• HACE1, a Novel Repressor of RAR Transcriptional Activity

      Soprano, Kenneth J.; Soprano, Dianne R.; Tsygankov, Alexander Y.; Long, Walter K. (Temple University. Libraries, 2009)
      The biological activities of retinoic acid (RA) and its synthetic analogues are mediated through nuclear receptors, termed retinoic acid receptors (RARs) and retinoid X receptors (RXRs). The transcriptional activity of RAR on target gene expression is achieved by its AF-1 domain and AF-2 domain. The function of AF-2 is known to be mediated by a number of coregulatory proteins. However the mechanism of AF-1 function is not well studied. We have hypothesized that the AF-1 function of RAR is regulated by specific interacting proteins. HACE1 was identified as an AF-1 domain interacting protein in a yeast two-hybrid screen. HACE1 interacts with RAR&beta<sub>3
    • Hadron Structure From Lattice Quantum Chromodynamics Using Twisted Mass Fermions

      Constantinou, Martha; Metz, Andreas; Sparveris, Nikolaos; Cichy, Krzysztof (Temple University. Libraries, 2021)
      Hadron structure is an important field in particle physics because hadrons make up most of the matter in nature. The theory of the strong nuclear force, via which the partons of hadrons interact, is Quantum Chromodynamics (QCD) and cannot be solved analytically. Lattice QCD (LQCD) is an ideal formulation of QCD and is the only formulation starting from first principles. In this thesis, we use LQCD for two primary topics of study: 1) nucleon structure and 2) pion and kaon structure. In the first study, we calculate the quark momentum fraction, helicity, and transversity for the nucleon. The calculations are performed on three ensembles at the physical point of the pion mass allowing us to study finite volume, discretization, strange and charm quark quenching, and excited-state systematic effects. Our calculations of the helicity and transversity are first predictions at the physical point. In the second study, we investigate pion and kaon structure. We calculate the first three non-trivial Mellin moments of the meson parton distribution functions (PDFs). For the kaon, this is the first direct calculation of the second and third moments. We carefully choose which matrix elements we implement so that there is no mixing with lower derivative operators, avoiding systematic uncertainties which are not well understood. We also perform an extensive study of the excited-state contamination. In a pioneering study, we show that the full x-dependence of the PDFs can be calculated from the first three Mellin moments. Such a calculation was previously thought to be unfeasible using moments calculated from LQCD. Our reconstruction of the PDFs allow us to comment on SU(3) flavor symmetry breaking and the high-x behavior of the pion PDF which are both interesting topics in hadron structure.
    • Haile Selassie and the Religious Field: Generative Structuralism and Christian Missions in Ethiopia

      Rey, Terry; Raines, John C. (Temple University. Libraries, 2010)
      With the momentum of previous Emperors, Haile Selassie steered Ethiopia on the path to modernization. One of his greatest obstacles was the Ethiopian Orthodox Church (EOC), which, being steeped in sixteen centuries of tradition, was accustomed to being the primary hegemonic power. Pierre Bourdieu's generative structuralism will be employed in this thesis to analyze the EOC's symbolic power as well as Selassie's efforts to dispossess the Church of its cultural power and make it an arm of the state. Controlling the rural periphery of Ethiopia, however meant introducing the basic structures of modernity to ethnic groups who had historically resisted Selassie's Amharic culture. Selassie permitted foreign missions, such as the Sudan Interior Mission (SIM) and Swedish Evangelical Mission (SEM), to function as his subcontractors for civilization by building schools, establishing medical stations, and evangelizing the non-Orthodox populations. Selassie failed to anticipate how mission structures contributed to the formation of resistant identities for Maale and Oromo converts. In analyzing these processes, the thesis also employs Robin Horton's theory of conversion while refuting Horton's broader claim about the superficiality of Christianity in Africa.
    • Hairspray Lighting Design: From Concept to Production

      Causer, Arthur Shon; Duer, Fred M.; Reynolds, Peter R. (Temple University. Libraries, 2017)
      This thesis document will chronicle the entire lighting design process of Temple University Theatre Department’s fall 2016 production of Hairspray. The process will be composed of four sections: research and analysis, preliminary documents, implementation and production, and archiving the design. In addition, this thesis will define both my personal and production goals in relation to my educational progression while studying at Temple University as well as discussing my personal growth within the program.
    • "HANDS ACROSS THE SEA": THE ANGLO-AMERICAN MILITARY RELATIONSHIP, 1917-1941

