Thumbnail Image
Item

A novel application of the Staudinger ligation to access neutral cyclic di-nucleotide analog precursors via a divergent method

Fletcher, M. H.
; 
Burns-Lynch, C. E.
; ; 
Abraham, L. T.
; 
DeBrosse, C. W.
; 
Citations
Altmetric:
Genre
Journal article
Date
2017-06-07
Advisor
Committee member
Group
Department
Chemistry
Subject
Permanent link to this record
http://hdl.handle.net/20.500.12613/8385
Collections
Faculty/Researcher Works
Show all metadata
Files
Thumbnail Image
FletcherEtAl-JournalArticle-2017.pdf
Adobe PDF, 551.05 KB
Research Projects
Organizational Units
Journal Issue
DOI
https://doi.org/10.1039/c7ra06045a
Abstract
Our efforts to develop a scalable and divergent synthesis of cyclic di-nucleotide analog precursors have resulted in (1) an orthogonally protected di-amino carbohydrate as well as (2) the novel application of the Staudinger ligation to provide medium-sized macrocycles featuring carbamate or urea linkages.
Description
Citation
RSC Adv., 2017,7, 29835-29838
Citation to related work
Royal Society of Chemistry
Has part
RSC Advances, Iss. 47
ADA compliance
For Americans with Disabilities Act (ADA) accommodation, including help with reading this content, please contact scholarshare@temple.edu
Embedded videos