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The role of PET in the management of sarcoidosis
Vender, Robert J. Aldahham, Hamad
Vender, Robert J.
Aldahham, Hamad
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Journal article
Date
2022-07-16
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Department
Thoracic Medicine and Surgery
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http://dx.doi.org/10.1097/mcp.0000000000000892
Abstract
Purpose of review: PET has emerged as method to determine the location and extent of disease activity in sarcoidosis. As most clinicians do not routinely utilize PET in the management of sarcoidosis, an understanding of the imaging technique is needed to comprehend the impact that PET abnormalities have on diagnosis, prognosis, and treatment. Recent findings: Although PET can detect inflammation because of sarcoidosis throughout the body, it is most often utilized for the diagnosis of cardiac sarcoidosis for which it may provide information about prognosis and adverse events. Whenever PET is combined with cardiac magnetic resonance (CMR), clinicians may be able to increase the diagnostic yield of imaging. Furthermore, PET abnormalities have the potential to be utilized in the reduction or augmentation of therapy based on an individual's response to treatment. Although various biomarkers are used to monitor disease activity in sarcoidosis, an established and reproducible relationship between PET and biomarkers does not exist. Summary: PET has the potential to improve the diagnosis of sarcoidosis and alter treatment decisions but prospective trials are needed to define the role of PET while also standardizing the performance and interpretation of the imaging modality.
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Citation
Vender, Robert J.a; Aldahham, Hamadc; Gupta, Rohitb. The role of PET in the management of sarcoidosis. Current Opinion in Pulmonary Medicine 28(5):p 485-491, September 2022. | DOI: 10.1097/MCP.0000000000000892
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Lippincott, Williams & Wilkins
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Current Opinion in Pulmonary Medicine, Vol. 28, No. 5
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