Malaria Molecular Epidemiology: Lessons from the International Centers of Excellence for Malaria Research Network
Genre
Journal ArticleDate
2015-09-01Author
Escalante, AAFerreira, MU
Vinetz, JM
Volkman, SK
Cui, L
Gamboa, D
Krogstad, DJ
Barry, AE
Carlton, JM
van Eijk, AMAPradhan, KMueller, IGreenhouse, BPacheco, MAVallejo, AFHerrera, SFelger, I
Subject
Gene FlowGenetics, Population
Genotyping Techniques
Humans
International Cooperation
Malaria
Malaria, Falciparum
Malaria, Vivax
Molecular Epidemiology
PlasmodiumPlasmodium falciparumPlasmodium vivax
Permanent link to this record
http://hdl.handle.net/20.500.12613/5206Metadata
Show full item recordDOI
10.4269/ajtmh.15-0005Abstract
© The American Society of Tropical Medicine and Hygiene. Molecular epidemiology leverages genetic information to study the risk factors that affect the frequency and distribution of malaria cases. This article describes molecular epidemiologic investigations currently being carried out by the International Centers of Excellence for Malaria Research (ICEMR) network in a variety of malaria-endemic settings. First, we discuss various novel approaches to understand malaria incidence and gametocytemia, focusing on Plasmodium falciparum and Plasmodium vivax. Second, we describe and compare different parasite genotyping methods commonly used in malaria epidemiology and population genetics. Finally, we discuss potential applications of molecular epidemiological tools and methods toward malaria control and elimination efforts.Citation to related work
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