Show simple item record

dc.creatorVaira, Luigi Angelo
dc.creatorGessa, Claudia
dc.creatorDeiana, Giovanna
dc.creatorSalzano, Giovanni
dc.creatorMaglitto, Fabio
dc.creatorLechien, Jerome R.
dc.creatorSaussez, Sven
dc.creatorPiombino, Pasquale
dc.creatorBiglio, Andrea
dc.creatorBiglioli, Federico
dc.creatorBoscolo-Rizzo, Paolo
dc.creatorHopkins, Claire
dc.creatorParma, Valentina
dc.creatorDe Riu, Giacomo
dc.date.accessioned2023-12-21T18:33:33Z
dc.date.available2023-12-21T18:33:33Z
dc.date.issued2022-01-19
dc.identifier.citationVaira, L.A.; Gessa, C.; Deiana, G.; Salzano, G.; Maglitto, F.; Lechien, J.R.; Saussez, S.; Piombino, P.; Biglio, A.; Biglioli, F.; et al. The Effects of Persistent Olfactory and Gustatory Dysfunctions on Quality of Life in Long-COVID-19 Patients. Life 2022, 12, 141. https://doi.org/10.3390/life12020141
dc.identifier.issn2075-1729
dc.identifier.urihttp://hdl.handle.net/20.500.12613/9303
dc.identifier.urihttp://dx.doi.org/10.34944/dspace/9265
dc.description.abstract(1) Background: Persistent olfactory (POD) and gustatory (PGD) dysfunctions are one of the most frequent symptoms of long-Coronavirus Disease 2019 but their effect on the quality of life (QoL) of patients is still largely unexplored. (2) Methods: An online survey was administered to individuals who reported to have had SARS-CoV-2 infection at least 6 months prior with persisting COVID-19 symptoms (using the COVID symptom index), including ratings of POD and PGD, and their physical (PCS) and mental (MCS) components of quality of life were assessed using the standardized short form 12 questionnaire (SF-12). (3) Results: Responses from 431 unique individuals were included in the analyses. The most frequent persistent symptoms were: fatigue (185 cases, 42.9%), olfactory dysfunction (127 cases, 29.5%), gustatory dysfunction (96 cases, 22.3%) and muscle pain (83 cases, 19.3%). Respondents who reported persisting muscle pain, joint pain, fatigue, headache, gastrointestinal disturbances, and dyspnea had significantly worse PCS. Those experiencing persistent fatigue and dyspnea also showed significantly lower MCS. Respondents reporting POD or PGD showed significantly worse QoL, but only pertaining to the MCS. Multiple regressions predicted MCS based on olfactory and marginally on gustatory ratings, but not PCS. Age significantly affected the prediction of PCS but not MCS, and gender and temporal distance from the COVID-19 diagnosis had no effect. (4) Conclusions: POD and PGD are frequent symptoms of the long-COVID-19 syndrome and significantly reduce QoL, specifically in the mental health component. This evidence should stimulate the establishment of appropriate infrastructure to support individuals with persistent CD, while research on effective therapies scales up.
dc.format.extent13 pages
dc.languageEnglish
dc.language.isoeng
dc.relation.ispartofFaculty/ Researcher Works
dc.relation.haspartLife, Vol. 12, Iss. 2
dc.relation.isreferencedbyMDPI
dc.rightsAttribution CC BY
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectSmell
dc.subjectTaste
dc.subjectOlfactory disorders
dc.subjectGustatory disorders
dc.subjectAnosmia
dc.subjectAgeusia
dc.subjectLong-COVID-19
dc.subjectQuality of life
dc.subjectSARS-CoV-2
dc.titleThe Effects of Persistent Olfactory and Gustatory Dysfunctions on Quality of Life in Long-COVID-19 Patients
dc.typeText
dc.type.genreJournal article
dc.description.departmentPsychology and Neuroscience
dc.relation.doihttp://dx.doi.org/10.3390/life12020141
dc.ada.noteFor Americans with Disabilities Act (ADA) accommodation, including help with reading this content, please contact scholarshare@temple.edu
dc.description.schoolcollegeTemple University. College of Liberal Arts
dc.creator.orcidParma|0000-0003-0276-7072
dc.temple.creatorParma, Valentina
refterms.dateFOA2023-12-21T18:33:33Z


Files in this item

Thumbnail
Name:
ParmaEtAl-JournalArticle-2022- ...
Size:
1.091Mb
Format:
PDF

This item appears in the following Collection(s)

Show simple item record

Attribution CC BY
Except where otherwise noted, this item's license is described as Attribution CC BY