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High Rates of Bacteremia and Fluoroquinolone Resistance During an Outbreak of Shigellosis Among People Experiencing Homelessness and Opioid Use Disorder in Philadelphia, Pennsylvania
Oglesby, Valencia Torpey, Erin
Oglesby, Valencia
Torpey, Erin
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Journal article
Date
2025-05-16
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Pathology and Laboratory Medicine
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DOI
https://doi.org/10.1093/ofid/ofaf296
Abstract
In 2023, Philadelphia reported an outbreak of Shigella flexneri infections. We evaluated all patients hospitalized in our health system with shigellosis during this outbreak. Sixty-seven patients were hospitalized, and 21 (31.3%) were bacteremic. Trimethoprim-sulfamethoxazole was the only antibiotic with reliable susceptibility. Most patients had housing insecurity and opioid use disorder.
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Citation
Eleanor Stedman, Andrea Molin, Valencia Oglesby, Erin Torpey, Stephanie Spivack, Kaede V Sullivan, Sara Schultz, High Rates of Bacteremia and Fluoroquinolone Resistance During an Outbreak of Shigellosis Among People Experiencing Homelessness and Opioid Use Disorder in Philadelphia, Pennsylvania, Open Forum Infectious Diseases, Volume 12, Issue 5, May 2025, ofaf296, https://doi.org/10.1093/ofid/ofaf296
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Oxford University Press
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Open Forum Infectious Diseases, Vol. 12, Iss. 5
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