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Treating Apnea of Prematurity
Pergolizzi, Joseph Kraus, Alexander Magnusson, Peter Breve, Frank Mitchell, Kailyn Raffa, Robert LeQuang, Jo Ann K. Varrassi, Giustino
Pergolizzi, Joseph
Kraus, Alexander
Magnusson, Peter
Breve, Frank
Mitchell, Kailyn
Raffa, Robert
LeQuang, Jo Ann K.
Varrassi, Giustino
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Journal article
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2022-01-31
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http://dx.doi.org/10.7759/cureus.21783
Abstract
Premature babies often suffer apnea of prematurity as a physiological consequence of an immature respiratory system. Hypercapnia may develop, and neonates with apnea of prematurity are at an increased risk of morbidity and mortality. The long-term effects of apnea of prematurity or their treatments are less clear. While a number of treatment options exist for apnea of prematurity, there is no clear-cut “first-line” approach or gold standard of care. Effective treatments, such as caffeine citrate, carbon dioxide inhalation, nasal continuous positive airway pressure, nasal intermittent positive pressure ventilation, and others, may be associated with safety concerns. More conservative treatments are available, such as kangaroo care, postural changes, and sensory stimulation, but they may not be effective. While apnea of prematurity resolves spontaneously as the respiratory system matures, it can complicate neonatal care and may have both short-term and long-term consequences. The role, if any, that apnea of prematurity may play in mortality of preterm neonates is not clear.
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Pergolizzi J, Kraus A, Magnusson P, et al. (January 31, 2022) Treating Apnea of Prematurity. Cureus 14(1): e21783. doi:10.7759/cureus.21783
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Cureus, Vol. 14
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