental Studies Prospective Studies Multicenter Studies Alternative Therapies Comparative Studies Questionnaires Absenteeism Homeopathy -- Methods Chi Square Test T-Tests N1 - research; tables/charts. Journal Subset: Alternative/Complementary Therapies; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Pain and Pain Management; Pediatric Care. Grant Information: This study was funded by Boiron Laboratories.. NLM UID: 9508124. PMID: NLM22978244. PY - 2013 SN - 1075-5535 SP - 119-123 ST - Homeopathic Treatment of Migraine in Children: Results of a Prospective, Multicenter, Observational Study T2 - Journal of Alternative & Complementary Medicine TI - Homeopathic Treatment of Migraine in Children: Results of a Prospective, Multicenter, Observational Study UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104315826&site=ehost-live&scope=site VL - 19 ID - 535 ER - TY - JOUR AB - Abstract: The aims of this study were: 1) to describe how parents assess pain in their child with Down syndrome; and 2) to examine the relationship between pain assessment and decisions by parents to intervene to relieve pain in the child. Twelve parents of school-age children with Down syndrome (ages 6-12 years) were interviewed. Data analysis followed Spradley''s Developmental Research Sequence (1979). This included domain analysis, taxonomic analysis, componential analysis, and theme development. Four themes emerged from the data analysis. Theme 1: Being sensitive to verbal and behavioral attributes of pain in the child. Parents reported that they assessed pain in their child with Down syndrome through the child''s use of words to express pain, pointing or showing pain location, crying, changes in usual activities, and seeking closeness to the parent. Theme 2: Recognizing emotional and social responses to pain. Parents reported that emotional responses (e.g., anger, fear, frustration, acting out) were part of the pain expressions of their child with Down syndrome. Theme 3: Identifying differences in pain expressions between child and siblings. Parents used strategies to assess pain based on their beliefs that the child was less verbal, slower to complain, and less bothered by pain than siblings. Strategies included questioning the child to elicit self-reporting of pain and observing the child''s behaviors. Theme 4: Making decisions to intervene. Parents reported that actions to relieve pain in their child with Down syndrome included more psychologic measures than physical measures, but otherwise no differences were noted in the actions taken for the child and the child''s siblings. AD - University of Texas Health Science Center, San Antonio, Texas AN - 104948967. Language: English. Entry Date: 20110126. Revision Date: 20200708. Publication Type: Journal Article AU - Davies, R. B. DB - cin20 DO - 10.1016/j.pmn.2009.09.003 DP - EBSCOhost IS - 4 KW - Pain Measurement -- In Infancy and Childhood Parental Role Decision Making, Family Human Male Female Adult Child Interviews Thematic Analysis Texas Research Subject Recruitment Convenience Sample Ethnographic Research Middle Age N1 - research; tables/charts. Journal Subset: Blind Peer Reviewed; Core Nursing; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 100890606. PMID: NLM21095600. PY - 2010 SN - 1524-9042 SP - 259-267 ST - Pain in Children with Down Syndrome: Assessment and Intervention by Parents T2 - Pain Management Nursing TI - Pain in Children with Down Syndrome: Assessment and Intervention by Parents UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104948967&site=ehost-live&scope=site VL - 11 ID - 604 ER - TY - JOUR AB - Children in primary school can be very disabled by chronic fatigue syndrome or ME (CFS/ME). The clinical presentation in this age group (under 12 years old) is almost identical to that in older children. AIM: To describe children who presented to the Bath paediatric CFS/ME service under the age of 12 years. METHOD: Inventories measuring fatigue, pain, functional disability, anxiety, family history and symptoms were collected prospectively for all children presenting to the Bath CFS/ME service between September 2004 and April 2007. Data from children who presented to the service under the age of 12 are described and compared to those who presented at age 12 or older. RESULTS: 178 children (under the age of 18) were diagnosed as having CFS/ME using the RCPCH criteria out of 216 children assessed. The mean age at assessment for children with CFS/ME was 14.5 years old (SD 2.9). Thirty-two (16%) children were under 12 years at the time of assessment, four children were under 5 years and the youngest child was 2 years old. Children under 12 were very disabled with mean school attendance of just over 40% (average 2 days a week), Chalder fatigue score of 8.29 (CI 7.14 to 9.43 maximum possible score = 11) and pain visual analogue score of 39.7 (possible range 0-100). Comparison with children aged 12 or older showed that both groups were remarkably similar at assessment. Twenty-four out of the 26 children with complete symptom lists would have been diagnosed as having CFS/ME using the stricter adult Centers of Disease Control and prevention (CDC) criteria. CONCLUSION: Disability in the under-12 age group was high, with low levels of school attendance, high levels of fatigue, anxiety, functional disability and pain. The clinical pattern seen is almost identical to that seen in older children, and the majority of children would also be diagnosed as having CFS/ME using the stricter adult definition. AD - Department of Women and Children's Health, Southmead Hospital, Bristol, UK. AN - 105741800. Language: English. Entry Date: 20080613. Revision Date: 20200708. Publication Type: Journal Article AU - Davies, S. AU - Crawley, E. DB - cin20 DO - 10.1136/adc.2007.126649 DP - EBSCOhost IS - 5 KW - Fatigue Syndrome, Chronic -- Diagnosis Adolescence Anxiety -- Etiology Child Child, Preschool England Fatigue Syndrome, Chronic -- Complications Fatigue -- Etiology Female Male Pain -- Etiology Prospective Studies Human N1 - research. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 0372434. PMID: NLM18192312. PY - 2008 SN - 0003-9888 SP - 419-421 ST - Chronic fatigue syndrome in children aged 11 years old and younger T2 - Archives of Disease in Childhood TI - Chronic fatigue syndrome in children aged 11 years old and younger UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105741800&site=ehost-live&scope=site VL - 93 ID - 681 ER - TY - JOUR AB - Objective: To assess the prevalence of menstrual hygiene management (MHM) knowledge and practices among adolescent schoolgirls in Indonesia, and assess factors associated with poor MHM and school absenteeism due to menstruation.Methods: A cross-sectional survey enrolled a representative sample of urban and rural school-going girls aged 12-19 years in four provinces of Indonesia. A semi-structured, self-administered questionnaire obtained socio-demographic characteristics, knowledge, practices and attitudes related to menstruation, MHM and school absenteeism. School water, sanitation and hygiene (WASH) facilities were also assessed. Univariate weighted population prevalence was estimated and multivariable logit regression analyses applied to explore associations.Results: A total of 1159 adolescent girls with a mean age of 15 years (SD = 1.8) participated. Most girls (90.8%, 95% confidence interval (95% CI) = 79.7-96.1) had reached menarche. Over half (64.1%, 95% CI = 49.9-76.2) reported poor MHM practices, and 11.1% (95% CI = 8.1-15.2) had missed one or more days of school during their most recent menstrual period. Poor MHM practices were associated with rural residence (Adjusted odds ratio (AOR) = 1.73, 95% CI = 1.13-2.64), province (various AOR), lower school grade (AOR = 1.69, 95% CI = 1.05-2.74) and low knowledge of menstruation (AOR = 3.49, 95% CI = 1.61-7.58). Absenteeism was associated with living in rural areas (AOR = 3.96, 95% CI = 3.02-5.18), province (various AOR), higher school grade (AOR = 3.02, 95% CI = 2.08-4.38), believing menstruation should be kept secret (AOR = 1.47, 95% CI = 1.03-2.11), experiencing serious menstrual pain (AOR = 1.68, 95% CI = 1.06-2.68) and showed mixed associations with school WASH facilities.Conclusions: High prevalence of poor MHM and considerable school absenteeism due to menstruation among Indonesian girls highlight the need for improved interventions that reach girls at a young age and address knowledge, shame and secrecy, acceptability of WASH infrastructure and menstrual pain management. Objectif: Evaluer la prévalence des connaissances et pratiques en matière de gestion de l'hygiène menstruelle chez les écolières adolescentes en Indonésie, ainsi que les facteurs associés à une mauvaise gestion de l'hygiène menstruelle et à l'absentéisme scolaire dû à la menstruation. Méthodes: Une enquête transversale a recruté un échantillon représentatif de filles urbaines et rurales scolarisées, âgées de 12 à 19 ans dans quatre provinces d'Indonésie. Un questionnaire semi‐structuré et auto‐administré a permis d'obtenir les caractéristiques sociodémographiques, les connaissances, les pratiques et les attitudes liées aux menstruations, à la gestion de l'hygiène menstruelle et à l'absentéisme scolaire. Les installations d'eau, de sanitaires et l'hygiène à l'école ont également été évaluées. La prévalence pondérée univariée de la population a été estimée et des analyses de régression logit multivariées ont été appliquées pour explorer les associations. Résultats: Au total, 1.159 adolescentes d'un âge moyen de 15 ans (ds = 1,8) ont participé. La plupart des filles (90,8%, intervalle de confiance à 95% (IC95%): 79,7 à 96,1) avaient atteint les premières règles. Plus de la moitié (64,1%, IC95%: 49,9 à 76,2) ont déclaré des pratiques médiocres de la gestion de l'hygiène menstruelle et 11,1% (IC95%: 8,1 à 15,2) avaient manqué un jour d'école au cours de leur dernière période menstruelle. Les mauvaises pratiques de gestion de l'hygiène menstruelle étaient associées à la résidence en milieu rural (AOR = 1,73 ; IC95%: 1,13‐2,64), à la province (divers AOR), au niveau scolaire inférieur (AOR = 1,69 ; IC95%: 1,05‐2,74) et à une faible connaissance de la menstruation (AOR = 3,49 ; IC95%: 1,61‐7,58). L'absentéisme était associé au fait de vivre dans des zones rurales (AOR = 3,96 ; IC95%: 3,02‐5,18), la province (divers AOR), au niveau scolaire plus élevé (AOR = 3,02 ; IC95%: 2,08‐4,38), à la croyance que les règles devaient être gardées secrètes (AOR = 1,47 ; IC95%: 1,03‐2,11), souffrir de douleurs menstruelles sévères (AOR = 1,68 ; IC95% : 1,06‐2,68) et présentait des associations mixtes avec les installations scolaires d'eau, d'hygiène et de sanitaires. Conclusions: La prévalence élevée de mauvaises gestions de l'hygiène menstruelle et l'absentéisme scolaire considérable dû à la menstruation chez les filles indonésiennes soulignent le besoin d'interventions améliorées qui touchent les filles dès leur plus jeune âge et abordent la connaissance, la honte et le secret, l'acceptabilité de l'infrastructure d'eau, d'hygiène et de sanitaires et la gestion de la douleur menstruelle. AD - Maternal and Child Health Program, Burnet Institute, Melbourne Vic, Australia WaterAid Australia, Melbourne Vic, Australia UNICEF, Jakarta Indonesia SurveyMETER, Sleman Yogyakarta Indonesia Department of Epidemiology and Preventive Medicine, Monash University, Melbourne Vic, Australia Judith Lumley Centre, La Trobe University, Melbourne Vic, Australia Aliansi Remaja Independen, Jakarta Indonesia P.T Towards Sustainable Businesses, Jakarta Indonesia Ministry of Health, Government of Indonesia, Jakarta Indonesia Ministry of Education and Culture, Government of Indonesia, Jakarta Indonesia International Centre for Reproductive Health, Department of Obstetrics and Gynaecology, Ghent University, Ghent Belgium Murdoch Children's Research Institute, Melbourne Vic, Australia AN - 133371960. Language: English. Entry Date: In Process. Revision Date: 20191202. Publication Type: journal article AU - Davis, Jessica AU - Macintyre, Alison AU - Odagiri, Mitsunori AU - Suriastini, Wayan AU - Cordova, Andreina AU - Huggett, Chelsea AU - Agius, Paul A. AU - Faiqoh AU - Budiyani, Anissa Elok AU - Quillet, Claire AU - Cronin, Aidan A. AU - Diah, Ni Made AU - Triwahyunto, Agung AU - Luchters, Stanley AU - Kennedy, Elissa DB - cin20 DO - 10.1111/tmi.13159 DP - EBSCOhost IS - 12 KW - Adolescent Behavior Menstruation -- Psychosocial Factors Surveys Attitude to Health Absenteeism Hygiene Human Cross Sectional Studies Adolescence Schools Indonesia Students -- Statistics and Numerical Data Female Young Adult Students -- Psychosocial Factors Adult Validation Studies Comparative Studies Evaluation Research Multicenter Studies Questionnaires Scales N1 - research. Journal Subset: Biomedical; Europe; UK & Ireland. Instrumentation: Dissociative Experiences Scale (DES); Life Experiences Survey (LES); Attitudes to Treatment Questionnaire (ATQ). Grant Information: //UNICEF Indonesia/. NLM UID: 9610576. PMID: NLM30286270. PY - 2018 SN - 1360-2276 SP - 1350-1363 ST - Menstrual hygiene management and school absenteeism among adolescent students in Indonesia: evidence from a cross-sectional school-based survey T2 - Tropical Medicine & International Health TI - Menstrual hygiene management and school absenteeism among adolescent students in Indonesia: evidence from a cross-sectional school-based survey UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=133371960&site=ehost-live&scope=site VL - 23 ID - 278 ER - TY - JOUR AB - Children's response to the death of a sibling has not often been examined, however, some previous studies refer to this experience as a potential trauma to the child which may have long-term effects. An integrative review was performed to systematize the available knowledge about the grief of a child who has lost a sibling. The data was collected in September 2014 and a research protocol was created with its descriptors and exclusion and inclusion criteria. The body of the initial analysis was composed of 39 studies. Sibling bereavement may manifest itself in numerous negative symptoms, such as guilt, fear, sadness, despair, inferiority, concern, loneliness and depression. The grieving children also frequently suffer from sleep disorders, enuresis, anorexia, somatic complaints, abdominal pain and headaches. These children may have difficulty expressing their feelings, and think they are not recognised in their sorrow, these feelings can lead to social isolation and early school leaving or low attainment levels. These reactions depend on variables, which should be explored. In order for there to be an improvement in the nursing care given to a child/adolescent grieving the death of a sibling, it is essential to know the different manifestations of grief, so that we can strive towards emotionally balanced development. As reações da criança e do adolescente em relação à morte de um irmão têm sido pouco estudadas, embora os estudos refiram que tal experiência pode ser potencialmente traumática para a criança/adolescente e os efeitos duradouros. Realizou-se uma revisão integrativa da literatura com o objetivo de sistematizar e analisar a produção científica existente relacionada com a vivência do processo do luto fraterno da criança/adolescente. A colheita de dados foi efetuada em setembro de 2014 e o protocolo de pesquisa com respetivos descritores e critérios de inclusão e exclusão foi definido. Obteve-se uma amostra de 39 estudos. O luto das crianças pode ser caracterizado por culpa, medo, tristeza, desespero, inferioridade, preocupação, solidão e depressão. São também frequentes as perturbações do sono, enurese, anorexia, queixas psicossomáticas, dor abdominal e cefaleia. Podem sentir dificuldade em expressar os sentimentos, parecendo-lhes que tal não é valorizado o que pode, por vezes, conduzir ao isolamento social, ao abandono ou baixo rendimento escolar. Estas reações dependem de variáveis que devem ser aprofundadas para o nosso contexto atual. Para uma melhor prestação de cuidados de enfermagem à criança/adolescente em luto fraterno, é essencial conhecer as suas diferentes expressões do luto, de modo a contribuir para um posterior crescimento emocional equilibrado. AD - Enfermeira, Hospital Dona Estefânia AN - 113662880. Language: Portuguese. Entry Date: 20180412. Revision Date: 20191107. Publication Type: Article AU - De Barros Ramos, SÍLvia DB - cin20 DP - EBSCOhost IS - 2 KW - Bereavement Siblings -- Psychosocial Factors Child Adolescence Grief Death Nursing Care N1 - tables/charts. Journal Subset: Continental Europe; Double Blind Peer Reviewed; Europe; Nursing. PY - 2015 SN - 0873-8904 SP - 3-17 ST - O Luto Fraterno durante a Infância e Adolescência: Revisão Integrativa da Literatura T2 - Pensar Enfermagem TI - O Luto Fraterno durante a Infância e Adolescência: Revisão Integrativa da Literatura UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=113662880&site=ehost-live&scope=site VL - 19 ID - 449 ER - TY - JOUR AB - Purpose. To describe the outcome of a multidisciplinary pain management program for children and adolescents with chronic musculoskeletal pain. Methods. Study design: exploratory retrospective cohort study. The study sample consisted of a cohort of 70 children and adolescents (age: 8 - 21 years) with chronic musculoskeletal pain who completed a 3-month inpatient multidisciplinary pain management program. The program consisted of graded physical exercises, graded activities and counseling of the children and their parents. Assessed were motor and social activities, pain intensity, global assessment of physical functioning and psychosocial well-being (by patient and physician), understanding of the pain process and reduction of medical consumption. Assessments were performed at pre-admission, day of admission, day of discharge and at three months after discharge. Data collection took place over a 10-year period. Results. Compared to admission, at discharge there were significant improvements in motor performances, school attendance, reduction of pain scores, understanding of the chronic pain process and reduction of medical consumption. Results remained stable at follow-up after three months. Conclusion. The results of this study indicate that a multidisciplinary pain management program for children and adolescents with chronic musculoskeletal pain may be effective. AD - Center for Rehabilitation, University Medical Center Groningen, University of Groningen, Groningen AN - 105887927. Language: English. Entry Date: 20080418. Revision Date: 20170802. Publication Type: Journal Article AU - De Blécourt, A. C. E. AU - Preuper, H. R. S. AU - Van Der Schans, C. P. AU - Groothoff, J. W. AU - Reneman, M. F. DB - cin20 DP - EBSCOhost IS - 1 KW - Multidisciplinary Care Team -- In Infancy and Childhood Musculoskeletal System -- Pathology -- In Infancy and Childhood Pain -- Rehabilitation -- In Infancy and Childhood Treatment Outcomes -- In Infancy and Childhood Adolescence Adult Child Clinical Assessment Tools Counseling Data Analysis Software Descriptive Statistics Exploratory Research Functional Assessment International Classification of Functioning, Disability, and Health Pain Measurement Paired T-Tests Physical Therapists Pretest-Posttest Design Prospective Studies Record Review Retrospective Design Therapeutic Exercise Visual Analog Scaling Human N1 - research; tables/charts. Journal Subset: Allied Health; Europe; Peer Reviewed; UK & Ireland. NLM UID: 9207179. PMID: NLM17852248. PY - 2008 SN - 0963-8288 SP - 13-20 ST - Preliminary evaluation of a multidisciplinary pain management program for children and adolescents with chronic musculoskeletal pain T2 - Disability & Rehabilitation TI - Preliminary evaluation of a multidisciplinary pain management program for children and adolescents with chronic musculoskeletal pain UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105887927&site=ehost-live&scope=site VL - 30 ID - 691 ER - TY - JOUR AB - BACKGROUND: The association between Dientamoeba (D.) fragilis and the aetiology of functional gastrointestinal disorders (FGID) in children is unclear. AIM: The aim of this retrospective case-control study is to clarify the clinical relevance of D. fragilis in children with chronic abdominal pain. METHODS: From April 2011 until April 2013, a total of 132 patients with chronic abdominal pain (AP), aged 8-18years, referred to a non-academic hospital, and 77 control patients, aged 8-18years without gastrointestinal symptoms referred to a psychiatric hospital, were included in the study. D. fragilis was diagnosed by real-time PCR in faecal samples. Symptomatic children without a D. fragilis infection fulfilled the ROME III criteria for AP-related FGID (AP-FGID). Clinical data were retrospectively analysed by examining patients' hospital records from the Jeroen Bosch Hospital and Herlaarhof in The Netherlands. RESULTS: D. fragilis was detected in 57 patients with chronic AP (43.2%) and in 39 controls (50.6%) (p=0.255). No significant differences in symptomatology were found between D. fragilis-infected children and children fulfilling the criteria for AP-FGID. Parasitological eradication was achieved in 61.7% of patients after treatment with metronidazole or clioquinol, while clinical improvement occurred in only 40.4% of patients (p=0.435). CONCLUSIONS: There were no differences in symptoms comparing children with and without D fragilis infection. Furthermore, no relation was found between clinical and microbiological response after treatment for D. fragilis. This retrospective study suggests that there is no association between chronic AP and D. fragilis infection. AD - Department of Pediatrics, Jeroen Bosch Hospital, 's Hertogenbosch, Brabant, The Netherlands. Department of Pediatric Gastroenterology & Nutrition, Emma Children's Hospital/Academic Medical Center, Amsterdam, The Netherlands. Jeroen Bosch Academy, Jeroen Bosch Hospital, 's Hertogenbosch, The Netherlands. Department of Pediatrics, Jeroen Bosch Hospital, 's Hertogenbosch, Brabant, The Netherlands Psychiatric hospital Herlaarhof, Vught, The Netherlands. AN - 103853897. Language: English. Entry Date: 20150213. Revision Date: 20200708. Publication Type: Journal Article AU - de Jong, Marin J. AU - Korterink, Judith J. AU - Benninga, Marc A. AU - Hilbink, Mirrian AU - Widdershoven, J. AU - Deckers-Kocken, Judith M. DB - cin20 DO - 10.1136/archdischild-2014-305942 DP - EBSCOhost IS - 12 KW - Abdominal Pain Gastrointestinal Diseases Protozoa Protozoan Infections Abdominal Pain -- Diagnosis Abdominal Pain -- Drug Therapy Adolescence Antiprotozoal Agents -- Therapeutic Use Case Control Studies Child Chronic Disease Feces Female Gastrointestinal Diseases -- Diagnosis Gastrointestinal Diseases -- Drug Therapy Human Male Metronidazole -- Therapeutic Use Polymerase Chain Reaction Prevalence Quinolines -- Therapeutic Use Retrospective Design N1 - research. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Pediatric Care. NLM UID: 0372434. PMID: NLM25053737. PY - 2014 SN - 0003-9888 SP - 1109-1113 ST - Dientamoeba fragilis and chronic abdominal pain in children: a case-control study T2 - Archives of Disease in Childhood TI - Dientamoeba fragilis and chronic abdominal pain in children: a case-control study UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=103853897&site=ehost-live&scope=site VL - 99 ID - 467 ER - TY - JOUR AB - Objective: Dental students have high levels of anxiety that can affect not only academic performance but also increase the risk for other diseases. It is believed that the increase in the incidence of chronic orofacial pain in temporomandibular disorders (TMDs) may have an impact on the quality of life and general health of subjects. The aim of this study was to evaluate the prevalence of TMD in dental students and its association with general health, quality of life, and anxiety. Method and Materials: Ninety students were evaluated by four questionnaires to determine the prevalence and sever ity of TMD (Fonseca's questionnaire) and to quantify general health (General Health Questionnaire - GHQ), quality of life (World Health Organization Quality of Life - Brief version - WHOQOLbrief) and anxiety levels (State-Trait Anxiety Index - STAI). Results: Approximately 58.9% of dental students presented TMD. Among the indicators of general health, psychologic stress (P = .010), distrust in their own performance (P = .012), and psychosomatic disorders (P = .020) showed a statistically significant difference with the presence of TMD. The four areas proposed in the questionnaire regarding quality of life, such as physical (P = .016), psychologic (P < .001), social (P = .045), and environmental (P = .017) factors also showed significant differences with the presence of TMD. Conclusion: A high prevalence of TMD was observed in dental students. In addition, some psychologic domains are important psychosocial indicators associated with the presence of TMDs. AD - PhD Student, State University of São Paulo, Araraquara School of Dentistry, Department of Dental Materials and Prosthodontics, Araraquara, SP, Brazil PhD Student, University of Sao Paulo, Ribeirao Preto School of Dentistry, Department of Dental Materials and Prosthodontics, Ribeirao Preto, SP, Brazil Professor, Federal University of Rio Grande do Norte, Department of Dentistry, Natal, RN, Brazil PhD Student, University of Sao Paulo, Bauru School of Dentistry, Department of Orthodontics, Ribeirao Preto, SP, Brazil AN - 122030511. Language: English. Entry Date: 20170328. Revision Date: 20190712. Publication Type: Article AU - de Melo Rocha, Cibele Oliveira AU - Peixoto, Raniel Fernandes AU - de Resende, Camila Maria Bastos Machado AU - de Medeiros Alves, Arthur César AU - da Costa Oliveira, Ângelo Giuseppe Roncalli AU - Seabra Barbosa, Gustavo Augusto DB - cin20 DO - 10.3290/j.qi.a37128 DP - EBSCOhost IS - 3 KW - Students, Dental -- Psychosocial Factors -- Brazil Temporomandibular Joint Diseases -- Epidemiology -- Brazil Facial Pain -- Psychosocial Factors Anxiety Quality of Life Health State-Trait Anxiety Inventory Questionnaires Psychological Tests Human Female Male Cross Sectional Studies Descriptive Statistics Data Analysis Software P-Value Chi Square Test T-Tests Adolescence Young Adult Brazil N1 - research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Instrumentation: General Health Questionnaire (GHQ); State-Trait Anxiety Inventory (STAI)(Spielberger); World Health Organization Quality of Life Measure-Brief Version (WHOQOL-BREF); Fonseca¿s Questionnaire. NLM UID: 0342677. PY - 2017 SN - 0033-6572 SP - 241-249 ST - Psychosocial aspects and temporomandibular disorders in dental students T2 - Quintessence International TI - Psychosocial aspects and temporomandibular disorders in dental students UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=122030511&site=ehost-live&scope=site VL - 48 ID - 372 ER - TY - JOUR AB - PURPOSE: A case of rhabdomyolysis associated with the use of Hydroxycut is reported. SUMMARY: An 18-year-old Caucasian man arrived at an urgent care center complaining of bilateral leg pain and weakness. His creatine kinase (CK) concentration was 13,220 IU/L. He was diagnosed with rhabdomyolysis and instructed to go to the emergency room. He admitted to decreased urine output for four to five days before hospital admission. He had no significant past medical history, and his medications before symptom onset included Hydroxycut four caplets by mouth daily, naproxen sodium 220 mg by mouth as needed for pain, dextroamphetamine saccharate-amphetamine salts (Adderall) 15 mg by mouth once five days prior for a school examination, and hydrocodone-acetaminophen and cyclobenzaprine for pain. His social history revealed a recent increase in his exercise regimen, and his last alcoholic beverage was consumed five days prior. Upon admission, laboratory tests revealed elevated concentrations of CK, serum creatinine (SCr), aspartate transaminase, alanine transaminase (ALT), and alkaline phosphatase. The patient was diagnosed with rhabdomyolysis and treated with intravenous hydration. The patient's leg tenderness was reduced, and he was discharged with instructions to stop Hydroxycut, increase fluid intake, avoid alcohol consumption, and limit physical activity for the next week. Two weeks after hospital discharge, the patient's CK and liver enzyme values returned to normal, excluding ALT and SCr, which remained slightly elevated, and his lower-extremity tenderness fully resolved. CONCLUSION: An 18-year-old Caucasian man with no significant medical history developed rhabdomyolysis possibly associated with the ingestion of Hydroxycut in addition to his increased exercise regimen. AD - Department of Pharmacy Services, University of Utah, Salt Lake City, UT 84132, USA. sarah.dehoney@hsc.utah.edu AN - 105631945. Language: English. Entry Date: 20090306. Revision Date: 20150711. Publication Type: Journal Article AU - Dehoney, S. AU - Wellein, M. DB - cin20 DO - 10.2146/ajhp070640 DP - EBSCOhost IS - 2 KW - Dietary Supplements -- Adverse Effects Rhabdomyolysis -- Chemically Induced Adolescence Creatine Kinase -- Blood Male Muscle Weakness -- Etiology Pain -- Etiology Plant Extracts -- Adverse Effects White Persons N1 - case study; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Peer Reviewed; USA. NLM UID: 9503023. PMID: NLM19139478. PY - 2009 SN - 1079-2082 SP - 142-148 ST - Rhabdomyolysis associated with the nutritional supplement Hydroxycut [corrected] [published erratum appears in AM J HEALTH SYST PHARM AJHP 2009 Feb 15;66(4):328] T2 - American Journal of Health-System Pharmacy TI - Rhabdomyolysis associated with the nutritional supplement Hydroxycut [corrected] [published erratum appears in AM J HEALTH SYST PHARM AJHP 2009 Feb 15;66(4):328] UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105631945&site=ehost-live&scope=site VL - 66 ID - 668 ER - TY - JOUR AB - The aim of this study was to assess the efficacy of self-hypnosis in a therapeutic education program (TEP) for the management of chronic pain in 26 children aged 7 to 17 years. Outcomes of the study were a total or a partial (at least 1) achievement of the therapeutic goals (pain, quality of sleeping, schooling, and functional activity). Sixteen patients decreased their pain intensity, 10 reached all of their therapeutic goals, and 9 reached them partially. Self-hypnosis was the only component of the TEP associated with these improvements. The current study supports the efficacy of self-hypnosis in our TEP program for chronic pain management in children. AD - Robert Debré University Hospital, Paris Diderot University, and Paris Descarte University, France Robert Debré University Hospital, Paris Diderot University, France AN - 127211129. Language: English. Entry Date: 20180113. Revision Date: 20190625. Publication Type: Article AU - Delivet, Honorine AU - Dugue, Sophie AU - Ferrari, Alexis AU - Postone, Silvia AU - Dahmani, Souhayl DB - cin20 DO - 10.1080/00207144.2018.1396109 DP - EBSCOhost IS - 1 KW - Program Evaluation Self Care Hypnosis Quality of Life Chronic Pain -- Therapy -- In Infancy and Childhood Chronic Pain -- Therapy -- In Adolescence Human Male Female Child Adolescence Clinical Trials Prospective Studies Retrospective Design Outcomes of Education N1 - clinical trial; research; tables/charts. Journal Subset: Alternative/Complementary Therapies; Peer Reviewed; USA. NLM UID: 0376166. PY - 2018 SN - 0020-7144 SP - 43-55 ST - Efficacy of Self-hypnosis on Quality of Life For Children with Chronic Pain Syndrome T2 - International Journal of Clinical & Experimental Hypnosis TI - Efficacy of Self-hypnosis on Quality of Life For Children with Chronic Pain Syndrome UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=127211129&site=ehost-live&scope=site VL - 66 ID - 326 ER - TY - JOUR AB - Adverse childhood experiences (ACEs; eg, parental divorce, physical or sexual abuse) are more prevalent in individuals with chronic pain compared with the general population. Both increased maternal ACEs and chronic pain have been associated with poor physical and emotional functioning in offspring. However, the mechanisms driving these associations are poorly understood. Thus, this cross-sectional study evaluated the relation between maternal ACEs, mothers' current functioning, and children's physical and emotional functioning in a sample of mothers with chronic pain and their 8- to 12-year-old children. Results indicated a higher prevalence of ≥1 ACE in this sample of mothers with chronic pain (84%) compared with normative data from a community sample of women. Higher maternal ACE scores corresponded with lower physical and social functioning, greater anxiety and depressive symptoms, greater fatigue and sleep disturbances, and greater pain intensity and pain interference in mothers. Higher maternal ACE scores significantly correlated with higher child self-reported depressive symptoms, but not somatic symptoms or functional impairment. A path model indicated that maternal depressive symptoms accounted for the relation between higher maternal ACE scores and children's depressive symptoms. Intervening on maternal depression among mothers with chronic pain may reduce the impact of intergenerational ACE transmission. Perspective: This article presents evidence regarding the intergenerational impact of ACEs in a large sample of mothers with chronic pain and their school-aged children. Maternal depressive symptoms accounted for the relation between maternal ACEs and children's depressive symptoms providing evidence regarding targets for preventive interventions. AD - Department of Pediatrics, Institute on Development and Disability, Oregon Health & Science University, Portland, Oregon Department of Psychology, Portland State University, Portland, Oregon Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, California AN - 138889405. Language: English. Entry Date: In Process. Revision Date: 20201003. Publication Type: journal article. Journal Subset: Biomedical AU - Dennis, Catlin H. AU - Clohessy, Denae S. AU - Stone, Amanda L. AU - Darnall, Beth D. AU - Wilson, Anna C. DB - cin20 DO - 10.1016/j.jpain.2019.04.004 DP - EBSCOhost IS - 10 KW - Children of Impaired Parents -- Statistics and Numerical Data Mothers -- Statistics and Numerical Data Depression -- Epidemiology Chronic Pain -- Epidemiology Male Cross Sectional Studies Female Child Adult Self Report Clinical Assessment Tools Impact of Events Scale Psychological Tests Questionnaires Social Readjustment Rating Scale N1 - Peer Reviewed; USA. Instrumentation: Maternal Confidence Questionnaire (MCQ) (Parker and Zahr); General Health Questionnaire (GHQ); Addenbrooke's Cognitive Examination (ACE); Functional Living Index: Cancer (FLIC) (Schipper et al); Impact of Events Scale (IES); Social Readjustment Rating Scale (SRRS) (Holmes and Rahe). Grant Information: R01 HD082200/HD/NICHD NIH HHS/United States. NLM UID: 100898657. PMID: NLM31005595. PY - 2019 SN - 1526-5900 SP - 1209-1217 ST - Adverse Childhood Experiences in Mothers With Chronic Pain and Intergenerational Impact on Children T2 - Journal of Pain TI - Adverse Childhood Experiences in Mothers With Chronic Pain and Intergenerational Impact on Children UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=138889405&site=ehost-live&scope=site VL - 20 ID - 216 ER - TY - JOUR AB - Objective: To present a case of medial epicondylitis in an adolescent baseball pitcher that appeared to improve when addressing the upper extremity kinetic chain with a variety of conservative management strategies.Clinical Features: An 18-year-old right hand dominant high school baseball pitcher had recurring sharp pain in his right elbow. Previous trials of medication and physical therapy were only partially successful in resolving the problem. The patient's pain was rated as an 8 on a numerical pain scale during throwing activities. A variety of tender points were noted in the right upper extremity. The patient had discontinued playing competitive baseball due to the pain.Intervention and Outcome: The patient was treated 14 times over 15 weeks. Treatment included cervical, thoracic and upper extremity manipulation, soft tissue mobilization and progressive sport-specific training for the upper extremity. After the first treatment he was able to throw the ball and was able to continue throwing during the treatment program. The patient returned to league play after the treatment program.Conclusion: A course of conservative care addressing multiple elements of the upper extremity kinetic chain seemed beneficial for this athlete. AD - Practice of Chiropractic, PO Box 502, Prior Lake, MN 55372 AN - 106113553. Language: English. Entry Date: 20070706. Revision Date: 20150820. Publication Type: Journal Article AU - Devitt, B. M. DA - 2006 Fall DB - cin20 DP - EBSCOhost IS - 3 KW - Athletes Baseball Elbow -- Physiopathology Manipulation, Chiropractic Pain -- Therapy Adolescence Male N1 - case study. Journal Subset: Alternative/Complementary Therapies; Blind Peer Reviewed; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. PY - 2006 SN - 1556-3707 SP - 97-100 ST - User of conservative and sport-specific management strategies for a baseball pitcher with persistent elbow pain T2 - Journal of Chiropractic Medicine TI - User of conservative and sport-specific management strategies for a baseball pitcher with persistent elbow pain UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106113553&site=ehost-live&scope=site VL - 5 ID - 725 ER - TY - JOUR AB - Complex regional pain syndrome (CRPS) is a clinically diagnosed chronic pain syndrome characterized by severe pain and functional disability following a minor injury. The affected limb often has evidence of changes in sensory, vasomotor, sudomotor/edema, and/or motor/tropic function. The diagnosis of CRPS in the pediatric population is increasingly common, especially among female adolescents. The pain experience of adolescents with CRPS is best understood using the biopsychosocial framework, and the most effective treatment programs target biological, psychological, and social factors. Treatment for CRPS is multidisciplinary and typically includes physical therapy, occupational therapy, and psychology. The parent-child dyad that develops when the child has CRPS is complex and characterized by significant psychological distress, ineffective parenting, and poor coping. The purpose of this article is to describe the role of parents in the treatment of adolescents with CRPS. To promote successful remission from pain and restoration of functional ability, parents should be included in treatment programs. Nurses caring for adolescents with CRPS can assist parents in developing adaptive parenting skills. harinBaldwinNIHR Clinical Doctoral Fellow, King's College London health visiting clinical academicandinnovationslead,LondonNorthWestHealthcareTrust.PatriciaKelly,healthvisitingassociatepracticeteacher,HealthVisitingClinicalAcademicHub,LondonNorthWestHealthcareTrust. AD - Advanced Practice Nurse, Developmental-Behavioral Pediatrics, Children's Specialized Hospital, New Brunswick, NJ AN - 121353599. Language: English. Entry Date: 20170222. Revision Date: 20190708. Publication Type: Article AU - Dickson, Shayleigh K. DB - cin20 DP - EBSCOhost IS - 1 KW - Complex Regional Pain Syndromes -- Therapy -- In Infancy and Childhood Parental Role Parenting Adolescence Child Female Mental Disorders Occupational Therapy Pain Measurement Physical Therapy Physicians Treatment Outcomes Complex Regional Pain Syndromes -- Diagnosis Coping Complex Regional Pain Syndromes -- Symptoms N1 - tables/charts. Journal Subset: Core Nursing; Nursing; Peer Reviewed; USA. NLM UID: 7505804. PY - 2017 SN - 0097-9805 SP - 16-39 ST - Including Parents in the Treatment Of Pediatric Complex Regional Pain Syndrome T2 - Pediatric Nursing TI - Including Parents in the Treatment Of Pediatric Complex Regional Pain Syndrome UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=121353599&site=ehost-live&scope=site VL - 43 ID - 380 ER - TY - JOUR AB - Background: Complaints in the musculoskeletal system often start early in life and back and neck pain in children are well-established predictors for similar problems in adulthood. Despite lack of evidence of effectiveness, manipulative therapy is one of the most commonly used treatment modalities for back and neck pain in children. The primary objective of this study is to evaluate the effectiveness of manipulative therapy when added to an approach consisting of manual soft tissue treatment, exercises and advice as needed, in children aged 9-15 complaining of back and neck pain. Method: The project is nested in the Childhood Health, Activity and Motor Performance School Study, which includes around 1200 children aged 9-15, who were all invited to participate in this randomized controlled trial in case they experienced back and/or neck pain during the two year inclusion period. Parents received text messages (SMS) on a weekly basis inquiring about the child's musculoskeletal pain. If pain was reported, the child was evaluated for inclusion into the trial and, if eligible, randomized into one of two intervention groups: 1. Pragmatic advice, manual soft tissue treatment and exercises 2. The above plus manipulative therapy By the end of data collection 237 children were included in the study. The primary outcome measure is number of recurrences of back and neck pain during the follow-up period (3-27 months). Secondary outcome measures are average duration of complaint time for each episode, total duration of complaint time, global perceived effect after two weeks, and change in pain intensity after 2 weeks. Baseline information includes quality of life, expectations to treatment, expectations to future course, age, gender, social class and physical education at school. Discussion: For most common non-traumatic musculoskeletal complaints no standardized and evidence based treatment strategy exists. We want to evaluate the effectiveness of manipulative therapy in addition to an approach consisting of manual soft tissue treatment, exercises and advice as needed, in children aged 9-15 complaining of back and neck pain. To our knowledge this is the first large scale randomized controlled trial investigating the effectiveness of commonly used treatments for back and neck pain in children. Trial registration: ClinicalTrials NCT01504698 AD - Department of Sports Science and Clinical Biomechanics, Faculty of Health Sciences, University of Southern Denmark, Campusvej 55, DK-5230 Odense M, Denmark Nordic Institute of Chiropractic and Clinical Biomechanics, Campusvej 55, DK-5230 Odense M, Denmark Institute of Regional Health Services Research, University of Southern Denmark, Winsloewparken 193, DK-5000 Odense C, Denmark Orthopaedic Department Hospital of Lillebaelt, Sports Medicine Clinic, Østre Hougvej 55, DK-5500 Middelfart, Denmark AN - 112597240. Language: English. Entry Date: 20180117. Revision Date: 20190208. Publication Type: Article AU - Dissing, Kristina Boe AU - Hartvigsen, Jan AU - Wedderkopp, Niels AU - Hestbæk, Lise DB - cin20 DO - 10.1186/s12998-016-0086-y DP - EBSCOhost KW - Back Pain -- Therapy -- Denmark Neck Pain -- Therapy -- In Infancy and Childhood Manual Therapy Denmark Randomized Controlled Trials Child Adolescence N1 - protocol; tables/charts. Journal Subset: Alternative/Complementary Therapies; Australia & New Zealand; Peer Reviewed. NLM UID: 101551481. PY - 2016 SN - 2045-709X SP - 1-10 ST - Conservative care with or without manipulative therapy in the management of back and neck pain in Danish children aged 9-15. Study protocol for a randomized controlled trial T2 - Chiropractic & Manual Therapies TI - Conservative care with or without manipulative therapy in the management of back and neck pain in Danish children aged 9-15. Study protocol for a randomized controlled trial UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=112597240&site=ehost-live&scope=site VL - 24 ID - 428 ER - TY - JOUR AB - Purpose: The aim of this study was to describe self-efficacy as a theoretical component of behavior change in various therapeutic treatments such as the management of SCD pain. Method: The participants were prepared to self-initiate the G1 for 5 to 10 minutes three times each day regardless of pain and also during each pain episode. As part of the GI training a tape or CD with guided imagery messages was provided. Participants were monitored for 4 weeks pre and 4 weeks post intervention (GI training). Children kept a daily record of pain episodes. During this time, children continued to record as before in their personal study diary: pain episodes (intensity and treatment), school attendance, and also the frequency of GI use. At the conclusion of this 4-week period, usual pain patterns (PAT), visual imagery ability (KIAQ), and disease specific self-efficacy scale were measured again. The Sickle Cell Self-Efficacy Scale (SCSES) is a new nine-item scale measuring disease-specific perceptions of self-efficacy. The instrument's developers established internal consistency by Cronbach's alpha of 0.89. Results: HI : Children with SCD who are trained in guided imageiy will have greater disease-specific self-efficacy following the training than they had prior to learning guided imagery; the hypothesis was tested and supported using t-tests of mean interval-level scores on the SCSES. Conclusion: Eighteen children had positive gained scores and sixteen children raised their scores more than one standard deviation above the mean score for this sample distribution. Greater self-efficacy scores are associated with better physical and psychological functioning. AD - Lehman College of the City University of New York, Bronx, NY 10468, USA AN - 111669284. Language: English. Entry Date: 20160310. Revision Date: 20180618. Publication Type: Article AU - Dobson, Cassandra DB - cin20 DO - 10.1016/j.apnr.2014.12.005 DP - EBSCOhost IS - 4 KW - Guided Imagery -- Utilization -- In Infancy and Childhood Self-Efficacy -- Evaluation -- In Infancy and Childhood Anemia, Sickle Cell Pain -- Prevention and Control -- In Infancy and Childhood Coping -- Evaluation -- In Infancy and Childhood Human Child Diaries Coefficient Alpha Guided Imagery -- Education Scales T-Tests Quasi-Experimental Studies Purposive Sample Hospitals, Pediatric Male Female Pain Measurement Questionnaires N1 - research; tables/charts. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Pain and Pain Management; Pediatric Care. Instrumentation: Faces Pain Scale (FPS); ickle Cell Self-Efficacy Scale (SCSE); Kids Imaging Ability Question­naire (KIAQ). NLM UID: 8901557. PY - 2015 SN - 0897-1897 SP - 384-390 ST - Outcome results of self-efficacy in children with sickle disease pain who were trained to use guided imagery T2 - Applied Nursing Research TI - Outcome results of self-efficacy in children with sickle disease pain who were trained to use guided imagery UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=111669284&site=ehost-live&scope=site VL - 28 ID - 436 ER - TY - JOUR AB - The article discusses a study related to test the effectiveness of guided imagery training on school age children diagnosed with sickle cell disease. Topics discussed include describing the changes in pain perception, analgesic use, and self-efficacy, SCD afflicts nearly 90,000 to 100,000 people in the U.S., and cognitive behavioral therapy. Other topics discussed include pain diary. AD - Assistant Professor of Nursing, Lehman College, the City University of New York, New York City Stone Foundation & Elise D. Fish Professor in Clinical Health, Care for the Underserved, Columbia University School of Nursing, New York City AN - 95445870. Language: English. Entry Date: 20140411. Revision Date: 20190103. Publication Type: Article AU - Dobson, Cassandra Elaine AU - Byrne, Mary Woods DB - cin20 DO - 10.1097/01.NAJ.0000445680.06812.6a DP - EBSCOhost IS - 4 KW - Pain -- Therapy -- In Infancy and Childhood Anemia, Sickle Cell -- Symptoms Self Care -- Education -- In Infancy and Childhood Guided Imagery -- Education -- In Infancy and Childhood Patient Education Pediatric Care Pain -- Etiology Pain -- Drug Therapy Analgesics -- Administration and Dosage Self-Efficacy Quasi-Experimental Studies Time Series Purposive Sample Outpatients Child Diaries Treatment Outcomes Education, Continuing (Credit) Questionnaires Record Review Interviews Clinical Assessment Tools Human Scales Ethnic Groups Family Characteristics Insurance, Health New York Descriptive Statistics Ambulatory Care Facilities Summated Rating Scaling Reliability and Validity Wong-Baker FACES Pain Rating Scale Activities of Daily Living Coping Health Resource Utilization Emergency Service -- Utilization Hospitalization Absenteeism Pilot Studies Convenience Sample Pretest-Posttest Design N1 - CEU; exam questions; questionnaire/scale; research; tables/charts. Note: For CE answer sheet see page 47.. Journal Subset: Core Nursing; Nursing; Peer Reviewed; USA. Special Interest: Pain and Pain Management; Pediatric Care. Instrumentation: Wong-Baker FACES Pain Rating Scale; Pain Assessment Tool (PAT); Kids Imaging Ability Questionnaire (KIAQ); Sickle Cell Self-Efficacy Scale (SCSES). NLM UID: 0372646. PY - 2014 SN - 0002-936X SP - 26-47 ST - Using Guided Imagery to Manage Pain in Young Children with Sickle Cell Disease T2 - AJN American Journal of Nursing TI - Using Guided Imagery to Manage Pain in Young Children with Sickle Cell Disease UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=95445870&site=ehost-live&scope=site VL - 114 ID - 489 ER - TY - JOUR AB - Pediatric chronic headache causes significant impairment to those affected and bears the risk of aggravation into adulthood. Intensive interdisciplinary pain treatment (IIPT) was found to positively affect pain-related and emotional outcomes in pediatric patients with chronic pain up to 4 years after treatment. This study was aimed at investigating the effect of IIPT on solely pediatric chronic headache patients. As part of a longitudinal observation study, n = 70 children and adolescents with chronic headache receiving IIPT were included, of which n = 47 completed the assessment at four assessment time points: before treatment (PRE) and at three follow-ups (6-MONTH FOLLOW-UP, 1-YEAR FOLLOW-UP, and 4-YEAR FOLLOW-UP). Pain-related (pain intensity, pain-related disability, school absence), as well as psychological outcome domains (anxiety, depression), were investigated. The results support the short-term and long-term efficacy of IIPT for pediatric chronic headache patients regarding the pain-related outcome measures by significant reductions from PRE to all follow-up measure points. For anxiety and depression, only short-term improvements were found. Future studies should specifically focus on the identification of methods to consolidate the beneficial short-term effects of IIPT on psychological outcome domains in the long term. AD - German Paediatric Pain Centre, Children’s and Adolescents’ Hospital, 45711 Datteln, Germany. Department of Children’s Pain Therapy and Paediatric Palliative Care, Faculty of Health, School of Medicine, Witten/Herdecke University, 58448 Witten, Germany. AU - Dogan, Meltem AU - Zernikow, Boris AU - Wager, Julia DB - cin20 DO - 10.3390/children8030220 DP - EBSCOhost IS - 3 N1 - Accession Number: 149559923. Language: English. Entry Date: In Process. Revision Date: 20210402. Publication Type: Article. PY - 2021 SN - 2227-9067 SP - 1-10 ST - Short-Term and Long-Term Effectiveness of Intensive Interdisciplinary Pain Treatment for Children and Adolescents with Chronic Headache: A Longitudinal Observation Study T2 - Children TI - Short-Term and Long-Term Effectiveness of Intensive Interdisciplinary Pain Treatment for Children and Adolescents with Chronic Headache: A Longitudinal Observation Study UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=149559923&site=ehost-live&scope=site VL - 8 ID - 143 ER - TY - JOUR AB - Aim: To identify and assess available evidence from qualitative studies exploring experiences of individuals living with fetal alcohol spectrum disorders (FASD) or those living with a child with FASD, as well as experiences of interventions aimed at supporting individuals with FASD and their families.Method: A systematic literature search was conducted in six electronic databases: PubMed, Embase, Cochrane Library, CINAHL, PsycINFO, and Scopus. Included studies were analysed using manifest content analysis. Methodological limitations and confidence in the evidence were assessed using a modified version of the Critical Appraisal Skills Programme and the Grading of Recommendations, Assessment, Development and Evaluation-Confidence in the Evidence from Reviews of Qualitative Research approach respectively.Results: Findings from 18 studies show that individuals with FASD experience a variation of disabilities, ranging from somatic problems, high pain tolerance, destructive behaviour, hyperactivity, and aggressiveness, to social problems with friendship, school attendance, and maintenance of steady employment. Most studies reported parents' experiences with FASD; parenting was viewed as a lifelong engagement and that the whole family is isolated and burdened because of FASD. People with FASD feel that their difficulties affect their daily life in a limiting way and make them feel different from others.Interpretation: From the perspective of primarily parents, individuals with FASD and their parents face many different difficulties, for which they need societal support.What This Paper Adds: Individuals with fetal alcohol spectrum disorders (FASD) feel their difficulties make them different from others. Parents think of their parenting as a lifelong engagement. There is a shortage of studies investigating experiences of children with FASD. There is a shortage of studies investigating experiences of interventions given to individuals with FASD. Resumen: Experiencias de vivir con trastornos del espectro alcoholico fetal: Una revision sistemática y una síntesis de datos cualitativos: Objetivo: Identificar y evaluar la evidencia disponible de estudios cualitativos que exploran las experiencias de individuos que viven con trastornos del espectro alcohólico fetal (TEAF) o de aquellos quienes viven con un niño con TEAF, así como experiencias de intervenciones que apuntan a apoyar individuos con TEAF y sus familias. Método: Se realizó una búsqueda sistemática de literatura en seis bases de datos electrónicas: PubMed, Embase, biblioteca Cochrane, CINAHL, PsycINFO y Scopus. Los estudios incluidos fueron analizados utilizando análisis de contenido manifiesto. Se evaluaron las limitaciones metodológicas y la confiabilidad de la evidencia utilizando una versión modificada del Programa de Habilidades de Lectura Crítica (CASP) y la fuerza de Recomendación, Evaluación, Desarrollo y Evaluación (GRADE) – Confianza en la Evidencia de Revisiones de Investigación Cualitativa (CERQual), respectivamente. Resultados: Hallazgos tomados de 18 estudios muestran que los individuos con TEAF experimentan una variedad de discapacidades, desde problemas somáticos, alta tolerancia al dolor, conductas destructivas, hiperactividad y agresividad, hasta problemas sociales con amistades, asistencia a la escuela, y mantenimiento de empleo estable. La mayoría de los estudios reportaron experiencias que los padres tenían con el TEAF; la paternidad fue vista como un compromiso de por vida y que toda la familia está aislada y con una pesada carga debido al TEAF. Personas con TEAF sienten que sus dificultades afectan sus vidas diarias de una manera limitada y les hace sentirse diferentes de los demás. Interpretación: Desde la perspectiva primariamente de los padres los individuos con TEAF y sus padres deben enfrentarse a muchas dificultades para las cuales necesitan sostén de la sociedad. Resumo: Experiências de viver com distúrbios do espectro da síndrome alcoólica fetal: uma revisão sistemática e síntese de dados qualitativos: Objetivo: Identificar e avaliar evidências disponíveis de estudos qualitativos que exploraram experiências de indivíduos com distúrbios do espectro da síndrome alcoólica fetal (DESAF) ou aqueles que vivem com uma criança com DESAF, bem como experiências de intervenções com o objetivo de apoiar indivíduos com DESAF e seus familiares. Métodos: Uma busca sistemática foi conduzida em seis bases de dados eletrônicas: PubMed, Embase, Cochrane Library, CINAHL, PsycINFO e Scopus. Os estudos incluídos foram analisados utilizando a análise de conteúdo manifesto. As limitações metodológicas e a confiança na evidência foram avaliadas utilizando uma versão modificada do “Programa de de habilidades de avaliação crítica” e da abordagem da “Pontuação de recomendações, avaliação, desenvolvimento e confiança na avaliação da evidência de revisões de pesquisa qualitativa”, respectivamente. Resultados: Os achados de 18 estudos mostraram que indivíduos com DESAF experimentam uma variedade de deficiências, que vão desde problemas somáticos, alta tolerância a dor, comportamento destrutivo, hiperatividade e agressividade, até problemas sociais com amizades, frequência escolar e manutenção de emprego estável. A maioria dos estudos relataram experiências dos pais de crianças com DESAF; a parentalidade foi vista como um compromisso pela vida toda e que toda a família é isolada e sobrecarregada por conta da DESAF. As pessoas com DESAF sentem que suas dificuldades afetam a vida diária de sua família de forma limitante a faz com que se sintam diferentes dos outros. Interpretação: Da perspectiva dos pais, indivíduos com DESAF e seus familiares enfrentam muitas dificuldades para as quais precisam de suporte social. AD - Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU), Stockholm, Sweden Department of Learning, Informatics, Management and Ethics, Karolinska Institutet, Stockholm, Sweden Norwegian Institute of Public Health Centre for the Health Services, Oslo, Norway Department of Neuroscience, Psychiatry, Uppsala University, Uppsala, Sweden AN - 130547652. Language: English. Entry Date: 20180716. Revision Date: 20190801. Publication Type: journal article AU - Domeij, Helena AU - Fahlström, Gunilla AU - Bertilsson, Göran AU - Hultcrantz, Monica AU - Munthe‐Kaas, Heather AU - Gordh, Christina Nehlin AU - Helgesson, Gert AU - Munthe-Kaas, Heather DB - cin20 DO - 10.1111/dmcn.13696 DP - EBSCOhost IS - 8 KW - Fetal Alcohol Syndrome -- Physiopathology Fetal Alcohol Syndrome -- Psychosocial Factors Fetal Alcohol Syndrome -- Nursing Bem Sex Role Inventory Human Systematic Review N1 - research; systematic review. Journal Subset: Biomedical; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. Special Interest: Evidence-Based Practice. NLM UID: 0006761. PMID: NLM29479676. PY - 2018 SN - 0012-1622 SP - 741-752 ST - Experiences of living with fetal alcohol spectrum disorders: a systematic review and synthesis of qualitative data T2 - Developmental Medicine & Child Neurology TI - Experiences of living with fetal alcohol spectrum disorders: a systematic review and synthesis of qualitative data UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=130547652&site=ehost-live&scope=site VL - 60 ID - 294 ER - TY - JOUR AB - Previous studies have demonstrated that parental cognitive, behavioral, and emotional factors are related to child functioning in children and adolescents with chronic pain. This is particularly important to understand how to potentially enhance the efficacy of psychological interventions for children by incorporating interventions targeting parents. We conducted a systematic review and meta-analysis to identify the specific parent factors that have been examined in the literature and to quantify the associations observed between parent factors and child pain and disability. A search of the electronic databases EMBASE, PsychINFO, Medline, and PubMed was conducted, using search terms related to chronic pain, pediatric population, and parents. Fifty-four studies met criteria and were included in the review. Parent pain catastrophizing and protective behavior were the most commonly assessed parental constructs in the literature. Meta-analyses were conducted for associations between parent pain catastrophizing, parent protective behaviors, parent anxiety and depression, and parent stress associated with parenting a child with chronic pain with child pain, disability, school functioning, and emotional functioning. Correlation coefficients were pooled using the random-effects model. A medium relationship was observed between higher protective behavior and poorer school functioning (r = -0.39), and small relationships were found between higher parent pain catastrophizing and increased child disability (r = 0.29); higher protective behaviors and increased child disability (r = 0.25); and increased parent depression and anxiety with increased child disability (r = 0.23 and r = 0.24, respectively). Future research is needed to investigate broader parent variables and overcome methodological weaknesses in this field. AD - Graduate School of Health, University of Technology Sydney, Ultimo, Australia Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, United States Center for Child Health, Behavior, and Development, Seattle Children's Research Institute, Seattle, WA, United States AN - 148095150. Language: English. Entry Date: 20201125. Revision Date: 20210116. Publication Type: journal article. Journal Subset: Biomedical AU - Donnelly, Theresa J. AU - Palermo, Tonya M. AU - Newton-John, Toby R. O. DB - cin20 DO - 10.1097/j.pain.0000000000001833 DP - EBSCOhost IS - 7 N1 - Continental Europe; Europe; Peer Reviewed. NLM UID: 7508686. PMID: NLM32132395. PY - 2020 SN - 0304-3959 SP - 1401-1419 ST - Parent cognitive, behavioural, and affective factors and their relation to child pain and functioning in pediatric chronic pain: a systematic review and meta-analysis T2 - PAIN TI - Parent cognitive, behavioural, and affective factors and their relation to child pain and functioning in pediatric chronic pain: a systematic review and meta-analysis UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=148095150&site=ehost-live&scope=site VL - 161 ID - 181 ER - TY - JOUR AB - Abstract: Migraines dramatically affect adolescents' quality of life. One area of particular importance is the impact of migraines on adolescents' social functioning. To understand the impact of migraines on adolescents' social functioning from multiple informants, we performed semistructured interviews with adolescents who have migraines, their caregivers, and clinicians who treat adolescents who have migraines. Three major themes related to social functioning were identified from the adolescent interviews: The need to be alone; lack of support from siblings; and the feeling of not being understood by others. The caregiver interviews yielded three main themes related to family functioning: that plans can change quickly; that family life revolves around helping the child with the migraine; and parents' feelings of inadequacy in helping their child. There were two main themes derived from the clinician interviews related to perception of family functioning: the importance of parental involvement; and the role of adolescents' school and social lives in migraine prevention. There are a number of unmet needs among adolescents with recurrent migraine and their families. Interviews with adolescents, caregivers, and clinicians suggest a number of areas for intervention. AD - Inflexxion Inc., Newton, Massachusetts Department of Pediatrics, David Geffen School of Medicine, University of California, Los Angeles, California AN - 104124116. Language: English. Entry Date: 20140601. Revision Date: 20200708. Publication Type: Journal Article AU - Donovan, Elizabeth AU - Mehringer, Stacey AU - Zeltzer, Lonnie K. DB - cin20 DO - 10.1016/j.pmn.2011.09.002 DP - EBSCOhost IS - 4 KW - Migraine -- Prevention and Control -- In Adolescence Caregivers Social Behavior -- In Adolescence Human Qualitative Studies Semi-Structured Interview Thematic Analysis Family Functioning Parental Role Attitude to Illness Adolescence N1 - research. Journal Subset: Blind Peer Reviewed; Core Nursing; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Pain and Pain Management. NLM UID: 100890606. PMID: NLM24315265. PY - 2013 SN - 1524-9042 SP - e135-41 ST - A Qualitative Analysis of Adolescent, Caregiver, and Clinician Perceptions of the Impact of Migraines on Adolescents' Social Functioning T2 - Pain Management Nursing TI - A Qualitative Analysis of Adolescent, Caregiver, and Clinician Perceptions of the Impact of Migraines on Adolescents' Social Functioning UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104124116&site=ehost-live&scope=site VL - 14 ID - 506 ER - TY - JOUR AB - Background: The study was performed to examine the hypothesis that functional outcomes following major lower-extremity trauma sustained in the military would be similar between patients treated with amputation and those who underwent limb salvage.Methods: This is a retrospective cohort study of 324 service members deployed to Afghanistan or Iraq who sustained a lower-limb injury requiring either amputation or limb salvage involving revascularization, bone graft/bone transport, local/free flap coverage, repair of a major nerve injury, or a complete compartment injury/compartment syndrome. The Short Musculoskeletal Function Assessment (SMFA) questionnaire was used to measure overall function. Standard instruments were used to measure depression (the Center for Epidemiologic Studies Depression Scale), posttraumatic stress disorder (PTSD Checklist-military version), chronic pain (Chronic Pain Grade Scale), and engagement in sports and leisure activities (Paffenbarger Physical Activity Questionnaire). The outcomes of amputation and salvage were compared by using regression analysis with adjustment for age, time until the interview, military rank, upper-limb and bilateral injuries, social support, and intensity of combat experiences.Results: Overall response rates were modest (59.2%) and significantly different between those who underwent amputation (64.5%) and those treated with limb salvage (55.4%) (p = 0.02). In all SMFA domains except arm/hand function, the patients scored significantly worse than population norms. Also, 38.3% screened positive for depressive symptoms and 17.9%, for posttraumatic stress disorder (PTSD). One-third (34.0%) were not working, on active duty, or in school. After adjustment for covariates, participants with an amputation had better scores in all SMFA domains compared with those whose limbs had been salvaged (p < 0.01). They also had a lower likelihood of PTSD and a higher likelihood of being engaged in vigorous sports. There were no significant differences between the groups with regard to the percentage of patients with depressive symptoms, pain interfering with daily activities (pain interference), or work/school status.Conclusions: Major lower-limb trauma sustained in the military results in significant disability. Service members who undergo amputation appear to have better functional outcomes than those who undergo limb salvage. Caution is needed in interpreting these results as there was a potential for selection bias. AD - Walter Reed National Military Medical Center,Washington, DC, USA AN - 108018998. Language: English. Entry Date: 20130322. Revision Date: 20160517. Publication Type: journal article AU - Doukas, C. R. AU - Hayda, C. R. AU - Frisch, H. M. AU - Andersen, C. R. AU - Mazurek, C. M. AU - Ficke, C. J. AU - Keeling, C. J. AU - Pasquina, C. P. AU - Wain, H. J. AU - Carlini, A. R. AU - Mackenzie, E. J. AU - Doukas, William C. AU - Hayda, Roman A. AU - Frisch, H. Michael AU - Andersen, Romney C. AU - Mazurek, Michael T. AU - Ficke, James R. AU - Keeling, John J. AU - Pasquina, Paul F. AU - Wain, Harold J. DB - cin20 DO - 10.2106/JBJS.K.00734 DP - EBSCOhost IS - 2 KW - Amputation Arm Injuries -- Surgery Leg Injuries -- Surgery Limb Salvage Military Medicine Adolescence Adult Arm Injuries -- Epidemiology Arm Injuries -- Psychosocial Factors Center for Epidemiological Studies Depression Scale Chronic Disease Clinical Assessment Tools Depression -- Epidemiology Disability Evaluation Female Human Leg Injuries Leg Injuries -- Epidemiology Male Pain Measurement Psychological Tests Questionnaires Recovery Regression Retrospective Design Scales Stress Disorders, Post-Traumatic Treatment Outcomes United States N1 - research. Commentary: Pinzur MS, Pinzur Michael S. The dark side of amputation rehabilitation: commentary on an article by COL (Ret) William C. Doukas, MD, et al.: "The Military Extremity Trauma Amputation/Limb Salvage (METALS) study. outcomes of amputation versus limb salvage following major... (J BONE JOINT SURG (AM)) 1/16/2013; 95 (2): e121-2. Journal Subset: Biomedical; Blind Peer Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Perioperative Care. Instrumentation: Paffenbarger Physical Activity Questionnaire; Center for Epidemiologic Studies Depression Scale (CES-D); PTSD Checklist-Military Version; Short Musculoskeletal Function Assessment (SMFA); Chronic Pain Grade Scale. NLM UID: 0014030. PMID: NLM23324961. PY - 2013 SN - 0021-9355 SP - 138-145 ST - The Military Extremity Trauma Amputation/Limb Salvage (METALS) study: outcomes of amputation versus limb salvage following major lower-extremity trauma T2 - Journal of Bone & Joint Surgery, American Volume TI - The Military Extremity Trauma Amputation/Limb Salvage (METALS) study: outcomes of amputation versus limb salvage following major lower-extremity trauma UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=108018998&site=ehost-live&scope=site VL - 95 ID - 537 ER - TY - JOUR AB - OBJECTIVE. The goal was to examine whether being a victim of bullying was associated with medicine use, taking into account the increased prevalence of physical and psychological symptoms. METHODS. The study population included all students in grades 5, 7, and 9 (mean ages: 11.6, 13.6, and 15.6 years, respectively) in a random sample of schools in Denmark (participation rate: 88.5%; N = 5205). The students reported health problems, medicine use, bullying, and a range of psychosocial conditions in an anonymous standardized questionnaire. The outcome measure was self-reported medicine use for headache, stomachache, difficulties in getting to sleep, and nervousness. The determinant was frequency of exposure to bullying, measured with 1 item. RESULTS. In multivariate models adjusted for age and social class, we found that adolescent victims of bullying used medicine for pains and psychological problems more often than did adolescents who were not bullied. The increased odds of using medicine were not explained by the higher prevalence of symptoms among the bullied children. CONCLUSIONS. We found victimization from bullying to be associated with medicine use, even when we controlled for the higher prevalence of symptoms among bullied victims. The medications that adolescents use can have adverse effects, in addition to the potentially health-damaging effects of bullying. Policy makers, health care professionals, and school staff should be aware that the adolescent victims of bullying are prone to excess use of medicine, and preventive actions should be taken to decrease the level of bullying as well as the use of medicine among adolescents. AD - Department of Social Medicine, Institute of Public Health, Faculty of Health Sciences, University of Copenhagen, Øster Farimagsgade 5, PO Box 2099, DK-1014 Copenhagen, Denmark. p.due@pubhealth.ku.dk. AN - 106158813. Language: English. Entry Date: 20070921. Revision Date: 20200708. Publication Type: Journal Article AU - Due, P. AU - Hansen, E. H. AU - Merlo, J. AU - Andersen, A. AU - Holstein, B. E. DB - cin20 DO - 10.1542/peds.2006-1481 DP - EBSCOhost IS - 1 KW - Bullying -- Psychosocial Factors Psychophysiologic Disorders -- Drug Therapy Victims Abdominal Pain -- Drug Therapy Abdominal Pain -- Psychosocial Factors Adolescence Adolescent Behavior Adolescent Psychology Anxiety -- Drug Therapy Anxiety -- Psychosocial Factors Child Confidence Intervals Cross Sectional Studies Data Analysis Software Dyssomnias -- Drug Therapy Dyssomnias -- Psychosocial Factors Female Funding Source Headache -- Drug Therapy Headache -- Psychosocial Factors Logistic Regression Male Multivariate Analysis Odds Ratio Psychophysiologic Disorders -- Etiology Questionnaires Human N1 - research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Instrumentation: Symptom Checklist (SCL) (Derogatis). Grant Information: Health Insurance Foundation and the 1991 Pharmacy Foundation. NLM UID: 0376422. PMID: NLM17606568. PY - 2007 SN - 0031-4005 SP - 110-117 ST - Is victimization from bullying associated with medicine use among adolescents? A nationally representative cross-sectional survey in Denmark T2 - Pediatrics TI - Is victimization from bullying associated with medicine use among adolescents? A nationally representative cross-sectional survey in Denmark UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106158813&site=ehost-live&scope=site VL - 120 ID - 708 ER - TY - JOUR AB - OBJECTIVE: To assess the impact of migraine on work, family, and leisure among young women who were employed full or part time, or as a full-time student. RESEARCH DESIGN AND METHODS: This cross-sectional telephone survey with 6-month recall was conducted in Israel and eight European countries (Finland, Germany, Greece, Italy, Norway, Spain, Sweden, and The Netherlands). Random-digit dialing was used to identify study participants: women 18-35 years of age with migraine, who used medication to treat their migraine, and who were employed or full-time students. RESULTS: Of 1810 participants, 42% self-reported having a physician diagnosis of migraine. During the prior 6 months, 46% of participants missed at least 1 day of work or school and 74% were prevented from functioning fully at work or school because of migraine. Mean work/school absenteeism due to migraine was 1.9 days over 6 months (range, 0.8 days in Sweden to 2.8 days in Norway). Over half of participants reported one or more occurrences of being unable to spend time with family or friends (62%) or being unable to enjoy recreational or leisure activities (67%) because of migraine. The percentage of study participants using triptans was lowest in southern Europe and highest in the Nordic countries, ranging from 1% in Greece to 50% in Sweden. Country, age, marital status, physician diagnosis of migraine, and number of migraines or severe headaches in the prior year were independent predictors of the mean number of days of migraine-related work loss. Migraine-related work loss was lowest in Sweden and greatest in Greece, Israel, and The Netherlands. Higher work loss was recorded for those 18-24 years of age; those who were separated, widowed, or divorced; those with migraine diagnosed by a physician; and those with more frequent migraines or severe headaches (> or =24/year). The 6-month recall period used when estimating patient-reported work loss, and identifying participants with migraine based on self-reported migraine or severe headache, were the most important limitations of the study. CONCLUSIONS: We found substantial migraine-related impairment of productivity at work and school as well as of family and leisure time among young women in Israel and eight European countries. AD - Sandvika Neurologic Service, Sandvika, Norway AN - 106570871. Language: English. Entry Date: 20050128. Revision Date: 20150711. Publication Type: Journal Article AU - Dueland, A. N. AU - Leira, R. AU - Burke, T. A. AU - Hillyer, E. V. AU - Bolge, S. DB - cin20 DP - EBSCOhost IS - 10 KW - Family Leisure Activities Migraine -- Psychosocial Factors Work Adolescence Adult Chi Square Test Confidence Intervals Cross Sectional Studies Data Analysis Software Descriptive Statistics Europe Funding Source Female Israel Poisson Distribution Relative Risk Telephone Human N1 - research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. Grant Information: Merck & Co., Inc.. NLM UID: 0351014. PMID: NLM15462692. PY - 2004 SN - 0300-7995 SP - 1595-1604 ST - The impact of migraine on work, family, and leisure among young women -- a multinational study T2 - Current Medical Research & Opinion TI - The impact of migraine on work, family, and leisure among young women -- a multinational study UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106570871&site=ehost-live&scope=site VL - 20 ID - 761 ER - TY - JOUR AB - Recurrent pain is a common experience in childhood and adolescence and can result in significant disability in youth, including poor quality of life, school absences, and reduced social activities. Evidence has linked adolescent risk and resilience factors with treatment outcomes. However, less research has focused on examining risk and resilience factors that may influence or predict adolescents' compliance to treatment within an interdisciplinary pediatric chronic pain management program. Participants included 64 adolescents (M= 15.00 1.69 years); 85.9% female, 84.4% Caucasian who presented to an initial evaluation in an interdisciplinary pediatric pain management program with their caregiver. Youth completed a series of questionnaires at the initial evaluation targeting pain acceptance, self-efficacy, pain catastrophizing, parental responses, pain intensity, and functional disability. Treatment compliance was measured at 3 and 6 months post-intake. Findings indicated that higher levels of adolescent-reported self-efficacy predict decreased treatment session attendance, whereas lower levels of acceptance and parental encouragement/monitoring of symptoms predict increased treatment compliance overall. Several adolescent-reported risk factors were associated with increased functional impairment among this sample. Results highlight the unique importance of risk and resilience factors within the developmental context of adolescence, while also emphasizing the need for further investigation of other relevant influences towards treatment compliance and functional impairment. AD - Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA Nemours/A.I. DuPont Hospital for Children, Wilmington, DE 19803, USA AU - Dutta, Richa Aggarwal AU - Salamon, Katherine S. DB - cin20 DO - 10.3390/children7110247 DP - EBSCOhost IS - 11 N1 - Accession Number: 147289247. Language: English. Entry Date: In Process. Revision Date: 20201205. Publication Type: Article. PY - 2020 SN - 2227-9067 SP - 1-14 ST - Risk and Resilience Factors Impacting Treatment Compliance and Functional Impairment among Adolescents Participating in an Outpatient Interdisciplinary Pediatric Chronic Pain Management Program T2 - Children TI - Risk and Resilience Factors Impacting Treatment Compliance and Functional Impairment among Adolescents Participating in an Outpatient Interdisciplinary Pediatric Chronic Pain Management Program UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=147289247&site=ehost-live&scope=site VL - 7 ID - 162 ER - TY - JOUR AB - Background: Health care providers value ready access to reliable synthesized information to support point-of-care decision making. Web-based communities, facilitated by the adoption of social media tools such as Facebook, Twitter, and YouTube, are increasingly being used for knowledge dissemination, bridging the gap between knowledge generation and synthesis and knowledge implementation.Objective: Our objective was to implement and evaluate a structured social media strategy, using multiple platforms, to disseminate Cochrane Child Health evidence to health care providers caring for children.Methods: Our social media strategy had three components: daily "tweets" using the Cochrane Child Health Twitter account, weekly WordPress blog posts, and a monthly journal club on Twitter ("tweet chat"). Each tweet, blog, and journal club shared Cochrane evidence on a child health topic. We evaluated the strategy through (1) Twitter and blog site analytics, (2) traceable link (Bitly) statistics, (3) Altmetric.com scores for promoted evidence, and (4) participant feedback. We also tracked the resources required to write the blog, tweet content, and manage the strategy.Results: The 22-week social media strategy ran between November 2014 and April 2015. We created 25 blog posts, sent 585 tweets, and hosted 3 tweet chats. Monthly blog visits and views and Twitter account followers increased over time. During the study period, the blog received 2555 visitors and 3967 page views from a geographically diverse audience of health care providers, academics, and health care organizations. In total, 183 traceable Bitly links received 3463 clicks, and the Twitter account gained 469 new followers. The most visited and viewed blog posts included gastrointestinal topics (lactose avoidance), research on respiratory conditions (honey for cough and treatments for asthma), and maternal newborn care (skin-to-skin contact). On Twitter, popular topics were related to public health (vaccination) and pain management. We collected Altmetric.com scores for 61 studies promoted during the study period and recorded an average increase of 11 points. Research staff (n=3) contributed approximately 433 hours to promotion activities and planning (6.5 hours each per week) to implement the social media strategy, and study investigators reviewed all content (blog posts and tweets).Conclusions: This study provides empirical evidence on the use of a coordinated social media strategy for the dissemination of evidence to professionals providing health services to children and youth. The results and lessons learned from our study provide guidance for future knowledge dissemination activities using social media tools. AD - Alberta Research Centre for Health Evidence, University of Alberta, Edmonton, AB, Canada Department of Pediatrics, University of Alberta, Edmonton, AB, Canada Cochrane Child Health, University of Alberta, Edmonton, AB, Canada Faculty of Medicine, Universidade de Lisboa, Lisbon, Portugal Cochrane Portugal, Universidade de Lisboa, Lisbon, Portugal AN - 125517687. Language: English. Entry Date: 20180220. Revision Date: 20181126. Publication Type: journal article AU - Dyson, Michele P. AU - Shave, Kassi AU - Wingert, Aireen AU - Featherstone, Robin M. AU - Hartling, Lisa AU - Newton, Amanda S. AU - Thomson, Denise AU - Fernandes, Ricardo M. DB - cin20 DO - 10.2196/jmir.7819 DP - EBSCOhost IS - 9 KW - Social Media -- Utilization Attitude to Health Evaluation Research Child Human N1 - research; tables/charts. Journal Subset: Biomedical; Canada; Computer/Information Science; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed. NLM UID: 100959882. PMID: NLM28864427. PY - 2017 SN - 1438-8871 SP - 19-19 ST - Social Media for the Dissemination of Cochrane Child Health Evidence: Evaluation Study T2 - Journal of Medical Internet Research TI - Social Media for the Dissemination of Cochrane Child Health Evidence: Evaluation Study UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=125517687&site=ehost-live&scope=site VL - 19 ID - 350 ER - TY - JOUR AB - Sickle cell disorder (SCD) is a chronic illness that in England disproportionately affects marginalized ethnic groups, but has yet to feature extensively within educational or disability research. This review of existing literature makes the case for a sustained developmental research programme around SCD, disability and education. There are potentially life-saving decisions that could be made by teachers in caring for a child with SCD. The place of the school as a venue for health screening with respect to vision, hearing and dental care is also complicated by SCD. The lack of a formal school policy to address the combined episodic and longer term school absences correlated with SCD clearly disadvantages a group of pupils whose academic potential may already have been curtailed by teacher expectations based on their ethnicity. Both the physical and social milieu of the school could be adapted so that the environmental triggers of severe painful episodes associated with SCD are greatly reduced. Systems of pastoral care and health education elements of the school curriculum need to be attuned to the challenges and opportunities for learning that SCD raises. SCD may be considered as a resource for education across a range of national curriculum subjects, could bring an anti-racist dimension to subjects such as mathematics, biology, history and geography and could challenge a number of prevailing disabling and racist discourses in wider society. In short, SCD could be one bridge to more inclusive education for pupils of marginalized ethnic groups. AD - De Montfort University, Leicester, UK AN - 105914740. Language: English. Entry Date: 20080516. Revision Date: 20200708. Publication Type: Journal Article AU - Dyson, S. M. AU - Atkin, K. AU - Culley, L. A. AU - Dyson, S. E. DB - cin20 DO - 10.1080/09687590701560196 DP - EBSCOhost IS - 6 KW - Anemia, Sickle Cell -- Epidemiology -- In Infancy and Childhood Education -- Trends Child Racism School Health Services -- Trends School Policies United Kingdom N1 - review. Journal Subset: Allied Health; Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 9888363. PY - 2007 SN - 0968-7599 SP - 581-594 ST - The educational experiences of young people with sickle cell disorder: a commentary on the existing literature T2 - Disability & Society TI - The educational experiences of young people with sickle cell disorder: a commentary on the existing literature UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105914740&site=ehost-live&scope=site VL - 22 ID - 699 ER - TY - JOUR AB - Painful episodes have been identified as one of the most frequent manifestations of sickle cell anemia (hemoglobin HbSS). This retrospective study compared the frequency of hospitalization and the academic performance of two groups of children with HbSS (ages 8 to 18 years) with differing frequencies of pain. A high frequency (HF) group (n = 10) was composed of children who had four or more hospitalizations for pain in the study period; those in the low frequency (LF) group (n = 11) had one or no hospitalizations for pain during the study period. The two groups were matched on age (within 6 months), gender, and ethnicity. Standardized assessments of academic achievement and school records of attendance and class grades were obtained for all participants. The standardized academic achievement for both groups was approximately one standard deviation below the normative mean of the population sample, and class grades were below a C average. School absence was frequent in both groups (LF mean = 16.8 days/year; HF mean = 35.4 days/year), and children in the HF group had significantly more absences than children in the LF group. The lack of difference in academic performance between the two groups suggests that there may be factors other than school absenteeism that affect academic achievement, which require further investigation. AD - Comprehensive Sickle Cell Disease Program, Children's Medical Center of Dallas, 1935 Motor Street, Dallas, TX 75235 AN - 107363220. Language: English. Entry Date: 19960301. Revision Date: 20170831. Publication Type: Journal Article AU - Eaton, M. L. AU - Haye, J. S. AU - Armstrong, F. D. AU - Pegelow, C. H. AU - Thomas, M. DB - cin20 DP - EBSCOhost IS - 1 KW - Anemia, Sickle Cell -- In Infancy and Childhood Absenteeism -- In Infancy and Childhood Academic Performance -- In Infancy and Childhood Readmission -- In Infancy and Childhood Pain -- In Infancy and Childhood Case Control Studies Child Adolescence Achievement Tests T-Tests Multivariate Analysis of Variance One-Way Analysis of Variance Reliability and Validity Research Instruments Human N1 - research; tables/charts. Journal Subset: Blind Peer Reviewed; Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Nursing; Peer Reviewed; USA. Instrumentation: Wide Range Achievement Test-Revised (WRAT-R)(Jastak and Wilkinson). NLM UID: 7702326. PMID: NLM8707636. PY - 1995 SN - 0146-0862 SP - 1-9 ST - Hospitalizations for painful episodes: association with school absenteeism and academic performance in children and adolescents with sickle cell anemia T2 - Issues in Comprehensive Pediatric Nursing TI - Hospitalizations for painful episodes: association with school absenteeism and academic performance in children and adolescents with sickle cell anemia UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=107363220&site=ehost-live&scope=site VL - 18 ID - 852 ER - TY - JOUR AB - Aim: To determine the effectiveness of an interdisciplinary cognitive behavioural treatment for adolescents with chronic pain.Methods: Fifty seven adolescents (mean age 14.28 years) with chronic pain and 57 accompanying adults underwent an interdisciplinary three week residential programme of group cognitive behavioural therapy. Mean chronicity of pain was 4.02 years; 75% were absent from full time education (mean absence 17 months).Results: Post-treatment adolescents reported significant improvements for self report of disability (mean difference 3.37 (95% CI 0.65 to 6.09)), physical function (mean difference timed walk of 2.61 seconds (1.02 to 4.2) and sit to stand of 3.22 per minute (0.79 to 5.65)). At three months post-treatment adolescents maintained physical improvements and reduced anxiety (mean difference 1.7 (0.72 to 2.67)), disability (mean difference 4.3 (1.44 to 7.17)), and somatic awareness (mean difference 4.43 (1.53 to 7.33)). Following treatment adults reported significant improvement in their report of adolescent disability (mean difference 4.43 (2.17 to 6.7)), adult anxiety (mean difference 1.73 (0.54 to 2.92)), depression (mean difference 1.16 (0.34 to 1.98)), and parental stress (mean difference 10.81 (2.91 to 18.78)). At three months significant improvements were maintained. At three months 64% improved school attendance; 40% had returned to full time education.Conclusions: Interdisciplinary cognitive behavioural pain management (with family involvement) is a promising approach to the management of pain, pain related distress, and disability. AD - Pain Management Unit, University of Bath and The Royal National Hospital for Rheumatic Diseases, Bath, UK Pain Management Unit, University of Bath, Bath BA2 7AY, UK; c.eccleston@bath.ac.uk AN - 106718293. Language: English. Entry Date: 20040402. Revision Date: 20200708. Publication Type: journal article AU - Eccleston, C. AU - Malleson, P. N. AU - Clinch, J. AU - Connell, H. AU - Sourbut, C. AU - Eccleston, C. AU - Malleson, P. N. AU - Clinch, J. AU - Connell, H. AU - Sourbut, C. DB - cin20 DO - 10.1136/adc.88.10.881 DP - EBSCOhost IS - 10 KW - Chronic Pain -- Rehabilitation -- In Adolescence Cognitive Therapy -- In Adolescence Residential Care -- In Adolescence Adolescence Chi Square Test Confidence Intervals Convenience Sample Family Therapy Female Inpatients Male Parental Attitudes -- Evaluation Patient Attitudes -- Evaluation Pretest-Posttest Design Psychological Tests T-Tests United Kingdom Visual Analog Scaling Human N1 - research; tables/charts. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Instrumentation: Children's Depression Inventory (CDI) (Kovacs and Beck); Modified Somatic Perception Questionnaire (MSPQ); Parenting Stress Index (PSI); Hospital Anxiety and Depression Scale (HADS); Functional Disability Inventory (FDI); Spence Children's Anxiety Scale (SCAS); Pain Coping Questionnaire (PCQ). NLM UID: 0372434. PMID: NLM14500306. PY - 2003 SN - 0003-9888 SP - 881-885 ST - Chronic pain in adolescents: evaluation of a programme of interdisciplinary cognitive behaviour therapy T2 - Archives of Disease in Childhood TI - Chronic pain in adolescents: evaluation of a programme of interdisciplinary cognitive behaviour therapy UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106718293&site=ehost-live&scope=site VL - 88 ID - 779 ER - TY - JOUR AB - Children with cancer experience multiple symptoms at end of life (EOL) that impair their health-related quality of life. Using the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines, this integrative literature review comprehensively summarized symptom experiences of children with cancer at EOL. The Cumulative Index to Nursing and Allied Health Literature (CINAHL), PubMed, and Academic Premier were searched between January 2007 to September 2019 for articles published in English using the MeSH terms: symptom burden or distress AND children with cancer or pediatric cancer or cancer children or oncology and pediatrics AND EOL care or palliative care or death or dying or terminally ill. The inclusion criteria were the following: (a) study designs [randomized controlled trials, nonexperimental, secondary analysis (if aims were distinct from primary studies) and qualitative]; (b) participants <18 years old (died of cancer, had no realistic chance of cure, or had advanced cancer); and (c) focused on symptom experiences/burden at EOL. Exclusion criteria were nonresearch articles, systematic reviews, case studies, reports, and studies that focused on cancer survivors and/or those receiving curative therapies. Twenty-seven articles met inclusion criteria. The most prevalent symptoms—pain, fatigue, dyspnea, and loss of appetitewere associated with impairments in health-related quality of life. Children with brain tumors experienced higher symptom burden compared to those with hematologic/solid malignancies. Children who received cancer-directed therapies experienced disproportionate symptoms and were more likely to die in the intensive care unit compared with those who did not receive cancer-directed therapies. Most common location of death was home. This integrative review indicated that children with cancer were polysymptomatic at EOL. Strategies facilitating effective symptom management at EOL are needed. AD - Dana-Farber Cancer Institute, Boston, MA, USA Beth Israel Deaconess Medical Center, Boston, MA, USA University of Massachusetts Boston, Boston, MA, USA AN - 143805730. Language: English. Entry Date: 20200619. Revision Date: 20200619. Publication Type: Article AU - Eche, Ijeoma Julie AU - Eche, Ifeoma Mary AU - Aronowitz, Teri DB - cin20 DO - 10.1177/1043454220909805 DP - EBSCOhost IS - 4 KW - Childhood Neoplasms -- Therapy Childhood Neoplasms -- Symptoms Cancer Patients -- Psychosocial Factors -- In Infancy and Childhood Terminally Ill Patients -- Psychosocial Factors -- In Infancy and Childhood Quality of Life Human Systematic Review Child CINAHL Database PubMed Cancer Pain Cancer Fatigue Dyspnea Anorexia Brain Neoplasms -- Symptoms Childhood Neoplasms -- Radiotherapy Childhood Neoplasms -- Drug Therapy Hematologic Neoplasms -- Symptoms Childhood Neoplasms -- Physiopathology Childhood Neoplasms -- Mortality Hospital Mortality Intensive Care Units Home Environment N1 - research; systematic review; tables/charts. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Nursing; Peer Reviewed; USA. Special Interest: Evidence-Based Practice. NLM UID: 8917825. PY - 2020 SN - 1043-4542 SP - 284-295 ST - An Integrative Review of Factors Associated With Symptom Burden at the End of Life in Children With Cancer T2 - Journal of Pediatric Oncology Nursing TI - An Integrative Review of Factors Associated With Symptom Burden at the End of Life in Children With Cancer UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=143805730&site=ehost-live&scope=site VL - 37 ID - 180 ER - TY - JOUR AB - Loin pain hematuria is characterized by chronic loin pain, hematuria, and dysuria. There are no known effective treatments for loin pain hematuria and longer term use of analgesics and surgical options are often ineffective or associated with negative side effects. This article reports on a 17-year-old female patient diagnosed with loin pain hematuria who presented with unilateral, uncontrolled loin pain following numerous unsuccessful attempts at controlling her symptoms with traditional medical interventions, including antibiotics, opioids, and renal denervation. The patient received 8 sessions of hypnotherapy. Baseline, endpoint, and follow-up measures administered included the General Health Questionnaire, Hospital Anxiety and Depression Scale, McGill Pain Questionnaire, Pain Discomfort Scale, and visual analogue measures of pain, academic interference, and social interference. At follow-up, results indicated clinically significant decreases in pain, anxiety, and depression with nearly complete remission of presenting symptoms. AD - Baylor University, USA AN - 104600149. Language: English. Entry Date: 20120320. Revision Date: 20200708. Publication Type: Journal Article AU - Elkins, Gary R. AU - Koep, Lauren L. AU - Kendrick, Cassie E. DB - cin20 DO - 10.1080/00207144.2011.622215 DP - EBSCOhost IS - 1 KW - Hypnosis -- Methods Hematuria -- Complications Chronic Pain -- Therapy Female Adolescence Chronic Pain -- Drug Therapy McGill Pain Questionnaire Questionnaires Scales Psychological Tests Visual Analog Scaling Treatment Outcomes Human N1 - case study; research; tables/charts. Journal Subset: Alternative/Complementary Therapies; Peer Reviewed; USA. Special Interest: Pain and Pain Management. Instrumentation: McGill Pain Questionnaire; Hospital Anxiety and Depression Scale (HADS); General Health Questionnaire (GHQ28); Pain Discomfort Scale. NLM UID: 0376166. PMID: NLM22098573. PY - 2012 SN - 0020-7144 SP - 111-120 ST - Hypnotherapy Intervention for Loin Pain Hematuria: A Case Study T2 - International Journal of Clinical & Experimental Hypnosis TI - Hypnotherapy Intervention for Loin Pain Hematuria: A Case Study UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104600149&site=ehost-live&scope=site VL - 60 ID - 568 ER - TY - JOUR AB - Objective: Clinicians should show an awareness on the menstrual characteristics of adolescent girls which may differ from adults in some aspects. To define menstrual cycle features among high school girls residing in a city center in southeastern Turkey. Methods: A cross-sectional survey was conducted on 1256 girls attending a high school located in the city center of Elazığ, Turkey. Data from 879 girls (median age, 16.2 years; range, 13.6-19.2 years) who agreed to participate in the study and had started to menstruate were evaluated. Results: Mean age at menarche was 12.7±1.3 years (range, 8.2-17.3 years). The mean cycle duration was 28.7±4.4 days, and the mean menstrual flow lasted 5.9±1.3 days. Severe, moderate, and mild dysmenorrhea was reported in 29%, 43%, and 28% of the girls, respectively, and 52% used analgesics for dysmenorrhea. A total of 34% of the girls defined their menstrual cycle as irregular, and 32% reported school absenteeism due to menstruation-associated complaints (pain and/or heavy bleeding). Menstrual bleeding affected attendance to classes and other school activities, daily work, social, family, and friend relationships, as well as sports/exercise activities in 43%, 49%, 58%, 48%, 44%, and 60% of the participants, respectively. In total, 30% of the responders had a problem with menstruation, and 12% and 17% of these stated that they consulted a primary care physician or specialist, respectively. Conclusion: Dysmenorrhea was found to be common in adolescent Turkish girls and to affect daily life in approximately half of the girls. AD - Fırat University Faculty of Medicine, Department of Pediatrics, Division of Pediatric Endocrinology, Elazığ, Turkey Fırat University Faculty of Medicine, Department of Pediatrics, Elazığ, Turkey AN - 115879005. Language: English. Entry Date: 20160606. Revision Date: 20190708. Publication Type: Article AU - Esen, İhsan AU - Oğuz, Baran AU - Serin, Hepsen Mine DB - cin20 DO - 10.4274/jcrpe.2026 DP - EBSCOhost IS - 2 KW - Menstrual Cycle -- In Adolescence -- Turkey Human Turkey Female Adolescence Young Adult Cross Sectional Studies Schools, Secondary Age of Onset Time Factors Dysmenorrhea -- Epidemiology Analgesics -- Therapeutic Use Absenteeism Activities of Daily Living Sports Exercise Interpersonal Relations Menstruation Disorders -- Epidemiology Menstruation Disorders -- Therapy Questionnaires Data Analysis Software Descriptive Statistics Chi Square Test T-Tests P-Value Confidence Intervals N1 - research; tables/charts. Journal Subset: Biomedical. PY - 2016 SN - 1308-5727 SP - 192-196 ST - Menstrual Characteristics of Pubertal Girls: A Questionnaire-Based Study in Turkey T2 - Journal of Clinical Research in Pediatric Endocrinology TI - Menstrual Characteristics of Pubertal Girls: A Questionnaire-Based Study in Turkey UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=115879005&site=ehost-live&scope=site VL - 8 ID - 404 ER - TY - JOUR AD - Nationwide Children's Hospital, Columbus, OH AN - 123373212. Language: English. Entry Date: In Process. Revision Date: 20170605. Publication Type: Article. Supplement Title: Apr2017 Supplement. Journal Subset: Biomedical AU - Evans, J. AU - Hahn, A. AU - Hoehn, J. AU - Lemanek, K. DB - cin20 DO - 10.1016/j.jpain.2017.02.152 DP - EBSCOhost N1 - Peer Reviewed; USA. NLM UID: 100898657. PY - 2017 SN - 1526-5900 SP - S40-S41 ST - (260) Somatization, Sleep, School Attendance, and Quality of Life as Predictors of Completing a Pediatric Pain Clinic T2 - Journal of Pain TI - (260) Somatization, Sleep, School Attendance, and Quality of Life as Predictors of Completing a Pediatric Pain Clinic UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=123373212&site=ehost-live&scope=site VL - 18 ID - 366 ER - TY - JOUR AB - Introduction: Irritable bowel syndrome affects as many as 14% of high school-aged students. Symptoms include discomfort in the abdomen, along with diarrhea and/or constipation and other gastroenterological symptoms that can significantly impact quality of life and daily functioning. Emotional stress appears to exacerbate irritable bowel syndrome symptoms suggesting that mind-body interventions reducing arousal may prove beneficial. For many sufferers, symptoms can be traced to childhood and adolescence, making the early manifestation of irritable bowel syndrome important to understand. The current study will focus on young people aged 14-26 years with irritable bowel syndrome. The study will test the potential benefits of Iyengar yoga on clinical symptoms, psychospiritual functioning and visceral sensitivity. Yoga is thought to bring physical, psychological and spiritual benefits to practitioners and has been associated with reduced stress and pain. Through its focus on restoration and use of props, Iyengar yoga is especially designed to decrease arousal and promote psychospiritual resources in physically compromised individuals. An extensive and standardized teacher-training program support Iyengar yoga's reliability and safety. It is hypothesized that yoga will be feasible with less than 20% attrition; and the yoga group will demonstrate significantly improved outcomes compared to controls, with physiological and psychospiritual mechanisms contributing to improvements.Methods/design: Sixty irritable bowel syndrome patients aged 14-26 will be randomly assigned to a standardized 6-week twice weekly Iyengar yoga group-based program or a wait-list usual care control group. The groups will be compared on the primary clinical outcomes of irritable bowel syndrome symptoms, quality of life and global improvement at post-treatment and 2-month follow-up. Secondary outcomes will include visceral pain sensitivity assessed with a standardized laboratory task (water load task), functional disability and psychospiritual variables including catastrophizing, self-efficacy, mood, acceptance and mindfulness. Mechanisms of action involved in the proposed beneficial effects of yoga upon clinical outcomes will be explored, and include the mediating effects of visceral sensitivity, increased psychospiritual resources, regulated autonomic nervous system responses and regulated hormonal stress response assessed via salivary cortisol.Trial Registration: ClinicalTrials.gov NCT01107977. AD - Pediatric Pain Program, Department of Pediatrics, David Geffen School of Medicine, University of California, Los Angeles, USA. SuEvans@mednet.ucla.edu. AN - 104809352. Language: English. Entry Date: 20120831. Revision Date: 20200708. Publication Type: journal article AU - Evans, Subhadra AU - Cousins, Laura AU - Tsao, Jennie Ci AU - Sternlieb, Beth AU - Zeltzer, Lonnie K. AU - Tsao, Jennie C. I. DB - cin20 DO - 10.1186/1745-6215-12-15 DP - EBSCOhost IS - 1 KW - Irritable Bowel Syndrome -- Therapy Study Design Yoga Abdominal Pain -- Etiology Abdominal Pain -- Psychosocial Factors Abdominal Pain -- Therapy Adolescence Adult Autonomic Nervous System -- Physiopathology California Emotions Female Hydrocortisone -- Metabolism Irritable Bowel Syndrome -- Complications Irritable Bowel Syndrome -- Metabolism Irritable Bowel Syndrome -- Physiopathology Irritable Bowel Syndrome -- Psychosocial Factors Male Pain Measurement Quality of Life Questionnaires Saliva -- Metabolism Spirituality Time Factors Treatment Outcomes Young Adult N1 - research; randomized controlled trial. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Grant Information: 1K01AT005093 - 01A1/AT/NCCIH NIH HHS/United States. NLM UID: 101263253. PMID: NLM21244698. PY - 2011 SN - 1745-6215 SP - 15-15 ST - Protocol for a randomized controlled study of Iyengar yoga for youth with irritable bowel syndrome T2 - Trials TI - Protocol for a randomized controlled study of Iyengar yoga for youth with irritable bowel syndrome UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104809352&site=ehost-live&scope=site VL - 12 ID - 600 ER - TY - JOUR AB - Iyengar yoga uses postures and props to support the body so that practitioners can engage in poses that would otherwise be more difficult. This type of yoga may be useful in treating children and adolescents who have chronic pain and disability. In this case study, the authors discuss a 14-y-old girl who had two surgeries for gastro-esophageal reflux disease (GERD) and who had continued chest and abdominal pain, as well as vomiting, difficulty eating, weight loss, and anxiety. Having significantly impaired functioning, she was unable to attend school, sleep, socialize, or eat, and she had become wheelchair-bound. Despite evaluations and treatments by specialists over an extended period of time, her symptoms had not improved. This case history describes how the authors used a 4-mo treatment of Iyengar yoga to help the adolescent resume activities and re-engage with her environment. The authors intend this report to stimulate scientific study of this form of treatment for children and adolescents with chronic pain. AD - Pediatric Pain Program, Department of Pediatrics, David Geffen School of Medicine, University of California, Los Angeles, USA. suevans@mednet.ucla.edu AN - 107968051. Language: English. Entry Date: 20131108. Revision Date: 20161119. Publication Type: journal article AU - Evans, Subhadra AU - Sternlieb, Beth AU - Zeltzer, Lonnie AU - Tsao, Jennie DB - cin20 DP - EBSCOhost IS - 5 KW - Chronic Pain -- Therapy Yoga Activities of Daily Living Adolescence Chronic Pain -- Etiology Female Gastroesophageal Reflux -- Complications Treatment Outcomes Weight Gain N1 - case study. Journal Subset: Alternative/Complementary Therapies; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Grant Information: K01 AT005093/AT/NCCIH NIH HHS/United States. NLM UID: 9502013. PMID: NLM23981408. PY - 2013 SN - 1078-6791 SP - 66-70 ST - Iyengar yoga and the use of props for pediatric chronic pain: a case study T2 - Alternative Therapies in Health & Medicine TI - Iyengar yoga and the use of props for pediatric chronic pain: a case study UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=107968051&site=ehost-live&scope=site VL - 19 ID - 515 ER - TY - JOUR AB - Little is known about how sociodemographic factors relate to children's chronic pain. This paper describes the pain, health, and sociodemographic characteristics of a cohort of children presenting to an urban tertiary chronic pain clinic and documents the role of age, sex and minority status on pain-related characteristics. A multidisciplinary, tertiary clinic specializing in pediatric chronic pain. Two hundred and nineteen patients and their parents were given questionnaire packets to fill out prior to their intake appointment which included demographic information, clinical information, Child Health Questionnaire -Parent Report, Functional Disability Index -Parent Report, Child Somatization Index -Parent Report, and a Pain Intensity Scale. Additional clinical information was obtained from patients' medical records via chart review. This clinical sample exhibited compromised functioning in a number of domains, including school attendance, bodily pain, and health compared to normative data. Patients also exhibited high levels of functional disability. Minority children evidenced decreased sleep, increased somatization, higher levels of functional disability, and increased pain intensity compared to Caucasians. Caucasians were more likely to endorse headaches than minorities, and girls were more likely than boys to present with fibromyalgia. Younger children reported better functioning than did teens. The results indicate that sociodemographic factors are significantly associated with several pain-related characteristics in children with chronic pain. Further research must address potential mechanisms of these relationships and applications for treatment. AD - Pediatric Pain Program, Department of Pediatrics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America AN - 104840186. Language: English. Entry Date: 20110422. Revision Date: 20150711. Publication Type: Journal Article AU - Evans, Subhadra AU - Taub, Rebecca AU - Tsao, Jennie C. I. AU - Meldrum, Marcia AU - Zeltzer, Lonnie K. DB - cin20 DP - EBSCOhost IS - 3 KW - Aging Chronic Pain -- Therapy Minority Groups Pediatric Care Sex Factors Socioeconomic Factors Adolescence Bivariate Statistics California Chi Square Test Child Descriptive Statistics Female Funding Source Human Male Multiple Regression Multivariate Analysis Prospective Studies Questionnaires Urban Areas Visual Analog Scaling N1 - research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Instrumentation: Child Health Questionnaire (CHQ); Functional Disability Inventory (FDI); Child Somatization index. Grant Information: National Institute of Dental and Craniofacial Research and National Institute of Mental Health.. NLM UID: 101480118. PY - 2010 SN - 1939-5914 SP - 273-281 ST - Sociodemographic factors in a pediatric chronic pain clinic: the roles of age, sex and minority status in pain and health characteristics T2 - Journal of Pain Management TI - Sociodemographic factors in a pediatric chronic pain clinic: the roles of age, sex and minority status in pain and health characteristics UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104840186&site=ehost-live&scope=site VL - 3 ID - 624 ER - TY - JOUR AB - OBJECTIVE: To assess the prevalence of generalized soft tissue rheumatism (GSTR) in medical students in Izmir, Turkey. METHODS: Medical students from each grade of Medical School of Ege University, Izmir, Turkey, were evaluated by a survey and physical examination for GSTR including fibromyalgia (FM) syndrome, myofascial pain syndrome (MPS), benign joint hypermobility syndrome (BJHS), and chronic fatigue syndrome. FM Impact Questionnaire was assessed in FM diagnosed students. Short Form-36 (SF-36) was obtained from each student to determine the quality of life. RESULTS: Among the participants (n = 306), 191 were women (62.4%) and 115 were men (37.6%) and mean age was 20.23 +/- 1.56. Fifty-eight students (19%) were diagnosed with a GSTR. The distributions of the diagnoses were: 6 (2%) FM, 21 (6.9%) MPS, 28 (9.2%) BJHS, 1 (0.3%) chronic fatigue syndrome, and 2 students (0.7%) had both BJHS and MPS. Fifty-three (27.7%) women and 5 (4.3%) men were diagnosed with a GSTR (P < 0.01). Mean FM Impact Questionnaire score was 50.8 in FM diagnosed students. Physical role, vitality, and mental subscores of SF-36 were significantly lower in the students having a GSTR (P < 0.05). CONCLUSION: This is the first study performed in medical students to find out the prevalence of generalized soft tissue rheumatic conditions. Although medical students are under high stress due to hard training, the prevalence of GSTR in medical students was found similar to previous reports in the general population. AD - Ege University Medical Faculty, Department of Physical and Rehabilitation Medicine, Bornova, Izmir, Turkey. eyigor@hotmail.com AN - 105742248. Language: English. Entry Date: 20080613. Revision Date: 20210406. Publication Type: Journal Article AU - Eyigor, S. AU - Ozdedeli, S. AU - Durmaz, B. DB - cin20 DO - 10.1097/rhu.0b013e31816b1920 DP - EBSCOhost IS - 2 KW - Musculoskeletal Diseases -- Epidemiology Musculoskeletal Diseases -- Immunology Rheumatic Diseases -- Epidemiology Students, Medical -- Statistics and Numerical Data Adolescence Adult Female Male Prevalence Stress -- Epidemiology Turkey Human N1 - research. Journal Subset: Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 9518034. PMID: NLM18391672. PY - 2008 SN - 1076-1608 SP - 65-68 ST - The prevalence of generalized soft tissue rheumatic conditions in Turkish medical students T2 - JRC: Journal of Clinical Rheumatology TI - The prevalence of generalized soft tissue rheumatic conditions in Turkish medical students UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105742248&site=ehost-live&scope=site VL - 14 ID - 686 ER - TY - JOUR AB - Headache is the most frequent neurological symptom and the most prevalent pain in children and adolescents, and constitutes a serious health problem that may lead to impairment in several areas. Psychosocial factors, social environment, life events, school and family stressors are all closely related to headaches. A multidisciplinary strategy is fundamental in addressing headache in children and adolescents. Applying such a strategy can lead to reductions in frequency and severity of the pain, improving significantly the quality of life of these children. It has been demonstrated that behavioral intervention is highly effective, especially in the treatment of paediatric headache, and can enhance or replace pharmacotherapy, with the advantage of eliminating dangerous side effects and or reducing costs. Behavioral interventions appear to maximize long-term therapeutic benefits and improve compliance with pharmacological treatment, which has proven a significant problem with child and adolescent with headache. The goal of this review is to examine the existing literature on behavioral therapies used to treat headache in children and adolescents, and so provide an up-to-date picture of what behavioral therapy is and what its effectiveness is. AD - Department of Pediatrics and Child and Adolescent Neuropsychiatry , Sapienza University of Rome , Via dei Sabelli, 108 00185 Rome Italy Department of Dynamic and Clinical Psychology , Sapienza University of Rome , Rome Italy Department of Computer, Control and Management Engineering Antonio Ruberti , Sapienza University of Rome , Rome Italy Glia Institute , Ribeirão Preto Brazil AN - 117879196. Language: English. Entry Date: 20170313. Revision Date: 20190708. Publication Type: Article AU - Faedda, Noemi AU - Cerutti, Rita AU - Verdecchia, Paola AU - Migliorini, Daniele AU - Arruda, Marco AU - Guidetti, Vincenzo DB - cin20 DO - 10.1186/s10194-016-0671-4 DP - EBSCOhost IS - 1 KW - Headache -- Prevention and Control Headache -- Psychosocial Factors Pain Management -- Methods Adolescent Health Child Health Cognitive Therapy -- Methods Behavior Therapy -- Methods Patient Compliance Life Style Changes Patient Education Comorbidity Relaxation Techniques Biofeedback N1 - pictorial; review. Journal Subset: Biomedical; Continental Europe; Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. NLM UID: 100940562. PY - 2016 SN - 1129-2369 SP - 1-10 ST - Behavioral management of headache in children and adolescents T2 - Journal of Headache & Pain TI - Behavioral management of headache in children and adolescents UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=117879196&site=ehost-live&scope=site VL - 17 ID - 391 ER - TY - JOUR AB - Objective: Prior research has revealed a link between peer victimization and somatic complaints in healthy youth; however, the peer victimization experiences of youth with clinically significant chronic pain have not been examined. This study aims to determine rates of peer victimization among youth seeking treatment for chronic pain and to compare these rates to a community control group. Relationships between peer victimization, depressive symptoms, and functional disability are also examined. Method: One hundred forty-three adolescents (70 with chronic pain) completed measures assessing their experience of traditional (physical, relational, reputational) and cyber-based peer victimization, as well as measures assessing their depressive symptoms and pain-related functional disability. Results: Peer victimization experiences were common among youth with and without chronic pain. Within the chronic pain group, there were differences in rates of peer victimization as a function of the adolescent's school setting. Adolescents with chronic pain attending traditional schools reported more frequent peer victimization experiences than adolescents with pain not enrolled in school or attending online/home school. Within the chronic pain sample, peer victimization was moderately associated with depressive symptoms and functional disability. Tests of a simple mediation model revealed a significant indirect effect of peer victimization on functional disability, through depression. Conclusions: These results are the first to systematically document the peer victimization experiences of adolescents with chronic pain. Peer victimization is commonly experienced, particularly for those enrolled in traditional school settings. Associations with depressive symptoms and functional disability suggest that peer victimization may be a useful target for intervention. AN - 128403491. Language: English. Entry Date: 20180313. Revision Date: 20180313. Publication Type: Article AU - Fales, Jessica L. AU - Rice, Sean AU - Aaron, Rachel V. AU - Palermo, Tonya M. DB - cin20 DO - 10.1037/hea0000569 DP - EBSCOhost IS - 3 KW - Chronic Pain -- Therapy -- In Adolescence Help Seeking Behavior Crime Victims Depression Disability Evaluation Human Adolescence Student Attitudes N1 - research. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 8211523. PY - 2018 SN - 0278-6133 SP - 291-300 ST - Traditional and cyber-victimization among adolescents with and without chronic pain T2 - Health Psychology TI - Traditional and cyber-victimization among adolescents with and without chronic pain UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=128403491&site=ehost-live&scope=site VL - 37 ID - 315 ER - TY - JOUR AN - 105606337. Language: English. Entry Date: 20090116. Revision Date: 20150711. Publication Type: Journal Article AU - Farmer, K. DB - cin20 DP - EBSCOhost IS - 165 KW - Migraine -- In Adolescence Absenteeism Adolescence Chronic Pain Female Migraine -- Etiology N1 - case study. Journal Subset: Consumer Health; USA. NLM UID: 9890273. PY - 2008 SN - 1521-2106 SP - 6-6 ST - Kids korner. When school absences become a problem T2 - NHF Head Lines TI - Kids korner. When school absences become a problem UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105606337&site=ehost-live&scope=site ID - 672 ER - TY - JOUR AB - Recurrent headaches in children are most often migraines and are based in a genetic predisposition with a low headache threshold. As with any pain experience, there is a large emotional component associated with an attack of migraines that grows in amplitude as the headaches become more frequent and resistant to medicine, sleep, or other agents that used to work. Childhood headaches are especially complicated for 3 reasons: (1) the parents' fear (communicated to the child that serious medical pathology underlies the head pain), (2) the lack of evidence-based pharmacologic treatment, and (3) the belief that these headaches are largely psychological. This article addresses the mystery surrounding childhood headaches by delving into the influence of school, friends, and family; the impact of divorce; the coping skills required for a child to manage a migrainous nervous system; the potential secondary gain from headaches; psychiatric comorbidities and how to treat them; and the role of psychological intervention. © 2010 Elsevier Inc. All rights reserved. AD - Headache Care Center, Springfield, MO; kfarmer@primarycareed.com AN - 105043669. Language: English. Entry Date: 20100910. Revision Date: 20200708. Publication Type: Journal Article AU - Farmer, K. AU - Dunn, D. AU - Scott, E. DB - cin20 DO - 10.1016/j.spen.2010.04.002 DP - EBSCOhost IS - 2 KW - Headache -- Psychosocial Factors Absenteeism -- Evaluation Acting Out Adolescence Affect -- Evaluation Behavior Child Comorbidity Coping Divorce Female Genetics Headache -- Physiopathology Headache -- Prevention and Control Male Medical Practice, Evidence-Based -- Methods Migraine -- Diagnosis Migraine -- Physiopathology Neurology Pediatrics Psychosocial Aspects of Illness N1 - case study. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 9441351. PMID: NLM20541100. PY - 2010 SN - 1071-9091 SP - 93-99 ST - Psychological factors in childhood headaches T2 - Seminars in Pediatric Neurology TI - Psychological factors in childhood headaches UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105043669&site=ehost-live&scope=site VL - 17 ID - 628 ER - TY - JOUR AB - OBJECTIVES: A number of studies have shown that victimization from bullying behavior is associated with substantial adverse effects on physical and psychological health, but it is unclear which comes first, the victimization or the health-related symptoms. In our present study, we investigated whether victimization precedes psychosomatic and psychosocial symptoms or whether these symptoms precede victimization. DESIGN: Six-month cohort study with baseline measurements taken in the fall of 1999 and follow-up measurements in the spring of 2000. SETTING: Eighteen elementary schools in the Netherlands. PARTICIPANTS: The study included 1118 children aged 9 to 11 years, who participated by filling out a questionnaire on both occasions of data collection. OUTCOME MEASURES: A self-administered questionnaire measured victimization from bullying, as well as a wide variety of psychosocial and psychosomatic symptoms, including depression, anxiety, bedwetting, headaches, sleeping problems, abdominal pain, poor appetite, and feelings of tension or tiredness. RESULTS: Victims of bullying had significantly higher chances of developing new psychosomatic and psychosocial problems compared with children who were not bullied. In contrast, some psychosocial, but not physical, health symptoms preceded bullying victimization. Children with depressive symptoms had a significantly higher chance of being newly victimized, as did children with anxiety. CONCLUSIONS: Many psychosomatic and psychosocial health problems follow an episode of bullying victimization. These findings stress the importance for doctors and health practitioners to establish whether bullying plays a contributing role in the etiology of such symptoms. Furthermore, our results indicate that children with depressive symptoms and anxiety are at increased risk of being victimized. Because victimization could have an adverse effect on children's attempts to cope with depression or anxiety, it is important to consider teaching these children skills that could make them less vulnerable to bullying behavior. AD - Netherlands Organization of Applied Scientific Research (TNO), Quality of Life, Leiden, The Netherlands. m.fekkes@pg.tno.nl AN - 106317529. Language: English. Entry Date: 20060811. Revision Date: 20200708. Publication Type: Journal Article AU - Fekkes, M. AU - Pijpers, F. I. M. AU - Fredriks, A. M. AU - Vogels, T. AU - Verloove-Vanhorick, S. P. DB - cin20 DO - 10.1542/peds.2005-0187 DP - EBSCOhost IS - 5 KW - Bullying Health Status Psychophysiologic Disorders -- Etiology Abdominal Pain -- Etiology Anxiety -- Etiology Child Child Psychology Confidence Intervals Data Analysis Software Depression -- Etiology Descriptive Statistics Enuresis -- Etiology Female Funding Source Male Multiple Logistic Regression Netherlands Odds Ratio Prospective Studies Questionnaires Schools, Elementary T-Tests Univariate Statistics Human N1 - research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Instrumentation: Short Depression Inventory for Children; Olweus Bully/Victim Questaionnaire. Grant Information: ZorgOnderzoek Nederland (grant 22000061). NLM UID: 0376422. PMID: NLM16651310. PY - 2006 SN - 0031-4005 SP - 1568-1574 ST - Do bullied children get ill, or do ill children get bullied? A prospective cohort study on the relationship between bullying and health-related symptoms T2 - Pediatrics TI - Do bullied children get ill, or do ill children get bullied? A prospective cohort study on the relationship between bullying and health-related symptoms UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106317529&site=ehost-live&scope=site VL - 117 ID - 728 ER - TY - JOUR AB - Study Design: A prospective, repeated-measures cohort design with high school students from Montreal, Canada.Objectives: To determine whether smoking was a risk factor for the development of low back pain or other musculoskeletal pain in a cohort of adolescents.Summary Of Background Data: Smoking has been associated with low back pain in adults. Many adolescents smoke, and the prevalence of low back pain in this age group is 30%. A history of low back pain is predictive of future problems.Methods: A total of 502 students from grades 7 to 9 were assessed from 3 schools. Data were collected at 3 times: at the beginning of the study, at 6 months, and at the end of a 12-month period. Students responded to a questionnaire addressing musculoskeletal health and life-style factors, which included smoking. Measurements of height, weight, trunk and leg flexibility, and trunk strength were obtained. Low back pain occurring at a frequency of at least once a week in the past 6 months was defined as the outcome. Multivariate methods were used to model the repeated-measures dichotomous outcome as a function of smoking and other covariates.Results: Smokers experienced low back pain more than nonsmokers (odds ratio, 2.4; 95% confidence interval, 1.3-6.0). There was also a dose-response relationship between amount smoked and development of low back pain. Smokers tended to experience more upper limb or lower limb pain than nonsmokers, although this result was not significant.Conclusions: Smoking was found to increase the risk for low back pain in this cohort of adolescents. AD - GRIS, Université de Montréal, Canada SMBD Jewish General Hospital, Centre for Clinical Epidemiology, Suite A-135, 3755 Cote Ste. Catherine Rd., Montreal, Quebec H3T 1E2, Canada; e-mail: dfeldm@po-box.mcgill.ca AN - 107093291. Language: English. Entry Date: 20000301. Revision Date: 20190818. Publication Type: journal article AU - Feldman, D. E. AU - Rossignol, M. AU - Shrier, I. AU - Abenhaim, L. AU - Feldman, D. E. AU - Rossignol, M. AU - Shrier, I. AU - Abenhaim, L. DB - cin20 DP - EBSCOhost IS - 23 KW - Low Back Pain -- Epidemiology -- In Adolescence Smoking -- Complications -- In Adolescence Prospective Studies Quebec Dynamometry Psychological Tests Descriptive Statistics Logistic Regression Data Analysis, Statistical Data Analysis Software Dose-Response Relationship, Drug Odds Ratio Confidence Intervals Bias (Research) Adolescence Male Female Human N1 - research; tables/charts. Journal Subset: Allied Health; Biomedical; Peer Reviewed; USA. Instrumentation: Mental Health Index from the Short Form-36. NLM UID: 7610646. PMID: NLM10626312. PY - 1999 SN - 0362-2436 SP - 2492-2496 ST - Smoking. A risk factor for development of low back pain in adolescents T2 - Spine (03622436) TI - Smoking. A risk factor for development of low back pain in adolescents UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=107093291&site=ehost-live&scope=site VL - 24 ID - 826 ER - TY - JOUR AB - An exploratory descriptive study whose purpose was to verify oral health problems perceived by low-income pregnant women in a community of a Sao Paulo municipality, as well as their access to treatment during pregnancy. The sample consisted of 169 women who participated in the pregnant women's group in the Sao Lucas Nucleus for Women's Health Care, from August 2004 to April 2007. Results showed that the pregnant women's mean age was 23.7 years, with an age variation of 14 to 42 years, 21.8% of which were adolescent. The educational level was low, as only 16% had concluded the eighth grade, 15.3% had finished high school and 49.7% had not completed the basic education program. Only 10.6% were employed and the family income was 1.4 times the minimum wage. Regarding the perception of oral health problems, 44.9% of the sample identified some problems, such as pain (35.5%), dental cavities (27.6%) or gum bleeding (19.7%). Of the pregnant women who reported problems, only 39.4% sought professional help. Among these, 63.3% did not obtain access to treatment because they were unable to get dental appointments (70%) or due to the fact that they were pregnant (13.3%). It was therefore concluded that, at least in this community, full procedures to assist pregnant women are not being adequately provided. Some women and even some health practitioners erroneously believe that pregnancy represents an obstacle to dental treatments. Therefore, it is necessary to provide better attention from professionals in prenatal assistance regarding the importance of oral health care and its effects on both the women's and the babies' health. AD - Universidade Guarulhos, Sao Paulo, SP, Brasil AN - 105630975. Language: Portuguese. Entry Date: 20090313. Revision Date: 20150818. Publication Type: Journal Article AU - Fernandes, R. A. Q. AU - Narchi, N. Z. DB - cin20 DP - EBSCOhost IS - 2 KW - Health Services Accessibility Oral Health -- In Pregnancy -- Brazil Poverty Adolescence Adult Brazil Descriptive Research Descriptive Statistics Educational Status Exploratory Research Female Pregnancy Human N1 - research. Journal Subset: Double Blind Peer Reviewed; Editorial Board Reviewed; Mexico & Central/South America; Nursing; Peer Reviewed. PY - 2008 SN - 1676-4285 SP - 10-10 ST - Oral health of low-income pregnant women in a community of a Sao Paulo municipality: problems perceived and access to treatment T2 - Online Brazilian Journal of Nursing TI - Oral health of low-income pregnant women in a community of a Sao Paulo municipality: problems perceived and access to treatment UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105630975&site=ehost-live&scope=site VL - 7 ID - 683 ER - TY - JOUR AB - Objectives To investigate pain level and function limitation in adolescent athletes and physically active non-athletes with PFP. Design Cross-sectional study. Setting Adolescent athletes were recruited at a sport center complex. Adolescent non-athletes were recruited from upper secondary schools. Participants 108 adolescents diagnosed with PFP: 42 adolescent athletes and 66 adolescent non-athletes. Main outcome measures To evaluate the level of pain, a visual analog scale (VAS) was used and to evaluate the overall function, the Knee Outcome in Osteoarthritis Survey (KOOS) was used. Results The adolescent athletes scored significantly higher in the VAS (Mean difference = 0.97 (95% CI = 0.35; 1.60) p = 0.003) compared to adolescent non-athletes. Adolescent athletes scored lower in the KOOS - Symptoms, Pain, Knee-related quality of life and Sport and recreation dimensions - than the non-athletes, however, the minimally clinically important difference was not achieved in Pain dimension. There was no significant difference in the Activities of daily living dimension of the KOOS. Conclusions Adolescent athletes presented higher levels of pain and lower physical function status compared with physically active non-athletes. This provides an important insight to the management of PFP in adolescent athletes as worst functional status is linked with poor prognosis in patients with PFP. AD - Laboratory of Biomechanics and Motor Control (LABCOM), School of Science and Technology, São Paulo State University (UNESP), Presidente Prudente, Sao Paulo, Brazil La Trobe Sports and Exercise Medicine Research Centre (LASEM), School of Allied Health, La Trobe University, Bundoora, Victoria, Australia AN - 131403121. Language: English. Entry Date: 20180830. Revision Date: 20180830. Publication Type: Article AU - Ferreira, Amanda Schenatto AU - de Oliveira Silva, Danilo AU - Priore, Liliam Barbuglio Del AU - Garcia, Carmen Lucia Gomes AU - Ducatti, Matheus Henrique Maiolini AU - Botta, Ana Flavia Balotari AU - Waiteman, Marina Cabral AU - de Azevedo, Fábio Mícolis DB - cin20 DO - 10.1016/j.ptsp.2018.07.005 DP - EBSCOhost KW - Physical Activity Patellofemoral Pain Syndrome Pain Functional Assessment Human Adolescence Athletes Cross Sectional Studies Surveys Questionnaires Scales Quality of Life N1 - research. Journal Subset: Allied Health; Europe; Peer Reviewed; UK & Ireland. Instrumentation: Visual Analog Scale (VAS); Knee Outcome in Osteoarthritis Survey (KOOS). NLM UID: 100940513. PY - 2018 SN - 1466-853X SP - 70-75 ST - Differences in pain and function between adolescent athletes and physically active non-athletes with patellofemoral pain T2 - Physical Therapy in Sport TI - Differences in pain and function between adolescent athletes and physically active non-athletes with patellofemoral pain UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=131403121&site=ehost-live&scope=site VL - 33 ID - 293 ER - TY - JOUR AB - BACKGROUND: The psychosocial impact of headache combined with other pains has previously been insufficiently investigated. OBJECTIVE: The present study examined the prevalence of headache, its comorbidity with other pains and psychosocial impact among adolescents. METHODS: 793 adolescents in a sample recruited from 8 schools in the middle of Sweden were assessed. RESULTS: Forty-five percent of the adolescents reported ongoing pain during assessment and more than half of the adolescents reported at least one frequent pain during the previous 6 months. The most common pain among girls was headache (42%), but for boys muscle pain (32%) was most prevalent. Number of pains and perceived pain disability were also higher among girls than boys. One-third of the headache sufferers had headache only, while one-third reported one other frequent pain and the others had at least two other frequent pains. Overall, adolescents with frequent headaches had higher levels of anxiety or depressive symptoms, in addition to functional disability and usage of analgesic medication. Frequent headache sufferers reported more problems in everyday life areas than those with infrequent headaches. CONCLUSIONS: It is recommended that adolescents suffering from recurrent headaches routinely should be asked about the presence of other pains, anxiety and depressive symptoms, medication usage, in addition to psychosocial consequences in their everyday life activities. Longitudinal research is also needed to delineate causal relationships between psychosocial factors and recurrent pains, in particular regarding possible sex differences. AN - 106812858. Language: English. Entry Date: 20070101. Revision Date: 20200708. Publication Type: Journal Article AU - Fichtel, Å AU - Larsson, B. DB - cin20 DO - 10.1046/j.1526-4610.2002.02178.x DP - EBSCOhost IS - 8 KW - Pain -- Psychosocial Factors -- In Adolescence Pain -- Epidemiology -- In Adolescence Comorbidity -- In Adolescence Sweden Center for Epidemiological Studies Depression Scale Research Instruments Descriptive Statistics P-Value Analysis of Variance T-Tests Kruskal-Wallis Test Chi Square Test Pearson's Correlation Coefficient Sex Factors Headache -- Psychosocial Factors -- In Adolescence Headache -- Epidemiology -- In Adolescence Two-Way Analysis of Variance Absenteeism -- In Adolescence Functional Status -- In Adolescence Adolescence Male Female Human N1 - research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. Instrumentation: Center for Epidemiologic Studies Depression Scale (CES-D); Revised Children's Manifest Anxiety Scale (RCMAS); Illness Behavior Encouragement Scale (IBES); Functional Disability Inventory (FDI) (Walker and Greene). NLM UID: 2985091R. PMID: NLM12390639. PY - 2002 SN - 0017-8748 SP - 766-775 ST - Psychosocial impact of headache and comorbidity with other pains among Swedish school adolescents T2 - Headache: The Journal of Head & Face Pain TI - Psychosocial impact of headache and comorbidity with other pains among Swedish school adolescents UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106812858&site=ehost-live&scope=site VL - 42 ID - 794 ER - TY - JOUR AB - Purpose: Approximately one third of adolescents in the United States report experiencing frequent headaches and stomachaches. We examined the association of psychosocial and physical factors with the report of weekly headaches or stomachaches using a representative sample of US teens.Methods: Data for this project are from the survey of Health Behavior in School-Aged Children (HBSC), 2005-2006, a nationally representative sample of students in grades 6-10 in the United States. The total sample includes 12,070 students aged 11-17. Using logistic regression we modeled chronic headache and stomachache separately with the same set of physical predictors (dieting and substance use habits) and psychosocial predictors (attitudes towards self-image, peers, and family) along with demographic controls.Results: Almost 20% of respondents experienced headaches weekly, and 12% experienced abdominal pain. Both physical and psychosocial factors were predictive of chronic symptoms. Increased substance usage and unhealthy eating practices were associated with the likelihood of experiencing both headaches and stomachaches. Negative self-image, family relationships, and school life were also predictive of symptom frequency.Conclusion: Headaches and stomachaches are associated with poor eating and substance use habits, as well as problems with self-image or social relationships among adolescents. For health care professionals, a holistic approach is needed to effectively address symptoms and prevent long-term health problems. AD - Department of Sociology, Brigham Young University, Provo, UT, United States of America AN - 130313845. Language: English. Entry Date: In Process. Revision Date: 20180627. Publication Type: journal article. Journal Subset: Biomedical AU - Fife, Benjamin AU - Forste, Renata DB - cin20 DO - 10.1515/ijamh-2016-0062 DP - EBSCOhost IS - 3 N1 - Middle East; Peer Reviewed. NLM UID: 8506960. PMID: NLM27665418. PY - 2018 SN - 0334-0139 SP - N.PAG-N.PAG ST - Physical and social factors associated with early adolescent headache and stomachache pain T2 - International Journal of Adolescent Medicine & Health TI - Physical and social factors associated with early adolescent headache and stomachache pain UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=130313845&site=ehost-live&scope=site VL - 30 ID - 303 ER - TY - JOUR AB - Summary Background This paper forms part of the first British Armed forces qualitative nursing research study undertaken on deployment. Aim To provide an analysis of the impact and effectiveness of the pre-deployment educational preparation and clinical placements provided for military nurses. Theory & methods A Constructivist Grounded Theory was utilised with data collected through semi-structured interviews with 18 nurses based in Camp Bastion Hospital, Afghanistan during 2013. Results Initial coding indicated 21 educational preparation and clinical placement categories that influenced the delivery of nursing care. Analysis of these elements led to the identification of four major clusters: Military Nursing Care; Military Nurse Education; Unique Hospital Environment and Clinical Placements. Discussion Educational preparation consists of completing deployable operational nursing competencies, specialist training and individual tailored courses. This strategy was viewed as proving the appropriate academic requirement. However, training would be enhanced by introducing a formalised military preceptorship programme focussing on fundamental nursing skills. Caring for children was a particular concern, and it was emphasised that educational courses must be combined with a standardised clinical placement policy. Adequate clinical exposure can be challenging as nurses are not routinely exposed to War Zone levels of trauma in the UK. Clinical placements need to be standardised and harmonised, and located in areas where nurses cared for patients with similar injury patterns to those witnessed on deployment. Current NHS Trust placements can reduce the opportunities for employment in suitable clinical environments and diminishing the openings for collective military training. Better use should be made of clinical rotation programmes, including high dependency units, elective surgery, medical assessment units, paediatrics, and outreach teams such as burns and plastic surgery and pain management. Practice Educators should be utilised to provide education, mentorship, supervision and continuing personal development in the operational arena. The paper considers post-Afghanistan future options. AD - Academic Department of Military Nursing, Royal Centre for Defence Medicine, ICT Centre, Birmingham Research Park, Vincent Drive, Birmingham B15 2SQ, United Kingdom Eastham Group Practice, Treetops Primary Healthcare Centre, 47 Bridle Road, Bromborough Wirral CH62 6EE, United Kingdom Army Medical Directorate, Former Staff College, Slim Road, Camberley GU15 4NP, United Kingdom Defence Healthcare Education & Training, Defence Medical Services (Whittington), Lichfield, Staffordshire WS14 9PY, United Kingdom Faculty of Health & Life Sciences, University of Northumbria, E210, 2nd Floor Coach Lane Campus, West Benton Newcastle upon Tyne NE7 7XA, United Kingdom Faculty of Health and Social Care, University of Chester, Senate House CSH109, Parkgate Road, Chester CH1 4BJ, United Kingdom AN - 103859986. Language: English. Entry Date: 20150106. Revision Date: 20200708. Publication Type: Journal Article AU - Finnegan, Alan AU - Finnegan, Sara AU - Bates, David AU - Ritsperis, Debra AU - McCourt, Kath AU - Thomas, Mike DB - cin20 DO - 10.1016/j.nedt.2014.07.008 DP - EBSCOhost IS - 1 KW - Military Nursing -- Education Education, Nursing Education, Clinical Human Afghanistan Military Deployment United Kingdom Grounded Theory Semi-Structured Interview Coding Student Placement Preceptorship Qualitative Studies Mentorship N1 - research. Journal Subset: Core Nursing; Europe; Nursing; Peer Reviewed; UK & Ireland. Special Interest: Military/Uniformed Services; Nursing Education. NLM UID: 8511379. PMID: NLM25151019. PY - 2015 SN - 0260-6917 SP - 104-112 ST - Preparing British Military nurses to deliver nursing care on deployment. An Afghanistan study T2 - Nurse Education Today TI - Preparing British Military nurses to deliver nursing care on deployment. An Afghanistan study UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=103859986&site=ehost-live&scope=site VL - 35 