Loading...
Extraterrestrial Gynecology: Could Spaceflight Increase the Risk of Developing Cancer in Female Astronauts? An Updated Review
Drago-Ferrante, Rosa Di Fiore, Riccardo Karouia, Fathi Subbannayya, Yashwanth Das, Saswati Mathyk, Begum Aydogan Arif, Shehbeel Guevara-Cerdán, Ana Paula Seylani, Allen Galsinh, Aman Singh
Drago-Ferrante, Rosa
Di Fiore, Riccardo
Karouia, Fathi
Subbannayya, Yashwanth
Das, Saswati
Mathyk, Begum Aydogan
Arif, Shehbeel
Guevara-Cerdán, Ana Paula
Seylani, Allen
Galsinh, Aman Singh
Citations
Altmetric:
Genre
Journal article
Date
2022-07-05
Advisor
Committee member
Department
Permanent link to this record
Collections
Research Projects
Organizational Units
Journal Issue
DOI
http://dx.doi.org/10.3390/ijms23137465
Abstract
Outer space is an extremely hostile environment for human life, with ionizing radiation from galactic cosmic rays and microgravity posing the most significant hazards to the health of astronauts. Spaceflight has also been shown to have an impact on established cancer hallmarks, possibly increasing carcinogenic risk. Terrestrially, women have a higher incidence of radiation-induced cancers, largely driven by lung, thyroid, breast, and ovarian cancers, and therefore, historically, they have been permitted to spend significantly less time in space than men. In the present review, we focus on the effects of microgravity and radiation on the female reproductive system, particularly gynecological cancer. The aim is to provide a summary of the research that has been carried out related to the risk of gynecological cancer, highlighting what further studies are needed to pave the way for safer exploration class missions, as well as postflight screening and management of women astronauts following long-duration spaceflight.
Description
Citation
Drago-Ferrante, R.; Di Fiore, R.; Karouia, F.; Subbannayya, Y.; Das, S.; Aydogan Mathyk, B.; Arif, S.; Guevara-Cerdán, A.P.; Seylani, A.; Galsinh, A.S.; et al. Extraterrestrial Gynecology: Could Spaceflight Increase the Risk of Developing Cancer in Female Astronauts? An Updated Review. Int. J. Mol. Sci. 2022, 23, 7465. https://doi.org/10.3390/ijms23137465
Citation to related work
MDPI
Has part
International Journal of Molecular Sciences, Vol. 23, Iss. 13
ADA compliance
For Americans with Disabilities Act (ADA) accommodation, including help with reading this content, please contact scholarshare@temple.edu