Show simple item record

dc.contributor.advisorVarnum, Susan A.
dc.creatorWei, Guoxiu
dc.date.accessioned2020-11-05T19:50:37Z
dc.date.available2020-11-05T19:50:37Z
dc.date.issued2015
dc.identifier.other958156823
dc.identifier.urihttp://hdl.handle.net/20.500.12613/4025
dc.description.abstractHypertension is a chronic medical condition, and a primary contributor to severe cardiovascular disease. It can increase mortality risk. Studies have found that a low-grade inflammation is involved in the development of hypertension. In addition, men have been found to have a higher risk of hypertension than age-matched women, while women have an increased risk of hypertension after menopause. Female sex hormones are considered to play a protective role in the development and progression of hypertension. Prostanoids are inflammatory mediators, and have important physiological roles on promoting or suppressing inflammation. Studying the combined roles of these two biochemical families in disease development will be helpful to understand the balance between a self-protective effect and inflammatory response in hypertension, and find effective biomarkers to predict the progression of hypertension. In my study, a reversed phase high performance liquid chromatography is used to develop the
dc.format.extent177 pages
dc.language.isoeng
dc.publisherTemple University. Libraries
dc.relation.ispartofTheses and Dissertations
dc.rightsIN COPYRIGHT- This Rights Statement can be used for an Item that is in copyright. Using this statement implies that the organization making this Item available has determined that the Item is in copyright and either is the rights-holder, has obtained permission from the rights-holder(s) to make their Work(s) available, or makes the Item available under an exception or limitation to copyright (including Fair Use) that entitles it to make the Item available.
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/
dc.subjectChemistry
dc.subjectHypertension
dc.subjectProstanoids
dc.subjectQuantitative Structure-retention Relationship
dc.subjectSex Hormones
dc.titleEVALUATION OF THE COMBINATION OF PROSTANOIDS AND FEMALE SEX HORMONES AS INFLAMMATION BIOMARKERS AND THEIR IMPLICATION ON HYPERTENSION
dc.typeText
dc.type.genreThesis/Dissertation
dc.contributor.committeememberVarnum, Susan A.
dc.contributor.committeememberWunder, Stephanie L.
dc.contributor.committeememberZdilla, Michael J., 1978-
dc.contributor.committeememberShi, Justin Y.
dc.description.departmentChemistry
dc.relation.doihttp://dx.doi.org/10.34944/dspace/4007
dc.ada.noteFor Americans with Disabilities Act (ADA) accommodation, including help with reading this content, please contact scholarshare@temple.edu
dc.description.degreePh.D.
refterms.dateFOA2020-11-05T19:50:37Z


Files in this item

Thumbnail
Name:
TETDEDXWei-temple-0225E-12261.pdf
Size:
2.791Mb
Format:
PDF

This item appears in the following Collection(s)

Show simple item record