• Madhyamaka in Tibet: Thinking Through the Ultimate Truth

      Duckworth, Douglas S. (2016)
      본고는 티벳 중관 사상의 지배적인 해석적 줄기를 철학적으로 재구축한다. 논자는 마크 시더리츠(Mark Siderits)가 용수의 중관에 대한 관점으로 특징 지 은 것, 특히 시더리츠가 용수에 대해 주장한 것처럼 궁극적인 진리는 논리를 여읜 것이라는 관점과 중관에 대한 티벳 중관학의 해석의 특징들을 구별한다. 그러한 과정에서 논자는 중관학파가 유가행파와 양립한다는 해석에 대하여 미 팜(1846-1912)이 제시한 해석에 주목하여 입증한다. 미팜의 이론은 진제와 속 제의 언설불가능한 통합에 대해 설명함으로써 중관학파와 유가행파의 교각역 할을 한다. 논자는 모든 진리를 틀에 의지하는 것(framework-dependent)으로서 이해 하는 해석 체계로서의 중관학파에 주목함으로써 불가해한 진리가 유가행파 및 중관학파와 양립가능하다는 것을 주장한다. 즉, 모든 진리가 중관학파의 특수 한 틀과 관계되며, 틀에 의지하는 진리는 항상 관습적인 것 또는 상대적인 진 리들일 뿐이며 틀에 의지하지 않는 진리는 존재하지 않는 것이다. 그러나 그러 한 틀의 구조 자체는 생각과 표현의 범위를 넘어서는, 즉 “틀에 규정될 수 없는 것(unframeable)” 것인데, 왜냐하면 개별적 진리는 필수적으로 어떤 특수한 틀 안에 가둬지기 때문이다. 틀의 경계를 초월하고 완전히 틀 안에 가둬질 수 없는 것이 바로 궁극적 진리이다. 한편 공(空)은 중관학파에서 궁극적 진리에 관한 핵심적 은유이며, 언설 불 가능한 (틀을 벗어난) 궁극성은 유가행파에서 “의타기”(paratantra)와 “알라 야식”(ālayavijñāna)과 같이 다른 방식들로 나타난다. 불가해한 궁극성은 물 론 유가행파에서도 유지되지만 중관학파의 해석과 갈등을 일으킬 필요는 없었 다. 이는 일체가 공이기 때문이며, 또한 연기에 의한 것이기 때문(이고, 공이 공한 것과 마찬가지로 연기 역시 의존적이기 때문)이다.
    • Magnetic control of ultra-cold <sup>6</sup>Li and <sup>174</sup>Yb(<sup>3</sup>P<inf>2</inf>) atom mixtures with Feshbach resonances

      Petrov, A; Makrides, C; Kotochigova, S (2015-04-01)
      © 2015 IOP Publishing Ltd and Deutsche Physikalische Gesellschaft. We theoretically evaluate the feasibility to form magnetically-tunable Feshbach molecules in collisions between fermionic 6Li atoms and bosonic metastable 174Yb(3P2) atoms. In contrast to the well-studied alkali-metal atom collisions, collisions with meta-stable atoms are highly anisotropic. Our first-principle coupled-channel calculation of these collisions reveals the existence of broad Feshbach resonances due to the combined effect of anisotropic-molecular and atomic-hyperfine interactions. In order to fit our predictions to the specific positions of experimentally-observed broad resonance structures (Dowd et al 2014) we optimized the shape of the short-range potentials by direct least-square fitting. This allowed us to identify the dominant resonance by its leading angular momentum quantum numbers and describe the role of collisional anisotropy in the creation and broadening of this and other resonances.
    • Magnetic field dependent interactions in an ultracold Li-Yb(<sup>3</sup>P<inf>2</inf>) mixture

      Dowd, W; Roy, RJ; Shrestha, RK; Petrov, A; Makrides, C; Kotochigova, S; Gupta, S (2015-05-01)
      © 2015 IOP Publishing Ltd and Deutsche Physikalische Gesellschaft. Magnetic Feshbach resonances have allowed great success in the production of ultracold diatomic molecules from bi-alkali mixtures, but have so far eluded observation in mixtures of alkali and alkaline-earth-like atoms. Inelastic collisional properties of ultracold atomic systems exhibit resonant behavior in the vicinity of such resonances, providing a detection signature. We study magnetic field dependent inelastic effects via atom loss spectroscopy in an ultracold heteronuclear mixture of alkali 6Li in the ground state and alkaline-earth-like 174Yb in an excited electronic metastable state (3P2, mJ = -1). We observe a variation of the interspecies inelastic two-body rate coefficient by nearly one order of magnitude over a 100-520 G magnetic field range. By comparing to ab initio calculations we link our observations to interspecies Feshbach resonances arising from anisotropic interactions in this novel collisional system.
    • Maintenance Versus Transmission Deficits: The Effect of Delay on Naming Performance in Aphasia

