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    Mini Brains & More: Stem Cells In Neuroscience

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    Name:
    09-SajeevEtAl-JournalArticle-S ...
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    Genre
    Journal article
    Date
    2022-05-10
    Author
    Sajeev, Nikita
    Menon, Adi
    Kuchibhatla, Vishwanka
    Spangler, Bailey
    Gitlevich, Becca
    Leonard, Brian cc
    Advisor
    Shah, Mansi
    Department
    Psychology and Neuroscience
    Subject
    Stem cells
    Stem cells--Research
    Nervous system--Degeneration
    Permanent link to this record
    http://hdl.handle.net/20.500.12613/8369
    
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    DOI
    http://dx.doi.org/10.34944/dspace/8337
    Abstract
    Everyone has once wondered: what if I were able to go back in time? Fueled either by the Back to the Future franchise or an embarrassing mistake, almost everyone has played around with the idea of returning to an earlier state. Imagine being able to go back to your childhood, before decisions that have brought you to where you are now. Now bring that idea to a much smaller scale. Imagine applying that idea to the cells in our body. Early in development, progenitor (stem) cells have the capability to differentiate into different types (neurons, cardiomyocytes, etc). During development, cells become more specialized over time and as an organism matures, they become more limited in the types of cells they can differentiate into [1]. Scientists are now able to perform cellular “time travel” through induced pluripotent stem cells (iPSCs), taking mature cells back to a stage of pluripotency, when they are able to specialize into almost any cell type (with a few exceptions).
    Citation
    Sajeev, N., Menon, A., Kuchibhatla, V., Spangler, B., Gitlevich, B., & Leonard, B. (2022). Mini brains & more: Stem cells in neuroscience. Grey Matters, 3, pp. 48-53.
    Citation to related work
    Available at: https://greymattersjournaltu.org/issue-3/mini-brains
    Has part
    Grey Matters, Iss. 3, Spring 2031
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    For Americans with Disabilities Act (ADA) accommodation, including help with reading this content, please contact scholarshare@temple.edu
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