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Health-care resource use and costs associated with diabetic and idiopathic gastroparesis: A claims analysis of the first 3 years following the diagnosis of gastroparesis
Chen, Yaozhu J. Tang, Wenxi Ionescu-Ittu, Raluca Ayyagari, Rajeev Wu, Eric Huh, Susanna Y.
Chen, Yaozhu J.
Tang, Wenxi
Ionescu-Ittu, Raluca
Ayyagari, Rajeev
Wu, Eric
Huh, Susanna Y.
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Journal article
Date
2022-03-30
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Medicine
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http://dx.doi.org/10.1111/nmo.14366
Abstract
Background: Due to limited treatment options, many patients with diabetic gastroparesis (DG) or idiopathic gastroparesis (IG) experience inadequate symptom control resulting in increased health-care resource utilization (HRU) and associated costs. We compared all-cause HRU and health-care costs over the 3 years after patients’ first gastroparesis diagnosis with that of matched controls without gastroparesis. Methods: Newly diagnosed adults with DG or IG were identified in Optum's de-identified Clinformatics® Data Mart Database (Q1-2007 to Q1-2019). Patients with DG/IG were matched 1:1 to controls using a mixed approach of exact matching and propensity score matching. The index date was the first gastroparesis diagnosis for cases or randomly selected for controls. All-cause HRU and direct health-care costs per person-year (PPY) were compared between DG/IG cases and controls in Years 1–3 post-index. Key Results: Demographics and comorbidities were balanced between patients with gastroparesis (n = 18,015 [DG]; n = 14,305 [IG]) and controls. In each of the Years 1–3 post-index, patients with DG or IG had significantly higher annual HRU and costs versus controls (mean total cost differences PPY: DG Year 1 $34,885, Year 2 $28,071, Year 3 $25,606; IG Year 1 $23,176, Year 2 $16,627, Year 3 $14,396) (all p < 0.05). Across all 3 years, DG/IG cohorts had approximately twice the costs of controls. HRU and costs were highest in Year 1 post-index for both DG and IG. Conclusions & Inferences: The economic burden of gastroparesis remains high several years after diagnosis, emphasizing the need for chronic treatment to effectively manage symptoms and consequently reduce the burden of this disorder.
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Chen YJ, Tang W, Ionescu-Ittu R, et al. Health-care resource use and costs associated with diabetic and idiopathic gastroparesis: A claims analysis of the first 3 years following the diagnosis of gastroparesis. Neurogastroenterology & Motility. 2022; 34:e14366. doi:10.1111/nmo.14366
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Neurogastroenterology & Motility, Vol. 34, Iss. 9
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