      Martin, N; Dell, GS (2019-11-27)
      © Copyright © 2019 Martin and Dell. We propose that deficits in lexical retrieval can involve difficulty in transmission of activation between processing levels, or difficulty in maintaining activation. In support, we present an investigation of picture naming by persons with aphasia in which the naming response is generated after a 1 s (sec) cue to respond in one condition or a 5 s cue to respond in another. Some individuals did better after 5 s, some did worse after 5 s, and some were not impacted by the delay. It is suggested that better performance after 5 s indicates a transmission deficit and that worse performance after 5 s indicates a maintenance deficit. To support this hypothesis, we adapted the two-step semantic-phonological model of lexical retrieval (Schwartz et al., 2006) so that it can simulate the passage of time and can simulate lesions in transmission (its semantic and phonological connection strength parameters) and/or maintenance (its decay parameter). The naming error patterns after 1 and 5 s for each participant were successfully fit to the model. Persons who did better after 5 s were found to have low connection strength parameters, persons who did worse after 5 s were simulated with an increased decay rate, and persons whose performance did not differ with delay were found to have lesions of both types. Some potential theoretical and clinical implications are discussed.
    • Make and Let Die: Untimely Sovereignties

      Joy, Eileen A. (2016-03-10)
      This collection of essays by one of medieval studies’ most brilliant historians argues that the analysis and critique of biopower, as conventionally defined by Michel Foucault and then widely assumed in much contemporary theory of sovereignty, is a sovereign mode of temporalization caught up in the very time-machine it ostensibly seeks to expose and dismantle. For Michel Foucault, biopower (epitomized in his maxim “to make live and to let die”) is the defining sign of the modern, and he famously argued that the task of political philosophy was to cut off the head of the classical (premodern) sovereign, the one “who made die and let live.” Entrapped by his supersessionary thinking on the question, Foucault argued that the maxim of “to make live and let die” of modern sovereignty superseded a premodern sovereignty characterized by the contrasting power “to make die and let live.” The essays collected in Biddick’s book (some reprinted and some published here for the first time) argue that Foucault spoke too soon about the supposed “then” of the classical sovereign and the modern “now,” and this became painfully apparent in his analysis of Nazism in his later lectures, Society Must be Defended. There Foucault groped to articulate an anguishing paradox: How could it be that the Nazis, as the ultimate biopolitical sovereign machine, would insist on an archaic (premodern) mode of sovereignty in their death camps? Here is how he posed the question in that lecture: “How can the power of death, the function of death, be exercised in a political system centered upon biopower?” Foucault left this question hanging.
    • Malaria in pregnancy: A passive surveillance study of pregnant women in low transmission areas of Colombia, Latin America

      Lopez-Perez, M; Pacheco, MA; Buriticá, L; Escalante, AA; Herrera, S; Arévalo-Herrera, M (2016-02-05)
      © 2016 Lopez-Perez et al. Background: Malaria causes a significant burden in highly endemic areas where children and pregnant women are more susceptible to severe disease and death, however, in low transmission settings malaria in pregnant women is less frequent. The aim of this study was to provide information of clinical profile, anti-parasite host immune responses and parasite genotyping of pregnant women with malaria in low endemic areas of Colombia. Methods: This was a descriptive study conducted through passive surveillance in 1328 individuals from three endemic areas of Córdoba, Nariño and Chocó departments between 2011 and 2013. Trained physicians confirmed the pregnancy status and recorded clinical and epidemiological information. Haematological parameters, as well as hepatic and renal function, anti-malarial antibodies and parasite genotypes were evaluated. Results: A total of 582 women presented with malaria infection, 34 of whom were pregnant (5.8 %), and most were infected by Plasmodium falciparum (n = 24). In 44 % (n = 15) of the women, the infection occurred during the first half of pregnancy. Although uncomplicated disease and parasitaemia ≤20,000 parasites/μL were common (n = 31), three women (8.8 %) infected by P. falciparum were classified as severe cases. Mild to moderate anaemia (68 %) and mild thrombocytopaenia (41 %) were the most frequent blood alterations and in four women acute renal failure was observed. Six women presented a second malaria episode during pregnancy mainly caused by P. vivax (n = 5), although no direct evidence of relapse was found by genotyping. Two out of the six women presenting a second malaria episode had severe malaria. A low prevalence of specific anti-parasite antibodies was found. Microsatellites indicated that all P. vivax infections involved multiple lineages whereas all but one P. falciparum infections harboured single genotypes. Conclusions: Most malaria infected pregnant women displayed uncomplicated malaria, although a few of them with a second malaria episode presented an increased risk of severe malaria which appeared to be associated with malaria transmission intensity and not with levels of anti-parasite antibodies. The effects of severe malaria in both mother and fetus warrant future studies in low transmission settings. Keywords: Malaria, Pregnancy, Colombia, Plasmodium, Antibodies, Microsatellite repeats.
    • Malaria Molecular Epidemiology: Lessons from the International Centers of Excellence for Malaria Research Network