ID - 466 ER - TY - JOUR AB - Adolescents who experience pain often face competing goals and have to choose whether to approach (confront) or avoid pain. This study investigates the decisions adolescents make when their pain conflicts with a valued goal. Adolescents between the ages of 15 and 18 years (N = 170) completed questionnaires on general and pain-specific anxiety, courage, and dispositional avoidance. Adolescents were presented with 16 vignettes (8 high pain intensity, 8 low pain intensity), which described pain conflicting with a goal (eg, doing well at school, seeing friends). Adolescents rated goals for importance and reported how likely they would be to approach or avoid each pain. Adolescents were more likely to avoid and were more fearful of high pain intensity than low pain intensity vignettes. Pain anxiety predicted higher levels of avoidance for both pain intensities. General anxiety was not a significant predictor of avoidance for either pain intensity. Goal importance promoted approach of goals, but only when pain was described as intense. However, pain anxiety predicted avoidance beyond the importance of goals for high pain intensity vignettes. In addition, we compared approach-avoidance of adolescents with and without chronic pain; analyses revealed no differences in approach-avoidance behaviour. We also found that behavioural endurance was predictive of approach and dispositional avoidance predicted higher avoidance, but courage was not predictive of behaviour in this task. We adopt a motivational perspective when interpreting the findings and consider whether the fear-avoidance model should be extended to include the function of avoidance or approach in the pursuit of a desired goal. AD - Centre for Pain Research, University of Bath, Bath, United Kingdom Department of Psychology, University of Bath, Bath, United Kingdom AN - 112569671. Language: English. Entry Date: 20160826. Revision Date: 20210115. Publication Type: journal article AU - Fisher, Emma AU - Keogh, Edmund AU - Eccleston, Christopher DB - cin20 DO - 10.1097/j.pain.0000000000000383 DP - EBSCOhost IS - 2 KW - Pain -- Physiopathology Pain -- Psychosocial Factors Learning Male Anxiety -- Diagnosis Female Goals and Objectives Adolescence Pain Measurement Psychological Tests Anxiety -- Etiology Analysis of Variance Fear Human N1 - research; tables/charts. Journal Subset: Biomedical; Continental Europe; Europe; Peer Reviewed. NLM UID: 7508686. PMID: NLM26458091. PY - 2016 SN - 0304-3959 SP - 370-376 ST - Adolescents' approach-avoidance behaviour in the context of pain T2 - PAIN TI - Adolescents' approach-avoidance behaviour in the context of pain UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=112569671&site=ehost-live&scope=site VL - 157 ID - 427 ER - TY - JOUR AB - Background: Chronic pain is common during childhood and adolescence and is associated with negative outcomes such as increased severity of pain, reduced function (e.g. missing school), and low mood (e.g. high levels of depression and anxiety). Psychological therapies, traditionally delivered face-to-face with a therapist, are efficacious at reducing pain intensity and disability. However, new and innovative technology is being used to deliver these psychological therapies remotely, meaning barriers to access to treatment such as distance and cost can be removed or reduced. Therapies delivered with technological devices, such as the Internet, computer-based programmes, smartphone applications, or via the telephone, can be used to deliver treatment to children and adolescents with chronic pain.Objectives: To determine the efficacy of psychological therapies delivered remotely compared to waiting-list, treatment-as-usual, or active control treatments, for the management of chronic pain in children and adolescents.Search Methods: We searched four databases (CENTRAL, MEDLINE, EMBASE, and PsycINFO) from inception to June 2014 for randomised controlled trials of remotely delivered psychological interventions for children and adolescents (0 to 18 years of age) with chronic pain. We searched for chronic pain conditions including, but not exclusive to, headache, recurrent abdominal pain, musculoskeletal pain, and neuropathic pain. We also searched online trial registries for potential trials. A citation and reference search for all included studies was conducted.Selection Criteria: All included studies were randomised controlled trials that investigated the efficacy of a psychological therapy delivered remotely via the Internet, smartphone device, computer-based programme, audiotapes, or over the phone in comparison to an active, treatment-as-usual, or waiting-list control. We considered blended treatments, which used a combination of technology and face-to-face interaction. We excluded interventions solely delivered face-to-face between therapist and patient from this review. Children and adolescents (0 to 18 years of age) with a primary chronic pain condition were the target of the interventions. Each comparator arm, at each extraction point had to include 10 or more participants.Data Collection and Analysis: For the analyses, we combined all psychological therapies. We split pain conditions into headache and mixed (non-headache) pain and analysed them separately. Pain, disability, depression, anxiety, and adverse events were extracted as primary outcomes. We also extracted satisfaction with treatment as a secondary outcome. We considered outcomes at two time points: first immediately following the end of treatment (known as 'post-treatment'), and second, any follow-up time point post-treatment between 3 and 12 months (known as 'follow-up'). We assessed all included studies for risk of bias.Main Results: Eight studies (N = 371) that delivered treatment remotely were identified from our search; five studies investigated children with headache conditions, one study was with children with juvenile idiopathic arthritis, and two studies included mixed samples of children with headache and mixed (i.e. recurrent abdominal pain, musculoskeletal pain) chronic pain conditions. The average age of children receiving treatment was 12.57 years.For headache pain conditions, we found one beneficial effect of remotely delivered psychological therapy. Headache severity was reduced post-treatment (risk ratio (RR) = 2.65, 95% confidence interval (CI) 1.56 to 4.50, z = 3.62,p < 0.01, number needed to treat to benefit (NNTB) = 2.88). For mixed pain conditions, we found only one beneficial effect: psychological therapies reduced pain intensity post-treatment (standardised mean difference (SMD) = -0.61, 95% CI -0.96 to -0.25, z = 3.38, p < 0.01). No effects were found for reducing pain at follow-up in either analysis. For headache and mixed conditions, there were no beneficial effects of psychological therapies delivered remotely for disability p st-treatment and a lack of data at follow-up meant no analyses could be run. Only one analysis could be conducted for depression outcomes. We found no beneficial effect of psychological therapies in reducing depression post-treatment for headache conditions. Only one study presented data in children with mixed pain conditions for depressive outcomes and no data were available for either condition at follow-up. Only one study presented anxiety data post-treatment and no studies reported follow-up data, therefore no analyses could be run. Further, there were no data available for adverse events, meaning that we are unsure whether psychological therapies are harmful to children who receive them. Satisfaction with treatment is described qualitatively.'Risk of bias' assessments were low or unclear. We judged selection, detection, and reporting biases to be mostly low risk for included studies. However, judgements made on performance and attrition biases were mostly unclear.Authors' Conclusions: Psychological therapies delivered remotely, primarily via the Internet, confer benefit in reducing the intensity or severity of pain after treatment across conditions. There is considerable uncertainty around these estimates of effect and only eight studies with 371 children contribute to the conclusions. Future studies are likely to change the conclusions reported here. All included trials used either behavioural or cognitive behavioural therapies for children with chronic pain, therefore we cannot generalise our findings to other therapies. However, satisfaction with these treatments was generally positive. Larger trials are needed to increase our confidence in all conclusions regarding the efficacy of remotely delivered psychological therapies. Implications for practice and research are discussed. AD - Centre for Pain Research, University of Bath, Claverton Down, Bath, UK, BA2 7AY AN - 109805439. Language: English. Entry Date: 20101029. Revision Date: 20151028. Publication Type: journal article AU - Fisher, E. AU - Law, E. AU - Palermo, T. M. AU - Eccleston, C. AU - Fisher, Emma AU - Law, Emily AU - Palermo, Tonya M. AU - Eccleston, Christopher DB - cin20 DO - 10.1002/14651858.CD011118.pub2 DP - EBSCOhost IS - 3 KW - Chronic Pain -- Therapy Psychotherapy -- Methods Therapy, Computer Assisted Adolescence Arthritis, Juvenile Rheumatoid Child Cochrane Library Confidence Intervals Depression -- Therapy Embase Headache Human Internet Medline Pain Measurement Psycinfo Smartphone Systematic Review Telephone Treatment Outcomes N1 - research; systematic review. Journal Subset: Europe; Peer Reviewed; UK & Ireland. Special Interest: Evidence-Based Practice; Pain and Pain Management; Pediatric Care; Psychiatry/Psychology. Grant Information: K24 HD060068/HD/NICHD NIH HHS/United States. NLM UID: 100909747. Cochrane AN: CD011118. PMID: NLM25803793. PY - 2015 SN - 1469-493X SP - N.PAG-N.PAG ST - Psychological therapies (remotely delivered) for the management of chronic and recurrent pain in children and adolescents T2 - Cochrane Database of Systematic Reviews TI - Psychological therapies (remotely delivered) for the management of chronic and recurrent pain in children and adolescents UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=109805439&site=ehost-live&scope=site ID - 456 ER - TY - JOUR AB - Purpose: To describe the physical therapy management of a pediatric patient with bilateral lower extremity complex regional pain syndrome (CRPS). Case Description: The participant was a 13-year-old adolescent girl who was admitted to an inpatient rehabilitation unit with bilateral lower extremity CRPS-I. Examination included assessment of lower extremity active range of motion, transfers, mobility, and completion of the Functional Independence Measure for Children (WeeFIM). Intervention consisted of gradual desensitization techniques, progressive weight bearing and mobility, functional transfer training, progressive strengthening, and cardiovascular exercises—all conducted using a modified pain exposure therapy approach. Outcome: WeeFIM scores increased to modified independence or independent in all areas. Discussion: The severity of the patient's CRPS necessitated a progressive and function-based approach to physical therapy management. Motivation, a pain exposure-based approach, and a multidisciplinary team approach appeared to affect the participant's recovery of function and reintegration into school and leisure activities. AD - Department of Physical Therapy, Mary Free Bed Rehabilitation Hospital, Grand Rapids, Michigan Department of Physical Therapy, Grand Valley State University, Grand Rapids, Michigan AN - 110369365. Language: English. Entry Date: 20180409. Revision Date: 20190708. Publication Type: Article AU - Fisher-Pipher, Sarah AU - Kenyon, Lisa K. DA - Winter2015 DB - cin20 DO - 10.1097/PEP.0000000000000175 DP - EBSCOhost IS - 4 KW - Complex Regional Pain Syndromes -- Therapy -- In Adolescence Physical Therapy -- Methods Female Adolescence Physical Examination Pain Management Desensitization, Psychologic Resistance Training Physical Mobility Functional Training N1 - case study; tables/charts. Journal Subset: Allied Health; Peer Reviewed; USA. Special Interest: Pediatric Care; Physical Therapy. NLM UID: 8912748. PMID: NLM26397095. PY - 2015 SN - 0898-5669 SP - 443-451 ST - Management of Bilateral Complex Regional Pain Syndrome in a Pediatric Patient T2 - Pediatric Physical Therapy TI - Management of Bilateral Complex Regional Pain Syndrome in a Pediatric Patient UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=110369365&site=ehost-live&scope=site VL - 27 ID - 435 ER - TY - JOUR AB - Background: To date, no German instrument exists to measure pain-related fear in paediatric pain populations. The objective of the current study was to determine the construct validity of the translated German fear of pain questionnaire for children (GFOPQ-C) in a sample of children with mixed chronic pain disorders by testing the underlying factor structure, and its psychometric properties.Method: N = 241 children with mixed chronic pain disorders (aged 8-19 years) presenting to a specialized pain clinic completed the GFOPQ-C and several other pain, fear and disability measures.Results: The two-factor structure of the FOPQ-C (fear, avoidance) was replicated. Internal consistency for the shortened German version was good for both subscales (Fear subscale: α = 0.89; avoidance subscale: α = 0.76). As expected, the fear subscale correlated highly with anxiety sensitivity (r = 0.63), pain catastrophizing (r = 0.62) and general anxiety (r = 0.54), while the avoidance subscale was more closely related to disability (r = 0.24) and school functioning (r = 0.28). Pain-related fear differed in children with chronic pain depending on their pain location with higher fear ratings in children with abdominal pain and musculoskeletal pain.Conclusion: The GFOPQ-C is a valid instrument that assesses two distinct dimensions of pain-related fear in children: fear and avoidance. Future research is needed to evaluate the impact of increased pain-related fear on outcomes over time as well as to examine pain-related fear among healthy children. This will enhance our knowledge of who might be particularly vulnerable to potentially dysfunctional trajectories, such as ongoing pain or anxiety symptoms.Significance: The current study validates the first tool to assess pain-related fear in German-speaking children with chronic pain. Findings support two distinct domains: fear and activity avoidance. AD - German Paediatric Pain Centre, Children's and Adolescent's Hospital, Datteln Germany Department of Children's Pain Therapy and Paediatric Palliative Care, Faculty of Health – School of Medicine, Witten/Herdecke University, Germany Department of Psychology, Institute of Clinical Psychology and Psychotherapy, University of Cologne, Germany Department of Anaesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, USA Department of Clinical Child and Adolescent Psychology and Psychotherapy, University of Trier, Germany AN - 124091679. Language: English. Entry Date: 20180220. Revision Date: 20190619. Publication Type: journal article AU - Flack, F. AU - Gerlach, A. L. AU - Simons, L. E. AU - Zernikow, B. AU - Hechler, T. DB - cin20 DO - 10.1002/ejp.1022 DP - EBSCOhost IS - 7 KW - Chronic Disease -- Psychosocial Factors Anxiety -- Psychosocial Factors Chronic Pain -- Physiopathology Somatoform Disorders -- Physiopathology Phobic Disorders -- Psychosocial Factors Fear Pain Clinics Disabled Child Psychometrics Pain Measurement -- Methods Chronic Pain -- Psychosocial Factors Reproducibility of Results Adolescence Human Questionnaires N1 - research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Continental Europe; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. Instrumentation: German Fear Of Pain Questionnaire For Children (GFOPQ-C). NLM UID: 9801774. PMID: NLM28370851. PY - 2017 SN - 1090-3801 SP - 1224-1233 ST - Validation of the German fear of pain questionnaire in a sample of children with mixed chronic pain conditions T2 - European Journal of Pain TI - Validation of the German fear of pain questionnaire in a sample of children with mixed chronic pain conditions UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=124091679&site=ehost-live&scope=site VL - 21 ID - 355 ER - TY - JOUR AB - Fear of pain plays an important role in the maintenance of chronic pain. It may be reduced through exposure therapy. This 2-arm parallel samples randomized controlled trial aimed to investigate whether interoceptive exposure (IE) therapy enhances reductions in fear of pain (primary outcome), pain (pain intensity, pain-related disability, and school absence), and emotional characteristics (anxiety and catastrophizing) when implemented as an adjunctive treatment in the context of intensive interdisciplinary pain treatment for pediatric chronic pain patients. N = 126 adolescents, aged 11 to 17 years, who were receiving standard intensive interdisciplinary pain treatment were randomly assigned to either receive additional IE (n = 64) or additional relaxation therapy (RT) (n = 62). All patients were assessed at admission, discharge, and 3 months after discharge. The data of N = 104 patients were analyzed. Significant large reductions were found in the total score and subscale scores of the Fear of Pain Questionnaire for Children in both study groups (eg, total score [range 0-60; IE/RT]: admission M = 23.5/24.9; discharge M = 16.0/19.7; P < 0.001, (Equation is included in full-text article.)= 0.27) and mainly large reductions in pain characteristics. There were no greater decreases in the IE group (P > 0.1). The exploratory analyses revealed that the patients with high fear of pain before treatment (P < 0.05, (Equation is included in full-text article.)> 0.03) and the patients with abdominal pain (P < 0.04, (Equation is included in full-text article.)> 0.25) showed greater decreases in their fear of pain (total and subscale score) in the IE group than in the RT group. In conclusion, the results suggest that IE is not particularly effective for all the pediatric chronic pain patients, but the patients with high fear of pain before treatment and with abdominal pain strongly benefit from this intervention. AD - German Paediatric Pain Centre, Children's and Adolescents' Hospital, Datteln, Germany Department of Children's Pain Therapy and Paediatric Palliative Care, Faculty of Health, School of Medicine, Witten/Herdecke University, Witten, Germany Faculty of Business Management and Social Sciences, University of Applied Sciences Osnabrück, Osnabrück, Germany Faculty of Health, Department of Psychology and Psychotherapy, Witten/Herdecke University, Witten, Germany AN - 133583529. Language: English. Entry Date: 20190402. Revision Date: 20210115. Publication Type: journal article AU - Flack, Florentina AU - Stahlschmidt, Lorin AU - Dobe, Michael AU - Hirschfeld, Gerrit AU - Strasser, Alexa AU - Michalak, Johannes AU - Wager, Julia AU - Zernikow, Boris DB - cin20 DO - 10.1097/j.pain.0000000000001321 DP - EBSCOhost IS - 11 KW - Behavior Therapy -- Methods Chronic Pain -- Psychosocial Factors Chronic Pain -- Therapy Stress, Psychological -- Etiology Treatment Outcomes Perception Child Adolescence Analysis of Variance Prospective Studies Male Pain Measurement Human Female Validation Studies Comparative Studies Evaluation Research Multicenter Studies Randomized Controlled Trials N1 - research; randomized controlled trial. Journal Subset: Biomedical; Continental Europe; Europe; Peer Reviewed. Special Interest: Evidence-Based Practice. NLM UID: 7508686. PMID: NLM29939961. PY - 2018 SN - 0304-3959 SP - 2223-2233 ST - Efficacy of adding interoceptive exposure to intensive interdisciplinary treatment for adolescents with chronic pain: a randomized controlled trial T2 - PAIN TI - Efficacy of adding interoceptive exposure to intensive interdisciplinary treatment for adolescents with chronic pain: a randomized controlled trial UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=133583529&site=ehost-live&scope=site VL - 159 ID - 280 ER - TY - JOUR AB - Background. Traditional negative pressure wound therapy (NPWT) devices, such as the electrically powered V.A.C.® Therapy System (KCI, San Antonio, TX), are important tools in the treatment of both acute and chronic wounds.The following describes the first clinical experience using a novel, non-electrically powered, ultraportable NPWT device called the Smart Negative Pressure (SNaPTM) Wound Care System (Spiracur, Sunnyvale, CA). Methods. Twelve consecutive adult subjects with chronic wounds ranging from neuropathic wounds to venous stasis ulcers were treated with the SNaP System at an academic outpatient dermatology clinic. Subjects were followed biweekly for complications and wound healing progression over a 4-week period. Results. Of the 12 subjects treated, 5 achieved complete wound healing within 4 weeks. All subjects demonstrated healing after treatment with the SNaP System, and statistically significant healing was reached at 4 weeks (P < 0.01) for patients who were able to complete the treatment protocol. Use of the SNaP System promoted cleaner wound beds with robust granulation tissue formation. There were no serious adverse events directly related to the device. The most common complaint was mild or moderate wound pain in 3 of 12 subjects. Conclusion. These findings support the safety and potential clinical utility of a new ultraportable NPWT device for the treatment of chronic wounds. AD - Department of Surgery, Stanford University School of Medicine, Stanford, CA AN - 105106492. Language: English. Entry Date: 20101112. Revision Date: 20150820. Publication Type: Journal Article AU - Fong, K. D. AU - Hu, D. AU - Eichstadt, S. L. AU - Gorell, E. AU - Munoz, C. A. AU - Lorenz, H. P. AU - Chang, A. L. S. DB - cin20 DP - EBSCOhost IS - 9 KW - Negative Pressure Wound Therapy -- Equipment and Supplies Product Evaluation Wounds, Chronic -- Therapy Adolescence Aged Aged, 80 and Over Convenience Sample Female Foam Dressings Human Male Middle Age Patient Satisfaction Prospective Studies Questionnaires Treatment Outcomes N1 - pictorial; research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 9010276. PY - 2010 SN - 1044-7946 SP - 230-236 ST - Initial clinical experience using a novel ultraportable negative pressure wound therapy device T2 - Wounds: A Compendium of Clinical Research & Practice TI - Initial clinical experience using a novel ultraportable negative pressure wound therapy device UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105106492&site=ehost-live&scope=site VL - 22 ID - 620 ER - TY - JOUR AB - Aim: To estimate direct and indirect costs in patients with a diagnosis of cluster headache in the US.Methods: Adult patients (18-64 years of age) enrolled in the Marketscan Commercial and Medicare Databases with ≥2 non-diagnostic outpatient (≥30 days apart between the two outpatient claims) or ≥1 inpatient diagnoses of cluster headache (ICD-9-CM code 339.00, 339.01, or 339.02) between January 1, 2009 and June 30, 2014, were included in the analyses. Patients had ≥6 months of continuous enrollment with medical and pharmacy coverage before and after the index date (first cluster headache diagnosis). Three outcomes were evaluated: (1) healthcare resource utilization, (2) direct healthcare costs, and (3) indirect costs associated with work days lost due to absenteeism and short-term disability. Direct costs included costs of all-cause and cluster headache-related outpatient, inpatient hospitalization, surgery, and pharmacy claims. Indirect costs were based on an average daily wage, which was estimated from the 2014 US Bureau of Labor Statistics and inflated to 2015 dollars.Results: There were 9,328 patients with cluster headache claims included in the analysis. Cluster headache-related total direct costs (mean [standard deviation]) were $3,132 [$13,396] per patient per year (PPPY), accounting for 17.8% of the all-cause total direct cost. Cluster headache-related inpatient hospitalizations ($1,604) and pharmacy ($809) together ($2,413) contributed over 75% of the cluster headache-related direct healthcare cost. There were three sub-groups of patients with claims associated with indirect costs that included absenteeism, short-term disability, and absenteeism + short-term disability. Indirect costs PPPY were $4,928 [$4,860] for absenteeism, $803 [$2,621] for short-term disability, and $3,374 [$3,198] for absenteeism + disability.Conclusion: Patients with cluster headache have high healthcare costs that are associated with inpatient admissions and pharmacy fulfillments, and high indirect costs associated with absenteeism and short-term disability. AD - a Eli Lilly and Company , Indianapolis , IN , USA b Truven Health Analytics, an IBM Company , Ann Arbor , MI , USA AN - 126216401. Language: English. Entry Date: In Process. Revision Date: 20180825. Publication Type: journal article. Journal Subset: Biomedical AU - Ford, Janet H. AU - Nero, Damion AU - Kim, Gilwan AU - Chu, Bong Chul AU - Fowler, Robert AU - Ahl, Jonna AU - Martinez, James M. DB - cin20 DO - 10.1080/13696998.2017.1404470 DP - EBSCOhost KW - Health Care Costs -- Statistics and Numerical Data Economic Aspects of Illness Cluster Headache -- Economics Cluster Headache -- Drug Therapy Cluster Headache -- Epidemiology Hospitalization -- Economics Male Female Managed Care Programs -- Utilization Adolescence Middle Age Adult Insurance Cluster Headache -- Diagnosis Young Adult Resource Databases Hospitalization -- Statistics and Numerical Data Severity of Illness Indices United States Incidence Managed Care Programs -- Economics Absenteeism Scales Short Portable Mental Status Questionnaire N1 - Health Services Administration; USA. Instrumentation: Short Portable Mental Status Questionnaire (SPMSQ) (Pfeiffer); Work Environment Scale (WES) (Moos et al). NLM UID: 9892255. PMID: NLM29125368. PY - 2017 SN - 1369-6998 SP - 1-11 ST - Societal burden of cluster headache in the United States: a descriptive economic analysis T2 - Journal of Medical Economics TI - Societal burden of cluster headache in the United States: a descriptive economic analysis UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=126216401&site=ehost-live&scope=site ID - 334 ER - TY - JOUR AB - Adolescents with chronic pain are at risk for impairment in their friendships. They miss out on leisure activities, have increased school absence, may have fewer friends, are at an increased risk for victimization, and may be perceived by peers as less likeable. To help determine the source of these problems, the Social Information Processing Model (SIP) was adapted using narrative vignettes to determine if adolescents with chronic pain interpret friendship interactions differently in terms of supportive and nonsupportive behaviors compared to healthy peers. One hundred seven adolescents, 45 with chronic pain, completed the vignette questionnaire and a battery of measures. The vignette questionnaire included 12 vignettes to capture 3 steps in SIP processing: interpretation of cues, response construction, and response decision. Participants with chronic pain rated nonsupportive vignettes more negatively than healthy controls and indicated they would enact supportive behaviors towards the chronic pain character more often if they had been the healthy character. Age, sex, and internalizing measures did not significantly contribute to the findings. Chronic pain explained 6.5% of variance in the ratings of nonsupportive vignettes and 10.1% of the variance in supportive behavior selection. Adolescents with chronic pain may interpret nonsupportive social situations with close friends as more distressing. The endorsement of more supportive behaviors may indicate a need for, and expectation of, supportive behaviors from friends. When adolescents with chronic pain do not perceive friends as providing support, they may avoid these social situations. AD - Dalhousie University, Halifax, NS, Canada IWK Health Centre, Halifax, NS, Canada University of Toronto/Hospital for Sick Children, Toronto, ON, Canada University of Alberta/Stollery Children's Hospital, Edmonton, AB, Canada University of Calgary/Alberta Children's Hospital, Calgary, AB, Canada Dalhousie University, Halifax, NS, Canada; IWK Health Centre, Halifax, NS, Canada. AN - 104597911. Language: English. Entry Date: 20120831. Revision Date: 20210115. Publication Type: journal article AU - Forgeron, P. A. AU - McGrath, P. AU - Stevens, B. AU - Evans, J. AU - Dick, B. AU - Finley, G. A. AU - Carlson, T. AU - Forgeron, Paula A. AU - McGrath, Patrick AU - Stevens, Bonnie AU - Evans, Joan AU - Dick, Bruce AU - Finley, Allen G. AU - Carlson, Torie DB - cin20 DO - 10.1016/j.pain.2011.09.001 DP - EBSCOhost IS - 12 KW - Adolescent Behavior Anxiety Disorders -- Psychosocial Factors Chronic Pain -- Psychosocial Factors Depression -- Psychosocial Factors Social Behavior Support, Psychosocial Adolescence Anxiety Disorders -- Epidemiology Chronic Pain -- Epidemiology Comorbidity -- Trends Depression -- Epidemiology Female Friendship Loneliness -- Psychosocial Factors Male N1 - research. Journal Subset: Biomedical; Continental Europe; Europe; Peer Reviewed. Grant Information: //Canadian Institutes of Health Research/Canada. NLM UID: 7508686. PMID: NLM21963240. PY - 2011 SN - 0304-3959 SP - 2773-2780 ST - Social information processing in adolescents with chronic pain: my friends don't really understand me T2 - PAIN TI - Social information processing in adolescents with chronic pain: my friends don't really understand me UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104597911&site=ehost-live&scope=site VL - 152 ID - 570 ER - TY - JOUR AB - Background: There had been reports of adolescents using hand sanitizers to obtain alcohol and ending up in emergency departments with alcohol poisoning.Objective: This study aimed to describe the pattern of adolescent ingestions of hand sanitizers reported to a statewide poison center system.Subjects: Our study subjects included patients aged 13-19 years who reported hand sanitizer ingestions as reported to Texas poison centers during 2000-2013.Materials and Methods: The distribution of the ingestions was determined for various demographic and clinical factors.Results: Of 385 total cases, 61% of the patients were male, and the mean age was 15.3 years. The ingestion reason was unintentional (61%), intentional abuse/misuse (18%), and malicious (10%). Ingestion site was most frequently reported to be the patient's own residence (53%), followed by school (35%). About 77% of the patients were managed on site. The medical outcome was serious (moderate effect or unable to follow-potentially toxic) in 5% of the cases. The most frequently reported adverse clinical effects were vomiting (5%), abdominal pain (4%), nausea (4%), throat irritation (4%), and drowsiness (2%).Conclusion: Adolescents who ingested hand sanitizers were more likely to be male and younger. One-third of the ingestions occurred at school, suggesting that school personnel might be made aware of the potential problem of hand sanitizer ingestions by adolescents. Nevertheless, despite the potential for serious outcomes from adolescent hand sanitizer ingestion, most of the ingestions reported to poison centers are not likely to be serious and can be successfully managed outside of a healthcare facility. AN - 109704780. Language: English. Entry Date: 20150923. Revision Date: 20160904. Publication Type: journal article. Journal Subset: Biomedical AU - Forrester, Mathias B. DB - cin20 DO - 10.1515/ijamh-2014-0014 DP - EBSCOhost IS - 1 N1 - Middle East; Peer Reviewed. Special Interest: Pediatric Care. NLM UID: 8506960. PMID: NLM24887952. PY - 2015 SN - 0334-0139 SP - 69-72 ST - Characteristics of hand sanitizer ingestions by adolescents reported to poison centers T2 - International Journal of Adolescent Medicine & Health TI - Characteristics of hand sanitizer ingestions by adolescents reported to poison centers UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=109704780&site=ehost-live&scope=site VL - 27 ID - 457 ER - TY - JOUR AB - functional pain syndromes (SDF) has been founded. This study has the following objectives: 1) describe the epidemiology of cases with SDF followed between 2007-2014; 2) describe methods and instruments used in physiotherapy treatment of SDF; 3) detect strengths and operational aspects to improve of the physiotherapy treatment. Method: analytic retrospective study. Results: 89 cases with a mean age of 12.7 years and predominantly female (70.8%). were followed during the period 2007-2014. In 30.3% school attendance was irregular, sport was interrupted or not practiced in 46%, social participation absent or limited in 24.7%. The first pain assessment had a mean value of 6.6 (NRS) and it was often localized in the lower limbs (75.3%). 76.4% had needed a physiotherapy treatment with physical therapy, heat therapy, postural care, orthoses and aids, advices of motor activity. For the resolution of symptoms and the average discharge time was 9.2 months. Conclusion: The epidemiological characteristics of the sample are similar to those reported in the literature. It is confirmed the important functional and social fallout of the SDF and the need for multidisciplinary management where the physical therapist has a central role in functional recovery and pain reduction. It will be necessary in the future use of validated rating scales that measure objectively the functional framework and check the quality perceived by parents on the physiotherapy management mode implemented at the AOUM. Background: Presso l'Azienda Ospedaliero-Universitaria Meyer (AOUM) di Firenze dal 2007 è operativo un ambulatorio multidisciplinare dedicato alla diagnosi e al trattamento delle sindromi da dolore funzionale (SDF). Questo studio ha come obiettivi: 1) descrivere l'epidemiologia dei casi con SDF seguiti dal 2007 al 2014; 2) descrivere modalità e strumenti fisioterapici utilizzati nel trattamento delle SDF; 3) rilevare punti di forza ed aspetti operativi fisioterapici da migliorare. Metodo: Studio analitico retrospettivo Risultati: Nel periodo 2007-2014 sono stati seguiti 89 casi con età media di 12,7 anni e di sesso prevalentemente femminile (70,8%). Nel 30,3% la frequenza scolastica era irregolare, l'attività sportiva interrotta o non praticata nel 46%, la partecipazione sociale assente o limitata nel 24,7%. Alla prima valutazione il dolore aveva un valore medio di 6,6 (scala NRS), spesso localizzato agli arti inferiori (75,3%). Il 76,4% aveva necessitato di un trattamento fisioterapico con chinesiterapia, termoterapia, cura posturale, ortesi e ausili, indicazioni di attività motoria. Per la risoluzione dei sintomi e la dimissione il tempo medio era 9,2 mesi. Conclusioni: Le caratteristiche epidemiologiche del campione esaminato sono sovrapponibili a quelle riportate in letteratura; si confermano l'importante ricaduta funzionale e sociale delle SDF e la necessità di una presa in carico multidisciplinare dove il fisioterapista ha un ruolo centrale per il recupero funzionale e la riduzione del dolore. Sarà necessario in futuro utilizzare scale di valutazione validate che misurino oggettivamente il quadro funzionale e verificare la qualità percepita dai genitori sulle modalità di gestione fisioterapica attuata presso l'AOUM. AD - Fisioterapiste - AOU Meyer, Firenze Fisioterapista - Fondazione Don Carlo Gnocchi, Firenze Fisioterapista - libero professionista, Firenze Medico anestesista - AOU Meyer, Firenze AN - 120052897. Language: Italian. Entry Date: 20180427. Revision Date: 20180427. Publication Type: Article AU - Fortini, V. AU - Allighieri, M. AU - Ciullini, P. AU - Taddei, C. AU - Rizzo, G. DB - cin20 DP - EBSCOhost IS - 4 KW - Pediatric Care Chronic Pain -- Epidemiology -- Italy Chronic Pain -- Rehabilitation Physical Therapy -- Methods Physical Therapy -- Equipment and Supplies Human Male Female Child Adolescence Italy Retrospective Design Case Studies N1 - research; tables/charts. Journal Subset: Allied Health; Continental Europe; Editorial Board Reviewed; Europe; Peer Reviewed. Special Interest: Pediatric Care. PY - 2016 SN - 1828-3942 SP - 28-37 ST - LA FISIOTERAPIA NELLE SINDROMI DA DOLORE FUNZIONALE IN ETA' PEDIATRICA: STUDIO RETROSPETTIVO T2 - Scienza Riabilitativa TI - LA FISIOTERAPIA NELLE SINDROMI DA DOLORE FUNZIONALE IN ETA' PEDIATRICA: STUDIO RETROSPETTIVO UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=120052897&site=ehost-live&scope=site VL - 18 ID - 389 ER - TY - JOUR AB - Quality improvement measurement instruments for pediatric postoperative pain management are virtually nonexistent. Without standardized instruments to measure pediatric pain management outcomes, practitioners are hampered in their efforts to improve the quality of pain management for children. In this study, instruments for children (8--12 years) and parents were developed and tested to measure the quality of children's postoperative pain management. The child (Child TQPM) and parent (Parent TQPM) Total Quality Pain Management instruments were tested with 50 parent/child dyads across two large treatment centers. The pain rating scale modified for these instruments demonstrated good criterion validity with the well established Varni/Thompson Pediatric Pain Questionnaire Visual Analogue Scale. Parent--child agreement was described for responses across instruments. Construct validity was examined through selected inter-item relationships. Psychometric analyses support the initial measurement properties of the pediatric TQPM instruments. AD - School of Nursing, University of Colorado Health Sciences Center, Denver, CO 80262, USA School of Nursing, C288-10, University of Colorado, Health Sciences Center, 4200 East Ninth Avenue, Denver, CO 80262 AN - 106942908. Language: English. Entry Date: 20020726. Revision Date: 20200701. Publication Type: journal article AU - Foster, R. L. AU - Varni, J. W. AU - Foster, Roxie L. AU - Varni, James W. DB - cin20 DO - 10.1016/s0885-3924(01)00411-0 DP - EBSCOhost IS - 3 KW - Postoperative Pain -- Therapy -- In Infancy and Childhood Pain Measurement Quality Assessment Clinical Assessment Tools Instrument Validation Funding Source Parents Quality Improvement Validation Studies Correlational Studies Convenience Sample Surveys Questionnaires Record Review Scales Patient Attitudes Parental Attitudes Analgesics -- Therapeutic Use Patient Satisfaction Absenteeism Construct Validity Criterion-Related Validity Spearman's Rank Correlation Coefficient Correlation Coefficient Kappa Statistic Descriptive Statistics Age Factors Sex Factors Male Female Child Inpatients Hospitals, Pediatric Colorado California Human N1 - pictorial; research; tables/charts. Journal Subset: Biomedical; Core Nursing; Nursing; Peer Reviewed; USA. Instrumentation: Varni/Thompson Pedatric Pain Questionnaire Visual Analogue Scale (VAS). Grant Information: Funded by a grant from Abbott Laboratories, Hospital Products Division. NLM UID: 8605836. PMID: NLM11888718. PY - 2002 SN - 0885-3924 SP - 201-210 ST - Measuring the quality of children's postoperative pain management: initial validation of the child/parent Total Quality Pain Management (TQPM) instruments T2 - Journal of Pain & Symptom Management TI - Measuring the quality of children's postoperative pain management: initial validation of the child/parent Total Quality Pain Management (TQPM) instruments UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106942908&site=ehost-live&scope=site VL - 23 ID - 800 ER - TY - JOUR AB - Meralgia paresthetica is a chronic pain syndrome that is extremely rare in the pediatric population. It is manifested by hypesthesia or pain in the distribution of the lateral femoral cutaneous nerve (LFCN) and is typically caused by entrapment as the nerve passes deep to the inguinal ligament. This sensory mononeuropathy is rare in children and diagnosis is typically delayed, often leading to prolonged functional impairment and unnecessary medical testing. A 9-year-old girl presented to the pain clinic with a 6-week history of right anterolateral thigh pain first noticed after a nontraumatic cheerleading practice. Comprehensive laboratory and radiographic evaluation by multiple prior specialists revealed no clear nociceptive source of pain. History and examination were consistent with a diagnosis of idiopathic, compressive meralgia paresthetica. Conservative management including physical therapy was followed for 2 weeks with only mild improvement noted. To facilitate physical therapy, an ultrasound-guided LFCN block was performed which confirmed the diagnosis by providing complete analgesia. The patient reported overall 25% improvement from multimodal therapy at another 2 weeks. A second LFCN block was performed with complete resolution of symptoms and restoration of function. The patient remains pain-free and has returned to walking, running, and competitive sports. The primary goal of pediatric chronic pain management, regardless of pain etiology, is early restoration of function to avoid prolonged absence from school, sports, or other productive activities and limit the psychological burden of chronic disease. AD - Monroe Carell Jr Children's Hospital at Vanderbilt, 2200 Children's Way, Suite 3115, Nashville, TN 37232 AN - 117587800. Language: English. Entry Date: 20161223. Revision Date: 20190223. Publication Type: journal article AU - Franklin, Andrew D. AU - Cierny, G. Bennett AU - Luckett, Twila R. DB - cin20 DO - 10.1016/j.jclinane.2016.04.015 DP - EBSCOhost KW - Pain -- Therapy Nerve Compression Syndromes -- Rehabilitation Nerve Compression Syndromes -- Pathology Femoral Nerve Femoral Nerve -- Pathology Physical Therapy Combined Modality Therapy Female Child Treatment Outcomes Ultrasonography Nerve Block -- Methods Clinical Assessment Tools N1 - case study. Journal Subset: Biomedical; Peer Reviewed; USA. Instrumentation: Sensory Integration and Praxis Tests (SIPT) (Ayres); Functional Living Index: Cancer (FLIC) (Schipper et al). NLM UID: 8812166. PMID: NLM27555210. PY - 2016 SN - 0952-8180 SP - 456-459 ST - Interventional and multimodal pain rehabilitation in a child with meralgia paresthetica T2 - Journal of Clinical Anesthesia TI - Interventional and multimodal pain rehabilitation in a child with meralgia paresthetica UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=117587800&site=ehost-live&scope=site VL - 33 ID - 394 ER - TY - JOUR AB - im: Health literacy (HL) is a key outcome of health education. Low HL is associated with a higher risk of health-related impairments and high health-related costs. This article therefore describes the contents and evaluation of the school-based programme 'Health literacy in school-aged children' (GeKo) and its acceptance by teachers. A second focus of the study is the description of methods to increase the response of schools, students and parents as a crucial condition for the validity and generalizability of results from epidemiologic prevention studies. Subjects and methods: The evaluation of the prevention program GeKo included 5th grade students aged 9-13 years in schools in the region of Greifswald and East Pomerania [longitudinal randomised control group pre-post design (RCT)]. Data collections took place within the extended school dentist examination visits at the beginning of the 2007/2008 school year and at the beginning of the second half term of the 2008/2009 school year. This included medical examinations and self-completion questionnaires of students, parents and teachers. The study was authorised by the data protection commissioner of Mecklenburg-West Pomerania, the Ministry of Education, Science and Culture of Mecklenburg-West Pomerania and the Ethics Commitee of the Ernst Moritz Arndt University Greifswald. Based on the authorisation of the data protection concept and concerns about selective response, parents were not granted a consent but rather a right to refuse participation. In order to attain a high participation rate of the schools, the school principals were informed about the research project by an invitation letter, telephone calls and personal visits. Additionally an agreement on participation was handed out to all schools as a binding criterion for participation. By signing this agreement schools committed to using the offered teaching material, to participate in teacher training and evaluation, and to provide resources with respect to time and space. At the beginning of the 2007/2008 school year, all parents of 5th grade students were informed about the research project, the prevention programme and aspects of data protection. In order to increase the response rate parents also received a supporting letter from the Minister of Education, Science and Culture of Mecklenburg-West Pomerania, which mainly provided information about the importance of the research project and asked for support of this study. Results: In Greifswald/East Pomerania, 19 of 22 schools with 5th year classes participated in GeKo (response rate: 86.3%). Out of 914 eligible students in the participating schools, 882 children (96.4%) took part in the school dentist examinations. A total of 863 children (94.4%) participated in the extended school dentist examination; 852 children (93.2%) took part in the student survey. In the parental survey 721 parents participated (response rate: 78.8%). A high level of acceptance referring to teacher training and the appropriateness of the GeKo programme was achieved. Conclusion: As shown by the low rate of refusal, the programme and the evaluation study were well accepted. Possible reasons for these results could be the chosen procedure of establishing contact with schools before sending the questionnaires and the parent's right to refuse their child's participation instead of giving an active confirmation. Because of this high response rate, the database enables comprehensive conclusions to be reached on the health-related state of students in Greifswald/East Pomerania. AD - Institute for Community Medicine, Department Epidemiology of Health Care and Community Health, University of Greifswald, Ellernholzstr. 1-2 17487 Greifswald Germany Institute for Community Medicine, Department Methods of Community Medicine, University of Greifswald, Greifswald Germany Institute for Human Nutrition and Food Studies, University of Kiel, Kiel Germany Preventive and Pediatric Dentistry, University of Greifswald, Greifswald Germany AN - 62658937. Language: English. Entry Date: 20110902. Revision Date: 20120731. Publication Type: Article AU - Franze, Marco AU - Fendrich, Konstanze AU - Schmidt, Carsten AU - Fahland, Ruth AU - Thyrian, Jochen AU - Plachta-Danielzik, Sandra AU - Seiberl, Jasmin AU - Hoffmann, Wolfgang AU - Splieth, Christian DB - cin20 DO - 10.1007/s10389-011-0421-7 DP - EBSCOhost IS - 4 KW - Health Knowledge School Health Education Program Implementation Program Evaluation Health Promotion Attitude to Health Human Child Adolescence Male Female Germany Questionnaires Teaching Materials School Health Services Faculty Development Dental Health Education Immunization -- Education Smoking -- Education Chronic Pain -- Education Obesity -- Education Physical Activity -- Education Nutrition Education Seminars and Workshops Body Weights and Measures Dental Care for Children Parental Attitudes Faculty Attitudes Outcomes of Education Funding Source N1 - research; tables/charts. Journal Subset: Continental Europe; Europe; Peer Reviewed; Public Health. Special Interest: Public Health. Grant Information: Federal Ministry of Education and Research Germany (grant no. 01EL0610).. NLM UID: 9425271. PY - 2011 SN - 0943-1853 SP - 339-347 ST - Implementation and evaluation of the population-based programme "health literacy in school-aged children" (GeKo) T2 - Journal of Public Health (09431853) TI - Implementation and evaluation of the population-based programme "health literacy in school-aged children" (GeKo) UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=62658937&site=ehost-live&scope=site VL - 19 ID - 577 ER - TY - JOUR AB - Objective Pain, fear, and fainting management during school-based vaccinations is suboptimal. The objective was to examine stakeholder perceptions of barriers and facilitators to better practices. Method: Six semi-structured focus groups were conducted in Niagara Region, Ontario: two parent groups (n=7); one grade 7 to 8 student group (n=9); two nurse groups (n=12); and one school staff group (n=6). Participants shared perceptions about school vaccination clinics and the implementation of specific strategies and tools. Focus groups were audio recorded and transcribed. The Consolidated Framework for Implementation Research (CFIR) was used as the framework for analysis. Results Feedback from stakeholders was categorized into four domains of CFIR: intervention characteristics, inner setting, outer setting, and characteristics of individuals. Intervention characteristics included: vaccine educational materials, vaccination accommodations, distraction techniques, topical anaesthetics, and food. Inner setting factors included: school vaccination procedures, relationships between school staff and nurses, assessment and documentation of student fear, and factors that contribute to a chaotic vaccination clinic. Outer setting factors were: the social environment and addressing parent and student needs. Stakeholder roles were discussed in characteristics of individuals. Conclusion This study identified elements that can facilitate and challenge pain and fear mitigation tools and strategies; these elements should be considered in the development of a Knowledge Translation (KT) intervention to improve the school vaccination experience. AD - Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario University of Guelph, Guelph, Ontario Dalhousie University, Halifax, Nova Scotia Niagara Region Public Health & Emergency Services, Thorold, Ontario AN - 135663309. Language: English. Entry Date: 20190404. Revision Date: 20190507. Publication Type: Article AU - Freedman, Tamlyn AU - Taddio, Anna AU - Wong, Horace AU - McMurtry, C. Meghan AU - MacDonald, Noni AU - McDowall, Tori AU - deVlaming-Kot, Christene AU - Alderman, Leslie DB - cin20 DO - 10.1093/pch/pxz017 DP - EBSCOhost KW - Stakeholder Participation -- Psychosocial Factors Health Services Accessibility Attitude to Vaccines Knowledge Management Human Focus Groups Ontario Parents Nurses Students Audiorecording Pain Fear Syncope School Health Services N1 - research; tables/charts. Supplement Title: 2019 Supplement. Journal Subset: Biomedical; Canada. NLM UID: 9815960. PY - 2019 SN - 1205-7088 SP - S19-S28 ST - Involving stakeholders in informing the development of a Knowledge Translation (KT) intervention to improve the vaccination experience at school T2 - Paediatrics & Child Health (1205-7088) TI - Involving stakeholders in informing the development of a Knowledge Translation (KT) intervention to improve the vaccination experience at school UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=135663309&site=ehost-live&scope=site VL - 24 ID - 249 ER - TY - JOUR AB - Objective: To analyse trends in dental pain prevalence among Brazilian adolescent students over 6 years, focusing on inequalities by maternal education. Methods: Data from the National Adolescent School‐Based Health Survey (PeNSE) carried out in 2009 (n = 45 239), 2012 (n = 46 482) and 2015 (n = 35 592) were analysed, including ninth grade students from the 27 state capitals in Brazil who were of ages 11‐17 years or older. Variables analysed were dental pain within the last 6 months (yes/no) and the following sociodemographic factors: age, sex, race, type of school and maternal schooling (years of study: ≤8; 9‐11; ≥12). The prevalence of dental pain in the 3 years was compared using the Rao‐Scott test. Relative and absolute measures of socioeconomic (maternal education) inequalities in dental pain were applied using the slope index of inequality (SII) and the relative concentration index (RCI). Results: The prevalence of dental pain increased from 17.5% (95% CI = 16.9‐18.2) in 2009 to 20.4% (95% CI = 19.7‐21.1) in 2012, then to 21.8% (95% CI = 21.1‐22.5) in 2015. All sociodemographic factors investigated were associated with dental pain in all survey years. There was an increasing proportion of the outcome in all categories of maternal education over the years studied. Absolute (SII) and relative (RCI) inequalities regarding of maternal education were found; these indicate higher levels of dental pain in the lower socioeconomic group in each study year. However, no significant changes in inequalities were found from 2009 to 2015. Conclusions: The prevalence of dental pain increased in the 2009‐2012 and 2012‐2015 periods, and social inequalities were found. Higher levels of dental pain persisted in the lower maternal education group. Inequalities remained stable over time. Broader actions to reduce the existing inequalities are needed and should be a priority for public policies. AD - School of Dentistry, Federal University of Goiás, Goiânia‐GO Brazil Menzies Health Institute Queensland and School of Dentistry and Oral Health, Griffith University, Gold Coast‐QLD Queensland, Australia School of Dentistry, Federal University of Minas Gerais, Belo Horizonte‐MG Brazil AN - 139546813. Language: English. Entry Date: 20191111. Revision Date: 20201130. Publication Type: Article AU - Freire, Maria C. M. AU - Jordão, Lidia M. R. AU - Peres, Marco A. AU - Abreu, Mauro H. N. G. DB - cin20 DO - 10.1111/cdoe.12483 DP - EBSCOhost IS - 6 KW - Toothache -- Trends -- In Adolescence Toothache -- Epidemiology -- Brazil Mothers -- Psychosocial Factors Educational Status Human Male Female Adolescence Brazil Socioeconomic Factors Descriptive Statistics Confidence Intervals Surveys Scales Funding Source Health Status Disparities N1 - research; tables/charts. Journal Subset: Biomedical; Continental Europe; Europe; Peer Reviewed; Public Health. Instrumentation: Slope Index of Inequality (SII); Relative Concentration Index (RCI). Grant Information: Ministério da Saúde, Grant/Award Number: Financed the National School-Based Health Survey; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), Brazil, Grant/Award Number: Finance Code 001. NLM UID: 0410263. PY - 2019 SN - 0301-5661 SP - 454-460 ST - Six‐year trends in dental pain and maternal education inequalities among Brazilian adolescents T2 - Community Dentistry & Oral Epidemiology TI - Six‐year trends in dental pain and maternal education inequalities among Brazilian adolescents UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=139546813&site=ehost-live&scope=site VL - 47 ID - 208 ER - TY - JOUR AB - This study assessed the utility of the Multidimensional Patient Impression of Change (MPIC) questionnaire in a pediatric pain population after interdisciplinary treatment. Observational study with retrospective chart review. The observed treatment program included psychological counseling, relaxation training, physical therapy, occupational therapy, and physician management. Outpatient pain management center affiliated with an academic rehabilitation hospital. A heterogeneous group of pediatric patients with chronic pain (N=202) who completed an interdisciplinary pain management program. Not applicable. Measures assessing pain, mood, development, social functioning, physical functioning, and family functioning were administered pre- and posttreatment, and the MPIC was administered posttreatment. Statistically significant improvements were observed in all outcomes (P <.05). The majority of patients perceived themselves to be improved (minimally to very much) in all clinical domains of the MPIC, ranging from 60% (medication efficacy) to 96% (coping with pain). The MPIC ratings were significantly correlated with improvements in most of the outcome measures. The MPIC domains accounted for more than half of the unique variance in predictive models when added to the Patient Global Impression of Change, and most of the variance when added to the models first. The MPIC was found to be an effective screening tool for assessing patient perceived progress in a pediatric chronic pain population. AD - Pain Management Center, Shirley Ryan AbilityLab, Chicago, IL Department of Physical Medicine & Rehabilitation, Northwestern University Feinberg School of Medicine, Chicago, IL AN - 146013077. Language: English. Entry Date: 20201005. Revision Date: 20201005. Publication Type: Article AU - Gagnon, Christine M. AU - Scholten, Paul AU - Amstutz, Diane AU - Henderson, Lauren AU - Revivo, Gadi DB - cin20 DO - 10.1016/j.apmr.2020.06.015 DP - EBSCOhost IS - 10 KW - Chronic Pain -- Therapy -- In Infancy and Childhood Pain Management -- Methods -- In Infancy and Childhood Instrument Validation Questionnaires -- Evaluation Psychometrics -- Evaluation Outcome Assessment Human Child Adolescence Validation Studies Nonexperimental Studies Prospective Studies Retrospective Design Record Review Internal Consistency Coefficient Alpha Pearson's Correlation Coefficient Linear Regression Male Female Factor Analysis Patient Attitudes Treatment Outcomes N1 - research; tables/charts. Journal Subset: Allied Health; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Instrumentation: Multidimensional Patient Impression of Change (MPIC); Bath Adolescent Pain Questionnaire (BAPQ). NLM UID: 2985158R. PY - 2020 SN - 0003-9993 SP - 1771-1779 ST - Psychometric Properties of the Multidimensional Impression of Change in a Cohort of Pediatric Patients With Pain T2 - Archives of Physical Medicine & Rehabilitation TI - Psychometric Properties of the Multidimensional Impression of Change in a Cohort of Pediatric Patients With Pain UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=146013077&site=ehost-live&scope=site VL - 101 ID - 166 ER - TY - JOUR AB - In this study, we measured the health-related quality of life (HRQOL) and fatigue of the children of health professionals, aged between two and eleven years, and assessed the daytime and sleep habits of these children and their parents. The study included children from a public school. Data regarding demographics and daily habits were collected. The HRQOL, sleep habits and fatigue were measured using questionnaires. A total of 249 parents participated - 63.5% reported getting an adequate amount of sleep, while 47.4% woke up feeling tired. The children's mean age was 5.6 years - 62.2% watched television in their rooms, 50% used the computer (> 4 hours/day) and 27.8% engaged in extracurricular physical exercise. The sleep score was 45.8 ± 12.2. The HRQOL scores were higher in the physical and lower in the emotional aspects. We found that poorer sleep on the part of both children and parents may be related to the children's lower HRQOL. We conclude that the inadequate habits of parents as well as children, are related to a decrease in HRQOL, particularly regarding the emotional aspect. AN - 107992822. Language: Portuguese. Entry Date: 20130419. Revision Date: 20150820. Publication Type: Journal Article AU - Gamallo, Silvia Maria Moussi AU - Caparroz, Fábio AU - Terreri, Maria Teresa Ramos Ascensão AU - Hilário, Maria Odete Esteves AU - Len, Claudio Arnaldo DB - cin20 DO - dx.doi.org/S0080-62342012000600005 DP - EBSCOhost IS - 6 KW - Child Health Fatigue -- In Infancy and Childhood Health Personnel Parents Quality of Life -- In Infancy and Childhood Sleep -- In Infancy and Childhood Brazil Child Child, Preschool Chronic Disease Chronic Pain Cross Sectional Studies Descriptive Statistics Employment Status Female Field Studies Human Infant Kruskal-Wallis Test Life Style, Sedentary Male Marital Status Parity Physical Activity Questionnaires Scales Schools Spearman's Rank Correlation Coefficient Students Summated Rating Scaling T-Tests N1 - research; tables/charts. Journal Subset: Double Blind Peer Reviewed; Expert Peer Reviewed; Mexico & Central/South America; Nursing; Peer Reviewed. Special Interest: Pediatric Care. Instrumentation: Pediatric Quality of Life Inventory (PEDSQL). NLM UID: 0242726. PMID: NLM23380772. PY - 2012 SN - 0080-6234 SP - 1313-1319 ST - Health-related quality of life of the children of health professionals T2 - Revista da Escola de Enfermagem da USP TI - Health-related quality of life of the children of health professionals UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=107992822&site=ehost-live&scope=site VL - 46 ID - 541 ER - TY - JOUR AB - Objective: In light of the recent uptrend in the prescription of opioids, this study seeks to identify patterns of opioid misuse among orthopaedic postoperative patients and principal external sources in obtaining these medications.Design: Ten-month survey-based study.Setting: Two Level I trauma centers (urban and suburban).Patients/participants: Two hundred seven patients between the ages of 18 and 89 years who underwent surgical fixation of fractures involving the pelvis, long bones, or periarticular regions of the knee, ankle, elbow, and wrist.Main Outcome Measurements: Patients who believed they were undermedicated, used prescribed opioids at higher than recommended doses, and took extra opioids in addition to their prescribed analgesics were analyzed by age, employment, income, education, controlled substance use, pain interference with activities of daily living, and anatomic surgical site.Results: One hundred eighty-two patients completed the survey; 19.2% of patients (n = 35) felt undermedicated [unemployed (P < 0.05), low income (P < 0.05), and self-reported controlled substance users (P < 0.05)]; 12.6% of patients (n = 23) admitted to using pain medications at a higher dose than prescribed [unemployed (P < 0.05), lower income (P < 0.05), nonhigh school graduates (P < 0.05), and previous controlled substance users (P < 0.05)]; 9.3% (n = 17) admitted to using external opioids [unemployed patients (P < 0.05) and self-reported controlled substance users (P < 0.05)]. Major sources of extraneous opioids include family/friends (n = 5) and other doctors (n = 4).Conclusion: Unemployed and lower-income patients were significantly more likely to believe that their surgeon was not prescribing them enough pain medications as well as use their prescribed opioid medications at a higher than recommended dose compared with their employed counterparts with higher incomes. Unemployed patients were also significantly more likely to use additional opioid analgesics in addition to those prescribed to them by their primary surgeon. Surgeon awareness of a patient's socioeconomic background and associated risk of opioid misuse is crucial to prescribe the safest most effective pain regimen.Level Of Evidence: Prognostic Level IV. See Instructions for Authors for a complete description of levels of evidence. AD - Department of Orthopaedic Surgery, St. Luke's University Health Network, Bethlehem, PA Temple-St. Luke's University School of Medicine, Bethlehem, PA Temple University School of Medicine, Philadelphia, PA Department of Orthopaedic Surgery, Temple University Hospital, Philadelphia, PA AN - 122021631. Language: English. Entry Date: 20171115. Revision Date: 20171115. Publication Type: journal article AU - Gangavalli, Anup AU - Malige, Ajith AU - Terres, George AU - Rehman, Saqib AU - Nwachuku, Chinenye DB - cin20 DO - 10.1097/BOT.0000000000000741 DP - EBSCOhost IS - 4 KW - Postoperative Pain -- Prevention and Control Postoperative Pain -- Epidemiology Self Medication -- Statistics and Numerical Data Analgesics, Opioid -- Therapeutic Use Substance Use Disorders -- Epidemiology Female Adolescence Young Adult Substance Use Disorders -- Diagnosis Pain Measurement -- Statistics and Numerical Data Income Educational Status Postoperative Pain -- Diagnosis Pennsylvania Aged, 80 and Over Aged Pain Measurement Middle Age Employment Adult Human Chronic Pain Male Clinical Trials Validation Studies Comparative Studies Evaluation Research Multicenter Studies N1 - clinical trial; research. Journal Subset: Allied Health; Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Evidence-Based Practice. NLM UID: 8807705. PMID: NLM28323765. PY - 2017 SN - 0890-5339 SP - e103-e109 ST - Misuse of Opioids in Orthopaedic Postoperative Patients T2 - Journal of Orthopaedic Trauma TI - Misuse of Opioids in Orthopaedic Postoperative Patients UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=122021631&site=ehost-live&scope=site VL - 31 ID - 367 ER - TY - JOUR AB - Purpose: The aim of this retrospective analysis of spinal fusion, was to document the clinical, functional, and radiological outcomes with a local bone graft plus the highly osteoconductive hydroxyapatite, bio-derived Orthoss®, with or without bone marrow aspirate.Methods: Forty seven patients submitted to spinal posterolateral fusion were operated for four major indications: scoliosis in young patients (11), degenerative spine (18), lumbosacral transitional anomalies in young adults (14), and spine trauma (four). Sixteen patients had more than four levels fused. In addition to spinal decompression and instrumented fusion, autologous bone grafts from the excised lamina were augmented with Orthoss® granules in a 1:1 ratio. In addition iliac crest bone marrow aspirate was used in 70 % of the patients. The results were assessed clinically in terms of pain, and return to school or professional activities were checked at three, six, and 12 months following surgery with a mean follow-up of 20 months. In scoliotic patients, correction of the major angle was evaluated from one to four years after surgery.Results: Pain persistence was reported only in four cases, after three months after surgery. A functional recovery was noted in almost all patients groups within these three months. Progressive bone formation with evidence of bone fusion masses were already observed at six months. No fusion failure was observed.Conclusions: Local bone enhanced by an osteoconductive long-term stable scaffold, used with and without bone marrow aspirate, led to successful fusion in all patients by six months while functional recovery was reported already within three to six months. AD - Capio Polyclinique du Beaujolais , 120 ancienne route de Beaujeu 69653 Villefranche sur Saône Cedex France AN - 117522548. Language: English. Entry Date: 20180403. Revision Date: 20190402. Publication Type: journal article. Journal Subset: Biomedical AU - Garin, Christophe AU - Boutrand, Séverine DB - cin20 DO - 10.1007/s00264-016-3140-4 DP - EBSCOhost IS - 9 KW - Spinal Fusion Bone Substitutes Bone Transplantation Minerals Spine Middle Age Female Retrospective Design Lumbar Vertebrae Male Scoliosis -- Surgery Adolescence Spinal Injuries -- Surgery Adult Young Adult Treatment Outcomes Aged Clinical Assessment Tools Scales N1 - Continental Europe; Europe; Peer Reviewed. Instrumentation: Clinical Decision Making in Nursing Scale (CDMNS) (Jenkins); Functional Living Index: Cancer (FLIC) (Schipper et al). NLM UID: 7705431. PMID: NLM26961192. PY - 2016 SN - 0341-2695 SP - 1875-1882 ST - Natural hydroxyapatite as a bone graft extender for posterolateral spine arthrodesis T2 - International Orthopaedics TI - Natural hydroxyapatite as a bone graft extender for posterolateral spine arthrodesis UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=117522548&site=ehost-live&scope=site VL - 40 ID - 392 ER - TY - JOUR AB - Many children and adolescents experience recurrent pain, but only a few become disabled by it. Research has established that higher pain intensity and worse depression seem to predict poorer functioning in this population. Parent and family variables have been minimally researched. This study investigated functional disability, social/adaptive functioning and school attendance in a population of highly disabled adolescents and their parents seeking help for chronic pain. Adolescents (N=110) were assessed using the Bath Adolescent Pain Questionnaire [BAPQ; Eccleston C, Jordan A, McCracken LM, Sleed M, Connell H, Clinch J. The Bath Adolescent Pain Questionnaire (BAPQ): Development and preliminary psychometric evaluation of an instrument to assess the impact of chronic pain on adolescents. Pain 2005;118:263-70], a multidimensional instrument designed for a pain population. Pain intensity and depression predicted functional disability. However, social/adaptive functioning was associated with different variables, including parent factors, and school attendance showed no association with pain intensity or anxiety. The results emphasise the need to measure multiple domains of functioning, and show that the connections between pain, physical disability and adaptive functioning are looser than might be predicted. AD - Pain Management Unit, Royal National Hospital for Rheumatic Diseases and The University of Bath, BA1 1RL, UK. jeremy.gauntlett-gilbert@rnhrd-tr.swest.nhs.uk AN - 104745786. Language: English. Entry Date: 20110610. Revision Date: 20200708. Publication Type: journal article AU - Gauntlett-Gilbert, Jeremy AU - Eccleston, Christopher DB - cin20 DO - 10.1016/j.pain.2006.12.021 DP - EBSCOhost IS - 1/2 KW - Activities of Daily Living Depression -- Epidemiology Depression -- Psychosocial Factors Pain -- Epidemiology Pain -- Psychosocial Factors Risk Assessment -- Methods Sickness Impact Profile Adolescence Adolescent Psychology Chronic Disease Disability Evaluation Female Great Britain Human Incidence Male Questionnaires Risk Factors Social Adjustment N1 - research. Journal Subset: Biomedical; Continental Europe; Europe; Peer Reviewed. NLM UID: 7508686. PMID: NLM17267129. PY - 2007 SN - 0304-3959 SP - 132-141 ST - Disability in adolescents with chronic pain: Patterns and predictors across different domains of functioning T2 - PAIN TI - Disability in adolescents with chronic pain: Patterns and predictors across different domains of functioning UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104745786&site=ehost-live&scope=site VL - 131 ID - 706 ER - TY - JOUR AB - Background The health of a carer is a key factor which can affect the well-being of the child with disabilities for whom they care. In low-income countries, many carers of children with disabilities contend with poverty, limited public services and lack assistive devices. In these situations caregiving may require more physical work than in high-income countries and so carry greater risk of physical injury or health problems. There is some evidence that poverty and limited access to health care and equipment may affect the physical health of those who care for children with disabilities. This study seeks to understand this relationship more clearly. Methods A mixed methods study design was used to identify the potential physical health effects of caring for a child with moderate-severe motor impairments in Kilifi, Kenya. Qualitative data from in-depth interviews were thematically analysed and triangulated with data collected during structured physiotherapy assessment. Results Carers commonly reported chronic spinal pain of moderate to severe intensity, which affected essential activities. However, carers differed in how they perceived their physical health to be affected by caregiving, also reporting positive benefits or denying detrimental effects. Carers focussed on support in two key areas; the provision of simple equipment and support for their children to physically access and attend school. Conclusions Carers of children with moderate-severe motor impairments live with their own physical health challenges. While routine assessments lead to diagnosis of simple musculoskeletal pain syndromes, the overall health status and situation of carers may be more complex. As a consequence, the role of rehabilitation therapists may need to be expanded to effectively evaluate and support carers' health needs. The provision of equipment to improve their child's mobility, respite care or transport to enable school attendance is likely to be helpful to carers and children alike. AD - Faculty of Medicine and Health Sciences, University of East Anglia, Norwich Centre for Geographic Medicine Research (Coast), Kenya Medical Research Institute Physiotherapy Department, Kilifi District Hospital, Kilifi, Kenya, and Centre for Geographic Medicine Research (Coast), Kenya Medical Research Institute; Neuroscience Unit, Institute of Child Health, University College London, London Faculty of Medicine and Health Sciences, University of East Anglia, Norwich; Department of Psychiatry, University of Oxford, Oxford, UK; Faculty of Health, University of Sydney, Sydney, NSW, Australia AN - 104266955. Language: English. Entry Date: 20130412. Revision Date: 20200708. Publication Type: Journal Article AU - Geere, J. L. AU - Gona, J. AU - Omondi, F. O. AU - Kifalu, M. K. AU - Newton, C. R. AU - Hartley, S. DB - cin20 DO - 10.1111/j.1365-2214.2012.01398.x DP - EBSCOhost IS - 3 KW - Parents of Disabled Children -- Kenya Health Status -- Kenya Caregivers -- Kenya Human Kenya Funding Source Child Health Qualitative Studies Interviews Thematic Analysis Triangulation Back Pain Attitude to Health Assistive Technology Devices Transportation Quantitative Studies International Classification of Functioning, Disability, and Health Purposive Sample Structured Interview Child, Preschool Adolescence Child Adolescent Health Young Adult Adult Middle Age Aged Descriptive Statistics Male Female Physical Therapy Assessment Data Analysis Software Coding Chronic Pain Child, Disabled N1 - research; tables/charts. