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    Management of Chlamydia trachomatis genital tract infection: Screening and treatment challenges

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    Name:
    Management of Chlamydia trachomatis ...
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    Genre
    Review
    Journal
    Date
    2011-03-21
    Author
    Taylor, BD
    Haggerty, CL
    Subject
    Chlamydia trachomatis
    chlamydia screening
    chlamydia treatment
    sexually transmitted disease
    Permanent link to this record
    http://hdl.handle.net/20.500.12613/5524
    
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    DOI
    10.2147/IDR.S12715
    Abstract
    Chlamydia trachomatis is a prevalent sexually transmitted infection that can lead to serious reproductive morbidity. Management and control of C. trachomatis is a challenge, largely due to its asymptomatic nature and our incomplete understanding of its natural history. Although chlamydia screening programs have been implemented worldwide, several countries have observed increasing rates of reported chlamydia cases. We reviewed the literature relating to the long-term complications of C. trachomatis, as well as screening strategies, treatment, and prevention strategies for reducing chlamydia in the population. Articles from 1950-2010 were identified through a Medline search using the keyword "Chlamydia trachomatis" combined with "screening", "pelvic inflammatory disease", "endometritis", "salpingitis", "infertility", "ectopic pregnancy", "urethritis", "epididymitis", "proctitis", "prostatitis", "reinfection", "cost- effectiveness", "treatment", "vaccines", or "prevention". Progression of C. trachomatis varies, and recurrent infections are common. Currently, there is limited evidence on the effectiveness of chlamydia screening. Higher quality studies are needed to determine the efficacy of more frequent screening, on a broader range of sequelae, including infertility and ectopic pregnancy, in addition to pelvic inflammatory disease. Studies should focus on delineating the natural history of recurrent infections, paying particular attention to treatment failures. Furthermore, alternatives to screening, such as vaccines, should continue to be explored. © 2011 Taylor and Haggerty, publisher and licensee Dove Medical Press Ltd.
    Citation to related work
    Informa UK Limited
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    Infection and Drug Resistance
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    http://dx.doi.org/10.34944/dspace/5506
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