      Escalante, AA; Ferreira, MU; Vinetz, JM; Volkman, SK; Cui, L; Gamboa, D; Krogstad, DJ; Barry, AE; Carlton, JM; van Eijk, AMA; Pradhan, K; Mueller, I; Greenhouse, B; Pacheco, MA; Vallejo, AF; Herrera, S; Felger, I (2015-09-01)
      © The American Society of Tropical Medicine and Hygiene. Molecular epidemiology leverages genetic information to study the risk factors that affect the frequency and distribution of malaria cases. This article describes molecular epidemiologic investigations currently being carried out by the International Centers of Excellence for Malaria Research (ICEMR) network in a variety of malaria-endemic settings. First, we discuss various novel approaches to understand malaria incidence and gametocytemia, focusing on Plasmodium falciparum and Plasmodium vivax. Second, we describe and compare different parasite genotyping methods commonly used in malaria epidemiology and population genetics. Finally, we discuss potential applications of molecular epidemiological tools and methods toward malaria control and elimination efforts.
    • Mammalian microRNAs: A small world for fine-tuning gene expression

      Sevignani, C; Calin, GA; Siracusa, LD; Croce, CM (2006-03-01)
      The basis of eukaryotic complexity is an intricate genetic architecture where parallel systems are involved in tuning gene expression, via RNA-DNA, RNA-RNA, RNA-protein, and DNA-protein interactions. In higher organisms, about 97% of the transcriptional output is represented by noncoding RNA (ncRNA) encompassing not only rRNA, tRNA, introns, 5′ and 3′ untranslated regions, transposable elements, and intergenic regions, but also a large, rapidly emerging family named microRNAs. MicroRNAs are short 20-22-nucleotide RNA molecules that have been shown to regulate the expression of other genes in a variety of eukaryotic systems. MicroRNAs are formed from larger transcripts that fold to produce hairpin structures and serve as substrates for the cytoplasmic Dicer, a member of the RNase III enzyme family. A recent analysis of the genomic location of human microRNA genes suggested that 50% of microRNA genes are located in cancer-associated genomic regions or in fragile sites. This review focuses on the possible implications of microRNAs in post-transcriptional gene regulation in mammalian diseases, with particular focus on cancer. We argue that developing mouse models for deleted and/or overexpressed microRNAs will be of invaluable interest to decipher the regulatory networks where microRNAs are involved. © Springer Science+Business Media, Inc. 2006.
    • Management of Chlamydia trachomatis genital tract infection: Screening and treatment challenges

      Taylor, BD; Haggerty, CL; Taylor, Brandie|0000-0002-8234-1815 (2011-03-21)
      Chlamydia trachomatis is a prevalent sexually transmitted infection that can lead to serious reproductive morbidity. Management and control of C. trachomatis is a challenge, largely due to its asymptomatic nature and our incomplete understanding of its natural history. Although chlamydia screening programs have been implemented worldwide, several countries have observed increasing rates of reported chlamydia cases. We reviewed the literature relating to the long-term complications of C. trachomatis, as well as screening strategies, treatment, and prevention strategies for reducing chlamydia in the population. Articles from 1950-2010 were identified through a Medline search using the keyword "Chlamydia trachomatis" combined with "screening", "pelvic inflammatory disease", "endometritis", "salpingitis", "infertility", "ectopic pregnancy", "urethritis", "epididymitis", "proctitis", "prostatitis", "reinfection", "cost- effectiveness", "treatment", "vaccines", or "prevention". Progression of C. trachomatis varies, and recurrent infections are common. Currently, there is limited evidence on the effectiveness of chlamydia screening. Higher quality studies are needed to determine the efficacy of more frequent screening, on a broader range of sequelae, including infertility and ectopic pregnancy, in addition to pelvic inflammatory disease. Studies should focus on delineating the natural history of recurrent infections, paying particular attention to treatment failures. Furthermore, alternatives to screening, such as vaccines, should continue to be explored. © 2011 Taylor and Haggerty, publisher and licensee Dove Medical Press Ltd.
    • Mapping dynamic histone acetylation patterns to gene expression in nanog-depleted murine embryonic stem cells

