Population Genetics, Evolutionary Genomics, and Genome-Wide Studies of Malaria: A View Across the International Centers of Excellence for Malaria Research
Genre
Journal ArticleDate
2015-09-01Author
Carlton, JMVolkman, SK
Uplekar, S
Hupalo, DN
Pereira Alves, JM
Cui, L
Donnelly, M
Roos, DS
Harb, OS
Acosta, M
Read, A
Ribolla, PEM
Singh, OP
Valecha, N
Wassmer, SC
Ferreira, M
Escalante, AA
Subject
AnimalsAnopheles
Genetic Markers
Genetics, Population
Genome-Wide Association Study
Genotyping Techniques
Humans
International Cooperation
Malaria
Microsatellite Repeats
Plasmodium
Plasmodium falciparum
Plasmodium vivax
Sequence Analysis, DNA
Permanent link to this record
http://hdl.handle.net/20.500.12613/5205
Metadata
Show full item recordDOI
10.4269/ajtmh.15-0049Abstract
© The American Society of Tropical Medicine and Hygiene. The study of the three protagonists in malaria-the Plasmodium parasite, the Anopheles mosquito, and the human host-is key to developing methods to control and eventually eliminate the disease. Genomic technologies, including the recent development of next-generation sequencing, enable interrogation of this triangle to an unprecedented level of scrutiny, and promise exciting progress toward real-time epidemiology studies and the study of evolutionary adaptation. We discuss the use of genomics by the International Centers of Excellence for Malaria Research, a network of field sites and laboratories in malaria-endemic countries that undertake cutting-edge research, training, and technology transfer in malarious countries of the world.Citation to related work
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http://dx.doi.org/10.34944/dspace/5187