Falling down the biological rabbit hole: Epstein-Barr virus, biography, and multiple sclerosis
dc.creator | Horwitz, Ralph I. | |
dc.creator | Hayes-Conroy, Allison | |
dc.creator | Singer, Burton H. | |
dc.creator | Cullen, Mark R. | |
dc.creator | Badal, Kimberly | |
dc.creator | Sim, Ida | |
dc.date.accessioned | 2023-01-06T17:20:50Z | |
dc.date.available | 2023-01-06T17:20:50Z | |
dc.date.issued | 2022-09-01 | |
dc.identifier.issn | 1558-8238 | |
dc.identifier.doi | http://dx.doi.org/10.34944/dspace/8225 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12613/8254 | |
dc.description.abstract | A recent research report in Science by Bjornevik et al. tested the hypothesis that multiple sclerosis (MS) is caused by Epstein-Barr virus (EBV) in a cohort of more than ten million adults on active duty in the US military during a 20-year period (1993–2013) (1). The authors reported that individuals who had prior EBV infection were 24 times more likely to develop MS than noninfected persons. The findings appear to confirm a longstanding suspicion linking EBV to MS and led many to call for an EBV vaccine to prevent MS. A closer examination of the article, however, indicates the analysis was incomplete and misrepresents the data. In fact, a strong association between EBV and MS was present only for those with recent infection occurring during active-duty military service. | |
dc.format.extent | 3 pages | |
dc.language | English | |
dc.language.iso | eng | |
dc.relation.ispartof | Faculty/Researcher Works | |
dc.relation.haspart | The Journal of Clinical Investigation, Vol. 132, No. 17 | |
dc.relation.isreferencedby | American Society for Clinical Investigation | |
dc.rights | Attribution CC BY | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.title | Falling down the biological rabbit hole: Epstein-Barr virus, biography, and multiple sclerosis | |
dc.type | Text | |
dc.type.genre | Journal article | |
dc.description.department | Cardiovascular Sciences | |
dc.description.department | Geography and Urban Studies | |
dc.relation.doi | https://doi.org/10.1172/jci164141 | |
dc.ada.note | For Americans with Disabilities Act (ADA) accommodation, including help with reading this content, please contact scholarshare@temple.edu | |
dc.description.schoolcollege | Lewis Katz School of Medicine | |
dc.description.schoolcollege | Temple University. College of Liberal Arts | |
dc.temple.creator | Horwitz, Ralph I. | |
dc.temple.creator | Hayes-Conroy, Allison | |
refterms.dateFOA | 2023-01-06T17:20:50Z |