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dc.creatorNakrani, Rima
dc.creatorYeung, Ho-Man
dc.creatorKim, Jin Sun
dc.creatorKamat, Bhishak
dc.creatorKumaran, Maruti
dc.date.accessioned2020-10-23T13:26:17Z
dc.date.available2020-10-23T13:26:17Z
dc.date.issued2020-10-05
dc.identifier.citationRima Nakrani, Ho-Man Yeung, Jin Sun Kim, Bhishak Kamat, Maruti Kumaran, "Pulmonary Artery Intimal Sarcoma: A Diagnostic Challenge Using a Multimodal Approach", Case Reports in Medicine, vol. 2020, Article ID 6795272, 4 pages, 2020. https://doi.org/10.1155/2020/6795272
dc.identifier.issn1687-9635
dc.identifier.doihttp://dx.doi.org/10.34944/dspace/1115
dc.identifier.urihttp://hdl.handle.net/20.500.12613/1133
dc.description.abstractPulmonary artery intimal sarcoma (PAIS) is a rare tumor without clear syndromic presentation other than nonspecific symptoms of cough, dyspnea, and weight loss. This diagnosis is difficult due to challenging radiographic interpretations of multiple imaging modalities. We present a case of a 60-year-old male, who presented to his pulmonologist and underwent a CT chest with IV contrast that initially suggested primary lung carcinoma. CT angiogram showed significant vascular filling defects suspicious of an intravascular mass, rather than vascular invasion by lung lesions. The PET/CT scans further suggested a malignant process, but indistinguishable between an extravascular or intravascular etiology. Taking these results together, they suggested an intravascular malignancy, prompting a tissue biopsy, which ultimately led to a diagnosis of PAIS with metastases. Establishing a definitive diagnosis is essential as treatment and prognosis are different for sarcoma compared to carcinoma. There is no standard treatment to date, and management often includes a multidisciplinary approach involving surgery, radiation, chemotherapy, and targeted therapy. PAIS is a rare entity that cannot be diagnosed clinically and needs a multimodality approach for its diagnosis.
dc.format.extent4 pages
dc.languageEnglish
dc.language.isoeng
dc.relation.ispartofOpen Access Publishing Fund
dc.relation.haspartCase Reports in Medicine, Vol. 2020, Article ID 6795272
dc.relation.isreferencedbyHindawi
dc.rightsAttribution CC BY
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.titlePulmonary Artery Intimal Sarcoma: A Diagnostic Challenge Using a Multimodal Approach
dc.typeText
dc.type.genreJournal article
dc.description.departmentMedicine
dc.relation.doihttps://doi.org/10.1155/2020/6795272
dc.ada.noteFor Americans with Disabilities Act (ADA) accommodation, including help with reading this content, please contact scholarshare@temple.edu
dc.description.schoolcollegeLewis Katz School of Medicine
dc.description.sponsorTemple University Libraries Open Access Publishing Fund, 2020-2021 (Philadelphia, Pa.)
dc.creator.orcid0000-0002-7188-9738
dc.temple.creatorNakrani, Rima
dc.temple.creatorYeung, Ho-Man
dc.temple.creatorKim, Jin Sun
dc.temple.creatorKamat, Bhishak
dc.temple.creatorKumaran, Maruti
refterms.dateFOA2020-10-23T13:26:17Z


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