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dc.creatorClithero, JA
dc.creatorReeck, C
dc.creatorMckell Carter, R
dc.creatorSmith, DV
dc.creatorHuettel, SA
dc.date.accessioned2021-01-31T23:44:32Z
dc.date.available2021-01-31T23:44:32Z
dc.date.issued2011-01-01
dc.identifier.issn1662-5161
dc.identifier.issn1662-5161
dc.identifier.doihttp://dx.doi.org/10.34944/dspace/5504
dc.identifier.other814OQ (isidoc)
dc.identifier.other21941472 (pubmed)
dc.identifier.urihttp://hdl.handle.net/20.500.12613/5522
dc.description.abstractTo dissociate a choice from its antecedent neural states, motivation associated with the expected outcome must be captured in the absence of choice. Yet, the neural mechanisms that mediate behavioral idiosyncrasies in motivation, particularly with regard to complex economic preferences, are rarely examined in situations without overt decisions. We employed functional magnetic resonance imaging in a large sample of participants while they anticipated earning rewards from two different modalities: monetary and candy rewards. An index for relative motivation toward different reward types was constructed using reaction times to the target for earning rewards. Activation in the nucleus accumbens (NAcc) and anterior insula (aINS) predicted individual variation in relative motivation between our reward modalities. NAcc activation, however, mediated the effects of aINS, indicating the NAcc is the likely source of this relative weighting. These results demonstrate that neural idiosyncrasies in reward efficacy exist even in the absence of explicit choices, and extend the role of NAcc as a critical brain region for such choice-free motivation. © 2011 Clithero, Reeck, Carter, Smith and Huettel.
dc.format.extent87-
dc.language.isoeng
dc.relation.haspartFrontiers in Human Neuroscience
dc.relation.isreferencedbyFrontiers Media SA
dc.subjectanticipation
dc.subjectfMRI
dc.subjectinsula
dc.subjectmotivation
dc.subjectnucleus accumbens
dc.subjectreward
dc.titleNucleus accumbens mediates relative motivation for rewards in the absence of choice
dc.typeArticle
dc.type.genreJournal Article
dc.relation.doi10.3389/fnhum.2011.00087
dc.ada.noteFor Americans with Disabilities Act (ADA) accommodation, including help with reading this content, please contact scholarshare@temple.edu
dc.creator.orcidReeck, Crystal|0000-0002-1540-5321
dc.date.updated2021-01-31T23:44:29Z
refterms.dateFOA2021-01-31T23:44:33Z


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