11-Step Total Synthesis of Pallambins C and D
dc.creator | Martinez, LP | |
dc.creator | Umemiya, S | |
dc.creator | Wengryniuk, SE | |
dc.creator | Baran, PS | |
dc.date.accessioned | 2020-12-08T21:38:43Z | |
dc.date.available | 2020-12-08T21:38:43Z | |
dc.date.issued | 2016-06-22 | |
dc.identifier.issn | 0002-7863 | |
dc.identifier.issn | 1520-5126 | |
dc.identifier.doi | http://dx.doi.org/10.34944/dspace/4173 | |
dc.identifier.other | 27284962 (pubmed) | |
dc.identifier.uri | http://hdl.handle.net/20.500.12613/4191 | |
dc.description.abstract | © 2016 American Chemical Society. The structurally intriguing terpenes pallambins C and D have been assembled in only 11 steps from a cheap commodity chemical: furfuryl alcohol. This synthesis, which features a redox-economic approach free of protecting-group manipulations, assembles all four-ring systems via a sequential cyclization strategy. Of these four-ring constructing operations, two are classical (Robinson annulation and Mukaiyama aldol) and two are newly devised. During the course of this work a method for the difunctionalization of enol ethers was developed, and the scope of this transformation was explored. | |
dc.format.extent | 7536-7539 | |
dc.language.iso | en | |
dc.relation.haspart | Journal of the American Chemical Society | |
dc.relation.isreferencedby | American Chemical Society (ACS) | |
dc.subject | Chemistry Techniques, Synthetic | |
dc.subject | Diterpenes | |
dc.subject | Furans | |
dc.subject | Molecular Structure | |
dc.subject | Oxidation-Reduction | |
dc.title | 11-Step Total Synthesis of Pallambins C and D | |
dc.type | Article | |
dc.type.genre | Journal Article | |
dc.relation.doi | 10.1021/jacs.6b04816 | |
dc.ada.note | For Americans with Disabilities Act (ADA) accommodation, including help with reading this content, please contact scholarshare@temple.edu | |
dc.date.updated | 2020-12-08T21:38:39Z | |
refterms.dateFOA | 2020-12-08T21:38:43Z |