      Urwin, Gregory J. W., 1955-; Lockenour, Jay, 1966-; Ryan, Eileen, 1978-; Biddle, Tami Davis, 1959- (Temple University. Libraries, 2019)
      This dissertation analyzes the relationship that developed between the British Army and the United States Army between 1917 and 1941. Although those two forces operated as allies during World War I, both nations’ leaders grew frustrated with each other following the Armistice and the Treaty of Versailles. Officers in both armies built on their positive wartime experiences, however, to ensure their armies viewed each other as prospective allies should a future global conflict arise. In the two decades after World War I, personal exchanges initiated by individual officers and information sharing between these two armies improved relations and encouraged cooperation in a number of areas. The resulting cordiality that spread to a majority of the officers in both armies manifested itself in their socializing, reports, war plans, professional journals, and personal papers. Long before President Franklin Roosevelt and Prime Minister Winston Churchill took steps toward forming the Anglo-American alliance during World War II, their nations’ armies laid the military foundation for the special relationship.
    • Hanya Holm in America, 1931-1936: Dance, Culture and Community

      Bond, Karen E.; Kant, Marion; Kahlich, Luke C.; Dils, Ann (Temple University. Libraries, 2008)
      Though she is widely considered one of the "four pioneers" of American modern dance, German-American Hanya Holm (1893-1992) occupies a shadowy presence in dance history literature. She has often been described as someone who fell in love with America, purged her approach of Germanic elements, and emerged with a more universal one. Her "Americanization" has served as evidence of the Americanness of modern dance, thus eclipsing the German influence on modern dance. This dissertation challenges that narrative by casting new light on Holm's worldview and initial intentions in the New World, and by articulating the specifics of the first five years of her American career. In contrast to previous histories, I propose that Holm did not come to the U.S. to forge an independent career as a choreographer; rather, she came as a missionary for Mary Wigman and her Tanz-Gemeinschaft (dance cultural community). To Wigman and Holm, dance was not only an art form; it was a way of life, a revolt against bourgeois sterility and modern alienation, and a utopian communal vision, even a religion. Artistic expression was only one aspect of modern dance's larger purpose. The transformation of social life was equally important, and Holm was a fervent believer in the need for a widespread amateur dance culture. This study uses a historical methodology and accesses traces of the past such as lectures, school reports, promotional material, newspaper articles, personal notebooks, correspondence, photographs, and other material--much of it discussed here for the first time. These sources provide evidence for new descriptions and interpretations of Holm's migration from Germany to the U.S. and from German dance to American dance. I examine cultural contexts that informed Holm's beliefs, such as early twentieth century German life reform and body culture; provide a sustained analysis of the curriculum of the New York Wigman School of the Dance; and consider how the politicization of dance in the 1930s--in both Germany and the U.S.--affected Holm and her work.
    • HAPTIC HAPPENINGS: AN EXPLORATION OF SOUND, QUIET AND BLACKNESS

      Johnson, Amari (Temple University. Libraries, 2018)
      This research analyzes the lives and works of Black visual artists and filmmakers as visual representations of haptic events. This thesis examines how the lives of the artists and specific works of art are entangled with sound and quiet and directly reflect and shape the complexities black interiority. The possibilities of the black interior expand when the senses are combined and how the utilization of that synthesis centers the interior lives, ideas and art of black people. Centering the interior life creates space for the humanity of black people to be fully realized and explored without disruption both individually and collectively. Artists Jean-Michel Basquiat, David Hammons, Nick Cave and filmmakers Arthur Jafa and Kahlil Joseph’s work is used to illustrate how a haptic event is formed, how the haptic event effects both the artist and the audience and how the outcome of the haptic informs the present moment and often surpass the confines of language. This project extends the concept of Hapticality and the futurity of black interior life as a site of reflection, expression and resistance.
    • Harnack Inequality for a class of Degenerate Elliptic Equations in Non-Divergence Form

      Gutiérrez, Cristian E., 1950-; Berhanu, Shiferaw; Yang, Wei-shih, 1954-; Futer, David; Hynd, Ryan (Temple University. Libraries, 2018)
      We provide two proofs of an invariant Harnack inequality in small balls for a class of second order elliptic operators in non-divergence form, structured on Heisenberg vector fields. We assume that the coefficient matrix is uniformly positive definite, continuous, and symplectic. The first proof emulates a method of E. M. Landis, and is based on the so-called growth lemma, which establishes a quantitative decay of oscillation for subsolutions. The second proof consists in establishing a critical density property for non-negative supersolutions, and then invoking the axiomatic approach developed by Di Fazio, Gutiérrez and Lanconelli to obtain Harnack’s inequality.
    • HCV, Heroin Use, and MicroRNAs

