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dc.creatorRodrigues, PT
dc.creatorValdivia, HO
dc.creatorDe Oliveira, TC
dc.creatorAlves, JMP
dc.creatorDuarte, AMRC
dc.creatorCerutti-Junior, C
dc.creatorBuery, JC
dc.creatorBrito, CFA
dc.creatorDe Souza, JC
dc.creatorHirano, ZMB
dc.creatorBueno, MG
dc.creatorCatão-Dias, JL
dc.creatorMalafronte, RS
dc.creatorLadeia-Andrade, S
dc.creatorMita, T
dc.creatorSantamaria, AM
dc.creatorCalzada, JE
dc.creatorTantular, IS
dc.creatorKawamoto, F
dc.creatorRaijmakers, LRJ
dc.creatorMueller, I
dc.creatorPacheco, MA
dc.creatorEscalante, AA
dc.creatorFelger, I
dc.creatorFerreira, MU
dc.date.accessioned2021-01-21T15:01:21Z
dc.date.available2021-01-21T15:01:21Z
dc.date.issued2018-12-01
dc.identifier.issn2045-2322
dc.identifier.issn2045-2322
dc.identifier.doihttp://dx.doi.org/10.34944/dspace/4781
dc.identifier.other29386521 (pubmed)
dc.identifier.urihttp://hdl.handle.net/20.500.12613/4799
dc.description.abstract© 2018 The Author(s). We examined the mitogenomes of a large global collection of human malaria parasites to explore how and when Plasmodium falciparum and P. vivax entered the Americas. We found evidence of a significant contribution of African and South Asian lineages to present-day New World malaria parasites with additional P. vivax lineages appearing to originate from Melanesia that were putatively carried by the Australasian peoples who contributed genes to Native Americans. Importantly, mitochondrial lineages of the P. vivax-like species P. simium are shared by platyrrhine monkeys and humans in the Atlantic Forest ecosystem, but not across the Amazon, which most likely resulted from one or a few recent human-to-monkey transfers. While enslaved Africans were likely the main carriers of P. falciparum mitochondrial lineages into the Americas after the conquest, additional parasites carried by Australasian peoples in pre-Columbian times may have contributed to the extensive diversity of extant local populations of P. vivax.
dc.format.extent1993-
dc.language.isoen
dc.relation.haspartScientific Reports
dc.relation.isreferencedbySpringer Science and Business Media LLC
dc.rightsCC BY
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectAnimals
dc.subjectContinental Population Groups
dc.subjectDisease Transmission, Infectious
dc.subjectGenome, Mitochondrial
dc.subjectHaplorhini
dc.subjectHuman Migration
dc.subjectHumans
dc.subjectMalaria, Falciparum
dc.subjectPhylogeny
dc.subjectPlasmodium falciparum
dc.titleHuman migration and the spread of malaria parasites to the New World
dc.typeArticle
dc.type.genreJournal Article
dc.relation.doi10.1038/s41598-018-19554-0
dc.ada.noteFor Americans with Disabilities Act (ADA) accommodation, including help with reading this content, please contact scholarshare@temple.edu
dc.date.updated2021-01-21T15:01:17Z
refterms.dateFOA2021-01-21T15:01:21Z


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