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HIV-Associated Neurocognitive Disorders: The Relationship of HIV Infection with Physical and Social Comorbidities
Minniti, Nancy L. Fischer, Tracy
Minniti, Nancy L.
Fischer, Tracy
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Journal article
Date
2015-03-01
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Medicine
Neuroscience
Neuroscience
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https://doi.org/10.1155/2015/641913
Abstract
The prevalence of HIV (human immunodeficiency virus) associated neurocognitive disorders (HAND) will undoubtedly increase with the improved longevity of HIV-infected persons. HIV infection, itself, as well as multiple physiologic and psychosocial factors can contribute to cognitive impairment and neurologic complications. These comorbidities confound the diagnosis, assessment, and interventions for neurocognitive disorders. In this review, we discuss the role of several key comorbid factors that may contribute significantly to the development and progression of HIV-related neurocognitive impairment, as well as the current status of diagnostic strategies aimed at identifying HIV-infected individuals with impaired cognition and future research priorities and challenges.
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Citation
Feldman, A.M., Begay, R.L., Knezevic, T., Myers, V.D., Slavov, D.B., Zhu, W., Gowan, K., Graw, S.L., Jones, K.L., Tilley, D.G., Coleman, R.C., Walinsky, P., Cheung, J.Y., Mestroni, L., Khalili, K. and Taylor, M.R.G. (2014), Decreased Levels of BAG3 in a Family With a Rare Variant and in Idiopathic Dilated Cardiomyopathy. J. Cell. Physiol., 229: 1697-1702. https://doi.org/10.1002/jcp.24615
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BioMed Research International, Volume 2015
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