The S-adenosylmethionine analog sinefungin inhibits the trimethylguanosine synthase TGS1 to promote telomerase activity and telomere lengthening
Genre
Journal articleDate
2021-11-24Author
Galati, AlessandraScatolini, Livia
Micheli, Emanuela
Bavasso, Francesca
Cicconi, Alessandro
Maccallini, Paolo
Chen, Lu

Roake, Caitlin M.
Schoeftner, Stefan
Artandi, Steven E.
Gatti, Maurizio
Cacchione, Stefano
Raffa, Grazia D.
Group
Lu Chen Lab (Temple University)Fox Chase Cancer Center
Department
Cancer and Cellular BiologySubject
hTRNA methyltransferase
RNA processin
Sinefungin telomerase
Telomerase reverse transcriptase (TERT)
Telomere
Telomere biology disorders (TBDs)
Telomere lengthening
TGS1
Permanent link to this record
http://hdl.handle.net/20.500.12613/9092