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    THE ANALYSIS OF EMDOGAIN BINDING AFFINITY FOR DIFFERENT PARTICULATE BONE GRAFT MATERIALS.

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    Genre
    Thesis/Dissertation
    Date
    2018
    Author
    Guba, Nina Marie
    Advisor
    Barbe, Mary F.
    Committee member
    Jefferies, Steven R.
    Albandar, Jasim M.
    Department
    Oral Biology
    Subject
    Dentistry
    Pacific Rim Studies
    Bone Graft
    Emdogain
    Protein Binding
    Permanent link to this record
    http://hdl.handle.net/20.500.12613/2961
    
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    DOI
    http://dx.doi.org/10.34944/dspace/2943
    Abstract
    Objectives: Traditional guided tissue regeneration procedures use particulate bone graft materials and occlusive membranes with the primary aim of reconstitution of the supporting periodontal tissues. Currently, the Food and Drug Administration has cleared only four treatment modalities for true periodontal regeneration. These materials are autogenous bone, demineralized freeze dried bone allograft, LANAP (Millennium Dental Technologies INC, Cerritos, CA) and Emdogain (Institut Straumann AG, Basel, Switzerland). The biologically inactive nature of many commercially available bone graft materials provides an opportunity for the addition of certain biologic materials to enhance the healing response. The development of an adequate carrier for biologic agents is a crucial step in the creation of a bioactive graft material. This experiment uses Emdogain (Institut Straumann AG, Basel, Switzerland) to study the specific characteristics of protein binding and release on three different commonl
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