Loading...
Examining biopsychosocial predictors of risk for cognitive impairment among a racially diverse sample of men who have sex with men living with HIV
Xavier Hall, Casey D. Okantey, Beth Meng, Zhuo Sabuncu, Crim Lane, Brittany Millender, Eugenia Queiroz, Artur Hyo Kim, Jung Okada, Lorie Gillespie, Avrum
Xavier Hall, Casey D.
Okantey, Beth
Meng, Zhuo
Sabuncu, Crim
Lane, Brittany
Millender, Eugenia
Queiroz, Artur
Hyo Kim, Jung
Okada, Lorie
Gillespie, Avrum
Citations
Altmetric:
Genre
Journal article
Date
2024-05-14
Advisor
Committee member
Department
Urban Health and Population Science
Medicine
Medicine
Permanent link to this record
Collections
Files
Research Projects
Organizational Units
Journal Issue
DOI
https://doi.org/10.1177/20499361241249657
Abstract
Background: Cognitive decline among people living with HIV (PLWH) is growing concern as world populations become increasing older including higher proportions of PLWH. It is vitally important to understand psychosocial predictors of age-related cognitive decline men who
have sex with men (MSM) living with HIV.
Objectives: The current study seeks to examine psychosocial risk factors the contribute to the risk of age-related cognitive impairment as measured by Cardiovascular Risk Factors, Aging, and Incidence of Dementia (CAIDE) score in a racially diverse sample of MSM living with HIV.
Design: The present analysis utilizes data from the baseline (n=196) and 6-month follow-up (n=135) time points of a longitudinal cohort study of PLWH.
Methods: Using a self-report survey, we examine the associations between psychosocial predictors (e.g. trauma, mental health, chronic pain, sleep disturbance, etc.) and risk of dementia using the CAIDE risk score. Analyses include linear and logistic regression.
Results: In adjusted model stress, chronic pain, Black racial identity, and having a sexual identity that is bisexual or another category are all positively associated with CAIDE scores. Childhood sexual abuse history was negatively associated with CAIDE scores indicating a
protective effect. Sleep disorder has a positive association with CAIDE scores after adjusting for the baseline CAIDE scores.
Conclusion: These results indicate modifiable correlates of cognitive risk (stress and chronic pain). Interventions should seek to address these comorbid factors including the consideration of minority stress and stigma. Interventions should seek to reach Black and bisexual men
living with HIV, including possible cultural tailoring to interventions and messaging. Lastly, future research should examine the impact of variation within childhood sexual abuse histories to better understand their association with cognitive impairment later in life. This may include considering the nature, severity, and potential treatment of trauma symptoms.
Description
Citation
Xavier Hall CD, Okantey B, Meng Z, et al. Examining biopsychosocial predictors of risk for cognitive impairment among a racially diverse sample of men who have sex with men living with HIV. Therapeutic Advances in Infectious Disease. 2024;11. doi:10.1177/20499361241249657
Citation to related work
SAGE Publications
Has part
Therapeutic Advances in Infectious Disease, Vol. 11
ADA compliance
Embedded videos
License
Attribution-NonCommercial CC BY-NC