      Ho, Wen-zhe; Ramirez, Servio H.; Kolson, Dennis L.; Shore, Scott K.; Rawls, Scott M. (Temple University. Libraries, 2014)
      Hepatitis C virus (HCV) infection is common among injection drug users (IDUs). There is accumulating evidence that circulating microRNAs (miRNAs) are related to HCV infection and disease progression. The present study was undertaken to determine the in vivo impact of heroin use on HCV infection and HCV-related circulating miRNA expression. Using the blood specimens from four groups of study subjects (HCV-infected individuals, heroin users with/without HCV infection, and healthy volunteers), we found that HCV- infected heroin users had significantly higher viral load than HCV-infected non-heroin users (p=0.0004). Measurement of HCV-related circulating miRNAs in plasma showed that miRs-122, 141, 29a, 29b, and 29c were significantly increased in the heroin users with HCV infection, whereas miR-351, an HCV inhibitory miRNA, was significantly decreased in heroin users as compared to control subjects. Further investigation identified a negative correlation between the plasma levels of miR-29 family members and severity of HCV infection based on aspartate aminotransferase to platelet ratio index (APRI). Heroin use and/or HCV infection also dysregulated a panel of plasma miRNAs. Taken together, these data for the first time revealed in vivo evidence that heroin use and/or HCV infection alter circulating miRNAs, which provides a novel mechanism for the impaired innate anti-HCV immunity among IDUs. Recent studies revealed that extracellular miRNAs were able to incorporate into cell-derived exosomes as a method of cell-to-cell interaction. Exosomes are a class of cell-released small vesicles that mediate intercellular communication by delivering functional factors to recipient cells. During HCV infection, the interaction between liver resident macrophages and hepatocytes is important for host defense and viral elimination, triggered by innate immune activation, especially Toll like receptors (TLR). In our study, we explored the role of macrophage-derived exosomes in the transmission of innate immune responses against HCV infection in hepatocytes, and the involvement of exosomal miRNAs in transferring the anti-HCV activities. We reported that upon TLR3 activation, macrophages shed exosomes that were able to attenuate HCV-JFH1 infection in Huh7 cells. We further demonstrated that exosomes from poly I:C treated macrophages were internalized by Huh7 cells, which induced the intercellular anti-HCV responses (type I interferon, interferon stimulated genes, etc.) and thus drastically inhibited HCV infection in Huh7 cells. Moreover, using an in vitro macrophage and Huh7 cell co-culture model, we also found exosomes mediated HCV suppression in Huh7 cells after TLR3 activation. The presence of exosome inhibitor in co-culture compromised the anti-HCV activity by TLR3-activated macrophages. Interestingly, the miRNA-29 family, which was reported to suppress HCV infection, was significantly increased in the macrophage exosomes after TLR3 activation. The inhibition of miRNA-29 partially compromised the anti-HCV activity of TLR3-activated macrophages, indicating the potential involvement of exosomal miRNAs in the transmission of anti-HCV activity from macrophages to Huh7 cells through exosomes. In conclusion, this study proposed an antiviral mechanism of TLR3 activation that involves the intercellular communication between immune cells and hepatic parenchymal cells via exosomes, and exosomal miRNAs. This discovery sheds light on exploiting the therapeutic potential of new drugs against HCV infection.
    • "HE WAS DESPISED" IN WRITING AND PERFORMANCE: A STUDY OF VOCAL ORNAMENTATION IN ONE ARIA FROM HANDEL'S MESSIAH USING OBJECTIVE AND SUBJECTIVE LISTENING PRACTICE