      Markowetz, F; Mulder, KW; Airoldi, EM; Lemischka, IR; Troyanskaya, OG; Airoldi, Edoardo|0000-0002-3512-0542 (2010-12-01)
      Embryonic stem cells (ESC) have the potential to self-renew indefinitely and to differentiate into any of the three germ layers. The molecular mechanisms for self-renewal, maintenance of pluripotency and lineage specification are poorly understood, but recent results point to a key role for epigenetic mechanisms. In this study, we focus on quantifying the impact of histone 3 acetylation (H3K9,14ac) on gene expression in murine embryonic stem cells. We analyze genome-wide histone acetylation patterns and gene expression profiles measured over the first five days of cell differentiation triggered by silencing Nanog, a key transcription factor in ESC regulation. We explore the temporal and spatial dynamics of histone acetylation data and its correlation with gene expression using supervised and unsupervised statistical models. On a genome-wide scale, changes in acetylation are significantly correlated to changes in mRNA expression and, surprisingly, this coherence increases over time. We quantify the predictive power of histone acetylation for gene expression changes in a balanced cross-validation procedure. In an in-depth study we focus on genes central to the regulatory network of Mouse ESC, including those identified in a recent genome-wide RNAi screen and in the PluriNet, a computationally derived stem cell signature. We find that compared to the rest of the genome, ESC-specific genes show significantly more acetylation signal and a much stronger decrease in acetylation over time, which is often not reflected in a concordant expression change. These results shed light on the complexity of the relationship between histone acetylation and gene expression and are a step toward dissecting the multilayer regulatory mechanisms that determine stem cell fate. © 2010 Markowetz et al.
    • Maritime Paleoindian technology, subsistence, and ecology at an ~11,700 year old Paleocoastal site on California's Northern Channel Islands, USA

      Erlandson, JM; Braje, TJ; Ainis, AF; Culleton, BJ; Gill, KM; Hofman, CA; Kennett, DJ; Reeder-Myers, LA; Rick, TC (2020-09-01)
      Copyright: © This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication. During the last 10 years, we have learned a great deal about the potential for a coastal peopling of the Americas and the importance of marine resources in early economies. Despite research at a growing number of terminal Pleistocene archaeological sites on the Pacific Coast of the Americas, however, important questions remain about the lifeways of early Paleocoastal peoples. Research at CA-SRI-26, a roughly 11,700 year old site on California's Santa Rosa Island, provides new data on Paleoindian technologies, subsistence strategies, and seasonality in an insular maritime setting. Buried beneath approximately two meters of alluvium, much of the site has been lost to erosion, but its remnants have produced chipped stone artifacts (crescents and Channel Island Amol and Channel Island Barbed points) diagnostic of early island Paleocoastal components. The bones of waterfowl and seabirds, fish, and marine mammals, along with small amounts of shellfish document a diverse subsistence strategy. These data support a relatively brief occupation during the wetter “winter” season (late fall to early spring), in an upland location several km from the open coast. When placed in the context of other Paleocoastal sites on the Channel Islands, CA-SRI-26 demonstrates diverse maritime subsistence strategies and a mix of seasonal and more sustained year-round island occupations. Our results add to knowledge about a distinctive island Paleocoastal culture that appears to be related to Western Stemmed Tradition sites widely scattered across western North America.
    • Market model for resource allocation in emerging sensor networks with reinforcement learning

