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Cardiac Sarcoidosis Diagnostic Challenges and Management: A Case Report and Literature Review
Jaiswal, Richa ; Vaisyambath, Laseena ; Khayyat, Azadeh ; Unachukwu, Nkechinyere ; Nasyrlaeva, Bibimariyam ; Asad, Muhammad ; Fabara, Stephanie P. ; Balan, Irina ; Kolla, Sree ; Rabbani, Rizwan
Jaiswal, Richa
Vaisyambath, Laseena
Khayyat, Azadeh
Unachukwu, Nkechinyere
Nasyrlaeva, Bibimariyam
Asad, Muhammad
Fabara, Stephanie P.
Balan, Irina
Kolla, Sree
Rabbani, Rizwan
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Journal article
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2022-05-09
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http://dx.doi.org/10.7759/cureus.24850
Abstract
Sarcoidosis can be presented as cardiac sarcoidosis (CS), which is challenging to diagnose due to its clinical silence. Ventricular arrhythmias and atrioventricular blocks can be fatal and cause sudden death in patients with cardiac sarcoidosis. Five percent of sarcoidosis patients have clinically evident cardiac sarcoidosis. However, autopsy reports and imaging studies have shown a higher prevalence of cardiac involvement. Early recognition is important to prevent such detrimental consequences. Cardiac sarcoidosis is increasingly being diagnosed owing to increased awareness among physicians and new diagnostic tools like MRI and positron emission tomography (PET) scan replacing traditional endomyocardial biopsy. A definitive diagnosis of CS remains challenging due to the non-specific clinical findings that can present similar symptoms of common cardiac disease; therefore, the imaging and biopsies are substantial for diagnosis confirmation. Pharmacological and Implantable devices are two main therapeutic approaches in cardiac sarcoidosis, in which steroids and pacemaker therapy have shown better outcomes. This review summarizes the available data related to the prevalence, prognosis, diagnosis, and management of cardiac sarcoidosis.
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Jaiswal R, Vaisyambath L, Khayyat A, et al. (May 09, 2022) Cardiac Sarcoidosis Diagnostic Challenges and Management: A Case Report and Literature Review. Cureus 14(5): e24850. doi:10.7759/cureus.24850
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Cureus: Journal of Medical Science, Vol. 14
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