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Profiles of Psychosocial and Clinical Functioning in Adolescence and Risk for Later Depression
; Klein, Daniel ; Seeley, John R.
Klein, Daniel
Seeley, John R.
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Post-print
Date
2020-07-28
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Psychology and Neuroscience
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https://doi.org/10.1017/S0033291719002186
Abstract
Background: Most studies examining predictors of onset of depression focus on variable centered regression methods that focus on effects of multiple predictors. In contrast, person-centered approaches develop profiles of factors and these profiles can be examined as predictors of onset. Here, we developed profiles of adolescent psychosocial and clinical functioning among adolescents without a history of major depression. Methods: Data come from a subsample of participants from the Oregon Adolescent Depression Project who completed self-report measures of functioning in adolescence and completed diagnostic and self-report measures at follow-up assessments up to approximately 15 years after baseline. Results: We identified four profiles of psychosocial and clinical functioning: Thriving; Average Functioning; Externalizing Vulnerability and Family Stress; and Internalizing Vulnerability at the baseline assessment of participants without a history of depression at the initial assessment in mid- adolescence. Classes differed in the likelihood of onset and course of depressive disorders, experience of later anxiety and substance use disorders, and psychosocial functioning in adulthood. Moreover, the predictive utility of these classes was maintained when controlling for multiple other established risk factors for depressive disorders. Conclusions: This work highlights the utility of examining multiple factors simultaneously to understand risk for depression.
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Citation
Olino, T. M., Klein, D., & Seeley, J. (2019). Profiles of psychosocial and clinical functioning in adolescence and risk for later depression and other outcomes. Psychological Medicine, 50(12). https://doi.org/10.1017/S0033291719002186
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Cambridge University Press
Originally Published at 10.1017/S0033291719002186
Originally Published at 10.1017/S0033291719002186
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Psychological Medicine, Vol. 50, Iss. 12
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