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Effects of Digoxin in Heart Failure (HF) With Reduced Ejection Fraction (EF)

Parikh, Riya R.
Patel, Khushbu R.
Pergolizzi, Joseph V.
Breve, Frank
Magnusson, Peter
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Journal article
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2022-03-02
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http://dx.doi.org/10.7759/cureus.22778
Abstract
In this review, we evaluated the literature on the benefits and deleterious effects of digoxin in heart failure (HF) with reduced ejection fraction (EF). Although digoxin was considered an effective treatment for HF, the supporting evidence is conflicting. Before the conventional use of modern HF therapies, digoxin was widely used for symptomatic relief on these patients. Further randomized trials are required to reach a definite conclusion about its efficacy and safety in patients experiencing HF with a reduced EF (HFrEF).
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Parikh R R, Patel K R, Pergolizzi J V, et al. (March 02, 2022) Effects of Digoxin in Heart Failure (HF) With Reduced Ejection Fraction (EF). Cureus 14(3): e22778. doi:10.7759/cureus.22778
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Cureus, Vol. 14
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