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Population Genetics, Evolutionary Genomics, and Genome-Wide Studies of Malaria: A View Across the International Centers of Excellence for Malaria Research
Carlton, JM Volkman, SK Uplekar, S Hupalo, DN Pereira Alves, JM Cui, L Donnelly, M Roos, DS Harb, OS Acosta, M
Carlton, JM
Volkman, SK
Uplekar, S
Hupalo, DN
Pereira Alves, JM
Cui, L
Donnelly, M
Roos, DS
Harb, OS
Acosta, M
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Journal Article
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2015-09-01
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10.4269/ajtmh.15-0049
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© The American Society of Tropical Medicine and Hygiene. The study of the three protagonists in malaria-the Plasmodium parasite, the Anopheles mosquito, and the human host-is key to developing methods to control and eventually eliminate the disease. Genomic technologies, including the recent development of next-generation sequencing, enable interrogation of this triangle to an unprecedented level of scrutiny, and promise exciting progress toward real-time epidemiology studies and the study of evolutionary adaptation. We discuss the use of genomics by the International Centers of Excellence for Malaria Research, a network of field sites and laboratories in malaria-endemic countries that undertake cutting-edge research, training, and technology transfer in malarious countries of the world.
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American Society of Tropical Medicine and Hygiene
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The American journal of tropical medicine and hygiene
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