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Pediatric Care. Grant Information: Funded by the CP Charitable trust UK.. NLM UID: 7602632. PMID: NLM22823515. PY - 2013 SN - 0305-1862 SP - 381-392 ST - Caring for children with physical disability in Kenya: potential links between caregiving and carers' physical health T2 - Child: Care, Health & Development TI - Caring for children with physical disability in Kenya: potential links between caregiving and carers' physical health UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104266955&site=ehost-live&scope=site VL - 39 ID - 523 ER - TY - JOUR AB - Objective: To investigate whether later high school start time is associated with lower migraine frequency in high school students with migraine. Background: Adequate sleep is thought to be important in managing adolescent migraine. The American Academy of Sleep Medicine recommends teenagers sleep ≥8 hours/night. Adolescents have a physiologically delayed sleep phase, going to bed, and waking later than children and adults. The American Academy of Pediatrics (AAP) accordingly recommends high schools start no earlier than 8:30 AM. Methods: Cross‐sectional observational study of U.S. high schoolers with migraine. Participants were recruited nationally using social media. Respondents attending high schools starting at 8:30 AM or later were compared to those attending earlier start time schools. The primary outcome was headache days/month. Results: Two hundred and fifty‐six subjects constituted the analysis set: 115 later group vs 141 earlier group. Age and sex did not differ. Mean (SD) self‐reported headache days/month were 7 (5) vs 8 (7), respectively, (P = .985); mean difference (95% CI for the difference) was −0.8 (−2.3‐0.7) days. Median (IQR) self‐reported total hours of sleep/school night were: 5.6 (5.0‐6.6) vs 5.6 (4.5‐6.4), P = .058. Students attending later start time schools woke later (median [IQR] 6:38 AM [55 minutes] vs 6:09 AM [59 minutes], P < .0001) and left home later (median [IQR] 7:28 AM [28 minutes] vs 7:02 AM [60 minutes], P < .0001). Average commute time was also longer: 41 (21) minutes vs 28 (16), P < .0001. The vast majority in both groups reported missing breakfast at least once/week: 103/114 (90.4%) vs 128/141 (90.8%), P = .907. Hours of sleep did not correlate with headache days per month. Conclusion: High school start time does not have a large effect on headache frequency in high schoolers with migraine. Given the high variance in headache days/month observed in this study, a larger study would be needed to determine whether there might still be a small effect of starting high school at/after 8:30 AM. More research is needed to establish evidence‐based recommendations about lifestyle factors in adolescent migraine management. AD - Department of Neurology, University of California, San Francisco, San Francisco CA, USA Department of Neurology, Stanford University Hospital and Clinics, Palo Alto CA, USA Division of Neurology, Children's Hospital of Philadelphia, Philadelphia PA, USA Departments of Neurology & Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia PA, USA Department of Epidemiology & Biostatistics, University of California, San Francisco, San Francisco CA, USA AN - 137436467. Language: English. Entry Date: 20190715. Revision Date: 20200630. Publication Type: Article AU - Gelfand, Amy A. AU - Pavitt, Sara AU - Greene, Kaitlin AU - Szperka, Christina L. AU - Irwin, Samantha AU - Grimes, Barbara AU - Allen, Isabel E. DB - cin20 DO - 10.1111/head.13535 DP - EBSCOhost IS - 7 KW - Migraine -- Prevention and Control -- In Adolescence Time Factors School Policies -- United States Students, High School -- Psychosocial Factors -- United States Human Cross Sectional Studies Nonexperimental Studies Adolescence Social Media Self Report Disease Duration Breakfast United States Confidence Intervals Migraine -- Therapy Sleep -- Evaluation N1 - research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 2985091R. PY - 2019 SN - 0017-8748 SP - 1024-1031 ST - High School Start Time and Migraine Frequency in High School Students T2 - Headache: The Journal of Head & Face Pain TI - High School Start Time and Migraine Frequency in High School Students UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=137436467&site=ehost-live&scope=site VL - 59 ID - 229 ER - TY - JOUR AB - Objective: To determine whether high school start time is associated with headache frequency in adolescents with migraine. Background: Adolescence is marked by a physiologic delayed circadian phase, characterized by later bedtimes and wake times. The American Academy of Pediatrics (AAP) recommends that high schools start no earlier than 8:30 a.m., but most high schools in the United States start earlier. The study hypothesis was that adolescents with migraine whose high schools start at 8:30 a.m. or later (late group) would have lower headache frequency than those whose schools start earlier than 8:30 a.m. (early group). Methods: This was a cross‐sectional Internet survey study of US high schoolers with migraine recruited online through social media. Comparisons were made between the late group and the early group. The primary outcome measure was self‐reported headache days/month. Results: In total, 1012 respondents constituted the analytic set: n = 503 in the late group versus n = 509 in the early group. Mean (SD) self‐reported headache days/month was 4.8 (4.6) versus 7.7 (6.1) in the late and early groups, respectively (p < 0.001); mean difference −2.9 (95% CI −2.2 to −3.6). Mean (SD) self‐reported hours of sleep on a school night was 7.9 (0.9) versus 6.9 (1.3), p < 0.001. Adjusting for total hours of sleep, sex, taking a migraine preventive, days of acute medication use, hours of homework, grade level, and missing breakfast, mean (SD) self‐reported headache days/month remained lower in the late group than in the early group: 5.8 (95% CI 5.3–6.2) versus 7.1 (95% CI 6.7–7.4), (p < 0.001); mean difference −1.3 (95% CI −1.9 to −0.7). Conclusion: Adolescents with migraine who attend high schools that follow AAP recommendations for start times have lower self‐reported headache frequency than those whose high schools start before 8:30 a.m. If prospective studies confirm this finding, shifting to a later high school start time may be an effective strategy for migraine prevention in adolescents. AD - Child & Adolescent Headache Program, University of California, San Francisco, San Francisco CA,, USA Division of Neurology, Children's Hospital of Philadelphia & Department of Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia PA,, USA Division of Neurology, Children's Hospital of Philadelphia & Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia PA,, USA Division of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston MA,, USA Department of Epidemiology & Biostatistics, University of California, San Francisco, San Francisco CA,, USA Research Institute, California Pacific Medical Center, San Francisco CA,, USA Academic Research Systems, University of California, San Francisco, San Francisco CA,, USA AN - 148996383. Language: English. Entry Date: 20210305. Revision Date: 20210311. Publication Type: Article AU - Gelfand, Amy A. AU - Pavitt, Sara AU - Ross, Alexandra C. AU - Szperka, Christina L. AU - Irwin, Samantha L. AU - Bertisch, Suzanne AU - Stone, Katie L. AU - Frazier, Remi AU - Grimes, Barbara AU - Allen, I. Elaine DB - cin20 DO - 10.1111/head.14016 DP - EBSCOhost IS - 2 KW - Migraine -- Epidemiology -- United States Students, High School -- Psychosocial Factors -- In Adolescence Schools, Secondary Time Factors Sleep Human United States Adolescence Cross Sectional Studies Comparative Studies Descriptive Statistics Confidence Intervals Self Report N1 - research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 2985091R. PY - 2021 SN - 0017-8748 SP - 343-350 ST - Later high school start time is associated with lower migraine frequency in adolescents T2 - Headache: The Journal of Head & Face Pain TI - Later high school start time is associated with lower migraine frequency in adolescents UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=148996383&site=ehost-live&scope=site VL - 61 ID - 149 ER - TY - JOUR AB - Background: We recently showed headache to be common in children (aged 7–11 years) and adolescents (aged 12–17) in Lithuania. Here we provide evidence from the same study of the headache-attributable burden. Methods: Following the generic protocol for Lifting The Burden's global schools-based study, this cross-sectional survey administered self-completed structured questionnaires to pupils within classes in 24 nationally representative schools selected from seven regions of the country. Headache diagnostic questions were based on ICHD-3 beta criteria but for the inclusion of undifferentiated headache (UdH; defined as mild headache with usual duration < 1 h). Burden enquiry was conducted in multiple domains. Results: Questionnaires were completed by 2505 pupils (1382 children, 1123 adolescents; participating proportion 67.4%), of whom 1858 reported headache in the preceding year, with mean frequency (±SD) of 3.7 ± 4.5 days/4 weeks and mean duration of 1.6 ± 1.9 h. Mean proportion of time in ictal state, estimated from these, was 0.9% (migraine 1.5%, probable medication-overuse headache [pMOH] 10.9%). Mean intensity on a scale of 1–3 was 1.6 ± 0.6 (mild-to-moderate). Symptomatic medication was consumed on 1.5 ± 2.8 days/4 weeks. Lost school time was 0.5 ± 1.5 days/4 weeks (migraine 0.7 ± 1.5, pMOH 5.0 ± 7.8) based on recall, but about 50% higher for migraine according to actual absences recorded in association with reported headache on the preceding day. More days were reported with limited activity (overall 1.2 ± 2.4, migraine 1.5 ± 2.2, pMOH 8.4 ± 8.5) than lost from school. One in 30 parents (3.3%) missed work at least once in 4 weeks because of their son's or daughter's headache. Emotional impact and quality-of-life scores generally reflected other measures of burden, with pMOH causing greatest detriments, followed by migraine and tension-type headache, and UdH least. Burdens were greater in adolescents than children as UdH differentiated into adult headache types. Conclusions: Headache in children and adolescents in Lithuania is mostly associated with modest symptom burden. However, the consequential burdens, in particular lost school days, are far from negligible for migraine (which is prevalent) and very heavy for pMOH (which, while uncommon in children, becomes four-fold more prevalent in adolescents). These findings are of importance to both health and educational policies in Lithuania. AD - Department of Neurology, Faculty of Medicine, Lithuanian University of Health Sciences, Kaunas, Lithuania Department of Preventive Medicine and Health Research Institute, Faculty of Public Health, Lithuanian University of Health Sciences, Kaunas, Lithuania Department of Public Health, Mersin University School of Medicine, Mersin, Turkey Neurology Department, Cerrahpaşa School of Medicine, Istanbul University, Istanbul, Turkey Department of Neurology, Medical University of Vienna, Vienna, Austria Dr Gönül Bingöl-Dr Muammer Bingöl Çocuk ve Ergen Başağrısı Derneği – Society for Headache in Children and Adolescents, Suadiye, Istanbul, Turkey Department of Neuromedicine and Movement Science, Norwegian University of Science and Technology, Edvard Griegs gate, Trondheim, Norway Division of Brain Sciences, Imperial College London, London, UK AN - 149789457. Language: English. Entry Date: 20210419. Revision Date: 20210419. Publication Type: Article AU - Genc, Diana AU - Vaičienė-Magistris, Nerija AU - Zaborskis, Apolinaras AU - Şaşmaz, Tayyar AU - Tunç, Aylin Yeniocak AU - Uluduz, Derya AU - Wöber, Christian AU - Wöber-Bingöl, Çiçek AU - Steiner, Timothy J. DB - cin20 DO - 10.1186/s10194-021-01237-3 DP - EBSCOhost IS - 1 KW - Headache -- Epidemiology -- Lithuania Child Health Adolescent Health School Health Human Lithuania Child Adolescence Cross Sectional Studies Structured Questionnaires Descriptive Statistics Migraine Headache Quality of Life Headache -- Symptoms Absenteeism Headache -- Chemically Induced N1 - research; tables/charts. Journal Subset: Biomedical; Continental Europe; Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. NLM UID: 100940562. PY - 2021 SN - 1129-2369 SP - 1-9 ST - The burden attributable to headache disorders in children and adolescents in Lithuania: estimates from a national schools-based study T2 - Journal of Headache & Pain TI - The burden attributable to headache disorders in children and adolescents in Lithuania: estimates from a national schools-based study UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=149789457&site=ehost-live&scope=site VL - 22 ID - 141 ER - TY - JOUR AB - Purpose Of Review: Headache is a common complaint among children and adolescents. School functioning is one of the most important life domains impacted by chronic pain in children. This review discusses the epidemiological and pathophysiological connections between headaches and school functioning including a suggested clinical approach.Recent Findings: The connection between recurrent and chronic headache and learning disabilities might be psychosocial (fear of failure) or anatomical (malfunctioning of the frontal and prefrontal areas). Only few population-based and clinical studies were done and good studies are still needed in order to understand the complex relationship better. However, relating to our patients' learning and school performance, history is crucial when a child with primary headaches is evaluated. Learning disabilities seem to have a high prevalence among children with primary headache syndromes especially migraine. The connection between the two is complex and might be either part of a common brain pathophysiology and/or a consequence of poor quality of life. AD - Pediatric Neurology Unit, Bnai Zion Medical Center, Bruce and Ruth Rappaport Faculty of Medicine , Technion , Haifa Israel Department of Pediatrics and Child Neuropsychiatry , University 'La Sapienza' , Rome Italy Glia Institute , Ribeirão Preto Brazil Glia Institute, Ribeirão Preto, SP, Brazil AN - 124070196. Language: English. Entry Date: 20180725. Revision Date: 20190619. Publication Type: journal article AU - Genizi, J. AU - Guidetti, V. AU - Arruda, M. AU - Arruda, M. A. DB - cin20 DO - 10.1007/s11916-017-0633-9 DP - EBSCOhost IS - 7 KW - Headache -- Physiopathology Educational Status Prevalence Child Learning Frontal Lobe -- Physiopathology Headache -- Psychosocial Factors Quality of Life Adolescence Headache -- Epidemiology Learning Disorders -- Etiology Migraine -- Physiopathology N1 - review; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 100970666. PMID: NLM28551735. PY - 2017 SN - 1531-3433 SP - 1-5 ST - Primary Headaches and School Performance-Is There a Connection? T2 - Current Pain & Headache Reports TI - Primary Headaches and School Performance-Is There a Connection? UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=124070196&site=ehost-live&scope=site VL - 21 ID - 358 ER - TY - JOUR AB - Several meta-analyses have demonstrated that the combination of electrical muscle activity and Temperature Biofeedback could be regarded as gold standard in chronic pediatric headaches. However, these techniques seem to be uneconomical and furthermore they are not directed to improve the social competence as well as resolve possible impairments in daily activities of the child. Therefore, multi-modal behavioral techniques have been proposed, but no studies comparing these with the gold standard were conducted. The present study compared the impact of a new multi-modal behavioral education and training program-MIPAS-Family-with a combined Biofeedback treatment, evaluating clinical efficacy as well as the effect on the quality of life (QoL) of children with chronic headaches. Thirty-four children and adolescents with recurrent headache, ranging from 7 to 16 years, were randomly assigned to the MIPAS-Family ( N = 19) or the Biofeedback ( N = 15) condition. All patients were diagnosed by the criteria of the International Headache Society. The children and their parents completed headache diaries, diaries of daily living activities and a QoL questionnaire (KINDL(R)). Both groups showed significant improvements concerning the headache intensity and headache duration. We found no significant differences in the main headache parameters between both treatments. After the treatments, the children were less disturbed by their headaches in the domains school, homework, and leisure time. In conclusion, MIPAS-Family is as effective as Biofeedback but it is more cost-effective and addresses the whole family and the daily activities. AD - The Institute of Medical Psychology and Medical Sociology, University of Kiel, 24113 Kiel Germany AN - 105202960. Language: English. Entry Date: 20100702. Revision Date: 20150711. Publication Type: Journal Article AU - Gerber, W. AU - Petermann, F. AU - Gerber-von Müller, G. AU - Dollwet, M. AU - Darabaneanu, S. AU - Niederberger, U. AU - Schulte, I. E. AU - Stephani, U. AU - Andrasik, F. DB - cin20 DO - 10.1007/s10194-010-0192-5 DP - EBSCOhost IS - 3 KW - Biofeedback Headache -- In Infancy and Childhood Child Comparative Studies Descriptive Statistics Diaries Germany Human Inferential Statistics Patient Compliance Power Analysis Pretest-Posttest Design Program Evaluation Quality of Life Questionnaires Research Dropouts Sample Size Scales Statistical Significance Two-Way Analysis of Variance Visual Analog Scaling Wilcoxon Rank Sum Test N1 - research; tables/charts. Journal Subset: Biomedical; Continental Europe; Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. Instrumentation: KINDL Questionnaire; Pain Relevant Response Scale (PRRS) [adapted] [German]. NLM UID: 100940562. PMID: NLM20376520. PY - 2010 SN - 1129-2369 SP - 215-225 ST - MIPAS-Family---evaluation of a new multi-modal behavioral training program for pediatric headaches: clinical effects and the impact on quality of life T2 - Journal of Headache & Pain TI - MIPAS-Family---evaluation of a new multi-modal behavioral training program for pediatric headaches: clinical effects and the impact on quality of life UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105202960&site=ehost-live&scope=site VL - 11 ID - 627 ER - TY - JOUR AB - Background: Pediatric acupuncture within academic health centers is an expanding service, with more than one third of pediatric pain centers in the United States offering acupuncture-related modalities. Despite consumer demand for acupuncture, there is little information in the literature regarding the 'how-to' of building these programs. Methods: This article summarizes two models of incorporating pediatric acupuncture in academic health centers and describes methods of application of pediatric acupuncture within an academic health environment. Results: A comparison of these models and a blueprint for the development and success of acupuncture services within pediatric health centers are presented. Conclusions: Pediatric acupuncture can be a vital addition to holistic integrative care for children in an academic center, but requires collaborative implementation, particularly in the areas of clinical service, education, research, and reimbursement strategies. Long-term viability of pediatric acupuncture within an academic pediatric setting is aided by joint administrative support from the hospital and medical school, as well as measures of performance outcome and patient satisfaction. AN - 112814036. Language: English. Entry Date: 20160208. Revision Date: 20170515. Publication Type: Article AU - Gershan, Lynn A. DB - cin20 DO - 10.1089/act.2015.29039.lag DP - EBSCOhost IS - 1 KW - Acupuncture -- In Infancy and Childhood Integrative Medicine -- In Infancy and Childhood Child Acupuncture Points Child, Preschool Adolescence Academic Medical Centers Models, Theoretical Utah Minnesota Hospitals, Pediatric Education, Medical Inpatients Health Education Hospital Programs Outpatients N1 - tables/charts. Journal Subset: Alternative/Complementary Therapies; Biomedical; Peer Reviewed; USA. Special Interest: Pediatric Care. NLM UID: 9500579. PY - 2016 SN - 1076-2809 SP - 14-18 ST - Acupuncture in Pediatric Academic Health Centers: A Blueprint for Integration T2 - Alternative & Complementary Therapies TI - Acupuncture in Pediatric Academic Health Centers: A Blueprint for Integration UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=112814036&site=ehost-live&scope=site VL - 22 ID - 424 ER - TY - JOUR AB - Chest pain is a relatively common cause of admission to the Emergency Department, being related in most of the cases to benign conditions with only a minority of the cases affected by heart disease. Limited data are available about the follow up of these patients in terms of risk of recurrence of symptoms, Emergency Department re-admissions, level of impairment, and school absenteeism. We identified 761 children who visited our ED with the chief complaint of chest pain, equal to 0.68% of all admissions. Twenty-four patients were excluded for a previous history of cardiac disease. Eight (1%) patients were determined to have chest pain of cardiac origin. Ninety-seven percent of patients were successfully contacted by telephone: 69% agreed to answer the questionnaire. Of these, 33% experienced recurrent chest pain, up to 41% was forced to be absent from school, about 20% was limited in its daily activities, and about 20% repeated a cardiologic evaluation.Conclusion: Chest pain is mainly due to benign causes and is a recurrent symptom in a high percentage of patients, associated with re-admission and school absenteeism.What is Known:• Chest pain is a relatively common cause of admission to the Emergency Department.• It is mainly due to benign causes and is among the most common reasons for referral to the pediatric cardiologist.What is New:• Chest pain is a recurrent symptom associated with re-admission and school absenteeism.• As a family history of cardiac disease or exertional symptoms are a well-known red flag for chest pain of cardiac origin, school absenteeism should be considered a red flag for symptoms related to psychological distress in patients with non-cardiac chest pain. AD - Cardiology Service, Institute for Maternal and Child Health - IRCCS "Burlo Garofolo", Trieste, Italy University of Trieste, Trieste, Italy Pediatric Emergency Department, Institute for Maternal and Child Health - IRCCS "Burlo Garofolo", Trieste, Italy AN - 141292040. Language: English. Entry Date: 20201120. Revision Date: 20210201. Publication Type: journal article. Journal Subset: Biomedical AU - Gesuete, Valentina AU - Fregolent, Davide AU - Contorno, Sarah AU - Tamaro, Gianluca AU - Barbi, Egidio AU - Cozzi, Giorgio DB - cin20 DO - 10.1007/s00431-019-03495-5 DP - EBSCOhost IS - 2 KW - Patient History Taking Chest Pain -- Epidemiology Emergency Service -- Statistics and Numerical Data Chest Pain -- Diagnosis Length of Stay Gastrointestinal Diseases -- Epidemiology Diagnosis, Differential Child, Preschool Prospective Studies Heart Diseases -- Epidemiology Italy Heart Diseases -- Diagnosis Severity of Illness Indices Gastrointestinal Diseases -- Diagnosis Male Child Adolescence Incidence Hospitalization -- Statistics and Numerical Data Retrospective Design Hospitals, Special Female N1 - Continental Europe; Europe. NLM UID: 7603873. PMID: NLM31728674. PY - 2020 SN - 0340-6199 SP - 303-308 ST - Follow-up study of patients admitted to the pediatric emergency department for chest pain T2 - European Journal of Pediatrics TI - Follow-up study of patients admitted to the pediatric emergency department for chest pain UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=141292040&site=ehost-live&scope=site VL - 179 ID - 196 ER - TY - JOUR AB - Objective: School anxiety is a prevalent and debilitating mental health problem among youth with chronic pain. Despite evidence that anxiety in the context of school is associated with significant school-related disability, no studies have examined specific aspects of school anxiety in a pediatric chronic pain population.Materials and Methods: Adolescents with chronic pain (n=30) and age-matched and sex-matched controls (n=30) and their parents completed questionnaires assessing school anxiety and functioning.Results: Adolescents with chronic pain reported significantly more cognitive, behavioral, and psychophysiological symptoms of school anxiety relative to healthy controls. Youth with pain also endorsed significantly greater school anxiety in situations involving negative social evaluation and peer aggression. Exploratory analyses indicated that adolescents with chronic pain reporting school refusal behaviors more strongly endorsed behavioral and psychophysiological school anxiety symptoms, and more symptoms in social-evaluative situations. Youth with pain reporting lower school functioning endorsed more cognitive school anxiety symptoms and anxiety in situations involving academic failure relative to those reporting higher functioning.Discussion: Present results offer a nuanced perspective into the underlying sources of school anxiety among adolescents with chronic pain. Our findings may inform future research efforts and targeted school functioning interventions. In particular, findings suggest that an individualized approach to the assessment of school anxiety which considers the unique sources of anxiety (eg, social vs. academic) may lay the groundwork for the refinement of school functioning interventions in pediatric chronic pain. AD - Department of Psychology, University of Cincinnati, Cincinnati, OH. Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH. Department of Psychology, University of Cincinnati AN - 136882503. Language: English. Entry Date: 20200418. Revision Date: 20210304. Publication Type: journal article AU - Gibler, Robert C. AU - Beckmann, Emily A. AU - Lynch-Jordan, Anne M. AU - Kashikar-Zuck, Susmita AU - Jastrowski Mano, Kristen E. AU - Mano, Kristen E. Jastrowski DB - cin20 DO - 10.1097/AJP.0000000000000720 DP - EBSCOhost IS - 7 KW - Social Behavior Schools Anxiety Disorders -- Psychosocial Factors Anxiety -- Psychosocial Factors Chronic Pain -- Psychosocial Factors Anxiety Disorders -- Complications Male Female Human Chronic Pain -- Complications Peer Group Child Anxiety -- Complications Adolescence Validation Studies Comparative Studies Evaluation Research Multicenter Studies Social Readjustment Rating Scale N1 - research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 8507389. PMID: NLM31021887. PY - 2019 SN - 0749-8047 SP - 625-632 ST - Characterizing Social and Academic Aspects of School Anxiety in Pediatric Chronic Pain T2 - Clinical Journal of Pain TI - Characterizing Social and Academic Aspects of School Anxiety in Pediatric Chronic Pain UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=136882503&site=ehost-live&scope=site VL - 35 ID - 228 ER - TY - JOUR AB - Background: A pilot study was undertaken to test the methodology as well as the comprehensibility, validity and reliability of two questionnaires to be used in a study to determine prevalence of low back pain in schoolchildren in Mallorca and their parents. Methods: Fifty students from a school in Palma de Mallorca, aged 13-15 years, were surveyed from September to December 1996, as well as their parents. The questionnaires were distributed to the students by the study's school coordinator. Evaluation of the questionnaires was done through the test-retest method, the test through a self-administered, written version and the retest through an interview. Questions were asked on presumed risk factors for low back pain and on topics associated with its characteristics. Results: The system designed for the data collection phase was successful. Difficulties with comprehension centred mainly around two questions: sports and alcohol intake. Validity was only assessed on two student questions (academic problems and ever/never diagnosis of scoliosis) and the validity measures used were concordance of students' and parents' responses and concordance of students' responses with the gold standard (academic and medical records). With respect to reliability there was a good test-retest correlation for each subject, except for students' hours of television watching, associated leg pain and problems with schoolwork (p=0.013, 0.043, and <0.001, respectively); and in parents' problems with schoolwork in their child (p 0.05).Conclusions: The female athletes may have altered force attenuation capability during RVSHs as identified by increased vGRF and force loading rate compared with the male athletes. Portable force plates may be potential tools to identify altered force attenuation in clinical settings. AD - Division of Occupational and Physical Therapy, The Sports Medicine Biodynamics Center, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 10001, Cincinnati, OH 45229-3039, USA Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 10001, Cincinnati, OH 45229-3039, USA. tim.hewett@cchmc.org. AN - 104570173. Language: English. Entry Date: 20120323. Revision Date: 20200708. Publication Type: journal article AU - Harrison, A. D. AU - Ford, K. R. AU - Myer, G. D. AU - Hewett, T. E. AU - Harrison, A. D. AU - Ford, K. R. AU - Myer, G. D. AU - Hewett, T. E. DB - cin20 DO - 10.1136/bjsm.2009.061788 DP - EBSCOhost IS - 3 KW - Leg -- Physiology Movement -- Physiology Reproduction Adolescence Basketball -- Physiology Biomechanics Cross Sectional Studies Female Male Soccer -- Physiology Sports Medicine -- Equipment and Supplies N1 - research. Journal Subset: Allied Health; Biomedical; Double Blind Peer Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. Grant Information: R03 AR057551-01A1/AR/NIAMS NIH HHS/United States. NLM UID: 0432520. PMID: NLM19858114. PY - 2011 SN - 0306-3674 SP - 198-202 ST - Sex differences in force attenuation: a clinical assessment of single-leg hop performance on a portable force plate T2 - British Journal of Sports Medicine TI - Sex differences in force attenuation: a clinical assessment of single-leg hop performance on a portable force plate UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104570173&site=ehost-live&scope=site VL - 45 ID - 590 ER - TY - JOUR AB - Objective: Parent responses can have a major impact on their child's pain. The purpose of this systematic review is to (a) identify and describe measures assessing pain-related cognitive, affective, and behavioral responses in parents of children with chronic pain and (b) meta-analyze reported correlations between parent constructs and child outcomes (i.e., pain intensity, functional disability, and school functioning). Prospero protocol registration ID: CRD42019125496.Methods: We conducted a systematic search of studies including a measure of parent/caregiver responses to their child's chronic pain. Study characteristics and correlations between parent measures and child outcomes were extracted. Data were summarized and meta-analyzed.Results: Seventy-nine met inclusion criteria using 18 different measures of cognitive/affective (n = 3), behavioral (n = 5), and multidimensional responses (n = 10). Measures were used a median of three times (range 1-48), predominantly completed by mothers (88%), and primarily in mixed pain samples. Psychometrics of measures were generally adequate. Meta-analyses were based on 42 papers across five measures. Results showed that each of the cognitive, affective, and behavioral parent constructs we examined was significantly associated with pain-related functional disability. A small number of measures assessing parent cognitions and affective functioning were associated with higher child pain intensity; however, the majority were not.Conclusion: Findings demonstrate that there is a wealth of measures available, with adequate reliability overall but a lack of psychometrics on temporal stability. Synthesizing data across studies revealed small effects between parent responses and child functioning, and even smaller and/or absent effects on child pain intensity. AD - Department of Anesthesiology, Perioperative, and Pain Medicine, Stanford University School of Medicine Department for Psychology, Centre for Pain Research, University of Bath AN - 142705537. Language: English. Entry Date: In Process. Revision Date: 20210401. Publication Type: journal article AU - Harrison, Lauren E. AU - Timmers, Inge AU - Heathcote, Lauren C. AU - Fisher, Emma AU - Tanna, Vivek AU - Bans, Tom Duarte Silva AU - Simons, Laura E. AU - Duarte Silva Bans, Tom DB - cin20 DO - 10.1093/jpepsy/jsaa005 DP - EBSCOhost IS - 3 KW - Pain Measurement -- Methods Parent-Child Relations Parents -- Psychosocial Factors Chronic Pain -- Psychosocial Factors Reproducibility of Results Mothers -- Psychosocial Factors Male Caregivers -- Psychosocial Factors Psychometrics Child Adolescence Human Female Meta Analysis Validation Studies Comparative Studies Evaluation Research Multicenter Studies Caregiver Strain Index Clinical Assessment Tools Impact of Events Scale Multidimensional Health Locus of Control Scales N1 - meta analysis; research. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Evidence-Based Practice. Instrumentation: Caregiver Strain Index; Functional Living Index: Cancer (FLIC) (Schipper et al); Impact of Events Scale (IES); Multidimensional Health Locus of Control Scale (MHLOC). NLM UID: 7801773. PMID: NLM32150254. PY - 2020 SN - 0146-8693 SP - 281-298 ST - Parent Responses to Their Child's Pain: Systematic Review and Meta-Analysis of Measures T2 - Journal of Pediatric Psychology TI - Parent Responses to Their Child's Pain: Systematic Review and Meta-Analysis of Measures UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=142705537&site=ehost-live&scope=site VL - 45 ID - 192 ER - TY - JOUR AB - Background and Purpose: Brachial plexus neuropraxia (BPN), or "burners" and "stingers", affect 50-65% of football players, with a high rate of recurrence and the potential, in rare cases, for catastrophic injury. Existing literature on rehabilitation of these athletes is limited. The purpose of this case report is to describe the successful and comprehensive rehabilitation of a subject with recurrent brachial plexus neuropraxia using range of motion exercises, cervical and periscapular strengthening, stabilization exercises, and activity modification. Case Description: The subject was a 17-year-old high school linebacker with repeated BPN episodes. He presented with limited cervical extension, rounded shoulder posture, and weakness of the cervical and periscapular stabilizers, and was known to tackle using the crown of his helmet. Physical therapy intervention consisted of regaining full passive & active range of motion and strength in the neck, shoulders and periscapular region, including several novel stretches and exercises to address the subject's unique presentation. Dynamic stabilization, postural control, safe tackling form, and long-term maintenance exercises were also addressed to decrease risk of injury recurrence. Outcomes: The subject regained full pain-free PROM, AROM, strength & stability throughout the upper body after ten treatment sessions over five weeks, and was able to return to full participation the next season with normal safe tackling form and no further episodes. Discussion: Despite the prevalence, chronic nature, and potentially devastating effects of BPN, little has been written regarding comprehensive rehabilitation of the condition. Regaining full upper body range of motion, strength, and dynamic stability, as well as normalizing tackling form, is essential to resolving BPN and preventing recurrence. AD - Praxis Physical Therapy & Human Performance, Vernon Hills, IL, USA AN - 134932267. Language: English. Entry Date: 20190301. Revision Date: 20191022. Publication Type: Article AU - Hartley, Ryan A. AU - Kordecki, Michael E. DB - cin20 DO - 10.26603/ijspt20181061 DP - EBSCOhost IS - 6 KW - Football Athletes, High School Chronic Disease -- Rehabilitation Brachial Plexus Neuropathies -- Rehabilitation Neck -- Pathology Lordosis -- Pathology Reinjury -- Prevention and Control Rehabilitation, Athletic -- Methods Physical Therapy Exercise Physiology Range of Motion Muscle Strengthening Joint Instability -- Prevention and Control Physical Activity Adolescence Balance, Postural Stretching Shoulder Pain -- Etiology Neck Pain -- Etiology Neck -- Radiography Teaching Materials Patient Education Upper Extremity -- Physiology Pain Measurement Male N1 - case study; consumer/patient teaching materials; pictorial; tables/charts. Journal Subset: Allied Health; USA. NLM UID: 101553140. PY - 2018 SN - 2159-2896 SP - 1061-1072 ST - REHABILITATION OF CHRONIC BRACHIAL PLEXUS NEUROPRAXIA AND LOSS OF CERVICAL EXTENSION IN A HIGH SCHOOL FOOTBALL PLAYER: A CASE REPORT T2 - International Journal of Sports Physical Therapy TI - REHABILITATION OF CHRONIC BRACHIAL PLEXUS NEUROPRAXIA AND LOSS OF CERVICAL EXTENSION IN A HIGH SCHOOL FOOTBALL PLAYER: A CASE REPORT UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=134932267&site=ehost-live&scope=site VL - 13 ID - 276 ER - TY - JOUR AB - The objective was to develop a brief questionnaire to assess short-term functioning decrements in adolescents with acute migraine. One hundred twenty-three potential items were generated by literature review and by interviewing adolescent migraineurs and migraine specialists. To reduce the items, 127 adolescents were asked to identify which items affected their daily functioning in the 24 hours following onset of a migraine, and to rate them on a 5-point scale from 'not very important' to 'extremely important.' Reduction to an 18-item questionnaire was performed by evaluating subject-perceived importance (number of times an item was chosen times mean importance score) in combination with principal components factor analysis. Five domains were identified: (1) activities, (2) social functioning, (3) cognitive functioning, (4) migraine headache symptoms, and (5) emotional functioning. Questions regarding school loss and school performance during a migraine were added to the final questionnaire as a separate outcome measure. The correlation between the rive domains as measured by the Spearman correlation coefficient ranged from 0.17 to 0.49 suggesting some, but minimal, overlap. Cronbach alpha for individual domains ranged from .50 to .84. The questionnaire was pilot-tested in 12 adolescent migraineurs to determine ease of administration and comprehension and revised to improve clarity. AD - Hartmaier and Associates, Austin, Texas AN - 107028912. Language: English. Entry Date: 20081219. Revision Date: 20200708. Publication Type: Journal Article AU - Hartmaier, S. L. AU - DeMuro-Mercon, C. AU - Linder, S. AU - Winner, P. AU - Santanello, N. C. DB - cin20 DO - 10.1046/j.1526-4610.2001.111006150.x DP - EBSCOhost IS - 2 KW - Migraine -- Psychosocial Factors -- In Adolescence Instrument Construction Functional Assessment -- In Adolescence Adolescence Female Male Questionnaires Research Instruments Spearman's Rank Correlation Coefficient Factor Analysis Descriptive Statistics Coefficient Alpha Summated Rating Scaling Self Report Human N1 - research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. Instrumentation: 24-hour Adolescent Migraine Questionnaire (24-hr AMQ). NLM UID: 2985091R. PMID: NLM11251699. PY - 2001 SN - 0017-8748 SP - 150-156 ST - Development of a brief 24-hour adolescent migraine functioning questionnaire T2 - Headache: The Journal of Head & Face Pain TI - Development of a brief 24-hour adolescent migraine functioning questionnaire UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=107028912&site=ehost-live&scope=site VL - 41 ID - 816 ER - TY - JOUR AB - Background: Recurrent pain is a common complaint among adolescents. Children learn to resolve or cope with pain largely through family dynamics, particularly maternal influences. By adolescence, young people possess an array of pain behaviors, the culmination of multiple opportunities for modeling and reinforcement of attitudes and beliefs about pain. Adolescence is a time of increased autonomy characterized by, among other complex factors, significant increases in peer influence. Although peers are influential in health-risk behavior, little is known how peers impact adolescents' pain experience. The present study explored the role of peers in adolescents' attitudes toward pain, pain behaviors and over-the- counter analgesics. Methods: Sixty-minute focus groups were conducted with a sample 24 junior high school students from Halifax, Nova Scotia, Canada (11 male: mean age = 13.45 years, range = 12-15 years; 13 female: mean age = 13.31 years, range = 12-15 years). Participants were randomly assigned to one of five same-gender focus groups designed to explore a wide breadth and depth of information. Sessions were run until theoretical data saturation. Textual data, from transcribed audiotapes, were analyzed with the constant comparative method. Results: Peer influences were apparent in how adolescents communicate about pain and how those communications effect pain expression. Overt pain responses to injury were primarily contextual and depended on perceived threats to peer-time and pain severity. Adolescents were intolerant of peers' pain behaviors when the cause was perceived as not severe. These attitudes impacted how adolescents responded to their own pain; males were careful not to express embarrassing pain in front of peers, females felt no restrictions on pain talk or pain expression. Evidence for peer influence on attitudes toward OTC analgesics was apparent in perceptions of over-use and ease of access. Findings are discussed within the context of social information-processing and gender role expectations. Conclusion: Little research has addressed how young people experience pain within the context of the psychosocial influences that dominate during adolescence. The findings provide some insight into the role of peer influences via verbal and non-verbal communication, in adolescents' pain experience. This exploratory study is a necessary first step in understanding the socialization of adolescents' pain experiences. AD - Interdisciplinary Research, IWK Health Centre, Halifax, Nova Scotia, B3K 6R8, Canada. jill.hatchette@iwk.nshealth.ca AN - 105219083. Language: English. Entry Date: 20100709. Revision Date: 20171129. Publication Type: Journal Article AU - Hatchette, J. E. AU - McGrath, P. J. AU - Murray, M. AU - Finley, G. A. DB - cin20 DP - EBSCOhost KW - Attitude to Health Pain -- Psychosocial Factors Peer Group Adolescence Adolescent Behavior Analgesics -- Therapeutic Use Child Communication Drugs, Non-Prescription -- Therapeutic Use Female Focus Groups Gender Identity Human Male Pain Measurement Pain -- Drug Therapy Qualitative Studies Sex Factors Socialization N1 - research. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 100967804. PMID: NLM18190716. PY - 2008 SN - 1471-2431 SP - 2-2 ST - The role of peer communication in the socialization of adolescents' pain experiences: a qualitative investigation T2 - BMC Pediatrics TI - The role of peer communication in the socialization of adolescents' pain experiences: a qualitative investigation UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105219083&site=ehost-live&scope=site VL - 8 ID - 694 ER - TY - JOUR AB - Background/Aims: Patients with sickle cell anemia can experience recurrent pain episodes, which affect quality of life. The reported prevalence of pain is higher in studies using patient diaries than in healthcare facility utilization data. Determining Effects of Platelet Inhibition on Vaso-Occlusive Events was a multinational study that assessed the efficacy and safety of prasugrel in reducing the rate of vaso-occlusive events in children with sickle cell anemia (NCT01794000) and included an electronic patient-reported outcome diary to record pain occurrence. We aimed to capture diary completion rates and compliance in children who used the electronic patient-reported outcome diary during the Determining Effects of Platelet Inhibition on Vaso-Occlusive Events study and examine factors contributing to diary completion rates and compliance. Methods: Daily electronic patient-reported outcome diary data were collected for up to 9 months in Determining Effects of Platelet Inhibition on Vaso-Occlusive Events participants aged 4 to <18 years in Africa, the Americas, Europe, and the Middle East. The questionnaires were available in 11 languages/dialects for collecting subjective (pain intensity, activity interference) and objective (study drug use, analgesic use, school attendance) data. Pain intensity was measured using the Faces Pain Scale-Revised. Data were entered by participants or caregivers and transferred wirelessly each day to a central database. Diary completion rates were the number of daily diary entries divided by the total number of expected daily diary entries. Percentages of participants who were compliant with the diary (=80% diary completion) were calculated. Results: A total of 311 participants received a diary; 268 provided diary data through Month 9. Diary completion rates and compliance were high throughout the collection period and across all groups and regions, despite no games being included on the device. For subjective data, the overall completion rate was 94.4%, and 92.6% of participants were compliant. For objective data, the overall completion rate was 93.3%, and 89.7% of participants were compliant. Completion rates and compliance differed significantly by age and region and were higher for 4 to <12 year olds and very much higher for participants from Africa and the Middle East. Caregivers almost always entered data for participants <6 years and rarely entered data for participants =12 years. Comparing participant-entered and caregiver-entered data, pain intensity score data were more consistent for 4 to <12 year olds than older children, but pain intensity scores for older children were higher when entered by caregivers. Conclusion: With appropriate design, participant training, and sufficient monitoring, an electronic patient-reported outcome diary can capture daily sickle cell-related pain data in large multinational studies. Providing a mechanism for caregiver reporting is particularly valuable for participants <6 years and may also facilitate compliance in older children who experience high levels of pain. AD - Eli Lilly and Company, Indianapolis, IN, USA Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA UCSF Benioff Children's Hospital Oakland, Oakland, CA, USA School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana Malaria Research Centre, Agogo Presbyterian Hospital, Agogo, Ghana Department of Medical Oncology & Hematology, Faculty of Medicine, Zagazig University, Zagazig, Egypt Department of Pediatrics, University of Milano-Bicocca, Monza, Italy Emory University School of Medicine and AFLAC Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, USA AN - 126603571. Language: English. Entry Date: 20171211. Revision Date: 20171211. Publication Type: Article AU - Heath, Lori E. AU - Heeney, Matthew M. AU - Hoppe, Carolyn C. AU - Adjei, Samuel AU - Agbenyega, Tsiri AU - Badr, Mohamed AU - Masera, Nicoletta AU - Chunmei, Zhou AU - Brown, Patricia B. AU - Jakubowski, Joseph A. AU - Dampier, Carlton DB - cin20 DO - 10.1177/1740774517723307 DP - EBSCOhost IS - 6 KW - Pediatrics Pain -- Diagnosis Diaries Anemia, Sickle Cell -- Physiopathology Child Clinical Trials Human Recurrence Quality of Life Prevalence Safety Platelet Aggregation Inhibitors -- Therapeutic Use Anemia, Sickle Cell -- Diagnosis Reports Outcomes (Health Care) Africa United States Europe Questionnaires Geographic Locations Pain -- Complications Wireless Communications Data Analysis Software Patient Compliance Caregivers Middle East Hematology N1 - clinical trial; research; tables/charts. Journal Subset: Biomedical; Europe; UK & Ireland. NLM UID: 101285473. PY - 2017 SN - 1740-7745 SP - 563-571 ST - Successful utilization of an electronic pain diary in a multinational phase 3 interventional study of pediatric sickle cell anemia T2 - Clinical Trials TI - Successful utilization of an electronic pain diary in a multinational phase 3 interventional study of pediatric sickle cell anemia UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=126603571&site=ehost-live&scope=site VL - 14 ID - 332 ER - TY - JOUR AB - Adult patients with chronic pain are consistently shown to interpret ambiguous health and bodily information in a pain-related and threatening way. This interpretation bias may play a role in the development and maintenance of pain and disability. However, no studies have yet investigated the role of interpretation bias in adolescent patients with pain, despite that pain often first becomes chronic in youth. We administered the Adolescent Interpretations of Bodily Threat (AIBT) task to adolescents with chronic pain (N = 66) and adolescents without chronic pain (N = 74). Adolescents were 10 to 18 years old and completed the study procedures either at the clinic (patient group) or at school (control group). We found that adolescents with chronic pain were less likely to endorse benign interpretations of ambiguous pain and bodily threat information than adolescents without chronic pain, particularly when reporting on the strength of belief in those interpretations being true. These differences between patients and controls were not evident for ambiguous social situations, and they could not be explained by differences in anxious or depressive symptoms. Furthermore, this interpretation pattern was associated with increased levels of disability among adolescent patients, even after controlling for severity of chronic pain and pain catastrophizing. The current findings extend our understanding of the role and nature of cognition in adolescent pain, and provide justification for using the AIBT task in longitudinal and training studies to further investigate causal associations between interpretation bias and chronic pain. AD - Department of Experimental Psychology, University of Oxford, Oxford, United Kingdom Department of Anesthesiology, Pain, and Perioperative Medicine, Stanford University, CA, USA Oxford Centre for Children and Young People in Pain (OxCYPP), Nuffield Orthopaedic Centre, Oxford, United Kingdom Centre for Pain Research, University of Bath, Bath, United Kingdom Department of Clinical and Health Psychology, Ghent University, Ghent, Belgium Department of Psychology, King's College London, London, United Kingdom Department of Psychology, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, 16 De Crespigny Park, London, SE58AF, United Kingdom AN - 122603368. Language: English. Entry Date: 20170614. Revision Date: 20170424. Publication Type: Article. Journal Subset: Biomedical AU - Heathcote, L. C. AU - Jacobs, K. AU - Eccleston, C. AU - Fox, E. AU - Lau, J. Y. F. DB - cin20 DO - 10.1097/j.pain.0000000000000781 DP - EBSCOhost IS - 3 N1 - Continental Europe; Europe; Peer Reviewed. NLM UID: 7508686. PMID: NLM28067692. PY - 2017 SN - 0304-3959 SP - 471-478 ST - Biased interpretations of ambiguous bodily threat information in adolescents with chronic pain T2 - PAIN TI - Biased interpretations of ambiguous bodily threat information in adolescents with chronic pain UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=122603368&site=ehost-live&scope=site VL - 158 ID - 371 ER - TY - JOUR AB - OBJECTIVES: To evaluate short and long-term treatment outcome of children (7-10 years) in comparison to adolescents (11-18 years) with disabling chronic pain following multimodal inpatient pain treatment. PATIENTS AND METHODS: Thirty-three children and 167 adolescents underwent multimodal inpatient pain treatment. Standardized assessment of pain-related variables, disability, coping, and use of analgesics was performed at admission, 3- and 12-month follow-up. RESULTS: Children and adolescents displayed similar pain-characteristics at admission. Adolescents demonstrated significantly higher disability and passive pain coping. Children relied more on others when in pain. All core variables (i.e., pain intensity, pain-related disability, school absence and pain-related coping) decreased significantly in both children and adolescents after 3 months. Both groups maintained this decline 12 months later. More than half of the children and adolescents demonstrated a 50%-reduction in pain intensity after 3 months, and almost 60% after 12 months. Use of analgesics was significantly reduced at 3-month follow-up with no additional changes after 12 months. While age did not exert any impact on results, there were significant gender differences in pain intensity and school absence. Girls demonstrated higher pain intensity and higher school absence 1 year following treatment. CONCLUSIONS: Children display similar pain-characteristics to adolescents when entering inpatient treatment. A multimodal inpatient program appears to stop the the long-term vicious cycle of disability and pain for both children and adolescents. The demonstrated gender differences raise issues for further research and the possibility of additional pain management strategies for girls. AD - Vodafone Foundation Institute for Children's Pain Therapy and Paediatric Palliative Care, Clinic for Children and Adolescents Datteln, University of Witten/Herdecke, Datteln, Germany. T.Hechler@kinderklinik-datteln.de AN - 105127586. Language: English. Entry Date: 20100507. Revision Date: 20200708. Publication Type: Journal Article AU - Hechler, T. AU - Blankenburg, M. AU - Dobe, M. AU - Kosfelder, J. AU - Hübner, B. AU - Zernikow, B. DB - cin20 DO - 10.1016/j.ejpain.2009.03.002 DP - EBSCOhost IS - 1 KW - Pain -- Therapy Adaptation, Psychological Adolescence Age Factors Analgesics -- Administration and Dosage Analgesics -- Therapeutic Use Child Chronic Disease Combined Modality Therapy Disability Evaluation Female Hospitalization Human Inpatients Male Pain -- Epidemiology Pain -- Psychosocial Factors Pain Clinics Pain Measurement Multidisciplinary Care Team Questionnaires Schools Sex Factors Treatment Outcomes N1 - research. Journal Subset: Biomedical; Blind Peer Reviewed; Continental Europe; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. NLM UID: 9801774. PMID: NLM19362031. PY - 2010 SN - 1090-3801 SP - 97.e1-9 ST - Effectiveness of a multimodal inpatient treatment for pediatric chronic pain: a comparison between children and adolescents T2 - European Journal of Pain TI - Effectiveness of a multimodal inpatient treatment for pediatric chronic pain: a comparison between children and adolescents UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105127586&site=ehost-live&scope=site VL - 14 ID - 638 ER - TY - JOUR AB - OBJECTIVE: The present study aimed to investigate the effectiveness of a 3-week multimodal inpatient pain program for children and adolescents with chronic pain. METHODS: Effectiveness was investigated for pain-related variables (pain intensity, pain-related disability) and emotional distress in 3 ways: (1) in terms of statistically significant changes; (2) in terms of the clinical significance of these changes by creating post-hoc outcome groups for pain-related variables and emotional distress; and (3) in terms of the clinically significant overall amelioration generalizing the outcome over 3 variables (ie, pain intensity, pain-related disability, and school absence). One hundred sixty-seven adolescents (aged between 11 and 18 y) with various pain disorders (50% with headache) who met inpatient criteria were evaluated at baseline and 3 months posttreatment. RESULTS: Patients demonstrated statistically significant changes in all variables with large to medium effect sizes. Seventy-two percent and 45% of the patients demonstrated clinically significant changes in pain intensity and pain-related disability, respectively. The percentages of patients demonstrating clinically significant change in emotional distress ranged from 13% to 26%. Seventy-seven adolescents demonstrated overall amelioration. DISCUSSION: Results of the study are promising in at least 2 ways: (1) a multimodal inpatient program might stop the negative effects of chronic pain, disability, and emotional distress in children and adolescents, and (2) the exploration of clinical significance testing has demonstrated utility and can be applied to future effectiveness studies in pediatric pain. AD - Vodafone Foundation Institute of Children's Pain Therapy and Palliative Care, Datteln, Germany. T.Hechler@kinderklinik-datteln.de AN - 105491760. Language: English. Entry Date: 20090717. Revision Date: 20150711. Publication Type: Journal Article AU - Hechler, T. AU - Dobe, M. AU - Kosfelder, J. AU - Damschen, U. AU - Hübner, B. AU - Blankenburg, M. AU - Sauer, C. AU - Zernikow, B. DB - cin20 DO - 10.1097/AJP.0b013e318185c1c9 DP - EBSCOhost IS - 2 KW - Pain -- Psychosocial Factors Pain -- Therapy Adolescence Adult Child Chronic Disease Combined Modality Therapy Emotions Female Male Pain -- Complications Prospective Studies Reproducibility of Results Severity of Illness Indices Treatment Outcomes Human N1 - research. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 8507389. PMID: NLM19333163. PY - 2009 SN - 0749-8047 SP - 156-166 ST - Effectiveness of a 3-week multimodal inpatient pain treatment for adolescents suffering from chronic pain: statistical and clinical significance T2 - Clinical Journal of Pain TI - Effectiveness of a 3-week multimodal inpatient pain treatment for adolescents suffering from chronic pain: statistical and clinical significance UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105491760&site=ehost-live&scope=site VL - 25 ID - 667 ER - TY - JOUR AB - BACKGROUND AND OBJECTIVE: Pediatric debilitating chronic pain is a severe health problem, often requiring complex interventions such as intensive interdisciplinary pain treatment (IIPT). Research is lacking regarding the effectiveness of IIPT for children. The objective was to systematically review studies evaluating the effects of IIPT. METHODS: Cochrane, Medline/Ovid, PsycInfo/OVID, PubMed, PubPsych, and Web of Science were searched. Studies were included if (1) treatment was coordinated by ≥3 health professionals, (2) treatment occurred within an inpatient/day hospital setting, (3) patients were <22 years, (4) patients experienced debilitating chronic pain, (5) the study was published in English, and (6) the study had ≥10 participants at posttreatment. The child's pain condition, characteristics of the IIPT, and 5 outcome domains (pain intensity, disability, school functioning, anxiety, depressive symptoms) were extracted at baseline, posttreatment, and follow-up. RESULTS: One randomized controlled trial and 9 nonrandomized treatment studies were identified and a meta-analysis was conducted separately on pain intensity, disability, and depressive symptoms revealing positive treatment effects. At posttreatment, there were large improvements for disability, and small to moderate improvements for pain intensity and depressive symptoms. The positive effects were maintained at short-term follow-up. Findings demonstrated extreme heterogeneity. CONCLUSIONS: Effects in nonrandomized treatment studies cannot be attributed to IIPT alone. Because of substantial heterogeneity in measures for school functioning and anxiety, meta-analyses could not be computed. There is preliminary evidence for positive treatment effects of IIPT, but the small number of studies and their methodological weaknesses suggest a need for more research on IIPTs for children. AD - German Paediatric Pain Centre, Children's Hospital Datteln, Department of Children's Pain Therapy and Paediatric Palliative Care, Faculty of Health-School of Medicine, Witten/Herdecke University, Witten, Germany Behavior Medicine Pain Treatment Services, Karolinska University Hospital, Stockholm, Sweden; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden Division of Psychology Institute on Development and Disability, Oregon Health and Science University, Portland, Oregon Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts German Paediatric Pain Centre, Children's Hospital Datteln, Department of Children's Pain Therapy and Paediatric Palliative Care, Faculty of Health-School of Medicine, Witten/Herdecke University, Witten, Germany; University of Applied Sciences Osnabrueck, Osnabrueck, Germany AN - 109832305. Language: English. Entry Date: 20150720. Revision Date: 20200708. Publication Type: Journal Article AU - Hechler, Tanja AU - Kanstrup, Marie AU - Lewandowski Holley, Amy AU - Simons, Laura E. AU - Wicksell, Rikard AU - Hirschfeld, Gerrit AU - Zernikow, Boris DB - cin20 DO - 10.1542/peds.2014-3319 DP - EBSCOhost IS - 1 KW - Analgesia Chronic Pain -- Therapy -- In Infancy and Childhood Multidisciplinary Care Team Human Systematic Review Cochrane Library Medline PubMed Psycinfo Meta Analysis Confidence Intervals Data Analysis Software Depression Anxiety Child Stress, Psychological N1 - meta analysis; research; systematic review; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Evidence-Based Practice; Pain and Pain Management; Pediatric Care. NLM UID: 0376422. PMID: NLM26101358. PY - 2015 SN - 0031-4005 SP - 115-127 ST - Systematic Review on Intensive Interdisciplinary Pain Treatment of Children With Chronic Pain T2 - Pediatrics TI - Systematic Review on Intensive Interdisciplinary Pain Treatment of Children With Chronic Pain UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=109832305&site=ehost-live&scope=site VL - 136 ID - 448 ER - TY - JOUR AB - Pediatric chronic pain, which can result in deleterious effects for the child, bears the risk of aggravation into adulthood. Intensive interdisciplinary pain treatment (IIPT) might be an effective treatment, given the advantage of consulting with multiple professionals on a daily basis. Evidence for the effectiveness of IIPT is scarce. We investigated the efficacy of an IIPT within a randomized controlled trial by comparing an intervention group (IG) (n=52) to a waiting-list control group (WCG) (n=52). We made assessments before treatment (PRE), immediately after treatment (POST), as well as at short-term (POST6MONTHS) and long-term (POST12MONTHS) follow-up. We determined a combined endpoint, improvement (pain intensity, disability, school absence), and investigated 3 additional outcome domains (anxiety, depression, catastrophizing). We also investigated changes in economic parameters (health care use, parental work absenteeism, subjective financial burden) and their relationship to the child's improvement. Results at POST showed that significantly more children in the IG than in the WCG were assigned to improvement (55% compared to 14%; Fisher P<.001; 95% confidence interval for incidence difference: 0.21% to 0.60%). Although immediate effects were achieved for disability, school absence, depression, and catastrophizing, pain intensity and anxiety did not change until short-term follow-up. More than 60% of the children in both groups were improved long-term. The parents reported significant reductions in all economic parameters. The results from the present study support the efficacy of the IIPT. Future research is warranted to investigate differences in treatment response and to understand the changes in economic parameters in nonimproved children. AD - German Paediatric Pain Centre, Children's and Adolescents' Hospital, Datteln, Department of Children's Pain Therapy and Paediatric Palliative Care, Witten/Herdecke University, Faculty of Health, School of Medicine, Witten, Germany. Institute of Medical Biometrics and Epidemiology, Witten/Herdecke University, Faculty of Health, School of Medicine, Witten, Germany. German Paediatric Pain Centre, Children's and Adolescents' Hospital, Datteln, Department of Children's Pain Therapy and Paediatric Palliative Care, Witten/Herdecke University, Faculty of Health, School of Medicine, Witten, Germany. Electronic address: B.Zernikow@kinderklinik-datteln.de. AN - 104001404. Language: English. Entry Date: 20140912. Revision Date: 20210115. Publication Type: journal article AU - Hechler, Tanja AU - Ruhe, Ann-Kristin AU - Schmidt, Pia AU - Hirsch, Jessica AU - Wager, Julia AU - Dobe, Michael AU - Krummenauer, Frank AU - Zernikow, Boris DB - cin20 DO - 10.1016/j.pain.2013.09.015 DP - EBSCOhost IS - 1 KW - Analgesia -- Economics Analgesia -- Methods Chronic Pain -- Economics Chronic Pain -- Psychosocial Factors Chronic Pain -- Therapy Adolescence Anxiety -- Psychosocial Factors Child Depression -- Psychosocial Factors Disability Evaluation Female Human Inpatients Male Pain Measurement Prospective Studies Treatment Outcomes N1 - research; randomized controlled trial. Journal Subset: Biomedical; Continental Europe; Europe; Peer Reviewed. NLM UID: 7508686. PMID: NLM24060708. PY - 2014 SN - 0304-3959 SP - 118-128 ST - Inpatient-based intensive interdisciplinary pain treatment for highly impaired children with severe chronic pain: randomized controlled trial of efficacy and economic effects T2 - PAIN TI - Inpatient-based intensive interdisciplinary pain treatment for highly impaired children with severe chronic pain: randomized controlled trial of efficacy and economic effects UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104001404&site=ehost-live&scope=site VL - 155 ID - 503 ER - TY - JOUR AB - Background: In children with chronic pain, interdisciplinary outpatient and intensive inpatient treatment has been shown to improve pain intensity and disability. However, there are few systematic comparisons of outcomes of the two treatments. The present naturalistic study aimed to compare the clinical presentation and achieved changes at return in three outcome domains (pain intensity, disability, school absence) between a) outpatients vs. inpatients and b) patients who declined intensive inpatient treatment and completed outpatient treatment instead (decliners) vs. those who completed inpatient treatment (completers).Methods: The study compared treatment outcomes between n = 992 outpatients vs. n = 320 inpatients (Analysis A) who were treated at a tertiary treatment centre and returned for a return visit within a one-year interval. In Analysis B, treatment outcomes were compared between n = 67 decliners vs. n = 309 completers of inpatient treatment. The three outcome domains were compared by calculating standardized change scores and clinically significant changes.Results: In analysis A, outpatients and inpatients reported comparably low levels of pain intensity (NRS 0-10; mean = 4, SD = 2.7) and disability (Paediatric Pain Disability Index (PPDI: 12-60; mean = 24; SD = 10) at the return visit. Compared to outpatients, more inpatients achieved clinically significant changes in pain intensity (52% vs. 45%) and disability (46% vs. 31%). There were also significantly greater changes in disability in the inpatient group (change score outpatients = 1.0; change score inpatients = 1.4; F(1,1138) = 12.6, p = .011). School absence was substantially reduced, with approximately 80% in each group attending school regularly. Analysis B showed that even though inpatient decliners achieved improvements in the outcome domains, they reported greater disability at the return visit (PPDI mean decliners = 27, SD = 9.9; PPDI mean completers = 24, SD = 10) because they had achieved fewer changes in disability (change score decliners = 0.9; change score completers = 1.4; F(1.334) = 5.7, p = .017). In addition, less decliners than completers achieved clinically significant changes in disability (25% vs. 47%).Conclusions: Inpatient and outpatient treatments are able to elicit substantial changes in pain intensity, disability and school absence. The results highlight the necessity of intensive inpatient pain treatment for highly affected children, as children who declined inpatient treatment and were treated as outpatients did less well. AN - 109681498. Language: English. Entry Date: 20150213. Revision Date: 20200708. Publication Type: journal article AU - Hechler, Tanja AU - Wager, Julia AU - Zernikow, Boris DB - cin20 DO - 10.1186/1471-2431-14-262 DP - EBSCOhost IS - 1 N1 - research. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Pediatric Care. NLM UID: 100967804. PMID: NLM25308551. PY - 2014 SN - 1471-2431 SP - 262-262 ST - Chronic pain treatment in children and adolescents: less is good, more is sometimes better T2 - BMC Pediatrics TI - Chronic pain treatment in children and adolescents: less is good, more is sometimes better UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=109681498&site=ehost-live&scope=site VL - 14 ID - 497 ER - TY - JOUR AB - Purpose To investigate the prevalence of depressive symptoms, pain (headaches and stomachaches), and analgesic consumption in addition to the association between depressive symptoms and analgesic consumption among adolescents. Design and methods This cross-sectional study was conducted in southern Sweden. The survey was distributed among students in grade 8 (aged 13–15 years, n = 878). Results The prevalence of depressive symptoms (Center for Epidemiological Studies Depression Scale ≥16) was 37% among girls and 13% among boys. The prevalence rate of analgesic consumption to ease headaches and/or stomachaches during the last several weeks was 57% among girls and 29% among boys. Depressive symptoms are significantly associated with analgesic consumption among adolescents even after controlling for pain. Conclusion The knowledge that there is a higher use of analgesics in adolescents with depressive symptoms implies that healthcare professionals should focus on complex psychosocial problems, not only physiological pain, in adolescents. Practice implications Over the counter analgesics are frequently used by adolescents. Head and stomachaches are common reasons for students to visit the school nurse and primary healthcare facility. School nurses and pediatric nurses have to be aware of the link between depressive symptoms and pain in addition to the higher use of analgesics in adolescents with depressive symptoms. It is important to reduce the cause of the pain in order to prevent depressive symptoms and also analgesic overuse. Highlights • Depressive symptoms and pain (headache and stomachache) are common among adolescents, especially among adolescent girls. • There is lack of research regarding relationship between use of analgesics and depressive symptoms. • Use of analgesics is more common among adolescents with depressive symptoms even after controlling for self-reported pain. AD - Clinical Health Promotion Centre, Medical Faculty, Lund University, Lund, Sweden AN - 135438285. Language: English. Entry Date: 20190325. Revision Date: 20190708. Publication Type: Article AU - Hena, Momota AU - Leung, Cherry AU - Clausson, Eva K. AU - Garmy, Pernilla DB - cin20 DO - 10.1016/j.pedn.2018.12.008 DP - EBSCOhost KW - Depression -- Symptoms Pain -- Drug Therapy Analgesics -- Therapeutic Use Depression -- Epidemiology Drug Utilization Human Sweden Adolescence Male Female Cross Sectional Studies Center for Epidemiological Studies Depression Scale Psychological Tests Adolescent Health Pediatric Nursing Nursing Role Headache -- Prevention and Control Pain Management Questionnaires Academic Performance Descriptive Statistics Univariate Statistics Multiple Logistic Regression Chi Square Test Data Analysis Software Socioeconomic Factors Sex Factors Bivariate Statistics Depression -- Complications Funding Source N1 - research; tables/charts. Journal Subset: Core Nursing; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. Instrumentation: Center for Epidemiologic Studies Depression Scale (CES-D); Health Behavior in School-aged Children (HBSC). Grant Information: This work was supported by grants from the Amalia and Marcus Wallenberg Foundation, the Gyllenstierna Krapperup Foundation, the Clas Groschinski Memorial Foundation, the Queen Silvia Jubilee Fund, the Swedish Society of Nursing, the Jerringfonden, and the Crafoord Foundation.. NLM UID: 8607529. PY - 2019 SN - 0882-5963 SP - e19-e23 ST - Association of Depressive Symptoms with Consumption of Analgesics among Adolescents T2 - Journal of Pediatric Nursing TI - Association of Depressive Symptoms with Consumption of Analgesics among Adolescents UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=135438285&site=ehost-live&scope=site VL - 45 ID - 259 ER - TY - JOUR AB - Background: The management of menstruation has come to the fore as a barrier to girls' education attainment in low income contexts. Interventions have been proposed and piloted, but the emerging nature of the field means limited evidence is available to understand their pathways of effect. Methods: This study describes and compares schoolgirls' experiences of menstruation in rural Uganda at the conclusion of a controlled trial of puberty education and sanitary pad provision to elucidate pathways of effect in the interventions. Semi-structured interviews were undertaken with schoolgirls who participated in the Menstruation and the Cycle of Poverty trial concurrent with the final set of quantitative surveys. A framework approach and cross-case analysis were employed to describe and compare the experiences of 27 menstruating girls across the four intervention conditions; education (n = 8), reusable sanitary pads (n = 8), education with reusable sanitary pads (n = 6), and control (n = 5). Results: Themes included: menstrual hygiene, soiling, irritation and infection, physical experience, knowledge of menstruation, psychological, social and cultural factors, and support from others. Those receiving reusable pads experienced improvements in comfort and reliability. This translated into reduced fears around garment soiling and related school absenteeism. Other menstrual hygiene challenges of washing, drying and privacy remained prominent. Puberty education improved girls' confidence to discuss menstruation and prompted additional support from teachers and peers. Conclusions: Findings have important implications for the development and evaluation of future interventions. Results suggest the provision of menstrual absorbents addresses one core barrier to menstrual health, but that interventions addressing broader needs such as privacy may improve effectiveness. Puberty education sessions should increase attention to body awareness and include strategies to address a wider range of practical menstrual challenges, including pain management. Interviews revealed possibilities for improving quantitative surveys in future research. Trial registration: Pan-African Clinical Trials Registry PACTR201503001044408 AD - Centre for Evidence-Based Intervention, University of Oxford, 32 Wellington Square, Oxford OX1 2ER, UK SOAS, University of London, London, UK Bentley University, Waltham, MA, USA Department of Social Policy and Social Work, University of Birmingham, Birmingham, UK AN - 123962484. Language: English. Entry Date: 20170711. Revision Date: 20170711. Publication Type: Article AU - Hennegan, Julie AU - Dolan, Catherine AU - Steinfield, Laurel AU - Montgomery, Paul DB - cin20 DO - 10.1186/s12978-017-0339-9 DP - EBSCOhost KW - Puberty Reproductive Health -- Education Menstruation Human Semi-Structured Interview Rural Population Uganda Female Thematic Analysis Funding Source Interviews Pain Management Hygiene N1 - research; tables/charts. Journal Subset: Biomedical; Europe; UK & Ireland. Special Interest: Pain and Pain Management; Women's Health. Grant Information: The study was funded by a DFID-ESRC (Economic and Social Research Council) Grant (ref: ES/I034145/1).. NLM UID: 101224380. PY - 2017 SN - 1742-4755 SP - 1-12 ST - A qualitative understanding of the effects of reusable sanitary pads and puberty education: implications for future research and practice T2 - Reproductive Health TI - A qualitative understanding of the effects of reusable sanitary pads and puberty education: implications for future research and practice UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=123962484&site=ehost-live&scope=site VL - 14 ID - 360 ER - TY - JOUR AB - Background Migraine is one of the most common health problems for children and adolescents. If not successfully treated, it can impact patients and families with significant disability due to loss of school, work, and social function. When headaches become frequent, it is essential to try to prevent the headaches. For children and adolescents, this is guided by extrapolation from adult studies, a limited number of small studies in children and adolescents and practitioner preference. The aim of the Childhood and Adolescent Migraine Prevention ( CHAMP) study is to determine the most effective preventive agent to use in children and adolescents. Methods CHAMP is a double-blinded, placebo-controlled, multicenter, comparative effectiveness study of amitriptyline and topiramate for the prevention of episodic and chronic migraine, designed to mirror real-world practice, sponsored by the US National Institute of Neurological Disorders and Stroke/ National Institutes of Health ( U01NS076788). The study will recruit 675 subjects between the ages of 8 and 17 years old, inclusive, who have migraine with or without aura or chronic migraine as defined by the International Classification of Headache Disorders, 2nd Edition, with at least 4 headaches in the 28 days prior to randomization. The subjects will be randomized in a 2:2:1 (amitriptyline: topiramate: placebo) ratio. Doses are weight based and will be slowly titrated over an 8-week period to a target dose of 1 mg/kg of amitriptyline and 2 mg/kg of topiramate. The primary outcome will be a 50% reduction in headache frequency between the 28-day baseline and the final 28 days of treatment (weeks 20-24). Conclusions The goal of the CHAMP study is to obtain level 1 evidence for the effectiveness of amitriptyline and topiramate in the prevention of migraine in children and adolescents. If this study proves to be positive, it will provide information to the practicing physician as how to best prevent migraine in children and adolescents and subsequently improve the disability and outcomes. AD - Department of Pediatrics, College of Medicine, University of Cincinnati; Division of Neurology, Cincinnati Children's Hospital Medical Center Department of Pediatrics, College of Medicine, University of Cincinnati; Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center Department of Biostatistics, Clinical Trials Statistical and Data Management Center, University of Iowa Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center AN - 104071642. Language: English. Entry Date: 20140207. Revision Date: 20200708. Publication Type: Journal Article AU - Hershey, Andrew D. AU - Powers, Scott W. AU - Coffey, Christopher S. AU - Eklund, Dixie D. AU - Chamberlin, Leigh Ann AU - Korbee, Leslie L. DB - cin20 DO - 10.1111/head.12105 DP - EBSCOhost IS - 5 KW - Migraine -- Prevention and Control -- In Infancy and Childhood Migraine -- Drug Therapy -- In Adolescence Amitriptyline -- Therapeutic Use -- In Infancy and Childhood Topiramate -- Therapeutic Use -- In Infancy and Childhood Human Funding Source Double-Blind Studies Comparative Studies Child Adolescence Drug Therapy -- Evaluation Randomized Controlled Trials Questionnaires Male Female United States Prospective Studies Research Subject Recruitment -- Evaluation Time Factors Stratified Random Sample Amitriptyline -- Administration and Dosage Topiramate -- Administration and Dosage Chi Square Test Outcome Assessment Kaplan-Meier Estimator Electrocardiography N1 - equations & formulas; research; tables/charts; randomized controlled trial. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Pain and Pain Management; Pediatric Care. Instrumentation: Pediatric Quality of Life Inventory (PEDSQL); Hospital Anxiety and Depression Scale (HADS); Functional Disability Inventory (FDI); Headache Impact Test; Pediatric Migraine Disability Assessment (PedMIDAS); Behavioral Rating Inventory & Executive Function; Clinical Depression Inventory; Columbia-Suicide Severity Rating Scale Children's Baseline and Children's Since Last Visit. Grant Information: US National Institute of Neurological Disorders and Stroke/National Institutes of Health (Grant U01NS376788). NLM UID: 2985091R. PY - 2013 SN - 0017-8748 SP - 799-816 ST - Childhood and Adolescent Migraine Prevention ( CHAMP) Study: A Double-Blinded, Placebo-Controlled, Comparative Effectiveness Study of Amitriptyline, Topiramate, and Placebo in the Prevention of Childhood and Adolescent Migraine T2 - Headache: The Journal of Head & Face Pain TI - Childhood and Adolescent Migraine Prevention ( CHAMP) Study: A Double-Blinded, Placebo-Controlled, Comparative Effectiveness Study of Amitriptyline, Topiramate, and Placebo in the Prevention of Childhood and Adolescent Migraine UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104071642&site=ehost-live&scope=site VL - 53 ID - 525 ER - TY - JOUR AB - Objective The Chinese educational system is highly competitive from the start of primary school with great emphasis on academic performance and intolerance of failure. This study aimed to explore the pressures on primary schoolchildren, and to determine the relationship between these pressures and psychosomatic symptoms: abdominal pain and headache. Design Cross-sectional survey using self-completion questionnaires. Setting/participants 9- to 12-year-olds in primary schools in urban and rural areas of Zhejiang Province, eastern China. Outcome measures Proportion of children with defined school-related stressors and frequency of psychosomatic illness. Results Completed questionnaires were obtained from 2191 children. All stressors were common in boys and girls and in urban and rural schools. Eighty-one per cent worry 'a lot' about exams, 63% are afraid of the punishment of teachers, 44% had been physically bullied at least sometimes, with boys more often victims of bullying, and 73% of children are physically punished by parents. Over one-third of children reported psychosomatic symptoms at least once per week, 37% headache and 36% abdominal pain. All individual stressors were highly significantly associated with psychosomatic symptoms. Children identified as highly stressed (in the highest quartile of the stress score) were four times as likely to have psychosomatic symptoms. Conclusions The competitive and punitive educational environment leads to high levels of stress and psychosomatic symptoms in Chinese primary schoolchildren. Measures to reduce unnecessary stress on children in schools should be introduced urgently. AD - UCL Centre for International Health and Development, 30 Guilford Street, London WC1N 1EH, UK; t.hesketh@ich.ucl.ac.uk. AN - 105128919. Language: English. Entry Date: 20100528. Revision Date: 20150711. Publication Type: Journal Article AU - Hesketh, T. AU - Zhen, Y. AU - Lu, L. AU - Dong, Z. X. AU - Jun, Y. X. AU - Xing, Z. W. DB - cin20 DO - 10.1136/adc.2009.171660 DP - EBSCOhost IS - 2 KW - Psychophysiologic Disorders -- Epidemiology Stress, Psychological -- Epidemiology Students -- Psychosocial Factors Abdominal Pain -- Epidemiology Child China Cross Sectional Studies Female Headache -- Epidemiology Human Male Prevalence Psychophysiologic Disorders -- Etiology Rural Health Schools Stress, Psychological -- Psychosocial Factors Urban Health N1 - research. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. NLM UID: 0372434. PMID: NLM20133328. PY - 2010 SN - 0003-9888 SP - 136-140 ST - Stress and psychosomatic symptoms in Chinese school children: cross-sectional survey T2 - Archives of Disease in Childhood TI - Stress and psychosomatic symptoms in Chinese school children: cross-sectional survey UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105128919&site=ehost-live&scope=site VL - 95 ID - 633 ER - TY - JOUR AB - Problem: Children have reported that pain and anxiety were the most difficult part of hospitalization, and under treatment of pain and anxiety can have short and long term effects on health outcomes. Most healthcare professionals recognize a link between emotional health and physical health, but this may be especially true for pediatric patients who may not be able to marshal adequate coping skills due to their developmental age. Providing age appropriate alternatives, such as distraction therapy, may result in less invasive treatments for pediatric patients. Distraction therapy is an effective non-pharmacological intervention that is often under-utilized in the acute care setting. Providing an additional distraction intervention could help ameliorate the negative effects of hospitalization, enabling pediatric patients to decrease pain and anxiety while increasing coping and joy. Purpose: The purpose of the project was to spread awareness and to increase the use of a new, innovative distraction intervention in the form of an IV pole wagon. The wagons were developed in 2015 and were being used in a small, but rapidly increasing, group of pediatric hospitals. Background: Unfortunately, drug therapy, which should be second line treatment, is often the first line treatment despite evidence that non-pharmacological therapeutic interventions are similarly effective for the management of mild to moderate pain and anxiety. Distraction interventions, such as music therapy, pet interactions, video games, etc., have been shown to be successful therapies for mild to moderate pain and anxiety in children, but are under-utilized, resulting in unnecessary invasive amelioration therapies. Project Implementation: The cardinal goal for this DNP project was writing a business plan to provide a model for other pediatric organizations to start and maintain a nonprofit program to supply IV pole wagons to children in medical need. Secondary objectives included supportive measures to augment the business plan including marketing initiatives to inform the public/healthcare workers of the project, grant writing for funding, information dissemination by presenting at a nursing conference, and providing the IV pole wagons to facilities and individual families. The purpose of these interventions were to provide a developmentally appropriate distraction to lessen the pain and distress that can be associated with hospitalization while increasing pediatric coping and joy. The pilot program, called the Whee Wagon Program, was developed through Western Carolina University's (WCU) School of Nursing, in Cullowhee, NC, in August 2015. The project goal was to influence other pediatric organizations and/or advocacy groups to develop similar, but unique, programs to distribute these wagons to as many pediatric facilities as possible. Outcome: This project resulted in a comprehensive business plan to provide pediatric organizations with a blueprint for the development of their own program to provide IV pole wagons to children in medical need. The business plan, written in standard business plan format, was distributed to 14 pediatric organizations for their use. It was also published on the Western Carolina University Whee Wagon website and a proprietary Whee Wagon website for public use. This author presented the Whee Wagon concept at a pediatric nursing conference, and applied for, and was awarded, a $1,000 grant to disseminate the Whee Wagons to children in medical need. Finally, since the beginning of this project in January 2016, 22 wagons have been distributed to facilities or families. AN - 124664841. Language: English. Entry Date: 20180427. Revision Date: 20180621. Publication Type: Article AU - Hester, Susan W. DB - cin20 DP - EBSCOhost KW - Business Pediatric Care Human N1 - research; doctoral dissertation. I10267478 PY - 2017 SN - 9781369835335 SP - 1-1 ST - Business Plan for a Non-Profit Pediatric IV Pole Wagon Distribution Program T2 - Business Plan for a Non-Profit Pediatric IV Pole Wagon Distribution Program TI - Business Plan for a Non-Profit Pediatric IV Pole Wagon Distribution Program UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=124664841&site=ehost-live&scope=site ID - 377 ER - TY - JOUR AB - Background: There is a paucity of pediatric data addressing the complex relationship between primary headaches and sleep disturbances. Our study objective was to explore headache-related factors that predict sleep disturbance and to compare sleep complaints with other forms of headache-related disability among youth with migraines.Methods: A prospective cohort study was conducted in patients 10-18 years old with migraine or probable migraine and without daily sleep complaints. The patients completed a 90-day internet-based headache diary. On headache days, patients rated headache intensity, answered Pediatric Migraine Disability Assessment-based questions modified for daily scoring, and reported sleep disturbances that resulted as a direct effect of proximate headaches.Results: Fifty-two patients generated 4680 diary entries, 984 patients (21%) involved headaches. Headache intensity (P = 0.009) and timing of headache onset (P < 0.001) were predictive of sleep disturbances. Three Pediatric Migraine Disability Assessment-based items were also associated with sleep disturbances: partial school-day absence (P = 0.04), recreational activities prevented (P < 0.001), and decreased functioning during recreational activities (P < 0.001). Sleep disturbances correlated positively and significantly with daily headache disability scores (rpb = 0.35; P < 0.01).Conclusion: We conclude that specific headache factors predict sleep disturbances among youth with primary headaches. AN - 109680233. Language: English. Entry Date: 20150923. Revision Date: 20151105. Publication Type: journal article. Journal Subset: Biomedical AU - Heyer, Geoffrey L. AU - Rose, Sean C. AU - Merison, Kelsey AU - Perkins, Sara Q. AU - Lee, Jo Ellen M. DB - cin20 DO - 10.1016/j.pediatrneurol.2014.07.001 DP - EBSCOhost IS - 4 N1 - USA. Special Interest: Pediatric Care. NLM UID: 8508183. PMID: NLM25152963. PY - 2014 SN - 0887-8994 SP - 489-493 ST - Specific headache factors predict sleep disturbances among youth with migraine T2 - Pediatric Neurology TI - Specific headache factors predict sleep disturbances among youth with migraine UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=109680233&site=ehost-live&scope=site VL - 51 ID - 473 ER - TY - JOUR AB - Studies indicate that musculoskeletal discomfort and back pain problems are evident not only in adults, but also in children. We believe that educating towards a balanced-posture, body-function and movement patterns, as well as their ergonomic implications, can minimize and even prevent these problems. Such an ergonomics awareness educational program has to start at childhood and should be an integral part of the curriculum in the schools. This article presents the educational program 'Ergonomics, Movement and Posture' (EMP), which is taught in elementary schools by Physical Education (PE) students of the Kibbutzim College of Education in Israel, as part of their practicum. Although there has been no formal evaluation of the effectiveness of the program, so far, participating children, their parents, the teachers and the principles have offered positive feedback. AD - Department of Physical Education and Movement, Kibbutzim College of Education, Tel Aviv, Israel; ephrat_hey@smkb.ac.il AN - 105582151. Language: English. Entry Date: 20090123. Revision Date: 20150819. Publication Type: Journal Article AU - Heyman, E. AU - Dekel, H. DB - cin20 DP - EBSCOhost IS - 2 KW - Ergonomics -- Education -- In Infancy and Childhood School Health Education Child Curriculum -- Evaluation Israel Posture Sitting N1 - pictorial. Journal Subset: Allied Health; Europe; Peer Reviewed; UK & Ireland. NLM UID: 9204382. PMID: NLM18957743. PY - 2008 SN - 1051-9815 SP - 253-257 ST - Ergonomics for children: an educational program for elementary school T2 - Work TI - Ergonomics for children: an educational program for elementary school UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105582151&site=ehost-live&scope=site VL - 31 ID - 675 ER - TY - JOUR AB - Studies indicate that musculoskeletal discomfort and back pain problems are evident not only in adults, but also in children [1,2]. We believe that educating towards a balanced-posture, body-function and movement patterns, as well as their ergonomic implications, can minimize and even prevent these problems. Such an ergonomics awareness educational program has to start at childhood and should be an integral part of the curriculum in the schools. This article presents the educational program 'Ergonomics, Movement & Posture' (EMP), which is taught in elementary schools by Physical Education (PE) students of the Kibbutzim College of Education in Israel, as part of their practicum. Although there has been no formal evaluation of the effectiveness of the program, so far, participating children, their parents, the teachers and the principles have offered positive feedback. AD - Department of Physical Education and Movement, Kibbutzim College of Education, Tel Aviv, Israel. AN - 105512094. Language: English. Entry Date: 20090522. Revision Date: 20200708. Publication Type: Journal Article AU - Heyman, E. AU - Dekel, H. DB - cin20 DO - 10.3233/WOR-2009-0824 DP - EBSCOhost IS - 3 KW - Ergonomics -- Education -- In Infancy and Childhood Posture -- In Infancy and Childhood Child Education, Special Israel Lifting -- Education Sitting -- Education N1 - pictorial. Journal Subset: Allied Health; Europe; Peer Reviewed; UK & Ireland. NLM UID: 9204382. PMID: NLM19369718. PY - 2009 SN - 1051-9815 SP - 261-265 ST - Ergonomics for children: an educational program for elementary school T2 - Work TI - Ergonomics for children: an educational program for elementary school UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105512094&site=ehost-live&scope=site VL - 32 ID - 666 ER - TY - JOUR AB - The article discusses the various methods to figure out whether the child is sick or pretending to be sick. The article reports different complaints parents recieve from their kids which include head aches, fever, and stomach ache in which proper symptoms will guide a parent to take an appropriate step. It is suggested that there are many reasons kids make excuses to avoid school including being bullied in school, stressful class, and locker-room intimidation. AN - 124264932. Language: English. Entry Date: 20170729. Revision Date: 20170729. Publication Type: Article AU - Hill, David L. DB - cin20 DP - EBSCOhost IS - 9 KW - Pediatricians Disease -- Diagnosis -- In Infancy and Childhood Headache Abdominal Pain Fever Cough Pain Measurement Child Pharyngitis N1 - anecdote; pictorial. Journal Subset: Consumer Health; USA. NLM UID: 9891378. PY - 2017 SN - 1083-6373 SP - 34-39 ST - IS YOUR CHILD SICK OR JUST FAKING IT? T2 - Parents TI - IS YOUR CHILD SICK OR JUST FAKING IT? UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=124264932&site=ehost-live&scope=site VL - 92 ID - 353 ER - TY - JOUR AB - OBJECTIVE: The purpose was to compare orofacial (temporomandibular) pain with other pain complaints regarding impairment and health care utilization in a sample of 1,011 children and adolescents from a metropolitan area in Germany. METHOD AND MATERIALS: Individuals aged 10 to 18 years were sampled in schools using a 2-stage cluster technique. Orofacial pain in the previous month was assessed according to the Research Diagnostic Criteria for Temporomandibular Disorders. Additionally, participants were questioned about headache, back pain, abdominal pain, pain-related impairment, and health care utilization (visits to doctors, analgesic consumption) in the previous month. RESULTS: Headache was reported by 50% (95% CI: 45% to 56%) of participants, stomach pain by 36% (95% CI: 32% to 41%), back pain by 31% (95% CI: 25% to 36%), and orofacial pain by 15% (95% CI: 12% to 18%). Girls were more affected than boys. The range of 'severe' and 'very severe' impairment lay between 8% (orofacial pain) and 22% (headache). The range of treatment demand was between 10% and 17% (orofacial pain: 15%), and the range for analgesic consumption between 18% and 24% (orofacial pain: 22%). The more pain experienced, the more impairment, doctor consultations, and analgesic consumption were reported (Chi2test: P < 0.05). Risk of orofacial pain was 60% higher for subjects with head, back, and/or abdominal pain (odds ratio: 1.6; 95% CI: 1.3 to 1.9). CONCLUSION: In children and adolescents, orofacial pain occurs about half as often as other pain complaints. However, relative to their prevalence the different pain complaints are similar regarding impairment and health care utilization. AD - Clinic for Pediatric Dentistry, Dental School, Martin Luther University Halle Wittelberg, Halle, Germany; christian.hirsch@medizin.uni-halle.de AN - 106232976. Language: English. Entry Date: 20070209. Revision Date: 20150711. Publication Type: Journal Article AU - Hirsch, C. AU - John, M. T. AU - Schaller, H. AU - Türp, J. C. DB - cin20 DP - EBSCOhost IS - 5 KW - Abdominal Pain -- Epidemiology Back Pain -- Epidemiology Facial Pain -- Epidemiology Headache -- Epidemiology Health Services -- Utilization Adolescence Age Factors Analgesics -- Therapeutic Use Chi Square Test Child Cluster Sample Comparative Studies Confidence Intervals Data Analysis Software Descriptive Statistics Epidemiological Research Female Funding Source Germany Health Services Needs and Demand Interviews Intraclass Correlation Coefficient Logistic Regression Male Prevalence Questionnaires Reproducibility of Results Sample Size Sex Factors Temporomandibular Joint Diseases -- Epidemiology Urban Health Human N1 - research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Grant Information: Supported in part by the Ministry of Education of Saxony-Anhalt (#3292A/0080G) and by The German Academy of Natural Scientists Leopoldina (#BMBF-LPF 9901/8-4). NLM UID: 0342677. PMID: NLM16683686. PY - 2006 SN - 0033-6572 SP - 381-390 ST - Pain-related impairment and health care utilization in children and adolescents: a comparison of orofacial pain with abdominal pain, back pain, and headache T2 - Quintessence International TI - Pain-related impairment and health care utilization in children and adolescents: a comparison of orofacial pain with abdominal pain, back pain, and headache UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106232976&site=ehost-live&scope=site VL - 37 ID - 730 ER - TY - JOUR AB - Background: Migraine is a disabling, chronic neurological disease leading to severe headache episodes affecting 13.2% of the Swedish population. Migraine leads to an extensive socio-economic burden in terms of healthcare costs, reduced workforce and quality of life (QoL) but studies of the health-economic consequences in a Swedish context are lacking. The objective of this study is to map the health-economic consequences of migraine in a defined patient population in terms of healthcare consumption, production loss and QoL in Sweden. Methods: The study is based on data from a web-based survey to members in the Swedish patients' association suffering from migraine. The survey was conducted in May 2018 and included people with migraine aged 18 years or older. The survey included questions on health resource consumption, lost production resulting from migraine-related absenteeism and presenteeism, and QoL as measured by the EuroQol 5 dimensions questionnaire (EQ-5D-5 L) and the Headache Impact Test (HIT-6). The results are presented in yearly costs per patient and losses in quality adjusted life years (QALYs). Results: The results are based on answers from 630 individuals with migraine and are presented by number of migraine days per month. The total cost per patient and year increased with the number of migraine days per month (p < 0.001) and varied between approximately €5000 for those with less than 3 migraine days per month and €24,000 per year for those with 21–28 migraine days per month. Production loss represented the main part of the costs, approximately 80%. The average loss in QALYs per year also increased with the monthly number of migraine days (p = 0.023). Conclusions: Migraine leads to significant societal costs and loss of quality of life. There appears to be an unmet need and a potential for both cost savings and QoL benefits connected with a reduction in the number of migraine days. AD - The Swedish Institute for Health Economics (IHE), Lund, Sweden Department of Neuromedicine and Movement Sciences, NTNU Norwegian University of Science and Technology, Trondheim, Norway Tjörn Headache Clinic, Tjörn, Rönnäng, Sweden AN - 136747030. Language: English. Entry Date: 20190604. Revision Date: 20190604. Publication Type: Article AU - Hjalte, Frida AU - Olofsson, Sara AU - Persson, Ulf AU - Linde, Mattias DB - cin20 DO - 10.1186/s10194-019-1015-y DP - EBSCOhost IS - 1 KW - Migraine -- Economics -- Sweden Health Care Costs Economic Aspects of Illness Health Resource Utilization Quality-Adjusted Life Years Productivity Quality of Life Human Surveys Sweden Adolescence Adult Middle Age Aged Aged, 80 and Over Descriptive Statistics Cost Savings Questionnaires N1 - research; tables/charts. Journal Subset: Biomedical; Continental Europe; Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. Instrumentation: Headache Impact Test (HIT-6); EuroQol 5 dimensions questionnaire (EQ-5D-5 L). NLM UID: 100940562. PY - 2019 SN - 1129-2369 SP - N.PAG-N.PAG ST - Burden and costs of migraine in a Swedish defined patient population – a questionnaire-based study T2 - Journal of Headache & Pain TI - Burden and costs of migraine in a Swedish defined patient population – a questionnaire-based study UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=136747030&site=ehost-live&scope=site VL - 20 ID - 239 ER - TY - JOUR AB - Background: The proportion of Scandinavian school children reporting psychosomatic pain and psychological complaints have increased in recent decades. In this study we investigated these symptoms in relation to potential stressors in the school environment. Methods: A cross-sectional study was conducted based on child interviews linked to nationally representative household surveys in Sweden during 2002–2003 covering a sample of 2588 children aged 10–18 years. The main outcome variable of psychosomatic pain signified suffering from headache as well as recurrent abdominal pain on a weekly basis. Results: School stressors, such as harassment by peers, schoolwork pressure and being treated poorly by teachers, were associated with psychosomatic pain as well as psychological complaints such as sadness, irritability, feeling unsafe and nervous. Harassment was identified as a particularly important determinant with adjusted odds ratios (ORs) ranging from 3.1 to 8.6 for psychosomatic pain. All psychological complaints were associated with psychosomatic pain with adjusted ORs ranging from 2.2 to 3.7, and mediated most of the association of harassment to psychosomatic pain. Conclusions: School stressors are strongly associated with psychosomatic pain and psychological complaints in school children. Psychological complaints seem to function as mediators in the association of school stressors to psychosomatic pain symptoms to a great extent. AD - Department of Children's and Women's Health, Uppsala University, Uppsala, and Centre for Epidemiology, National Board of Health and Welfare, Stockholm, Sweden. AN - 105912084. Language: English. Entry Date: 20080509. Revision Date: 20171129. Publication Type: Journal Article AU - Hjern, A. AU - Alfven, G. AU - Ostberg, V. DB - cin20 DP - EBSCOhost IS - 1 KW - Adaptation, Psychological Pain -- Psychosocial Factors Psychology, Educational Psychophysiologic Disorders -- Epidemiology Stress, Psychological -- Epidemiology Adolescence Child Cross Sectional Studies Female Interviews Male Surveys Sweden Human N1 - research. Journal Subset: Biomedical; Continental Europe; Europe; Peer Reviewed. NLM UID: 9205968. PMID: NLM18076714. PY - 2008 SN - 0803-5253 SP - 112-117 ST - School stressors, psychological complaints and psychosomatic pain T2 - Acta Paediatrica TI - School stressors, psychological complaints and psychosomatic pain UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105912084&site=ehost-live&scope=site VL - 97 ID - 692 ER - TY - JOUR AB - Introduction: A continuing increase in prevalence of non-specific back pain in children and adolescents has been observed. The paper presents the results of a literature review on prevalence of back pain, the factors associated with the occurrence of back pain including gender, age, anthropometric parameters, lifestyle risk factors, school-related risk factors, the role of psychological, social, and behavioural factors and the efficacy of prevention in the treatment of nonspecific back pain in youth with no identified specific structural reason or cause. Methods: The electronic search of the following academic databases was conducted: Medline, PubMed, Google Scholar, PEDro, Springer Link, Elseviewer and The Cochrane Library. Included in the analysis were the cross-sectional, longitudinal, prospective and correlational research studies published between 2001 and 2011 in the English, German and Slovenian languages discussing nonspecific chronic or acute backpain and/or low back pain in children and adolescents. Only 50 out of 97 hits were analysed in the study. Results: Results of the study indicate that the occurrence of back pain has been increasing. According to the results, the observed prevalence increase of non-specific back pain may be related to female gender, age, school furniture, physical inactivity, high intensity training, traumas, previous history of back pain, rapid body growth, mechanical load (principally schoolbag carriage), decreased flexibility of the anterior and posterior thigh muscles, conduct and emotional problems and loneliness. Discussion and conclusion: Numerous etiological studies have identified the factors associated with the occurrence of back pain. The interventional prevention programmes have so far focused mainly on health education of children on proper posture and spine care education, pinpointing the importance of regular daily physical activity or a combination of both. AN - 107896707. Language: Slovak. Entry Date: 20140411. Revision Date: 20150712. Publication Type: Journal Article AU - Hlebs, Sonja AU - Gorjanc, Misa DB - cin20 DP - EBSCOhost IS - 2 KW - Back Pain -- Epidemiology -- In Adolescence Back Pain -- Epidemiology -- In Infancy and Childhood Back Pain -- Risk Factors -- In Adolescence Back Pain -- Risk Factors -- In Infancy and Childhood Acute Disease Adolescence Age Factors Back Pain -- Etiology Back Pain -- Prevention and Control Child Chronic Pain Cochrane Library Correlational Studies Cross Sectional Studies Female Human Male Medline Prevalence Prospective Studies PubMed Sex Factors Systematic Review N1 - research; systematic review. Journal Subset: Continental Europe; Europe; Nursing; Peer Reviewed. Special Interest: Evidence-Based Practice; Pain and Pain Management; Pediatric Care. NLM UID: 9518035. PY - 2013 SN - 1318-2951 SP - 184-193 ST - Risk factors for the development of back pain at young ages T2 - Obzornik Zdravstvene Nege TI - Risk factors for the development of back pain at young ages UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=107896707&site=ehost-live&scope=site VL - 47 ID - 521 ER - TY - JOUR AD - Department of Psychology, Simon Fraser University, 8888 University Drive, Burnaby, BC, Canada V5A 1S6. hyh@sfu.ca AN - 105479353. Language: English. Entry Date: 20090807. Revision Date: 20150711. Publication Type: Journal Article AU - Ho, G. H. AU - Bennett, S. M. AU - Cox, D. AU - Poole, G. DB - cin20 DO - jpepsy/jsn077 DP - EBSCOhost IS - 3 KW - Cognition Educational Status Intelligence Learning Pain -- Psychosocial Factors Psychomotor Performance Adolescence Child Chronic Disease Female Male Neuropsychological Tests Problem Solving Retrospective Design Schools Human N1 - research. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 7801773. PMID: NLM18653661. PY - 2009 SN - 0146-8693 SP - 311-316 ST - Brief report: cognitive functioning and academic achievement in children and adolescents with chronic pain T2 - Journal of Pediatric Psychology TI - Brief report: cognitive functioning and academic achievement in children and adolescents with chronic pain UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105479353&site=ehost-live&scope=site VL - 34 ID - 663 ER - TY - JOUR AB - On December 3, 2015, Public Health-Muskegon County (PHMC) in Michigan was notified by a local kindergarten-grade 2 school that a student aged 8 years (the index patient) had been sent home because of a rash suspected to be varicella (chickenpox); the rash had not been observed the previous day. Investigation by PHMC revealed that the student was one of five siblings in household A, none of whom had a history of having received any immunizations. During the preceding month the index patient's two older siblings (aged 12 years and 25 years) and two younger siblings (twins, aged 4 years) had been excluded from other schools in this rural district because of rashes that also were suspected to be varicella. Investigators also learned that a parent in household A had received a physician diagnosis of herpes zoster (shingles) nearly 7 weeks earlier, on October 20, after having been evaluated for a painful, unilateral trunk rash that had begun 3 days earlier, and for which acyclovir was prescribed. PHMC could not confirm whether any advice regarding prevention of possible transmission of varicella zoster virus to susceptible contacts was provided. The other children in household A had rash onsets on November 3, November 18 (two children), and November 22. The index patient rode a school bus and was the first student on and the last off each day; none of the index patient's four siblings attended the same school or rode on the same school bus as the index patient. Public health investigators subsequently linked three more cases in children to sharing the same school bus as the index patient. AN - 120354192. Corporate Author: Linda Scott. Language: English. Entry Date: 20170113. Revision Date: 20170113. Publication Type: journal article AU - Hoch, Douglas E. DB - cin20 DO - 10.15585/mmwr.mm6535a4 DP - EBSCOhost IS - 35 KW - Disease Outbreaks Motor Vehicles Chickenpox -- Epidemiology Herpes Zoster -- Epidemiology Child Chickenpox -- Diagnosis Chickenpox Vaccine -- Administration and Dosage Michigan Schools Child, Preschool Herpes Zoster -- Diagnosis Herpesviruses Exanthema Adult N1 - case study. Journal Subset: Biomedical; Public Health; USA. Instrumentation: Home Observation for Measurement of the Environment (HOME) (Bradley and Caldwell). NLM UID: 7802429. PMID: NLM27606936. PY - 2016 SN - 0149-2195 SP - 941-942 ST - Notes from the Field: Varicella Outbreak Associated with Riding on a School Bus - Muskegon County, Michigan, 2015 T2 - MMWR: Morbidity & Mortality Weekly Report TI - Notes from the Field: Varicella Outbreak Associated with Riding on a School Bus - Muskegon County, Michigan, 2015 UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=120354192&site=ehost-live&scope=site VL - 65 ID - 390 ER - TY - JOUR AB - Purpose: The purpose of this study was to examine Mexican American immigrant caregivers' beliefs and motivations surrounding the first dental visit for their young children (median age=5-years-old).Methods: Qualitative interviews were conducted among a convenience sample of 48 low-income, Mexican American mothers about their young children's oral health. Transcripts were independently read, coded, and thematically analyzed.Results: Half (51%) of first dental visits were for parent-initiated reasons, including: for pain or visible dental problems; for parent's proactive desire to get a checkup; or to avoid future dental problems. The other half was initiated by external prompts, especially pediatrician recommendations and school requirements. Once a child went to the dentist for his/her first visit, 94% continued with regular checkups. The mean age for a first dental visit was 3-years-old. Three parents reported cases in which dentists discouraged visits for symptomatic children before they were 3-years-old.Conclusions: The low-income, urban Mexican American parents interviewed take their children to their first dental visit when they are approximately 3-years-old, much later than the recommended 1-year-old first visit for this at-risk population. Physicians are well positioned to play an important role in prompting first dental visits. AD - Department of Preventive and Restorative Dental Sciences, History and Social Medicine, University of California, San Francisco, USA Research analyst, Department of Preventive and Restorative Dental Sciences and Department of Anthropology, History and Social Medicine. AN - 108204547. Language: English. Entry Date: 20120323. Revision Date: 20210325. Publication Type: journal article AU - Hoeft, K. S. AU - Barker, J. C. AU - Masterson, E. E. AU - Hoeft, Kristin S. AU - Barker, Judith C. AU - Masterson, Erin E. DB - cin20 DP - EBSCOhost IS - 5 KW - Dental Care for Children -- Psychosocial Factors Hispanic Americans -- Psychosocial Factors Mothers -- Psychosocial Factors California Child, Preschool Dental Caries -- Therapy Attitude to Health Health Services Accessibility Interviews Motivation Physician-Patient Relations Poverty Self Report Toothache -- Therapy N1 - research. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Dental Care; Pediatric Care. Grant Information: U54 DE14251/DE/NIDCR NIH HHS/United States. NLM UID: 7909102. PMID: NLM22104706. PY - 2011 SN - 0164-1263 SP - 392-398 ST - Maternal beliefs and motivations for first dental visit by low-income Mexican American children in California T2 - Pediatric Dentistry TI - Maternal beliefs and motivations for first dental visit by low-income Mexican American children in California UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=108204547&site=ehost-live&scope=site VL - 33 ID - 576 ER - TY - JOUR AB - Objectives: To study the efficacy of tailored behavioural medicine treatment within a physical therapy framework.Methods: The study was a randomized controlled study (RCT): tailored behavioural medicine treatment (EXT) delivered by physical therapists (PTs) was compared with exercise-based treatment (CT). Thirty-two adolescents (mean age 14.3 years) with persistent pain participated. Data on pain-related disability and school attendance (primary outcomes), pain intensity, catastrophizing, fear of movement and self-efficacy were collected.Results: The pain-related disability measured by the Functional Disability Inventory (FDI) resulted in mean score change of EXT = -18 and CT = -11, respectively. A significant change within both groups was found (EXT p = 0.003, CT p = 0.001), and a large effect size for FDI between the conditions was demonstrated (AUC of 0.77). For school attendance post-treatment, no difference was found between conditions. For secondary outcomes, a significant improvement in pain intensity and pain catastrophizing was found for the EXT and self-efficacy for the CT groups but no statistically significant difference between the two conditions was detected. Caution should be given to the small sample size, as it may affect the interpretation and generalizability of the results.Conclusion: In this study, differences between tailored behavioural medicine treatment delivered by PTs and exercise-based treatment could not be demonstrated, although the effect size was large. Patients who received either treatment demonstrated significant changes over time in pain-related disability. The low number of participants and suboptimal tailoring of the psychological components may partly explain the failure to demonstrate differences between groups, and future studies are warranted. AD - Department of Neuroscience, Uppsala University, Sweden Department of Women's and Children's Health, Uppsala University, Sweden Center of Health And Medical Psychology, School of Law, Psychology and Social Work, Örebro University, Sweden School of Health Care and Social Welfare, Mälardalen University, Västerås Sweden AN - 113707644. Language: English. Entry Date: 20161223. Revision Date: 20180629. Publication Type: journal article AU - Holm, S. AU - Ljungman, G. AU - Åsenlöf, P. AU - Linton, S. J. AU - Söderlund, A. DB - cin20 DO - 10.1002/ejp.780 DP - EBSCOhost IS - 4 KW - Behavioral Sciences Exercise Physical Therapy Primary Health Care Pain -- Therapy Pain -- Psychosocial Factors Male Fear Movement Self-Efficacy Human Age Factors Adolescence Female Validation Studies Comparative Studies Evaluation Research Multicenter Studies Randomized Controlled Trials Clinical Assessment Tools Scales N1 - research; randomized controlled trial. Journal Subset: Biomedical; Blind Peer Reviewed; Continental Europe; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. Special Interest: Evidence-Based Practice. Instrumentation: Functional Disability Inventory (FDI). NLM UID: 9801774. PMID: NLM26399225. PY - 2016 SN - 1090-3801 SP - 626-638 ST - Treating youth in pain: Comparing tailored behavioural medicine treatment provided by physical therapists in primary care with physical exercises T2 - European Journal of Pain TI - Treating youth in pain: Comparing tailored behavioural medicine treatment provided by physical therapists in primary care with physical exercises UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=113707644&site=ehost-live&scope=site VL - 20 ID - 414 ER - TY - JOUR AB - Background Attention-deficit/hyperactivity disorder (ADHD) in schoolchildren is often associated with troublesome relationships with family members and peers as well as difficulties in the classroom. The aims of this study were to assess the associations between attention-deficit/hyperactivity disorder (ADHD), recurrent subjective health complaints, and bullying in the peer group in schoolchildren. Method Cohort study of 577 fourth graders (10-year-olds) in 1 municipality in Stockholm County, Sweden. All children were screened for attention and behavior problems through interviews with their parents and teachers. Children with high scores underwent further clinical and cognitive assessments. Information about health complaints and bullying was collected from the children themselves in a classroom questionnaire. The 516 children for whom there was information from all 3 data sources were included in the final study population. Results Attention-deficit/hyperactivity disorder was associated with a 2-fold increased risk for recurrent abdominal pain (RAP), sleeping problems, and tiredness, while there was no association with headache. Bullying other students as well as being bullied were strongly associated with ADHD. There was a 2-fold increased risk for all kinds of health complaints among children being bullied, while bullies were more likely to report tiredness than other children. Conclusions Evaluation and treatment strategies for ADHD need to include an effective evaluation and treatment of RAP, tiredness, and sleeping disturbances as well as assessment and effective interventions for bullying. Evaluation of ADHD should be considered in children with recurrent health complaints and in children involved in bullying. Antibullying interventions are important to prevent health problems in all children. AN - 105105481. Language: English. Entry Date: 20101119. Revision Date: 20150711. Publication Type: Journal Article AU - Holmberg, K. DB - cin20 DO - 10.3810/pgm.2010.09.2202 DP - EBSCOhost IS - 5 KW - Aggression -- Psychosocial Factors Attention Deficit Hyperactivity Disorder -- Psychosocial Factors Social Dominance Abdominal Pain -- Epidemiology Abdominal Pain -- Psychosocial Factors Attention Deficit Hyperactivity Disorder -- Epidemiology Child Prospective Studies Fatigue -- Epidemiology Fatigue -- Psychosocial Factors Female Human Male Peer Group Recurrence Insomnia -- Epidemiology Insomnia -- Psychosocial Factors Sweden N1 - research. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 0401147. PMID: NLM20861589. PY - 2010 SN - 0032-5481 SP - 62-68 ST - The association of bullying and health complaints in children with attention-deficit/hyperactivity disorder T2 - Postgraduate Medicine TI - The association of bullying and health complaints in children with attention-deficit/hyperactivity disorder UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105105481&site=ehost-live&scope=site VL - 122 ID - 619 ER - TY - JOUR AB - Background: The association between socio-economic status (SES) and headache among adolescents is an understudied issue, and no study has examined whether such an association changes over time. The aim was to examine trends in socio-economic inequality in frequent headache among 11- to 15-year-olds in Denmark from 1991 to 2014, using occupational social class (OSC) as indicator of SES.Methods: The study applies data from the Danish part of the international Health Behaviour in School-aged Children (HBSC) study. HBSC includes nationally representative samples of 11-, 13- and 15-year-olds. This study combines data from seven data survey years from 1991 to 2014, participation rate 88.6%, n = 31,102. We report absolute inequality as per cent difference in frequent headache between high and low OSC and relative inequality as odds ratio for frequent headache by OSC.Results: In the entire study population, 10.4% reported frequent headache. There was a significant increase in frequent headache from 8.0% in 1991 to 12.9% in 2014, test for trend, p < 0.0001. This increasing trend was significant in all OSCs. The prevalence of frequent headache was significantly higher in low than high OSC, OR = 1.50 (95% CI: 1.34-1.67). This socio-economic inequality in frequent headache was persistent from 1991 to 2014.Conclusion: There was a significant and persistent socio-economic inequality, i.e. increasing prevalence of frequent headache with decreasing OSC. The association between socio-economic position and headache did not significantly change over time, i.e. the statistical interaction between OSC and survey year was insignificant.Significance: The prevalence of frequent headache among adolescents increases with decreasing SES. This socio-economic inequality has been persistent among adolescents in Denmark from 1991 to 2014. Clinicians should be aware of this social inequality. AD - National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark AN - 129077716. Language: English. Entry Date: 20190113. Revision Date: 20190501. Publication Type: journal article AU - Holstein, B. E. AU - Andersen, A. AU - Denbæk, A. M. AU - Johansen, A. AU - Michelsen, S. I. AU - Due, P. AU - Denbaek, A. M. DB - cin20 DO - 10.1002/ejp.1179 DP - EBSCOhost IS - 5 KW - Social Class Headache -- Epidemiology Socioeconomic Factors Human Prevalence Child Female Male Schools Adolescence Denmark Validation Studies Comparative Studies Evaluation Research Multicenter Studies N1 - research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Continental Europe; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. NLM UID: 9801774. PMID: NLM29349882. PY - 2018 SN - 1090-3801 SP - 935-940 ST - Short communication: Persistent socio-economic inequality in frequent headache among Danish adolescents from 1991 to 2014 T2 - European Journal of Pain TI - Short communication: Persistent socio-economic inequality in frequent headache among Danish adolescents from 1991 to 2014 UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=129077716&site=ehost-live&scope=site VL - 22 ID - 305 ER - TY - JOUR AB - A cross-sectional epidemiological study via personal interviews was performed regarding low back pain and its related clinical aspects in a Hungarian sample of 10,000 people. Joining the international campaign of the "Bone and Joint Decade", our aim was to give data on low back pain prevalence and to explore the underlying possible clinical conditions in a Central European adult and adolescent population. Ten thousand people aged 14-65, selected randomly by the Hungarian central office of statistics from three counties of the south-western Hungarian region, were surveyed using a special questionnaire focusing on low back pain and other degenerative spinal symptoms. People with low back pain complaints and written consent were asked to participate in a further clinical investigation, where radiological and clinical assessment was performed. A total of 4,389 persons (44.1%) reported low back pain in the last month at the time of the survey. Work absenteeism due to low back pain affected 2,140 persons (21.5%). A total of 292 people (2.9%) had already undergone spinal surgery. Upon request 682 people came for a clinical follow-up, where thorough physical examination and radiological analysis was performed and results were statistically interpreted. The Oswestry disability index (ODI) in the examined group of patients averaged 35.1%; radiological degenerative signs were observed in 392/682 (57.5%). Individuals with signs of radiological degeneration had a statistically significant higher ODI value, age, and a higher, yet not significantly increased BMI value than radiographically negative patients (p < 0.05). Co-existence of hip and knee osteoarthritis was also investigated. Higher osteoarthritis prevalence was found in individuals with radiographic signs of spinal degeneration. Details of the survey and clinical investigations are discussed. AD - Department of Orthopaedics, University of Pécs, Hungary Department of Orthopaedics, University of Pécs, Pécs, Hungary, honya75@hotmail.com. AN - 104942177. Language: English. Entry Date: 20110325. Revision Date: 20200708. Publication Type: journal article AU - Horváth, G. AU - Koroknai, G. AU - Acs, B. AU - Than, P. AU - Illés, T. AU - Horváth, Gábor AU - Koroknai, Gabriella AU - Acs, Barnabás AU - Than, Péter AU - Illés, Tamás DB - cin20 DO - 10.1007/s00264-009-0920-0 DP - EBSCOhost IS - 8 KW - Intervertebral Disk Displacement -- Epidemiology Low Back Pain -- Epidemiology Lumbar Vertebrae -- Pathology Adolescence Adult Aged Clinical Assessment Tools Comorbidity Cross Sectional Studies Disability Evaluation Female Human Hungary Intervertebral Disk Displacement -- Physiopathology Intervertebral Disk Displacement -- Radiography Low Back Pain -- Physiopathology Low Back Pain -- Radiography Lumbar Vertebrae -- Radiography Male Middle Age Osteoarthritis, Hip -- Epidemiology Osteoarthritis, Knee -- Epidemiology Prevalence Questionnaires Young Adult N1 - research. Journal Subset: Biomedical; Continental Europe; Europe; Peer Reviewed. Instrumentation: Oswestry Disability Index (ODI). NLM UID: 7705431. PMID: NLM19997731. PY - 2010 SN - 0341-2695 SP - 1245-1249 ST - Prevalence of low back pain and lumbar spine degenerative disorders. Questionnaire survey and clinical-radiological analysis of a representative Hungarian population T2 - International Orthopaedics TI - Prevalence of low back pain and lumbar spine degenerative disorders. Questionnaire survey and clinical-radiological analysis of a representative Hungarian population UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104942177&site=ehost-live&scope=site VL - 34 ID - 603 ER - TY - JOUR AB - Objectives: To determine, in preschool- and school-aged children with cerebral palsy (CP): (i) the prevalence of sleep disorders, including disorders of initiation and maintenance of sleep, and (ii) the association between child characteristics and sleep disorders.Methods: Children with CP aged 3-12 years were recruited from neurology clinics and a provincial CP registry. Caregivers completed the Sleep Disturbance Scale for Children (SDSC) and a questionnaire on sleep-related characteristics. Children's medical information was collected from the registry and hospital records.Results: 150 children with CP (mean age ± standard deviation: 6.9 ± 2.9 years) completed the study (66 preschool-and 84 school-aged children). An abnormal total score on the SDSC was found in 20.7% of children (10.6% and 28.6% of preschool-and school-aged children, respectively). Overall, 44.0% of children had one or more sleep disorder (24.2% and 59.5% in preschool-and school-aged children, respectively), as determined by subscales of the SDSC. The most common sleep problem, disorders of initiation and maintenance of sleep, was found in 26.0% of children (18.2% of preschool- and 32.1% of school-aged children, respectively). Pain was the strongest predictor of having an abnormal total score and disorders of initiation and maintenance of sleep, with odds ratios (95% confidence intervals) of 6.5 (2.2-18.9) and 3.4 (1.3-9.3), respectively, adjusted for age group and degree of motor impairment.Conclusions: Sleep disorders are prevalent in children with CP, with higher frequencies in school-aged as compared to preschool-aged children. Health care professionals caring for this population should routinely inquire about sleep problems and pain. AD - Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Montreal, Quebec, Canada Research Institute, McGill University Health Centre, Montréal, Québec, Canada Department of Neurology/Neurosurgery, Montreal Children's Hospital, McGill University Health Centre, Montreal, Quebec, Canada AN - 131789123. Language: English. Entry Date: In Process. Revision Date: 20191107. Publication Type: journal article AU - Horwood, Linda AU - Mok, Elise AU - Li, Patricia AU - Oskoui, Maryam AU - Shevell, Michael AU - Constantin, Evelyn DB - cin20 DO - 10.1016/j.sleep.2018.05.008 DP - EBSCOhost KW - Cerebral Palsy -- Complications Insomnia -- Epidemiology Pain -- Etiology Cerebral Palsy -- Classification Age Factors Child Male Female Cross Sectional Studies Canada Human Prevalence Validation Studies Comparative Studies Evaluation Research Multicenter Studies N1 - research. Journal Subset: Biomedical; Continental Europe; Europe. NLM UID: 100898759. PMID: NLM29966807. PY - 2018 SN - 1389-9457 SP - 1-6 ST - Prevalence of sleep problems and sleep-related characteristics in preschool- and school-aged children with cerebral palsy T2 - Sleep Medicine TI - Prevalence of sleep problems and sleep-related characteristics in preschool- and school-aged children with cerebral palsy UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=131789123&site=ehost-live&scope=site VL - 50 ID - 287 ER - TY - JOUR AB - Recurrent pain is a common childhood problem which for some becomes chronic and is associated with severely impaired functioning. Relationships of psychological variables with impaired functioning have rarely been investigated in samples of children reporting pain in non-clinical settings. The aim of this study was to examine the role of cognitive appraisal in the relationship between chronic pain and level of functioning in a normal school-attending population of children who report pain as a common experience. Five hundred and sixty one schoolchildren aged between 8 and 16 years and their parents participated in a cross-sectional interview and questionnaire study. Child functioning was measured in two ways: self-reported quality of life, and self-reported functional disability associated with pain. Results showed a consistent pattern across both specific measures of functioning used. Catastrophic appraisals of pain can explain partially the functional impairment found in a sample of normal schoolchildren with chronic pain. Positive expectations about ability, the responsibility to exert control over the pain, and the belief that medication and doctors will help to control the pain, were found to be protective of normal functioning in chronic pain. Cognitive factors were found to mediate but not moderate the relationship between pain and disability, and quality of life. AD - Dalhousie University, IWK Health Centre, 5850/5980 University Ave, Room K8508, PO Box 9700, Halifax, NS, B3K 6R8, Canada. anna.huguet@dal.ca AN - 105374873. Language: English. Entry Date: 20090925. Revision Date: 20150711. Publication Type: Journal Article AU - Huguet, A. AU - Eccleston, C. AU - Miró, J. AU - Gauntlett-Gilbert, J. DB - cin20 DO - 10.1016/j.ejpain.2008.07.011 DP - EBSCOhost IS - 7 KW - Cognition Pain -- Psychosocial Factors Adolescence Child Chronic Disease Cross Sectional Studies Data Analysis, Statistical Disability Evaluation Female Male Pain Measurement Parents -- Psychosocial Factors Prognosis Quality of Life Questionnaires Recurrence Regression Schools Socioeconomic Factors Spain Human N1 - research. Journal Subset: Biomedical; Blind Peer Reviewed; Continental Europe; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. NLM UID: 9801774. PMID: NLM18801680. PY - 2009 SN - 1090-3801 SP - 751-759 ST - Young people making sense of pain: cognitive appraisal, function, and pain in 8-16 year old children T2 - European Journal of Pain TI - Young people making sense of pain: cognitive appraisal, function, and pain in 8-16 year old children UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105374873&site=ehost-live&scope=site VL - 13 ID - 653 ER - TY - JOUR AB - This study was designed to (1) provide information on the prevalence of pediatric pain as well as other pain related characteristics in a sample of schoolchildren, and (2) study the suitability of a system to grade the severity of chronic pain problems among children. Participants in this cross-sectional study included 561 schoolchildren between the ages of 8 and 16 years. Besides collecting information about the presence of pain at the time of interview, and in the preceding 3 months, several characteristics of participants' pain experiences and several indicators of participants' quality of life were requested. Results showed that 37.3% had chronic pain, but only 5.1% had moderate or severe chronic pain problems. Gender and age differences were found in the prevalence of pain conditions. Children who had a chronic pain condition reported a worse quality of life, missed more days from school, and were more likely to use pain medication and seek medical care for pain relief. Our study shows that chronic pain is a highly prevalent condition in the community, one that can exert negative consequence for the child. But the prevalence of severe chronic pain cases is low. New studies are needed to further empirically test the proposed method of grading the severity of chronic pain in children. PERSPECTIVE: This article provides information on pain problems among schoolchildren. It also suggests a new grading system of chronic pediatric problems. This new system could help clinicians and researchers to diagnose pain problems in youth and design treatments suited to patients' characteristics and needs. AD - Department of Psychology, Rovira i Virgili University, Catalonia, Spain. AN - 105760489. Language: English. Entry Date: 20080711. Revision Date: 20200708. Publication Type: Journal Article AU - Huguet, A. AU - Miró, J. DB - cin20 DO - 10.1016/j.jpain.2007.10.015 DP - EBSCOhost IS - 3 KW - Chronic Pain -- In Infancy and Childhood Pain -- Epidemiology -- In Infancy and Childhood Severity of Illness -- In Infancy and Childhood Adolescence Age Factors Analysis of Variance Chi Square Test Child Clinical Assessment Tools Cross Sectional Studies Descriptive Statistics Epidemiological Research Female Interviews Male Pain -- Physiopathology Post Hoc Analysis Scales Schools, Elementary -- Spain Schools, Secondary -- Spain Sex Factors Socioeconomic Factors Spain Stratified Random Sample Summated Rating Scaling T-Tests Human N1 - research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. Instrumentation: Functional Disability Inventory (FDI); Pediatric Quality of Life Inventory Version 4.0 (PEDSQL); Faces Pain Scale--Revised (FPS-R). NLM UID: 100898657. PMID: NLM18088558. PY - 2008 SN - 1526-5900 SP - 226-236 ST - The severity of chronic pediatric pain: an epidemiological study T2 - Journal of Pain TI - The severity of chronic pediatric pain: an epidemiological study UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105760489&site=ehost-live&scope=site VL - 9 ID - 688 ER - TY - JOUR AB - Because children with physically unexplained chronic pain may become the adult chronic pain patients of the future and because little is known about this pain and its impact on children and their families, a sample of 77 children (aged 5-11 years) with this type of pain was investigated. The hypothesis was tested that a greater intensity and frequency of pain would diminish the child's functional status and increase the impact of pain on the family. All mothers completed questionnaires on their perception of the child's functional status and the impact of pain on the family, and kept a diary on the child's pain for three successive weeks, three times daily, by means of a visual analogue scale (VAS) and a behavioural list. The study was conducted in the general population in the Rotterdam area. Children with physically unexplained chronic pain were sampled from those participating in a prevalence study on chronic pain. The average pain was mild (30 mm on a 0-100 mm VAS), moderately frequent (34% of the diary registration time), increased during the day, and did not result in large school absence or problems with functional status. Pain showed a relatively negative impact on family life, especially restrictions in social life and personal strain were reported, based on behavioural changes. In particular, abdominal pain, headache and limb pain are already present in considerable numbers at a young age. Longitudinal research should determine whether shifts occur in pain experience and locations from childhood and adulthood and in different dimensions of functional status and, more broadly, in quality of life resulting from pain. AD - Dept of Medical Psychology and Psychotherapy, Erasmus University, PO Box 1738, 3000 DR Rotterdam, The Netherlands; hunfeld@mpp.fgg.eur.nl AN - 106589362. Language: English. Entry Date: 20050304. Revision Date: 20200708. Publication Type: Journal Article AU - Hunfeld, J. A. M. AU - Perquin, C. W. AU - Hazebroek-Kampschreur, A. A. J. AU - Passchier, J. AU - van Suijlekom-Smit, L. W. A. AU - van der Wouden, J. C. DB - cin20 DO - 10.1348/147608302320365172 DP - EBSCOhost IS - 3 KW - Chronic Pain -- Psychosocial Factors -- In Infancy and Childhood Mothers -- Psychosocial Factors Parental Attitudes -- Evaluation Chi Square Test Child Descriptive Statistics Diaries Female Health Status Indicators Kruskal-Wallis Test Linear Regression Male Multivariate Analysis of Variance Netherlands Pain Measurement Pearson's Correlation Coefficient Questionnaires Scales T-Tests Visual Analog Scaling Funding Source Human N1 - research; tables/charts. Journal Subset: Biomedical; Double Blind Peer Reviewed; Europe; Peer Reviewed; UK & Ireland. Instrumentation: Functional health Status Scale II-Revised version (FSII-R) (Stein and Jones Jessop); Impact on Family Scale (IFS) (Stein and Jones Jessop). Grant Information: Netherlands Organisation for Scientific Research Grant 940.31.038, and the Pain Knowledge Center, Erasmus University Medical Center, Rotterdam. NLM UID: 101135751. PY - 2002 SN - 1476-0835 SP - 251-260 ST - Physically unexplained chronic pain and its impact on children and their families: the mother's perception T2 - Psychology & Psychotherapy: Theory, Research & Practice TI - Physically unexplained chronic pain and its impact on children and their families: the mother's perception UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106589362&site=ehost-live&scope=site VL - 75 ID - 796 ER - TY - JOUR AB - Purpose: To prioritize outcome domains sensitive to the needs of the various stakeholders involved in rehabilitation programs designed for youth with pain-related disability using the International Classification of Function Child and Youth version. Materials and methods: A 5-step nominal group technique was conducted with 13 stakeholders, including two youth with pain-related disability, two parents, five clinicians, two teachers, and two healthcare managers. Once identified by content thematic analysis and International Classification of Function linking, 15 outcome domains were ranked. Priority rank scores were then weighted. Results: Six outcome domains were prioritized: (1) activities of daily living, (2) participation in meaningful activities, (3) social roles and relationships, (4) mood and affect, (5) school engagement, and (6) self-efficacy. Discrepancies in ranking existed; parents and youth attributed importance to pain, sleep, and program satisfaction whereas clinicians and mangers underscored pain-related fear and family functioning. When compared, prioritized domain associated with three PedIMMPACT recommendations and aligned with the activity and participation components of the International Classification of Function for Child and Youth. Conclusion: These findings emphasize the importance of integrating various perspectives, including those of youth with pain-related disability and other important stakeholders and adopting a broader conceptualization of disability and function when selecting key rehabilitation evaluation outcome for this population. The identification of value differences among stakeholder underscores the importance of engaging youths, their families and other stakeholders, such as teachers and health care managers in rehabilitation program evaluation. The consensus processes employed allowed for the reconciliation of the different priorities, and the achievement of agreement on participation in life and its related activities as a key desired outcome of rehabilitation programs for youth with pain-related disability. The use of the ICF-CY framework allowed a broader conceptualization of the rehabilitation outcome domains, and the examination of areas beyond reduction of pain, disability and impairment to include functional aspects such as self-care, daily routine and mobility activities, and meaningful participation in life, fostering social roles and