      Anderson, Christine L.; Cho, Philip Y.; Zohn, Steven David, 1966-; Bolton, Beth M. (Temple University. Libraries, 2010)
      A two-fold analysis of the vocal ornamentation in Handel's aria, "He was despised" from Messiah, was conducted employing objective and subjective forms of listening practice associated with the analysis of recordings methodology. It is this author's hypothesis that prosody, born of the semiotic processes of rhythm, pitch and accent, and which is also reflective of the subjective understanding of the performer, will be present during the moment of an ornament--if it is present at all in any performance. Ornamentation is shown to be an entry into the world of subjectivity in Baroque vocal performance practice as well as a window into the oral tradition and the primacy of the singer's expressiveness that relates back to the Italian school to which Handel subscribed. The method of study in this monograph consists of examining scholarly writings, scores, notations and most importantly, applying listening practice to 38 different renditions of "He was despised," executed by female altos or by countertenors, under the direction of various conductors, dating from 1927 through 2006. The first of two listening practices is an analysis of recordings to identify and review the nature of the non-notated sung ornaments found in the recordings. The author develops a system of defining and categorizing the types and units of non-notated, aurally observed vocal ornaments executed in each performance. In the second phase of this study, the author incorporates a postmodern philosophical approach and notes her own subjective experiences during the analysis of recordings. This phase examines the idea that prosodic elements are associated with the subjective experience of emotional meaning, elucidation of text, and illumination of subtext in this aria from Handel's Messiah. Results include noteworthy findings about the interplay of the singer's subjectivity with ornamentation in affecting the listener's subjective reaction to the performance (e.g., narrator's viewpoint, beautifying versus emphasizing subtext). In conclusion, the author explores the relationship between a performer's prosodic and non-prosodic executions of ornamentation and proposes specific recommendations to singers who wish to execute ornamentation in a manner that is both historically informed as well as prosodically expressive of subtext.
    • Health Care for Undocumented Immigrants and Their Children in the United States: an Ethical Dilemma

      Jones, Nora L. (Temple University. Libraries, 2020)
      Undocumented immigrants in the United States currently do not have the same access to health care as their legal and citizen counterparts. This is wrong, and both state and national governments bear responsibility in remedying this situation by expanding policies to include them to protect their rights, especially undocumented immigrant children as a special vulnerable population. In order to demonstrate this, I will discuss the historical barriers that immigrants have encountered when trying to access to health care. I will review the laws and policies that have excluded them from welfare programs and inflicted fear into discouraging them from using what is available. I will examine the ways in which children have been treated at the Southern border detention centers and show evidence that they have been historically abused and traumatized at these facilities while the government continues to promote discrimination, injustice, and hostility in the ways that immigrants are portrayed and treated. I will explore the ethical problems surrounding these issues by considering ideas of influential philosophers and bioethicists regarding health care as a right for all and question the philosophical basis for treating undocumented immigrants differently than the rest of the population. With the support of international law and bioethics I will argue that children are a vulnerable population that deserves special protection regardless of immigration laws. Finally, I will discuss the importance of intervening in this situation and describe ways in which the government, health care providers, and the general population can all contribute to promoting equality for all.
    • HEALTH INSURANCE DESIGN AS A DETERMINANT OF BARIATRIC SURGERY UTILIZATION

