Loading...
Effect of malnutrition on outcomes of hospitalisations for acute pulmonary embolism: a national inpatient database study
Li, Si Wang, Yichen
Li, Si
Wang, Yichen
Citations
Altmetric:
Genre
Journal article
Date
2024-02-10
Advisor
Committee member
Group
Department
Medicine
Thoracic Medicine and Surgery
Thoracic Medicine and Surgery
Subject
Permanent link to this record
Collections
Research Projects
Organizational Units
Journal Issue
DOI
https://doi.org/10.1136/bmjnph-2023-000705
Abstract
Background: To evaluate the occurrence of malnutrition in pulmonary embolism (PE)-related hospitalisations and assess the impact of malnutrition on the outcomes of patients with PE. Methods: A retrospective observational study using data extracted from the Nationwide Inpatient Sample from 2016 to 2018. Hospitalisations with a principal diagnosis of PE were obtained using International Classification of Diseases, Tenth Revision codes and divided into groups based on a secondary diagnosis of malnutrition. Results: Of 563,135 PE hospitalisations, 30,495 (5.4%) had malnutrition. PE patients with malnutrition were older (mean age±SD, 69.1±14.5 vs 62.3±16.6, p<0.001) and with higher Charlson Comorbidity Index score (3 to 5, 24.8% vs 12.9%, p<0.001). Concurrent malnutrition was associated with higher adjusted OR (aOR) of in-hospital mortality (aOR 2.43, 95% CI 2.18 to 2.70, p<0.001), acute kidney injury (aOR 1.56, 95% CI 1.45 to 1.67, p<0.001), sepsis (aOR 4.37, 95% CI 3.79 to 5.03, p<0.001), shock (aOR 2.52, 95% CI 2.25 to 2.81, p<0.001), acidosis (aOR 2.55, 95% CI 2.34 to 2.77, p<0.001) and mechanical ventilation (aOR 2.95, 95% CI 2.61 to 3.33, p<0.001). Patients with PE and malnutrition had an increased mean length of stay (adjusted difference 3.39 days, 95% CI 3.14 to 3.65, p<0.001), hospital charges (adjusted difference US$34, 802.11, 95% CI US$31,005.01 to US$38,599.22, p<0.001) and costs (adjusted difference US$8,332.01, 95% CI US$7,489.09 to US$9,174.94, p<0.001). Conclusion: Concurrent PE and malnutrition were associated with worse outcomes. The study highlights the importance of identifying malnutrition in patients with PE to improve outcomes and reduce healthcare utilisation.
Description
Citation
Li S, Lio KU, Ho T, et alEffect of malnutrition on outcomes of hospitalisations for acute pulmonary embolism: a national inpatient database studyBMJ Nutrition, Prevention & Health 2023;6:doi: 10.1136/bmjnph-2023-000705
Citation to related work
BMJ Publishing Group
Has part
BMJ Nutrition, Prevention & Health, Vol. 6, Iss. 2
ADA compliance
For Americans with Disabilities Act (ADA) accommodation, including help with reading this content, please contact scholarshare@temple.edu