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A-17 | In-Hospital Outcomes of Patients With Gout Complicaited by Acute ST Elevation Myocardial Infarction (STEMI)
Khalid, Yaser Dasu, Kirti Roy, Trinava Umrani, Rohan Dasu, Neethi Gabriel, Nielsen
Khalid, Yaser
Dasu, Kirti
Roy, Trinava
Umrani, Rohan
Dasu, Neethi
Gabriel, Nielsen
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2023-05-18
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https://doi.org/10.1016/j.jscai.2023.100681
Abstract
Background: Previous studies have shown that elevated uric acid and gout could be important risk factors for increased cardiovascular disease. However, there is a scarcity of information regarding in-hospital outcomes for patients have a STEMI with an acute exacerbation of gout. Our study uses the National Inpatient Sample (NIS) to examine outcomes for patients with both acute gout and STEMI on admission. Methods: The NIS was analyzed using ICD-10 codes for patients (>age 18) with gout and concomitant STEMI versus patients with only gout. Data was extracted from the year 2015 to 2019. Patient characteristics (such as age, gender, ethnicity) and hospital characteristics were identified and analyzed. Multivariate logistic and linear regression analysis was used accordingly to adjust for confounders. STATA software was used for statistical analysis. Results: This study included 2,414,860 patients with gout of which 4,465 of these patients had a STEMI. These patients had higher inpatient mortality (OR 10.01, CI: 8.41-11.91, p<0.0001), length of stay (LOS) (+2.24 days, CI: 1.86-2.62, p<0.0001), total hospital charges (THC) ($47,326, CI: $42,019-$52,634, p<0.0001). On secondary analysis, mortality was decreased if the patient was male (OR 0.54, CI: 0.36-0.81, p=0.003). LOS was increased if patients had congestive heart failure (+2.38 days, CI: 1.41- 3.36, p<0.005), acute kidney injury (AKI) (+2.07 days, CI: 1.09-3.05, p<0.0001), for males (+2.06 days, CI: 1.13- 2.97, p<0.024), or black ethnicity (+2.43 days, CI: 1.04 - 3.81, p<0.043). THC were increased if patients developed cardiogenic shock ($127,275, CI: $102,409 - $152,142, p<0.0001), AKI ($30,366, CI: $12,506-$48,2256, p<0.001), for Asian ethnicity ($91,020, CI: $43,597- $138,444, p<0.0001), or male ($26,923, CI: $10,165-$43,680, p<0.002). Conclusions: Based on the results of our study, patients with gout and concomitant STEMI have higher mortality, LOS, and THC. Disclosures: Y. Khalid Nothing to disclose. K. Dasu Nothing to disclose. M. Lee Nothing to disclose. T. Roy Nothing to disclose. R. Umrani Nothing to disclose. N. Dasu Nothing to disclose. N. Gabriel Nothing to disclose.
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Yaser Khalid, Kirti Dasu, Michael Lee, Trinava Roy, Rohan Umrani, Neethi Dasu, Nielsen Gabriel, A-17 | In-Hospital Outcomes of Patients With Gout Complicaited by Acute ST Elevation Myocardial Infarction (STEMI), Journal of the Society for Cardiovascular Angiography & Interventions, Volume 2, Issue 3, Supplement, 2023, 100681, ISSN 2772-9303, https://doi.org/10.1016/j.jscai.2023.100681.
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Elsevier
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Journal of the Society for Cardiovascular Angiography & Interventions, Vol. 2, Iss. 3
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