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dc.creatorBlair, JE
dc.creatorIkeo, K
dc.creatorGojobori, T
dc.creatorBlair Hedges, S
dc.date.accessioned2021-01-28T20:28:04Z
dc.date.available2021-01-28T20:28:04Z
dc.date.issued2002-04-08
dc.identifier.issn1471-2148
dc.identifier.issn1471-2148
dc.identifier.doihttp://dx.doi.org/10.34944/dspace/5068
dc.identifier.other11985779 (pubmed)
dc.identifier.urihttp://hdl.handle.net/20.500.12613/5086
dc.description.abstractBackground: The complete genomes of three animals have been sequenced by global research efforts: a nematode worm (Caenorhabditis elegans), an insect (Drosophila melanogaster), and a vertebrate (Homo sapiens). Remarkably, their relationships have yet to be clarified. The confusion concerns the enigmatic position of nematodes. Traditionally, nematodes have occupied a basal position, in part because they lack a true body cavity. However, the leading hypothesis now joins nematodes with arthropods in a molting clade, Ecdysozoa, based on data from several genes. Results: We tested the Ecdysozoa hypothesis with analyses of more than 100 nuclear protein alignments, under conditions that would expose biases, and found that it was not supported. Instead, we found significant support for the traditional hypothesis, Coelomata. Our result is robust to different rates of sequence change among genes and lineages, different numbers of taxa, and different species of nematodes. Conclusion: We conclude that insects (arthropods) are genetically and evolutionarily closer to humans than to nematode worms. © 2002 Blair et al; licensee BioMed Central Ltd.
dc.format.extent7-
dc.language.isoeng
dc.relation.haspartBMC Evolutionary Biology
dc.relation.isreferencedbySpringer Science and Business Media LLC
dc.subjectAnimals
dc.subjectBias
dc.subjectCaenorhabditis elegans
dc.subjectDrosophila melanogaster
dc.subjectEvolution, Molecular
dc.subjectHumans
dc.subjectModels, Biological
dc.subjectMutation
dc.subjectNuclear Proteins
dc.subjectPhylogeny
dc.titleThe evolutionary position of nematodes
dc.typeArticle
dc.type.genreJournal Article
dc.relation.doi10.1186/1471-2148-2-7
dc.ada.noteFor Americans with Disabilities Act (ADA) accommodation, including help with reading this content, please contact scholarshare@temple.edu
dc.date.updated2021-01-28T20:28:01Z
refterms.dateFOA2021-01-28T20:28:04Z


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