      Sarwer, David B.; Ibrahim, Jennifer; Aaronson, William Edson; Martin, Thomas R. (Temple University. Libraries, 2021)
      Background: Bariatric surgery is the most effective treatment for severe obesity, resulting in much larger and longer-lasting weight loss compared with those seen with other treatment options. It also results in significant improvements in several weight-related comorbidities. Despite these favorable outcomes, bariatric surgery remains underused in the United States. Objective: The goal of this dissertation was to investigate the impact of insurance-related factors on the access and utilization of bariatric procedures. The goal was achieved via three studies. The first study examined temporal changes in patient characteristics and insurer type mix among adult bariatric surgery patients in Southeastern Pennsylvania, as well as the associations between payer type, insurance plan type, cost-sharing arrangements (among traditional Medicare beneficiaries), and bariatric surgery utilization. The second study investigated whether there is an association between precertification criteria, such as 3-6 months preoperative supervised medical weight management (MWM), and documented 2-year weight history and the likelihood of undergoing bariatric surgery. The third study examined whether there is an association between insurance-mandated MWM requirement, as well as cardiology and pulmonology evaluations and short-term inpatient healthcare utilization. Data Source: Pennsylvania Health Care Cost Containment Council’s (PHC4) databases in Southeastern Pennsylvania during 2014-2018. Study Population: In Study 1, all adult patients in the PHC4 dataset who underwent the most common types of bariatric surgery during 2014-2018 (N = 14,348) and a 1:1 matched sample of surgery patients and those who were eligible for surgery but did not undergo surgery were identified. In Study 2, privately insured patients within the PHC4 dataset who underwent bariatric surgery in 2016 and individuals who met the eligibility criteria but did not undergo surgery were identified and 1:1 matched (N = 1,054). The population of Study 3 consisted of all adult patients within the PHC4 dataset with a diagnosis of severe obesity who underwent the most common bariatric surgical procedures in 2016 and for whom the insurance-mandated precertification requirements were known (N = 2,717). Results: Over the five years, there was an increase in the proportion of Black individuals (37.1% in 2014 vs 43.0% in 2018), Hispanics (5.4% vs 8.0%), and Medicaid beneficiaries (18.5% in 2014 vs 26.9% in 2018) who underwent surgery. The odds of undergoing bariatric surgery based on payer type were statistically different (22% smaller odds) only between Medicare beneficiaries compared to privately insured individuals. There were significantly different odds of undergoing surgery based on insurance plan type within Medicare and private insurance payer categories. Individuals with traditional Medicare plans with no supplementary insurance and those with dual eligibility had smaller odds of undergoing surgery (42% and 32%, respectively) compared to those with private secondary insurance. The insurance requirement for 3-6 months MWM was associated with smaller odds of undergoing surgery (odds ratio [OR] = 0.459, 95% confidence interval [CI] 0.253 to 0.832, P = 0.010), after controlling for insurance plan type and the requirement for documented weight history. The documented weight history requirement was not a significant predictor of the odds of undergoing surgery (P = 0.132). The requirement for MWM, as well as pulmonology and cardiology examinations, were not associated with the patient length of stay, the number of all-cause rehospitalizations, and the number of all-cause rehospitalization days, after adjusting for patient age, sex, race, ethnicity, the Elixhauser Comorbidity Score, type of the surgery, facility where the surgery was performed, primary payer type, and the estimated median household income. The absence of the precertification requirement for pulmonology and cardiology evaluations was associated with smaller odds of rehospitalizations with common cardiac and pulmonary conditions during the study period, (OR = 0.43, 95% CI 0.23 to 0.80, P = 0.008), after controlling for patient age, sex, race, ethnicity, estimated median household income, and the Elixhauser Comorbidity Score. Conclusions and Significance: Medicaid expansion in Pennsylvania appears to have improved access to bariatric surgery among Black and Hispanic individuals. Nevertheless, insurance plan type, cost-sharing arrangements, and precertification requirements, such as insurance-mandated 3-6 months of MWM requirement, remain key determinants for the access and utilization of bariatric surgery. Additionally, the MWM requirement, as well as the preoperative cardiology and pulmonology evaluations, were not associated with a reduction in inpatient healthcare utilization during the first postoperative year. Careful examination of the bariatric surgery benefit design and application of value-based insurance design to bariatric surgery may improve the access to this potentially life-saving surgery for many Americans.
    • Health Literacy, its Effect on Emergency Department Utilization, and a Smartphone-based Intervention

      Reeves, Kathleen A.; Jones, Nora L. (Temple University. Libraries, 2018)
      Health literacy is not only the ability to read, but also the ability of an individual to obtain, process, and understand the basic health information needed to make appropriate health decisions. Over time the concept of health literacy has evolved from considering it a risk factor to be managed to considering it an asset which can be continually built upon. With this in mind health professionals should continue to communicate in simple language, but should also provide their patients with high-quality educational materials and aid them in making the best choices about their health. One way to do this could be with the use of symptom-checking and decision-aiding smartphone apps. In this study, the primary caretakers of children aged 30 months and younger with publicly funded health insurance will be randomized to receive a pediatric symptom-checking smartphone app or a developmental milestone smartphone app. Caretaker health literacy will be measured, and data will be collected on emergency department and primary care office sick visits. It is hypothesized that the use of the pediatric symptom-checking smartphone app will decrease non-urgent visits to the pediatric emergency department.
    • HEALTH-RELATED QUALITY OF LIFE AMONG COMMUNITY-BASED OFFENDERS: HOW ‘WELL-BEING’ AFFECTS SUBSTANCE ABUSE TREATMENT ENGAGEMENT

