Loading...
Citations
Altmetric:
Genre
Thesis/Dissertation
Date
2024-08
Advisor
Committee member
Group
Department
Psychology
Permanent link to this record
Collections
Research Projects
Organizational Units
Journal Issue
DOI
http://dx.doi.org/10.34944/dspace/10682
Abstract
The ability to learn and predict threats in our environment has a direct impact onwhat and how we encode our experiences into future recollections. Experience of our
daily lives has implications for how we eventually gain long-term memory, adaptive
strategies to assess and foresee threats are crucial for survival. Yet, how humans encode
threat-related experiences is difficult to study in terms of episodic memory (Clewett &
Murty, 2019; Murty et al., 2012). From background literature, a model that focuses on
brain-related modulation at encoding which then is found to impact the formation and
recollection of episodic experience, our recent work has begun to characterize how
threat-related arousal either enhances or disrupts temporal order memory (Cliver et al.,
2024; Gregory & Murty, n.d.). In both behavioral (Study 1 and Study 2) and
neuroimaging (Study 2) analyses to investigate the relationship between threat-related
neural circuitry during encoding of short movie clips to test temporal order memory and
temporal distance memory. We measured neural circuitry in the medial temporal lobe
(MTL), including the amygdala sub-nuclei areas of the basolateral and the central-medial
amygdala, the anterior and posterior hippocampus, and the perirhinal cortex. We present
neural univariate signals of these regions of interest (ROIs), and functional connectivity
between ROIs (basolateral and central-medial amygdala, anterior and posterior
hippocampus, perirhinal cortex) to see successful temporal order memory performance
and compression or expansion of temporal distance memory. This work highlights the
importance of understanding neural processes of threat-related arousal encoding.
Description
Citation
Citation to related work
Has part
ADA compliance
For Americans with Disabilities Act (ADA) accommodation, including help with reading this content, please contact scholarshare@temple.edu