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Tracking adaptive evolutionary events in genomic sequences
Liberles, DA Wayne, ML
Liberles, DA
Wayne, ML
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Short Survey
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2002-07-02
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10.1186/gb-2002-3-6-reviews1018
Abstract
As more gene and genomic sequences from an increasing assortment of species become available, new pictures of evolution are emerging. Improved methods can pinpoint where positive and negative selection act in individual codons in specific genes on specific branches of phylogenetic trees. Positive selection appears to be important in the interaction between genotype, protein structure, function, and organismal phenotype.
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Springer Science and Business Media LLC
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Genome Biology
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