Loading...
A PREFORMULATION DEVELOPMENT STUDY FOR THE TRANSUNGUAL DELIVERY OF THE ANTIFUNGAL DRUG ECONAZOLE NITRATE
Li, Cong
Li, Cong
Citations
Altmetric:
Genre
Thesis/Dissertation
Date
2013
Advisor
Committee member
Group
Department
Pharmaceutical Sciences
Permanent link to this record
Collections
Research Projects
Organizational Units
Journal Issue
DOI
http://dx.doi.org/10.34944/dspace/3180
Abstract
Onychomycosis is the most common disease of nails and constitutes about a half of all nail abnormalities. The thickness of the nails become the major challenge in developing a topical formulation for treatment on OM. In this study, penetration enhancers are used to enhance the solubility and permeability of the drug enconazole nitrate into the nail and the skin. It turns out of all the penetration enhancers, thiourea is the best choice because it can improve the solubility and nail penetration of econazole nitrate at the same time.
Description
Citation
Citation to related work
Has part
ADA compliance
For Americans with Disabilities Act (ADA) accommodation, including help with reading this content, please contact scholarshare@temple.edu