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A Hydrogel-Based Ultrasonic Backscattering Wireless Biochemical Sensing
Nam, J ; Byun, E ; Shim, H ; Kim, E ; Islam, S ; Park, M ; Kim, A ; Song, SH
Nam, J
Byun, E
Shim, H
Kim, E
Islam, S
Park, M
Kim, A
Song, SH
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Journal Article
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2020-11-27
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10.3389/fbioe.2020.596370
Abstract
© Copyright © 2020 Nam, Byun, Shim, Kim, Islam, Park, Kim and Song. Wireless monitoring of the physio-biochemical information is becoming increasingly important for healthcare. In this work, we present a proof-of-concept hydrogel-based wireless biochemical sensing scheme utilizing ultrasound. The sensing system utilizes silica-nanoparticle embedded hydrogel deposited on a thin glass substrate, which presents two prominent interfaces for ultrasonic backscattering (tissue/glass and hydrogel/glass). To overcome the effect of the varying acoustic properties of the intervening biological tissues between the sensor and the external transducer, we implemented a differential mode of ultrasonic back-scattering. Here, we demonstrate a wireless pH measurement with a resolution of 0.2 pH level change and a wireless sensing range around 10 cm in a water tank.
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