responsibilities, and school engagement. As participation in life and its related tasks and activities were key outcomes for all stakeholders, they should be the focus of clinicians' treatment. AD - Facility of Medicine and Health Sciences, Univeristy of Sherbrooke, Sherbrooke, Quebec, Canada School of Public Administration, University of Victoria, Victoria, BC, Canada Department of Psychology, University of Calgary, Calgary, AB, Canada CanChild Centre for Childhood Disability Research, McMaster University, Hamilton, Canada AN - 144410963. Language: English. Entry Date: 20200711. Revision Date: 20200711. Publication Type: Article AU - Hurtubise, Karen AU - Brousselle, Astrid AU - Noel, Melanie AU - Camden, Chantal DB - cin20 DO - 10.1080/09638288.2018.1532462 DP - EBSCOhost IS - 12 KW - Chronic Pain -- Rehabilitation Stakeholder Participation Outcome Assessment Funding Source Human Female Male Adult Middle Age Content Analysis Thematic Analysis Activities of Daily Living Community Role Affect N1 - research; tables/charts. Journal Subset: Allied Health; Europe; Peer Reviewed; UK & Ireland. Grant Information: Vanier Doctoral Scholarship Award and the training programs Canadian Child Health Clinician Scientist Program, Pain in Child Health: Research Training Initiative.. NLM UID: 9207179. PY - 2020 SN - 0963-8288 SP - 1675-1686 ST - What really matters in pediatric chronic pain rehabilitation? Results of a multi-stakeholder nominal group technique study T2 - Disability & Rehabilitation TI - What really matters in pediatric chronic pain rehabilitation? Results of a multi-stakeholder nominal group technique study UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=144410963&site=ehost-live&scope=site VL - 42 ID - 184 ER - TY - JOUR AB - Managing post-operative pain continues to elude health care professionals despite children's reports of severe pain. Although research has demonstrated that guided imagery is a beneficial complementary treatment for pain, clinicians rarely incorporate it into their practice. This study evaluated the effectiveness of a guided imagery audio compact disc (CD) in reducing post-operative pain, increasing relaxation, and stimulating imagery in children by child life specialists in the clinical setting. This cross sectional study compared pain and relaxation scores before and after the use of the CD. Sixteen children (7 to 12 years of age) reported pain on a 0 to 10 scale and relaxation on a 1 to 5 scale, and answered questions about what they imagined. Pain scores were significantly decreased, with no significant differences in relaxation scores. Findings support that school-age children are capable of using guided imagery, and relaxation may not be necessary to achieve pain reduction. AD - Center for Professional Excellence-Research and Evidence-Based Practice, Cincinnati Children's Hospital Medical Center, Cincinnati, OH AN - 105334248. Language: English. Entry Date: 20091211. Revision Date: 20150818. Publication Type: Journal Article AU - Huth, M. M. AU - Daraiseh, N. M. AU - Henson, M. A. AU - McLeod, S. M. DB - cin20 DP - EBSCOhost IS - 5 KW - CD ROM Child, Hospitalized Guided Imagery -- In Infancy and Childhood Postoperative Pain -- Prevention and Control -- In Infancy and Childhood Child Content Validity Cross Sectional Studies Data Analysis Software Descriptive Statistics Education, Continuing (Credit) Female Male Pain Measurement Paired T-Tests Pretest-Posttest Design Questionnaires Relaxation Scales Spearman's Rank Correlation Coefficient Human N1 - research; tables/charts. Journal Subset: Core Nursing; Nursing; Peer Reviewed; USA. Instrumentation: Oucher Scale [Modified]. NLM UID: 7505804. PMID: NLM19916345. PY - 2009 SN - 0097-9805 SP - 290-295 ST - Evaluation of the Magic Island: Relaxation for Kids© compact disc T2 - Pediatric Nursing TI - Evaluation of the Magic Island: Relaxation for Kids© compact disc UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105334248&site=ehost-live&scope=site VL - 35 ID - 652 ER - TY - JOUR AB - Study Design: A controlled clinical trial.Objectives: To examine the long-term effect of an informative approach to low back pain.Summary Of Background Data: In management and prevention of low back pain, back school based on an ergonomic approach have played in important role. The effect of such informative interventions is not clear.Methods: A 5-year follow-up study was done on patients included in a previous study. The outcome was measured by return to work or still on sick leave. The patients were allocated to an intervention group (n = 245) and a control group (n = 244). Only the intervention group was called in for examination and intervention and answered a battery of tests for psychological and health factors. The intervention apart from the clinical examination consisted of education in an "mini back school." The program was based on a new medical model for low back pain.Results: Forty-seven (19%) of the patients in the intervention group, compared with 84 patients (34%) in the control group, were still on sick leave after 5 years (P < 0.001). There were fewer recurrences of sick leave (P < 0.03) in the intervention group than in the control group. Based on Internal Health Locus of Control, number of children, and income, 75% were correctly classified as nonreturners in the intervention group.Conclusions: This study indicates that subchronic low back pain may be managed successfully with an approach that includes clinical examination combined with information for patients about the nature of the problem, provided in a manner designed to reduce fear and give them reason to resume light activity. AD - Spine Clinic, Ostfold Central Hospital, Fredrikstad, Norway Spine Clinic, Ostfold Central Hospital, 1600 Fredrikstad, Norway; e-mail: aage.indahl@medisin.uio.no AN - 107169121. Language: English. Entry Date: 19990301. Revision Date: 20190818. Publication Type: journal article AU - Indahl, A. AU - Haldorsen, E. H. AU - Holm, S. AU - Reikeras, O. AU - Ursin, H. AU - Indahl, A. AU - Haldorsen, E. H. AU - Holm, S. AU - Reikerås, O. AU - Ursin, H. DB - cin20 DP - EBSCOhost IS - 23 KW - Low Back Pain -- Rehabilitation Job Re-Entry Prospective Studies Clinical Trials Work Capacity Evaluation Questionnaires Multidimensional Health Locus of Control Scales Data Analysis, Statistical Data Analysis Software Personality Tests Research Instruments Psychological Tests One-Way Analysis of Variance Chi Square Test Discriminant Analysis P-Value Physical Activity Adolescence Adult Middle Age Aged Male Female Funding Source Human N1 - clinical trial; research; tables/charts. Journal Subset: Allied Health; Biomedical; Peer Reviewed; USA. Instrumentation: Multidimensional Health Locus of Control Scale (LOC) (Wallston et al); Spielberger State-Trait Anxiety Inventory (STAI); Eysenck Personality Inventory; Graded Reduced Work Ability Scale; Ursin's Health Inventory. Grant Information: Supported in part by the Norwegian Ministry of Health and Social Affairs. NLM UID: 7610646. PMID: NLM9854762. PY - 1998 SN - 0362-2436 SP - 2625-2630 ST - Five-year follow-up study of a controlled clinical trial using light mobilization and an informative approach to low back pain T2 - Spine (03622436) TI - Five-year follow-up study of a controlled clinical trial using light mobilization and an informative approach to low back pain UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=107169121&site=ehost-live&scope=site VL - 23 ID - 831 ER - TY - JOUR AB - OBJECTIVE: The etiology and pathogenesis of migraine and other types of headache are still under discussion. An interaction of organic, psychological, and psychosocial factors is operative. In this study, we aimed to determine the prevalence of headache and its association with socioeconomic status among schoolchildren. STUDY DESIGN: A cross-sectional study was performed on 2669 schoolchildren via a parental questionnaire. Socioeconomic status was determined according to the Turkish socioeconomic status scale. RESULTS: The mean age of the students was 8.2 +/- 2.4 years. The headache prevalence was 46.2% (95% CI: 44.3-48.1). The prevalence of migraine was 3.4% (95% CI: 2.8-4.1), the prevalence of probable migraine was 8.7% (95% CI: 7.6-9.8), and that of non-migraine headache was 34.1% (95% CI: 32.3-35.9). Multivariate analysis revealed that older age, being a girl, having a family history of headache, and exposure to passive smoking at home were independently associated with headache. There was an inverse association between socioeconomic status and all 3 types of headaches after adjusting for age, sex, family history of headache, and presence of passive smoking. When the group with the lowest socioeconomic status was taken as the reference category, the odds ratios for the highest socioeconomic group were 0.33 (95% CI: 0.16-0.69, P = .003) for the migraine, 0.30 (95% CI: 0.11-0.89, P = .029) for the probable migraine, and 0.34 (95% CI: 0.16-0.72, P = 0.005) for the non-migraine headache. CONCLUSION: Headache is more common among children with lower socioeconomic groups. Social causation can play a role in the pathogenesis of headache. AD - Acibadem Hospital, Inonu Cad. Okur Sok. No:20 Kozyatagi/Istanbul, Turkey. AN - 105520082. Language: English. Entry Date: 20090814. Revision Date: 20200708. Publication Type: Journal Article AU - Isik, U. AU - Topuzoglu, A. AU - Ay, P. AU - Ersu, R. H. AU - Arman, A. R. AU - Önsüz, M. F. AU - Karavus, M. AU - Dagl, E. DB - cin20 DO - 10.1111/j.1526-4610.2009.01339.x DP - EBSCOhost IS - 5 KW - Headache -- Epidemiology -- In Infancy and Childhood Socioeconomic Factors -- Evaluation -- Turkey Adolescence Chi Square Test Child Child, Preschool Confidence Intervals Cross Sectional Studies Data Analysis Software Data Analysis, Statistical Descriptive Statistics Female Kruskal-Wallis Test Male Migraine -- Epidemiology Multiple Logistic Regression Odds Ratio P-Value Passive Smoking -- Epidemiology Questionnaires Turkey Human N1 - research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 2985091R. PMID: NLM19175424. PY - 2009 SN - 0017-8748 SP - 697-703 ST - The prevalence of headache and its association with socioeconomic status among schoolchildren in Istanbul, Turkey T2 - Headache: The Journal of Head & Face Pain TI - The prevalence of headache and its association with socioeconomic status among schoolchildren in Istanbul, Turkey UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105520082&site=ehost-live&scope=site VL - 49 ID - 660 ER - TY - JOUR AB - Background Adolescent girls in Nigeria experience a disproportionately high burden of sexual and reproductive health disparities that affect their well-being. Yet, little is known about adolescent girls' own unique perspectives of the sexual and reproductive health challenges they face, and possible solutions to these challenges. Aims To explore top sexual and reproductive health concerns of female adolescents in Nigeria and their perceptions regarding potential solutions to these issues. Methods Eighty adolescent girls attending two public secondary schools in Lagos, Nigeria completed individual free-listing interviews. Items assessed their perceptions of the most important sexual and reproductive health issues and potential solutions to these issues at the individual and societal level. Data were analyzed using Anthropac 4.98 to sort the lists by item frequency as well as to determine Smith's salience index (S). Results The top five sexual and reproductive health concerns identified by participants were human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS), followed by menstrual pain, vaginal infections, sexual abuse and teenage pregnancy. Adolescent girls stated that youth empowerment programs that provide access to skills-building opportunities and mentors was one potential strategy for addressing their sexual and reproductive health priorities. Other solutions identified were access to medical checkups, general health talks focused on their sexual and reproductive health concerns as well as access to health facilities and opportunities to build self-efficacy skills. Conclusion Adolescent girls in Nigeria need to be engaged in becoming powerful agents in improving their own sexual and reproductive health, and in crafting solutions that may be effective in enabling them to achieve their full potential and rights to health and well-being. The findings will be used to develop an intervention targeting the sexual and reproductive health priorities of adolescent girls in Lagos, Nigeria. AD - Department of Kinesiology and Community Health, College of Applied Health Sciences, University of Illinois at Urbana-Champaign, 1206 S.4th, Champaign, IL, 61822, USA Department of Kinesiology and Community Health, College of Applied Health Sciences, University of Illinois at Urbana-Champaign, Champaign, IL, USA Department of Health Promotion, Education, and Behavior, University of South Carolina, Columbia, SC, USA Morning Star Health and Human Development Foundation, Festac Town, Lagos, Nigeria Department of Health Promotion Sciences, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, USA AN - 132824437. Language: English. Entry Date: 20190209. Revision Date: 20200602. Publication Type: journal article. Journal Subset: Biomedical AU - Iwelunmor, Juliet AU - Blackstone, Sarah AU - Nwaozuru, Ucheoma AU - Conserve, Donaldson AU - Iwelunmor, Patricia AU - Ehiri, John E. DB - cin20 DO - 10.1515/ijamh-2016-0105 DP - EBSCOhost IS - 5 KW - Attitude to Health Reproductive Health Sexuality Sex Education -- Statistics and Numerical Data Young Adult Schools Adolescence Nigeria Health Services Needs and Demand -- Statistics and Numerical Data Adolescent Behavior Female N1 - Middle East; Peer Reviewed. NLM UID: 8506960. PMID: NLM28525320. PY - 2018 SN - 0334-0139 SP - N.PAG-N.PAG ST - Sexual and reproductive health priorities of adolescent girls in Lagos, Nigeria: findings from free-listing interviews T2 - International Journal of Adolescent Medicine & Health TI - Sexual and reproductive health priorities of adolescent girls in Lagos, Nigeria: findings from free-listing interviews UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=132824437&site=ehost-live&scope=site VL - 30 ID - 284 ER - TY - JOUR AB - Sickle cell anemia is a genetic disorder that affects 1 in 600 black infants in the United States. The painful crisis is one of its most characteristic manifestations and consists of pain in the extremities, back, abdomen, or chest. It may occur in 4 phases and may be precipitated by a variety of factors. The frequency, location, duration, severity, and character of pain differ both within and among patients. The pain may be localized, involve several areas, be diffuse, or be migratory. The intensity of pain varies from mild to excruciating and is perceived to be more intense by those who have experienced other forms of pain such as postoperative pain. Patients with sickle cell anemia who experience frequent painful crises exhibit problems with self-concept and low self-esteem, anxiety, depression, dissatisfaction with body image, poor school performance, social isolation, decreased participation in normal activities of daily living, and poor peer and family relationships. The periodic and unpredictable episodes can be incapacitating and may affect the way children see and feel about themselves, the way they relate to other people, the goals they set for themselves, and the way they approach a range of activities and situations. Research is very limited, and most of the available literature is based on personal observations, opinions, and anecdotal reports. The purpose of this report is to describe the phases of a painful episode as well as to examine the predisposing factors to, defining characteristics of, and patient outcomes associated with a painful crisis from sickle cell anemia. Copyright © 2001 by W.B. Saunders Company AD - Hematology/Oncology Unit, Children's Hospital Oakland, Oakland, CA. E-mail: ejacob@samuelmerritt.edu AN - 106895112. Language: English. Entry Date: 20020125. Revision Date: 20150820. Publication Type: Journal Article AU - Jacob, E. DB - cin20 DP - EBSCOhost IS - 3 KW - Anemia, Sickle Cell Pain Pain -- Physiopathology Pain -- Etiology Pain -- Psychosocial Factors Bone Marrow -- Pathology Time Factors Anemia, Sickle Cell -- Physiopathology Child, Preschool Child Adolescence Adult N1 - pictorial; review; tables/charts. Journal Subset: Blind Peer Reviewed; Core Nursing; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 100890606. PMID: NLM11710089. PY - 2001 SN - 1524-9042 SP - 74-83 ST - The pain experience of patients with sickle cell anemia T2 - Pain Management Nursing TI - The pain experience of patients with sickle cell anemia UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106895112&site=ehost-live&scope=site VL - 2 ID - 810 ER - TY - JOUR AB - Objectives: Beneficial therapeutic effect of probiotics has been reported in children with the irritable bowel syndrome (IBS) but not consistently in other functional abdominal pain-related disorders. The aim of the present study was to investigate the effect of Lactobacillus reuteri DSM 17938 in the treatment of functional abdominal pain (FAP) and IBS in children.Methods: Children (age 4-18 years) referred to pediatric gastroenterologist at Children's Hospital Zagreb from May 2012 to December 2014, diagnosed as FAP or IBS, were randomized to receive L reuteri DSM 17938 10⁸ CFU daily or placebo. The study was a prospective, randomized, double-blind, placebo-controlled parallel study. Symptoms were evaluated using Wong-Baker FACES pain rating scale for pain and Bristol scale for stool shape and consistence.Results: Data were analyzed for 55 children (26 in the intervention group and 29 in the placebo group). Children in the intervention group had significantly more days without pain (median 89.5 vs 51 days, P = 0.029). Abdominal pain was less severe in children taking probiotics during the second month (P < 0.05) and fourth month (P < 0.01). The 2 groups did not differ in the duration of abdominal pain, stool type, or absence from school. Both groups experienced significant reduction in the severity of abdominal pain from first to fourth month, with the reduction more prominent in the intervention group (P < 0.001 vs P = 0.004).Conclusions: Administration of L reuteri DSM 17938 was associated with a possible reduction of the intensity of pain and significantly more days without pain in children with FAP and IBS. AD - Referral Center for Pediatric Gastroenterology and Nutrition, Children's Hospital Zagreb, Croatia Center for Pediatric Medicine "Helena", Zagreb, Croatia AN - 123059725. Language: English. Entry Date: 20180309. Revision Date: 20190105. Publication Type: journal article AU - Jadrešin, Oleg AU - Hojsak, Iva AU - Mišak, Zrinjka AU - Kekez, Alemka Jaklin AU - Trbojević, Tena AU - Ivković, Lana AU - Kolaček, Sanja DB - cin20 DO - 10.1097/MPG.0000000000001478 DP - EBSCOhost IS - 6 KW - Probiotics -- Therapeutic Use Abdominal Pain -- Therapy Lactobacillus Irritable Bowel Syndrome -- Therapy Recurrence Child, Preschool Child Chronic Disease Treatment Outcomes Prospective Studies Double-Blind Studies Adolescence Human Severity of Illness Indices Female Male Validation Studies Comparative Studies Evaluation Research Multicenter Studies Randomized Controlled Trials Wong-Baker FACES Pain Rating Scale Scales Random Assignment N1 - research; randomized controlled trial. Journal Subset: Allied Health; USA. Special Interest: Evidence-Based Practice. Instrumentation: Wong-Baker FACES Pain Rating Scale; Bristol Scale. NLM UID: 8211545. PMID: NLM27906800. PY - 2017 SN - 0277-2116 SP - 925-929 ST - Lactobacillus reuteri DSM 17938 in the Treatment of Functional Abdominal Pain in Children: RCT Study T2 - Journal of Pediatric Gastroenterology & Nutrition TI - Lactobacillus reuteri DSM 17938 in the Treatment of Functional Abdominal Pain in Children: RCT Study UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=123059725&site=ehost-live&scope=site VL - 64 ID - 363 ER - TY - JOUR AB - Youth with chronic pain and youth who have experienced stressors are at risk for poor outcomes; however, little is known about the intersection of pain and stressors. This study aims to understand the prevalence of stressors among youth with chronic pain and the relationship between stressors and pain-related outcomes. Seven hundred and seventy youth with chronic pain aged 8-18 (Mage = 14.15 years, 70% female) reported pain characteristics, stressors, anxiety, disability, and quality of life. Most participants (82%) endorsed at least one stressor. A greater number of stressors was significantly related to greater anxiety and disability, and lower levels of quality of life. School stressors were significantly associated with functional disability; family, school, and peer stressors were significantly associated with anxiety and quality of life. Stressors are common in youth with chronic pain, and the presence of stressors is related to greater functional impairment. The results of this preliminary study using semi-structured clinical interviews suggest the importance of developing a validated measure that encompasses a wide variety of stressors for youth with pain. Future research on patient-reported stressors, relative intensity, and impact are needed. AD - Department of Psychology, DePaul University, Chicago, IL 60614, USA Department of Anesthesiology, Medical College of Wisconsin, Wauwatosa, WI 53226, USA College of Osteopathic Medicine, Pacific Northwest University of Health Sciences, Yakima, WA 98901, USA Nemours/AI duPont Hospital for Children, Wilmington, DE 19803, USA Children's Hospital of Wisconsin, Medical College of Wisconsin, Milwaukee, WI 53226, USA AU - Jagpal, Anjana AU - Hainsworth, Keri AU - Galijot, Ratka AU - Salamon, Katherine S. AU - Khan, Kim Anderson AU - Tran, Susan T. DB - cin20 DO - 10.3390/children8010021 DP - EBSCOhost IS - 1 N1 - Accession Number: 148271572. Language: English. Entry Date: In Process. Revision Date: 20210126. Publication Type: Article. PY - 2021 SN - 2227-9067 SP - 1-11 ST - The Relationship between Stressors and Pain-Related Clinical Outcomes in Pediatric Chronic Pain Patients T2 - Children TI - The Relationship between Stressors and Pain-Related Clinical Outcomes in Pediatric Chronic Pain Patients UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=148271572&site=ehost-live&scope=site VL - 8 ID - 153 ER - TY - JOUR AB - ISSUES AND PURPOSE: Review the etiology and pathophysiology of recurrent abdominal pain (RAP) and its potential role as a precursor to irritable bowel syndrome (IBS) in adults. CONCLUSIONS: Physiological mechanisms not easily identifiable as an organic cause may underlie symptoms in RAP patients. They may be triggered by psychosocial factors that result in greater functional disability, more clinic visits, and lower academic and social competence. Of these children, 25% will experience similar symptoms as adults; many will be diagnosed with IBS. PRACTICE IMPLICATIONS: Nurses can provide early and efficient management of these children's care if they view the issues of abdominal pain/discomfort from a broader focus that includes the context of the child's experiences. AN - 106719046. Language: English. Entry Date: 20040402. Revision Date: 20150820. Publication Type: Journal Article. Journal Subset: Core Nursing AU - Jarrett, M. AU - Heitkemper, M. AU - Czyzewski, D. I. AU - Shulman, R. DB - cin20 DP - EBSCOhost IS - 3 KW - Abdominal Pain -- Etiology -- In Infancy and Childhood Child Recurrence Gastrointestinal Motility Abdominal Pain -- Psychosocial Factors -- In Infancy and Childhood Abdominal Pain -- Nursing Abdominal Pain -- Physiopathology -- In Infancy and Childhood Pediatric Nursing Irritable Bowel Syndrome Adult N1 - Nursing; Peer Reviewed; USA. NLM UID: 101142025. PMID: NLM12942886. PY - 2003 SN - 1539-0136 SP - 81-89 ST - Recurrent abdominal pain in children: forerunner to adult irritable bowel syndrome? T2 - Journal for Specialists in Pediatric Nursing TI - Recurrent abdominal pain in children: forerunner to adult irritable bowel syndrome? UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106719046&site=ehost-live&scope=site VL - 8 ID - 785 ER - TY - JOUR AB - AbstractObjective:Treatment-resistant depression (TRD) imposes substantial cost from the perspective of employers. The objective of this study was to assess direct healthcare costs and indirect (disability and medical-related absenteeism) costs associated with TRD compared with non-treatment-resistant major depressive disorder (MDD).Methods:Employees with one or more inpatient, or two or more outpatient/other MDD diagnoses (ICD-9-CM: 296.2x, 296.3x) from 2004 through 2007, ages 18–63 years, were selected from a claims database. Employees who initiated a third antidepressant following two antidepressant treatments of adequate dose and duration or who met published TRD criteria were classified as TRD likely (N  2312). The index date was the date of the first antidepressant, starting 1/1/2004. The control group was an age- and sex-matched cohort of employees with MDD but without TRD. All had continuous eligibility during the 6-month pre-index (baseline) and 24-month post-index (study) period. McNemar tests were used to compare baseline comorbidities. Wilcoxon signed-rank tests were used to compare costs from employer perspective.Results:TRD-likely employees were on average 48 years old, and 64.8 were women. Compared with MDD controls, TRD-likely employees had significantly higher rates of mental-health disorders, chronic pain, fibromyalgia, and higher Charlson Comorbidity Index. Average direct 2-year costs were significantly higher for TRD-likely employees (22,784) compared with MDD controls (11,733), p < 0.0001. Average indirect costs were also higher among TRD-likely employees (12,765) compared with MDD controls (6885), p < 0.0001.Limitations:Limitations of claims data related to accuracy of diagnosis coding and lack of clinical information apply to this study.Conclusions:Based on comorbidities and healthcare resources used, patients with TRD appeared to represent a clinically complex subgroup of individuals with MDD. TRD was associated with significant cost burden. AN - 104886737. Language: English. Entry Date: 20110802. Revision Date: 20200708. Publication Type: Journal Article AU - Jasmina, I. Ivanova AU - Howard, G. Birnbaum AU - Yohanne, Kidolezi AU - Ganesh, Subramanian AU - Sajjad, A. Khan AU - Michael, D. Stensland DB - cin20 DO - 10.1185/03007995.2010.517716 DP - EBSCOhost IS - 10 KW - Depression -- Therapy Depression -- Economics Drug Resistance Business -- Economics Human Clinical Assessment Tools McNemar's Test Wilcoxon Signed Rank Test Absenteeism Adolescence Adult Antidepressive Agents -- Economics Antidepressive Agents -- Therapeutic Use Comorbidity Depression -- Epidemiology Employment Female Health Resource Utilization Male Middle Age N1 - research. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. Instrumentation: Charlson Comorbidity Index (CCI). NLM UID: 0351014. PMID: NLM20825269. PY - 2010 SN - 0300-7995 SP - 2475-2484 ST - Direct and indirect costs of employees with treatment-resistant and non-treatment-resistant major depressive disorder T2 - Current Medical Research & Opinion TI - Direct and indirect costs of employees with treatment-resistant and non-treatment-resistant major depressive disorder UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104886737&site=ehost-live&scope=site VL - 26 ID - 610 ER - TY - JOUR AB - Adolescents with chronic pain often suffer significant impairment in physical, emotional, and social domains. Surprisingly little is known about executive functioning (EF) in youth with chronic pain or how EF deficits may contribute to functional impairment. Study participants included 60 adolescents between the ages of 12 and 17 years (M = 14.57). Thirty participants with chronic musculoskeletal pain and 30 age- and gender-matched healthy controls were recruited from a large Midwestern children’s hospital in the United States. Participants completed the Behavior Rating Inventory of Executive Functioning (BRIEF-2) as well as multiple measures of functional impairment across key domains: school, social, emotional (anxiety, depression), and physical. Adolescents with chronic musculoskeletal pain reported significantly greater EF impairment compared to healthy ageand gender-matched peers. Clinically elevated risk levels of impairment were reported across all aspects of EF, with many adolescents in the chronic pain group scoring above the clinical risk cut off for working memory (52%), inhibition (45%), and cognitive flexibility (38%). EF was also significantly related to functional impairment across all domains. Findings suggest that EF may have an impact across several critical domains of functioning for youth with chronic pain. AD - Department of Cell Biology, New York University Medical Center, New York, New York, U.S.A AU - Jastrowski Mano, Kristen E. AU - Beckmann, Emily A. AU - Fussner, Lauren M. AU - Kashikar-Zuck, Susmita DB - cin20 DO - 10.3390/children7120273 DP - EBSCOhost IS - 12 N1 - Accession Number: 147763566. Language: English. Entry Date: In Process. Revision Date: 20201228. Publication Type: Article. PY - 2020 SN - 2227-9067 SP - 1-12 ST - Executive Functioning in Adolescents with Chronic Musculoskeletal Pain T2 - Children TI - Executive Functioning in Adolescents with Chronic Musculoskeletal Pain UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=147763566&site=ehost-live&scope=site VL - 7 ID - 158 ER - TY - JOUR AB - The development and maintenance of pediatric chronic pain and anxiety are complex, underscoring the need to better understand the interactive forces contributing to their co-occurrence. The shared vulnerability model (SVM) was developed to explain the co-occurrence of chronic pain and posttraumatic stress disorder in adults. Although many core tenets have been well supported by pediatric research, the SVM has yet to be extended to pediatric pain populations. We propose a developmentally informed pediatric SVM for advancing our understanding of the co-occurrence of pediatric chronic pain and anxiety disorders. The proposed SVM postulates that youth at increased risk for the development of chronic pain and/or anxiety share predisposing vulnerabilities, including anxiety sensitivity, and that these shared vulnerabilities give rise to negative emotional responses (child and parent) in the context of stressful events. Consequences of fear and anxiety, including avoidance behavior, further contribute to the development of chronic pain, anxiety, and their co-occurrence. The parental, school, and peer contexts in which these problems develop and are maintained in youth are pertinent to integrate into a SVM, as pediatric chronic pain and anxiety disorders share several social-contextual risk and maintenance factors. We also highlight new areas of inquiry. AD - Department of Psychology, University of Cincinnati, Cincinnati, OH AN - 139566213. Language: English. Entry Date: In Process. Revision Date: 20201112. Publication Type: journal article AU - Jastrowski Mano, Kristen E. AU - O'Bryan, Emily M. AU - Gibler, Robert C. AU - Beckmann, Emily DB - cin20 DO - 10.1097/AJP.0000000000000763 DP - EBSCOhost IS - 12 KW - Chronic Pain -- Complications Models, Theoretical Anxiety -- Complications Adolescence Chronic Pain -- Psychosocial Factors Child Anxiety -- Psychosocial Factors Male Child, Preschool Female Social Readjustment Rating Scale N1 - review. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Instrumentation: Social Readjustment Rating Scale (SRRS) (Holmes and Rahe). NLM UID: 8507389. PMID: NLM31513056. PY - 2019 SN - 0749-8047 SP - 989-1002 ST - The Co-occurrence of Pediatric Chronic Pain and Anxiety: A Theoretical Review of a Developmentally Informed Shared Vulnerability Model T2 - Clinical Journal of Pain TI - The Co-occurrence of Pediatric Chronic Pain and Anxiety: A Theoretical Review of a Developmentally Informed Shared Vulnerability Model UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=139566213&site=ehost-live&scope=site VL - 35 ID - 206 ER - TY - JOUR AB - Sri Lanka is a resource-poor country in the South-East Asian region with good health indices. Ergonomics of children in educational environments is still novel in the region. An exploration into such issues and dissemination of the scientific evidence will stimulate policy makers in both education and health sector. An important ergonomic issue of the classroom is the seating arrangement. Essential aspects of seating include location of the chair and desk in relation to the blackboard and features of the chair and desk. Musculoskeletal pain is considered to be the most important negative effect due to mismatched ergonomics. A school-based descriptive cross sectional study was carried out in a district of Sri Lanka to ascertain the distribution of selected ergonomic factors related to seating arrangements in the classroom of school-going early adolescents and to assess their relationship to musculoskeletal pain. A sample of 1607 school children of Grade 6,7 and 8 were selected using stratified multi-stage cluster sampling method. There were 52.1% (N=838) females and 47.9% (N=769) males. Many ergonomic aspects related to classroom seating arrangements are not conducive for children. Children were seated with a mean distance of 398.04 cm (SD=132.09) to the blackboard. Nearly 23% of children had to turn more than 45 degrees to see the blackboard. A prevalence of > 80% mismatch was found between body dimensions of children and measurements of furniture. Musculoskeletal pain may have resulted from efforts to maintain stability while seated in incompatible furniture. Nearly 36% children complained of recurrent musculoskeletal pain. Musculoskeletal pain may have resulted from efforts to maintain stability while seated in incompatible furniture. Mismatched seat depth - buttock-popliteal length posed 1.59 times risk recurrent musculoskeletal pain. Despite, children perceived a good chair comfort. Use of backrest lowered the risk of recurrent pain. Results shows that programme planners can utilize such evidence to provide simple ergonomic solutions at national and school level. AD - Integrated Systems Engineering, The Ohio State University, Columbus, OH, USA AN - 105291852. Language: English. Entry Date: 20100129. Revision Date: 20200708. Publication Type: Journal Article AU - Jayaratne, I. AU - Fernando, D. N. DB - cin20 DO - 10.3233/WOR-2009-0941 DP - EBSCOhost IS - 4 KW - Ergonomics Musculoskeletal Diseases Adaptive Seating Adolescence Coefficient Alpha Cross Sectional Studies Descriptive Statistics Funding Source Human Policy Making School Health Schools Sri Lanka Students Visual Analog Scaling N1 - pictorial; research; tables/charts. Journal Subset: Allied Health; Europe; Peer Reviewed; UK & Ireland. Grant Information: Family Health Bureau and Health Sector Development Project -- World Bank under the Ministry of Health, Sri Lanka. NLM UID: 9204382. PMID: NLM20075518. PY - 2009 SN - 1051-9815 SP - 409-420 ST - Ergonomics related to seating arrangements in the classroom: worst in South East Asia? The situation in Sri Lankan school children T2 - Work TI - Ergonomics related to seating arrangements in the classroom: worst in South East Asia? The situation in Sri Lankan school children UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105291852&site=ehost-live&scope=site VL - 34 ID - 643 ER - TY - JOUR AB - OBJECTIVE: To examine perceived independence, overprotection, and support, and their association with the employment participation of young adults with rheumatic disease. METHODS: One hundred and forty-three young adults, ages 18 to 30 years, with systemic lupus erythematosus (54.5%) and juvenile arthritis (45.5%) completed a 30-min online questionnaire of their work and education experiences. Information collected was demographic, health (e.g., pain, fatigue, disease activity), work context (e.g., career satisfaction, helpfulness of job accommodation/benefits, and workplace activity limitations), and psychosocial (e.g., independence, social support, and overprotection). Log-Poisson regression analysis examined factors associated with employment status. RESULTS: Over half of respondents were employed (59%) and 26% were enrolled in school. Respondents reported moderate to high perceptions of independence and social support. However, 27% reported that 'quite a bit' to 'a great deal' of overprotection characterized their relationships with those closest to them. At the bivariate level, employed participants and those indicating greater perceived independence reported greater social support and less overprotection. Multivariable analysis revealed that being employed was associated with older age, more job accommodations/benefits perceived as being helpful, and greater perceived independence. CONCLUSION: This is one of the first studies examining the employment of young adults with rheumatic diseases. Findings highlight the importance of psychosocial perceptions such as independence and overprotection, in addition to support related to working. Additional research is needed to better understand the role of those close to young adults with rheumatic diseases in supporting independence and encouraging employment. AN - 109766807. Language: English. Entry Date: 20150605. Revision Date: 20200708. Publication Type: Journal Article AU - Jetha, Arif AU - Badley, Elizabeth AU - Beaton, Dorcas AU - Fortin, Paul R. AU - Shiff, Natalie J. AU - Rosenberg, Alan M. AU - Tucker, Lori B. AU - Mosher, Dianne P. AU - Gignac, Monique A. M. DB - cin20 DO - 10.3899/jrheum.140419 DP - EBSCOhost IS - 12 KW - Arthritis, Juvenile Rheumatoid -- Psychosocial Factors Employment -- Psychosocial Factors Community Living -- Psychosocial Factors Lupus Erythematosus, Systemic -- Psychosocial Factors Rheumatic Diseases -- Psychosocial Factors Adult Data Collection Female Human Male Parents -- Psychosocial Factors Probability Psychology Questionnaires Regression Perception Support, Psychosocial Young Adult N1 - research. Journal Subset: Biomedical; Blind Peer Reviewed; Canada; Continental Europe; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. NLM UID: 7501984. PMID: NLM25274887. PY - 2014 SN - 0315-162X SP - 2386-2394 ST - Transitioning to employment with a rheumatic disease: the role of independence, overprotection, and social support T2 - Journal of Rheumatology TI - Transitioning to employment with a rheumatic disease: the role of independence, overprotection, and social support UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=109766807&site=ehost-live&scope=site VL - 41 ID - 468 ER - TY - JOUR AB - Purpose: The number of adolescents experiencing pain is increasing. Pain has a major impact on several areas of daily living, such as function at school and school absenteeism, loss of appetite and socializing. One out of ten pupils in Norwegian schools is immigrants, and surveys have shown that immigrants suffer from poor health more often than the general population. The purpose of this study was to explore how school nurses and teachers experience pain in young immigrants in the school setting. Design/methodology/approach: A qualitative design using focus group interviews was chosen for data collection. A total of 11 focus groups (17 school nurses and 25 teachers) consisting of school nurses and teachers in junior high schools (age: 13-16 years) in Southern Norway were conducted. Data were analyzed using a qualitative content analysis. Findings: School nurses and teachers experienced communication of pain with young immigrants as characterized by cultural differences and language problems. Immigrants waiting for residency permits experienced pain more often than others. They also experienced that young immigrants often were absent from school and used pain as an excuse for not participating in classes, but this was not the case at the special school for immigrants. During Ramadan, they experienced that immigrant pupils had an increase of pain, especially headaches. Originality/value: Culture affects the assessment and management of pain and different strategies may assist school nurses and teachers in their encounter with young immigrants with pain. There is a need for education in cultural competence among teachers and school nurses. AD - Department of Health and Nursing Science, University of Agder, Norway, Norway Faculty of Health and Sport Sciences, University of Agder, Kristiansand, Norway Oslo Metropolitan University, Norway and Faculty of Health and Sport Sciences, University of Agder, Kristiansand, Norway AN - 142008531. Language: English. Entry Date: 20200306. Revision Date: 20200306. Publication Type: Article AU - Johannessen, Berit AU - Hoie, Magnhild AU - Haraldstad, Kristin AU - Helseth, Solvi AU - Fegran, Liv AU - Westergren, Thomas AU - Slettebø, Åshild AU - Rohde, Gudrun DB - cin20 DO - 10.1108/IJMHSC-01-2019-0005 DP - EBSCOhost IS - 1 KW - Nurse Attitudes -- Norway Teachers -- Psychosocial Factors -- Norway Immigrants -- Psychosocial Factors -- Norway Pain Management -- In Adolescence -- Norway Learning Environment -- Norway Human Norway Adolescence Qualitative Studies Focus Groups Interviews Schools, Middle Communication Content Analysis Cultural Diversity Language Headache -- Prevention and Control Cultural Competence N1 - research; tables/charts. Journal Subset: Biomedical; Europe; UK & Ireland. NLM UID: 101480334. PY - 2020 SN - 1747-9894 SP - 1-11 ST - School nurses' and teachers' perceptions of pain in young immigrants living in Norway T2 - International Journal of Migration, Health & Social Care TI - School nurses' and teachers' perceptions of pain in young immigrants living in Norway UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=142008531&site=ehost-live&scope=site VL - 16 ID - 202 ER - TY - JOUR AB - OBJECTIVE: Low back pain (LBP) is common in children but the prognostic indicators are poorly understood. We report the results of a prospective study to determine the risk factors for chronic LBP in children. METHODS: A total of 330 children with LBP were identified from a cross-sectional survey in schools in Northwest England. Data were collected by self-completion questionnaire on a number of potential risk factors for LBP persistence, including lifestyle factors, the occurrence of other symptoms, behavioral and emotional characteristics, and symptom severity and duration. Participants were then followed over the following 4 years to determine persistent symptoms. RESULTS: Complete followup data were available from 178 children, of whom 46 (26%) reported persistent LBP. Forward stepwise Poisson regression identified 5 independent predictors of pain persistence: peer relationship problems, being of smaller stature, the prior report of widespread body pain, long duration of LBP episodes, and radiating leg pain. Of children with none of these factors at baseline, <5% went on to report persistent LBP. In contrast, of those with 4 or 5 factors, nearly 80% experienced persistent symptoms. CONCLUSION: Although childhood consultations for LBP are infrequent, we have shown that approximately 25% of children 11-14 years of age with LBP still report symptoms 4 years later. These children can be identified early by a combination of clinical markers and etiologic factors. This provides a basis for considering interventions for secondary prevention; the challenge will be to determine whether we can intervene to alter symptom trajectory at an early stage. AD - Aberdeen Pain Research Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, UK. AN - 105326453. Language: English. Entry Date: 20091127. Revision Date: 20200708. Publication Type: Journal Article AU - Jones, G. T. AU - Macfarlane, G. J. DB - cin20 DO - 10.1002/art.24696 DP - EBSCOhost IS - 10 KW - Low Back Pain -- Diagnosis Low Back Pain -- Epidemiology Activities of Daily Living Adolescence Child Female Great Britain Life Style Low Back Pain -- Physiopathology Male Predictive Value of Tests Prognosis Prospective Studies Questionnaires Risk Factors Human N1 - research. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 0370605. PMID: NLM19790124. PY - 2009 SP - 1359-1366 ST - Predicting persistent low back pain in schoolchildren: A prospective cohort study T2 - Arthritis & Rheumatism: Arthritis Care & Research TI - Predicting persistent low back pain in schoolchildren: A prospective cohort study UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105326453&site=ehost-live&scope=site VL - 61 ID - 646 ER - TY - JOUR AB - OBJECTIVE: To determine factors associated with, and the predictors of, widespread body pain in children. METHODS: A population-based prospective study was conducted among school children in Northwest England. At baseline, subjects completed a self-report questionnaire on widespread body pain. Information was collected on behavioral and emotional factors, other somatic symptoms, and measures of physical activity/inactivity. Children who were free of widespread pain were contacted again 12 months later to determine any new onset of widespread pain. Regression analyses were used to identify the factors that were associated with the reporting of widespread pain at baseline, and to determine the factors that predicted the new onset of symptoms at followup among those children free of widespread pain at baseline. Results were expressed as relative risks (RR) with 95% confidence intervals (95% CI). RESULTS: A total of 1,440 children (96%) agreed to participate in the survey at baseline, and of those eligible, 1,081 (88%) participated at followup. The reporting of widespread pain (prevalence 14.6%) and its new onset at the 12-month followup (prevalence 7.7%) was common. At baseline, symptoms were associated with adverse behavioral and emotional factors (RR 2.5, 95% CI 1.8-3.6), with the report of other common childhood somatic symptoms (e.g., frequent headache; RR 3.5, 95% CI 2.2-5.5), and with high levels of sports activity (RR 1.9, 95% CI 1.3-2.9). Furthermore, all of these factors (in the absence of widespread pain at baseline) increased the likelihood of symptom onset at followup. CONCLUSION: Children who report behavioral problems or other somatic symptoms are at increased risk, at least in the short term, of developing chronic widespread pain. It remains to be determined whether these are long-term risk factors for the onset of such symptoms, and whether they could be predictors of the development of other functional syndromes. AD - Unit of Chronic Disease Epidemiology, University of Manchester, Manchester, UK AN - 106668733. Language: English. Entry Date: 20041126. Revision Date: 20200708. Publication Type: Journal Article AU - Jones, G. T. AU - Silman, A. J. AU - Macfarlane, G. J. DB - cin20 DO - 10.1002/art.11221 DP - EBSCOhost IS - 9 KW - Pain -- Epidemiology -- In Infancy and Childhood Adolescence Child Child Behavior Disorders -- Complications Confidence Intervals Cross Sectional Studies Female Male Pain -- Psychosocial Factors Pain -- Risk Factors Physical Activity Prospective Studies Questionnaires Relative Risk Somatoform Disorders -- Complications Funding Source Human N1 - research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. Grant Information: Supported by the Colt Foundation, the Medical Research Council, UK, and the Arthritis Research Campaign, Chesterfield, UK. NLM UID: 0370605. PMID: NLM13130481. PY - 2003 SN - 0004-3591 SP - 2615-2621 ST - Predicting the onset of widespread body pain among children T2 - Arthritis & Rheumatism TI - Predicting the onset of widespread body pain among children UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106668733&site=ehost-live&scope=site VL - 48 ID - 781 ER - TY - JOUR AB - School is often cited as the 'work of childhood' and serves as an important site for child and adolescent development. Frequent school absences in children and adolescents with chronic pain are well documented; however, variables that may explain school impairment are not understood. The potential consequences of school impairment are extensive, as these children and adolescents are at great risk for achieving poor grades and sometimes require full-time homebound instruction. This, in turn, can have adverse effects on occupational and social functioning well into adulthood. The present review provides a summary of selected studies that have investigated why children and adolescents with chronic pain may experience disruptions in school functioning. A conceptual model of school functioning is presented to summarize factors accumulated to date and to guide future investigations. AD - Werklund School of Education, Educational Psychology, University of Calgary, Canada, T2N 1N4 Hotchkiss Brain Institute, Full Member, University of Calgary, Canada, T2N 1N4 Department of Psychology, University of Calgary, Canada, T2N 1N4 Alberta Children's Hospital Research Institute, Full Member, Alberta Children's Hospital, Canada, T2N 1N4 AN - 128567819. Language: English. Entry Date: 20180403. Revision Date: 20180403. Publication Type: Article AU - Jones, Kailyn AU - Nordstokke, David AU - Wilcox, Gabrielle AU - Schroeder, Meadow AU - Noel, Melanie DB - cin20 DO - 10.2217/pmt-2017-0048 DP - EBSCOhost IS - 2 KW - Chronic Pain -- Psychosocial Factors -- In Adolescence Academic Performance Models, Theoretical Adolescence Child N1 - review; tables/charts. Journal Subset: Biomedical; Europe; UK & Ireland. NLM UID: 101555934. PY - 2018 SN - 1758-1869 SP - 139-153 ST - The 'work of childhood': understanding school functioning in youth with chronic pain T2 - Pain Management TI - The 'work of childhood': understanding school functioning in youth with chronic pain UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=128567819&site=ehost-live&scope=site VL - 8 ID - 316 ER - TY - JOUR AB - During the past 30 years, there has been an increase in the incidence of cancer in adolescents. While recent studies have illustrated remarkable resilience in youth living with cancer, they can also face daunting acute and chronic adjustment struggles, cognitive and school problems, family and peer relational difficulties, depression, post-traumatic stress symptoms, and other anxiety disorders. Mindfulness-based interventions (MBIs), increasingly shown to be effective in a variety of medical and mental health settings, may be particularly beneficial for adolescents with cancer. This paper reviews evidence from clinical trials of MBIs showing a variety of benefits for adult cancer patients, adolescents with anxiety disorders and chronic pain, and clinically healthy teenagers, which collectively point to likely benefits of MBIs for teen cancer patients. The authors also explore ways that the particular psychological problems often faced by teen cancer patients, including anxiety about the future, may be especially well suited to mindfulness approaches such as learning to observe physical sensations, thoughts, and emotions, as well as cultivating compassion towards themselves and others. The paper concludes with an exploration of unanswered and potential research questions regarding the future use of MBIs with adolescents with cancer, and potentially with teenagers with other chronic diseases. AD - National Cancer Institute, Center for Cancer Research, Bethesda, MD, 20892, USA. AN - 104091018. Language: English. Entry Date: 20140411. Revision Date: 20200708. Publication Type: journal article AU - Jones, Paul AU - Blunda, Megan AU - Biegel, Gina AU - Carlson, Linda E. AU - Biel, Matthew AU - Wiener, Lori DB - cin20 DO - 10.1002/pon.3251 DP - EBSCOhost IS - 9 KW - Anxiety -- Therapy Mindfulness -- Methods Neoplasms -- Psychosocial Factors Adaptation, Psychological Adolescence Anxiety -- Psychosocial Factors Quality of Life Treatment Outcomes N1 - review. Journal Subset: Biomedical; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. Special Interest: Oncologic Care; Psychiatry/Psychology. Grant Information: Z99 CA999999//Intramural NIH HHS/United States. NLM UID: 9214524. PMID: NLM23417883. PY - 2013 SN - 1057-9249 SP - 2148-2151 ST - Can mindfulness-based interventions help adolescents with cancer? T2 - Psycho-Oncology TI - Can mindfulness-based interventions help adolescents with cancer? UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104091018&site=ehost-live&scope=site VL - 22 ID - 518 ER - TY - JOUR AB - BACKGROUND AND METHODS: Questionnaires assessing knowledge of, attitudes toward, and behaviors relative to cervical cancer and its prevention were administered to 279 tenth-grade girls. RESULTS: Eighty-four percent had heard of cervical cancer, and 83% had heard of the Pap smear. Sexual intercourse with multiple partners and cigarette smoking were risk factors identified by 65% and 40% of these students, respectively. Forty-eight percent reported being sexually active. This group, compared with those not sexually active, was more likely to 1) identify the Pap test as a test involving a vaginal examination, 2) use tobacco products, and 3) be exposed to tobacco smoke. The most common barriers to obtaining a Pap test reported by those sexually active were embarrassment (64%), pain/discomfort (57%), fear of cancer (27%), fear of parents discovering sexual activity (25%), and cost (13%). CONCLUSIONS: Based on the information obtained in this study, the authors recommend changes in school health programs that target adolescent girls: 1) risk factors and behavior should receive more emphasis, and 2) the pelvic examination and Pap test should be described in sufficient detail to address the issues of embarrassment, pain, and discomfort. AD - Charleston Area Medical Center, Robert C Byrd Health Sciences Center of West Virginia University, 400 S Ruffner Rd., Charleston, WV 25314 AN - 107353743. Language: English. Entry Date: 19971201. Revision Date: 20150711. Publication Type: Journal Article AU - Jubelirer, S. J. AU - Blanton, M. F. AU - Blanton, P. D. AU - Zhang, J. AU - Foster, D. AU - Monk, J. AU - Kuhn, G. AU - Hanshew, D. DA - 1996 Winter DB - cin20 DP - EBSCOhost IS - 4 KW - Health Knowledge -- In Adolescence Attitude to Health -- In Adolescence Health Behavior -- In Adolescence Cervix Neoplasms -- Prevention and Control Cervical Smears West Virginia Risk Factors Students, High School Schools, Secondary Questionnaires Sexuality Smoking Validity Self Report Cervix Neoplasms -- Psychosocial Factors Age Factors Sex Factors Race Factors Chi Square Test P-Value Adolescence Female Human N1 - research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Health Promotion/Education; Peer Reviewed; USA. NLM UID: 8610343. PMID: NLM8989638. PY - 1996 SN - 0885-8195 SP - 230-237 ST - Assessment of knowledge, attitudes, and behaviors relative to cervical cancer and the Pap smear among adolescent girls in West Virginia T2 - Journal of Cancer Education TI - Assessment of knowledge, attitudes, and behaviors relative to cervical cancer and the Pap smear among adolescent girls in West Virginia UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=107353743&site=ehost-live&scope=site VL - 11 ID - 844 ER - TY - JOUR AB - Study Design: Prospective cohort study.Objective: To study symptoms, chronic disorders, and clinical findings in the low back, and work absenteeism, as predictors of hospitalization.Summary Of Background Data: Socioeconomic and lifestyle factors are associated with back-related hospitalization, but the significance in the working normal population of low back symptoms and clinical findings are not known.Methods: The cohort (n = 902) was drawn in 1973 from among employees in the metal industry (n = 2,653). The data were collected by questionnaire and a structured clinical assessment by a physiotherapist. Weight was measured. A sum score of local and radiating low back symptoms (frequency during the past year on a 4-point Likert scale) was categorized as no/yes and no/infrequent/frequent. Local and radiating symptoms were considered also separately. The data were linked with those from the Finnish Hospital Discharge Register during 1973 to 2000. Logistic regression and the Cox proportional hazard models were used.Results: As compared with persons without low back pain, those with frequent or radiating low back pain had an increased risk of hospitalization due to low back disorders (hazard rate ratio (HRR), 3.0; 95% confidence interval (CI), 1.4-6.5, and 3.7; 1.8-7.7, respectively) after adjustment for age, gender, and occupational class. Similarly, clinical findings (HRR, 2.4; 95% CI, 1.3-4.7), back-related absenteeism (HRR, 3.3; 95% CI, 1.6-6.7), and chronic low back disorders (HRR, 2.8; 95% CI, 1.5-5.4) predicted hospitalization. The associations persisted when further adjusted for smoking, body mass index, and distress symptoms at baseline.Conclusion: Frequent or radiating low back symptoms, chronic low back disorders, back-related work absenteeism, and having clinical findings in the low back predicted inpatient hospital care for low back disorders. AD - University of Jyväskylä, Jyväskylä, Finland AN - 106487345. Language: English. Entry Date: 20050715. Revision Date: 20200624. Publication Type: journal article AU - Kääriä, S. AU - Kaila-Kangas, L. AU - Kirjonen, J. AU - Riihimäki, H. AU - Luukkonen, R. AU - Leino-Arjas, P. AU - Kääriä, Sanna AU - Kaila-Kangas, Leena AU - Kirjonen, Juhani AU - Riihimäki, Hilkka AU - Luukkonen, Ritva AU - Leino-Arjas, Päivi DB - cin20 DO - 10.1097/01.brs.0000162283.95342.b5 DP - EBSCOhost IS - 10 KW - Low Back Pain -- Symptoms Occupational-Related Injuries -- Symptoms Chronic Pain Sick Leave Hospitalization Forecasting Prospective Studies Occupational Health Industry Blue Collar Workers Questionnaires Structured Interview Physical Therapists Body Weights and Measures Summated Rating Scaling Finland Cox Proportional Hazards Model Logistic Regression Confidence Intervals Odds Ratio White Collar Workers Descriptive Statistics Functional Assessment Pliability Lumbar Vertebrae Pain Measurement Muscle Spasticity Flexion Clinical Assessment Tools Physical Examination Body Mass Index -- Evaluation Smoking -- Evaluation Stress, Psychological Low Back Pain -- Psychosocial Factors Coefficient Alpha Data Analysis Software Adult Adolescence Middle Age Funding Source Human N1 - research; tables/charts. Journal Subset: Allied Health; Biomedical; Peer Reviewed; USA. Grant Information: Academy of Finland (project no. 70139) and Ministry of Education, Finland (188/722/2000). NLM UID: 7610646. PMID: NLM15897838. PY - 2005 SN - 0362-2436 SP - 1211-1218 ST - Low back pain, work absenteeism, chronic back disorders, and clinical findings in the low back as predictors of hospitalization due to low back disorders: a 28-year follow-up of industrial employees T2 - Spine (03622436) TI - Low back pain, work absenteeism, chronic back disorders, and clinical findings in the low back as predictors of hospitalization due to low back disorders: a 28-year follow-up of industrial employees UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106487345&site=ehost-live&scope=site VL - 30 ID - 752 ER - TY - JOUR AB - Migraine is a common disorder that starts at an early age and takes a variable pattern from intermittent to chronic headache with several exacerbations throughout a lifetime. Children and adolescents are significantly affected. If an acute headache is not aborted by outpatient migraine therapy, it often causes severe disability, preventing the child from attending school and social events. Treating the acute severe headache aggressively helps prevent prolonged disability as well as possible chronification. Multiple medications are available, mostly for the outpatient management of an attack and include the use of overthe- counter anti-inflammatory medications as well as prescribed medications in the triptan group. These therapies do sometime fail and the exacerbation can last from days to weeks. If the headache lasts 72 hours or longer it will fall in the category of status migrainosus. Status migrainosus is described as a severe disabling headache lasting 72 hours or more by the ICHD3 criteria. Disability is a major issue in children and adolescents and aggressive acute measures are to be taken to control it as soon as possible. Early aggressive intravenous therapy can be very effective in breaking the attack and allowing the child to be quickly back to normal functioning. This article reviews what is available for the treatment of pediatric primary headaches in the emergency room. AD - Division of Neurology, University of Cincinnati College of Medicine, Cincinnati OH, 45229‐3039, USA (M. Kabbouche) Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati OH, 45229‐3039, USA (M. Kabbouche). AN - 111280264. Language: English. Entry Date: 20151202. Revision Date: 20180702. Publication Type: Article AU - Kabbouche, Marielle DB - cin20 DO - 10.1111/head.12694 DP - EBSCOhost IS - 10 KW - Migraine -- Drug Therapy -- In Infancy and Childhood Treatment Outcomes Emergency Care Administration, Intravenous Dopamine Antagonists -- Administration and Dosage Dopamine Antagonists -- Pharmacodynamics Antipsychotic Agents -- Administration and Dosage Antipsychotic Agents -- Pharmacodynamics Antiinflammatory Agents, Non-Steroidal -- Administration and Dosage Antiinflammatory Agents, Non-Steroidal -- Pharmacodynamics Anticonvulsants -- Administration and Dosage Anticonvulsants -- Pharmacodynamics Dihydroergotamine -- Administration and Dosage Dihydroergotamine -- Pharmacodynamics Magnesium Sulfate -- Administration and Dosage Magnesium Sulfate -- Pharmacodynamics Dexamethasone -- Administration and Dosage Dexamethasone -- Pharmacodynamics Treatment Failure Child N1 - review; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 2985091R. PY - 2015 SN - 0017-8748 SP - 1365-1370 ST - Management of Pediatric Migraine Headache in the Emergency Room and Infusion Center T2 - Headache: The Journal of Head & Face Pain TI - Management of Pediatric Migraine Headache in the Emergency Room and Infusion Center UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=111280264&site=ehost-live&scope=site VL - 55 ID - 439 ER - TY - JOUR AB - Objective.- To assess the effectiveness of aggressive therapy of status migraine in children and adolescents. Background.- Inpatient management of pediatric status migraine and intractable headache is limited because of a lack of studies and guidelines. Adult treatment is often based on anecdotal experience, although a few controlled studies have been reported. Added to that is the discomfort of general pediatricians and neurologists in using available effective treatments in pediatric patients (such as dihydroergotamine: DHE). Methods.- Charts of all patients admitted to the neurology service, at Cincinnati Children's Hospital Medical Center-Department of Neurology, for inpatient treatment for intractable headache/status migraine over a 6-week period were reviewed. Demographics, evaluation, diagnosis, and treatment used were tabulated. Data on the effectiveness of the treatments provided were evaluated. Thirty-two total consecutive charts were retrospectively reviewed during that period. Results.- Upon discharge, 74.4% of the patients were headache-free. The mean severity of the pain upon discharge was 1.02 ± 2.22 (using the 0-10 pain scale). Conclusion.