      Zhang, Y; Song, B; Zhang, Y; Du, X; Guizani, M; Du, Xiaojiang|0000-0003-4235-9671 (2016-12-01)
      © 2016 by the authors; licensee MDPI, Basel, Switzerland. Emerging sensor networks (ESNs) are an inevitable trend with the development of the Internet of Things (IoT), and intend to connect almost every intelligent device. Therefore, it is critical to study resource allocation in such an environment, due to the concern of efficiency, especially when resources are limited. By viewing ESNs as multi-agent environments, we model them with an agent-based modelling (ABM) method and deal with resource allocation problems with market models, after describing users’ patterns. Reinforcement learning methods are introduced to estimate users’ patterns and verify the outcomes in our market models. Experimental results show the efficiency of our methods, which are also capable of guiding topology management.
    • Markov models of the apo-MDM2 lid region reveal diffuse yet two-state binding dynamics and receptor poses for computational docking

      Mukherjee, S; Pantelopulos, GA; Voelz, VA; Voelz, Vincent|0000-0002-1054-2124 (2016-08-19)
      © The Author(s) 2016. MDM2 is a negative regulator of p53 activity and an important target for cancer therapeutics. The N-Terminal lid region of MDM2 modulates interactions with p53 via competition for its binding cleft, exchanging slowly between docked and undocked conformations in the absence of p53. To better understand these dynamics, we constructed Markov State Models (MSMs) from large collections of unbiased simulation trajectories of apo-MDM2, and find strong evidence for diffuse, yet two-state folding and binding of the N-Terminal region to the p53 receptor site. The MSM also identifies holo-like receptor conformations highly suitable for computational docking, despite initiating trajectories from closed-cleft receptor structures unsuitable for docking. Fixed-Anchor docking studies using a test set of high-Affinity small molecules and peptides show simulated receptor ensembles achieve docking successes comparable to cross-docking studies using crystal structures of receptors bound by alternative ligands. For p53, the best-scoring receptor structures have the N-Terminal region lid region bound in a helical conformation mimicking the bound structure of p53, suggesting lid region association induces receptor conformations suitable for binding. These results suggest that MD + MSM approaches can sample binding-competent receptor conformations suitable for computational peptidomimetic design, and that inclusion of disordered regions may be essential to capturing the correct receptor dynamics.
    • Mass sum rules of the electron in quantum electrodynamics

      Rodini, S; Metz, A; Pasquini, B (2020-09-01)
      © 2020, The Author(s). Different decompositions of the nucleon mass, in terms of the masses and energies of the underlying constituents, have been proposed in the literature. We explore the corresponding sum rules in quantum electrodynamics for an electron at one-loop order in perturbation theory. To this aim we compute the form factors of the energy-momentum tensor, by paying particular attention to the renormalization of ultraviolet divergences, operator mixing and scheme dependence. We clarify the expressions of all the proposed sum rules in the electron rest frame in terms of renormalized operators. Furthermore, we consider the same sum rules in a moving frame, where they become energy decompositions. Finally, we discuss some implications of our study on the mass sum rules for the nucleon.
    • Maternal behaviors during pregnancy impact offspring obesity risk

      Phelan, S; Hart, C; Phipps, M; Abrams, B; Schaffner, A; Adams, A; Wing, R (2011-12-01)
      This study investigated the effects of maternal changes during pregnancy in diet, exercise, and psychosocial factors on offspring weight parameters at birth and 6 months. In overweight/obese (OW/OB; n = 132) mothers, greater % kcal from sweets early in pregnancy was the strongest, independent predictor of higher weight for age (WFA) (beta = 0. 19; P = 0. 004), higher odds of macrosomia (OR = 1.1 (1.01.2); P = 0. 004) andWFA 90th percentile at birth (OR = 1.2 (1.11.3); P = 0. 002) and higher WFA at 6 months (beta = 0. 30; P = 0. 002). In normal weight (n = 153) mothers, higher intake of soft drinks was the strongest predictor of higher offspring WFA at birth (beta = 0.16; P = 0. 04) but not at 6 months. Prenatal physical activity, depressive symptoms, and sleep-related variables did not significantly predict offspring weight outcomes. Mothers eating behaviors during pregnancy, especially intake of sweets in OW/OB mothers, may have a lasting effect on child weight. Copyright © 2011 Suzanne Phelan et al.
    • Maternal depression attenuates newborn vitamin D concentrations in winter-spring: a prospective population-based study

