Loading...
PC19. FIBRIN SEALANTS DO NOT REDUCE THE RATE OF SEROMA FORMATION IN POST-MASTECTOMY BREAST RECONSTRUCTION: A SYSTEMATIC REVIEW AND META-ANALYSIS
Massada, Karen E.M. Wu, Meagan Webster, Theresa K. Panichella, Juliet Coronado, Michael C. Talemal, Lindsay Elmer, Nicholas Araya, Sthefano Brebion, Rohan Baltodano, Pablo A.
Massada, Karen E.M.
Wu, Meagan
Webster, Theresa K.
Panichella, Juliet
Coronado, Michael C.
Talemal, Lindsay
Elmer, Nicholas
Araya, Sthefano
Brebion, Rohan
Baltodano, Pablo A.
Citations
Altmetric:
Genre
Journal article
Date
2022-04-01
Advisor
Committee member
Department
Subject
Permanent link to this record
Collections
Research Projects
Organizational Units
Journal Issue
DOI
http://dx.doi.org/10.1097/01.gox.0000828328.78728.59
Abstract
PURPOSE: Breast reconstruction using Deep Inferior Epigastric Perforator (DIEP) and Latissimus dorsi (LD) flaps following mastectomy are associated with seroma formation. We performed an updated systematic review and meta-analysis on the effects of fibrin sealant on donor site complications following DIEP and LD flap breast reconstruction. METHODS: A comprehensive literature search was conducted in March 2021, using PubMed, OVID, and Cochrane. Articles analyzing the efficacy of fibrin glue in reducing donor site morbidity in DIEP and LD breast reconstruction were included. The outcomes assessed were seroma rate formation and duration of drainage. RESULTS: 17,265 articles were screened, and 9 articles were selected for analysis, which comprised 632 surgical sites in 611 patients. When comparing fibrin glue and quilting to quilting alone, there was no significant difference in seroma formation (Pooled Risk Ratio (RR) 0.51). Similarly comparing fibrin glue alone to no fibrin glue, there was no significant difference in the rate of seroma formation (Pooled RR 1.03). There also was no significant difference in the duration of drainage in those who received fibrin glue versus those who did not (Pooled RR -0.85) and in those who received fibrin glue and quilting versus quilting alone (Pooled RR -2.13). CONCLUSION: The existing literature supports that using fibrin glue is not associated with a decrease in seroma rate formation or drainage duration in DIEP and LD flaps.
Description
Citation
Massada, Karen E M MD1; Wu, Meagan MA2; Webster, Theresa K. BS3; Panichella, Juliet BS3; Coronado, Michael C. BS3; Talemal, Lindsay BS3; Elmer, Nicholas BS2; Araya, Sthefano MD1; Araya, Sthefano MD1; Brebion, Rohan MD3; Baltodano, Pablo A. MD1; Patel, Sameer A. MD1. PC19. FIBRIN SEALANTS DO NOT REDUCE THE RATE OF SEROMA FORMATION IN POST-MASTECTOMY BREAST RECONSTRUCTION: A SYSTEMATIC REVIEW AND META-ANALYSIS. Plastic and Reconstructive Surgery - Global Open 10(4S):p 44, April 2022. | DOI: 10.1097/01.GOX.0000828328.78728.59
Citation to related work
Lippincott, Williams & Wilkins
Has part
Plastic and Reconstructive Surgery Global Open, Vol. 10
ADA compliance
For Americans with Disabilities Act (ADA) accommodation, including help with reading this content, please contact scholarshare@temple.edu