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dc.creatorKusumi, K
dc.creatorKulathinal, RJ
dc.creatorAbzhanov, A
dc.creatorBoissinot, S
dc.creatorCrawford, NG
dc.creatorFaircloth, BC
dc.creatorGlenn, TC
dc.creatorJanes, DE
dc.creatorLosos, JB
dc.creatorMenke, DB
dc.creatorPoe, S
dc.creatorSanger, TJ
dc.creatorSchneider, CJ
dc.creatorStapley, J
dc.creatorWade, J
dc.creatorWilson-Rawls, J
dc.date.accessioned2021-01-31T23:17:21Z
dc.date.available2021-01-31T23:17:21Z
dc.date.issued2011-11-11
dc.identifier.issn1471-2164
dc.identifier.issn1471-2164
dc.identifier.doihttp://dx.doi.org/10.34944/dspace/5477
dc.identifier.other22077994 (pubmed)
dc.identifier.urihttp://hdl.handle.net/20.500.12613/5495
dc.description.abstractBackground: Comparative studies of amniotes have been hindered by a dearth of reptilian molecular sequences. With the genomic assembly of the green anole, Anolis carolinensis available, non-avian reptilian genes can now be compared to mammalian, avian, and amphibian homologs. Furthermore, with more than 350 extant species in the genus Anolis, anoles are an unparalleled example of tetrapod genetic diversity and divergence. As an important ecological, genetic and now genomic reference, it is imperative to develop a standardized Anolis gene nomenclature alongside associated vocabularies and other useful metrics.Results: Here we report the formation of the Anolis Gene Nomenclature Committee (AGNC) and propose a standardized evolutionary characterization code that will help researchers to define gene orthology and paralogy with tetrapod homologs, provide a system for naming novel genes in Anolis and other reptiles, furnish abbreviations to facilitate comparative studies among the Anolis species and related iguanid squamates, and classify the geographical origins of Anolis subpopulations.Conclusions: This report has been generated in close consultation with members of the Anolis and genomic research communities, and using public database resources including NCBI and Ensembl. Updates will continue to be regularly posted to new research community websites such as lizardbase. We anticipate that this standardized gene nomenclature will facilitate the accessibility of reptilian sequences for comparative studies among tetrapods and will further serve as a template for other communities in their sequencing and annotation initiatives. © 2011 Kusumi et al; licensee BioMed Central Ltd.
dc.format.extent554-
dc.language.isoen
dc.relation.haspartBMC Genomics
dc.relation.isreferencedbySpringer Science and Business Media LLC
dc.rightsCC BY
dc.rights.urihttp://creativecommons.org/licenses/by/2.0
dc.subjectAnimals
dc.subjectConserved Sequence
dc.subjectDNA Transposable Elements
dc.subjectEvolution, Molecular
dc.subjectGenetic Markers
dc.subjectGenomics
dc.subjectLizards
dc.subjectMicrosatellite Repeats
dc.subjectRepetitive Sequences, Nucleic Acid
dc.subjectTerminology as Topic
dc.titleDeveloping a community-based genetic nomenclature for anole lizards
dc.typeArticle
dc.type.genreLetter
dc.type.genreJournal
dc.relation.doi10.1186/1471-2164-12-554
dc.ada.noteFor Americans with Disabilities Act (ADA) accommodation, including help with reading this content, please contact scholarshare@temple.edu
dc.creator.orcidKulathinal, Rob|0000-0003-1907-2744
dc.date.updated2021-01-31T23:17:17Z
refterms.dateFOA2021-01-31T23:17:21Z


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