      Zhou, Qi-fan; Zhang, Meng-xiao; Tong, Shi-lu; Tao, Rui-xue; Hao, Jia-hu; Huang, Kun; Tao, Fang-biao; Zhu, Peng; Tao, Rongjia|0000-0001-5058-4401 (2017-05-08)
      We aimed to investigate whether the newborns of mothers with maternal depression (MD) had lower vitamin D levels than newborns of non-MD (NMD) mothers and identify the potential mechanism underlying this association. Maternal depressive symptoms in late pregnancy and concentrations of cord blood 25 hydroxyvitamin D (25(OH)D) were measured in 1491 mother-infant pairs. Data on maternal sociodemographic characteristics, health status, lifestyle and birth outcomes were prospectively collected. For infants born in winter-spring, the infants of MD mothers had significantly reduced concentrations of 25(OH) D (adjusted β = -3.51 nmol/L; 95% CI: -6.19, -0.84; P = 0.010) and lower birth weight (3267 ± 470 g vs 3348 ± 598 g, F = 4.64, P = 0.031), compared with the infants of NMD mothers. A significant, inverse linear relationship was noted between maternal depression scores and the concentration of 25(OH)D for infants born in winter-spring (adjusted β = -0.158; 95% CI: -0.259, -0.057). The significant, inverse linear relationship between maternal depression scores and fetomaternal ratios of 25(OH) D was also observed among the infants born in winter-spring (adjusted β = -0.005; 95% CI: -0.008, -0.003). MD appears to significantly attenuate the vitamin D concentrations and birth weight of infants born in winter-spring. A decreased fetomaternal ratio of 25(OH)D might be involved in this biological pathway.
    • MBE Emerging Classics 2021

      Rowe, H; Kumar, S; Kumar, Sudhir|0000-0002-9918-8212 (2021-01-04)
    • MBE Transitions to the Open Access Publication Model in 2021

      Kumar, S; Rowe, H; Kumar, Sudhir|0000-0002-9918-8212 (2020-12-16)
      © The Author(s) 2020. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. From the first day of 2021, all manuscripts published in the journal Molecular Biology and Evolution (MBE) will be freely accessible online without a subscription. This exciting change will make all the MBE content available to all readers immediately upon publication.
    • Measurement of double-polarization asymmetries in the quasi-elastic He→3(e→,e<sup>′</sup>p) process

      Mihovilovič, M; Jin, G; Long, E; Zhang, YW; Allada, K; Anderson, B; Annand, JRM; Averett, T; Bertozzi, W; Boeglin, W; Bradshaw, P; Camsonne, A; Canan, M; Cates, GD; Chen, C; Chen, JP; Chudakov, E; De Leo, R; Deng, X; Deltuva, A; Deur, A; Dutta, C; El Fassi, L; Flay, D; Frullani, S; Garibaldi, F; Gao, H; Gilad, S; Gilman, R; Glamazdin, O; Golak, J; Golge, S; Gomez, J; Hansen, O; Higinbotham, DW; Holmstrom, T; Huang, J; Ibrahim, H; de Jager, CW; Jensen, E; Jiang, X; Jones, M; Kamada, H; Kang, H; Katich, J; Khanal, HP; Kievsky, A; King, P; Korsch, W; LeRose, J; Lindgren, R; Lu, HJ; Luo, W; Marcucci, LE; Markowitz, P; Meziane, M; Michaels, R; Moffit, B; Monaghan, P; Muangma, N; Nanda, S; Norum, BE; Pan, K; Parno, DS; Piasetzky, E; Posik, M; Punjabi, V; Puckett, AJR; Qian, X; Qiang, Y; Qui, X; Riordan, S; Saha, A; Sauer, PU; Sawatzky, B; Schiavilla, R; Schoenrock, B; Shabestari, M; Shahinyan, A; Širca, S; Skibiński, R; St. John, J; Subedi, R; Sulkosky, V; Tireman, W; Tobias, WA; Topolnicki, K; Urciuoli, GM; Viviani, M; Wang, D; Wang, K; Wang, Y; Watson, J; Wojtsekhowski, B; Witała, H; Ye, Z; Zhan, X; Zhang, Y; Zheng, X; Zhao, B (2019-01-10)
      © 2018 The Author We report on a precise measurement of double-polarization asymmetries in electron-induced breakup of He3 proceeding to pd and ppn final states, performed in quasi-elastic kinematics at Q2=0.25(GeV/c)2 for missing momenta up to 250MeV/c. These observables represent highly sensitive tools to investigate the electromagnetic and spin structure of He3 and the relative importance of two- and three-body effects involved in the breakup reaction dynamics. The measured asymmetries cannot be satisfactorily reproduced by state-of-the-art calculations of He3 unless their three-body segment is adjusted, indicating that the spin-dependent part of the nuclear interaction governing the three-body breakup process is much smaller than previously thought.