- From our review, DHE is very effective in treating and aborting an episode of status migraine and should be offered to children and adolescent patients who have failed their usual abortive therapy to prevent further severe disability that mainly affects their schooling and social activities. AD - Cincinnati Children's Hospital Medical Center, Department of Neurology, Cincinnati, OH 45229, USA. AN - 105614526. Language: English. Entry Date: 20090626. Revision Date: 20200708. Publication Type: Journal Article AU - Kabbouche, M. A. AU - Powers, S. W. AU - Segers, A. AU - LeCates, S. AU - Manning, P. AU - Biederman, S. AU - Vaughan, P. AU - Burdine, D. AU - Hershey, A. D. DB - cin20 DO - 10.1111/j.1526-4610.2008.01293.x DP - EBSCOhost IS - 1 KW - Child, Hospitalized Emergency Care -- Evaluation -- In Infancy and Childhood Ergotamine -- Therapeutic Use -- In Infancy and Childhood Migraine -- Drug Therapy -- In Infancy and Childhood Adolescence Child Descriptive Statistics Female Male Record Review Retrospective Design Human N1 - research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 2985091R. PMID: NLM19125879. PY - 2009 SN - 0017-8748 SP - 106-109 ST - Inpatient treatment of status migraine with dihydroergotamine in children and adolescents T2 - Headache: The Journal of Head & Face Pain TI - Inpatient treatment of status migraine with dihydroergotamine in children and adolescents UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105614526&site=ehost-live&scope=site VL - 49 ID - 670 ER - TY - JOUR AB - OBJECTIVE: To assess the long-term effectiveness and outcome of multidisciplinary treatment of childhood headaches 1, 2, and 5 years after initial treatment. BACKGROUND: Headaches are a common problem for children and adolescents and for many patients continue into adulthood. Outcome research for pediatric migraine headaches is limited, thus restricting knowledge of the effectiveness of long-term management and outcome. METHODS: Headache characteristics were assessed at the initial visit and were reevaluated 1, 2, and 5 years later in independent sub-groups of consecutive patients. These characteristics included headache frequency, severity, average duration, school absences, and overall perceived response to treatment. RESULTS: At 1 year, 96 patients were evaluated (mean age = 11.0 +/- 3.4, 59% females), 69 patients at 2 years (mean age = 10.6 +/- 3.4, 48% females), and 32 at 5 years (mean age = 10.5 +/- 3.9, 66% females). The headaches were reported as better in 94% at 1 year, 85% at 2 years, and 94% at 5 years. The initial frequency was at 13.4 +/- 10.8 headaches per month, 4.9 +/- 7.0 at 1 year (P < .001), 4.7 +/- 7.6 at 2 years (P < .001), and 4.5 +/- 7.5 at 5 years (P < .001). The severity decreased from 6.8 +/- 1.8 to 5.1 +/- 2.3 at 1 year (P < .001), to 5.0 +/- 2.4 at 2 years (P < .001), and to 4.6 +/- 2.5 at 5 years (P < .01). The school days missed per month showed a marked decrease from 4.5 +/- 9.5 at initial visit to 1.55 +/- 2.8 at 5 years (P < .001). Patients that were only seen at their initial visit and did not choose to return for follow-up had less frequent and shorter duration headaches on initial visit when compared with the rest of the sample and continued to be doing well at the 1-, 2-, and 5-year assessments. CONCLUSIONS: Multidisciplinary treatment was found to be effective for children and adolescents with improvement of multiple outcome variants of pediatric migraine care, including frequency, severity, and school days missed. Patients who did not return to follow-up evaluation were more likely to have less frequent and shorter duration headaches at initial presentation. Regular follow-up care is needed for those children with more severe initial headache presentation. AD - Headache Center, Division of Neurology, Cincinnati Children's Hospital Medical Center, MCL #2015, 3333 Burnet Avenue, Cincinnati, OH AN - 106394535. Language: English. Entry Date: 20070101. Revision Date: 20200708. Publication Type: Journal Article AU - Kabbouche, M. A. AU - Powers, S. W. AU - Vockell, A. B. AU - LeCates, S. L. AU - Ellinor, P. L. AU - Segers, A. AU - Manning, P. AU - Burdine, D. AU - Hershey, A. D. DB - cin20 DO - 10.1111/j.1526-4610.2005.00261.x DP - EBSCOhost IS - 10 KW - Migraine -- Therapy -- In Infancy and Childhood Multidisciplinary Care Team Pediatric Care -- Evaluation Treatment Outcomes Absenteeism Adolescence Child Child, Preschool Descriptive Statistics Female Male Migraine -- Education Outcomes Research P-Value Patient Education Questionnaires Retrospective Design Severity of Illness Human N1 - research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 2985091R. PMID: NLM16324161. PY - 2005 SN - 0017-8748 SP - 1298-1303 ST - Outcome of a multidisciplinary approach to pediatric migraine at 1, 2, and 5 years T2 - Headache: The Journal of Head & Face Pain TI - Outcome of a multidisciplinary approach to pediatric migraine at 1, 2, and 5 years UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106394535&site=ehost-live&scope=site VL - 45 ID - 741 ER - TY - JOUR AD - PhD, Pain Treatment Service, Children's Hospital Boston, 333 Longwood Avenue, Boston, MA 02115, USA. karen.kaczynski@childrens.harvard.edu. AN - 107903407. Language: English. Entry Date: 20140516. Revision Date: 20200708. Publication Type: Journal Article AU - Kaczynski, Karen J. AU - Claar, Robyn Lewis AU - Lebel, Alyssa A. DB - cin20 DO - 10.1093/jpepsy/jss120 DP - EBSCOhost IS - 4 KW - Depression -- Psychosocial Factors Migraine -- Psychosocial Factors Parenting Tension Headache -- Psychosocial Factors Achievement Adolescence Adult Anxiety -- Epidemiology Anxiety -- Physiopathology Anxiety -- Psychosocial Factors Child Comorbidity Depression -- Epidemiology Depression -- Physiopathology Female Human Male Migraine -- Epidemiology Migraine -- Physiopathology Pain Measurement Retrospective Design Schools Tension Headache -- Epidemiology Tension Headache -- Physiopathology N1 - research. Journal Subset: Biomedical; Peer Reviewed; USA. Special Interest: Pediatric Care; Psychiatry/Psychology. NLM UID: 7801773. PMID: NLM23248346. PY - 2013 SN - 0146-8693 SP - 351-364 ST - Relations between pain characteristics, child and parent variables, and school functioning in adolescents with chronic headache: a comparison of tension-type headache and migraine T2 - Journal of Pediatric Psychology TI - Relations between pain characteristics, child and parent variables, and school functioning in adolescents with chronic headache: a comparison of tension-type headache and migraine UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=107903407&site=ehost-live&scope=site VL - 38 ID - 527 ER - TY - JOUR AB - Purpose: Minimal research has been conducted to understand how fatigue influences quality of life (QOL) among adolescents living with HIV. The purpose of the study was to examine the relationship between fatigue, sleep disturbance, depression, anxiety, pain and QOL among adolescents receiving antiretroviral therapy (ART).Methods: Using a cross-sectional survey design, we studied 134 South African adolescents receiving an ART at community clinics.Results: Participants in general reported low levels of fatigue, insomnia, distress and pain and non-problematic levels of QOL. In the regression model, the linear combination of these variables explained 49% of the variance in QOL, a large effect size. Insomnia, anxiety, and depression significantly predicted QOL but surprisingly fatigue and pain did not.Conclusions: Many members of the sample experienced non-clinical levels of sleep disturbance, fatigue and psychosocial distress. Similarly, QOL was within the normal range. These findings are surprising as the commonly held assumption is that adolescents living with HIV, especially those of poorer socio-economic backgrounds, would experience lower QOL than the norm. Even though scores on the instruments measuring these variables fell in the non-clinical range, they were still robustly predictive of poor QOL. Future research may address the relationship between self-reported adherence and QOL, possibly by examining the role of viral load as a mediating variable. Further research may also focus on non-adherent adolescents to understand the ways in which fatigue and other factors such as school functioning and social interaction influence QOL. AD - Department of Psychology, Stellenbosch University, Private Bag X1, Matieland, Stellenbosch, South Africa Department of Psychology, University of Bath, BA2 7AY, Bath, UK AN - 134208192. Language: English. Entry Date: In Process. Revision Date: 20210111. Publication Type: journal article. Journal Subset: Allied Health AU - Kagee, A. AU - Coetzee, B. AU - Toit, S. Du AU - Loades, M. E. DB - cin20 DO - 10.1007/s11136-018-2010-5 DP - EBSCOhost IS - 1 KW - Viral Load HIV Infections -- Psychosocial Factors Anti-Retroviral Agents -- Adverse Effects Quality of Life -- Psychosocial Factors South Africa Young Adult Male HIV Infections -- Drug Therapy Female Adolescence Adult Cross Sectional Studies Ferrans and Powers Quality of Life Index Psychosocial Adjustment to Illness Scale Questionnaires Scales Social Readjustment Rating Scale Ways of Coping Questionnaire N1 - Peer Reviewed; Public Health; USA. Instrumentation: Psychosocial Adjustment to Illness Scale (PAIS); Clinical Decision Making in Nursing Scale (CDMNS) (Jenkins); Ways of Coping Questionnaire (WCQ) (Folkman et al); General Health Questionnaire (GHQ); Longitudinal Interval Follow-Up Evaluation (LIFE); Ferrans and Powers Quality of Life Index; Social Readjustment Rating Scale (SRRS) (Holmes and Rahe). Grant Information: DRF-2016-09-021//Department of Health/United Kingdom. NLM UID: 9210257. PMID: NLM30244360. PY - 2019 SN - 0962-9343 SP - 57-65 ST - Psychosocial predictors of quality of life among South Africa adolescents receiving antiretroviral therapy T2 - Quality of Life Research TI - Psychosocial predictors of quality of life among South Africa adolescents receiving antiretroviral therapy UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=134208192&site=ehost-live&scope=site VL - 28 ID - 273 ER - TY - JOUR AB - Objective: To examine pain self-efficacy and pain acceptance in relation to functioning in pediatric patients with chronic headache.Methods: Participants were 209 youth aged 8-17 years who presented for a multidisciplinary pediatric headache clinic evaluation. They completed measures of pain self-efficacy and pain acceptance and a standard battery of clinical measures including indicators of emotional functioning.Results: Pain self-efficacy and acceptance were associated with less disability, better school functioning, and fewer depressive symptoms. While taking into account several demographic and pain-related variables, pain self-efficacy had a greater association with less functional disability, while pain acceptance had a greater association with less depressive symptoms and better school functioning.Conclusions: These findings indicate that both resilience processes can serve to positively interact with functioning and symptoms of depression. Ultimately, this study suggests that higher levels of pain self-efficacy and pain acceptance in an individual experiencing pain are associated with more positive outcomes. AD - Harvard College, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children's Hospital Division of Pain Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children's Hospital Department of Psychiatry, Harvard Medical School P.A.I.N. Group, Boston Children's Hospital, Center for Pain and the Brain, Harvard Medical School Division of Pain Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children's Hospital, Department of Psychiatry, Harvard Medical School, and P.A.I.N. Group, Boston Children's Hospital, Center for Pain and the Brain, Harvard Medical School AN - 109970646. Language: English. Entry Date: 20160526. Revision Date: 20190619. Publication Type: journal article AU - Kalapurakkel, Sreeja AU - Carpino, Elizabeth A. AU - Lebel, Alyssa AU - Simons, Laura E. AU - A Carpino, Elizabeth AU - E Simons, Laura DB - cin20 DO - 10.1093/jpepsy/jsu091 DP - EBSCOhost IS - 9 KW - Hardiness Headache -- Psychosocial Factors Self-Efficacy Pain -- Psychosocial Factors Male Disabled Child Pain Measurement Female Adolescence Depression -- Psychosocial Factors Emotions Human N1 - research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 7801773. PMID: NLM25324532. PY - 2015 SN - 0146-8693 SP - 926-933 ST - "Pain Can't Stop Me": Examining Pain Self-Efficacy and Acceptance as Resilience Processes Among Youth With Chronic Headache T2 - Journal of Pediatric Psychology TI - "Pain Can't Stop Me": Examining Pain Self-Efficacy and Acceptance as Resilience Processes Among Youth With Chronic Headache UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=109970646&site=ehost-live&scope=site VL - 40 ID - 445 ER - TY - JOUR AB - Introduction: Musculoskeletal (MSK) pain in children and adolescents is responsible for substantial personal impacts and societal costs, but it has not been intensively or systematically researched. This means our understanding of these conditions is limited, and healthcare professionals have little empirical evidence to underpin their clinical practice. In this article we summarise the state of the evidence concerning MSK pain in children and adolescents, and offer suggestions for future research. Results: Rates of self-reported MSK pain in adolescents are similar to those in adult populations and they are typically higher in teenage girls than boys. Epidemiological research has identified conditions such as back and neck pain as major causes of disability in adolescents, and in up to a quarter of cases there are impacts on school or physical activities. A range of physical, psychological and social factors have been shown to be associated with MSK pain report, but the strength and direction of these relationships are unclear. There are few validated instruments available to quantify the nature and severity of MSK pain in children, but some show promise. Several national surveys have shown that adolescents with MSK pain commonly seek care and use medications for their condition. Some studies have revealed a link between MSK pain in adolescents and chronic pain in adults. Conclusion: Musculoskeletal pain conditions are often recurrent in nature, occurring throughout the life-course. Attempts to understand these conditions at a time close to their initial onset may offer a better chance of developing effective prevention and treatment strategies. AD - George Institute, University of Sydney, Australia Institute of Public Health, University of Heidelberg, Heidelberg, Germany Department of Sport Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark Arthritis Research UK Primary Care Centre, Institute for Primary Care and Health Sciences, Keele University, Keele, UK Hunter Medical Research Institute, School of Medicine and Public Health, University of Newcastle, Newcastle, Australia Hunter New England Population Health, Hunter New England Local Health District, Australia AN - 116867789. Language: English. Entry Date: 20160722. Revision Date: 20160725. Publication Type: Article AU - Kamper, Steve J. AU - Henschke, Nicholas AU - Hestbaek, Lise AU - Dunn, Kate M. AU - Williams, Christopher M. DB - cin20 DO - 10.1590/bjpt-rbf.2014.0149 DP - EBSCOhost IS - 3 KW - Pain -- In Infancy and Childhood Musculoskeletal Diseases -- In Infancy and Childhood Pain -- In Adolescence Musculoskeletal Diseases -- In Adolescence Incidence Prevalence Pain -- Risk Factors -- In Adolescence Prognosis Health Resource Utilization Pain Measurement Pain -- Epidemiology -- In Infancy and Childhood Pain -- Epidemiology -- In Adolescence Child Adolescence N1 - tables/charts. Journal Subset: Allied Health; Blind Peer Reviewed; Double Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Mexico & Central/South America; Peer Reviewed. Special Interest: Pain and Pain Management; Pediatric Care. NLM UID: 101186153. PY - 2016 SN - 1413-3555 SP - 275-284 ST - Musculoskeletal pain in children and adolescents T2 - Brazilian Journal of Physical Therapy TI - Musculoskeletal pain in children and adolescents UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=116867789&site=ehost-live&scope=site VL - 20 ID - 408 ER - TY - JOUR AB - Objective: Chronic pain is associated with school difficulties; however, there is limited published evidence on the cognitive or neuropsychological functioning of youth with chronic pain.Method: When beginning intensive interdisciplinary pain treatment, 94 youth (age = 10-18) with chronic pain completed neuropsychological assessment (e.g., intelligence, academic skills, learning and recall, and attention) and clinical questionnaires (e.g., pain and physical and psychological functioning). We compared neuropsychological scores with test norms and with clinical questionnaires.Results: Youth with chronic pain had higher verbal comprehension and full scale IQ scores than expected, below-average nondominant hand dexterity, and difficulty with visual recall. Self-reported difficulties with executive functioning were associated with small-to-moderate difficulties with objectively measured attention. Performance on neuropsychological measures was generally not associated with pain, impairment, anxiety, or depression, though catastrophizing was negatively correlated with perceptual reasoning. An expected number of these youth had learning disorders (14%); however, more than expected had an autism spectrum disorder (9%) or attention deficit hyperactivity disorder (18%), and nearly a quarter demonstrated characteristics of nonverbal learning disability (22%).Conclusions: Some of these cognitive findings may be a consequence of chronic pain, and others may reflect subtle neurodevelopmental differences that may predate or be comorbid with pain. Regardless of etiology, with more than half the current sample experiencing some type of learning challenge, often undiagnosed, pediatric psychologists evaluating youth with chronic pain may wish to screen for comorbid learning difficulties. AD - Children's Mercy Kansas City School of Medicine, University of Missouri Kansas City Children's Mercy Kansas City School of Medicine, University of Missouri Kansas City AN - 131245153. Language: English. Entry Date: In Process. Revision Date: 20191119. Publication Type: journal article. Journal Subset: Biomedical AU - Kapalu, Christina M. Low AU - Hall, John J. AU - Wallace, Dustin P. AU - Low Kapalu, Christina M. DB - cin20 DO - 10.1093/jpepsy/jsy034 DP - EBSCOhost IS - 8 KW - Cognition Disorders -- Complications Pain -- Therapy Cognition Disorders -- Psychosocial Factors Chronic Pain -- Complications Chronic Pain -- Therapy Cognition Disorders -- Physiopathology Self Report Neuropsychological Tests -- Statistics and Numerical Data Male Female Adolescence Child Chronic Pain -- Psychosocial Factors Scales N1 - Peer Reviewed; USA. Instrumentation: Learning and Study Strategies Inventory (LASSI); Screen for Caregiver Burden (SCB); Clinical Decision Making in Nursing Scale (CDMNS) (Jenkins). NLM UID: 7801773. PMID: NLM29846679. PY - 2018 SN - 0146-8693 SP - 870-881 ST - Neuropsychological Functioning of Youth Receiving Intensive Interdisciplinary Pain Treatment T2 - Journal of Pediatric Psychology TI - Neuropsychological Functioning of Youth Receiving Intensive Interdisciplinary Pain Treatment UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=131245153&site=ehost-live&scope=site VL - 43 ID - 292 ER - TY - JOUR AB - It has been proposed that goal pursuit plays a role in the development of chronic pain disorders. On the basis of (affective) motivational theories, it was hypothesized that both long-term achievement goals and short-term hedonic goals would be related to increased levels of pain and disability, particularly in patients with high negative affect. Participants with musculoskeletal pain complaints (N=299) completed a battery of questionnaires including a novel goal pursuit questionnaire (GPQ) measuring the extent to which participants preferred hedonic goals (mood-management or pain-avoidance goals) over achievement goals in various situations. Explorative factor analysis of the GPQ resulted in a reliable pain-avoidance (α=.88) and mood-management subscale (α=.76). A nonlinear, U-shaped relationship was found among the pain-avoidance scale (but not the mood-management scale) and pain and disability. This indicated that participants who strongly endorsed either achievement or pain-avoidance goals also reported higher pain and disability levels while controlling for biographical variables and pain catastrophizing. For pain but not disability, these relationships were only found among patients with high negative affect. For disability, goal pursuit and negative affect were independently related to disability. These findings provide support for the validity of an affective-motivational approach to chronic pain, suggesting that the experience of pain and the interference of pain on daily life activities depends on goal pursuit and negative affect. Interventions aimed at improving disability in chronic pain should address both patient's goal pursuit and negative affect. An affective-motivational approach to chronic pain indicates that achievement and pain-avoidance goals are associated with pain severity and disability, particularly in patients with high negative affect. AD - Department Clinical Psychological Science, Research Group Behavioral Medicine, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands Department of Psychology, Research Group Health Psychology, University of Leuven, Tiensestraat 102, 3000 Leuven, Belgium Department Clinical Psychological Science, Research Group Behavioral Medicine, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands. AN - 104904900. Language: English. Entry Date: 20111007. Revision Date: 20210115. Publication Type: journal article AU - Karsdorp, P. A. AU - Vlaeyen, J. W. AU - Karsdorp, Petra A. AU - Vlaeyen, Johan W. S. DB - cin20 DO - 10.1016/j.pain.2011.02.018 DP - EBSCOhost IS - 6 KW - Achievement Goals and Objectives Low Back Pain -- Psychosocial Factors Pain -- Pathology Pain -- Psychosocial Factors Upper Extremity -- Physiopathology Activities of Daily Living Adolescence Adult Disability Evaluation Factor Analysis Fear Female Male Middle Age Pain Measurement Questionnaires Regression Reproducibility of Results Young Adult N1 - research. Journal Subset: Biomedical; Continental Europe; Europe; Peer Reviewed. NLM UID: 7508686. PMID: NLM21392886. PY - 2011 SN - 0304-3959 SP - 1382-1390 ST - Goals matter: Both achievement and pain-avoidance goals are associated with pain severity and disability in patients with low back and upper extremity pain T2 - PAIN TI - Goals matter: Both achievement and pain-avoidance goals are associated with pain severity and disability in patients with low back and upper extremity pain UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104904900&site=ehost-live&scope=site VL - 152 ID - 580 ER - TY - JOUR AB - Objective: To equip clinicians with recommendations specific to concerns related to the novel coronavirus disease 2019 (COVID‐19), which impact the physical, emotional, and social health of youth with headache disorders. Background: COVID‐19 has affected societies on a global scale including children and youth with chronic headache disorders. Many concerns are predicted to arise in the 2020–2021 school year, whether classes are conducted in‐person or virtually. Methods: Clinical impressions were combined with a review of the literature, although limited due to the recent nature of this issue. Results: We describe recommendations to support caregivers and youth as they face changes expected with the return to school in the fall of 2020. Conclusion: Although there are significant concerns for caregivers and youth with migraine given the context of changes related to the pandemic, there are many recommendations that can help minimize exacerbations of the physical, emotional, and social health of youth with chronic migraine. AD - Division of Neurology, Children's Hospital of Philadelphia, Philadelphia PA,, USA Ferkauf Graduate School of Psychology, Yeshiva University, New York NY,, USA UCSF Benioff Children's Hospital, University of California, San Francisco CA,, USA Department of Neurology, Mayo Clinic, Scottsdale AZ,, USA Penn Therapy & Fitness, University City, Philadelphia PA,, USA Department of Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia PA,, USA Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia PA,, USA Department of Neurology, University of Alabama at Birmingham, School of Medicine, Birmingham AL,, USA Department of Psychiatry, University of Colorado Anschutz Medical Campus and Children's Hospital Colorado, Aurora CO,, USA Department of Pediatrics, University of Colorado Anschutz Medical Campus and Children's Hospital Colorado, Aurora CO,, USA Division of Child Neurology, Children's Mercy Hospital, University of Missouri‐Kansas City School of Medicine, Kansas City MO,, USA AN - 148337301. Language: English. Entry Date: 20210130. Revision Date: 20210130. Publication Type: Article AU - Karvounides, Dina AU - Marzouk, Maya AU - Ross, Alexandra C. AU - VanderPluym, Juliana H. AU - Pettet, Christina AU - Ladak, Ali AU - Ziplow, Jason AU - Patterson Gentile, Carlyn AU - Turner, Scott AU - Anto, Marissa AU - Barmherzig, Rebecca AU - Chadehumbe, Madeline AU - Kalkbrenner, Jocelyn AU - Malavolta, Carrie P. AU - Clementi, Michelle A. AU - Gerson, Trevor AU - Szperka, Christina L. DB - cin20 DO - 10.1111/head.14038 DP - EBSCOhost IS - 1 KW - COVID-19 -- Psychosocial Factors Headache -- In Infancy and Childhood School Health School Re-Entry Caregivers Child Adolescence Chronic Disease Migraine N1 - pictorial; review; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 2985091R. PY - 2021 SN - 0017-8748 SP - 190-201 ST - The intersection of COVID‐19, school, and headaches: Problems and solutions T2 - Headache: The Journal of Head & Face Pain TI - The intersection of COVID‐19, school, and headaches: Problems and solutions UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=148337301&site=ehost-live&scope=site VL - 61 ID - 155 ER - TY - JOUR AB - Objective: To describe school absences in adolescents with Juvenile Primary Fibromyalgia Syndrome (JPFS) and examine the relationship between school absenteeism, pain, psychiatric symptoms, and maternal pain history.Methods: Adolescents with JPFS (N = 102; mean age 14.96 years) completed measures of pain and depressive symptoms, and completed a psychiatric interview. Parents provided information about the adolescents' school absences, type of schooling, and parental pain history. School attendance reports were obtained directly from schools.Results: Over 12% of adolescents with JPFS were homeschooled. Those enrolled in regular school missed 2.9 days per month on average, with one-third of participants missing more than 3 days per month. Pain and maternal pain history were not related to school absenteeism. However, depressive symptoms were significantly associated with school absences.Conclusion: Many adolescents with JPFS experience difficulties with regular school attendance. Long-term risks associated with school absenteeism and the importance of addressing psychological factors are discussed. AD - Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA AN - 104924321. Language: English. Entry Date: 20110121. Revision Date: 20161116. Publication Type: journal article. Journal Subset: Biomedical AU - Kashikar-Zuck, S. AU - Johnston, M. AU - Ting, T. V. AU - Graham, B. T. AU - Lynch-Jordan, A. M. AU - Verkamp, E. AU - Passo, M. AU - Schikler, K. N. AU - Hashkes, P. J. AU - Spalding, S. AU - Banez, G. AU - Richards, M. M. AU - Powers, S. W. AU - Arnold, L. M. AU - Lovell, D. AU - Kashikar-Zuck, Susmita AU - Johnston, Megan AU - Ting, Tracy V. AU - Graham, Brent T. AU - Lynch-Jordan, Anne M. DB - cin20 DO - 10.1093/jpepsy/jsq020 DP - EBSCOhost IS - 9 KW - Absenteeism Depression -- Psychosocial Factors Fibromyalgia -- Psychosocial Factors Pain -- Psychosocial Factors Adolescence Child Depression -- Complications Female Fibromyalgia -- Complications Male Pain -- Complications Pain Measurement Schools N1 - Peer Reviewed; USA. Grant Information: R01 AR050028/AR/NIAMS NIH HHS/United States. NLM UID: 7801773. PMID: NLM20360017. PY - 2010 SN - 0146-8693 SP - 996-1004 ST - Relationship between school absenteeism and depressive symptoms among adolescents with juvenile fibromyalgia T2 - Journal of Pediatric Psychology TI - Relationship between school absenteeism and depressive symptoms among adolescents with juvenile fibromyalgia UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104924321&site=ehost-live&scope=site VL - 35 ID - 611 ER - TY - JOUR AB - This study describes pain characteristics, coping, depression, and functional disability in children with juvenile primary fibromyalgia syndrome (JPFS) and compares them with a group of children with nonmalignant chronic back pain (CBP). Subjects were 18 female subjects (9 to 19 years of age) diagnosed with JPFS and 18 matched control subjects with CBP. Visual Analog Pain Rating Scales, the Pain Coping Questionnaire, the Children's Depression Inventory, and Functional Disability Inventory were administered. Results indicated that both JPFS and CBP groups reported significant disruption in functional abilities and school attendance as a result of chronic pain. Both groups reported mildly elevated symptoms of depression overall, but there was a subgroup of JPFS subjects who reported severe levels of depression. The JPFS group had suffered from pain for significantly longer than the CBP group before being referred for specialty care. However, pain duration was not significantly related to depression, functional disability, or pain coping efficacy. The levels of functional disability were similar in both groups, but the JPFS group reported somewhat more school absences. The longer time to receive specialty care and identification of a subgroup of depressed subjects at risk for long-term psychosocial consequences are of particular concern in JPFS. AD - Division of Psychology, Children's Hospital Medical Center and Department of Pediatrics, University of Cincinnati College of Medicine, 45229, USA Assistant Professor of Pediatrics, Psychology Division, Children's Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229; kasq6s@chmcc.org AN - 106818490. Language: English. Entry Date: 20030328. Revision Date: 20191111. Publication Type: journal article AU - Kashikar-Zuck, S. AU - Vaught, M. H. AU - Goldschneider, K. R. AU - Graham, T. B. AU - Miller, J. C. AU - Kashikar-Zuck, Susmita AU - Vaught, Michelle H. AU - Goldschneider, Kenneth R. AU - Graham, Thomas B. AU - Miller, Jonathan C. DB - cin20 DP - EBSCOhost IS - 5 KW - Fibromyalgia -- Psychosocial Factors -- In Infancy and Childhood Fibromyalgia -- Psychosocial Factors -- In Adolescence Chronic Pain -- Psychosocial Factors -- In Infancy and Childhood Chronic Pain -- Psychosocial Factors -- In Adolescence Pain Measurement Clinical Assessment Tools Coping -- In Infancy and Childhood Coping -- In Adolescence Depression -- In Infancy and Childhood Psychological Tests Depression -- In Adolescence Absenteeism Comparative Studies Descriptive Statistics Pearson's Correlation Coefficient Chi Square Test One-Way Analysis of Variance Analysis of Covariance T-Tests Child Adolescence Female Funding Source Human N1 - research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. Instrumentation: Children's Depression Inventory (CDI) (Kovacs and Beck); Functional Disability Inventory (FDI); Pain Coping Questionnaire (PCQ). Grant Information: Supported in part by grants from the Children's Hospital Research Foundation, Children's Hospital, Cincinnati and NIH Grant #1P60AR47784-01. NLM UID: 100898657. PMID: NLM14622745. PY - 2002 SN - 1526-5900 SP - 412-419 ST - Depression, coping, and functional disability in juvenile primary fibromyalgia syndrome T2 - Journal of Pain TI - Depression, coping, and functional disability in juvenile primary fibromyalgia syndrome UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106818490&site=ehost-live&scope=site VL - 3 ID - 793 ER - TY - JOUR AB - Summary: Chronic pain in children is associated with significant negative impact on social, emotional, and school functioning. Previous studies on the impact of pain on children's functioning have primarily used mixed samples of pain conditions or single pain conditions (eg, headache and abdominal pain) with relatively small sample sizes. As a result, the similarities and differences in the impact of pain in subgroups of children with chronic pain have not been closely examined.Objective: To compare pain characteristics, quality of life, and emotional functioning among youth with pediatric chronic migraine (CM) and juvenile fibromyalgia (JFM).Methods: We combined data obtained during screening of patients for 2 relatively large intervention studies of youth (age range, 10 to 18 y) with CM (N=153) and JFM (N=151). Measures of pain intensity, quality of life (Pediatric Quality of Life; PedsQL, child and parent-proxy), depressive symptoms (Children's Depression Inventory), and anxiety symptoms (Adolescent Symptom Inventory-4-Anxiety subscale) were completed by youth and their parent. A multivariate analysis of covariance controlling for effects of age and sex was performed to examine differences in quality of life and emotional functioning between the CM and JFM groups.Results: Youth with JFM had significantly higher anxiety and depressive symptoms, and lower quality of life in all domains. Among children with CM, overall functioning was higher but school functioning was a specific area of concern.Discussion: Results indicate important differences in subgroups of pediatric pain patients and point to the need for more intensive multidisciplinary intervention for JFM patients. AD - Divisions of *Behavioral Medicine and Clinical Psychology tNeurology §Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center tDepartment of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, OH. AN - 107917244. Language: English. Entry Date: 20140711. Revision Date: 20161117. Publication Type: journal article AU - Kashikar-Zuck, Susmita AU - Zafar, Marium AU - Barnett, Kimberly A. AU - Aylward, Brandon S. AU - Strotman, Daniel AU - Slater, Shalonda K. AU - Allen, Janelle R. AU - Lecates, Susan L. AU - Kabbouche, Marielle A. AU - Ting, Tracy V. AU - Hershey, Andrew D. AU - Powers, Scott W. DB - cin20 DO - 10.1097/AJP.0b013e3182850544 DP - EBSCOhost IS - 12 KW - Adaptation, Psychological Chronic Pain -- Psychosocial Factors Emotions Fibromyalgia -- Psychosocial Factors Migraine -- Psychosocial Factors Quality of Life -- Psychosocial Factors Adolescence Child Depression -- Psychosocial Factors Female Human Male Pain Measurement N1 - research. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Pain and Pain Management. Grant Information: UL1 TR000077/TR/NCATS NIH HHS/United States. NLM UID: 8507389. PMID: NLM23446072. PY - 2013 SN - 0749-8047 SP - 1066-1072 ST - Quality of life and emotional functioning in youth with chronic migraine and juvenile fibromyalgia T2 - Clinical Journal of Pain TI - Quality of life and emotional functioning in youth with chronic migraine and juvenile fibromyalgia UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=107917244&site=ehost-live&scope=site VL - 29 ID - 504 ER - TY - JOUR AB - Purpose. A hospital-based outreach program was initiated to screen minority children in medically underserved areas of New York City for musculoskeletal diseases. We examine the number of such diseases in this population, and evaluate the program's success to facilitate referral and follow-up of children with referral conditions. Methods. Screenings were conducted at schools and day-care centers. Children requiring further evaluation were referred to the sponsoring hospital, a major referral center for musculoskeletal diseases. Bilingual educational strategies, transportation reimbursement, and coverage for uninsured children were used to foster participation and increase follow-up. Results. A total of 2,523 children were screened, 168 (6.7%) of whom were referred for one of 45 different musculoskeletal disorders, including scoliosis and back problems, foot problems, in- and out-toeing, knee or hip pain, and problems of joint range of motion. Sixty-seven percent of those referred had a follow-up medical consultation. Conclusions. A substantial proportion of urban minority children have previously undiagnosed musculoskeletal disorders that, if left untreated, have the potential to lead to significant disabiltiy in later life. Targeted screening programs can be effective in identifying such disorders, and providing an opportunity for early diagnosis, treatment, and education. AD - Dept Physical Educ, Lantz Bldg, Eastern Illinois Univ, Charleston, IL 61920 AN - 107475884. Language: English. Entry Date: 19931201. Revision Date: 20200701. Publication Type: Journal Article AU - Kasper, M. J. AU - Robbins, L. AU - Root, L. AU - Peterson, M. G. E. AU - Allegrante, J. P. DB - cin20 DO - 10.1002/art.1790060304 DP - EBSCOhost IS - 3 KW - Musculoskeletal Diseases -- Diagnosis -- In Infancy and Childhood Health Screening -- In Infancy and Childhood Public Health Program Evaluation Referral and Consultation Child, Preschool Child Male Female N1 - tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 8809082. PMID: NLM8130288. PY - 1993 SN - 0893-7524 SP - 126-133 ST - A musculoskeletal outreach screening, treatment, and education program for urban minority children T2 - Arthritis Care & Research (08937524) TI - A musculoskeletal outreach screening, treatment, and education program for urban minority children UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=107475884&site=ehost-live&scope=site VL - 6 ID - 855 ER - TY - JOUR AB - Male circumcision (MC), an effective HIV prevention tool, has been added to Zimbabwe's Ministry of Health and Child Care HIV/AIDS Prevention Program. A Phase I safety trial of a nonsurgical male circumcision device was conducted and extensive psychosocial variables were assessed. Fifty-three men (18 and older) were recruited for the device procedure; 13 follow-up clinical visits were completed. Interviews conducted three times (before the procedure, at 2 weeks and 90 days post-procedure) assessed: Satisfaction; expectations; actual experience; activities of daily living; sexual behavior; and HIV risk perception. Using the Integrated Behavioral Model, attitudes towards MC, sex, and condoms, and sources of social influence and support were also assessed. Men (mean age 32.5, range 18-50; mean years of education = 13.6; 55% employed) were satisfied with device circumcision results. Men understand that MC is only partially protective against HIV acquisition. Most (94.7%) agreed that they will continue to use condoms to protect themselves from HIV. Pain ratings were surprisingly negative for a procedure billed as painless. Men talked to many social networks members about their MC experience; post-procedure (mean of 14 individuals). Minimal impact on activities of daily living and absenteeism indicate possible cost savings of device circumcisions. Spontaneous erections occurred frequently post-procedure. The results had important implications for changes in the pre-procedure clinical counseling protocol. Clear-cut counseling to manage pain and erection expectations should result in improved psychosocial outcomes in future roll-out of device circumcisions. Men's expectations must be managed through evidence-based counseling, as they share their experiences broadly among their social networks. AD - Department of Family and Child Nursing, School of Nursing, Seattle, Washington. Center for Studies in Demography and Ecology, University of Washington, Seattle, Washington. Department of Health Services, University of Washington, Seattle, Washington. Department of Neurobiology, University of Washington, Seattle, Washington. Department of Community Medicine, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe. AIDS, TB, and STI Unit, Ministry of Health and Child Care, Harare, Zimbabwe. AN - 112191950. Language: English. Entry Date: 20160112. Revision Date: 20190306. Publication Type: Article AU - Kasprzyk, Danuta AU - Montaño, Daniel E. AU - Hamilton, Deven T. AU - Down, Kayla L. AU - Marrett, Karl D. AU - Tshimanga, Mufuta AU - Xaba, Sinokuthemba AU - Mugurungi, Owen DB - cin20 DO - 10.1089/apc.2015.0111 DP - EBSCOhost IS - 1 KW - Circumcision -- Psychosocial Factors -- Zimbabwe HIV Infections -- Prevention and Control Noninvasive Procedures Zimbabwe Human Male Adult Middle Age Interviews Summated Rating Scaling Scales Descriptive Statistics Data Analysis Software Repeated Measures T-Tests Prospective Studies Coefficient Alpha Post Hoc Analysis Patient Satisfaction Funding Source N1 - research; tables/charts. Journal Subset: Biomedical; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Men's Health; Public Health. Instrumentation: Activities of Daily Living (ADL) Scale. Grant Information: This work was funded by the Battelle Memorial Institute and the Internal Research and Development Funds/UNFPA Zimbabwe Office.. NLM UID: 9607225. PY - 2016 SN - 1087-2914 SP - 25-33 ST - Psychosocial Results from a Phase I Trial of a Nonsurgical Circumcision Device for Adult Men in Zimbabwe T2 - AIDS Patient Care & STDs TI - Psychosocial Results from a Phase I Trial of a Nonsurgical Circumcision Device for Adult Men in Zimbabwe UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=112191950&site=ehost-live&scope=site VL - 30 ID - 429 ER - TY - JOUR AB - Aim: Chest pain is a frequent cause of referral to pediatric cardiology departments and leads to unnecessary testing although cardiac etiology is very rare. Recent studies reported that adolescents' chest pain is generally related with psychological disorder. Adolescents prone to have psychological problems more than others. This condition leads to have different social trends which also can be affected from recurrent complaints and ilnesses. The aim of this study is to examine the relationship between chest pain and social trends in adolescents. Methods: A total of 101 adolescents -50 with chest pain and 51 control- were enrolled in this study and 'Social Trends Scale (STS)' was applied to all participants. Cigarette smoking, presence of family problem and monthly income were recorded. Social trends of participants were evaluated in the subtitles of social adaptation, substance avoidance, violence avoidance, school status, family status and 'target and ideals' by 'STS' which included 26 questions. Results: Chest pain group had lower scores in all subtitles compared with controls. Violence avoidance and family status scores were significantly lower in study group. The presence of chest pain with smoking leaded to social impairment and chest pain with smoking decreased the substance avoidance behavior. Chest pain had negative effect on school status with monthly income of the family. Conclusion: Chest pain effects some social trends negatively with some other factors. This social situation which we have observed during the evaluation of adolescents with chest pain enlightens the importance of psychological evaluation and guidance services. Amaç:Adölesanlarda göğüs ağrısı, çocuk kardiyoloji polikliniklerine sık başvuru sebebi olmasına rağmen, nadiren kardiyak etiyolojiye rastlanılmakta ve gereksiz testlereyol açmaktadır. Son çalışmalar, adölesan göğüs ağrısının genellikle psikolojik rahatsızlıklarla ilişkili olduğunu bildirmiştir. Adölesanlar, psikolojik problemlere sahip olmaya, diğer yaş gruplarına göre daha yatkındır. Bu durum, aynı zamanda tekrarlayan şikayet ve hastalıklardan da etkilenebilecek sosyal eğilimlerde değişime yol açmaktadır. Bu çalışmanın amacı, bu yaş grubunda tekrarlayan göğüs ağrısının, sosyal eğilimler ile olan ilişkisini irdelemektir.Gereç ve Yöntem: Elli bir adet (51) göğüs ağrısı olan ve 50 adet sağlam kontrol olmak üzere toplam 101 adölesana, 'Sosyal Eğilimler Anketi' uygulandı. Ayrıca katılımcıların sigara kullanımı, aile içi problem varlığı, aylık gelir durumu kayıt edildi. Sosyal eğilimler anketi ile adölesanların sosyal eğilimleri, sosyal uyum, maddeden kaçınma, şiddetten kaçınma, aile statüsü, okul statüsü, hedef veideal faktörleri başlıkları altında değerlendiren 26 soru yöneltilmekte ve her bir faktör altında toplanan sorulardan faktör ortalama skoru hesaplanmaktadır.Bulgular: Göğüs ağrısı olan adölesanların, tüm faktörler için toplam skorlarının kontrol grubuna gore daha düşük olduğu belirlendi. 'Şiddetten Kaçınma' ve 'Aile Statüsü' skorları anlamlı şekilde düşüktü. Sigara kullanımı ile birlikte göğüs ağrısı varlığının, sosyal uyumu bozduğu, göğüs ağrısı ve sigara kullanımı birlikteliğinin maddeden kaçınma davranışını azalttığı belirlendi. Göğüs ağrısı, aylık gelir durumu ile birlikte 'Okul Statüsü' skorlarınıolumsuz yönde etkilemekteydi. Sonuç: Göğüs ağrısı, bazı faktörlerle birlikte, birtakım sosyal eğilimler üzerine olumsuz yönde etkili idi. Göğüs Ağrısı olan adölesanlara yaklaşımda gözlediğimiz bu sosyal durum, bu gruba verilecek rehberlik hizmetlerine ışık tutacak niteliktedir. AD - Health Sciences University, Keçiören Training and Research Hospital, Pediatric Cardiology, Ankara, Turkey Health Sciences University, Keçiören Training and Research Hospital, Department of Family Medicine, Ankara, Turkey AN - 138047550. Language: English. Entry Date: 20190816. Revision Date: 20190816. Publication Type: Article AU - Kayali, Seyma AU - Tekin, Oguz DB - cin20 DO - 10.18521/ktd.430685 DP - EBSCOhost IS - 2 KW - Chronic Pain -- Psychosocial Factors Chest Pain -- Psychosocial Factors Social Problems -- Evaluation Social Behavior -- Evaluation Child Behavior -- Evaluation Adolescent Behavior -- Evaluation Child Health Adolescent Health Human Child Adolescence Scales Smoking Family Relations Income Adaptation, Psychological Avoidance (Psychology) Substance Abuse -- Psychosocial Factors Violence -- Psychosocial Factors Educational Status Social Behavior Disorders N1 - questionnaire/scale; research; tables/charts. Journal Subset: Biomedical; Middle East. Instrumentation: Social Trends Scale (STS). PY - 2019 SN - 1309-3878 SP - 183-189 ST - Chronic Chest Pain in Adolescents: Is Not Only a Medical Condition, But Also a Social Problem T2 - Konuralp Medical Journal / Konuralp Tip Dergisi TI - Chronic Chest Pain in Adolescents: Is Not Only a Medical Condition, But Also a Social Problem UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=138047550&site=ehost-live&scope=site VL - 11 ID - 237 ER - TY - JOUR AB - BACKGROUND: Headache is the most frequent neurological symptom and the most common manifestation of pain in childhood. Estimates of the prevalence of headache in children and adolescents vary widely (depending on the setting, methodology, and diagnostic criteria applied) and the impact is not well understood. AIM: To quantify the impact of headache in a school population. DESIGN OF STUDY: A questionnaire survey. SETTING: Exeter schools. METHOD: A total of 1037 school children between the ages of 12 and 15 years were surveyed, of whom 49% were female. Main outcome measures were headache frequency, disease-specific impact using the Pediatric Migraine Disability Assessment Score (PedMIDAS), and generic quality of life impact using the Pediatric Quality of Life Inventory (PedsQL4). RESULTS: Twenty per cent of the study population had headache one or more times a week, with an average PedMIDAS score of over 12.1 (and an impact on over 12 days in a 3-month period). Ten per cent of the population had a PedMIDAS score of 16.8 and a PedsQL4 generic quality of life score of 70.1, indicating a poorer quality of life than that of children with asthma, diabetes, or cancer. An average of 0.6 days of school was lost in a 3-month period across all school children. CONCLUSION: There is a significant impact of headache on the quality of life of children. This impact is both unrecognised and unmet. GPs have an important role in identification and management of this problem. AD - Peninsula College of Medicine and Dentistry, Exeter. su1838@eclipse.co.uk AN - 105437664. Language: English. Entry Date: 20091016. Revision Date: 20200708. Publication Type: Journal Article AU - Kernick, D. AU - Reinhold, D. AU - Campbell, J. L. DB - cin20 DO - 10.3399/bjgp09X454142 DP - EBSCOhost IS - 566 KW - Headache -- Epidemiology Quality of Life Absenteeism Adolescence Child England Female Male Prevalence Questionnaires Scales Schools Surveys Human N1 - research. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Instrumentation: Migraine Disability Assessment Scale (MIDAS); Pediatric Quality of Life Inventory (PEDSQL); Quality of Life Inventory (QOLI). NLM UID: 9005323. PMID: NLM19674513. PY - 2009 SN - 0960-1643 SP - 678-681 ST - Impact of headache on young people in a school population T2 - British Journal of General Practice TI - Impact of headache on young people in a school population UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105437664&site=ehost-live&scope=site VL - 59 ID - 649 ER - TY - JOUR AB - Background: Despite a high prevalence and substantial impact of headache, the needs of young sufferers often remain unmet. The aim of this paper is to describe a qualitative investigation by lay researchers (school students), which explores the experience of fellow students with troublesome headache and provides information to help reduce the burden of headache in the school setting. Method: A purposeful sample participated in semi-structured interviews undertaken by students and taped for thematic analysis by students and professional researchers. The setting was a large state secondary school in Exeter, UK. Results: Four themes were identified: health seeking behaviour, emotional response to headache, attitude of others towards the problem and ideas for help. Conclusion: Useful insights can be obtained from developing a research team of patients and professional researchers. A number of children suffer with headache at school, do not get help and in general are fatalistic about their problem. An awareness of the impact of headache in schools is important and simple measures are available that could help reduce its effects. Further qualitative work is needed with teachers, school nurses and parents to reduce the burden of headache in this setting. AD - General Practitioner, St Thomas Health Centre, Exeter Research Assistant, St Thomas Health Centre, Exeter Teacher, West Exe Technology College, Exeter AN - 66765538. Language: English. Entry Date: 20111103. Revision Date: 20181231. Publication Type: Article AU - Kernick, David AU - Reinhold, Deborah AU - Stone, Christine DB - cin20 DO - 10.12968/bjsn.2011.6.7.337 DP - EBSCOhost IS - 7 KW - Headache -- In Adolescence Life Experiences Students, High School -- United Kingdom Qualitative Studies United Kingdom School Health Schools, Secondary Thematic Analysis Semi-Structured Interview Health Behavior Help Seeking Behavior Emotions Coping Attitude to Illness Adolescence Purposive Sample Male Female Audiorecording Primary Health Care N1 - research; tables/charts. Journal Subset: Europe; Nursing; Peer Reviewed; UK & Ireland. Special Interest: Pediatric Care. NLM UID: 101297722. PY - 2011 SN - 1752-2803 SP - 337-341 ST - A qualitative study of headache in school children T2 - British Journal of School Nursing TI - A qualitative study of headache in school children UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=66765538&site=ehost-live&scope=site VL - 6 ID - 574 ER - TY - JOUR AB - Objectives: The relationships among chronic pain, anxiety, and school functioning are complex, and school functioning is often negatively impacted in youth with chronic pain. The objective of this study was to empirically test a model of associations between constructs predicting school functioning in youth with chronic pain to examine the direct effect of anxiety on school attendance and other indicators of school-related disability.Materials and Methods: Participants included 349 youth and their parents (311 mothers and 162 fathers) who attended a multidisciplinary pain clinic. Youth, mothers, fathers, and clinicians completed assessments of clinical outcomes important to family and clinician perceptions of school functioning; youth, mothers, and fathers completed an assessment of youth anxiety. Structural equation modeling was used to examine interrelations among predictors.Results: Measurement and structural models for predicting youth school functioning provided a very good fit of the data to the conceptual model. Anxiety was directly related to problems with school attendance and avoidance, concentration, and keeping up with schoolwork.Discussion: Anxiety was a robust predictor of school functioning across a range of domains. Evaluating anxiety symptoms in pediatric chronic pain will likely facilitate case conceptualization and treatment planning. This study supports a shift in focus from pain to anxiety as the driving force of school impairment in youth with chronic pain. AN - 109646128. Language: English. Entry Date: 20150923. Revision Date: 20160608. Publication Type: journal article. Journal Subset: Biomedical AU - Khan, Kim Anderson AU - Tran, Susan T. AU - Jastrowski Mano, Kristen E. AU - Simpson, Pippa M. AU - Cao, Yumei AU - Hainsworth, Keri R. DB - cin20 DO - 10.1097/AJP.0000000000000181 DP - EBSCOhost IS - 10 N1 - Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Pain and Pain Management. NLM UID: 8507389. PMID: NLM25411857. PY - 2015 SN - 0749-8047 SP - 867-875 ST - Predicting Multiple Facets of School Functioning in Pediatric Chronic Pain: Examining the Direct Impact of Anxiety T2 - Clinical Journal of Pain TI - Predicting Multiple Facets of School Functioning in Pediatric Chronic Pain: Examining the Direct Impact of Anxiety UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=109646128&site=ehost-live&scope=site VL - 31 ID - 443 ER - TY - JOUR AB - Migraine is one of the most common neurologic conditions in pediatrics. It can be a significant stressor, causing absences from school and interruption of parents' work and family schedules. The mainstay of treatment remains educating patients about healthy lifestyle practices and the influences of sleep, stressors, and hydration on triggering migraine attacks. Psychological therapies such as biofeedback or cognitive-behavioral therapy may be beneficial in some patients, especially those with prominent psychological comorbidities. New advances in the pathophysiology of migraine and additional pediatric approval of abortive therapy with triptans have led to significant advances in the management of migraine in children. Some challenges to preventive therapy were recently noted with the negative results obtained in the Childhood and Adolescent Migraine Prevention Study, which compared prescription drugs to placebo. Inherent differences between adult and pediatric headaches, with shorter duration of pediatric migraine and prominent placebo effect, present recurring challenges for clinicians. [Pediatr Ann. 2018;47(2):e55-e60.]. AD - Departments of Neurology and Pediatrics, The Ohio State University College of Medicine AN - 128056572. Language: English. Entry Date: 20180722. Revision Date: 20190711. Publication Type: journal article AU - Khrizman, Marina AU - Pakalnis, Ann DB - cin20 DO - 10.3928/19382359-20180129-02 DP - EBSCOhost IS - 2 KW - Migraine -- Therapy Health Promotion Combined Modality Therapy Child Cognitive Therapy Biofeedback Analgesics -- Therapeutic Use Migraine -- Psychosocial Factors N1 - review; tables/charts. Journal Subset: Biomedical; USA. NLM UID: 0356657. PMID: NLM29446795. PY - 2018 SN - 0090-4481 SP - e55-e60 ST - Management of Pediatric Migraine: Current Therapies T2 - Pediatric Annals TI - Management of Pediatric Migraine: Current Therapies UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=128056572&site=ehost-live&scope=site VL - 47 ID - 320 ER - TY - JOUR AB - Objective: Headache is the most common type of pain that children and adolescents complain as well as being the most common neurological symptom. Among all school-age children, 15-20% experience headache and 3DS5% of these are migraine. To determine the grade of disability caused by migraine, a specific scale, the Migraine Disability Assessment (MIDAS) questionnaire has been developed. Our objective was to gain information about the evaluation of different types of headaches in adolescents by using the Turkish version of the MIDAS, and to investigate its reliability for differentiation of migraine and tension type headaches. Material and Methods: Eighty two adolescents between the ages of 10 and 16 years were asked questions about the characteristics of their headaches and then the MIDAS questionnaire was administered. The type of headache was then determined according to the International Classification of Headache Disorders Criteria-II (ICHD-II). Results: In 45 patients (54.9%) tension type, in 20 patients (24.4%) migraine, in 10 patients (12.2%) psychogenic type and in seven (8.5%) patients a mixed or non-specific headache was found. It was found that patients with tension type headaches were more likely to have a grade 1score (48.9%) whereas migraine type headache was more common in grade 4 (45%). Conclusion: We believe that modification of the MIDAS questionnaire to meet the needs of adolescent patients will help in the differentiation between different types of headaches. AD - Department of Pediatrics, Division of Adolescent Medicine Division of Pediatric Neurology, Hacettepe University, I.hsan Dog(ramac? ChildrenGT>'s Hospital, Ankara AN - 104546001. Language: Turkish. Entry Date: 20120511. Revision Date: 20200708. Publication Type: Journal Article AU - Kilic, Sait AU - Derman, ORhan AU - Akgul, Sinem AU - Kanbur, Nuray AU - Kutluk, Tezer AU - Aysun, Sabiha DB - cin20 DO - 10.5336/medsci.2011-25330 DP - EBSCOhost IS - 2 KW - Migraine Tension Headache Adolescence Human International Classification of Diseases Questionnaires Scales N1 - research; tables/charts. Journal Subset: Biomedical; Middle East; Peer Reviewed. Instrumentation: Migraine Disability Assessment Scale (MIDAS). PY - 2012 SN - 1300-0292 SP - 466-471 ST - The use of the MIDAS questionnaire to assess migraine and tension type headache in adolescents T2 - Turkiye Klinikleri Journal of Medical Sciences TI - The use of the MIDAS questionnaire to assess migraine and tension type headache in adolescents UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104546001&site=ehost-live&scope=site VL - 32 ID - 558 ER - TY - JOUR AB - Juvenile primary fibromyalgia syndrome (JPFS) involves a triad of chronic pain (diffuse or widespread), fatigue, and sleep disturbance that occurs in children and adolescents. Other associated symptoms are stiffness, subjective feeling of swelling, headache, paresthesias, and irritable bowel syndrome. Patients with JPFS often suffer from depression, which may be primary or secondary. The differential diagnosis is complicated because many patients who have systemic lupus erythematosus or juvenile rheumatoid arthritis also suffer from secondary fibromyalgia. Management includes emotional support, encouragement to return to school and other normal activities, exercise, pharmacotherapy (low starting doses), cognitive behavioral therapy, and support groups. In some cases, formal psychotherapy is necessary. AD - Chief of Pediatric Rheumatology, Hackensack University Medical Center, Hackensack, New Jersey AN - 107109847. Language: English. Entry Date: 20000501. Revision Date: 20150818. Publication Type: Journal Article AU - Kimura, Y. DB - cin20 DP - EBSCOhost IS - 3 KW - Fibromyalgia -- In Infancy and Childhood Fibromyalgia -- In Adolescence Symptoms Diagnosis, Differential Arthritis -- In Infancy and Childhood Chronic Disease Child, Preschool Child Adolescence Male Female N1 - tables/charts. Journal Subset: Allied Health; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 8608119. PY - 2000 SN - 0899-2517 SP - 142-158 ST - Fibromyalgia syndrome in children and adolescents: easily confused with other disorders T2 - Journal of Musculoskeletal Medicine TI - Fibromyalgia syndrome in children and adolescents: easily confused with other disorders UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=107109847&site=ehost-live&scope=site VL - 17 ID - 823 ER - TY - JOUR AB - Chronic pain is a complex integration of biological, psychological, and social variables. Multidisciplinary pain management experts design interventions that treat the multidimensional experience. Children and adolescents with sickle cell disease (SCD) are at risk for chronic pain. Increased risk is associated with multiple characteristics including sickle cell genotype, age, gender, frequency of hospitalization, duration of hospitalization, and certain comorbid diagnoses. Referral to pain management professionals for this population is often delayed. To increase multidisciplinary pain management referrals for youth with SCD identified to be at risk for chronic pain. Implementation research. One pediatric, academic medical facility serving as a regional sickle cell treatment center in the Midwest. Children greater than 2 years of age and less than 21 years of age with laboratory confirmed SCD. Implementation of an evidence-based screening tool using the consolidated framework for implementation research (CFIR) to guide project planning, design, and evaluation. The CFIR model was paired with the Plan-Do-Study-Act (PDSA) quality improvement methodology to operationalize workflow and sustain project aims. Eighty-four percent of all eligible patients were screened during their routine sickle cell appointments resulting in a 110% increase in multidisciplinary pain management referrals. Future interventions and PDSA cycles are targeted at improving attendance at scheduled appointments, reducing hospitalizations, decreasing 30-day readmissions, and shortening length of stay. AD - Children's Mercy Hospital, Integrative Pain Management Clinic, Kansas City, Missouri AN - 146345929. Language: English. Entry Date: 20201018. Revision Date: 20201018. Publication Type: Article AU - Kingsley, Rae Ann DB - cin20 DO - 10.1016/j.pmn.2020.03.005 DP - EBSCOhost IS - 5 KW - Quality Improvement Multidisciplinary Care Team Pain Management Referral and Consultation Chronic Pain -- Risk Factors Anemia, Sickle Cell -- In Adolescence Human Academic Medical Centers Conceptual Framework Descriptive Statistics Child, Preschool Child Adolescence Young Adult Readmission Length of Stay Male Female Midwestern United States N1 - research; tables/charts. Journal Subset: Blind Peer Reviewed; Core Nursing; Editorial Board Reviewed; Expert Peer Reviewed; Nursing; Peer Reviewed; USA. NLM UID: 100890606. PY - 2020 SN - 1524-9042 SP - 403-409 ST - A Healthcare Improvement Initiative to Increase Multidisciplinary Pain Management Referrals for Youth with Sickle Cell Disease T2 - Pain Management Nursing TI - A Healthcare Improvement Initiative to Increase Multidisciplinary Pain Management Referrals for Youth with Sickle Cell Disease UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=146345929&site=ehost-live&scope=site VL - 21 ID - 169 ER - TY - JOUR AB - Background: Intranasal sphenopalatine ganglion (SPG) block has been shown to be an effective treatment for headaches. Multiple therapeutic agents have been studied, although the wide availability and low cost of lidocaine and bupivacaine have made them attractive treatment options. To the authors knowledge, no study has yet demonstrated superiority of one anesthetic over the other.Objective: To determine the efficacy of lidocaine versus bupivacaine when performing intranasal sphenopalatine ganglion (SPG) block for the treatment of headaches.Study Design: Retrospective cohort study.Setting: A single tertiary care academic institutionMETHODS: This retrospective study identified patients who underwent SPG block at a single institution from January 1, 2014 to December 20, 2017. Patients were included if they were treated with either lidocaine or bupivacaine and had both pre- and post-procedure pain scores recorded on a 0-10 scale. Patients were excluded if they were less than 18 years of age.Results: 386 total procedures were performed. 303 (78.5%) were lidocaine delivered via the SphenoCath device, and 83 (21.5%) were bupivacaine delivered via the Tx360 device. 90.2% of treatments (n = 348) decreased the patient's pain level. Of the treatments performed with lidocaine, 89.1% (n = 270) resulted in improvement of the patient's pain level with a mean decrease in pain level of 3.1 (SD ± 2.3). Of the treatments performed with bupivacaine, 94.0% (n = 78) resulted in improvement of the patient's pain level, with a mean decrease in pain level of 3.0 (SD ± 1.9). No statistically significant difference was found between the 2 anesthetics.Limitations: The retrospective study design may introduce selection bias. Both lidocaine and bupivacaine were administered by different devices (Sphenocath and Tx360 respectively) which may account for differences in initial treatment success. There were differences in the size of the two groups, which may also introduce error.Conclusions: This study demonstrates similar efficacy of SPG block performed with lidocaine or bupivacaine. While no difference was found, the particular advantages and disadvantages of the intranasal delivery device may influence physician choice.Key Words: Sphenopalatine ganglion nerve block, lidocaine, bupivacaine, sphenocath, Tx360, pain intervetnio, headache, miimally invasive therapy. AD - University of Kansas Medical Center, Department of Radiology, Kansas City, KS AN - 145105368. Language: English. Entry Date: 20200923. Revision Date: 20201126. Publication Type: journal article AU - Kirkpatrick, Daniel L. AU - Townsend, Tricia AU - Walter, Carissa AU - Clark, Lauren AU - Alli, Adam AU - Fahrbach, Thomas AU - Madarang, E. John AU - Lemons, Steven AU - Reeves, Alan AU - Collins, Zachary DB - cin20 DP - EBSCOhost IS - 4 KW - Headache -- Diagnosis Bupivacaine -- Administration and Dosage Nerve Block -- Methods Lidocaine -- Administration and Dosage Headache -- Drug Therapy Anesthetics, Local -- Administration and Dosage Pain -- Drug Therapy Pain -- Diagnosis Retrospective Design Middle Age Prospective Studies Male Treatment Outcomes Human Adolescence Female Adult Validation Studies Comparative Studies Evaluation Research Multicenter Studies N1 - research. Journal Subset: Biomedical; Peer Reviewed; USA. Instrumentation: Wide Range Achievement Test (WRAT). NLM UID: 100954394. PMID: NLM32709177. PY - 2020 SN - 1533-3159 SP - 423-428 ST - Lidocaine Versus Bupivacaine in the Treatment of Headache with Intranasal Sphenopalatine Nerve Block T2 - Pain Physician TI - Lidocaine Versus Bupivacaine in the Treatment of Headache with Intranasal Sphenopalatine Nerve Block UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=145105368&site=ehost-live&scope=site VL - 23 ID - 182 ER - TY - JOUR AB - This study examines recurrent psychosomatic symptoms and symptom clusters among 5th and 6th grade Israeli school children. A questionnaire which asked about the frequency of eight psychosomatic and eight organic complaints was administered to 259 students. The most frequently reported psychosomatic complaints were abdominal pain, experienced often by 21%, and headache, experienced often by 20% of the pupils. There were statistically significant differences between the sexes, girls having a higher prevalence than boys for eight of the symptoms, and with more girls than boys reporting more than one symptom in each category: 23% of the students had more than one psychosomatic symptom and 16% had more than one organic symptom. Multiple psychosomatic complaints were common, with 28% of those with back or limb pain and 27% of those suffering from 'bad mood' reporting an additional three to five complaints. Abdominal pain and headache were each reported as an accompanying complaint in more than 40% of cases for almost every other psychosomatic complaint. The significance of these symptom clusters needs to be explored further as they may have important implications as markers for psychosocial stress. AN - 106100385. Language: English. Entry Date: 20070101. Revision Date: 20150711. Publication Type: Journal Article AU - Knishkowy, B. AU - Palti, H. DA - Summer95 DB - cin20 DP - EBSCOhost IS - 118 KW - Psychophysiologic Disorders -- Psychosocial Factors Child Cluster Analysis Demography Female Israel Male Morbidity Prevalence Psychophysiologic Disorders -- Epidemiology Questionnaires Socioeconomic Factors Human N1 - research. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 0123667. PMID: NLM7676872. PY - 1995 SN - 0001-8449 SP - 351-351 ST - Symptom clusters among young adolescents T2 - Adolescence TI - Symptom clusters among young adolescents UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106100385&site=ehost-live&scope=site VL - 30 ID - 849 ER - TY - JOUR AD - Altrecht Eating Disorders Rintveld, Altrecht Mental Health Institute, Oude Arnhemseweg, The Netherlands Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, The Netherlands Department of Psychiatry and Medical Psychology, OLVG, Amsterdam. The Netherlands Department of General Paediatrics, University Medical Center Utrecht, The Netherlands. AN - 104359447. Language: English. Entry Date: 20130201. Revision Date: 20200708. Publication Type: Journal Article AU - Knook, L. M. AU - Lijmer, J. G. AU - Konijnenberg, A. Y. AU - Hordijk, P. M. AU - van Engeland, H. DB - cin20 DO - 10.1111/j.1651-2227.2012.02766.x DP - EBSCOhost IS - 9 KW - Chronic Pain -- Epidemiology Educational Status Quality of Life Adolescence Child Comorbidity Female Health Status Indicators Human Male Mental Disorders -- Epidemiology Questionnaires Referral and Consultation N1 - research. Journal Subset: Biomedical; Continental Europe; Europe; Peer Reviewed. Special Interest: Pediatric Care. Instrumentation: Short Form-36 Health Survey (SF-36). NLM UID: 9205968. PMID: NLM22734701. PY - 2012 SN - 0803-5253 SP - 957-963 ST - Quality of life and academic functioning 6 years after paediatric referral for chronic pain T2 - Acta Paediatrica TI - Quality of life and academic functioning 6 years after paediatric referral for chronic pain UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104359447&site=ehost-live&scope=site VL - 101 ID - 547 ER - TY - JOUR AB - Purpose: Internet addiction (IA) is an increasing health problem worldwide. This study aimed to investigate the impact of IA on male and female adolescents and on their academic, sports, and recreative activities. Method: The study was cross-sectional. Adolescents (N = 1291; mean = 16.2 ± 1.1 year) were questioned on the following factors: smart phone, iPad, and computer use; daily internet use time; academic success; success in sports activities. Results: The IA ratio of the whole group was 25.2%, but it was significantly higher in the female group (35.5%; p = 0.00). When we divided the group according to gender, age (p = 0.002), smart phone use (p = 0.045), sports activity (p = 0.000), sports success (p = 0.000), and healthy eating (p = 0.000) were higher in males; duration of daily internet use (p = 0.00), recreative activity (p = 0.021), musculoskeletal pain (p = 0.000), morning stiffness (p = 0.017), difficulty concentrating (p = 0.000), headaches (p = 0.000), numbness in hands (p = 0.011), forgetfulness (p = 0.000), gastrointestinal problems (p = 0.021), dizziness/imbalance (p = 0.001), and IA (p = 0.000) were higher in females. Conclusion: Although the use of mobile phones was lower in the adolescent female group, daily smartphone use times, IA, IA scores, and somatoform symptoms were found to be higher, independent of body mass index. IA has adverse effects on mental and physical health in adolescents. It is necessary to raise awareness in this regard to ensure the transition into healthy adults. AD - Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Kahramanmaraş Sütçü İmam University, Onikişubat, 46000, Kahramanmaraş, Turkey AN - 137721112. Language: English. Entry Date: 20190730. Revision Date: 20190730. Publication Type: Article AU - Koca, Tuba Tülay AU - Berk, Ejder DB - cin20 DO - 10.1007/s10389-018-0965-x DP - EBSCOhost IS - 4 KW - Internet Addiction -- Complications -- In Adolescence Academic Performance -- Evaluation Sports Participation -- Evaluation Recreation -- Evaluation Human Male Female Descriptive Statistics Cross Sectional Studies Adolescence Smartphone -- Utilization Sex Factors Headache -- Risk Factors Hypesthesia -- Risk Factors Memory Gastrointestinal Diseases -- Risk Factors Dizziness -- Risk Factors Body Mass Index Mental Disorders -- Risk Factors Data Analysis Software Adolescent Behavior Health Behavior -- Evaluation Eating Behavior -- Evaluation Internet -- Utilization N1 - research; tables/charts. Journal Subset: Continental Europe; Europe; Peer Reviewed; Public Health. NLM UID: 9425271. PY - 2019 SN - 0943-1853 SP - 531-536 ST - Influence of internet addiction on academic, sportive, and recreative activities in adolescents T2 - Journal of Public Health (09431853) TI - Influence of internet addiction on academic, sportive, and recreative activities in adolescents UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=137721112&site=ehost-live&scope=site VL - 27 ID - 225 ER - TY - JOUR AB - Aim: To measure the fibromyalgia syndrome (FMS) knowledge of female patients admitted to a Physical Medicine and Rehabilitation outpatient clinic. Subjects and methods: One hundred seventy-two (N = 172) literate women aged 18–75 years were included in the study. FMS diagnosis was based on the American College of Rheumatology (ACR) 2010 Classification Criteria. Participants' age, height, weight, level of education and occupations were recorded. The participants were given a questionnaire consisting of 20 questions. The answers were given as true or false. Results: The participants were mainly housewives (52.9%) graduated from primary/middle school (43%). The median number of right answers was 10 (15.7%) with a positive correlation with education level (r = 0.189; p = 0.013). The majority of the participants knew that FMS was characterized by widespread pain as a disease more common in women. However, the false beliefs that the disease was inflammatory, develops deformities in the joints and reduces fertility reduction were not low. Conclusion: Patients' knowledge of the characteristics and long-term outcome of this multifaceted disease contributes to the control of disease. Therefore, patient education programs are important as a complementary treatment in FMS. AD - Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Sütçü İmam University, Kahramanmaraş, Turkey Department of Neurology, Faculty of Medicine, Sütçü İmam University, Kahramanmaraş, Turkey AN - 137721117. Language: English. Entry Date: 20190730. Revision Date: 20190730. Publication Type: Article AU - Koca, Tuba Tülay AU - Tugan, Cemile Buket AU - Koçyiğit, Burhan Fatih AU - Nacitarhan, Vedat DB - cin20 DO - 10.1007/s10389-018-0970-0 DP - EBSCOhost IS - 4 KW - Fibromyalgia -- Rehabilitation Physical Medicine Rehabilitation Patients -- Psychosocial Factors Health Knowledge Women's Health Health Promotion Human Female Adolescence Adult Middle Age Aged Body Height Body Weight Educational Status Questionnaires Descriptive Statistics Patient Education Data Analysis Software Spearman's Rank Correlation Coefficient Body Mass Index Outpatients Fibromyalgia -- Psychosocial Factors N1 - research; tables/charts. Journal Subset: Continental Europe; Europe; Peer Reviewed; Public Health. NLM UID: 9425271. PY - 2019 SN - 0943-1853 SP - 491-497 ST - Fibromyalgia awareness in women aged between 18 and 75 years: a current view to fibromyalgia T2 - Journal of Public Health (09431853) TI - Fibromyalgia awareness in women aged between 18 and 75 years: a current view to fibromyalgia UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=137721117&site=ehost-live&scope=site VL - 27 ID - 224 ER - TY - JOUR AB - Purpose: Posterior elbow impingement can cause disabling pain and limited motion during activities involving elbow extension. Less understood is whether arthroscopic treatment, compared to open surgery, can result in effective management of pain, loss of range of motion, and return athletes to previous levels of activity. This study determined whether arthroscopic debridement is a safe and effective treatment for posterior elbow impingement and whether it enables athletes to return to a previous level of function.Methods: A retrospective review of 36 consecutive patients that underwent arthroscopic debridement of the posterior elbow was performed. There were 34 male and 2 female patients, with a median age of 32 years (17-54 years). There were 7 professional athletes, 6 college athletes, and 23 high school or recreational athletes. All patients had a positive posterior impingement test for posterior pain with extension and limitations of activity. Arthroscopic debridement and additional surgical procedures were performed, and patients underwent follow-up visits at a median 51 months (range 14-81).Results: Significant improvements were seen in pain, motion, and function. No neurovascular complications were seen related to the arthroscopic debridement. The mean Andrews and Timmerman elbow score improved from 159 ± 27 to 193 ± 11 (p < 0.01). Thirty-five of thirty-six (97%) patients returned to their previous level of activity, including all professional athletes.Conclusions: Arthroscopic management of posterior elbow impingement is safe and effective and can return patients, including professional athletes, to high-level athletic activity. Athletes with symptomatic posterior elbow impingement can be successfully and safely treated with arthroscopic debridement and typically will return to preinjury levels of activity.Level Of Evidence: IV. AD - NorthShore Orthopaedic Institute, NorthShore University HealthSystem, 2650 Ridge Avenue Suite 2505, 60201, Evanston, IL, USA California Sports and Orthopaedic Institute, 2999 Regent Street Suite 225, 94705, Berkeley, CA, USA Department of Orthopaedic Surgery, Hospital for Special Surgery, 535 East 70th Street, 10021, New York, NY, USA AN - 127103401. Language: English. Entry Date: 20180720. Revision Date: 20190628. Publication Type: journal article. Journal Subset: Biomedical AU - Koh, Jason L. AU - Zwahlen, Brad A. AU - Altchek, David W. AU - Zimmerman, Todd A. DB - cin20 DO - 10.1007/s00167-017-4563-1 DP - EBSCOhost IS - 1 KW - Arthroscopy -- Methods Debridement -- Methods Elbow Joint -- Surgery Cumulative Trauma Disorders -- Surgery Adolescence Retrospective Design Male Young Adult Treatment Outcomes Adult Female Prospective Studies Middle Age N1 - Blind Peer Reviewed; Continental Europe; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. NLM UID: 9314730. PMID: NLM28534159. PY - 2018 SN - 0942-2056 SP - 306-311 ST - Arthroscopic treatment successfully treats posterior elbow impingement in an athletic population T2 - Knee Surgery, Sports Traumatology, Arthroscopy TI - Arthroscopic treatment successfully treats posterior elbow impingement in an athletic population UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=127103401&site=ehost-live&scope=site VL - 26 ID - 328 ER - TY - JOUR AB - Objectives: Energy drinks contain large amounts of caffeine. Their effects on adolescent well-being are poorly known. We examined the relationship of energy drink consumption with health complaints and late bedtime among 13-year-olds.Methods: A classroom survey was conducted on all 7th graders in the Helsinki metropolitan region, Finland (73 % responded; n = 9446). Logistic regression analysis and structural equation modeling (SEM) were used.Results: The prevalence of health complaints increased as energy drink consumption increased from non-consumers to several times/day. Late bedtime (≥11 PM) increased correspondingly. Those consuming energy drinks several