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dc.creatorHorwitz, Ralph I.
dc.creatorHayes-Conroy, Allison
dc.creatorSinger, Burton H.
dc.creatorCullen, Mark R.
dc.creatorBadal, Kimberly
dc.creatorSim, Ida
dc.date.accessioned2023-01-06T17:20:50Z
dc.date.available2023-01-06T17:20:50Z
dc.date.issued2022-09-01
dc.identifier.issn1558-8238
dc.identifier.doihttp://dx.doi.org/10.34944/dspace/8225
dc.identifier.urihttp://hdl.handle.net/20.500.12613/8254
dc.description.abstractA recent research report in Science by Bjornevik et al. tested the hypothesis that multiple sclerosis (MS) is caused by Epstein-Barr virus (EBV) in a cohort of more than ten million adults on active duty in the US military during a 20-year period (1993–2013) (1). The authors reported that individuals who had prior EBV infection were 24 times more likely to develop MS than noninfected persons. The findings appear to confirm a longstanding suspicion linking EBV to MS and led many to call for an EBV vaccine to prevent MS. A closer examination of the article, however, indicates the analysis was incomplete and misrepresents the data. In fact, a strong association between EBV and MS was present only for those with recent infection occurring during active-duty military service.
dc.format.extent3 pages
dc.languageEnglish
dc.language.isoeng
dc.relation.ispartofFaculty/Researcher Works
dc.relation.haspartThe Journal of Clinical Investigation, Vol. 132, No. 17
dc.relation.isreferencedbyAmerican Society for Clinical Investigation
dc.rightsAttribution CC BY
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.titleFalling down the biological rabbit hole: Epstein-Barr virus, biography, and multiple sclerosis
dc.typeText
dc.type.genreJournal article
dc.description.departmentCardiovascular Sciences
dc.description.departmentGeography and Urban Studies
dc.relation.doihttps://doi.org/10.1172/jci164141
dc.ada.noteFor Americans with Disabilities Act (ADA) accommodation, including help with reading this content, please contact scholarshare@temple.edu
dc.description.schoolcollegeLewis Katz School of Medicine
dc.description.schoolcollegeTemple University. College of Liberal Arts
dc.temple.creatorHorwitz, Ralph I.
dc.temple.creatorHayes-Conroy, Allison
refterms.dateFOA2023-01-06T17:20:50Z


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