      Belenko, Steven R.; Wood, Jennifer, 1971-; Welsh, Wayne N., 1957-; Ward, Jeffrey T.; Taxman, Faye S. (Temple University. Libraries, 2019)
      Substance use disorders (SUDs) among community-based offenders are a significant challenge for criminal justice agencies. SUDs are linked with both adverse health risks and increased risk of recidivism. Given the consequences of SUDs, mandated substance use treatment is often required in community supervision. Unfortunately, relapse is extremely common regardless of whether treatment is a condition of supervision. Previous research has identified some factors that can influence treatment outcomes among offender populations, including demographic differences, substance use history, mental health conditions, and criminal history. This dissertation will argue that a more nuanced understanding of the role of health and well-being among community-based offenders is a necessary component in understanding treatment engagement. Health Related Quality of Life (HRQOL), a construct to gauge health and well-being, is often used among medical communities to better understand health impacts on a given population as well as decision-making in treatment compliance studies. However, HRQOL is rarely studied in criminal justice, and has almost never been examined in community offender populations. A robust understanding of health is needed for this population of vulnerable offenders, an understanding that includes multiple dimensions of health including HRQOL. This study sampled a total of 103 offenders from drug court and probation settings, who were mandated to participate in substance use treatment. The health and treatment experiences of this sample of offenders were examined using mixed methods, beginning with quantitative analyses including descriptive, bivariate, multivariate statistical models and structural equation models. The multivariate models and structural equation models examined two main treatment engagement outcomes: whether offenders stayed in treatment and the proportion of treatment sessions attended. These quantitative findings were followed by qualitative analysis of 10 interviews with a subsample of the survey participants who had experienced some level of health difficulty at their baseline survey. Qualitative analyses sought to elaborate on the quantitative findings to provide context for how and why participants were or were not engaging with their mandatory treatment. Results from the quantitative analysis indicate that although criminal history is the most consistent factor influencing treatment engagement, various aspects of health appear to influence treatment success to some extent. HRQOL may influence whether participants stay in treatment. Treatment experiences and health also appear to differ substantially depending on the offenders’ primary drug of use. Offenders who exclusively used marijuana were substantially healthier than their harder drug using peers, and they appear to stay in treatment more easily. Furthermore, both mental and physical health conditions appear to influence treatment attendance among participants who used drugs other than exclusively marijuana. Finally, there were differences in treatment retention depending on whether participants were supervised by drug court or probation, such that drug court participants were more likely to stay in treatment; however, supervision type did not influence proportion of treatment sessions attended. Qualitative findings both provided support for some of the quantitative findings and also illuminated the nuances of the treatment engagement experience of offenders with health difficulties. Interviewees who primarily used marijuana tended to have less severe health difficulties and many did not perceive their use as problematic. Treatment engagement among participants was influenced by their motivation for treatment, whether they had mental health and/or physical health difficulties and the severity of those health difficulties. Logistical factors also influenced treatment engagement, particularly conflicts between treatment requirements and employment and familial relationships. Many of the results presented herein are exploratory and thus require replication; however, some clear directions for future research arise. There is a need to examine the role of health among community based offenders and their ability to comply with mandated treatment with a larger sample. In particular, studies are needed, which include more participants who use ‘harder’ illicit drugs such as opioids and cocaine, as they appear to have more difficulties both with their health and with treatment engagement. Further research is needed on models for Treatment Engagement that include multiple dimensions of health and allow for recursive relationships between health dimensions. Regarding policy and practice implications, the correctional agencies involved should consider re-evaluating the means by which offenders are assigned to supervision and SUD treatment. In particular methods for screening and assessment of SUDs should be re-evaluated, with particular consideration given to the role of offenders’ primary drug of use.
    • Health-Related Quality of Life In Kuwait: Validation of Generic and Disease-Specific Measures

      Hack, Laurita Mary; Barbe, Mary F.; Gordon, Thomas F.; Landry, Michel; Safadi, Fayez F. (Temple University. Libraries, 2008)
      Chronic diseases such as diabetes have become increasingly prominent around the world. Diabetes care requires a combination of medication, exercise, diet, self-management education, and psychosocial care to reduce the risk of long-term complications. Following this strict regimen can have an adverse effect on the patient's quality of life. Quality of life is a broad concept that is difficult to define and study. This study focused on the health-related component of quality of life. Diabetes is reaching epidemic proportions in Kuwait. While the incidence of the disease is documented, little is known about its effect on the life of the Kuwaiti population. This is partly due to the lack of valid Arabic versions of health-related quality of life (HRQOL) instruments. The purpose of this study was to investigate the construct validity of two HRQOL measures in a sample of older adults in Kuwait with Type 2 diabetes. The two measures were the Short Form 36-Item Health Survey version 2.0, a generic measure, and the Problem Areas in Diabetes survey, a disease-specific measure. A total of 240 Kuwaiti citizens over the age of 55 years living in Kuwait City participated in this study. Participants were divided into two groups: the Diabetes Group included 120 older adults with diabetes and the Control Group included 120 older adults without diabetes. Three approaches were used to assess the construct validity of the Arabic versions of the SF-36v2 Health Survey and the Problem Areas in Diabetes survey: factor analysis, correlation, and known-group method. The results of this study support the use of the Arabic versions of the two surveys to measure HRQOL of older adults in Kuwait with Type 2 diabetes. Standards for construct validity were well met, with few exceptions.
    • Hearing the Sublime: Signification of the Sublime in Solo Piano Literature of the Nineteenth Century