times/day exhibited increased odds of experiencing daily health complaints compared with non-consumers: headache OR (adjusted) = 4.6 (2.8-7.7), sleeping problems OR = 3.6 (2.2-5.8), irritation OR = 4.1 (2.7-6.1), tiredness/fatigue OR = 3.7 (2.4-5.7), and late bedtime OR = 7.8 (5.7-10.9). In SEM, energy drink consumption had a direct effect on health complaints and late bedtime and an indirect effect on health complaints via late bedtime.Conclusions: Energy drinks, late bedtime, and health complaints form a behavior pattern that is worth considering in schools, home and clinical settings when adolescents complain about headaches, problems with sleeping and corresponding symptoms. AD - School of Health Sciences, University of Tampere, 33014 Tampere Finland School of Health Sciences, University of Tampere, 33014, Tampere, Finland Tampere Centre for Childhood, Youth and Family Research (PERLA), University of Tampere, 33014, Tampere, Finland Department of Adolescent Psychiatry, Tampere University Hospital, 33380, Pitkäniemi, Finland AN - 115602761. Language: English. Entry Date: 20170724. Revision Date: 20200308. Publication Type: journal article. Journal Subset: Biomedical AU - Koivusilta, Leena AU - Kuoppamäki, Heini AU - Rimpelä, Arja AU - Kuoppamäki, Heini AU - Rimpelä, Arja DB - cin20 DO - 10.1007/s00038-016-0797-9 DP - EBSCOhost IS - 3 KW - Adolescent Behavior -- Drug Effects Caffeine -- Adverse Effects Sleep -- Drug Effects Energy Drinks -- Adverse Effects Health Status Female Adolescence Male Dose-Response Relationship, Drug Fatigue -- Chemically Induced Headache -- Chemically Induced Logistic Regression Finland Insomnia -- Chemically Induced Scales N1 - Continental Europe; Europe; Public Health. Instrumentation: Clinical Decision Making in Nursing Scale (CDMNS) (Jenkins); Home Observation for Measurement of the Environment (HOME) (Bradley and Caldwell). NLM UID: 101304551. PMID: NLM26888471. PY - 2016 SN - 1661-8556 SP - 299-306 ST - Energy drink consumption, health complaints and late bedtime among young adolescents T2 - International Journal of Public Health (Springer Nature) TI - Energy drink consumption, health complaints and late bedtime among young adolescents UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=115602761&site=ehost-live&scope=site VL - 61 ID - 416 ER - TY - JOUR AB - Background: Migraine is a disabling primary headache disorder that occurs in about 10 % of children and might lead to a lower quality of life. There are several possible migraine triggers in a patient's environment, which should be avoided where possible. The objective of this Austrian monocentric study was to identify migraine triggers and the areas, in which children and adolescents with migraine have a lower quality of life than healthy, headache-free children.Methods: In this cross-sectional, questionnaire study, 76 children from ages 8 to 17 years were included. Thirty-seven were classified as migraineurs, 39 as non-migraineurs. Participants filled in a questionnaire surveying the areas of physical, socio-economic and school functioning. Migraineurs further answered migraine-specific questions.Results: The study included 33 (43.4%) males and 43 (56.6%) females. Median age was 13.00 (10.00-16.00) years. Average age of onset for migraine was 9.22 ± 3.34 years. Non-migraineurs skipped trendwise fewer meals (p.adjust = 0.108) and exercised more often (p.adjust = 0.108). In socio-economic functioning, the father's nationality being Austrian might be related to migraine (p.adjust = 0.108). Children with migraine had a significantly lower quality of life in school functioning (PedsQL 4.0 questionnaire, p.adjust = 0.04) and had significantly less often "good" grades than children without migraine (p.adjust = 0.048).Conclusion: Children with migraine show a reduced quality of life in the areas of physical, socio-economic and school functioning. AD - First Vienna Pediatric Medical Center, Donau-City Straße 1, 1220, Vienna, Austria Sigmund Freud University Vienna, Freudplatz 1, 1020, Vienna, Austria AN - 136647751. Language: English. Entry Date: In Process. Revision Date: 20200614. Publication Type: journal article. Journal Subset: Biomedical AU - Koller, Lydia Stella AU - Diesner, Susanne C. AU - Voitl, Peter DB - cin20 DO - 10.1186/s12887-019-1537-0 DP - EBSCOhost IS - 1 KW - Migraine Quality of Life Adolescence Child Female Surveys Logistic Regression Educational Status Male Austria Cross Sectional Studies Exercise Ferrans and Powers Quality of Life Index N1 - Europe; Peer Reviewed; UK & Ireland. Instrumentation: Pediatric Quality of Life Inventory (PEDSQL); Longitudinal Interval Follow-Up Evaluation (LIFE); Ferrans and Powers Quality of Life Index. NLM UID: 100967804. PMID: NLM31126268. PY - 2019 SN - 1471-2431 SP - N.PAG-N.PAG ST - Quality of life in children and adolescents with migraine: an Austrian monocentric, cross-sectional questionnaire study T2 - BMC Pediatrics TI - Quality of life in children and adolescents with migraine: an Austrian monocentric, cross-sectional questionnaire study UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=136647751&site=ehost-live&scope=site VL - 19 ID - 240 ER - TY - JOUR AB - Purpose: This study aims to determine factor affecting and pain levels the female patients with fibromyalgia. Material and Methods: This descriptive and cross-sectional study was conducted between 15.05.2015 and 15.09.2015 with 104 female participants who had been diagnosed with fibromyalgia. Socio-demographic characteristics were measured by a questionnaire while a quantitative pain scale ranging from 0 to 10 (0=No Pain, 10= Severe Pain) was administered in order to determine pain levels. After ethical board approval was granted, the data were analyzed using descriptive statistics, one-way ANOVA, independent-samples t-test and Pearson correlation. Findings: Research patients had a mean age of 38,87 ± 9,95. Demographic characteristics and the percentages of respondents in them were as follows: elementary school graduation, 48,1%; unemployment, 66,3%; middle-income, more than 50%; overweight/obesity, 51,9% (10 obese patients); non-smokers/ex-smokers, 63,5%. Besides, 31,7% of fibromyalgia patients were suffering also from another disease and 37,5% had been diagnosed fibromyalgia at least for five years. Almost all patients were experiencing pain and the mean pain level was 5,62±2,15. The findings indicated no effects of education, income, and smoking status of female patient with fibromyalgia on their pain levels (p>0,05). On the other hand; unemployment, comorbidity, extended family, overweight/obesity, and the duration of disease (five and more years) were found to have statistically significant effect on higher levels of pain (p<0,05). Age, Body Mass Index (BMI), and marital duration have statistically significant weak positive relationship with pain level (p<0,05). Conclusion: The findings evinced that almost all patients were suffering from pain and age, employment status, family type, BMI, overweight/obesity, marital duration, and disease duration effect pain levels. AD - Sakarya University Institute of Health Science, Department of Nursing, Sakarya, Turkey Assistant Professor, Sakarya University, Faculty of Health Science, Department of Nursing, Sakarya, Turkey AN - 136698187. Language: English. Entry Date: 20190605. Revision Date: 20191024. Publication Type: Article AU - Konak, Hicran AU - Sert, Havva DB - cin20 DP - EBSCOhost IS - 1 KW - Fibromyalgia -- Complications Fibromyalgia -- Risk Factors Pain Measurement Women's Health Human Female Descriptive Research Cross Sectional Studies Socioeconomic Factors Questionnaires Quantitative Studies One-Way Analysis of Variance Descriptive Statistics T-Tests Pearson's Correlation Coefficient Adult Middle Age Age Factors Employment Status Family Characteristics Body Mass Index Obesity Marital Status Disease Duration Scales Interviews N1 - research; tables/charts. Journal Subset: Continental Europe; Europe; Nursing; Peer Reviewed. Special Interest: Women's Health. Instrumentation: Quantitative Pain Scale. PY - 2019 SN - 1791-5201 SP - 224-230 ST - Pain Levels in Female Patients with Fibromyalgia and Affecting Factors T2 - International Journal of Caring Sciences TI - Pain Levels in Female Patients with Fibromyalgia and Affecting Factors UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=136698187&site=ehost-live&scope=site VL - 12 ID - 252 ER - TY - JOUR AB - CONTEXT: There is very little general evidence to support the clinical management, particularly diagnosis, of medically unexplained chronic pain (UCP) in children. OBJECTIVE: We sought to assess in children with UCP if clinical characteristics held important by general pediatricians help to accurately diagnose psychiatric morbidity and, alternatively, if the same can be achieved using dedicated questionnaires. METHODS: We used a cross-sectional diagnostic study in a pediatric outpatient clinic of a university hospital. Our participants were 134 patients, aged 8 to 18 years, who were referred for UCP. Performed were (1) diagnostic test reflecting the pediatricians' choice of clinical characteristics and (2) selected questionnaires. Classification was performed according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, by a child psychiatrist using the Diagnostic Interview Schedule for Children-Parent Version IV and the Semi-structured Clinical Interview for Children and Adolescents. Results were analyzed by logistic regression. RESULTS: Psychiatric morbidity was present in 80 of the children. A minority had a medical explanation for the pain (15% definite, 17% probable). The clinical diagnostic model included age, social-problem indicators, family structure, parental somatization, and school problems. In the quintile of children in whom this model predicted the highest risk, 93% indeed had psychiatric morbidity at reference testing. In the quintile with the lowest predicted risk, indeed only 27% had psychiatric morbidity. The Dutch Personality Inventory for Youth and the Child Behavior Checklist matched the pediatricians' choice of clinical characteristics. In the quintile of children with the highest predicted risk based on these questionnaires, 89% had psychiatric morbidity. In the quintile with the lowest predicted risk, only 15% had psychiatric morbidity. CONCLUSIONS: A pediatrician-chosen set of clinical characteristics of children with UCP proves useful in diagnosing psychiatric morbidity. Using selected questionnaire screening yields similar results. AD - Department of General Pediatrics, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, Netherlands AN - 106449854. Corporate Author: Pain of Unknown Origin in Children Study Group. Language: English. Entry Date: 20060602. Revision Date: 20200708. Publication Type: Journal Article AU - Konijnenberg, A. Y. AU - de Graeff-Meeder, E. R. AU - van der Hoeven, J. AU - Kimpen, J. L. L. AU - Buitelaar, J. K. AU - Uiterwaal, C. S. P. DB - cin20 DO - 10.1542/peds.2005-0109 DP - EBSCOhost IS - 3 KW - Chronic Pain -- Psychosocial Factors Mental Disorders -- Diagnosis Adolescence Chi Square Test Child Child Behavior Checklist Confidence Intervals Cross Sectional Studies Data Analysis Software Diagnosis, Psychosocial Interviews Logistic Regression Mental Disorders -- Complications Multivariate Analysis Netherlands Odds Ratio Pediatricians Psychometrics Questionnaires ROC Curve Univariate Statistics Human N1 - research; tables/charts. Journal Subset: Biomedical; Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Instrumentation: Child Behavior Checklist (CBCL) (Achenbach and Edelbrock); Children's Somatization Inventory (CSI); Diagnostic Interview Schedule for Children-Parent Version IV; Semi-structured Clinical Interview for Children and Adolescents; Dutch Personality Inventory for Youth and the Child; Child Health Questionnaire Child Form (CHQ-CF); Checklist for Family Problems (CFP). NLM UID: 0376422. PMID: NLM16510672. PY - 2006 SN - 0031-4005 SP - 889-897 ST - Psychiatric morbidity in children with medically unexplained chronic pain: diagnosis from the pediatrician's perspective T2 - Pediatrics TI - Psychiatric morbidity in children with medically unexplained chronic pain: diagnosis from the pediatrician's perspective UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106449854&site=ehost-live&scope=site VL - 117 ID - 735 ER - TY - JOUR AB - Aims: To describe and quantify impairment in an outpatient population of children with chronic pain of unknown origin (UCP).Methods: A total of 149 children who presented with pain of at least three months' duration and without a satisfactory explanation at presentation were studied. Number of somatic complaints (Children's Somatisation Inventory, CSI), pain intensity (VAS, 0-10 cm), functional disability (Child Health Questionnaire (CHQ-CF) and clinical history), and general health perceptions (CHQ) were determined.Results: Mean age of the children was 11.8 years; 73% were girls. Overall, 72% suffered impairment in sports activities, 51% reported absence from school, 40% experienced limitations in social functioning, and 34% had problems with sleeping. Mean number of somatic symptoms differed significantly between boys (8.4) and girls (10.7). The CHQ-CF scores for physical functioning, role/social functioning, and general health perceptions were 76.4, 70.7, and 57.5, respectively, indicating substantial impairment on all domains. The mean pain intensity was 4.7 for current and 7.1 for worst pain. Children solely evaluated by a general practitioner prior to referral reported less, though still substantial, impairment. Low general health perceptions, impaired role/social functioning, high pain intensity, and having headache or musculoskeletal pain were independent predictors of having significant impairment.Conclusions: Referred children with UCP show substantial impairment on multiple domains in daily life. AD - University Medical Centre Utrecht, Department of Psychiatry, A00.241, PO Box 85500, 3508 GA Utrecht, Netherlands; e.deGraeff-Meeder@wkz.azu.nl AN - 106516664. Language: English. Entry Date: 20050923. Revision Date: 20200708. Publication Type: Journal Article AU - Konijnenberg, A. Y. AU - Uiterwaal, C. S. P. AU - Kimpen, J. L. L. AU - van der Hoeven, J. AU - Buitelaar, J. K. AU - de Graeff-Meeder, E. R. DB - cin20 DO - 10.1136/adc.2004.056820 DP - EBSCOhost IS - 7 KW - Activities of Daily Living Chronic Pain -- Psychosocial Factors -- In Infancy and Childhood Quality of Life Adolescence Chi Square Test Child Confidence Intervals Data Analysis Software Female Kruskal-Wallis Test Logistic Regression Male Mann-Whitney U Test Multivariate Analysis Netherlands Odds Ratio Pain Measurement Questionnaires Scales Somatoform Disorders Test-Retest Reliability Univariate Statistics Visual Analog Scaling Human N1 - research; tables/charts. Journal Subset: Biomedical; Europe; Peer Reviewed; UK & Ireland. Instrumentation: Pediatric Pain Questionnaire (PPQ); Child Health Questionnaire Child Form (CHQ-CF); Children's Somatisation Inventory (CSI). NLM UID: 0372434. PMID: NLM15899922. PY - 2005 SN - 0003-9888 SP - 680-686 ST - Children with unexplained chronic pain: substantial impairment in everyday life T2 - Archives of Disease in Childhood TI - Children with unexplained chronic pain: substantial impairment in everyday life UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106516664&site=ehost-live&scope=site VL - 90 ID - 745 ER - TY - JOUR AB - Objectives: Prevalence estimates of severe chronic pain in pediatric community samples are rare and inconclusive. This study aimed to (1) examine the prevalence of chronic pain severity grades in school children and (2) investigate differences between pain severity grades for pain-related characteristics, including pain locations, sociodemographic characteristics, emotional functioning, insomnia, school factors, and health care utilization.Materials and Methods: This cross-sectional observational study was conducted with 2220 school students in Germany (52% female individuals, age: M=13.0; SD=1.8; range, 10 to 18 y). Pain severity was assessed using the validated Chronic Pain Grades for adolescents. Comparisons between Chronic Pain Grade subgroups of adolescent characteristics were conducted using χ2 tests, Kruskal-Wallis tests, and 1-way analysis of variance.Results: In school students, 31.0% had chronic pain with 8.2% categorized as severe. Individuals with higher pain severity tended to be girls and have multisite pain, more symptoms of depression and generalized anxiety, and a higher emotional burden of pain. Individuals with higher pain severity also reported less school satisfaction, lower perceived school performance, and more insomnia. Pain medication intake and physician visits because of pain were more common in those with more severe pain.Discussion: Severe chronic pain affects nearly 1 in 10 adolescent school students and is associated with several negative health outcomes and increased health care utilization. It is important to ensure that specialized pain treatment programs are available to these students and that they are aware of the different negative health outcomes associated with the pain condition. AD - German Paediatric Pain Centre, Children's and Adolescents' Hospital, Datteln Department of Children's Pain Therapy and Paediatric Palliative Care, Witten/Herdecke University, Faculty of Health, School of Medicine, Witten, Germany AN - 148246895. Language: English. Entry Date: In Process. Revision Date: 20210125. Publication Type: journal article. Journal Subset: Biomedical AU - Könning, Anna AU - Rosenthal, Nicola AU - Brown, Donnamay AU - Stahlschmidt, Lorin AU - Wager, Julia DB - cin20 DO - 10.1097/AJP.0000000000000898 DP - EBSCOhost IS - 2 N1 - Blind Peer Reviewed; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. NLM UID: 8507389. PMID: NLM33165023. PY - 2021 SN - 0749-8047 SP - 118-125 ST - Severity of Chronic Pain in German Adolescent School Students: A Cross-sectional Study T2 - Clinical Journal of Pain TI - Severity of Chronic Pain in German Adolescent School Students: A Cross-sectional Study UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=148246895&site=ehost-live&scope=site VL - 37 ID - 148 ER - TY - JOUR AB - Background: Although paediatric chronic pain is common, it is not yet clear which individuals with chronic pain are likely to seek health care for their pain. The aims of this study were to summarize the current evidence of the characteristics of children and adolescents with chronic pain who consult a physician or use medication for their pain. Additionally, we aimed to expand knowledge by further investigating key and promising, factors in a large community sample of adolescents.Methods: First, using scoping review methodology, studies on health care utilisation in paediatric chronic pain were identified by the systematic literature search. Out of 1,158 articles, 12 were included for data extraction. Second, in a population-based cross-sectional survey, data of N = 2,280 adolescents (10-18 years) and their parents (N = 1,464), were analysed. Univariable logistic and multivariable LASSO regression models were calculated for adolescents with chronic pain (n = 749) to identify predictors of physician visits or analgesics intake due to pain, controlling for acute illness and injury.Results: The scoping review identified higher pain intensity, frequency, severity and pain-related disability as significant individual factors associated with physician consultation. Female sex and higher pain intensity were associated with medication consumption. Multivariable analyses with cross-sectional data revealed only pain-related school absence to be associated with physician consultation; analgesic medication use was associated with school absence and higher pain intensity.Conclusion: Original data from this study support prior findings. School absence and pain intensity, plausible surrogates for pain severity, are the most relevant factors in health care utilisation due to chronic pain.Significance: A scoping summary of existing research on predictors for physician consultation and medication use in children and adolescents with chronic pain is provided. Furthermore, the role of potential predictors for health care utilisation-sociodemographic, pain, school, psychological and parent-related characteristics-is analysed in a population-based cross-sectional survey. Controlling for illness and injuries, and using a strict chronic pain definition, the cross-sectional survey allows conclusions on healthcare utilisation specific to chronic pain in adolescents. AD - German Paediatric Pain Centre, Children's and Adolescents' Hospital, Datteln, Germany Department of Children's Pain Therapy and Paediatric Palliative Care, Faculty of Health, School of Medicine, Witten/Herdecke University, Witten, Germany Department for Business and Health, University of Applied Sciences Bielefeld, Bielefeld, Germany AN - 147698849. Language: English. Entry Date: In Process. Revision Date: 20210210. Publication Type: journal article. Journal Subset: Biomedical AU - Könning, Anna AU - Rosenthal, Nicola AU - Friese, Michelle AU - Hirschfeld, Gerrit AU - Brown, Donnamay AU - Wager, Julia DB - cin20 DO - 10.1002/ejp.1661 DP - EBSCOhost IS - 1 N1 - Blind Peer Reviewed; Continental Europe; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. Grant Information: 01GY1615//Ministry of Education/. NLM UID: 9801774. PMID: NLM32955736. PY - 2021 SN - 1090-3801 SP - 88-106 ST - Factors associated with physician consultation and medication use in children and adolescents with chronic pain: A scoping review and original data T2 - European Journal of Pain TI - Factors associated with physician consultation and medication use in children and adolescents with chronic pain: A scoping review and original data UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=147698849&site=ehost-live&scope=site VL - 25 ID - 154 ER - TY - JOUR AB - Despite the frequency of pain among children, little is known about its effects on learning and school outcomes. The objective of this study was to quantify the association of pain and academic achievement while taking into account the presence of co-occurring emotional symptoms. A population-based stratified random sample of 1239 students aged 8 to 9 years from primary schools in Melbourne, Australia, was recruited for the Childhood to Adolescence Transition Study. Children indicated sites of pain that had lasted for a day or longer in the past month using a pain manikin. Depressive- and anxiety-related symptoms were assessed using child-reported items. National assessment results for reading and numeracy were used to measure academic achievement. Sixty-five percent of children reported pain in at least 1 body site and 16% reported chronic pain. Increasing number of pain sites was associated with poorer reading scores in a dose-response fashion (β = -3.1; 95% confidence interval -4.9 to -1.3; P < 0.001). The association was only partly attenuated when adjusting for emotional symptoms (β = -2.6; 95% confidence interval -4.5 to -0.8; P < 0.001) and was not moderated by emotional symptoms. Children with chronic pain were a year behind their peers in both reading and numeracy. Among primary school students, pain was associated with lower reading scores even after adjusting for the presence of emotional symptoms. Although population-based longitudinal studies will be required to ascertain consistency and possible causality, grounds exist for considering pain and emotional symptoms in the assessment of children with reading difficulties. AD - Centre for Adolescent Health, The Royal Children's Hospital, Melbourne, Victoria, Australia Murdoch Children's Research Institute, Melbourne, Victoria, Australia School and Student Healthcare, City of Helsinki, Finland Children's Hospital, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia Arthritis Research UK Primary Care Centre, Research Institute for Primary Care and Health Sciences, Keele University, Staffordshire, United Kingdom AN - 124841342. Language: English. Entry Date: 20180723. Revision Date: 20210115. Publication Type: journal article. Journal Subset: Biomedical AU - Kosola, Silja AU - Mundy, Lisa K. AU - Sawyer, Susan M. AU - Canterford, Louise AU - van der Windt, Danielle A. AU - Dunn, Kate M. AU - Patton, George C. DB - cin20 DO - 10.1097/j.pain.0000000000000984 DP - EBSCOhost IS - 9 KW - Schools -- Statistics and Numerical Data Students -- Psychosocial Factors Pain -- Epidemiology Learning Male Pain -- Physiopathology Emotions Pain Measurement Prospective Studies Health and Welfare Planning Child Absenteeism Female Regression Social Class Nonparametric Statistics N1 - Continental Europe; Europe; Peer Reviewed. Instrumentation: Learning and Study Strategies Inventory (LASSI). NLM UID: 7508686. PMID: NLM28738407. PY - 2017 SN - 0304-3959 SP - 1825-1830 ST - Pain and learning in primary school: a population-based study T2 - PAIN TI - Pain and learning in primary school: a population-based study UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=124841342&site=ehost-live&scope=site VL - 158 ID - 352 ER - TY - JOUR AB - OBJECTIVE: To examine the association between headache, sense of coherence (SOC), and medicine use for headaches in a community-based sample of adolescents. METHODS: Epidemiological cross-sectional study, encompassing 20 out of 23 schools in the network of health-promoting schools in the county of South Jutland, Denmark. The study population consisted of students from seventh and ninth grade, participation rate 93%, n=1393. The students answered questions on demographic variables, health behavior including medicine use, psychosocial health aspects, and sense of coherence, in an anonymous standardized questionnaire. The outcome measure was self-reported medicine use for headaches. The determinants were headache frequency and SOC measured by Wold and Torsheim's version for children of Antonovsky's 13-item SOC scale. RESULTS: Analyses adjusted for age group, family social class, exposure to bullying, and headache frequency showed increasing odds for medicine use for headaches (hereafter: medicine use) by decreasing SOC. There was no association between SOC and medicine use among students with a rare experience of headaches but a significant and graded association among students with at least weekly experience of headaches, that is, frequency of headaches modified the association between SOC and medicine use. CONCLUSIONS: We found that adolescents with low SOC used medicine to cope with headaches to a greater extent than adolescents with high SOC. AD - Institute of Public Health, University of Copenhagen, Copenhagen, Denmark. AN - 105395514. Language: English. Entry Date: 20091002. Revision Date: 20150711. Publication Type: Journal Article AU - Koushede, V. AU - Holstein, B. E. DB - cin20 DO - 10.1016/j.jadohealth.2008.12.009 DP - EBSCOhost IS - 2 KW - Confidence -- In Adolescence Headache -- Drug Therapy -- In Adolescence Headache -- Epidemiology -- In Adolescence Adolescence Bullying Chi Square Test Conceptual Framework Confidence Intervals Cross Sectional Studies Data Analysis Software Denmark Female Funding Source Health Behavior Logistic Regression Male Multicenter Studies Odds Ratio Questionnaires Scales Self Report Sex Factors Socioeconomic Factors Summated Rating Scaling Surveys Human N1 - research; tables/charts. Journal Subset: Allied Health; Nursing; Peer Reviewed; Public Health; USA. Instrumentation: Health Behavior in School-Aged Children (HBSC) questionnaire; Wold and Torsheim's version of Antonovsky's 13-item sense of coherence (SOC) scale; HBSC Symptom Check List (HSC-SCL). Grant Information: Health Insurance Foundation, the Ministry of Health and the Interior, the Ministry of Social Affairs, and the Nordea Denmark Foundation. NLM UID: 9102136. PMID: NLM19628141. PY - 2009 SN - 1054-139X SP - 149-155 ST - Sense of coherence and medicine use for headache among adolescents T2 - Journal of Adolescent Health TI - Sense of coherence and medicine use for headache among adolescents UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105395514&site=ehost-live&scope=site VL - 45 ID - 654 ER - TY - JOUR AB - STUDY DESIGN: Cluster randomized controlled trial. OBJECTIVE: To evaluate the effect of a very simple education campaign among community-dwelling 8-year-old schoolchildren. SUMMARY OF BACKGROUND DATA: Information has a positive effect on low back pain (LBP) prevention and management. There is sparse evidence on the feasibility and effectiveness of education campaigns focusing on LBP among young schoolchildren. METHODS: A stratified random sample of 12 schools was randomized to an intervention and a control group. Eight-year-old schoolchildren from these schools were given a questionnaire on LBP prevention and management at baseline, and 15 and 98 days later. On day 8, teachers in the intervention group gave the schoolchildren a Comic Book of the Back, while no intervention was carried out in the control group. After adjusting by possible confounders, generalized estimating equations (GEE) models were developed to calculate the probability of 'success' (a score over 80% of the maximum possible one). RESULTS: Six schools (231 children, 46.5%) were assigned to the control group, and 6 (266 children, 53.5%) to the intervention one. At baseline, the percentage of correct answers was above 73% in both groups, with 8 as a median total score in the control group and 7 in the intervention group. GEE showed that the odds ratio for success in the intervention group, when compared with the control group, was 1.61 (95% CI: 1.03-2.52, P = 0.038). CONCLUSION: The handing out of a Comic Book of the Back slightly improves children's knowledge of appropriate methods for the prevention and management of LBP, and the effect remains significant 3 months after intervention. AN - 104904551. Corporate Author: and the Spanish Back Pain Research Network. Language: English. Entry Date: 20110805. Revision Date: 20150711. Publication Type: Journal Article AU - Kovacs, F. AU - Oliver-Frontera, M. AU - Plana, M. N. AU - Royuela, A. AU - Muriel, A. AU - Gestoso, M. DB - cin20 DO - 10.1097/BRS.0b013e3181dccebc DP - EBSCOhost IS - 8 KW - Health Education -- Methods Health Promotion -- Methods Low Back Pain -- Prevention and Control Low Back Pain -- Therapy Attitude to Health Child Female Human Male Program Evaluation Prospective Studies Questionnaires Randomized Controlled Trials School Health Services -- Standards School Health Services -- Statistics and Numerical Data Time Factors N1 - research; randomized controlled trial. Journal Subset: Allied Health; Biomedical; Peer Reviewed; USA. NLM UID: 7610646. PMID: NLM21178836. PY - 2011 SN - 0362-2436 SP - E505-12 ST - Improving schoolchildren's knowledge of methods for the prevention and management of low back pain: a cluster randomized controlled trial T2 - Spine (03622436) TI - Improving schoolchildren's knowledge of methods for the prevention and management of low back pain: a cluster randomized controlled trial UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104904551&site=ehost-live&scope=site VL - 36 ID - 588 ER - TY - JOUR AB - Background: Reliable information on headache characteristics, including frequency and intensity, headache-associated impairment, and use of analgesic medications, may depend on the assessment method used. This study analyzed the correlations between headache characteristics determined in structured interviews and those determined in prospective diary recordings kept by adolescents in the general population. Methods: In this cross-sectional school-based study, a representative sample of 488 adolescents aged 12-18 years were interviewed about headaches experienced during the previous year. Headache diaries for a three-week period were kept by 393 participants: 244 girls (62 %) and 149 (38 %) boys. Results: Most adolescents (88 %) who reported headaches during their interview also recorded headaches in their diary. In contrast, 51 % of those who reported being headache-free during the last year recorded headaches in their diary. In the interviews, frequent headaches (at least 50 % of days during the last year) were reported by 2.9 % of participants, while 25.5 % reported this headache frequency in their diary. Overall, the ratings of headache frequency were significantly higher in diaries than in interviews ( p < 0.001). Significant but low correlations were observed between intensity levels reported retrospectively and prospectively (rho = 0.28; p < 0.001) and between average scores of headache-related impairment reported retrospectively and prospectively (rho = 0.35; p < 0.001). The use of medications by those who reported one or more current headache disorder during their interview was significantly lower in prospective recordings than in the retrospective interview estimates ( p < 0.001). Conclusions: There is inconsistency in the estimates of headache characteristics between retrospective reports and diary recordings. A comprehensive picture of headache complaints among adolescents may be better obtained through a combination of prospective diary recordings and interviews by school health and clinical services. AD - Regional Centre for Child and Youth Mental Health and Child Welfare, Central Norway, Norwegian University of Science and Technology, Trondheim Norway Unit for Applied Clinical Research, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim Norway AN - 113272966. Language: English. Entry Date: 20170324. Revision Date: 20170324. Publication Type: Article AU - Krogh, Anne-Berit AU - Linde, Mattias AU - Larsson, Bo AU - Salvesen, Øyvind DB - cin20 DO - 10.1186/s10194-016-0602-4 DP - EBSCOhost IS - 1 KW - Headache -- Symptoms -- In Adolescence Human Norway Adolescence Structured Interview Diaries Cross Sectional Studies Male Female Child Descriptive Research Descriptive Statistics Analgesics -- Classification Questionnaires Headache -- Epidemiology Multicenter Studies Convenience Sample Schools, Secondary Kappa Statistic Confidence Intervals Spearman's Rank Correlation Coefficient McNemar's Test Sensitivity and Specificity Predictive Value of Tests Post Hoc Analysis N1 - research; tables/charts. Journal Subset: Biomedical; Continental Europe; Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. Special Interest: Pediatric Care. NLM UID: 100940562. PY - 2016 SN - 1129-2369 SP - 1-8 ST - Assessment of headache characteristics in a general adolescent population: a comparison between retrospective interviews and prospective diary recordings T2 - Journal of Headache & Pain TI - Assessment of headache characteristics in a general adolescent population: a comparison between retrospective interviews and prospective diary recordings UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=113272966&site=ehost-live&scope=site VL - 17 ID - 422 ER - TY - JOUR AB - Objective The objective of this secondary analysis of results from a previously published trial () in chronic migraine in children and adolescents was to examine if participants who received cognitive behavioral therapy and amitriptyline reached a greater level of reduction in headache frequency that no longer indicated a recommendation for preventive treatment as compared to those who received headache education and amitriptyline. Background Chronic migraine negatively affects children's home, school, and social activities. Preventive medication therapy is suggested for 5 or more headaches per month. Reduction to one headache day per week or less may suggest that preventive treatment is no longer indicated and provide a clinically relevant outcome for treatment efficacy and patient care. Methods Randomized study participants ( N = 135) kept a daily record of their headache frequency during 20 weeks of treatment and during a 1 year follow-up period. Baseline headache frequency was determined at the end of a 28 day screening period. Post treatment frequency was determined at 20 weeks ( N = 128 completed) and post treatment follow-up was measured 12 months later ( N = 124 completed). A chi-square test of independence was conducted by treatment group and by time point to determine group differences in the proportion of headache days experienced. Results At 20 weeks (post treatment), 47% of the cognitive behavioral therapy plus amitriptyline group had ≤4 headache days per month compared to 20% of the headache education plus amitriptyline group, ( P = .0011), and 32% of the cognitive behavioral therapy plus amitriptyline group had ≤3 headache days per month at 20 weeks compared to 16% of the headache education plus amitriptyline group, ( P = .0304). At the month 12 follow-up, 72% of the cognitive behavioral therapy plus amitriptyline group had ≤4 headache days per month compared to 52% of the headache education plus amitriptyline group, ( P = .0249), and 61% of the cognitive behavioral therapy plus amitriptyline group had ≤3 headache days per month at their month 12 follow-up compared to 40% of the headache education plus amitriptyline group, ( P = .0192). Conclusions Participants who received cognitive behavioral therapy and amitriptyline were more likely than participants who received headache education plus amitriptyline to reach the clinically meaningful outcome of less than or equal to 4 headache days per month at both time points. These results may help inform what treatment outcomes are possible for children and adolescents suffering from chronic migraine and provides further evidence for behavioral treatment to be considered as a key part of a first line treatment regimen. AD - Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati OH, USA Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati OH, USA Headache Center, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati OH, USA Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati OH, USA AN - 114639499. Language: English. Entry Date: 20160425. Revision Date: 20180809. Publication Type: Article AU - Kroner, John W. AU - Hershey, Andrew D. AU - Kashikar ‐ Zuck, Susmita M. AU - LeCates, Susan L. AU - Allen, Janelle R. AU - Slater, Shalonda K. AU - Zafar, Marium AU - Kabbouche, Marielle A. AU - O'Brien, Hope L. AU - Shenk, Chad E. AU - Rausch, Joseph R. AU - Kroon Van Diest, Ashley M. AU - Powers, Scott W. DB - cin20 DO - 10.1111/head.12795 DP - EBSCOhost IS - 4 KW - Cognitive Therapy Amitriptyline Migraine Chronic Disease Human Randomized Controlled Trials Chi Square Test Time Factors Male Female Child Adolescence N1 - research; tables/charts; randomized controlled trial. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 2985091R. PY - 2016 SN - 0017-8748 SP - 711-716 ST - Cognitive Behavioral Therapy plus Amitriptyline for Children and Adolescents with Chronic Migraine Reduces Headache Days to ≤4 Per Month T2 - Headache: The Journal of Head & Face Pain TI - Cognitive Behavioral Therapy plus Amitriptyline for Children and Adolescents with Chronic Migraine Reduces Headache Days to ≤4 Per Month UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=114639499&site=ehost-live&scope=site VL - 56 ID - 415 ER - TY - JOUR AB - OBJECTIVE: The study aims at identifying biopsychosocial risk factors for headache in children and adolescents aged 9 to 14. METHODS: An epidemiological survey was conducted in a randomly drawn population sample of families with children in the above age group. Questionnaires were mailed to parents and children (n=6400), on whose data this report is based. The objective of the study was to establish a profile of risk factors regarding the occurrence of headache. Headache, as the criterion variable, was ranked according to its frequency in the last 6 months (no, rare, monthly, weekly). Independent variables came from 6 domains: health, socioeconomic, family, school, leisure/peers, and psychological factors. Data analysis was conducted via multinomial regression analyses in a 4-step strategy: (1) analysis of age and sex as control variables; (2) analysis of single variables from each of the 6 domains (controlled for age and sex); (3) domain analyses; and (4) comprehensive analysis including all significant variables from the domain analyses. RESULTS: Age and sex explained a small but significant proportion of the variance in headache frequency (3.5%). All health variables, several socioeconomic, and most family- and school-related as well as the psychological variables demonstrated a significant association with the criterion in the single variable models. However, only a few of the variables related to leisure/peer activities reached significance. The domain model comprising health variables explained 27% of the variance, achieving the best model fit, followed by the psychological model with 13%. CONCLUSIONS: The comprehensive model was able to explain one third of the total variance in headache occurrence. Contrary to our hypothesis, the addition of psychosocial variables to health-related predictors did not markedly improve model fit. AN - 105753811. Language: English. Entry Date: 20080627. Revision Date: 20200708. Publication Type: Journal Article AU - Kröner-Herwig, B. AU - Morris, L. AU - Heinrich, M. DB - cin20 DO - 10.1111/j.1526-4610.2007.00945.x DP - EBSCOhost IS - 4 KW - Headache -- Epidemiology Headache -- Etiology Adolescence Age Factors Child Cross Sectional Studies Psychology Questionnaires Regression Risk Factors Sex Factors Socioeconomic Factors Human N1 - research. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 2985091R. PMID: NLM18042227. PY - 2008 SN - 0017-8748 SP - 529-544 ST - Biopsychosocial correlates of headache: what predicts pediatric headache occurrence? T2 - Headache: The Journal of Head & Face Pain TI - Biopsychosocial correlates of headache: what predicts pediatric headache occurrence? UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=105753811&site=ehost-live&scope=site VL - 48 ID - 684 ER - TY - JOUR AD - Jane B. Pettit Pain and Palliative Care Center, Children's Hospital of Wisconsin, Milwaukee, WI, USA. AN - 106144481. Language: English. Entry Date: 20070831. Revision Date: 20150820. Publication Type: Journal Article. Journal Subset: Core Nursing AU - Ladwig, R. J. AU - Khan, K. A. DB - cin20 DP - EBSCOhost IS - 3 KW - School Health Nursing Student Dropouts Chronic Pain -- Complications Pain Measurement Support, Psychosocial N1 - Nursing; Peer Reviewed; USA. NLM UID: 101142025. PMID: NLM17594302. PY - 2007 SN - 1539-0136 SP - 210-212 ST - School health. School avoidance: implications for school nurses T2 - Journal for Specialists in Pediatric Nursing TI - School health. School avoidance: implications for school nurses UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106144481&site=ehost-live&scope=site VL - 12 ID - 707 ER - TY - JOUR AB - Objective The aim of this initiative was to evaluate the clinical impact, patient acceptability, and sustainability of implementing a newly developed evidence-guided migraine education program in an academic headache center. Background Headache is the fifth most common reason for emergency department (ED) visits and accounts for more than 10 million physician visits annually. Successful management of headaches presents a challenge to both primary care providers and neurologists. The catchment area for an academic headache specialty center in a large metropolitan area is over 6 million with an average wait time of over 15 months. This delays diagnosis and impacts patients, thus a Headache Education Active-Waiting Directive (HEAD) was developed to improve patient knowledge and self-care skills among migraine patients awaiting an initial appointment. Methods This was a prospective pre- and post-intervention study. English-speaking adults, aged 18-65 years, referred to the Center for Headache at the University of Toronto for headache consultation between May and December 2012, who had not previously been assessed by a headache specialist, were consented and enrolled. Data on Migraine Disability Assessment (MIDAS) with additional questions on emergency visits, lifestyle, and self-efficacy were collected premigraine and postmigraine education program session. Results Two hundred and forty-eight patients attended the HEAD program and 177 (71%) consented to the study. Detailed predata and postdata were available for 152 participants (mean age 42.5 ± 11.9 years, 86% females); 117/150 (78%) presented with depressive symptoms and 90/146 (62%) presented with anxiety symptoms. One hundred and thirty-seven of 143 (96%) were using headache treatment. Eighty of 137 (58%) were overusing over-the-counter medications and only 21/137 (15%) were on preventative treatment. There was a decrease in the MIDAS scores of participants at postsession testing prior to neurological consultation (pre-MIDAS mean 50.0 ± 64.6 vs post-MIDAS mean 43.2 ± 50.8, P = .046), as well as a decrease in the number of patients requiring ED visit (presession 33 [22%] vs postsession 17 [11%], P = .001). A significant decrease in medication and narcotic overuse after the HEAD program was also observed. Hydration (water intake), morning protein intake, and routine sleep frequency also significantly improved postsession. Controlling for pre-MIDAS score, poor outcome defined as higher post-MIDAS score was statistically associated with lower education level [ F(2,149) = 10.88, P = .001]. The majority (144/167, 86%) of the participants found the HEAD program helpful, with 70/167 (42%) very satisfied and 74/167 (44%) somewhat satisfied. One hundred and thirty-two of 167 (79%) felt empowered after attending the education session, and 152/167 (91%) felt that other patients with headache would benefit from this program. Conclusions The HEAD program, created to help manage lengthy appointment wait times, was associated with lowering migraine-associated disability, decreasing ED visits, reducing medication and narcotic use and overuse. Education empowers patients to take an active role in their care, especially in regards to improving treatment timing and modifiable lifestyle behaviors. This education program can potentially play a role in early intervention for headache patients especially with chronic migraine and medication overuse headache. AD - Center for Headache, Division of Neurology, Women's College Hospital, University of Toronto, Canada ‐Bartolome, V. Lawler, and C. Lay) AN - 127063351. Language: English. Entry Date: 20180109. Revision Date: 20190101. Publication Type: Article AU - Lagman‐Bartolome, Ana Marissa AU - Lawler, Valerie AU - Lay, Christine DB - cin20 DO - 10.1111/head.13194 DP - EBSCOhost IS - 1 KW - Headache -- Education Patient Education Psychological Well-Being Waiting Lists Program Evaluation Academic Medical Centers Patient Attitudes Prospective Studies Experimental Studies Human Adolescence Young Adult Adult Middle Age Aged Scales Male Female Depression Anxiety Outcomes (Health Care) Emergency Service Life Style Early Intervention Headache -- Drug Therapy N1 - research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. Instrumentation: Migraine Disability Assessment Scale (MIDAS). NLM UID: 2985091R. PY - 2018 SN - 0017-8748 SP - 109-117 ST - Headache Education Active-Waiting Directive: A Program to Enhance Well-Being During Long Referral Wait Times T2 - Headache: The Journal of Head & Face Pain TI - Headache Education Active-Waiting Directive: A Program to Enhance Well-Being During Long Referral Wait Times UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=127063351&site=ehost-live&scope=site VL - 58 ID - 325 ER - TY - JOUR AB - Objective .-To evaluate the impact of treatment with rizatriptan 10 mg on jobs and quality of life of patients with migraine. Methods .-Prospective, open-label study at 27 work sites of 20 companies representing diverse labor sectors in Spain. Eligible patients according International Headache Society (IHS) criteria were recruited for the study by on-site physicians and instructed to treat moderate or severe migraine attacks with one tablet of rizatriptan 10 mg. They were asked to complete the study questionnaires (ML-96, SF-36) at baseline, and then 3 months later. Results .-A total of 259 patients (83 men and 176 women) of a mean age of 39 (range 18 to 61 years) completed the study. Only 7% had taken triptans before for treatment of their migraine attacks. After 3 months of rizatriptan therapy, the use of medical services was significantly lower and all tested domains of quality of life had improved ( P < .001). Absenteeism and days worked during migraine attacks also fell significantly during 3 months of rizatriptan therapy as compared with the 3 months before the study ( P < .001). The improvement in productivity was reflected in the significant decreases in lost workday equivalents (decrease from 3.32 to 1.21 days; P < .001) and also in the total number of workdays lost (decrease from 5.16 to 1.82 days; P < .001). Two-thirds of patients described the efficacy of oral rizatriptan as excellent or very good (62%), and 89% preferred it over their usual medications for acute treatment of migraine attacks. Conclusion .-For this employed population of patients with migraine, treatment with rizatriptan significantly improved parameters measuring direct medical costs, work and productivity, and health-related quality of life. In accordance with these findings, direct and indirect costs related to migraine could be substantially reduced by gathering detailed information about the nature of headache, eliminating triggering factors, and instituting effective treatment of migraine attacks. AN - 106086380. Language: English. Entry Date: 20070101. Revision Date: 20200708. Publication Type: Journal Article AU - Láinez, M. J. AU - López, A. AU - Pascual, A. M. DB - cin20 DO - 10.1111/j.1526-4610.2005.05156.x DP - EBSCOhost IS - 7 KW - Heterocyclic Compounds -- Therapeutic Use Migraine -- Drug Therapy Productivity -- Drug Effects Quality of Life Serotonin Agonists -- Therapeutic Use Acute Disease Adolescence Adult Costs and Cost Analysis Female Male Middle Age Migraine -- Economics Prospective Studies Tryptamines Work Environment Human N1 - research. Journal Subset: Biomedical; Peer Reviewed; USA. Instrumentation: Health-Related Quality of Life (HRQOL). NLM UID: 2985091R. PMID: NLM15985105. PY - 2005 SN - 0017-8748 SP - 883-890 ST - Effects on productivity and quality of life of rizatriptan for acute migraine: a workplace study T2 - Headache: The Journal of Head & Face Pain TI - Effects on productivity and quality of life of rizatriptan for acute migraine: a workplace study UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106086380&site=ehost-live&scope=site VL - 45 ID - 746 ER - TY - JOUR AB - Background: Volleyball’s popularity among middle and high school girls continues to rise with many athletes playing the sport year‐round. While up to 40% of high school basketball players consume analgesics frequently to manage sport related pain, there is limited evidence regarding the prevalence of over the counter (OTC) pain medicine use among high school volleyball players. Hypothesis/Purpose: Identify the prevalence of OTC pain medicine use in high school volleyball players and assess its association with prior injury and sports specialization level. Methods: Female volleyball players from 78 high schools were recruited to enroll in this prospective cohort study during the fall 2018 volleyball season. Baseline data were collected on demographic and volleyball characteristics including volume and type of volleyball participation, sport‐related injuries over the previous twelve months, and level of sport specialization. The frequency of OTC pain medication use for pain management not related to menstrual cramps over the previous seven days was also collected. Participants were asked to describe their OTC pain medicine use during practice, matches, or conditioning and the location of pain they were treating. Results: In total, 2,073 female athletes (Age: 15.6 ± 1.1, BMI: 22.4 ± 3.5, Grade: 9‐12) enrolled in the study. Sixty‐nine percent (n=1425) reported no OTC pain medication use over the past seven days, 16.0% (n=332) reported seldom (one day/week) OTC medication use, 12.6% (n=261) reported sometimes (2‐3 days/week) using OTC medications, and 2.7% (n=55) reported frequent (4‐5 days/week) OTC medication use. In the same time period, 24.8% (n=513) used OTC medications during practice, 16.0% (n=331) during matches, and 21.4% (n=443) during conditioning. Across practice, matches, and conditioning OTC medications were most frequently used to control headaches (7‐13%) and knee pain (4‐ 6%). Highly specialized volleyball players were more likely to frequently use OTC medications (4.5%) compared to low (1.97%) and moderately specialized (2.5%) athletes (p=0.001). Of those reporting no OTC medications use, 16.7% (n=238) had an injury in the last year compared 36.4% (n=20) of athletes who frequently used OTC medications also reporting an injury in the last year (p<0.001). Conclusion: Almost one third of female high school volleyball athletes reported using OTC pain medications in the past week. Those with a history of injury and highly specialized athletes were more likely to use OTC medications. Coaches, athletic trainers, and healthcare providers should be aware of trends in the use of OTC medications among volleyball athletes as its popularity continues to rise. AD - University of Wisconsin, WI, USA. San Diego State University, CA, USA. AN - 148128559. Language: English. Entry Date: 20210123. Revision Date: 20210123. Publication Type: Article AU - Lang, Pamela AU - McGuine, Timothy AU - Mack, Lianna AU - Biese, Kevin AU - Bell, David AU - Watson, Andrew AU - Brooks, M. Alison AU - Post, Eric AU - Kliethermes, Stephanie DB - cin20 DO - 10.1177/2325967120S00250 DP - EBSCOhost KW - Muscle Pain -- Drug Therapy Drugs, Non-Prescription -- Therapeutic Use Athletes, High School Volleyball Congresses and Conferences -- Arizona Arizona N1 - abstract; proceedings; research. Supplement Title: 2020 Supplement. Journal Subset: Allied Health; USA. PY - 2020 SN - 2325-9671 SP - 280-281 ST - PREVALENCE OF OVER THE COUNTER PAIN MEDICATION USE AMONG HIGH SCHOOL VOLLEYBALL PLAYERS...Pediatric Research in Sports Medicine Society (PRiSM) 7th Annual Meeting, January 23-25, 2020, Glendale, Arizona T2 - Orthopaedic Journal of Sports Medicine TI - PREVALENCE OF OVER THE COUNTER PAIN MEDICATION USE AMONG HIGH SCHOOL VOLLEYBALL PLAYERS...Pediatric Research in Sports Medicine Society (PRiSM) 7th Annual Meeting, January 23-25, 2020, Glendale, Arizona UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=148128559&site=ehost-live&scope=site VL - 8 ID - 189 ER - TY - JOUR AB - Purpose Of Review: The purpose of this review is to examine the multitude of factors which may impact learning and academic performance in patients with pediatric migraine.Recent Findings: A range of associations of varying degree were noted between pediatric migraine and conditions such as ADHD, learning disabilities, sleep disorders, and psychiatric comorbidities with regard to headache pain and school functioning. Recent literature highlights the importance of sleep in relation to headache, mood disorders, and learning in youth and the emerging role of perfectionism. Children with migraine remain at risk for school related and learning difficulties which may be primarily due to pain, due to other medical and psychiatric comorbidities commonly found in this population, or a combination. The relationships are complex and further studies are needed to clearly elucidate the shared biological and environmental pathophysiologic mechanisms. AD - The George Washington University School of Medicine & Health Sciences, Children's National Hospital, 111 Michigan Ave, NW, 20010, Washington, DC, USA AN - 144769621. Language: English. Entry Date: In Process. Revision Date: 20200728. Publication Type: journal article AU - Langdon, Raquel AU - DiSabella, Marc AU - Strelzik, Jeffrey AU - Fletcher, Angela DB - cin20 DO - 10.1007/s11916-020-00869-5 DP - EBSCOhost IS - 8 N1 - review. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 100970666. PMID: NLM32529391. PY - 2020 SN - 1531-3433 SP - 1-8 ST - Pediatric Migraine and Academics T2 - Current Pain & Headache Reports TI - Pediatric Migraine and Academics UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=144769621&site=ehost-live&scope=site VL - 24 ID - 176 ER - TY - JOUR AB - Objective: To assess the effect of subcutaneous (SC) sumatriptan 6mg as a means of reducing the economic burden of migraine. Study Design: Open and multi-centered; used a pretest, post-test comparison whereby data from a 1-month run-in period on patients' usual treatment were compared with data from a 4-month treatment period with sumatriptan SC. Patients: 198 patients with moderate to severe migraine. Results: Two hours after using usual medication, headache severity was reduced from severe to moderate, mild, or none by 22 percent of the patients and 6 percent were pain-free. Two hours after using sumatriptan SC, 82 percent reported improvement, with 63 percent being pain-free. Following sumatriptan treatment, extrapolation of the data showed a significant decrease in hours of absence from work and 'non-work' activities (p < 0.001). Productivity impairment at work and during 'non-work' activities was also reduced (p < 0.001). The demand for assistance at home and medical care was also less (p <0.001). Applying values for each work and 'non-work' hours for patient's usual treatment yielded indirect costs of 4807 Deutschmark (DM) as of June 6, 1997, 1 DM = $1.7254 (U.S.) per patient per year and direct costs (medical + home care) of 1284 (DM) annually per patient. These costs were reduced during treatment with sumatriptan to 2459 DM and 478 DM annually per patient. Although direct costs were increased by drug costs, treatment with sumatriptan produced a potential annual savings of 467 DM per patient. Conclusion: The study concludes that sumatriptan should be of significant economic benefit in helping to reduce the resource costs of migraine, particularly in patients suffering from severe attacks. AD - Institute for Medical Psychology and Behavioural Neurobiology, University of Tubingen, Tubingen, Germany AN - 107344965. Language: English. Entry Date: 19971101. Revision Date: 20150711. Publication Type: Journal Article AU - Larbig, W. AU - Bruggenjurgen, B. DB - cin20 DP - EBSCOhost IS - 3 KW - Migraine -- Drug Therapy Productivity -- Drug Effects Sumatriptan -- Therapeutic Use Migraine -- Economics Economic Aspects of Illness Productivity -- Economics Pretest-Posttest Design Observational Methods Descriptive Statistics T-Tests Confidence Intervals Absenteeism -- Drug Effects Migraine -- Classification Health Resource Utilization Sensitivity and Specificity Sumatriptan -- Economics Home Health Care -- Economics Adolescence Adult Middle Age Aged Male Female Human N1 - research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. NLM UID: 9010726. PY - 1997 SN - 1059-7565 SP - 237-246 ST - Work productivity and resource consumption among migraineurs under current treatment and during treatment with sumatriptan -- an economic evaluation of acute treatment in moderate to severe migraineurs T2 - Headache Quarterly, Current Treatment & Research TI - Work productivity and resource consumption among migraineurs under current treatment and during treatment with sumatriptan -- an economic evaluation of acute treatment in moderate to severe migraineurs UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=107344965&site=ehost-live&scope=site VL - 8 ID - 842 ER - TY - JOUR AB - In the present school-based study, a convenience sample of 477 students in grades 6-9 and second year in high school from a city and a smaller town recorded daily occurrence and intensity of headaches in a standard paper diary during a 3-week period. Total headache activity (headache sum), number of headache days, intensity level and duration for weekly headaches were estimated. Approximately 85% of the adolescents had experienced headache of any intensity level during the 3-week recording period. On the average, they reported 2.5 headache days per week and a mean intensity level for headache episodes of 1.7. Our estimates for headache of any intensity level (1-5) occurring at least once a week was surprisingly high (73.8%). For the highest intensity level across the whole 3-week period, almost identical proportions of mild and moderate headaches were reported by students (22.3-22.5%), while about twice as many (40.7%) had experienced severe headaches. Girls consistently reported more headaches than boys, in particular of the moderate and severe intensity types. Students in the city also reported more frequent and intense headaches than those in the town. Peak headache activity was observed at noon and in the afternoon and in the days from the middle of the week until weekend. The use of prospective recordings in diaries will further advance our knowledge on the prevalence and characteristics of recurrent headaches among children and adolescents in community samples. AN - 104514267. Language: English. Entry Date: 20120717. Revision Date: 20200708. Publication Type: Journal Article AU - Larsson, Bo AU - Fichtel, Åsa DB - cin20 DO - 10.1007/s10194-011-0410-9 DP - EBSCOhost IS - 2 KW - Headache -- Epidemiology -- In Adolescence Prospective Studies Diaries Sweden Questionnaires Human Adolescence Male Female Pearson's Correlation Coefficient T-Tests Analysis of Variance Repeated Measures Linear Regression Post Hoc Analysis Data Analysis Software Descriptive Statistics Multivariate Analysis of Variance Chi Square Test Severity of Illness Funding Source N1 - research; tables/charts. Journal Subset: Biomedical; Continental Europe; Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. Special Interest: Pain and Pain Management; Pediatric Care. Grant Information: Financial support by Glaxo Welcome, Sweden.. NLM UID: 100940562. PMID: NLM22200765. PY - 2012 SN - 1129-2369 SP - 129-136 ST - Headache prevalence and characteristics among school children as assessed by prospective paper diary recordings T2 - Journal of Headache & Pain TI - Headache prevalence and characteristics among school children as assessed by prospective paper diary recordings UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=104514267&site=ehost-live&scope=site VL - 13 ID - 560 ER - TY - JOUR AB - Background: Several outcome studies have reported on the short- and long-term effects of migraine in selected clinical samples of children and adolescents. However, current knowledge of the course, incidence, and outcome predictors of frequent headaches in early adolescents in community populations is limited, and little is known about the long-term effects. Headache remains untreated in most of these young people. Here we examined the course, incidence, and outcome predictors of frequent headaches (at least once a week) over the long term (14 years) using previously assessed data at the baseline and 1-year follow-up of early adolescents.Methods: Out of an original sample of 2440 who participated in the first two assessments, a sample of 1266 participants (51.9% response rate) aged 26-28 years (mean = 27.2 years) completed an electronic questionnaire comprising questions about their headache frequency and duration at the long-term follow-up. These headache characteristics together with gender, age, parental divorce, number of friends, school absence, impairment of leisure-time activities and seeing friends, pain comorbidity, and emotional (in particular, depressive symptoms) and behavioral problems were analyzed.Results: In these young people, 8.4% reported frequent headaches (at least once a week) at the extended follow-up, while 19% of the participants having such headaches at baseline again reported such levels with a negligible gender difference. Over the follow-up period, 7.4% had developed frequent headaches, and a higher percentage of females reported such headaches (11.3% in females, 1.5% in males). In a multivariate model, frequent headaches at the baseline, gender (worse prognosis in females), impairment of leisure-time activities and seeing friends, and higher level of depressive symptoms significantly predicted headache frequency at the long-term follow-up.Conclusions: Our findings suggest that gender, greater social impairment, and comorbid depressive symptoms are important indicators for both the short- and long-term prognosis of frequent headaches in early adolescents in community populations. AD - Regional Center for Child and Youth Mental Health and Child Welfare - Central Norway, NTNU, Klostergat. 46/48, N-7489, Trondheim, Norway AN - 131619870. Language: English. Entry Date: 20180908. Revision Date: 20190315. Publication Type: Article AU - Larsson, Bo AU - Sigurdson, Johannes Foss AU - Sund, Anne Mari DB - cin20 DO - 10.1186/s10194-018-0908-5 DP - EBSCOhost IS - 1 KW - Headache -- Epidemiology Community Assessment Human Incidence Adult Questionnaires Divorce Leisure Activities Emotions Comorbidity Depression Age Factors Sex Factors Male Female Multivariate Analysis Social Behavior Headache -- Prognosis N1 - research; tables/charts. Journal Subset: Biomedical; Continental Europe; Double Blind Peer Reviewed; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. NLM UID: 100940562. PY - 2018 SN - 1129-2369 SP - 1-1 ST - Long-term follow-up of a community sample of adolescents with frequent headaches T2 - Journal of Headache & Pain TI - Long-term follow-up of a community sample of adolescents with frequent headaches UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=131619870&site=ehost-live&scope=site VL - 19 ID - 288 ER - TY - JOUR AB - Objective.-To examine the prevalence rate, course, annual incidence, and predictors of frequent headaches (at least once a week) in a 1-year longitudinal study of a representative school sample of 2355 adolescents aged 12 to 14 years. Methods.-Information was gathered by means of questionnaires administered to the subjects at school. Results.-The overall prevalence estimates of frequent headaches, including those subjects reporting another type of frequent pain, were 8.1% and 8.9% at the two assessment points (T(1) and T(2)), and 3.3% to 4% for frequent headaches without other frequent pain complaints. Both forms of frequent headaches were about three times more common among girls than boys. Persistence of frequent headaches (with possible pain comorbidity) was high, in that more than one-third of adolescents reporting frequent headaches continued to have such headaches 1 year later. Persistence also increased with age, in particular among 13- to 14-year-old girls. The overall annual incidence of frequent headaches in the whole sample was 6.5%. While incidence was about twice as high among adolescent girls than boys, there was a steady increase among girls, whereas the rates were stable in boys. The results of multivariate regression analyses showed that frequent headaches at 1-year follow-up could be significantly predicted by frequent headaches at first assessment, impairment (reduced leisure time activities), and high depressive symptom scores, in addition to gender (girls had a worse outcome). Conclusions.-Frequent headaches, among girls in early adolescence in particular, should be carefully evaluated, and treatment offered to those who are impaired in their daily life functioning. AD - Department of Child and Adolescent Psychiatry, NTNU, Trondheim, Norway AN - 106491796. Language: English. Entry Date: 20070101. Revision Date: 20200708. Publication Type: Journal Article AU - Larsson, B. AU - Sund, A. M. DB - cin20 DO - 10.1111/j.1526-4610.2005.05137a.x DP - EBSCOhost IS - 6 KW - Headache -- Epidemiology -- In Adolescence Adolescence Chi Square Test Child Descriptive Statistics Female Headache -- Complications Headache -- Prognosis LISREL Male Norway P-Value Prospective Studies Regression Research Instruments Self Report Sex Factors Funding Source Human N1 - research; tables/charts. Journal Subset: Biomedical; Peer Reviewed; USA. Instrumentation: Mood and Feelings Questionnaire (MFQ). Grant Information: Supported by grants from the Research Council of Norway and from the National Council for Mental Health -- Norway. NLM UID: 2985091R. PMID: NLM15953301. PY - 2005 SN - 0017-8748 SP - 684-691 ST - One-year incidence, course, and outcome predictors of frequent headaches among early adolescents T2 - Headache: The Journal of Head & Face Pain TI - One-year incidence, course, and outcome predictors of frequent headaches among early adolescents UR - http://libproxy.temple.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=106491796&site=ehost-live&scope=site VL - 45 ID - 750 ER - TY - JOUR AB - The present survey was addressed to a representative, nationwide sample of Swedish school nurses and 174 (69%) responded. They were asked about their views on: (i) the most usual problems for students that prompt attendance at school nurses' offices; (ii) the causes and management of school children's headaches and (iii) the school nurses' own education with respect to headaches. Headaches were reported to be one of the most common problems among adolescents visiting the school nurses' offices and tension-type headaches were regarded as a more serious school health problem, compared with migraine. Various stressors such as family and peer problems were regarded as important causes of recurrent headaches. In addition, the school nurses mentioned too little physical activity, sleep problems and poor eating habits as related factors, in particular among students with tension-type headaches. Common management approaches used by the school nurses were to provide information about headaches or supportive discussion, recommend follow-up visits, perform vision tests and refer students to a school physician. About one-fifth to one-third of the school nurses often gave analgesic medication to students because of headaches, most commonly used were paracetamol followed by various NSAIDs. Most of the school nurses regarded relaxation training as an 'effective or very effective' treatment for both migraine and tension-type headaches, whereas palliative and prophylactic drug treatments were seen as more effective for migraine. It is suggested that school nurses, who often provide the first line of treatment for school children and adolescents with recurrent headaches, also should administer a cost-effective treatment such as relaxation training in school settings, where many of the headache episodes occur. However, school nurses also need to be properly trained to ensure quality in delivering such treatment approaches. AD - Dept of Public Health and Caring Sciences, Section of Caring Sciences, Uppsala Science Park, Sweden; bo.larsson@medisin.ntnu.no AN - 106708394. Language: English. Entry Date: 20040305. Revision Date: 20200624. Publication Type: Journal Article AU - Larsson, B. AU - Zaluha, M. DB - cin20 DO - 10.1046/j.1471-6712.2003.00216.x DP - EBSCOhost IS - 3 KW - Headache -- Etiology Headache -- Therapy Nurse Attitudes School Health Services -- Utilization Acetaminophen -- Administration and Dosage Adolescence Adult Antiinflammatory Agents, Non-Steroidal -- Administration and Dosage Aspirin -- Administration and Dosage Chi Square Test Child Coefficient Alpha Epidemiological Research Female Headache -- Drug Therapy Headache -- Education Mail Male Mann-Whitney U Test Middle Age Migraine -- Epidemiology Questionnaires Recurrence Referral and Consultation Relaxation -- Education Rural Areas Scales School Health Nursing Schools, Elementary Schools, Middle Schools, Secondary Spearman's Rank Correlation Coefficient Statistical Significance Surveys Sweden Urban Areas Human N1 - research; tables