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dc.creatorEshraghi, Jamshid
dc.creatorLongo, John
dc.creatorDalton, David R.
dc.creatorHarrington, George W.
dc.date.accessioned2021-04-16T14:35:08Z
dc.date.available2021-04-16T14:35:08Z
dc.date.issued1990-04
dc.identifier.citationEshraghi, J., Longo, J., Dalton, D.R. and Harrington, G.W. (1990), An Unusual Ring Contraction in the Formation of N‐Nitrosohexamethyleneimine and N‐Nitrosopiperidine from Tolazamide. Japanese Journal of Cancer Research, 81: 324-326. https://doi-org/10.1111/j.1349-7006.1990.tb02570.x
dc.identifier.issn0910-5050
dc.identifier.doihttp://dx.doi.org/10.34944/dspace/6288
dc.identifier.urihttp://hdl.handle.net/20.500.12613/6306
dc.description.abstractThe previously reported reaction of tolazamide with nitrite, under physiological conditions, to form N‐nitrosohexamethyleneimine and surprisingly, N‐nitrosopiperidine was confirmed. By using the six‐membered ring analogue of tolazamide, 1‐(piperidyl)‐3‐(p‐tolylsulfonyl)urea, which yields the corresponding N‐nitrosopiperidine and N‐nitrosopyrrolidine, the present study shows that an unusual ring contraction occurs, excising the carbon alpha to the nitrogen.
dc.format.extent3 pages
dc.languageEnglish
dc.language.isoeng
dc.relation.ispartofFaculty/ Researcher Works
dc.relation.haspartJapanese Journal of Cancer Research, Vol. 81, Iss. 4
dc.relation.isreferencedbyWiley
dc.rightsAll Rights Reserved
dc.subjectTolazamide
dc.subjectN‐Nitrosohexamethyleneimine
dc.subjectN‐Nitrosopiperidine
dc.subjectN‐Nitrosopyrrolidine
dc.titleAn Unusual Ring Contraction in the Formation of N‐Nitrosohexamethyleneimine and N‐Nitrosopiperidine from Tolazamide
dc.typeText
dc.type.genreJournal article
dc.description.departmentChemistry
dc.relation.doihttps://doi.org/10.1111/j.1349-7006.1990.tb02570.x
dc.ada.noteFor Americans with Disabilities Act (ADA) accommodation, including help with reading this content, please contact scholarshare@temple.edu
dc.description.schoolcollegeTemple University. College of Science and Technology
dc.temple.creatorEshraghi, Jamshid
dc.temple.creatorLongo, John
dc.temple.creatorDalton, David R.
dc.temple.creatorHarrington, George W.
refterms.dateFOA2021-04-16T14:35:08Z


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