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Microwave Ablation for Malignant Central Airway Obstruction: A Pilot Study
Senitko, Michal Oberg, Catherine L. Abraham, George E. Hillegass, William B. Akhtar, Israh Folch, Erik
Senitko, Michal
Oberg, Catherine L.
Abraham, George E.
Hillegass, William B.
Akhtar, Israh
Folch, Erik
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Journal article
Date
2022-03-22
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Pathology and Laboratory Medicine
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DOI
http://dx.doi.org/10.1159/000522544
Abstract
Background: Malignant central airway obstruction (CAO) is a debilitating complication of primary lung cancer and pulmonary metastases. Therapeutic bronchoscopy is used to palliate symptoms and/or bridge to further therapy. Microwave ablation (MWA) heats tissue by creating an electromagnetic field around an ablation device. We present a pilot study utilizing endobronchial MWA via flexible bronchoscopy as a novel modality for the management of malignant CAO. Methods: Therapeutic bronchoscopy with a flexible MWA probe was performed in 8 cases. We reviewed tumor size, previous ablative techniques, number of applications, ablation time, amount of energy delivered, rate of successful recanalization, complications, and 30-day follow-up. Results: Successful airway recanalization was achieved in all cases. No complications were noted. In 1 case, tumor in-growth within a silicone stent was ablated with no damage to the stent. Discussion: Endobronchial MWA is a novel technique for tumor destruction while maintaining an airway axis. The oven effect and air gap around a tumor allow for safe and effective tissue devitalization and hemostasis without a thermal effect on structures surrounding the airway.
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Michal Senitko, Catherine L. Oberg, George E. Abraham, William B. Hillegass, Israh Akhtar, Erik Folch; Microwave Ablation for Malignant Central Airway Obstruction: A Pilot Study. Respiration 1 July 2022; 101 (7): 666–674. https://doi.org/10.1159/000522544
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Karger Publishers
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Respiration, Vol. 101, Iss. 7
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