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dc.creatorYeung, Ho-Man
dc.creatorGaffaney, Lauren
dc.date.accessioned2024-03-29T19:09:24Z
dc.date.available2024-03-29T19:09:24Z
dc.date.issued2022-12-09
dc.identifier.issn1687-9635
dc.identifier.urihttp://hdl.handle.net/20.500.12613/10077
dc.description.abstractBasilar predominant emphysema, or disproportionate emphysematous involvement of the lung bases compared to the apices, is an uncommon radiographic pattern of emphysema traditionally associated with alpha-1-antitrypsin deficiency (AATD). We present a case of a 59-year-old female with 41 pack-year tobacco use, Stage IV COPD with supplemental oxygen, and bibasilar predominant emphysema who successfully underwent bronchoscopic lung volume reduction. She presented with recurrent hospitalizations for frequent exacerbations. After lung reduction, the patient displayed improvement in functional status without hospitalizations at the 15-month follow-up. Careful history taking is essential for any patients diagnosed with lower lobe emphysema to elucidate the underlying etiology. This case challenges the notion that basilar emphysema is sensitive or specific for AATD and emphasizes that this pattern of emphysema has a broad differential diagnosis and alternative etiologies should be considered. Our patient was ultimately diagnosed with smoking-related emphysema, with atypical bibasilar involvement. Furthermore, basilar predominant emphysema should be considered a separate entity from its apical predominant counterpart.
dc.format.extent4 pages
dc.languageEnglish
dc.language.isoeng
dc.relation.ispartofFaculty/ Researcher Works
dc.relation.haspartCase Reports in Medicine, Vol. 2022
dc.relation.isreferencedbyHindawi
dc.rightsAttribution CC BY
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.titleBasilar Predominant Emphysema: Thinking beyond Alpha-1-Antitrypsin Deficiency
dc.typeText
dc.type.genreJournal article
dc.description.departmentMedicine
dc.relation.doihttp://dx.doi.org/10.1155/2022/9840085
dc.ada.noteFor Americans with Disabilities Act (ADA) accommodation, including help with reading this content, please contact scholarshare@temple.edu
dc.description.schoolcollegeLewis Katz School of Medicine
dc.creator.orcidYeung|0000-0002-7188-9738
dc.temple.creatorYeung, Ho-Man
dc.temple.creatorGaffaney, Lauren
refterms.dateFOA2024-03-29T19:09:24Z


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