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dc.creatorNgo, CT
dc.creatorAlm, KH
dc.creatorMetoki, A
dc.creatorHampton, W
dc.creatorRiggins, T
dc.creatorNewcombe, NS
dc.creatorOlson, IR
dc.date.accessioned2021-01-22T14:31:53Z
dc.date.available2021-01-22T14:31:53Z
dc.date.issued2017-12-01
dc.identifier.issn1878-9293
dc.identifier.issn1878-9307
dc.identifier.doihttp://dx.doi.org/10.34944/dspace/4826
dc.identifier.other29175538 (pubmed)
dc.identifier.urihttp://hdl.handle.net/20.500.12613/4844
dc.description.abstract© 2017 The Authors Episodic memory undergoes dramatic improvement in early childhood; the reason for this is poorly understood. In adults, episodic memory relies on a distributed neural network. Key brain regions that supporting these processes include the hippocampus, portions of the parietal cortex, and portions of prefrontal cortex, each of which shows different developmental profiles. Here we asked whether developmental differences in the axonal pathways connecting these regions may account for the robust gains in episodic memory in young children. Using diffusion weighted imaging, we examined whether white matter connectivity between brain regions implicated in episodic memory differed with age, and were associated with memory performance differences in 4- and 6-year-old children. Results revealed that white matter connecting the hippocampus to the inferior parietal lobule significantly predicted children's performance on episodic memory tasks. In contrast, variation in the white matter connecting the hippocampus to the medial prefrontal cortex did not relate to memory performance. These findings suggest that structural connectivity between the hippocampus and lateral parietal regions is relevant to the development of episodic memory.
dc.format.extent41-53
dc.language.isoen
dc.relation.haspartDevelopmental Cognitive Neuroscience
dc.relation.isreferencedbyElsevier BV
dc.rightsCC BY-NC-ND
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectWhite matter
dc.subjectMemory development
dc.subjectEpisodic memory
dc.subjectDiffusion weighted imaging
dc.titleWhite matter structural connectivity and episodic memory in early childhood
dc.typeArticle
dc.type.genreJournal Article
dc.relation.doi10.1016/j.dcn.2017.11.001
dc.ada.noteFor Americans with Disabilities Act (ADA) accommodation, including help with reading this content, please contact scholarshare@temple.edu
dc.date.updated2021-01-22T14:31:49Z
refterms.dateFOA2021-01-22T14:31:54Z


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