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Monte Carlo Dose Calculation – A QA Method for SRT and SBRT Plans in Treating Multiple and Small Metastatic Lesions

Lin, Teh
Ma, C-M Charlie
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Journal article
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2022-03-31
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http://dx.doi.org/10.4103/jmp.jmp_123_21
Abstract
To provide accurate and fast 3-D dose verification for hypofractionated stereotactic radiotherapy (SRT/SBRT) of small and multi targets calculated with a Varian Eclipse treatment planning system (TPS) delivered on a Varian accelerator. Ten brain and lung hypofractionated SRT/SBRT linac-based and CyberKnife plans were generated by the Eclipse system for delivery on the accelerator with the Millenium-120 leaf multileaf collimator (MLC) and Multiplan for the CyberKnife machine. These clinical SRT/SBRT plans required accurate quality assurance measurements to obtain absolute point dose and 3-D dose distributions due to the low number of fractions and high fraction doses. For small-field and multi-target plans, the EGS4/MCSIM code was used to calculate the dose distribution. A 0.125 cc ion chamber, a 0.016 cc pin-point chamber and Kodak EDR2 film were used for the measurements and the results were compared with Monte Carlo (MC) calculations. The dosimetry for small-field and multi-target treatment plans is challenging due to the comparable range of secondary electrons and the field sizes defined by SRT/SBRT MLC segments. Our MC simulations can accurately reproduce the linac dose distributions (within 1%/1 mm) three dimensionally. For the clinical SRT/SBRT plans investigated in this work, the MC doses agreed within 3% with ion chamber measurements and within 2%/2 mm with film measurements. The doses calculated by the Eclipse AAA algorithm and Multiplan differed by no more than 5% from MC calculations for small (4–40 cc) Planning Target Volumes (PTVs). MC dose calculation provides accurate and fast 3-D dose verification for hypofractionated SRT for small and multi-target treatment plans generated by a Varian Eclipse TPS on a Varian accelerator and Multiplan treatment planning on the CyberKnife System.
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Lin, Teh; Wang, Lu; Charlie, C-M Ma. Monte Carlo Dose Calculation – A QA Method for SRT and SBRT Plans in Treating Multiple and Small Metastatic Lesions. Journal of Medical Physics 47(1):p 99-104, Jan–Mar 2022. DOI: 10.4103/jmp.jmp_123_21
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Medknow Publications
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Journal of Medical Physics, Vol. 47
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