      Zohn, Steven David, 1966-; Klein, Michael Leslie; Abramovic, Charles; Latham, Edward David (Temple University. Libraries, 2019)
      Though many philosophers and music theorists have admitted the signification of the sublime in music as a possibility, the nature and mechanism of that signification has not yet been treated at length with a methodology familiar to musicians or native to music theory. Within this dissertation I have conducted a survey of the philosophy of the sublime as understood by Edmund Burke (1729 – 1797), Immanuel Kant (1724 – 1804), Friedrich Schiller (1759 – 1805), and Arthur Schopenhauer (1788 – 1860), with references to other contemporary philosophers and writers. The broader influence of the sublime in regards to German-speaking regions and certain musical composers was also considered. I then gathered from the above philosophers’ categories and definitions of the sublime a constellation of objects, qualities, and emotional states associated with the sublime. These functioned as signs or signifiers of the sublime, whose paths of signification were considered or determined with use of semiotics and topic theory, with reference to the work of Danuta Mirka, Raymond Monelle, and Leonard Ratner. Making reference to score examples listed in the list of figures, I implemented these techniques in analyses of Ludwig van Beethoven’s Sonata No. 30 in E Major, Op. 109 and Sonata No. 32 in C, Op. 111 as well as Franz Liszt’s “Mazeppa,” from the Études d’exécution transcendante, “Funerailles” from Harmonies Poétiques et Religieuses III, S. 173, and “Marche funèbre, En mémoire de Maximilian I, Empereur du Mexique” in from Années de pèlerinage III, S.163.
    • HEAT PUMP AND AIR CONDITIONING SYSTEM ANALYSIS BASED ON VARIABLE SPEED COMPRESSOR

      Chen, Shih-Jiun; Cohen, Richard; Ridenour, Steven M. (Temple University. Libraries, 2010)
      Experiments were carried out to investigate the effect of ambient air temperatures on the heat pump performance using a variable speed compressor. Ambient air temperatures were varied from 40 to 60 °F to simulate different seasons. The compressor frequencies of 45 Hz, 50 Hz, 55 Hz, and 60 Hz were studied to determine the optimal frequency under various heating loads. The investigation was carried out by showing the compressor power input, heating output, and coefficient of performance for each case. Thermal cycle analysis along with the heat exchanger theory was used to analyze the system energy balance, heat transfer rates, p-h diagrams, and coefficient of performance. The overall heat transfer coefficients were also determined for both the evaporator and the condenser. Only the capillary tube was used to regulate the refrigerant flow rate. The variable speed compressor system used in this study will help save energy when compared with the traditional steady speed system. The variable speed compressor system will hopefully provide a more comfortable and steady indoor temperature than the traditional system, which is controlled by only an on-off switch. The speed controlled compressor system proposed we believe will help saving more energy than traditional steady speed system. The variable speed compressor system will hopefully provide a more comfort and steady indoor temperature than the traditional system which is controlled by one switch. It is believed that the variable speed compressor system may allow the indoor temperature air to be steady-going and prevent the switch working frequently.
    • Heating Up and Cooling Out at the Community College: The Potential of Student-Faculty Interactions to Contribute to Student Aspiration

