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Expansive Central Ossifying Fibroma of the Right Mandible
Carey, Kelsey Koenigsberg, Robert Kuklani, Riya Deitrick, Paul
Carey, Kelsey
Koenigsberg, Robert
Kuklani, Riya
Deitrick, Paul
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Journal article
Date
2024-01-24
Advisor
Committee member
Department
Radiology
Neuroradiology
Pathology
Oral and Maxillofacial Surgery
Neuroradiology
Pathology
Oral and Maxillofacial Surgery
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DOI
https://doi.org/10.7759/cureus.52863
Abstract
This case report discusses a 28-year-old patient who presented with a large expansile lesion of the right
mandible. A maxillofacial CT showed a 6.7 x 9.1 x 7.6 cm right mandibular cystic mass containing an internal
matrix of ground glass bone, representing a huge odontogenic keratocyte. Upon biopsy of the lesion, the
specimen consisted of non-decalcified irregular fragments of cemento-osseous material, embedded in a
minimally hemorrhagic, cellular fibrous tissue stroma, suggestive of central ossifying fibroma. This case
presents an ossifying fibroma that far exceeds the average size of these masses, which typically range from
1.0 to 2.5 cm at its greatest dimension. The immense size of the lesion seen in this case is rarely
encountered. This case also helps to emphasize the importance of timely diagnosis and complete resection
of the lesion to prevent mass recurrence and possible malignant transformation.
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Citation
Carey K, Koenigsberg R, Kuklani R, et al. (January 24, 2024) Expansive Central Ossifying Fibroma of the Right Mandible. Cureus 16(1): e52863. doi:10.7759/cureus.52863
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Springer Science and Business Media
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Cureus, Vol. 16, Iss. 1
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