      Horvat, Erin McNamara, 1964-; Shaw, Kathleen M.; Caldwell, Corrinne A.; Jordan, Will J.; Goyette, Kimberly A. (Temple University. Libraries, 2009)
      This study examines the potential of faculty at the community college to positively influence, or "heat up," student aspirations. With increasing emphasis on graduation and transfer rates in higher education, the importance of micro-level interactions that shape student aspiration has been neglected. To better understand how individuals within the institution, especially faculty, contribute to student aspirations, this study attempts to bridge the "cooling out" and "heating up" literature in the context of the modern community college by recognizing the role of the individual academic program. Applying organizational theory from a systems perspective, as well as the theories of Paolo Freire, the study examines the nature of student-faculty interactions that have the potential to contribute to student aspiration in the context of institutional limitations. The participants include students and faculty in three academic programs that have different approaches to student success within one urban community college. The case study involves a combination of qualitative approaches, including interviews and observations. The study inductively examines student-faculty interactions and their potential to contribute to student aspirations within three different academic programs. The most significant barriers to student success and increasing aspirations are found on the institutional level. These limitations, including bureaucratic confusion, advisement issues, remediation, variation in attendance policies, financial constraints, and lacking a cohesive institutional culture and commitment, have the potential to "cool out" student aspiration, as supported in the majority of the community college literature on this topic. However, the mezzo-level effects of programs and the micro-level practices of the individuals hold substantial potential in terms of "heating up" student aspiration. Programs vary in the degree to which they handle the institutional limitations. Programs that take an active role in mediating between the limiting institutional barriers and students provide a cushioning program-wide protection from the cooling out elements. The micro-level interactions between individual students and faculty also hold potential to heat up by helping students navigate the systematic confusion that seems characteristic of the community college. Therefore, this study suggests that there is hope for the community college in fulfilling its promise of educational opportunity. Macro-level institutional challenges, as well as larger societal inequalities, are substantial and pervasive at the community college and solutions are often limited by financial constraints. However, the programs and individuals within the community college hold promise. The study suggests that the roles of the program and the individual are instrumental in shaping student aspiration.
    • Hecke Correspondence for Automorphic Integrals with Infinite Log-Polynomial Periods

      Knopp, Marvin Isadore, 1933-; Datskovsky, Boris Abramovich; Berhanu, Shiferaw; Mendoza, Gerardo A.; Pribitkin, Wladimir (Temple University. Libraries, 2012)
      Since Hecke first proved his correspondence between Dirichlet series with functional equations and automorphic forms, there have been a great number of generalizations. Of particular interest is a generalization due to Bochner that gives a correspondence between Dirichlet series with any finite number of poles that satisfy the classical functional equation and automorphic integrals with (finite) log-polynomial sum period functions. In this dissertation, we extend Bochner's result to Dirichlet series with finitely many essential singularities. With some restrictions on the underlying group and the weight, we also prove a correspondence for Dirichlet series with infinitely many poles. For this second correspondence, we provide a technique to approximate automorphic integrals with infinite log-polynomial sum period functions by automorphic integrals with finite log-polynomial period functions.
    • Hedonic Functioning and Subthreshold Psychotic Symptoms

      Ellman, Lauren M.; Fauber, Robert L.; Alloy, Lauren B.; Giovannetti, Tania; McCloskey, Michael S.; Johnson, Kareem (Temple University. Libraries, 2013)
      Schizophrenia is a debilitating disorder with an array of affective, cognitive, and behavioral consequences. In addition to these impairments, research suggests that there is a distinct pattern of hedonic functioning in schizophrenia that may contribute to some of the most intractable symptoms of the disorder, the negative symptoms. Specifically, individuals with schizophrenia appear to experience deficient levels of pleasure during anticipation of a pleasurable stimulus, while experiencing typical levels of pleasure while directly engaged with a pleasurable stimulus. Despite these findings, it is unclear whether hedonic functioning deficits occur in individuals with subthreshold levels of psychotic symptoms and/or in individuals at clinical high risk for the disorder. The purpose of this study was to examine hedonic functioning in relation to the continuum of psychotic symptoms in a college undergraduate student sample, and in those at clinical risk for schizophrenia. Participants were 679 students who completed self-report measures of current psychotic-like experiences, and trait-like components of hedonic functioning (i.e., anticipatory and consummatory pleasure). Consistent with study hypotheses, deficits in anticipatory pleasure, but not in consummatory pleasure, were significantly associated with increased clinical risk for schizophrenia. However, this relation was found exclusively among women in the sample, whereas men did not show a significant relation between anticipatory pleasure deficits and clinical high-risk. Furthermore, anticipatory pleasure deficits were not significantly associated with increases in the number of positive psychotic symptoms endorsed. Moreover, consummatory pleasure was not associated with increases in the number of subthreshold positive psychotic symptoms, nor was there a relation with the number of distressing positive psychotic symptoms or clinical risk status. The present study provides the first examination of the relation between hedonic functioning and subthreshold psychotic symptoms, as well as the relation with clinical high-risk for psychosis. These findings suggest that anticipatory pleasure deficits may be more closely related to increased clinical risk for psychosis among women rather than increases in psychotic symptoms in the general population. Anticipatory pleasure deficits may be a useful target for intervention and prevention techniques among those at clinical risk for psychosis, especially in female at risk populations. Additional longitudinal studies will be essential for testing whether anticipatory pleasure deficits predict the occurrence of future psychotic disorders among those at high risk for the disorder in order to improve early identification and early intervention efforts in this population.